locus-tag	class	description
EB232_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EB232_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EB232_RS00030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EB232_RS00050	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EB232_RS00060	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EB232_RS00065	COG3300	MHYT domain
EB232_RS00065	COG5001	Diguanylate cyclase
EB232_RS00070	COG2813	Specifically methylates the guanine in position
EB232_RS00075	COG1185	polyribonucleotide nucleotidyltransferase activity
EB232_RS00080	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EB232_RS00085	COG0598	Magnesium transport protein CorA
EB232_RS00090	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EB232_RS00095	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EB232_RS00100	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EB232_RS00115	COG0779	Required for maturation of 30S ribosomal subunits
EB232_RS00125	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EB232_RS00130	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EB232_RS00135	COG1396	sequence-specific DNA binding
EB232_RS00140	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EB232_RS00155	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EB232_RS00160	COG1702	phosphate starvation-inducible protein PhoH
EB232_RS00165	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EB232_RS00180	COG1214	PFAM Peptidase M22, glycoprotease
EB232_RS00225	COG3609	addiction module antidote protein, CC2985 family
EB232_RS00230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EB232_RS00250	COG4608	Belongs to the ABC transporter superfamily
EB232_RS00255	COG0444	Belongs to the ABC transporter superfamily
EB232_RS00265	COG0601	transmembrane transport
EB232_RS00275	COG2951	lytic endotransglycosylase activity
EB232_RS00280	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EB232_RS00295	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EB232_RS00300	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EB232_RS00315	COG2816	NAD+ diphosphatase activity
EB232_RS00330	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EB232_RS00335	COG3474	cytochrome
EB232_RS00340	COG4166	transmembrane transport
EB232_RS00345	COG4166	transmembrane transport
EB232_RS00350	COG4174	ABC transporter (Permease)
EB232_RS00355	COG4239	(ABC) transporter, permease
EB232_RS00360	COG4172	Belongs to the ABC transporter superfamily
EB232_RS00390	COG1793	dna ligase
EB232_RS00415	COG1295	ribonuclease BN
EB232_RS00430	COG1595	DNA-templated transcription, initiation
EB232_RS00485	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EB232_RS00500	COG0601	transmembrane transport
EB232_RS00505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB232_RS00510	COG0444	Belongs to the ABC transporter superfamily
EB232_RS00540	COG1024	Enoyl-CoA hydratase
EB232_RS00545	COG1960	acyl-CoA dehydrogenase activity
EB232_RS00555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB232_RS00560	COG3836	Belongs to the HpcH HpaI aldolase family
EB232_RS00565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB232_RS00575	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EB232_RS00585	COG4608	Belongs to the ABC transporter superfamily
EB232_RS00590	COG0444	Belongs to the ABC transporter superfamily
EB232_RS00595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB232_RS00600	COG0601	transmembrane transport
EB232_RS00605	COG0747	negative chemotaxis
EB232_RS00610	COG0318	PFAM AMP-dependent synthetase and ligase
EB232_RS00615	COG2264	protein methyltransferase activity
EB232_RS00625	COG0166	Belongs to the GPI family
EB232_RS00630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB232_RS00655	COG0129	dihydroxy-acid dehydratase activity
EB232_RS00665	COG0489	protein tyrosine kinase activity
EB232_RS00670	COG3706	GGDEF domain
EB232_RS00675	COG0583	DNA-binding transcription factor activity
EB232_RS00690	COG3383	formate dehydrogenase (NAD+) activity
EB232_RS00695	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EB232_RS00705	COG2197	response regulator
EB232_RS00730	COG1177	transmembrane transport
EB232_RS00735	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB232_RS00740	COG3842	ATPase activity
EB232_RS00745	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EB232_RS00760	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EB232_RS00775	COG1349	DNA-binding transcription factor activity
EB232_RS00790	COG2226	methyltransferase
EB232_RS00800	COG0697	spore germination
EB232_RS00805	COG0402	S-adenosylhomocysteine deaminase activity
EB232_RS00810	COG1132	(ABC) transporter
EB232_RS00815	COG0129	dihydroxy-acid dehydratase activity
EB232_RS00825	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EB232_RS00830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB232_RS00835	COG0154	amidase activity
EB232_RS00840	COG0121	glutamine amidotransferase
EB232_RS00850	COG1522	sequence-specific DNA binding
EB232_RS00855	COG0756	dUTP diphosphatase activity
EB232_RS00860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EB232_RS00885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB232_RS00895	COG3706	GGDEF domain
EB232_RS00900	COG0280	phosphate acetyltransferase
EB232_RS00900	COG0281	malic enzyme
EB232_RS00910	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EB232_RS00915	COG0656	L-ascorbic acid biosynthetic process
EB232_RS00940	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EB232_RS00945	COG0728	peptidoglycan biosynthetic process
EB232_RS00950	COG0180	Tryptophanyl-tRNA synthetase
EB232_RS00960	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EB232_RS00965	COG1388	LysM domain
EB232_RS00965	COG1376	ErfK ybiS ycfS ynhG family protein
EB232_RS00980	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EB232_RS00985	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EB232_RS00995	COG1643	Atp-dependent helicase
EB232_RS01015	COG1175	transmembrane transport
EB232_RS01045	COG1461	Dihydroxyacetone kinase
EB232_RS01070	COG2376	Dihydroxyacetone kinase
EB232_RS01110	COG0489	protein tyrosine kinase activity
EB232_RS01110	COG3206	protein involved in exopolysaccharide biosynthesis
EB232_RS01115	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EB232_RS01120	COG1215	transferase activity, transferring glycosyl groups
EB232_RS01125	COG1215	transferase activity, transferring glycosyl groups
EB232_RS01130	COG1215	transferase activity, transferring glycosyl groups
EB232_RS01135	COG0438	transferase activity, transferring glycosyl groups
EB232_RS01150	COG0463	Glycosyl transferase, family 2
EB232_RS01165	COG2273	Hydrolase Family 16
EB232_RS01175	COG1215	transferase activity, transferring glycosyl groups
EB232_RS01210	COG1132	(ABC) transporter
EB232_RS01220	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EB232_RS01225	COG1596	polysaccharide export
EB232_RS01235	COG3307	-O-antigen
EB232_RS01240	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS01245	COG4647	ligase activity
EB232_RS01250	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
EB232_RS01255	COG0145	ligase activity
EB232_RS01265	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS01275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EB232_RS01280	COG0438	transferase activity, transferring glycosyl groups
EB232_RS01295	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS01310	COG0431	NADPH-dependent FMN reductase
EB232_RS01320	COG0410	ABC transporter
EB232_RS01340	COG0411	ABC transporter
EB232_RS01345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB232_RS01355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB232_RS01375	COG1335	isochorismatase
EB232_RS01385	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS01400	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS01415	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EB232_RS01425	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EB232_RS01430	COG0539	negative regulation of cytoplasmic translation
EB232_RS01445	COG2235	arginine
EB232_RS01460	COG4215	(ABC) transporter
EB232_RS01470	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EB232_RS01560	COG5001	Diguanylate cyclase
EB232_RS01590	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EB232_RS01595	COG1063	alcohol dehydrogenase
EB232_RS01600	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EB232_RS01605	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EB232_RS01615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EB232_RS01620	COG1609	Transcriptional regulator
EB232_RS01650	COG0523	cobalamin synthesis protein
EB232_RS01675	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EB232_RS01690	COG1573	uracil-dna glycosylase
EB232_RS01700	COG4702	Belongs to the UPF0303 family
EB232_RS01705	COG0402	S-adenosylhomocysteine deaminase activity
EB232_RS01715	COG0583	DNA-binding transcription factor activity
EB232_RS01720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB232_RS01730	COG0384	phenazine biosynthesis protein PhzF
EB232_RS01740	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EB232_RS01750	COG2351	hydroxyisourate hydrolase activity
EB232_RS01755	COG3195	allantoin biosynthetic process
EB232_RS01755	COG3648	Uricase
EB232_RS01760	COG3257	ureidoglycine aminohydrolase activity
EB232_RS01765	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
EB232_RS01790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB232_RS01805	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EB232_RS01810	COG1595	DNA-templated transcription, initiation
EB232_RS01830	COG1609	Transcriptional regulator
EB232_RS01835	COG1653	transport
EB232_RS01840	COG1175	transmembrane transport
EB232_RS01845	COG0395	ABC-type sugar transport system, permease component
EB232_RS01850	COG0366	Alpha amylase catalytic
EB232_RS01855	COG3842	ATPase activity
EB232_RS01870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EB232_RS01885	COG1215	transferase activity, transferring glycosyl groups
EB232_RS01890	COG0463	Glycosyl transferase, family 2
EB232_RS01930	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EB232_RS01935	COG0745	RESPONSE REGULATOR receiver
EB232_RS01940	COG2205	protein histidine kinase activity
EB232_RS01945	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EB232_RS01950	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EB232_RS01950	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EB232_RS01960	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EB232_RS01965	COG2205	protein histidine kinase activity
EB232_RS01970	COG3178	'Phosphotransferase
EB232_RS01975	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EB232_RS01980	COG2887	Belongs to the helicase family. UvrD subfamily
EB232_RS01985	COG1074	ATP-dependent DNA helicase activity
EB232_RS02025	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EB232_RS02030	COG0159	tryptophan synthase activity
EB232_RS02035	COG0133	tryptophan synthase activity
EB232_RS02040	COG0135	phosphoribosylanthranilate isomerase activity
EB232_RS02060	COG3135	benzoate transporter
EB232_RS02070	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EB232_RS02080	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EB232_RS02085	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EB232_RS02090	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EB232_RS02100	COG0072	phenylalanine-tRNA ligase activity
EB232_RS02100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EB232_RS02115	COG0667	Aldo Keto reductase
EB232_RS02150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EB232_RS02180	COG1250	3-hydroxyacyl-CoA dehydrogenase
EB232_RS02190	COG3246	L-lysine catabolic process to acetate
EB232_RS02195	COG4977	sequence-specific DNA binding
EB232_RS02205	COG2115	Belongs to the xylose isomerase family
EB232_RS02215	COG1070	Carbohydrate kinase
EB232_RS02225	COG3468	outer membrane autotransporter barrel domain protein
EB232_RS02230	COG1280	lysine exporter protein (LysE YggA)
EB232_RS02235	COG1388	LysM domain
EB232_RS02235	COG1376	ErfK ybiS ycfS ynhG family protein
EB232_RS02240	COG0205	6-phosphofructokinase activity
EB232_RS02245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EB232_RS02255	COG1072	(Pantothenic acid kinase))
EB232_RS02260	COG0140	phosphoribosyl-ATP diphosphatase activity
EB232_RS02265	COG0107	imidazoleglycerol-phosphate synthase activity
EB232_RS02275	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EB232_RS02285	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EB232_RS02295	COG0131	Imidazoleglycerol-phosphate dehydratase
EB232_RS02300	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EB232_RS02315	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EB232_RS02340	COG1609	Transcriptional regulator
EB232_RS02355	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS02365	COG0673	inositol 2-dehydrogenase activity
EB232_RS02370	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS02375	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EB232_RS02400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB232_RS02405	COG3962	Belongs to the TPP enzyme family
EB232_RS02410	COG1082	Xylose isomerase domain protein TIM barrel
EB232_RS02420	COG3718	enzyme involved in inositol metabolism
EB232_RS02425	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EB232_RS02430	COG3454	Phosphonate metabolism
EB232_RS02435	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EB232_RS02450	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS02470	COG2824	Alkylphosphonate utilization operon protein PhnA
EB232_RS02485	COG1686	Belongs to the peptidase S11 family
EB232_RS02495	COG1072	(Pantothenic acid kinase))
EB232_RS02505	COG0625	glutathione transferase activity
EB232_RS02520	COG0829	nickel cation binding
EB232_RS02525	COG0831	urea catabolic process
EB232_RS02530	COG3813	Protein conserved in bacteria
EB232_RS02540	COG0832	Belongs to the urease beta subunit family
EB232_RS02550	COG0804	urea catabolic process
EB232_RS02565	COG0625	glutathione transferase activity
EB232_RS02570	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
EB232_RS02575	COG0830	nickel cation binding
EB232_RS02585	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EB232_RS02595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EB232_RS02610	COG0583	DNA-binding transcription factor activity
EB232_RS02650	COG3842	ATPase activity
EB232_RS02655	COG1063	alcohol dehydrogenase
EB232_RS02660	COG0395	ABC-type sugar transport system, permease component
EB232_RS02680	COG0534	Mate efflux family protein
EB232_RS02715	COG0765	amino acid transport
EB232_RS02720	COG0765	amino acid transport
EB232_RS02725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB232_RS02735	COG0583	DNA-binding transcription factor activity
EB232_RS02740	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EB232_RS02780	COG1335	isochorismatase
EB232_RS02785	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EB232_RS02810	COG1846	Transcriptional regulator
EB232_RS02815	COG0483	inositol monophosphate 1-phosphatase activity
EB232_RS02820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB232_RS02825	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EB232_RS02830	COG0628	permease
EB232_RS02845	COG2076	Multidrug Resistance protein
EB232_RS02875	COG0242	peptide deformylase activity
EB232_RS02880	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EB232_RS02890	COG0101	tRNA pseudouridine synthase activity
EB232_RS02900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB232_RS02905	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EB232_RS02925	COG2171	N-acyltransferase activity
EB232_RS02940	COG3706	GGDEF domain
EB232_RS02975	COG3186	Phenylalanine-4-hydroxylase
EB232_RS02980	COG1522	sequence-specific DNA binding
EB232_RS02985	COG1032	radical SAM domain protein
EB232_RS02990	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EB232_RS03015	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EB232_RS03020	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EB232_RS03040	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EB232_RS03055	COG1566	PFAM secretion protein HlyD family protein
EB232_RS03065	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EB232_RS03070	COG0706	membrane insertase activity
EB232_RS03075	COG0594	ribonuclease P activity
EB232_RS03080	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EB232_RS03085	COG4191	Histidine kinase
EB232_RS03135	COG0405	Gamma-glutamyltransferase
EB232_RS03140	COG0318	PFAM AMP-dependent synthetase and ligase
EB232_RS03145	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EB232_RS03185	COG0747	negative chemotaxis
EB232_RS03210	COG1846	Transcriptional regulator
EB232_RS03220	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EB232_RS03225	COG2011	ABC-type metal ion transport system permease component
EB232_RS03230	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB232_RS03235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB232_RS03245	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
EB232_RS03260	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EB232_RS03265	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS03270	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS03275	COG0179	Fumarylacetoacetate (FAA) hydrolase
EB232_RS03285	COG0673	inositol 2-dehydrogenase activity
EB232_RS03290	COG0395	ABC-type sugar transport system, permease component
EB232_RS03295	COG1175	transmembrane transport
EB232_RS03305	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EB232_RS03310	COG2971	BadF BadG BcrA BcrD
EB232_RS03315	COG2188	Transcriptional regulator
EB232_RS03320	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EB232_RS03325	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EB232_RS03330	COG0579	oxidoreductase
EB232_RS03335	COG4178	(ABC) transporter
EB232_RS03345	COG0318	PFAM AMP-dependent synthetase and ligase
EB232_RS03370	COG0443	Heat shock 70 kDa protein
EB232_RS03375	COG0484	heat shock protein binding
EB232_RS03380	COG3963	phosphatidate phosphatase activity
EB232_RS03390	COG0284	orotidine-5'-phosphate decarboxylase activity
EB232_RS03400	COG1802	Transcriptional regulator
EB232_RS03415	COG3386	PFAM SMP-30 Gluconolaconase
EB232_RS03420	COG0800	Aldolase
EB232_RS03425	COG3734	2-keto-3-deoxy-galactonokinase
EB232_RS03430	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS03435	COG5001	Diguanylate cyclase
EB232_RS03455	COG0189	ligase activity
EB232_RS03515	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EB232_RS03610	COG3038	cytochrome b561
EB232_RS03620	COG0588	phosphoglycerate mutase activity
EB232_RS03625	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EB232_RS03630	COG1132	(ABC) transporter
EB232_RS03635	COG0837	glucose binding
EB232_RS03640	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
EB232_RS03650	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EB232_RS03660	COG1968	undecaprenyl-diphosphatase activity
EB232_RS03665	COG0792	nuclease activity
EB232_RS03670	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EB232_RS03685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EB232_RS03690	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EB232_RS03700	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EB232_RS03705	COG1420	regulation of RNA biosynthetic process
EB232_RS03720	COG1280	lysine exporter protein (LysE YggA)
EB232_RS03735	COG4941	Belongs to the sigma-70 factor family
EB232_RS03740	COG3795	YCII-related domain
