locus-tag	class	description
AZ49_RS00010	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AZ49_RS00015	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AZ49_RS00020	COG1115	amino acid carrier protein
AZ49_RS00030	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AZ49_RS00035	COG3206	protein involved in exopolysaccharide biosynthesis
AZ49_RS00040	COG1193	negative regulation of DNA recombination
AZ49_RS00045	COG0826	peptidase U32
AZ49_RS00050	COG1454	alcohol dehydrogenase
AZ49_RS00055	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AZ49_RS00060	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AZ49_RS00075	COG1104	cysteine desulfurase activity
AZ49_RS00150	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AZ49_RS00160	COG0698	ribose 5-phosphate isomerase
AZ49_RS00165	COG0009	L-threonylcarbamoyladenylate synthase
AZ49_RS00170	COG2890	protein-(glutamine-N5) methyltransferase activity
AZ49_RS00175	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AZ49_RS00180	COG3872	metal-dependent enzyme
AZ49_RS00185	COG0254	rRNA binding
AZ49_RS00190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AZ49_RS00195	COG0602	queuosine metabolic process
AZ49_RS00205	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AZ49_RS00210	COG0346	lactoylglutathione lyase activity
AZ49_RS00215	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AZ49_RS00220	COG0419	ATPase involved in DNA repair
AZ49_RS00230	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AZ49_RS00235	COG0735	belongs to the Fur family
AZ49_RS00240	COG2183	response to ionizing radiation
AZ49_RS00270	COG2217	Heavy metal translocating P-type atpase
AZ49_RS00280	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AZ49_RS00305	COG0861	Integral membrane protein TerC family
AZ49_RS00310	COG3875	lactate racemase activity
AZ49_RS00315	COG0277	FAD linked oxidase domain protein
AZ49_RS00320	COG1620	l-lactate permease
AZ49_RS00325	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AZ49_RS00340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZ49_RS00340	COG1116	anion transmembrane transporter activity
AZ49_RS00380	COG1619	proteins homologs of microcin C7 resistance protein MccF
AZ49_RS00385	COG4166	transmembrane transport
AZ49_RS00390	COG4608	Belongs to the ABC transporter superfamily
AZ49_RS00395	COG0444	Belongs to the ABC transporter superfamily
AZ49_RS00400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZ49_RS00405	COG0601	transmembrane transport
AZ49_RS00410	COG2814	Major facilitator Superfamily
AZ49_RS00415	COG1053	succinate dehydrogenase
AZ49_RS00425	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AZ49_RS00430	COG0805	protein transport
AZ49_RS00445	COG1115	amino acid carrier protein
AZ49_RS00470	COG0688	phosphatidylethanolamine metabolic process
AZ49_RS00480	COG0516	GMP reductase activity
AZ49_RS00480	COG0517	IMP dehydrogenase activity
AZ49_RS00485	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AZ49_RS00490	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AZ49_RS00510	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AZ49_RS00515	COG0517	IMP dehydrogenase activity
AZ49_RS00520	COG0574	Belongs to the PEP-utilizing enzyme family
AZ49_RS00520	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AZ49_RS00525	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AZ49_RS00530	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AZ49_RS00535	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AZ49_RS00540	COG1024	Enoyl-CoA hydratase
AZ49_RS00560	COG1136	(ABC) transporter
AZ49_RS00565	COG0577	efflux transmembrane transporter activity
AZ49_RS00565	COG1136	(ABC) transporter
AZ49_RS00575	COG0436	Aminotransferase
AZ49_RS00580	COG0012	GTP binding
AZ49_RS00590	COG0277	FAD linked oxidase domain protein
AZ49_RS00595	COG0488	(ABC) transporter
AZ49_RS00605	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AZ49_RS00625	COG0671	phosphoesterase, PA-phosphatase related
AZ49_RS00655	COG0571	ribonuclease III activity
AZ49_RS00660	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AZ49_RS00670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AZ49_RS00675	COG1028	Short-chain dehydrogenase reductase Sdr
AZ49_RS00680	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AZ49_RS00685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AZ49_RS00690	COG0416	fatty acid biosynthetic process
AZ49_RS00695	COG2030	dehydratase
AZ49_RS00705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZ49_RS00715	COG4372	Transposase
AZ49_RS00725	COG1137	ATPase activity
AZ49_RS00745	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AZ49_RS00755	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AZ49_RS00760	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AZ49_RS00765	COG1663	tetraacyldisaccharide 4'-kinase activity
AZ49_RS00770	COG1519	Transferase
AZ49_RS00775	COG1132	(ABC) transporter
AZ49_RS00780	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZ49_RS00790	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZ49_RS00795	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AZ49_RS00800	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AZ49_RS00805	COG0165	Argininosuccinate lyase
AZ49_RS00815	COG4499	WXG100 protein secretion system (Wss), protein YukC
AZ49_RS00815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AZ49_RS00825	COG0277	FAD linked oxidase domain protein
AZ49_RS00830	COG3875	lactate racemase activity
AZ49_RS00835	COG1802	Transcriptional regulator
AZ49_RS00840	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AZ49_RS00845	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZ49_RS00850	COG0704	Plays a role in the regulation of phosphate uptake
AZ49_RS00855	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AZ49_RS00860	COG0581	inorganic phosphate transmembrane transporter activity
AZ49_RS00865	COG0573	inorganic phosphate transmembrane transporter activity
AZ49_RS00870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AZ49_RS00875	COG5002	protein histidine kinase activity
AZ49_RS00895	COG1773	rubredoxin
AZ49_RS00895	COG1592	Rubrerythrin
AZ49_RS00900	COG0583	DNA-binding transcription factor activity
AZ49_RS00905	COG0589	response to stress
AZ49_RS00925	COG0101	tRNA pseudouridine synthase activity
AZ49_RS00930	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AZ49_RS00935	COG1122	ATPase activity
AZ49_RS00940	COG1122	ATPase activity
AZ49_RS00995	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AZ49_RS01005	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AZ49_RS01015	COG0037	tRNA processing
AZ49_RS01020	COG0248	Ppx GppA phosphatase
AZ49_RS01025	COG1098	S1 RNA binding domain
AZ49_RS01035	COG0277	FAD linked oxidase domain protein
AZ49_RS01040	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AZ49_RS01040	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AZ49_RS01055	COG1522	sequence-specific DNA binding
AZ49_RS01065	COG2878	Part of a membrane complex involved in electron transport
AZ49_RS01065	COG1148	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZ49_RS01070	COG4657	Part of a membrane complex involved in electron transport
AZ49_RS01075	COG4660	Part of a membrane complex involved in electron transport
AZ49_RS01080	COG4659	FMN binding
AZ49_RS01085	COG4658	electron transport chain
AZ49_RS01090	COG4656	Part of a membrane complex involved in electron transport
AZ49_RS01095	COG0504	CTP synthase activity
AZ49_RS01100	COG0018	arginyl-trna synthetase
AZ49_RS01110	COG1773	rubredoxin
AZ49_RS01110	COG0426	domain, Protein
AZ49_RS01130	COG0589	response to stress
AZ49_RS01155	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AZ49_RS01170	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AZ49_RS01170	COG2080	2 iron, 2 sulfur cluster binding
AZ49_RS01200	COG0004	ammonium transporteR
AZ49_RS01205	COG0084	hydrolase, TatD family'
AZ49_RS01245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZ49_RS01255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZ49_RS01265	COG1481	regulation of sporulation
AZ49_RS01270	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AZ49_RS01280	COG0561	phosphatase activity
