locus-tag	class	description
JN280_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JN280_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JN280_RS00025	COG0456	acetyltransferase
JN280_RS00040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JN280_RS00055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JN280_RS00065	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JN280_RS00070	COG5001	Diguanylate cyclase
JN280_RS00070	COG3300	MHYT domain
JN280_RS00080	COG1185	polyribonucleotide nucleotidyltransferase activity
JN280_RS00085	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JN280_RS00090	COG0598	Magnesium transport protein CorA
JN280_RS00095	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JN280_RS00100	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JN280_RS00105	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JN280_RS00120	COG0779	Required for maturation of 30S ribosomal subunits
JN280_RS00155	COG0713	ATP synthesis coupled electron transport
JN280_RS00160	COG0651	ATP synthesis coupled electron transport
JN280_RS00170	COG0651	ATP synthesis coupled electron transport
JN280_RS00190	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JN280_RS00195	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JN280_RS00200	COG0649	NAD binding
JN280_RS00230	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JN280_RS00235	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JN280_RS00240	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JN280_RS00245	COG1396	sequence-specific DNA binding
JN280_RS00250	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JN280_RS00255	COG1253	flavin adenine dinucleotide binding
JN280_RS00260	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JN280_RS00265	COG1702	phosphate starvation-inducible protein PhoH
JN280_RS00270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JN280_RS00285	COG1214	PFAM Peptidase M22, glycoprotease
JN280_RS00290	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JN280_RS00305	COG0583	DNA-binding transcription factor activity
JN280_RS00320	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JN280_RS00330	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JN280_RS00340	COG1609	Transcriptional regulator
JN280_RS00345	COG0402	S-adenosylhomocysteine deaminase activity
JN280_RS00360	COG3845	ABC transporter
JN280_RS00365	COG4603	Belongs to the binding-protein-dependent transport system permease family
JN280_RS00375	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JN280_RS00380	COG0450	alkyl hydroperoxide reductase
JN280_RS00410	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JN280_RS00415	COG2226	methyltransferase
JN280_RS00420	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JN280_RS00425	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JN280_RS00440	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JN280_RS00460	COG1079	Belongs to the binding-protein-dependent transport system permease family
JN280_RS00465	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS00470	COG3845	ABC transporter
JN280_RS00475	COG2900	Belongs to the SlyX family
JN280_RS00490	COG1744	ABC transporter substrate-binding protein PnrA-like
JN280_RS00510	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JN280_RS00510	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JN280_RS00530	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JN280_RS00545	COG1175	transmembrane transport
JN280_RS00550	COG0395	ABC-type sugar transport system, permease component
JN280_RS00555	COG1609	Transcriptional regulator
JN280_RS00565	COG3842	ATPase activity
JN280_RS00590	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JN280_RS00595	COG1250	3-hydroxyacyl-CoA dehydrogenase
JN280_RS00595	COG1024	Enoyl-CoA hydratase
JN280_RS00600	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JN280_RS00640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JN280_RS00650	COG2271	Major facilitator Superfamily
JN280_RS00655	COG3608	succinylglutamate desuccinylase aspartoacylase
JN280_RS00660	COG0006	proline dipeptidase activity
JN280_RS00665	COG2423	ornithine cyclodeaminase activity
JN280_RS00670	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JN280_RS00680	COG0765	amino acid transport
JN280_RS00685	COG0765	amino acid transport
JN280_RS00695	COG1126	abc transporter atp-binding protein
JN280_RS00700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JN280_RS00705	COG1522	sequence-specific DNA binding
JN280_RS00710	COG1012	belongs to the aldehyde dehydrogenase family
JN280_RS00715	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JN280_RS00735	COG0395	ABC-type sugar transport system, permease component
JN280_RS00740	COG0346	lactoylglutathione lyase activity
JN280_RS00755	COG0559	Belongs to the binding-protein-dependent transport system permease family
JN280_RS00765	COG1022	Amp-dependent synthetase and ligase
JN280_RS00780	COG1024	Enoyl-CoA hydratase
JN280_RS00785	COG1309	transcriptional regulator
JN280_RS00790	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS00805	COG0183	Belongs to the thiolase family
JN280_RS00810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JN280_RS00820	COG1126	abc transporter atp-binding protein
JN280_RS00825	COG0765	amino acid transport
JN280_RS00830	COG0765	amino acid transport
JN280_RS00855	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS00870	COG2273	Hydrolase Family 16
JN280_RS00870	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
JN280_RS00880	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
JN280_RS00880	COG2273	Hydrolase Family 16
JN280_RS00895	COG1120	ATPase activity
JN280_RS00900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JN280_RS00910	COG4206	TonB-dependent receptor
JN280_RS00915	COG2186	Transcriptional regulator
JN280_RS00935	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS00940	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JN280_RS00940	COG0473	3-isopropylmalate dehydrogenase activity
JN280_RS00945	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JN280_RS00950	COG2764	glyoxalase bleomycin resistance protein dioxygenase
JN280_RS00970	COG0625	glutathione transferase activity
JN280_RS00985	COG3734	2-keto-3-deoxy-galactonokinase
JN280_RS00990	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JN280_RS01000	COG1129	ABC transporter
JN280_RS01005	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS01020	COG3347	Dehydrogenase
JN280_RS01020	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS01030	COG0667	Aldo Keto reductase
JN280_RS01075	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS01085	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JN280_RS01090	COG1917	Cupin 2, conserved barrel domain protein
JN280_RS01090	COG1396	sequence-specific DNA binding
JN280_RS01100	COG3842	ATPase activity
JN280_RS01105	COG1176	ABC-type spermidine putrescine transport system, permease component I
JN280_RS01110	COG1177	transmembrane transport
JN280_RS01115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JN280_RS01145	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
JN280_RS01150	COG3454	Phosphonate metabolism
JN280_RS01155	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
JN280_RS01160	COG3639	organic phosphonate transmembrane transporter activity
JN280_RS01175	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
JN280_RS01195	COG4778	phosphonate C-P lyase system protein PhnL
JN280_RS01205	COG4107	phosphonate C-P lyase system protein PhnK
JN280_RS01210	COG3627	carbon phosphorus lyase activity
JN280_RS01215	COG3626	phosphonate metabolism
JN280_RS01220	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
JN280_RS01225	COG3624	Phosphonate C-P lyase system protein PhnG
JN280_RS01230	COG2188	Transcriptional regulator
JN280_RS01235	COG4134	Bacterial extracellular solute-binding protein
JN280_RS01240	COG4135	transport system, permease component
JN280_RS01245	COG4136	ATPase activity
JN280_RS01250	COG1643	Atp-dependent helicase
JN280_RS01260	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
JN280_RS01270	COG1388	LysM domain
JN280_RS01270	COG1376	ErfK ybiS ycfS ynhG family protein
JN280_RS01275	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JN280_RS01285	COG0180	Tryptophanyl-tRNA synthetase
JN280_RS01290	COG0728	peptidoglycan biosynthetic process
JN280_RS01295	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
JN280_RS01300	COG0443	Heat shock 70 kDa protein
JN280_RS01305	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JN280_RS01310	COG0281	malic enzyme
JN280_RS01310	COG0280	phosphate acetyltransferase
JN280_RS01315	COG5001	Diguanylate cyclase
JN280_RS01330	COG0583	DNA-binding transcription factor activity
JN280_RS01335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN280_RS01345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JN280_RS01350	COG4774	siderophore transport
JN280_RS01355	COG2814	Major facilitator Superfamily
JN280_RS01375	COG2226	methyltransferase
JN280_RS01390	COG2205	protein histidine kinase activity
JN280_RS01390	COG5002	protein histidine kinase activity
JN280_RS01390	COG0784	Response regulator, receiver
JN280_RS01395	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JN280_RS01400	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JN280_RS01405	COG0116	Belongs to the methyltransferase superfamily
JN280_RS01405	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JN280_RS01415	COG2423	ornithine cyclodeaminase activity
JN280_RS01425	COG0776	regulation of translation
JN280_RS01430	COG0616	signal peptide processing
JN280_RS01440	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
JN280_RS01445	COG1137	ATPase activity
JN280_RS01450	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JN280_RS01455	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JN280_RS01460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JN280_RS01470	COG0071	Belongs to the small heat shock protein (HSP20) family
JN280_RS01490	COG3033	Beta-eliminating lyase
JN280_RS01500	COG1280	lysine exporter protein (LysE YggA)
JN280_RS01505	COG0154	amidase activity
JN280_RS01510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JN280_RS01545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JN280_RS01550	COG2860	membrane
JN280_RS01555	COG0456	acetyltransferase
JN280_RS01560	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JN280_RS01570	COG1420	regulation of RNA biosynthetic process
JN280_RS01585	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JN280_RS01595	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JN280_RS01600	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JN280_RS01615	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JN280_RS01620	COG0792	nuclease activity
JN280_RS01625	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
JN280_RS01630	COG2124	cytochrome p450
JN280_RS01640	COG0673	inositol 2-dehydrogenase activity
JN280_RS01680	COG2175	clavaminate synthase activity
JN280_RS01685	COG3246	L-lysine catabolic process to acetate
JN280_RS01715	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JN280_RS01715	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JN280_RS01735	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JN280_RS01740	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JN280_RS01750	COG4191	Histidine kinase
JN280_RS01755	COG4566	intracellular signal transduction
JN280_RS01760	COG3119	arylsulfatase activity
JN280_RS01770	COG0714	Associated with various cellular activities
JN280_RS01800	COG4566	intracellular signal transduction
JN280_RS01825	COG1116	anion transmembrane transporter activity
JN280_RS01830	COG0010	Belongs to the arginase family
JN280_RS01855	COG0156	8-amino-7-oxononanoate synthase activity
JN280_RS01860	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JN280_RS01865	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JN280_RS01870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JN280_RS01885	COG1053	succinate dehydrogenase
JN280_RS01910	COG0066	3-isopropylmalate dehydratase activity
JN280_RS01915	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JN280_RS01945	COG2188	Transcriptional regulator
JN280_RS01955	COG0583	DNA-binding transcription factor activity
JN280_RS01965	COG3842	ATPase activity
JN280_RS01975	COG1176	ABC-type spermidine putrescine transport system, permease component I
JN280_RS01995	COG0508	dehydrogenase complex catalyzes the overall conversion of
JN280_RS02000	COG0022	dehydrogenase e1 component
JN280_RS02005	COG1522	sequence-specific DNA binding
JN280_RS02040	COG2030	dehydratase
JN280_RS02040	COG1012	belongs to the aldehyde dehydrogenase family
JN280_RS02045	COG1024	Enoyl-CoA hydratase
JN280_RS02050	COG2050	protein possibly involved in aromatic compounds catabolism
JN280_RS02060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JN280_RS02065	COG2151	metal-sulfur cluster biosynthetic enzyme
JN280_RS02070	COG3396	Phenylacetate-CoA oxygenase
JN280_RS02075	COG3460	Phenylacetate-CoA oxygenase
JN280_RS02080	COG3396	Phenylacetate-CoA oxygenase
JN280_RS02085	COG3327	negative regulation of DNA-templated transcription, initiation
JN280_RS02100	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JN280_RS02115	COG1733	regulation of RNA biosynthetic process
JN280_RS02135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JN280_RS02195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JN280_RS02205	COG0583	DNA-binding transcription factor activity
JN280_RS02220	COG1012	belongs to the aldehyde dehydrogenase family
JN280_RS02235	COG5441	Belongs to the UPF0261 family
JN280_RS02260	COG4213	ABC transporter substrate-binding protein
JN280_RS02265	COG1129	ABC transporter
JN280_RS02270	COG4214	carbohydrate transport
JN280_RS02280	COG0129	dihydroxy-acid dehydratase activity
JN280_RS02290	COG0640	Transcriptional regulator
JN280_RS02320	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JN280_RS02325	COG1216	Glycosyl transferase, family 2
JN280_RS02325	COG0463	Glycosyl transferase, family 2
JN280_RS02330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN280_RS02340	COG0583	DNA-binding transcription factor activity
JN280_RS02345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN280_RS02350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JN280_RS02355	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JN280_RS02370	COG0534	Mate efflux family protein
JN280_RS02385	COG2267	carboxylic ester hydrolase activity
JN280_RS02405	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JN280_RS02415	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JN280_RS02420	COG3473	Maleate cis-trans isomerase
JN280_RS02425	COG0824	Thioesterase
JN280_RS02445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JN280_RS02450	COG1178	ABC-type Fe3 transport system permease component
JN280_RS02455	COG1176	ABC-type spermidine putrescine transport system, permease component I
JN280_RS02460	COG3842	ATPase activity
JN280_RS02475	COG0583	DNA-binding transcription factor activity
JN280_RS02480	COG1454	alcohol dehydrogenase
JN280_RS02495	COG3077	Addiction module antitoxin, RelB DinJ family
JN280_RS02505	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JN280_RS02545	COG1335	isochorismatase
JN280_RS02575	COG1846	Transcriptional regulator
JN280_RS02615	COG0625	glutathione transferase activity
JN280_RS02620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JN280_RS02625	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
JN280_RS02630	COG1448	Aminotransferase
JN280_RS02635	COG2111	Na H antiporter
JN280_RS02635	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JN280_RS02640	COG1006	Multisubunit Na H antiporter MnhC subunit
JN280_RS02645	COG0651	ATP synthesis coupled electron transport
JN280_RS02650	COG1863	multisubunit Na H antiporter MnhE subunit
JN280_RS02655	COG2212	antiporter activity
JN280_RS02660	COG1320	monovalent cation:proton antiporter activity
JN280_RS02670	COG2080	2 iron, 2 sulfur cluster binding
JN280_RS02675	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JN280_RS02680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JN280_RS02700	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JN280_RS02715	COG3384	dioxygenase
JN280_RS02720	COG1414	Transcriptional regulator
JN280_RS02730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN280_RS02765	COG3842	ATPase activity
JN280_RS02775	COG2081	HI0933 family
JN280_RS02785	COG0395	ABC-type sugar transport system, permease component
JN280_RS02790	COG1175	transmembrane transport
JN280_RS02805	COG0617	tRNA 3'-terminal CCA addition
JN280_RS02805	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JN280_RS02805	COG0517	IMP dehydrogenase activity
JN280_RS02830	COG0175	sulfate reduction
JN280_RS02835	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JN280_RS02845	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JN280_RS02845	COG1648	precorrin-2 dehydrogenase activity
JN280_RS02875	COG1137	ATPase activity
JN280_RS02890	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS02895	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JN280_RS02900	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JN280_RS02905	COG2273	Hydrolase Family 16
JN280_RS02905	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
JN280_RS02945	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JN280_RS02960	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JN280_RS02960	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JN280_RS02975	COG2274	protein secretion by the type I secretion system
JN280_RS03015	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
JN280_RS03025	COG0667	Aldo Keto reductase
JN280_RS03045	COG0395	ABC-type sugar transport system, permease component
JN280_RS03050	COG1175	transmembrane transport
JN280_RS03065	COG1609	Transcriptional regulator
JN280_RS03090	COG2186	Transcriptional regulator
JN280_RS03105	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JN280_RS03110	COG1904	glucuronate isomerase
JN280_RS03130	COG0583	DNA-binding transcription factor activity
JN280_RS03135	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS03150	COG3220	belongs to the UPF0276 family
JN280_RS03170	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JN280_RS03190	COG1121	(ABC) transporter
JN280_RS03195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JN280_RS03200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JN280_RS03205	COG1846	Transcriptional regulator
JN280_RS03220	COG1070	Carbohydrate kinase
JN280_RS03225	COG1830	Aldolase
JN280_RS03230	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JN280_RS03235	COG0667	Aldo Keto reductase
JN280_RS03240	COG2390	Transcriptional regulator
JN280_RS03245	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS03250	COG1129	ABC transporter
JN280_RS03260	COG0745	RESPONSE REGULATOR receiver
JN280_RS03270	COG2205	protein histidine kinase activity
JN280_RS03270	COG2202	Pas domain
JN280_RS03295	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JN280_RS03300	COG3842	ATPase activity
JN280_RS03305	COG1176	ABC-type spermidine putrescine transport system, permease component I
JN280_RS03310	COG1177	transmembrane transport
JN280_RS03315	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JN280_RS03320	COG0154	amidase activity
JN280_RS03330	COG4456	Virulence-associated protein
JN280_RS03345	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JN280_RS03350	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JN280_RS03355	COG2188	Transcriptional regulator
JN280_RS03360	COG2971	BadF BadG BcrA BcrD
JN280_RS03370	COG1175	transmembrane transport
JN280_RS03375	COG0395	ABC-type sugar transport system, permease component
JN280_RS03380	COG0673	inositol 2-dehydrogenase activity
JN280_RS03390	COG0179	Fumarylacetoacetate (FAA) hydrolase
JN280_RS03395	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS03400	COG1012	belongs to the aldehyde dehydrogenase family
JN280_RS03405	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JN280_RS03440	COG4598	ABC transporter
JN280_RS03445	COG0765	amino acid transport
JN280_RS03450	COG0765	amino acid transport
JN280_RS03460	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JN280_RS03465	COG1802	Transcriptional regulator
JN280_RS03470	COG1072	(Pantothenic acid kinase))
JN280_RS03480	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JN280_RS03485	COG1686	Belongs to the peptidase S11 family
JN280_RS03520	COG1819	glycosyl
JN280_RS03540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN280_RS03550	COG4191	Histidine kinase
JN280_RS03555	COG4566	intracellular signal transduction
JN280_RS03580	COG1309	transcriptional regulator
JN280_RS03605	COG4191	Histidine kinase
JN280_RS03610	COG4566	intracellular signal transduction
JN280_RS03615	COG2204	response regulator
JN280_RS03620	COG4566	intracellular signal transduction
JN280_RS03630	COG0625	glutathione transferase activity
JN280_RS03665	COG4191	Histidine kinase
JN280_RS03675	COG4566	intracellular signal transduction
JN280_RS03685	COG4191	Histidine kinase
JN280_RS03695	COG3328	transposase activity
JN280_RS03710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JN280_RS03715	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JN280_RS03720	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JN280_RS03735	COG3321	synthase
JN280_RS03735	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS03735	COG0604	alcohol dehydrogenase
JN280_RS03750	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JN280_RS03760	COG0596	Alpha beta hydrolase
JN280_RS03780	COG1309	transcriptional regulator
JN280_RS03790	COG0431	NADPH-dependent FMN reductase
JN280_RS03825	COG4566	intracellular signal transduction
JN280_RS03830	COG4566	intracellular signal transduction
JN280_RS03840	COG4191	Histidine kinase
JN280_RS03845	COG0596	Alpha beta hydrolase
JN280_RS03875	COG0284	orotidine-5'-phosphate decarboxylase activity
JN280_RS03900	COG0418	dihydroorotase activity
JN280_RS03905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JN280_RS03910	COG0167	dihydroorotate dehydrogenase activity
JN280_RS03915	COG0543	2 iron, 2 sulfur cluster binding
JN280_RS03920	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JN280_RS03935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JN280_RS03945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN280_RS03960	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JN280_RS03970	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JN280_RS03980	COG0583	DNA-binding transcription factor activity
JN280_RS04000	COG1522	sequence-specific DNA binding
JN280_RS04020	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS04055	COG1271	oxidase subunit
JN280_RS04060	COG1294	oxidase, subunit
JN280_RS04070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JN280_RS04085	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS04105	COG0434	BtpA family
JN280_RS04130	COG1940	carbohydrate kinase activity
JN280_RS04135	COG0395	ABC-type sugar transport system, permease component
JN280_RS04140	COG1175	transmembrane transport
JN280_RS04150	COG1569	PIN domain
JN280_RS04155	COG3311	Transcriptional regulator
JN280_RS04160	COG0596	Alpha beta hydrolase
JN280_RS04200	COG0010	Belongs to the arginase family
JN280_RS04210	COG2226	methyltransferase
