locus-tag	class	description
DKB62_RS00015	COG0826	peptidase U32
DKB62_RS00025	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DKB62_RS00030	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DKB62_RS00035	COG0058	SHG alpha-glucan phosphorylase activity
DKB62_RS00040	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DKB62_RS00045	COG0297	glycogen (starch) synthase activity
DKB62_RS00050	COG1640	4-alpha-glucanotransferase
DKB62_RS00055	COG0281	malic enzyme
DKB62_RS00060	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DKB62_RS00065	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DKB62_RS00075	COG0717	Belongs to the dCTP deaminase family
DKB62_RS00090	COG0863	Belongs to the N(4) N(6)-methyltransferase family
DKB62_RS00095	COG3191	aminopeptidase activity
DKB62_RS00100	COG2076	Multidrug Resistance protein
DKB62_RS00105	COG2076	Multidrug Resistance protein
DKB62_RS00110	COG4978	Transcriptional regulator
DKB62_RS00110	COG0789	Transcriptional regulator
DKB62_RS00130	COG1902	pentaerythritol trinitrate reductase activity
DKB62_RS00135	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DKB62_RS00140	COG1492	cobalamin metabolic process
DKB62_RS00155	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DKB62_RS00160	COG1114	Component of the transport system for branched-chain amino acids
DKB62_RS00165	COG0531	amino acid
DKB62_RS00175	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DKB62_RS00180	COG0534	Mate efflux family protein
DKB62_RS00195	COG1410	methionine synthase
DKB62_RS00195	COG0646	methionine synthase
DKB62_RS00225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DKB62_RS00240	COG0613	PHP domain protein
DKB62_RS00250	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DKB62_RS00255	COG2244	polysaccharide biosynthetic process
DKB62_RS00260	COG3956	TIGRFAM MazG family protein
DKB62_RS00265	COG0776	regulation of translation
DKB62_RS00275	COG2861	carbohydrate metabolic process
DKB62_RS00280	COG0730	response to heat
DKB62_RS00295	COG3339	Conserved Protein
DKB62_RS00305	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DKB62_RS00320	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DKB62_RS00330	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DKB62_RS00345	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DKB62_RS00350	COG1561	YicC-like family, N-terminal region
DKB62_RS00355	COG2052	Domain of unknown function (DUF370)
DKB62_RS00360	COG0194	GDP metabolic process
DKB62_RS00370	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DKB62_RS00375	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DKB62_RS00380	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DKB62_RS00385	COG0242	peptide deformylase activity
DKB62_RS00400	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DKB62_RS00400	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DKB62_RS00405	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DKB62_RS00410	COG0631	protein serine/threonine phosphatase activity
DKB62_RS00415	COG2815	serine threonine protein kinase
DKB62_RS00415	COG0515	serine threonine protein kinase
DKB62_RS00425	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DKB62_RS00430	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DKB62_RS00430	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DKB62_RS00440	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DKB62_RS00450	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DKB62_RS00455	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DKB62_RS00460	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DKB62_RS00465	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DKB62_RS00470	COG0402	S-adenosylhomocysteine deaminase activity
DKB62_RS00495	COG3206	protein involved in exopolysaccharide biosynthesis
DKB62_RS00515	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DKB62_RS00520	COG2814	Major facilitator Superfamily
DKB62_RS00530	COG0442	prolyl-tRNA aminoacylation
DKB62_RS00535	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DKB62_RS00540	COG0750	zinc metalloprotease
DKB62_RS00545	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DKB62_RS00550	COG4589	Belongs to the CDS family
DKB62_RS00555	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DKB62_RS00565	COG0233	cytoplasmic translational termination
DKB62_RS00570	COG0528	UMP kinase activity
DKB62_RS00575	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DKB62_RS00580	COG0052	Belongs to the universal ribosomal protein uS2 family
DKB62_RS00585	COG3584	3D domain protein
DKB62_RS00585	COG1388	LysM domain
DKB62_RS00590	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DKB62_RS00600	COG0248	Ppx GppA phosphatase
DKB62_RS00600	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DKB62_RS00605	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DKB62_RS00610	COG1028	Short-chain dehydrogenase reductase Sdr
DKB62_RS00615	COG0583	DNA-binding transcription factor activity
DKB62_RS00625	COG0667	Aldo Keto reductase
DKB62_RS00630	COG4221	oxidoreductase activity
DKB62_RS00640	COG2003	Belongs to the UPF0758 family
DKB62_RS00645	COG0424	maF-like protein
DKB62_RS00655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DKB62_RS00665	COG3464	Transposase
DKB62_RS00670	COG0179	Fumarylacetoacetate (FAA) hydrolase
DKB62_RS00685	COG1994	Peptidase M50
DKB62_RS00695	COG2814	Major facilitator Superfamily
DKB62_RS00710	COG0765	amino acid transport
DKB62_RS00720	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DKB62_RS00745	COG1797	cobyrinic acid a,c-diamide synthase activity
DKB62_RS00780	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DKB62_RS00785	COG1120	ATPase activity
DKB62_RS00790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DKB62_RS00795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DKB62_RS00800	COG4771	TonB-dependent receptor
DKB62_RS00810	COG0848	biopolymer transport protein
DKB62_RS00815	COG0811	peptide transport
DKB62_RS00850	COG3464	Transposase
DKB62_RS00870	COG2078	PFAM AMMECR1 domain protein
DKB62_RS00870	COG3885	ferrous iron binding
DKB62_RS00890	COG0242	peptide deformylase activity
DKB62_RS00900	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DKB62_RS00905	COG3610	response to peptide
DKB62_RS00910	COG0210	DNA helicase
DKB62_RS00915	COG1227	inorganic diphosphatase activity
DKB62_RS00920	COG0335	large ribosomal subunit rRNA binding
DKB62_RS00925	COG0697	spore germination
DKB62_RS00940	COG0752	glycyl-tRNA synthetase alpha subunit
DKB62_RS00950	COG1959	2 iron, 2 sulfur cluster binding
DKB62_RS00955	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DKB62_RS00960	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DKB62_RS00975	COG0569	domain protein
DKB62_RS00980	COG2244	polysaccharide biosynthetic process
DKB62_RS01000	COG3041	Addiction module toxin RelE StbE family
DKB62_RS01055	COG1733	regulation of RNA biosynthetic process
DKB62_RS01140	COG1484	DNA-dependent DNA replication
DKB62_RS01190	COG1395	domain, Protein
DKB62_RS01230	COG4962	Type ii secretion system protein e
DKB62_RS01245	COG3451	type IV secretory pathway VirB4
DKB62_RS01300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DKB62_RS01340	COG2003	Belongs to the UPF0758 family
DKB62_RS01380	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DKB62_RS01400	COG1396	sequence-specific DNA binding
DKB62_RS01525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DKB62_RS01530	COG0358	DNA primase activity
DKB62_RS01535	COG0564	pseudouridine synthase activity
DKB62_RS01540	COG0191	fructose-bisphosphate aldolase activity
DKB62_RS01545	COG0268	Binds directly to 16S ribosomal RNA
DKB62_RS01550	COG0534	Mate efflux family protein
DKB62_RS01555	COG2309	aminopeptidase activity
DKB62_RS01575	COG1250	3-hydroxyacyl-CoA dehydrogenase
DKB62_RS01580	COG2031	fatty acid transporter
DKB62_RS01600	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DKB62_RS01605	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DKB62_RS01620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DKB62_RS01630	COG0114	fumarate hydratase activity
DKB62_RS01640	COG0138	bifunctional purine biosynthesis protein purh
DKB62_RS01650	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DKB62_RS01655	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DKB62_RS01660	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DKB62_RS01665	COG0167	dihydroorotate dehydrogenase activity
DKB62_RS01670	COG0543	2 iron, 2 sulfur cluster binding
DKB62_RS01680	COG0745	RESPONSE REGULATOR receiver
DKB62_RS01685	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DKB62_RS01690	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DKB62_RS01695	COG0302	gtp cyclohydrolase
DKB62_RS01720	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DKB62_RS01730	COG0681	Belongs to the peptidase S26 family
DKB62_RS01760	COG0456	acetyltransferase