EB232_RS03755	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EB232_RS03795	COG0842	Transport permease protein
EB232_RS03800	COG1131	(ABC) transporter
EB232_RS03815	COG2954	triphosphatase activity
EB232_RS03830	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EB232_RS03850	COG2094	Belongs to the DNA glycosylase MPG family
EB232_RS03855	COG0659	secondary active sulfate transmembrane transporter activity
EB232_RS03865	COG0671	phosphoesterase, PA-phosphatase related
EB232_RS03880	COG2197	response regulator
EB232_RS03895	COG3634	alkyl hydroperoxide reductase activity
EB232_RS03905	COG0842	Transport permease protein
EB232_RS03910	COG1131	(ABC) transporter
EB232_RS03915	COG1271	oxidase subunit
EB232_RS03920	COG1294	oxidase, subunit
EB232_RS03945	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EB232_RS03970	COG0481	GTPase activity
EB232_RS03980	COG0747	negative chemotaxis
EB232_RS03985	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EB232_RS03990	COG3030	protein affecting phage T7 exclusion by the F plasmid
EB232_RS04025	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EB232_RS04045	COG0626	cystathionine gamma-synthase activity
EB232_RS04060	COG0006	proline dipeptidase activity
EB232_RS04065	COG1335	isochorismatase
EB232_RS04080	COG0237	dephospho-CoA kinase activity
EB232_RS04085	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EB232_RS04090	COG0424	maF-like protein
EB232_RS04095	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EB232_RS04100	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EB232_RS04110	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EB232_RS04115	COG1331	Highly conserved protein containing a thioredoxin domain
EB232_RS04120	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EB232_RS04125	COG0445	tRNA wobble uridine modification
EB232_RS04130	COG0357	Ribosomal RNA small subunit methyltransferase G
EB232_RS04185	COG0463	Glycosyl transferase, family 2
EB232_RS04190	COG0671	phosphoesterase, PA-phosphatase related
EB232_RS04235	COG0251	oxidation-reduction process
EB232_RS04245	COG0110	maltose O-acetyltransferase activity
EB232_RS04250	COG2072	flavoprotein involved in K transport
EB232_RS04305	COG3118	belongs to the thioredoxin family
EB232_RS04310	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EB232_RS04315	COG2835	tetraacyldisaccharide 4'-kinase activity
EB232_RS04320	COG0587	DNA-directed DNA polymerase activity
EB232_RS04330	COG1280	lysine exporter protein (LysE YggA)
EB232_RS04345	COG2301	Belongs to the HpcH HpaI aldolase family
EB232_RS04360	COG0745	RESPONSE REGULATOR receiver
EB232_RS04365	COG2205	protein histidine kinase activity
EB232_RS04375	COG1801	Protein of unknown function DUF72
EB232_RS04390	COG0640	Transcriptional regulator
EB232_RS04400	COG0066	3-isopropylmalate dehydratase activity
EB232_RS04410	COG0251	oxidation-reduction process
EB232_RS04420	COG0473	3-isopropylmalate dehydrogenase activity
EB232_RS04450	COG0513	Belongs to the DEAD box helicase family
EB232_RS04455	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EB232_RS04470	COG3781	membrane
EB232_RS04495	COG0228	four-way junction DNA binding
EB232_RS04500	COG0287	Prephenate dehydrogenase
EB232_RS04500	COG1605	Chorismate mutase
EB232_RS04505	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EB232_RS04510	COG1266	CAAX protease self-immunity
EB232_RS04535	COG0137	argininosuccinate synthase activity
EB232_RS04540	COG5001	Diguanylate cyclase
EB232_RS04540	COG3300	MHYT domain
EB232_RS04560	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EB232_RS04580	COG3339	Conserved Protein
EB232_RS04585	COG2154	pterin-4-alpha-carbinolamine dehydratase
EB232_RS04590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EB232_RS04595	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EB232_RS04605	COG1136	(ABC) transporter
EB232_RS04610	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EB232_RS04615	COG0670	Belongs to the BI1 family
EB232_RS04640	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EB232_RS04645	COG4133	protoheme IX ABC transporter activity
EB232_RS04650	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EB232_RS04660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EB232_RS04680	COG0431	NADPH-dependent FMN reductase
EB232_RS04690	COG2917	probably involved in intracellular septation
EB232_RS04695	COG0552	protein localization to endoplasmic reticulum
EB232_RS04700	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EB232_RS04705	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EB232_RS04730	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EB232_RS04735	COG0039	L-malate dehydrogenase activity
EB232_RS04740	COG0045	succinate-CoA ligase (ADP-forming) activity
EB232_RS04755	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EB232_RS04760	COG0567	Dehydrogenase, E1 component
EB232_RS04765	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB232_RS04780	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS04805	COG4974	Belongs to the 'phage' integrase family
EB232_RS04810	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EB232_RS04815	COG0336	Belongs to the RNA methyltransferase TrmD family
EB232_RS04825	COG0335	large ribosomal subunit rRNA binding
EB232_RS04830	COG1764	response to oxidative stress
EB232_RS04835	COG1846	Transcriptional regulator
EB232_RS04845	COG0765	amino acid transport
EB232_RS04855	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EB232_RS04865	COG3706	GGDEF domain
EB232_RS04910	COG3132	Protein of unknown function, DUF480
EB232_RS04915	COG1764	response to oxidative stress
EB232_RS04925	COG3795	YCII-related domain
EB232_RS04940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EB232_RS04945	COG1946	Acyl-CoA thioesterase
EB232_RS04950	COG0347	Belongs to the P(II) protein family
EB232_RS04955	COG0004	ammonium transporteR
EB232_RS04960	COG2261	transglycosylase associated protein
EB232_RS04960	COG1674	ftsk spoiiie
EB232_RS04965	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EB232_RS04985	COG0745	RESPONSE REGULATOR receiver
EB232_RS05000	COG0583	DNA-binding transcription factor activity
EB232_RS05015	COG2264	protein methyltransferase activity
EB232_RS05030	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EB232_RS05035	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EB232_RS05040	COG0181	hydroxymethylbilane synthase activity
EB232_RS05065	COG0519	Catalyzes the synthesis of GMP from XMP
EB232_RS05065	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EB232_RS05085	COG4957	zinc ion binding
EB232_RS05100	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EB232_RS05110	COG1879	ABC-type sugar transport system periplasmic component
EB232_RS05115	COG1129	ABC transporter
EB232_RS05125	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS05130	COG1250	3-hydroxyacyl-CoA dehydrogenase
EB232_RS05130	COG1024	Enoyl-CoA hydratase
EB232_RS05145	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS05170	COG3842	ATPase activity
EB232_RS05175	COG1177	transmembrane transport
EB232_RS05195	COG1819	glycosyl
EB232_RS05205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB232_RS05210	COG1414	Transcriptional regulator
EB232_RS05215	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EB232_RS05220	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EB232_RS05225	COG0183	Belongs to the thiolase family
EB232_RS05265	COG1335	isochorismatase
EB232_RS05280	COG0848	biopolymer transport protein
EB232_RS05285	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EB232_RS05325	COG1872	DUF167
EB232_RS05330	COG1737	Transcriptional regulator
EB232_RS05355	COG0395	ABC-type sugar transport system, permease component
EB232_RS05390	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EB232_RS05400	COG1704	LemA family
EB232_RS05405	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EB232_RS05420	COG1247	-acetyltransferase
EB232_RS05425	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EB232_RS05435	COG1309	transcriptional regulator
EB232_RS05440	COG2271	Major facilitator Superfamily
EB232_RS05465	COG3511	phospholipase C
EB232_RS05490	COG2270	Major facilitator Superfamily
EB232_RS05495	COG0138	bifunctional purine biosynthesis protein purh
EB232_RS05505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EB232_RS05505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EB232_RS05510	COG0501	Belongs to the peptidase M48B family
EB232_RS05520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EB232_RS05535	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EB232_RS05550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EB232_RS05555	COG5425	PFAM Usg family protein
EB232_RS05565	COG0667	Aldo Keto reductase
EB232_RS05570	COG2814	Major facilitator Superfamily
EB232_RS05575	COG0583	DNA-binding transcription factor activity
EB232_RS05580	COG0667	Aldo Keto reductase
EB232_RS05590	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EB232_RS05595	COG0495	leucyl-tRNA aminoacylation
EB232_RS05610	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EB232_RS05620	COG1794	racemase activity, acting on amino acids and derivatives
EB232_RS05630	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EB232_RS05635	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EB232_RS05640	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EB232_RS05645	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EB232_RS05650	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EB232_RS05655	COG0681	Belongs to the peptidase S26 family
EB232_RS05660	COG0246	Mannitol dehydrogenase
EB232_RS05665	COG1904	glucuronate isomerase
EB232_RS05680	COG0514	ATP-dependent DNA helicase (RecQ)
EB232_RS05715	COG0583	DNA-binding transcription factor activity
EB232_RS05735	COG3743	rRNA binding
EB232_RS05735	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EB232_RS05740	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EB232_RS05745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EB232_RS05750	COG0456	acetyltransferase
EB232_RS05760	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EB232_RS05765	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EB232_RS05770	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EB232_RS05775	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EB232_RS05785	COG0799	negative regulation of ribosome biogenesis
EB232_RS05790	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EB232_RS05800	COG0793	Belongs to the peptidase S41A family
EB232_RS05810	COG0494	nUDIX hydrolase
EB232_RS05815	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EB232_RS05820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB232_RS05825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EB232_RS05850	COG3744	PilT protein domain protein
EB232_RS05860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EB232_RS05865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB232_RS05900	COG0683	leucine binding
EB232_RS05905	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EB232_RS05910	COG3750	Belongs to the UPF0335 family
EB232_RS05925	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EB232_RS05930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EB232_RS05965	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EB232_RS05975	COG1692	metallophosphoesterase
EB232_RS05980	COG0861	Integral membrane protein TerC family
EB232_RS05985	COG0217	transcriptional regulatory protein
EB232_RS06005	COG0702	epimerase
EB232_RS06025	COG0254	rRNA binding
EB232_RS06030	COG1132	(ABC) transporter
EB232_RS06055	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EB232_RS06080	COG1272	protein, Hemolysin III
EB232_RS06085	COG0483	inositol monophosphate 1-phosphatase activity
EB232_RS06090	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EB232_RS06110	COG1522	sequence-specific DNA binding
EB232_RS06115	COG2226	methyltransferase
EB232_RS06140	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EB232_RS06155	COG0632	four-way junction helicase activity
EB232_RS06160	COG2255	four-way junction helicase activity
EB232_RS06165	COG1408	metallophosphoesterase
EB232_RS06175	COG0824	Thioesterase
EB232_RS06195	COG0848	biopolymer transport protein
EB232_RS06205	COG0823	Involved in the tonB-independent uptake of proteins
EB232_RS06215	COG2885	chlorophyll binding
EB232_RS06225	COG0037	tRNA processing
EB232_RS06230	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EB232_RS06245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EB232_RS06260	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EB232_RS06265	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EB232_RS06270	COG0697	spore germination
EB232_RS06275	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EB232_RS06315	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EB232_RS06330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB232_RS06335	COG0765	amino acid transport
EB232_RS06340	COG1126	abc transporter atp-binding protein
EB232_RS06345	COG1329	Transcriptional regulator
EB232_RS06350	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EB232_RS06365	COG1309	transcriptional regulator
EB232_RS06375	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS06380	COG0183	Belongs to the thiolase family
EB232_RS06390	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
EB232_RS06410	COG0372	Belongs to the citrate synthase family
EB232_RS06415	COG0372	Belongs to the citrate synthase family
EB232_RS06445	COG0583	DNA-binding transcription factor activity
EB232_RS06450	COG2223	nitrite transmembrane transporter activity
EB232_RS06470	COG0469	pyruvate kinase activity
EB232_RS06485	COG0457	Tetratricopeptide repeat
EB232_RS06490	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EB232_RS06495	COG3755	Protein conserved in bacteria
EB232_RS06500	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EB232_RS06510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB232_RS06515	COG1737	Transcriptional regulator
EB232_RS06540	COG1921	L-seryl-tRNASec selenium transferase activity
EB232_RS06555	COG0765	amino acid transport
EB232_RS06560	COG0765	amino acid transport
EB232_RS06585	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EB232_RS06590	COG1196	nuclear chromosome segregation
EB232_RS06590	COG0741	lytic transglycosylase activity
EB232_RS06590	COG0739	heme binding
EB232_RS06610	COG2226	methyltransferase
EB232_RS06615	COG0784	Response regulator, receiver
EB232_RS06615	COG2205	protein histidine kinase activity
EB232_RS06615	COG5002	protein histidine kinase activity
EB232_RS06625	COG2084	Dehydrogenase
EB232_RS06630	COG3265	gluconokinase activity
EB232_RS06635	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS06645	COG1063	alcohol dehydrogenase
EB232_RS06650	COG1609	Transcriptional regulator
EB232_RS06665	COG1129	ABC transporter
EB232_RS06675	COG0142	geranyltranstransferase activity
EB232_RS06680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EB232_RS06685	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EB232_RS06735	COG0640	Transcriptional regulator
EB232_RS06790	COG0346	lactoylglutathione lyase activity
EB232_RS06810	COG3588	fructose-bisphosphate aldolase
EB232_RS06815	COG0126	phosphoglycerate kinase activity
EB232_RS06850	COG0450	alkyl hydroperoxide reductase
EB232_RS06855	COG3453	Protein conserved in bacteria
EB232_RS06855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EB232_RS06860	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EB232_RS06865	COG0564	pseudouridine synthase activity
EB232_RS06875	COG0346	lactoylglutathione lyase activity
EB232_RS06935	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EB232_RS06940	COG0573	inorganic phosphate transmembrane transporter activity
EB232_RS06945	COG0581	inorganic phosphate transmembrane transporter activity
EB232_RS06950	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EB232_RS06955	COG0704	Plays a role in the regulation of phosphate uptake
EB232_RS06960	COG0745	RESPONSE REGULATOR receiver
EB232_RS06965	COG1940	carbohydrate kinase activity
EB232_RS06970	COG4213	ABC transporter substrate-binding protein
EB232_RS06975	COG4214	carbohydrate transport
EB232_RS06980	COG1129	ABC transporter
EB232_RS07005	COG3920	Histidine kinase
EB232_RS07005	COG2202	Pas domain
EB232_RS07015	COG0784	Response regulator, receiver
EB232_RS07030	COG0784	Response regulator, receiver
EB232_RS07035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EB232_RS07050	COG3920	Histidine kinase
EB232_RS07060	COG1597	lipid kinase activity
EB232_RS07075	COG0346	lactoylglutathione lyase activity
EB232_RS07080	COG0400	carboxylic ester hydrolase activity
EB232_RS07100	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB232_RS07115	COG2226	methyltransferase
EB232_RS07140	COG3842	ATPase activity
EB232_RS07150	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB232_RS07160	COG4638	Rieske (2fe-2S)
EB232_RS07175	COG2199	diguanylate cyclase activity
EB232_RS07175	COG2200	EAL domain
EB232_RS07175	COG2203	Gaf domain
EB232_RS07180	COG0745	RESPONSE REGULATOR receiver
EB232_RS07185	COG0745	RESPONSE REGULATOR receiver
EB232_RS07205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EB232_RS07230	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EB232_RS07245	COG1653	transport
EB232_RS07250	COG1940	carbohydrate kinase activity
EB232_RS07250	COG1846	Transcriptional regulator
EB232_RS07255	COG0306	phosphate transporter
EB232_RS07265	COG4689	acetoacetate decarboxylase
EB232_RS07270	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS07275	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EB232_RS07285	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EB232_RS07290	COG0022	dehydrogenase e1 component
EB232_RS07290	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB232_RS07295	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB232_RS07315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EB232_RS07335	COG3732	PTS system glucitol sorbitol-specific
EB232_RS07345	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EB232_RS07355	COG2390	Transcriptional regulator
EB232_RS07365	COG1070	Carbohydrate kinase
EB232_RS07385	COG1129	ABC transporter
EB232_RS07390	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS07400	COG1082	Xylose isomerase domain protein TIM barrel
EB232_RS07410	COG2132	Multicopper oxidase
EB232_RS07520	COG4106	trans-aconitate 2-methyltransferase activity
EB232_RS07595	COG2135	peptidase activity
EB232_RS07625	COG1473	amidohydrolase
EB232_RS07635	COG0523	cobalamin synthesis protein
EB232_RS07640	COG0425	Belongs to the sulfur carrier protein TusA family
EB232_RS07650	COG0825	malonyl-CoA metabolic process
EB232_RS07655	COG4974	Belongs to the 'phage' integrase family
EB232_RS07665	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EB232_RS07670	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EB232_RS07675	COG4536	flavin adenine dinucleotide binding
EB232_RS07730	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EB232_RS07735	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EB232_RS07760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EB232_RS07765	COG2226	methyltransferase
EB232_RS07770	COG4178	(ABC) transporter
EB232_RS07780	COG1215	transferase activity, transferring glycosyl groups
EB232_RS07795	COG2813	Specifically methylates the guanine in position
EB232_RS07795	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EB232_RS07800	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EB232_RS07805	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EB232_RS07810	COG0287	Prephenate dehydrogenase
