locus-tag	class	description
MESAU_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MESAU_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MESAU_RS00035	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MESAU_RS00055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MESAU_RS00065	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MESAU_RS00070	COG5001	Diguanylate cyclase
MESAU_RS00070	COG3300	MHYT domain
MESAU_RS00075	COG2813	Specifically methylates the guanine in position
MESAU_RS00080	COG1185	polyribonucleotide nucleotidyltransferase activity
MESAU_RS00085	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MESAU_RS00090	COG0598	Magnesium transport protein CorA
MESAU_RS00095	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MESAU_RS00100	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MESAU_RS00105	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MESAU_RS00120	COG0779	Required for maturation of 30S ribosomal subunits
MESAU_RS00130	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MESAU_RS00135	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MESAU_RS00140	COG1396	sequence-specific DNA binding
MESAU_RS00145	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MESAU_RS00160	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MESAU_RS00165	COG1702	phosphate starvation-inducible protein PhoH
MESAU_RS00170	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MESAU_RS00185	COG1214	PFAM Peptidase M22, glycoprotease
MESAU_RS00195	COG3487	Iron-regulated protein
MESAU_RS00225	COG3609	addiction module antidote protein, CC2985 family
MESAU_RS00230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MESAU_RS00235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MESAU_RS00245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MESAU_RS00255	COG0444	Belongs to the ABC transporter superfamily
MESAU_RS00260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MESAU_RS00265	COG0601	transmembrane transport
MESAU_RS00275	COG2951	lytic endotransglycosylase activity
MESAU_RS00280	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MESAU_RS00295	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MESAU_RS00300	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MESAU_RS00310	COG2816	NAD+ diphosphatase activity
MESAU_RS00320	COG1605	Chorismate mutase
MESAU_RS00320	COG0077	Prephenate dehydratase
MESAU_RS00325	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MESAU_RS00330	COG3474	cytochrome
MESAU_RS00335	COG4166	transmembrane transport
MESAU_RS00345	COG4174	ABC transporter (Permease)
MESAU_RS00350	COG4239	(ABC) transporter, permease
MESAU_RS00355	COG4172	Belongs to the ABC transporter superfamily
MESAU_RS00385	COG1793	dna ligase
MESAU_RS00420	COG1595	DNA-templated transcription, initiation
MESAU_RS00475	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MESAU_RS00490	COG0601	transmembrane transport
MESAU_RS00495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MESAU_RS00500	COG0444	Belongs to the ABC transporter superfamily
MESAU_RS00530	COG1024	Enoyl-CoA hydratase
MESAU_RS00535	COG1960	acyl-CoA dehydrogenase activity
MESAU_RS00540	COG0251	oxidation-reduction process
MESAU_RS00545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MESAU_RS00555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MESAU_RS00560	COG0765	amino acid transport
MESAU_RS00565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MESAU_RS00570	COG4608	Belongs to the ABC transporter superfamily
MESAU_RS00575	COG0444	Belongs to the ABC transporter superfamily
MESAU_RS00580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MESAU_RS00585	COG0601	transmembrane transport
MESAU_RS00590	COG0747	negative chemotaxis
MESAU_RS00605	COG0546	phosphoglycolate phosphatase activity
MESAU_RS00610	COG0166	Belongs to the GPI family
MESAU_RS00615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MESAU_RS00645	COG0129	dihydroxy-acid dehydratase activity
MESAU_RS00655	COG0489	protein tyrosine kinase activity
MESAU_RS00665	COG0583	DNA-binding transcription factor activity
MESAU_RS00680	COG3383	formate dehydrogenase (NAD+) activity
MESAU_RS00685	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MESAU_RS00695	COG2197	response regulator
MESAU_RS00720	COG1177	transmembrane transport
MESAU_RS00725	COG1176	ABC-type spermidine putrescine transport system, permease component I
MESAU_RS00730	COG3842	ATPase activity
MESAU_RS00735	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MESAU_RS00750	COG0583	DNA-binding transcription factor activity
MESAU_RS00755	COG0586	Pfam SNARE associated Golgi protein
MESAU_RS00760	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MESAU_RS00775	COG1959	2 iron, 2 sulfur cluster binding
MESAU_RS00780	COG0492	ferredoxin-NADP+ reductase activity
MESAU_RS00785	COG1349	DNA-binding transcription factor activity
MESAU_RS00800	COG2226	methyltransferase
MESAU_RS00810	COG0697	spore germination
MESAU_RS00815	COG0402	S-adenosylhomocysteine deaminase activity
MESAU_RS00820	COG1132	(ABC) transporter
MESAU_RS00825	COG0129	dihydroxy-acid dehydratase activity
MESAU_RS00835	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MESAU_RS00840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MESAU_RS00845	COG0121	glutamine amidotransferase
MESAU_RS00855	COG1522	sequence-specific DNA binding
MESAU_RS00860	COG0756	dUTP diphosphatase activity
MESAU_RS00865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MESAU_RS00875	COG3938	Belongs to the proline racemase family
MESAU_RS00890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MESAU_RS00900	COG0281	malic enzyme
MESAU_RS00900	COG0280	phosphate acetyltransferase
MESAU_RS00910	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MESAU_RS00915	COG0656	L-ascorbic acid biosynthetic process
MESAU_RS00940	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MESAU_RS00945	COG0728	peptidoglycan biosynthetic process
MESAU_RS00950	COG0180	Tryptophanyl-tRNA synthetase
MESAU_RS00960	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MESAU_RS00965	COG1388	LysM domain
MESAU_RS00965	COG1376	ErfK ybiS ycfS ynhG family protein
MESAU_RS01005	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MESAU_RS01010	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
MESAU_RS01020	COG1643	Atp-dependent helicase
MESAU_RS01040	COG1175	transmembrane transport
MESAU_RS01060	COG3842	ATPase activity
MESAU_RS01070	COG1461	Dihydroxyacetone kinase
MESAU_RS01085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MESAU_RS01095	COG2376	Dihydroxyacetone kinase
MESAU_RS01130	COG3206	protein involved in exopolysaccharide biosynthesis
MESAU_RS01130	COG0489	protein tyrosine kinase activity
MESAU_RS01135	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MESAU_RS01140	COG1215	transferase activity, transferring glycosyl groups
MESAU_RS01145	COG1215	transferase activity, transferring glycosyl groups
MESAU_RS01150	COG1215	transferase activity, transferring glycosyl groups
MESAU_RS01155	COG0438	transferase activity, transferring glycosyl groups
MESAU_RS01160	COG2244	polysaccharide biosynthetic process
MESAU_RS01165	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MESAU_RS01190	COG2273	Hydrolase Family 16
MESAU_RS01200	COG1215	transferase activity, transferring glycosyl groups
MESAU_RS01225	COG0367	asparagine synthase
MESAU_RS01235	COG1132	(ABC) transporter
MESAU_RS01250	COG1596	polysaccharide export
MESAU_RS01255	COG3307	-O-antigen
MESAU_RS01265	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS01295	COG1012	belongs to the aldehyde dehydrogenase family
MESAU_RS01350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MESAU_RS01385	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MESAU_RS01390	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MESAU_RS01395	COG0539	negative regulation of cytoplasmic translation
MESAU_RS01415	COG1309	transcriptional regulator
MESAU_RS01435	COG4215	(ABC) transporter
MESAU_RS01445	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MESAU_RS01505	COG5001	Diguanylate cyclase
MESAU_RS01535	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MESAU_RS01540	COG1063	alcohol dehydrogenase
MESAU_RS01545	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MESAU_RS01550	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MESAU_RS01560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MESAU_RS01565	COG1609	Transcriptional regulator
MESAU_RS01590	COG0523	cobalamin synthesis protein
MESAU_RS01620	COG0174	glutamine synthetase
MESAU_RS01630	COG1573	uracil-dna glycosylase
MESAU_RS01640	COG4702	Belongs to the UPF0303 family
MESAU_RS01645	COG0402	S-adenosylhomocysteine deaminase activity
MESAU_RS01655	COG0583	DNA-binding transcription factor activity
MESAU_RS01675	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MESAU_RS01685	COG2351	hydroxyisourate hydrolase activity
MESAU_RS01695	COG3257	ureidoglycine aminohydrolase activity
MESAU_RS01700	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
MESAU_RS01715	COG2944	sequence-specific DNA binding
MESAU_RS01725	COG4166	transmembrane transport
MESAU_RS01730	COG0601	transmembrane transport
MESAU_RS01735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MESAU_RS01745	COG4166	transmembrane transport
MESAU_RS01755	COG1595	DNA-templated transcription, initiation
MESAU_RS01765	COG1404	Belongs to the peptidase S8 family
MESAU_RS01780	COG1609	Transcriptional regulator
MESAU_RS01785	COG1653	transport
MESAU_RS01790	COG1175	transmembrane transport
MESAU_RS01795	COG0395	ABC-type sugar transport system, permease component
MESAU_RS01800	COG0366	Alpha amylase catalytic
MESAU_RS01805	COG3842	ATPase activity
MESAU_RS01835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MESAU_RS01850	COG1216	Glycosyl transferase, family 2
MESAU_RS01850	COG1442	glycosyl transferase family 8
MESAU_RS01870	COG4774	siderophore transport
MESAU_RS01875	COG1652	LysM domain
MESAU_RS01890	COG0300	oxidoreductase activity
MESAU_RS01895	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MESAU_RS01900	COG0745	RESPONSE REGULATOR receiver
MESAU_RS01905	COG2205	protein histidine kinase activity
MESAU_RS01910	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MESAU_RS01915	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
MESAU_RS01915	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MESAU_RS01925	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MESAU_RS01930	COG2205	protein histidine kinase activity
MESAU_RS01940	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MESAU_RS01945	COG2887	Belongs to the helicase family. UvrD subfamily
MESAU_RS01970	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MESAU_RS01975	COG0159	tryptophan synthase activity
MESAU_RS01980	COG0133	tryptophan synthase activity
MESAU_RS01985	COG0135	phosphoribosylanthranilate isomerase activity
MESAU_RS02005	COG3135	benzoate transporter
MESAU_RS02015	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MESAU_RS02025	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MESAU_RS02030	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MESAU_RS02035	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MESAU_RS02040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MESAU_RS02040	COG0072	phenylalanine-tRNA ligase activity
MESAU_RS02050	COG0667	Aldo Keto reductase
MESAU_RS02085	COG4191	Histidine kinase
MESAU_RS02090	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MESAU_RS02095	COG0594	ribonuclease P activity
MESAU_RS02100	COG0706	membrane insertase activity
MESAU_RS02110	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MESAU_RS02115	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
MESAU_RS02125	COG1566	PFAM secretion protein HlyD family protein
MESAU_RS02145	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MESAU_RS02165	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MESAU_RS02170	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
MESAU_RS02195	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MESAU_RS02200	COG1032	radical SAM domain protein
MESAU_RS02205	COG1522	sequence-specific DNA binding
MESAU_RS02210	COG3186	Phenylalanine-4-hydroxylase
MESAU_RS02230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MESAU_RS02235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MESAU_RS02240	COG0765	amino acid transport
MESAU_RS02260	COG3706	GGDEF domain
MESAU_RS02275	COG2171	N-acyltransferase activity
MESAU_RS02295	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MESAU_RS02300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MESAU_RS02310	COG0101	tRNA pseudouridine synthase activity
MESAU_RS02320	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MESAU_RS02325	COG0242	peptide deformylase activity
MESAU_RS02350	COG2076	Multidrug Resistance protein
MESAU_RS02365	COG0628	permease
MESAU_RS02370	COG2162	N-hydroxyarylamine O-acetyltransferase activity
MESAU_RS02375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MESAU_RS02380	COG0483	inositol monophosphate 1-phosphatase activity
MESAU_RS02385	COG1609	Transcriptional regulator
MESAU_RS02390	COG1129	ABC transporter
MESAU_RS02395	COG1172	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS02400	COG1879	ABC-type sugar transport system periplasmic component
MESAU_RS02415	COG1846	Transcriptional regulator
MESAU_RS02440	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MESAU_RS02450	COG1335	isochorismatase
MESAU_RS02465	COG0411	ABC transporter
MESAU_RS02490	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MESAU_RS02495	COG0583	DNA-binding transcription factor activity
MESAU_RS02510	COG0765	amino acid transport
MESAU_RS02515	COG0765	amino acid transport
MESAU_RS02520	COG0604	alcohol dehydrogenase
MESAU_RS02525	COG0534	Mate efflux family protein
MESAU_RS02545	COG0395	ABC-type sugar transport system, permease component
MESAU_RS02550	COG1063	alcohol dehydrogenase
MESAU_RS02555	COG3842	ATPase activity
MESAU_RS02590	COG1175	transmembrane transport
MESAU_RS02600	COG0583	DNA-binding transcription factor activity
MESAU_RS02615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MESAU_RS02625	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MESAU_RS02635	COG0830	nickel cation binding
MESAU_RS02640	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MESAU_RS02645	COG0625	glutathione transferase activity
MESAU_RS02660	COG0804	urea catabolic process
MESAU_RS02675	COG0832	Belongs to the urease beta subunit family
MESAU_RS02685	COG3813	Protein conserved in bacteria
MESAU_RS02690	COG0831	urea catabolic process
MESAU_RS02695	COG0829	nickel cation binding
MESAU_RS02710	COG0625	glutathione transferase activity
MESAU_RS02720	COG1072	(Pantothenic acid kinase))
MESAU_RS02735	COG1686	Belongs to the peptidase S11 family
MESAU_RS02765	COG5489	Protein of unknown function (DUF736)
MESAU_RS02770	COG4957	zinc ion binding
MESAU_RS02820	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MESAU_RS02835	COG4974	Belongs to the 'phage' integrase family
MESAU_RS02845	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS02850	COG0640	Transcriptional regulator
MESAU_RS02860	COG2226	methyltransferase
MESAU_RS02865	COG1609	Transcriptional regulator
MESAU_RS02880	COG1172	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS02895	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
MESAU_RS02900	COG3454	Phosphonate metabolism
MESAU_RS02905	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
MESAU_RS02910	COG3718	enzyme involved in inositol metabolism
MESAU_RS02920	COG1082	Xylose isomerase domain protein TIM barrel
MESAU_RS02925	COG3962	Belongs to the TPP enzyme family
MESAU_RS02930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MESAU_RS02960	COG0640	Transcriptional regulator
MESAU_RS02965	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MESAU_RS02980	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS02985	COG0673	inositol 2-dehydrogenase activity
MESAU_RS02995	COG1172	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS03010	COG1609	Transcriptional regulator
MESAU_RS03035	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MESAU_RS03050	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MESAU_RS03055	COG0131	Imidazoleglycerol-phosphate dehydratase
MESAU_RS03065	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MESAU_RS03075	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MESAU_RS03085	COG0107	imidazoleglycerol-phosphate synthase activity
MESAU_RS03090	COG0140	phosphoribosyl-ATP diphosphatase activity
MESAU_RS03095	COG1072	(Pantothenic acid kinase))
MESAU_RS03110	COG0205	6-phosphofructokinase activity
MESAU_RS03115	COG1388	LysM domain
MESAU_RS03115	COG1376	ErfK ybiS ycfS ynhG family protein
MESAU_RS03125	COG1280	lysine exporter protein (LysE YggA)
MESAU_RS03140	COG1070	Carbohydrate kinase
MESAU_RS03150	COG2115	Belongs to the xylose isomerase family
MESAU_RS03160	COG4977	sequence-specific DNA binding
MESAU_RS03165	COG3246	L-lysine catabolic process to acetate
MESAU_RS03175	COG1250	3-hydroxyacyl-CoA dehydrogenase
MESAU_RS03210	COG3842	ATPase activity
MESAU_RS03215	COG1176	ABC-type spermidine putrescine transport system, permease component I
MESAU_RS03225	COG0405	Gamma-glutamyltransferase
MESAU_RS03230	COG0318	PFAM AMP-dependent synthetase and ligase
MESAU_RS03235	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MESAU_RS03290	COG0747	negative chemotaxis
MESAU_RS03300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MESAU_RS03325	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MESAU_RS03330	COG2011	ABC-type metal ion transport system permease component
MESAU_RS03345	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MESAU_RS03370	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MESAU_RS03375	COG1012	belongs to the aldehyde dehydrogenase family
MESAU_RS03380	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS03385	COG0179	Fumarylacetoacetate (FAA) hydrolase
MESAU_RS03395	COG0673	inositol 2-dehydrogenase activity
MESAU_RS03400	COG0395	ABC-type sugar transport system, permease component
MESAU_RS03405	COG1175	transmembrane transport
MESAU_RS03410	COG1653	transport
MESAU_RS03415	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MESAU_RS03420	COG2971	BadF BadG BcrA BcrD
MESAU_RS03425	COG2188	Transcriptional regulator