JN280_RS04220	COG1280	lysine exporter protein (LysE YggA)
JN280_RS04225	COG1522	sequence-specific DNA binding
JN280_RS04230	COG1312	Catalyzes the dehydration of D-mannonate
JN280_RS04235	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JN280_RS04235	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JN280_RS04240	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JN280_RS04240	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JN280_RS04245	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JN280_RS04250	COG1802	Transcriptional regulator
JN280_RS04275	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS04290	COG1960	acyl-CoA dehydrogenase activity
JN280_RS04300	COG1024	Enoyl-CoA hydratase
JN280_RS04305	COG3181	Tripartite tricarboxylate transporter family receptor
JN280_RS04310	COG1309	transcriptional regulator
JN280_RS04325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN280_RS04340	COG1960	acyl-CoA dehydrogenase activity
JN280_RS04355	COG0243	molybdopterin cofactor binding
JN280_RS04365	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JN280_RS04375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JN280_RS04380	COG3707	response regulator
JN280_RS04385	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JN280_RS04390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JN280_RS04395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JN280_RS04400	COG4774	siderophore transport
JN280_RS04405	COG1120	ATPase activity
JN280_RS04410	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JN280_RS04420	COG4150	thiosulfate binding
JN280_RS04425	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
JN280_RS04430	COG4208	sulfate ABC transporter
JN280_RS04435	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JN280_RS04465	COG1802	Transcriptional regulator
JN280_RS04475	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JN280_RS04480	COG4120	Belongs to the binding-protein-dependent transport system permease family
JN280_RS04510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JN280_RS04520	COG2205	protein histidine kinase activity
JN280_RS04525	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JN280_RS04530	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JN280_RS04540	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JN280_RS04555	COG0765	amino acid transport
JN280_RS04560	COG0765	amino acid transport
JN280_RS04565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN280_RS04575	COG1879	ABC-type sugar transport system periplasmic component
JN280_RS04580	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS04585	COG1129	ABC transporter
JN280_RS04590	COG2186	Transcriptional regulator
JN280_RS04595	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS04630	COG0395	ABC-type sugar transport system, permease component
JN280_RS04635	COG3842	ATPase activity
JN280_RS04640	COG0251	oxidation-reduction process
JN280_RS04690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN280_RS04695	COG0601	transmembrane transport
JN280_RS04700	COG4166	transmembrane transport
JN280_RS04725	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS04730	COG0596	Alpha beta hydrolase
JN280_RS04760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JN280_RS04840	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JN280_RS04845	COG1653	transport
JN280_RS04850	COG1175	transmembrane transport
JN280_RS04865	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JN280_RS04870	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JN280_RS04875	COG1845	cytochrome c oxidase, subunit III
JN280_RS04880	COG1845	cytochrome c oxidase, subunit III
JN280_RS04895	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JN280_RS04915	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JN280_RS04930	COG0154	amidase activity
JN280_RS04955	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JN280_RS04960	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JN280_RS04965	COG0539	negative regulation of cytoplasmic translation
JN280_RS04980	COG0702	epimerase
JN280_RS04995	COG1175	transmembrane transport
JN280_RS05000	COG0395	ABC-type sugar transport system, permease component
JN280_RS05010	COG3842	ATPase activity
JN280_RS05020	COG4948	Mandelate Racemase Muconate Lactonizing
JN280_RS05045	COG3300	MHYT domain
JN280_RS05045	COG5001	Diguanylate cyclase
JN280_RS05050	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JN280_RS05100	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JN280_RS05115	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS05120	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JN280_RS05130	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JN280_RS05160	COG0154	amidase activity
JN280_RS05170	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS05180	COG1177	transmembrane transport
JN280_RS05185	COG1176	ABC-type spermidine putrescine transport system, permease component I
JN280_RS05190	COG3842	ATPase activity
JN280_RS05195	COG1840	ABC-type Fe3 transport system, periplasmic component
JN280_RS05210	COG1012	belongs to the aldehyde dehydrogenase family
JN280_RS05225	COG2390	Transcriptional regulator
JN280_RS05250	COG1968	undecaprenyl-diphosphatase activity
JN280_RS05260	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JN280_RS05270	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
JN280_RS05275	COG1803	Methylglyoxal synthase
JN280_RS05280	COG0837	glucose binding
JN280_RS05285	COG1132	(ABC) transporter
JN280_RS05290	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JN280_RS05295	COG0588	phosphoglycerate mutase activity
JN280_RS05310	COG1396	sequence-specific DNA binding
JN280_RS05320	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JN280_RS05330	COG3386	PFAM SMP-30 Gluconolaconase
JN280_RS05335	COG0800	Aldolase
JN280_RS05340	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS05345	COG3300	MHYT domain
JN280_RS05345	COG5001	Diguanylate cyclase
JN280_RS05365	COG2076	Multidrug Resistance protein
JN280_RS05370	COG0189	ligase activity
JN280_RS05380	COG0606	chelatase, subunit chli
JN280_RS05410	COG0284	orotidine-5'-phosphate decarboxylase activity
JN280_RS05420	COG3963	phosphatidate phosphatase activity
JN280_RS05425	COG0484	heat shock protein binding
JN280_RS05430	COG0443	Heat shock 70 kDa protein
JN280_RS05435	COG0501	Belongs to the peptidase M48B family
JN280_RS05445	COG1376	ErfK ybiS ycfS ynhG family protein
JN280_RS05460	COG0850	regulation of cytokinetic process
JN280_RS05465	COG2894	cell division
JN280_RS05470	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
JN280_RS05480	COG3038	cytochrome b561
JN280_RS05485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JN280_RS05485	COG0072	phenylalanine-tRNA ligase activity
JN280_RS05500	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JN280_RS05505	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JN280_RS05510	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JN280_RS05515	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JN280_RS05525	COG3135	benzoate transporter
JN280_RS05540	COG0135	phosphoribosylanthranilate isomerase activity
JN280_RS05545	COG0133	tryptophan synthase activity
JN280_RS05550	COG0159	tryptophan synthase activity
JN280_RS05555	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JN280_RS05575	COG1074	ATP-dependent DNA helicase activity
JN280_RS05580	COG2887	Belongs to the helicase family. UvrD subfamily
JN280_RS05585	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JN280_RS05590	COG3178	'Phosphotransferase
JN280_RS05595	COG2205	protein histidine kinase activity
JN280_RS05600	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JN280_RS05610	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JN280_RS05610	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JN280_RS05615	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JN280_RS05620	COG2205	protein histidine kinase activity
JN280_RS05625	COG0745	RESPONSE REGULATOR receiver
JN280_RS05630	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JN280_RS05650	COG1652	LysM domain
JN280_RS05660	COG1072	(Pantothenic acid kinase))
JN280_RS05665	COG0140	phosphoribosyl-ATP diphosphatase activity
JN280_RS05670	COG0107	imidazoleglycerol-phosphate synthase activity
JN280_RS05680	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JN280_RS05685	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JN280_RS05695	COG0131	Imidazoleglycerol-phosphate dehydratase
JN280_RS05700	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JN280_RS05710	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JN280_RS05720	COG1396	sequence-specific DNA binding
JN280_RS05740	COG3030	protein affecting phage T7 exclusion by the F plasmid
JN280_RS05745	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JN280_RS05760	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
JN280_RS05765	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JN280_RS05770	COG0237	dephospho-CoA kinase activity
JN280_RS05775	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JN280_RS05780	COG0424	maF-like protein
JN280_RS05785	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JN280_RS05790	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JN280_RS05795	COG1981	membrane
JN280_RS05800	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JN280_RS05805	COG1331	Highly conserved protein containing a thioredoxin domain
JN280_RS05810	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JN280_RS05815	COG0445	tRNA wobble uridine modification
JN280_RS05820	COG0357	Ribosomal RNA small subunit methyltransferase G
JN280_RS05850	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JN280_RS05855	COG2192	nodulation
JN280_RS05865	COG0668	transmembrane transport
JN280_RS05875	COG4166	transmembrane transport
JN280_RS05880	COG0601	transmembrane transport
JN280_RS05885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN280_RS05895	COG0444	Belongs to the ABC transporter superfamily
JN280_RS05900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN280_RS05905	COG0601	transmembrane transport
JN280_RS05910	COG0747	negative chemotaxis
JN280_RS05925	COG1473	amidohydrolase
JN280_RS05930	COG1473	amidohydrolase
JN280_RS05940	COG0438	transferase activity, transferring glycosyl groups
JN280_RS05970	COG3618	amidohydrolase
JN280_RS05980	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JN280_RS06015	COG0154	amidase activity
JN280_RS06020	COG1609	Transcriptional regulator
JN280_RS06025	COG0601	transmembrane transport
JN280_RS06030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN280_RS06035	COG0444	Belongs to the ABC transporter superfamily
JN280_RS06040	COG4608	Belongs to the ABC transporter superfamily
JN280_RS06045	COG0747	negative chemotaxis
JN280_RS06055	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS06065	COG4821	SIS domain
JN280_RS06070	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
JN280_RS06085	COG1079	Belongs to the binding-protein-dependent transport system permease family
JN280_RS06090	COG4603	Belongs to the binding-protein-dependent transport system permease family
JN280_RS06095	COG3845	ABC transporter
JN280_RS06100	COG1744	ABC transporter substrate-binding protein PnrA-like
JN280_RS06105	COG2188	Transcriptional regulator
JN280_RS06110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JN280_RS06115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JN280_RS06125	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JN280_RS06130	COG0287	Prephenate dehydrogenase
JN280_RS06130	COG1605	Chorismate mutase
JN280_RS06145	COG3300	MHYT domain
JN280_RS06145	COG5001	Diguanylate cyclase
JN280_RS06155	COG0126	phosphoglycerate kinase activity
JN280_RS06160	COG3588	fructose-bisphosphate aldolase
JN280_RS06250	COG0667	Aldo Keto reductase
JN280_RS06255	COG0583	DNA-binding transcription factor activity
JN280_RS06295	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS06305	COG0596	Alpha beta hydrolase
JN280_RS06310	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JN280_RS06355	COG1116	anion transmembrane transporter activity
JN280_RS06360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JN280_RS06395	COG0583	DNA-binding transcription factor activity
JN280_RS06415	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS06460	COG1335	isochorismatase
JN280_RS06470	COG1879	ABC-type sugar transport system periplasmic component
JN280_RS06475	COG1129	ABC transporter
JN280_RS06485	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS06490	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS06515	COG1129	ABC transporter
JN280_RS06520	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS06525	COG0145	ligase activity
JN280_RS06535	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS06545	COG0583	DNA-binding transcription factor activity
JN280_RS06550	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JN280_RS06620	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS06640	COG1960	acyl-CoA dehydrogenase activity
JN280_RS06645	COG1960	acyl-CoA dehydrogenase activity
JN280_RS06650	COG1024	Enoyl-CoA hydratase
JN280_RS06660	COG1024	Enoyl-CoA hydratase
JN280_RS06675	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS06680	COG1960	acyl-CoA dehydrogenase activity
JN280_RS06690	COG0183	Belongs to the thiolase family
JN280_RS06700	COG2130	NADP-dependent
JN280_RS06715	COG0640	Transcriptional regulator
JN280_RS06725	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JN280_RS06730	COG0505	Belongs to the CarA family
JN280_RS06775	COG0138	bifunctional purine biosynthesis protein purh
JN280_RS06795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JN280_RS06800	COG5425	PFAM Usg family protein
JN280_RS06805	COG0667	Aldo Keto reductase
JN280_RS06810	COG2814	Major facilitator Superfamily
JN280_RS06815	COG0583	DNA-binding transcription factor activity
JN280_RS06820	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JN280_RS06825	COG0495	leucyl-tRNA aminoacylation
JN280_RS06840	COG3971	2-oxopent-4-enoate hydratase activity
JN280_RS06865	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JN280_RS06870	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JN280_RS06875	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JN280_RS06880	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JN280_RS06885	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JN280_RS06890	COG1994	Peptidase M50
JN280_RS06895	COG0656	L-ascorbic acid biosynthetic process
JN280_RS06925	COG0494	nUDIX hydrolase
JN280_RS06935	COG0793	Belongs to the peptidase S41A family
JN280_RS06945	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JN280_RS06950	COG0799	negative regulation of ribosome biogenesis
JN280_RS06970	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JN280_RS07010	COG0625	glutathione transferase activity
JN280_RS07025	COG3485	protocatechuate 3,4-dioxygenase
JN280_RS07040	COG0583	DNA-binding transcription factor activity
JN280_RS07045	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JN280_RS07050	COG0196	riboflavin kinase activity
JN280_RS07075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JN280_RS07080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JN280_RS07095	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
JN280_RS07100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN280_RS07105	COG0445	tRNA wobble uridine modification
JN280_RS07115	COG1024	Enoyl-CoA hydratase
JN280_RS07125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JN280_RS07135	COG2226	methyltransferase
JN280_RS07140	COG0339	signal peptide processing
JN280_RS07150	COG2814	Major facilitator Superfamily
JN280_RS07155	COG0288	reversible hydration of carbon dioxide
JN280_RS07160	COG1765	OsmC-like protein
JN280_RS07170	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
JN280_RS07180	COG1704	LemA family
JN280_RS07205	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JN280_RS07210	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
JN280_RS07215	COG0183	Belongs to the thiolase family
JN280_RS07220	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS07225	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JN280_RS07240	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JN280_RS07245	COG1329	Transcriptional regulator
JN280_RS07255	COG1960	acyl-CoA dehydrogenase activity
JN280_RS07280	COG0469	pyruvate kinase activity
JN280_RS07285	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS07305	COG1309	transcriptional regulator
JN280_RS07310	COG2080	2 iron, 2 sulfur cluster binding
JN280_RS07330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JN280_RS07370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JN280_RS07380	COG2223	nitrite transmembrane transporter activity
JN280_RS07385	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JN280_RS07425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN280_RS07430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JN280_RS07475	COG0673	inositol 2-dehydrogenase activity
JN280_RS07490	COG1116	anion transmembrane transporter activity
JN280_RS07500	COG2072	flavoprotein involved in K transport
JN280_RS07505	COG3964	amidohydrolase
JN280_RS07510	COG0251	oxidation-reduction process
JN280_RS07520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN280_RS07525	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JN280_RS07530	COG0789	Transcriptional regulator
JN280_RS07560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JN280_RS07635	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
JN280_RS07645	COG2337	Toxic component of a toxin-antitoxin (TA) module
JN280_RS07655	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JN280_RS07655	COG3743	rRNA binding
JN280_RS07660	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JN280_RS07670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JN280_RS07680	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JN280_RS07685	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JN280_RS07690	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JN280_RS07695	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JN280_RS07705	COG0840	transmembrane signaling receptor activity
JN280_RS07715	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JN280_RS07725	COG2884	Cell division ATP-binding protein ftsE
JN280_RS07755	COG0287	Prephenate dehydrogenase
JN280_RS07760	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JN280_RS07775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JN280_RS07780	COG2264	protein methyltransferase activity
JN280_RS07795	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JN280_RS07800	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JN280_RS07835	COG4536	flavin adenine dinucleotide binding
JN280_RS07840	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JN280_RS07845	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JN280_RS07860	COG0825	malonyl-CoA metabolic process
JN280_RS07865	COG3034	peptidoglycan biosynthetic process
JN280_RS07870	COG0425	Belongs to the sulfur carrier protein TusA family
JN280_RS07875	COG2814	Major facilitator Superfamily
JN280_RS07885	COG0523	cobalamin synthesis protein
JN280_RS07890	COG1686	Belongs to the peptidase S11 family
JN280_RS07895	COG1473	amidohydrolase
JN280_RS07960	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS07965	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS07975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN280_RS07995	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
JN280_RS08005	COG0395	ABC-type sugar transport system, permease component
JN280_RS08020	COG4821	SIS domain
JN280_RS08025	COG2188	Transcriptional regulator
JN280_RS08030	COG1070	Carbohydrate kinase
JN280_RS08035	COG2188	Transcriptional regulator
JN280_RS08045	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
JN280_RS08050	COG3608	succinylglutamate desuccinylase aspartoacylase
JN280_RS08055	COG0251	oxidation-reduction process
JN280_RS08070	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS08075	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS08080	COG1129	ABC transporter
JN280_RS08085	COG1879	ABC-type sugar transport system periplasmic component
JN280_RS08130	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JN280_RS08150	COG0217	transcriptional regulatory protein
JN280_RS08175	COG0405	Gamma-glutamyltransferase
JN280_RS08190	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JN280_RS08195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JN280_RS08200	COG0142	geranyltranstransferase activity
JN280_RS08205	COG0784	Response regulator, receiver
JN280_RS08205	COG2205	protein histidine kinase activity
JN280_RS08205	COG5002	protein histidine kinase activity
JN280_RS08215	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JN280_RS08225	COG0159	tryptophan synthase activity
JN280_RS08230	COG0133	tryptophan synthase activity
JN280_RS08260	COG0457	Tetratricopeptide repeat
JN280_RS08265	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JN280_RS08270	COG3152	Membrane
JN280_RS08285	COG0473	3-isopropylmalate dehydrogenase activity
JN280_RS08295	COG0251	oxidation-reduction process
JN280_RS08305	COG0066	3-isopropylmalate dehydratase activity
JN280_RS08330	COG2205	protein histidine kinase activity
JN280_RS08335	COG0745	RESPONSE REGULATOR receiver
JN280_RS08370	COG4191	Histidine kinase
JN280_RS08395	COG0583	DNA-binding transcription factor activity
JN280_RS08415	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JN280_RS08420	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JN280_RS08440	COG2234	aminopeptidase activity
JN280_RS08455	COG4974	Belongs to the 'phage' integrase family
JN280_RS08460	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JN280_RS08465	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JN280_RS08475	COG0183	Belongs to the thiolase family
JN280_RS08480	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS08490	COG3226	Transcriptional regulator
JN280_RS08495	COG1960	acyl-CoA dehydrogenase activity
JN280_RS08530	COG2301	Belongs to the HpcH HpaI aldolase family
JN280_RS08540	COG1960	acyl-CoA dehydrogenase activity
JN280_RS08560	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS08570	COG0583	DNA-binding transcription factor activity
JN280_RS08580	COG0183	Belongs to the thiolase family
JN280_RS08585	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS08590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN280_RS08600	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JN280_RS08605	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JN280_RS08610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN280_RS08615	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
JN280_RS08625	COG1960	acyl-CoA dehydrogenase activity
JN280_RS08655	COG2948	multi-organism process
JN280_RS08685	COG3451	type IV secretory pathway VirB4
JN280_RS08695	COG3838	Conjugal transfer protein Trbc
JN280_RS08700	COG4962	Type ii secretion system protein e
JN280_RS08725	COG0741	lytic transglycosylase activity
JN280_RS08750	COG1192	Involved in chromosome partitioning
JN280_RS08775	COG1476	TRANSCRIPTIONal
JN280_RS08780	COG5489	Protein of unknown function (DUF736)
JN280_RS08825	COG4227	nucleotidyltransferase activity