EB232_RS07875	COG2884	Cell division ATP-binding protein ftsE
EB232_RS07905	COG0583	DNA-binding transcription factor activity
EB232_RS07920	COG0019	diaminopimelate decarboxylase activity
EB232_RS07930	COG0165	Argininosuccinate lyase
EB232_RS07935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EB232_RS07940	COG5001	Diguanylate cyclase
EB232_RS07940	COG3300	MHYT domain
EB232_RS07945	COG1653	transport
EB232_RS07950	COG1175	transmembrane transport
EB232_RS07955	COG0395	ABC-type sugar transport system, permease component
EB232_RS07960	COG3842	ATPase activity
EB232_RS07965	COG3842	ATPase activity
EB232_RS07990	COG5001	Diguanylate cyclase
EB232_RS07990	COG5002	protein histidine kinase activity
EB232_RS07990	COG3447	MASE1 domain protein
EB232_RS07995	COG1250	3-hydroxyacyl-CoA dehydrogenase
EB232_RS08000	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EB232_RS08005	COG2086	electron transfer activity
EB232_RS08025	COG0300	oxidoreductase activity
EB232_RS08050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EB232_RS08100	COG0653	protein targeting
EB232_RS08105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EB232_RS08120	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EB232_RS08130	COG0494	nUDIX hydrolase
EB232_RS08145	COG2226	methyltransferase
EB232_RS08150	COG1040	competence protein
EB232_RS08160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EB232_RS08170	COG1846	Transcriptional regulator
EB232_RS08180	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EB232_RS08190	COG0527	aspartate kinase activity
EB232_RS08200	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EB232_RS08205	COG2890	protein-(glutamine-N5) methyltransferase activity
EB232_RS08215	COG0542	response to heat
EB232_RS08230	COG1376	ErfK ybiS ycfS ynhG family protein
EB232_RS08235	COG3548	integral membrane protein
EB232_RS08240	COG0477	Major facilitator Superfamily
EB232_RS08245	COG0739	heme binding
EB232_RS08280	COG3609	addiction module antidote protein, CC2985 family
EB232_RS08330	COG4372	Transposase
EB232_RS08335	COG3436	PFAM IS66 Orf2 family protein
EB232_RS08345	COG3436	PFAM IS66 Orf2 family protein
EB232_RS08365	COG2910	NAD(P)H-binding
EB232_RS08380	COG3842	ATPase activity
EB232_RS08385	COG1177	transmembrane transport
EB232_RS08390	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB232_RS08400	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS08405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB232_RS08420	COG2188	Transcriptional regulator
EB232_RS08425	COG1940	carbohydrate kinase activity
EB232_RS08440	COG1879	ABC-type sugar transport system periplasmic component
EB232_RS08445	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS08450	COG1129	ABC transporter
EB232_RS08460	COG4608	Belongs to the ABC transporter superfamily
EB232_RS08470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB232_RS08480	COG0747	negative chemotaxis
EB232_RS08495	COG5564	TIM-barrel signal transduction protein
EB232_RS08500	COG5441	Belongs to the UPF0261 family
EB232_RS08510	COG3842	ATPase activity
EB232_RS08525	COG0395	ABC-type sugar transport system, permease component
EB232_RS08530	COG3842	ATPase activity
EB232_RS08540	COG3842	ATPase activity
EB232_RS08585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EB232_RS08595	COG4948	Mandelate Racemase Muconate Lactonizing
EB232_RS08610	COG0673	inositol 2-dehydrogenase activity
EB232_RS08615	COG1082	Xylose isomerase domain protein TIM barrel
EB232_RS08620	COG3639	organic phosphonate transmembrane transporter activity
EB232_RS08635	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EB232_RS08650	COG4778	phosphonate C-P lyase system protein PhnL
EB232_RS08655	COG4107	phosphonate C-P lyase system protein PhnK
EB232_RS08660	COG3627	carbon phosphorus lyase activity
EB232_RS08670	COG3626	phosphonate metabolism
EB232_RS08675	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
EB232_RS08680	COG3624	Phosphonate C-P lyase system protein PhnG
EB232_RS08685	COG2188	Transcriptional regulator
EB232_RS08690	COG1063	alcohol dehydrogenase
EB232_RS08695	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS08705	COG1879	ABC-type sugar transport system periplasmic component
EB232_RS08715	COG2721	sulfolactate sulfo-lyase activity
EB232_RS08720	COG1802	Transcriptional regulator
EB232_RS08745	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EB232_RS08755	COG1653	transport
EB232_RS08760	COG1175	transmembrane transport
EB232_RS08765	COG0395	ABC-type sugar transport system, permease component
EB232_RS08770	COG3842	ATPase activity
EB232_RS08780	COG0673	inositol 2-dehydrogenase activity
EB232_RS08785	COG0667	Aldo Keto reductase
EB232_RS08810	COG2319	Wd-40 repeat
EB232_RS08830	COG0735	belongs to the Fur family
EB232_RS08840	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EB232_RS08840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EB232_RS08845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB232_RS08885	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS08890	COG2807	transmembrane transport
EB232_RS08900	COG2207	Transcriptional regulator
EB232_RS08905	COG4651	solute:proton antiporter activity
EB232_RS08905	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EB232_RS08910	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EB232_RS08910	COG1648	precorrin-2 dehydrogenase activity
EB232_RS08920	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EB232_RS08925	COG0175	sulfate reduction
EB232_RS08945	COG3239	Fatty acid desaturase
EB232_RS08955	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EB232_RS08960	COG2860	membrane
EB232_RS08975	COG0604	alcohol dehydrogenase
EB232_RS08980	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EB232_RS08985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EB232_RS08990	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EB232_RS08990	COG0116	Belongs to the methyltransferase superfamily
EB232_RS08995	COG2378	regulation of single-species biofilm formation
EB232_RS09020	COG0776	regulation of translation
EB232_RS09025	COG0616	signal peptide processing
EB232_RS09035	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EB232_RS09040	COG1137	ATPase activity
EB232_RS09045	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EB232_RS09050	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EB232_RS09055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EB232_RS09070	COG1957	nucleoside hydrolase
EB232_RS09080	COG1280	lysine exporter protein (LysE YggA)
EB232_RS09090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB232_RS09120	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EB232_RS09150	COG5001	Diguanylate cyclase
EB232_RS09150	COG5002	protein histidine kinase activity
EB232_RS09185	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EB232_RS09190	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EB232_RS09195	COG2226	methyltransferase
EB232_RS09200	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EB232_RS09205	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EB232_RS09215	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EB232_RS09235	COG1079	Belongs to the binding-protein-dependent transport system permease family
EB232_RS09245	COG2900	Belongs to the SlyX family
EB232_RS09260	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EB232_RS09315	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EB232_RS09325	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EB232_RS09330	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EB232_RS09335	COG2205	protein histidine kinase activity
EB232_RS09345	COG2814	Major facilitator Superfamily
EB232_RS09365	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EB232_RS09385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB232_RS09395	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB232_RS09395	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB232_RS09415	COG0673	inositol 2-dehydrogenase activity
EB232_RS09430	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS09450	COG1960	acyl-CoA dehydrogenase activity
EB232_RS09465	COG0463	Glycosyl transferase, family 2
EB232_RS09490	COG0531	amino acid
EB232_RS09525	COG3842	ATPase activity
EB232_RS09550	COG2814	Major facilitator Superfamily
EB232_RS09575	COG3842	ATPase activity
EB232_RS09580	COG0395	ABC-type sugar transport system, permease component
EB232_RS09585	COG1175	transmembrane transport
EB232_RS09590	COG1653	transport
EB232_RS09595	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS09600	COG1024	Enoyl-CoA hydratase
EB232_RS09615	COG1609	Transcriptional regulator
EB232_RS09625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EB232_RS09650	COG0483	inositol monophosphate 1-phosphatase activity
EB232_RS09675	COG0071	Belongs to the small heat shock protein (HSP20) family
EB232_RS09690	COG0067	glutamate synthase
EB232_RS09690	COG0069	glutamate synthase activity
EB232_RS09690	COG0070	glutamate synthase
EB232_RS09705	COG2951	lytic endotransglycosylase activity
EB232_RS09710	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EB232_RS09735	COG0330	HflC and HflK could
EB232_RS09745	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EB232_RS09750	COG0737	Belongs to the 5'-nucleotidase family
EB232_RS09760	COG5310	Homospermidine synthase
EB232_RS09785	COG3743	rRNA binding
EB232_RS09785	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EB232_RS09795	COG2204	response regulator
EB232_RS09800	COG3108	Peptidase M15
EB232_RS09805	COG0800	Aldolase
EB232_RS09820	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS09825	COG3795	YCII-related domain
EB232_RS09850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EB232_RS09865	COG0583	DNA-binding transcription factor activity
EB232_RS09870	COG0154	amidase activity
EB232_RS09910	COG0644	oxidoreductase
EB232_RS09935	COG1136	(ABC) transporter
EB232_RS09940	COG0577	efflux transmembrane transporter activity
EB232_RS09940	COG1136	(ABC) transporter
EB232_RS09990	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EB232_RS10030	COG2814	Major facilitator Superfamily
EB232_RS10035	COG0367	asparagine synthase
EB232_RS10045	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EB232_RS10050	COG5443	negative regulation of bacterial-type flagellum assembly
EB232_RS10070	COG1749	Flagellar hook protein flgE
EB232_RS10110	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EB232_RS10115	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EB232_RS10120	COG1338	Plays a role in the flagellum-specific transport system
EB232_RS10130	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EB232_RS10140	COG1706	bacterial-type flagellum-dependent cell motility
EB232_RS10145	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
EB232_RS10150	COG4786	Flagellar basal body rod
EB232_RS10155	COG1677	Flagellar hook-basal body complex protein FliE
EB232_RS10160	COG1558	bacterial-type flagellum-dependent cell motility
EB232_RS10165	COG1815	bacterial-type flagellum-dependent cell motility
EB232_RS10175	COG1157	protein secretion by the type III secretion system
EB232_RS10180	COG4786	Flagellar basal body rod
EB232_RS10190	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EB232_RS10195	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EB232_RS10200	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EB232_RS10205	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EB232_RS10210	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EB232_RS10225	COG2771	luxR family
EB232_RS10230	COG0612	Peptidase, M16
EB232_RS10250	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EB232_RS10255	COG3842	ATPase activity
EB232_RS10260	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB232_RS10265	COG1177	transmembrane transport
EB232_RS10270	COG1840	ABC-type Fe3 transport system, periplasmic component
EB232_RS10285	COG2183	response to ionizing radiation
EB232_RS10290	COG0583	DNA-binding transcription factor activity
EB232_RS10295	COG1960	acyl-CoA dehydrogenase activity
EB232_RS10310	COG1305	Transglutaminase-like
EB232_RS10320	COG1215	transferase activity, transferring glycosyl groups
EB232_RS10335	COG3795	YCII-related domain
EB232_RS10340	COG4941	Belongs to the sigma-70 factor family
EB232_RS10345	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS10375	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS10395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EB232_RS10410	COG2207	Transcriptional regulator
EB232_RS10410	COG0662	Cupin 2, conserved barrel domain protein
EB232_RS10470	COG1335	isochorismatase
EB232_RS10500	COG0583	DNA-binding transcription factor activity
EB232_RS10550	COG5001	Diguanylate cyclase
EB232_RS10550	COG3300	MHYT domain
EB232_RS10560	COG3547	Transposase (IS116 IS110 IS902 family)
EB232_RS10570	COG3547	Transposase (IS116 IS110 IS902 family)
EB232_RS10580	COG0475	glutathione-regulated potassium exporter activity
EB232_RS10605	COG4957	zinc ion binding
EB232_RS10670	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EB232_RS10680	COG3842	ATPase activity
EB232_RS10685	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB232_RS10690	COG1177	transmembrane transport
EB232_RS10695	COG0583	DNA-binding transcription factor activity
EB232_RS10715	COG0583	DNA-binding transcription factor activity
EB232_RS10725	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB232_RS10735	COG3842	ATPase activity
EB232_RS10755	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB232_RS10755	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB232_RS10765	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EB232_RS10770	COG1760	l-serine dehydratase
EB232_RS10785	COG2801	Transposase and inactivated derivatives
EB232_RS10795	COG0726	polysaccharide deacetylase
EB232_RS10800	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS10805	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS10825	COG0559	Belongs to the binding-protein-dependent transport system permease family
EB232_RS10845	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EB232_RS10855	COG0747	negative chemotaxis
EB232_RS10860	COG0601	transmembrane transport
EB232_RS10870	COG4172	Belongs to the ABC transporter superfamily
EB232_RS10925	COG4208	sulfate ABC transporter
EB232_RS10930	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB232_RS10940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB232_RS10950	COG3842	ATPase activity
EB232_RS10955	COG0583	DNA-binding transcription factor activity
EB232_RS10980	COG0395	ABC-type sugar transport system, permease component
EB232_RS10985	COG0673	inositol 2-dehydrogenase activity
EB232_RS10995	COG3963	phosphatidate phosphatase activity
EB232_RS11015	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EB232_RS11050	COG1609	Transcriptional regulator
EB232_RS11055	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EB232_RS11070	COG1129	ABC transporter
EB232_RS11075	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS11095	COG1396	sequence-specific DNA binding
EB232_RS11105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB232_RS11110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB232_RS11120	COG1116	anion transmembrane transporter activity
EB232_RS11140	COG3604	Transcriptional regulator
EB232_RS11150	COG3842	ATPase activity
EB232_RS11155	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB232_RS11160	COG1177	transmembrane transport
EB232_RS11165	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS11175	COG1129	ABC transporter
EB232_RS11180	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS11185	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS11205	COG1879	ABC-type sugar transport system periplasmic component
EB232_RS11210	COG1879	ABC-type sugar transport system periplasmic component
EB232_RS11215	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS11230	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS11235	COG0022	dehydrogenase e1 component
EB232_RS11240	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EB232_RS11245	COG1414	Transcriptional regulator
EB232_RS11250	COG3842	ATPase activity
EB232_RS11260	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB232_RS11280	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS11290	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EB232_RS11300	COG3246	L-lysine catabolic process to acetate
EB232_RS11315	COG0583	DNA-binding transcription factor activity
EB232_RS11320	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS11330	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB232_RS11340	COG3842	ATPase activity
EB232_RS11345	COG0318	PFAM AMP-dependent synthetase and ligase
EB232_RS11350	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EB232_RS11360	COG0667	Aldo Keto reductase
EB232_RS11370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EB232_RS11375	COG0546	phosphoglycolate phosphatase activity
EB232_RS11395	COG1850	ribulose-bisphosphate carboxylase activity
EB232_RS11405	COG0126	phosphoglycerate kinase activity
EB232_RS11415	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EB232_RS11425	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EB232_RS11430	COG0583	DNA-binding transcription factor activity
EB232_RS11435	COG2204	response regulator
EB232_RS11490	COG0316	Belongs to the HesB IscA family
EB232_RS11490	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EB232_RS11525	COG0375	protein maturation
EB232_RS11535	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EB232_RS11570	COG3436	PFAM IS66 Orf2 family protein
EB232_RS11575	COG4372	Transposase
EB232_RS11595	COG1349	DNA-binding transcription factor activity
EB232_RS11615	COG3842	ATPase activity
EB232_RS11635	COG0156	8-amino-7-oxononanoate synthase activity
EB232_RS11640	COG1063	alcohol dehydrogenase
EB232_RS11645	COG1283	sodium-dependent phosphate transmembrane transporter activity
EB232_RS11675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EB232_RS11700	COG0626	cystathionine gamma-synthase activity
EB232_RS11725	COG5383	Protein conserved in bacteria
EB232_RS11735	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS11740	COG0436	Aminotransferase
EB232_RS11745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB232_RS11750	COG4957	zinc ion binding
EB232_RS11765	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EB232_RS11790	COG1396	sequence-specific DNA binding
EB232_RS11805	COG0673	inositol 2-dehydrogenase activity
EB232_RS11810	COG0482	sulfurtransferase activity
EB232_RS11825	COG1733	regulation of RNA biosynthetic process
EB232_RS11840	COG2201	protein-glutamate methylesterase activity
EB232_RS11860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EB232_RS11885	COG0435	Glutathione S-transferase
EB232_RS11915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EB232_RS11930	COG0477	Major facilitator Superfamily
EB232_RS11935	COG0583	DNA-binding transcription factor activity
EB232_RS11945	COG3180	Ammonia monooxygenase
EB232_RS11955	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS11975	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EB232_RS11980	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EB232_RS11980	COG0512	Glutamine amidotransferase of anthranilate synthase
EB232_RS11985	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EB232_RS11995	COG2814	Major facilitator Superfamily
EB232_RS12000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EB232_RS12020	COG1335	isochorismatase
EB232_RS12025	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EB232_RS12065	COG1435	thymidine kinase activity