MESAU_RS03430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MESAU_RS03435	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MESAU_RS03440	COG0579	oxidoreductase
MESAU_RS03445	COG0318	PFAM AMP-dependent synthetase and ligase
MESAU_RS03470	COG0443	Heat shock 70 kDa protein
MESAU_RS03475	COG0484	heat shock protein binding
MESAU_RS03480	COG3963	phosphatidate phosphatase activity
MESAU_RS03490	COG0284	orotidine-5'-phosphate decarboxylase activity
MESAU_RS03505	COG3386	PFAM SMP-30 Gluconolaconase
MESAU_RS03510	COG0800	Aldolase
MESAU_RS03515	COG3734	2-keto-3-deoxy-galactonokinase
MESAU_RS03520	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS03525	COG5001	Diguanylate cyclase
MESAU_RS03540	COG0189	ligase activity
MESAU_RS03605	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MESAU_RS03610	COG0606	chelatase, subunit chli
MESAU_RS03620	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MESAU_RS03655	COG0076	glutamate decarboxylase activity
MESAU_RS03680	COG3634	alkyl hydroperoxide reductase activity
MESAU_RS03690	COG0588	phosphoglycerate mutase activity
MESAU_RS03695	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MESAU_RS03700	COG1132	(ABC) transporter
MESAU_RS03705	COG0837	glucose binding
MESAU_RS03710	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
MESAU_RS03720	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MESAU_RS03730	COG1968	undecaprenyl-diphosphatase activity
MESAU_RS03735	COG0792	nuclease activity
MESAU_RS03740	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MESAU_RS03755	COG0626	cystathionine gamma-synthase activity
MESAU_RS03770	COG1959	2 iron, 2 sulfur cluster binding
MESAU_RS03775	COG4521	taurine ABC transporter
MESAU_RS03780	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MESAU_RS03785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MESAU_RS03800	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MESAU_RS03840	COG3030	protein affecting phage T7 exclusion by the F plasmid
MESAU_RS03845	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
MESAU_RS03850	COG0747	negative chemotaxis
MESAU_RS03870	COG0481	GTPase activity
MESAU_RS03890	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MESAU_RS03895	COG1294	oxidase, subunit
MESAU_RS03900	COG1271	oxidase subunit
MESAU_RS03905	COG1131	(ABC) transporter
MESAU_RS03910	COG0842	Transport permease protein
MESAU_RS03925	COG3634	alkyl hydroperoxide reductase activity
MESAU_RS03945	COG2197	response regulator
MESAU_RS03960	COG0671	phosphoesterase, PA-phosphatase related
MESAU_RS03970	COG0659	secondary active sulfate transmembrane transporter activity
MESAU_RS03975	COG2094	Belongs to the DNA glycosylase MPG family
MESAU_RS03995	COG2954	triphosphatase activity
MESAU_RS04010	COG1131	(ABC) transporter
MESAU_RS04015	COG0842	Transport permease protein
MESAU_RS04015	COG1129	ABC transporter
MESAU_RS04060	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MESAU_RS04065	COG3685	Protein conserved in bacteria
MESAU_RS04080	COG2358	TRAP transporter, solute receptor (TAXI family
MESAU_RS04085	COG3795	YCII-related domain
MESAU_RS04090	COG4941	Belongs to the sigma-70 factor family
MESAU_RS04120	COG1420	regulation of RNA biosynthetic process
MESAU_RS04125	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MESAU_RS04135	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MESAU_RS04140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MESAU_RS04155	COG0006	proline dipeptidase activity
MESAU_RS04160	COG1335	isochorismatase
MESAU_RS04170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MESAU_RS04175	COG0237	dephospho-CoA kinase activity
MESAU_RS04180	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MESAU_RS04185	COG0424	maF-like protein
MESAU_RS04190	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MESAU_RS04195	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MESAU_RS04200	COG1981	membrane
MESAU_RS04205	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MESAU_RS04210	COG1331	Highly conserved protein containing a thioredoxin domain
MESAU_RS04215	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MESAU_RS04220	COG0445	tRNA wobble uridine modification
MESAU_RS04225	COG0357	Ribosomal RNA small subunit methyltransferase G
MESAU_RS04305	COG0251	oxidation-reduction process
MESAU_RS04310	COG3964	amidohydrolase
MESAU_RS04315	COG2072	flavoprotein involved in K transport
MESAU_RS04320	COG1737	Transcriptional regulator
MESAU_RS04325	COG1116	anion transmembrane transporter activity
MESAU_RS04340	COG0673	inositol 2-dehydrogenase activity
MESAU_RS04410	COG0582	viral genome integration into host DNA
MESAU_RS04420	COG4195	phage-related replication protein
MESAU_RS04485	COG0587	DNA-directed DNA polymerase activity
MESAU_RS04530	COG0717	Belongs to the dCTP deaminase family
MESAU_RS04555	COG3451	type IV secretory pathway VirB4
MESAU_RS04570	COG3846	protein secretion by the type IV secretion system
MESAU_RS04585	COG2948	multi-organism process
MESAU_RS04600	COG3916	Acyl-homoserine-lactone synthase
MESAU_RS04605	COG2197	response regulator
MESAU_RS04620	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MESAU_RS04630	COG3845	ABC transporter
MESAU_RS04635	COG4603	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS04640	COG1079	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS04645	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MESAU_RS04660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MESAU_RS04675	COG1079	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS04680	COG4603	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS04685	COG3845	ABC transporter
MESAU_RS04695	COG2186	Transcriptional regulator
MESAU_RS04715	COG0625	glutathione transferase activity
MESAU_RS04720	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MESAU_RS04725	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MESAU_RS04750	COG3118	belongs to the thioredoxin family
MESAU_RS04755	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MESAU_RS04760	COG2835	tetraacyldisaccharide 4'-kinase activity
MESAU_RS04765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MESAU_RS04775	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MESAU_RS04780	COG4133	protoheme IX ABC transporter activity
MESAU_RS04785	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MESAU_RS04800	COG3842	ATPase activity
MESAU_RS04810	COG1176	ABC-type spermidine putrescine transport system, permease component I
MESAU_RS04835	COG0670	Belongs to the BI1 family
MESAU_RS04840	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MESAU_RS04845	COG1136	(ABC) transporter
MESAU_RS04855	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MESAU_RS04865	COG2154	pterin-4-alpha-carbinolamine dehydratase
MESAU_RS04870	COG3339	Conserved Protein
MESAU_RS04895	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MESAU_RS04920	COG0137	argininosuccinate synthase activity
MESAU_RS04945	COG1266	CAAX protease self-immunity
MESAU_RS04950	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MESAU_RS04955	COG0287	Prephenate dehydrogenase
MESAU_RS04955	COG1605	Chorismate mutase
MESAU_RS04960	COG0228	four-way junction DNA binding
MESAU_RS04975	COG3781	membrane
MESAU_RS04985	COG0519	Catalyzes the synthesis of GMP from XMP
MESAU_RS04990	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MESAU_RS04995	COG0513	Belongs to the DEAD box helicase family
MESAU_RS05015	COG0473	3-isopropylmalate dehydrogenase activity
MESAU_RS05025	COG0251	oxidation-reduction process
MESAU_RS05030	COG1376	ErfK ybiS ycfS ynhG family protein
MESAU_RS05040	COG0066	3-isopropylmalate dehydratase activity
MESAU_RS05050	COG0640	Transcriptional regulator
MESAU_RS05065	COG1801	Protein of unknown function DUF72
MESAU_RS05075	COG2205	protein histidine kinase activity
MESAU_RS05080	COG0745	RESPONSE REGULATOR receiver
MESAU_RS05090	COG2301	Belongs to the HpcH HpaI aldolase family
MESAU_RS05125	COG0587	DNA-directed DNA polymerase activity
MESAU_RS05140	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MESAU_RS05170	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MESAU_RS05175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MESAU_RS05180	COG0552	protein localization to endoplasmic reticulum
MESAU_RS05185	COG2917	probably involved in intracellular septation
MESAU_RS05195	COG0431	NADPH-dependent FMN reductase
MESAU_RS05205	COG0039	L-malate dehydrogenase activity
MESAU_RS05210	COG0045	succinate-CoA ligase (ADP-forming) activity
MESAU_RS05225	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MESAU_RS05230	COG0567	Dehydrogenase, E1 component
MESAU_RS05235	COG0508	dehydrogenase complex catalyzes the overall conversion of
MESAU_RS05245	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS05260	COG4974	Belongs to the 'phage' integrase family
MESAU_RS05265	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MESAU_RS05270	COG0336	Belongs to the RNA methyltransferase TrmD family
MESAU_RS05280	COG0335	large ribosomal subunit rRNA binding
MESAU_RS05285	COG1764	response to oxidative stress
MESAU_RS05290	COG1846	Transcriptional regulator
MESAU_RS05300	COG0765	amino acid transport
MESAU_RS05310	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MESAU_RS05370	COG3132	Protein of unknown function, DUF480
MESAU_RS05375	COG1764	response to oxidative stress
MESAU_RS05385	COG3795	YCII-related domain
MESAU_RS05395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MESAU_RS05400	COG1946	Acyl-CoA thioesterase
MESAU_RS05405	COG0347	Belongs to the P(II) protein family
MESAU_RS05410	COG0004	ammonium transporteR
MESAU_RS05420	COG1674	ftsk spoiiie
MESAU_RS05420	COG2261	transglycosylase associated protein
MESAU_RS05425	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MESAU_RS05440	COG0745	RESPONSE REGULATOR receiver
MESAU_RS05455	COG0583	DNA-binding transcription factor activity
MESAU_RS05470	COG2264	protein methyltransferase activity
MESAU_RS05485	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MESAU_RS05490	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MESAU_RS05495	COG0181	hydroxymethylbilane synthase activity
MESAU_RS05520	COG0519	Catalyzes the synthesis of GMP from XMP
MESAU_RS05520	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MESAU_RS05540	COG4957	zinc ion binding
MESAU_RS05555	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
MESAU_RS05565	COG1879	ABC-type sugar transport system periplasmic component
MESAU_RS05570	COG1129	ABC transporter
MESAU_RS05580	COG1172	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS05585	COG1024	Enoyl-CoA hydratase
MESAU_RS05585	COG1250	3-hydroxyacyl-CoA dehydrogenase
MESAU_RS05590	COG2197	response regulator
MESAU_RS05595	COG3842	ATPase activity
MESAU_RS05600	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MESAU_RS05605	COG1176	ABC-type spermidine putrescine transport system, permease component I
MESAU_RS05610	COG1177	transmembrane transport
MESAU_RS05640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MESAU_RS05645	COG1414	Transcriptional regulator
MESAU_RS05650	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MESAU_RS05655	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MESAU_RS05660	COG0183	Belongs to the thiolase family
MESAU_RS05670	COG3845	ABC transporter
MESAU_RS05675	COG4603	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS05680	COG1079	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS05690	COG1335	isochorismatase
MESAU_RS05695	COG1120	ATPase activity
MESAU_RS05705	COG0848	biopolymer transport protein
MESAU_RS05710	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MESAU_RS05740	COG1872	DUF167
MESAU_RS05745	COG1737	Transcriptional regulator
MESAU_RS05770	COG0395	ABC-type sugar transport system, permease component
MESAU_RS05800	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
MESAU_RS05810	COG1704	LemA family
MESAU_RS05815	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MESAU_RS05820	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MESAU_RS05830	COG1247	-acetyltransferase
MESAU_RS05835	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MESAU_RS05845	COG1309	transcriptional regulator
MESAU_RS05850	COG2271	Major facilitator Superfamily
MESAU_RS05860	COG1217	gtp-binding protein TYPA
MESAU_RS05875	COG2986	histidine ammonia-lyase
MESAU_RS05890	COG2270	Major facilitator Superfamily
MESAU_RS05895	COG0138	bifunctional purine biosynthesis protein purh
MESAU_RS05910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MESAU_RS05910	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MESAU_RS05915	COG0501	Belongs to the peptidase M48B family
MESAU_RS05925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MESAU_RS05940	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MESAU_RS05950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MESAU_RS05955	COG5425	PFAM Usg family protein
MESAU_RS05960	COG0667	Aldo Keto reductase
MESAU_RS05965	COG2814	Major facilitator Superfamily
MESAU_RS05970	COG0583	DNA-binding transcription factor activity
MESAU_RS05975	COG0667	Aldo Keto reductase
MESAU_RS05980	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MESAU_RS05985	COG0495	leucyl-tRNA aminoacylation
MESAU_RS06000	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MESAU_RS06020	COG1794	racemase activity, acting on amino acids and derivatives
MESAU_RS06030	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MESAU_RS06035	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MESAU_RS06040	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MESAU_RS06045	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MESAU_RS06050	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MESAU_RS06055	COG0246	Mannitol dehydrogenase
MESAU_RS06060	COG1904	glucuronate isomerase
MESAU_RS06065	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MESAU_RS06070	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MESAU_RS06080	COG2186	Transcriptional regulator
MESAU_RS06085	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MESAU_RS06090	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS06105	COG0514	ATP-dependent DNA helicase (RecQ)
MESAU_RS06110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MESAU_RS06130	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MESAU_RS06130	COG3743	rRNA binding
MESAU_RS06135	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MESAU_RS06140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MESAU_RS06150	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MESAU_RS06155	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MESAU_RS06160	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MESAU_RS06165	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MESAU_RS06175	COG0668	transmembrane transport
MESAU_RS06180	COG0799	negative regulation of ribosome biogenesis
MESAU_RS06185	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MESAU_RS06195	COG0793	Belongs to the peptidase S41A family
MESAU_RS06205	COG0494	nUDIX hydrolase
MESAU_RS06210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MESAU_RS06215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MESAU_RS06225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MESAU_RS06260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MESAU_RS06265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MESAU_RS06305	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MESAU_RS06310	COG3750	Belongs to the UPF0335 family
MESAU_RS06325	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MESAU_RS06345	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MESAU_RS06350	COG1692	metallophosphoesterase
MESAU_RS06355	COG0861	Integral membrane protein TerC family
MESAU_RS06380	COG0217	transcriptional regulatory protein
MESAU_RS06400	COG0254	rRNA binding
MESAU_RS06405	COG1132	(ABC) transporter
MESAU_RS06410	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MESAU_RS06435	COG1272	protein, Hemolysin III
MESAU_RS06440	COG0483	inositol monophosphate 1-phosphatase activity
MESAU_RS06445	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MESAU_RS06465	COG1522	sequence-specific DNA binding
MESAU_RS06470	COG2226	methyltransferase
MESAU_RS06495	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MESAU_RS06500	COG2002	toxin-antitoxin pair type II binding
MESAU_RS06510	COG0632	four-way junction helicase activity
MESAU_RS06515	COG2255	four-way junction helicase activity
MESAU_RS06520	COG1408	metallophosphoesterase
MESAU_RS06530	COG0824	Thioesterase
MESAU_RS06540	COG0848	biopolymer transport protein
MESAU_RS06550	COG0823	Involved in the tonB-independent uptake of proteins
MESAU_RS06560	COG2885	chlorophyll binding
MESAU_RS06570	COG0037	tRNA processing
MESAU_RS06575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MESAU_RS06590	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MESAU_RS06605	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MESAU_RS06610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MESAU_RS06635	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MESAU_RS06655	COG0488	(ABC) transporter
MESAU_RS06675	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
MESAU_RS06690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MESAU_RS06695	COG0765	amino acid transport
MESAU_RS06700	COG1126	abc transporter atp-binding protein
MESAU_RS06705	COG1329	Transcriptional regulator
MESAU_RS06710	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MESAU_RS06725	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS06730	COG0183	Belongs to the thiolase family
MESAU_RS06735	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
MESAU_RS06740	COG0372	Belongs to the citrate synthase family
MESAU_RS06780	COG0583	DNA-binding transcription factor activity
MESAU_RS06785	COG2223	nitrite transmembrane transporter activity
MESAU_RS06805	COG0469	pyruvate kinase activity
MESAU_RS06820	COG0457	Tetratricopeptide repeat
MESAU_RS06825	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MESAU_RS06830	COG3755	Protein conserved in bacteria
MESAU_RS06835	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MESAU_RS06850	COG1595	DNA-templated transcription, initiation
MESAU_RS06855	COG1921	L-seryl-tRNASec selenium transferase activity
MESAU_RS06865	COG1126	abc transporter atp-binding protein
MESAU_RS06870	COG0765	amino acid transport
MESAU_RS06875	COG0765	amino acid transport