JN280_RS08865	COG0459	protein refolding
JN280_RS08880	COG3239	Fatty acid desaturase
JN280_RS08905	COG1278	Cold shock
JN280_RS08975	COG4974	Belongs to the 'phage' integrase family
JN280_RS08985	COG3842	ATPase activity
JN280_RS08995	COG1177	transmembrane transport
JN280_RS09010	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS09020	COG0183	Belongs to the thiolase family
JN280_RS09025	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JN280_RS09025	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JN280_RS09030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JN280_RS09040	COG0154	amidase activity
JN280_RS09045	COG0154	amidase activity
JN280_RS09055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JN280_RS09065	COG2771	luxR family
JN280_RS09075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN280_RS09085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN280_RS09090	COG3842	ATPase activity
JN280_RS09115	COG2814	Major facilitator Superfamily
JN280_RS09120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN280_RS09125	COG1063	alcohol dehydrogenase
JN280_RS09135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN280_RS09185	COG3177	Filamentation induced by cAMP protein fic
JN280_RS09205	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JN280_RS09210	COG2835	tetraacyldisaccharide 4'-kinase activity
JN280_RS09215	COG0587	DNA-directed DNA polymerase activity
JN280_RS09310	COG1522	sequence-specific DNA binding
JN280_RS09345	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JN280_RS09365	COG1609	Transcriptional regulator
JN280_RS09375	COG1129	ABC transporter
JN280_RS09380	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS09395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JN280_RS09395	COG1116	anion transmembrane transporter activity
JN280_RS09400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN280_RS09405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JN280_RS09405	COG1116	anion transmembrane transporter activity
JN280_RS09415	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JN280_RS09440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JN280_RS09445	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
JN280_RS09455	COG0640	Transcriptional regulator
JN280_RS09470	COG3321	synthase
JN280_RS09470	COG0604	alcohol dehydrogenase
JN280_RS09485	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JN280_RS09485	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JN280_RS09490	COG0501	Belongs to the peptidase M48B family
JN280_RS09500	COG2270	Major facilitator Superfamily
JN280_RS09510	COG0670	Belongs to the BI1 family
JN280_RS09520	COG3246	L-lysine catabolic process to acetate
JN280_RS09525	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JN280_RS09540	COG0765	amino acid transport
JN280_RS09545	COG0765	amino acid transport
JN280_RS09565	COG4181	ATPase activity
JN280_RS09575	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JN280_RS09585	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JN280_RS09590	COG2154	pterin-4-alpha-carbinolamine dehydratase
JN280_RS09595	COG3339	Conserved Protein
JN280_RS09635	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JN280_RS09655	COG3609	addiction module antidote protein, CC2985 family
JN280_RS09660	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JN280_RS09670	COG0137	argininosuccinate synthase activity
JN280_RS09685	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JN280_RS09690	COG1217	gtp-binding protein TYPA
JN280_RS09735	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JN280_RS09740	COG4133	protoheme IX ABC transporter activity
JN280_RS09745	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JN280_RS09750	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JN280_RS09760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JN280_RS09765	COG0385	Bile acid
JN280_RS09780	COG2917	probably involved in intracellular septation
JN280_RS09785	COG0552	protein localization to endoplasmic reticulum
JN280_RS09790	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JN280_RS09795	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JN280_RS09810	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JN280_RS09815	COG0039	L-malate dehydrogenase activity
JN280_RS09820	COG0045	succinate-CoA ligase (ADP-forming) activity
JN280_RS09825	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JN280_RS09835	COG0508	dehydrogenase complex catalyzes the overall conversion of
JN280_RS09875	COG4974	Belongs to the 'phage' integrase family
JN280_RS09895	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JN280_RS09900	COG0336	Belongs to the RNA methyltransferase TrmD family
JN280_RS09910	COG0335	large ribosomal subunit rRNA binding
JN280_RS09920	COG1764	response to oxidative stress
JN280_RS09925	COG1846	Transcriptional regulator
JN280_RS09930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN280_RS09935	COG0765	amino acid transport
JN280_RS09955	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JN280_RS09960	COG3706	GGDEF domain
JN280_RS09990	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
JN280_RS10010	COG1764	response to oxidative stress
JN280_RS10020	COG1846	Transcriptional regulator
JN280_RS10025	COG0697	spore germination
JN280_RS10040	COG3795	YCII-related domain
JN280_RS10045	COG4941	Belongs to the sigma-70 factor family
JN280_RS10075	COG0583	DNA-binding transcription factor activity
JN280_RS10090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JN280_RS10090	COG1116	anion transmembrane transporter activity
JN280_RS10100	COG2188	Transcriptional regulator
JN280_RS10115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JN280_RS10120	COG0697	spore germination
JN280_RS10130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN280_RS10135	COG1946	Acyl-CoA thioesterase
JN280_RS10140	COG0347	Belongs to the P(II) protein family
JN280_RS10145	COG0004	ammonium transporteR
JN280_RS10160	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JN280_RS10165	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS10170	COG0436	Aminotransferase
JN280_RS10190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JN280_RS10220	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JN280_RS10225	COG1984	allophanate hydrolase subunit 2
JN280_RS10230	COG1802	Transcriptional regulator
JN280_RS10250	COG0006	proline dipeptidase activity
JN280_RS10255	COG1674	ftsk spoiiie
JN280_RS10255	COG2261	transglycosylase associated protein
JN280_RS10260	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JN280_RS10275	COG0745	RESPONSE REGULATOR receiver
JN280_RS10290	COG0583	DNA-binding transcription factor activity
JN280_RS10320	COG3391	amine dehydrogenase activity
JN280_RS10325	COG2264	protein methyltransferase activity
JN280_RS10340	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JN280_RS10345	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JN280_RS10350	COG0181	hydroxymethylbilane synthase activity
JN280_RS10375	COG3321	synthase
JN280_RS10375	COG0604	alcohol dehydrogenase
JN280_RS10375	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS10380	COG0583	DNA-binding transcription factor activity
JN280_RS10385	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JN280_RS10395	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JN280_RS10410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JN280_RS10425	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS10450	COG3132	Protein of unknown function, DUF480
JN280_RS10495	COG0823	Involved in the tonB-independent uptake of proteins
JN280_RS10495	COG1506	peptidase
JN280_RS10500	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS10505	COG3842	ATPase activity
JN280_RS10510	COG0395	ABC-type sugar transport system, permease component
JN280_RS10515	COG1175	transmembrane transport
JN280_RS10530	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
JN280_RS10540	COG1609	Transcriptional regulator
JN280_RS10545	COG2195	Cleaves the N-terminal amino acid of tripeptides
JN280_RS10550	COG0708	Exodeoxyribonuclease III
JN280_RS10575	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JN280_RS10605	COG0668	transmembrane transport
JN280_RS10615	COG0668	transmembrane transport
JN280_RS10620	COG0840	transmembrane signaling receptor activity
JN280_RS10640	COG1872	DUF167
JN280_RS10650	COG0702	epimerase
JN280_RS10660	COG0254	rRNA binding
JN280_RS10665	COG1132	(ABC) transporter
JN280_RS10700	COG1272	protein, Hemolysin III
JN280_RS10705	COG0483	inositol monophosphate 1-phosphatase activity
JN280_RS10725	COG0352	thiamine-phosphate diphosphorylase activity
JN280_RS10755	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JN280_RS10760	COG0632	four-way junction helicase activity
JN280_RS10775	COG2255	four-way junction helicase activity
JN280_RS10785	COG0824	Thioesterase
JN280_RS10795	COG0848	biopolymer transport protein
JN280_RS10810	COG2885	chlorophyll binding
JN280_RS10820	COG0037	tRNA processing
JN280_RS10825	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JN280_RS10850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JN280_RS10865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JN280_RS10915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JN280_RS11100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JN280_RS11105	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JN280_RS11110	COG0471	metal ion transport
JN280_RS11110	COG3273	potassium ion transport
JN280_RS11120	COG2719	SpoVR family
JN280_RS11125	COG2718	Belongs to the UPF0229 family
JN280_RS11130	COG2766	serine protein kinase
JN280_RS11150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JN280_RS11160	COG5642	Protein of unknown function (DUF2384)
JN280_RS11175	COG2176	DNA-directed DNA polymerase activity
JN280_RS11175	COG5002	protein histidine kinase activity
JN280_RS11185	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JN280_RS11195	COG1879	ABC-type sugar transport system periplasmic component
JN280_RS11200	COG1129	ABC transporter
JN280_RS11205	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS11210	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JN280_RS11215	COG0564	pseudouridine synthase activity
JN280_RS11225	COG0346	lactoylglutathione lyase activity
JN280_RS11235	COG2207	Transcriptional regulator
JN280_RS11265	COG1672	PFAM Archaeal ATPase
JN280_RS11265	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JN280_RS11300	COG0573	inorganic phosphate transmembrane transporter activity
JN280_RS11310	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JN280_RS11315	COG0704	Plays a role in the regulation of phosphate uptake
JN280_RS11320	COG0745	RESPONSE REGULATOR receiver
JN280_RS11340	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JN280_RS11360	COG4213	ABC transporter substrate-binding protein
JN280_RS11365	COG4214	carbohydrate transport
JN280_RS11370	COG1129	ABC transporter
JN280_RS11400	COG0784	Response regulator, receiver
JN280_RS11420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JN280_RS11440	COG0346	lactoylglutathione lyase activity
JN280_RS11445	COG0400	carboxylic ester hydrolase activity
JN280_RS11450	COG2388	GCN5-related N-acetyl-transferase
JN280_RS11470	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JN280_RS11485	COG2264	protein methyltransferase activity
JN280_RS11505	COG2814	Major facilitator Superfamily
JN280_RS11520	COG1176	ABC-type spermidine putrescine transport system, permease component I
JN280_RS11525	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JN280_RS11570	COG3842	ATPase activity
JN280_RS11580	COG1175	transmembrane transport
JN280_RS11600	COG0483	inositol monophosphate 1-phosphatase activity
JN280_RS11610	COG2203	Gaf domain
JN280_RS11610	COG2200	EAL domain
JN280_RS11610	COG2199	diguanylate cyclase activity
JN280_RS11620	COG0745	RESPONSE REGULATOR receiver
JN280_RS11635	COG4589	Belongs to the CDS family
JN280_RS11645	COG2267	carboxylic ester hydrolase activity
JN280_RS11650	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JN280_RS11665	COG0848	biopolymer transport protein
JN280_RS11705	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JN280_RS11710	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS11715	COG0028	Belongs to the TPP enzyme family
JN280_RS11740	COG1012	belongs to the aldehyde dehydrogenase family
JN280_RS11750	COG1253	flavin adenine dinucleotide binding
JN280_RS11755	COG1692	metallophosphoesterase
JN280_RS11760	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JN280_RS11785	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JN280_RS11805	COG3468	outer membrane autotransporter barrel domain protein
JN280_RS11810	COG3750	Belongs to the UPF0335 family
JN280_RS11820	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
JN280_RS11830	COG4143	(ABC) transporter
JN280_RS11840	COG0488	(ABC) transporter
JN280_RS11855	COG1132	(ABC) transporter
JN280_RS11860	COG1215	transferase activity, transferring glycosyl groups
JN280_RS11865	COG1216	Glycosyl transferase, family 2
JN280_RS11870	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JN280_RS11870	COG2755	lipolytic protein G-D-S-L family
JN280_RS11930	COG0165	Argininosuccinate lyase
JN280_RS11935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JN280_RS11940	COG1250	3-hydroxyacyl-CoA dehydrogenase
JN280_RS11945	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JN280_RS11950	COG2086	electron transfer activity
JN280_RS11955	COG1280	lysine exporter protein (LysE YggA)
JN280_RS11975	COG0300	oxidoreductase activity
JN280_RS11990	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JN280_RS12020	COG2814	Major facilitator Superfamily
JN280_RS12025	COG2272	Belongs to the type-B carboxylesterase lipase family
JN280_RS12030	COG0583	DNA-binding transcription factor activity
JN280_RS12050	COG3685	Protein conserved in bacteria
JN280_RS12105	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
JN280_RS12125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JN280_RS12150	COG3284	Transcriptional regulator
JN280_RS12155	COG1063	alcohol dehydrogenase
JN280_RS12190	COG3350	monooxygenase activity
JN280_RS12200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JN280_RS12225	COG0459	protein refolding
JN280_RS12230	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JN280_RS12255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JN280_RS12265	COG1473	amidohydrolase
JN280_RS12280	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
JN280_RS12310	COG0653	protein targeting
JN280_RS12315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JN280_RS12325	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JN280_RS12335	COG0494	nUDIX hydrolase
JN280_RS12350	COG2226	methyltransferase
JN280_RS12355	COG1040	competence protein
JN280_RS12365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JN280_RS12385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JN280_RS12400	COG0527	aspartate kinase activity
JN280_RS12405	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
JN280_RS12410	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JN280_RS12415	COG2890	protein-(glutamine-N5) methyltransferase activity
JN280_RS12425	COG0542	response to heat
JN280_RS12435	COG1376	ErfK ybiS ycfS ynhG family protein
JN280_RS12440	COG0477	Major facilitator Superfamily
JN280_RS12445	COG0739	heme binding
JN280_RS12490	COG0559	Belongs to the binding-protein-dependent transport system permease family
JN280_RS12550	COG0459	protein refolding
JN280_RS12570	COG3278	Belongs to the heme-copper respiratory oxidase family
JN280_RS12595	COG0446	pyridine nucleotide-disulphide oxidoreductase
JN280_RS12620	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JN280_RS12625	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JN280_RS12630	COG2080	2 iron, 2 sulfur cluster binding
JN280_RS12645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN280_RS12665	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JN280_RS12670	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS12680	COG0367	asparagine synthase
JN280_RS12690	COG3119	arylsulfatase activity
JN280_RS12705	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS12740	COG1079	Belongs to the binding-protein-dependent transport system permease family
JN280_RS12745	COG4603	Belongs to the binding-protein-dependent transport system permease family
JN280_RS12750	COG3845	ABC transporter
JN280_RS12780	COG0625	glutathione transferase activity
JN280_RS12785	COG0402	S-adenosylhomocysteine deaminase activity
JN280_RS12800	COG4948	Mandelate Racemase Muconate Lactonizing
JN280_RS12805	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JN280_RS12810	COG0205	6-phosphofructokinase activity
JN280_RS12815	COG1388	LysM domain
JN280_RS12815	COG1376	ErfK ybiS ycfS ynhG family protein
JN280_RS12820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JN280_RS12825	COG1280	lysine exporter protein (LysE YggA)
JN280_RS12835	COG1070	Carbohydrate kinase
JN280_RS12840	COG2115	Belongs to the xylose isomerase family
JN280_RS12850	COG4335	DNA alkylation repair
JN280_RS12855	COG1312	Catalyzes the dehydration of D-mannonate
JN280_RS12860	COG0246	Mannitol dehydrogenase
JN280_RS12865	COG1414	Transcriptional regulator
JN280_RS12870	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JN280_RS12875	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JN280_RS12880	COG0183	Belongs to the thiolase family
JN280_RS12890	COG4456	Virulence-associated protein
JN280_RS12900	COG3246	L-lysine catabolic process to acetate
JN280_RS12905	COG1250	3-hydroxyacyl-CoA dehydrogenase
JN280_RS12910	COG1960	acyl-CoA dehydrogenase activity
JN280_RS12925	COG0657	acetylesterase activity
JN280_RS12930	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
JN280_RS12930	COG2273	Hydrolase Family 16
JN280_RS12945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN280_RS12950	COG0601	transmembrane transport
JN280_RS12975	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
JN280_RS12980	COG3257	ureidoglycine aminohydrolase activity
JN280_RS12990	COG2351	hydroxyisourate hydrolase activity
JN280_RS13000	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JN280_RS13010	COG0683	leucine binding
JN280_RS13025	COG1129	ABC transporter
JN280_RS13035	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JN280_RS13045	COG2267	carboxylic ester hydrolase activity
JN280_RS13080	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JN280_RS13085	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JN280_RS13095	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JN280_RS13100	COG0583	DNA-binding transcription factor activity
JN280_RS13110	COG0402	S-adenosylhomocysteine deaminase activity
JN280_RS13115	COG4702	Belongs to the UPF0303 family
JN280_RS13125	COG0174	glutamine synthetase
JN280_RS13130	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JN280_RS13135	COG3177	Filamentation induced by cAMP protein fic
JN280_RS13140	COG0583	DNA-binding transcription factor activity
JN280_RS13150	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN280_RS13165	COG4175	Glycine betaine
JN280_RS13165	COG3448	diguanylate cyclase activity
JN280_RS13170	COG0604	alcohol dehydrogenase
JN280_RS13220	COG1902	pentaerythritol trinitrate reductase activity
JN280_RS13220	COG0446	pyridine nucleotide-disulphide oxidoreductase
JN280_RS13225	COG0583	DNA-binding transcription factor activity
JN280_RS13230	COG5598	trimethylamine methyltransferase
JN280_RS13235	COG1902	pentaerythritol trinitrate reductase activity
JN280_RS13235	COG0446	pyridine nucleotide-disulphide oxidoreductase
JN280_RS13240	COG0747	negative chemotaxis
JN280_RS13245	COG5012	cobalamin binding
JN280_RS13255	COG0523	cobalamin synthesis protein
JN280_RS13265	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JN280_RS13270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JN280_RS13275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JN280_RS13280	COG1120	ATPase activity
JN280_RS13305	COG1609	Transcriptional regulator
JN280_RS13310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JN280_RS13315	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JN280_RS13320	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
JN280_RS13325	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
JN280_RS13335	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JN280_RS13365	COG5001	Diguanylate cyclase
JN280_RS13380	COG1022	Amp-dependent synthetase and ligase
JN280_RS13445	COG4948	Mandelate Racemase Muconate Lactonizing
JN280_RS13455	COG0402	S-adenosylhomocysteine deaminase activity
JN280_RS13465	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JN280_RS13480	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JN280_RS13495	COG1942	4-Oxalocrotonate Tautomerase
JN280_RS13500	COG1335	isochorismatase
JN280_RS13515	COG0523	cobalamin synthesis protein
JN280_RS13530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN280_RS13535	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
JN280_RS13555	COG2814	Major facilitator Superfamily
JN280_RS13575	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JN280_RS13595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN280_RS13610	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JN280_RS13610	COG0446	pyridine nucleotide-disulphide oxidoreductase
JN280_RS13625	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JN280_RS13630	COG1522	sequence-specific DNA binding
JN280_RS13640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JN280_RS13645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JN280_RS13650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JN280_RS13655	COG2197	response regulator
JN280_RS13680	COG1309	transcriptional regulator
JN280_RS13685	COG1960	acyl-CoA dehydrogenase activity
JN280_RS13690	COG3321	synthase
JN280_RS13690	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS13690	COG0604	alcohol dehydrogenase
JN280_RS13720	COG1022	Amp-dependent synthetase and ligase
JN280_RS13740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JN280_RS13770	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
JN280_RS13805	COG3842	ATPase activity
JN280_RS13845	COG1069	ribulokinase activity
JN280_RS13855	COG4214	carbohydrate transport
JN280_RS13900	COG0071	Belongs to the small heat shock protein (HSP20) family
JN280_RS13915	COG2161	toxin-antitoxin pair type II binding
JN280_RS13920	COG0067	glutamate synthase
JN280_RS13920	COG0069	glutamate synthase activity
JN280_RS13920	COG0070	glutamate synthase
JN280_RS13930	COG2161	toxin-antitoxin pair type II binding
JN280_RS13935	COG4115	mRNA cleavage
JN280_RS13945	COG2951	lytic endotransglycosylase activity
JN280_RS13950	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JN280_RS14000	COG2313	pseudouridylate synthase activity
JN280_RS14005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JN280_RS14015	COG0330	HflC and HflK could
JN280_RS14020	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JN280_RS14025	COG0737	Belongs to the 5'-nucleotidase family
JN280_RS14030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JN280_RS14040	COG5310	Homospermidine synthase
JN280_RS14050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JN280_RS14055	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JN280_RS14055	COG0512	Glutamine amidotransferase of anthranilate synthase