EB232_RS12075	COG4176	ABC-type proline glycine betaine transport system permease component
EB232_RS12085	COG2205	protein histidine kinase activity
EB232_RS12090	COG0745	RESPONSE REGULATOR receiver
EB232_RS12110	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EB232_RS12130	COG0714	Associated with various cellular activities
EB232_RS12145	COG0617	tRNA 3'-terminal CCA addition
EB232_RS12165	COG0408	coproporphyrinogen oxidase activity
EB232_RS12175	COG0789	Transcriptional regulator
EB232_RS12180	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EB232_RS12190	COG1132	(ABC) transporter
EB232_RS12195	COG1132	(ABC) transporter
EB232_RS12225	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EB232_RS12225	COG2857	Cytochrome c1
EB232_RS12240	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EB232_RS12265	COG0012	GTP binding
EB232_RS12270	COG0193	aminoacyl-tRNA hydrolase activity
EB232_RS12275	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EB232_RS12290	COG1846	Transcriptional regulator
EB232_RS12300	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS12305	COG2223	nitrite transmembrane transporter activity
EB232_RS12310	COG2207	Transcriptional regulator
EB232_RS12315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EB232_RS12340	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EB232_RS12365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EB232_RS12380	COG2205	protein histidine kinase activity
EB232_RS12385	COG0745	RESPONSE REGULATOR receiver
EB232_RS12390	COG1846	Transcriptional regulator
EB232_RS12395	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EB232_RS12405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EB232_RS12415	COG1278	Cold shock
EB232_RS12420	COG1278	Cold shock
EB232_RS12450	COG1278	Cold shock
EB232_RS12500	COG0556	nucleotide-excision repair
EB232_RS12510	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EB232_RS12530	COG0583	DNA-binding transcription factor activity
EB232_RS12535	COG2175	clavaminate synthase activity
EB232_RS12560	COG0277	FAD linked oxidase domain protein
EB232_RS12590	COG1597	lipid kinase activity
EB232_RS12595	COG2084	Dehydrogenase
EB232_RS12610	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EB232_RS12615	COG1607	acyl-coa hydrolase
EB232_RS12665	COG1253	flavin adenine dinucleotide binding
EB232_RS12675	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EB232_RS12700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EB232_RS12705	COG0859	PFAM glycosyl transferase family 9
EB232_RS12715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EB232_RS12735	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EB232_RS12735	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EB232_RS12740	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EB232_RS12745	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EB232_RS12750	COG0463	Glycosyl transferase, family 2
EB232_RS12755	COG1522	sequence-specific DNA binding
EB232_RS12760	COG0492	ferredoxin-NADP+ reductase activity
EB232_RS12765	COG0583	DNA-binding transcription factor activity
EB232_RS12775	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EB232_RS12790	COG0436	Aminotransferase
EB232_RS12800	COG3300	MHYT domain
EB232_RS12800	COG5001	Diguanylate cyclase
EB232_RS12805	COG0625	glutathione transferase activity
EB232_RS12810	COG1278	Cold shock
EB232_RS12830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EB232_RS12850	COG3755	Protein conserved in bacteria
EB232_RS12860	COG2852	Protein conserved in bacteria
EB232_RS12880	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EB232_RS12900	COG2814	Major facilitator Superfamily
EB232_RS12910	COG4221	oxidoreductase activity
EB232_RS12920	COG2801	Transposase and inactivated derivatives
EB232_RS12940	COG1914	H( )-stimulated, divalent metal cation uptake system
EB232_RS12945	COG1321	iron dependent repressor
EB232_RS12960	COG2321	neutral zinc metallopeptidase
EB232_RS12970	COG4989	oxidoreductase activity
EB232_RS12985	COG0505	Belongs to the CarA family
EB232_RS13005	COG0789	Transcriptional regulator
EB232_RS13015	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS13020	COG0583	DNA-binding transcription factor activity
EB232_RS13025	COG2814	Major facilitator Superfamily
EB232_RS13055	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EB232_RS13085	COG1695	Transcriptional regulator
EB232_RS13125	COG1595	DNA-templated transcription, initiation
EB232_RS13145	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS13160	COG0673	inositol 2-dehydrogenase activity
EB232_RS13170	COG1522	sequence-specific DNA binding
EB232_RS13185	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EB232_RS13190	COG0583	DNA-binding transcription factor activity
EB232_RS13205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EB232_RS13210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EB232_RS13215	COG2197	response regulator
EB232_RS13220	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS13225	COG2862	Uncharacterized protein family, UPF0114
EB232_RS13235	COG2983	Belongs to the UPF0260 family
EB232_RS13245	COG2968	Membrane
EB232_RS13290	COG1850	ribulose-bisphosphate carboxylase activity
EB232_RS13305	COG0673	inositol 2-dehydrogenase activity
EB232_RS13310	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS13315	COG1129	ABC transporter
EB232_RS13325	COG1879	ABC-type sugar transport system periplasmic component
EB232_RS13330	COG0287	Prephenate dehydrogenase
EB232_RS13335	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS13340	COG1129	ABC transporter
EB232_RS13345	COG1879	ABC-type sugar transport system periplasmic component
EB232_RS13350	COG0583	DNA-binding transcription factor activity
EB232_RS13380	COG1902	pentaerythritol trinitrate reductase activity
EB232_RS13385	COG1609	Transcriptional regulator
EB232_RS13390	COG1063	alcohol dehydrogenase
EB232_RS13395	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS13405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB232_RS13410	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
EB232_RS13435	COG4608	Belongs to the ABC transporter superfamily
EB232_RS13450	COG5598	trimethylamine methyltransferase
EB232_RS13465	COG1454	alcohol dehydrogenase
EB232_RS13470	COG3485	protocatechuate 3,4-dioxygenase
EB232_RS13475	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS13480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EB232_RS13485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB232_RS13510	COG3454	Phosphonate metabolism
EB232_RS13535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB232_RS13550	COG5001	Diguanylate cyclase
EB232_RS13550	COG3300	MHYT domain
EB232_RS13555	COG1473	amidohydrolase
EB232_RS13575	COG2080	2 iron, 2 sulfur cluster binding
EB232_RS13575	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EB232_RS13610	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EB232_RS13665	COG4372	Transposase
EB232_RS13670	COG3436	PFAM IS66 Orf2 family protein
EB232_RS13690	COG2885	chlorophyll binding
EB232_RS13690	COG3047	cAMP biosynthetic process
EB232_RS13745	COG0784	Response regulator, receiver
EB232_RS13745	COG4191	Histidine kinase
EB232_RS13795	COG0346	lactoylglutathione lyase activity
EB232_RS13815	COG0395	ABC-type sugar transport system, permease component
EB232_RS13820	COG1175	transmembrane transport
EB232_RS13830	COG1609	Transcriptional regulator
EB232_RS13865	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EB232_RS13870	COG0459	protein refolding
EB232_RS13880	COG2818	Glycosylase
EB232_RS13890	COG4221	oxidoreductase activity
EB232_RS13895	COG2207	Transcriptional regulator
EB232_RS13910	COG1956	GAF domain-containing protein
EB232_RS13930	COG3794	PFAM blue (type 1) copper domain protein
EB232_RS13935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EB232_RS13950	COG2855	membrane
EB232_RS13955	COG0110	maltose O-acetyltransferase activity
EB232_RS13985	COG0667	Aldo Keto reductase
EB232_RS13990	COG0400	carboxylic ester hydrolase activity
EB232_RS14000	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EB232_RS14035	COG1902	pentaerythritol trinitrate reductase activity
EB232_RS14060	COG3609	addiction module antidote protein, CC2985 family
EB232_RS14075	COG0765	amino acid transport
EB232_RS14120	COG0110	maltose O-acetyltransferase activity
EB232_RS14135	COG0406	alpha-ribazole phosphatase activity
EB232_RS14255	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB232_RS14260	COG0640	Transcriptional regulator
EB232_RS14265	COG0667	Aldo Keto reductase
EB232_RS14270	COG0583	DNA-binding transcription factor activity
EB232_RS14275	COG4251	negative regulation of phosphorylation
EB232_RS14275	COG5001	Diguanylate cyclase
EB232_RS14275	COG2203	Gaf domain
EB232_RS14275	COG3706	GGDEF domain
EB232_RS14290	COG0798	PFAM Bile acid sodium symporter
EB232_RS14305	COG0492	ferredoxin-NADP+ reductase activity
EB232_RS14350	COG1129	ABC transporter
EB232_RS14355	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS14410	COG3756	Protein conserved in bacteria
EB232_RS14430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EB232_RS14440	COG1177	transmembrane transport
EB232_RS14445	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB232_RS14455	COG3842	ATPase activity
EB232_RS14460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB232_RS14475	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS14480	COG0604	alcohol dehydrogenase
EB232_RS14600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EB232_RS14605	COG1609	Transcriptional regulator
EB232_RS14620	COG0489	protein tyrosine kinase activity
EB232_RS14620	COG3206	protein involved in exopolysaccharide biosynthesis
EB232_RS14640	COG0297	glycogen (starch) synthase activity
EB232_RS14685	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EB232_RS14780	COG0625	glutathione transferase activity
EB232_RS14785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EB232_RS14825	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS14840	COG0488	(ABC) transporter
EB232_RS14860	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EB232_RS14875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EB232_RS14880	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EB232_RS14890	COG3842	ATPase activity
EB232_RS14900	COG1177	transmembrane transport
EB232_RS14905	COG0395	ABC-type sugar transport system, permease component
EB232_RS14910	COG0326	Molecular chaperone. Has ATPase activity
EB232_RS14920	COG0583	DNA-binding transcription factor activity
EB232_RS14930	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS14975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EB232_RS14980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EB232_RS14995	COG0583	DNA-binding transcription factor activity
EB232_RS15000	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS15075	COG0697	spore germination
EB232_RS15100	COG0850	regulation of cytokinetic process
EB232_RS15105	COG2894	cell division
EB232_RS15110	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EB232_RS15130	COG2205	protein histidine kinase activity
EB232_RS15160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB232_RS15165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EB232_RS15180	COG3920	Histidine kinase
EB232_RS15185	COG5006	permease, DMT superfamily
EB232_RS15215	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EB232_RS15220	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EB232_RS15225	COG2080	2 iron, 2 sulfur cluster binding
EB232_RS15230	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EB232_RS15235	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EB232_RS15240	COG2080	2 iron, 2 sulfur cluster binding
EB232_RS15245	COG1309	transcriptional regulator
EB232_RS15260	COG1349	DNA-binding transcription factor activity
EB232_RS15265	COG1129	ABC transporter
EB232_RS15270	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS15285	COG1064	alcohol dehydrogenase
EB232_RS15295	COG0604	alcohol dehydrogenase
EB232_RS15320	COG0656	L-ascorbic acid biosynthetic process
EB232_RS15340	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EB232_RS15400	COG2226	methyltransferase
EB232_RS15405	COG0596	Alpha beta hydrolase
EB232_RS15415	COG2072	flavoprotein involved in K transport
EB232_RS15495	COG1162	GTPase activity
EB232_RS15500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EB232_RS15525	COG0596	Alpha beta hydrolase
EB232_RS15540	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EB232_RS15540	COG2169	Transcriptional regulator
EB232_RS15550	COG2169	Transcriptional regulator
EB232_RS15550	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EB232_RS15555	COG1733	regulation of RNA biosynthetic process
EB232_RS15580	COG5001	Diguanylate cyclase
EB232_RS15580	COG5002	protein histidine kinase activity
EB232_RS15590	COG3468	outer membrane autotransporter barrel domain protein
EB232_RS15600	COG0318	PFAM AMP-dependent synthetase and ligase
EB232_RS15605	COG1024	Enoyl-CoA hydratase
EB232_RS15630	COG0583	DNA-binding transcription factor activity
EB232_RS15635	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS15645	COG5001	Diguanylate cyclase
EB232_RS15660	COG1522	sequence-specific DNA binding
EB232_RS15695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB232_RS15700	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EB232_RS15720	COG1181	Belongs to the D-alanine--D-alanine ligase family
EB232_RS15725	COG0628	permease
EB232_RS15730	COG0583	DNA-binding transcription factor activity
EB232_RS15735	COG2514	catechol 2,3-dioxygenase activity
EB232_RS15755	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EB232_RS15770	COG0667	Aldo Keto reductase
EB232_RS15785	COG3852	Histidine kinase
EB232_RS15895	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EB232_RS15910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB232_RS15915	COG1116	anion transmembrane transporter activity
EB232_RS15955	COG1397	ADP-ribosylglycohydrolase
EB232_RS15960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB232_RS15965	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EB232_RS15975	COG1177	transmembrane transport
EB232_RS15980	COG3842	ATPase activity
EB232_RS15990	COG0583	DNA-binding transcription factor activity
EB232_RS16015	COG2986	histidine ammonia-lyase
EB232_RS16025	COG2814	Major facilitator Superfamily
EB232_RS16030	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS16040	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS16050	COG1129	ABC transporter
EB232_RS16070	COG3842	ATPase activity
EB232_RS16075	COG1175	transmembrane transport
EB232_RS16100	COG0542	response to heat
EB232_RS16110	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EB232_RS16130	COG1917	Cupin 2, conserved barrel domain protein
EB232_RS16130	COG2169	Transcriptional regulator
EB232_RS16135	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS16140	COG1129	ABC transporter
EB232_RS16150	COG2186	Transcriptional regulator
EB232_RS16160	COG1086	Polysaccharide biosynthesis protein
EB232_RS16170	COG2271	Major facilitator Superfamily
EB232_RS16175	COG1609	Transcriptional regulator
EB232_RS16180	COG1879	ABC-type sugar transport system periplasmic component
EB232_RS16185	COG1129	ABC transporter
EB232_RS16190	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS16195	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS16200	COG3265	gluconokinase activity
EB232_RS16210	COG1959	2 iron, 2 sulfur cluster binding
EB232_RS16215	COG4150	thiosulfate binding
EB232_RS16230	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EB232_RS16235	COG4208	sulfate ABC transporter
EB232_RS16240	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EB232_RS16245	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EB232_RS16255	COG4953	penicillin-binding protein 1C
EB232_RS16260	COG2373	Large extracellular alpha-helical protein
EB232_RS16265	COG0729	surface antigen
EB232_RS16280	COG0601	transmembrane transport
EB232_RS16285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB232_RS16300	COG5598	trimethylamine methyltransferase
EB232_RS16325	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EB232_RS16330	COG0493	'glutamate synthase
EB232_RS16350	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EB232_RS16360	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS16375	COG1309	transcriptional regulator
EB232_RS16420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB232_RS16425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB232_RS16430	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EB232_RS16440	COG0028	Belongs to the TPP enzyme family
EB232_RS16445	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EB232_RS16450	COG2826	transposase and inactivated derivatives, IS30 family
EB232_RS16470	COG3706	GGDEF domain
EB232_RS16480	COG4106	trans-aconitate 2-methyltransferase activity
EB232_RS16500	COG2020	methyltransferase activity
EB232_RS16515	COG1309	transcriptional regulator
EB232_RS16525	COG4221	oxidoreductase activity
EB232_RS16530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EB232_RS16545	COG1720	tRNA m6t6A37 methyltransferase activity
EB232_RS16590	COG2226	methyltransferase
EB232_RS16620	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EB232_RS16625	COG3023	N-Acetylmuramoyl-L-alanine amidase
EB232_RS16640	COG0626	cystathionine gamma-synthase activity
EB232_RS16645	COG2001	Belongs to the MraZ family
EB232_RS16650	COG0275	rRNA processing
EB232_RS16665	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EB232_RS16675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EB232_RS16680	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EB232_RS16690	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EB232_RS16695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EB232_RS16700	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EB232_RS16705	COG1181	Belongs to the D-alanine--D-alanine ligase family
EB232_RS16710	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EB232_RS16715	COG0849	cell division
EB232_RS16720	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EB232_RS16730	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EB232_RS16740	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EB232_RS16760	COG0006	proline dipeptidase activity
EB232_RS16765	COG2264	protein methyltransferase activity
EB232_RS16770	COG1999	signal sequence binding
EB232_RS16775	COG3038	cytochrome b561
EB232_RS16815	COG0534	Mate efflux family protein
EB232_RS16835	COG5598	trimethylamine methyltransferase
EB232_RS16840	COG1116	anion transmembrane transporter activity
EB232_RS16855	COG4566	intracellular signal transduction
EB232_RS16860	COG4191	Histidine kinase
EB232_RS16875	COG1609	Transcriptional regulator
EB232_RS16905	COG0210	DNA helicase
EB232_RS16935	COG0784	Response regulator, receiver
EB232_RS16940	COG4191	Histidine kinase
EB232_RS16940	COG0784	Response regulator, receiver
EB232_RS16960	COG0277	FAD linked oxidase domain protein
EB232_RS16985	COG2837	iron assimilation
EB232_RS17025	COG2814	Major facilitator Superfamily
EB232_RS17040	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EB232_RS17045	COG3585	molybdate ion transport
EB232_RS17050	COG0725	ABC transporter, periplasmic molybdate-binding protein
EB232_RS17055	COG4149	molybdate abc transporter
EB232_RS17060	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EB232_RS17065	COG2005	Transcriptional regulator
EB232_RS17065	COG3585	molybdate ion transport
EB232_RS17070	COG1879	ABC-type sugar transport system periplasmic component
