locus-tag	class	description
R7A2020_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
R7A2020_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
R7A2020_RS00030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
R7A2020_RS00050	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
R7A2020_RS00060	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
R7A2020_RS00065	COG3300	MHYT domain
R7A2020_RS00065	COG5001	Diguanylate cyclase
R7A2020_RS00070	COG2813	Specifically methylates the guanine in position
R7A2020_RS00075	COG1185	polyribonucleotide nucleotidyltransferase activity
R7A2020_RS00080	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
R7A2020_RS00085	COG0598	Magnesium transport protein CorA
R7A2020_RS00090	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
R7A2020_RS00095	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
R7A2020_RS00100	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
R7A2020_RS00115	COG0779	Required for maturation of 30S ribosomal subunits
R7A2020_RS00125	COG0220	tRNA (guanine-N7-)-methyltransferase activity
R7A2020_RS00130	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
R7A2020_RS00135	COG1396	sequence-specific DNA binding
R7A2020_RS00140	COG0815	Transfers the fatty acyl group on membrane lipoproteins
R7A2020_RS00145	COG0583	DNA-binding transcription factor activity
R7A2020_RS00160	COG1253	flavin adenine dinucleotide binding
R7A2020_RS00165	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
R7A2020_RS00170	COG1702	phosphate starvation-inducible protein PhoH
R7A2020_RS00175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
R7A2020_RS00190	COG1214	PFAM Peptidase M22, glycoprotease
R7A2020_RS00230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
R7A2020_RS00235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
R7A2020_RS00240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
R7A2020_RS00245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
R7A2020_RS00255	COG0444	Belongs to the ABC transporter superfamily
R7A2020_RS00265	COG0601	transmembrane transport
R7A2020_RS00270	COG0747	negative chemotaxis
R7A2020_RS00275	COG2951	lytic endotransglycosylase activity
R7A2020_RS00280	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
R7A2020_RS00295	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
R7A2020_RS00315	COG2816	NAD+ diphosphatase activity
R7A2020_RS00325	COG0077	Prephenate dehydratase
R7A2020_RS00325	COG1605	Chorismate mutase
R7A2020_RS00330	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
R7A2020_RS00335	COG3474	cytochrome
R7A2020_RS00340	COG4166	transmembrane transport
R7A2020_RS00345	COG4166	transmembrane transport
R7A2020_RS00350	COG4174	ABC transporter (Permease)
R7A2020_RS00355	COG4239	(ABC) transporter, permease
R7A2020_RS00360	COG4172	Belongs to the ABC transporter superfamily
R7A2020_RS00365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
R7A2020_RS00390	COG1793	dna ligase
R7A2020_RS00470	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
R7A2020_RS00485	COG0601	transmembrane transport
R7A2020_RS00490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
R7A2020_RS00495	COG0444	Belongs to the ABC transporter superfamily
R7A2020_RS00525	COG1024	Enoyl-CoA hydratase
R7A2020_RS00530	COG1960	acyl-CoA dehydrogenase activity
R7A2020_RS00540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
R7A2020_RS00550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
R7A2020_RS00560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
R7A2020_RS00565	COG4608	Belongs to the ABC transporter superfamily
R7A2020_RS00570	COG0444	Belongs to the ABC transporter superfamily
R7A2020_RS00575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
R7A2020_RS00580	COG0601	transmembrane transport
R7A2020_RS00585	COG0747	negative chemotaxis
R7A2020_RS00590	COG0318	PFAM AMP-dependent synthetase and ligase
R7A2020_RS00600	COG0546	phosphoglycolate phosphatase activity
R7A2020_RS00605	COG0166	Belongs to the GPI family
R7A2020_RS00610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
R7A2020_RS00635	COG0129	dihydroxy-acid dehydratase activity
R7A2020_RS00645	COG0489	protein tyrosine kinase activity
R7A2020_RS00655	COG3706	GGDEF domain
R7A2020_RS00660	COG0583	DNA-binding transcription factor activity
R7A2020_RS00675	COG3383	formate dehydrogenase (NAD+) activity
R7A2020_RS00680	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
R7A2020_RS00690	COG2197	response regulator
R7A2020_RS00715	COG1177	transmembrane transport
R7A2020_RS00720	COG1176	ABC-type spermidine putrescine transport system, permease component I
R7A2020_RS00725	COG3842	ATPase activity
R7A2020_RS00730	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
R7A2020_RS00735	COG2226	methyltransferase
R7A2020_RS00755	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
R7A2020_RS00760	COG0745	RESPONSE REGULATOR receiver
R7A2020_RS00770	COG1349	DNA-binding transcription factor activity
R7A2020_RS00785	COG2226	methyltransferase
R7A2020_RS00795	COG3152	Membrane
R7A2020_RS00800	COG0697	spore germination
R7A2020_RS00805	COG0402	S-adenosylhomocysteine deaminase activity
R7A2020_RS00810	COG1132	(ABC) transporter
R7A2020_RS00815	COG0129	dihydroxy-acid dehydratase activity
R7A2020_RS00835	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
R7A2020_RS00840	COG0596	Alpha beta hydrolase
R7A2020_RS00850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
R7A2020_RS00855	COG0154	amidase activity
R7A2020_RS00860	COG0121	glutamine amidotransferase
R7A2020_RS00870	COG1522	sequence-specific DNA binding
R7A2020_RS00875	COG0756	dUTP diphosphatase activity
R7A2020_RS00880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
R7A2020_RS00905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
R7A2020_RS00915	COG3706	GGDEF domain
R7A2020_RS00920	COG0281	malic enzyme
R7A2020_RS00920	COG0280	phosphate acetyltransferase
R7A2020_RS00925	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
R7A2020_RS00930	COG0656	L-ascorbic acid biosynthetic process
R7A2020_RS00950	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
R7A2020_RS00955	COG0728	peptidoglycan biosynthetic process
R7A2020_RS00970	COG0180	Tryptophanyl-tRNA synthetase
R7A2020_RS00980	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
R7A2020_RS00985	COG1388	LysM domain
R7A2020_RS00985	COG1376	ErfK ybiS ycfS ynhG family protein
R7A2020_RS01015	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
R7A2020_RS01020	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
R7A2020_RS01030	COG1643	Atp-dependent helicase
R7A2020_RS01050	COG1175	transmembrane transport
R7A2020_RS01080	COG1461	Dihydroxyacetone kinase
R7A2020_RS01105	COG2376	Dihydroxyacetone kinase
R7A2020_RS01135	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS01140	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS01145	COG0583	DNA-binding transcription factor activity
R7A2020_RS01150	COG3206	protein involved in exopolysaccharide biosynthesis
R7A2020_RS01150	COG0489	protein tyrosine kinase activity
R7A2020_RS01155	COG1210	Utp--glucose-1-phosphate uridylyltransferase
R7A2020_RS01160	COG1215	transferase activity, transferring glycosyl groups
R7A2020_RS01165	COG1215	transferase activity, transferring glycosyl groups
R7A2020_RS01170	COG1215	transferase activity, transferring glycosyl groups
R7A2020_RS01175	COG0438	transferase activity, transferring glycosyl groups
R7A2020_RS01180	COG2244	polysaccharide biosynthetic process
R7A2020_RS01185	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
R7A2020_RS01210	COG2273	Hydrolase Family 16
R7A2020_RS01220	COG1215	transferase activity, transferring glycosyl groups
R7A2020_RS01245	COG0367	asparagine synthase
R7A2020_RS01255	COG1132	(ABC) transporter
R7A2020_RS01265	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
R7A2020_RS01270	COG1596	polysaccharide export
R7A2020_RS01275	COG3307	-O-antigen
R7A2020_RS01280	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS01285	COG4647	ligase activity
R7A2020_RS01290	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
R7A2020_RS01295	COG0145	ligase activity
R7A2020_RS01305	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS01330	COG1012	belongs to the aldehyde dehydrogenase family
R7A2020_RS01340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
R7A2020_RS01350	COG0446	pyridine nucleotide-disulphide oxidoreductase
R7A2020_RS01350	COG0404	The glycine cleavage system catalyzes the degradation of glycine
R7A2020_RS01365	COG0431	NADPH-dependent FMN reductase
R7A2020_RS01375	COG0410	ABC transporter
R7A2020_RS01395	COG0411	ABC transporter
R7A2020_RS01410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
R7A2020_RS01425	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
R7A2020_RS01430	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
R7A2020_RS01435	COG0539	negative regulation of cytoplasmic translation
R7A2020_RS01475	COG4215	(ABC) transporter
R7A2020_RS01485	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
R7A2020_RS01495	COG4977	sequence-specific DNA binding
R7A2020_RS01570	COG5001	Diguanylate cyclase
R7A2020_RS01600	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
R7A2020_RS01605	COG1063	alcohol dehydrogenase
R7A2020_RS01615	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
R7A2020_RS01620	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
R7A2020_RS01635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
R7A2020_RS01640	COG1609	Transcriptional regulator
R7A2020_RS01665	COG0523	cobalamin synthesis protein
R7A2020_RS01700	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
R7A2020_RS01705	COG0174	glutamine synthetase
R7A2020_RS01710	COG1573	uracil-dna glycosylase
R7A2020_RS01720	COG4702	Belongs to the UPF0303 family
R7A2020_RS01725	COG0402	S-adenosylhomocysteine deaminase activity
R7A2020_RS01735	COG0583	DNA-binding transcription factor activity
R7A2020_RS01740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
R7A2020_RS01755	COG1529	Aldehyde oxidase and xanthine dehydrogenase
R7A2020_RS01765	COG2351	hydroxyisourate hydrolase activity
R7A2020_RS01770	COG3648	Uricase
R7A2020_RS01770	COG3195	allantoin biosynthetic process
R7A2020_RS01775	COG3257	ureidoglycine aminohydrolase activity
R7A2020_RS01780	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
R7A2020_RS01795	COG0747	negative chemotaxis
R7A2020_RS01800	COG0601	transmembrane transport
R7A2020_RS01805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
R7A2020_RS01815	COG4166	transmembrane transport
R7A2020_RS01820	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
R7A2020_RS01830	COG1595	DNA-templated transcription, initiation
R7A2020_RS01840	COG1404	Belongs to the peptidase S8 family
R7A2020_RS01845	COG1609	Transcriptional regulator
R7A2020_RS01850	COG1653	transport
R7A2020_RS01855	COG1175	transmembrane transport
R7A2020_RS01860	COG0395	ABC-type sugar transport system, permease component
R7A2020_RS01865	COG0366	Alpha amylase catalytic
R7A2020_RS01870	COG3842	ATPase activity
R7A2020_RS01895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
R7A2020_RS01910	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
R7A2020_RS01915	COG0745	RESPONSE REGULATOR receiver
R7A2020_RS01920	COG2205	protein histidine kinase activity
R7A2020_RS01925	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
R7A2020_RS01930	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
R7A2020_RS01930	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
R7A2020_RS01940	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
R7A2020_RS01945	COG2205	protein histidine kinase activity
R7A2020_RS01950	COG3178	'Phosphotransferase
R7A2020_RS01955	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
R7A2020_RS01960	COG2887	Belongs to the helicase family. UvrD subfamily
R7A2020_RS01965	COG1074	ATP-dependent DNA helicase activity
R7A2020_RS02000	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
R7A2020_RS02005	COG0159	tryptophan synthase activity
R7A2020_RS02010	COG0133	tryptophan synthase activity
R7A2020_RS02015	COG0135	phosphoribosylanthranilate isomerase activity
R7A2020_RS02035	COG3135	benzoate transporter
R7A2020_RS02045	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
R7A2020_RS02055	COG0291	Belongs to the bacterial ribosomal protein bL35 family
R7A2020_RS02060	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
R7A2020_RS02065	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
R7A2020_RS02075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
R7A2020_RS02075	COG0072	phenylalanine-tRNA ligase activity
R7A2020_RS02085	COG0667	Aldo Keto reductase
R7A2020_RS02135	COG1250	3-hydroxyacyl-CoA dehydrogenase
R7A2020_RS02145	COG3246	L-lysine catabolic process to acetate
R7A2020_RS02150	COG4977	sequence-specific DNA binding
R7A2020_RS02160	COG2115	Belongs to the xylose isomerase family
R7A2020_RS02170	COG1070	Carbohydrate kinase
R7A2020_RS02185	COG1280	lysine exporter protein (LysE YggA)
R7A2020_RS02195	COG1388	LysM domain
R7A2020_RS02195	COG1376	ErfK ybiS ycfS ynhG family protein
R7A2020_RS02200	COG0205	6-phosphofructokinase activity
R7A2020_RS02215	COG1072	(Pantothenic acid kinase))
R7A2020_RS02220	COG0140	phosphoribosyl-ATP diphosphatase activity
R7A2020_RS02225	COG0107	imidazoleglycerol-phosphate synthase activity
R7A2020_RS02235	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
R7A2020_RS02245	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
R7A2020_RS02255	COG0131	Imidazoleglycerol-phosphate dehydratase
R7A2020_RS02260	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
R7A2020_RS02275	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
R7A2020_RS02300	COG1609	Transcriptional regulator
R7A2020_RS02310	COG1172	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS02320	COG0673	inositol 2-dehydrogenase activity
R7A2020_RS02325	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS02330	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
R7A2020_RS02355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
R7A2020_RS02360	COG3962	Belongs to the TPP enzyme family
R7A2020_RS02365	COG1082	Xylose isomerase domain protein TIM barrel
R7A2020_RS02375	COG3718	enzyme involved in inositol metabolism
R7A2020_RS02380	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
R7A2020_RS02385	COG3454	Phosphonate metabolism
R7A2020_RS02390	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
R7A2020_RS02405	COG1172	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS02420	COG1609	Transcriptional regulator
R7A2020_RS02445	COG1686	Belongs to the peptidase S11 family
R7A2020_RS02460	COG1072	(Pantothenic acid kinase))
R7A2020_RS02470	COG0625	glutathione transferase activity
R7A2020_RS02485	COG0829	nickel cation binding
R7A2020_RS02490	COG0831	urea catabolic process
R7A2020_RS02495	COG3813	Protein conserved in bacteria
R7A2020_RS02505	COG0832	Belongs to the urease beta subunit family
R7A2020_RS02520	COG0804	urea catabolic process
R7A2020_RS02530	COG0625	glutathione transferase activity
R7A2020_RS02535	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
R7A2020_RS02540	COG0830	nickel cation binding
R7A2020_RS02550	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
R7A2020_RS02560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
R7A2020_RS02575	COG0583	DNA-binding transcription factor activity
R7A2020_RS02585	COG1175	transmembrane transport
R7A2020_RS02590	COG0395	ABC-type sugar transport system, permease component
R7A2020_RS02620	COG3842	ATPase activity
R7A2020_RS02625	COG1063	alcohol dehydrogenase
R7A2020_RS02630	COG0395	ABC-type sugar transport system, permease component
R7A2020_RS02650	COG0534	Mate efflux family protein
R7A2020_RS02670	COG0765	amino acid transport
R7A2020_RS02675	COG0765	amino acid transport
R7A2020_RS02690	COG0583	DNA-binding transcription factor activity
R7A2020_RS02695	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
R7A2020_RS02715	COG0559	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS02725	COG0411	ABC transporter
R7A2020_RS02740	COG1335	isochorismatase
R7A2020_RS02745	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
R7A2020_RS02770	COG1846	Transcriptional regulator
R7A2020_RS02775	COG0483	inositol monophosphate 1-phosphatase activity
R7A2020_RS02780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
R7A2020_RS02790	COG0628	permease
R7A2020_RS02805	COG2076	Multidrug Resistance protein
R7A2020_RS02835	COG0242	peptide deformylase activity
R7A2020_RS02840	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
R7A2020_RS02850	COG0101	tRNA pseudouridine synthase activity
R7A2020_RS02860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
R7A2020_RS02865	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
R7A2020_RS02885	COG2171	N-acyltransferase activity
R7A2020_RS02900	COG3706	GGDEF domain
R7A2020_RS02915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
R7A2020_RS02940	COG3186	Phenylalanine-4-hydroxylase
R7A2020_RS02945	COG1522	sequence-specific DNA binding
R7A2020_RS02950	COG1032	radical SAM domain protein
R7A2020_RS02955	COG0251	oxidation-reduction process
R7A2020_RS02960	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
R7A2020_RS02980	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
R7A2020_RS02985	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
R7A2020_RS03005	COG0218	Necessary for normal cell division and for the maintenance of normal septation
R7A2020_RS03015	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
R7A2020_RS03020	COG0706	membrane insertase activity
R7A2020_RS03025	COG0594	ribonuclease P activity
R7A2020_RS03030	COG0230	Belongs to the bacterial ribosomal protein bL34 family
R7A2020_RS03035	COG4191	Histidine kinase
R7A2020_RS03055	COG0583	DNA-binding transcription factor activity
R7A2020_RS03070	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS03120	COG1846	Transcriptional regulator
R7A2020_RS03130	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
R7A2020_RS03135	COG2011	ABC-type metal ion transport system permease component
R7A2020_RS03140	COG0404	The glycine cleavage system catalyzes the degradation of glycine
R7A2020_RS03145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
R7A2020_RS03165	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
R7A2020_RS03170	COG1012	belongs to the aldehyde dehydrogenase family
R7A2020_RS03175	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS03180	COG0179	Fumarylacetoacetate (FAA) hydrolase
R7A2020_RS03190	COG0673	inositol 2-dehydrogenase activity
R7A2020_RS03200	COG0395	ABC-type sugar transport system, permease component
R7A2020_RS03205	COG1175	transmembrane transport
R7A2020_RS03215	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
R7A2020_RS03220	COG2971	BadF BadG BcrA BcrD
R7A2020_RS03225	COG2188	Transcriptional regulator
R7A2020_RS03230	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
R7A2020_RS03235	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
R7A2020_RS03240	COG0579	oxidoreductase
R7A2020_RS03245	COG4178	(ABC) transporter
R7A2020_RS03250	COG0318	PFAM AMP-dependent synthetase and ligase
R7A2020_RS03275	COG0443	Heat shock 70 kDa protein
R7A2020_RS03280	COG0484	heat shock protein binding
R7A2020_RS03285	COG3963	phosphatidate phosphatase activity
R7A2020_RS03295	COG0284	orotidine-5'-phosphate decarboxylase activity
R7A2020_RS03305	COG1802	Transcriptional regulator
R7A2020_RS03320	COG3386	PFAM SMP-30 Gluconolaconase
R7A2020_RS03325	COG0800	Aldolase
R7A2020_RS03330	COG3734	2-keto-3-deoxy-galactonokinase
R7A2020_RS03335	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS03340	COG5001	Diguanylate cyclase
R7A2020_RS03360	COG0189	ligase activity
R7A2020_RS03370	COG1309	transcriptional regulator