JN280_RS14065	COG2204	response regulator
JN280_RS14070	COG3108	Peptidase M15
JN280_RS14075	COG0800	Aldolase
JN280_RS14080	COG1054	Belongs to the UPF0176 family
JN280_RS14100	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS14120	COG1230	cation diffusion facilitator family transporter
JN280_RS14130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JN280_RS14160	COG1335	isochorismatase
JN280_RS14165	COG1733	regulation of RNA biosynthetic process
JN280_RS14170	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
JN280_RS14180	COG0583	DNA-binding transcription factor activity
JN280_RS14210	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS14215	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JN280_RS14220	COG1960	acyl-CoA dehydrogenase activity
JN280_RS14260	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JN280_RS14275	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
JN280_RS14280	COG4423	Transcription factor
JN280_RS14285	COG3119	arylsulfatase activity
JN280_RS14305	COG1940	carbohydrate kinase activity
JN280_RS14315	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JN280_RS14320	COG5443	negative regulation of bacterial-type flagellum assembly
JN280_RS14325	COG5442	Flagellar protein FlaF
JN280_RS14380	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JN280_RS14385	COG1338	Plays a role in the flagellum-specific transport system
JN280_RS14395	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
JN280_RS14405	COG1706	bacterial-type flagellum-dependent cell motility
JN280_RS14410	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
JN280_RS14415	COG4786	Flagellar basal body rod
JN280_RS14420	COG1677	Flagellar hook-basal body complex protein FliE
JN280_RS14425	COG1558	bacterial-type flagellum-dependent cell motility
JN280_RS14430	COG1815	bacterial-type flagellum-dependent cell motility
JN280_RS14440	COG1157	protein secretion by the type III secretion system
JN280_RS14445	COG4786	Flagellar basal body rod
JN280_RS14455	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JN280_RS14460	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JN280_RS14465	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JN280_RS14470	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JN280_RS14475	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JN280_RS14495	COG0840	transmembrane signaling receptor activity
JN280_RS14510	COG1674	ftsk spoiiie
JN280_RS14515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JN280_RS14520	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
JN280_RS14555	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
JN280_RS14560	COG0745	RESPONSE REGULATOR receiver
JN280_RS14565	COG2201	protein-glutamate methylesterase activity
JN280_RS14570	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JN280_RS14575	COG0835	chemotaxis
JN280_RS14580	COG2198	Histidine kinase
JN280_RS14580	COG0643	Histidine kinase
JN280_RS14595	COG0840	transmembrane signaling receptor activity
JN280_RS14600	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JN280_RS14610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JN280_RS14615	COG0626	cystathionine gamma-synthase activity
JN280_RS14630	COG0673	inositol 2-dehydrogenase activity
JN280_RS14640	COG3718	enzyme involved in inositol metabolism
JN280_RS14655	COG3962	Belongs to the TPP enzyme family
JN280_RS14660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JN280_RS14675	COG1012	belongs to the aldehyde dehydrogenase family
JN280_RS14700	COG2094	Belongs to the DNA glycosylase MPG family
JN280_RS14725	COG1418	mRNA catabolic process
JN280_RS14765	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS14790	COG1175	transmembrane transport
JN280_RS14800	COG3842	ATPase activity
JN280_RS14810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JN280_RS14855	COG2326	polyphosphate kinase activity
JN280_RS14905	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
JN280_RS14930	COG5383	Protein conserved in bacteria
JN280_RS14935	COG1012	belongs to the aldehyde dehydrogenase family
JN280_RS14960	COG1126	abc transporter atp-binding protein
JN280_RS14965	COG0765	amino acid transport
JN280_RS14970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN280_RS14975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JN280_RS14985	COG3246	L-lysine catabolic process to acetate
JN280_RS14995	COG0024	Methionine aminopeptidase
JN280_RS15005	COG0601	transmembrane transport
JN280_RS15010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN280_RS15025	COG0444	Belongs to the ABC transporter superfamily
JN280_RS15030	COG4608	Belongs to the ABC transporter superfamily
JN280_RS15040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JN280_RS15055	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JN280_RS15060	COG1595	DNA-templated transcription, initiation
JN280_RS15100	COG2070	2-Nitropropane dioxygenase
JN280_RS15150	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
JN280_RS15155	COG0786	glutamate:sodium symporter activity
JN280_RS15200	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS15210	COG1137	ATPase activity
JN280_RS15230	COG1063	alcohol dehydrogenase
JN280_RS15255	COG1733	regulation of RNA biosynthetic process
JN280_RS15305	COG1914	H( )-stimulated, divalent metal cation uptake system
JN280_RS15310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JN280_RS15320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JN280_RS15340	COG0028	Belongs to the TPP enzyme family
JN280_RS15345	COG0277	FAD linked oxidase domain protein
JN280_RS15350	COG1126	abc transporter atp-binding protein
JN280_RS15355	COG0765	amino acid transport
JN280_RS15360	COG0765	amino acid transport
JN280_RS15360	COG0765	amino acid transport
JN280_RS15365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN280_RS15370	COG0583	DNA-binding transcription factor activity
JN280_RS15375	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS15380	COG4221	oxidoreductase activity
JN280_RS15385	COG2186	Transcriptional regulator
JN280_RS15405	COG2084	Dehydrogenase
JN280_RS15440	COG1802	Transcriptional regulator
JN280_RS15445	COG3119	arylsulfatase activity
JN280_RS15465	COG0473	3-isopropylmalate dehydrogenase activity
JN280_RS15470	COG1012	belongs to the aldehyde dehydrogenase family
JN280_RS15480	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS15485	COG0583	DNA-binding transcription factor activity
JN280_RS15490	COG0747	negative chemotaxis
JN280_RS15495	COG0601	transmembrane transport
JN280_RS15500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN280_RS15505	COG0154	amidase activity
JN280_RS15510	COG0444	Belongs to the ABC transporter superfamily
JN280_RS15520	COG0154	amidase activity
JN280_RS15530	COG0281	malic enzyme
JN280_RS15535	COG0114	fumarate hydratase activity
JN280_RS15545	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JN280_RS15545	COG2124	cytochrome p450
JN280_RS15550	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS15595	COG5342	invasion associated locus B
JN280_RS15610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JN280_RS15630	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JN280_RS15650	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS15655	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS15660	COG0778	Nitroreductase
JN280_RS15670	COG1960	acyl-CoA dehydrogenase activity
JN280_RS15675	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS15680	COG2130	NADP-dependent
JN280_RS15700	COG1301	dicarboxylic acid transport
JN280_RS15705	COG4191	Histidine kinase
JN280_RS15710	COG2204	response regulator
JN280_RS15715	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS15720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN280_RS15745	COG0559	Belongs to the binding-protein-dependent transport system permease family
JN280_RS15750	COG4214	carbohydrate transport
JN280_RS15755	COG1024	Enoyl-CoA hydratase
JN280_RS15775	COG1024	Enoyl-CoA hydratase
JN280_RS15775	COG1250	3-hydroxyacyl-CoA dehydrogenase
JN280_RS15780	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS15790	COG1960	acyl-CoA dehydrogenase activity
JN280_RS15800	COG3246	L-lysine catabolic process to acetate
JN280_RS15810	COG1960	acyl-CoA dehydrogenase activity
JN280_RS15815	COG0427	acetyl-CoA hydrolase
JN280_RS15820	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JN280_RS15840	COG2030	dehydratase
JN280_RS15850	COG1960	acyl-CoA dehydrogenase activity
JN280_RS15855	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS15860	COG2030	dehydratase
JN280_RS15865	COG4221	oxidoreductase activity
JN280_RS15875	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS15880	COG1960	acyl-CoA dehydrogenase activity
JN280_RS15885	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS15910	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS15915	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS15940	COG1079	Belongs to the binding-protein-dependent transport system permease family
JN280_RS15965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN280_RS15995	COG2086	electron transfer activity
JN280_RS16000	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JN280_RS16035	COG0596	Alpha beta hydrolase
JN280_RS16040	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS16045	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JN280_RS16050	COG3181	Tripartite tricarboxylate transporter family receptor
JN280_RS16065	COG1802	Transcriptional regulator
JN280_RS16080	COG3706	GGDEF domain
JN280_RS16095	COG0482	sulfurtransferase activity
JN280_RS16120	COG2204	response regulator
JN280_RS16155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN280_RS16165	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JN280_RS16175	COG4176	ABC-type proline glycine betaine transport system permease component
JN280_RS16185	COG1435	thymidine kinase activity
JN280_RS16220	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JN280_RS16235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JN280_RS16240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JN280_RS16245	COG1126	abc transporter atp-binding protein
JN280_RS16250	COG0765	amino acid transport
JN280_RS16255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN280_RS16270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JN280_RS16275	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JN280_RS16275	COG0512	Glutamine amidotransferase of anthranilate synthase
JN280_RS16295	COG3180	Ammonia monooxygenase
JN280_RS16300	COG2207	Transcriptional regulator
JN280_RS16305	COG2223	nitrite transmembrane transporter activity
JN280_RS16320	COG2321	neutral zinc metallopeptidase
JN280_RS16325	COG0505	Belongs to the CarA family
JN280_RS16365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN280_RS16370	COG1024	Enoyl-CoA hydratase
JN280_RS16375	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS16385	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS16395	COG1129	ABC transporter
JN280_RS16410	COG0747	negative chemotaxis
JN280_RS16435	COG1017	nitric oxide dioxygenase activity
JN280_RS16435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JN280_RS16455	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS16465	COG0456	acetyltransferase
JN280_RS16500	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JN280_RS16510	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS16515	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS16520	COG1129	ABC transporter
JN280_RS16525	COG1879	ABC-type sugar transport system periplasmic component
JN280_RS16535	COG1940	carbohydrate kinase activity
JN280_RS16540	COG0583	DNA-binding transcription factor activity
JN280_RS16545	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JN280_RS16550	COG1233	COG1233 Phytoene dehydrogenase and related
JN280_RS16555	COG1053	succinate dehydrogenase
JN280_RS16565	COG0596	Alpha beta hydrolase
JN280_RS16585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN280_RS16595	COG0432	Pfam Uncharacterised protein family UPF0047
JN280_RS16605	COG1695	Transcriptional regulator
JN280_RS16640	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JN280_RS16665	COG0494	nUDIX hydrolase
JN280_RS16670	COG0435	Glutathione S-transferase
JN280_RS16695	COG0714	Associated with various cellular activities
JN280_RS16705	COG0494	nUDIX hydrolase
JN280_RS16710	COG0617	tRNA 3'-terminal CCA addition
JN280_RS16725	COG0408	coproporphyrinogen oxidase activity
JN280_RS16740	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JN280_RS16745	COG1132	(ABC) transporter
JN280_RS16750	COG1132	(ABC) transporter
JN280_RS16770	COG2857	Cytochrome c1
JN280_RS16770	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JN280_RS16775	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JN280_RS16785	COG3795	YCII-related domain
JN280_RS16815	COG4175	Glycine betaine
JN280_RS16820	COG4176	ABC-type proline glycine betaine transport system permease component
JN280_RS16830	COG0012	GTP binding
JN280_RS16835	COG0193	aminoacyl-tRNA hydrolase activity
JN280_RS16840	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JN280_RS16850	COG0583	DNA-binding transcription factor activity
JN280_RS16865	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JN280_RS16875	COG0006	proline dipeptidase activity
JN280_RS16880	COG1496	oxidoreductase activity
JN280_RS16890	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JN280_RS16905	COG3609	addiction module antidote protein, CC2985 family
JN280_RS16920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JN280_RS16940	COG2205	protein histidine kinase activity
JN280_RS16945	COG0745	RESPONSE REGULATOR receiver
JN280_RS16950	COG1846	Transcriptional regulator
JN280_RS16955	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JN280_RS16970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JN280_RS16980	COG1278	Cold shock
JN280_RS16985	COG1278	Cold shock
JN280_RS16995	COG0556	nucleotide-excision repair
JN280_RS17025	COG4948	Mandelate Racemase Muconate Lactonizing
JN280_RS17030	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
JN280_RS17045	COG0431	NADPH-dependent FMN reductase
JN280_RS17050	COG1253	flavin adenine dinucleotide binding
JN280_RS17085	COG2133	pyrroloquinoline quinone binding
JN280_RS17095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JN280_RS17100	COG1960	acyl-CoA dehydrogenase activity
JN280_RS17105	COG0859	PFAM glycosyl transferase family 9
JN280_RS17110	COG0859	PFAM glycosyl transferase family 9
JN280_RS17115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JN280_RS17120	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JN280_RS17120	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JN280_RS17125	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JN280_RS17130	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JN280_RS17135	COG1522	sequence-specific DNA binding
JN280_RS17140	COG0492	ferredoxin-NADP+ reductase activity
JN280_RS17145	COG0583	DNA-binding transcription factor activity
JN280_RS17150	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JN280_RS17155	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JN280_RS17165	COG0436	Aminotransferase
JN280_RS17200	COG0625	glutathione transferase activity
JN280_RS17205	COG1278	Cold shock
JN280_RS17240	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JN280_RS17260	COG2814	Major facilitator Superfamily
JN280_RS17280	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS17285	COG2862	Uncharacterized protein family, UPF0114
JN280_RS17295	COG2983	Belongs to the UPF0260 family
JN280_RS17330	COG1012	belongs to the aldehyde dehydrogenase family
JN280_RS17335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JN280_RS17350	COG3448	diguanylate cyclase activity
JN280_RS17350	COG4175	Glycine betaine
JN280_RS17355	COG4176	ABC-type proline glycine betaine transport system permease component
JN280_RS17360	COG4176	ABC-type proline glycine betaine transport system permease component
JN280_RS17375	COG2968	Membrane
JN280_RS17380	COG1396	sequence-specific DNA binding
JN280_RS17380	COG3800	Transcriptional regulator
JN280_RS17385	COG1268	BioY protein
JN280_RS17390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JN280_RS17395	COG4770	biotin carboxylase activity
JN280_RS17400	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JN280_RS17400	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JN280_RS17415	COG1086	Polysaccharide biosynthesis protein
JN280_RS17430	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JN280_RS17435	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS17450	COG1024	Enoyl-CoA hydratase
JN280_RS17460	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS17470	COG1024	Enoyl-CoA hydratase
JN280_RS17480	COG1960	acyl-CoA dehydrogenase activity
JN280_RS17485	COG0251	oxidation-reduction process
JN280_RS17495	COG0444	Belongs to the ABC transporter superfamily
JN280_RS17500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN280_RS17505	COG0601	transmembrane transport
JN280_RS17520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN280_RS17525	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JN280_RS17530	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
JN280_RS17550	COG3547	Transposase (IS116 IS110 IS902 family)
JN280_RS17575	COG3608	succinylglutamate desuccinylase aspartoacylase
JN280_RS17580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JN280_RS17595	COG3483	tryptophan 2,3-dioxygenase activity
JN280_RS17615	COG1129	ABC transporter
JN280_RS17630	COG2130	NADP-dependent
JN280_RS17635	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JN280_RS17635	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JN280_RS17645	COG1902	pentaerythritol trinitrate reductase activity
JN280_RS17650	COG2072	flavoprotein involved in K transport
JN280_RS17655	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS17660	COG1960	acyl-CoA dehydrogenase activity
JN280_RS17665	COG1024	Enoyl-CoA hydratase
JN280_RS17670	COG1960	acyl-CoA dehydrogenase activity
JN280_RS17705	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS17725	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
JN280_RS17730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JN280_RS17735	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS17745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN280_RS17765	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JN280_RS17770	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JN280_RS17775	COG3307	-O-antigen
JN280_RS17780	COG1596	polysaccharide export
JN280_RS17785	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JN280_RS17815	COG1215	transferase activity, transferring glycosyl groups
JN280_RS17825	COG2273	Hydrolase Family 16
JN280_RS17830	COG0438	transferase activity, transferring glycosyl groups
JN280_RS17835	COG1215	transferase activity, transferring glycosyl groups
JN280_RS17840	COG1215	transferase activity, transferring glycosyl groups
JN280_RS17845	COG1215	transferase activity, transferring glycosyl groups
JN280_RS17850	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JN280_RS17855	COG0489	protein tyrosine kinase activity
JN280_RS17855	COG3206	protein involved in exopolysaccharide biosynthesis
JN280_RS17860	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
JN280_RS17865	COG1091	dTDP-4-dehydrorhamnose reductase activity
JN280_RS17870	COG1309	transcriptional regulator
JN280_RS17875	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JN280_RS17880	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
JN280_RS17890	COG1744	ABC transporter substrate-binding protein PnrA-like
JN280_RS17895	COG1129	ABC transporter
JN280_RS17900	COG4603	Belongs to the binding-protein-dependent transport system permease family
JN280_RS17915	COG0402	S-adenosylhomocysteine deaminase activity
JN280_RS17940	COG1733	regulation of RNA biosynthetic process
JN280_RS17945	COG2186	Transcriptional regulator
JN280_RS17950	COG0179	Fumarylacetoacetate (FAA) hydrolase
JN280_RS17960	COG0402	S-adenosylhomocysteine deaminase activity
JN280_RS17965	COG0559	Belongs to the binding-protein-dependent transport system permease family
JN280_RS17985	COG5441	Belongs to the UPF0261 family
JN280_RS17990	COG2268	Band 7 protein
JN280_RS17990	COG2268	Band 7 protein
JN280_RS18010	COG3119	arylsulfatase activity
JN280_RS18025	COG5002	protein histidine kinase activity
JN280_RS18030	COG0745	RESPONSE REGULATOR receiver
JN280_RS18035	COG1012	belongs to the aldehyde dehydrogenase family
JN280_RS18045	COG4177	L-phenylalanine transmembrane transporter activity
JN280_RS18060	COG1137	ATPase activity
JN280_RS18075	COG2207	Transcriptional regulator
JN280_RS18085	COG3842	ATPase activity
JN280_RS18120	COG1228	amidohydrolase
JN280_RS18125	COG2986	histidine ammonia-lyase
JN280_RS18135	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JN280_RS18150	COG1368	sulfuric ester hydrolase activity
JN280_RS18155	COG1132	(ABC) transporter
JN280_RS18160	COG3459	Glycosyltransferase 36 associated
JN280_RS18175	COG4608	Belongs to the ABC transporter superfamily
JN280_RS18180	COG0444	Belongs to the ABC transporter superfamily
JN280_RS18185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN280_RS18190	COG0601	transmembrane transport
JN280_RS18195	COG0747	negative chemotaxis
JN280_RS18200	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JN280_RS18210	COG4208	sulfate ABC transporter
JN280_RS18215	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JN280_RS18225	COG3034	peptidoglycan biosynthetic process
JN280_RS18235	COG0789	Transcriptional regulator
JN280_RS18240	COG1238	metal cluster binding
JN280_RS18250	COG2002	toxin-antitoxin pair type II binding
JN280_RS18260	COG0492	ferredoxin-NADP+ reductase activity
JN280_RS18260	COG3118	belongs to the thioredoxin family
JN280_RS18270	COG4953	penicillin-binding protein 1C
JN280_RS18280	COG2373	Large extracellular alpha-helical protein
JN280_RS18285	COG0729	surface antigen
JN280_RS18295	COG0747	negative chemotaxis
JN280_RS18300	COG0601	transmembrane transport
JN280_RS18305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN280_RS18315	COG1132	(ABC) transporter
JN280_RS18320	COG2072	flavoprotein involved in K transport
JN280_RS18420	COG3119	arylsulfatase activity
JN280_RS18435	COG0590	tRNA wobble adenosine to inosine editing
JN280_RS18450	COG1309	transcriptional regulator
JN280_RS18455	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JN280_RS18490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN280_RS18495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN280_RS18500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JN280_RS18520	COG0583	DNA-binding transcription factor activity
JN280_RS18525	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JN280_RS18530	COG3485	protocatechuate 3,4-dioxygenase
JN280_RS18535	COG3485	protocatechuate 3,4-dioxygenase
JN280_RS18565	COG0463	Glycosyl transferase, family 2
JN280_RS18570	COG0028	Belongs to the TPP enzyme family
JN280_RS18575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN280_RS18580	COG2267	carboxylic ester hydrolase activity
JN280_RS18585	COG3706	GGDEF domain
JN280_RS18600	COG4106	trans-aconitate 2-methyltransferase activity
JN280_RS18625	COG1720	tRNA m6t6A37 methyltransferase activity