EB232_RS17075	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS17080	COG1129	ABC transporter
EB232_RS17090	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EB232_RS17100	COG1070	Carbohydrate kinase
EB232_RS17120	COG0330	HflC and HflK could
EB232_RS17125	COG0330	HflC and HflK could
EB232_RS17145	COG3830	Belongs to the UPF0237 family
EB232_RS17145	COG0560	Phosphoserine phosphatase
EB232_RS17150	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EB232_RS17155	COG2199	diguanylate cyclase activity
EB232_RS17155	COG2203	Gaf domain
EB232_RS17165	COG1396	sequence-specific DNA binding
EB232_RS17185	COG2175	clavaminate synthase activity
EB232_RS17200	COG0028	Belongs to the TPP enzyme family
EB232_RS17210	COG0640	Transcriptional regulator
EB232_RS17225	COG0590	tRNA wobble adenosine to inosine editing
EB232_RS17230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB232_RS17260	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EB232_RS17270	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EB232_RS17275	COG3158	transport of potassium into the cell
EB232_RS17280	COG3158	transport of potassium into the cell
EB232_RS17285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EB232_RS17295	COG1733	regulation of RNA biosynthetic process
EB232_RS17300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EB232_RS17320	COG1309	transcriptional regulator
EB232_RS17325	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EB232_RS17360	COG2826	transposase and inactivated derivatives, IS30 family
EB232_RS17365	COG0697	spore germination
EB232_RS17370	COG0577	efflux transmembrane transporter activity
EB232_RS17370	COG1136	(ABC) transporter
EB232_RS17375	COG0577	efflux transmembrane transporter activity
EB232_RS17375	COG1136	(ABC) transporter
EB232_RS17385	COG0384	phenazine biosynthesis protein PhzF
EB232_RS17400	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EB232_RS17405	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EB232_RS17410	COG1797	cobyrinic acid a,c-diamide synthase activity
EB232_RS17475	COG3214	Protein conserved in bacteria
EB232_RS17485	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EB232_RS17490	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EB232_RS17495	COG0649	NAD binding
EB232_RS17500	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EB232_RS17505	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EB232_RS17510	COG3743	rRNA binding
EB232_RS17510	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EB232_RS17520	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EB232_RS17525	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EB232_RS17535	COG0713	ATP synthesis coupled electron transport
EB232_RS17550	COG1007	ATP synthesis coupled electron transport
EB232_RS17570	COG0346	lactoylglutathione lyase activity
EB232_RS17585	COG0442	prolyl-tRNA aminoacylation
EB232_RS17595	COG1136	(ABC) transporter
EB232_RS17605	COG0321	lipoyl(octanoyl) transferase activity
EB232_RS17715	COG3750	Belongs to the UPF0335 family
EB232_RS17965	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EB232_RS17970	COG0045	succinate-CoA ligase (ADP-forming) activity
EB232_RS17975	COG2301	Belongs to the HpcH HpaI aldolase family
EB232_RS17990	COG2239	Acts as a magnesium transporter
EB232_RS18060	COG0251	oxidation-reduction process
EB232_RS18075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB232_RS18080	COG0402	S-adenosylhomocysteine deaminase activity
EB232_RS18090	COG2249	NAD(P)H dehydrogenase (quinone) activity
EB232_RS18095	COG2249	NAD(P)H dehydrogenase (quinone) activity
EB232_RS18110	COG2040	homocysteine
EB232_RS18130	COG2814	Major facilitator Superfamily
EB232_RS18140	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB232_RS18140	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB232_RS18150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB232_RS18155	COG3264	Mechanosensitive ion channel
EB232_RS18155	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EB232_RS18165	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EB232_RS18180	COG1088	dTDP-glucose 4,6-dehydratase activity
EB232_RS18220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB232_RS18240	COG0583	DNA-binding transcription factor activity
EB232_RS18260	COG1410	methionine synthase
EB232_RS18260	COG0646	methionine synthase
EB232_RS18300	COG5012	cobalamin binding
EB232_RS18305	COG5598	trimethylamine methyltransferase
EB232_RS18315	COG2186	Transcriptional regulator
EB232_RS18320	COG2807	transmembrane transport
EB232_RS18330	COG2081	HI0933 family
EB232_RS18340	COG2304	oxidoreductase activity
EB232_RS18350	COG1410	methionine synthase
EB232_RS18350	COG0646	methionine synthase
EB232_RS18380	COG0006	proline dipeptidase activity
EB232_RS18415	COG1505	serine-type exopeptidase activity
EB232_RS18440	COG1960	acyl-CoA dehydrogenase activity
EB232_RS18450	COG1492	cobalamin metabolic process
EB232_RS18480	COG4172	Belongs to the ABC transporter superfamily
EB232_RS18490	COG0601	transmembrane transport
EB232_RS18495	COG0747	negative chemotaxis
EB232_RS18500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB232_RS18520	COG1063	alcohol dehydrogenase
EB232_RS18525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EB232_RS18530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EB232_RS18535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EB232_RS18580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB232_RS18590	COG1858	cytochrome C peroxidase
EB232_RS18595	COG1522	sequence-specific DNA binding
EB232_RS18605	COG1215	transferase activity, transferring glycosyl groups
EB232_RS18630	COG3720	iron ion transport
EB232_RS18635	COG4558	Periplasmic binding protein
EB232_RS18640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EB232_RS18645	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EB232_RS18650	COG1959	2 iron, 2 sulfur cluster binding
EB232_RS18655	COG2733	membrane
EB232_RS18675	COG0583	DNA-binding transcription factor activity
EB232_RS18680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB232_RS18685	COG0697	spore germination
EB232_RS18710	COG5002	protein histidine kinase activity
EB232_RS18750	COG3142	Participates in the control of copper homeostasis
EB232_RS18790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EB232_RS18830	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EB232_RS18835	COG3119	arylsulfatase activity
EB232_RS18905	COG3338	carbonate dehydratase activity
EB232_RS18915	COG3436	PFAM IS66 Orf2 family protein
EB232_RS18920	COG4372	Transposase
EB232_RS18925	COG0668	transmembrane transport
EB232_RS18935	COG1376	ErfK ybiS ycfS ynhG family protein
EB232_RS18955	COG1525	nuclease
EB232_RS19035	COG4372	Transposase
EB232_RS19040	COG3436	PFAM IS66 Orf2 family protein
EB232_RS19080	COG0384	phenazine biosynthesis protein PhzF
EB232_RS19100	COG2135	peptidase activity
EB232_RS19185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EB232_RS19195	COG1047	Peptidyl-prolyl cis-trans
EB232_RS19240	COG0484	heat shock protein binding
EB232_RS19270	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EB232_RS19285	COG0525	valine-tRNA ligase activity
EB232_RS19295	COG0129	dihydroxy-acid dehydratase activity
EB232_RS19310	COG0708	Exodeoxyribonuclease III
EB232_RS19325	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EB232_RS19330	COG0018	arginyl-trna synthetase
EB232_RS19345	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EB232_RS19350	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EB232_RS19355	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EB232_RS19360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EB232_RS19365	COG0805	protein transport
EB232_RS19370	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EB232_RS19375	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EB232_RS19380	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EB232_RS19400	COG1862	Preprotein translocase
EB232_RS19430	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EB232_RS19460	COG0544	peptidyl-prolyl cis-trans isomerase activity
EB232_RS19480	COG2003	Belongs to the UPF0758 family
EB232_RS19490	COG0604	alcohol dehydrogenase
EB232_RS19510	COG0697	spore germination
EB232_RS19630	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EB232_RS19645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EB232_RS19670	COG2814	Major facilitator Superfamily
EB232_RS19685	COG2080	2 iron, 2 sulfur cluster binding
EB232_RS19690	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EB232_RS19695	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EB232_RS19705	COG0561	phosphatase activity
EB232_RS19710	COG3685	Protein conserved in bacteria
EB232_RS19715	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS19745	COG1309	transcriptional regulator
EB232_RS19755	COG4993	Dehydrogenase
EB232_RS19765	COG0437	4 iron, 4 sulfur cluster binding
EB232_RS19805	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EB232_RS19840	COG0024	Methionine aminopeptidase
EB232_RS19920	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EB232_RS19980	COG3243	poly(R)-hydroxyalkanoic acid synthase
EB232_RS19990	COG0436	Aminotransferase
EB232_RS20010	COG1494	fructose-1,6-bisphosphatase
EB232_RS20025	COG1752	Esterase of the alpha-beta hydrolase superfamily
EB232_RS20030	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EB232_RS20035	COG0302	gtp cyclohydrolase
EB232_RS20050	COG0583	DNA-binding transcription factor activity
EB232_RS20060	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EB232_RS20070	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EB232_RS20075	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EB232_RS20090	COG0778	Nitroreductase
EB232_RS20105	COG2301	Belongs to the HpcH HpaI aldolase family
EB232_RS20110	COG2030	dehydratase
EB232_RS20125	COG0187	DNA topoisomerase II activity
EB232_RS20135	COG4964	Belongs to the GSP D family
EB232_RS20165	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EB232_RS20165	COG2755	lipolytic protein G-D-S-L family
EB232_RS20185	COG3706	GGDEF domain
EB232_RS20190	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EB232_RS20190	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EB232_RS20195	COG0509	glycine decarboxylation via glycine cleavage system
EB232_RS20200	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB232_RS20215	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EB232_RS20230	COG1671	Belongs to the UPF0178 family
EB232_RS20235	COG3791	Glutathione-dependent formaldehyde-activating
EB232_RS20240	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EB232_RS20245	COG4770	biotin carboxylase activity
EB232_RS20265	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EB232_RS20290	COG0784	Response regulator, receiver
EB232_RS20300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EB232_RS20305	COG4977	sequence-specific DNA binding
EB232_RS20315	COG2186	Transcriptional regulator
EB232_RS20320	COG0626	cystathionine gamma-synthase activity
EB232_RS20335	COG0395	ABC-type sugar transport system, permease component
EB232_RS20340	COG3842	ATPase activity
EB232_RS20345	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EB232_RS20370	COG0557	exoribonuclease II activity
EB232_RS20375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EB232_RS20385	COG0785	Cytochrome C biogenesis protein
EB232_RS20390	COG2814	Major facilitator Superfamily
EB232_RS20395	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EB232_RS20405	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EB232_RS20415	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EB232_RS20425	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EB232_RS20430	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EB232_RS20435	COG3706	GGDEF domain
EB232_RS20445	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EB232_RS20480	COG1132	(ABC) transporter
EB232_RS20490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EB232_RS20500	COG0280	phosphate acetyltransferase
EB232_RS20500	COG0281	malic enzyme
EB232_RS20520	COG4948	Mandelate Racemase Muconate Lactonizing
EB232_RS20525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EB232_RS20530	COG1127	ABC transporter
EB232_RS20565	COG0633	Ferredoxin
EB232_RS20570	COG0492	ferredoxin-NADP+ reductase activity
EB232_RS20585	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EB232_RS20590	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EB232_RS20595	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EB232_RS20605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EB232_RS20605	COG0475	glutathione-regulated potassium exporter activity
EB232_RS20620	COG3768	UPF0283 membrane protein
EB232_RS20625	COG3106	COG3106 Predicted ATPase
EB232_RS20650	COG0813	purine-nucleoside phosphorylase activity
EB232_RS20715	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EB232_RS20725	COG0740	serine-type endopeptidase activity
EB232_RS20740	COG0629	single-stranded DNA binding
EB232_RS20745	COG1765	OsmC-like protein
EB232_RS20750	COG2095	MarC family integral membrane protein
EB232_RS20780	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EB232_RS20790	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EB232_RS20810	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EB232_RS20820	COG0343	queuine tRNA-ribosyltransferase activity
EB232_RS20840	COG2308	Evidence 4 Homologs of previously reported genes of
EB232_RS20895	COG0395	ABC-type sugar transport system, permease component
EB232_RS20910	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EB232_RS20930	COG3436	PFAM IS66 Orf2 family protein
EB232_RS20935	COG4372	Transposase
EB232_RS20950	COG3547	Transposase (IS116 IS110 IS902 family)
EB232_RS20960	COG3547	Transposase (IS116 IS110 IS902 family)
EB232_RS20985	COG0438	transferase activity, transferring glycosyl groups
EB232_RS21005	COG0758	DNA mediated transformation
EB232_RS21010	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EB232_RS21015	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EB232_RS21020	COG0540	Belongs to the ATCase OTCase family
EB232_RS21025	COG1960	acyl-CoA dehydrogenase activity
EB232_RS21040	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EB232_RS21045	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EB232_RS21055	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EB232_RS21065	COG0154	amidase activity
EB232_RS21070	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EB232_RS21080	COG1760	l-serine dehydratase
EB232_RS21090	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EB232_RS21095	COG1686	Belongs to the peptidase S11 family
EB232_RS21105	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EB232_RS21120	COG0537	adenosine 5'-monophosphoramidase activity
EB232_RS21160	COG0052	Belongs to the universal ribosomal protein uS2 family
EB232_RS21165	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EB232_RS21180	COG0667	Aldo Keto reductase
EB232_RS21185	COG0528	UMP kinase activity
EB232_RS21190	COG0233	cytoplasmic translational termination
EB232_RS21195	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EB232_RS21205	COG0750	zinc metalloprotease
EB232_RS21210	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EB232_RS21215	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EB232_RS21220	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EB232_RS21225	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EB232_RS21230	COG3494	Protein of unknown function (DUF1009)
EB232_RS21235	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EB232_RS21240	COG0372	Belongs to the citrate synthase family
EB232_RS21245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EB232_RS21255	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EB232_RS21265	COG3483	tryptophan 2,3-dioxygenase activity
EB232_RS21280	COG0303	'Molybdopterin
EB232_RS21285	COG0315	cyclic pyranopterin monophosphate synthase activity
EB232_RS21290	COG0134	indole-3-glycerol-phosphate synthase activity
EB232_RS21295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EB232_RS21300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EB232_RS21305	COG0149	triose-phosphate isomerase activity
EB232_RS21320	COG0504	CTP synthase activity
EB232_RS21330	COG1953	Uracil, thiamine, allantoin
EB232_RS21335	COG0583	DNA-binding transcription factor activity
EB232_RS21340	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EB232_RS21345	COG2267	carboxylic ester hydrolase activity
EB232_RS21350	COG0747	negative chemotaxis
EB232_RS21355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB232_RS21365	COG0444	Belongs to the ABC transporter superfamily
EB232_RS21370	COG4608	Belongs to the ABC transporter superfamily
EB232_RS21395	COG0010	Belongs to the arginase family
EB232_RS21475	COG3547	Transposase (IS116 IS110 IS902 family)
EB232_RS21485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EB232_RS21500	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EB232_RS21505	COG2202	Pas domain
EB232_RS21505	COG2205	protein histidine kinase activity
EB232_RS21510	COG1525	nuclease
EB232_RS21515	COG0625	glutathione transferase activity
EB232_RS21520	COG1573	uracil-dna glycosylase
EB232_RS21525	COG1522	sequence-specific DNA binding
EB232_RS21545	COG2084	Dehydrogenase
EB232_RS21560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB232_RS21565	COG1763	Mo-molybdopterin cofactor biosynthetic process
EB232_RS21570	COG0746	molybdenum cofactor guanylyltransferase activity
EB232_RS21590	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EB232_RS21605	COG1846	Transcriptional regulator
EB232_RS21650	COG0546	phosphoglycolate phosphatase activity
EB232_RS21655	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EB232_RS21680	COG4178	(ABC) transporter
EB232_RS21700	COG4166	transmembrane transport
EB232_RS21715	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EB232_RS21730	COG1183	phosphatidylcholine synthase activity
EB232_RS21760	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EB232_RS21765	COG0861	Integral membrane protein TerC family
EB232_RS21805	COG0484	heat shock protein binding
EB232_RS21810	COG0582	viral genome integration into host DNA
EB232_RS21965	COG1686	Belongs to the peptidase S11 family
EB232_RS21970	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EB232_RS21990	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EB232_RS21995	COG0084	hydrolase, TatD family'
EB232_RS22000	COG1234	tRNA 3'-trailer cleavage
EB232_RS22025	COG0670	Belongs to the BI1 family
EB232_RS22050	COG3956	TIGRFAM MazG family protein
EB232_RS22055	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EB232_RS22060	COG1923	regulation of RNA biosynthetic process
EB232_RS22065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EB232_RS22070	COG2204	response regulator
EB232_RS22075	COG5000	phosphorelay sensor kinase activity
EB232_RS22080	COG2204	response regulator
EB232_RS22085	COG3852	Histidine kinase
EB232_RS22095	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EB232_RS22095	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EB232_RS22110	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EB232_RS22120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EB232_RS22135	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB232_RS22145	COG0022	dehydrogenase e1 component
EB232_RS22145	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB232_RS22150	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EB232_RS22155	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EB232_RS22160	COG0148	phosphopyruvate hydratase activity