MESAU_RS06900	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MESAU_RS06905	COG0741	lytic transglycosylase activity
MESAU_RS06905	COG1196	nuclear chromosome segregation
MESAU_RS06905	COG0739	heme binding
MESAU_RS06915	COG5002	protein histidine kinase activity
MESAU_RS06915	COG2205	protein histidine kinase activity
MESAU_RS06915	COG0784	Response regulator, receiver
MESAU_RS06920	COG0142	geranyltranstransferase activity
MESAU_RS06925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MESAU_RS06930	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MESAU_RS06980	COG0640	Transcriptional regulator
MESAU_RS06995	COG0604	alcohol dehydrogenase
MESAU_RS07025	COG0346	lactoylglutathione lyase activity
MESAU_RS07045	COG3588	fructose-bisphosphate aldolase
MESAU_RS07050	COG0126	phosphoglycerate kinase activity
MESAU_RS07080	COG0450	alkyl hydroperoxide reductase
MESAU_RS07085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MESAU_RS07085	COG3453	Protein conserved in bacteria
MESAU_RS07090	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MESAU_RS07095	COG0564	pseudouridine synthase activity
MESAU_RS07105	COG0346	lactoylglutathione lyase activity
MESAU_RS07130	COG0784	Response regulator, receiver
MESAU_RS07130	COG5002	protein histidine kinase activity
MESAU_RS07130	COG2205	protein histidine kinase activity
MESAU_RS07135	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MESAU_RS07140	COG0573	inorganic phosphate transmembrane transporter activity
MESAU_RS07145	COG0581	inorganic phosphate transmembrane transporter activity
MESAU_RS07150	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MESAU_RS07155	COG0704	Plays a role in the regulation of phosphate uptake
MESAU_RS07160	COG0745	RESPONSE REGULATOR receiver
MESAU_RS07165	COG1940	carbohydrate kinase activity
MESAU_RS07170	COG4213	ABC transporter substrate-binding protein
MESAU_RS07175	COG4214	carbohydrate transport
MESAU_RS07210	COG0784	Response regulator, receiver
MESAU_RS07230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MESAU_RS07245	COG3920	Histidine kinase
MESAU_RS07270	COG0346	lactoylglutathione lyase activity
MESAU_RS07275	COG0400	carboxylic ester hydrolase activity
MESAU_RS07295	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MESAU_RS07320	COG1231	oxidoreductase activity
MESAU_RS07325	COG3842	ATPase activity
MESAU_RS07335	COG1176	ABC-type spermidine putrescine transport system, permease component I
MESAU_RS07355	COG2199	diguanylate cyclase activity
MESAU_RS07355	COG2200	EAL domain
MESAU_RS07355	COG2203	Gaf domain
MESAU_RS07360	COG0745	RESPONSE REGULATOR receiver
MESAU_RS07365	COG0745	RESPONSE REGULATOR receiver
MESAU_RS07375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MESAU_RS07415	COG1653	transport
MESAU_RS07420	COG1846	Transcriptional regulator
MESAU_RS07420	COG1940	carbohydrate kinase activity
MESAU_RS07425	COG0306	phosphate transporter
MESAU_RS07440	COG4689	acetoacetate decarboxylase
MESAU_RS07445	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS07450	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MESAU_RS07470	COG0318	PFAM AMP-dependent synthetase and ligase
MESAU_RS07485	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MESAU_RS07490	COG0508	dehydrogenase complex catalyzes the overall conversion of
MESAU_RS07490	COG0022	dehydrogenase e1 component
MESAU_RS07495	COG0508	dehydrogenase complex catalyzes the overall conversion of
MESAU_RS07505	COG2390	Transcriptional regulator
MESAU_RS07510	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MESAU_RS07520	COG3842	ATPase activity
MESAU_RS07525	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MESAU_RS07540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MESAU_RS07560	COG3732	PTS system glucitol sorbitol-specific
MESAU_RS07580	COG2390	Transcriptional regulator
MESAU_RS07590	COG1070	Carbohydrate kinase
MESAU_RS07615	COG1172	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS07625	COG1082	Xylose isomerase domain protein TIM barrel
MESAU_RS07640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MESAU_RS07645	COG0702	epimerase
MESAU_RS07650	COG0583	DNA-binding transcription factor activity
MESAU_RS07660	COG1473	amidohydrolase
MESAU_RS07670	COG0523	cobalamin synthesis protein
MESAU_RS07675	COG0425	Belongs to the sulfur carrier protein TusA family
MESAU_RS07685	COG0825	malonyl-CoA metabolic process
MESAU_RS07690	COG4974	Belongs to the 'phage' integrase family
MESAU_RS07700	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MESAU_RS07705	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MESAU_RS07710	COG4536	flavin adenine dinucleotide binding
MESAU_RS07720	COG2719	SpoVR family
MESAU_RS07725	COG2718	Belongs to the UPF0229 family
MESAU_RS07730	COG2766	serine protein kinase
MESAU_RS07735	COG0028	Belongs to the TPP enzyme family
MESAU_RS07770	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MESAU_RS07775	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MESAU_RS07800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MESAU_RS07805	COG2226	methyltransferase
MESAU_RS07810	COG4178	(ABC) transporter
MESAU_RS07815	COG1215	transferase activity, transferring glycosyl groups
MESAU_RS07820	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MESAU_RS07820	COG2813	Specifically methylates the guanine in position
MESAU_RS07825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MESAU_RS07830	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MESAU_RS07835	COG0287	Prephenate dehydrogenase
MESAU_RS07855	COG0667	Aldo Keto reductase
MESAU_RS07895	COG2884	Cell division ATP-binding protein ftsE
MESAU_RS07905	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MESAU_RS07905	COG0037	tRNA processing
MESAU_RS07920	COG0583	DNA-binding transcription factor activity
MESAU_RS07935	COG0640	Transcriptional regulator
MESAU_RS07950	COG0165	Argininosuccinate lyase
MESAU_RS07955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MESAU_RS07960	COG3300	MHYT domain
MESAU_RS07960	COG5001	Diguanylate cyclase
MESAU_RS07975	COG1175	transmembrane transport
MESAU_RS07980	COG0395	ABC-type sugar transport system, permease component
MESAU_RS07985	COG3842	ATPase activity
MESAU_RS07990	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MESAU_RS07995	COG3842	ATPase activity
MESAU_RS08030	COG5001	Diguanylate cyclase
MESAU_RS08030	COG5002	protein histidine kinase activity
MESAU_RS08030	COG3447	MASE1 domain protein
MESAU_RS08035	COG1250	3-hydroxyacyl-CoA dehydrogenase
MESAU_RS08040	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MESAU_RS08045	COG2086	electron transfer activity
MESAU_RS08065	COG0300	oxidoreductase activity
MESAU_RS08075	COG0697	spore germination
MESAU_RS08080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MESAU_RS08150	COG0653	protein targeting
MESAU_RS08155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MESAU_RS08165	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MESAU_RS08170	COG0456	acetyltransferase
MESAU_RS08170	COG0454	-acetyltransferase
MESAU_RS08175	COG0494	nUDIX hydrolase
MESAU_RS08195	COG1040	competence protein
MESAU_RS08215	COG1846	Transcriptional regulator
MESAU_RS08225	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MESAU_RS08230	COG4191	Histidine kinase
MESAU_RS08230	COG0784	Response regulator, receiver
MESAU_RS08235	COG0527	aspartate kinase activity
MESAU_RS08245	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MESAU_RS08250	COG2890	protein-(glutamine-N5) methyltransferase activity
MESAU_RS08260	COG0542	response to heat
MESAU_RS08270	COG1376	ErfK ybiS ycfS ynhG family protein
MESAU_RS08275	COG3548	integral membrane protein
MESAU_RS08280	COG0477	Major facilitator Superfamily
MESAU_RS08285	COG0739	heme binding
MESAU_RS08320	COG3609	addiction module antidote protein, CC2985 family
MESAU_RS08365	COG2910	NAD(P)H-binding
MESAU_RS08385	COG1879	ABC-type sugar transport system periplasmic component
MESAU_RS08395	COG1129	ABC transporter
MESAU_RS08410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MESAU_RS08415	COG0601	transmembrane transport
MESAU_RS08420	COG0747	negative chemotaxis
MESAU_RS08440	COG5564	TIM-barrel signal transduction protein
MESAU_RS08445	COG5441	Belongs to the UPF0261 family
MESAU_RS08455	COG2182	Extracellular solute-binding protein
MESAU_RS08460	COG1175	transmembrane transport
MESAU_RS08475	COG3842	ATPase activity
MESAU_RS08480	COG3842	ATPase activity
MESAU_RS08505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MESAU_RS08515	COG4948	Mandelate Racemase Muconate Lactonizing
MESAU_RS08530	COG0673	inositol 2-dehydrogenase activity
MESAU_RS08535	COG1082	Xylose isomerase domain protein TIM barrel
MESAU_RS08540	COG3639	organic phosphonate transmembrane transporter activity
MESAU_RS08555	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MESAU_RS08575	COG4778	phosphonate C-P lyase system protein PhnL
MESAU_RS08580	COG4107	phosphonate C-P lyase system protein PhnK
MESAU_RS08585	COG3627	carbon phosphorus lyase activity
MESAU_RS08590	COG3626	phosphonate metabolism
MESAU_RS08595	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
MESAU_RS08600	COG3624	Phosphonate C-P lyase system protein PhnG
MESAU_RS08605	COG2188	Transcriptional regulator
MESAU_RS08610	COG1063	alcohol dehydrogenase
MESAU_RS08615	COG1172	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS08625	COG1879	ABC-type sugar transport system periplasmic component
MESAU_RS08635	COG2721	sulfolactate sulfo-lyase activity
MESAU_RS08640	COG1802	Transcriptional regulator
MESAU_RS08650	COG2847	Copper chaperone PCu(A)C
MESAU_RS08665	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MESAU_RS08670	COG0583	DNA-binding transcription factor activity
MESAU_RS08690	COG1175	transmembrane transport
MESAU_RS08695	COG0395	ABC-type sugar transport system, permease component
MESAU_RS08700	COG3842	ATPase activity
MESAU_RS08715	COG0667	Aldo Keto reductase
MESAU_RS08720	COG0735	belongs to the Fur family
MESAU_RS08725	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MESAU_RS08725	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MESAU_RS08730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MESAU_RS08765	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS08770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MESAU_RS08770	COG4651	solute:proton antiporter activity
MESAU_RS08780	COG1648	precorrin-2 dehydrogenase activity
MESAU_RS08780	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MESAU_RS08790	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MESAU_RS08795	COG0175	sulfate reduction
MESAU_RS08805	COG0693	protein deglycase activity
MESAU_RS08810	COG3239	Fatty acid desaturase
MESAU_RS08820	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MESAU_RS08825	COG2860	membrane
MESAU_RS08840	COG0604	alcohol dehydrogenase
MESAU_RS08845	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MESAU_RS08850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MESAU_RS08855	COG0116	Belongs to the methyltransferase superfamily
MESAU_RS08855	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MESAU_RS08870	COG2423	ornithine cyclodeaminase activity
MESAU_RS08880	COG0776	regulation of translation
MESAU_RS08885	COG0616	signal peptide processing
MESAU_RS08895	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
MESAU_RS08900	COG1137	ATPase activity
MESAU_RS08905	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MESAU_RS08910	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MESAU_RS08915	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MESAU_RS08935	COG1280	lysine exporter protein (LysE YggA)
MESAU_RS08940	COG0154	amidase activity
MESAU_RS08945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MESAU_RS09015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MESAU_RS09040	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MESAU_RS09045	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MESAU_RS09050	COG2226	methyltransferase
MESAU_RS09055	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MESAU_RS09060	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MESAU_RS09070	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MESAU_RS09075	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MESAU_RS09085	COG1079	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS09090	COG1079	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS09095	COG3845	ABC transporter
MESAU_RS09100	COG2900	Belongs to the SlyX family
MESAU_RS09115	COG1744	ABC transporter substrate-binding protein PnrA-like
MESAU_RS09160	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MESAU_RS09170	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MESAU_RS09175	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MESAU_RS09180	COG2205	protein histidine kinase activity
MESAU_RS09185	COG0745	RESPONSE REGULATOR receiver
MESAU_RS09190	COG2814	Major facilitator Superfamily
MESAU_RS09210	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MESAU_RS09230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MESAU_RS09245	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MESAU_RS09245	COG0446	pyridine nucleotide-disulphide oxidoreductase
MESAU_RS09265	COG0673	inositol 2-dehydrogenase activity
MESAU_RS09300	COG1960	acyl-CoA dehydrogenase activity
MESAU_RS09315	COG0463	Glycosyl transferase, family 2
MESAU_RS09330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MESAU_RS09335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MESAU_RS09350	COG0531	amino acid
MESAU_RS09395	COG3842	ATPase activity
MESAU_RS09415	COG2814	Major facilitator Superfamily
MESAU_RS09430	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS09440	COG3842	ATPase activity
MESAU_RS09445	COG0395	ABC-type sugar transport system, permease component
MESAU_RS09450	COG1175	transmembrane transport
MESAU_RS09455	COG1653	transport
MESAU_RS09460	COG1012	belongs to the aldehyde dehydrogenase family
MESAU_RS09465	COG1024	Enoyl-CoA hydratase
MESAU_RS09480	COG1609	Transcriptional regulator
MESAU_RS09515	COG0071	Belongs to the small heat shock protein (HSP20) family
MESAU_RS09525	COG0070	glutamate synthase
MESAU_RS09525	COG0067	glutamate synthase
MESAU_RS09525	COG0069	glutamate synthase activity
MESAU_RS09540	COG2951	lytic endotransglycosylase activity
MESAU_RS09545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MESAU_RS09565	COG0330	HflC and HflK could
MESAU_RS09570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MESAU_RS09570	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MESAU_RS09575	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MESAU_RS09580	COG0737	Belongs to the 5'-nucleotidase family
MESAU_RS09590	COG5310	Homospermidine synthase
MESAU_RS09610	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MESAU_RS09610	COG3743	rRNA binding
MESAU_RS09620	COG2204	response regulator
MESAU_RS09625	COG3108	Peptidase M15
MESAU_RS09635	COG0800	Aldolase
MESAU_RS09640	COG1054	Belongs to the UPF0176 family
MESAU_RS09650	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS09655	COG3795	YCII-related domain
MESAU_RS09665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MESAU_RS09670	COG0765	amino acid transport
MESAU_RS09700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MESAU_RS09715	COG0583	DNA-binding transcription factor activity
MESAU_RS09720	COG0154	amidase activity
MESAU_RS09785	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MESAU_RS09800	COG2814	Major facilitator Superfamily
MESAU_RS09810	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
MESAU_RS09815	COG5443	negative regulation of bacterial-type flagellum assembly
MESAU_RS09835	COG1749	Flagellar hook protein flgE
MESAU_RS09875	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MESAU_RS09880	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MESAU_RS09885	COG1338	Plays a role in the flagellum-specific transport system
MESAU_RS09895	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
MESAU_RS09905	COG1706	bacterial-type flagellum-dependent cell motility
MESAU_RS09910	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
MESAU_RS09915	COG4786	Flagellar basal body rod
MESAU_RS09920	COG1677	Flagellar hook-basal body complex protein FliE
MESAU_RS09925	COG1558	bacterial-type flagellum-dependent cell motility
MESAU_RS09930	COG1815	bacterial-type flagellum-dependent cell motility
MESAU_RS09940	COG1157	protein secretion by the type III secretion system
MESAU_RS09945	COG4786	Flagellar basal body rod
MESAU_RS09955	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MESAU_RS09960	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MESAU_RS09965	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MESAU_RS09970	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MESAU_RS09975	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MESAU_RS09990	COG2771	luxR family
MESAU_RS10005	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MESAU_RS10010	COG3842	ATPase activity
MESAU_RS10015	COG1176	ABC-type spermidine putrescine transport system, permease component I
MESAU_RS10020	COG1177	transmembrane transport
MESAU_RS10040	COG2183	response to ionizing radiation
MESAU_RS10045	COG0583	DNA-binding transcription factor activity
MESAU_RS10050	COG1960	acyl-CoA dehydrogenase activity
MESAU_RS10065	COG1305	Transglutaminase-like
MESAU_RS10090	COG3795	YCII-related domain
MESAU_RS10095	COG4941	Belongs to the sigma-70 factor family
MESAU_RS10100	COG1012	belongs to the aldehyde dehydrogenase family
MESAU_RS10105	COG2358	TRAP transporter, solute receptor (TAXI family
MESAU_RS10120	COG0243	molybdopterin cofactor binding
MESAU_RS10130	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MESAU_RS10135	COG1116	anion transmembrane transporter activity
MESAU_RS10140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MESAU_RS10145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MESAU_RS10150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MESAU_RS10170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MESAU_RS10220	COG2188	Transcriptional regulator
MESAU_RS10225	COG2945	thiolester hydrolase activity
MESAU_RS10225	COG0596	Alpha beta hydrolase
MESAU_RS10245	COG0235	Class ii aldolase
MESAU_RS10250	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MESAU_RS10255	COG1250	3-hydroxyacyl-CoA dehydrogenase
MESAU_RS10260	COG1116	anion transmembrane transporter activity
MESAU_RS10265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MESAU_RS10285	COG1129	ABC transporter