JN280_RS18630	COG2226	methyltransferase
JN280_RS18715	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JN280_RS18720	COG3023	N-Acetylmuramoyl-L-alanine amidase
JN280_RS18745	COG3668	Plasmid stabilization system
JN280_RS18750	COG0626	cystathionine gamma-synthase activity
JN280_RS18755	COG2001	Belongs to the MraZ family
JN280_RS18760	COG0275	rRNA processing
JN280_RS18775	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JN280_RS18785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JN280_RS18790	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JN280_RS18800	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JN280_RS18805	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JN280_RS18810	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JN280_RS18845	COG0326	Molecular chaperone. Has ATPase activity
JN280_RS18860	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JN280_RS18865	COG0628	permease
JN280_RS18870	COG4214	carbohydrate transport
JN280_RS18880	COG1879	ABC-type sugar transport system periplasmic component
JN280_RS18885	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JN280_RS18890	COG2852	Protein conserved in bacteria
JN280_RS18895	COG1181	Belongs to the D-alanine--D-alanine ligase family
JN280_RS18900	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JN280_RS18905	COG0849	cell division
JN280_RS18910	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JN280_RS18920	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JN280_RS18960	COG0006	proline dipeptidase activity
JN280_RS18970	COG2264	protein methyltransferase activity
JN280_RS18980	COG1999	signal sequence binding
JN280_RS19020	COG1388	LysM domain
JN280_RS19020	COG1376	ErfK ybiS ycfS ynhG family protein
JN280_RS19025	COG0210	DNA helicase
JN280_RS19035	COG1846	Transcriptional regulator
JN280_RS19085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN280_RS19110	COG4941	Belongs to the sigma-70 factor family
JN280_RS19115	COG3795	YCII-related domain
JN280_RS19155	COG0277	FAD linked oxidase domain protein
JN280_RS19245	COG2814	Major facilitator Superfamily
JN280_RS19260	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JN280_RS19300	COG0446	pyridine nucleotide-disulphide oxidoreductase
JN280_RS19320	COG0530	calcium, potassium:sodium antiporter activity
JN280_RS19355	COG0459	protein refolding
JN280_RS19360	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JN280_RS19375	COG0071	Belongs to the small heat shock protein (HSP20) family
JN280_RS19420	COG2239	Acts as a magnesium transporter
JN280_RS19425	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JN280_RS19450	COG0330	HflC and HflK could
JN280_RS19460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JN280_RS19485	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JN280_RS19530	COG0028	Belongs to the TPP enzyme family
JN280_RS19545	COG0440	acetolactate synthase activity
JN280_RS19580	COG1595	DNA-templated transcription, initiation
JN280_RS19585	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JN280_RS19595	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JN280_RS19605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JN280_RS19615	COG3158	transport of potassium into the cell
JN280_RS19630	COG1309	transcriptional regulator
JN280_RS19635	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JN280_RS19665	COG1136	(ABC) transporter
JN280_RS19665	COG0577	efflux transmembrane transporter activity
JN280_RS19670	COG1136	(ABC) transporter
JN280_RS19670	COG0577	efflux transmembrane transporter activity
JN280_RS19680	COG0384	phenazine biosynthesis protein PhzF
JN280_RS19720	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JN280_RS19725	COG3214	Protein conserved in bacteria
JN280_RS19730	COG2249	NAD(P)H dehydrogenase (quinone) activity
JN280_RS19735	COG2249	NAD(P)H dehydrogenase (quinone) activity
JN280_RS19745	COG0402	S-adenosylhomocysteine deaminase activity
JN280_RS19750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN280_RS19780	COG0436	Aminotransferase
JN280_RS19805	COG1309	transcriptional regulator
JN280_RS19810	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS19815	COG2207	Transcriptional regulator
JN280_RS19830	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS19835	COG3842	ATPase activity
JN280_RS19850	COG1177	transmembrane transport
JN280_RS19860	COG1063	alcohol dehydrogenase
JN280_RS19875	COG4459	periplasmic nitrate reductase
JN280_RS19900	COG3005	denitrification pathway
JN280_RS19930	COG0385	Bile acid
JN280_RS19935	COG2072	flavoprotein involved in K transport
JN280_RS19950	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JN280_RS19980	COG0446	pyridine nucleotide-disulphide oxidoreductase
JN280_RS19980	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JN280_RS19990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN280_RS19995	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
JN280_RS19995	COG3264	Mechanosensitive ion channel
JN280_RS20005	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JN280_RS20020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JN280_RS20060	COG0583	DNA-binding transcription factor activity
JN280_RS20075	COG2827	Endonuclease containing a URI domain
JN280_RS20080	COG1410	methionine synthase
JN280_RS20080	COG0646	methionine synthase
JN280_RS20120	COG5012	cobalamin binding
JN280_RS20125	COG5598	trimethylamine methyltransferase
JN280_RS20150	COG2304	oxidoreductase activity
JN280_RS20155	COG0646	methionine synthase
JN280_RS20155	COG1410	methionine synthase
JN280_RS20175	COG0006	proline dipeptidase activity
JN280_RS20240	COG1917	Cupin 2, conserved barrel domain protein
JN280_RS20245	COG1492	cobalamin metabolic process
JN280_RS20280	COG4172	Belongs to the ABC transporter superfamily
JN280_RS20285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN280_RS20295	COG0747	negative chemotaxis
JN280_RS20300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JN280_RS20325	COG0243	molybdopterin cofactor binding
JN280_RS20330	COG0437	4 iron, 4 sulfur cluster binding
JN280_RS20335	COG3302	dmso reductase anchor subunit
JN280_RS20345	COG3321	synthase
JN280_RS20345	COG0604	alcohol dehydrogenase
JN280_RS20350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JN280_RS20360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JN280_RS20370	COG5001	Diguanylate cyclase
JN280_RS20375	COG3447	MASE1 domain protein
JN280_RS20375	COG5001	Diguanylate cyclase
JN280_RS20375	COG5002	protein histidine kinase activity
JN280_RS20400	COG2017	converts alpha-aldose to the beta-anomer
JN280_RS20405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JN280_RS20415	COG1858	cytochrome C peroxidase
JN280_RS20420	COG1522	sequence-specific DNA binding
JN280_RS20425	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JN280_RS20425	COG0506	proline dehydrogenase activity
JN280_RS20425	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JN280_RS20465	COG3720	iron ion transport
JN280_RS20475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JN280_RS20480	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JN280_RS20490	COG1959	2 iron, 2 sulfur cluster binding
JN280_RS20495	COG1414	Transcriptional regulator
JN280_RS20500	COG1454	alcohol dehydrogenase
JN280_RS20510	COG1137	ATPase activity
JN280_RS20535	COG3485	protocatechuate 3,4-dioxygenase
JN280_RS20545	COG0346	lactoylglutathione lyase activity
JN280_RS20570	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JN280_RS20575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JN280_RS20580	COG2814	Major facilitator Superfamily
JN280_RS20585	COG1309	transcriptional regulator
JN280_RS20630	COG2733	membrane
JN280_RS20650	COG0596	Alpha beta hydrolase
JN280_RS20650	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JN280_RS20650	COG2226	methyltransferase
JN280_RS20660	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS20685	COG1846	Transcriptional regulator
JN280_RS20690	COG0179	Fumarylacetoacetate (FAA) hydrolase
JN280_RS20695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JN280_RS20720	COG5564	TIM-barrel signal transduction protein
JN280_RS20725	COG5441	Belongs to the UPF0261 family
JN280_RS20735	COG2182	Extracellular solute-binding protein
JN280_RS20740	COG1175	transmembrane transport
JN280_RS20755	COG3842	ATPase activity
JN280_RS20760	COG3842	ATPase activity
JN280_RS20770	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JN280_RS20770	COG2755	lipolytic protein G-D-S-L family
JN280_RS20785	COG4941	Belongs to the sigma-70 factor family
JN280_RS20800	COG3795	YCII-related domain
JN280_RS20810	COG1802	Transcriptional regulator
JN280_RS20815	COG4948	Mandelate Racemase Muconate Lactonizing
JN280_RS20820	COG1082	Xylose isomerase domain protein TIM barrel
JN280_RS20830	COG0673	inositol 2-dehydrogenase activity
JN280_RS20850	COG2205	protein histidine kinase activity
JN280_RS20850	COG2198	Histidine kinase
JN280_RS20850	COG0784	Response regulator, receiver
JN280_RS20880	COG3142	Participates in the control of copper homeostasis
JN280_RS20885	COG2814	Major facilitator Superfamily
JN280_RS20890	COG1609	Transcriptional regulator
JN280_RS20900	COG0395	ABC-type sugar transport system, permease component
JN280_RS20905	COG1175	transmembrane transport
JN280_RS20910	COG3842	ATPase activity
JN280_RS20915	COG3842	ATPase activity
JN280_RS20940	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS20945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN280_RS20955	COG1024	Enoyl-CoA hydratase
JN280_RS20965	COG1012	belongs to the aldehyde dehydrogenase family
JN280_RS20970	COG1959	2 iron, 2 sulfur cluster binding
JN280_RS20975	COG1597	lipid kinase activity
JN280_RS20995	COG3842	ATPase activity
JN280_RS21005	COG1176	ABC-type spermidine putrescine transport system, permease component I
JN280_RS21015	COG2909	trisaccharide binding
JN280_RS21030	COG0411	ABC transporter
JN280_RS21045	COG4177	L-phenylalanine transmembrane transporter activity
JN280_RS21050	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JN280_RS21055	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JN280_RS21055	COG0574	Belongs to the PEP-utilizing enzyme family
JN280_RS21060	COG0517	IMP dehydrogenase activity
JN280_RS21085	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JN280_RS21105	COG3220	belongs to the UPF0276 family
JN280_RS21120	COG1595	DNA-templated transcription, initiation
JN280_RS21175	COG1921	L-seryl-tRNASec selenium transferase activity
JN280_RS21185	COG2864	formate dehydrogenase
JN280_RS21190	COG0437	4 iron, 4 sulfur cluster binding
JN280_RS21200	COG0709	Synthesizes selenophosphate from selenide and ATP
JN280_RS21205	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JN280_RS21210	COG0640	Transcriptional regulator
JN280_RS21220	COG0740	serine-type endopeptidase activity
JN280_RS21235	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JN280_RS21245	COG1525	nuclease
JN280_RS21255	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JN280_RS21260	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JN280_RS21275	COG0625	glutathione transferase activity
JN280_RS21280	COG1573	uracil-dna glycosylase
JN280_RS21285	COG1522	sequence-specific DNA binding
JN280_RS21295	COG2084	Dehydrogenase
JN280_RS21305	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS21310	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
JN280_RS21320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN280_RS21330	COG1012	belongs to the aldehyde dehydrogenase family
JN280_RS21335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JN280_RS21340	COG0427	acetyl-CoA hydrolase
JN280_RS21345	COG2188	Transcriptional regulator
JN280_RS21360	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JN280_RS21365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN280_RS21380	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS21385	COG0596	Alpha beta hydrolase
JN280_RS21400	COG1053	succinate dehydrogenase
JN280_RS21405	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS21430	COG2358	TRAP transporter, solute receptor (TAXI family
JN280_RS21450	COG1763	Mo-molybdopterin cofactor biosynthetic process
JN280_RS21455	COG0746	molybdenum cofactor guanylyltransferase activity
JN280_RS21460	COG2814	Major facilitator Superfamily
JN280_RS21480	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JN280_RS21495	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
JN280_RS21500	COG1846	Transcriptional regulator
JN280_RS21505	COG2267	carboxylic ester hydrolase activity
JN280_RS21510	COG2989	Protein conserved in bacteria
JN280_RS21525	COG0546	phosphoglycolate phosphatase activity
JN280_RS21530	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JN280_RS21550	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JN280_RS21555	COG3706	GGDEF domain
JN280_RS21565	COG3384	dioxygenase
JN280_RS21570	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JN280_RS21575	COG0586	Pfam SNARE associated Golgi protein
JN280_RS21600	COG5265	(ABC) transporter
JN280_RS21605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JN280_RS21615	COG0281	malic enzyme
JN280_RS21615	COG0280	phosphate acetyltransferase
JN280_RS21635	COG4948	Mandelate Racemase Muconate Lactonizing
JN280_RS21640	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN280_RS21645	COG1127	ABC transporter
JN280_RS21670	COG0633	Ferredoxin
JN280_RS21675	COG0492	ferredoxin-NADP+ reductase activity
JN280_RS21685	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JN280_RS21695	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JN280_RS21700	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JN280_RS21700	COG0475	glutathione-regulated potassium exporter activity
JN280_RS21725	COG3768	UPF0283 membrane protein
JN280_RS21730	COG3106	COG3106 Predicted ATPase
JN280_RS21745	COG0372	Belongs to the citrate synthase family
JN280_RS21750	COG0372	Belongs to the citrate synthase family
JN280_RS21765	COG0813	purine-nucleoside phosphorylase activity
JN280_RS21775	COG0559	Belongs to the binding-protein-dependent transport system permease family
JN280_RS21785	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JN280_RS21805	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JN280_RS21815	COG1278	Cold shock
JN280_RS21870	COG1045	serine acetyltransferase
JN280_RS21910	COG0517	IMP dehydrogenase activity
JN280_RS21910	COG0516	GMP reductase activity
JN280_RS21915	COG3811	Belongs to the UPF0386 family
JN280_RS21920	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JN280_RS21930	COG3360	Dodecin
JN280_RS21940	COG0804	urea catabolic process
JN280_RS21945	COG0832	Belongs to the urease beta subunit family
JN280_RS21950	COG0831	urea catabolic process
JN280_RS21955	COG0829	nickel cation binding
JN280_RS21960	COG0830	nickel cation binding
JN280_RS21965	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
JN280_RS21970	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JN280_RS21995	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
JN280_RS22005	COG0511	ligase activity, forming carbon-carbon bonds
JN280_RS22010	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JN280_RS22025	COG0436	Aminotransferase
JN280_RS22030	COG1530	ribonuclease E activity
JN280_RS22035	COG0860	N-Acetylmuramoyl-L-alanine amidase
JN280_RS22040	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JN280_RS22055	COG0739	heme binding
JN280_RS22060	COG2183	response to ionizing radiation
JN280_RS22085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JN280_RS22090	COG2207	Transcriptional regulator
JN280_RS22100	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JN280_RS22110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JN280_RS22115	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JN280_RS22120	COG3422	double-strand break repair
JN280_RS22130	COG2945	thiolester hydrolase activity
JN280_RS22135	COG1104	cysteine desulfurase activity
JN280_RS22140	COG0719	Fe-S assembly protein
JN280_RS22145	COG0396	ATPase activity
JN280_RS22150	COG0719	Fe-S assembly protein
JN280_RS22155	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JN280_RS22160	COG2151	metal-sulfur cluster biosynthetic enzyme
JN280_RS22165	COG0316	Belongs to the HesB IscA family
JN280_RS22170	COG3791	Glutathione-dependent formaldehyde-activating
JN280_RS22180	COG0513	Belongs to the DEAD box helicase family
JN280_RS22190	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JN280_RS22210	COG0411	ABC transporter
JN280_RS22225	COG0559	Belongs to the binding-protein-dependent transport system permease family
JN280_RS22240	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
JN280_RS22260	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JN280_RS22270	COG1414	Transcriptional regulator
JN280_RS22275	COG3960	tartronate-semialdehyde synthase activity
JN280_RS22280	COG3622	Belongs to the hyi family
JN280_RS22285	COG2084	Dehydrogenase
JN280_RS22290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JN280_RS22310	COG0129	dihydroxy-acid dehydratase activity
JN280_RS22315	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JN280_RS22330	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS22350	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JN280_RS22355	COG1802	Transcriptional regulator
JN280_RS22360	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JN280_RS22370	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JN280_RS22375	COG0081	regulation of translation
JN280_RS22380	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JN280_RS22385	COG0222	ribosome binding
JN280_RS22390	COG0085	RNA polymerase activity
JN280_RS22395	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JN280_RS22415	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JN280_RS22420	COG0049	tRNA binding
JN280_RS22425	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JN280_RS22430	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JN280_RS22440	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JN280_RS22445	COG0088	Forms part of the polypeptide exit tunnel
JN280_RS22450	COG0089	rRNA binding
JN280_RS22455	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JN280_RS22460	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JN280_RS22465	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JN280_RS22470	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JN280_RS22475	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JN280_RS22480	COG0255	Belongs to the universal ribosomal protein uL29 family
JN280_RS22485	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JN280_RS22490	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JN280_RS22495	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JN280_RS22500	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JN280_RS22505	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JN280_RS22510	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JN280_RS22515	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JN280_RS22520	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JN280_RS22525	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JN280_RS22530	COG1841	ribosomal large subunit assembly
JN280_RS22535	COG0200	Binds to the 23S rRNA
JN280_RS22545	COG0563	adenylate kinase activity
JN280_RS22550	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JN280_RS22555	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JN280_RS22560	COG0202	RNA polymerase activity
JN280_RS22565	COG0203	ribosomal protein L17
JN280_RS22570	COG3128	pkhd-type hydroxylase
JN280_RS22580	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JN280_RS22600	COG0697	spore germination
JN280_RS22610	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JN280_RS22620	COG0174	glutamine synthetase
JN280_RS22625	COG0347	Belongs to the P(II) protein family
JN280_RS22630	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JN280_RS22630	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JN280_RS22640	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JN280_RS22660	COG0784	Response regulator, receiver
JN280_RS22675	COG0582	viral genome integration into host DNA
JN280_RS22910	COG1525	nuclease
JN280_RS22935	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JN280_RS22955	COG0557	exoribonuclease II activity
JN280_RS22960	COG1754	DNA topoisomerase type I activity
JN280_RS22960	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JN280_RS22965	COG0758	DNA mediated transformation
JN280_RS22970	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JN280_RS22975	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JN280_RS22980	COG0540	Belongs to the ATCase OTCase family
JN280_RS22985	COG1960	acyl-CoA dehydrogenase activity
JN280_RS22995	COG1404	Belongs to the peptidase S8 family
JN280_RS23015	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JN280_RS23020	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JN280_RS23030	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JN280_RS23040	COG0154	amidase activity
JN280_RS23045	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JN280_RS23055	COG1760	l-serine dehydratase
JN280_RS23070	COG0484	heat shock protein binding
JN280_RS23075	COG1686	Belongs to the peptidase S11 family
JN280_RS23085	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JN280_RS23105	COG0537	adenosine 5'-monophosphoramidase activity
JN280_RS23140	COG1280	lysine exporter protein (LysE YggA)
JN280_RS23145	COG0052	Belongs to the universal ribosomal protein uS2 family
JN280_RS23150	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JN280_RS23155	COG0528	UMP kinase activity
JN280_RS23160	COG0233	cytoplasmic translational termination
JN280_RS23165	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JN280_RS23175	COG0750	zinc metalloprotease
JN280_RS23180	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JN280_RS23185	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JN280_RS23190	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JN280_RS23195	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JN280_RS23200	COG3494	Protein of unknown function (DUF1009)
JN280_RS23205	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JN280_RS23210	COG0372	Belongs to the citrate synthase family
JN280_RS23215	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JN280_RS23220	COG2333	competence protein COMEC
JN280_RS23220	COG0658	competence protein
JN280_RS23230	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JN280_RS23240	COG0303	'Molybdopterin
JN280_RS23245	COG0315	cyclic pyranopterin monophosphate synthase activity
JN280_RS23250	COG0134	indole-3-glycerol-phosphate synthase activity
JN280_RS23255	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JN280_RS23265	COG0149	triose-phosphate isomerase activity
JN280_RS23280	COG0504	CTP synthase activity
JN280_RS23285	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JN280_RS23290	COG0628	permease
JN280_RS23340	COG0583	DNA-binding transcription factor activity
JN280_RS23370	COG1686	Belongs to the peptidase S11 family
JN280_RS23375	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JN280_RS23385	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JN280_RS23390	COG0084	hydrolase, TatD family'
JN280_RS23425	COG2358	TRAP transporter, solute receptor (TAXI family
JN280_RS23440	COG4191	Histidine kinase