EB232_RS22180	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EB232_RS22195	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EB232_RS22200	COG0737	Belongs to the 5'-nucleotidase family
EB232_RS22205	COG1252	NADH dehydrogenase
EB232_RS22210	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EB232_RS22220	COG1522	sequence-specific DNA binding
EB232_RS22225	COG0686	Belongs to the AlaDH PNT family
EB232_RS22250	COG2897	thiosulfate sulfurtransferase activity
EB232_RS22265	COG0300	oxidoreductase activity
EB232_RS22275	COG0513	Belongs to the DEAD box helicase family
EB232_RS22280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EB232_RS22285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EB232_RS22285	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EB232_RS22290	COG0347	Belongs to the P(II) protein family
EB232_RS22295	COG0174	glutamine synthetase
EB232_RS22315	COG0174	glutamine synthetase
EB232_RS22345	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EB232_RS22355	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS22380	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EB232_RS22390	COG0203	ribosomal protein L17
EB232_RS22395	COG0202	RNA polymerase activity
EB232_RS22400	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EB232_RS22405	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EB232_RS22410	COG0563	adenylate kinase activity
EB232_RS22420	COG0200	Binds to the 23S rRNA
EB232_RS22425	COG1841	ribosomal large subunit assembly
EB232_RS22430	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EB232_RS22435	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EB232_RS22440	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EB232_RS22445	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EB232_RS22450	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EB232_RS22455	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EB232_RS22460	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EB232_RS22465	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EB232_RS22470	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EB232_RS22475	COG0255	Belongs to the universal ribosomal protein uL29 family
EB232_RS22480	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EB232_RS22485	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EB232_RS22490	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EB232_RS22495	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EB232_RS22500	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EB232_RS22505	COG0089	rRNA binding
EB232_RS22510	COG0088	Forms part of the polypeptide exit tunnel
EB232_RS22515	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EB232_RS22520	COG0051	transcription antitermination factor activity, RNA binding
EB232_RS22525	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EB232_RS22530	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EB232_RS22535	COG0049	tRNA binding
EB232_RS22540	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EB232_RS22565	COG4122	O-methyltransferase activity
EB232_RS22570	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EB232_RS22575	COG0085	RNA polymerase activity
EB232_RS22580	COG0222	ribosome binding
EB232_RS22585	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EB232_RS22590	COG0081	regulation of translation
EB232_RS22595	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EB232_RS22605	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EB232_RS22630	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EB232_RS22660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EB232_RS22665	COG2084	Dehydrogenase
EB232_RS22670	COG3622	Belongs to the hyi family
EB232_RS22675	COG3960	tartronate-semialdehyde synthase activity
EB232_RS22680	COG1414	Transcriptional regulator
EB232_RS22745	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EB232_RS22755	COG4208	sulfate ABC transporter
EB232_RS22760	COG3842	ATPase activity
EB232_RS22765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EB232_RS22785	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EB232_RS22790	COG0513	Belongs to the DEAD box helicase family
EB232_RS22800	COG2885	chlorophyll binding
EB232_RS22820	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EB232_RS22825	COG0860	N-Acetylmuramoyl-L-alanine amidase
EB232_RS22830	COG1530	ribonuclease E activity
EB232_RS22835	COG2066	Belongs to the glutaminase family
EB232_RS22840	COG0436	Aminotransferase
EB232_RS22855	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EB232_RS22860	COG0511	ligase activity, forming carbon-carbon bonds
EB232_RS22870	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EB232_RS22895	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EB232_RS22900	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EB232_RS22915	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EB232_RS22920	COG3811	Belongs to the UPF0386 family
EB232_RS22925	COG0517	IMP dehydrogenase activity
EB232_RS22925	COG0516	GMP reductase activity
EB232_RS23010	COG1278	Cold shock
EB232_RS23015	COG0346	lactoylglutathione lyase activity
EB232_RS23030	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EB232_RS23065	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EB232_RS23105	COG2986	histidine ammonia-lyase
EB232_RS23110	COG0494	nUDIX hydrolase
EB232_RS23115	COG1902	pentaerythritol trinitrate reductase activity
EB232_RS23135	COG2267	carboxylic ester hydrolase activity
EB232_RS23140	COG1058	Belongs to the CinA family
EB232_RS23140	COG1546	Belongs to the CinA family
EB232_RS23150	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EB232_RS23165	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EB232_RS23180	COG3547	Transposase (IS116 IS110 IS902 family)
EB232_RS23220	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EB232_RS23230	COG0583	DNA-binding transcription factor activity
EB232_RS23255	COG0586	Pfam SNARE associated Golgi protein
EB232_RS23270	COG1968	undecaprenyl-diphosphatase activity
EB232_RS23300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EB232_RS23305	COG3246	L-lysine catabolic process to acetate
EB232_RS23325	COG0667	Aldo Keto reductase
EB232_RS23355	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EB232_RS23360	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EB232_RS23360	COG3608	succinylglutamate desuccinylase aspartoacylase
EB232_RS23380	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EB232_RS23390	COG3191	aminopeptidase activity
EB232_RS23410	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EB232_RS23415	COG2514	catechol 2,3-dioxygenase activity
EB232_RS23440	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EB232_RS23445	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EB232_RS23455	COG0047	phosphoribosylformylglycinamidine synthase activity
EB232_RS23480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB232_RS23490	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EB232_RS23515	COG0483	inositol monophosphate 1-phosphatase activity
EB232_RS23520	COG0037	tRNA processing
EB232_RS23525	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EB232_RS23550	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EB232_RS23555	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EB232_RS23560	COG0538	isocitrate dehydrogenase activity
EB232_RS23585	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EB232_RS23590	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EB232_RS23600	COG2313	pseudouridylate synthase activity
EB232_RS23610	COG3791	Glutathione-dependent formaldehyde-activating
EB232_RS23615	COG0316	Belongs to the HesB IscA family
EB232_RS23620	COG2151	metal-sulfur cluster biosynthetic enzyme
EB232_RS23625	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EB232_RS23630	COG0719	Fe-S assembly protein
EB232_RS23635	COG0396	ATPase activity
EB232_RS23645	COG0719	Fe-S assembly protein
EB232_RS23655	COG2945	thiolester hydrolase activity
EB232_RS23665	COG0671	phosphoesterase, PA-phosphatase related
EB232_RS23670	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EB232_RS23680	COG0463	Glycosyl transferase, family 2
EB232_RS23685	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EB232_RS23695	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EB232_RS23710	COG0739	heme binding
EB232_RS23715	COG1473	amidohydrolase
EB232_RS23720	COG0006	proline dipeptidase activity
EB232_RS23740	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS23775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB232_RS23785	COG3842	ATPase activity
EB232_RS23795	COG1175	transmembrane transport
EB232_RS23800	COG0395	ABC-type sugar transport system, permease component
EB232_RS23825	COG0776	regulation of translation
EB232_RS23835	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EB232_RS23840	COG0740	serine-type endopeptidase activity
EB232_RS23850	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EB232_RS23850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB232_RS23855	COG2124	cytochrome p450
EB232_RS23875	COG1832	CoA-binding protein
EB232_RS23880	COG1196	nuclear chromosome segregation
EB232_RS23910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EB232_RS23915	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EB232_RS23950	COG0010	Belongs to the arginase family
EB232_RS23955	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EB232_RS23965	COG1612	heme a metabolic process
EB232_RS23990	COG3842	ATPase activity
EB232_RS24005	COG0395	ABC-type sugar transport system, permease component
EB232_RS24030	COG0297	glycogen (starch) synthase activity
EB232_RS24050	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EB232_RS24080	COG0776	regulation of translation
EB232_RS24085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EB232_RS24090	COG0416	fatty acid biosynthetic process
EB232_RS24105	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EB232_RS24115	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EB232_RS24120	COG1174	glycine betaine transport
EB232_RS24125	COG1125	glycine betaine transport
EB232_RS24130	COG1174	glycine betaine transport
EB232_RS24135	COG1732	Glycine betaine
EB232_RS24140	COG2814	Major facilitator Superfamily
EB232_RS24145	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EB232_RS24150	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EB232_RS24160	COG4453	Protein conserved in bacteria
EB232_RS24170	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EB232_RS24170	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EB232_RS24175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EB232_RS24180	COG3136	membrane protein required for alginate biosynthesis
EB232_RS24190	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EB232_RS24195	COG0025	NhaP-type Na H and K H
EB232_RS24200	COG2197	response regulator
EB232_RS24205	COG2989	Protein conserved in bacteria
EB232_RS24220	COG1024	Enoyl-CoA hydratase
EB232_RS24230	COG0113	porphobilinogen synthase activity
EB232_RS24260	COG0667	Aldo Keto reductase
EB232_RS24320	COG0306	phosphate transporter
EB232_RS24325	COG1392	Phosphate transport regulator
EB232_RS24345	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EB232_RS24355	COG0628	permease
EB232_RS24360	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EB232_RS24370	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EB232_RS24380	COG0738	Major facilitator superfamily
EB232_RS24390	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EB232_RS24415	COG0477	Major facilitator Superfamily
EB232_RS24440	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EB232_RS24575	COG0714	Associated with various cellular activities
EB232_RS24605	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EB232_RS24610	COG1132	(ABC) transporter
EB232_RS24615	COG3459	Glycosyltransferase 36 associated
EB232_RS24625	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EB232_RS24640	COG2986	histidine ammonia-lyase
EB232_RS24645	COG1228	amidohydrolase
EB232_RS24650	COG0402	S-adenosylhomocysteine deaminase activity
EB232_RS24655	COG2188	Transcriptional regulator
EB232_RS24660	COG0251	oxidation-reduction process
EB232_RS24670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EB232_RS24675	COG0803	Belongs to the bacterial solute-binding protein 9 family
EB232_RS24715	COG1234	tRNA 3'-trailer cleavage
EB232_RS24720	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EB232_RS24730	COG1063	alcohol dehydrogenase
EB232_RS24735	COG0156	8-amino-7-oxononanoate synthase activity
EB232_RS24745	COG0726	polysaccharide deacetylase
EB232_RS24760	COG1902	pentaerythritol trinitrate reductase activity
EB232_RS24760	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB232_RS24765	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EB232_RS24780	COG0747	negative chemotaxis
EB232_RS24785	COG5598	trimethylamine methyltransferase
EB232_RS24805	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EB232_RS24840	COG1663	tetraacyldisaccharide 4'-kinase activity
EB232_RS24845	COG1519	Transferase
EB232_RS24860	COG0483	inositol monophosphate 1-phosphatase activity
EB232_RS24865	COG0312	modulator of DNA gyrase
EB232_RS24880	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EB232_RS24885	COG2072	flavoprotein involved in K transport
EB232_RS24895	COG2144	transferase activity, transferring acyl groups
EB232_RS24920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB232_RS24930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EB232_RS24935	COG0702	epimerase
EB232_RS24940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EB232_RS24970	COG0612	Peptidase, M16
EB232_RS24975	COG0612	Peptidase, M16
EB232_RS24980	COG0742	ribosomal rna small subunit methyltransferase
EB232_RS24990	COG0590	tRNA wobble adenosine to inosine editing
EB232_RS25000	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EB232_RS25020	COG0196	riboflavin kinase activity
EB232_RS25035	COG1280	lysine exporter protein (LysE YggA)
EB232_RS25050	COG1230	cation diffusion facilitator family transporter
EB232_RS25060	COG2239	Acts as a magnesium transporter
EB232_RS25070	COG2340	Cysteine-rich secretory protein family
EB232_RS25075	COG2814	Major facilitator Superfamily
EB232_RS25080	COG1566	PFAM secretion protein HlyD family protein
EB232_RS25090	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EB232_RS25095	COG2267	carboxylic ester hydrolase activity
EB232_RS25100	COG0671	phosphoesterase, PA-phosphatase related
EB232_RS25100	COG2453	phosphatase
EB232_RS25115	COG4589	Belongs to the CDS family
EB232_RS25120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EB232_RS25130	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EB232_RS25140	COG1609	Transcriptional regulator
EB232_RS25145	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS25150	COG1129	ABC transporter
EB232_RS25160	COG2207	Transcriptional regulator
EB232_RS25160	COG3708	Transcriptional regulator
EB232_RS25165	COG1846	Transcriptional regulator
EB232_RS25165	COG0456	acetyltransferase
EB232_RS25210	COG0459	protein refolding
EB232_RS25230	COG1280	lysine exporter protein (LysE YggA)
EB232_RS25255	COG1278	Cold shock
EB232_RS25270	COG3237	CsbD-like
EB232_RS25290	COG1309	transcriptional regulator
EB232_RS25305	COG0114	fumarate hydratase activity
EB232_RS25310	COG2259	Doxx family
EB232_RS25325	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EB232_RS25335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EB232_RS25350	COG1126	abc transporter atp-binding protein
EB232_RS25355	COG0765	amino acid transport
EB232_RS25360	COG4597	amino acid ABC transporter
EB232_RS25365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB232_RS25380	COG0626	cystathionine gamma-synthase activity
EB232_RS25390	COG1024	Enoyl-CoA hydratase
EB232_RS25415	COG0438	transferase activity, transferring glycosyl groups
EB232_RS25420	COG5002	protein histidine kinase activity
EB232_RS25420	COG3447	MASE1 domain protein
EB232_RS25420	COG5001	Diguanylate cyclase
EB232_RS25455	COG0628	permease
EB232_RS25465	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EB232_RS25470	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EB232_RS25495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB232_RS25510	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EB232_RS25530	COG1473	amidohydrolase
EB232_RS25540	COG1522	sequence-specific DNA binding
EB232_RS25545	COG2072	flavoprotein involved in K transport
EB232_RS25555	COG0243	molybdopterin cofactor binding
EB232_RS25560	COG0488	(ABC) transporter
EB232_RS25565	COG4957	zinc ion binding
EB232_RS25605	COG0105	UTP biosynthetic process
EB232_RS25610	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EB232_RS25615	COG0314	molybdopterin synthase activity
EB232_RS25625	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EB232_RS25630	COG0322	excinuclease ABC activity
EB232_RS25645	COG0625	glutathione transferase activity
EB232_RS25660	COG1280	lysine exporter protein (LysE YggA)
EB232_RS25680	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EB232_RS25705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EB232_RS25750	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EB232_RS25775	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EB232_RS25780	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EB232_RS25785	COG0194	GDP metabolic process
EB232_RS25790	COG1561	YicC-like family, N-terminal region
EB232_RS25795	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EB232_RS25800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EB232_RS25805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EB232_RS25815	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EB232_RS25820	COG1368	sulfuric ester hydrolase activity
EB232_RS25830	COG0360	Binds together with S18 to 16S ribosomal RNA
EB232_RS25835	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EB232_RS25840	COG0359	binds to the 23S rRNA
EB232_RS25845	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EB232_RS25850	COG1742	UPF0060 membrane protein
EB232_RS25875	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EB232_RS25880	COG4221	oxidoreductase activity
EB232_RS25895	COG0697	spore germination
EB232_RS25905	COG0583	DNA-binding transcription factor activity
EB232_RS25915	COG0318	PFAM AMP-dependent synthetase and ligase
EB232_RS25915	COG0204	Acyl-transferase
EB232_RS25920	COG1183	phosphatidylcholine synthase activity
EB232_RS25925	COG0688	phosphatidylethanolamine metabolic process
EB232_RS25940	COG3386	PFAM SMP-30 Gluconolaconase
EB232_RS25950	COG5265	(ABC) transporter
EB232_RS25955	COG0640	Transcriptional regulator
EB232_RS25960	COG0583	DNA-binding transcription factor activity
EB232_RS25970	COG1652	LysM domain
EB232_RS25980	COG0583	DNA-binding transcription factor activity
EB232_RS26000	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EB232_RS26025	COG0215	cysteine-tRNA ligase activity
EB232_RS26065	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EB232_RS26070	COG0354	folic acid binding
EB232_RS26075	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EB232_RS26080	COG5001	Diguanylate cyclase
EB232_RS26090	COG0583	DNA-binding transcription factor activity
EB232_RS26115	COG1595	DNA-templated transcription, initiation
EB232_RS26125	COG1381	Involved in DNA repair and RecF pathway recombination
EB232_RS26140	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EB232_RS26145	COG0571	ribonuclease III activity
EB232_RS26150	COG0681	Belongs to the peptidase S26 family
EB232_RS26155	COG0736	holo-[acyl-carrier-protein] synthase activity