DKB62_RS01770	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DKB62_RS01780	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DKB62_RS01785	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DKB62_RS01790	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DKB62_RS01795	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DKB62_RS01800	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DKB62_RS01805	COG0356	it plays a direct role in the translocation of protons across the membrane
DKB62_RS01820	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DKB62_RS01825	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DKB62_RS01830	COG2848	UPF0210 protein
DKB62_RS01840	COG0033	Phosphoglucomutase
DKB62_RS01845	COG0708	Exodeoxyribonuclease III
DKB62_RS01850	COG0174	glutamine synthetase
DKB62_RS01865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DKB62_RS01870	COG0481	GTPase activity
DKB62_RS01875	COG0482	sulfurtransferase activity
DKB62_RS01895	COG0583	DNA-binding transcription factor activity
DKB62_RS01920	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DKB62_RS01935	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DKB62_RS01935	COG1918	ferrous iron import across plasma membrane
DKB62_RS01950	COG1132	(ABC) transporter
DKB62_RS01960	COG4771	TonB-dependent receptor
DKB62_RS01965	COG1120	ATPase activity
DKB62_RS01975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DKB62_RS02010	COG0848	biopolymer transport protein
DKB62_RS02015	COG0811	peptide transport
DKB62_RS02095	COG0583	DNA-binding transcription factor activity
DKB62_RS02100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DKB62_RS02105	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DKB62_RS02120	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DKB62_RS02125	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DKB62_RS02135	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DKB62_RS02145	COG0667	Aldo Keto reductase
DKB62_RS02180	COG1073	alpha beta
DKB62_RS02200	COG0583	DNA-binding transcription factor activity
DKB62_RS02205	COG0129	dihydroxy-acid dehydratase activity
DKB62_RS02210	COG3246	L-lysine catabolic process to acetate
DKB62_RS02220	COG2814	Major facilitator Superfamily
DKB62_RS02230	COG1683	Conserved Protein
DKB62_RS02240	COG0471	metal ion transport
DKB62_RS02260	COG4770	biotin carboxylase activity
DKB62_RS02270	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DKB62_RS02300	COG0582	viral genome integration into host DNA
DKB62_RS02310	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DKB62_RS02315	COG1012	belongs to the aldehyde dehydrogenase family
DKB62_RS02320	COG2033	superoxide reductase activity
DKB62_RS02330	COG0583	DNA-binding transcription factor activity
DKB62_RS02335	COG3906	Belongs to the UPF0473 family
DKB62_RS02345	COG4472	Bacterial protein of unknown function (DUF965)
DKB62_RS02350	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DKB62_RS02355	COG0791	NLP P60 protein
DKB62_RS02355	COG1388	LysM domain
DKB62_RS02360	COG0463	Glycosyl transferase, family 2
DKB62_RS02365	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DKB62_RS02370	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DKB62_RS02385	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DKB62_RS02390	COG0740	serine-type endopeptidase activity
DKB62_RS02395	COG0544	peptidyl-prolyl cis-trans isomerase activity
DKB62_RS02400	COG0072	phenylalanine-tRNA ligase activity
DKB62_RS02400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DKB62_RS02405	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DKB62_RS02410	COG1960	acyl-CoA dehydrogenase activity
DKB62_RS02445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DKB62_RS02450	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DKB62_RS02450	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DKB62_RS02455	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DKB62_RS02460	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DKB62_RS02470	COG1181	Belongs to the D-alanine--D-alanine ligase family
DKB62_RS02475	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DKB62_RS02480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DKB62_RS02490	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DKB62_RS02495	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DKB62_RS02500	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DKB62_RS02505	COG4839	cell division protein FtsL
DKB62_RS02510	COG0275	rRNA processing
DKB62_RS02520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DKB62_RS02535	COG0110	maltose O-acetyltransferase activity
DKB62_RS02540	COG0622	Phosphoesterase
DKB62_RS02555	COG1217	gtp-binding protein TYPA
DKB62_RS02560	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DKB62_RS02570	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DKB62_RS02580	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DKB62_RS02585	COG3404	Formiminotransferase-cyclodeaminase
DKB62_RS02600	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DKB62_RS02605	COG0124	histidyl-tRNA synthetase
DKB62_RS02610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DKB62_RS02615	COG0735	belongs to the Fur family
DKB62_RS02620	COG0628	permease
DKB62_RS02625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKB62_RS02630	COG1490	D-aminoacyl-tRNA deacylase activity
DKB62_RS02635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DKB62_RS02640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DKB62_RS02640	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DKB62_RS02650	COG0583	DNA-binding transcription factor activity
DKB62_RS02660	COG0542	response to heat
DKB62_RS02665	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DKB62_RS02670	COG3880	PFAM UvrB UvrC protein
DKB62_RS02675	COG4463	regulation of RNA biosynthetic process
DKB62_RS02705	COG0322	excinuclease ABC activity
DKB62_RS02710	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DKB62_RS02715	COG0556	nucleotide-excision repair
DKB62_RS02735	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DKB62_RS02745	COG0697	spore germination
DKB62_RS02750	COG0561	phosphatase activity
DKB62_RS02755	COG0129	dihydroxy-acid dehydratase activity
DKB62_RS02765	COG3328	transposase activity
DKB62_RS02780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DKB62_RS02785	COG2721	sulfolactate sulfo-lyase activity
DKB62_RS02790	COG2826	transposase and inactivated derivatives, IS30 family
DKB62_RS02795	COG2721	sulfolactate sulfo-lyase activity
DKB62_RS02805	COG0129	dihydroxy-acid dehydratase activity
DKB62_RS02810	COG2030	dehydratase
DKB62_RS02820	COG1013	pyruvate-flavodoxin oxidoreductase activity
DKB62_RS02820	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DKB62_RS02820	COG0674	pyruvate-flavodoxin oxidoreductase activity
DKB62_RS02820	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DKB62_RS02830	COG1414	Transcriptional regulator
DKB62_RS02835	COG1979	alcohol dehydrogenase
DKB62_RS02840	COG1028	Short-chain dehydrogenase reductase Sdr
DKB62_RS02850	COG0277	FAD linked oxidase domain protein
DKB62_RS02855	COG2271	Major facilitator Superfamily
DKB62_RS02865	COG2271	Major facilitator Superfamily
DKB62_RS02870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DKB62_RS02875	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DKB62_RS02880	COG1862	Preprotein translocase
DKB62_RS02885	COG0343	queuine tRNA-ribosyltransferase activity
DKB62_RS02895	COG2385	sporulation resulting in formation of a cellular spore
DKB62_RS02905	COG2255	four-way junction helicase activity
DKB62_RS02910	COG0632	four-way junction helicase activity
DKB62_RS02915	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DKB62_RS02920	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DKB62_RS02930	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DKB62_RS02960	COG3842	ATPase activity
DKB62_RS02985	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DKB62_RS02995	COG0546	phosphoglycolate phosphatase activity
DKB62_RS03000	COG1361	Conserved repeat domain
DKB62_RS03005	COG1361	Conserved repeat domain
DKB62_RS03025	COG4864	UPF0365 protein
DKB62_RS03030	COG1030	water channel activity
DKB62_RS03040	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
DKB62_RS03045	COG0180	Tryptophanyl-tRNA synthetase
DKB62_RS03055	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DKB62_RS03080	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DKB62_RS03085	COG2873	o-acetylhomoserine
DKB62_RS03100	COG0698	ribose 5-phosphate isomerase
DKB62_RS03105	COG0009	L-threonylcarbamoyladenylate synthase
DKB62_RS03110	COG2890	protein-(glutamine-N5) methyltransferase activity
DKB62_RS03115	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DKB62_RS03120	COG3872	metal-dependent enzyme
DKB62_RS03125	COG0254	rRNA binding
DKB62_RS03130	COG0602	queuosine metabolic process
DKB62_RS03140	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DKB62_RS03145	COG0346	lactoylglutathione lyase activity
DKB62_RS03150	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DKB62_RS03155	COG0419	ATPase involved in DNA repair