R7A2020_RS03380	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
R7A2020_RS03420	COG0076	glutamate decarboxylase activity
R7A2020_RS03445	COG3038	cytochrome b561
R7A2020_RS03475	COG0588	phosphoglycerate mutase activity
R7A2020_RS03480	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
R7A2020_RS03485	COG1132	(ABC) transporter
R7A2020_RS03490	COG0837	glucose binding
R7A2020_RS03495	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
R7A2020_RS03505	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
R7A2020_RS03515	COG1968	undecaprenyl-diphosphatase activity
R7A2020_RS03520	COG0792	nuclease activity
R7A2020_RS03525	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
R7A2020_RS03545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
R7A2020_RS03550	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
R7A2020_RS03560	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
R7A2020_RS03565	COG1420	regulation of RNA biosynthetic process
R7A2020_RS03595	COG4941	Belongs to the sigma-70 factor family
R7A2020_RS03600	COG3795	YCII-related domain
R7A2020_RS03615	COG3685	Protein conserved in bacteria
R7A2020_RS03620	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
R7A2020_RS03660	COG0842	Transport permease protein
R7A2020_RS03665	COG1131	(ABC) transporter
R7A2020_RS03680	COG2954	triphosphatase activity
R7A2020_RS03695	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
R7A2020_RS03715	COG2094	Belongs to the DNA glycosylase MPG family
R7A2020_RS03735	COG0659	secondary active sulfate transmembrane transporter activity
R7A2020_RS03745	COG0671	phosphoesterase, PA-phosphatase related
R7A2020_RS03760	COG2197	response regulator
R7A2020_RS03780	COG3634	alkyl hydroperoxide reductase activity
R7A2020_RS03790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
R7A2020_RS03795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
R7A2020_RS03800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
R7A2020_RS03805	COG1116	anion transmembrane transporter activity
R7A2020_RS03815	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
R7A2020_RS03855	COG3030	protein affecting phage T7 exclusion by the F plasmid
R7A2020_RS03860	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
R7A2020_RS03865	COG0747	negative chemotaxis
R7A2020_RS03885	COG0481	GTPase activity
R7A2020_RS03910	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
R7A2020_RS03930	COG1294	oxidase, subunit
R7A2020_RS03935	COG1271	oxidase subunit
R7A2020_RS03940	COG1131	(ABC) transporter
R7A2020_RS03945	COG0842	Transport permease protein
R7A2020_RS03955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
R7A2020_RS03960	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
R7A2020_RS03965	COG4521	taurine ABC transporter
R7A2020_RS03975	COG1959	2 iron, 2 sulfur cluster binding
R7A2020_RS03990	COG1733	regulation of RNA biosynthetic process
R7A2020_RS03995	COG1335	isochorismatase
R7A2020_RS04015	COG0626	cystathionine gamma-synthase activity
R7A2020_RS04025	COG0006	proline dipeptidase activity
R7A2020_RS04030	COG1335	isochorismatase
R7A2020_RS04040	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
R7A2020_RS04045	COG0237	dephospho-CoA kinase activity
R7A2020_RS04050	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
R7A2020_RS04055	COG0424	maF-like protein
R7A2020_RS04060	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
R7A2020_RS04065	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
R7A2020_RS04075	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
R7A2020_RS04080	COG1331	Highly conserved protein containing a thioredoxin domain
R7A2020_RS04085	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
R7A2020_RS04090	COG0445	tRNA wobble uridine modification
R7A2020_RS04095	COG0357	Ribosomal RNA small subunit methyltransferase G
R7A2020_RS04185	COG3964	amidohydrolase
R7A2020_RS04190	COG2072	flavoprotein involved in K transport
R7A2020_RS04265	COG3118	belongs to the thioredoxin family
R7A2020_RS04270	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
R7A2020_RS04275	COG2835	tetraacyldisaccharide 4'-kinase activity
R7A2020_RS04280	COG0587	DNA-directed DNA polymerase activity
R7A2020_RS04295	COG1280	lysine exporter protein (LysE YggA)
R7A2020_RS04320	COG0745	RESPONSE REGULATOR receiver
R7A2020_RS04325	COG2205	protein histidine kinase activity
R7A2020_RS04350	COG0640	Transcriptional regulator
R7A2020_RS04360	COG0066	3-isopropylmalate dehydratase activity
R7A2020_RS04370	COG0251	oxidation-reduction process
R7A2020_RS04380	COG0473	3-isopropylmalate dehydrogenase activity
R7A2020_RS04405	COG0513	Belongs to the DEAD box helicase family
R7A2020_RS04410	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
R7A2020_RS04425	COG3781	membrane
R7A2020_RS04455	COG0228	four-way junction DNA binding
R7A2020_RS04460	COG1605	Chorismate mutase
R7A2020_RS04460	COG0287	Prephenate dehydrogenase
R7A2020_RS04465	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
R7A2020_RS04470	COG1266	CAAX protease self-immunity
R7A2020_RS04505	COG0137	argininosuccinate synthase activity
R7A2020_RS04510	COG3300	MHYT domain
R7A2020_RS04510	COG5001	Diguanylate cyclase
R7A2020_RS04530	COG0820	rRNA (adenine-C2-)-methyltransferase activity
R7A2020_RS04555	COG3339	Conserved Protein
R7A2020_RS04560	COG2154	pterin-4-alpha-carbinolamine dehydratase
R7A2020_RS04565	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
R7A2020_RS04570	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
R7A2020_RS04580	COG1136	(ABC) transporter
R7A2020_RS04585	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
R7A2020_RS04590	COG0670	Belongs to the BI1 family
R7A2020_RS04620	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
R7A2020_RS04625	COG4133	protoheme IX ABC transporter activity
R7A2020_RS04630	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
R7A2020_RS04640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
R7A2020_RS04660	COG0431	NADPH-dependent FMN reductase
R7A2020_RS04670	COG2917	probably involved in intracellular septation
R7A2020_RS04675	COG0552	protein localization to endoplasmic reticulum
R7A2020_RS04680	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
R7A2020_RS04685	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
R7A2020_RS04710	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
R7A2020_RS04720	COG0039	L-malate dehydrogenase activity
R7A2020_RS04725	COG0045	succinate-CoA ligase (ADP-forming) activity
R7A2020_RS04740	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
R7A2020_RS04745	COG0567	Dehydrogenase, E1 component
R7A2020_RS04750	COG0508	dehydrogenase complex catalyzes the overall conversion of
R7A2020_RS04765	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS04790	COG4974	Belongs to the 'phage' integrase family
R7A2020_RS04795	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
R7A2020_RS04800	COG0336	Belongs to the RNA methyltransferase TrmD family
R7A2020_RS04810	COG0335	large ribosomal subunit rRNA binding
R7A2020_RS04815	COG1764	response to oxidative stress
R7A2020_RS04820	COG1846	Transcriptional regulator
R7A2020_RS04830	COG0765	amino acid transport
R7A2020_RS04840	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
R7A2020_RS04850	COG3706	GGDEF domain
R7A2020_RS04870	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
R7A2020_RS04905	COG3132	Protein of unknown function, DUF480
R7A2020_RS04910	COG1764	response to oxidative stress
R7A2020_RS04920	COG3795	YCII-related domain
R7A2020_RS04930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
R7A2020_RS04935	COG1946	Acyl-CoA thioesterase
R7A2020_RS04940	COG0347	Belongs to the P(II) protein family
R7A2020_RS04945	COG0004	ammonium transporteR
R7A2020_RS04960	COG2261	transglycosylase associated protein
R7A2020_RS04960	COG1674	ftsk spoiiie
R7A2020_RS04965	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
R7A2020_RS04980	COG0745	RESPONSE REGULATOR receiver
R7A2020_RS04995	COG0583	DNA-binding transcription factor activity
R7A2020_RS05020	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
R7A2020_RS05025	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
R7A2020_RS05030	COG0181	hydroxymethylbilane synthase activity
R7A2020_RS05055	COG0519	Catalyzes the synthesis of GMP from XMP
R7A2020_RS05055	COG0518	GMP synthase (glutamine-hydrolyzing) activity
R7A2020_RS05075	COG4957	zinc ion binding
R7A2020_RS05090	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
R7A2020_RS05100	COG1879	ABC-type sugar transport system periplasmic component
R7A2020_RS05105	COG1129	ABC transporter
R7A2020_RS05115	COG1172	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS05120	COG1024	Enoyl-CoA hydratase
R7A2020_RS05120	COG1250	3-hydroxyacyl-CoA dehydrogenase
R7A2020_RS05125	COG1012	belongs to the aldehyde dehydrogenase family
R7A2020_RS05150	COG3842	ATPase activity
R7A2020_RS05155	COG1177	transmembrane transport
R7A2020_RS05175	COG1819	glycosyl
R7A2020_RS05185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
R7A2020_RS05190	COG1414	Transcriptional regulator
R7A2020_RS05195	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
R7A2020_RS05200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
R7A2020_RS05245	COG1335	isochorismatase
R7A2020_RS05255	COG0848	biopolymer transport protein
R7A2020_RS05260	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
R7A2020_RS05295	COG1872	DUF167
R7A2020_RS05300	COG1737	Transcriptional regulator
R7A2020_RS05325	COG0395	ABC-type sugar transport system, permease component
R7A2020_RS05370	COG1704	LemA family
R7A2020_RS05375	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
R7A2020_RS05390	COG1247	-acetyltransferase
R7A2020_RS05395	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
R7A2020_RS05405	COG1309	transcriptional regulator
R7A2020_RS05410	COG2271	Major facilitator Superfamily
R7A2020_RS05435	COG3511	phospholipase C
R7A2020_RS05450	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
R7A2020_RS05460	COG2270	Major facilitator Superfamily
R7A2020_RS05465	COG0138	bifunctional purine biosynthesis protein purh
R7A2020_RS05480	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
R7A2020_RS05480	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
R7A2020_RS05485	COG0501	Belongs to the peptidase M48B family
R7A2020_RS05495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
R7A2020_RS05510	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
R7A2020_RS05520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
R7A2020_RS05525	COG5425	PFAM Usg family protein
R7A2020_RS05530	COG0667	Aldo Keto reductase
R7A2020_RS05540	COG2814	Major facilitator Superfamily
R7A2020_RS05545	COG0583	DNA-binding transcription factor activity
R7A2020_RS05550	COG2321	neutral zinc metallopeptidase
R7A2020_RS05555	COG0667	Aldo Keto reductase
R7A2020_RS05560	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
R7A2020_RS05565	COG0495	leucyl-tRNA aminoacylation
R7A2020_RS05580	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
R7A2020_RS05590	COG1794	racemase activity, acting on amino acids and derivatives
R7A2020_RS05600	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
R7A2020_RS05605	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
R7A2020_RS05610	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
R7A2020_RS05615	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
R7A2020_RS05620	COG0355	proton-transporting ATP synthase activity, rotational mechanism
R7A2020_RS05625	COG0246	Mannitol dehydrogenase
R7A2020_RS05635	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS05655	COG0514	ATP-dependent DNA helicase (RecQ)
R7A2020_RS05670	COG0261	This protein binds to 23S rRNA in the presence of protein L20
R7A2020_RS05670	COG3743	rRNA binding
R7A2020_RS05675	COG0211	Belongs to the bacterial ribosomal protein bL27 family
R7A2020_RS05680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
R7A2020_RS05695	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
R7A2020_RS05700	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
R7A2020_RS05705	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
R7A2020_RS05710	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
R7A2020_RS05720	COG0668	transmembrane transport
R7A2020_RS05725	COG0799	negative regulation of ribosome biogenesis
R7A2020_RS05730	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
R7A2020_RS05740	COG0793	Belongs to the peptidase S41A family
R7A2020_RS05750	COG0494	nUDIX hydrolase
R7A2020_RS05755	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
R7A2020_RS05760	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
R7A2020_RS05770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
R7A2020_RS05805	COG1733	regulation of RNA biosynthetic process
R7A2020_RS05820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
R7A2020_RS05825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
R7A2020_RS05860	COG0683	leucine binding
R7A2020_RS05865	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
R7A2020_RS05870	COG3750	Belongs to the UPF0335 family
R7A2020_RS05890	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
R7A2020_RS05895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
R7A2020_RS05930	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
R7A2020_RS05935	COG1692	metallophosphoesterase
R7A2020_RS05940	COG0861	Integral membrane protein TerC family
R7A2020_RS05960	COG0217	transcriptional regulatory protein
R7A2020_RS05975	COG0702	epimerase
R7A2020_RS05985	COG0254	rRNA binding
R7A2020_RS05990	COG1132	(ABC) transporter
R7A2020_RS06000	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
R7A2020_RS06025	COG1272	protein, Hemolysin III
R7A2020_RS06030	COG0483	inositol monophosphate 1-phosphatase activity
R7A2020_RS06035	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
R7A2020_RS06040	COG0583	DNA-binding transcription factor activity
R7A2020_RS06065	COG1522	sequence-specific DNA binding
R7A2020_RS06070	COG2226	methyltransferase
R7A2020_RS06095	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
R7A2020_RS06100	COG2002	toxin-antitoxin pair type II binding
R7A2020_RS06110	COG0632	four-way junction helicase activity
R7A2020_RS06115	COG2255	four-way junction helicase activity
R7A2020_RS06120	COG1408	metallophosphoesterase
R7A2020_RS06130	COG0824	Thioesterase
R7A2020_RS06140	COG0848	biopolymer transport protein
R7A2020_RS06150	COG0823	Involved in the tonB-independent uptake of proteins
R7A2020_RS06155	COG2885	chlorophyll binding
R7A2020_RS06165	COG0037	tRNA processing
R7A2020_RS06170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
R7A2020_RS06185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
R7A2020_RS06200	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
R7A2020_RS06205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
R7A2020_RS06210	COG0697	spore germination
R7A2020_RS06215	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
R7A2020_RS06240	COG4143	(ABC) transporter
R7A2020_RS06250	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
R7A2020_RS06265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
R7A2020_RS06275	COG1126	abc transporter atp-binding protein
R7A2020_RS06280	COG1329	Transcriptional regulator
R7A2020_RS06285	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
R7A2020_RS06310	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS06315	COG0183	Belongs to the thiolase family
R7A2020_RS06320	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
R7A2020_RS06335	COG0372	Belongs to the citrate synthase family
R7A2020_RS06340	COG0372	Belongs to the citrate synthase family
R7A2020_RS06350	COG1309	transcriptional regulator
R7A2020_RS06355	COG2080	2 iron, 2 sulfur cluster binding
R7A2020_RS06360	COG2010	Cytochrome c
R7A2020_RS06360	COG1529	Aldehyde oxidase and xanthine dehydrogenase
R7A2020_RS06375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
R7A2020_RS06395	COG2223	nitrite transmembrane transporter activity
R7A2020_RS06420	COG0469	pyruvate kinase activity
R7A2020_RS06435	COG0457	Tetratricopeptide repeat
R7A2020_RS06440	COG0257	Belongs to the bacterial ribosomal protein bL36 family
R7A2020_RS06445	COG3755	Protein conserved in bacteria
R7A2020_RS06450	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
R7A2020_RS06475	COG1921	L-seryl-tRNASec selenium transferase activity
R7A2020_RS06490	COG0765	amino acid transport
R7A2020_RS06495	COG0765	amino acid transport
R7A2020_RS06520	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
R7A2020_RS06525	COG1196	nuclear chromosome segregation
R7A2020_RS06525	COG0741	lytic transglycosylase activity
R7A2020_RS06525	COG0739	heme binding
R7A2020_RS06550	COG2226	methyltransferase
R7A2020_RS06555	COG2205	protein histidine kinase activity
R7A2020_RS06555	COG5002	protein histidine kinase activity
R7A2020_RS06555	COG0784	Response regulator, receiver
R7A2020_RS06560	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS06565	COG0142	geranyltranstransferase activity
R7A2020_RS06570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
R7A2020_RS06575	COG0333	Belongs to the bacterial ribosomal protein bL32 family
R7A2020_RS06620	COG0640	Transcriptional regulator
R7A2020_RS06670	COG0346	lactoylglutathione lyase activity
R7A2020_RS06690	COG3588	fructose-bisphosphate aldolase
R7A2020_RS06695	COG0126	phosphoglycerate kinase activity
R7A2020_RS06725	COG0450	alkyl hydroperoxide reductase
R7A2020_RS06730	COG3453	Protein conserved in bacteria
R7A2020_RS06730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
R7A2020_RS06735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
R7A2020_RS06740	COG0564	pseudouridine synthase activity
R7A2020_RS06750	COG0346	lactoylglutathione lyase activity
R7A2020_RS06775	COG0625	glutathione transferase activity
R7A2020_RS06800	COG2205	protein histidine kinase activity
R7A2020_RS06800	COG5002	protein histidine kinase activity
R7A2020_RS06800	COG0784	Response regulator, receiver
R7A2020_RS06805	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
R7A2020_RS06810	COG0573	inorganic phosphate transmembrane transporter activity
R7A2020_RS06815	COG0581	inorganic phosphate transmembrane transporter activity
R7A2020_RS06820	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
R7A2020_RS06825	COG0704	Plays a role in the regulation of phosphate uptake
R7A2020_RS06830	COG0745	RESPONSE REGULATOR receiver
R7A2020_RS06835	COG1940	carbohydrate kinase activity
R7A2020_RS06840	COG4213	ABC transporter substrate-binding protein
R7A2020_RS06845	COG4214	carbohydrate transport
R7A2020_RS06850	COG1129	ABC transporter
R7A2020_RS06885	COG0784	Response regulator, receiver
R7A2020_RS06905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
R7A2020_RS06920	COG3920	Histidine kinase
R7A2020_RS06930	COG1597	lipid kinase activity
R7A2020_RS06945	COG0346	lactoylglutathione lyase activity
R7A2020_RS06950	COG0400	carboxylic ester hydrolase activity
R7A2020_RS06970	COG0404	The glycine cleavage system catalyzes the degradation of glycine
R7A2020_RS06985	COG2226	methyltransferase
R7A2020_RS07005	COG1231	oxidoreductase activity
R7A2020_RS07010	COG3842	ATPase activity
R7A2020_RS07020	COG1176	ABC-type spermidine putrescine transport system, permease component I
R7A2020_RS07030	COG4638	Rieske (2fe-2S)
R7A2020_RS07040	COG2203	Gaf domain
R7A2020_RS07040	COG2200	EAL domain
R7A2020_RS07040	COG2199	diguanylate cyclase activity
R7A2020_RS07045	COG0745	RESPONSE REGULATOR receiver
R7A2020_RS07050	COG0745	RESPONSE REGULATOR receiver
R7A2020_RS07070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
R7A2020_RS07085	COG3842	ATPase activity
R7A2020_RS07110	COG1653	transport
R7A2020_RS07115	COG1846	Transcriptional regulator
R7A2020_RS07115	COG1940	carbohydrate kinase activity
R7A2020_RS07120	COG0306	phosphate transporter