MESAU_RS10295	COG1079	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS10300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MESAU_RS10305	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MESAU_RS10310	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS10315	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MESAU_RS10325	COG0673	inositol 2-dehydrogenase activity
MESAU_RS10330	COG0482	sulfurtransferase activity
MESAU_RS10355	COG0745	RESPONSE REGULATOR receiver
MESAU_RS10400	COG0435	Glutathione S-transferase
MESAU_RS10420	COG0508	dehydrogenase complex catalyzes the overall conversion of
MESAU_RS10420	COG0596	Alpha beta hydrolase
MESAU_RS10430	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MESAU_RS10445	COG0477	Major facilitator Superfamily
MESAU_RS10455	COG3180	Ammonia monooxygenase
MESAU_RS10465	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS10480	COG4456	Virulence-associated protein
MESAU_RS10490	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MESAU_RS10495	COG0512	Glutamine amidotransferase of anthranilate synthase
MESAU_RS10495	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MESAU_RS10505	COG2814	Major facilitator Superfamily
MESAU_RS10510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MESAU_RS10555	COG1335	isochorismatase
MESAU_RS10560	COG2759	Belongs to the formate--tetrahydrofolate ligase family
MESAU_RS10600	COG1435	thymidine kinase activity
MESAU_RS10610	COG4176	ABC-type proline glycine betaine transport system permease component
MESAU_RS10625	COG0745	RESPONSE REGULATOR receiver
MESAU_RS10645	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MESAU_RS10665	COG0714	Associated with various cellular activities
MESAU_RS10675	COG0494	nUDIX hydrolase
MESAU_RS10695	COG0408	coproporphyrinogen oxidase activity
MESAU_RS10705	COG0789	Transcriptional regulator
MESAU_RS10710	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MESAU_RS10720	COG1132	(ABC) transporter
MESAU_RS10725	COG1132	(ABC) transporter
MESAU_RS10755	COG2857	Cytochrome c1
MESAU_RS10755	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MESAU_RS10765	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MESAU_RS10780	COG2233	PERMEase
MESAU_RS10785	COG0402	S-adenosylhomocysteine deaminase activity
MESAU_RS10800	COG0012	GTP binding
MESAU_RS10805	COG0193	aminoacyl-tRNA hydrolase activity
MESAU_RS10810	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MESAU_RS10815	COG1846	Transcriptional regulator
MESAU_RS10825	COG2223	nitrite transmembrane transporter activity
MESAU_RS10830	COG2207	Transcriptional regulator
MESAU_RS10835	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MESAU_RS10860	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MESAU_RS10880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MESAU_RS10890	COG2205	protein histidine kinase activity
MESAU_RS10895	COG0745	RESPONSE REGULATOR receiver
MESAU_RS10900	COG1846	Transcriptional regulator
MESAU_RS10905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MESAU_RS10915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MESAU_RS10925	COG1278	Cold shock
MESAU_RS10930	COG1278	Cold shock
MESAU_RS10960	COG0457	Tetratricopeptide repeat
MESAU_RS10965	COG5507	3-demethylubiquinone-9 3-methyltransferase
MESAU_RS10995	COG0488	(ABC) transporter
MESAU_RS11005	COG0556	nucleotide-excision repair
MESAU_RS11040	COG0277	FAD linked oxidase domain protein
MESAU_RS11060	COG1597	lipid kinase activity
MESAU_RS11070	COG4948	Mandelate Racemase Muconate Lactonizing
MESAU_RS11080	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MESAU_RS11085	COG1607	acyl-coa hydrolase
MESAU_RS11115	COG2273	Hydrolase Family 16
MESAU_RS11115	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
MESAU_RS11130	COG1253	flavin adenine dinucleotide binding
MESAU_RS11140	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
MESAU_RS11165	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MESAU_RS11170	COG0859	PFAM glycosyl transferase family 9
MESAU_RS11180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MESAU_RS11200	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MESAU_RS11200	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MESAU_RS11205	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MESAU_RS11210	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MESAU_RS11215	COG0463	Glycosyl transferase, family 2
MESAU_RS11220	COG1522	sequence-specific DNA binding
MESAU_RS11225	COG0492	ferredoxin-NADP+ reductase activity
MESAU_RS11230	COG0583	DNA-binding transcription factor activity
MESAU_RS11240	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MESAU_RS11255	COG0436	Aminotransferase
MESAU_RS11265	COG2199	diguanylate cyclase activity
MESAU_RS11265	COG2200	EAL domain
MESAU_RS11265	COG2203	Gaf domain
MESAU_RS11270	COG0625	glutathione transferase activity
MESAU_RS11275	COG1278	Cold shock
MESAU_RS11285	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MESAU_RS11300	COG1653	transport
MESAU_RS11325	COG1295	ribonuclease BN
MESAU_RS11355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MESAU_RS11370	COG2814	Major facilitator Superfamily
MESAU_RS11380	COG4221	oxidoreductase activity
MESAU_RS11390	COG0583	DNA-binding transcription factor activity
MESAU_RS11400	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MESAU_RS11405	COG1914	H( )-stimulated, divalent metal cation uptake system
MESAU_RS11410	COG1321	iron dependent repressor
MESAU_RS11430	COG2321	neutral zinc metallopeptidase
MESAU_RS11440	COG0505	Belongs to the CarA family
MESAU_RS11455	COG0596	Alpha beta hydrolase
MESAU_RS11480	COG2814	Major facilitator Superfamily
MESAU_RS11505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MESAU_RS11530	COG1695	Transcriptional regulator
MESAU_RS11550	COG5001	Diguanylate cyclase
MESAU_RS11550	COG3300	MHYT domain
MESAU_RS11555	COG2223	nitrite transmembrane transporter activity
MESAU_RS11560	COG1522	sequence-specific DNA binding
MESAU_RS11575	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MESAU_RS11580	COG0583	DNA-binding transcription factor activity
MESAU_RS11610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MESAU_RS11615	COG1309	transcriptional regulator
MESAU_RS11625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MESAU_RS11630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MESAU_RS11635	COG2197	response regulator
MESAU_RS11645	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS11655	COG2983	Belongs to the UPF0260 family
MESAU_RS11665	COG2968	Membrane
MESAU_RS11700	COG0582	viral genome integration into host DNA
MESAU_RS11710	COG2207	Transcriptional regulator
MESAU_RS11740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MESAU_RS11740	COG2207	Transcriptional regulator
MESAU_RS11745	COG1486	melibiose metabolic process
MESAU_RS11750	COG0747	negative chemotaxis
MESAU_RS11760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MESAU_RS11765	COG4172	Belongs to the ABC transporter superfamily
MESAU_RS11770	COG1486	melibiose metabolic process
MESAU_RS11775	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MESAU_RS11780	COG0424	maF-like protein
MESAU_RS11785	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MESAU_RS11795	COG5328	Belongs to the UPF0262 family
MESAU_RS11800	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MESAU_RS11810	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MESAU_RS11840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MESAU_RS11845	COG4177	L-phenylalanine transmembrane transporter activity
MESAU_RS11875	COG2132	Multicopper oxidase
MESAU_RS11890	COG3775	system Galactitol-specific IIC component
MESAU_RS11930	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
MESAU_RS11950	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MESAU_RS11960	COG2304	oxidoreductase activity
MESAU_RS11965	COG0129	dihydroxy-acid dehydratase activity
MESAU_RS11970	COG0363	glucosamine-6-phosphate deaminase activity
MESAU_RS11975	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MESAU_RS11990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MESAU_RS12000	COG0174	glutamine synthetase
MESAU_RS12020	COG2224	Isocitrate lyase
MESAU_RS12045	COG3842	ATPase activity
MESAU_RS12050	COG1176	ABC-type spermidine putrescine transport system, permease component I
MESAU_RS12055	COG1177	transmembrane transport
MESAU_RS12065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MESAU_RS12070	COG2205	protein histidine kinase activity
MESAU_RS12075	COG5490	Phasin protein
MESAU_RS12095	COG0583	DNA-binding transcription factor activity
MESAU_RS12100	COG3845	ABC transporter
MESAU_RS12105	COG1079	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS12110	COG4603	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS12130	COG0583	DNA-binding transcription factor activity
MESAU_RS12135	COG2233	PERMEase
MESAU_RS12150	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MESAU_RS12155	COG0523	cobalamin synthesis protein
MESAU_RS12170	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MESAU_RS12175	COG0163	prenyltransferase activity
MESAU_RS12185	COG1175	transmembrane transport
MESAU_RS12200	COG1175	transmembrane transport
MESAU_RS12205	COG0395	ABC-type sugar transport system, permease component
MESAU_RS12220	COG2188	Transcriptional regulator
MESAU_RS12225	COG4821	SIS domain
MESAU_RS12245	COG0156	8-amino-7-oxononanoate synthase activity
MESAU_RS12275	COG4566	intracellular signal transduction
MESAU_RS12280	COG4191	Histidine kinase
MESAU_RS12320	COG2010	Cytochrome c
MESAU_RS12350	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MESAU_RS12370	COG3794	PFAM blue (type 1) copper domain protein
MESAU_RS12375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MESAU_RS12390	COG1012	belongs to the aldehyde dehydrogenase family
MESAU_RS12405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MESAU_RS12410	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
MESAU_RS12420	COG0438	transferase activity, transferring glycosyl groups
MESAU_RS12430	COG0367	asparagine synthase
MESAU_RS12465	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MESAU_RS12470	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MESAU_RS12475	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MESAU_RS12480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MESAU_RS12490	COG1596	polysaccharide export
MESAU_RS12495	COG2890	protein-(glutamine-N5) methyltransferase activity
MESAU_RS12505	COG0318	PFAM AMP-dependent synthetase and ligase
MESAU_RS12510	COG0367	asparagine synthase
MESAU_RS12515	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MESAU_RS12520	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MESAU_RS12520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MESAU_RS12530	COG4191	Histidine kinase
MESAU_RS12530	COG0784	Response regulator, receiver
MESAU_RS12550	COG0492	ferredoxin-NADP+ reductase activity
MESAU_RS12550	COG3118	belongs to the thioredoxin family
MESAU_RS12595	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MESAU_RS12600	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MESAU_RS12610	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MESAU_RS12620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MESAU_RS12630	COG3685	Protein conserved in bacteria
MESAU_RS12650	COG3546	catalase activity
MESAU_RS12655	COG4187	Peptidase family M20/M25/M40
MESAU_RS12745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MESAU_RS12760	COG2072	flavoprotein involved in K transport
MESAU_RS12765	COG0251	oxidation-reduction process
MESAU_RS12775	COG1012	belongs to the aldehyde dehydrogenase family
MESAU_RS12780	COG0583	DNA-binding transcription factor activity
MESAU_RS12795	COG0477	Major facilitator Superfamily
MESAU_RS12800	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MESAU_RS12805	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MESAU_RS12810	COG1845	cytochrome c oxidase, subunit III
MESAU_RS12815	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MESAU_RS12865	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS12870	COG1312	Catalyzes the dehydration of D-mannonate
MESAU_RS12875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MESAU_RS12885	COG0174	glutamine synthetase
MESAU_RS12895	COG0837	glucose binding
MESAU_RS12895	COG1737	Transcriptional regulator
MESAU_RS12925	COG1570	exodeoxyribonuclease VII activity
MESAU_RS12930	COG0583	DNA-binding transcription factor activity
MESAU_RS12985	COG0277	FAD linked oxidase domain protein
MESAU_RS12990	COG0277	FAD linked oxidase domain protein
MESAU_RS12995	COG0247	lactate metabolic process
MESAU_RS13000	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MESAU_RS13005	COG1376	ErfK ybiS ycfS ynhG family protein
MESAU_RS13010	COG2818	Glycosylase
MESAU_RS13020	COG0124	histidyl-tRNA synthetase
MESAU_RS13025	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MESAU_RS13030	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MESAU_RS13035	COG0318	PFAM AMP-dependent synthetase and ligase
MESAU_RS13045	COG2226	methyltransferase
MESAU_RS13070	COG0765	amino acid transport
MESAU_RS13080	COG0583	DNA-binding transcription factor activity
MESAU_RS13085	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
MESAU_RS13090	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MESAU_RS13095	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MESAU_RS13095	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MESAU_RS13100	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
MESAU_RS13115	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MESAU_RS13115	COG0519	Catalyzes the synthesis of GMP from XMP
MESAU_RS13135	COG3328	transposase activity
MESAU_RS13165	COG3916	Acyl-homoserine-lactone synthase
MESAU_RS13195	COG0517	IMP dehydrogenase activity
MESAU_RS13205	COG0517	IMP dehydrogenase activity
MESAU_RS13225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MESAU_RS13230	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MESAU_RS13235	COG0438	transferase activity, transferring glycosyl groups
MESAU_RS13240	COG2226	methyltransferase
MESAU_RS13245	COG0438	transferase activity, transferring glycosyl groups
MESAU_RS13245	COG1216	Glycosyl transferase, family 2
MESAU_RS13255	COG1132	(ABC) transporter
MESAU_RS13260	COG1216	Glycosyl transferase, family 2
MESAU_RS13265	COG0535	radical SAM domain protein
MESAU_RS13275	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
MESAU_RS13280	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MESAU_RS13300	COG1131	(ABC) transporter
MESAU_RS13305	COG0842	Transport permease protein
MESAU_RS13320	COG0765	amino acid transport
MESAU_RS13325	COG1126	abc transporter atp-binding protein
MESAU_RS13335	COG0726	polysaccharide deacetylase
MESAU_RS13350	COG0165	Argininosuccinate lyase
MESAU_RS13355	COG0583	DNA-binding transcription factor activity
MESAU_RS13360	COG0110	maltose O-acetyltransferase activity
MESAU_RS13440	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MESAU_RS13445	COG5265	(ABC) transporter
MESAU_RS13490	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MESAU_RS13515	COG1172	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS13520	COG1172	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS13525	COG1129	ABC transporter
MESAU_RS13530	COG1879	ABC-type sugar transport system periplasmic component
MESAU_RS13545	COG4948	Mandelate Racemase Muconate Lactonizing
MESAU_RS13555	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS13610	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MESAU_RS13640	COG0010	Belongs to the arginase family
MESAU_RS13650	COG3246	L-lysine catabolic process to acetate
MESAU_RS13660	COG1175	transmembrane transport
MESAU_RS13670	COG2971	BadF BadG BcrA BcrD
MESAU_RS13690	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
MESAU_RS13710	COG0071	Belongs to the small heat shock protein (HSP20) family
MESAU_RS13715	COG0071	Belongs to the small heat shock protein (HSP20) family
MESAU_RS13720	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS13735	COG0395	ABC-type sugar transport system, permease component
MESAU_RS13740	COG1175	transmembrane transport
MESAU_RS13750	COG3842	ATPase activity
MESAU_RS13755	COG3307	-O-antigen
MESAU_RS13760	COG0367	asparagine synthase
MESAU_RS13765	COG2264	protein methyltransferase activity
MESAU_RS13780	COG2264	protein methyltransferase activity
MESAU_RS13785	COG1132	(ABC) transporter
MESAU_RS13820	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MESAU_RS13820	COG2755	lipolytic protein G-D-S-L family
MESAU_RS13825	COG1088	dTDP-glucose 4,6-dehydratase activity
MESAU_RS13830	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MESAU_RS13850	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS13905	COG3237	CsbD-like
MESAU_RS13945	COG1012	belongs to the aldehyde dehydrogenase family
MESAU_RS13950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MESAU_RS13955	COG2267	carboxylic ester hydrolase activity
MESAU_RS13960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MESAU_RS13965	COG0765	amino acid transport
MESAU_RS13970	COG1126	abc transporter atp-binding protein
MESAU_RS13975	COG4638	Rieske (2fe-2S)
MESAU_RS14010	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MESAU_RS14015	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MESAU_RS14020	COG4095	Psort location CytoplasmicMembrane, score
MESAU_RS14065	COG0649	NAD binding
MESAU_RS14075	COG1295	ribonuclease BN
MESAU_RS14090	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MESAU_RS14125	COG1175	transmembrane transport
MESAU_RS14135	COG0673	inositol 2-dehydrogenase activity
MESAU_RS14140	COG1082	Xylose isomerase domain protein TIM barrel
MESAU_RS14150	COG5001	Diguanylate cyclase
MESAU_RS14150	COG3300	MHYT domain
MESAU_RS14165	COG1609	Transcriptional regulator
MESAU_RS14175	COG1653	transport
MESAU_RS14180	COG1175	transmembrane transport
MESAU_RS14185	COG0395	ABC-type sugar transport system, permease component
MESAU_RS14195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MESAU_RS14200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MESAU_RS14205	COG1012	belongs to the aldehyde dehydrogenase family
MESAU_RS14215	COG0242	peptide deformylase activity
MESAU_RS14220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MESAU_RS14225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MESAU_RS14240	COG0154	amidase activity