DKB62_RS03160	COG0420	3'-5' exonuclease activity
DKB62_RS03165	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DKB62_RS03175	COG2183	response to ionizing radiation
DKB62_RS03195	COG2814	Major facilitator Superfamily
DKB62_RS03200	COG0459	protein refolding
DKB62_RS03205	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DKB62_RS03220	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DKB62_RS03225	COG0456	acetyltransferase
DKB62_RS03230	COG1214	PFAM Peptidase M22, glycoprotease
DKB62_RS03235	COG0802	atpase or kinase
DKB62_RS03240	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DKB62_RS03270	COG1827	regulation of RNA biosynthetic process
DKB62_RS03305	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DKB62_RS03310	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DKB62_RS03315	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DKB62_RS03330	COG0861	Integral membrane protein TerC family
DKB62_RS03340	COG0277	FAD linked oxidase domain protein
DKB62_RS03345	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DKB62_RS03350	COG1115	amino acid carrier protein
DKB62_RS03375	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DKB62_RS03390	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DKB62_RS03400	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DKB62_RS03405	COG1959	2 iron, 2 sulfur cluster binding
DKB62_RS03410	COG0306	phosphate transporter
DKB62_RS03415	COG1392	Phosphate transport regulator
DKB62_RS03420	COG2213	PTS system mannitol-specific
DKB62_RS03420	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKB62_RS03425	COG3711	transcriptional antiterminator
DKB62_RS03435	COG1063	alcohol dehydrogenase
DKB62_RS03445	COG0149	triose-phosphate isomerase activity
DKB62_RS03450	COG0126	phosphoglycerate kinase activity
DKB62_RS03455	COG2390	Transcriptional regulator
DKB62_RS03470	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DKB62_RS03480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DKB62_RS03490	COG1620	l-lactate permease
DKB62_RS03500	COG2062	phosphohistidine phosphatase, SixA
DKB62_RS03505	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DKB62_RS03505	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DKB62_RS03505	COG1013	pyruvate-flavodoxin oxidoreductase activity
DKB62_RS03505	COG0674	pyruvate-flavodoxin oxidoreductase activity
DKB62_RS03510	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DKB62_RS03515	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DKB62_RS03520	COG0768	penicillin binding
DKB62_RS03525	COG0617	tRNA 3'-terminal CCA addition
DKB62_RS03535	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
DKB62_RS03540	COG1473	amidohydrolase
DKB62_RS03545	COG2814	Major facilitator Superfamily
DKB62_RS03550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DKB62_RS03555	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DKB62_RS03560	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DKB62_RS03580	COG1349	DNA-binding transcription factor activity
DKB62_RS03595	COG2195	Cleaves the N-terminal amino acid of tripeptides
DKB62_RS03635	COG0443	Heat shock 70 kDa protein
DKB62_RS03650	COG0443	Heat shock 70 kDa protein
DKB62_RS03670	COG0443	Heat shock 70 kDa protein
DKB62_RS03720	COG2826	transposase and inactivated derivatives, IS30 family
DKB62_RS03765	COG1051	belongs to the nudix hydrolase family
DKB62_RS03775	COG0203	ribosomal protein L17
DKB62_RS03780	COG0202	RNA polymerase activity
DKB62_RS03790	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DKB62_RS03795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DKB62_RS03815	COG0563	adenylate kinase activity
DKB62_RS03820	COG0201	protein transport
DKB62_RS03825	COG0200	Binds to the 23S rRNA
DKB62_RS03830	COG1841	ribosomal large subunit assembly
DKB62_RS03835	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DKB62_RS03840	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DKB62_RS03845	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DKB62_RS03850	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DKB62_RS03855	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DKB62_RS03865	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DKB62_RS03870	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DKB62_RS03875	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DKB62_RS03880	COG0255	Belongs to the universal ribosomal protein uL29 family
DKB62_RS03885	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DKB62_RS03890	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DKB62_RS03895	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DKB62_RS03900	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DKB62_RS03910	COG0089	rRNA binding
DKB62_RS03915	COG0088	Forms part of the polypeptide exit tunnel
DKB62_RS03920	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DKB62_RS03930	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DKB62_RS03940	COG0049	tRNA binding
DKB62_RS03945	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DKB62_RS03955	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DKB62_RS03960	COG0085	RNA polymerase activity
DKB62_RS03970	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DKB62_RS03975	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
DKB62_RS03980	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DKB62_RS03995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DKB62_RS04000	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DKB62_RS04005	COG1573	uracil-dna glycosylase
DKB62_RS04045	COG2030	dehydratase
DKB62_RS04055	COG2610	gluconate transmembrane transporter activity
DKB62_RS04060	COG2030	dehydratase
DKB62_RS04070	COG2610	gluconate transmembrane transporter activity
DKB62_RS04075	COG0583	DNA-binding transcription factor activity
DKB62_RS04080	COG4670	ketone body catabolic process
DKB62_RS04110	COG0710	3-dehydroquinate dehydratase activity
DKB62_RS04115	COG2271	Major facilitator Superfamily
DKB62_RS04120	COG0738	Major facilitator superfamily
DKB62_RS04130	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DKB62_RS04140	COG0583	DNA-binding transcription factor activity
DKB62_RS04145	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DKB62_RS04150	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DKB62_RS04160	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DKB62_RS04165	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DKB62_RS04170	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DKB62_RS04180	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DKB62_RS04185	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DKB62_RS04220	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DKB62_RS04235	COG1760	l-serine dehydratase
DKB62_RS04240	COG1760	l-serine dehydratase
DKB62_RS04245	COG1074	ATP-dependent DNA helicase activity
DKB62_RS04250	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DKB62_RS04260	COG1414	Transcriptional regulator
DKB62_RS04270	COG0668	transmembrane transport
DKB62_RS04275	COG0165	Argininosuccinate lyase
DKB62_RS04285	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DKB62_RS04325	COG0616	signal peptide processing
DKB62_RS04330	COG0305	Participates in initiation and elongation during chromosome replication
DKB62_RS04335	COG1067	ATP-dependent peptidase activity
DKB62_RS04335	COG0470	DNA polymerase III
DKB62_RS04345	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DKB62_RS04355	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DKB62_RS04365	COG0351	phosphomethylpyrimidine kinase
DKB62_RS04365	COG0352	thiamine-phosphate diphosphorylase activity
DKB62_RS04380	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DKB62_RS04405	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DKB62_RS04415	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DKB62_RS04435	COG1127	ABC transporter
DKB62_RS04440	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DKB62_RS04460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DKB62_RS04465	COG1121	(ABC) transporter
DKB62_RS04470	COG0803	Belongs to the bacterial solute-binding protein 9 family
DKB62_RS04480	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DKB62_RS04505	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DKB62_RS04510	COG0166	Belongs to the GPI family
DKB62_RS04515	COG1115	amino acid carrier protein
DKB62_RS04520	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DKB62_RS04535	COG0688	phosphatidylethanolamine metabolic process
DKB62_RS04545	COG0516	GMP reductase activity
DKB62_RS04545	COG0517	IMP dehydrogenase activity
DKB62_RS04550	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DKB62_RS04555	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DKB62_RS04575	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DKB62_RS04580	COG0517	IMP dehydrogenase activity
DKB62_RS04590	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DKB62_RS04590	COG0574	Belongs to the PEP-utilizing enzyme family