JN280_RS23445	COG2204	response regulator
JN280_RS23515	COG2010	Cytochrome c
JN280_RS23530	COG3278	Belongs to the heme-copper respiratory oxidase family
JN280_RS23535	COG1959	2 iron, 2 sulfur cluster binding
JN280_RS23560	COG3956	TIGRFAM MazG family protein
JN280_RS23565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JN280_RS23570	COG1923	regulation of RNA biosynthetic process
JN280_RS23575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JN280_RS23580	COG0569	domain protein
JN280_RS23585	COG2204	response regulator
JN280_RS23590	COG5000	phosphorelay sensor kinase activity
JN280_RS23600	COG2204	response regulator
JN280_RS23605	COG3852	Histidine kinase
JN280_RS23615	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JN280_RS23615	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JN280_RS23630	COG1942	4-Oxalocrotonate Tautomerase
JN280_RS23645	COG1733	regulation of RNA biosynthetic process
JN280_RS23680	COG2867	negative regulation of translational initiation
JN280_RS23685	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JN280_RS23695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JN280_RS23710	COG0508	dehydrogenase complex catalyzes the overall conversion of
JN280_RS23715	COG0508	dehydrogenase complex catalyzes the overall conversion of
JN280_RS23715	COG0022	dehydrogenase e1 component
JN280_RS23720	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JN280_RS23725	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JN280_RS23730	COG0148	phosphopyruvate hydratase activity
JN280_RS23750	COG2877	3-deoxy-8-phosphooctulonate synthase activity
JN280_RS23760	COG0861	Integral membrane protein TerC family
JN280_RS23765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JN280_RS23780	COG1079	Belongs to the binding-protein-dependent transport system permease family
JN280_RS23785	COG4603	Belongs to the binding-protein-dependent transport system permease family
JN280_RS23790	COG3845	ABC transporter
JN280_RS23800	COG1183	phosphatidylcholine synthase activity
JN280_RS23815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN280_RS23820	COG0679	Auxin Efflux Carrier
JN280_RS23850	COG0583	DNA-binding transcription factor activity
JN280_RS23855	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JN280_RS23865	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JN280_RS23875	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JN280_RS23880	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JN280_RS23885	COG0785	Cytochrome C biogenesis protein
JN280_RS23895	COG0494	nUDIX hydrolase
JN280_RS23905	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JN280_RS23920	COG0395	ABC-type sugar transport system, permease component
JN280_RS23935	COG3842	ATPase activity
JN280_RS23950	COG0747	negative chemotaxis
JN280_RS23955	COG0601	transmembrane transport
JN280_RS23960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN280_RS23965	COG4172	Belongs to the ABC transporter superfamily
JN280_RS24005	COG2308	Evidence 4 Homologs of previously reported genes of
JN280_RS24020	COG0343	queuine tRNA-ribosyltransferase activity
JN280_RS24030	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JN280_RS24045	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JN280_RS24060	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JN280_RS24080	COG2095	MarC family integral membrane protein
JN280_RS24090	COG0629	single-stranded DNA binding
JN280_RS24100	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JN280_RS24115	COG0697	spore germination
JN280_RS24120	COG0730	response to heat
JN280_RS24135	COG4770	biotin carboxylase activity
JN280_RS24140	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
JN280_RS24145	COG1671	Belongs to the UPF0178 family
JN280_RS24155	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JN280_RS24160	COG0509	glycine decarboxylation via glycine cleavage system
JN280_RS24165	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JN280_RS24165	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JN280_RS24170	COG0187	DNA topoisomerase II activity
JN280_RS24185	COG2301	Belongs to the HpcH HpaI aldolase family
JN280_RS24190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JN280_RS24205	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JN280_RS24210	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JN280_RS24220	COG0583	DNA-binding transcription factor activity
JN280_RS24230	COG0302	gtp cyclohydrolase
JN280_RS24235	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JN280_RS24240	COG1752	Esterase of the alpha-beta hydrolase superfamily
JN280_RS24250	COG1494	fructose-1,6-bisphosphatase
JN280_RS24260	COG0436	Aminotransferase
JN280_RS24270	COG3243	poly(R)-hydroxyalkanoic acid synthase
JN280_RS24330	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JN280_RS24335	COG3189	MarR family transcriptional regulator
JN280_RS24355	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JN280_RS24375	COG0583	DNA-binding transcription factor activity
JN280_RS24380	COG0784	Response regulator, receiver
JN280_RS24380	COG4191	Histidine kinase
JN280_RS24390	COG0784	Response regulator, receiver
JN280_RS24390	COG4191	Histidine kinase
JN280_RS24420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JN280_RS24435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JN280_RS24450	COG0446	pyridine nucleotide-disulphide oxidoreductase
JN280_RS24470	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JN280_RS24520	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JN280_RS24545	COG1063	alcohol dehydrogenase
JN280_RS24550	COG0156	8-amino-7-oxononanoate synthase activity
JN280_RS24555	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JN280_RS24570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN280_RS24575	COG0601	transmembrane transport
JN280_RS24590	COG1120	ATPase activity
JN280_RS24595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JN280_RS24620	COG1522	sequence-specific DNA binding
JN280_RS24625	COG2171	N-acyltransferase activity
JN280_RS24635	COG1012	belongs to the aldehyde dehydrogenase family
JN280_RS24640	COG0473	3-isopropylmalate dehydrogenase activity
JN280_RS24655	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JN280_RS24775	COG4964	Belongs to the GSP D family
JN280_RS24860	COG3300	MHYT domain
JN280_RS24860	COG5001	Diguanylate cyclase
JN280_RS24865	COG0024	Methionine aminopeptidase
JN280_RS24870	COG2003	Belongs to the UPF0758 family
JN280_RS24880	COG1349	DNA-binding transcription factor activity
JN280_RS24885	COG3119	arylsulfatase activity
JN280_RS24900	COG0544	peptidyl-prolyl cis-trans isomerase activity
JN280_RS24935	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JN280_RS24940	COG1024	Enoyl-CoA hydratase
JN280_RS24970	COG1862	Preprotein translocase
JN280_RS24990	COG1473	amidohydrolase
JN280_RS25000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN280_RS25005	COG0601	transmembrane transport
JN280_RS25010	COG0747	negative chemotaxis
JN280_RS25025	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JN280_RS25030	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JN280_RS25035	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JN280_RS25040	COG0805	protein transport
JN280_RS25045	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JN280_RS25050	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JN280_RS25055	COG3842	ATPase activity
JN280_RS25060	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JN280_RS25065	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JN280_RS25080	COG0018	arginyl-trna synthetase
JN280_RS25085	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JN280_RS25095	COG2233	PERMEase
JN280_RS25100	COG0708	Exodeoxyribonuclease III
JN280_RS25105	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
JN280_RS25110	COG0129	dihydroxy-acid dehydratase activity
JN280_RS25115	COG0525	valine-tRNA ligase activity
JN280_RS25130	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JN280_RS25540	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
JN280_RS25540	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JN280_RS25705	COG0305	Participates in initiation and elongation during chromosome replication
JN280_RS25790	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JN280_RS25825	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
JN280_RS25845	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JN280_RS25915	COG4957	zinc ion binding
JN280_RS25975	COG1715	Restriction endonuclease
JN280_RS25980	COG0732	type I restriction modification DNA specificity domain
JN280_RS25990	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
JN280_RS26005	COG1993	acr, cog1993
JN280_RS26010	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JN280_RS26015	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JN280_RS26065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JN280_RS26070	COG0625	glutathione transferase activity
JN280_RS26075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN280_RS26080	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
JN280_RS26085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JN280_RS26110	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JN280_RS26140	COG2010	Cytochrome c
JN280_RS26180	COG3264	Mechanosensitive ion channel
JN280_RS26180	COG1511	domain protein
JN280_RS26205	COG3118	belongs to the thioredoxin family
JN280_RS26225	COG0842	Transport permease protein
JN280_RS26230	COG1131	(ABC) transporter
JN280_RS26235	COG1129	ABC transporter
JN280_RS26255	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS26275	COG1960	acyl-CoA dehydrogenase activity
JN280_RS26280	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS26320	COG1960	acyl-CoA dehydrogenase activity
JN280_RS26325	COG1024	Enoyl-CoA hydratase
JN280_RS26345	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JN280_RS26365	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JN280_RS26370	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JN280_RS26380	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JN280_RS26385	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JN280_RS26430	COG0456	acetyltransferase
JN280_RS26435	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN280_RS26445	COG0737	Belongs to the 5'-nucleotidase family
JN280_RS26455	COG1252	NADH dehydrogenase
JN280_RS26465	COG0686	Belongs to the AlaDH PNT family
JN280_RS26485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN280_RS26510	COG2897	thiosulfate sulfurtransferase activity
JN280_RS26515	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JN280_RS26525	COG0300	oxidoreductase activity
JN280_RS26540	COG0513	Belongs to the DEAD box helicase family
JN280_RS26550	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JN280_RS26555	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JN280_RS26565	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JN280_RS26600	COG1960	acyl-CoA dehydrogenase activity
JN280_RS26620	COG0508	dehydrogenase complex catalyzes the overall conversion of
JN280_RS26620	COG0596	Alpha beta hydrolase
JN280_RS26625	COG0655	NAD(P)H dehydrogenase (quinone) activity
JN280_RS26630	COG1058	Belongs to the CinA family
JN280_RS26630	COG1546	Belongs to the CinA family
JN280_RS26640	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
JN280_RS26650	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JN280_RS26680	COG1902	pentaerythritol trinitrate reductase activity
JN280_RS26690	COG1653	transport
JN280_RS26700	COG1175	transmembrane transport
JN280_RS26705	COG0395	ABC-type sugar transport system, permease component
JN280_RS26710	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JN280_RS26850	COG0631	protein serine/threonine phosphatase activity
JN280_RS26875	COG0811	peptide transport
JN280_RS26890	COG0739	heme binding
JN280_RS26895	COG2885	chlorophyll binding
JN280_RS26920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN280_RS26930	COG0583	DNA-binding transcription factor activity
JN280_RS26945	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
JN280_RS26950	COG3791	Glutathione-dependent formaldehyde-activating
JN280_RS26970	COG1653	transport
JN280_RS26975	COG1175	transmembrane transport
JN280_RS26985	COG3842	ATPase activity
JN280_RS26990	COG1609	Transcriptional regulator
JN280_RS27005	COG1129	ABC transporter
JN280_RS27010	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS27015	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS27020	COG3265	gluconokinase activity
JN280_RS27035	COG1959	2 iron, 2 sulfur cluster binding
JN280_RS27050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JN280_RS27060	COG0586	Pfam SNARE associated Golgi protein
JN280_RS27065	COG1595	DNA-templated transcription, initiation
JN280_RS27085	COG0583	DNA-binding transcription factor activity
JN280_RS27090	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JN280_RS27115	COG0019	diaminopimelate decarboxylase activity
JN280_RS27130	COG1280	lysine exporter protein (LysE YggA)
JN280_RS27135	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JN280_RS27140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN280_RS27170	COG0667	Aldo Keto reductase
JN280_RS27215	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JN280_RS27220	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JN280_RS27220	COG3608	succinylglutamate desuccinylase aspartoacylase
JN280_RS27240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JN280_RS27245	COG0683	leucine binding
JN280_RS27250	COG3191	aminopeptidase activity
JN280_RS27265	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JN280_RS27270	COG2514	catechol 2,3-dioxygenase activity
JN280_RS27290	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JN280_RS27295	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JN280_RS27320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JN280_RS27335	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JN280_RS27345	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS27355	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS27365	COG4948	Mandelate Racemase Muconate Lactonizing
JN280_RS27370	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS27385	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JN280_RS27395	COG0483	inositol monophosphate 1-phosphatase activity
JN280_RS27400	COG0037	tRNA processing
JN280_RS27405	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JN280_RS27415	COG1733	regulation of RNA biosynthetic process
JN280_RS27420	COG2910	NAD(P)H-binding
JN280_RS27425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JN280_RS27445	COG0596	Alpha beta hydrolase
JN280_RS27450	COG0538	isocitrate dehydrogenase activity
JN280_RS27465	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JN280_RS27470	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JN280_RS27475	COG2885	chlorophyll binding
JN280_RS27505	COG2239	Acts as a magnesium transporter
JN280_RS27510	COG1278	Cold shock
JN280_RS27515	COG1032	radical SAM domain protein
JN280_RS27545	COG0321	lipoyl(octanoyl) transferase activity
JN280_RS27550	COG0405	Gamma-glutamyltransferase
JN280_RS27555	COG1136	(ABC) transporter
JN280_RS27565	COG0442	prolyl-tRNA aminoacylation
JN280_RS27580	COG0346	lactoylglutathione lyase activity
JN280_RS27595	COG1007	ATP synthesis coupled electron transport
JN280_RS27610	COG0713	ATP synthesis coupled electron transport
JN280_RS27620	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JN280_RS27630	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JN280_RS27640	COG3743	rRNA binding
JN280_RS27640	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JN280_RS27645	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
JN280_RS27650	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
JN280_RS27655	COG0649	NAD binding
JN280_RS27665	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JN280_RS27720	COG0776	regulation of translation
JN280_RS27730	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JN280_RS27735	COG0740	serine-type endopeptidase activity
JN280_RS27745	COG2124	cytochrome p450
JN280_RS27760	COG0798	PFAM Bile acid sodium symporter
JN280_RS27770	COG0431	NADPH-dependent FMN reductase
JN280_RS27800	COG1832	CoA-binding protein
JN280_RS27815	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JN280_RS27820	COG0446	pyridine nucleotide-disulphide oxidoreductase
JN280_RS27835	COG1609	Transcriptional regulator
JN280_RS27840	COG1414	Transcriptional regulator
JN280_RS27865	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JN280_RS27875	COG1309	transcriptional regulator
JN280_RS27880	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JN280_RS27890	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JN280_RS27895	COG0673	inositol 2-dehydrogenase activity
JN280_RS27900	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JN280_RS27905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JN280_RS27910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JN280_RS27915	COG0531	amino acid
JN280_RS27960	COG0584	glycerophosphoryl diester phosphodiesterase
JN280_RS27965	COG0010	Belongs to the arginase family
JN280_RS27970	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JN280_RS27975	COG1612	heme a metabolic process
JN280_RS27995	COG2801	Transposase and inactivated derivatives
JN280_RS28015	COG0438	transferase activity, transferring glycosyl groups
JN280_RS28055	COG0776	regulation of translation
JN280_RS28060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JN280_RS28065	COG0416	fatty acid biosynthetic process
JN280_RS28080	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JN280_RS28085	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
JN280_RS28090	COG1174	glycine betaine transport
JN280_RS28095	COG1125	glycine betaine transport
JN280_RS28100	COG1174	glycine betaine transport
JN280_RS28105	COG1732	Glycine betaine
JN280_RS28110	COG2814	Major facilitator Superfamily
JN280_RS28115	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JN280_RS28130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JN280_RS28130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JN280_RS28140	COG2814	Major facilitator Superfamily
JN280_RS28145	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JN280_RS28165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JN280_RS28170	COG2989	Protein conserved in bacteria
JN280_RS28185	COG1024	Enoyl-CoA hydratase
JN280_RS28190	COG0113	porphobilinogen synthase activity
JN280_RS28210	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
JN280_RS28225	COG0628	permease
JN280_RS28275	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JN280_RS28290	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JN280_RS28305	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
JN280_RS28310	COG0248	Ppx GppA phosphatase
JN280_RS28315	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JN280_RS28330	COG1126	abc transporter atp-binding protein
JN280_RS28335	COG0765	amino acid transport
JN280_RS28340	COG4597	amino acid ABC transporter
JN280_RS28345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN280_RS28350	COG0671	phosphoesterase, PA-phosphatase related
JN280_RS28355	COG0626	cystathionine gamma-synthase activity
JN280_RS28375	COG1696	Membrane protein involved in D-alanine export
JN280_RS28395	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JN280_RS28440	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JN280_RS28470	COG0628	permease
JN280_RS28480	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JN280_RS28485	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JN280_RS28495	COG0243	molybdopterin cofactor binding
JN280_RS28500	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
JN280_RS28515	COG0625	glutathione transferase activity
JN280_RS28530	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS28535	COG0322	excinuclease ABC activity
JN280_RS28540	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JN280_RS28550	COG0314	molybdopterin synthase activity
JN280_RS28555	COG3126	Type III secretion system lipoprotein chaperone (YscW)
JN280_RS28565	COG0105	UTP biosynthetic process
JN280_RS28580	COG0488	(ABC) transporter
JN280_RS28610	COG0670	Belongs to the BI1 family
JN280_RS28635	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JN280_RS28640	COG0671	phosphoesterase, PA-phosphatase related
JN280_RS28660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JN280_RS28665	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JN280_RS28670	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JN280_RS28675	COG0194	GDP metabolic process
JN280_RS28680	COG1561	YicC-like family, N-terminal region
JN280_RS28685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JN280_RS28690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JN280_RS28695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JN280_RS28705	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JN280_RS28715	COG0360	Binds together with S18 to 16S ribosomal RNA
JN280_RS28725	COG0359	binds to the 23S rRNA
JN280_RS28730	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN280_RS28735	COG1742	UPF0060 membrane protein
JN280_RS28755	COG0305	Participates in initiation and elongation during chromosome replication
JN280_RS28770	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JN280_RS28775	COG4221	oxidoreductase activity
JN280_RS28810	COG1183	phosphatidylcholine synthase activity
JN280_RS28815	COG0688	phosphatidylethanolamine metabolic process
JN280_RS28820	COG5265	(ABC) transporter
JN280_RS28845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JN280_RS28870	COG2852	Protein conserved in bacteria
JN280_RS28910	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JN280_RS28915	COG0354	folic acid binding
JN280_RS28920	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
JN280_RS28935	COG4721	ABC-type cobalt transport system, permease component
JN280_RS28940	COG1122	ATPase activity
JN280_RS28945	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JN280_RS28965	COG1595	DNA-templated transcription, initiation
JN280_RS28985	COG1733	regulation of RNA biosynthetic process
JN280_RS29000	COG1381	Involved in DNA repair and RecF pathway recombination
JN280_RS29015	COG0420	3'-5' exonuclease activity
JN280_RS29020	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JN280_RS29025	COG0571	ribonuclease III activity
JN280_RS29030	COG0681	Belongs to the peptidase S26 family
JN280_RS29035	COG0736	holo-[acyl-carrier-protein] synthase activity
JN280_RS29040	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JN280_RS29050	COG1758	RNA polymerase activity
JN280_RS29060	COG1573	uracil-dna glycosylase
JN280_RS29065	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JN280_RS29070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JN280_RS29075	COG0668	transmembrane transport
JN280_RS29080	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JN280_RS29085	COG0741	lytic transglycosylase activity
JN280_RS29110	COG1216	Glycosyl transferase, family 2
JN280_RS29115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JN280_RS29150	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN280_RS29160	COG1696	Membrane protein involved in D-alanine export
JN280_RS29165	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JN280_RS29165	COG0463	Glycosyl transferase, family 2