EB232_RS26170	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EB232_RS26180	COG1758	RNA polymerase activity
EB232_RS26200	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EB232_RS26205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EB232_RS26210	COG0741	lytic transglycosylase activity
EB232_RS26240	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EB232_RS26245	COG0456	acetyltransferase
EB232_RS26245	COG1846	Transcriptional regulator
EB232_RS26250	COG1254	Belongs to the acylphosphatase family
EB232_RS26260	COG1960	acyl-CoA dehydrogenase activity
EB232_RS26270	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EB232_RS26315	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EB232_RS26340	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EB232_RS26400	COG0308	aminopeptidase N
EB232_RS26405	COG2202	Pas domain
EB232_RS26405	COG2205	protein histidine kinase activity
EB232_RS26415	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EB232_RS26425	COG0745	RESPONSE REGULATOR receiver
EB232_RS26430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EB232_RS26435	COG3088	subunit of a heme lyase
EB232_RS26440	COG1138	Cytochrome C-type biogenesis protein
EB232_RS26445	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EB232_RS26450	COG4235	cytochrome complex assembly
EB232_RS26460	COG5002	protein histidine kinase activity
EB232_RS26465	COG0745	RESPONSE REGULATOR receiver
EB232_RS26480	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS26510	COG3842	ATPase activity
EB232_RS26545	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS26560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB232_RS26575	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EB232_RS26605	COG3757	hydrolase, family 25
EB232_RS26605	COG3409	Peptidoglycan-binding domain 1 protein
EB232_RS26610	COG2205	protein histidine kinase activity
EB232_RS26620	COG2166	iron-sulfur cluster assembly
EB232_RS26640	COG1280	lysine exporter protein (LysE YggA)
EB232_RS26650	COG2010	Cytochrome c
EB232_RS26655	COG3909	cytochrome
EB232_RS26660	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EB232_RS26665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EB232_RS26680	COG0433	COG0433 Predicted ATPase
EB232_RS26700	COG3654	unkown
EB232_RS26720	COG0183	Belongs to the thiolase family
EB232_RS26725	COG1309	transcriptional regulator
EB232_RS26730	COG3119	arylsulfatase activity
EB232_RS26740	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EB232_RS26745	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS26795	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EB232_RS26825	COG2010	Cytochrome c
EB232_RS26850	COG0517	IMP dehydrogenase activity
EB232_RS26855	COG3794	PFAM blue (type 1) copper domain protein
EB232_RS26860	COG3976	FMN-binding domain protein
EB232_RS26860	COG1053	succinate dehydrogenase
EB232_RS26880	COG0745	RESPONSE REGULATOR receiver
EB232_RS26920	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EB232_RS26930	COG4191	Histidine kinase
EB232_RS26940	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB232_RS26940	COG0022	dehydrogenase e1 component
EB232_RS27000	COG0045	succinate-CoA ligase (ADP-forming) activity
EB232_RS27000	COG1042	CoA-binding domain protein
EB232_RS27000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EB232_RS27005	COG2217	Heavy metal translocating P-type atpase
EB232_RS27010	COG3118	belongs to the thioredoxin family
EB232_RS27055	COG2235	arginine
EB232_RS27060	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EB232_RS27070	COG2815	serine threonine protein kinase
EB232_RS27070	COG0515	serine threonine protein kinase
EB232_RS27125	COG4172	Belongs to the ABC transporter superfamily
EB232_RS27130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB232_RS27135	COG0601	transmembrane transport
EB232_RS27140	COG4166	transmembrane transport
EB232_RS27155	COG0366	Alpha amylase catalytic
EB232_RS27160	COG1523	belongs to the glycosyl hydrolase 13 family
EB232_RS27165	COG0033	Phosphoglucomutase
EB232_RS27170	COG0297	glycogen (starch) synthase activity
EB232_RS27175	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EB232_RS27180	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EB232_RS27185	COG0058	SHG alpha-glucan phosphorylase activity
EB232_RS27225	COG1218	3'(2'),5'-bisphosphate nucleotidase
EB232_RS27235	COG0175	sulfate reduction
EB232_RS27240	COG3307	-O-antigen
EB232_RS27250	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EB232_RS27265	COG0438	transferase activity, transferring glycosyl groups
EB232_RS27300	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EB232_RS27305	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EB232_RS27315	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EB232_RS27320	COG1091	dTDP-4-dehydrorhamnose reductase activity
EB232_RS27325	COG1088	dTDP-glucose 4,6-dehydratase activity
EB232_RS27330	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
EB232_RS27345	COG1268	BioY protein
EB232_RS27360	COG1177	transmembrane transport
EB232_RS27365	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB232_RS27370	COG3842	ATPase activity
EB232_RS27380	COG1609	Transcriptional regulator
EB232_RS27415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EB232_RS27415	COG0574	Belongs to the PEP-utilizing enzyme family
EB232_RS27450	COG1396	sequence-specific DNA binding
EB232_RS27465	COG1196	nuclear chromosome segregation
EB232_RS27470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EB232_RS27480	COG1194	a g-specific adenine glycosylase
EB232_RS27490	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EB232_RS27495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EB232_RS27510	COG0612	Peptidase, M16
EB232_RS27515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EB232_RS27525	COG1678	Uncharacterized ACR, COG1678
EB232_RS27535	COG0678	peroxiredoxin activity
EB232_RS27550	COG0328	RNA-DNA hybrid ribonuclease activity
EB232_RS27555	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EB232_RS27560	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EB232_RS27565	COG3346	SURF1 family
EB232_RS27580	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EB232_RS27590	COG0109	protoheme IX farnesyltransferase activity
EB232_RS27595	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EB232_RS27600	COG1565	acr, cog1565
EB232_RS27600	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EB232_RS27615	COG0312	modulator of DNA gyrase
EB232_RS27630	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EB232_RS27650	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EB232_RS27655	COG1741	Belongs to the pirin family
EB232_RS27665	COG1722	exodeoxyribonuclease VII activity
EB232_RS27670	COG0123	including yeast histone deacetylase and acetoin utilization protein
EB232_RS27675	COG0778	Nitroreductase
EB232_RS27685	COG1309	transcriptional regulator
EB232_RS27695	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EB232_RS27695	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EB232_RS27700	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EB232_RS27710	COG0406	alpha-ribazole phosphatase activity
EB232_RS27715	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EB232_RS27720	COG0484	heat shock protein binding
EB232_RS27730	COG0259	pyridoxamine-phosphate oxidase activity
EB232_RS27735	COG1024	Enoyl-CoA hydratase
EB232_RS27740	COG1960	acyl-CoA dehydrogenase activity
EB232_RS27760	COG0151	Belongs to the GarS family
EB232_RS27770	COG0583	DNA-binding transcription factor activity
EB232_RS27775	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EB232_RS27790	COG0277	FAD linked oxidase domain protein
EB232_RS27795	COG0009	L-threonylcarbamoyladenylate synthase
EB232_RS27815	COG0751	glycine-tRNA ligase activity
EB232_RS27825	COG0752	glycyl-tRNA synthetase alpha subunit
EB232_RS27855	COG0142	geranyltranstransferase activity
EB232_RS27880	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EB232_RS27885	COG0521	Mo-molybdopterin cofactor biosynthetic process
EB232_RS27905	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EB232_RS27910	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EB232_RS27915	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EB232_RS27925	COG0356	it plays a direct role in the translocation of protons across the membrane
EB232_RS27945	COG0583	DNA-binding transcription factor activity
EB232_RS27950	COG1160	GTP binding
EB232_RS27955	COG2976	Protein conserved in bacteria
EB232_RS27965	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EB232_RS27970	COG0477	Major facilitator Superfamily
EB232_RS27980	COG0583	DNA-binding transcription factor activity
EB232_RS27985	COG2309	aminopeptidase activity
EB232_RS27990	COG3189	MarR family transcriptional regulator
EB232_RS27995	COG1393	Belongs to the ArsC family
EB232_RS28005	COG3842	ATPase activity
EB232_RS28020	COG1177	transmembrane transport
EB232_RS28025	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB232_RS28040	COG4948	Mandelate Racemase Muconate Lactonizing
EB232_RS28065	COG2017	converts alpha-aldose to the beta-anomer
EB232_RS28075	COG1129	ABC transporter
EB232_RS28080	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS28090	COG1309	transcriptional regulator
EB232_RS28105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB232_RS28110	COG0583	DNA-binding transcription factor activity
EB232_RS28125	COG4948	Mandelate Racemase Muconate Lactonizing
EB232_RS28135	COG0747	negative chemotaxis
EB232_RS28140	COG0601	transmembrane transport
EB232_RS28145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB232_RS28155	COG0583	DNA-binding transcription factor activity
EB232_RS28160	COG0747	negative chemotaxis
EB232_RS28175	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS28185	COG2113	Glycine betaine
EB232_RS28190	COG0517	IMP dehydrogenase activity
EB232_RS28190	COG4175	Glycine betaine
EB232_RS28195	COG4176	ABC-type proline glycine betaine transport system permease component
EB232_RS28230	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB232_RS28250	COG0531	amino acid
EB232_RS28265	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EB232_RS28270	COG2218	PFAM glutamate synthase alpha subunit domain protein
EB232_RS28275	COG0069	glutamate synthase activity
EB232_RS28285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB232_RS28290	COG4311	Sarcosine oxidase, delta subunit
EB232_RS28295	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB232_RS28295	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB232_RS28305	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB232_RS28335	COG0318	PFAM AMP-dependent synthetase and ligase
EB232_RS28345	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS28345	COG3347	Dehydrogenase
EB232_RS28360	COG1129	ABC transporter
EB232_RS28365	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EB232_RS28370	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EB232_RS28375	COG1522	sequence-specific DNA binding
EB232_RS28385	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EB232_RS28390	COG2376	Dihydroxyacetone kinase
EB232_RS28400	COG0698	ribose 5-phosphate isomerase
EB232_RS28405	COG0149	triose-phosphate isomerase activity
EB232_RS28445	COG3842	ATPase activity
EB232_RS28460	COG1175	transmembrane transport
EB232_RS28465	COG1653	transport
EB232_RS28475	COG3552	Protein containing von Willebrand factor type A (VWA) domain
EB232_RS28485	COG0714	Associated with various cellular activities
EB232_RS28500	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EB232_RS28510	COG0174	glutamine synthetase
EB232_RS28525	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EB232_RS28535	COG2204	response regulator
EB232_RS28540	COG4191	Histidine kinase
EB232_RS28545	COG1301	dicarboxylic acid transport
EB232_RS28550	COG1940	carbohydrate kinase activity
EB232_RS28570	COG0673	inositol 2-dehydrogenase activity
EB232_RS28580	COG0395	ABC-type sugar transport system, permease component
EB232_RS28585	COG1175	transmembrane transport
EB232_RS28600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB232_RS28610	COG1349	DNA-binding transcription factor activity
EB232_RS28615	COG0673	inositol 2-dehydrogenase activity
EB232_RS28640	COG3485	protocatechuate 3,4-dioxygenase
EB232_RS28645	COG3485	protocatechuate 3,4-dioxygenase
EB232_RS28650	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EB232_RS28655	COG2267	carboxylic ester hydrolase activity
EB232_RS28660	COG0583	DNA-binding transcription factor activity
EB232_RS28695	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS28730	COG3842	ATPase activity
EB232_RS28740	COG1177	transmembrane transport
EB232_RS28745	COG0277	FAD linked oxidase domain protein
EB232_RS28760	COG0667	Aldo Keto reductase
EB232_RS28790	COG0559	Belongs to the binding-protein-dependent transport system permease family
EB232_RS28800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB232_RS28805	COG1802	Transcriptional regulator
EB232_RS28810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EB232_RS28820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB232_RS28870	COG3618	amidohydrolase
EB232_RS28885	COG1175	transmembrane transport
EB232_RS28890	COG0395	ABC-type sugar transport system, permease component
EB232_RS28895	COG3842	ATPase activity
EB232_RS28900	COG4948	Mandelate Racemase Muconate Lactonizing
EB232_RS28940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EB232_RS28950	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS28960	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EB232_RS28980	COG1349	DNA-binding transcription factor activity
EB232_RS28995	COG2986	histidine ammonia-lyase
EB232_RS29000	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EB232_RS29005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB232_RS29010	COG1132	(ABC) transporter
EB232_RS29015	COG1132	(ABC) transporter
EB232_RS29065	COG1063	alcohol dehydrogenase
EB232_RS29070	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EB232_RS29075	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS29080	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EB232_RS29085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB232_RS29090	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS29100	COG1335	isochorismatase
EB232_RS29125	COG1744	ABC transporter substrate-binding protein PnrA-like
EB232_RS29155	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EB232_RS29170	COG0583	DNA-binding transcription factor activity
EB232_RS29175	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS29185	COG0251	oxidation-reduction process
EB232_RS29190	COG2072	flavoprotein involved in K transport
EB232_RS29205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB232_RS29270	COG2885	chlorophyll binding
EB232_RS29315	COG0129	dihydroxy-acid dehydratase activity
EB232_RS29320	COG3501	Rhs element vgr protein
EB232_RS29355	COG0739	heme binding
EB232_RS29390	COG0456	acetyltransferase
EB232_RS29395	COG1177	transmembrane transport
EB232_RS29405	COG3842	ATPase activity
EB232_RS29415	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS29420	COG4948	Mandelate Racemase Muconate Lactonizing
EB232_RS29460	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EB232_RS29470	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EB232_RS29495	COG5265	(ABC) transporter
EB232_RS29500	COG4988	ABC transporter
EB232_RS29505	COG1271	oxidase subunit
EB232_RS29510	COG1294	oxidase, subunit
EB232_RS29525	COG0583	DNA-binding transcription factor activity
EB232_RS29535	COG0583	DNA-binding transcription factor activity
EB232_RS29545	COG1064	alcohol dehydrogenase
EB232_RS29560	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
EB232_RS29570	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EB232_RS29585	COG4948	Mandelate Racemase Muconate Lactonizing
EB232_RS29595	COG4948	Mandelate Racemase Muconate Lactonizing
EB232_RS29600	COG4948	Mandelate Racemase Muconate Lactonizing
EB232_RS29610	COG1653	transport
EB232_RS29625	COG3842	ATPase activity
EB232_RS29630	COG4948	Mandelate Racemase Muconate Lactonizing
EB232_RS29645	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EB232_RS29650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EB232_RS29655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB232_RS29660	COG1116	anion transmembrane transporter activity
EB232_RS29665	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EB232_RS29675	COG0243	molybdopterin cofactor binding
EB232_RS29685	COG0395	ABC-type sugar transport system, permease component
EB232_RS29690	COG1175	transmembrane transport
EB232_RS29700	COG1802	Transcriptional regulator
EB232_RS29840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EB232_RS29860	COG2197	response regulator
EB232_RS29865	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EB232_RS29870	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EB232_RS29875	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EB232_RS29885	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
EB232_RS29890	COG4310	Domain of unknown function (DUF2172)
EB232_RS29895	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EB232_RS29930	COG0438	transferase activity, transferring glycosyl groups
EB232_RS29940	COG0297	glycogen (starch) synthase activity
EB232_RS29950	COG1596	polysaccharide export
EB232_RS30005	COG0583	DNA-binding transcription factor activity
EB232_RS30015	COG4221	oxidoreductase activity
EB232_RS30020	COG0406	alpha-ribazole phosphatase activity
EB232_RS30025	COG0668	transmembrane transport
EB232_RS30060	COG1247	-acetyltransferase
EB232_RS30080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB232_RS30085	COG0601	transmembrane transport
EB232_RS30125	COG1234	tRNA 3'-trailer cleavage
EB232_RS30135	COG1132	(ABC) transporter
EB232_RS30135	COG1132	(ABC) transporter
EB232_RS30145	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EB232_RS30175	COG0457	Tetratricopeptide repeat
EB232_RS30195	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EB232_RS30205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EB232_RS30245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EB232_RS30255	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS30260	COG0473	3-isopropylmalate dehydrogenase activity
EB232_RS30265	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS30270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB232_RS30285	COG0454	-acetyltransferase
EB232_RS30310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB232_RS30320	COG1522	sequence-specific DNA binding
EB232_RS30340	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
EB232_RS30350	COG0583	DNA-binding transcription factor activity
EB232_RS30355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB232_RS30385	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EB232_RS30395	COG1793	dna ligase
EB232_RS30420	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS30430	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EB232_RS30495	COG4948	Mandelate Racemase Muconate Lactonizing
EB232_RS30500	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS30525	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EB232_RS30535	COG2353	YceI-like domain
EB232_RS30545	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS30560	COG5441	Belongs to the UPF0261 family
EB232_RS30570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EB232_RS30585	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EB232_RS30590	COG1846	Transcriptional regulator
EB232_RS30605	COG3384	dioxygenase
EB232_RS30615	COG0179	Fumarylacetoacetate (FAA) hydrolase