DKB62_RS04595	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DKB62_RS04605	COG1803	Methylglyoxal synthase
DKB62_RS04610	COG3590	peptidase
DKB62_RS04615	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DKB62_RS04620	COG0697	spore germination
DKB62_RS04625	COG0531	amino acid
DKB62_RS04640	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DKB62_RS04645	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DKB62_RS04650	COG4149	molybdate abc transporter
DKB62_RS04655	COG0725	ABC transporter, periplasmic molybdate-binding protein
DKB62_RS04660	COG0521	Mo-molybdopterin cofactor biosynthetic process
DKB62_RS04670	COG0315	cyclic pyranopterin monophosphate synthase activity
DKB62_RS04690	COG3468	outer membrane autotransporter barrel domain protein
DKB62_RS04695	COG0746	molybdenum cofactor guanylyltransferase activity
DKB62_RS04710	COG0303	'Molybdopterin
DKB62_RS04720	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DKB62_RS04720	COG3608	succinylglutamate desuccinylase aspartoacylase
DKB62_RS04750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKB62_RS04760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKB62_RS04770	COG1481	regulation of sporulation
DKB62_RS04775	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DKB62_RS04780	COG1660	Displays ATPase and GTPase activities
DKB62_RS04785	COG0561	phosphatase activity
DKB62_RS04800	COG2302	S4 RNA-binding domain
DKB62_RS04805	COG1799	cell septum assembly
DKB62_RS04835	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DKB62_RS04860	COG3328	transposase activity
DKB62_RS04870	COG3842	ATPase activity
DKB62_RS04875	COG0805	protein transport
DKB62_RS04880	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DKB62_RS04920	COG2194	sulfuric ester hydrolase activity
DKB62_RS04930	COG1686	Belongs to the peptidase S11 family
DKB62_RS04940	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DKB62_RS04945	COG1937	Protein conserved in bacteria
DKB62_RS04950	COG2814	Major facilitator Superfamily
DKB62_RS04960	COG0277	FAD linked oxidase domain protein
DKB62_RS04965	COG0039	L-malate dehydrogenase activity
DKB62_RS04980	COG0159	tryptophan synthase activity
DKB62_RS04985	COG0133	tryptophan synthase activity
DKB62_RS04995	COG0134	indole-3-glycerol-phosphate synthase activity
DKB62_RS05005	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DKB62_RS05005	COG0512	Glutamine amidotransferase of anthranilate synthase
DKB62_RS05015	COG0814	amino acid
DKB62_RS05030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DKB62_RS05055	COG2721	sulfolactate sulfo-lyase activity
DKB62_RS05085	COG2357	RelA SpoT domain protein
DKB62_RS05090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DKB62_RS05110	COG1122	ATPase activity
DKB62_RS05125	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DKB62_RS05130	COG1687	branched-chain amino acid
DKB62_RS05150	COG0427	acetyl-CoA hydrolase
DKB62_RS05155	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DKB62_RS05160	COG1473	amidohydrolase
DKB62_RS05165	COG1362	aminopeptidase activity
DKB62_RS05170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DKB62_RS05175	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DKB62_RS05180	COG2826	transposase and inactivated derivatives, IS30 family
DKB62_RS05185	COG2271	Major facilitator Superfamily
DKB62_RS05190	COG2814	Major facilitator Superfamily
DKB62_RS05200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DKB62_RS05205	COG0583	DNA-binding transcription factor activity
DKB62_RS05215	COG1971	Probably functions as a manganese efflux pump
DKB62_RS05220	COG0193	aminoacyl-tRNA hydrolase activity
DKB62_RS05230	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DKB62_RS05235	COG3584	3D domain protein
DKB62_RS05235	COG1388	LysM domain
DKB62_RS05255	COG1473	amidohydrolase
DKB62_RS05265	COG0004	ammonium transporteR
DKB62_RS05270	COG0347	Belongs to the P(II) protein family
DKB62_RS05285	COG0861	Integral membrane protein TerC family
DKB62_RS05300	COG1285	pathogenesis
DKB62_RS05310	COG0586	Pfam SNARE associated Golgi protein
DKB62_RS05315	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DKB62_RS05320	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DKB62_RS05330	COG0069	glutamate synthase activity
DKB62_RS05330	COG0070	glutamate synthase
DKB62_RS05330	COG0067	glutamate synthase
DKB62_RS05335	COG0656	L-ascorbic acid biosynthetic process
DKB62_RS05345	COG0667	Aldo Keto reductase
DKB62_RS05350	COG1028	Short-chain dehydrogenase reductase Sdr
DKB62_RS05355	COG0656	L-ascorbic acid biosynthetic process
DKB62_RS05370	COG0583	DNA-binding transcription factor activity
DKB62_RS05375	COG0697	spore germination
DKB62_RS05385	COG0385	Bile acid
DKB62_RS05390	COG1253	flavin adenine dinucleotide binding
DKB62_RS05430	COG0583	DNA-binding transcription factor activity
DKB62_RS05435	COG0129	dihydroxy-acid dehydratase activity
DKB62_RS05440	COG0440	acetolactate synthase activity
DKB62_RS05445	COG0028	Belongs to the TPP enzyme family
DKB62_RS05450	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DKB62_RS05460	COG1196	nuclear chromosome segregation
DKB62_RS05495	COG0436	Aminotransferase
DKB62_RS05500	COG0012	GTP binding
DKB62_RS05505	COG1396	sequence-specific DNA binding
DKB62_RS05510	COG0277	FAD linked oxidase domain protein
DKB62_RS05515	COG0488	(ABC) transporter
DKB62_RS05535	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DKB62_RS05540	COG1982	Orn Lys Arg decarboxylase major
DKB62_RS05545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DKB62_RS05550	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DKB62_RS05560	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DKB62_RS05565	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DKB62_RS05575	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DKB62_RS05580	COG0540	Belongs to the ATCase OTCase family
DKB62_RS05590	COG0697	spore germination
DKB62_RS05600	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DKB62_RS05605	COG0284	orotidine-5'-phosphate decarboxylase activity
DKB62_RS05630	COG1979	alcohol dehydrogenase
DKB62_RS05635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DKB62_RS05640	COG1396	sequence-specific DNA binding
DKB62_RS05650	COG1882	Formate acetyltransferase
DKB62_RS05655	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DKB62_RS05655	COG0517	IMP dehydrogenase activity
DKB62_RS05655	COG0617	tRNA 3'-terminal CCA addition
DKB62_RS05695	COG0288	reversible hydration of carbon dioxide
DKB62_RS05705	COG1027	Aspartate ammonia-lyase
DKB62_RS05710	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DKB62_RS05725	COG1473	amidohydrolase
DKB62_RS05730	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DKB62_RS05735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKB62_RS05735	COG1263	PTS System
DKB62_RS05770	COG4336	lyase activity
DKB62_RS05775	COG0439	Biotin carboxylase
DKB62_RS05780	COG0511	ligase activity, forming carbon-carbon bonds
DKB62_RS05785	COG1984	allophanate hydrolase subunit 2
DKB62_RS05790	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DKB62_RS05795	COG1914	H( )-stimulated, divalent metal cation uptake system
DKB62_RS05800	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DKB62_RS05820	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DKB62_RS05820	COG0456	acetyltransferase
DKB62_RS05825	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DKB62_RS05840	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DKB62_RS05845	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DKB62_RS05855	COG1921	L-seryl-tRNASec selenium transferase activity
DKB62_RS05880	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DKB62_RS05890	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DKB62_RS05900	COG0280	phosphate acetyltransferase
DKB62_RS05940	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DKB62_RS05945	COG0371	Dehydrogenase
DKB62_RS05950	COG1966	Carbon starvation protein
DKB62_RS05970	COG2733	membrane
DKB62_RS05975	COG2733	membrane
DKB62_RS05985	COG0745	RESPONSE REGULATOR receiver
DKB62_RS05990	COG5002	protein histidine kinase activity
DKB62_RS06020	COG1619	proteins homologs of microcin C7 resistance protein MccF
DKB62_RS06025	COG4166	transmembrane transport
DKB62_RS06030	COG4608	Belongs to the ABC transporter superfamily
DKB62_RS06035	COG0444	Belongs to the ABC transporter superfamily
DKB62_RS06040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DKB62_RS06045	COG0601	transmembrane transport
DKB62_RS06065	COG2610	gluconate transmembrane transporter activity
DKB62_RS06140	COG2826	transposase and inactivated derivatives, IS30 family
DKB62_RS06150	COG2610	gluconate transmembrane transporter activity
DKB62_RS06155	COG1024	Enoyl-CoA hydratase
DKB62_RS06165	COG1960	acyl-CoA dehydrogenase activity
DKB62_RS06170	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DKB62_RS06175	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DKB62_RS06185	COG2814	Major facilitator Superfamily