MESAU_RS14255	COG3454	Phosphonate metabolism
MESAU_RS14290	COG4221	oxidoreductase activity
MESAU_RS14305	COG1473	amidohydrolase
MESAU_RS14360	COG2423	ornithine cyclodeaminase activity
MESAU_RS14370	COG2226	methyltransferase
MESAU_RS14380	COG0475	glutathione-regulated potassium exporter activity
MESAU_RS14390	COG2814	Major facilitator Superfamily
MESAU_RS14395	COG0583	DNA-binding transcription factor activity
MESAU_RS14415	COG0346	lactoylglutathione lyase activity
MESAU_RS14445	COG0395	ABC-type sugar transport system, permease component
MESAU_RS14450	COG1175	transmembrane transport
MESAU_RS14460	COG1609	Transcriptional regulator
MESAU_RS14470	COG1956	GAF domain-containing protein
MESAU_RS14480	COG2207	Transcriptional regulator
MESAU_RS14485	COG2855	membrane
MESAU_RS14495	COG4191	Histidine kinase
MESAU_RS14515	COG0667	Aldo Keto reductase
MESAU_RS14520	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MESAU_RS14565	COG0406	alpha-ribazole phosphatase activity
MESAU_RS14590	COG0667	Aldo Keto reductase
MESAU_RS14595	COG0583	DNA-binding transcription factor activity
MESAU_RS14600	COG4251	negative regulation of phosphorylation
MESAU_RS14600	COG3706	GGDEF domain
MESAU_RS14600	COG2203	Gaf domain
MESAU_RS14600	COG5001	Diguanylate cyclase
MESAU_RS14650	COG1129	ABC transporter
MESAU_RS14655	COG1172	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS14710	COG3756	Protein conserved in bacteria
MESAU_RS14730	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MESAU_RS14730	COG2755	lipolytic protein G-D-S-L family
MESAU_RS14770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MESAU_RS14800	COG0489	protein tyrosine kinase activity
MESAU_RS14800	COG3206	protein involved in exopolysaccharide biosynthesis
MESAU_RS14820	COG0297	glycogen (starch) synthase activity
MESAU_RS14850	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MESAU_RS14895	COG0625	glutathione transferase activity
MESAU_RS14900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MESAU_RS14905	COG0583	DNA-binding transcription factor activity
MESAU_RS14910	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS14940	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MESAU_RS14980	COG0488	(ABC) transporter
MESAU_RS15005	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MESAU_RS15015	COG3842	ATPase activity
MESAU_RS15025	COG1177	transmembrane transport
MESAU_RS15030	COG4149	molybdate abc transporter
MESAU_RS15035	COG0326	Molecular chaperone. Has ATPase activity
MESAU_RS15045	COG4178	(ABC) transporter
MESAU_RS15055	COG0697	spore germination
MESAU_RS15070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MESAU_RS15075	COG0583	DNA-binding transcription factor activity
MESAU_RS15080	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS15105	COG1393	Belongs to the ArsC family
MESAU_RS15115	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS15130	COG0583	DNA-binding transcription factor activity
MESAU_RS15180	COG2259	Doxx family
MESAU_RS15210	COG0850	regulation of cytokinetic process
MESAU_RS15215	COG2894	cell division
MESAU_RS15220	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MESAU_RS15255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MESAU_RS15260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MESAU_RS15270	COG3920	Histidine kinase
MESAU_RS15275	COG5006	permease, DMT superfamily
MESAU_RS15295	COG0583	DNA-binding transcription factor activity
MESAU_RS15305	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MESAU_RS15310	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MESAU_RS15315	COG2080	2 iron, 2 sulfur cluster binding
MESAU_RS15320	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MESAU_RS15325	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MESAU_RS15330	COG2080	2 iron, 2 sulfur cluster binding
MESAU_RS15335	COG1309	transcriptional regulator
MESAU_RS15340	COG0583	DNA-binding transcription factor activity
MESAU_RS15345	COG2814	Major facilitator Superfamily
MESAU_RS15375	COG0656	L-ascorbic acid biosynthetic process
MESAU_RS15395	COG5425	PFAM Usg family protein
MESAU_RS15405	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MESAU_RS15410	COG0459	protein refolding
MESAU_RS15450	COG1172	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS15455	COG1129	ABC transporter
MESAU_RS15465	COG1082	Xylose isomerase domain protein TIM barrel
MESAU_RS15470	COG0246	Mannitol dehydrogenase
MESAU_RS15475	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS15485	COG0673	inositol 2-dehydrogenase activity
MESAU_RS15505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MESAU_RS15550	COG0596	Alpha beta hydrolase
MESAU_RS15565	COG2169	Transcriptional regulator
MESAU_RS15565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MESAU_RS15575	COG2169	Transcriptional regulator
MESAU_RS15575	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MESAU_RS15580	COG1733	regulation of RNA biosynthetic process
MESAU_RS15600	COG5002	protein histidine kinase activity
MESAU_RS15600	COG5001	Diguanylate cyclase
MESAU_RS15615	COG3038	cytochrome b561
MESAU_RS15620	COG3177	Filamentation induced by cAMP protein fic
MESAU_RS15630	COG0747	negative chemotaxis
MESAU_RS15645	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS15650	COG2827	Endonuclease containing a URI domain
MESAU_RS15660	COG3511	phospholipase C
MESAU_RS15680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MESAU_RS15705	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MESAU_RS15725	COG1181	Belongs to the D-alanine--D-alanine ligase family
MESAU_RS15730	COG0628	permease
MESAU_RS15745	COG4191	Histidine kinase
MESAU_RS15785	COG0596	Alpha beta hydrolase
MESAU_RS15850	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MESAU_RS15855	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MESAU_RS15870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MESAU_RS15875	COG1116	anion transmembrane transporter activity
MESAU_RS15935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MESAU_RS15940	COG1609	Transcriptional regulator
MESAU_RS15950	COG0395	ABC-type sugar transport system, permease component
MESAU_RS15955	COG1175	transmembrane transport
MESAU_RS15985	COG1172	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS16010	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MESAU_RS16015	COG2986	histidine ammonia-lyase
MESAU_RS16025	COG2814	Major facilitator Superfamily
MESAU_RS16030	COG1172	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS16040	COG1172	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS16050	COG1129	ABC transporter
MESAU_RS16070	COG1175	transmembrane transport
MESAU_RS16095	COG0542	response to heat
MESAU_RS16105	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MESAU_RS16130	COG4214	carbohydrate transport
MESAU_RS16135	COG1129	ABC transporter
MESAU_RS16145	COG2186	Transcriptional regulator
MESAU_RS16155	COG1086	Polysaccharide biosynthesis protein
MESAU_RS16175	COG2271	Major facilitator Superfamily
MESAU_RS16180	COG1609	Transcriptional regulator
MESAU_RS16190	COG1129	ABC transporter
MESAU_RS16195	COG1172	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS16200	COG1172	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS16205	COG3265	gluconokinase activity
MESAU_RS16215	COG1959	2 iron, 2 sulfur cluster binding
MESAU_RS16220	COG4150	thiosulfate binding
MESAU_RS16235	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MESAU_RS16240	COG4208	sulfate ABC transporter
MESAU_RS16245	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MESAU_RS16250	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MESAU_RS16260	COG4953	penicillin-binding protein 1C
MESAU_RS16265	COG2373	Large extracellular alpha-helical protein
MESAU_RS16270	COG0729	surface antigen
MESAU_RS16285	COG0601	transmembrane transport
MESAU_RS16290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MESAU_RS16305	COG5598	trimethylamine methyltransferase
MESAU_RS16350	COG1959	2 iron, 2 sulfur cluster binding
MESAU_RS16355	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MESAU_RS16370	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS16380	COG1309	transcriptional regulator
MESAU_RS16390	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MESAU_RS16395	COG2852	Protein conserved in bacteria
MESAU_RS16430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MESAU_RS16435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MESAU_RS16440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MESAU_RS16450	COG0028	Belongs to the TPP enzyme family
MESAU_RS16455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MESAU_RS16470	COG3706	GGDEF domain
MESAU_RS16480	COG4106	trans-aconitate 2-methyltransferase activity
MESAU_RS16490	COG2020	methyltransferase activity
MESAU_RS16500	COG4221	oxidoreductase activity
MESAU_RS16510	COG1720	tRNA m6t6A37 methyltransferase activity
MESAU_RS16550	COG3093	addiction module antidote protein HigA
MESAU_RS16555	COG3549	Plasmid maintenance system killer
MESAU_RS16580	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MESAU_RS16585	COG3023	N-Acetylmuramoyl-L-alanine amidase
MESAU_RS16605	COG0626	cystathionine gamma-synthase activity
MESAU_RS16610	COG2001	Belongs to the MraZ family
MESAU_RS16615	COG0275	rRNA processing
MESAU_RS16630	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MESAU_RS16640	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MESAU_RS16645	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MESAU_RS16655	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MESAU_RS16660	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MESAU_RS16665	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MESAU_RS16670	COG1181	Belongs to the D-alanine--D-alanine ligase family
MESAU_RS16675	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MESAU_RS16680	COG0849	cell division
MESAU_RS16685	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MESAU_RS16695	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MESAU_RS16705	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MESAU_RS16730	COG0006	proline dipeptidase activity
MESAU_RS16735	COG2264	protein methyltransferase activity
MESAU_RS16740	COG1999	signal sequence binding
MESAU_RS16760	COG0300	oxidoreductase activity
MESAU_RS16780	COG2814	Major facilitator Superfamily
MESAU_RS16785	COG0534	Mate efflux family protein
MESAU_RS16800	COG5598	trimethylamine methyltransferase
MESAU_RS16810	COG0210	DNA helicase
MESAU_RS16830	COG0784	Response regulator, receiver
MESAU_RS16835	COG0784	Response regulator, receiver
MESAU_RS16835	COG4191	Histidine kinase
MESAU_RS16845	COG1522	sequence-specific DNA binding
MESAU_RS16860	COG0277	FAD linked oxidase domain protein
MESAU_RS16870	COG2837	iron assimilation
MESAU_RS16920	COG2814	Major facilitator Superfamily
MESAU_RS16940	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MESAU_RS16945	COG3585	molybdate ion transport
MESAU_RS16950	COG0725	ABC transporter, periplasmic molybdate-binding protein
MESAU_RS16955	COG4149	molybdate abc transporter
MESAU_RS16960	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MESAU_RS16965	COG2005	Transcriptional regulator
MESAU_RS16965	COG3585	molybdate ion transport
MESAU_RS16985	COG0330	HflC and HflK could
MESAU_RS16990	COG0330	HflC and HflK could
MESAU_RS17010	COG0560	Phosphoserine phosphatase
MESAU_RS17015	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MESAU_RS17020	COG2203	Gaf domain
MESAU_RS17020	COG2199	diguanylate cyclase activity
MESAU_RS17050	COG2175	clavaminate synthase activity
MESAU_RS17070	COG0028	Belongs to the TPP enzyme family
MESAU_RS17090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MESAU_RS17115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MESAU_RS17125	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MESAU_RS17130	COG3158	transport of potassium into the cell
MESAU_RS17135	COG3158	transport of potassium into the cell
MESAU_RS17150	COG1733	regulation of RNA biosynthetic process
MESAU_RS17155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MESAU_RS17175	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MESAU_RS17195	COG4691	Plasmid stability protein
MESAU_RS17200	COG1487	ribonuclease activity
MESAU_RS17210	COG1136	(ABC) transporter
MESAU_RS17210	COG0577	efflux transmembrane transporter activity
MESAU_RS17215	COG1136	(ABC) transporter
MESAU_RS17215	COG0577	efflux transmembrane transporter activity
MESAU_RS17220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MESAU_RS17225	COG0384	phenazine biosynthesis protein PhzF
MESAU_RS17235	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MESAU_RS17240	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
MESAU_RS17245	COG1797	cobyrinic acid a,c-diamide synthase activity
MESAU_RS17310	COG3214	Protein conserved in bacteria
MESAU_RS17320	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MESAU_RS17325	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MESAU_RS17330	COG0649	NAD binding
MESAU_RS17335	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
MESAU_RS17340	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MESAU_RS17345	COG3743	rRNA binding
MESAU_RS17345	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MESAU_RS17355	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MESAU_RS17360	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MESAU_RS17370	COG0713	ATP synthesis coupled electron transport
MESAU_RS17385	COG1007	ATP synthesis coupled electron transport
MESAU_RS17405	COG0346	lactoylglutathione lyase activity
MESAU_RS17415	COG0442	prolyl-tRNA aminoacylation
MESAU_RS17425	COG1136	(ABC) transporter
MESAU_RS17435	COG0321	lipoyl(octanoyl) transferase activity
MESAU_RS17445	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MESAU_RS17450	COG0045	succinate-CoA ligase (ADP-forming) activity
MESAU_RS17470	COG2239	Acts as a magnesium transporter
MESAU_RS17540	COG0251	oxidation-reduction process
MESAU_RS17555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MESAU_RS17560	COG0402	S-adenosylhomocysteine deaminase activity
MESAU_RS17570	COG2249	NAD(P)H dehydrogenase (quinone) activity
MESAU_RS17575	COG2249	NAD(P)H dehydrogenase (quinone) activity
MESAU_RS17590	COG2040	homocysteine
MESAU_RS17610	COG2814	Major facilitator Superfamily
MESAU_RS17620	COG0446	pyridine nucleotide-disulphide oxidoreductase
MESAU_RS17620	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MESAU_RS17630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MESAU_RS17635	COG3264	Mechanosensitive ion channel
MESAU_RS17635	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MESAU_RS17645	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MESAU_RS17660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MESAU_RS17695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MESAU_RS17715	COG0583	DNA-binding transcription factor activity
MESAU_RS17735	COG0646	methionine synthase
MESAU_RS17735	COG1410	methionine synthase
MESAU_RS17755	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MESAU_RS17780	COG5012	cobalamin binding
MESAU_RS17785	COG5598	trimethylamine methyltransferase
MESAU_RS17800	COG2081	HI0933 family
MESAU_RS17810	COG2304	oxidoreductase activity
MESAU_RS17820	COG0646	methionine synthase
MESAU_RS17820	COG1410	methionine synthase
MESAU_RS17840	COG0006	proline dipeptidase activity
MESAU_RS17870	COG0477	Major facilitator Superfamily
MESAU_RS17875	COG1505	serine-type exopeptidase activity
MESAU_RS17900	COG1960	acyl-CoA dehydrogenase activity
MESAU_RS17910	COG1492	cobalamin metabolic process
MESAU_RS17925	COG4172	Belongs to the ABC transporter superfamily
MESAU_RS17930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MESAU_RS17940	COG0747	negative chemotaxis
MESAU_RS17945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MESAU_RS17965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MESAU_RS17975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MESAU_RS18010	COG2017	converts alpha-aldose to the beta-anomer
MESAU_RS18015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MESAU_RS18025	COG1858	cytochrome C peroxidase
MESAU_RS18030	COG1522	sequence-specific DNA binding
MESAU_RS18065	COG3720	iron ion transport
MESAU_RS18070	COG4558	Periplasmic binding protein
MESAU_RS18075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MESAU_RS18080	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
MESAU_RS18085	COG1959	2 iron, 2 sulfur cluster binding
MESAU_RS18090	COG2733	membrane
MESAU_RS18105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MESAU_RS18110	COG0697	spore germination
MESAU_RS18125	COG2814	Major facilitator Superfamily
MESAU_RS18145	COG5002	protein histidine kinase activity
MESAU_RS18180	COG3142	Participates in the control of copper homeostasis
MESAU_RS18200	COG0071	Belongs to the small heat shock protein (HSP20) family
MESAU_RS18235	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MESAU_RS18250	COG0525	valine-tRNA ligase activity
MESAU_RS18260	COG0129	dihydroxy-acid dehydratase activity
MESAU_RS18275	COG0708	Exodeoxyribonuclease III
MESAU_RS18285	COG0316	Belongs to the HesB IscA family
MESAU_RS18290	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MESAU_RS18295	COG0018	arginyl-trna synthetase
MESAU_RS18310	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MESAU_RS18315	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MESAU_RS18320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MESAU_RS18325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MESAU_RS18330	COG0805	protein transport
MESAU_RS18335	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MESAU_RS18340	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MESAU_RS18345	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MESAU_RS18370	COG1862	Preprotein translocase
MESAU_RS18410	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MESAU_RS18430	COG0544	peptidyl-prolyl cis-trans isomerase activity
MESAU_RS18450	COG0024	Methionine aminopeptidase
MESAU_RS18500	COG3243	poly(R)-hydroxyalkanoic acid synthase
MESAU_RS18510	COG0436	Aminotransferase
MESAU_RS18525	COG1494	fructose-1,6-bisphosphatase
MESAU_RS18530	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MESAU_RS18535	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MESAU_RS18540	COG1752	Esterase of the alpha-beta hydrolase superfamily