R7A2020_RS07135	COG4689	acetoacetate decarboxylase
R7A2020_RS07140	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS07145	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
R7A2020_RS07155	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
R7A2020_RS07160	COG0508	dehydrogenase complex catalyzes the overall conversion of
R7A2020_RS07160	COG0022	dehydrogenase e1 component
R7A2020_RS07165	COG0508	dehydrogenase complex catalyzes the overall conversion of
R7A2020_RS07170	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
R7A2020_RS07180	COG3842	ATPase activity
R7A2020_RS07200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
R7A2020_RS07220	COG3732	PTS system glucitol sorbitol-specific
R7A2020_RS07230	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
R7A2020_RS07245	COG2390	Transcriptional regulator
R7A2020_RS07255	COG1070	Carbohydrate kinase
R7A2020_RS07280	COG1172	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS07290	COG1082	Xylose isomerase domain protein TIM barrel
R7A2020_RS07315	COG1175	transmembrane transport
R7A2020_RS07320	COG0395	ABC-type sugar transport system, permease component
R7A2020_RS07325	COG3842	ATPase activity
R7A2020_RS07330	COG2132	Multicopper oxidase
R7A2020_RS07365	COG1473	amidohydrolase
R7A2020_RS07375	COG0523	cobalamin synthesis protein
R7A2020_RS07380	COG0425	Belongs to the sulfur carrier protein TusA family
R7A2020_RS07390	COG0825	malonyl-CoA metabolic process
R7A2020_RS07395	COG4974	Belongs to the 'phage' integrase family
R7A2020_RS07405	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
R7A2020_RS07410	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
R7A2020_RS07415	COG4536	flavin adenine dinucleotide binding
R7A2020_RS07425	COG0028	Belongs to the TPP enzyme family
R7A2020_RS07485	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
R7A2020_RS07490	COG0227	Belongs to the bacterial ribosomal protein bL28 family
R7A2020_RS07515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
R7A2020_RS07520	COG2226	methyltransferase
R7A2020_RS07525	COG4178	(ABC) transporter
R7A2020_RS07540	COG2813	Specifically methylates the guanine in position
R7A2020_RS07540	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
R7A2020_RS07545	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
R7A2020_RS07550	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
R7A2020_RS07555	COG0287	Prephenate dehydrogenase
R7A2020_RS07560	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
R7A2020_RS07560	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
R7A2020_RS07575	COG0667	Aldo Keto reductase
R7A2020_RS07615	COG2884	Cell division ATP-binding protein ftsE
R7A2020_RS07640	COG0583	DNA-binding transcription factor activity
R7A2020_RS07660	COG0640	Transcriptional regulator
R7A2020_RS07665	COG0019	diaminopimelate decarboxylase activity
R7A2020_RS07675	COG0165	Argininosuccinate lyase
R7A2020_RS07680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
R7A2020_RS07685	COG5001	Diguanylate cyclase
R7A2020_RS07685	COG3300	MHYT domain
R7A2020_RS07695	COG1175	transmembrane transport
R7A2020_RS07705	COG3842	ATPase activity
R7A2020_RS07710	COG3842	ATPase activity
R7A2020_RS07735	COG5002	protein histidine kinase activity
R7A2020_RS07735	COG3447	MASE1 domain protein
R7A2020_RS07735	COG5001	Diguanylate cyclase
R7A2020_RS07740	COG1250	3-hydroxyacyl-CoA dehydrogenase
R7A2020_RS07745	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
R7A2020_RS07750	COG2086	electron transfer activity
R7A2020_RS07770	COG0300	oxidoreductase activity
R7A2020_RS07780	COG0697	spore germination
R7A2020_RS07785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
R7A2020_RS07835	COG0653	protein targeting
R7A2020_RS07840	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
R7A2020_RS07850	COG2814	Major facilitator Superfamily
R7A2020_RS07860	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
R7A2020_RS07870	COG0494	nUDIX hydrolase
R7A2020_RS07890	COG1040	competence protein
R7A2020_RS07900	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
R7A2020_RS07910	COG1846	Transcriptional regulator
R7A2020_RS07925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
R7A2020_RS07930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
R7A2020_RS07935	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
R7A2020_RS07955	COG0527	aspartate kinase activity
R7A2020_RS07965	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
R7A2020_RS07970	COG2890	protein-(glutamine-N5) methyltransferase activity
R7A2020_RS07980	COG0542	response to heat
R7A2020_RS07990	COG1376	ErfK ybiS ycfS ynhG family protein
R7A2020_RS07995	COG3548	integral membrane protein
R7A2020_RS08000	COG0477	Major facilitator Superfamily
R7A2020_RS08005	COG0739	heme binding
R7A2020_RS08045	COG3609	addiction module antidote protein, CC2985 family
R7A2020_RS08095	COG2910	NAD(P)H-binding
R7A2020_RS08110	COG1940	carbohydrate kinase activity
R7A2020_RS08120	COG2390	Transcriptional regulator
R7A2020_RS08125	COG1879	ABC-type sugar transport system periplasmic component
R7A2020_RS08135	COG1129	ABC transporter
R7A2020_RS08155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
R7A2020_RS08160	COG0601	transmembrane transport
R7A2020_RS08165	COG0747	negative chemotaxis
R7A2020_RS08185	COG5564	TIM-barrel signal transduction protein
R7A2020_RS08190	COG5441	Belongs to the UPF0261 family
R7A2020_RS08200	COG3842	ATPase activity
R7A2020_RS08215	COG0395	ABC-type sugar transport system, permease component
R7A2020_RS08220	COG3842	ATPase activity
R7A2020_RS08230	COG3842	ATPase activity
R7A2020_RS08240	COG2207	Transcriptional regulator
R7A2020_RS08270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
R7A2020_RS08280	COG4948	Mandelate Racemase Muconate Lactonizing
R7A2020_RS08295	COG0673	inositol 2-dehydrogenase activity
R7A2020_RS08305	COG3639	organic phosphonate transmembrane transporter activity
R7A2020_RS08310	COG3639	organic phosphonate transmembrane transporter activity
R7A2020_RS08320	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
R7A2020_RS08335	COG4778	phosphonate C-P lyase system protein PhnL
R7A2020_RS08340	COG4107	phosphonate C-P lyase system protein PhnK
R7A2020_RS08345	COG3627	carbon phosphorus lyase activity
R7A2020_RS08350	COG0346	lactoylglutathione lyase activity
R7A2020_RS08355	COG3626	phosphonate metabolism
R7A2020_RS08360	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
R7A2020_RS08365	COG3624	Phosphonate C-P lyase system protein PhnG
R7A2020_RS08370	COG2188	Transcriptional regulator
R7A2020_RS08375	COG1063	alcohol dehydrogenase
R7A2020_RS08380	COG1172	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS08385	COG1129	ABC transporter
R7A2020_RS08390	COG1879	ABC-type sugar transport system periplasmic component
R7A2020_RS08400	COG2721	sulfolactate sulfo-lyase activity
R7A2020_RS08405	COG1802	Transcriptional regulator
R7A2020_RS08430	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
R7A2020_RS08445	COG1175	transmembrane transport
R7A2020_RS08450	COG0395	ABC-type sugar transport system, permease component
R7A2020_RS08455	COG3842	ATPase activity
R7A2020_RS08465	COG0673	inositol 2-dehydrogenase activity
R7A2020_RS08470	COG0667	Aldo Keto reductase
R7A2020_RS08495	COG2319	Wd-40 repeat
R7A2020_RS08515	COG0735	belongs to the Fur family
R7A2020_RS08520	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
R7A2020_RS08520	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
R7A2020_RS08525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
R7A2020_RS08565	COG0668	transmembrane transport
R7A2020_RS08575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
R7A2020_RS08580	COG1442	glycosyl transferase family 8
R7A2020_RS08580	COG1216	Glycosyl transferase, family 2
R7A2020_RS08585	COG0726	polysaccharide deacetylase
R7A2020_RS08610	COG1247	-acetyltransferase
R7A2020_RS08630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
R7A2020_RS08635	COG0601	transmembrane transport
R7A2020_RS08685	COG1132	(ABC) transporter
R7A2020_RS08695	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
R7A2020_RS08720	COG3047	cAMP biosynthetic process
R7A2020_RS08720	COG2885	chlorophyll binding
R7A2020_RS08735	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
R7A2020_RS08750	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS08760	COG2207	Transcriptional regulator
R7A2020_RS08765	COG4651	solute:proton antiporter activity
R7A2020_RS08765	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
R7A2020_RS08780	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
R7A2020_RS08780	COG1648	precorrin-2 dehydrogenase activity
R7A2020_RS08790	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
R7A2020_RS08795	COG0175	sulfate reduction
R7A2020_RS08815	COG3239	Fatty acid desaturase
R7A2020_RS08825	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
R7A2020_RS08830	COG2860	membrane
R7A2020_RS08850	COG0604	alcohol dehydrogenase
R7A2020_RS08855	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
R7A2020_RS08860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
R7A2020_RS08865	COG0116	Belongs to the methyltransferase superfamily
R7A2020_RS08865	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
R7A2020_RS08870	COG2378	regulation of single-species biofilm formation
R7A2020_RS08885	COG2423	ornithine cyclodeaminase activity
R7A2020_RS08895	COG0776	regulation of translation
R7A2020_RS08900	COG0616	signal peptide processing
R7A2020_RS08910	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
R7A2020_RS08915	COG1137	ATPase activity
R7A2020_RS08920	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
R7A2020_RS08925	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
R7A2020_RS08930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
R7A2020_RS08945	COG1957	nucleoside hydrolase
R7A2020_RS08950	COG1280	lysine exporter protein (LysE YggA)
R7A2020_RS08955	COG0154	amidase activity
R7A2020_RS08960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
R7A2020_RS08990	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
R7A2020_RS09020	COG5001	Diguanylate cyclase
R7A2020_RS09020	COG5002	protein histidine kinase activity
R7A2020_RS09040	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
R7A2020_RS09045	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
R7A2020_RS09050	COG2226	methyltransferase
R7A2020_RS09055	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
R7A2020_RS09060	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
R7A2020_RS09070	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
R7A2020_RS09100	COG2900	Belongs to the SlyX family
R7A2020_RS09170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
R7A2020_RS09230	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
R7A2020_RS09240	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
R7A2020_RS09245	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
R7A2020_RS09250	COG2205	protein histidine kinase activity
R7A2020_RS09260	COG2814	Major facilitator Superfamily
R7A2020_RS09280	COG0828	Belongs to the bacterial ribosomal protein bS21 family
R7A2020_RS09300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
R7A2020_RS09315	COG0404	The glycine cleavage system catalyzes the degradation of glycine
R7A2020_RS09315	COG0446	pyridine nucleotide-disulphide oxidoreductase
R7A2020_RS09335	COG0673	inositol 2-dehydrogenase activity
R7A2020_RS09350	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS09385	COG0463	Glycosyl transferase, family 2
R7A2020_RS09405	COG0583	DNA-binding transcription factor activity
R7A2020_RS09425	COG0531	amino acid
R7A2020_RS09460	COG3842	ATPase activity
R7A2020_RS09480	COG2814	Major facilitator Superfamily
R7A2020_RS09495	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS09505	COG3842	ATPase activity
R7A2020_RS09510	COG0395	ABC-type sugar transport system, permease component
R7A2020_RS09515	COG1175	transmembrane transport
R7A2020_RS09520	COG1653	transport
R7A2020_RS09525	COG1012	belongs to the aldehyde dehydrogenase family
R7A2020_RS09530	COG1024	Enoyl-CoA hydratase
R7A2020_RS09545	COG1609	Transcriptional regulator
R7A2020_RS09575	COG0483	inositol monophosphate 1-phosphatase activity
R7A2020_RS09600	COG0071	Belongs to the small heat shock protein (HSP20) family
R7A2020_RS09610	COG0069	glutamate synthase activity
R7A2020_RS09610	COG0067	glutamate synthase
R7A2020_RS09610	COG0070	glutamate synthase
R7A2020_RS09625	COG2951	lytic endotransglycosylase activity
R7A2020_RS09630	COG1210	Utp--glucose-1-phosphate uridylyltransferase
R7A2020_RS09650	COG0330	HflC and HflK could
R7A2020_RS09655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
R7A2020_RS09655	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
R7A2020_RS09660	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
R7A2020_RS09665	COG0737	Belongs to the 5'-nucleotidase family
R7A2020_RS09675	COG5310	Homospermidine synthase
R7A2020_RS09680	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS09685	COG0583	DNA-binding transcription factor activity
R7A2020_RS09710	COG0261	This protein binds to 23S rRNA in the presence of protein L20
R7A2020_RS09710	COG3743	rRNA binding
R7A2020_RS09720	COG2204	response regulator
R7A2020_RS09725	COG3108	Peptidase M15
R7A2020_RS09730	COG2207	Transcriptional regulator
R7A2020_RS09760	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS09765	COG3795	YCII-related domain
R7A2020_RS09790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
R7A2020_RS09805	COG0583	DNA-binding transcription factor activity
R7A2020_RS09810	COG0154	amidase activity
R7A2020_RS09870	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
R7A2020_RS09905	COG1176	ABC-type spermidine putrescine transport system, permease component I
R7A2020_RS09910	COG1177	transmembrane transport
R7A2020_RS09915	COG3842	ATPase activity
R7A2020_RS09930	COG2814	Major facilitator Superfamily
R7A2020_RS09940	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
R7A2020_RS09945	COG5443	negative regulation of bacterial-type flagellum assembly
R7A2020_RS09965	COG1749	Flagellar hook protein flgE
R7A2020_RS10005	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
R7A2020_RS10010	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
R7A2020_RS10015	COG1338	Plays a role in the flagellum-specific transport system
R7A2020_RS10025	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
R7A2020_RS10035	COG1706	bacterial-type flagellum-dependent cell motility
R7A2020_RS10040	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
R7A2020_RS10045	COG4786	Flagellar basal body rod
R7A2020_RS10050	COG1677	Flagellar hook-basal body complex protein FliE
R7A2020_RS10055	COG1558	bacterial-type flagellum-dependent cell motility
R7A2020_RS10060	COG1815	bacterial-type flagellum-dependent cell motility
R7A2020_RS10070	COG1157	protein secretion by the type III secretion system
R7A2020_RS10075	COG4786	Flagellar basal body rod
R7A2020_RS10085	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
R7A2020_RS10090	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
R7A2020_RS10095	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
R7A2020_RS10100	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
R7A2020_RS10105	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
R7A2020_RS10120	COG2771	luxR family
R7A2020_RS10140	COG1574	metal-dependent hydrolase with the TIM-barrel fold
R7A2020_RS10145	COG3842	ATPase activity
R7A2020_RS10150	COG1176	ABC-type spermidine putrescine transport system, permease component I
R7A2020_RS10155	COG1177	transmembrane transport
R7A2020_RS10175	COG2183	response to ionizing radiation
R7A2020_RS10195	COG1960	acyl-CoA dehydrogenase activity
R7A2020_RS10210	COG1305	Transglutaminase-like
R7A2020_RS10225	COG3795	YCII-related domain
R7A2020_RS10230	COG4941	Belongs to the sigma-70 factor family
R7A2020_RS10235	COG1012	belongs to the aldehyde dehydrogenase family
R7A2020_RS10250	COG0243	molybdopterin cofactor binding
R7A2020_RS10260	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
R7A2020_RS10265	COG1116	anion transmembrane transporter activity
R7A2020_RS10270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
R7A2020_RS10275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
R7A2020_RS10280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
R7A2020_RS10300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
R7A2020_RS10315	COG2207	Transcriptional regulator
R7A2020_RS10380	COG4249	Peptidase C14 caspase catalytic subunit p20
R7A2020_RS10380	COG2319	Wd-40 repeat
R7A2020_RS10400	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS10405	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
R7A2020_RS10410	COG1309	transcriptional regulator
R7A2020_RS10425	COG0673	inositol 2-dehydrogenase activity
R7A2020_RS10430	COG0482	sulfurtransferase activity
R7A2020_RS10445	COG1733	regulation of RNA biosynthetic process
R7A2020_RS10460	COG2201	protein-glutamate methylesterase activity
R7A2020_RS10505	COG0435	Glutathione S-transferase
R7A2020_RS10530	COG0508	dehydrogenase complex catalyzes the overall conversion of
R7A2020_RS10530	COG0596	Alpha beta hydrolase
R7A2020_RS10540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
R7A2020_RS10565	COG0583	DNA-binding transcription factor activity
R7A2020_RS10570	COG3180	Ammonia monooxygenase
R7A2020_RS10580	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS10595	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
R7A2020_RS10600	COG0512	Glutamine amidotransferase of anthranilate synthase
R7A2020_RS10600	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
R7A2020_RS10605	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
R7A2020_RS10615	COG2814	Major facilitator Superfamily
R7A2020_RS10620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
R7A2020_RS10640	COG1335	isochorismatase
R7A2020_RS10645	COG2759	Belongs to the formate--tetrahydrofolate ligase family
R7A2020_RS10680	COG0583	DNA-binding transcription factor activity
R7A2020_RS10685	COG0697	spore germination
R7A2020_RS10690	COG1435	thymidine kinase activity
R7A2020_RS10700	COG4176	ABC-type proline glycine betaine transport system permease component
R7A2020_RS10715	COG0745	RESPONSE REGULATOR receiver
R7A2020_RS10735	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
R7A2020_RS10755	COG0714	Associated with various cellular activities
R7A2020_RS10765	COG0494	nUDIX hydrolase
R7A2020_RS10770	COG0617	tRNA 3'-terminal CCA addition
R7A2020_RS10790	COG0408	coproporphyrinogen oxidase activity
R7A2020_RS10800	COG0789	Transcriptional regulator
R7A2020_RS10805	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
R7A2020_RS10815	COG1132	(ABC) transporter
R7A2020_RS10820	COG1132	(ABC) transporter
R7A2020_RS10855	COG2857	Cytochrome c1
R7A2020_RS10855	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
R7A2020_RS10875	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
R7A2020_RS10900	COG0012	GTP binding
R7A2020_RS10905	COG0193	aminoacyl-tRNA hydrolase activity
R7A2020_RS10910	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
R7A2020_RS10920	COG1846	Transcriptional regulator
R7A2020_RS10930	COG2223	nitrite transmembrane transporter activity
R7A2020_RS10935	COG2207	Transcriptional regulator
R7A2020_RS10945	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
R7A2020_RS10970	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
R7A2020_RS10990	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
R7A2020_RS11005	COG2205	protein histidine kinase activity
R7A2020_RS11010	COG0745	RESPONSE REGULATOR receiver
R7A2020_RS11015	COG1846	Transcriptional regulator
R7A2020_RS11020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
R7A2020_RS11030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
R7A2020_RS11040	COG1278	Cold shock