DKB62_RS06195	COG2195	Cleaves the N-terminal amino acid of tripeptides
DKB62_RS06200	COG1297	OPT oligopeptide transporter protein
DKB62_RS06210	COG1757	Na H antiporter
DKB62_RS06220	COG4221	oxidoreductase activity
DKB62_RS06225	COG0561	phosphatase activity
DKB62_RS06235	COG1115	amino acid carrier protein
DKB62_RS06245	COG1349	DNA-binding transcription factor activity
DKB62_RS06250	COG2271	Major facilitator Superfamily
DKB62_RS06255	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DKB62_RS06260	COG0737	Belongs to the 5'-nucleotidase family
DKB62_RS06265	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DKB62_RS06280	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
DKB62_RS06300	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DKB62_RS06315	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
DKB62_RS06335	COG1024	Enoyl-CoA hydratase
DKB62_RS06350	COG2326	polyphosphate kinase activity
DKB62_RS06360	COG0385	Bile acid
DKB62_RS06390	COG1373	ATPase (AAA superfamily
DKB62_RS06400	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DKB62_RS06405	COG1518	maintenance of DNA repeat elements
DKB62_RS06445	COG2094	Belongs to the DNA glycosylase MPG family
DKB62_RS06450	COG1414	Transcriptional regulator
DKB62_RS06455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DKB62_RS06465	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DKB62_RS06470	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DKB62_RS06475	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DKB62_RS06485	COG4187	Peptidase family M20/M25/M40
DKB62_RS06500	COG1960	acyl-CoA dehydrogenase activity
DKB62_RS06545	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DKB62_RS06565	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DKB62_RS06585	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DKB62_RS06595	COG0473	3-isopropylmalate dehydrogenase activity
DKB62_RS06630	COG0347	Belongs to the P(II) protein family
DKB62_RS06635	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DKB62_RS06640	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DKB62_RS06650	COG2508	Transcriptional regulator
DKB62_RS06655	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DKB62_RS06675	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
DKB62_RS06680	COG1253	flavin adenine dinucleotide binding
DKB62_RS06695	COG0436	Aminotransferase
DKB62_RS06700	COG0187	DNA topoisomerase II activity
DKB62_RS06715	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DKB62_RS06720	COG2501	S4 domain
DKB62_RS06725	COG0592	DNA-directed DNA polymerase activity
DKB62_RS06730	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DKB62_RS06735	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DKB62_RS06745	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DKB62_RS06755	COG1847	R3H domain protein
DKB62_RS06760	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DKB62_RS06765	COG0445	tRNA wobble uridine modification
DKB62_RS06770	COG0357	Ribosomal RNA small subunit methyltransferase G
DKB62_RS06775	COG1686	Belongs to the peptidase S11 family
DKB62_RS06785	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DKB62_RS06795	COG1349	DNA-binding transcription factor activity
DKB62_RS06800	COG1105	Belongs to the carbohydrate kinase PfkB family
DKB62_RS06805	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DKB62_RS06805	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKB62_RS06805	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DKB62_RS06820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKB62_RS06825	COG0534	Mate efflux family protein
DKB62_RS06840	COG0385	Bile acid
DKB62_RS06845	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DKB62_RS06850	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DKB62_RS06860	COG3464	Transposase
DKB62_RS06875	COG2878	Part of a membrane complex involved in electron transport
DKB62_RS06880	COG1733	regulation of RNA biosynthetic process
DKB62_RS06900	COG0789	Transcriptional regulator
DKB62_RS06905	COG0745	RESPONSE REGULATOR receiver
DKB62_RS06910	COG5002	protein histidine kinase activity
DKB62_RS06920	COG2217	Heavy metal translocating P-type atpase
DKB62_RS06925	COG1937	Protein conserved in bacteria
DKB62_RS06930	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DKB62_RS06935	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DKB62_RS06940	COG1024	Enoyl-CoA hydratase
DKB62_RS06945	COG0427	acetyl-CoA hydrolase
DKB62_RS06950	COG0640	Transcriptional regulator
DKB62_RS06955	COG0701	Predicted permease
DKB62_RS06995	COG2003	Belongs to the UPF0758 family
DKB62_RS07010	COG0210	DNA helicase
DKB62_RS07035	COG4372	Transposase
DKB62_RS07035	COG1418	mRNA catabolic process
DKB62_RS07040	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DKB62_RS07045	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DKB62_RS07050	COG0110	maltose O-acetyltransferase activity
DKB62_RS07065	COG1192	Involved in chromosome partitioning
DKB62_RS07070	COG1475	DNA binding
DKB62_RS07080	COG0739	heme binding
DKB62_RS07100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DKB62_RS07105	COG1312	Catalyzes the dehydration of D-mannonate
DKB62_RS07110	COG0246	Mannitol dehydrogenase
DKB62_RS07115	COG1063	alcohol dehydrogenase
DKB62_RS07120	COG0477	Major facilitator Superfamily
DKB62_RS07125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DKB62_RS07135	COG3949	Membrane
DKB62_RS07140	COG1802	Transcriptional regulator
DKB62_RS07160	COG0860	N-Acetylmuramoyl-L-alanine amidase
DKB62_RS07180	COG5295	Hep Hag repeat protein
DKB62_RS07220	COG1597	lipid kinase activity
DKB62_RS07235	COG0814	amino acid
DKB62_RS07240	COG3681	Belongs to the UPF0597 family
DKB62_RS07255	COG1982	Orn Lys Arg decarboxylase major
DKB62_RS07260	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DKB62_RS07270	COG1774	PSP1 C-terminal conserved region
DKB62_RS07275	COG2890	protein-(glutamine-N5) methyltransferase activity
DKB62_RS07280	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DKB62_RS07290	COG0084	hydrolase, TatD family'
DKB62_RS07300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKB62_RS07305	COG0626	cystathionine gamma-synthase activity
DKB62_RS07310	COG0583	DNA-binding transcription factor activity
DKB62_RS07320	COG1349	DNA-binding transcription factor activity
DKB62_RS07340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DKB62_RS07350	COG1454	alcohol dehydrogenase
DKB62_RS07360	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DKB62_RS07375	COG0583	DNA-binding transcription factor activity
DKB62_RS07390	COG1388	LysM domain
DKB62_RS07390	COG0791	NLP P60 protein
DKB62_RS07395	COG2197	response regulator
DKB62_RS07420	COG2826	transposase and inactivated derivatives, IS30 family
DKB62_RS07425	COG0583	DNA-binding transcription factor activity
DKB62_RS07430	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DKB62_RS07465	COG2217	Heavy metal translocating P-type atpase
DKB62_RS07470	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DKB62_RS07490	COG0360	Binds together with S18 to 16S ribosomal RNA
DKB62_RS07495	COG0629	single-stranded DNA binding
DKB62_RS07500	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DKB62_RS07530	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DKB62_RS07540	COG0602	queuosine metabolic process
DKB62_RS07545	COG0302	gtp cyclohydrolase
DKB62_RS07555	COG0306	phosphate transporter
DKB62_RS07565	COG0039	L-malate dehydrogenase activity
DKB62_RS07570	COG2233	PERMEase
DKB62_RS07575	COG1376	ErfK ybiS ycfS ynhG family protein
DKB62_RS07600	COG1342	Belongs to the UPF0251 family
DKB62_RS07605	COG3290	protein histidine kinase activity
DKB62_RS07605	COG3829	transcription factor binding
DKB62_RS07610	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DKB62_RS07615	COG0318	PFAM AMP-dependent synthetase and ligase
DKB62_RS07630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKB62_RS07645	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DKB62_RS07645	COG0316	Belongs to the HesB IscA family
DKB62_RS07655	COG0371	Dehydrogenase
DKB62_RS07665	COG0352	thiamine-phosphate diphosphorylase activity
DKB62_RS07675	COG2022	thiamine diphosphate biosynthetic process
DKB62_RS07760	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DKB62_RS07770	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DKB62_RS07775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DKB62_RS07780	COG0420	3'-5' exonuclease activity
DKB62_RS07810	COG2851	Citrate transporter
DKB62_RS07815	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DKB62_RS07820	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DKB62_RS07825	COG0250	Participates in transcription elongation, termination and antitermination
DKB62_RS07830	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DKB62_RS07835	COG0081	regulation of translation
DKB62_RS07840	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DKB62_RS07845	COG0222	ribosome binding