MESAU_RS18545	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MESAU_RS18550	COG0302	gtp cyclohydrolase
MESAU_RS18565	COG0583	DNA-binding transcription factor activity
MESAU_RS18570	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MESAU_RS18580	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MESAU_RS18600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MESAU_RS18610	COG2030	dehydratase
MESAU_RS18620	COG1289	transmembrane transporter activity
MESAU_RS18625	COG0187	DNA topoisomerase II activity
MESAU_RS18635	COG4964	Belongs to the GSP D family
MESAU_RS18670	COG3706	GGDEF domain
MESAU_RS18675	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MESAU_RS18675	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MESAU_RS18680	COG0509	glycine decarboxylation via glycine cleavage system
MESAU_RS18685	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MESAU_RS18700	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MESAU_RS18715	COG1671	Belongs to the UPF0178 family
MESAU_RS18720	COG3791	Glutathione-dependent formaldehyde-activating
MESAU_RS18725	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MESAU_RS18730	COG4770	biotin carboxylase activity
MESAU_RS18755	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MESAU_RS18780	COG0784	Response regulator, receiver
MESAU_RS18790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MESAU_RS18795	COG2186	Transcriptional regulator
MESAU_RS18800	COG0626	cystathionine gamma-synthase activity
MESAU_RS18810	COG1175	transmembrane transport
MESAU_RS18815	COG0395	ABC-type sugar transport system, permease component
MESAU_RS18820	COG3842	ATPase activity
MESAU_RS18825	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MESAU_RS18850	COG0557	exoribonuclease II activity
MESAU_RS18855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MESAU_RS18865	COG0785	Cytochrome C biogenesis protein
MESAU_RS18875	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MESAU_RS18880	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MESAU_RS18890	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MESAU_RS18900	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MESAU_RS18905	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
MESAU_RS18910	COG3706	GGDEF domain
MESAU_RS18915	COG3791	Glutathione-dependent formaldehyde-activating
MESAU_RS18920	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MESAU_RS18955	COG5265	(ABC) transporter
MESAU_RS18965	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MESAU_RS18975	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MESAU_RS18980	COG0280	phosphate acetyltransferase
MESAU_RS18980	COG0281	malic enzyme
MESAU_RS19000	COG4948	Mandelate Racemase Muconate Lactonizing
MESAU_RS19010	COG1127	ABC transporter
MESAU_RS19040	COG0633	Ferredoxin
MESAU_RS19045	COG0492	ferredoxin-NADP+ reductase activity
MESAU_RS19050	COG0477	Major facilitator Superfamily
MESAU_RS19060	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MESAU_RS19070	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MESAU_RS19080	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MESAU_RS19080	COG0475	glutathione-regulated potassium exporter activity
MESAU_RS19105	COG3768	UPF0283 membrane protein
MESAU_RS19110	COG3106	COG3106 Predicted ATPase
MESAU_RS19135	COG0813	purine-nucleoside phosphorylase activity
MESAU_RS19205	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MESAU_RS19215	COG0740	serine-type endopeptidase activity
MESAU_RS19230	COG0629	single-stranded DNA binding
MESAU_RS19235	COG1765	OsmC-like protein
MESAU_RS19240	COG2095	MarC family integral membrane protein
MESAU_RS19255	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MESAU_RS19255	COG2169	Transcriptional regulator
MESAU_RS19260	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MESAU_RS19265	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MESAU_RS19285	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MESAU_RS19295	COG0343	queuine tRNA-ribosyltransferase activity
MESAU_RS19310	COG2308	Evidence 4 Homologs of previously reported genes of
MESAU_RS19345	COG3842	ATPase activity
MESAU_RS19360	COG0395	ABC-type sugar transport system, permease component
MESAU_RS19375	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MESAU_RS19400	COG0438	transferase activity, transferring glycosyl groups
MESAU_RS19410	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
MESAU_RS19415	COG1877	trehalose-phosphatase activity
MESAU_RS19425	COG0758	DNA mediated transformation
MESAU_RS19430	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MESAU_RS19435	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MESAU_RS19440	COG0540	Belongs to the ATCase OTCase family
MESAU_RS19445	COG1960	acyl-CoA dehydrogenase activity
MESAU_RS19460	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MESAU_RS19465	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MESAU_RS19475	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MESAU_RS19485	COG0154	amidase activity
MESAU_RS19490	COG1434	Gram-negative-bacterium-type cell wall biogenesis
MESAU_RS19500	COG1760	l-serine dehydratase
MESAU_RS19510	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MESAU_RS19515	COG1686	Belongs to the peptidase S11 family
MESAU_RS19525	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MESAU_RS19545	COG0537	adenosine 5'-monophosphoramidase activity
MESAU_RS19580	COG0052	Belongs to the universal ribosomal protein uS2 family
MESAU_RS19585	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MESAU_RS19590	COG0583	DNA-binding transcription factor activity
MESAU_RS19600	COG0667	Aldo Keto reductase
MESAU_RS19605	COG0528	UMP kinase activity
MESAU_RS19610	COG0233	cytoplasmic translational termination
MESAU_RS19615	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MESAU_RS19625	COG0750	zinc metalloprotease
MESAU_RS19630	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MESAU_RS19635	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MESAU_RS19640	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MESAU_RS19645	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MESAU_RS19650	COG3494	Protein of unknown function (DUF1009)
MESAU_RS19655	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MESAU_RS19660	COG0372	Belongs to the citrate synthase family
MESAU_RS19665	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MESAU_RS19675	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MESAU_RS19680	COG1802	Transcriptional regulator
MESAU_RS19690	COG1122	ATPase activity
MESAU_RS19695	COG4120	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS19705	COG3483	tryptophan 2,3-dioxygenase activity
MESAU_RS19720	COG0303	'Molybdopterin
MESAU_RS19725	COG0315	cyclic pyranopterin monophosphate synthase activity
MESAU_RS19730	COG0134	indole-3-glycerol-phosphate synthase activity
MESAU_RS19735	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MESAU_RS19745	COG0149	triose-phosphate isomerase activity
MESAU_RS19760	COG0504	CTP synthase activity
MESAU_RS19775	COG1953	Uracil, thiamine, allantoin
MESAU_RS19780	COG0583	DNA-binding transcription factor activity
MESAU_RS19785	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MESAU_RS19790	COG2267	carboxylic ester hydrolase activity
MESAU_RS19795	COG0747	negative chemotaxis
MESAU_RS19800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MESAU_RS19810	COG0444	Belongs to the ABC transporter superfamily
MESAU_RS19815	COG4608	Belongs to the ABC transporter superfamily
MESAU_RS19865	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MESAU_RS19870	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MESAU_RS19870	COG2010	Cytochrome c
MESAU_RS19875	COG2010	Cytochrome c
MESAU_RS19880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MESAU_RS19900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MESAU_RS19915	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MESAU_RS19920	COG2202	Pas domain
MESAU_RS19920	COG2205	protein histidine kinase activity
MESAU_RS19925	COG1525	nuclease
MESAU_RS19930	COG0625	glutathione transferase activity
MESAU_RS19935	COG1573	uracil-dna glycosylase
MESAU_RS19940	COG1522	sequence-specific DNA binding
MESAU_RS19955	COG2084	Dehydrogenase
MESAU_RS19975	COG1763	Mo-molybdopterin cofactor biosynthetic process
MESAU_RS19980	COG0746	molybdenum cofactor guanylyltransferase activity
MESAU_RS20000	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MESAU_RS20015	COG1846	Transcriptional regulator
MESAU_RS20030	COG1309	transcriptional regulator
MESAU_RS20035	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS20065	COG0546	phosphoglycolate phosphatase activity
MESAU_RS20070	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MESAU_RS20085	COG2239	Acts as a magnesium transporter
MESAU_RS20090	COG4178	(ABC) transporter
MESAU_RS20100	COG4166	transmembrane transport
MESAU_RS20115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MESAU_RS20130	COG1183	phosphatidylcholine synthase activity
MESAU_RS20140	COG3845	ABC transporter
MESAU_RS20145	COG4603	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS20150	COG1079	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS20165	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MESAU_RS20170	COG0861	Integral membrane protein TerC family
MESAU_RS20215	COG1686	Belongs to the peptidase S11 family
MESAU_RS20220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MESAU_RS20230	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MESAU_RS20235	COG0084	hydrolase, TatD family'
MESAU_RS20240	COG1234	tRNA 3'-trailer cleavage
MESAU_RS20270	COG0670	Belongs to the BI1 family
MESAU_RS20295	COG3956	TIGRFAM MazG family protein
MESAU_RS20300	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MESAU_RS20305	COG1923	regulation of RNA biosynthetic process
MESAU_RS20310	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MESAU_RS20315	COG2204	response regulator
MESAU_RS20320	COG5000	phosphorelay sensor kinase activity
MESAU_RS20325	COG2204	response regulator
MESAU_RS20330	COG3852	Histidine kinase
MESAU_RS20340	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MESAU_RS20340	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MESAU_RS20345	COG1546	Belongs to the CinA family
MESAU_RS20350	COG2867	negative regulation of translational initiation
MESAU_RS20355	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MESAU_RS20365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MESAU_RS20380	COG0508	dehydrogenase complex catalyzes the overall conversion of
MESAU_RS20385	COG0508	dehydrogenase complex catalyzes the overall conversion of
MESAU_RS20385	COG0022	dehydrogenase e1 component
MESAU_RS20390	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MESAU_RS20400	COG0148	phosphopyruvate hydratase activity
MESAU_RS20415	COG2877	3-deoxy-8-phosphooctulonate synthase activity
MESAU_RS20435	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MESAU_RS20440	COG0737	Belongs to the 5'-nucleotidase family
MESAU_RS20445	COG1252	NADH dehydrogenase
MESAU_RS20450	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MESAU_RS20455	COG1522	sequence-specific DNA binding
MESAU_RS20460	COG0686	Belongs to the AlaDH PNT family
MESAU_RS20480	COG2897	thiosulfate sulfurtransferase activity
MESAU_RS20485	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MESAU_RS20495	COG0300	oxidoreductase activity
MESAU_RS20505	COG0513	Belongs to the DEAD box helicase family
MESAU_RS20510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MESAU_RS20515	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MESAU_RS20515	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MESAU_RS20520	COG0347	Belongs to the P(II) protein family
MESAU_RS20525	COG0174	glutamine synthetase
MESAU_RS20535	COG0174	glutamine synthetase
MESAU_RS20565	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MESAU_RS20580	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MESAU_RS20595	COG0203	ribosomal protein L17
MESAU_RS20600	COG0202	RNA polymerase activity
MESAU_RS20605	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MESAU_RS20610	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MESAU_RS20615	COG0563	adenylate kinase activity
MESAU_RS20625	COG0200	Binds to the 23S rRNA
MESAU_RS20630	COG1841	ribosomal large subunit assembly
MESAU_RS20635	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MESAU_RS20640	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MESAU_RS20645	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MESAU_RS20650	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MESAU_RS20655	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MESAU_RS20660	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MESAU_RS20665	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MESAU_RS20670	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MESAU_RS20675	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MESAU_RS20680	COG0255	Belongs to the universal ribosomal protein uL29 family
MESAU_RS20685	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MESAU_RS20690	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MESAU_RS20695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MESAU_RS20700	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MESAU_RS20705	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MESAU_RS20710	COG0089	rRNA binding
MESAU_RS20715	COG0088	Forms part of the polypeptide exit tunnel
MESAU_RS20720	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MESAU_RS20725	COG0051	transcription antitermination factor activity, RNA binding
MESAU_RS20730	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MESAU_RS20735	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MESAU_RS20740	COG0049	tRNA binding
MESAU_RS20745	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MESAU_RS20760	COG4122	O-methyltransferase activity
MESAU_RS20765	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MESAU_RS20770	COG0085	RNA polymerase activity
MESAU_RS20775	COG0222	ribosome binding
MESAU_RS20780	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MESAU_RS20785	COG0081	regulation of translation
MESAU_RS20790	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MESAU_RS20800	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MESAU_RS20820	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MESAU_RS20830	COG2261	transglycosylase associated protein
MESAU_RS20850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MESAU_RS20855	COG2084	Dehydrogenase
MESAU_RS20860	COG3622	Belongs to the hyi family
MESAU_RS20865	COG3960	tartronate-semialdehyde synthase activity
MESAU_RS20870	COG1414	Transcriptional regulator
MESAU_RS20905	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MESAU_RS20915	COG1177	transmembrane transport
MESAU_RS20920	COG3842	ATPase activity
MESAU_RS20925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MESAU_RS20950	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MESAU_RS20955	COG0513	Belongs to the DEAD box helicase family
MESAU_RS20965	COG2885	chlorophyll binding
MESAU_RS20990	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MESAU_RS20995	COG0860	N-Acetylmuramoyl-L-alanine amidase
MESAU_RS21000	COG1530	ribonuclease E activity
MESAU_RS21005	COG2066	Belongs to the glutaminase family
MESAU_RS21010	COG0436	Aminotransferase
MESAU_RS21025	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MESAU_RS21030	COG0511	ligase activity, forming carbon-carbon bonds
MESAU_RS21040	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MESAU_RS21060	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MESAU_RS21065	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MESAU_RS21080	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MESAU_RS21085	COG3811	Belongs to the UPF0386 family
MESAU_RS21160	COG1278	Cold shock
MESAU_RS21165	COG0346	lactoylglutathione lyase activity
MESAU_RS21180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MESAU_RS21195	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MESAU_RS21230	COG0484	heat shock protein binding
MESAU_RS21235	COG0494	nUDIX hydrolase
MESAU_RS21240	COG1902	pentaerythritol trinitrate reductase activity
MESAU_RS21260	COG1546	Belongs to the CinA family
MESAU_RS21260	COG1058	Belongs to the CinA family
MESAU_RS21270	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
MESAU_RS21285	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MESAU_RS21325	COG0586	Pfam SNARE associated Golgi protein
MESAU_RS21340	COG1968	undecaprenyl-diphosphatase activity
MESAU_RS21360	COG2267	carboxylic ester hydrolase activity
MESAU_RS21380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MESAU_RS21385	COG3246	L-lysine catabolic process to acetate
MESAU_RS21405	COG0667	Aldo Keto reductase
MESAU_RS21430	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MESAU_RS21435	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MESAU_RS21435	COG3608	succinylglutamate desuccinylase aspartoacylase
MESAU_RS21455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MESAU_RS21460	COG0683	leucine binding
MESAU_RS21465	COG3191	aminopeptidase activity
MESAU_RS21485	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MESAU_RS21490	COG2514	catechol 2,3-dioxygenase activity
MESAU_RS21515	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MESAU_RS21520	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MESAU_RS21530	COG0047	phosphoribosylformylglycinamidine synthase activity
MESAU_RS21555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MESAU_RS21560	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MESAU_RS21590	COG0483	inositol monophosphate 1-phosphatase activity
MESAU_RS21595	COG0037	tRNA processing
MESAU_RS21600	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MESAU_RS21620	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MESAU_RS21625	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
MESAU_RS21630	COG0538	isocitrate dehydrogenase activity
MESAU_RS21640	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MESAU_RS21645	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MESAU_RS21655	COG2313	pseudouridylate synthase activity
MESAU_RS21665	COG3791	Glutathione-dependent formaldehyde-activating
MESAU_RS21670	COG0316	Belongs to the HesB IscA family
MESAU_RS21675	COG2151	metal-sulfur cluster biosynthetic enzyme
MESAU_RS21680	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MESAU_RS21685	COG0719	Fe-S assembly protein
MESAU_RS21690	COG0396	ATPase activity
MESAU_RS21695	COG0719	Fe-S assembly protein
MESAU_RS21705	COG2945	thiolester hydrolase activity
MESAU_RS21710	COG0671	phosphoesterase, PA-phosphatase related
MESAU_RS21715	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MESAU_RS21720	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MESAU_RS21730	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MESAU_RS21745	COG0739	heme binding
MESAU_RS21765	COG1172	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS21790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MESAU_RS21800	COG3842	ATPase activity
MESAU_RS21810	COG1175	transmembrane transport
MESAU_RS21815	COG0395	ABC-type sugar transport system, permease component
MESAU_RS21825	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MESAU_RS21835	COG0776	regulation of translation
MESAU_RS21845	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MESAU_RS21850	COG0740	serine-type endopeptidase activity
MESAU_RS21860	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MESAU_RS21860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MESAU_RS21865	COG2124	cytochrome p450
MESAU_RS21880	COG1832	CoA-binding protein
MESAU_RS21885	COG1120	ATPase activity
MESAU_RS21905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MESAU_RS21910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MESAU_RS21925	COG0010	Belongs to the arginase family
MESAU_RS21930	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MESAU_RS21940	COG1612	heme a metabolic process
MESAU_RS21970	COG0297	glycogen (starch) synthase activity
MESAU_RS21975	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MESAU_RS21990	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MESAU_RS22015	COG0776	regulation of translation
MESAU_RS22020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MESAU_RS22025	COG0416	fatty acid biosynthetic process
MESAU_RS22040	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MESAU_RS22050	COG1216	Glycosyl transferase, family 2
MESAU_RS22055	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
MESAU_RS22060	COG1174	glycine betaine transport
MESAU_RS22065	COG1125	glycine betaine transport
MESAU_RS22070	COG1174	glycine betaine transport
MESAU_RS22075	COG1732	Glycine betaine
MESAU_RS22085	COG2814	Major facilitator Superfamily
MESAU_RS22090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MESAU_RS22095	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MESAU_RS22105	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MESAU_RS22105	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MESAU_RS22110	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MESAU_RS22120	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MESAU_RS22125	COG0025	NhaP-type Na H and K H
MESAU_RS22130	COG2989	Protein conserved in bacteria
MESAU_RS22155	COG0113	porphobilinogen synthase activity
MESAU_RS22175	COG0667	Aldo Keto reductase
MESAU_RS22240	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
MESAU_RS22250	COG0628	permease
MESAU_RS22255	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MESAU_RS22265	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MESAU_RS22280	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MESAU_RS22310	COG0477	Major facilitator Superfamily
MESAU_RS22315	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MESAU_RS22385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MESAU_RS22390	COG1132	(ABC) transporter
MESAU_RS22395	COG3459	Glycosyltransferase 36 associated
MESAU_RS22405	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MESAU_RS22415	COG2986	histidine ammonia-lyase
MESAU_RS22420	COG1228	amidohydrolase
MESAU_RS22425	COG0402	S-adenosylhomocysteine deaminase activity
MESAU_RS22435	COG0251	oxidation-reduction process
MESAU_RS22445	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MESAU_RS22450	COG0803	Belongs to the bacterial solute-binding protein 9 family
MESAU_RS22490	COG1234	tRNA 3'-trailer cleavage
MESAU_RS22495	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
MESAU_RS22505	COG1063	alcohol dehydrogenase
MESAU_RS22510	COG0156	8-amino-7-oxononanoate synthase activity
MESAU_RS22520	COG0726	polysaccharide deacetylase
MESAU_RS22535	COG1902	pentaerythritol trinitrate reductase activity
MESAU_RS22535	COG0446	pyridine nucleotide-disulphide oxidoreductase
MESAU_RS22540	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MESAU_RS22555	COG4948	Mandelate Racemase Muconate Lactonizing
MESAU_RS22560	COG0446	pyridine nucleotide-disulphide oxidoreductase
MESAU_RS22560	COG1902	pentaerythritol trinitrate reductase activity
MESAU_RS22565	COG0747	negative chemotaxis
MESAU_RS22570	COG5598	trimethylamine methyltransferase
MESAU_RS22575	COG0583	DNA-binding transcription factor activity
MESAU_RS22580	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MESAU_RS22610	COG1663	tetraacyldisaccharide 4'-kinase activity
MESAU_RS22615	COG1519	Transferase
MESAU_RS22630	COG0483	inositol monophosphate 1-phosphatase activity
MESAU_RS22635	COG0312	modulator of DNA gyrase
MESAU_RS22645	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
MESAU_RS22650	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MESAU_RS22660	COG0612	Peptidase, M16
MESAU_RS22665	COG0612	Peptidase, M16
MESAU_RS22670	COG0742	ribosomal rna small subunit methyltransferase
MESAU_RS22680	COG0590	tRNA wobble adenosine to inosine editing
MESAU_RS22690	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MESAU_RS22705	COG0196	riboflavin kinase activity
MESAU_RS22720	COG1280	lysine exporter protein (LysE YggA)
MESAU_RS22735	COG2340	Cysteine-rich secretory protein family
MESAU_RS22740	COG2814	Major facilitator Superfamily
MESAU_RS22745	COG1566	PFAM secretion protein HlyD family protein
MESAU_RS22755	COG1609	Transcriptional regulator
MESAU_RS22760	COG0673	inositol 2-dehydrogenase activity
MESAU_RS22775	COG1129	ABC transporter
MESAU_RS22785	COG2207	Transcriptional regulator
MESAU_RS22785	COG3708	Transcriptional regulator
MESAU_RS22790	COG1846	Transcriptional regulator
MESAU_RS22790	COG0456	acetyltransferase
MESAU_RS22800	COG0277	FAD linked oxidase domain protein
MESAU_RS22830	COG0459	protein refolding
MESAU_RS22840	COG1764	response to oxidative stress
MESAU_RS22850	COG1280	lysine exporter protein (LysE YggA)
MESAU_RS22870	COG1278	Cold shock
MESAU_RS22875	COG4221	oxidoreductase activity
MESAU_RS22900	COG1309	transcriptional regulator
MESAU_RS22905	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS22920	COG0114	fumarate hydratase activity
MESAU_RS22925	COG2259	Doxx family
MESAU_RS22930	COG2259	Doxx family
MESAU_RS22940	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MESAU_RS22950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MESAU_RS22960	COG1126	abc transporter atp-binding protein
MESAU_RS22965	COG0765	amino acid transport
MESAU_RS22970	COG4597	amino acid ABC transporter
MESAU_RS22975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MESAU_RS22990	COG0626	cystathionine gamma-synthase activity
MESAU_RS22995	COG0517	IMP dehydrogenase activity
MESAU_RS23010	COG3794	PFAM blue (type 1) copper domain protein
MESAU_RS23015	COG1024	Enoyl-CoA hydratase
MESAU_RS23030	COG0438	transferase activity, transferring glycosyl groups
MESAU_RS23085	COG0628	permease
MESAU_RS23095	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MESAU_RS23100	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MESAU_RS23140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MESAU_RS23150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MESAU_RS23155	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MESAU_RS23170	COG1473	amidohydrolase
MESAU_RS23180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MESAU_RS23185	COG1522	sequence-specific DNA binding
MESAU_RS23190	COG2072	flavoprotein involved in K transport
MESAU_RS23195	COG0243	molybdopterin cofactor binding
MESAU_RS23200	COG0488	(ABC) transporter
MESAU_RS23205	COG4957	zinc ion binding
MESAU_RS23245	COG0105	UTP biosynthetic process
MESAU_RS23250	COG0314	molybdopterin synthase activity
MESAU_RS23260	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MESAU_RS23265	COG0322	excinuclease ABC activity
MESAU_RS23280	COG0625	glutathione transferase activity
MESAU_RS23300	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MESAU_RS23320	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MESAU_RS23345	COG0463	Glycosyl transferase, family 2
MESAU_RS23375	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MESAU_RS23395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MESAU_RS23400	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MESAU_RS23405	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MESAU_RS23410	COG0194	GDP metabolic process
MESAU_RS23415	COG1561	YicC-like family, N-terminal region
MESAU_RS23420	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MESAU_RS23425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MESAU_RS23430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MESAU_RS23440	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MESAU_RS23445	COG1368	sulfuric ester hydrolase activity
MESAU_RS23455	COG0360	Binds together with S18 to 16S ribosomal RNA
MESAU_RS23460	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MESAU_RS23465	COG0359	binds to the 23S rRNA
MESAU_RS23470	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MESAU_RS23475	COG1742	UPF0060 membrane protein
MESAU_RS23500	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MESAU_RS23505	COG4221	oxidoreductase activity
MESAU_RS23540	COG2197	response regulator
MESAU_RS23555	COG0697	spore germination
MESAU_RS23565	COG0583	DNA-binding transcription factor activity
MESAU_RS23580	COG1183	phosphatidylcholine synthase activity
MESAU_RS23585	COG0688	phosphatidylethanolamine metabolic process
MESAU_RS23600	COG5265	(ABC) transporter
MESAU_RS23610	COG1652	LysM domain
MESAU_RS23625	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS23640	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MESAU_RS23665	COG2852	Protein conserved in bacteria
MESAU_RS23670	COG0215	cysteine-tRNA ligase activity
MESAU_RS23705	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MESAU_RS23710	COG0354	folic acid binding
MESAU_RS23715	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
MESAU_RS23720	COG5001	Diguanylate cyclase
MESAU_RS23730	COG0583	DNA-binding transcription factor activity
MESAU_RS23755	COG1595	DNA-templated transcription, initiation
MESAU_RS23770	COG1381	Involved in DNA repair and RecF pathway recombination
MESAU_RS23780	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MESAU_RS23790	COG0681	Belongs to the peptidase S26 family
MESAU_RS23795	COG0736	holo-[acyl-carrier-protein] synthase activity
MESAU_RS23810	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MESAU_RS23820	COG1758	RNA polymerase activity
MESAU_RS23835	COG1522	sequence-specific DNA binding
MESAU_RS23850	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MESAU_RS23855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MESAU_RS23895	COG0457	Tetratricopeptide repeat
MESAU_RS23900	COG0457	Tetratricopeptide repeat
MESAU_RS23905	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MESAU_RS23915	COG1254	Belongs to the acylphosphatase family
MESAU_RS23925	COG1960	acyl-CoA dehydrogenase activity
MESAU_RS23930	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MESAU_RS23935	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
MESAU_RS23970	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MESAU_RS24005	COG0697	spore germination
MESAU_RS24010	COG0308	aminopeptidase N
MESAU_RS24015	COG2202	Pas domain
MESAU_RS24015	COG2205	protein histidine kinase activity
MESAU_RS24025	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MESAU_RS24035	COG0745	RESPONSE REGULATOR receiver
MESAU_RS24040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MESAU_RS24045	COG3088	subunit of a heme lyase
MESAU_RS24050	COG1138	Cytochrome C-type biogenesis protein
MESAU_RS24055	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
MESAU_RS24060	COG4235	cytochrome complex assembly
MESAU_RS24115	COG3842	ATPase activity
MESAU_RS24135	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MESAU_RS24160	COG3409	Peptidoglycan-binding domain 1 protein
MESAU_RS24160	COG3429	Glucose-6-phosphate dehydrogenase subunit
MESAU_RS24165	COG2205	protein histidine kinase activity
MESAU_RS24175	COG2166	iron-sulfur cluster assembly
MESAU_RS24205	COG2010	Cytochrome c
MESAU_RS24210	COG3909	cytochrome
MESAU_RS24215	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MESAU_RS24220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MESAU_RS24230	COG1376	ErfK ybiS ycfS ynhG family protein
MESAU_RS24235	COG0433	COG0433 Predicted ATPase
MESAU_RS24255	COG3654	unkown
MESAU_RS24260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MESAU_RS24275	COG0183	Belongs to the thiolase family
MESAU_RS24280	COG1309	transcriptional regulator
MESAU_RS24285	COG3119	arylsulfatase activity
MESAU_RS24295	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MESAU_RS24300	COG1012	belongs to the aldehyde dehydrogenase family
MESAU_RS24310	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MESAU_RS24340	COG4172	Belongs to the ABC transporter superfamily
MESAU_RS24345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MESAU_RS24350	COG0601	transmembrane transport
MESAU_RS24355	COG4166	transmembrane transport
MESAU_RS24370	COG0366	Alpha amylase catalytic
MESAU_RS24375	COG1523	belongs to the glycosyl hydrolase 13 family
MESAU_RS24380	COG0033	Phosphoglucomutase
MESAU_RS24385	COG0297	glycogen (starch) synthase activity
MESAU_RS24390	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MESAU_RS24395	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MESAU_RS24400	COG0058	SHG alpha-glucan phosphorylase activity
MESAU_RS24445	COG1218	3'(2'),5'-bisphosphate nucleotidase
MESAU_RS24455	COG0175	sulfate reduction
MESAU_RS24460	COG3307	-O-antigen
MESAU_RS24470	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MESAU_RS24485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MESAU_RS24520	COG0438	transferase activity, transferring glycosyl groups
MESAU_RS24530	COG2813	Specifically methylates the guanine in position
MESAU_RS24540	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MESAU_RS24560	COG1091	dTDP-4-dehydrorhamnose reductase activity
MESAU_RS24565	COG1088	dTDP-glucose 4,6-dehydratase activity
MESAU_RS24570	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
MESAU_RS24575	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MESAU_RS24590	COG0489	protein tyrosine kinase activity
MESAU_RS24615	COG0438	transferase activity, transferring glycosyl groups
MESAU_RS24635	COG2226	methyltransferase
MESAU_RS24640	COG0438	transferase activity, transferring glycosyl groups
MESAU_RS24660	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MESAU_RS24665	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MESAU_RS24685	COG1268	BioY protein
MESAU_RS24710	COG0574	Belongs to the PEP-utilizing enzyme family
MESAU_RS24710	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MESAU_RS24780	COG1196	nuclear chromosome segregation
MESAU_RS24785	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MESAU_RS24795	COG1194	a g-specific adenine glycosylase
MESAU_RS24805	COG2189	Belongs to the N(4) N(6)-methyltransferase family
MESAU_RS24810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MESAU_RS24825	COG0612	Peptidase, M16
MESAU_RS24830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MESAU_RS24850	COG1678	Uncharacterized ACR, COG1678
MESAU_RS24860	COG0678	peroxiredoxin activity
MESAU_RS24885	COG0328	RNA-DNA hybrid ribonuclease activity
MESAU_RS24890	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MESAU_RS24895	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MESAU_RS24900	COG3346	SURF1 family
MESAU_RS24915	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
MESAU_RS24925	COG0109	protoheme IX farnesyltransferase activity
MESAU_RS24930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MESAU_RS24935	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MESAU_RS24945	COG0312	modulator of DNA gyrase
MESAU_RS24955	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MESAU_RS24975	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MESAU_RS24980	COG1741	Belongs to the pirin family
MESAU_RS24990	COG1722	exodeoxyribonuclease VII activity
MESAU_RS24995	COG0123	including yeast histone deacetylase and acetoin utilization protein
MESAU_RS25005	COG1309	transcriptional regulator
MESAU_RS25020	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MESAU_RS25030	COG0406	alpha-ribazole phosphatase activity
MESAU_RS25035	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MESAU_RS25040	COG0484	heat shock protein binding
MESAU_RS25050	COG0259	pyridoxamine-phosphate oxidase activity
MESAU_RS25055	COG1024	Enoyl-CoA hydratase
MESAU_RS25060	COG1960	acyl-CoA dehydrogenase activity
MESAU_RS25075	COG0151	Belongs to the GarS family
MESAU_RS25085	COG0583	DNA-binding transcription factor activity
MESAU_RS25090	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MESAU_RS25100	COG0277	FAD linked oxidase domain protein
MESAU_RS25105	COG0009	L-threonylcarbamoyladenylate synthase
MESAU_RS25125	COG0751	glycine-tRNA ligase activity
MESAU_RS25130	COG0752	glycyl-tRNA synthetase alpha subunit
MESAU_RS25160	COG0142	geranyltranstransferase activity
MESAU_RS25185	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MESAU_RS25190	COG0521	Mo-molybdopterin cofactor biosynthetic process
MESAU_RS25205	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MESAU_RS25210	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MESAU_RS25215	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MESAU_RS25220	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MESAU_RS25225	COG0356	it plays a direct role in the translocation of protons across the membrane
MESAU_RS25240	COG2814	Major facilitator Superfamily
MESAU_RS25245	COG0583	DNA-binding transcription factor activity
MESAU_RS25250	COG1160	GTP binding
MESAU_RS25255	COG2976	Protein conserved in bacteria
MESAU_RS25265	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
MESAU_RS25270	COG0477	Major facilitator Superfamily