R7A2020_RS11045	COG1278	Cold shock
R7A2020_RS11080	COG1278	Cold shock
R7A2020_RS11090	COG0457	Tetratricopeptide repeat
R7A2020_RS11100	COG5507	3-demethylubiquinone-9 3-methyltransferase
R7A2020_RS11125	COG0488	(ABC) transporter
R7A2020_RS11140	COG0556	nucleotide-excision repair
R7A2020_RS11150	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
R7A2020_RS11195	COG0277	FAD linked oxidase domain protein
R7A2020_RS11210	COG0596	Alpha beta hydrolase
R7A2020_RS11225	COG1597	lipid kinase activity
R7A2020_RS11235	COG4948	Mandelate Racemase Muconate Lactonizing
R7A2020_RS11245	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
R7A2020_RS11280	COG1733	regulation of RNA biosynthetic process
R7A2020_RS11305	COG4941	Belongs to the sigma-70 factor family
R7A2020_RS11310	COG3795	YCII-related domain
R7A2020_RS11320	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
R7A2020_RS11320	COG2273	Hydrolase Family 16
R7A2020_RS11335	COG1253	flavin adenine dinucleotide binding
R7A2020_RS11340	COG0583	DNA-binding transcription factor activity
R7A2020_RS11345	COG0604	alcohol dehydrogenase
R7A2020_RS11345	COG3321	synthase
R7A2020_RS11345	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS11375	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
R7A2020_RS11380	COG0859	PFAM glycosyl transferase family 9
R7A2020_RS11390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
R7A2020_RS11400	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
R7A2020_RS11400	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
R7A2020_RS11405	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
R7A2020_RS11410	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
R7A2020_RS11415	COG0463	Glycosyl transferase, family 2
R7A2020_RS11420	COG1522	sequence-specific DNA binding
R7A2020_RS11425	COG0492	ferredoxin-NADP+ reductase activity
R7A2020_RS11430	COG0583	DNA-binding transcription factor activity
R7A2020_RS11440	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
R7A2020_RS11460	COG0477	Major facilitator Superfamily
R7A2020_RS11465	COG0436	Aminotransferase
R7A2020_RS11475	COG3300	MHYT domain
R7A2020_RS11475	COG5001	Diguanylate cyclase
R7A2020_RS11480	COG0625	glutathione transferase activity
R7A2020_RS11495	COG0583	DNA-binding transcription factor activity
R7A2020_RS11505	COG1278	Cold shock
R7A2020_RS11515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
R7A2020_RS11550	COG0251	oxidation-reduction process
R7A2020_RS11565	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
R7A2020_RS11590	COG2814	Major facilitator Superfamily
R7A2020_RS11600	COG4221	oxidoreductase activity
R7A2020_RS11610	COG0583	DNA-binding transcription factor activity
R7A2020_RS11620	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
R7A2020_RS11625	COG1914	H( )-stimulated, divalent metal cation uptake system
R7A2020_RS11630	COG1321	iron dependent repressor
R7A2020_RS11650	COG2321	neutral zinc metallopeptidase
R7A2020_RS11660	COG4989	oxidoreductase activity
R7A2020_RS11665	COG0505	Belongs to the CarA family
R7A2020_RS11675	COG0583	DNA-binding transcription factor activity
R7A2020_RS11680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
R7A2020_RS11700	COG0789	Transcriptional regulator
R7A2020_RS11710	COG0300	oxidoreductase activity
R7A2020_RS11715	COG0583	DNA-binding transcription factor activity
R7A2020_RS11720	COG2814	Major facilitator Superfamily
R7A2020_RS11740	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
R7A2020_RS11765	COG1695	Transcriptional regulator
R7A2020_RS11790	COG3510	cephalosporin hydroxylase
R7A2020_RS11845	COG1172	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS11860	COG0673	inositol 2-dehydrogenase activity
R7A2020_RS11875	COG0450	alkyl hydroperoxide reductase
R7A2020_RS11880	COG1252	NADH dehydrogenase
R7A2020_RS11885	COG2223	nitrite transmembrane transporter activity
R7A2020_RS11890	COG1522	sequence-specific DNA binding
R7A2020_RS11905	COG3668	Plasmid stabilization system
R7A2020_RS11910	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
R7A2020_RS11915	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
R7A2020_RS11940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
R7A2020_RS11945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
R7A2020_RS11950	COG2197	response regulator
R7A2020_RS11955	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS11965	COG2983	Belongs to the UPF0260 family
R7A2020_RS11975	COG2968	Membrane
R7A2020_RS12000	COG0459	protein refolding
R7A2020_RS12005	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
R7A2020_RS12030	COG0071	Belongs to the small heat shock protein (HSP20) family
R7A2020_RS12035	COG0071	Belongs to the small heat shock protein (HSP20) family
R7A2020_RS12075	COG1295	ribonuclease BN
R7A2020_RS12115	COG0739	heme binding
R7A2020_RS12140	COG1360	Flagellar Motor Protein
R7A2020_RS12150	COG3501	Rhs element vgr protein
R7A2020_RS12195	COG2885	chlorophyll binding
R7A2020_RS12265	COG4948	Mandelate Racemase Muconate Lactonizing
R7A2020_RS12270	COG3842	ATPase activity
R7A2020_RS12285	COG1653	transport
R7A2020_RS12295	COG4948	Mandelate Racemase Muconate Lactonizing
R7A2020_RS12300	COG4948	Mandelate Racemase Muconate Lactonizing
R7A2020_RS12310	COG4948	Mandelate Racemase Muconate Lactonizing
R7A2020_RS12315	COG1012	belongs to the aldehyde dehydrogenase family
R7A2020_RS12325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
R7A2020_RS12330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
R7A2020_RS12340	COG0110	maltose O-acetyltransferase activity
R7A2020_RS12355	COG3454	Phosphonate metabolism
R7A2020_RS12370	COG4191	Histidine kinase
R7A2020_RS12370	COG0784	Response regulator, receiver
R7A2020_RS12385	COG3300	MHYT domain
R7A2020_RS12385	COG5001	Diguanylate cyclase
R7A2020_RS12390	COG1473	amidohydrolase
R7A2020_RS12420	COG2080	2 iron, 2 sulfur cluster binding
R7A2020_RS12420	COG1529	Aldehyde oxidase and xanthine dehydrogenase
R7A2020_RS12430	COG0210	DNA helicase
R7A2020_RS12435	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
R7A2020_RS12480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
R7A2020_RS12485	COG4221	oxidoreductase activity
R7A2020_RS12490	COG1595	DNA-templated transcription, initiation
R7A2020_RS12500	COG0475	glutathione-regulated potassium exporter activity
R7A2020_RS12515	COG2814	Major facilitator Superfamily
R7A2020_RS12520	COG0583	DNA-binding transcription factor activity
R7A2020_RS12530	COG0071	Belongs to the small heat shock protein (HSP20) family
R7A2020_RS12550	COG0346	lactoylglutathione lyase activity
R7A2020_RS12580	COG0395	ABC-type sugar transport system, permease component
R7A2020_RS12585	COG1175	transmembrane transport
R7A2020_RS12595	COG1609	Transcriptional regulator
R7A2020_RS12630	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
R7A2020_RS12635	COG0459	protein refolding
R7A2020_RS12650	COG1956	GAF domain-containing protein
R7A2020_RS12655	COG2855	membrane
R7A2020_RS12665	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
R7A2020_RS12700	COG1902	pentaerythritol trinitrate reductase activity
R7A2020_RS12725	COG0765	amino acid transport
R7A2020_RS12750	COG2207	Transcriptional regulator
R7A2020_RS12760	COG0583	DNA-binding transcription factor activity
R7A2020_RS12775	COG0110	maltose O-acetyltransferase activity
R7A2020_RS12790	COG0406	alpha-ribazole phosphatase activity
R7A2020_RS12810	COG0583	DNA-binding transcription factor activity
R7A2020_RS12815	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS12855	COG0667	Aldo Keto reductase
R7A2020_RS12860	COG0583	DNA-binding transcription factor activity
R7A2020_RS12885	COG0492	ferredoxin-NADP+ reductase activity
R7A2020_RS12895	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
R7A2020_RS12900	COG0730	response to heat
R7A2020_RS12905	COG2391	methyltransferase activity
R7A2020_RS12920	COG3453	Protein conserved in bacteria
R7A2020_RS12920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
R7A2020_RS12960	COG1129	ABC transporter
R7A2020_RS12965	COG1172	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS13025	COG3756	Protein conserved in bacteria
R7A2020_RS13045	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
R7A2020_RS13045	COG2755	lipolytic protein G-D-S-L family
R7A2020_RS13080	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS13085	COG0604	alcohol dehydrogenase
R7A2020_RS13150	COG0753	catalase activity
R7A2020_RS13165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
R7A2020_RS13170	COG1609	Transcriptional regulator
R7A2020_RS13185	COG0489	protein tyrosine kinase activity
R7A2020_RS13185	COG3206	protein involved in exopolysaccharide biosynthesis
R7A2020_RS13205	COG0297	glycogen (starch) synthase activity
R7A2020_RS13245	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
R7A2020_RS13290	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
R7A2020_RS13320	COG0625	glutathione transferase activity
R7A2020_RS13325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
R7A2020_RS13330	COG0583	DNA-binding transcription factor activity
R7A2020_RS13360	COG0625	glutathione transferase activity
R7A2020_RS13365	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS13380	COG0488	(ABC) transporter
R7A2020_RS13410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
R7A2020_RS13425	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
R7A2020_RS13430	COG3842	ATPase activity
R7A2020_RS13440	COG1177	transmembrane transport
R7A2020_RS13445	COG4149	molybdate abc transporter
R7A2020_RS13450	COG0326	Molecular chaperone. Has ATPase activity
R7A2020_RS13480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
R7A2020_RS13485	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
R7A2020_RS13505	COG1376	ErfK ybiS ycfS ynhG family protein
R7A2020_RS13530	COG0583	DNA-binding transcription factor activity
R7A2020_RS13585	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS13610	COG0583	DNA-binding transcription factor activity
R7A2020_RS13685	COG1309	transcriptional regulator
R7A2020_RS13690	COG0667	Aldo Keto reductase
R7A2020_RS13695	COG0850	regulation of cytokinetic process
R7A2020_RS13700	COG2894	cell division
R7A2020_RS13705	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
R7A2020_RS13710	COG1132	(ABC) transporter
R7A2020_RS13715	COG0463	Glycosyl transferase, family 2
R7A2020_RS13720	COG1216	Glycosyl transferase, family 2
R7A2020_RS13725	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
R7A2020_RS13725	COG2755	lipolytic protein G-D-S-L family
R7A2020_RS13730	COG2197	response regulator
R7A2020_RS13740	COG5006	permease, DMT superfamily
R7A2020_RS13765	COG1030	water channel activity
R7A2020_RS13770	COG0330	HflC and HflK could
R7A2020_RS13780	COG0583	DNA-binding transcription factor activity
R7A2020_RS13790	COG1529	Aldehyde oxidase and xanthine dehydrogenase
R7A2020_RS13795	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
R7A2020_RS13800	COG2080	2 iron, 2 sulfur cluster binding
R7A2020_RS13805	COG1309	transcriptional regulator
R7A2020_RS13815	COG1349	DNA-binding transcription factor activity
R7A2020_RS13820	COG1129	ABC transporter
R7A2020_RS13825	COG1172	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS13845	COG1131	(ABC) transporter
R7A2020_RS13850	COG0604	alcohol dehydrogenase
R7A2020_RS13875	COG0656	L-ascorbic acid biosynthetic process
R7A2020_RS13880	COG2852	Protein conserved in bacteria
R7A2020_RS13900	COG2226	methyltransferase
R7A2020_RS13910	COG4221	oxidoreductase activity
R7A2020_RS13935	COG1172	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS13940	COG1129	ABC transporter
R7A2020_RS13950	COG1082	Xylose isomerase domain protein TIM barrel
R7A2020_RS13955	COG0246	Mannitol dehydrogenase
R7A2020_RS13960	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS13970	COG0673	inositol 2-dehydrogenase activity
R7A2020_RS13985	COG1162	GTPase activity
R7A2020_RS13990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
R7A2020_RS14025	COG2267	carboxylic ester hydrolase activity
R7A2020_RS14040	COG2169	Transcriptional regulator
R7A2020_RS14040	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
R7A2020_RS14050	COG2169	Transcriptional regulator
R7A2020_RS14050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
R7A2020_RS14060	COG1733	regulation of RNA biosynthetic process
R7A2020_RS14085	COG5002	protein histidine kinase activity
R7A2020_RS14085	COG5001	Diguanylate cyclase
R7A2020_RS14105	COG0318	PFAM AMP-dependent synthetase and ligase
R7A2020_RS14110	COG1024	Enoyl-CoA hydratase
R7A2020_RS14130	COG2423	ornithine cyclodeaminase activity
R7A2020_RS14140	COG0583	DNA-binding transcription factor activity
R7A2020_RS14145	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS14150	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
R7A2020_RS14155	COG5001	Diguanylate cyclase
R7A2020_RS14165	COG1522	sequence-specific DNA binding
R7A2020_RS14200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
R7A2020_RS14220	COG1181	Belongs to the D-alanine--D-alanine ligase family
R7A2020_RS14225	COG0628	permease
R7A2020_RS14255	COG0667	Aldo Keto reductase
R7A2020_RS14270	COG3852	Histidine kinase
R7A2020_RS14310	COG0596	Alpha beta hydrolase
R7A2020_RS14405	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
R7A2020_RS14415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
R7A2020_RS14420	COG1116	anion transmembrane transporter activity
R7A2020_RS14455	COG3920	Histidine kinase
R7A2020_RS14475	COG1397	ADP-ribosylglycohydrolase
R7A2020_RS14485	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
R7A2020_RS14495	COG1177	transmembrane transport
R7A2020_RS14500	COG3842	ATPase activity
R7A2020_RS14535	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
R7A2020_RS14540	COG2986	histidine ammonia-lyase
R7A2020_RS14550	COG0477	Major facilitator Superfamily
R7A2020_RS14555	COG1172	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS14575	COG1129	ABC transporter
R7A2020_RS14595	COG0542	response to heat
R7A2020_RS14605	COG1529	Aldehyde oxidase and xanthine dehydrogenase
R7A2020_RS14625	COG2169	Transcriptional regulator
R7A2020_RS14625	COG1917	Cupin 2, conserved barrel domain protein
R7A2020_RS14630	COG1172	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS14635	COG1129	ABC transporter
R7A2020_RS14645	COG2186	Transcriptional regulator
R7A2020_RS14655	COG1086	Polysaccharide biosynthesis protein
R7A2020_RS14670	COG2271	Major facilitator Superfamily
R7A2020_RS14675	COG1609	Transcriptional regulator
R7A2020_RS14680	COG1879	ABC-type sugar transport system periplasmic component
R7A2020_RS14685	COG1129	ABC transporter
R7A2020_RS14690	COG1172	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS14695	COG1172	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS14700	COG3265	gluconokinase activity
R7A2020_RS14705	COG1959	2 iron, 2 sulfur cluster binding
R7A2020_RS14710	COG4150	thiosulfate binding
R7A2020_RS14725	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
R7A2020_RS14730	COG4208	sulfate ABC transporter
R7A2020_RS14735	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
R7A2020_RS14740	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
R7A2020_RS14750	COG4953	penicillin-binding protein 1C
R7A2020_RS14755	COG2373	Large extracellular alpha-helical protein
R7A2020_RS14760	COG0729	surface antigen
R7A2020_RS14770	COG0747	negative chemotaxis
R7A2020_RS14775	COG0601	transmembrane transport
R7A2020_RS14780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
R7A2020_RS14820	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
R7A2020_RS14825	COG0493	'glutamate synthase
R7A2020_RS14830	COG2226	methyltransferase
R7A2020_RS14845	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
R7A2020_RS14855	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS14870	COG1309	transcriptional regulator
R7A2020_RS14910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
R7A2020_RS14915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
R7A2020_RS14920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
R7A2020_RS14925	COG1522	sequence-specific DNA binding
R7A2020_RS14940	COG0028	Belongs to the TPP enzyme family
R7A2020_RS14945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
R7A2020_RS14960	COG3706	GGDEF domain
R7A2020_RS14970	COG4106	trans-aconitate 2-methyltransferase activity
R7A2020_RS14990	COG2020	methyltransferase activity
R7A2020_RS15005	COG1309	transcriptional regulator
R7A2020_RS15015	COG0300	oxidoreductase activity
R7A2020_RS15020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
R7A2020_RS15035	COG1720	tRNA m6t6A37 methyltransferase activity
R7A2020_RS15060	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS15085	COG3093	addiction module antidote protein HigA
R7A2020_RS15090	COG3549	Plasmid maintenance system killer
R7A2020_RS15105	COG2226	methyltransferase
R7A2020_RS15125	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
R7A2020_RS15130	COG3023	N-Acetylmuramoyl-L-alanine amidase
R7A2020_RS15145	COG0626	cystathionine gamma-synthase activity
R7A2020_RS15150	COG2001	Belongs to the MraZ family
R7A2020_RS15155	COG0275	rRNA processing
R7A2020_RS15170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
R7A2020_RS15180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
R7A2020_RS15185	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
R7A2020_RS15195	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
R7A2020_RS15200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
R7A2020_RS15205	COG0812	UDP-N-acetylmuramate dehydrogenase activity
R7A2020_RS15210	COG1181	Belongs to the D-alanine--D-alanine ligase family
R7A2020_RS15215	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
R7A2020_RS15220	COG0849	cell division
R7A2020_RS15225	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
R7A2020_RS15235	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
R7A2020_RS15245	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
R7A2020_RS15265	COG0006	proline dipeptidase activity
R7A2020_RS15275	COG2264	protein methyltransferase activity
R7A2020_RS15280	COG1999	signal sequence binding
R7A2020_RS15300	COG0300	oxidoreductase activity
R7A2020_RS15320	COG0534	Mate efflux family protein
R7A2020_RS15340	COG5598	trimethylamine methyltransferase
R7A2020_RS15355	COG1609	Transcriptional regulator
R7A2020_RS15390	COG0210	DNA helicase
R7A2020_RS15430	COG1522	sequence-specific DNA binding
R7A2020_RS15445	COG0277	FAD linked oxidase domain protein
R7A2020_RS15460	COG2837	iron assimilation
R7A2020_RS15510	COG2814	Major facilitator Superfamily
R7A2020_RS15530	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
R7A2020_RS15535	COG3585	molybdate ion transport
R7A2020_RS15540	COG0725	ABC transporter, periplasmic molybdate-binding protein
R7A2020_RS15545	COG4149	molybdate abc transporter
R7A2020_RS15550	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
R7A2020_RS15555	COG3585	molybdate ion transport
R7A2020_RS15555	COG2005	Transcriptional regulator
R7A2020_RS15585	COG0330	HflC and HflK could
R7A2020_RS15605	COG0560	Phosphoserine phosphatase
R7A2020_RS15610	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
R7A2020_RS15615	COG2199	diguanylate cyclase activity
R7A2020_RS15615	COG2203	Gaf domain
R7A2020_RS15625	COG1396	sequence-specific DNA binding
R7A2020_RS15640	COG2175	clavaminate synthase activity
R7A2020_RS15660	COG0028	Belongs to the TPP enzyme family
R7A2020_RS15675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
R7A2020_RS15700	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
R7A2020_RS15710	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
R7A2020_RS15715	COG3158	transport of potassium into the cell
R7A2020_RS15720	COG3158	transport of potassium into the cell
R7A2020_RS15735	COG1733	regulation of RNA biosynthetic process
R7A2020_RS15740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
R7A2020_RS15760	COG1309	transcriptional regulator
R7A2020_RS15765	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
R7A2020_RS15790	COG1136	(ABC) transporter
R7A2020_RS15790	COG0577	efflux transmembrane transporter activity
R7A2020_RS15795	COG0577	efflux transmembrane transporter activity
R7A2020_RS15795	COG1136	(ABC) transporter
R7A2020_RS15805	COG0384	phenazine biosynthesis protein PhzF
R7A2020_RS15815	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
R7A2020_RS15820	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
R7A2020_RS15825	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
R7A2020_RS15830	COG1797	cobyrinic acid a,c-diamide synthase activity
R7A2020_RS15895	COG3214	Protein conserved in bacteria
R7A2020_RS15905	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
R7A2020_RS15910	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
R7A2020_RS15915	COG0649	NAD binding
R7A2020_RS15920	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
R7A2020_RS15925	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
R7A2020_RS15930	COG0261	This protein binds to 23S rRNA in the presence of protein L20
R7A2020_RS15930	COG3743	rRNA binding
R7A2020_RS15940	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
R7A2020_RS15945	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
R7A2020_RS15955	COG0713	ATP synthesis coupled electron transport
R7A2020_RS15970	COG1007	ATP synthesis coupled electron transport
R7A2020_RS15990	COG0346	lactoylglutathione lyase activity
R7A2020_RS16000	COG0442	prolyl-tRNA aminoacylation
R7A2020_RS16010	COG1136	(ABC) transporter
R7A2020_RS16025	COG0321	lipoyl(octanoyl) transferase activity
R7A2020_RS16035	COG2205	protein histidine kinase activity
R7A2020_RS16040	COG0745	RESPONSE REGULATOR receiver
R7A2020_RS16070	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
R7A2020_RS16075	COG0045	succinate-CoA ligase (ADP-forming) activity
R7A2020_RS16080	COG2301	Belongs to the HpcH HpaI aldolase family
R7A2020_RS16095	COG2239	Acts as a magnesium transporter
R7A2020_RS16180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
R7A2020_RS16185	COG0402	S-adenosylhomocysteine deaminase activity
R7A2020_RS16195	COG2249	NAD(P)H dehydrogenase (quinone) activity
R7A2020_RS16200	COG2249	NAD(P)H dehydrogenase (quinone) activity
R7A2020_RS16215	COG2040	homocysteine
R7A2020_RS16235	COG2814	Major facilitator Superfamily
R7A2020_RS16245	COG0446	pyridine nucleotide-disulphide oxidoreductase
R7A2020_RS16245	COG0404	The glycine cleavage system catalyzes the degradation of glycine
R7A2020_RS16255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
R7A2020_RS16260	COG3264	Mechanosensitive ion channel
R7A2020_RS16260	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
R7A2020_RS16280	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
R7A2020_RS16295	COG1088	dTDP-glucose 4,6-dehydratase activity
R7A2020_RS16330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
R7A2020_RS16355	COG0583	DNA-binding transcription factor activity
R7A2020_RS16380	COG1410	methionine synthase
R7A2020_RS16380	COG0646	methionine synthase
R7A2020_RS16410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
R7A2020_RS16425	COG5012	cobalamin binding
R7A2020_RS16430	COG5598	trimethylamine methyltransferase
R7A2020_RS16450	COG2304	oxidoreductase activity
R7A2020_RS16460	COG0646	methionine synthase
R7A2020_RS16460	COG1410	methionine synthase
R7A2020_RS16480	COG0006	proline dipeptidase activity
R7A2020_RS16505	COG1505	serine-type exopeptidase activity
R7A2020_RS16530	COG1960	acyl-CoA dehydrogenase activity
R7A2020_RS16535	COG1917	Cupin 2, conserved barrel domain protein
R7A2020_RS16540	COG1492	cobalamin metabolic process
R7A2020_RS16575	COG4172	Belongs to the ABC transporter superfamily
R7A2020_RS16585	COG0601	transmembrane transport
R7A2020_RS16590	COG0747	negative chemotaxis
R7A2020_RS16595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
R7A2020_RS16610	COG3634	alkyl hydroperoxide reductase activity
R7A2020_RS16625	COG1063	alcohol dehydrogenase
R7A2020_RS16630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
R7A2020_RS16635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
R7A2020_RS16640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
R7A2020_RS16685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
R7A2020_RS16695	COG1858	cytochrome C peroxidase
R7A2020_RS16700	COG1522	sequence-specific DNA binding
R7A2020_RS16735	COG3720	iron ion transport
R7A2020_RS16740	COG4558	Periplasmic binding protein
R7A2020_RS16745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
R7A2020_RS16750	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
R7A2020_RS16755	COG1959	2 iron, 2 sulfur cluster binding
R7A2020_RS16760	COG2733	membrane
R7A2020_RS16775	COG0477	Major facilitator Superfamily
R7A2020_RS16785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
R7A2020_RS16790	COG0697	spore germination
R7A2020_RS16820	COG5002	protein histidine kinase activity
R7A2020_RS16860	COG3142	Participates in the control of copper homeostasis
R7A2020_RS16920	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
R7A2020_RS16940	COG0525	valine-tRNA ligase activity
R7A2020_RS16950	COG0129	dihydroxy-acid dehydratase activity
R7A2020_RS16965	COG0708	Exodeoxyribonuclease III
R7A2020_RS16980	COG0232	Belongs to the dGTPase family. Type 2 subfamily
R7A2020_RS16985	COG0018	arginyl-trna synthetase
R7A2020_RS17000	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
R7A2020_RS17005	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
R7A2020_RS17010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
R7A2020_RS17015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
R7A2020_RS17020	COG0805	protein transport
R7A2020_RS17025	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
R7A2020_RS17030	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
R7A2020_RS17035	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
R7A2020_RS17060	COG1862	Preprotein translocase
R7A2020_RS17090	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
R7A2020_RS17135	COG0544	peptidyl-prolyl cis-trans isomerase activity
R7A2020_RS17150	COG0109	protoheme IX farnesyltransferase activity
R7A2020_RS17170	COG1845	cytochrome c oxidase, subunit III
R7A2020_RS17175	COG1845	cytochrome c oxidase, subunit III
R7A2020_RS17180	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
R7A2020_RS17185	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
R7A2020_RS17200	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS17205	COG1250	3-hydroxyacyl-CoA dehydrogenase
R7A2020_RS17210	COG3246	L-lysine catabolic process to acetate
R7A2020_RS17225	COG2003	Belongs to the UPF0758 family
R7A2020_RS17230	COG0024	Methionine aminopeptidase
R7A2020_RS17275	COG0484	heat shock protein binding
R7A2020_RS17295	COG3243	poly(R)-hydroxyalkanoic acid synthase
R7A2020_RS17305	COG0436	Aminotransferase
R7A2020_RS17325	COG1494	fructose-1,6-bisphosphatase
R7A2020_RS17335	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
R7A2020_RS17340	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
R7A2020_RS17345	COG1752	Esterase of the alpha-beta hydrolase superfamily
R7A2020_RS17350	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
R7A2020_RS17355	COG0302	gtp cyclohydrolase
R7A2020_RS17365	COG0583	DNA-binding transcription factor activity
R7A2020_RS17370	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
R7A2020_RS17380	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
R7A2020_RS17385	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
R7A2020_RS17405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
R7A2020_RS17410	COG1309	transcriptional regulator
R7A2020_RS17430	COG2030	dehydratase
R7A2020_RS17445	COG0187	DNA topoisomerase II activity
R7A2020_RS17455	COG4964	Belongs to the GSP D family
R7A2020_RS17505	COG3706	GGDEF domain
R7A2020_RS17510	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
R7A2020_RS17510	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
R7A2020_RS17515	COG0509	glycine decarboxylation via glycine cleavage system
R7A2020_RS17520	COG0404	The glycine cleavage system catalyzes the degradation of glycine
R7A2020_RS17530	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
R7A2020_RS17545	COG1671	Belongs to the UPF0178 family
R7A2020_RS17550	COG3791	Glutathione-dependent formaldehyde-activating
R7A2020_RS17555	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
R7A2020_RS17560	COG4770	biotin carboxylase activity
R7A2020_RS17585	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
R7A2020_RS17610	COG0784	Response regulator, receiver
R7A2020_RS17620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
R7A2020_RS17625	COG2186	Transcriptional regulator
R7A2020_RS17630	COG0626	cystathionine gamma-synthase activity
R7A2020_RS17640	COG1175	transmembrane transport
R7A2020_RS17645	COG0395	ABC-type sugar transport system, permease component
R7A2020_RS17650	COG3842	ATPase activity
R7A2020_RS17655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
R7A2020_RS17680	COG0557	exoribonuclease II activity
R7A2020_RS17685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
R7A2020_RS17695	COG0785	Cytochrome C biogenesis protein
R7A2020_RS17700	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
R7A2020_RS17710	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
R7A2020_RS17720	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
R7A2020_RS17730	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
R7A2020_RS17735	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
R7A2020_RS17740	COG3706	GGDEF domain
R7A2020_RS17745	COG3791	Glutathione-dependent formaldehyde-activating
R7A2020_RS17750	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
R7A2020_RS17780	COG1132	(ABC) transporter
R7A2020_RS17790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
R7A2020_RS17800	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
R7A2020_RS17805	COG0281	malic enzyme
R7A2020_RS17805	COG0280	phosphate acetyltransferase
R7A2020_RS17820	COG2814	Major facilitator Superfamily
R7A2020_RS17825	COG4948	Mandelate Racemase Muconate Lactonizing
R7A2020_RS17835	COG1127	ABC transporter
R7A2020_RS17865	COG0633	Ferredoxin
R7A2020_RS17870	COG0492	ferredoxin-NADP+ reductase activity
R7A2020_RS17885	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
R7A2020_RS17890	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
R7A2020_RS17895	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
R7A2020_RS17905	COG0475	glutathione-regulated potassium exporter activity
R7A2020_RS17905	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
R7A2020_RS17930	COG3768	UPF0283 membrane protein
R7A2020_RS17935	COG3106	COG3106 Predicted ATPase
R7A2020_RS17960	COG0813	purine-nucleoside phosphorylase activity
R7A2020_RS18020	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
R7A2020_RS18030	COG0740	serine-type endopeptidase activity
R7A2020_RS18045	COG0629	single-stranded DNA binding
R7A2020_RS18050	COG1765	OsmC-like protein
R7A2020_RS18055	COG2095	MarC family integral membrane protein
R7A2020_RS18060	COG2755	lipolytic protein G-D-S-L family
R7A2020_RS18060	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
R7A2020_RS18085	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
R7A2020_RS18095	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
R7A2020_RS18115	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
R7A2020_RS18125	COG0343	queuine tRNA-ribosyltransferase activity
R7A2020_RS18140	COG2308	Evidence 4 Homologs of previously reported genes of
R7A2020_RS18175	COG3842	ATPase activity
R7A2020_RS18190	COG0395	ABC-type sugar transport system, permease component
R7A2020_RS18205	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
R7A2020_RS18230	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
R7A2020_RS18230	COG2755	lipolytic protein G-D-S-L family
R7A2020_RS18245	COG0438	transferase activity, transferring glycosyl groups
R7A2020_RS18270	COG0758	DNA mediated transformation
R7A2020_RS18275	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
R7A2020_RS18280	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
R7A2020_RS18285	COG0540	Belongs to the ATCase OTCase family
R7A2020_RS18290	COG1960	acyl-CoA dehydrogenase activity
R7A2020_RS18305	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
R7A2020_RS18310	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
R7A2020_RS18320	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
R7A2020_RS18330	COG0154	amidase activity
R7A2020_RS18335	COG1434	Gram-negative-bacterium-type cell wall biogenesis
R7A2020_RS18345	COG1760	l-serine dehydratase
R7A2020_RS18355	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
R7A2020_RS18360	COG1686	Belongs to the peptidase S11 family
R7A2020_RS18370	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
R7A2020_RS18380	COG0537	adenosine 5'-monophosphoramidase activity
R7A2020_RS18415	COG0052	Belongs to the universal ribosomal protein uS2 family
R7A2020_RS18420	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
R7A2020_RS18425	COG0583	DNA-binding transcription factor activity
R7A2020_RS18435	COG0667	Aldo Keto reductase
R7A2020_RS18440	COG0528	UMP kinase activity
R7A2020_RS18445	COG0233	cytoplasmic translational termination
R7A2020_RS18450	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
R7A2020_RS18460	COG0750	zinc metalloprotease
R7A2020_RS18465	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
R7A2020_RS18470	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
R7A2020_RS18475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
R7A2020_RS18480	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
R7A2020_RS18485	COG3494	Protein of unknown function (DUF1009)
R7A2020_RS18490	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
R7A2020_RS18495	COG0372	Belongs to the citrate synthase family
R7A2020_RS18500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
R7A2020_RS18510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
R7A2020_RS18515	COG1802	Transcriptional regulator
R7A2020_RS18530	COG4120	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS18540	COG3483	tryptophan 2,3-dioxygenase activity
R7A2020_RS18555	COG0303	'Molybdopterin
R7A2020_RS18560	COG0315	cyclic pyranopterin monophosphate synthase activity
R7A2020_RS18565	COG0134	indole-3-glycerol-phosphate synthase activity
R7A2020_RS18570	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
R7A2020_RS18575	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
R7A2020_RS18580	COG0149	triose-phosphate isomerase activity
R7A2020_RS18595	COG0504	CTP synthase activity
R7A2020_RS18605	COG1953	Uracil, thiamine, allantoin
R7A2020_RS18610	COG0583	DNA-binding transcription factor activity
R7A2020_RS18615	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
R7A2020_RS18620	COG2267	carboxylic ester hydrolase activity
R7A2020_RS18625	COG0747	negative chemotaxis
R7A2020_RS18630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
R7A2020_RS18640	COG0444	Belongs to the ABC transporter superfamily
R7A2020_RS18645	COG4608	Belongs to the ABC transporter superfamily
R7A2020_RS18675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
R7A2020_RS18700	COG3306	glycosyltransferase involved in LPS biosynthesis
R7A2020_RS18720	COG1672	PFAM Archaeal ATPase
R7A2020_RS18720	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
R7A2020_RS18750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
R7A2020_RS18765	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
R7A2020_RS18770	COG2202	Pas domain
R7A2020_RS18770	COG2205	protein histidine kinase activity
R7A2020_RS18775	COG1525	nuclease
R7A2020_RS18780	COG0625	glutathione transferase activity
R7A2020_RS18785	COG1573	uracil-dna glycosylase
R7A2020_RS18790	COG1522	sequence-specific DNA binding
R7A2020_RS18810	COG2084	Dehydrogenase
R7A2020_RS18825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
R7A2020_RS18830	COG1763	Mo-molybdopterin cofactor biosynthetic process
R7A2020_RS18835	COG0746	molybdenum cofactor guanylyltransferase activity
R7A2020_RS18855	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
R7A2020_RS18870	COG1846	Transcriptional regulator
R7A2020_RS18885	COG1309	transcriptional regulator
R7A2020_RS18890	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS18920	COG0546	phosphoglycolate phosphatase activity
R7A2020_RS18925	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
R7A2020_RS18940	COG2239	Acts as a magnesium transporter
R7A2020_RS18945	COG4178	(ABC) transporter
R7A2020_RS18960	COG4166	transmembrane transport
R7A2020_RS18975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
R7A2020_RS18990	COG1183	phosphatidylcholine synthase activity
R7A2020_RS19020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
R7A2020_RS19025	COG0861	Integral membrane protein TerC family
R7A2020_RS19065	COG1686	Belongs to the peptidase S11 family
R7A2020_RS19070	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
R7A2020_RS19090	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
R7A2020_RS19095	COG0084	hydrolase, TatD family'
R7A2020_RS19100	COG1234	tRNA 3'-trailer cleavage
R7A2020_RS19130	COG0670	Belongs to the BI1 family
R7A2020_RS19155	COG3956	TIGRFAM MazG family protein
R7A2020_RS19160	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
R7A2020_RS19165	COG1923	regulation of RNA biosynthetic process
R7A2020_RS19170	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
R7A2020_RS19175	COG2204	response regulator
R7A2020_RS19180	COG5000	phosphorelay sensor kinase activity
R7A2020_RS19185	COG2204	response regulator
R7A2020_RS19190	COG3852	Histidine kinase
R7A2020_RS19200	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
R7A2020_RS19200	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
R7A2020_RS19205	COG1546	Belongs to the CinA family
R7A2020_RS19215	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
R7A2020_RS19225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
R7A2020_RS19240	COG0508	dehydrogenase complex catalyzes the overall conversion of
R7A2020_RS19245	COG0022	dehydrogenase e1 component
R7A2020_RS19245	COG0508	dehydrogenase complex catalyzes the overall conversion of
R7A2020_RS19250	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
R7A2020_RS19255	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
R7A2020_RS19270	COG0148	phosphopyruvate hydratase activity
R7A2020_RS19285	COG2877	3-deoxy-8-phosphooctulonate synthase activity
R7A2020_RS19300	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
R7A2020_RS19310	COG0737	Belongs to the 5'-nucleotidase family
R7A2020_RS19315	COG1252	NADH dehydrogenase
R7A2020_RS19320	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
R7A2020_RS19325	COG1522	sequence-specific DNA binding
R7A2020_RS19330	COG0686	Belongs to the AlaDH PNT family
R7A2020_RS19355	COG2897	thiosulfate sulfurtransferase activity
R7A2020_RS19360	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
R7A2020_RS19370	COG0300	oxidoreductase activity
R7A2020_RS19380	COG0513	Belongs to the DEAD box helicase family
R7A2020_RS19385	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
R7A2020_RS19395	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
R7A2020_RS19395	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
R7A2020_RS19400	COG0347	Belongs to the P(II) protein family
R7A2020_RS19405	COG0174	glutamine synthetase
R7A2020_RS19415	COG0174	glutamine synthetase
R7A2020_RS19445	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
R7A2020_RS19465	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
R7A2020_RS19475	COG0203	ribosomal protein L17
R7A2020_RS19480	COG0202	RNA polymerase activity
R7A2020_RS19485	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
R7A2020_RS19490	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
R7A2020_RS19495	COG0563	adenylate kinase activity
R7A2020_RS19505	COG0200	Binds to the 23S rRNA
R7A2020_RS19510	COG1841	ribosomal large subunit assembly
R7A2020_RS19515	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
R7A2020_RS19520	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
R7A2020_RS19525	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
R7A2020_RS19530	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
R7A2020_RS19535	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
R7A2020_RS19540	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
R7A2020_RS19545	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
R7A2020_RS19550	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
R7A2020_RS19555	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
R7A2020_RS19560	COG0255	Belongs to the universal ribosomal protein uL29 family
R7A2020_RS19565	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
R7A2020_RS19570	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
R7A2020_RS19575	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
R7A2020_RS19580	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
R7A2020_RS19585	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
R7A2020_RS19590	COG0089	rRNA binding
R7A2020_RS19595	COG0088	Forms part of the polypeptide exit tunnel
R7A2020_RS19600	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
R7A2020_RS19605	COG0051	transcription antitermination factor activity, RNA binding
R7A2020_RS19610	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
R7A2020_RS19615	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
R7A2020_RS19620	COG0049	tRNA binding
R7A2020_RS19625	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
R7A2020_RS19645	COG4122	O-methyltransferase activity
R7A2020_RS19650	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
R7A2020_RS19655	COG0085	RNA polymerase activity
R7A2020_RS19660	COG0222	ribosome binding
R7A2020_RS19665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
R7A2020_RS19670	COG0081	regulation of translation
R7A2020_RS19675	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
R7A2020_RS19685	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
R7A2020_RS19705	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
R7A2020_RS19720	COG2261	transglycosylase associated protein
R7A2020_RS19740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
R7A2020_RS19745	COG2084	Dehydrogenase
R7A2020_RS19750	COG3622	Belongs to the hyi family
R7A2020_RS19755	COG3960	tartronate-semialdehyde synthase activity
R7A2020_RS19760	COG1414	Transcriptional regulator
R7A2020_RS19820	COG0583	DNA-binding transcription factor activity
R7A2020_RS19835	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
R7A2020_RS19845	COG4208	sulfate ABC transporter
R7A2020_RS19850	COG3842	ATPase activity
R7A2020_RS19855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
R7A2020_RS19865	COG0154	amidase activity
R7A2020_RS19880	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
R7A2020_RS19885	COG0513	Belongs to the DEAD box helicase family
R7A2020_RS19895	COG2885	chlorophyll binding
R7A2020_RS19915	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
R7A2020_RS19920	COG0860	N-Acetylmuramoyl-L-alanine amidase
R7A2020_RS19925	COG1530	ribonuclease E activity
R7A2020_RS19930	COG2066	Belongs to the glutaminase family
R7A2020_RS19935	COG0436	Aminotransferase
R7A2020_RS19950	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
R7A2020_RS19955	COG0511	ligase activity, forming carbon-carbon bonds
R7A2020_RS19965	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
R7A2020_RS19985	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
R7A2020_RS19990	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
R7A2020_RS20005	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
R7A2020_RS20010	COG3811	Belongs to the UPF0386 family
R7A2020_RS20040	COG0666	response to abiotic stimulus
R7A2020_RS20090	COG1278	Cold shock
R7A2020_RS20095	COG0346	lactoylglutathione lyase activity
R7A2020_RS20110	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
R7A2020_RS20125	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
R7A2020_RS20135	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
R7A2020_RS20155	COG2986	histidine ammonia-lyase
R7A2020_RS20160	COG0494	nUDIX hydrolase
R7A2020_RS20165	COG1902	pentaerythritol trinitrate reductase activity
R7A2020_RS20190	COG2267	carboxylic ester hydrolase activity
R7A2020_RS20195	COG1546	Belongs to the CinA family
R7A2020_RS20195	COG1058	Belongs to the CinA family
R7A2020_RS20205	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
R7A2020_RS20220	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
R7A2020_RS20240	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
R7A2020_RS20250	COG0583	DNA-binding transcription factor activity
R7A2020_RS20275	COG0586	Pfam SNARE associated Golgi protein
R7A2020_RS20290	COG1968	undecaprenyl-diphosphatase activity
R7A2020_RS20330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
R7A2020_RS20335	COG3246	L-lysine catabolic process to acetate
R7A2020_RS20340	COG1683	Conserved Protein
R7A2020_RS20360	COG0667	Aldo Keto reductase
R7A2020_RS20390	COG2068	MobA-Related Protein
R7A2020_RS20395	COG3608	succinylglutamate desuccinylase aspartoacylase
R7A2020_RS20395	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
R7A2020_RS20410	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
R7A2020_RS20415	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
R7A2020_RS20425	COG3191	aminopeptidase activity
R7A2020_RS20445	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
R7A2020_RS20450	COG2514	catechol 2,3-dioxygenase activity
R7A2020_RS20475	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
R7A2020_RS20480	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
R7A2020_RS20490	COG0047	phosphoribosylformylglycinamidine synthase activity
R7A2020_RS20515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
R7A2020_RS20525	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
R7A2020_RS20555	COG0483	inositol monophosphate 1-phosphatase activity
R7A2020_RS20560	COG0037	tRNA processing
R7A2020_RS20565	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
R7A2020_RS20580	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
R7A2020_RS20585	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
R7A2020_RS20590	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
R7A2020_RS20600	COG0538	isocitrate dehydrogenase activity
R7A2020_RS20620	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
R7A2020_RS20625	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
R7A2020_RS20635	COG2313	pseudouridylate synthase activity
R7A2020_RS20645	COG3791	Glutathione-dependent formaldehyde-activating
R7A2020_RS20650	COG0316	Belongs to the HesB IscA family
R7A2020_RS20655	COG2151	metal-sulfur cluster biosynthetic enzyme
R7A2020_RS20660	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
R7A2020_RS20665	COG0719	Fe-S assembly protein
R7A2020_RS20670	COG0396	ATPase activity
R7A2020_RS20680	COG0719	Fe-S assembly protein
R7A2020_RS20690	COG2945	thiolester hydrolase activity
R7A2020_RS20700	COG0671	phosphoesterase, PA-phosphatase related
R7A2020_RS20705	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
R7A2020_RS20715	COG0463	Glycosyl transferase, family 2
R7A2020_RS20720	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
R7A2020_RS20730	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
R7A2020_RS20745	COG0739	heme binding
R7A2020_RS20750	COG0277	FAD linked oxidase domain protein
R7A2020_RS20755	COG2186	Transcriptional regulator
R7A2020_RS20780	COG0006	proline dipeptidase activity
R7A2020_RS20800	COG1172	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS20810	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
R7A2020_RS20825	COG4974	Belongs to the 'phage' integrase family
R7A2020_RS20860	COG3550	peptidyl-serine autophosphorylation
R7A2020_RS20870	COG4957	zinc ion binding
R7A2020_RS21015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
R7A2020_RS21025	COG3842	ATPase activity
R7A2020_RS21035	COG1175	transmembrane transport
R7A2020_RS21040	COG0395	ABC-type sugar transport system, permease component
R7A2020_RS21070	COG0776	regulation of translation
R7A2020_RS21080	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
R7A2020_RS21085	COG0740	serine-type endopeptidase activity
R7A2020_RS21095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
R7A2020_RS21100	COG2124	cytochrome p450
R7A2020_RS21120	COG1832	CoA-binding protein
R7A2020_RS21125	COG1120	ATPase activity
R7A2020_RS21145	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
R7A2020_RS21150	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
R7A2020_RS21165	COG0010	Belongs to the arginase family
R7A2020_RS21170	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
R7A2020_RS21180	COG1612	heme a metabolic process
R7A2020_RS21205	COG3842	ATPase activity
R7A2020_RS21220	COG0395	ABC-type sugar transport system, permease component
R7A2020_RS21245	COG0297	glycogen (starch) synthase activity
R7A2020_RS21250	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
R7A2020_RS21265	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
R7A2020_RS21270	COG1396	sequence-specific DNA binding
R7A2020_RS21295	COG0776	regulation of translation
R7A2020_RS21300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
R7A2020_RS21305	COG0416	fatty acid biosynthetic process
R7A2020_RS21320	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
R7A2020_RS21325	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
R7A2020_RS21330	COG1174	glycine betaine transport
R7A2020_RS21335	COG1125	glycine betaine transport
R7A2020_RS21340	COG1174	glycine betaine transport
R7A2020_RS21345	COG1732	Glycine betaine
R7A2020_RS21350	COG2814	Major facilitator Superfamily
R7A2020_RS21355	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
R7A2020_RS21360	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
R7A2020_RS21370	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
R7A2020_RS21370	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
R7A2020_RS21375	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
R7A2020_RS21390	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
R7A2020_RS21395	COG0025	NhaP-type Na H and K H
R7A2020_RS21400	COG2989	Protein conserved in bacteria
R7A2020_RS21425	COG1024	Enoyl-CoA hydratase
R7A2020_RS21435	COG0113	porphobilinogen synthase activity
R7A2020_RS21450	COG0667	Aldo Keto reductase
R7A2020_RS21515	COG0306	phosphate transporter
R7A2020_RS21520	COG1392	Phosphate transport regulator
R7A2020_RS21540	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
R7A2020_RS21550	COG0628	permease
R7A2020_RS21555	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
R7A2020_RS21565	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
R7A2020_RS21580	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
R7A2020_RS21610	COG0477	Major facilitator Superfamily
R7A2020_RS21615	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
R7A2020_RS21670	COG0714	Associated with various cellular activities
R7A2020_RS21700	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
R7A2020_RS21705	COG1132	(ABC) transporter
R7A2020_RS21710	COG3459	Glycosyltransferase 36 associated
R7A2020_RS21720	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
R7A2020_RS21730	COG2986	histidine ammonia-lyase
R7A2020_RS21735	COG1228	amidohydrolase
R7A2020_RS21740	COG0402	S-adenosylhomocysteine deaminase activity
R7A2020_RS21745	COG2188	Transcriptional regulator
R7A2020_RS21750	COG0251	oxidation-reduction process
R7A2020_RS21760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
R7A2020_RS21765	COG0803	Belongs to the bacterial solute-binding protein 9 family
R7A2020_RS21800	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
R7A2020_RS21810	COG1063	alcohol dehydrogenase
R7A2020_RS21815	COG0156	8-amino-7-oxononanoate synthase activity
R7A2020_RS21825	COG0726	polysaccharide deacetylase
R7A2020_RS21840	COG1902	pentaerythritol trinitrate reductase activity
R7A2020_RS21840	COG0446	pyridine nucleotide-disulphide oxidoreductase
R7A2020_RS21845	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
R7A2020_RS21870	COG0747	negative chemotaxis
R7A2020_RS21875	COG5598	trimethylamine methyltransferase
R7A2020_RS21885	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
R7A2020_RS21915	COG1663	tetraacyldisaccharide 4'-kinase activity
R7A2020_RS21920	COG1519	Transferase
R7A2020_RS21935	COG0483	inositol monophosphate 1-phosphatase activity
R7A2020_RS21940	COG0312	modulator of DNA gyrase
R7A2020_RS21950	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
R7A2020_RS21955	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
R7A2020_RS21975	COG0612	Peptidase, M16
R7A2020_RS21980	COG0612	Peptidase, M16
R7A2020_RS21985	COG0742	ribosomal rna small subunit methyltransferase
R7A2020_RS21995	COG0590	tRNA wobble adenosine to inosine editing
R7A2020_RS22005	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
R7A2020_RS22020	COG3511	phospholipase C
R7A2020_RS22030	COG0196	riboflavin kinase activity
R7A2020_RS22045	COG1280	lysine exporter protein (LysE YggA)
R7A2020_RS22065	COG2340	Cysteine-rich secretory protein family
R7A2020_RS22070	COG2814	Major facilitator Superfamily
R7A2020_RS22075	COG1566	PFAM secretion protein HlyD family protein
R7A2020_RS22085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
R7A2020_RS22095	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
R7A2020_RS22105	COG0697	spore germination
R7A2020_RS22110	COG1609	Transcriptional regulator
R7A2020_RS22115	COG1172	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS22120	COG1129	ABC transporter
R7A2020_RS22130	COG2207	Transcriptional regulator
R7A2020_RS22130	COG3708	Transcriptional regulator
R7A2020_RS22140	COG1846	Transcriptional regulator
R7A2020_RS22140	COG0456	acetyltransferase
R7A2020_RS22165	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
R7A2020_RS22170	COG0459	protein refolding
R7A2020_RS22195	COG1063	alcohol dehydrogenase
R7A2020_RS22200	COG1764	response to oxidative stress
R7A2020_RS22210	COG1280	lysine exporter protein (LysE YggA)
R7A2020_RS22235	COG1278	Cold shock
R7A2020_RS22245	COG0640	Transcriptional regulator
R7A2020_RS22255	COG3237	CsbD-like
R7A2020_RS22280	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS22290	COG0114	fumarate hydratase activity
R7A2020_RS22295	COG2259	Doxx family
R7A2020_RS22325	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
R7A2020_RS22335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
R7A2020_RS22350	COG1126	abc transporter atp-binding protein
R7A2020_RS22355	COG0765	amino acid transport
R7A2020_RS22360	COG4597	amino acid ABC transporter
R7A2020_RS22365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
R7A2020_RS22385	COG0626	cystathionine gamma-synthase activity
R7A2020_RS22400	COG1595	DNA-templated transcription, initiation
R7A2020_RS22410	COG3794	PFAM blue (type 1) copper domain protein
R7A2020_RS22415	COG1024	Enoyl-CoA hydratase
R7A2020_RS22440	COG0438	transferase activity, transferring glycosyl groups
R7A2020_RS22445	COG5002	protein histidine kinase activity
R7A2020_RS22445	COG5001	Diguanylate cyclase
R7A2020_RS22445	COG3447	MASE1 domain protein
R7A2020_RS22460	COG1525	nuclease
R7A2020_RS22510	COG1793	dna ligase
R7A2020_RS22555	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
R7A2020_RS22725	COG1309	transcriptional regulator
R7A2020_RS22775	COG3750	Belongs to the UPF0335 family
R7A2020_RS22875	COG0628	permease
R7A2020_RS22885	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
R7A2020_RS22890	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
R7A2020_RS22930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
R7A2020_RS22940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
R7A2020_RS22945	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
R7A2020_RS22970	COG1473	amidohydrolase
R7A2020_RS22985	COG1522	sequence-specific DNA binding
R7A2020_RS22990	COG2072	flavoprotein involved in K transport
R7A2020_RS22995	COG0243	molybdopterin cofactor binding
R7A2020_RS23000	COG0488	(ABC) transporter
R7A2020_RS23005	COG4957	zinc ion binding
R7A2020_RS23045	COG0105	UTP biosynthetic process
R7A2020_RS23050	COG3126	Type III secretion system lipoprotein chaperone (YscW)
R7A2020_RS23055	COG0314	molybdopterin synthase activity
R7A2020_RS23065	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
R7A2020_RS23070	COG0322	excinuclease ABC activity
R7A2020_RS23090	COG0625	glutathione transferase activity
R7A2020_RS23105	COG1280	lysine exporter protein (LysE YggA)
R7A2020_RS23115	COG1309	transcriptional regulator
R7A2020_RS23140	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
R7A2020_RS23160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
R7A2020_RS23205	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
R7A2020_RS23230	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
R7A2020_RS23235	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
R7A2020_RS23245	COG0194	GDP metabolic process
R7A2020_RS23250	COG1561	YicC-like family, N-terminal region
R7A2020_RS23255	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
R7A2020_RS23260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
R7A2020_RS23265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
R7A2020_RS23275	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
R7A2020_RS23280	COG1368	sulfuric ester hydrolase activity
R7A2020_RS23290	COG0360	Binds together with S18 to 16S ribosomal RNA
R7A2020_RS23295	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
R7A2020_RS23300	COG0359	binds to the 23S rRNA
R7A2020_RS23305	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
R7A2020_RS23310	COG1742	UPF0060 membrane protein
R7A2020_RS23320	COG5507	3-demethylubiquinone-9 3-methyltransferase
R7A2020_RS23330	COG4941	Belongs to the sigma-70 factor family
R7A2020_RS23350	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
R7A2020_RS23355	COG4221	oxidoreductase activity
R7A2020_RS23370	COG0697	spore germination
R7A2020_RS23380	COG0583	DNA-binding transcription factor activity
R7A2020_RS23395	COG1183	phosphatidylcholine synthase activity
R7A2020_RS23400	COG0688	phosphatidylethanolamine metabolic process
R7A2020_RS23405	COG3386	PFAM SMP-30 Gluconolaconase
R7A2020_RS23415	COG5265	(ABC) transporter
R7A2020_RS23420	COG0640	Transcriptional regulator
R7A2020_RS23425	COG0583	DNA-binding transcription factor activity
R7A2020_RS23445	COG0583	DNA-binding transcription factor activity
R7A2020_RS23465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
R7A2020_RS23490	COG0215	cysteine-tRNA ligase activity
R7A2020_RS23525	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
R7A2020_RS23530	COG0354	folic acid binding
R7A2020_RS23535	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
R7A2020_RS23540	COG5001	Diguanylate cyclase
R7A2020_RS23545	COG0583	DNA-binding transcription factor activity
R7A2020_RS23550	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS23560	COG0583	DNA-binding transcription factor activity
R7A2020_RS23585	COG1595	DNA-templated transcription, initiation
R7A2020_RS23600	COG1381	Involved in DNA repair and RecF pathway recombination
R7A2020_RS23610	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
R7A2020_RS23615	COG0571	ribonuclease III activity
R7A2020_RS23620	COG0681	Belongs to the peptidase S26 family
R7A2020_RS23625	COG0736	holo-[acyl-carrier-protein] synthase activity
R7A2020_RS23640	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
R7A2020_RS23650	COG1758	RNA polymerase activity
R7A2020_RS23670	COG1733	regulation of RNA biosynthetic process
R7A2020_RS23680	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
R7A2020_RS23685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
R7A2020_RS23690	COG0741	lytic transglycosylase activity
R7A2020_RS23720	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
R7A2020_RS23725	COG0456	acetyltransferase
R7A2020_RS23725	COG1846	Transcriptional regulator
R7A2020_RS23730	COG1254	Belongs to the acylphosphatase family
R7A2020_RS23740	COG1960	acyl-CoA dehydrogenase activity
R7A2020_RS23745	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
R7A2020_RS23750	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
R7A2020_RS23760	COG4770	biotin carboxylase activity
R7A2020_RS23810	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
R7A2020_RS23860	COG0308	aminopeptidase N
R7A2020_RS23865	COG2202	Pas domain
R7A2020_RS23865	COG2205	protein histidine kinase activity
R7A2020_RS23875	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
R7A2020_RS23885	COG0745	RESPONSE REGULATOR receiver
R7A2020_RS23890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
R7A2020_RS23895	COG3088	subunit of a heme lyase
R7A2020_RS23900	COG1138	Cytochrome C-type biogenesis protein
R7A2020_RS23905	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
R7A2020_RS23910	COG4235	cytochrome complex assembly
R7A2020_RS23920	COG5002	protein histidine kinase activity
R7A2020_RS23925	COG0745	RESPONSE REGULATOR receiver
R7A2020_RS23940	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS23960	COG3842	ATPase activity
R7A2020_RS23995	COG1172	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS24010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
R7A2020_RS24015	COG0159	tryptophan synthase activity
R7A2020_RS24025	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
R7A2020_RS24055	COG3429	Glucose-6-phosphate dehydrogenase subunit
R7A2020_RS24055	COG3409	Peptidoglycan-binding domain 1 protein
R7A2020_RS24060	COG2205	protein histidine kinase activity
R7A2020_RS24070	COG2166	iron-sulfur cluster assembly
R7A2020_RS24090	COG1280	lysine exporter protein (LysE YggA)
R7A2020_RS24100	COG2010	Cytochrome c
R7A2020_RS24105	COG3909	cytochrome
R7A2020_RS24110	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
R7A2020_RS24115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
R7A2020_RS24125	COG1376	ErfK ybiS ycfS ynhG family protein
R7A2020_RS24130	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
R7A2020_RS24135	COG3622	Belongs to the hyi family
R7A2020_RS24145	COG1129	ABC transporter
R7A2020_RS24170	COG0433	COG0433 Predicted ATPase
R7A2020_RS24185	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
R7A2020_RS24200	COG0183	Belongs to the thiolase family
R7A2020_RS24205	COG1309	transcriptional regulator
R7A2020_RS24210	COG3119	arylsulfatase activity
R7A2020_RS24220	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
R7A2020_RS24225	COG1012	belongs to the aldehyde dehydrogenase family
R7A2020_RS24270	COG4172	Belongs to the ABC transporter superfamily
R7A2020_RS24275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
R7A2020_RS24280	COG0601	transmembrane transport
R7A2020_RS24285	COG4166	transmembrane transport
R7A2020_RS24300	COG0366	Alpha amylase catalytic
R7A2020_RS24305	COG1523	belongs to the glycosyl hydrolase 13 family
R7A2020_RS24310	COG0033	Phosphoglucomutase
R7A2020_RS24315	COG0297	glycogen (starch) synthase activity
R7A2020_RS24320	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
R7A2020_RS24325	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
R7A2020_RS24330	COG0058	SHG alpha-glucan phosphorylase activity
R7A2020_RS24370	COG1218	3'(2'),5'-bisphosphate nucleotidase
R7A2020_RS24380	COG0175	sulfate reduction
R7A2020_RS24385	COG3307	-O-antigen
R7A2020_RS24405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
R7A2020_RS24410	COG1215	transferase activity, transferring glycosyl groups
R7A2020_RS24465	COG0463	Glycosyl transferase, family 2
R7A2020_RS24480	COG1091	dTDP-4-dehydrorhamnose reductase activity
R7A2020_RS24490	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
R7A2020_RS24495	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
R7A2020_RS24505	COG1268	BioY protein
R7A2020_RS24520	COG1177	transmembrane transport
R7A2020_RS24525	COG1176	ABC-type spermidine putrescine transport system, permease component I
R7A2020_RS24530	COG3842	ATPase activity
R7A2020_RS24540	COG1609	Transcriptional regulator
R7A2020_RS24570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
R7A2020_RS24570	COG0574	Belongs to the PEP-utilizing enzyme family
R7A2020_RS24590	COG1196	nuclear chromosome segregation
R7A2020_RS24595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
R7A2020_RS24605	COG1194	a g-specific adenine glycosylase
R7A2020_RS24615	COG2189	Belongs to the N(4) N(6)-methyltransferase family
R7A2020_RS24620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
R7A2020_RS24635	COG0612	Peptidase, M16
R7A2020_RS24640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
R7A2020_RS24650	COG1678	Uncharacterized ACR, COG1678
R7A2020_RS24660	COG0678	peroxiredoxin activity
R7A2020_RS24675	COG0328	RNA-DNA hybrid ribonuclease activity
R7A2020_RS24680	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
R7A2020_RS24685	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
R7A2020_RS24690	COG3346	SURF1 family
R7A2020_RS24710	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
R7A2020_RS24720	COG0109	protoheme IX farnesyltransferase activity
R7A2020_RS24725	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
R7A2020_RS24730	COG1565	acr, cog1565
R7A2020_RS24730	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
R7A2020_RS24740	COG0312	modulator of DNA gyrase
R7A2020_RS24765	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
R7A2020_RS24785	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
R7A2020_RS24790	COG1741	Belongs to the pirin family
R7A2020_RS24800	COG1722	exodeoxyribonuclease VII activity
R7A2020_RS24805	COG0123	including yeast histone deacetylase and acetoin utilization protein
R7A2020_RS24810	COG0778	Nitroreductase
R7A2020_RS24820	COG1309	transcriptional regulator
R7A2020_RS24835	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
R7A2020_RS24835	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
R7A2020_RS24840	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
R7A2020_RS24850	COG0406	alpha-ribazole phosphatase activity
R7A2020_RS24855	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
R7A2020_RS24860	COG0484	heat shock protein binding
R7A2020_RS24870	COG0259	pyridoxamine-phosphate oxidase activity
R7A2020_RS24875	COG1024	Enoyl-CoA hydratase
R7A2020_RS24880	COG1960	acyl-CoA dehydrogenase activity
R7A2020_RS24895	COG0151	Belongs to the GarS family
R7A2020_RS24905	COG0583	DNA-binding transcription factor activity
R7A2020_RS24910	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
R7A2020_RS24920	COG0277	FAD linked oxidase domain protein
R7A2020_RS24925	COG0009	L-threonylcarbamoyladenylate synthase
R7A2020_RS24945	COG0751	glycine-tRNA ligase activity
R7A2020_RS24950	COG0752	glycyl-tRNA synthetase alpha subunit
R7A2020_RS24980	COG0142	geranyltranstransferase activity
R7A2020_RS25005	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
R7A2020_RS25010	COG0521	Mo-molybdopterin cofactor biosynthetic process
R7A2020_RS25030	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
R7A2020_RS25035	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
R7A2020_RS25040	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
R7A2020_RS25045	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
R7A2020_RS25050	COG0356	it plays a direct role in the translocation of protons across the membrane
R7A2020_RS25065	COG2814	Major facilitator Superfamily
R7A2020_RS25070	COG0583	DNA-binding transcription factor activity
R7A2020_RS25075	COG1160	GTP binding
R7A2020_RS25080	COG2976	Protein conserved in bacteria
R7A2020_RS25090	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
R7A2020_RS25095	COG0477	Major facilitator Superfamily
R7A2020_RS25105	COG0583	DNA-binding transcription factor activity
R7A2020_RS25110	COG2309	aminopeptidase activity
R7A2020_RS25120	COG1393	Belongs to the ArsC family
R7A2020_RS25140	COG3842	ATPase activity
R7A2020_RS25155	COG1177	transmembrane transport
R7A2020_RS25160	COG1176	ABC-type spermidine putrescine transport system, permease component I
R7A2020_RS25175	COG4948	Mandelate Racemase Muconate Lactonizing
R7A2020_RS25190	COG1129	ABC transporter
R7A2020_RS25200	COG2017	converts alpha-aldose to the beta-anomer
R7A2020_RS25220	COG1172	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS25235	COG1309	transcriptional regulator
R7A2020_RS25250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
R7A2020_RS25265	COG4948	Mandelate Racemase Muconate Lactonizing
R7A2020_RS25275	COG0747	negative chemotaxis
R7A2020_RS25280	COG0601	transmembrane transport
R7A2020_RS25300	COG0747	negative chemotaxis
R7A2020_RS25340	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS25345	COG2113	Glycine betaine
R7A2020_RS25350	COG4175	Glycine betaine
R7A2020_RS25355	COG4176	ABC-type proline glycine betaine transport system permease component
R7A2020_RS25385	COG0404	The glycine cleavage system catalyzes the degradation of glycine
R7A2020_RS25405	COG0531	amino acid
R7A2020_RS25420	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
R7A2020_RS25425	COG2218	PFAM glutamate synthase alpha subunit domain protein
R7A2020_RS25430	COG0069	glutamate synthase activity
R7A2020_RS25440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
R7A2020_RS25445	COG4311	Sarcosine oxidase, delta subunit
R7A2020_RS25450	COG0404	The glycine cleavage system catalyzes the degradation of glycine
R7A2020_RS25450	COG0446	pyridine nucleotide-disulphide oxidoreductase
R7A2020_RS25460	COG0404	The glycine cleavage system catalyzes the degradation of glycine
R7A2020_RS25490	COG0318	PFAM AMP-dependent synthetase and ligase
R7A2020_RS25500	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS25500	COG3347	Dehydrogenase
R7A2020_RS25515	COG1129	ABC transporter
R7A2020_RS25520	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
R7A2020_RS25525	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
R7A2020_RS25530	COG1522	sequence-specific DNA binding
R7A2020_RS25540	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
R7A2020_RS25545	COG2376	Dihydroxyacetone kinase
R7A2020_RS25550	COG1461	Dihydroxyacetone kinase
R7A2020_RS25555	COG0698	ribose 5-phosphate isomerase
R7A2020_RS25560	COG0149	triose-phosphate isomerase activity
R7A2020_RS25600	COG3842	ATPase activity
R7A2020_RS25615	COG1175	transmembrane transport
R7A2020_RS25620	COG1653	transport
R7A2020_RS25630	COG3552	Protein containing von Willebrand factor type A (VWA) domain
R7A2020_RS25640	COG0714	Associated with various cellular activities
R7A2020_RS25660	COG3842	ATPase activity
R7A2020_RS25685	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
R7A2020_RS25695	COG0174	glutamine synthetase
R7A2020_RS25700	COG1737	Transcriptional regulator
R7A2020_RS25705	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
R7A2020_RS25710	COG2971	BadF BadG BcrA BcrD
R7A2020_RS25715	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
R7A2020_RS25720	COG0747	negative chemotaxis
R7A2020_RS25750	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
R7A2020_RS25760	COG2204	response regulator
R7A2020_RS25765	COG4191	Histidine kinase
R7A2020_RS25770	COG1301	dicarboxylic acid transport
R7A2020_RS25775	COG1940	carbohydrate kinase activity
R7A2020_RS25795	COG0673	inositol 2-dehydrogenase activity
R7A2020_RS25805	COG0395	ABC-type sugar transport system, permease component
R7A2020_RS25810	COG1175	transmembrane transport
R7A2020_RS25825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
R7A2020_RS25835	COG1349	DNA-binding transcription factor activity
R7A2020_RS25855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
R7A2020_RS25860	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
R7A2020_RS25880	COG3485	protocatechuate 3,4-dioxygenase
R7A2020_RS25885	COG3485	protocatechuate 3,4-dioxygenase
R7A2020_RS25890	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
R7A2020_RS25895	COG0596	Alpha beta hydrolase
R7A2020_RS25900	COG0583	DNA-binding transcription factor activity
R7A2020_RS25935	COG1012	belongs to the aldehyde dehydrogenase family
R7A2020_RS25970	COG3842	ATPase activity
R7A2020_RS25975	COG1176	ABC-type spermidine putrescine transport system, permease component I
R7A2020_RS25980	COG1177	transmembrane transport
R7A2020_RS25985	COG0277	FAD linked oxidase domain protein
R7A2020_RS26000	COG0667	Aldo Keto reductase
R7A2020_RS26030	COG0559	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS26040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
R7A2020_RS26045	COG1802	Transcriptional regulator
R7A2020_RS26050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
R7A2020_RS26060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
R7A2020_RS26075	COG0583	DNA-binding transcription factor activity
R7A2020_RS26110	COG3618	amidohydrolase
R7A2020_RS26125	COG1175	transmembrane transport
R7A2020_RS26130	COG0395	ABC-type sugar transport system, permease component
R7A2020_RS26135	COG3842	ATPase activity
R7A2020_RS26140	COG4948	Mandelate Racemase Muconate Lactonizing
R7A2020_RS26145	COG3254	rhamnose metabolic process
R7A2020_RS26170	COG3608	succinylglutamate desuccinylase aspartoacylase
R7A2020_RS26175	COG0006	proline dipeptidase activity
R7A2020_RS26180	COG2423	ornithine cyclodeaminase activity
R7A2020_RS26185	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
R7A2020_RS26195	COG0765	amino acid transport
R7A2020_RS26200	COG0765	amino acid transport
R7A2020_RS26205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
R7A2020_RS26210	COG1126	abc transporter atp-binding protein
R7A2020_RS26215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
R7A2020_RS26220	COG1522	sequence-specific DNA binding
R7A2020_RS26225	COG1012	belongs to the aldehyde dehydrogenase family
R7A2020_RS26230	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
R7A2020_RS26235	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS26235	COG3321	synthase
R7A2020_RS26235	COG0604	alcohol dehydrogenase
R7A2020_RS26240	COG2986	histidine ammonia-lyase
R7A2020_RS26250	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
R7A2020_RS26255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
R7A2020_RS26260	COG1132	(ABC) transporter
R7A2020_RS26265	COG1132	(ABC) transporter
R7A2020_RS26295	COG1063	alcohol dehydrogenase
R7A2020_RS26300	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
R7A2020_RS26305	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS26310	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
R7A2020_RS26315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
R7A2020_RS26330	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
R7A2020_RS26345	COG0395	ABC-type sugar transport system, permease component
R7A2020_RS26350	COG1175	transmembrane transport
R7A2020_RS26360	COG1802	Transcriptional regulator
R7A2020_RS26380	COG0438	transferase activity, transferring glycosyl groups
R7A2020_RS26385	COG0346	lactoylglutathione lyase activity
R7A2020_RS26390	COG4948	Mandelate Racemase Muconate Lactonizing
R7A2020_RS26395	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS26400	COG1879	ABC-type sugar transport system periplasmic component
R7A2020_RS26405	COG1129	ABC transporter
R7A2020_RS26410	COG1172	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS26415	COG2186	Transcriptional regulator
R7A2020_RS26470	COG1335	isochorismatase
R7A2020_RS26535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
R7A2020_RS26545	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
R7A2020_RS26570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
R7A2020_RS26580	COG1012	belongs to the aldehyde dehydrogenase family
R7A2020_RS26585	COG0473	3-isopropylmalate dehydrogenase activity
R7A2020_RS26590	COG1012	belongs to the aldehyde dehydrogenase family
R7A2020_RS26595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
R7A2020_RS26605	COG0454	-acetyltransferase
R7A2020_RS26630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
R7A2020_RS26640	COG1522	sequence-specific DNA binding
R7A2020_RS26660	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
R7A2020_RS26670	COG0583	DNA-binding transcription factor activity
R7A2020_RS26675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
R7A2020_RS26680	COG1879	ABC-type sugar transport system periplasmic component
R7A2020_RS26685	COG1129	ABC transporter
R7A2020_RS26695	COG0287	Prephenate dehydrogenase
R7A2020_RS26710	COG1129	ABC transporter
R7A2020_RS26715	COG1172	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS26720	COG0673	inositol 2-dehydrogenase activity
R7A2020_RS26735	COG1850	ribulose-bisphosphate carboxylase activity
R7A2020_RS26745	COG3842	ATPase activity
R7A2020_RS26755	COG0395	ABC-type sugar transport system, permease component
R7A2020_RS26760	COG1175	transmembrane transport
R7A2020_RS26770	COG0518	GMP synthase (glutamine-hydrolyzing) activity
R7A2020_RS26770	COG0519	Catalyzes the synthesis of GMP from XMP
R7A2020_RS26775	COG0583	DNA-binding transcription factor activity
R7A2020_RS26785	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS26805	COG0519	Catalyzes the synthesis of GMP from XMP
R7A2020_RS26805	COG0518	GMP synthase (glutamine-hydrolyzing) activity
R7A2020_RS26830	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
R7A2020_RS26830	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
R7A2020_RS26835	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
R7A2020_RS26840	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
R7A2020_RS26845	COG0583	DNA-binding transcription factor activity
R7A2020_RS26870	COG0387	Pfam Sodium calcium exchanger
R7A2020_RS26875	COG0318	PFAM AMP-dependent synthetase and ligase
R7A2020_RS26880	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
R7A2020_RS26885	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
R7A2020_RS26890	COG0124	histidyl-tRNA synthetase
R7A2020_RS26905	COG2818	Glycosylase
R7A2020_RS26910	COG1376	ErfK ybiS ycfS ynhG family protein
R7A2020_RS26915	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
R7A2020_RS26925	COG0247	lactate metabolic process
R7A2020_RS26930	COG0277	FAD linked oxidase domain protein
R7A2020_RS26940	COG0277	FAD linked oxidase domain protein
R7A2020_RS27000	COG0583	DNA-binding transcription factor activity
R7A2020_RS27005	COG1570	exodeoxyribonuclease VII activity
R7A2020_RS27085	COG0277	FAD linked oxidase domain protein
R7A2020_RS27090	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
R7A2020_RS27095	COG1595	DNA-templated transcription, initiation
R7A2020_RS27100	COG1312	Catalyzes the dehydration of D-mannonate
R7A2020_RS27105	COG2186	Transcriptional regulator
R7A2020_RS27110	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS27125	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS27130	COG3769	mannosylglycerate metabolic process
R7A2020_RS27155	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
R7A2020_RS27170	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
R7A2020_RS27175	COG1845	cytochrome c oxidase, subunit III
R7A2020_RS27180	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
R7A2020_RS27185	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
R7A2020_RS27190	COG0477	Major facilitator Superfamily
R7A2020_RS27195	COG2130	NADP-dependent
R7A2020_RS27225	COG2165	general secretion pathway protein