DKB62_RS07850	COG5505	Protein of unknown function (DUF819)
DKB62_RS07855	COG0656	L-ascorbic acid biosynthetic process
DKB62_RS07860	COG0583	DNA-binding transcription factor activity
DKB62_RS07870	COG2814	Major facilitator Superfamily
DKB62_RS07875	COG2814	Major facilitator Superfamily
DKB62_RS07965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKB62_RS07965	COG2190	(PTS) system
DKB62_RS07965	COG1263	PTS System
DKB62_RS07985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DKB62_RS08015	COG3118	belongs to the thioredoxin family
DKB62_RS08035	COG1464	Belongs to the NlpA lipoprotein family
DKB62_RS08040	COG1592	Rubrerythrin
DKB62_RS08060	COG4481	Protein conserved in bacteria
DKB62_RS08065	COG0124	histidyl-tRNA synthetase
DKB62_RS08070	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DKB62_RS08075	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DKB62_RS08080	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DKB62_RS08085	COG0131	Imidazoleglycerol-phosphate dehydratase
DKB62_RS08090	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DKB62_RS08095	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DKB62_RS08100	COG0107	imidazoleglycerol-phosphate synthase activity
DKB62_RS08105	COG0140	phosphoribosyl-ATP diphosphatase activity
DKB62_RS08105	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DKB62_RS08125	COG2211	Major facilitator Superfamily
DKB62_RS08130	COG2721	sulfolactate sulfo-lyase activity
DKB62_RS08140	COG1904	glucuronate isomerase
DKB62_RS08145	COG1609	Transcriptional regulator
DKB62_RS08150	COG4948	Mandelate Racemase Muconate Lactonizing
DKB62_RS08155	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DKB62_RS08160	COG0772	Belongs to the SEDS family
DKB62_RS08170	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DKB62_RS08205	COG0726	polysaccharide deacetylase
DKB62_RS08210	COG5434	Belongs to the glycosyl hydrolase 28 family
DKB62_RS08210	COG4632	Exopolysaccharide biosynthesis protein
DKB62_RS08235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKB62_RS08240	COG0765	amino acid transport
DKB62_RS08245	COG1126	abc transporter atp-binding protein
DKB62_RS08250	COG3468	outer membrane autotransporter barrel domain protein
DKB62_RS08260	COG2271	Major facilitator Superfamily
DKB62_RS08265	COG1136	(ABC) transporter
DKB62_RS08265	COG0577	efflux transmembrane transporter activity
DKB62_RS08270	COG1136	(ABC) transporter
DKB62_RS08310	COG1733	regulation of RNA biosynthetic process
DKB62_RS08315	COG1733	regulation of RNA biosynthetic process
DKB62_RS08325	COG2084	Dehydrogenase
DKB62_RS08335	COG0730	response to heat
DKB62_RS08340	COG0436	Aminotransferase
DKB62_RS08345	COG1408	metallophosphoesterase
DKB62_RS08350	COG1279	arginine transmembrane transporter activity
DKB62_RS08355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DKB62_RS08370	COG1151	hydroxylamine reductase activity
DKB62_RS08375	COG1846	Transcriptional regulator
DKB62_RS08380	COG2814	Major facilitator Superfamily
DKB62_RS08390	COG2827	Endonuclease containing a URI domain
DKB62_RS08405	COG1733	regulation of RNA biosynthetic process
DKB62_RS08470	COG0657	acetylesterase activity
DKB62_RS08485	COG2390	Transcriptional regulator
DKB62_RS08490	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DKB62_RS08495	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DKB62_RS08500	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DKB62_RS08505	COG3634	alkyl hydroperoxide reductase activity
DKB62_RS08530	COG1045	serine acetyltransferase
DKB62_RS08560	COG0644	oxidoreductase
DKB62_RS08565	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
DKB62_RS08575	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DKB62_RS08580	COG0564	pseudouridine synthase activity
DKB62_RS08585	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DKB62_RS08595	COG2814	Major facilitator Superfamily
DKB62_RS08635	COG2376	Dihydroxyacetone kinase
DKB62_RS08645	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DKB62_RS08645	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DKB62_RS08645	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKB62_RS08650	COG1073	alpha beta
DKB62_RS08685	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DKB62_RS08690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DKB62_RS08695	COG0406	alpha-ribazole phosphatase activity
DKB62_RS08700	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DKB62_RS08720	COG3464	Transposase
DKB62_RS08725	COG1494	fructose-1,6-bisphosphatase
DKB62_RS08740	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DKB62_RS08745	COG1077	Cell shape determining protein MreB Mrl
DKB62_RS08755	COG0750	zinc metalloprotease
DKB62_RS08765	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DKB62_RS08780	COG1674	ftsk spoiiie
DKB62_RS08785	COG1426	Protein conserved in bacteria
DKB62_RS08795	COG1840	ABC-type Fe3 transport system, periplasmic component
DKB62_RS08805	COG1546	Belongs to the CinA family
DKB62_RS08805	COG1058	Belongs to the CinA family
DKB62_RS08810	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DKB62_RS08815	COG2137	regulation of response to DNA damage stimulus
DKB62_RS08820	COG1418	mRNA catabolic process
DKB62_RS08850	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DKB62_RS08855	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DKB62_RS08860	COG1187	pseudouridine synthase activity
DKB62_RS08865	COG2081	HI0933 family
DKB62_RS08870	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DKB62_RS08880	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DKB62_RS08880	COG0539	negative regulation of cytoplasmic translation
DKB62_RS08890	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DKB62_RS08895	COG0742	ribosomal rna small subunit methyltransferase
DKB62_RS08900	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DKB62_RS08910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DKB62_RS08915	COG1691	(AIR) carboxylase
DKB62_RS08925	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DKB62_RS08930	COG3394	polysaccharide catabolic process
DKB62_RS08935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DKB62_RS08940	COG4492	Belongs to the UPF0735 family
DKB62_RS08945	COG0460	homoserine dehydrogenase
DKB62_RS08950	COG0083	homoserine kinase activity
DKB62_RS08970	COG0525	valine-tRNA ligase activity
DKB62_RS08990	COG4499	WXG100 protein secretion system (Wss), protein YukC
DKB62_RS08990	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DKB62_RS08995	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DKB62_RS09000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DKB62_RS09005	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DKB62_RS09015	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DKB62_RS09020	COG1132	(ABC) transporter
DKB62_RS09025	COG1519	Transferase
DKB62_RS09030	COG1663	tetraacyldisaccharide 4'-kinase activity
DKB62_RS09035	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DKB62_RS09040	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DKB62_RS09050	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DKB62_RS09070	COG1137	ATPase activity
DKB62_RS09080	COG4372	Transposase
DKB62_RS09090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DKB62_RS09100	COG2030	dehydratase
DKB62_RS09105	COG0416	fatty acid biosynthetic process
DKB62_RS09110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DKB62_RS09115	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DKB62_RS09120	COG1028	Short-chain dehydrogenase reductase Sdr
DKB62_RS09125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DKB62_RS09135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DKB62_RS09140	COG0571	ribonuclease III activity
DKB62_RS09150	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DKB62_RS09160	COG0583	DNA-binding transcription factor activity
DKB62_RS09165	COG0573	inorganic phosphate transmembrane transporter activity
DKB62_RS09170	COG0581	inorganic phosphate transmembrane transporter activity
DKB62_RS09175	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DKB62_RS09190	COG0626	cystathionine gamma-synthase activity
DKB62_RS09195	COG1757	Na H antiporter
DKB62_RS09205	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DKB62_RS09210	COG0732	type I restriction modification DNA specificity domain
DKB62_RS09220	COG4974	Belongs to the 'phage' integrase family
DKB62_RS09235	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DKB62_RS09240	COG1715	Restriction endonuclease
DKB62_RS09245	COG0519	Catalyzes the synthesis of GMP from XMP
DKB62_RS09255	COG3328	transposase activity
DKB62_RS09295	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DKB62_RS09325	COG0589	response to stress
DKB62_RS09370	COG0018	arginyl-trna synthetase
DKB62_RS09375	COG0504	CTP synthase activity
DKB62_RS09385	COG4656	Part of a membrane complex involved in electron transport
DKB62_RS09390	COG4658	electron transport chain
DKB62_RS09395	COG4659	FMN binding