MESAU_RS25280	COG0583	DNA-binding transcription factor activity
MESAU_RS25285	COG2309	aminopeptidase activity
MESAU_RS25295	COG1393	Belongs to the ArsC family
MESAU_RS25300	COG0640	Transcriptional regulator
MESAU_RS25330	COG1172	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS25345	COG1309	transcriptional regulator
MESAU_RS25360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MESAU_RS25365	COG0583	DNA-binding transcription factor activity
MESAU_RS25380	COG4948	Mandelate Racemase Muconate Lactonizing
MESAU_RS25385	COG4948	Mandelate Racemase Muconate Lactonizing
MESAU_RS25390	COG0747	negative chemotaxis
MESAU_RS25395	COG0601	transmembrane transport
MESAU_RS25400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MESAU_RS25415	COG0747	negative chemotaxis
MESAU_RS25425	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS25430	COG2113	Glycine betaine
MESAU_RS25435	COG4175	Glycine betaine
MESAU_RS25435	COG0517	IMP dehydrogenase activity
MESAU_RS25440	COG4176	ABC-type proline glycine betaine transport system permease component
MESAU_RS25470	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MESAU_RS25490	COG0531	amino acid
MESAU_RS25505	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MESAU_RS25510	COG2218	PFAM glutamate synthase alpha subunit domain protein
MESAU_RS25515	COG0069	glutamate synthase activity
MESAU_RS25525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MESAU_RS25530	COG4311	Sarcosine oxidase, delta subunit
MESAU_RS25540	COG0446	pyridine nucleotide-disulphide oxidoreductase
MESAU_RS25540	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MESAU_RS25550	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MESAU_RS25575	COG0318	PFAM AMP-dependent synthetase and ligase
MESAU_RS25580	COG2390	Transcriptional regulator
MESAU_RS25585	COG3347	Dehydrogenase
MESAU_RS25585	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS25600	COG1879	ABC-type sugar transport system periplasmic component
MESAU_RS25610	COG1129	ABC transporter
MESAU_RS25620	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MESAU_RS25630	COG0287	Prephenate dehydrogenase
MESAU_RS25635	COG1850	ribulose-bisphosphate carboxylase activity
MESAU_RS25640	COG2186	Transcriptional regulator
MESAU_RS25645	COG1879	ABC-type sugar transport system periplasmic component
MESAU_RS25650	COG1129	ABC transporter
MESAU_RS25660	COG0287	Prephenate dehydrogenase
MESAU_RS25675	COG1129	ABC transporter
MESAU_RS25680	COG1172	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS25685	COG0673	inositol 2-dehydrogenase activity
MESAU_RS25700	COG1850	ribulose-bisphosphate carboxylase activity
MESAU_RS25720	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MESAU_RS25725	COG2376	Dihydroxyacetone kinase
MESAU_RS25730	COG1461	Dihydroxyacetone kinase
MESAU_RS25735	COG0698	ribose 5-phosphate isomerase
MESAU_RS25740	COG0149	triose-phosphate isomerase activity
MESAU_RS25765	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MESAU_RS25775	COG3842	ATPase activity
MESAU_RS25790	COG1175	transmembrane transport
MESAU_RS25795	COG1653	transport
MESAU_RS25805	COG1285	pathogenesis
MESAU_RS25810	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MESAU_RS25825	COG0174	glutamine synthetase
MESAU_RS25830	COG1737	Transcriptional regulator
MESAU_RS25835	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MESAU_RS25840	COG2971	BadF BadG BcrA BcrD
MESAU_RS25845	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MESAU_RS25850	COG0747	negative chemotaxis
MESAU_RS25860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MESAU_RS25875	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MESAU_RS25885	COG2204	response regulator
MESAU_RS25890	COG4191	Histidine kinase
MESAU_RS25895	COG1301	dicarboxylic acid transport
MESAU_RS25900	COG1940	carbohydrate kinase activity
MESAU_RS25920	COG0673	inositol 2-dehydrogenase activity
MESAU_RS25930	COG0395	ABC-type sugar transport system, permease component
MESAU_RS25935	COG1175	transmembrane transport
MESAU_RS25950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MESAU_RS25960	COG1349	DNA-binding transcription factor activity
MESAU_RS25970	COG0657	acetylesterase activity
MESAU_RS25980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MESAU_RS25985	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
MESAU_RS26020	COG3842	ATPase activity
MESAU_RS26025	COG1176	ABC-type spermidine putrescine transport system, permease component I
MESAU_RS26030	COG1177	transmembrane transport
MESAU_RS26035	COG0277	FAD linked oxidase domain protein
MESAU_RS26050	COG0667	Aldo Keto reductase
MESAU_RS26080	COG0559	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS26090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MESAU_RS26095	COG1802	Transcriptional regulator
MESAU_RS26100	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MESAU_RS26110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MESAU_RS26160	COG0583	DNA-binding transcription factor activity
MESAU_RS26180	COG2706	6-phosphogluconolactonase activity
MESAU_RS26215	COG1175	transmembrane transport
MESAU_RS26220	COG0395	ABC-type sugar transport system, permease component
MESAU_RS26225	COG3842	ATPase activity
MESAU_RS26230	COG4948	Mandelate Racemase Muconate Lactonizing
MESAU_RS26235	COG3254	rhamnose metabolic process
MESAU_RS26270	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MESAU_RS26275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MESAU_RS26280	COG1012	belongs to the aldehyde dehydrogenase family
MESAU_RS26290	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MESAU_RS26305	COG1349	DNA-binding transcription factor activity
MESAU_RS26310	COG3608	succinylglutamate desuccinylase aspartoacylase
MESAU_RS26315	COG0006	proline dipeptidase activity
MESAU_RS26320	COG2423	ornithine cyclodeaminase activity
MESAU_RS26325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MESAU_RS26335	COG0765	amino acid transport
MESAU_RS26340	COG0765	amino acid transport
MESAU_RS26345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MESAU_RS26350	COG1126	abc transporter atp-binding protein
MESAU_RS26355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MESAU_RS26360	COG1522	sequence-specific DNA binding
MESAU_RS26365	COG1012	belongs to the aldehyde dehydrogenase family
MESAU_RS26370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MESAU_RS26375	COG0604	alcohol dehydrogenase
MESAU_RS26375	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS26375	COG3321	synthase
MESAU_RS26380	COG2986	histidine ammonia-lyase
MESAU_RS26385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MESAU_RS26390	COG1132	(ABC) transporter
MESAU_RS26395	COG1132	(ABC) transporter
MESAU_RS26400	COG0477	Major facilitator Superfamily
MESAU_RS26435	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MESAU_RS26440	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS26445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MESAU_RS26450	COG0431	NADPH-dependent FMN reductase
MESAU_RS26460	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS26465	COG3769	mannosylglycerate metabolic process
MESAU_RS26485	COG1793	dna ligase
MESAU_RS26490	COG3685	Protein conserved in bacteria
MESAU_RS26505	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MESAU_RS26510	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MESAU_RS26515	COG2080	2 iron, 2 sulfur cluster binding
MESAU_RS26535	COG1295	ribonuclease BN
MESAU_RS26545	COG2814	Major facilitator Superfamily
MESAU_RS26600	COG1914	H( )-stimulated, divalent metal cation uptake system
MESAU_RS26630	COG0300	oxidoreductase activity
MESAU_RS26670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MESAU_RS26675	COG1032	radical SAM domain protein
MESAU_RS26700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MESAU_RS26715	COG1260	myo-inositol-1-phosphate synthase
MESAU_RS26765	COG0753	catalase activity
MESAU_RS26815	COG4964	Belongs to the GSP D family
MESAU_RS26860	COG0657	acetylesterase activity
MESAU_RS26870	COG1454	alcohol dehydrogenase
MESAU_RS26880	COG1129	ABC transporter
MESAU_RS26885	COG1172	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS26890	COG1879	ABC-type sugar transport system periplasmic component
MESAU_RS26900	COG4948	Mandelate Racemase Muconate Lactonizing
MESAU_RS26910	COG4948	Mandelate Racemase Muconate Lactonizing
MESAU_RS26925	COG1653	transport
MESAU_RS26940	COG3842	ATPase activity
MESAU_RS26945	COG4948	Mandelate Racemase Muconate Lactonizing
MESAU_RS26955	COG0583	DNA-binding transcription factor activity
MESAU_RS26960	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS26965	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS26985	COG1234	tRNA 3'-trailer cleavage
MESAU_RS26995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MESAU_RS27045	COG0717	Belongs to the dCTP deaminase family
MESAU_RS27105	COG2010	Cytochrome c
MESAU_RS27130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MESAU_RS27140	COG2948	multi-organism process
MESAU_RS27165	COG3451	type IV secretory pathway VirB4
MESAU_RS27175	COG3838	Conjugal transfer protein Trbc
MESAU_RS27180	COG4962	Type ii secretion system protein e
MESAU_RS27195	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MESAU_RS27210	COG4959	Type IV secretory pathway protease TraF
MESAU_RS27225	COG1475	DNA binding
MESAU_RS27355	COG0602	queuosine metabolic process
MESAU_RS27360	COG0720	synthase
MESAU_RS27365	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MESAU_RS27385	COG2327	Polysaccharide pyruvyl transferase
MESAU_RS27415	COG3916	Acyl-homoserine-lactone synthase
MESAU_RS27425	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MESAU_RS27430	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MESAU_RS27445	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MESAU_RS27455	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MESAU_RS27465	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MESAU_RS27470	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MESAU_RS27475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MESAU_RS27560	COG0745	RESPONSE REGULATOR receiver
MESAU_RS27615	COG1473	amidohydrolase
MESAU_RS27620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MESAU_RS27630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MESAU_RS27635	COG4215	(ABC) transporter
MESAU_RS27645	COG0010	Belongs to the arginase family
MESAU_RS27660	COG1834	amidinotransferase
MESAU_RS27715	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MESAU_RS27720	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MESAU_RS27725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MESAU_RS27730	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MESAU_RS27740	COG1063	alcohol dehydrogenase
MESAU_RS27750	COG4957	zinc ion binding
MESAU_RS27755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MESAU_RS27765	COG1278	Cold shock
MESAU_RS27775	COG2124	cytochrome p450
MESAU_RS27780	COG1141	Ferredoxin
MESAU_RS27790	COG2124	cytochrome p450
MESAU_RS27795	COG0142	geranyltranstransferase activity
MESAU_RS27805	COG1657	PFAM Prenyltransferase squalene oxidase
MESAU_RS27815	COG1304	FMN binding
MESAU_RS27870	COG1012	belongs to the aldehyde dehydrogenase family
MESAU_RS27890	COG1505	serine-type exopeptidase activity
MESAU_RS27900	COG1476	TRANSCRIPTIONal
MESAU_RS27910	COG2771	luxR family
MESAU_RS27915	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MESAU_RS27925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MESAU_RS27940	COG1522	sequence-specific DNA binding
MESAU_RS27945	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
MESAU_RS27945	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MESAU_RS27965	COG2301	Belongs to the HpcH HpaI aldolase family
MESAU_RS27975	COG3799	methylaspartate ammonia-lyase activity
MESAU_RS28030	COG2843	Capsule synthesis protein
MESAU_RS28035	COG4608	Belongs to the ABC transporter superfamily
MESAU_RS28040	COG0444	Belongs to the ABC transporter superfamily
MESAU_RS28045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MESAU_RS28050	COG0601	transmembrane transport
MESAU_RS28055	COG0747	negative chemotaxis
MESAU_RS28080	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MESAU_RS28085	COG3547	Transposase (IS116 IS110 IS902 family)
MESAU_RS28100	COG0006	proline dipeptidase activity
MESAU_RS28115	COG0765	amino acid transport
MESAU_RS28120	COG1126	abc transporter atp-binding protein
MESAU_RS28180	COG3547	Transposase (IS116 IS110 IS902 family)
MESAU_RS28190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MESAU_RS28195	COG0601	transmembrane transport
MESAU_RS28220	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MESAU_RS28235	COG0765	amino acid transport
MESAU_RS28240	COG0765	amino acid transport
MESAU_RS28275	COG4372	Transposase
MESAU_RS28280	COG1181	Belongs to the D-alanine--D-alanine ligase family
MESAU_RS28285	COG0604	alcohol dehydrogenase
MESAU_RS28290	COG4948	Mandelate Racemase Muconate Lactonizing
MESAU_RS28300	COG1012	belongs to the aldehyde dehydrogenase family
MESAU_RS28305	COG4638	Rieske (2fe-2S)
MESAU_RS28325	COG1181	Belongs to the D-alanine--D-alanine ligase family
MESAU_RS28335	COG1181	Belongs to the D-alanine--D-alanine ligase family
MESAU_RS28375	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MESAU_RS28380	COG1126	abc transporter atp-binding protein
MESAU_RS28440	COG2771	luxR family
MESAU_RS28445	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MESAU_RS28450	COG3383	formate dehydrogenase (NAD+) activity
MESAU_RS28455	COG5420	small protein containing a coiled-coil domain
MESAU_RS28475	COG2755	lipolytic protein G-D-S-L family
MESAU_RS28475	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MESAU_RS28495	COG1433	Dinitrogenase iron-molybdenum cofactor
MESAU_RS28500	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
MESAU_RS28505	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
MESAU_RS28510	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
MESAU_RS28515	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
MESAU_RS28525	COG2814	Major facilitator Superfamily
MESAU_RS28540	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MESAU_RS28550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MESAU_RS28555	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS28560	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
MESAU_RS28565	COG2124	cytochrome p450
MESAU_RS28570	COG3720	iron ion transport
MESAU_RS28575	COG0316	Belongs to the HesB IscA family
MESAU_RS28580	COG1104	cysteine desulfurase activity
MESAU_RS28595	COG2086	electron transfer activity
MESAU_RS28600	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MESAU_RS28605	COG0644	oxidoreductase
MESAU_RS28615	COG0535	radical SAM domain protein
MESAU_RS28620	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MESAU_RS28625	COG5554	nitrogen fixation
MESAU_RS28630	COG5554	nitrogen fixation
MESAU_RS28640	COG1132	(ABC) transporter
MESAU_RS28645	COG1132	(ABC) transporter
MESAU_RS28660	COG3604	Transcriptional regulator
MESAU_RS28665	COG1301	dicarboxylic acid transport
MESAU_RS28680	COG0583	DNA-binding transcription factor activity
MESAU_RS28710	COG0583	DNA-binding transcription factor activity
MESAU_RS28745	COG2192	nodulation
MESAU_RS28835	COG0745	RESPONSE REGULATOR receiver
MESAU_RS28925	COG1304	FMN binding
MESAU_RS28945	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MESAU_RS28975	COG4607	ABC-type enterochelin transport system periplasmic component
MESAU_RS28990	COG4952	isomerase
MESAU_RS28995	COG3347	Dehydrogenase
MESAU_RS28995	COG1028	Short-chain dehydrogenase reductase Sdr
MESAU_RS29000	COG1349	DNA-binding transcription factor activity
MESAU_RS29010	COG1129	ABC transporter
MESAU_RS29015	COG1172	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS29020	COG1172	Belongs to the binding-protein-dependent transport system permease family
MESAU_RS29025	COG3254	rhamnose metabolic process
MESAU_RS29040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MESAU_RS29050	COG0156	8-amino-7-oxononanoate synthase activity
MESAU_RS29055	COG0436	Aminotransferase
MESAU_RS29060	COG1970	mechanosensitive ion channel activity
MESAU_RS29065	COG2205	protein histidine kinase activity
MESAU_RS29065	COG0784	Response regulator, receiver
MESAU_RS29085	COG0167	dihydroorotate dehydrogenase activity
MESAU_RS29090	COG0534	Mate efflux family protein
MESAU_RS29095	COG0123	including yeast histone deacetylase and acetoin utilization protein
MESAU_RS29105	COG0463	Glycosyl transferase, family 2
MESAU_RS29245	COG1129	ABC transporter
MESAU_RS29250	COG4214	carbohydrate transport
MESAU_RS29260	COG0717	Belongs to the dCTP deaminase family
MESAU_RS29275	COG2967	ApaG domain
MESAU_RS29285	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MESAU_RS29290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MESAU_RS29300	COG0598	Magnesium transport protein CorA
MESAU_RS29305	COG0704	Plays a role in the regulation of phosphate uptake
MESAU_RS29310	COG5002	protein histidine kinase activity
MESAU_RS29315	COG2326	polyphosphate kinase activity
MESAU_RS29320	COG1024	Enoyl-CoA hydratase
MESAU_RS29330	COG2197	response regulator
MESAU_RS29345	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
MESAU_RS29370	COG1250	3-hydroxyacyl-CoA dehydrogenase
MESAU_RS29370	COG1024	Enoyl-CoA hydratase
MESAU_RS29375	COG0183	Belongs to the thiolase family
MESAU_RS29380	COG1960	acyl-CoA dehydrogenase activity
MESAU_RS29385	COG1960	acyl-CoA dehydrogenase activity
MESAU_RS29390	COG0789	Transcriptional regulator
MESAU_RS29400	COG0730	response to heat
MESAU_RS29410	COG0443	Heat shock 70 kDa protein
MESAU_RS29420	COG0243	molybdopterin cofactor binding
MESAU_RS29425	COG0437	4 iron, 4 sulfur cluster binding
MESAU_RS29430	COG3302	dmso reductase anchor subunit
MESAU_RS29440	COG1201	RNA secondary structure unwinding
MESAU_RS29445	COG0791	NLP P60 protein
MESAU_RS29455	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MESAU_RS29490	COG4964	Belongs to the GSP D family
MESAU_RS29530	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MESAU_RS29535	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MESAU_RS29540	COG1024	Enoyl-CoA hydratase
MESAU_RS29545	COG0268	Binds directly to 16S ribosomal RNA
MESAU_RS29590	COG1252	NADH dehydrogenase
MESAU_RS29620	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MESAU_RS29620	COG2755	lipolytic protein G-D-S-L family