JN280_RS29185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JN280_RS29195	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JN280_RS29210	COG1254	Belongs to the acylphosphatase family
JN280_RS29230	COG2273	Hydrolase Family 16
JN280_RS29230	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
JN280_RS29240	COG1960	acyl-CoA dehydrogenase activity
JN280_RS29245	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JN280_RS29250	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JN280_RS29270	COG0625	glutathione transferase activity
JN280_RS29285	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JN280_RS29315	COG1573	uracil-dna glycosylase
JN280_RS29335	COG2226	methyltransferase
JN280_RS29360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JN280_RS29365	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JN280_RS29375	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JN280_RS29380	COG1396	sequence-specific DNA binding
JN280_RS29405	COG0395	ABC-type sugar transport system, permease component
JN280_RS29410	COG1175	transmembrane transport
JN280_RS29415	COG3842	ATPase activity
JN280_RS29510	COG4178	(ABC) transporter
JN280_RS29515	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JN280_RS29535	COG0308	aminopeptidase N
JN280_RS29540	COG2205	protein histidine kinase activity
JN280_RS29540	COG2202	Pas domain
JN280_RS29545	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JN280_RS29550	COG2205	protein histidine kinase activity
JN280_RS29560	COG0745	RESPONSE REGULATOR receiver
JN280_RS29565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JN280_RS29570	COG3088	subunit of a heme lyase
JN280_RS29575	COG1138	Cytochrome C-type biogenesis protein
JN280_RS29580	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
JN280_RS29585	COG4235	cytochrome complex assembly
JN280_RS29590	COG3474	cytochrome
JN280_RS29610	COG1063	alcohol dehydrogenase
JN280_RS29650	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JN280_RS29675	COG1228	amidohydrolase
JN280_RS29680	COG1686	Belongs to the peptidase S11 family
JN280_RS29685	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JN280_RS29730	COG2205	protein histidine kinase activity
JN280_RS29740	COG2166	iron-sulfur cluster assembly
JN280_RS29750	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JN280_RS29770	COG0477	Major facilitator Superfamily
JN280_RS29775	COG2010	Cytochrome c
JN280_RS29780	COG3909	cytochrome
JN280_RS29785	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JN280_RS29800	COG1376	ErfK ybiS ycfS ynhG family protein
JN280_RS29805	COG0433	COG0433 Predicted ATPase
JN280_RS29825	COG3654	unkown
JN280_RS29845	COG0667	Aldo Keto reductase
JN280_RS29850	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS29855	COG0183	Belongs to the thiolase family
JN280_RS29860	COG1309	transcriptional regulator
JN280_RS29865	COG3119	arylsulfatase activity
JN280_RS29875	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
JN280_RS29880	COG1012	belongs to the aldehyde dehydrogenase family
JN280_RS29900	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
JN280_RS29910	COG1877	trehalose-phosphatase activity
JN280_RS29915	COG0366	Alpha amylase catalytic
JN280_RS29920	COG1523	belongs to the glycosyl hydrolase 13 family
JN280_RS29925	COG0033	Phosphoglucomutase
JN280_RS29930	COG0297	glycogen (starch) synthase activity
JN280_RS29935	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JN280_RS29940	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JN280_RS29945	COG0058	SHG alpha-glucan phosphorylase activity
JN280_RS29985	COG3547	Transposase (IS116 IS110 IS902 family)
JN280_RS29990	COG1218	3'(2'),5'-bisphosphate nucleotidase
JN280_RS30000	COG0175	sulfate reduction
JN280_RS30005	COG1090	epimerase
JN280_RS30020	COG1744	ABC transporter substrate-binding protein PnrA-like
JN280_RS30025	COG3845	ABC transporter
JN280_RS30030	COG4603	Belongs to the binding-protein-dependent transport system permease family
JN280_RS30040	COG0402	S-adenosylhomocysteine deaminase activity
JN280_RS30055	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS30060	COG2252	PERMEase
JN280_RS30070	COG1115	amino acid carrier protein
JN280_RS30075	COG0252	asparaginase activity
JN280_RS30100	COG2721	sulfolactate sulfo-lyase activity
JN280_RS30105	COG1879	ABC-type sugar transport system periplasmic component
JN280_RS30110	COG1129	ABC transporter
JN280_RS30115	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS30120	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS30150	COG1268	BioY protein
JN280_RS30185	COG0297	glycogen (starch) synthase activity
JN280_RS30190	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JN280_RS30190	COG0574	Belongs to the PEP-utilizing enzyme family
JN280_RS30205	COG1196	nuclear chromosome segregation
JN280_RS30210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JN280_RS30230	COG2189	Belongs to the N(4) N(6)-methyltransferase family
JN280_RS30235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JN280_RS30240	COG0861	Integral membrane protein TerC family
JN280_RS30255	COG0612	Peptidase, M16
JN280_RS30260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JN280_RS30265	COG5001	Diguanylate cyclase
JN280_RS30265	COG3300	MHYT domain
JN280_RS30270	COG1678	Uncharacterized ACR, COG1678
JN280_RS30280	COG0678	peroxiredoxin activity
JN280_RS30280	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JN280_RS30285	COG0328	RNA-DNA hybrid ribonuclease activity
JN280_RS30290	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JN280_RS30295	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JN280_RS30305	COG0312	modulator of DNA gyrase
JN280_RS30315	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JN280_RS30315	COG1565	acr, cog1565
JN280_RS30320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JN280_RS30325	COG0109	protoheme IX farnesyltransferase activity
JN280_RS30335	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
JN280_RS30350	COG3346	SURF1 family
JN280_RS30375	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JN280_RS30400	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
JN280_RS30415	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JN280_RS30420	COG1741	Belongs to the pirin family
JN280_RS30425	COG1722	exodeoxyribonuclease VII activity
JN280_RS30430	COG0123	including yeast histone deacetylase and acetoin utilization protein
JN280_RS30435	COG0778	Nitroreductase
JN280_RS30445	COG0583	DNA-binding transcription factor activity
JN280_RS30450	COG0625	glutathione transferase activity
JN280_RS30460	COG1309	transcriptional regulator
JN280_RS30475	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JN280_RS30475	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JN280_RS30480	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JN280_RS30485	COG0778	Nitroreductase
JN280_RS30495	COG0406	alpha-ribazole phosphatase activity
JN280_RS30500	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JN280_RS30505	COG0484	heat shock protein binding
JN280_RS30515	COG0259	pyridoxamine-phosphate oxidase activity
JN280_RS30525	COG1024	Enoyl-CoA hydratase
JN280_RS30530	COG1960	acyl-CoA dehydrogenase activity
JN280_RS30540	COG0151	Belongs to the GarS family
JN280_RS30545	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JN280_RS30555	COG0277	FAD linked oxidase domain protein
JN280_RS30560	COG0009	L-threonylcarbamoyladenylate synthase
JN280_RS30575	COG0751	glycine-tRNA ligase activity
JN280_RS30580	COG0752	glycyl-tRNA synthetase alpha subunit
JN280_RS30595	COG0142	geranyltranstransferase activity
JN280_RS30625	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JN280_RS30630	COG0521	Mo-molybdopterin cofactor biosynthetic process
JN280_RS30645	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JN280_RS30660	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JN280_RS30665	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JN280_RS30670	COG0356	it plays a direct role in the translocation of protons across the membrane
JN280_RS30705	COG2205	protein histidine kinase activity
JN280_RS30725	COG1160	GTP binding
JN280_RS30730	COG2976	Protein conserved in bacteria
JN280_RS30745	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
JN280_RS30750	COG0477	Major facilitator Superfamily
JN280_RS30760	COG0583	DNA-binding transcription factor activity
JN280_RS30765	COG2309	aminopeptidase activity
JN280_RS30770	COG1393	Belongs to the ArsC family
JN280_RS30785	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JN280_RS30795	COG4208	sulfate ABC transporter
JN280_RS30800	COG3842	ATPase activity
JN280_RS30825	COG1132	(ABC) transporter
JN280_RS30830	COG3842	ATPase activity
JN280_RS30835	COG0395	ABC-type sugar transport system, permease component
JN280_RS30840	COG1175	transmembrane transport
JN280_RS30845	COG1653	transport
JN280_RS30850	COG1879	ABC-type sugar transport system periplasmic component
JN280_RS30855	COG1129	ABC transporter
JN280_RS30860	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS30865	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS30870	COG1609	Transcriptional regulator
JN280_RS30890	COG0174	glutamine synthetase
JN280_RS30905	COG1535	isochorismatase
JN280_RS30905	COG3433	isochorismatase activity
JN280_RS30910	COG0683	leucine binding
JN280_RS30925	COG0559	Belongs to the binding-protein-dependent transport system permease family
JN280_RS30935	COG1335	isochorismatase
JN280_RS30945	COG5507	3-demethylubiquinone-9 3-methyltransferase
JN280_RS30970	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JN280_RS30975	COG3842	ATPase activity
JN280_RS30980	COG0395	ABC-type sugar transport system, permease component
JN280_RS30995	COG0667	Aldo Keto reductase
JN280_RS31005	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
JN280_RS31020	COG0330	HflC and HflK could
JN280_RS31030	COG0488	(ABC) transporter
JN280_RS31045	COG0242	peptide deformylase activity
JN280_RS31055	COG4941	Belongs to the sigma-70 factor family
JN280_RS31060	COG3795	YCII-related domain
JN280_RS31075	COG0514	ATP-dependent DNA helicase (RecQ)
JN280_RS31080	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JN280_RS31090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JN280_RS31095	COG0183	Belongs to the thiolase family
JN280_RS31100	COG1960	acyl-CoA dehydrogenase activity
JN280_RS31185	COG1222	aaa ATPase
JN280_RS31215	COG4952	isomerase
JN280_RS31220	COG3347	Dehydrogenase
JN280_RS31220	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS31225	COG1349	DNA-binding transcription factor activity
JN280_RS31235	COG1129	ABC transporter
JN280_RS31285	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JN280_RS31295	COG4948	Mandelate Racemase Muconate Lactonizing
JN280_RS31300	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS31305	COG1063	alcohol dehydrogenase
JN280_RS31335	COG4977	sequence-specific DNA binding
JN280_RS31355	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JN280_RS31355	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JN280_RS31370	COG4269	membrane
JN280_RS31375	COG4783	chaperone-mediated protein folding
JN280_RS31380	COG0477	Major facilitator Superfamily
JN280_RS31385	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
JN280_RS31490	COG0583	DNA-binding transcription factor activity
JN280_RS31495	COG3585	molybdate ion transport
JN280_RS31495	COG2005	Transcriptional regulator
JN280_RS31500	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JN280_RS31505	COG4149	molybdate abc transporter
JN280_RS31510	COG0725	ABC transporter, periplasmic molybdate-binding protein
JN280_RS31515	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JN280_RS31520	COG2855	membrane
JN280_RS31525	COG0583	DNA-binding transcription factor activity
JN280_RS31530	COG1956	GAF domain-containing protein
JN280_RS31535	COG0494	nUDIX hydrolase
JN280_RS31545	COG2186	Transcriptional regulator
JN280_RS31550	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS31555	COG1129	ABC transporter
JN280_RS31570	COG1129	ABC transporter
JN280_RS31575	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS31590	COG0625	glutathione transferase activity
JN280_RS31615	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
JN280_RS31625	COG0402	S-adenosylhomocysteine deaminase activity
JN280_RS31635	COG0251	oxidation-reduction process
JN280_RS31650	COG1121	(ABC) transporter
JN280_RS31655	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JN280_RS31660	COG0803	Belongs to the bacterial solute-binding protein 9 family
JN280_RS31670	COG0523	cobalamin synthesis protein
JN280_RS31680	COG1024	Enoyl-CoA hydratase
JN280_RS31680	COG1250	3-hydroxyacyl-CoA dehydrogenase
JN280_RS31685	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS31690	COG0183	Belongs to the thiolase family
JN280_RS31695	COG1960	acyl-CoA dehydrogenase activity
JN280_RS31700	COG1960	acyl-CoA dehydrogenase activity
JN280_RS31730	COG1846	Transcriptional regulator
JN280_RS31745	COG1063	alcohol dehydrogenase
JN280_RS31750	COG0156	8-amino-7-oxononanoate synthase activity
JN280_RS31755	COG1960	acyl-CoA dehydrogenase activity
JN280_RS31760	COG2945	thiolester hydrolase activity
JN280_RS31795	COG0697	spore germination
JN280_RS31810	COG2080	2 iron, 2 sulfur cluster binding
JN280_RS31815	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JN280_RS31820	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JN280_RS31830	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS31835	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS31845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JN280_RS31850	COG0747	negative chemotaxis
JN280_RS31855	COG0444	Belongs to the ABC transporter superfamily
JN280_RS31860	COG4608	Belongs to the ABC transporter superfamily
JN280_RS31870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN280_RS31885	COG1309	transcriptional regulator
JN280_RS31895	COG4591	ABC-type transport system involved in lipoprotein release permease component
JN280_RS31900	COG1136	(ABC) transporter
JN280_RS31915	COG0189	ligase activity
JN280_RS31935	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JN280_RS31940	COG2271	Major facilitator Superfamily
JN280_RS31955	COG0583	DNA-binding transcription factor activity
JN280_RS31995	COG1733	regulation of RNA biosynthetic process
JN280_RS32000	COG1733	regulation of RNA biosynthetic process
JN280_RS32020	COG2824	Alkylphosphonate utilization operon protein PhnA
JN280_RS32025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JN280_RS32035	COG1280	lysine exporter protein (LysE YggA)
JN280_RS32040	COG3842	ATPase activity
JN280_RS32050	COG0673	inositol 2-dehydrogenase activity
JN280_RS32055	COG0395	ABC-type sugar transport system, permease component
JN280_RS32060	COG1175	transmembrane transport
JN280_RS32070	COG1802	Transcriptional regulator
JN280_RS32075	COG5441	Belongs to the UPF0261 family
JN280_RS32080	COG5564	TIM-barrel signal transduction protein
JN280_RS32085	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JN280_RS32125	COG0667	Aldo Keto reductase
JN280_RS32130	COG0583	DNA-binding transcription factor activity
JN280_RS32140	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JN280_RS32145	COG0583	DNA-binding transcription factor activity
JN280_RS32155	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS32190	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JN280_RS32225	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JN280_RS32245	COG0579	oxidoreductase
JN280_RS32250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JN280_RS32280	COG1024	Enoyl-CoA hydratase
JN280_RS32315	COG1663	tetraacyldisaccharide 4'-kinase activity
JN280_RS32320	COG1519	Transferase
JN280_RS32340	COG0312	modulator of DNA gyrase
JN280_RS32345	COG0475	glutathione-regulated potassium exporter activity
JN280_RS32345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JN280_RS32355	COG0488	(ABC) transporter
JN280_RS32375	COG0741	lytic transglycosylase activity
JN280_RS32390	COG0612	Peptidase, M16
JN280_RS32395	COG0612	Peptidase, M16
JN280_RS32400	COG0742	ribosomal rna small subunit methyltransferase
JN280_RS32410	COG0590	tRNA wobble adenosine to inosine editing
JN280_RS32420	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JN280_RS32430	COG0196	riboflavin kinase activity
JN280_RS32445	COG1280	lysine exporter protein (LysE YggA)
JN280_RS32450	COG2814	Major facilitator Superfamily
JN280_RS32455	COG1566	PFAM secretion protein HlyD family protein
JN280_RS32460	COG1846	Transcriptional regulator
JN280_RS32465	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JN280_RS32470	COG0459	protein refolding
JN280_RS32495	COG0124	histidyl-tRNA synthetase
JN280_RS32500	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JN280_RS32505	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JN280_RS32515	COG0114	fumarate hydratase activity
JN280_RS32520	COG2818	Glycosylase
JN280_RS32525	COG1376	ErfK ybiS ycfS ynhG family protein
JN280_RS32540	COG0247	lactate metabolic process
JN280_RS32560	COG0277	FAD linked oxidase domain protein
JN280_RS32565	COG2186	Transcriptional regulator
JN280_RS32570	COG0247	lactate metabolic process
JN280_RS32575	COG1304	FMN binding
JN280_RS32620	COG0583	DNA-binding transcription factor activity
JN280_RS32635	COG1570	exodeoxyribonuclease VII activity
JN280_RS32660	COG0402	S-adenosylhomocysteine deaminase activity
JN280_RS32670	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JN280_RS32675	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JN280_RS32680	COG1802	Transcriptional regulator
JN280_RS32700	COG5490	Phasin protein
JN280_RS32705	COG2205	protein histidine kinase activity
JN280_RS32710	COG0326	Molecular chaperone. Has ATPase activity
JN280_RS32715	COG1840	ABC-type Fe3 transport system, periplasmic component
JN280_RS32720	COG1178	ABC-type Fe3 transport system permease component
JN280_RS32725	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JN280_RS32735	COG1177	transmembrane transport
JN280_RS32740	COG1176	ABC-type spermidine putrescine transport system, permease component I
JN280_RS32745	COG3842	ATPase activity
JN280_RS32755	COG0174	glutamine synthetase
JN280_RS32770	COG1396	sequence-specific DNA binding
JN280_RS32770	COG3800	Transcriptional regulator
JN280_RS32775	COG2224	Isocitrate lyase
JN280_RS32790	COG0174	glutamine synthetase
JN280_RS32795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN280_RS32800	COG0110	maltose O-acetyltransferase activity
JN280_RS32815	COG1012	belongs to the aldehyde dehydrogenase family
JN280_RS32820	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JN280_RS32825	COG0363	glucosamine-6-phosphate deaminase activity
JN280_RS32830	COG0129	dihydroxy-acid dehydratase activity
JN280_RS32850	COG1960	acyl-CoA dehydrogenase activity
JN280_RS32865	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JN280_RS32885	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JN280_RS32910	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
JN280_RS32925	COG0840	transmembrane signaling receptor activity
JN280_RS32930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN280_RS32945	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JN280_RS32955	COG0765	amino acid transport
JN280_RS32970	COG1176	ABC-type spermidine putrescine transport system, permease component I
JN280_RS32975	COG3842	ATPase activity
JN280_RS33000	COG0604	alcohol dehydrogenase
JN280_RS33020	COG1181	Belongs to the D-alanine--D-alanine ligase family
JN280_RS33025	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JN280_RS33040	COG2022	thiamine diphosphate biosynthetic process
JN280_RS33050	COG0351	phosphomethylpyrimidine kinase
JN280_RS33085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JN280_RS33095	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JN280_RS33100	COG5328	Belongs to the UPF0262 family
JN280_RS33110	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JN280_RS33115	COG0424	maF-like protein
JN280_RS33120	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
JN280_RS33130	COG0582	viral genome integration into host DNA
JN280_RS33155	COG3177	Filamentation induced by cAMP protein fic
JN280_RS33185	COG2010	Cytochrome c
JN280_RS33215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JN280_RS33225	COG2948	multi-organism process
JN280_RS33250	COG3451	type IV secretory pathway VirB4
JN280_RS33260	COG3838	Conjugal transfer protein Trbc
JN280_RS33265	COG4962	Type ii secretion system protein e
JN280_RS33295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JN280_RS33310	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JN280_RS33315	COG3916	Acyl-homoserine-lactone synthase
JN280_RS33335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JN280_RS33345	COG1278	Cold shock
JN280_RS33355	COG1304	FMN binding
JN280_RS33365	COG1657	PFAM Prenyltransferase squalene oxidase
JN280_RS33370	COG0142	geranyltranstransferase activity
JN280_RS33375	COG2124	cytochrome p450
JN280_RS33380	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS33385	COG2124	cytochrome p450
JN280_RS33390	COG2124	cytochrome p450
JN280_RS33405	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JN280_RS33440	COG5010	COG0457 FOG TPR repeat
JN280_RS33445	COG4789	Type iii secretion
JN280_RS33465	COG4792	protein secretion
JN280_RS33470	COG4791	protein targeting
JN280_RS33475	COG4794	Type iii secretion
JN280_RS33480	COG4790	Type iii secretion
JN280_RS33485	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JN280_RS33495	COG1157	protein secretion by the type III secretion system
JN280_RS33500	COG1317	bacterial-type flagellum organization
JN280_RS33510	COG4669	(LipO)protein
JN280_RS33530	COG5461	TIGRFAM pilus (Caulobacter type) biogenesis lipoprotein CpaD
JN280_RS33535	COG4964	Belongs to the GSP D family
JN280_RS33540	COG0745	RESPONSE REGULATOR receiver
JN280_RS33545	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JN280_RS33565	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JN280_RS33745	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JN280_RS33760	COG4959	Type IV secretory pathway protease TraF
JN280_RS33790	COG0583	DNA-binding transcription factor activity
JN280_RS33795	COG3153	acetyltransferase
JN280_RS33800	COG3594	Acyltransferase
JN280_RS33810	COG0583	DNA-binding transcription factor activity
JN280_RS33830	COG0726	polysaccharide deacetylase
JN280_RS33850	COG2192	nodulation
JN280_RS33860	COG1131	(ABC) transporter
JN280_RS33865	COG1215	transferase activity, transferring glycosyl groups
JN280_RS33870	COG3153	acetyltransferase
JN280_RS33890	COG1475	DNA binding
JN280_RS33935	COG3047	cAMP biosynthetic process
JN280_RS33950	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JN280_RS33965	COG4957	zinc ion binding
JN280_RS33970	COG1278	Cold shock
JN280_RS33975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JN280_RS33980	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JN280_RS33985	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JN280_RS34000	COG1476	TRANSCRIPTIONal
JN280_RS34035	COG2197	response regulator
JN280_RS34040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JN280_RS34045	COG1522	sequence-specific DNA binding
JN280_RS34060	COG0583	DNA-binding transcription factor activity
JN280_RS34065	COG2301	Belongs to the HpcH HpaI aldolase family