DKB62_RS09400	COG4660	Part of a membrane complex involved in electron transport
DKB62_RS09405	COG4657	Part of a membrane complex involved in electron transport
DKB62_RS09410	COG1148	4fe-4S ferredoxin, iron-sulfur binding domain protein
DKB62_RS09410	COG2878	Part of a membrane complex involved in electron transport
DKB62_RS09415	COG1477	protein flavinylation
DKB62_RS09420	COG1522	sequence-specific DNA binding
DKB62_RS09430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DKB62_RS09435	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DKB62_RS09435	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DKB62_RS09440	COG0277	FAD linked oxidase domain protein
DKB62_RS09450	COG1098	S1 RNA binding domain
DKB62_RS09460	COG0037	tRNA processing
DKB62_RS09465	COG0037	tRNA processing
DKB62_RS09465	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DKB62_RS09470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DKB62_RS09485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DKB62_RS09540	COG1122	ATPase activity
DKB62_RS09545	COG1122	ATPase activity
DKB62_RS09550	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DKB62_RS09555	COG0101	tRNA pseudouridine synthase activity
DKB62_RS09580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DKB62_RS09585	COG1115	amino acid carrier protein
DKB62_RS09590	COG1473	amidohydrolase
DKB62_RS09605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DKB62_RS09605	COG4651	solute:proton antiporter activity
DKB62_RS09615	COG1592	Rubrerythrin
DKB62_RS09615	COG1773	rubredoxin
DKB62_RS09630	COG0745	RESPONSE REGULATOR receiver
DKB62_RS09635	COG5002	protein histidine kinase activity
DKB62_RS09640	COG3875	lactate racemase activity
DKB62_RS09645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DKB62_RS09650	COG0573	inorganic phosphate transmembrane transporter activity
DKB62_RS09655	COG0581	inorganic phosphate transmembrane transporter activity
DKB62_RS09660	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DKB62_RS09665	COG0704	Plays a role in the regulation of phosphate uptake
DKB62_RS09675	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DKB62_RS09690	COG1620	l-lactate permease
DKB62_RS09695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DKB62_RS09700	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DKB62_RS09705	COG1802	Transcriptional regulator
DKB62_RS09710	COG3875	lactate racemase activity
DKB62_RS09715	COG0277	FAD linked oxidase domain protein
DKB62_RS09740	COG2031	fatty acid transporter
DKB62_RS09745	COG4974	Belongs to the 'phage' integrase family
DKB62_RS09760	COG2826	transposase and inactivated derivatives, IS30 family
DKB62_RS09810	COG5377	YqaJ viral recombinase family
DKB62_RS09820	COG3723	Recombinational DNA repair protein, rece pathway
DKB62_RS09840	COG3935	DnaD domain protein
DKB62_RS09870	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
DKB62_RS10045	COG4974	Belongs to the 'phage' integrase family
DKB62_RS10055	COG4824	toxin secretion phage lysis holin
DKB62_RS10095	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DKB62_RS10115	COG2160	L-arabinose isomerase activity
DKB62_RS10120	COG1609	Transcriptional regulator
DKB62_RS10125	COG2017	converts alpha-aldose to the beta-anomer
DKB62_RS10140	COG0521	Mo-molybdopterin cofactor biosynthetic process
DKB62_RS10145	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
DKB62_RS10150	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DKB62_RS10155	COG0406	alpha-ribazole phosphatase activity
DKB62_RS10160	COG1187	pseudouridine synthase activity
DKB62_RS10170	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DKB62_RS10185	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DKB62_RS10190	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DKB62_RS10195	COG1570	exodeoxyribonuclease VII activity
DKB62_RS10210	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DKB62_RS10215	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DKB62_RS10220	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DKB62_RS10225	COG1438	arginine binding
DKB62_RS10230	COG0497	DNA recombination
DKB62_RS10240	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DKB62_RS10245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DKB62_RS10265	COG2226	methyltransferase
DKB62_RS10265	COG1073	alpha beta
DKB62_RS10270	COG0601	transmembrane transport
DKB62_RS10275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DKB62_RS10285	COG0444	Belongs to the ABC transporter superfamily
DKB62_RS10315	COG0531	amino acid
DKB62_RS10320	COG0183	Belongs to the thiolase family
DKB62_RS10330	COG1268	BioY protein
DKB62_RS10340	COG0318	PFAM AMP-dependent synthetase and ligase
DKB62_RS10345	COG0813	purine-nucleoside phosphorylase activity
DKB62_RS10365	COG2223	nitrite transmembrane transporter activity
DKB62_RS10370	COG0436	Aminotransferase
DKB62_RS10385	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DKB62_RS10390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DKB62_RS10395	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DKB62_RS10400	COG0617	tRNA 3'-terminal CCA addition
DKB62_RS10400	COG0517	IMP dehydrogenase activity
DKB62_RS10400	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DKB62_RS10405	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DKB62_RS10405	COG0519	Catalyzes the synthesis of GMP from XMP
DKB62_RS10410	COG0582	viral genome integration into host DNA
DKB62_RS10440	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DKB62_RS10455	COG3177	Filamentation induced by cAMP protein fic
DKB62_RS10465	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DKB62_RS10480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DKB62_RS10485	COG1113	amino acid transport
DKB62_RS10490	COG0251	oxidation-reduction process
DKB62_RS10500	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DKB62_RS10535	COG0138	bifunctional purine biosynthesis protein purh
DKB62_RS10540	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
DKB62_RS10545	COG2826	transposase and inactivated derivatives, IS30 family
DKB62_RS10555	COG0833	amino acid
DKB62_RS10565	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DKB62_RS10570	COG1144	Oxidoreductase
DKB62_RS10590	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DKB62_RS10595	COG1040	competence protein
DKB62_RS10610	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DKB62_RS10620	COG0157	Belongs to the NadC ModD family
DKB62_RS10640	COG0786	glutamate:sodium symporter activity
DKB62_RS10645	COG1323	Belongs to the UPF0348 family
DKB62_RS10665	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DKB62_RS10670	COG4956	integral membrane protein (PIN domain superfamily)
DKB62_RS10675	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DKB62_RS10675	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DKB62_RS10680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DKB62_RS10685	COG0215	cysteine-tRNA ligase activity
DKB62_RS10690	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DKB62_RS10695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DKB62_RS10700	COG3688	RNA-binding protein containing a PIN domain
DKB62_RS10715	COG0557	exoribonuclease II activity
DKB62_RS10720	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DKB62_RS10725	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
DKB62_RS10730	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DKB62_RS10740	COG3639	organic phosphonate transmembrane transporter activity
DKB62_RS10745	COG1454	alcohol dehydrogenase
DKB62_RS10750	COG0590	tRNA wobble adenosine to inosine editing
DKB62_RS10765	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DKB62_RS10770	COG0237	dephospho-CoA kinase activity
DKB62_RS10790	COG0779	Required for maturation of 30S ribosomal subunits
DKB62_RS10795	COG0195	Participates in both transcription termination and antitermination
DKB62_RS10800	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DKB62_RS10810	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DKB62_RS10815	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DKB62_RS10825	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DKB62_RS10830	COG0196	riboflavin kinase activity
DKB62_RS10835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DKB62_RS10840	COG3959	Transketolase, thiamine diphosphate binding domain
DKB62_RS10845	COG3958	Transketolase
DKB62_RS10855	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DKB62_RS10865	COG1606	tRNA processing
DKB62_RS10870	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DKB62_RS10885	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DKB62_RS10895	COG0396	ATPase activity
DKB62_RS10910	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DKB62_RS10915	COG0822	iron-sulfur transferase activity
DKB62_RS10940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DKB62_RS10945	COG0514	ATP-dependent DNA helicase (RecQ)
DKB62_RS10950	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DKB62_RS10965	COG1278	Cold shock