R7A2020_RS27250	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
R7A2020_RS27280	COG3938	Belongs to the proline racemase family
R7A2020_RS27285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
R7A2020_RS27290	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS27295	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
R7A2020_RS27300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
R7A2020_RS27315	COG1129	ABC transporter
R7A2020_RS27335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
R7A2020_RS27340	COG1116	anion transmembrane transporter activity
R7A2020_RS27345	COG1250	3-hydroxyacyl-CoA dehydrogenase
R7A2020_RS27355	COG0235	Class ii aldolase
R7A2020_RS27375	COG2945	thiolester hydrolase activity
R7A2020_RS27375	COG0596	Alpha beta hydrolase
R7A2020_RS27380	COG2188	Transcriptional regulator
R7A2020_RS27410	COG0010	Belongs to the arginase family
R7A2020_RS27420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
R7A2020_RS27430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
R7A2020_RS27435	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
R7A2020_RS27445	COG1596	polysaccharide export
R7A2020_RS27455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
R7A2020_RS27460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
R7A2020_RS27465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
R7A2020_RS27470	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
R7A2020_RS27505	COG0367	asparagine synthase
R7A2020_RS27540	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
R7A2020_RS27540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
R7A2020_RS27545	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
R7A2020_RS27550	COG0367	asparagine synthase
R7A2020_RS27555	COG0318	PFAM AMP-dependent synthetase and ligase
R7A2020_RS27565	COG2890	protein-(glutamine-N5) methyltransferase activity
R7A2020_RS27570	COG0667	Aldo Keto reductase
R7A2020_RS27585	COG0662	Cupin 2, conserved barrel domain protein
R7A2020_RS27600	COG2235	arginine
R7A2020_RS27630	COG0628	permease
R7A2020_RS27655	COG1335	isochorismatase
R7A2020_RS27665	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS27680	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS27705	COG5001	Diguanylate cyclase
R7A2020_RS27715	COG2226	methyltransferase
R7A2020_RS27735	COG1793	dna ligase
R7A2020_RS27760	COG0745	RESPONSE REGULATOR receiver
R7A2020_RS27770	COG5002	protein histidine kinase activity
R7A2020_RS27785	COG0300	oxidoreductase activity
R7A2020_RS27800	COG0596	Alpha beta hydrolase
R7A2020_RS27805	COG0596	Alpha beta hydrolase
R7A2020_RS27815	COG1764	response to oxidative stress
R7A2020_RS27820	COG0745	RESPONSE REGULATOR receiver
R7A2020_RS27830	COG4608	Belongs to the ABC transporter superfamily
R7A2020_RS27835	COG0444	Belongs to the ABC transporter superfamily
R7A2020_RS27840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
R7A2020_RS27845	COG0601	transmembrane transport
R7A2020_RS27855	COG0747	negative chemotaxis
R7A2020_RS27925	COG0395	ABC-type sugar transport system, permease component
R7A2020_RS27935	COG1653	transport
R7A2020_RS27940	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
R7A2020_RS27945	COG0028	Belongs to the TPP enzyme family
R7A2020_RS27960	COG0673	inositol 2-dehydrogenase activity
R7A2020_RS27970	COG0483	inositol monophosphate 1-phosphatase activity
R7A2020_RS27975	COG2223	nitrite transmembrane transporter activity
R7A2020_RS27990	COG1012	belongs to the aldehyde dehydrogenase family
R7A2020_RS28005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
R7A2020_RS28035	COG2010	Cytochrome c
R7A2020_RS28085	COG0745	RESPONSE REGULATOR receiver
R7A2020_RS28120	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
R7A2020_RS28130	COG4191	Histidine kinase
R7A2020_RS28150	COG0156	8-amino-7-oxononanoate synthase activity
R7A2020_RS28185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
R7A2020_RS28185	COG1042	CoA-binding domain protein
R7A2020_RS28185	COG0045	succinate-CoA ligase (ADP-forming) activity
R7A2020_RS28190	COG2217	Heavy metal translocating P-type atpase
R7A2020_RS28195	COG3118	belongs to the thioredoxin family
R7A2020_RS28230	COG0515	serine threonine protein kinase
R7A2020_RS28230	COG2815	serine threonine protein kinase
R7A2020_RS28260	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
R7A2020_RS28265	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
R7A2020_RS28280	COG5490	Phasin protein
R7A2020_RS28285	COG2205	protein histidine kinase activity
R7A2020_RS28290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
R7A2020_RS28300	COG1177	transmembrane transport
R7A2020_RS28305	COG1176	ABC-type spermidine putrescine transport system, permease component I
R7A2020_RS28310	COG3842	ATPase activity
R7A2020_RS28330	COG2224	Isocitrate lyase
R7A2020_RS28350	COG0174	glutamine synthetase
R7A2020_RS28355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
R7A2020_RS28370	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
R7A2020_RS28375	COG0363	glucosamine-6-phosphate deaminase activity
R7A2020_RS28380	COG0129	dihydroxy-acid dehydratase activity
R7A2020_RS28390	COG2304	oxidoreductase activity
R7A2020_RS28400	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
R7A2020_RS28420	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
R7A2020_RS28450	COG2132	Multicopper oxidase
R7A2020_RS28520	COG4964	Belongs to the GSP D family
R7A2020_RS28570	COG2274	protein secretion by the type I secretion system
R7A2020_RS28610	COG3706	GGDEF domain
R7A2020_RS28640	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
R7A2020_RS28650	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
R7A2020_RS28655	COG5328	Belongs to the UPF0262 family
R7A2020_RS28665	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
R7A2020_RS28670	COG0424	maF-like protein
R7A2020_RS28675	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
R7A2020_RS28680	COG1486	melibiose metabolic process
R7A2020_RS28685	COG4172	Belongs to the ABC transporter superfamily
R7A2020_RS28690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
R7A2020_RS28700	COG0747	negative chemotaxis
R7A2020_RS28705	COG1486	melibiose metabolic process
R7A2020_RS28710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
R7A2020_RS28710	COG2207	Transcriptional regulator
R7A2020_RS28740	COG2207	Transcriptional regulator
R7A2020_RS28750	COG0582	viral genome integration into host DNA
R7A2020_RS28820	COG2010	Cytochrome c
R7A2020_RS28850	COG0635	Involved in the biosynthesis of porphyrin-containing compound
R7A2020_RS28860	COG2948	multi-organism process
R7A2020_RS28885	COG3451	type IV secretory pathway VirB4
R7A2020_RS28895	COG3838	Conjugal transfer protein Trbc
R7A2020_RS28900	COG4962	Type ii secretion system protein e
R7A2020_RS28935	COG0635	Involved in the biosynthesis of porphyrin-containing compound
R7A2020_RS28950	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
R7A2020_RS28955	COG3916	Acyl-homoserine-lactone synthase
R7A2020_RS28975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
R7A2020_RS29050	COG0745	RESPONSE REGULATOR receiver
R7A2020_RS29055	COG4372	Transposase
R7A2020_RS29075	COG1278	Cold shock
R7A2020_RS29085	COG1304	FMN binding
R7A2020_RS29095	COG1657	PFAM Prenyltransferase squalene oxidase
R7A2020_RS29100	COG0142	geranyltranstransferase activity
R7A2020_RS29105	COG2124	cytochrome p450
R7A2020_RS29110	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS29115	COG2124	cytochrome p450
R7A2020_RS29120	COG2124	cytochrome p450
R7A2020_RS29145	COG0583	DNA-binding transcription factor activity
R7A2020_RS29150	COG1129	ABC transporter
R7A2020_RS29155	COG1172	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS29160	COG1879	ABC-type sugar transport system periplasmic component
R7A2020_RS29165	COG3618	amidohydrolase
R7A2020_RS29170	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS29175	COG3959	Transketolase, thiamine diphosphate binding domain
R7A2020_RS29180	COG3958	Transketolase
R7A2020_RS29210	COG0464	growth
R7A2020_RS29260	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
R7A2020_RS29300	COG4959	Type IV secretory pathway protease TraF
R7A2020_RS29330	COG0583	DNA-binding transcription factor activity
R7A2020_RS29335	COG3594	Acyltransferase
R7A2020_RS29345	COG0583	DNA-binding transcription factor activity
R7A2020_RS29365	COG0726	polysaccharide deacetylase
R7A2020_RS29385	COG2192	nodulation
R7A2020_RS29395	COG1131	(ABC) transporter
R7A2020_RS29400	COG1215	transferase activity, transferring glycosyl groups
R7A2020_RS29405	COG3153	acetyltransferase
R7A2020_RS29460	COG1525	nuclease
R7A2020_RS29475	COG3591	Belongs to the peptidase S1B family
R7A2020_RS29475	COG1864	DNA RNA non-specific endonuclease
R7A2020_RS29515	COG1475	DNA binding
R7A2020_RS29560	COG3047	cAMP biosynthetic process
R7A2020_RS29575	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
R7A2020_RS29590	COG4957	zinc ion binding
R7A2020_RS29595	COG1278	Cold shock
R7A2020_RS29600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
R7A2020_RS29605	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
R7A2020_RS29610	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
R7A2020_RS29655	COG2197	response regulator
R7A2020_RS29660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
R7A2020_RS29665	COG1522	sequence-specific DNA binding
R7A2020_RS29670	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
R7A2020_RS29670	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
R7A2020_RS29680	COG0583	DNA-binding transcription factor activity
R7A2020_RS29685	COG2301	Belongs to the HpcH HpaI aldolase family
R7A2020_RS29695	COG3799	methylaspartate ammonia-lyase activity
R7A2020_RS29700	COG3608	succinylglutamate desuccinylase aspartoacylase
R7A2020_RS29730	COG2843	Capsule synthesis protein
R7A2020_RS29735	COG4608	Belongs to the ABC transporter superfamily
R7A2020_RS29740	COG0444	Belongs to the ABC transporter superfamily
R7A2020_RS29745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
R7A2020_RS29750	COG0601	transmembrane transport
R7A2020_RS29755	COG0747	negative chemotaxis
R7A2020_RS29765	COG1181	Belongs to the D-alanine--D-alanine ligase family
R7A2020_RS29785	COG0154	amidase activity
R7A2020_RS29795	COG1181	Belongs to the D-alanine--D-alanine ligase family
R7A2020_RS29825	COG0006	proline dipeptidase activity
R7A2020_RS29840	COG0006	proline dipeptidase activity
R7A2020_RS29855	COG2813	Specifically methylates the guanine in position
R7A2020_RS29925	COG4974	Belongs to the 'phage' integrase family
R7A2020_RS29935	COG4974	Belongs to the 'phage' integrase family
R7A2020_RS29950	COG4974	Belongs to the 'phage' integrase family
R7A2020_RS29955	COG0582	viral genome integration into host DNA
R7A2020_RS29960	COG4974	Belongs to the 'phage' integrase family
R7A2020_RS29980	COG1176	ABC-type spermidine putrescine transport system, permease component I
R7A2020_RS29990	COG3842	ATPase activity
R7A2020_RS30000	COG0006	proline dipeptidase activity
R7A2020_RS30030	COG0404	The glycine cleavage system catalyzes the degradation of glycine
R7A2020_RS30030	COG0446	pyridine nucleotide-disulphide oxidoreductase
R7A2020_RS30035	COG4311	Sarcosine oxidase, delta subunit
R7A2020_RS30040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
R7A2020_RS30045	COG4977	sequence-specific DNA binding
R7A2020_RS30060	COG1126	abc transporter atp-binding protein
R7A2020_RS30070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
R7A2020_RS30080	COG0156	8-amino-7-oxononanoate synthase activity
R7A2020_RS30090	COG1522	sequence-specific DNA binding
R7A2020_RS30115	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
R7A2020_RS30135	COG0446	pyridine nucleotide-disulphide oxidoreductase
R7A2020_RS30135	COG0404	The glycine cleavage system catalyzes the degradation of glycine
R7A2020_RS30140	COG4311	Sarcosine oxidase, delta subunit
R7A2020_RS30145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
R7A2020_RS30160	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
R7A2020_RS30170	COG0316	Belongs to the HesB IscA family
R7A2020_RS30185	COG0602	queuosine metabolic process
R7A2020_RS30190	COG0720	synthase
R7A2020_RS30195	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
R7A2020_RS30200	COG1609	Transcriptional regulator
R7A2020_RS30220	COG2515	1-aminocyclopropane-1-carboxylate deaminase
R7A2020_RS30235	COG3383	formate dehydrogenase (NAD+) activity
R7A2020_RS30250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
R7A2020_RS30250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
R7A2020_RS30280	COG4689	acetoacetate decarboxylase
R7A2020_RS30300	COG0745	RESPONSE REGULATOR receiver
R7A2020_RS30310	COG1433	Dinitrogenase iron-molybdenum cofactor
R7A2020_RS30315	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
R7A2020_RS30320	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
R7A2020_RS30325	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
R7A2020_RS30330	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
R7A2020_RS30335	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
R7A2020_RS30360	COG3436	PFAM IS66 Orf2 family protein
R7A2020_RS30365	COG4372	Transposase
R7A2020_RS30390	COG4778	phosphonate C-P lyase system protein PhnL
R7A2020_RS30395	COG3454	Phosphonate metabolism
R7A2020_RS30400	COG4107	phosphonate C-P lyase system protein PhnK
R7A2020_RS30405	COG3627	carbon phosphorus lyase activity
R7A2020_RS30410	COG3626	phosphonate metabolism
R7A2020_RS30420	COG3624	Phosphonate C-P lyase system protein PhnG
R7A2020_RS30435	COG4608	Belongs to the ABC transporter superfamily
R7A2020_RS30440	COG0444	Belongs to the ABC transporter superfamily
R7A2020_RS30445	COG0747	negative chemotaxis
R7A2020_RS30450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
R7A2020_RS30475	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
R7A2020_RS30480	COG0367	asparagine synthase
R7A2020_RS30495	COG1213	nucleotidyl transferase
R7A2020_RS30510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
R7A2020_RS30515	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS30520	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
R7A2020_RS30530	COG2124	cytochrome p450
R7A2020_RS30540	COG0678	peroxiredoxin activity
R7A2020_RS30545	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
R7A2020_RS30555	COG3383	formate dehydrogenase (NAD+) activity
R7A2020_RS30560	COG5420	small protein containing a coiled-coil domain
R7A2020_RS30565	COG5265	(ABC) transporter
R7A2020_RS30575	COG1104	cysteine desulfurase activity
R7A2020_RS30585	COG2086	electron transfer activity
R7A2020_RS30590	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
R7A2020_RS30595	COG0644	oxidoreductase
R7A2020_RS30610	COG0535	radical SAM domain protein
R7A2020_RS30615	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
R7A2020_RS30620	COG5554	nitrogen fixation
R7A2020_RS30625	COG5554	nitrogen fixation
R7A2020_RS30635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
R7A2020_RS30640	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
R7A2020_RS30675	COG2204	response regulator
R7A2020_RS30680	COG4191	Histidine kinase
R7A2020_RS30685	COG1301	dicarboxylic acid transport
R7A2020_RS30700	COG3604	Transcriptional regulator
R7A2020_RS30710	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
R7A2020_RS30715	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
R7A2020_RS30730	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
R7A2020_RS30740	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
R7A2020_RS30745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
R7A2020_RS30750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
R7A2020_RS30755	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
R7A2020_RS30770	COG0459	protein refolding
R7A2020_RS30780	COG1012	belongs to the aldehyde dehydrogenase family
R7A2020_RS30815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
R7A2020_RS30825	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
R7A2020_RS30830	COG0720	synthase
R7A2020_RS30835	COG0602	queuosine metabolic process
R7A2020_RS30840	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
R7A2020_RS30855	COG2022	thiamine diphosphate biosynthetic process
R7A2020_RS30870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
R7A2020_RS30875	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
R7A2020_RS30935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
R7A2020_RS31000	COG1454	alcohol dehydrogenase
R7A2020_RS31035	COG4952	isomerase
R7A2020_RS31040	COG3347	Dehydrogenase
R7A2020_RS31040	COG1028	Short-chain dehydrogenase reductase Sdr
R7A2020_RS31045	COG1349	DNA-binding transcription factor activity
R7A2020_RS31055	COG1129	ABC transporter
R7A2020_RS31060	COG1172	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS31065	COG1172	Belongs to the binding-protein-dependent transport system permease family
R7A2020_RS31070	COG3254	rhamnose metabolic process
R7A2020_RS31075	COG1070	Carbohydrate kinase
R7A2020_RS31080	COG3457	Alanine racemase
R7A2020_RS31085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
R7A2020_RS31095	COG0156	8-amino-7-oxononanoate synthase activity
R7A2020_RS31100	COG0436	Aminotransferase
R7A2020_RS31105	COG1970	mechanosensitive ion channel activity
R7A2020_RS31110	COG2205	protein histidine kinase activity
R7A2020_RS31110	COG0784	Response regulator, receiver
R7A2020_RS31130	COG0583	DNA-binding transcription factor activity
R7A2020_RS31135	COG0477	Major facilitator Superfamily
R7A2020_RS31155	COG0167	dihydroorotate dehydrogenase activity
R7A2020_RS31160	COG0534	Mate efflux family protein
R7A2020_RS31165	COG0123	including yeast histone deacetylase and acetoin utilization protein
R7A2020_RS31185	COG0745	RESPONSE REGULATOR receiver
R7A2020_RS31190	COG0642	Histidine kinase
R7A2020_RS31195	COG0463	Glycosyl transferase, family 2
R7A2020_RS31235	COG1129	ABC transporter
R7A2020_RS31240	COG4214	carbohydrate transport
R7A2020_RS31250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
R7A2020_RS31255	COG0717	Belongs to the dCTP deaminase family
R7A2020_RS31270	COG2967	ApaG domain
R7A2020_RS31280	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
R7A2020_RS31285	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
R7A2020_RS31295	COG0598	Magnesium transport protein CorA
R7A2020_RS31300	COG0704	Plays a role in the regulation of phosphate uptake
R7A2020_RS31305	COG5002	protein histidine kinase activity
R7A2020_RS31310	COG2326	polyphosphate kinase activity
R7A2020_RS31315	COG1024	Enoyl-CoA hydratase
R7A2020_RS31325	COG2197	response regulator
R7A2020_RS31330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
R7A2020_RS31340	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
R7A2020_RS31360	COG1024	Enoyl-CoA hydratase
R7A2020_RS31360	COG1250	3-hydroxyacyl-CoA dehydrogenase
R7A2020_RS31365	COG0183	Belongs to the thiolase family
R7A2020_RS31370	COG1960	acyl-CoA dehydrogenase activity
R7A2020_RS31375	COG1960	acyl-CoA dehydrogenase activity
R7A2020_RS31380	COG0789	Transcriptional regulator
R7A2020_RS31390	COG0730	response to heat
R7A2020_RS31400	COG0443	Heat shock 70 kDa protein
R7A2020_RS31410	COG0243	molybdopterin cofactor binding
R7A2020_RS31415	COG0437	4 iron, 4 sulfur cluster binding
R7A2020_RS31420	COG3302	dmso reductase anchor subunit
R7A2020_RS31435	COG1201	RNA secondary structure unwinding
R7A2020_RS31440	COG0791	NLP P60 protein
R7A2020_RS31450	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
R7A2020_RS31485	COG4964	Belongs to the GSP D family
R7A2020_RS31525	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
R7A2020_RS31530	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
R7A2020_RS31535	COG1024	Enoyl-CoA hydratase
R7A2020_RS31540	COG0268	Binds directly to 16S ribosomal RNA