JN280_RS34075	COG3799	methylaspartate ammonia-lyase activity
JN280_RS34105	COG1181	Belongs to the D-alanine--D-alanine ligase family
JN280_RS34115	COG3608	succinylglutamate desuccinylase aspartoacylase
JN280_RS34120	COG1126	abc transporter atp-binding protein
JN280_RS34125	COG1126	abc transporter atp-binding protein
JN280_RS34130	COG0765	amino acid transport
JN280_RS34135	COG0765	amino acid transport
JN280_RS34140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN280_RS34165	COG1012	belongs to the aldehyde dehydrogenase family
JN280_RS34170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JN280_RS34185	COG4974	Belongs to the 'phage' integrase family
JN280_RS34190	COG0582	viral genome integration into host DNA
JN280_RS34195	COG4974	Belongs to the 'phage' integrase family
JN280_RS34210	COG0006	proline dipeptidase activity
JN280_RS34215	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JN280_RS34235	COG2801	Transposase and inactivated derivatives
JN280_RS34270	COG1522	sequence-specific DNA binding
JN280_RS34275	COG0583	DNA-binding transcription factor activity
JN280_RS34300	COG2801	Transposase and inactivated derivatives
JN280_RS34325	COG4608	Belongs to the ABC transporter superfamily
JN280_RS34335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN280_RS34350	COG2801	Transposase and inactivated derivatives
JN280_RS34365	COG1522	sequence-specific DNA binding
JN280_RS34380	COG2843	Capsule synthesis protein
JN280_RS34445	COG0006	proline dipeptidase activity
JN280_RS34475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN280_RS34500	COG2771	luxR family
JN280_RS34510	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JN280_RS34515	COG0316	Belongs to the HesB IscA family
JN280_RS34525	COG0602	queuosine metabolic process
JN280_RS34530	COG0720	synthase
JN280_RS34560	COG1609	Transcriptional regulator
JN280_RS34605	COG3383	formate dehydrogenase (NAD+) activity
JN280_RS34615	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JN280_RS34615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JN280_RS34640	COG4689	acetoacetate decarboxylase
JN280_RS34645	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JN280_RS34660	COG0745	RESPONSE REGULATOR receiver
JN280_RS34670	COG1433	Dinitrogenase iron-molybdenum cofactor
JN280_RS34675	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
JN280_RS34680	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
JN280_RS34685	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
JN280_RS34690	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
JN280_RS34695	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
JN280_RS34745	COG0210	DNA helicase
JN280_RS34750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN280_RS34760	COG4608	Belongs to the ABC transporter superfamily
JN280_RS34765	COG0444	Belongs to the ABC transporter superfamily
JN280_RS34775	COG1349	DNA-binding transcription factor activity
JN280_RS34780	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JN280_RS34790	COG0367	asparagine synthase
JN280_RS34805	COG1213	nucleotidyl transferase
JN280_RS34820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN280_RS34825	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS34830	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
JN280_RS34840	COG2124	cytochrome p450
JN280_RS34850	COG0678	peroxiredoxin activity
JN280_RS34855	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JN280_RS34865	COG3383	formate dehydrogenase (NAD+) activity
JN280_RS34870	COG5420	small protein containing a coiled-coil domain
JN280_RS34875	COG5265	(ABC) transporter
JN280_RS34880	COG1104	cysteine desulfurase activity
JN280_RS34890	COG2086	electron transfer activity
JN280_RS34895	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JN280_RS34900	COG0644	oxidoreductase
JN280_RS34915	COG0535	radical SAM domain protein
JN280_RS34920	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JN280_RS34925	COG5554	nitrogen fixation
JN280_RS34930	COG5554	nitrogen fixation
JN280_RS34945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JN280_RS34950	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
JN280_RS34965	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JN280_RS34980	COG2204	response regulator
JN280_RS34990	COG1301	dicarboxylic acid transport
JN280_RS35000	COG3604	Transcriptional regulator
JN280_RS35010	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JN280_RS35015	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JN280_RS35025	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JN280_RS35040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JN280_RS35045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JN280_RS35050	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JN280_RS35090	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JN280_RS35105	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JN280_RS35110	COG0459	protein refolding
JN280_RS35120	COG1012	belongs to the aldehyde dehydrogenase family
JN280_RS35150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JN280_RS35160	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JN280_RS35165	COG0720	synthase
JN280_RS35170	COG0602	queuosine metabolic process
JN280_RS35175	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JN280_RS35190	COG2022	thiamine diphosphate biosynthetic process
JN280_RS35205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN280_RS35210	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JN280_RS35230	COG1525	nuclease
JN280_RS35255	COG1414	Transcriptional regulator
JN280_RS35260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN280_RS35275	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
JN280_RS35285	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JN280_RS35290	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JN280_RS35320	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JN280_RS35330	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS35340	COG1960	acyl-CoA dehydrogenase activity
JN280_RS35345	COG1960	acyl-CoA dehydrogenase activity
JN280_RS35355	COG1024	Enoyl-CoA hydratase
JN280_RS35360	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS35380	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JN280_RS35380	COG1672	PFAM Archaeal ATPase
JN280_RS35390	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JN280_RS35395	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JN280_RS35400	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JN280_RS35405	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JN280_RS35420	COG3265	gluconokinase activity
JN280_RS35425	COG1028	Short-chain dehydrogenase reductase Sdr
JN280_RS35430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JN280_RS35440	COG1063	alcohol dehydrogenase
JN280_RS35445	COG1609	Transcriptional regulator
JN280_RS35460	COG0156	8-amino-7-oxononanoate synthase activity
JN280_RS35465	COG0436	Aminotransferase
JN280_RS35490	COG1970	mechanosensitive ion channel activity
JN280_RS35495	COG2205	protein histidine kinase activity
JN280_RS35495	COG0784	Response regulator, receiver
JN280_RS35515	COG0167	dihydroorotate dehydrogenase activity
JN280_RS35525	COG0123	including yeast histone deacetylase and acetoin utilization protein
JN280_RS35555	COG0717	Belongs to the dCTP deaminase family
JN280_RS35575	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JN280_RS35580	COG2967	ApaG domain
JN280_RS35590	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JN280_RS35595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JN280_RS35620	COG0704	Plays a role in the regulation of phosphate uptake
JN280_RS35625	COG5002	protein histidine kinase activity
JN280_RS35630	COG2326	polyphosphate kinase activity
JN280_RS35635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN280_RS35640	COG1309	transcriptional regulator
JN280_RS35645	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JN280_RS35650	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JN280_RS35660	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JN280_RS35665	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JN280_RS35685	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
JN280_RS35695	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JN280_RS35705	COG1024	Enoyl-CoA hydratase
JN280_RS35705	COG1250	3-hydroxyacyl-CoA dehydrogenase
JN280_RS35710	COG0183	Belongs to the thiolase family
JN280_RS35715	COG1960	acyl-CoA dehydrogenase activity
JN280_RS35720	COG1960	acyl-CoA dehydrogenase activity
JN280_RS35765	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JN280_RS35780	COG3260	NADH ubiquinone oxidoreductase 20
JN280_RS35785	COG0649	NAD binding
JN280_RS35790	COG0651	ATP synthesis coupled electron transport
JN280_RS35805	COG0651	ATP synthesis coupled electron transport
JN280_RS35815	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JN280_RS35820	COG3119	arylsulfatase activity
JN280_RS35830	COG0583	DNA-binding transcription factor activity
JN280_RS35835	COG0601	transmembrane transport
JN280_RS35845	COG4172	Belongs to the ABC transporter superfamily
JN280_RS35850	COG3119	arylsulfatase activity
JN280_RS35860	COG0625	glutathione transferase activity
JN280_RS35875	COG0789	Transcriptional regulator
JN280_RS35885	COG0730	response to heat
JN280_RS35895	COG0277	FAD linked oxidase domain protein
JN280_RS35905	COG1414	Transcriptional regulator
JN280_RS35915	COG1176	ABC-type spermidine putrescine transport system, permease component I
JN280_RS35935	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN280_RS35940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JN280_RS35945	COG0235	Class ii aldolase
JN280_RS35950	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JN280_RS35955	COG0028	Belongs to the TPP enzyme family
JN280_RS35980	COG1201	RNA secondary structure unwinding
JN280_RS35990	COG2226	methyltransferase
JN280_RS36000	COG1793	dna ligase
JN280_RS36035	COG0659	secondary active sulfate transmembrane transporter activity
JN280_RS36055	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JN280_RS36065	COG4608	Belongs to the ABC transporter superfamily
JN280_RS36070	COG0444	Belongs to the ABC transporter superfamily
JN280_RS36075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN280_RS36080	COG0601	transmembrane transport
JN280_RS36085	COG0747	negative chemotaxis
JN280_RS36095	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS36130	COG0166	Belongs to the GPI family
JN280_RS36135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JN280_RS36140	COG5598	trimethylamine methyltransferase
JN280_RS36150	COG0129	dihydroxy-acid dehydratase activity
JN280_RS36160	COG0489	protein tyrosine kinase activity
JN280_RS36180	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN280_RS36180	COG4797	methyltransferase
JN280_RS36240	COG3383	formate dehydrogenase (NAD+) activity
JN280_RS36245	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JN280_RS36260	COG2376	Dihydroxyacetone kinase
JN280_RS36270	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JN280_RS36275	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JN280_RS36285	COG1461	Dihydroxyacetone kinase
JN280_RS36290	COG1082	Xylose isomerase domain protein TIM barrel
JN280_RS36295	COG3842	ATPase activity
JN280_RS36310	COG0395	ABC-type sugar transport system, permease component
JN280_RS36315	COG1175	transmembrane transport
JN280_RS36320	COG1840	ABC-type Fe3 transport system, periplasmic component
JN280_RS36325	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JN280_RS36340	COG1177	transmembrane transport
JN280_RS36345	COG1176	ABC-type spermidine putrescine transport system, permease component I
JN280_RS36350	COG3842	ATPase activity
JN280_RS36355	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JN280_RS36360	COG0583	DNA-binding transcription factor activity
JN280_RS36390	COG0583	DNA-binding transcription factor activity
JN280_RS36405	COG0745	RESPONSE REGULATOR receiver
JN280_RS36425	COG4175	Glycine betaine
JN280_RS36425	COG0517	IMP dehydrogenase activity
JN280_RS36430	COG4176	ABC-type proline glycine betaine transport system permease component
JN280_RS36455	COG2340	Cysteine-rich secretory protein family
JN280_RS36470	COG0402	S-adenosylhomocysteine deaminase activity
JN280_RS36475	COG1079	Belongs to the binding-protein-dependent transport system permease family
JN280_RS36480	COG4603	Belongs to the binding-protein-dependent transport system permease family
JN280_RS36485	COG3845	ABC transporter
JN280_RS36520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JN280_RS36540	COG0395	ABC-type sugar transport system, permease component
JN280_RS36545	COG1175	transmembrane transport
JN280_RS36555	COG0583	DNA-binding transcription factor activity
JN280_RS36590	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JN280_RS36675	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
JN280_RS36685	COG1797	cobyrinic acid a,c-diamide synthase activity
JN280_RS36690	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JN280_RS36695	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JN280_RS36705	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JN280_RS36710	COG2205	protein histidine kinase activity
JN280_RS36765	COG4608	Belongs to the ABC transporter superfamily
JN280_RS36770	COG0444	Belongs to the ABC transporter superfamily
JN280_RS36775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN280_RS36780	COG0601	transmembrane transport
JN280_RS36785	COG0747	negative chemotaxis
JN280_RS36790	COG1396	sequence-specific DNA binding
JN280_RS36795	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JN280_RS36800	COG1473	amidohydrolase
JN280_RS36825	COG0402	S-adenosylhomocysteine deaminase activity
JN280_RS36830	COG3842	ATPase activity
JN280_RS36835	COG1177	transmembrane transport
JN280_RS36840	COG1176	ABC-type spermidine putrescine transport system, permease component I
JN280_RS36850	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS36875	COG1802	Transcriptional regulator
JN280_RS36905	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JN280_RS36925	COG1984	allophanate hydrolase subunit 2
JN280_RS36930	COG1879	ABC-type sugar transport system periplasmic component
JN280_RS36935	COG1129	ABC transporter
JN280_RS36940	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS36960	COG4172	Belongs to the ABC transporter superfamily
JN280_RS36970	COG0747	negative chemotaxis
JN280_RS36975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN280_RS36985	COG2188	Transcriptional regulator
JN280_RS37000	COG3409	Peptidoglycan-binding domain 1 protein
JN280_RS37000	COG3267	Type II secretory pathway component ExeA
JN280_RS37015	COG1216	Glycosyl transferase, family 2
JN280_RS37055	COG0463	Glycosyl transferase, family 2
JN280_RS37060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JN280_RS37070	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS37085	COG1215	transferase activity, transferring glycosyl groups
JN280_RS37095	COG0673	inositol 2-dehydrogenase activity
JN280_RS37110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JN280_RS37115	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JN280_RS37125	COG1088	dTDP-glucose 4,6-dehydratase activity
JN280_RS37135	COG1596	polysaccharide export
JN280_RS37140	COG2197	response regulator
JN280_RS37150	COG2197	response regulator
JN280_RS37165	COG2274	protein secretion by the type I secretion system
JN280_RS37175	COG0523	cobalamin synthesis protein
JN280_RS37230	COG1366	Belongs to the anti-sigma-factor antagonist family
JN280_RS37290	COG0668	transmembrane transport
JN280_RS37295	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
JN280_RS37315	COG0500	methyltransferase
JN280_RS37340	COG2226	methyltransferase
JN280_RS37350	COG2208	phosphoserine phosphatase activity
JN280_RS37375	COG0628	permease
JN280_RS37425	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JN280_RS37440	COG4213	ABC transporter substrate-binding protein
JN280_RS37445	COG2273	Hydrolase Family 16
JN280_RS37445	COG5297	Belongs to the glycosyl hydrolase family 6
JN280_RS37460	COG1596	polysaccharide export
JN280_RS37465	COG0489	protein tyrosine kinase activity
JN280_RS37510	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS37530	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JN280_RS37535	COG0477	Major facilitator Superfamily
JN280_RS37545	COG1082	Xylose isomerase domain protein TIM barrel
JN280_RS37550	COG1309	transcriptional regulator
JN280_RS37595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JN280_RS37610	COG3842	ATPase activity
JN280_RS37630	COG1175	transmembrane transport
JN280_RS37645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JN280_RS37655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN280_RS37660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN280_RS37665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JN280_RS37665	COG1116	anion transmembrane transporter activity
JN280_RS37670	COG0673	inositol 2-dehydrogenase activity
JN280_RS37680	COG0837	glucose binding
JN280_RS37685	COG0318	PFAM AMP-dependent synthetase and ligase
JN280_RS37725	COG0583	DNA-binding transcription factor activity
JN280_RS37735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JN280_RS37735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JN280_RS37765	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JN280_RS37805	COG1126	abc transporter atp-binding protein
JN280_RS37810	COG0765	amino acid transport
JN280_RS37815	COG0765	amino acid transport
JN280_RS37820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN280_RS37830	COG4948	Mandelate Racemase Muconate Lactonizing
JN280_RS37835	COG1733	regulation of RNA biosynthetic process
JN280_RS37880	COG1902	pentaerythritol trinitrate reductase activity
JN280_RS37890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN280_RS37895	COG1960	acyl-CoA dehydrogenase activity
JN280_RS37905	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JN280_RS37915	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JN280_RS37930	COG1802	Transcriptional regulator
JN280_RS37940	COG0411	ABC transporter
JN280_RS37960	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JN280_RS37970	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JN280_RS37985	COG1063	alcohol dehydrogenase
JN280_RS37995	COG0179	Fumarylacetoacetate (FAA) hydrolase
JN280_RS38010	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JN280_RS38015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN280_RS38040	COG2159	amidohydrolase
JN280_RS38045	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JN280_RS38050	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JN280_RS38060	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JN280_RS38065	COG0512	Glutamine amidotransferase of anthranilate synthase
JN280_RS38065	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JN280_RS38100	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JN280_RS38125	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JN280_RS38140	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JN280_RS38140	COG0446	pyridine nucleotide-disulphide oxidoreductase
JN280_RS38170	COG2301	Belongs to the HpcH HpaI aldolase family
JN280_RS38175	COG0045	succinate-CoA ligase (ADP-forming) activity
JN280_RS38180	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JN280_RS38185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JN280_RS38190	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JN280_RS38210	COG4214	carbohydrate transport
JN280_RS38230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JN280_RS38250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JN280_RS38255	COG0517	IMP dehydrogenase activity
JN280_RS38255	COG4175	Glycine betaine
JN280_RS38350	COG3620	sequence-specific DNA binding
JN280_RS38355	COG3550	peptidyl-serine autophosphorylation
JN280_RS38370	COG3609	addiction module antidote protein, CC2985 family
JN280_RS38405	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JN280_RS38410	COG0594	ribonuclease P activity
JN280_RS38415	COG0706	membrane insertase activity
JN280_RS38425	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JN280_RS38430	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JN280_RS38435	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
JN280_RS38445	COG1595	DNA-templated transcription, initiation
JN280_RS38450	COG1653	transport
JN280_RS38470	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JN280_RS38490	COG3706	GGDEF domain
JN280_RS38510	COG2171	N-acyltransferase activity
JN280_RS38520	COG1129	ABC transporter
JN280_RS38525	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN280_RS38540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JN280_RS38550	COG0101	tRNA pseudouridine synthase activity
JN280_RS38555	COG3153	acetyltransferase
JN280_RS38560	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JN280_RS38585	COG0242	peptide deformylase activity
JN280_RS38595	COG2076	Multidrug Resistance protein
JN280_RS38610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN280_RS38620	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JN280_RS38630	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JN280_RS38635	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JN280_RS38650	COG2816	NAD+ diphosphatase activity
JN280_RS38655	COG0077	Prephenate dehydratase
JN280_RS38655	COG1605	Chorismate mutase
JN280_RS38660	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
JN280_RS38665	COG3474	cytochrome
JN280_RS38670	COG4166	transmembrane transport
JN280_RS38675	COG4166	transmembrane transport
JN280_RS38680	COG4174	ABC transporter (Permease)
JN280_RS38685	COG4239	(ABC) transporter, permease
JN280_RS38700	COG4172	Belongs to the ABC transporter superfamily
JN280_RS38715	COG1335	isochorismatase
JN280_RS38720	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JN280_RS38730	COG4608	Belongs to the ABC transporter superfamily
JN280_RS38745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN280_RS38760	COG2515	1-aminocyclopropane-1-carboxylate deaminase
JN280_RS38770	COG0756	dUTP diphosphatase activity
JN280_RS38775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JN280_RS38780	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JN280_RS38805	COG2358	TRAP transporter, solute receptor (TAXI family
JN280_RS38850	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JN280_RS38860	COG0842	Transport permease protein
JN280_RS38865	COG1131	(ABC) transporter
JN280_RS38880	COG2954	triphosphatase activity
JN280_RS38900	COG1595	DNA-templated transcription, initiation
JN280_RS38920	COG0747	negative chemotaxis
JN280_RS38925	COG0601	transmembrane transport
JN280_RS38930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN280_RS38935	COG0444	Belongs to the ABC transporter superfamily
JN280_RS38985	COG3220	belongs to the UPF0276 family
JN280_RS39020	COG0583	DNA-binding transcription factor activity
JN280_RS39035	COG0481	GTPase activity
JN280_RS39040	COG0791	NLP P60 protein
JN280_RS39050	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JN280_RS39085	COG4964	Belongs to the GSP D family
JN280_RS39120	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JN280_RS39125	COG1024	Enoyl-CoA hydratase
JN280_RS39140	COG0268	Binds directly to 16S ribosomal RNA