AZ49_RS01290	COG3599	regulation of cell shape
AZ49_RS01300	COG1799	cell septum assembly
AZ49_RS01310	COG1496	oxidoreductase activity
AZ49_RS01320	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AZ49_RS01330	COG1450	Type ii and iii secretion system protein
AZ49_RS01340	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AZ49_RS01345	COG0166	Belongs to the GPI family
AZ49_RS01350	COG1126	abc transporter atp-binding protein
AZ49_RS01355	COG0765	amino acid transport
AZ49_RS01360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZ49_RS01385	COG4632	Exopolysaccharide biosynthesis protein
AZ49_RS01385	COG5434	Belongs to the glycosyl hydrolase 28 family
AZ49_RS01405	COG0582	viral genome integration into host DNA
AZ49_RS01455	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AZ49_RS01465	COG0772	Belongs to the SEDS family
AZ49_RS01470	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AZ49_RS01475	COG4948	Mandelate Racemase Muconate Lactonizing
AZ49_RS01485	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AZ49_RS01485	COG0140	phosphoribosyl-ATP diphosphatase activity
AZ49_RS01490	COG0107	imidazoleglycerol-phosphate synthase activity
AZ49_RS01495	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AZ49_RS01500	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AZ49_RS01505	COG0131	Imidazoleglycerol-phosphate dehydratase
AZ49_RS01515	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AZ49_RS01520	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AZ49_RS01525	COG0124	histidyl-tRNA synthetase
AZ49_RS01550	COG1592	Rubrerythrin
AZ49_RS01555	COG0745	RESPONSE REGULATOR receiver
AZ49_RS01560	COG1686	Belongs to the peptidase S11 family
AZ49_RS01570	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AZ49_RS01575	COG2226	methyltransferase
AZ49_RS01605	COG2194	sulfuric ester hydrolase activity
AZ49_RS01610	COG3885	ferrous iron binding
AZ49_RS01610	COG2078	PFAM AMMECR1 domain protein
AZ49_RS01630	COG1823	symporter activity
AZ49_RS01635	COG0159	tryptophan synthase activity
AZ49_RS01640	COG0133	tryptophan synthase activity
AZ49_RS01650	COG0134	indole-3-glycerol-phosphate synthase activity
AZ49_RS01660	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AZ49_RS01660	COG0512	Glutamine amidotransferase of anthranilate synthase
AZ49_RS01670	COG0814	amino acid
AZ49_RS01690	COG0386	Belongs to the glutathione peroxidase family
AZ49_RS01695	COG2033	superoxide reductase activity
AZ49_RS01705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZ49_RS01710	COG0193	aminoacyl-tRNA hydrolase activity
AZ49_RS01720	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AZ49_RS01725	COG1388	LysM domain
AZ49_RS01725	COG3584	3D domain protein
AZ49_RS01735	COG1473	amidohydrolase
AZ49_RS01750	COG0004	ammonium transporteR
AZ49_RS01755	COG0347	Belongs to the P(II) protein family
AZ49_RS01760	COG0710	3-dehydroquinate dehydratase activity
AZ49_RS01765	COG2814	Major facilitator Superfamily
AZ49_RS01770	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AZ49_RS01775	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AZ49_RS01780	COG0077	Prephenate dehydratase
AZ49_RS01780	COG1605	Chorismate mutase
AZ49_RS01785	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AZ49_RS01790	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AZ49_RS01795	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AZ49_RS01805	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AZ49_RS01810	COG0726	polysaccharide deacetylase
AZ49_RS01830	COG1760	l-serine dehydratase
AZ49_RS01835	COG1760	l-serine dehydratase
AZ49_RS01840	COG1074	ATP-dependent DNA helicase activity
AZ49_RS01845	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AZ49_RS01855	COG1414	Transcriptional regulator
AZ49_RS01870	COG1285	pathogenesis
AZ49_RS01880	COG0586	Pfam SNARE associated Golgi protein
AZ49_RS01900	COG0070	glutamate synthase
AZ49_RS01900	COG0069	glutamate synthase activity
AZ49_RS01900	COG0067	glutamate synthase
AZ49_RS01955	COG0385	Bile acid
AZ49_RS01960	COG1573	uracil-dna glycosylase
AZ49_RS01970	COG0385	Bile acid
AZ49_RS01975	COG0129	dihydroxy-acid dehydratase activity
AZ49_RS01980	COG0440	acetolactate synthase activity
AZ49_RS01985	COG0028	Belongs to the TPP enzyme family
AZ49_RS01990	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AZ49_RS02005	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AZ49_RS02010	COG3384	dioxygenase
AZ49_RS02020	COG0420	3'-5' exonuclease activity
AZ49_RS02025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZ49_RS02040	COG2022	thiamine diphosphate biosynthetic process
AZ49_RS02050	COG0352	thiamine-phosphate diphosphorylase activity
AZ49_RS02085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZ49_RS02085	COG2190	(PTS) system
AZ49_RS02085	COG1263	PTS System
AZ49_RS02090	COG1454	alcohol dehydrogenase
AZ49_RS02095	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZ49_RS02100	COG0561	phosphatase activity
AZ49_RS02110	COG1115	amino acid carrier protein
AZ49_RS02120	COG1349	DNA-binding transcription factor activity
AZ49_RS02125	COG2271	Major facilitator Superfamily
AZ49_RS02130	COG2030	dehydratase
AZ49_RS02140	COG2610	gluconate transmembrane transporter activity
AZ49_RS02145	COG0583	DNA-binding transcription factor activity
AZ49_RS02155	COG1028	Short-chain dehydrogenase reductase Sdr
AZ49_RS02175	COG0814	amino acid
AZ49_RS02190	COG0251	oxidation-reduction process
AZ49_RS02210	COG1785	Belongs to the alkaline phosphatase family
AZ49_RS02225	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AZ49_RS02235	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AZ49_RS02240	COG0583	DNA-binding transcription factor activity
AZ49_RS02250	COG2197	response regulator
AZ49_RS02255	COG4585	Histidine kinase
AZ49_RS02265	COG2271	Major facilitator Superfamily
AZ49_RS02270	COG0791	NLP P60 protein
AZ49_RS02270	COG1388	LysM domain
AZ49_RS02315	COG0561	phosphatase activity
AZ49_RS02320	COG0366	Alpha amylase catalytic
AZ49_RS02325	COG1263	PTS System
AZ49_RS02325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZ49_RS02375	COG0084	hydrolase, TatD family'
AZ49_RS02385	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AZ49_RS02390	COG2890	protein-(glutamine-N5) methyltransferase activity
AZ49_RS02395	COG1774	PSP1 C-terminal conserved region
AZ49_RS02400	COG0470	DNA polymerase III
AZ49_RS02405	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AZ49_RS02410	COG1982	Orn Lys Arg decarboxylase major
AZ49_RS02425	COG1268	BioY protein
AZ49_RS02430	COG1716	ATPase activity
AZ49_RS02430	COG5001	Diguanylate cyclase
AZ49_RS02435	COG0222	ribosome binding
AZ49_RS02440	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AZ49_RS02445	COG0081	regulation of translation
AZ49_RS02450	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AZ49_RS02455	COG0250	Participates in transcription elongation, termination and antitermination
AZ49_RS02465	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AZ49_RS02475	COG1027	Aspartate ammonia-lyase
AZ49_RS02485	COG1454	alcohol dehydrogenase
AZ49_RS02490	COG2217	Heavy metal translocating P-type atpase
AZ49_RS02495	COG0531	amino acid
AZ49_RS02500	COG0148	phosphopyruvate hydratase activity
AZ49_RS02525	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AZ49_RS02530	COG0427	acetyl-CoA hydrolase
AZ49_RS02535	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AZ49_RS02540	COG1473	amidohydrolase
AZ49_RS02545	COG1362	aminopeptidase activity
AZ49_RS02550	COG2962	Rard protein
AZ49_RS02565	COG0427	acetyl-CoA hydrolase
AZ49_RS02570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZ49_RS02585	COG0427	acetyl-CoA hydrolase
AZ49_RS02615	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AZ49_RS02620	COG1027	Aspartate ammonia-lyase
AZ49_RS02625	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AZ49_RS02660	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AZ49_RS02670	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AZ49_RS02675	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AZ49_RS02715	COG2033	superoxide reductase activity
AZ49_RS02725	COG1024	Enoyl-CoA hydratase
AZ49_RS02740	COG4670	ketone body catabolic process
AZ49_RS02755	COG2326	polyphosphate kinase activity
AZ49_RS02785	COG2094	Belongs to the DNA glycosylase MPG family
AZ49_RS02790	COG1414	Transcriptional regulator
AZ49_RS02805	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AZ49_RS02810	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AZ49_RS02815	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AZ49_RS02820	COG2885	chlorophyll binding
AZ49_RS02825	COG4187	Peptidase family M20/M25/M40
AZ49_RS02835	COG1846	Transcriptional regulator
AZ49_RS02840	COG2610	gluconate transmembrane transporter activity
AZ49_RS02860	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AZ49_RS02865	COG2207	Transcriptional regulator
AZ49_RS02870	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AZ49_RS02880	COG0473	3-isopropylmalate dehydrogenase activity
AZ49_RS02885	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AZ49_RS02890	COG3527	Alpha-acetolactate decarboxylase
AZ49_RS02895	COG1253	flavin adenine dinucleotide binding
AZ49_RS02905	COG0436	Aminotransferase
AZ49_RS02910	COG0187	DNA topoisomerase II activity
AZ49_RS02925	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AZ49_RS02935	COG0592	DNA-directed DNA polymerase activity
AZ49_RS02940	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AZ49_RS02945	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AZ49_RS02960	COG1847	R3H domain protein
AZ49_RS02965	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AZ49_RS02970	COG0445	tRNA wobble uridine modification
AZ49_RS02975	COG0357	Ribosomal RNA small subunit methyltransferase G
AZ49_RS02990	COG1349	DNA-binding transcription factor activity
AZ49_RS02995	COG1105	Belongs to the carbohydrate kinase PfkB family
AZ49_RS03000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AZ49_RS03000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZ49_RS03000	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AZ49_RS03005	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZ49_RS03035	COG0385	Bile acid
AZ49_RS03040	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AZ49_RS03065	COG0745	RESPONSE REGULATOR receiver
AZ49_RS03070	COG2205	protein histidine kinase activity
AZ49_RS03075	COG2217	Heavy metal translocating P-type atpase
AZ49_RS03080	COG1937	Protein conserved in bacteria
AZ49_RS03090	COG3874	Sporulation protein YtfJ
AZ49_RS03105	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AZ49_RS03115	COG1475	DNA binding
AZ49_RS03125	COG0739	heme binding
AZ49_RS03140	COG2176	DNA-directed DNA polymerase activity
AZ49_RS03145	COG2814	Major facilitator Superfamily
AZ49_RS03155	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZ49_RS03160	COG1312	Catalyzes the dehydration of D-mannonate
AZ49_RS03165	COG2271	Major facilitator Superfamily
AZ49_RS03170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZ49_RS03175	COG0800	Aldolase
AZ49_RS03180	COG1802	Transcriptional regulator
AZ49_RS03185	COG1609	Transcriptional regulator
AZ49_RS03190	COG1904	glucuronate isomerase
AZ49_RS03195	COG0246	Mannitol dehydrogenase
AZ49_RS03200	COG2721	sulfolactate sulfo-lyase activity
AZ49_RS03205	COG2211	Major facilitator Superfamily
AZ49_RS03215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZ49_RS03220	COG0800	Aldolase
AZ49_RS03230	COG1959	2 iron, 2 sulfur cluster binding
AZ49_RS03245	COG1297	OPT oligopeptide transporter protein
AZ49_RS03255	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZ49_RS03270	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AZ49_RS03275	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AZ49_RS03280	COG0360	Binds together with S18 to 16S ribosomal RNA
AZ49_RS03290	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AZ49_RS03295	COG0402	S-adenosylhomocysteine deaminase activity
AZ49_RS03300	COG1597	lipid kinase activity
AZ49_RS03315	COG0306	phosphate transporter
AZ49_RS03325	COG2233	PERMEase
AZ49_RS03330	COG1376	ErfK ybiS ycfS ynhG family protein
AZ49_RS03350	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AZ49_RS03360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AZ49_RS03365	COG2801	Transposase and inactivated derivatives
AZ49_RS03365	COG3415	Transposase
AZ49_RS03370	COG1971	Probably functions as a manganese efflux pump
AZ49_RS03460	COG0549	Belongs to the carbamate kinase family
AZ49_RS03465	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AZ49_RS03470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZ49_RS03485	COG0402	S-adenosylhomocysteine deaminase activity
AZ49_RS03490	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZ49_RS03490	COG0493	'glutamate synthase
AZ49_RS03505	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AZ49_RS03505	COG3608	succinylglutamate desuccinylase aspartoacylase
AZ49_RS03510	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AZ49_RS03515	COG0303	'Molybdopterin
AZ49_RS03525	COG3383	formate dehydrogenase (NAD+) activity
AZ49_RS03530	COG3383	formate dehydrogenase (NAD+) activity
AZ49_RS03535	COG0746	molybdenum cofactor guanylyltransferase activity
AZ49_RS03560	COG0521	Mo-molybdopterin cofactor biosynthetic process
AZ49_RS03565	COG0725	ABC transporter, periplasmic molybdate-binding protein
AZ49_RS03570	COG4149	molybdate abc transporter
AZ49_RS03575	COG3842	ATPase activity
AZ49_RS03585	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AZ49_RS03595	COG0531	amino acid
AZ49_RS03600	COG1943	Transposase
AZ49_RS03605	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AZ49_RS03610	COG3590	peptidase
AZ49_RS03625	COG1151	hydroxylamine reductase activity
AZ49_RS03635	COG2827	Endonuclease containing a URI domain
AZ49_RS03650	COG2390	Transcriptional regulator
AZ49_RS03655	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AZ49_RS03660	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AZ49_RS03665	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AZ49_RS03670	COG3634	alkyl hydroperoxide reductase activity
AZ49_RS03685	COG1045	serine acetyltransferase
AZ49_RS03715	COG0644	oxidoreductase
AZ49_RS03720	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AZ49_RS03730	COG2733	membrane
AZ49_RS03735	COG2733	membrane
AZ49_RS03765	COG0440	acetolactate synthase activity
AZ49_RS03770	COG0028	Belongs to the TPP enzyme family
AZ49_RS03775	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AZ49_RS03780	COG1966	Carbon starvation protein
AZ49_RS03785	COG1966	Carbon starvation protein
AZ49_RS03790	COG0371	Dehydrogenase
AZ49_RS03795	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AZ49_RS03835	COG0280	phosphate acetyltransferase
AZ49_RS03845	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AZ49_RS03850	COG0745	RESPONSE REGULATOR receiver
AZ49_RS03855	COG5002	protein histidine kinase activity
AZ49_RS03865	COG0709	Synthesizes selenophosphate from selenide and ATP
AZ49_RS03870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AZ49_RS03900	COG1921	L-seryl-tRNASec selenium transferase activity
AZ49_RS03925	COG1902	pentaerythritol trinitrate reductase activity
AZ49_RS03925	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZ49_RS03955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZ49_RS03955	COG1263	PTS System
AZ49_RS03960	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AZ49_RS03970	COG0493	'glutamate synthase
AZ49_RS03975	COG0288	reversible hydration of carbon dioxide
AZ49_RS03980	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AZ49_RS04010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AZ49_RS04015	COG1464	Belongs to the NlpA lipoprotein family
AZ49_RS04020	COG2223	nitrite transmembrane transporter activity
AZ49_RS04025	COG0277	FAD linked oxidase domain protein
AZ49_RS04035	COG0477	Major facilitator Superfamily
AZ49_RS04040	COG1473	amidohydrolase
AZ49_RS04050	COG2011	ABC-type metal ion transport system permease component
AZ49_RS04065	COG0803	Belongs to the bacterial solute-binding protein 9 family
AZ49_RS04070	COG1121	(ABC) transporter
AZ49_RS04075	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AZ49_RS04090	COG0640	Transcriptional regulator
AZ49_RS04100	COG0351	phosphomethylpyrimidine kinase
AZ49_RS04100	COG0352	thiamine-phosphate diphosphorylase activity
AZ49_RS04110	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AZ49_RS04120	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AZ49_RS04130	COG1067	ATP-dependent peptidase activity
AZ49_RS04130	COG0470	DNA polymerase III
AZ49_RS04135	COG0305	Participates in initiation and elongation during chromosome replication
AZ49_RS04170	COG0668	transmembrane transport
AZ49_RS04175	COG1620	l-lactate permease
AZ49_RS04180	COG4670	ketone body catabolic process
AZ49_RS04230	COG2217	Heavy metal translocating P-type atpase
AZ49_RS04235	COG2271	Major facilitator Superfamily
AZ49_RS04270	COG1573	uracil-dna glycosylase
AZ49_RS04275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZ49_RS04290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AZ49_RS04295	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
AZ49_RS04300	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AZ49_RS04305	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AZ49_RS04310	COG0085	RNA polymerase activity
AZ49_RS04315	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AZ49_RS04330	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AZ49_RS04335	COG0049	tRNA binding
AZ49_RS04340	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AZ49_RS04345	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AZ49_RS04355	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AZ49_RS04360	COG0088	Forms part of the polypeptide exit tunnel
AZ49_RS04375	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AZ49_RS04380	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AZ49_RS04385	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AZ49_RS04390	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AZ49_RS04395	COG0255	Belongs to the universal ribosomal protein uL29 family
AZ49_RS04400	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AZ49_RS04405	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AZ49_RS04410	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AZ49_RS04420	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AZ49_RS04425	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AZ49_RS04430	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AZ49_RS04435	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AZ49_RS04440	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AZ49_RS04445	COG1841	ribosomal large subunit assembly
AZ49_RS04450	COG0200	Binds to the 23S rRNA
AZ49_RS04455	COG0201	protein transport
AZ49_RS04460	COG0563	adenylate kinase activity
AZ49_RS04480	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AZ49_RS04485	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AZ49_RS04495	COG0202	RNA polymerase activity
AZ49_RS04500	COG0203	ribosomal protein L17
AZ49_RS04520	COG4464	protein tyrosine phosphatase activity
AZ49_RS04535	COG0489	protein tyrosine kinase activity
AZ49_RS04540	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AZ49_RS04545	COG0438	transferase activity, transferring glycosyl groups
AZ49_RS04565	COG1216	Glycosyl transferase, family 2
AZ49_RS04570	COG1442	glycosyl transferase family 8
AZ49_RS04570	COG1216	Glycosyl transferase, family 2
AZ49_RS04575	COG1216	Glycosyl transferase, family 2
AZ49_RS04605	COG2003	Belongs to the UPF0758 family
AZ49_RS04615	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AZ49_RS04660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZ49_RS04665	COG0284	orotidine-5'-phosphate decarboxylase activity
AZ49_RS04670	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AZ49_RS04690	COG0540	Belongs to the ATCase OTCase family
AZ49_RS04700	COG0505	Belongs to the CarA family
AZ49_RS04705	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AZ49_RS04720	COG1619	proteins homologs of microcin C7 resistance protein MccF
AZ49_RS04725	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AZ49_RS04735	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AZ49_RS04740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AZ49_RS04755	COG1982	Orn Lys Arg decarboxylase major
AZ49_RS04760	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AZ49_RS04765	COG1464	Belongs to the NlpA lipoprotein family
AZ49_RS04770	COG1464	Belongs to the NlpA lipoprotein family
AZ49_RS04785	COG1122	ATPase activity
AZ49_RS04800	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AZ49_RS04820	COG0126	phosphoglycerate kinase activity
AZ49_RS04825	COG0149	triose-phosphate isomerase activity
AZ49_RS04840	COG1063	alcohol dehydrogenase
AZ49_RS04855	COG3279	Response regulator of the LytR AlgR family
AZ49_RS04860	COG3711	transcriptional antiterminator
AZ49_RS04860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZ49_RS04865	COG1392	Phosphate transport regulator
AZ49_RS04870	COG0306	phosphate transporter
AZ49_RS04875	COG1959	2 iron, 2 sulfur cluster binding
AZ49_RS04880	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AZ49_RS04890	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AZ49_RS04900	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AZ49_RS04910	COG0280	phosphate acetyltransferase
AZ49_RS04925	COG0280	phosphate acetyltransferase
AZ49_RS04950	COG3850	Histidine kinase
AZ49_RS04950	COG5002	protein histidine kinase activity
AZ49_RS04955	COG0745	RESPONSE REGULATOR receiver
AZ49_RS04965	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AZ49_RS04970	COG0564	pseudouridine synthase activity
AZ49_RS04975	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AZ49_RS04980	COG2376	Dihydroxyacetone kinase
AZ49_RS04990	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AZ49_RS04995	COG1073	alpha beta
AZ49_RS05000	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZ49_RS05010	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AZ49_RS05015	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZ49_RS05020	COG0406	alpha-ribazole phosphatase activity
AZ49_RS05025	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AZ49_RS05030	COG1494	fructose-1,6-bisphosphatase
AZ49_RS05035	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AZ49_RS05040	COG1077	Cell shape determining protein MreB Mrl
AZ49_RS05050	COG0750	zinc metalloprotease
AZ49_RS05055	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AZ49_RS05060	COG1127	ABC transporter
AZ49_RS05080	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZ49_RS05095	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AZ49_RS05120	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZ49_RS05135	COG3853	Toxic anion resistance protein (TelA)
AZ49_RS05155	COG1674	ftsk spoiiie
AZ49_RS05175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZ49_RS05180	COG1058	Belongs to the CinA family
AZ49_RS05180	COG1546	Belongs to the CinA family
AZ49_RS05185	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AZ49_RS05190	COG2137	regulation of response to DNA damage stimulus
AZ49_RS05195	COG1418	mRNA catabolic process
AZ49_RS05225	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AZ49_RS05230	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AZ49_RS05235	COG1187	pseudouridine synthase activity
AZ49_RS05240	COG2081	HI0933 family
AZ49_RS05245	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AZ49_RS05250	COG0204	Acyl-transferase
AZ49_RS05255	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AZ49_RS05255	COG0539	negative regulation of cytoplasmic translation
AZ49_RS05260	COG1160	GTP binding
AZ49_RS05265	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AZ49_RS05270	COG0742	ribosomal rna small subunit methyltransferase
AZ49_RS05275	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AZ49_RS05285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AZ49_RS05290	COG1691	(AIR) carboxylase
AZ49_RS05295	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AZ49_RS05300	COG3394	polysaccharide catabolic process
AZ49_RS05305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZ49_RS05310	COG4492	Belongs to the UPF0735 family
AZ49_RS05315	COG0460	homoserine dehydrogenase
AZ49_RS05320	COG0083	homoserine kinase activity
AZ49_RS05330	COG0525	valine-tRNA ligase activity
AZ49_RS05345	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AZ49_RS05350	COG2357	RelA SpoT domain protein
AZ49_RS05355	COG0745	RESPONSE REGULATOR receiver
AZ49_RS05360	COG5002	protein histidine kinase activity
AZ49_RS05365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AZ49_RS05385	COG2264	protein methyltransferase activity
AZ49_RS05410	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AZ49_RS05415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AZ49_RS05420	COG2814	Major facilitator Superfamily
AZ49_RS05425	COG1473	amidohydrolase
AZ49_RS05435	COG0617	tRNA 3'-terminal CCA addition
AZ49_RS05440	COG0768	penicillin binding
AZ49_RS05445	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AZ49_RS05450	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AZ49_RS05455	COG1013	pyruvate-flavodoxin oxidoreductase activity
AZ49_RS05455	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AZ49_RS05455	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZ49_RS05455	COG0674	pyruvate-flavodoxin oxidoreductase activity
AZ49_RS05465	COG0406	alpha-ribazole phosphatase activity
AZ49_RS05485	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AZ49_RS05510	COG0521	Mo-molybdopterin cofactor biosynthetic process
AZ49_RS05520	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AZ49_RS05530	COG1187	pseudouridine synthase activity
AZ49_RS05540	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AZ49_RS05560	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AZ49_RS05565	COG1570	exodeoxyribonuclease VII activity
AZ49_RS05580	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AZ49_RS05585	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AZ49_RS05595	COG1438	arginine binding
AZ49_RS05600	COG0497	DNA recombination
AZ49_RS05605	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AZ49_RS05610	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AZ49_RS05615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZ49_RS05645	COG0531	amino acid
AZ49_RS05650	COG0183	Belongs to the thiolase family
AZ49_RS05655	COG0183	Belongs to the thiolase family
AZ49_RS05680	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AZ49_RS05685	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AZ49_RS05690	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AZ49_RS05695	COG2223	nitrite transmembrane transporter activity
AZ49_RS05700	COG0436	Aminotransferase
AZ49_RS05715	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AZ49_RS05720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZ49_RS05725	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AZ49_RS05740	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AZ49_RS05745	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AZ49_RS05755	COG1837	Belongs to the UPF0109 family
AZ49_RS05765	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AZ49_RS05770	COG0336	Belongs to the RNA methyltransferase TrmD family
AZ49_RS05775	COG4752	Belongs to the RNA methyltransferase TrmD family
AZ49_RS05780	COG0217	transcriptional regulatory protein
AZ49_RS05905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AZ49_RS05915	COG0511	ligase activity, forming carbon-carbon bonds
AZ49_RS05925	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AZ49_RS05960	COG0028	Belongs to the TPP enzyme family
AZ49_RS05965	COG1683	Conserved Protein
AZ49_RS05970	COG0681	Belongs to the peptidase S26 family
AZ49_RS05980	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AZ49_RS06005	COG0302	gtp cyclohydrolase
AZ49_RS06010	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AZ49_RS06015	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AZ49_RS06020	COG0745	RESPONSE REGULATOR receiver
AZ49_RS06045	COG0813	purine-nucleoside phosphorylase activity
AZ49_RS06060	COG0602	queuosine metabolic process
AZ49_RS06085	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZ49_RS06095	COG0275	rRNA processing
AZ49_RS06100	COG4839	cell division protein FtsL
AZ49_RS06105	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AZ49_RS06110	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AZ49_RS06115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AZ49_RS06120	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AZ49_RS06125	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AZ49_RS06130	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AZ49_RS06140	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AZ49_RS06145	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AZ49_RS06150	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AZ49_RS06155	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AZ49_RS06155	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AZ49_RS06160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZ49_RS06175	COG0859	PFAM glycosyl transferase family 9
AZ49_RS06185	COG2050	protein possibly involved in aromatic compounds catabolism
AZ49_RS06195	COG1960	acyl-CoA dehydrogenase activity
AZ49_RS06200	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AZ49_RS06205	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZ49_RS06205	COG0072	phenylalanine-tRNA ligase activity
AZ49_RS06210	COG0544	peptidyl-prolyl cis-trans isomerase activity
AZ49_RS06215	COG0740	serine-type endopeptidase activity
AZ49_RS06220	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AZ49_RS06225	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AZ49_RS06230	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AZ49_RS06240	COG0463	Glycosyl transferase, family 2
AZ49_RS06245	COG0791	NLP P60 protein
AZ49_RS06250	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AZ49_RS06255	COG4472	Bacterial protein of unknown function (DUF965)
AZ49_RS06260	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AZ49_RS06265	COG3906	Belongs to the UPF0473 family
AZ49_RS06270	COG0583	DNA-binding transcription factor activity
AZ49_RS06290	COG0789	Transcriptional regulator
AZ49_RS06310	COG3959	Transketolase, thiamine diphosphate binding domain
AZ49_RS06315	COG3958	Transketolase
AZ49_RS06320	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AZ49_RS06330	COG1606	tRNA processing
AZ49_RS06335	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AZ49_RS06340	COG1114	Component of the transport system for branched-chain amino acids
AZ49_RS06345	COG1012	belongs to the aldehyde dehydrogenase family
AZ49_RS06350	COG0281	malic enzyme
AZ49_RS06355	COG0584	glycerophosphoryl diester phosphodiesterase
AZ49_RS06360	COG1115	amino acid carrier protein
AZ49_RS06365	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AZ49_RS06375	COG0157	Belongs to the NadC ModD family
AZ49_RS06405	COG0556	nucleotide-excision repair
AZ49_RS06410	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AZ49_RS06415	COG0322	excinuclease ABC activity
AZ49_RS06445	COG0396	ATPase activity
AZ49_RS06460	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AZ49_RS06465	COG0822	iron-sulfur transferase activity
AZ49_RS06470	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AZ49_RS06480	COG0495	leucyl-tRNA aminoacylation
AZ49_RS06505	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AZ49_RS06515	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AZ49_RS06525	COG1196	nuclear chromosome segregation
AZ49_RS06530	COG0552	protein localization to endoplasmic reticulum
AZ49_RS06540	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AZ49_RS06550	COG1309	transcriptional regulator
AZ49_RS06555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZ49_RS06565	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AZ49_RS06565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZ49_RS06575	COG1242	4 iron, 4 sulfur cluster binding
AZ49_RS06580	COG1702	phosphate starvation-inducible protein PhoH
AZ49_RS06595	COG1253	flavin adenine dinucleotide binding
AZ49_RS06615	COG0534	Mate efflux family protein
AZ49_RS06625	COG5002	protein histidine kinase activity
AZ49_RS06630	COG0745	RESPONSE REGULATOR receiver
AZ49_RS06645	COG2384	SAM-dependent methyltransferase
AZ49_RS06650	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AZ49_RS06655	COG0352	thiamine-phosphate diphosphorylase activity
AZ49_RS06675	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AZ49_RS06675	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AZ49_RS06680	COG2333	competence protein COMEC
AZ49_RS06680	COG0658	competence protein
AZ49_RS06705	COG3206	protein involved in exopolysaccharide biosynthesis
AZ49_RS06710	COG3206	protein involved in exopolysaccharide biosynthesis
AZ49_RS06715	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AZ49_RS06720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AZ49_RS06725	COG0653	protein targeting
AZ49_RS06730	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AZ49_RS06750	COG2884	Cell division ATP-binding protein ftsE
AZ49_RS06755	COG2177	Part of the ABC transporter FtsEX involved in
AZ49_RS06760	COG4942	peptidase
AZ49_RS06765	COG0793	Belongs to the peptidase S41A family
AZ49_RS06770	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AZ49_RS06780	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AZ49_RS06785	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AZ49_RS06795	COG1713	HD superfamily hydrolase involved in NAD metabolism
AZ49_RS06805	COG0799	negative regulation of ribosome biogenesis
AZ49_RS06810	COG2996	Protein conserved in bacteria
AZ49_RS06830	COG0517	IMP dehydrogenase activity
AZ49_RS06830	COG0617	tRNA 3'-terminal CCA addition
AZ49_RS06830	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AZ49_RS06840	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AZ49_RS06860	COG1196	nuclear chromosome segregation
AZ49_RS06870	COG0786	glutamate:sodium symporter activity
AZ49_RS06875	COG1323	Belongs to the UPF0348 family
AZ49_RS06900	COG0583	DNA-binding transcription factor activity
AZ49_RS06910	COG0697	spore germination
AZ49_RS06915	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AZ49_RS06915	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AZ49_RS06920	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AZ49_RS06925	COG1490	D-aminoacyl-tRNA deacylase activity
AZ49_RS06930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZ49_RS06935	COG0628	permease
AZ49_RS06940	COG0735	belongs to the Fur family
AZ49_RS06945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AZ49_RS06950	COG0124	histidyl-tRNA synthetase
AZ49_RS06955	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AZ49_RS06975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AZ49_RS07015	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AZ49_RS07020	COG1185	polyribonucleotide nucleotidyltransferase activity
AZ49_RS07025	COG0756	dUTP diphosphatase activity
AZ49_RS07030	COG0494	nUDIX hydrolase
AZ49_RS07035	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AZ49_RS07045	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AZ49_RS07050	COG2832	Protein of unknown function (DUF454)
AZ49_RS07055	COG4626	Terminase
AZ49_RS07055	COG1802	Transcriptional regulator
AZ49_RS07065	COG4695	Portal protein
AZ49_RS07100	COG0640	Transcriptional regulator
AZ49_RS07110	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AZ49_RS07155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AZ49_RS07165	COG2116	formate transmembrane transporter activity
AZ49_RS07170	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AZ49_RS07185	COG3437	response regulator, receiver
AZ49_RS07240	COG2086	electron transfer activity
AZ49_RS07245	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AZ49_RS07260	COG3191	aminopeptidase activity
AZ49_RS07265	COG0562	UDP-galactopyranose mutase
AZ49_RS07270	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AZ49_RS07275	COG0590	tRNA wobble adenosine to inosine editing
AZ49_RS07280	COG2860	membrane
AZ49_RS07290	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AZ49_RS07300	COG0826	peptidase U32
AZ49_RS07315	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AZ49_RS07320	COG0058	SHG alpha-glucan phosphorylase activity
AZ49_RS07325	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AZ49_RS07330	COG0297	glycogen (starch) synthase activity
AZ49_RS07345	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AZ49_RS07350	COG1104	cysteine desulfurase activity
AZ49_RS07355	COG0482	sulfurtransferase activity
AZ49_RS07360	COG0481	GTPase activity
AZ49_RS07365	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AZ49_RS07375	COG0174	glutamine synthetase
AZ49_RS07385	COG0708	Exodeoxyribonuclease III
AZ49_RS07390	COG0033	Phosphoglucomutase
AZ49_RS07395	COG3830	Belongs to the UPF0237 family
AZ49_RS07400	COG2848	UPF0210 protein
AZ49_RS07405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AZ49_RS07410	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AZ49_RS07425	COG0356	it plays a direct role in the translocation of protons across the membrane
AZ49_RS07430	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AZ49_RS07435	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AZ49_RS07440	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AZ49_RS07445	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AZ49_RS07450	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AZ49_RS07460	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AZ49_RS07465	COG0752	glycyl-tRNA synthetase alpha subunit
AZ49_RS07480	COG0335	large ribosomal subunit rRNA binding
AZ49_RS07485	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AZ49_RS07490	COG1227	inorganic diphosphatase activity
AZ49_RS07495	COG0210	DNA helicase
AZ49_RS07500	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AZ49_RS07505	COG3328	transposase activity
AZ49_RS07520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AZ49_RS07550	COG1192	Involved in chromosome partitioning
AZ49_RS07595	COG0613	PHP domain protein
AZ49_RS07615	COG1196	nuclear chromosome segregation
AZ49_RS07645	COG1088	dTDP-glucose 4,6-dehydratase activity
AZ49_RS07650	COG1091	dTDP-4-dehydrorhamnose reductase activity
AZ49_RS07695	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AZ49_RS07705	COG0765	amino acid transport
AZ49_RS07715	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AZ49_RS07720	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AZ49_RS07725	COG0113	porphobilinogen synthase activity
AZ49_RS07750	COG1070	Carbohydrate kinase
AZ49_RS07755	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AZ49_RS07760	COG2610	gluconate transmembrane transporter activity
AZ49_RS07770	COG0543	2 iron, 2 sulfur cluster binding
AZ49_RS07775	COG0167	dihydroorotate dehydrogenase activity
AZ49_RS07780	COG2011	ABC-type metal ion transport system permease component
AZ49_RS07785	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AZ49_RS07790	COG2309	aminopeptidase activity
AZ49_RS07795	COG0534	Mate efflux family protein
AZ49_RS07800	COG0268	Binds directly to 16S ribosomal RNA
AZ49_RS07805	COG0191	fructose-bisphosphate aldolase activity
AZ49_RS07810	COG0564	pseudouridine synthase activity
AZ49_RS07815	COG0358	DNA primase activity
AZ49_RS07820	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZ49_RS07835	COG1410	methionine synthase
AZ49_RS07835	COG0646	methionine synthase
AZ49_RS07845	COG0004	ammonium transporteR
AZ49_RS07855	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AZ49_RS07860	COG1959	2 iron, 2 sulfur cluster binding
AZ49_RS07875	COG0561	phosphatase activity
AZ49_RS07885	COG3959	Transketolase, thiamine diphosphate binding domain
AZ49_RS07890	COG3958	Transketolase
AZ49_RS07905	COG3404	Formiminotransferase-cyclodeaminase
AZ49_RS07910	COG1994	Peptidase M50
AZ49_RS07925	COG1492	cobalamin metabolic process
AZ49_RS07930	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AZ49_RS07935	COG0083	homoserine kinase activity
AZ49_RS07945	COG1114	Component of the transport system for branched-chain amino acids
AZ49_RS07950	COG0531	amino acid
AZ49_RS07955	COG0179	Fumarylacetoacetate (FAA) hydrolase
AZ49_RS07970	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AZ49_RS07975	COG0613	PHP domain protein
AZ49_RS07985	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AZ49_RS07990	COG2244	polysaccharide biosynthetic process
AZ49_RS08050	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AZ49_RS08055	COG3584	3D domain protein
AZ49_RS08055	COG1388	LysM domain
AZ49_RS08060	COG0052	Belongs to the universal ribosomal protein uS2 family
AZ49_RS08065	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AZ49_RS08070	COG0528	UMP kinase activity
AZ49_RS08075	COG0233	cytoplasmic translational termination
AZ49_RS08085	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AZ49_RS08090	COG4589	Belongs to the CDS family
AZ49_RS08095	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AZ49_RS08100	COG0750	zinc metalloprotease
AZ49_RS08110	COG0442	prolyl-tRNA aminoacylation
AZ49_RS08115	COG1846	Transcriptional regulator
AZ49_RS08125	COG3956	TIGRFAM MazG family protein
AZ49_RS08130	COG0776	regulation of translation
AZ49_RS08135	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AZ49_RS08145	COG1028	Short-chain dehydrogenase reductase Sdr
AZ49_RS08165	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AZ49_RS08180	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AZ49_RS08190	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AZ49_RS08200	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AZ49_RS08205	COG1561	YicC-like family, N-terminal region
AZ49_RS08210	COG2052	Domain of unknown function (DUF370)
AZ49_RS08215	COG0194	GDP metabolic process
AZ49_RS08225	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AZ49_RS08240	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AZ49_RS08245	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AZ49_RS08250	COG0242	peptide deformylase activity
AZ49_RS08255	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AZ49_RS08260	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AZ49_RS08260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZ49_RS08265	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AZ49_RS08270	COG0631	protein serine/threonine phosphatase activity
AZ49_RS08275	COG2815	serine threonine protein kinase
AZ49_RS08275	COG0515	serine threonine protein kinase
AZ49_RS08280	COG1162	GTPase activity
AZ49_RS08285	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AZ49_RS08300	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AZ49_RS08305	COG0463	Glycosyl transferase, family 2
AZ49_RS08320	COG1216	Glycosyl transferase, family 2
AZ49_RS08335	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AZ49_RS08340	COG2194	sulfuric ester hydrolase activity
AZ49_RS08355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AZ49_RS08365	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AZ49_RS08370	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AZ49_RS08375	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AZ49_RS08380	COG0402	S-adenosylhomocysteine deaminase activity
AZ49_RS08405	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AZ49_RS08430	COG1196	nuclear chromosome segregation
AZ49_RS08460	COG1966	Carbon starvation protein
AZ49_RS08470	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AZ49_RS08480	COG4208	sulfate ABC transporter
AZ49_RS08485	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AZ49_RS08490	COG1053	succinate dehydrogenase
AZ49_RS08500	COG0175	sulfate reduction
AZ49_RS08540	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AZ49_RS08585	COG1970	mechanosensitive ion channel activity
AZ49_RS08615	COG2801	Transposase and inactivated derivatives
AZ49_RS08665	COG0175	sulfate reduction
AZ49_RS08760	COG1783	phage Terminase large subunit
AZ49_RS08865	COG4974	Belongs to the 'phage' integrase family
AZ49_RS08945	COG0741	lytic transglycosylase activity
AZ49_RS08990	COG0500	methyltransferase
AZ49_RS09015	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AZ49_RS09020	COG2367	Beta-lactamase
AZ49_RS09025	COG2801	Transposase and inactivated derivatives
AZ49_RS09095	COG0629	single-stranded DNA binding
AZ49_RS09110	COG2003	Belongs to the UPF0758 family
AZ49_RS09120	COG1388	LysM domain
AZ49_RS09135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AZ49_RS09190	COG1301	dicarboxylic acid transport
AZ49_RS09205	COG3451	type IV secretory pathway VirB4
AZ49_RS09220	COG4962	Type ii secretion system protein e
AZ49_RS09255	COG2814	Major facilitator Superfamily
AZ49_RS09275	COG4221	oxidoreductase activity
AZ49_RS09285	COG0582	viral genome integration into host DNA
AZ49_RS09325	COG0622	Phosphoesterase
AZ49_RS09330	COG1902	pentaerythritol trinitrate reductase activity
AZ49_RS09335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZ49_RS09355	COG0861	Integral membrane protein TerC family
AZ49_RS09360	COG2084	Dehydrogenase
AZ49_RS09400	COG2814	Major facilitator Superfamily
AZ49_RS09405	COG1070	Carbohydrate kinase
AZ49_RS09475	COG0656	L-ascorbic acid biosynthetic process
AZ49_RS09485	COG0583	DNA-binding transcription factor activity
AZ49_RS09505	COG0114	fumarate hydratase activity
AZ49_RS09515	COG0151	Belongs to the GarS family
AZ49_RS09520	COG0138	bifunctional purine biosynthesis protein purh
AZ49_RS09525	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AZ49_RS09530	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AZ49_RS09535	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AZ49_RS09540	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AZ49_RS09560	COG0583	DNA-binding transcription factor activity
AZ49_RS09600	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AZ49_RS09655	COG1040	competence protein
AZ49_RS09660	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AZ49_RS09670	COG0833	amino acid
AZ49_RS09680	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AZ49_RS09690	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AZ49_RS09695	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AZ49_RS09700	COG1177	transmembrane transport
AZ49_RS09710	COG3842	ATPase activity
AZ49_RS09715	COG0741	lytic transglycosylase activity
AZ49_RS09725	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AZ49_RS09730	COG2252	PERMEase
AZ49_RS09755	COG0248	Ppx GppA phosphatase
AZ49_RS09765	COG2003	Belongs to the UPF0758 family
AZ49_RS09770	COG0424	maF-like protein
AZ49_RS09780	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZ49_RS09795	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AZ49_RS09800	COG0154	amidase activity
AZ49_RS09815	COG1797	cobyrinic acid a,c-diamide synthase activity
AZ49_RS09845	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
AZ49_RS09850	COG1120	ATPase activity
AZ49_RS09855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZ49_RS09865	COG4206	TonB-dependent receptor
AZ49_RS09870	COG0848	biopolymer transport protein
AZ49_RS09875	COG0811	peptide transport
AZ49_RS09920	COG1459	type II secretion system
AZ49_RS09940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AZ49_RS09960	COG2203	Gaf domain
AZ49_RS09960	COG2199	diguanylate cyclase activity
AZ49_RS09965	COG1530	ribonuclease E activity
AZ49_RS09985	COG0772	Belongs to the SEDS family
AZ49_RS09990	COG2894	cell division
AZ49_RS09995	COG0768	penicillin binding
AZ49_RS10005	COG1792	Involved in formation and maintenance of cell shape
AZ49_RS10010	COG1077	Cell shape determining protein MreB Mrl
AZ49_RS10035	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AZ49_RS10040	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AZ49_RS10045	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AZ49_RS10050	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AZ49_RS10055	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AZ49_RS10065	COG0066	3-isopropylmalate dehydratase activity
AZ49_RS10070	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AZ49_RS10075	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZ49_RS10080	COG0513	Belongs to the DEAD box helicase family
AZ49_RS10085	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AZ49_RS10095	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AZ49_RS10100	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AZ49_RS10110	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AZ49_RS10115	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AZ49_RS10120	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZ49_RS10155	COG3415	Transposase
AZ49_RS10155	COG2801	Transposase and inactivated derivatives
AZ49_RS10170	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZ49_RS10190	COG1217	gtp-binding protein TYPA
AZ49_RS10200	COG3681	Belongs to the UPF0597 family
AZ49_RS10215	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AZ49_RS10225	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AZ49_RS10240	COG0726	polysaccharide deacetylase
AZ49_RS10250	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AZ49_RS10265	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZ49_RS10270	COG3206	protein involved in exopolysaccharide biosynthesis
AZ49_RS10280	COG0488	(ABC) transporter
AZ49_RS10285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AZ49_RS10290	COG2244	polysaccharide biosynthetic process
AZ49_RS10295	COG0436	Aminotransferase
AZ49_RS10300	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AZ49_RS10320	COG0823	Involved in the tonB-independent uptake of proteins
AZ49_RS10320	COG1506	peptidase
AZ49_RS10320	COG4946	Tricorn protease homolog
AZ49_RS10330	COG1918	ferrous iron import across plasma membrane
AZ49_RS10330	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AZ49_RS10365	COG0515	serine threonine protein kinase
AZ49_RS10370	COG0758	DNA mediated transformation
AZ49_RS10380	COG0792	nuclease activity
AZ49_RS10385	COG0537	adenosine 5'-monophosphoramidase activity
AZ49_RS10390	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZ49_RS10395	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AZ49_RS10400	COG2264	protein methyltransferase activity
AZ49_RS10405	COG0484	heat shock protein binding
AZ49_RS10415	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AZ49_RS10420	COG1420	regulation of RNA biosynthetic process
AZ49_RS10430	COG1024	Enoyl-CoA hydratase
AZ49_RS10435	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZ49_RS10445	COG1070	Carbohydrate kinase
AZ49_RS10455	COG4496	protein, YerC YecD
AZ49_RS10460	COG2176	DNA-directed DNA polymerase activity
AZ49_RS10470	COG2720	vancomycin resistance protein
AZ49_RS10490	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AZ49_RS10535	COG0582	viral genome integration into host DNA
AZ49_RS10540	COG1362	aminopeptidase activity
AZ49_RS10550	COG1739	Uncharacterized protein family UPF0029
AZ49_RS10555	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZ49_RS10560	COG1113	amino acid transport
AZ49_RS10590	COG0310	cobalt ion transport
AZ49_RS10600	COG1122	ATPase activity
AZ49_RS10645	COG1278	Cold shock
AZ49_RS10650	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AZ49_RS10655	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AZ49_RS10660	COG0514	ATP-dependent DNA helicase (RecQ)
AZ49_RS10665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZ49_RS10670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZ49_RS10675	COG0196	riboflavin kinase activity
AZ49_RS10680	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AZ49_RS10690	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AZ49_RS10695	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AZ49_RS10705	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AZ49_RS10710	COG0195	Participates in both transcription termination and antitermination
AZ49_RS10715	COG0779	Required for maturation of 30S ribosomal subunits
AZ49_RS10735	COG0237	dephospho-CoA kinase activity
AZ49_RS10740	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AZ49_RS10745	COG0463	Glycosyl transferase, family 2
AZ49_RS10775	COG2855	membrane
AZ49_RS10780	COG2040	homocysteine
AZ49_RS10785	COG1115	amino acid carrier protein
AZ49_RS10795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AZ49_RS10805	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AZ49_RS10825	COG0557	exoribonuclease II activity
AZ49_RS10830	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AZ49_RS10840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AZ49_RS10850	COG0215	cysteine-tRNA ligase activity
AZ49_RS10855	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZ49_RS10860	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AZ49_RS10860	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AZ49_RS10865	COG4956	integral membrane protein (PIN domain superfamily)
AZ49_RS10880	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AZ49_RS10895	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AZ49_RS10900	COG0542	response to heat
AZ49_RS10905	COG3869	Catalyzes the specific phosphorylation of arginine residues in
AZ49_RS10910	COG3880	PFAM UvrB UvrC protein
AZ49_RS10915	COG4463	regulation of RNA biosynthetic process
AZ49_RS10920	COG1132	(ABC) transporter
AZ49_RS10925	COG5265	(ABC) transporter
AZ49_RS10945	COG0328	RNA-DNA hybrid ribonuclease activity
AZ49_RS10955	COG1234	tRNA 3'-trailer cleavage
AZ49_RS10965	COG1929	Belongs to the glycerate kinase type-1 family
AZ49_RS10970	COG3835	regulator
AZ49_RS10975	COG1733	regulation of RNA biosynthetic process
AZ49_RS10995	COG1114	Component of the transport system for branched-chain amino acids
AZ49_RS11000	COG1686	Belongs to the peptidase S11 family
AZ49_RS11035	COG0242	peptide deformylase activity
AZ49_RS11050	COG3579	cysteine-type endopeptidase activity
AZ49_RS11055	COG2195	Cleaves the N-terminal amino acid of tripeptides
AZ49_RS11070	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AZ49_RS11105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AZ49_RS11110	COG1733	regulation of RNA biosynthetic process
AZ49_RS11140	COG0778	Nitroreductase
AZ49_RS11175	COG5001	Diguanylate cyclase
AZ49_RS11175	COG4251	negative regulation of phosphorylation
AZ49_RS11175	COG3706	GGDEF domain
AZ49_RS11175	COG2203	Gaf domain
AZ49_RS11185	COG0679	Auxin Efflux Carrier
AZ49_RS11205	COG2226	methyltransferase
AZ49_RS11250	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AZ49_RS11250	COG0519	Catalyzes the synthesis of GMP from XMP
AZ49_RS11255	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AZ49_RS11255	COG0617	tRNA 3'-terminal CCA addition
AZ49_RS11255	COG0517	IMP dehydrogenase activity
AZ49_RS11265	COG0251	oxidation-reduction process
AZ49_RS11270	COG1113	amino acid transport
AZ49_RS11275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AZ49_RS11300	COG0459	protein refolding
AZ49_RS11325	COG0456	acetyltransferase
AZ49_RS11330	COG1214	PFAM Peptidase M22, glycoprotease
AZ49_RS11335	COG0802	atpase or kinase
AZ49_RS11340	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AZ49_RS11385	COG0477	Major facilitator Superfamily
AZ49_RS11390	COG1827	regulation of RNA biosynthetic process
AZ49_RS11405	COG0583	DNA-binding transcription factor activity
AZ49_RS11420	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AZ49_RS11425	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AZ49_RS11430	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AZ49_RS11440	COG0343	queuine tRNA-ribosyltransferase activity
AZ49_RS11445	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AZ49_RS11450	COG2247	cell wall binding repeat
AZ49_RS11450	COG2385	sporulation resulting in formation of a cellular spore
AZ49_RS11460	COG2255	four-way junction helicase activity
AZ49_RS11465	COG0632	four-way junction helicase activity
AZ49_RS11470	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AZ49_RS11485	COG0668	transmembrane transport
AZ49_RS11495	COG0583	DNA-binding transcription factor activity
AZ49_RS11540	COG3344	reverse transcriptase
AZ49_RS11555	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AZ49_RS11575	COG1979	alcohol dehydrogenase
AZ49_RS11580	COG0583	DNA-binding transcription factor activity
AZ49_RS11585	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AZ49_RS11595	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AZ49_RS11610	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AZ49_RS11630	COG2911	Protein conserved in bacteria
AZ49_RS11630	COG1361	Conserved repeat domain
AZ49_RS11630	COG3266	domain, Protein
AZ49_RS11635	COG0252	asparaginase activity
AZ49_RS11640	COG0531	amino acid
AZ49_RS11655	COG4864	UPF0365 protein
AZ49_RS11660	COG1030	water channel activity
AZ49_RS11670	COG1454	alcohol dehydrogenase
AZ49_RS11680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AZ49_RS11685	COG0180	Tryptophanyl-tRNA synthetase