DKB62_RS10975	COG0346	lactoylglutathione lyase activity
DKB62_RS10980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DKB62_RS10985	COG1739	Uncharacterized protein family UPF0029
DKB62_RS10995	COG1362	aminopeptidase activity
DKB62_RS11000	COG1113	amino acid transport
DKB62_RS11005	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DKB62_RS11010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DKB62_RS11015	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DKB62_RS11020	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DKB62_RS11025	COG2136	Putative SAM-dependent methyltransferase
DKB62_RS11025	COG2521	methyltransferase
DKB62_RS11030	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DKB62_RS11035	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DKB62_RS11045	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DKB62_RS11060	COG0826	peptidase U32
DKB62_RS11065	COG1193	negative regulation of DNA recombination
DKB62_RS11085	COG3328	transposase activity
DKB62_RS11090	COG0515	serine threonine protein kinase
DKB62_RS11095	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DKB62_RS11105	COG1115	amino acid carrier protein
DKB62_RS11120	COG0243	molybdopterin cofactor binding
DKB62_RS11130	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DKB62_RS11150	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DKB62_RS11155	COG0336	Belongs to the RNA methyltransferase TrmD family
DKB62_RS11160	COG4752	Belongs to the RNA methyltransferase TrmD family
DKB62_RS11165	COG0217	transcriptional regulatory protein
DKB62_RS11215	COG2826	transposase and inactivated derivatives, IS30 family
DKB62_RS11220	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DKB62_RS11230	COG3959	Transketolase, thiamine diphosphate binding domain
DKB62_RS11235	COG3958	Transketolase
DKB62_RS11250	COG1216	Glycosyl transferase, family 2
DKB62_RS11255	COG0562	UDP-galactopyranose mutase
DKB62_RS11260	COG2826	transposase and inactivated derivatives, IS30 family
DKB62_RS11290	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DKB62_RS11295	COG0488	(ABC) transporter
DKB62_RS11310	COG3206	protein involved in exopolysaccharide biosynthesis
DKB62_RS11315	COG3206	protein involved in exopolysaccharide biosynthesis
DKB62_RS11325	COG2826	transposase and inactivated derivatives, IS30 family
DKB62_RS11330	COG3206	protein involved in exopolysaccharide biosynthesis
DKB62_RS11345	COG0463	Glycosyl transferase, family 2
DKB62_RS11350	COG1442	glycosyl transferase family 8
DKB62_RS11365	COG1216	Glycosyl transferase, family 2
DKB62_RS11380	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DKB62_RS11395	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DKB62_RS11415	COG0495	leucyl-tRNA aminoacylation
DKB62_RS11455	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DKB62_RS11475	COG1196	nuclear chromosome segregation
DKB62_RS11480	COG0552	protein localization to endoplasmic reticulum
DKB62_RS11495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DKB62_RS11505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DKB62_RS11505	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DKB62_RS11515	COG1242	4 iron, 4 sulfur cluster binding
DKB62_RS11520	COG1702	phosphate starvation-inducible protein PhoH
DKB62_RS11540	COG1253	flavin adenine dinucleotide binding
DKB62_RS11550	COG0534	Mate efflux family protein
DKB62_RS11565	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DKB62_RS11570	COG0653	protein targeting
DKB62_RS11575	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DKB62_RS11595	COG2884	Cell division ATP-binding protein ftsE
DKB62_RS11600	COG2177	Part of the ABC transporter FtsEX involved in
DKB62_RS11605	COG4942	peptidase
DKB62_RS11610	COG0793	Belongs to the peptidase S41A family
DKB62_RS11610	COG3409	Peptidoglycan-binding domain 1 protein
DKB62_RS11615	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DKB62_RS11625	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DKB62_RS11630	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DKB62_RS11635	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DKB62_RS11640	COG1713	HD superfamily hydrolase involved in NAD metabolism
DKB62_RS11650	COG0799	negative regulation of ribosome biogenesis
DKB62_RS11655	COG2996	Protein conserved in bacteria
DKB62_RS11660	COG1077	Cell shape determining protein MreB Mrl
DKB62_RS11665	COG1792	Involved in formation and maintenance of cell shape
DKB62_RS11675	COG0768	penicillin binding
DKB62_RS11680	COG2894	cell division
DKB62_RS11685	COG0772	Belongs to the SEDS family
DKB62_RS11710	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DKB62_RS11715	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DKB62_RS11720	COG0066	3-isopropylmalate dehydratase activity
DKB62_RS11730	COG0583	DNA-binding transcription factor activity
DKB62_RS11735	COG2855	membrane
DKB62_RS11755	COG3328	transposase activity
DKB62_RS11775	COG1196	nuclear chromosome segregation
DKB62_RS11780	COG5295	Hep Hag repeat protein
DKB62_RS11785	COG1196	nuclear chromosome segregation
DKB62_RS11830	COG0583	DNA-binding transcription factor activity
DKB62_RS11840	COG1250	3-hydroxyacyl-CoA dehydrogenase
DKB62_RS11845	COG1024	Enoyl-CoA hydratase
DKB62_RS11850	COG0513	Belongs to the DEAD box helicase family
DKB62_RS11860	COG0110	maltose O-acetyltransferase activity
DKB62_RS11870	COG2011	ABC-type metal ion transport system permease component
DKB62_RS11875	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DKB62_RS11880	COG2205	protein histidine kinase activity
DKB62_RS11885	COG0745	RESPONSE REGULATOR receiver
DKB62_RS11895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DKB62_RS11900	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DKB62_RS11905	COG1968	undecaprenyl-diphosphatase activity
DKB62_RS11915	COG0732	type I restriction modification DNA specificity domain
DKB62_RS11935	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DKB62_RS11940	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DKB62_RS11945	COG1185	polyribonucleotide nucleotidyltransferase activity
DKB62_RS11950	COG0756	dUTP diphosphatase activity
DKB62_RS11955	COG0494	nUDIX hydrolase
DKB62_RS11960	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DKB62_RS11965	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DKB62_RS11995	COG3328	transposase activity
DKB62_RS12015	COG1420	regulation of RNA biosynthetic process
DKB62_RS12020	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DKB62_RS12030	COG0484	heat shock protein binding
DKB62_RS12035	COG2264	protein methyltransferase activity
DKB62_RS12040	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DKB62_RS12045	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DKB62_RS12050	COG0537	adenosine 5'-monophosphoramidase activity
DKB62_RS12080	COG3328	transposase activity
DKB62_RS12090	COG2826	transposase and inactivated derivatives, IS30 family
DKB62_RS12100	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DKB62_RS12105	COG0726	polysaccharide deacetylase
DKB62_RS12110	COG0110	maltose O-acetyltransferase activity
DKB62_RS12115	COG5002	protein histidine kinase activity
DKB62_RS12120	COG0745	RESPONSE REGULATOR receiver
DKB62_RS12125	COG0758	DNA mediated transformation
DKB62_RS12135	COG0792	nuclease activity
DKB62_RS12150	COG0702	epimerase
DKB62_RS12180	COG2384	SAM-dependent methyltransferase
DKB62_RS12185	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DKB62_RS12190	COG0352	thiamine-phosphate diphosphorylase activity
DKB62_RS12200	COG0527	aspartate kinase activity
DKB62_RS12215	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DKB62_RS12215	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DKB62_RS12220	COG0658	competence protein
DKB62_RS12220	COG2333	competence protein COMEC
DKB62_RS12230	COG0860	N-Acetylmuramoyl-L-alanine amidase
DKB62_RS12265	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DKB62_RS12270	COG2826	transposase and inactivated derivatives, IS30 family
DKB62_RS12275	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DKB62_RS12280	COG0154	amidase activity
DKB62_RS12285	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DKB62_RS12290	COG0519	Catalyzes the synthesis of GMP from XMP
DKB62_RS12295	COG2252	PERMEase
DKB62_RS12310	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DKB62_RS12335	COG2720	vancomycin resistance protein
DKB62_RS12340	COG2176	DNA-directed DNA polymerase activity
DKB62_RS12345	COG4496	protein, YerC YecD
DKB62_RS12355	COG2826	transposase and inactivated derivatives, IS30 family
DKB62_RS12365	COG1196	nuclear chromosome segregation
DKB62_RS12400	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DKB62_RS12405	COG2610	gluconate transmembrane transporter activity
DKB62_RS12410	COG1737	Transcriptional regulator
DKB62_RS12420	COG1530	ribonuclease E activity
DKB62_RS12425	COG2968	Membrane
DKB62_RS12430	COG0590	tRNA wobble adenosine to inosine editing
DKB62_RS12435	COG2860	membrane