EB232_RS30620	COG3971	2-oxopent-4-enoate hydratase activity
EB232_RS30645	COG2207	Transcriptional regulator
EB232_RS30690	COG0583	DNA-binding transcription factor activity
EB232_RS30715	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EB232_RS30720	COG0745	RESPONSE REGULATOR receiver
EB232_RS30740	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EB232_RS30755	COG0583	DNA-binding transcription factor activity
EB232_RS30785	COG1396	sequence-specific DNA binding
EB232_RS30800	COG1335	isochorismatase
EB232_RS30805	COG1741	Belongs to the pirin family
EB232_RS30810	COG0583	DNA-binding transcription factor activity
EB232_RS30855	COG0583	DNA-binding transcription factor activity
EB232_RS30885	COG3335	DDE superfamily endonuclease
EB232_RS30890	COG3415	Transposase
EB232_RS30925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB232_RS30945	COG1725	Transcriptional regulator
EB232_RS30950	COG0747	negative chemotaxis
EB232_RS30955	COG0601	transmembrane transport
EB232_RS30965	COG0444	Belongs to the ABC transporter superfamily
EB232_RS30975	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EB232_RS30980	COG1063	alcohol dehydrogenase
EB232_RS30985	COG1879	ABC-type sugar transport system periplasmic component
EB232_RS30995	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS31000	COG1802	Transcriptional regulator
EB232_RS31020	COG3293	Transposase
EB232_RS31035	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EB232_RS31055	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EB232_RS31065	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS31105	COG3436	PFAM IS66 Orf2 family protein
EB232_RS31110	COG4372	Transposase
EB232_RS31125	COG1802	Transcriptional regulator
EB232_RS31135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EB232_RS31155	COG2721	sulfolactate sulfo-lyase activity
EB232_RS31170	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS31175	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EB232_RS31185	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EB232_RS31235	COG1309	transcriptional regulator
EB232_RS31255	COG0596	Alpha beta hydrolase
EB232_RS31270	COG4957	zinc ion binding
EB232_RS31280	COG2948	multi-organism process
EB232_RS31290	COG3701	Conjugal transfer protein
EB232_RS31295	COG3846	protein secretion by the type IV secretion system
EB232_RS31310	COG3451	type IV secretory pathway VirB4
EB232_RS31320	COG3838	Conjugal transfer protein Trbc
EB232_RS31325	COG4962	Type ii secretion system protein e
EB232_RS31335	COG3550	peptidyl-serine autophosphorylation
EB232_RS31360	COG0741	lytic transglycosylase activity
EB232_RS31400	COG5489	Protein of unknown function (DUF736)
EB232_RS31430	COG4227	nucleotidyltransferase activity
EB232_RS31465	COG0671	phosphoesterase, PA-phosphatase related
EB232_RS31470	COG1597	lipid kinase activity
EB232_RS31475	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EB232_RS31485	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EB232_RS31495	COG1295	ribonuclease BN
EB232_RS31565	COG3608	succinylglutamate desuccinylase aspartoacylase
EB232_RS31570	COG0006	proline dipeptidase activity
EB232_RS31575	COG2423	ornithine cyclodeaminase activity
EB232_RS31580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EB232_RS31590	COG0765	amino acid transport
EB232_RS31595	COG0765	amino acid transport
EB232_RS31600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB232_RS31605	COG1126	abc transporter atp-binding protein
EB232_RS31610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB232_RS31615	COG1522	sequence-specific DNA binding
EB232_RS31620	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS31625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EB232_RS31675	COG0110	maltose O-acetyltransferase activity
EB232_RS31770	COG0625	glutathione transferase activity
EB232_RS31785	COG1741	Belongs to the pirin family
EB232_RS31815	COG4566	intracellular signal transduction
EB232_RS31820	COG4191	Histidine kinase
EB232_RS31825	COG0601	transmembrane transport
EB232_RS31830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB232_RS31840	COG0747	negative chemotaxis
EB232_RS31860	COG4566	intracellular signal transduction
EB232_RS31865	COG2204	response regulator
EB232_RS31870	COG4566	intracellular signal transduction
EB232_RS31875	COG4191	Histidine kinase
EB232_RS31900	COG0517	IMP dehydrogenase activity
EB232_RS31900	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EB232_RS31935	COG3550	peptidyl-serine autophosphorylation
EB232_RS31985	COG3177	Filamentation induced by cAMP protein fic
EB232_RS31995	COG0519	Catalyzes the synthesis of GMP from XMP
EB232_RS31995	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EB232_RS32020	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EB232_RS32025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EB232_RS32025	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EB232_RS32030	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EB232_RS32035	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EB232_RS32040	COG0583	DNA-binding transcription factor activity
EB232_RS32055	COG0387	Pfam Sodium calcium exchanger
EB232_RS32060	COG0318	PFAM AMP-dependent synthetase and ligase
EB232_RS32065	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EB232_RS32070	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EB232_RS32075	COG0124	histidyl-tRNA synthetase
EB232_RS32090	COG2818	Glycosylase
EB232_RS32095	COG1376	ErfK ybiS ycfS ynhG family protein
EB232_RS32100	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EB232_RS32105	COG0247	lactate metabolic process
EB232_RS32110	COG0277	FAD linked oxidase domain protein
EB232_RS32115	COG0277	FAD linked oxidase domain protein
EB232_RS32130	COG1304	FMN binding
EB232_RS32170	COG0583	DNA-binding transcription factor activity
EB232_RS32180	COG1570	exodeoxyribonuclease VII activity
EB232_RS32215	COG1312	Catalyzes the dehydration of D-mannonate
EB232_RS32220	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS32240	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EB232_RS32255	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EB232_RS32260	COG1845	cytochrome c oxidase, subunit III
EB232_RS32265	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EB232_RS32270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EB232_RS32275	COG0477	Major facilitator Superfamily
EB232_RS32280	COG2130	NADP-dependent
EB232_RS32295	COG3938	Belongs to the proline racemase family
EB232_RS32300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EB232_RS32305	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS32310	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EB232_RS32315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EB232_RS32330	COG1129	ABC transporter
EB232_RS32350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB232_RS32355	COG1116	anion transmembrane transporter activity
EB232_RS32360	COG1250	3-hydroxyacyl-CoA dehydrogenase
EB232_RS32370	COG0235	Class ii aldolase
EB232_RS32390	COG2945	thiolester hydrolase activity
EB232_RS32390	COG0596	Alpha beta hydrolase
EB232_RS32395	COG2188	Transcriptional regulator
EB232_RS32420	COG5490	Phasin protein
EB232_RS32425	COG2205	protein histidine kinase activity
EB232_RS32430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EB232_RS32445	COG1177	transmembrane transport
EB232_RS32450	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB232_RS32455	COG3842	ATPase activity
EB232_RS32475	COG2224	Isocitrate lyase
EB232_RS32495	COG0174	glutamine synthetase
EB232_RS32500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB232_RS32510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EB232_RS32520	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EB232_RS32525	COG0363	glucosamine-6-phosphate deaminase activity
EB232_RS32530	COG0129	dihydroxy-acid dehydratase activity
EB232_RS32535	COG2304	oxidoreductase activity
EB232_RS32545	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EB232_RS32560	COG1396	sequence-specific DNA binding
EB232_RS32575	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EB232_RS32605	COG2132	Multicopper oxidase
EB232_RS32690	COG4964	Belongs to the GSP D family
EB232_RS32740	COG2274	protein secretion by the type I secretion system
EB232_RS32785	COG3706	GGDEF domain
EB232_RS32890	COG3436	PFAM IS66 Orf2 family protein
EB232_RS32895	COG4372	Transposase
EB232_RS32935	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EB232_RS32945	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EB232_RS32950	COG5328	Belongs to the UPF0262 family
EB232_RS32960	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EB232_RS32965	COG0424	maF-like protein
EB232_RS32970	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EB232_RS32975	COG1486	melibiose metabolic process
EB232_RS32980	COG4172	Belongs to the ABC transporter superfamily
EB232_RS32985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB232_RS32990	COG0601	transmembrane transport
EB232_RS32995	COG0747	negative chemotaxis
EB232_RS33000	COG1486	melibiose metabolic process
EB232_RS33005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EB232_RS33005	COG2207	Transcriptional regulator
EB232_RS33035	COG2207	Transcriptional regulator
EB232_RS33045	COG0582	viral genome integration into host DNA
EB232_RS33090	COG4952	isomerase
EB232_RS33095	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS33095	COG3347	Dehydrogenase
EB232_RS33100	COG1349	DNA-binding transcription factor activity
EB232_RS33110	COG1129	ABC transporter
EB232_RS33115	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS33120	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB232_RS33125	COG3254	rhamnose metabolic process
EB232_RS33130	COG1070	Carbohydrate kinase
EB232_RS33135	COG3457	Alanine racemase
EB232_RS33140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB232_RS33150	COG0156	8-amino-7-oxononanoate synthase activity
EB232_RS33155	COG0436	Aminotransferase
EB232_RS33160	COG1970	mechanosensitive ion channel activity
EB232_RS33165	COG2205	protein histidine kinase activity
EB232_RS33165	COG2198	Histidine kinase
EB232_RS33165	COG0784	Response regulator, receiver
EB232_RS33185	COG0167	dihydroorotate dehydrogenase activity
EB232_RS33190	COG0534	Mate efflux family protein
EB232_RS33195	COG0123	including yeast histone deacetylase and acetoin utilization protein
EB232_RS33225	COG0745	RESPONSE REGULATOR receiver
EB232_RS33230	COG0642	Histidine kinase
EB232_RS33235	COG0463	Glycosyl transferase, family 2
EB232_RS33250	COG2755	lipolytic protein G-D-S-L family
EB232_RS33250	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EB232_RS33280	COG1129	ABC transporter
EB232_RS33285	COG4214	carbohydrate transport
EB232_RS33295	COG0717	Belongs to the dCTP deaminase family
EB232_RS33310	COG2967	ApaG domain
EB232_RS33320	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EB232_RS33325	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EB232_RS33335	COG0598	Magnesium transport protein CorA
EB232_RS33340	COG0704	Plays a role in the regulation of phosphate uptake
EB232_RS33345	COG5002	protein histidine kinase activity
EB232_RS33350	COG2326	polyphosphate kinase activity
EB232_RS33355	COG1024	Enoyl-CoA hydratase
EB232_RS33365	COG2197	response regulator
EB232_RS33370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB232_RS33380	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EB232_RS33400	COG1024	Enoyl-CoA hydratase
EB232_RS33400	COG1250	3-hydroxyacyl-CoA dehydrogenase
EB232_RS33405	COG0183	Belongs to the thiolase family
EB232_RS33410	COG1960	acyl-CoA dehydrogenase activity
EB232_RS33415	COG1960	acyl-CoA dehydrogenase activity
EB232_RS33420	COG0789	Transcriptional regulator
EB232_RS33430	COG0730	response to heat
EB232_RS33440	COG0443	Heat shock 70 kDa protein
EB232_RS33450	COG0243	molybdopterin cofactor binding
EB232_RS33455	COG0437	4 iron, 4 sulfur cluster binding
EB232_RS33460	COG3302	dmso reductase anchor subunit
EB232_RS33470	COG1201	RNA secondary structure unwinding
EB232_RS33475	COG0791	NLP P60 protein
EB232_RS33485	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EB232_RS33520	COG4964	Belongs to the GSP D family
EB232_RS33560	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EB232_RS33565	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EB232_RS33570	COG1024	Enoyl-CoA hydratase
EB232_RS33575	COG0268	Binds directly to 16S ribosomal RNA
EB232_RS33580	COG1192	Involved in chromosome partitioning
EB232_RS33585	COG1475	DNA binding
EB232_RS33590	COG1414	Transcriptional regulator
EB232_RS33600	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EB232_RS33680	COG4245	von Willebrand factor, type A
EB232_RS33690	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
EB232_RS33700	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EB232_RS33740	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
EB232_RS33745	COG1126	abc transporter atp-binding protein
EB232_RS33750	COG0765	amino acid transport
EB232_RS33755	COG0765	amino acid transport
EB232_RS33770	COG0154	amidase activity
EB232_RS33775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB232_RS33785	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB232_RS33785	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB232_RS33810	COG1104	cysteine desulfurase activity
EB232_RS33825	COG5490	Phasin protein
EB232_RS33845	COG4227	nucleotidyltransferase activity
EB232_RS33865	COG4974	Belongs to the 'phage' integrase family
EB232_RS33905	COG2963	transposase activity
EB232_RS33930	COG4974	Belongs to the 'phage' integrase family
EB232_RS33935	COG0582	viral genome integration into host DNA
EB232_RS33940	COG4974	Belongs to the 'phage' integrase family
EB232_RS33950	COG4974	Belongs to the 'phage' integrase family
EB232_RS33955	COG0517	IMP dehydrogenase activity
EB232_RS33995	COG3831	ATPase activity
EB232_RS34005	COG0489	protein tyrosine kinase activity
EB232_RS34005	COG2151	metal-sulfur cluster biosynthetic enzyme
EB232_RS34035	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
EB232_RS34040	COG2948	multi-organism process
EB232_RS34055	COG3704	protein secretion by the type IV secretion system
EB232_RS34070	COG3451	type IV secretory pathway VirB4
EB232_RS34085	COG1196	nuclear chromosome segregation
EB232_RS34085	COG0739	heme binding
EB232_RS34085	COG0741	lytic transglycosylase activity
EB232_RS34185	COG4957	zinc ion binding
EB232_RS34190	COG1278	Cold shock
EB232_RS34200	COG5490	Phasin protein
EB232_RS34215	COG5001	Diguanylate cyclase
EB232_RS34215	COG3300	MHYT domain
EB232_RS34240	COG1487	ribonuclease activity
EB232_RS34245	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EB232_RS34250	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EB232_RS34260	COG1278	Cold shock
EB232_RS34265	COG3706	GGDEF domain
EB232_RS34270	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS34275	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EB232_RS34290	COG2022	thiamine diphosphate biosynthetic process
EB232_RS34310	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EB232_RS34315	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EB232_RS34345	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EB232_RS34350	COG1522	sequence-specific DNA binding
EB232_RS34365	COG1396	sequence-specific DNA binding
EB232_RS34365	COG3800	Transcriptional regulator
EB232_RS34370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EB232_RS34375	COG4770	biotin carboxylase activity
EB232_RS34380	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EB232_RS34380	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EB232_RS34385	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EB232_RS34390	COG0156	8-amino-7-oxononanoate synthase activity
EB232_RS34405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EB232_RS34410	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EB232_RS34415	COG2814	Major facilitator Superfamily
EB232_RS34475	COG4166	transmembrane transport
EB232_RS34490	COG4948	Mandelate Racemase Muconate Lactonizing
EB232_RS34515	COG0156	8-amino-7-oxononanoate synthase activity
EB232_RS34530	COG1473	amidohydrolase
EB232_RS34550	COG0517	IMP dehydrogenase activity
EB232_RS34555	COG4974	Belongs to the 'phage' integrase family
EB232_RS34560	COG4974	Belongs to the 'phage' integrase family
EB232_RS34565	COG0582	viral genome integration into host DNA
EB232_RS34595	COG1522	sequence-specific DNA binding
EB232_RS34600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EB232_RS34635	COG2843	Capsule synthesis protein
EB232_RS34640	COG4608	Belongs to the ABC transporter superfamily
EB232_RS34645	COG0444	Belongs to the ABC transporter superfamily
EB232_RS34650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB232_RS34655	COG0601	transmembrane transport
EB232_RS34660	COG0747	negative chemotaxis
EB232_RS34670	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EB232_RS34675	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS34680	COG1522	sequence-specific DNA binding
EB232_RS34685	COG4175	Glycine betaine
EB232_RS34685	COG3448	diguanylate cyclase activity
EB232_RS34690	COG4176	ABC-type proline glycine betaine transport system permease component
EB232_RS34700	COG0006	proline dipeptidase activity
EB232_RS34705	COG1522	sequence-specific DNA binding
EB232_RS34720	COG1473	amidohydrolase
EB232_RS34725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EB232_RS34730	COG2423	ornithine cyclodeaminase activity
EB232_RS34745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB232_RS34750	COG3608	succinylglutamate desuccinylase aspartoacylase
EB232_RS34760	COG0006	proline dipeptidase activity
EB232_RS34775	COG0765	amino acid transport
EB232_RS34780	COG1126	abc transporter atp-binding protein
EB232_RS34785	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS34860	COG0582	viral genome integration into host DNA
EB232_RS34870	COG4974	Belongs to the 'phage' integrase family
EB232_RS34875	COG0517	IMP dehydrogenase activity
EB232_RS34885	COG3436	PFAM IS66 Orf2 family protein
EB232_RS34905	COG4948	Mandelate Racemase Muconate Lactonizing
EB232_RS34910	COG0583	DNA-binding transcription factor activity
EB232_RS34920	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB232_RS34920	COG1902	pentaerythritol trinitrate reductase activity
EB232_RS34940	COG0006	proline dipeptidase activity
EB232_RS34945	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS34950	COG1028	Short-chain dehydrogenase reductase Sdr
EB232_RS34965	COG5598	trimethylamine methyltransferase
EB232_RS34975	COG2113	Glycine betaine
EB232_RS34980	COG4176	ABC-type proline glycine betaine transport system permease component
EB232_RS35000	COG3938	Belongs to the proline racemase family
EB232_RS35005	COG0583	DNA-binding transcription factor activity
EB232_RS35010	COG1053	succinate dehydrogenase
EB232_RS35020	COG1012	belongs to the aldehyde dehydrogenase family
EB232_RS35060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB232_RS35070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EB232_RS35080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB232_RS35090	COG3842	ATPase activity
EB232_RS35095	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB232_RS35120	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EB232_RS35130	COG3621	Patatin-like phospholipase
EB232_RS35135	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EB232_RS35140	COG4644	lycopene metabolic process
EB232_RS35160	COG0326	Molecular chaperone. Has ATPase activity
EB232_RS35225	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves