locus-tag	class	description
EB230_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EB230_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EB230_RS00030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EB230_RS00045	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EB230_RS00055	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EB230_RS00060	COG5001	Diguanylate cyclase
EB230_RS00060	COG3300	MHYT domain
EB230_RS00065	COG2813	Specifically methylates the guanine in position
EB230_RS00070	COG1185	polyribonucleotide nucleotidyltransferase activity
EB230_RS00075	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EB230_RS00080	COG0598	Magnesium transport protein CorA
EB230_RS00085	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EB230_RS00090	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EB230_RS00095	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EB230_RS00110	COG0779	Required for maturation of 30S ribosomal subunits
EB230_RS00120	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EB230_RS00125	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EB230_RS00130	COG1396	sequence-specific DNA binding
EB230_RS00135	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EB230_RS00145	COG1253	flavin adenine dinucleotide binding
EB230_RS00150	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EB230_RS00155	COG1702	phosphate starvation-inducible protein PhoH
EB230_RS00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EB230_RS00175	COG1214	PFAM Peptidase M22, glycoprotease
EB230_RS00215	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EB230_RS00220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB230_RS00230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EB230_RS00240	COG0444	Belongs to the ABC transporter superfamily
EB230_RS00250	COG0601	transmembrane transport
EB230_RS00265	COG2951	lytic endotransglycosylase activity
EB230_RS00270	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EB230_RS00285	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EB230_RS00305	COG2816	NAD+ diphosphatase activity
EB230_RS00315	COG0077	Prephenate dehydratase
EB230_RS00315	COG1605	Chorismate mutase
EB230_RS00320	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EB230_RS00325	COG3474	cytochrome
EB230_RS00330	COG4166	transmembrane transport
EB230_RS00340	COG4174	ABC transporter (Permease)
EB230_RS00345	COG4239	(ABC) transporter, permease
EB230_RS00350	COG4172	Belongs to the ABC transporter superfamily
EB230_RS00355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EB230_RS00380	COG1793	dna ligase
EB230_RS00405	COG1595	DNA-templated transcription, initiation
EB230_RS00470	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EB230_RS00485	COG0601	transmembrane transport
EB230_RS00490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB230_RS00495	COG0444	Belongs to the ABC transporter superfamily
EB230_RS00525	COG1024	Enoyl-CoA hydratase
EB230_RS00530	COG1960	acyl-CoA dehydrogenase activity
EB230_RS00535	COG0251	oxidation-reduction process
EB230_RS00540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB230_RS00550	COG0436	Aminotransferase
EB230_RS00555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB230_RS00565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EB230_RS00570	COG4608	Belongs to the ABC transporter superfamily
EB230_RS00575	COG0444	Belongs to the ABC transporter superfamily
EB230_RS00580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB230_RS00585	COG0601	transmembrane transport
EB230_RS00590	COG0747	negative chemotaxis
EB230_RS00595	COG0318	PFAM AMP-dependent synthetase and ligase
EB230_RS00600	COG2264	protein methyltransferase activity
EB230_RS00605	COG0546	phosphoglycolate phosphatase activity
EB230_RS00610	COG0166	Belongs to the GPI family
EB230_RS00615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB230_RS00640	COG0129	dihydroxy-acid dehydratase activity
EB230_RS00650	COG0489	protein tyrosine kinase activity
EB230_RS00655	COG0306	phosphate transporter
EB230_RS00660	COG1392	Phosphate transport regulator
EB230_RS00665	COG0583	DNA-binding transcription factor activity
EB230_RS00680	COG3383	formate dehydrogenase (NAD+) activity
EB230_RS00685	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EB230_RS00695	COG2197	response regulator
EB230_RS00725	COG1177	transmembrane transport
EB230_RS00730	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB230_RS00735	COG3842	ATPase activity
EB230_RS00740	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EB230_RS00755	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EB230_RS00760	COG0745	RESPONSE REGULATOR receiver
EB230_RS00770	COG1959	2 iron, 2 sulfur cluster binding
EB230_RS00775	COG0492	ferredoxin-NADP+ reductase activity
EB230_RS00780	COG1349	DNA-binding transcription factor activity
EB230_RS00795	COG2226	methyltransferase
EB230_RS00805	COG0697	spore germination
EB230_RS00815	COG0402	S-adenosylhomocysteine deaminase activity
EB230_RS00820	COG1132	(ABC) transporter
EB230_RS00825	COG0129	dihydroxy-acid dehydratase activity
EB230_RS00835	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EB230_RS00840	COG0596	Alpha beta hydrolase
EB230_RS00850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB230_RS00855	COG0154	amidase activity
EB230_RS00860	COG0121	glutamine amidotransferase
EB230_RS00870	COG1522	sequence-specific DNA binding
EB230_RS00875	COG0756	dUTP diphosphatase activity
EB230_RS00880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EB230_RS00910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB230_RS00920	COG0280	phosphate acetyltransferase
EB230_RS00920	COG0281	malic enzyme
EB230_RS00925	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EB230_RS00930	COG0656	L-ascorbic acid biosynthetic process
EB230_RS00955	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EB230_RS00960	COG0728	peptidoglycan biosynthetic process
EB230_RS00965	COG0180	Tryptophanyl-tRNA synthetase
EB230_RS00975	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EB230_RS00980	COG1376	ErfK ybiS ycfS ynhG family protein
EB230_RS00980	COG1388	LysM domain
EB230_RS01025	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EB230_RS01030	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EB230_RS01040	COG1643	Atp-dependent helicase
EB230_RS01060	COG1175	transmembrane transport
EB230_RS01090	COG1461	Dihydroxyacetone kinase
EB230_RS01115	COG2376	Dihydroxyacetone kinase
EB230_RS01155	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EB230_RS01160	COG0489	protein tyrosine kinase activity
EB230_RS01160	COG3206	protein involved in exopolysaccharide biosynthesis
EB230_RS01165	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EB230_RS01170	COG1215	transferase activity, transferring glycosyl groups
EB230_RS01175	COG1215	transferase activity, transferring glycosyl groups
EB230_RS01180	COG1215	transferase activity, transferring glycosyl groups
EB230_RS01185	COG0438	transferase activity, transferring glycosyl groups
EB230_RS01200	COG2244	polysaccharide biosynthetic process
EB230_RS01205	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EB230_RS01230	COG2273	Hydrolase Family 16
EB230_RS01240	COG1215	transferase activity, transferring glycosyl groups
EB230_RS01265	COG0367	asparagine synthase
EB230_RS01275	COG1132	(ABC) transporter
EB230_RS01285	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EB230_RS01290	COG1596	polysaccharide export
EB230_RS01300	COG3307	-O-antigen
EB230_RS01305	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS01310	COG4647	ligase activity
EB230_RS01315	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
EB230_RS01320	COG0145	ligase activity
EB230_RS01325	COG2197	response regulator
EB230_RS01330	COG0022	dehydrogenase e1 component
EB230_RS01335	COG0747	negative chemotaxis
EB230_RS01350	COG3395	kinase activity
EB230_RS01365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EB230_RS01370	COG4608	Belongs to the ABC transporter superfamily
EB230_RS01380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB230_RS01385	COG0601	transmembrane transport
EB230_RS01395	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS01405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EB230_RS01430	COG1012	belongs to the aldehyde dehydrogenase family
EB230_RS01445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB230_RS01455	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB230_RS01455	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB230_RS01470	COG0431	NADPH-dependent FMN reductase
EB230_RS01505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB230_RS01515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB230_RS01520	COG1879	ABC-type sugar transport system periplasmic component
EB230_RS01525	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS01535	COG1129	ABC transporter
EB230_RS01545	COG3254	rhamnose metabolic process
EB230_RS01550	COG2721	sulfolactate sulfo-lyase activity
EB230_RS01555	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS01575	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EB230_RS01585	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EB230_RS01590	COG0539	negative regulation of cytoplasmic translation
EB230_RS01620	COG4215	(ABC) transporter
EB230_RS01630	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EB230_RS01700	COG5001	Diguanylate cyclase
EB230_RS01730	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EB230_RS01735	COG1063	alcohol dehydrogenase
EB230_RS01740	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EB230_RS01745	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EB230_RS01750	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EB230_RS01760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EB230_RS01765	COG1609	Transcriptional regulator
EB230_RS01790	COG0523	cobalamin synthesis protein
EB230_RS01805	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EB230_RS01810	COG0174	glutamine synthetase
EB230_RS01820	COG1573	uracil-dna glycosylase
EB230_RS01830	COG4702	Belongs to the UPF0303 family
EB230_RS01835	COG0402	S-adenosylhomocysteine deaminase activity
EB230_RS01845	COG0583	DNA-binding transcription factor activity
EB230_RS01850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB230_RS01860	COG0384	phenazine biosynthesis protein PhzF
EB230_RS01870	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EB230_RS01880	COG2351	hydroxyisourate hydrolase activity
EB230_RS01885	COG3195	allantoin biosynthetic process
EB230_RS01885	COG3648	Uricase
EB230_RS01890	COG3257	ureidoglycine aminohydrolase activity
EB230_RS01895	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
EB230_RS01915	COG0601	transmembrane transport
EB230_RS01930	COG4166	transmembrane transport
EB230_RS01935	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EB230_RS01940	COG1595	DNA-templated transcription, initiation
EB230_RS01955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB230_RS01960	COG1609	Transcriptional regulator
EB230_RS01965	COG1653	transport
EB230_RS01970	COG1175	transmembrane transport
EB230_RS01975	COG0395	ABC-type sugar transport system, permease component
EB230_RS01980	COG0366	Alpha amylase catalytic
EB230_RS01985	COG3842	ATPase activity
EB230_RS02015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EB230_RS02030	COG0463	Glycosyl transferase, family 2
EB230_RS02055	COG1652	LysM domain
EB230_RS02065	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EB230_RS02070	COG0745	RESPONSE REGULATOR receiver
EB230_RS02075	COG2205	protein histidine kinase activity
EB230_RS02080	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EB230_RS02085	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EB230_RS02085	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EB230_RS02095	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EB230_RS02100	COG2205	protein histidine kinase activity
EB230_RS02105	COG3178	'Phosphotransferase
EB230_RS02110	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EB230_RS02115	COG2887	Belongs to the helicase family. UvrD subfamily
EB230_RS02120	COG1074	ATP-dependent DNA helicase activity
EB230_RS02140	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EB230_RS02145	COG0159	tryptophan synthase activity
EB230_RS02150	COG0133	tryptophan synthase activity
EB230_RS02155	COG0135	phosphoribosylanthranilate isomerase activity
EB230_RS02175	COG3135	benzoate transporter
EB230_RS02185	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EB230_RS02195	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EB230_RS02200	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EB230_RS02205	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EB230_RS02215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EB230_RS02215	COG0072	phenylalanine-tRNA ligase activity
EB230_RS02265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EB230_RS02295	COG1250	3-hydroxyacyl-CoA dehydrogenase
EB230_RS02305	COG3246	L-lysine catabolic process to acetate
EB230_RS02310	COG4977	sequence-specific DNA binding
EB230_RS02325	COG2115	Belongs to the xylose isomerase family
EB230_RS02335	COG1070	Carbohydrate kinase
EB230_RS02345	COG3468	outer membrane autotransporter barrel domain protein
EB230_RS02350	COG1280	lysine exporter protein (LysE YggA)
EB230_RS02355	COG1376	ErfK ybiS ycfS ynhG family protein
EB230_RS02355	COG1388	LysM domain
EB230_RS02360	COG0205	6-phosphofructokinase activity
EB230_RS02365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EB230_RS02375	COG1072	(Pantothenic acid kinase))
EB230_RS02380	COG0140	phosphoribosyl-ATP diphosphatase activity
EB230_RS02385	COG0107	imidazoleglycerol-phosphate synthase activity
EB230_RS02395	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EB230_RS02405	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EB230_RS02415	COG0131	Imidazoleglycerol-phosphate dehydratase
EB230_RS02420	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EB230_RS02435	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EB230_RS02465	COG1609	Transcriptional regulator
EB230_RS02490	COG4211	Belongs to the binding-protein-dependent transport system permease family
EB230_RS02500	COG0673	inositol 2-dehydrogenase activity
EB230_RS02505	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS02520	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EB230_RS02545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB230_RS02550	COG3962	Belongs to the TPP enzyme family
EB230_RS02555	COG1082	Xylose isomerase domain protein TIM barrel
EB230_RS02565	COG3718	enzyme involved in inositol metabolism
EB230_RS02570	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EB230_RS02575	COG3454	Phosphonate metabolism
EB230_RS02580	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EB230_RS02595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB230_RS02605	COG0765	amino acid transport
EB230_RS02615	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS02620	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS02625	COG1129	ABC transporter
EB230_RS02630	COG1879	ABC-type sugar transport system periplasmic component
EB230_RS02640	COG2188	Transcriptional regulator
EB230_RS02650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EB230_RS02655	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EB230_RS02660	COG4948	Mandelate Racemase Muconate Lactonizing
EB230_RS02665	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS02670	COG3959	Transketolase, thiamine diphosphate binding domain
EB230_RS02675	COG3958	Transketolase
EB230_RS02680	COG4948	Mandelate Racemase Muconate Lactonizing
EB230_RS02685	COG1609	Transcriptional regulator
EB230_RS02695	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS02700	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS02715	COG1609	Transcriptional regulator
EB230_RS02720	COG0765	amino acid transport
EB230_RS02725	COG4597	amino acid ABC transporter
EB230_RS02730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB230_RS02740	COG1116	anion transmembrane transporter activity
EB230_RS02740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EB230_RS02770	COG2824	Alkylphosphonate utilization operon protein PhnA
EB230_RS02790	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EB230_RS02800	COG0651	ATP synthesis coupled electron transport
EB230_RS02815	COG0651	ATP synthesis coupled electron transport
EB230_RS02820	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EB230_RS02820	COG0649	NAD binding
EB230_RS02825	COG3260	NADH ubiquinone oxidoreductase 20
EB230_RS02840	COG0583	DNA-binding transcription factor activity
EB230_RS02860	COG0745	RESPONSE REGULATOR receiver
EB230_RS02925	COG3119	arylsulfatase activity
EB230_RS02935	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EB230_RS02965	COG1686	Belongs to the peptidase S11 family
EB230_RS02975	COG1072	(Pantothenic acid kinase))
EB230_RS02985	COG0625	glutathione transferase activity
EB230_RS03000	COG0829	nickel cation binding
EB230_RS03005	COG0831	urea catabolic process
EB230_RS03010	COG3813	Protein conserved in bacteria
EB230_RS03020	COG0832	Belongs to the urease beta subunit family
EB230_RS03035	COG0804	urea catabolic process
EB230_RS03045	COG0625	glutathione transferase activity
EB230_RS03050	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
EB230_RS03055	COG0830	nickel cation binding
EB230_RS03065	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EB230_RS03075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EB230_RS03090	COG0583	DNA-binding transcription factor activity
EB230_RS03100	COG1175	transmembrane transport
EB230_RS03135	COG3842	ATPase activity
EB230_RS03140	COG1063	alcohol dehydrogenase
EB230_RS03145	COG0395	ABC-type sugar transport system, permease component
EB230_RS03170	COG0534	Mate efflux family protein
EB230_RS03180	COG5001	Diguanylate cyclase
EB230_RS03185	COG2197	response regulator
EB230_RS03190	COG0765	amino acid transport
EB230_RS03195	COG0765	amino acid transport
EB230_RS03210	COG0583	DNA-binding transcription factor activity
EB230_RS03215	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EB230_RS03230	COG0559	Belongs to the binding-protein-dependent transport system permease family
EB230_RS03255	COG1335	isochorismatase
EB230_RS03260	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EB230_RS03285	COG1846	Transcriptional regulator
EB230_RS03290	COG1879	ABC-type sugar transport system periplasmic component
EB230_RS03295	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS03310	COG0483	inositol monophosphate 1-phosphatase activity
EB230_RS03315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB230_RS03320	COG0628	permease
EB230_RS03335	COG2076	Multidrug Resistance protein
EB230_RS03355	COG2226	methyltransferase
EB230_RS03370	COG0242	peptide deformylase activity
EB230_RS03375	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EB230_RS03385	COG0101	tRNA pseudouridine synthase activity
EB230_RS03395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB230_RS03400	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EB230_RS03420	COG2171	N-acyltransferase activity
EB230_RS03435	COG3706	GGDEF domain
EB230_RS03470	COG3186	Phenylalanine-4-hydroxylase
EB230_RS03475	COG1522	sequence-specific DNA binding
EB230_RS03480	COG1032	radical SAM domain protein
EB230_RS03485	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EB230_RS03505	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EB230_RS03510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EB230_RS03530	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EB230_RS03550	COG1566	PFAM secretion protein HlyD family protein
EB230_RS03560	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EB230_RS03565	COG0706	membrane insertase activity
EB230_RS03570	COG0594	ribonuclease P activity
EB230_RS03575	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EB230_RS03580	COG4191	Histidine kinase
EB230_RS03595	COG0583	DNA-binding transcription factor activity
EB230_RS03605	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EB230_RS03625	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EB230_RS03630	COG1116	anion transmembrane transporter activity
EB230_RS03650	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS03675	COG3842	ATPase activity
EB230_RS03680	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB230_RS03690	COG0405	Gamma-glutamyltransferase
EB230_RS03695	COG0318	PFAM AMP-dependent synthetase and ligase
EB230_RS03700	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EB230_RS03770	COG0747	negative chemotaxis
EB230_RS03800	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EB230_RS03805	COG2011	ABC-type metal ion transport system permease component
EB230_RS03825	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB230_RS03830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB230_RS03850	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EB230_RS03855	COG1012	belongs to the aldehyde dehydrogenase family
EB230_RS03860	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS03865	COG0179	Fumarylacetoacetate (FAA) hydrolase
EB230_RS03875	COG0673	inositol 2-dehydrogenase activity
EB230_RS03880	COG0395	ABC-type sugar transport system, permease component
EB230_RS03885	COG1175	transmembrane transport
EB230_RS03890	COG1653	transport
EB230_RS03895	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EB230_RS03900	COG2971	BadF BadG BcrA BcrD
EB230_RS03905	COG2188	Transcriptional regulator
EB230_RS03910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EB230_RS03915	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EB230_RS03920	COG0579	oxidoreductase
EB230_RS03925	COG4178	(ABC) transporter
EB230_RS03930	COG0318	PFAM AMP-dependent synthetase and ligase
EB230_RS03955	COG0443	Heat shock 70 kDa protein
EB230_RS03960	COG0484	heat shock protein binding
EB230_RS03965	COG3963	phosphatidate phosphatase activity
EB230_RS03975	COG0284	orotidine-5'-phosphate decarboxylase activity
EB230_RS03985	COG0640	Transcriptional regulator
EB230_RS04010	COG3386	PFAM SMP-30 Gluconolaconase
EB230_RS04015	COG0800	Aldolase
EB230_RS04020	COG3734	2-keto-3-deoxy-galactonokinase
EB230_RS04025	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS04030	COG5001	Diguanylate cyclase
EB230_RS04050	COG0189	ligase activity
EB230_RS04060	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EB230_RS04095	COG0076	glutamate decarboxylase activity
EB230_RS04130	COG3038	cytochrome b561
EB230_RS04150	COG0588	phosphoglycerate mutase activity
EB230_RS04155	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EB230_RS04160	COG1132	(ABC) transporter
EB230_RS04165	COG0837	glucose binding
EB230_RS04170	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
EB230_RS04180	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EB230_RS04190	COG1968	undecaprenyl-diphosphatase activity
EB230_RS04195	COG0792	nuclease activity
EB230_RS04200	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EB230_RS04225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EB230_RS04230	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EB230_RS04240	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EB230_RS04245	COG1420	regulation of RNA biosynthetic process
EB230_RS04275	COG4941	Belongs to the sigma-70 factor family
EB230_RS04280	COG3795	YCII-related domain
EB230_RS04300	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EB230_RS04340	COG0842	Transport permease protein
EB230_RS04345	COG1131	(ABC) transporter
EB230_RS04355	COG1309	transcriptional regulator
EB230_RS04360	COG2954	triphosphatase activity
EB230_RS04390	COG2094	Belongs to the DNA glycosylase MPG family
EB230_RS04400	COG0671	phosphoesterase, PA-phosphatase related
EB230_RS04415	COG2197	response regulator
EB230_RS04435	COG3634	alkyl hydroperoxide reductase activity
EB230_RS04450	COG3321	synthase
EB230_RS04450	COG0604	alcohol dehydrogenase
EB230_RS04450	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS04455	COG0842	Transport permease protein
EB230_RS04460	COG1131	(ABC) transporter
EB230_RS04465	COG1271	oxidase subunit
EB230_RS04470	COG1294	oxidase, subunit
EB230_RS04495	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EB230_RS04515	COG0481	GTPase activity
EB230_RS04540	COG0747	negative chemotaxis
EB230_RS04545	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EB230_RS04550	COG3030	protein affecting phage T7 exclusion by the F plasmid
EB230_RS04590	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EB230_RS04600	COG1116	anion transmembrane transporter activity
EB230_RS04605	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB230_RS04610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB230_RS04615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EB230_RS04625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB230_RS04630	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EB230_RS04635	COG4521	taurine ABC transporter
EB230_RS04640	COG1959	2 iron, 2 sulfur cluster binding
EB230_RS04655	COG0626	cystathionine gamma-synthase activity
EB230_RS04665	COG0006	proline dipeptidase activity
EB230_RS04670	COG1335	isochorismatase
EB230_RS04680	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EB230_RS04685	COG0237	dephospho-CoA kinase activity
EB230_RS04690	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EB230_RS04695	COG0424	maF-like protein
EB230_RS04700	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EB230_RS04705	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EB230_RS04715	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EB230_RS04720	COG1331	Highly conserved protein containing a thioredoxin domain
EB230_RS04725	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EB230_RS04730	COG0445	tRNA wobble uridine modification
EB230_RS04735	COG0357	Ribosomal RNA small subunit methyltransferase G
EB230_RS04805	COG0463	Glycosyl transferase, family 2
EB230_RS04810	COG0671	phosphoesterase, PA-phosphatase related
EB230_RS04820	COG1136	(ABC) transporter
EB230_RS04825	COG1136	(ABC) transporter
EB230_RS04835	COG0642	Histidine kinase
EB230_RS04860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB230_RS04870	COG3842	ATPase activity
EB230_RS04875	COG1177	transmembrane transport
EB230_RS04880	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB230_RS04905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EB230_RS04925	COG3964	amidohydrolase
EB230_RS04935	COG2072	flavoprotein involved in K transport
EB230_RS04940	COG1737	Transcriptional regulator
EB230_RS04945	COG1116	anion transmembrane transporter activity
EB230_RS04960	COG0673	inositol 2-dehydrogenase activity
EB230_RS05000	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EB230_RS05005	COG2835	tetraacyldisaccharide 4'-kinase activity
EB230_RS05010	COG0587	DNA-directed DNA polymerase activity
EB230_RS05030	COG2301	Belongs to the HpcH HpaI aldolase family
EB230_RS05045	COG0745	RESPONSE REGULATOR receiver
EB230_RS05050	COG2205	protein histidine kinase activity
EB230_RS05075	COG0640	Transcriptional regulator
EB230_RS05080	COG0066	3-isopropylmalate dehydratase activity
EB230_RS05100	COG0251	oxidation-reduction process
EB230_RS05110	COG0473	3-isopropylmalate dehydrogenase activity
EB230_RS05125	COG0513	Belongs to the DEAD box helicase family
EB230_RS05130	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EB230_RS05145	COG3781	membrane
EB230_RS05175	COG0228	four-way junction DNA binding
EB230_RS05180	COG1605	Chorismate mutase
EB230_RS05180	COG0287	Prephenate dehydrogenase
EB230_RS05185	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EB230_RS05190	COG1266	CAAX protease self-immunity
EB230_RS05220	COG0137	argininosuccinate synthase activity
EB230_RS05240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB230_RS05245	COG1609	Transcriptional regulator
EB230_RS05285	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EB230_RS05305	COG3339	Conserved Protein
EB230_RS05310	COG2154	pterin-4-alpha-carbinolamine dehydratase
EB230_RS05315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EB230_RS05320	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EB230_RS05330	COG1136	(ABC) transporter
EB230_RS05335	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EB230_RS05340	COG0670	Belongs to the BI1 family
EB230_RS05365	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EB230_RS05370	COG4133	protoheme IX ABC transporter activity
EB230_RS05375	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EB230_RS05385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EB230_RS05405	COG0431	NADPH-dependent FMN reductase
EB230_RS05415	COG2917	probably involved in intracellular septation
EB230_RS05420	COG0552	protein localization to endoplasmic reticulum
EB230_RS05425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EB230_RS05430	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EB230_RS05460	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EB230_RS05465	COG0039	L-malate dehydrogenase activity
EB230_RS05470	COG0045	succinate-CoA ligase (ADP-forming) activity
EB230_RS05485	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EB230_RS05490	COG0567	Dehydrogenase, E1 component
EB230_RS05495	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB230_RS05505	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS05525	COG4974	Belongs to the 'phage' integrase family
EB230_RS05530	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EB230_RS05535	COG0336	Belongs to the RNA methyltransferase TrmD family
EB230_RS05545	COG0335	large ribosomal subunit rRNA binding
EB230_RS05550	COG1764	response to oxidative stress
EB230_RS05555	COG1846	Transcriptional regulator
EB230_RS05565	COG0765	amino acid transport
EB230_RS05575	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EB230_RS05580	COG3706	GGDEF domain
EB230_RS05585	COG3706	GGDEF domain
EB230_RS05625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB230_RS05635	COG3132	Protein of unknown function, DUF480
EB230_RS05655	COG1764	response to oxidative stress
EB230_RS05665	COG3795	YCII-related domain
EB230_RS05675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EB230_RS05680	COG1946	Acyl-CoA thioesterase
EB230_RS05685	COG0347	Belongs to the P(II) protein family
EB230_RS05690	COG0004	ammonium transporteR
EB230_RS05700	COG1674	ftsk spoiiie
EB230_RS05700	COG2261	transglycosylase associated protein
EB230_RS05705	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EB230_RS05725	COG0745	RESPONSE REGULATOR receiver
EB230_RS05740	COG0583	DNA-binding transcription factor activity
EB230_RS05755	COG2264	protein methyltransferase activity
EB230_RS05770	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EB230_RS05775	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EB230_RS05780	COG0181	hydroxymethylbilane synthase activity
EB230_RS05805	COG0519	Catalyzes the synthesis of GMP from XMP
EB230_RS05805	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EB230_RS05825	COG4957	zinc ion binding
EB230_RS05840	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EB230_RS05850	COG1879	ABC-type sugar transport system periplasmic component
EB230_RS05855	COG1129	ABC transporter
EB230_RS05865	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS05870	COG1309	transcriptional regulator
EB230_RS05875	COG2814	Major facilitator Superfamily
EB230_RS05880	COG1024	Enoyl-CoA hydratase
EB230_RS05880	COG1250	3-hydroxyacyl-CoA dehydrogenase
EB230_RS05885	COG4566	intracellular signal transduction
EB230_RS05890	COG3842	ATPase activity
EB230_RS05895	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EB230_RS05900	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB230_RS05905	COG1177	transmembrane transport
EB230_RS05910	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS05925	COG1012	belongs to the aldehyde dehydrogenase family
EB230_RS05950	COG3842	ATPase activity
EB230_RS05955	COG1177	transmembrane transport
EB230_RS05960	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB230_RS05985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB230_RS05990	COG1414	Transcriptional regulator
EB230_RS05995	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EB230_RS06000	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EB230_RS06005	COG0183	Belongs to the thiolase family
EB230_RS06075	COG0848	biopolymer transport protein
EB230_RS06080	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EB230_RS06120	COG1872	DUF167
EB230_RS06125	COG1737	Transcriptional regulator
EB230_RS06150	COG0395	ABC-type sugar transport system, permease component
EB230_RS06180	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EB230_RS06190	COG1704	LemA family
EB230_RS06195	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EB230_RS06200	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EB230_RS06210	COG1247	-acetyltransferase
EB230_RS06215	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EB230_RS06225	COG1309	transcriptional regulator
EB230_RS06230	COG2271	Major facilitator Superfamily
EB230_RS06270	COG2270	Major facilitator Superfamily
EB230_RS06275	COG0138	bifunctional purine biosynthesis protein purh
EB230_RS06285	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EB230_RS06285	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EB230_RS06290	COG0501	Belongs to the peptidase M48B family
EB230_RS06305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EB230_RS06330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EB230_RS06335	COG5425	PFAM Usg family protein
EB230_RS06345	COG0667	Aldo Keto reductase
EB230_RS06350	COG2814	Major facilitator Superfamily
EB230_RS06355	COG0583	DNA-binding transcription factor activity
EB230_RS06360	COG0667	Aldo Keto reductase
EB230_RS06375	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EB230_RS06380	COG0495	leucyl-tRNA aminoacylation
EB230_RS06395	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EB230_RS06415	COG1794	racemase activity, acting on amino acids and derivatives
EB230_RS06425	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EB230_RS06430	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EB230_RS06435	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EB230_RS06440	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EB230_RS06445	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EB230_RS06450	COG0246	Mannitol dehydrogenase
EB230_RS06455	COG1904	glucuronate isomerase
EB230_RS06490	COG0514	ATP-dependent DNA helicase (RecQ)
EB230_RS06500	COG0477	Major facilitator Superfamily
EB230_RS06515	COG1566	PFAM secretion protein HlyD family protein
EB230_RS06545	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EB230_RS06550	COG0583	DNA-binding transcription factor activity
EB230_RS06555	COG0667	Aldo Keto reductase
EB230_RS06570	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EB230_RS06570	COG3743	rRNA binding
EB230_RS06575	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EB230_RS06580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EB230_RS06585	COG0456	acetyltransferase
EB230_RS06595	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EB230_RS06600	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EB230_RS06605	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EB230_RS06610	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EB230_RS06635	COG0668	transmembrane transport
EB230_RS06640	COG0799	negative regulation of ribosome biogenesis
EB230_RS06645	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EB230_RS06655	COG0793	Belongs to the peptidase S41A family
EB230_RS06665	COG0494	nUDIX hydrolase
EB230_RS06670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EB230_RS06675	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EB230_RS06685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB230_RS06725	COG1733	regulation of RNA biosynthetic process
EB230_RS06740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EB230_RS06745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB230_RS06780	COG0683	leucine binding
EB230_RS06785	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EB230_RS06790	COG3750	Belongs to the UPF0335 family
EB230_RS06805	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EB230_RS06830	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EB230_RS06835	COG1692	metallophosphoesterase
EB230_RS06840	COG0861	Integral membrane protein TerC family
EB230_RS06870	COG0217	transcriptional regulatory protein
EB230_RS06885	COG0702	epimerase
EB230_RS06895	COG0254	rRNA binding
EB230_RS06900	COG1132	(ABC) transporter
EB230_RS06905	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EB230_RS06930	COG1272	protein, Hemolysin III
EB230_RS06935	COG0483	inositol monophosphate 1-phosphatase activity
EB230_RS06940	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EB230_RS06945	COG0583	DNA-binding transcription factor activity
EB230_RS06970	COG1522	sequence-specific DNA binding
EB230_RS06975	COG2226	methyltransferase
EB230_RS07000	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EB230_RS07005	COG0632	four-way junction helicase activity
EB230_RS07010	COG2255	four-way junction helicase activity
EB230_RS07015	COG1408	metallophosphoesterase
EB230_RS07025	COG0824	Thioesterase
EB230_RS07045	COG0848	biopolymer transport protein
EB230_RS07055	COG0823	Involved in the tonB-independent uptake of proteins
EB230_RS07060	COG2885	chlorophyll binding
EB230_RS07070	COG0037	tRNA processing
EB230_RS07075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EB230_RS07090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EB230_RS07110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EB230_RS07135	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EB230_RS07165	COG4143	(ABC) transporter
EB230_RS07175	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EB230_RS07190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB230_RS07200	COG1126	abc transporter atp-binding protein
EB230_RS07205	COG1329	Transcriptional regulator
EB230_RS07210	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EB230_RS07225	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS07230	COG0183	Belongs to the thiolase family
EB230_RS07235	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
EB230_RS07255	COG0372	Belongs to the citrate synthase family
EB230_RS07260	COG0372	Belongs to the citrate synthase family
EB230_RS07295	COG0583	DNA-binding transcription factor activity
EB230_RS07300	COG2223	nitrite transmembrane transporter activity
EB230_RS07320	COG0469	pyruvate kinase activity
EB230_RS07325	COG1376	ErfK ybiS ycfS ynhG family protein
EB230_RS07335	COG0457	Tetratricopeptide repeat
EB230_RS07340	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EB230_RS07350	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EB230_RS07375	COG1921	L-seryl-tRNASec selenium transferase activity
EB230_RS07390	COG0765	amino acid transport
EB230_RS07395	COG0765	amino acid transport
EB230_RS07420	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EB230_RS07425	COG1196	nuclear chromosome segregation
EB230_RS07425	COG0739	heme binding
EB230_RS07425	COG0741	lytic transglycosylase activity
EB230_RS07440	COG5002	protein histidine kinase activity
EB230_RS07440	COG0784	Response regulator, receiver
EB230_RS07440	COG2205	protein histidine kinase activity
EB230_RS07445	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS07450	COG0142	geranyltranstransferase activity
EB230_RS07455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EB230_RS07460	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EB230_RS07530	COG0640	Transcriptional regulator
EB230_RS07585	COG0346	lactoylglutathione lyase activity
EB230_RS07610	COG3588	fructose-bisphosphate aldolase
EB230_RS07615	COG0126	phosphoglycerate kinase activity
EB230_RS07645	COG0450	alkyl hydroperoxide reductase
EB230_RS07650	COG3453	Protein conserved in bacteria
EB230_RS07650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EB230_RS07655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EB230_RS07660	COG0564	pseudouridine synthase activity
EB230_RS07670	COG0346	lactoylglutathione lyase activity
EB230_RS07730	COG0625	glutathione transferase activity
EB230_RS07755	COG0784	Response regulator, receiver
EB230_RS07755	COG2205	protein histidine kinase activity
EB230_RS07755	COG5002	protein histidine kinase activity
EB230_RS07760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EB230_RS07765	COG0573	inorganic phosphate transmembrane transporter activity
EB230_RS07770	COG0581	inorganic phosphate transmembrane transporter activity
EB230_RS07775	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EB230_RS07780	COG0704	Plays a role in the regulation of phosphate uptake
EB230_RS07785	COG0745	RESPONSE REGULATOR receiver
EB230_RS07790	COG1940	carbohydrate kinase activity
EB230_RS07795	COG4213	ABC transporter substrate-binding protein
EB230_RS07800	COG4214	carbohydrate transport
EB230_RS07805	COG1129	ABC transporter
EB230_RS07830	COG2202	Pas domain
EB230_RS07830	COG3920	Histidine kinase
EB230_RS07840	COG0784	Response regulator, receiver
EB230_RS07855	COG0784	Response regulator, receiver
EB230_RS07860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EB230_RS07875	COG3920	Histidine kinase
EB230_RS07900	COG0346	lactoylglutathione lyase activity
EB230_RS07905	COG0400	carboxylic ester hydrolase activity
EB230_RS07940	COG2226	methyltransferase
EB230_RS07960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB230_RS07965	COG3842	ATPase activity
EB230_RS07975	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB230_RS07985	COG0667	Aldo Keto reductase
EB230_RS07995	COG4638	Rieske (2fe-2S)
EB230_RS08005	COG2199	diguanylate cyclase activity
EB230_RS08005	COG2203	Gaf domain
EB230_RS08005	COG2200	EAL domain
EB230_RS08010	COG0745	RESPONSE REGULATOR receiver
EB230_RS08015	COG0745	RESPONSE REGULATOR receiver
EB230_RS08035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EB230_RS08055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EB230_RS08060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB230_RS08065	COG3842	ATPase activity
EB230_RS08090	COG1653	transport
EB230_RS08095	COG1940	carbohydrate kinase activity
EB230_RS08095	COG1846	Transcriptional regulator
EB230_RS08100	COG0306	phosphate transporter
EB230_RS08110	COG4689	acetoacetate decarboxylase
EB230_RS08115	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS08125	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EB230_RS08135	COG3842	ATPase activity
EB230_RS08145	COG1175	transmembrane transport
EB230_RS08150	COG0395	ABC-type sugar transport system, permease component
EB230_RS08160	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EB230_RS08165	COG0022	dehydrogenase e1 component
EB230_RS08165	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB230_RS08170	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB230_RS08180	COG2390	Transcriptional regulator
EB230_RS08185	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EB230_RS08195	COG3842	ATPase activity
EB230_RS08200	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EB230_RS08220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EB230_RS08240	COG3732	PTS system glucitol sorbitol-specific
EB230_RS08260	COG2390	Transcriptional regulator
EB230_RS08270	COG1070	Carbohydrate kinase
EB230_RS08295	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS08305	COG1082	Xylose isomerase domain protein TIM barrel
EB230_RS08315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EB230_RS08330	COG1473	amidohydrolase
EB230_RS08340	COG0523	cobalamin synthesis protein
EB230_RS08345	COG0425	Belongs to the sulfur carrier protein TusA family
EB230_RS08355	COG0825	malonyl-CoA metabolic process
EB230_RS08360	COG4974	Belongs to the 'phage' integrase family
EB230_RS08370	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EB230_RS08375	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EB230_RS08380	COG4536	flavin adenine dinucleotide binding
EB230_RS08390	COG0028	Belongs to the TPP enzyme family
EB230_RS08435	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EB230_RS08440	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EB230_RS08465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EB230_RS08470	COG2226	methyltransferase
EB230_RS08475	COG4178	(ABC) transporter
EB230_RS08490	COG2813	Specifically methylates the guanine in position
EB230_RS08490	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EB230_RS08495	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EB230_RS08500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EB230_RS08505	COG0287	Prephenate dehydrogenase
EB230_RS08525	COG0667	Aldo Keto reductase
EB230_RS08570	COG2884	Cell division ATP-binding protein ftsE
EB230_RS08580	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EB230_RS08595	COG0583	DNA-binding transcription factor activity
EB230_RS08615	COG0019	diaminopimelate decarboxylase activity
EB230_RS08625	COG0165	Argininosuccinate lyase
EB230_RS08630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EB230_RS08635	COG5001	Diguanylate cyclase
EB230_RS08635	COG3300	MHYT domain
EB230_RS08640	COG1653	transport
EB230_RS08645	COG1175	transmembrane transport
EB230_RS08655	COG3842	ATPase activity
EB230_RS08660	COG3842	ATPase activity
EB230_RS08685	COG3447	MASE1 domain protein
EB230_RS08685	COG5002	protein histidine kinase activity
EB230_RS08685	COG5001	Diguanylate cyclase
EB230_RS08690	COG1250	3-hydroxyacyl-CoA dehydrogenase
EB230_RS08695	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EB230_RS08700	COG2086	electron transfer activity
EB230_RS08720	COG0300	oxidoreductase activity
EB230_RS08730	COG0697	spore germination
EB230_RS08735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EB230_RS08755	COG1238	metal cluster binding
EB230_RS08785	COG0653	protein targeting
EB230_RS08790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EB230_RS08800	COG2814	Major facilitator Superfamily
EB230_RS08805	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EB230_RS08810	COG0456	acetyltransferase
EB230_RS08810	COG0454	-acetyltransferase
EB230_RS08815	COG0494	nUDIX hydrolase
EB230_RS08835	COG1040	competence protein
EB230_RS08845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EB230_RS08855	COG1846	Transcriptional regulator
EB230_RS08865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EB230_RS08875	COG0527	aspartate kinase activity
EB230_RS08885	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EB230_RS08890	COG2890	protein-(glutamine-N5) methyltransferase activity
EB230_RS08900	COG0542	response to heat
EB230_RS08910	COG1376	ErfK ybiS ycfS ynhG family protein
EB230_RS08915	COG3548	integral membrane protein
EB230_RS08920	COG0477	Major facilitator Superfamily
EB230_RS08925	COG0739	heme binding
EB230_RS08960	COG3609	addiction module antidote protein, CC2985 family
EB230_RS09020	COG0444	Belongs to the ABC transporter superfamily
EB230_RS09025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB230_RS09030	COG0601	transmembrane transport
EB230_RS09035	COG0747	negative chemotaxis
EB230_RS09050	COG5564	TIM-barrel signal transduction protein
EB230_RS09055	COG5441	Belongs to the UPF0261 family
EB230_RS09070	COG1175	transmembrane transport
EB230_RS09085	COG3842	ATPase activity
EB230_RS09090	COG3842	ATPase activity
EB230_RS09130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EB230_RS09140	COG4948	Mandelate Racemase Muconate Lactonizing
EB230_RS09155	COG0673	inositol 2-dehydrogenase activity
EB230_RS09160	COG1082	Xylose isomerase domain protein TIM barrel
EB230_RS09165	COG3639	organic phosphonate transmembrane transporter activity
EB230_RS09180	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EB230_RS09195	COG4778	phosphonate C-P lyase system protein PhnL
EB230_RS09200	COG4107	phosphonate C-P lyase system protein PhnK
EB230_RS09205	COG3627	carbon phosphorus lyase activity
EB230_RS09210	COG0346	lactoylglutathione lyase activity
EB230_RS09215	COG3626	phosphonate metabolism
EB230_RS09220	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
EB230_RS09225	COG3624	Phosphonate C-P lyase system protein PhnG
EB230_RS09230	COG2188	Transcriptional regulator
EB230_RS09235	COG1063	alcohol dehydrogenase
EB230_RS09240	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS09245	COG1129	ABC transporter
EB230_RS09250	COG1879	ABC-type sugar transport system periplasmic component
EB230_RS09260	COG2721	sulfolactate sulfo-lyase activity
EB230_RS09265	COG1802	Transcriptional regulator
EB230_RS09275	COG2847	Copper chaperone PCu(A)C
EB230_RS09290	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EB230_RS09305	COG1175	transmembrane transport
EB230_RS09310	COG0395	ABC-type sugar transport system, permease component
EB230_RS09315	COG3842	ATPase activity
EB230_RS09330	COG0667	Aldo Keto reductase
EB230_RS09360	COG0735	belongs to the Fur family
EB230_RS09365	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EB230_RS09365	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EB230_RS09370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB230_RS09405	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS09415	COG2207	Transcriptional regulator
EB230_RS09420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EB230_RS09420	COG4651	solute:proton antiporter activity
EB230_RS09430	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EB230_RS09430	COG1648	precorrin-2 dehydrogenase activity
EB230_RS09440	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EB230_RS09445	COG0175	sulfate reduction
EB230_RS09465	COG3239	Fatty acid desaturase
EB230_RS09475	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EB230_RS09480	COG2860	membrane
EB230_RS09495	COG0604	alcohol dehydrogenase
EB230_RS09500	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EB230_RS09505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EB230_RS09510	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EB230_RS09510	COG0116	Belongs to the methyltransferase superfamily
EB230_RS09515	COG2378	regulation of single-species biofilm formation
EB230_RS09530	COG2423	ornithine cyclodeaminase activity
EB230_RS09540	COG0776	regulation of translation
EB230_RS09545	COG0616	signal peptide processing
EB230_RS09555	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EB230_RS09560	COG1137	ATPase activity
EB230_RS09565	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EB230_RS09570	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EB230_RS09575	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EB230_RS09590	COG1957	nucleoside hydrolase
EB230_RS09595	COG1280	lysine exporter protein (LysE YggA)
EB230_RS09600	COG0154	amidase activity
EB230_RS09605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB230_RS09635	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EB230_RS09660	COG5002	protein histidine kinase activity
EB230_RS09660	COG5001	Diguanylate cyclase
EB230_RS09685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EB230_RS09715	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EB230_RS09720	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EB230_RS09725	COG2226	methyltransferase
EB230_RS09730	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EB230_RS09735	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EB230_RS09745	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EB230_RS09750	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EB230_RS09775	COG2900	Belongs to the SlyX family
EB230_RS09790	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EB230_RS09820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EB230_RS09850	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EB230_RS09860	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EB230_RS09865	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EB230_RS09870	COG2205	protein histidine kinase activity
EB230_RS09880	COG2814	Major facilitator Superfamily
EB230_RS09900	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EB230_RS09910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB230_RS09925	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB230_RS09925	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB230_RS09945	COG0673	inositol 2-dehydrogenase activity
EB230_RS09980	COG1960	acyl-CoA dehydrogenase activity
EB230_RS09995	COG0463	Glycosyl transferase, family 2
EB230_RS10010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EB230_RS10030	COG0531	amino acid
EB230_RS10065	COG3842	ATPase activity
EB230_RS10090	COG2814	Major facilitator Superfamily
EB230_RS10105	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS10115	COG3842	ATPase activity
EB230_RS10120	COG0395	ABC-type sugar transport system, permease component
EB230_RS10125	COG1175	transmembrane transport
EB230_RS10130	COG1653	transport
EB230_RS10135	COG1012	belongs to the aldehyde dehydrogenase family
EB230_RS10140	COG1024	Enoyl-CoA hydratase
EB230_RS10155	COG1609	Transcriptional regulator
EB230_RS10170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EB230_RS10205	COG0483	inositol monophosphate 1-phosphatase activity
EB230_RS10230	COG0071	Belongs to the small heat shock protein (HSP20) family
EB230_RS10240	COG0069	glutamate synthase activity
EB230_RS10240	COG0070	glutamate synthase
EB230_RS10240	COG0067	glutamate synthase
EB230_RS10255	COG2951	lytic endotransglycosylase activity
EB230_RS10260	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EB230_RS10280	COG0330	HflC and HflK could
EB230_RS10285	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EB230_RS10285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB230_RS10290	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EB230_RS10295	COG0737	Belongs to the 5'-nucleotidase family
EB230_RS10305	COG5310	Homospermidine synthase
EB230_RS10330	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EB230_RS10330	COG3743	rRNA binding
EB230_RS10340	COG2204	response regulator
EB230_RS10345	COG3108	Peptidase M15
EB230_RS10360	COG2207	Transcriptional regulator
EB230_RS10365	COG0300	oxidoreductase activity
EB230_RS10370	COG0800	Aldolase
EB230_RS10385	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS10390	COG3795	YCII-related domain
EB230_RS10405	COG1230	cation diffusion facilitator family transporter
EB230_RS10415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EB230_RS10430	COG0583	DNA-binding transcription factor activity
EB230_RS10435	COG0154	amidase activity
EB230_RS10475	COG4106	trans-aconitate 2-methyltransferase activity
EB230_RS10505	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EB230_RS10520	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EB230_RS10560	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB230_RS10565	COG1177	transmembrane transport
EB230_RS10570	COG3842	ATPase activity
EB230_RS10585	COG2814	Major facilitator Superfamily
EB230_RS10595	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EB230_RS10600	COG5443	negative regulation of bacterial-type flagellum assembly
EB230_RS10620	COG1749	Flagellar hook protein flgE
EB230_RS10660	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EB230_RS10665	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EB230_RS10670	COG1338	Plays a role in the flagellum-specific transport system
EB230_RS10680	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EB230_RS10690	COG1706	bacterial-type flagellum-dependent cell motility
EB230_RS10695	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
EB230_RS10700	COG4786	Flagellar basal body rod
EB230_RS10705	COG1677	Flagellar hook-basal body complex protein FliE
EB230_RS10710	COG1558	bacterial-type flagellum-dependent cell motility
EB230_RS10715	COG1815	bacterial-type flagellum-dependent cell motility
EB230_RS10725	COG1157	protein secretion by the type III secretion system
EB230_RS10730	COG4786	Flagellar basal body rod
EB230_RS10740	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EB230_RS10745	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EB230_RS10750	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EB230_RS10755	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EB230_RS10760	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EB230_RS10775	COG2771	luxR family
EB230_RS10785	COG1309	transcriptional regulator
EB230_RS10790	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EB230_RS10795	COG3842	ATPase activity
EB230_RS10800	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB230_RS10805	COG1177	transmembrane transport
EB230_RS10825	COG2183	response to ionizing radiation
EB230_RS10830	COG0583	DNA-binding transcription factor activity
EB230_RS10835	COG1960	acyl-CoA dehydrogenase activity
EB230_RS10850	COG1305	Transglutaminase-like
EB230_RS10855	COG1215	transferase activity, transferring glycosyl groups
EB230_RS10865	COG3795	YCII-related domain
EB230_RS10870	COG4941	Belongs to the sigma-70 factor family
EB230_RS10875	COG1012	belongs to the aldehyde dehydrogenase family
EB230_RS10900	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS10905	COG1012	belongs to the aldehyde dehydrogenase family
EB230_RS10960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EB230_RS10965	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS10970	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EB230_RS10975	COG1309	transcriptional regulator
EB230_RS10995	COG0673	inositol 2-dehydrogenase activity
EB230_RS11000	COG0482	sulfurtransferase activity
EB230_RS11015	COG1733	regulation of RNA biosynthetic process
EB230_RS11030	COG2201	protein-glutamate methylesterase activity
EB230_RS11050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EB230_RS11075	COG0435	Glutathione S-transferase
EB230_RS11080	COG1051	belongs to the nudix hydrolase family
EB230_RS11095	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB230_RS11095	COG0596	Alpha beta hydrolase
EB230_RS11105	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EB230_RS11135	COG1335	isochorismatase
EB230_RS11150	COG3180	Ammonia monooxygenase
EB230_RS11160	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS11175	COG4456	Virulence-associated protein
EB230_RS11180	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EB230_RS11185	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EB230_RS11185	COG0512	Glutamine amidotransferase of anthranilate synthase
EB230_RS11190	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EB230_RS11200	COG2814	Major facilitator Superfamily
EB230_RS11205	COG4993	Dehydrogenase
EB230_RS11215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EB230_RS11240	COG1335	isochorismatase
EB230_RS11245	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EB230_RS11280	COG0583	DNA-binding transcription factor activity
EB230_RS11285	COG0697	spore germination
EB230_RS11290	COG1435	thymidine kinase activity
EB230_RS11300	COG4176	ABC-type proline glycine betaine transport system permease component
EB230_RS11310	COG2205	protein histidine kinase activity
EB230_RS11315	COG0745	RESPONSE REGULATOR receiver
EB230_RS11335	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EB230_RS11355	COG0714	Associated with various cellular activities
EB230_RS11365	COG0494	nUDIX hydrolase
EB230_RS11370	COG0617	tRNA 3'-terminal CCA addition
EB230_RS11380	COG0408	coproporphyrinogen oxidase activity
EB230_RS11390	COG0789	Transcriptional regulator
EB230_RS11395	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EB230_RS11405	COG1132	(ABC) transporter
EB230_RS11410	COG1132	(ABC) transporter
EB230_RS11440	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EB230_RS11440	COG2857	Cytochrome c1
EB230_RS11445	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EB230_RS11470	COG2233	PERMEase
EB230_RS11475	COG0402	S-adenosylhomocysteine deaminase activity
EB230_RS11485	COG0012	GTP binding
EB230_RS11490	COG0193	aminoacyl-tRNA hydrolase activity
EB230_RS11495	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EB230_RS11500	COG1846	Transcriptional regulator
EB230_RS11510	COG2223	nitrite transmembrane transporter activity
EB230_RS11515	COG2207	Transcriptional regulator
EB230_RS11525	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EB230_RS11550	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EB230_RS11570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EB230_RS11580	COG2205	protein histidine kinase activity
EB230_RS11585	COG0745	RESPONSE REGULATOR receiver
EB230_RS11590	COG1846	Transcriptional regulator
EB230_RS11595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EB230_RS11605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EB230_RS11615	COG1278	Cold shock
EB230_RS11620	COG1278	Cold shock
EB230_RS11655	COG1278	Cold shock
EB230_RS11665	COG0457	Tetratricopeptide repeat
EB230_RS11670	COG5507	3-demethylubiquinone-9 3-methyltransferase
EB230_RS11690	COG0488	(ABC) transporter
EB230_RS11695	COG0556	nucleotide-excision repair
EB230_RS11705	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EB230_RS11725	COG0583	DNA-binding transcription factor activity
EB230_RS11730	COG2175	clavaminate synthase activity
EB230_RS11760	COG0277	FAD linked oxidase domain protein
EB230_RS11775	COG2267	carboxylic ester hydrolase activity
EB230_RS11790	COG1597	lipid kinase activity
EB230_RS11800	COG4948	Mandelate Racemase Muconate Lactonizing
EB230_RS11810	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EB230_RS11815	COG1607	acyl-coa hydrolase
EB230_RS11840	COG1733	regulation of RNA biosynthetic process
EB230_RS11865	COG4941	Belongs to the sigma-70 factor family
EB230_RS11870	COG3795	YCII-related domain
EB230_RS11880	COG1253	flavin adenine dinucleotide binding
EB230_RS11920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EB230_RS11925	COG0859	PFAM glycosyl transferase family 9
EB230_RS11935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EB230_RS11945	COG1280	lysine exporter protein (LysE YggA)
EB230_RS11950	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EB230_RS11950	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EB230_RS11955	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EB230_RS11960	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EB230_RS11965	COG0463	Glycosyl transferase, family 2
EB230_RS11970	COG1522	sequence-specific DNA binding
EB230_RS11975	COG0492	ferredoxin-NADP+ reductase activity
EB230_RS11980	COG0583	DNA-binding transcription factor activity
EB230_RS11990	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EB230_RS11995	COG3300	MHYT domain
EB230_RS11995	COG5001	Diguanylate cyclase
EB230_RS12005	COG0436	Aminotransferase
EB230_RS12015	COG3300	MHYT domain
EB230_RS12015	COG5001	Diguanylate cyclase
EB230_RS12020	COG0625	glutathione transferase activity
EB230_RS12030	COG1278	Cold shock
EB230_RS12040	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EB230_RS12075	COG1295	ribonuclease BN
EB230_RS12090	COG0251	oxidation-reduction process
EB230_RS12105	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EB230_RS12130	COG2814	Major facilitator Superfamily
EB230_RS12140	COG4221	oxidoreductase activity
EB230_RS12150	COG0583	DNA-binding transcription factor activity
EB230_RS12160	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EB230_RS12165	COG1914	H( )-stimulated, divalent metal cation uptake system
EB230_RS12170	COG1321	iron dependent repressor
EB230_RS12180	COG2321	neutral zinc metallopeptidase
EB230_RS12190	COG4989	oxidoreductase activity
EB230_RS12195	COG0505	Belongs to the CarA family
EB230_RS12200	COG1610	YqeY-like protein
EB230_RS12215	COG0300	oxidoreductase activity
EB230_RS12220	COG0305	Participates in initiation and elongation during chromosome replication
EB230_RS12240	COG0765	amino acid transport
EB230_RS12245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB230_RS12255	COG0583	DNA-binding transcription factor activity
EB230_RS12265	COG0789	Transcriptional regulator
EB230_RS12275	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS12280	COG0583	DNA-binding transcription factor activity
EB230_RS12285	COG2814	Major facilitator Superfamily
EB230_RS12310	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EB230_RS12340	COG1695	Transcriptional regulator
EB230_RS12365	COG4988	ABC transporter
EB230_RS12370	COG4988	ABC transporter
EB230_RS12375	COG1271	oxidase subunit
EB230_RS12380	COG1294	oxidase, subunit
EB230_RS12405	COG4948	Mandelate Racemase Muconate Lactonizing
EB230_RS12420	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS12435	COG0673	inositol 2-dehydrogenase activity
EB230_RS12445	COG2223	nitrite transmembrane transporter activity
EB230_RS12450	COG1522	sequence-specific DNA binding
EB230_RS12465	COG3842	ATPase activity
EB230_RS12470	COG3246	L-lysine catabolic process to acetate
EB230_RS12480	COG1175	transmembrane transport
EB230_RS12500	COG1940	carbohydrate kinase activity
EB230_RS12505	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EB230_RS12515	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EB230_RS12535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EB230_RS12540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EB230_RS12545	COG2197	response regulator
EB230_RS12550	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS12555	COG2862	Uncharacterized protein family, UPF0114
EB230_RS12565	COG2983	Belongs to the UPF0260 family
EB230_RS12575	COG2968	Membrane
EB230_RS12585	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EB230_RS12640	COG3118	belongs to the thioredoxin family
EB230_RS12645	COG2217	Heavy metal translocating P-type atpase
EB230_RS12650	COG0045	succinate-CoA ligase (ADP-forming) activity
EB230_RS12650	COG1042	CoA-binding domain protein
EB230_RS12650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EB230_RS12690	COG0156	8-amino-7-oxononanoate synthase activity
EB230_RS12715	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB230_RS12715	COG0022	dehydrogenase e1 component
EB230_RS12725	COG4566	intracellular signal transduction
EB230_RS12730	COG4191	Histidine kinase
EB230_RS12760	COG0517	IMP dehydrogenase activity
EB230_RS12760	COG0617	tRNA 3'-terminal CCA addition
EB230_RS12760	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EB230_RS12780	COG0745	RESPONSE REGULATOR receiver
EB230_RS12785	COG2205	protein histidine kinase activity
EB230_RS12815	COG3794	PFAM blue (type 1) copper domain protein
EB230_RS12860	COG2010	Cytochrome c
EB230_RS12890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EB230_RS12925	COG0583	DNA-binding transcription factor activity
EB230_RS12930	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS12935	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS12965	COG0459	protein refolding
EB230_RS12970	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EB230_RS12980	COG5425	PFAM Usg family protein
EB230_RS12995	COG0071	Belongs to the small heat shock protein (HSP20) family
EB230_RS13000	COG0071	Belongs to the small heat shock protein (HSP20) family
EB230_RS13010	COG2423	ornithine cyclodeaminase activity
EB230_RS13015	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EB230_RS13020	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB230_RS13020	COG1902	pentaerythritol trinitrate reductase activity
EB230_RS13025	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EB230_RS13035	COG4166	transmembrane transport
EB230_RS13040	COG0601	transmembrane transport
EB230_RS13055	COG0251	oxidation-reduction process
EB230_RS13060	COG4172	Belongs to the ABC transporter superfamily
EB230_RS13065	COG4172	Belongs to the ABC transporter superfamily
EB230_RS13070	COG0583	DNA-binding transcription factor activity
EB230_RS13080	COG0601	transmembrane transport
EB230_RS13085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB230_RS13110	COG4608	Belongs to the ABC transporter superfamily
EB230_RS13115	COG0444	Belongs to the ABC transporter superfamily
EB230_RS13120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB230_RS13125	COG0601	transmembrane transport
EB230_RS13130	COG0747	negative chemotaxis
EB230_RS13135	COG1396	sequence-specific DNA binding
EB230_RS13145	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EB230_RS13155	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS13165	COG2376	Dihydroxyacetone kinase
EB230_RS13170	COG2376	Dihydroxyacetone kinase
EB230_RS13190	COG1175	transmembrane transport
EB230_RS13195	COG0395	ABC-type sugar transport system, permease component
EB230_RS13205	COG1349	DNA-binding transcription factor activity
EB230_RS13215	COG0583	DNA-binding transcription factor activity
EB230_RS13220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EB230_RS13235	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
EB230_RS13250	COG0583	DNA-binding transcription factor activity
EB230_RS13255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB230_RS13265	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB230_RS13265	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB230_RS13275	COG0436	Aminotransferase
EB230_RS13300	COG4608	Belongs to the ABC transporter superfamily
EB230_RS13315	COG5598	trimethylamine methyltransferase
EB230_RS13330	COG1454	alcohol dehydrogenase
EB230_RS13335	COG3485	protocatechuate 3,4-dioxygenase
EB230_RS13345	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS13355	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS13370	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS13390	COG0473	3-isopropylmalate dehydrogenase activity
EB230_RS13400	COG1012	belongs to the aldehyde dehydrogenase family
EB230_RS13410	COG1129	ABC transporter
EB230_RS13440	COG0242	peptide deformylase activity
EB230_RS13445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB230_RS13460	COG0154	amidase activity
EB230_RS13475	COG3454	Phosphonate metabolism
EB230_RS13480	COG4221	oxidoreductase activity
EB230_RS13485	COG1595	DNA-templated transcription, initiation
EB230_RS13495	COG3300	MHYT domain
EB230_RS13495	COG5001	Diguanylate cyclase
EB230_RS13500	COG1473	amidohydrolase
EB230_RS13525	COG2080	2 iron, 2 sulfur cluster binding
EB230_RS13525	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EB230_RS13575	COG2890	protein-(glutamine-N5) methyltransferase activity
EB230_RS13585	COG0318	PFAM AMP-dependent synthetase and ligase
EB230_RS13590	COG0367	asparagine synthase
EB230_RS13595	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EB230_RS13600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EB230_RS13600	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EB230_RS13620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB230_RS13640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB230_RS13645	COG0784	Response regulator, receiver
EB230_RS13645	COG4191	Histidine kinase
EB230_RS13660	COG0475	glutathione-regulated potassium exporter activity
EB230_RS13675	COG2814	Major facilitator Superfamily
EB230_RS13680	COG0583	DNA-binding transcription factor activity
EB230_RS13685	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EB230_RS13690	COG3608	succinylglutamate desuccinylase aspartoacylase
EB230_RS13695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB230_RS13705	COG0765	amino acid transport
EB230_RS13725	COG0251	oxidation-reduction process
EB230_RS13735	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EB230_RS13740	COG1869	D-ribose catabolic process
EB230_RS13760	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS13790	COG0346	lactoylglutathione lyase activity
EB230_RS13815	COG5002	protein histidine kinase activity
EB230_RS13815	COG5001	Diguanylate cyclase
EB230_RS13845	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EB230_RS13850	COG0459	protein refolding
EB230_RS13865	COG1956	GAF domain-containing protein
EB230_RS13875	COG2855	membrane
EB230_RS13905	COG0667	Aldo Keto reductase
EB230_RS13910	COG4221	oxidoreductase activity
EB230_RS13915	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EB230_RS13945	COG1902	pentaerythritol trinitrate reductase activity
EB230_RS13975	COG0406	alpha-ribazole phosphatase activity
EB230_RS14045	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB230_RS14050	COG0640	Transcriptional regulator
EB230_RS14055	COG0667	Aldo Keto reductase
EB230_RS14060	COG0583	DNA-binding transcription factor activity
EB230_RS14070	COG0392	lysyltransferase activity
EB230_RS14070	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EB230_RS14080	COG5001	Diguanylate cyclase
EB230_RS14080	COG4251	negative regulation of phosphorylation
EB230_RS14080	COG3706	GGDEF domain
EB230_RS14080	COG2203	Gaf domain
EB230_RS14090	COG0798	PFAM Bile acid sodium symporter
EB230_RS14105	COG0492	ferredoxin-NADP+ reductase activity
EB230_RS14115	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EB230_RS14125	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EB230_RS14130	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EB230_RS14175	COG1129	ABC transporter
EB230_RS14180	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS14225	COG3756	Protein conserved in bacteria
EB230_RS14245	COG0596	Alpha beta hydrolase
EB230_RS14260	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS14300	COG2755	lipolytic protein G-D-S-L family
EB230_RS14300	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EB230_RS14345	COG0753	catalase activity
EB230_RS14355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EB230_RS14375	COG3206	protein involved in exopolysaccharide biosynthesis
EB230_RS14375	COG0489	protein tyrosine kinase activity
EB230_RS14395	COG0297	glycogen (starch) synthase activity
EB230_RS14430	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EB230_RS14480	COG0625	glutathione transferase activity
EB230_RS14485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EB230_RS14490	COG0583	DNA-binding transcription factor activity
EB230_RS14515	COG0625	glutathione transferase activity
EB230_RS14520	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS14545	COG0488	(ABC) transporter
EB230_RS14570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EB230_RS14575	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EB230_RS14585	COG4977	sequence-specific DNA binding
EB230_RS14585	COG1917	Cupin 2, conserved barrel domain protein
EB230_RS14590	COG3842	ATPase activity
EB230_RS14600	COG1177	transmembrane transport
EB230_RS14605	COG4149	molybdate abc transporter
EB230_RS14625	COG0326	Molecular chaperone. Has ATPase activity
EB230_RS14660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EB230_RS14665	COG0583	DNA-binding transcription factor activity
EB230_RS14670	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS14675	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS14685	COG0583	DNA-binding transcription factor activity
EB230_RS14780	COG0850	regulation of cytokinetic process
EB230_RS14785	COG2894	cell division
EB230_RS14790	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EB230_RS14795	COG2205	protein histidine kinase activity
EB230_RS14800	COG0745	RESPONSE REGULATOR receiver
EB230_RS14815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB230_RS14820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EB230_RS14830	COG2197	response regulator
EB230_RS14840	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
EB230_RS14845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB230_RS14855	COG5006	permease, DMT superfamily
EB230_RS14865	COG1030	water channel activity
EB230_RS14870	COG0330	HflC and HflK could
EB230_RS14875	COG0583	DNA-binding transcription factor activity
EB230_RS14885	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EB230_RS14890	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EB230_RS14895	COG2080	2 iron, 2 sulfur cluster binding
EB230_RS14900	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EB230_RS14905	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EB230_RS14910	COG2080	2 iron, 2 sulfur cluster binding
EB230_RS14915	COG1309	transcriptional regulator
EB230_RS14930	COG1063	alcohol dehydrogenase
EB230_RS14955	COG0656	L-ascorbic acid biosynthetic process
EB230_RS14990	COG0596	Alpha beta hydrolase
EB230_RS15000	COG0415	Belongs to the DNA photolyase family
EB230_RS15015	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS15020	COG1129	ABC transporter
EB230_RS15030	COG1082	Xylose isomerase domain protein TIM barrel
EB230_RS15035	COG0246	Mannitol dehydrogenase
EB230_RS15040	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS15050	COG0673	inositol 2-dehydrogenase activity
EB230_RS15065	COG1162	GTPase activity
EB230_RS15080	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EB230_RS15115	COG0596	Alpha beta hydrolase
EB230_RS15130	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EB230_RS15130	COG2169	Transcriptional regulator
EB230_RS15140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EB230_RS15140	COG2169	Transcriptional regulator
EB230_RS15145	COG1733	regulation of RNA biosynthetic process
EB230_RS15175	COG5001	Diguanylate cyclase
EB230_RS15175	COG5002	protein histidine kinase activity
EB230_RS15205	COG0747	negative chemotaxis
EB230_RS15220	COG0583	DNA-binding transcription factor activity
EB230_RS15225	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS15230	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EB230_RS15270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB230_RS15295	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EB230_RS15315	COG1181	Belongs to the D-alanine--D-alanine ligase family
EB230_RS15320	COG1396	sequence-specific DNA binding
EB230_RS15325	COG0300	oxidoreductase activity
EB230_RS15330	COG4221	oxidoreductase activity
EB230_RS15340	COG0628	permease
EB230_RS15355	COG1335	isochorismatase
EB230_RS15390	COG0667	Aldo Keto reductase
EB230_RS15405	COG4191	Histidine kinase
EB230_RS15475	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EB230_RS15535	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EB230_RS15540	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EB230_RS15555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB230_RS15595	COG3920	Histidine kinase
EB230_RS15615	COG1397	ADP-ribosylglycohydrolase
EB230_RS15620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB230_RS15625	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EB230_RS15635	COG1177	transmembrane transport
EB230_RS15640	COG3842	ATPase activity
EB230_RS15665	COG4558	Periplasmic binding protein
EB230_RS15675	COG1053	succinate dehydrogenase
EB230_RS15695	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EB230_RS15700	COG1609	Transcriptional regulator
EB230_RS15710	COG0395	ABC-type sugar transport system, permease component
EB230_RS15715	COG1175	transmembrane transport
EB230_RS15720	COG3842	ATPase activity
EB230_RS15745	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS15770	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EB230_RS15775	COG2986	histidine ammonia-lyase
EB230_RS15785	COG0477	Major facilitator Superfamily
EB230_RS15790	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS15810	COG1129	ABC transporter
EB230_RS15830	COG1175	transmembrane transport
EB230_RS15855	COG0542	response to heat
EB230_RS15865	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EB230_RS15885	COG2169	Transcriptional regulator
EB230_RS15885	COG1917	Cupin 2, conserved barrel domain protein
EB230_RS15890	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS15895	COG1129	ABC transporter
EB230_RS15905	COG2186	Transcriptional regulator
EB230_RS15915	COG1086	Polysaccharide biosynthesis protein
EB230_RS15930	COG2271	Major facilitator Superfamily
EB230_RS15935	COG1609	Transcriptional regulator
EB230_RS15945	COG1129	ABC transporter
EB230_RS15950	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS15955	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS15960	COG3265	gluconokinase activity
EB230_RS15970	COG1959	2 iron, 2 sulfur cluster binding
EB230_RS15975	COG4150	thiosulfate binding
EB230_RS15990	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EB230_RS15995	COG4208	sulfate ABC transporter
EB230_RS16000	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EB230_RS16005	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EB230_RS16015	COG4953	penicillin-binding protein 1C
EB230_RS16020	COG2373	Large extracellular alpha-helical protein
EB230_RS16040	COG0601	transmembrane transport
EB230_RS16045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB230_RS16060	COG5598	trimethylamine methyltransferase
EB230_RS16085	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EB230_RS16090	COG0493	'glutamate synthase
EB230_RS16110	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EB230_RS16115	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS16120	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS16130	COG1309	transcriptional regulator
EB230_RS16170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB230_RS16175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB230_RS16180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EB230_RS16185	COG1522	sequence-specific DNA binding
EB230_RS16200	COG0028	Belongs to the TPP enzyme family
EB230_RS16205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EB230_RS16220	COG3706	GGDEF domain
EB230_RS16230	COG4106	trans-aconitate 2-methyltransferase activity
EB230_RS16255	COG2020	methyltransferase activity
EB230_RS16270	COG1309	transcriptional regulator
EB230_RS16280	COG0300	oxidoreductase activity
EB230_RS16285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EB230_RS16300	COG1720	tRNA m6t6A37 methyltransferase activity
EB230_RS16360	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EB230_RS16365	COG3023	N-Acetylmuramoyl-L-alanine amidase
EB230_RS16390	COG0626	cystathionine gamma-synthase activity
EB230_RS16395	COG2001	Belongs to the MraZ family
EB230_RS16400	COG0275	rRNA processing
EB230_RS16415	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EB230_RS16425	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EB230_RS16430	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EB230_RS16440	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EB230_RS16445	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EB230_RS16450	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EB230_RS16455	COG1181	Belongs to the D-alanine--D-alanine ligase family
EB230_RS16460	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EB230_RS16465	COG0849	cell division
EB230_RS16470	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EB230_RS16480	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EB230_RS16490	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EB230_RS16510	COG0006	proline dipeptidase activity
EB230_RS16520	COG2264	protein methyltransferase activity
EB230_RS16525	COG1999	signal sequence binding
EB230_RS16545	COG0300	oxidoreductase activity
EB230_RS16565	COG0534	Mate efflux family protein
EB230_RS16585	COG5598	trimethylamine methyltransferase
EB230_RS16590	COG1116	anion transmembrane transporter activity
EB230_RS16605	COG4566	intracellular signal transduction
EB230_RS16610	COG4191	Histidine kinase
EB230_RS16625	COG0210	DNA helicase
EB230_RS16650	COG0784	Response regulator, receiver
EB230_RS16655	COG0784	Response regulator, receiver
EB230_RS16655	COG4191	Histidine kinase
EB230_RS16665	COG1522	sequence-specific DNA binding
EB230_RS16680	COG0277	FAD linked oxidase domain protein
EB230_RS16690	COG2837	iron assimilation
EB230_RS16740	COG2814	Major facilitator Superfamily
EB230_RS16760	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EB230_RS16770	COG3585	molybdate ion transport
EB230_RS16775	COG0725	ABC transporter, periplasmic molybdate-binding protein
EB230_RS16780	COG4149	molybdate abc transporter
EB230_RS16785	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EB230_RS16790	COG3585	molybdate ion transport
EB230_RS16790	COG2005	Transcriptional regulator
EB230_RS16815	COG0330	HflC and HflK could
EB230_RS16835	COG3830	Belongs to the UPF0237 family
EB230_RS16835	COG0560	Phosphoserine phosphatase
EB230_RS16840	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EB230_RS16845	COG2203	Gaf domain
EB230_RS16845	COG2199	diguanylate cyclase activity
EB230_RS16855	COG1396	sequence-specific DNA binding
EB230_RS16875	COG2175	clavaminate synthase activity
EB230_RS16890	COG1063	alcohol dehydrogenase
EB230_RS16895	COG3284	Transcriptional regulator
EB230_RS16900	COG0028	Belongs to the TPP enzyme family
EB230_RS16910	COG0640	Transcriptional regulator
EB230_RS16925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB230_RS16950	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EB230_RS16960	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EB230_RS16965	COG3158	transport of potassium into the cell
EB230_RS16970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EB230_RS16980	COG1733	regulation of RNA biosynthetic process
EB230_RS16985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EB230_RS17005	COG1309	transcriptional regulator
EB230_RS17010	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EB230_RS17035	COG1136	(ABC) transporter
EB230_RS17035	COG0577	efflux transmembrane transporter activity
EB230_RS17040	COG1136	(ABC) transporter
EB230_RS17040	COG0577	efflux transmembrane transporter activity
EB230_RS17050	COG0384	phenazine biosynthesis protein PhzF
EB230_RS17130	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EB230_RS17140	COG1061	Type III restriction enzyme res subunit
EB230_RS17290	COG0438	transferase activity, transferring glycosyl groups
EB230_RS17485	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EB230_RS17490	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EB230_RS17495	COG1797	cobyrinic acid a,c-diamide synthase activity
EB230_RS17560	COG3214	Protein conserved in bacteria
EB230_RS17570	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EB230_RS17575	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EB230_RS17580	COG0649	NAD binding
EB230_RS17585	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EB230_RS17590	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EB230_RS17595	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EB230_RS17595	COG3743	rRNA binding
EB230_RS17605	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EB230_RS17610	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EB230_RS17620	COG0713	ATP synthesis coupled electron transport
EB230_RS17635	COG1007	ATP synthesis coupled electron transport
EB230_RS17650	COG0346	lactoylglutathione lyase activity
EB230_RS17660	COG0442	prolyl-tRNA aminoacylation
EB230_RS17670	COG1136	(ABC) transporter
EB230_RS17680	COG0321	lipoyl(octanoyl) transferase activity
EB230_RS17690	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EB230_RS17695	COG0045	succinate-CoA ligase (ADP-forming) activity
EB230_RS17700	COG2301	Belongs to the HpcH HpaI aldolase family
EB230_RS17715	COG2239	Acts as a magnesium transporter
EB230_RS17785	COG3609	addiction module antidote protein, CC2985 family
EB230_RS17795	COG0251	oxidation-reduction process
EB230_RS17810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB230_RS17815	COG0402	S-adenosylhomocysteine deaminase activity
EB230_RS17825	COG2249	NAD(P)H dehydrogenase (quinone) activity
EB230_RS17830	COG2249	NAD(P)H dehydrogenase (quinone) activity
EB230_RS17845	COG2040	homocysteine
EB230_RS17865	COG2814	Major facilitator Superfamily
EB230_RS17870	COG0583	DNA-binding transcription factor activity
EB230_RS17890	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB230_RS17890	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB230_RS17900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB230_RS17905	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EB230_RS17905	COG3264	Mechanosensitive ion channel
EB230_RS17915	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EB230_RS17930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EB230_RS17970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB230_RS17990	COG0583	DNA-binding transcription factor activity
EB230_RS18015	COG1410	methionine synthase
EB230_RS18015	COG0646	methionine synthase
EB230_RS18045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EB230_RS18060	COG5012	cobalamin binding
EB230_RS18075	COG2186	Transcriptional regulator
EB230_RS18080	COG2807	transmembrane transport
EB230_RS18100	COG2304	oxidoreductase activity
EB230_RS18105	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EB230_RS18105	COG0519	Catalyzes the synthesis of GMP from XMP
EB230_RS18115	COG1410	methionine synthase
EB230_RS18115	COG0646	methionine synthase
EB230_RS18120	COG3665	Urea carboxylase-associated protein
EB230_RS18140	COG0006	proline dipeptidase activity
EB230_RS18165	COG1505	serine-type exopeptidase activity
EB230_RS18190	COG1960	acyl-CoA dehydrogenase activity
EB230_RS18200	COG1492	cobalamin metabolic process
EB230_RS18230	COG4172	Belongs to the ABC transporter superfamily
EB230_RS18240	COG0601	transmembrane transport
EB230_RS18245	COG0747	negative chemotaxis
EB230_RS18250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB230_RS18270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EB230_RS18275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EB230_RS18280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EB230_RS18320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB230_RS18330	COG1858	cytochrome C peroxidase
EB230_RS18335	COG1522	sequence-specific DNA binding
EB230_RS18370	COG3720	iron ion transport
EB230_RS18375	COG4558	Periplasmic binding protein
EB230_RS18380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EB230_RS18385	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EB230_RS18390	COG1959	2 iron, 2 sulfur cluster binding
EB230_RS18395	COG2733	membrane
EB230_RS18425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB230_RS18430	COG0697	spore germination
EB230_RS18445	COG2814	Major facilitator Superfamily
EB230_RS18465	COG5002	protein histidine kinase activity
EB230_RS18510	COG3142	Participates in the control of copper homeostasis
EB230_RS18525	COG1733	regulation of RNA biosynthetic process
EB230_RS18530	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS18555	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EB230_RS18575	COG0525	valine-tRNA ligase activity
EB230_RS18590	COG0129	dihydroxy-acid dehydratase activity
EB230_RS18605	COG1595	DNA-templated transcription, initiation
EB230_RS18630	COG0708	Exodeoxyribonuclease III
EB230_RS18645	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EB230_RS18650	COG0018	arginyl-trna synthetase
EB230_RS18665	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EB230_RS18670	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EB230_RS18675	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EB230_RS18680	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EB230_RS18685	COG0805	protein transport
EB230_RS18690	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EB230_RS18695	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EB230_RS18700	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EB230_RS18725	COG1862	Preprotein translocase
EB230_RS18765	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EB230_RS18795	COG0544	peptidyl-prolyl cis-trans isomerase activity
EB230_RS18810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB230_RS18815	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS18820	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS18825	COG1879	ABC-type sugar transport system periplasmic component
EB230_RS18840	COG1609	Transcriptional regulator
EB230_RS18855	COG2003	Belongs to the UPF0758 family
EB230_RS18860	COG0024	Methionine aminopeptidase
EB230_RS18915	COG3243	poly(R)-hydroxyalkanoic acid synthase
EB230_RS18925	COG0436	Aminotransferase
EB230_RS18945	COG1494	fructose-1,6-bisphosphatase
EB230_RS18955	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EB230_RS18960	COG1752	Esterase of the alpha-beta hydrolase superfamily
EB230_RS18965	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EB230_RS18970	COG0302	gtp cyclohydrolase
EB230_RS18980	COG0583	DNA-binding transcription factor activity
EB230_RS18990	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EB230_RS19000	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EB230_RS19030	COG2030	dehydratase
EB230_RS19045	COG0187	DNA topoisomerase II activity
EB230_RS19055	COG4964	Belongs to the GSP D family
EB230_RS19095	COG3706	GGDEF domain
EB230_RS19100	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EB230_RS19100	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EB230_RS19105	COG0509	glycine decarboxylation via glycine cleavage system
EB230_RS19110	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB230_RS19125	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EB230_RS19140	COG1671	Belongs to the UPF0178 family
EB230_RS19145	COG3791	Glutathione-dependent formaldehyde-activating
EB230_RS19150	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EB230_RS19155	COG4770	biotin carboxylase activity
EB230_RS19165	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EB230_RS19180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EB230_RS19205	COG0784	Response regulator, receiver
EB230_RS19215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EB230_RS19220	COG4977	sequence-specific DNA binding
EB230_RS19230	COG2186	Transcriptional regulator
EB230_RS19235	COG0626	cystathionine gamma-synthase activity
EB230_RS19250	COG0395	ABC-type sugar transport system, permease component
EB230_RS19255	COG3842	ATPase activity
EB230_RS19260	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EB230_RS19285	COG0557	exoribonuclease II activity
EB230_RS19290	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EB230_RS19300	COG0785	Cytochrome C biogenesis protein
EB230_RS19305	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EB230_RS19310	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EB230_RS19320	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EB230_RS19330	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EB230_RS19335	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EB230_RS19345	COG3706	GGDEF domain
EB230_RS19355	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EB230_RS19390	COG5265	(ABC) transporter
EB230_RS19400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EB230_RS19410	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EB230_RS19415	COG0281	malic enzyme
EB230_RS19415	COG0280	phosphate acetyltransferase
EB230_RS19435	COG4948	Mandelate Racemase Muconate Lactonizing
EB230_RS19445	COG1127	ABC transporter
EB230_RS19475	COG0633	Ferredoxin
EB230_RS19480	COG0492	ferredoxin-NADP+ reductase activity
EB230_RS19485	COG2814	Major facilitator Superfamily
EB230_RS19495	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EB230_RS19500	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EB230_RS19505	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EB230_RS19515	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EB230_RS19515	COG0475	glutathione-regulated potassium exporter activity
EB230_RS19530	COG3768	UPF0283 membrane protein
EB230_RS19535	COG3106	COG3106 Predicted ATPase
EB230_RS19560	COG0813	purine-nucleoside phosphorylase activity
EB230_RS19645	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EB230_RS19655	COG0740	serine-type endopeptidase activity
EB230_RS19670	COG0629	single-stranded DNA binding
EB230_RS19675	COG1765	OsmC-like protein
EB230_RS19680	COG2095	MarC family integral membrane protein
EB230_RS19695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EB230_RS19695	COG2169	Transcriptional regulator
EB230_RS19710	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EB230_RS19720	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EB230_RS19740	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EB230_RS19750	COG0343	queuine tRNA-ribosyltransferase activity
EB230_RS19765	COG2308	Evidence 4 Homologs of previously reported genes of
EB230_RS19815	COG0395	ABC-type sugar transport system, permease component
EB230_RS19830	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EB230_RS19855	COG0438	transferase activity, transferring glycosyl groups
EB230_RS19880	COG0758	DNA mediated transformation
EB230_RS19885	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EB230_RS19890	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EB230_RS19895	COG0540	Belongs to the ATCase OTCase family
EB230_RS19900	COG1960	acyl-CoA dehydrogenase activity
EB230_RS19915	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EB230_RS19920	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EB230_RS19930	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EB230_RS19940	COG0154	amidase activity
EB230_RS19945	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EB230_RS19955	COG1760	l-serine dehydratase
EB230_RS19965	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EB230_RS19970	COG1686	Belongs to the peptidase S11 family
EB230_RS19980	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EB230_RS20000	COG0537	adenosine 5'-monophosphoramidase activity
EB230_RS20035	COG0052	Belongs to the universal ribosomal protein uS2 family
EB230_RS20040	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EB230_RS20045	COG0583	DNA-binding transcription factor activity
EB230_RS20055	COG0667	Aldo Keto reductase
EB230_RS20060	COG0528	UMP kinase activity
EB230_RS20065	COG0233	cytoplasmic translational termination
EB230_RS20070	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EB230_RS20080	COG0750	zinc metalloprotease
EB230_RS20085	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EB230_RS20090	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EB230_RS20095	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EB230_RS20100	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EB230_RS20105	COG3494	Protein of unknown function (DUF1009)
EB230_RS20110	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EB230_RS20115	COG0372	Belongs to the citrate synthase family
EB230_RS20120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EB230_RS20130	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EB230_RS20135	COG1802	Transcriptional regulator
EB230_RS20145	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EB230_RS20150	COG4120	Belongs to the binding-protein-dependent transport system permease family
EB230_RS20160	COG3483	tryptophan 2,3-dioxygenase activity
EB230_RS20175	COG0303	'Molybdopterin
EB230_RS20180	COG0315	cyclic pyranopterin monophosphate synthase activity
EB230_RS20185	COG0134	indole-3-glycerol-phosphate synthase activity
EB230_RS20190	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EB230_RS20195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EB230_RS20200	COG0149	triose-phosphate isomerase activity
EB230_RS20215	COG0504	CTP synthase activity
EB230_RS20225	COG1953	Uracil, thiamine, allantoin
EB230_RS20230	COG0583	DNA-binding transcription factor activity
EB230_RS20235	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EB230_RS20240	COG2267	carboxylic ester hydrolase activity
EB230_RS20245	COG0747	negative chemotaxis
EB230_RS20250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB230_RS20260	COG0444	Belongs to the ABC transporter superfamily
EB230_RS20265	COG4608	Belongs to the ABC transporter superfamily
EB230_RS20280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EB230_RS20310	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS20315	COG0235	Class ii aldolase
EB230_RS20325	COG1129	ABC transporter
EB230_RS20330	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS20335	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS20345	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS20350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EB230_RS20365	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EB230_RS20370	COG2202	Pas domain
EB230_RS20370	COG2205	protein histidine kinase activity
EB230_RS20375	COG1525	nuclease
EB230_RS20385	COG1573	uracil-dna glycosylase
EB230_RS20390	COG1522	sequence-specific DNA binding
EB230_RS20410	COG2084	Dehydrogenase
EB230_RS20425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB230_RS20430	COG1763	Mo-molybdopterin cofactor biosynthetic process
EB230_RS20435	COG0746	molybdenum cofactor guanylyltransferase activity
EB230_RS20455	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EB230_RS20470	COG1846	Transcriptional regulator
EB230_RS20485	COG1309	transcriptional regulator
EB230_RS20490	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS20515	COG0546	phosphoglycolate phosphatase activity
EB230_RS20520	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EB230_RS20535	COG2239	Acts as a magnesium transporter
EB230_RS20540	COG4178	(ABC) transporter
EB230_RS20550	COG4166	transmembrane transport
EB230_RS20565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EB230_RS20580	COG1183	phosphatidylcholine synthase activity
EB230_RS20610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EB230_RS20615	COG0861	Integral membrane protein TerC family
EB230_RS20630	COG0596	Alpha beta hydrolase
EB230_RS20775	COG2135	peptidase activity
EB230_RS20850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB230_RS20855	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
EB230_RS20890	COG1686	Belongs to the peptidase S11 family
EB230_RS20895	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EB230_RS20905	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EB230_RS20910	COG0084	hydrolase, TatD family'
EB230_RS20935	COG0670	Belongs to the BI1 family
EB230_RS20960	COG3956	TIGRFAM MazG family protein
EB230_RS20965	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EB230_RS20970	COG1923	regulation of RNA biosynthetic process
EB230_RS20975	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EB230_RS20980	COG2204	response regulator
EB230_RS20985	COG5000	phosphorelay sensor kinase activity
EB230_RS20990	COG2204	response regulator
EB230_RS20995	COG3852	Histidine kinase
EB230_RS21005	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EB230_RS21005	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EB230_RS21020	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EB230_RS21030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EB230_RS21045	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB230_RS21045	COG0022	dehydrogenase e1 component
EB230_RS21050	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EB230_RS21055	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EB230_RS21060	COG0148	phosphopyruvate hydratase activity
EB230_RS21075	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EB230_RS21095	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EB230_RS21105	COG0737	Belongs to the 5'-nucleotidase family
EB230_RS21110	COG1252	NADH dehydrogenase
EB230_RS21115	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EB230_RS21120	COG1522	sequence-specific DNA binding
EB230_RS21125	COG0686	Belongs to the AlaDH PNT family
EB230_RS21150	COG2897	thiosulfate sulfurtransferase activity
EB230_RS21155	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EB230_RS21165	COG0300	oxidoreductase activity
EB230_RS21175	COG0513	Belongs to the DEAD box helicase family
EB230_RS21190	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EB230_RS21200	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EB230_RS21200	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EB230_RS21205	COG0347	Belongs to the P(II) protein family
EB230_RS21210	COG0174	glutamine synthetase
EB230_RS21215	COG0174	glutamine synthetase
EB230_RS21235	COG0697	spore germination
EB230_RS21245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EB230_RS21255	COG1012	belongs to the aldehyde dehydrogenase family
EB230_RS21260	COG3284	Transcriptional regulator
EB230_RS21275	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EB230_RS21280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EB230_RS21285	COG0203	ribosomal protein L17
EB230_RS21290	COG0202	RNA polymerase activity
EB230_RS21295	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EB230_RS21300	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EB230_RS21305	COG0563	adenylate kinase activity
EB230_RS21315	COG0200	Binds to the 23S rRNA
EB230_RS21320	COG1841	ribosomal large subunit assembly
EB230_RS21325	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EB230_RS21330	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EB230_RS21335	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EB230_RS21340	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EB230_RS21345	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EB230_RS21350	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EB230_RS21355	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EB230_RS21360	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EB230_RS21365	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EB230_RS21370	COG0255	Belongs to the universal ribosomal protein uL29 family
EB230_RS21375	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EB230_RS21380	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EB230_RS21385	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EB230_RS21390	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EB230_RS21395	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EB230_RS21400	COG0089	rRNA binding
EB230_RS21405	COG0088	Forms part of the polypeptide exit tunnel
EB230_RS21410	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EB230_RS21415	COG0051	transcription antitermination factor activity, RNA binding
EB230_RS21420	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EB230_RS21425	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EB230_RS21430	COG0049	tRNA binding
EB230_RS21435	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EB230_RS21460	COG3655	Transcriptional regulator
EB230_RS21465	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EB230_RS21470	COG0085	RNA polymerase activity
EB230_RS21475	COG0222	ribosome binding
EB230_RS21480	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EB230_RS21485	COG0081	regulation of translation
EB230_RS21490	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EB230_RS21500	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EB230_RS21540	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EB230_RS21555	COG2261	transglycosylase associated protein
EB230_RS21575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EB230_RS21580	COG2084	Dehydrogenase
EB230_RS21585	COG3622	Belongs to the hyi family
EB230_RS21590	COG3960	tartronate-semialdehyde synthase activity
EB230_RS21595	COG1414	Transcriptional regulator
EB230_RS21635	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EB230_RS21645	COG4208	sulfate ABC transporter
EB230_RS21650	COG3842	ATPase activity
EB230_RS21655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EB230_RS21665	COG0154	amidase activity
EB230_RS21670	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EB230_RS21700	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EB230_RS21705	COG0513	Belongs to the DEAD box helicase family
EB230_RS21715	COG2885	chlorophyll binding
EB230_RS21745	COG0860	N-Acetylmuramoyl-L-alanine amidase
EB230_RS21750	COG1530	ribonuclease E activity
EB230_RS21755	COG2066	Belongs to the glutaminase family
EB230_RS21760	COG0436	Aminotransferase
EB230_RS21775	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EB230_RS21780	COG0511	ligase activity, forming carbon-carbon bonds
EB230_RS21790	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EB230_RS21810	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EB230_RS21815	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EB230_RS21835	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EB230_RS21840	COG3811	Belongs to the UPF0386 family
EB230_RS21845	COG0516	GMP reductase activity
EB230_RS21845	COG0517	IMP dehydrogenase activity
EB230_RS21920	COG1278	Cold shock
EB230_RS21925	COG0346	lactoylglutathione lyase activity
EB230_RS21940	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EB230_RS21960	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EB230_RS21980	COG0494	nUDIX hydrolase
EB230_RS21985	COG1902	pentaerythritol trinitrate reductase activity
EB230_RS21995	COG1177	transmembrane transport
EB230_RS22000	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB230_RS22005	COG3842	ATPase activity
EB230_RS22020	COG4566	intracellular signal transduction
EB230_RS22045	COG2267	carboxylic ester hydrolase activity
EB230_RS22050	COG1058	Belongs to the CinA family
EB230_RS22050	COG1546	Belongs to the CinA family
EB230_RS22060	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EB230_RS22075	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EB230_RS22110	COG0586	Pfam SNARE associated Golgi protein
EB230_RS22125	COG1968	undecaprenyl-diphosphatase activity
EB230_RS22170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB230_RS22195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EB230_RS22220	COG0667	Aldo Keto reductase
EB230_RS22250	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EB230_RS22255	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EB230_RS22255	COG3608	succinylglutamate desuccinylase aspartoacylase
EB230_RS22270	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EB230_RS22275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EB230_RS22285	COG3191	aminopeptidase activity
EB230_RS22305	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EB230_RS22310	COG2514	catechol 2,3-dioxygenase activity
EB230_RS22330	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EB230_RS22335	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EB230_RS22340	COG0047	phosphoribosylformylglycinamidine synthase activity
EB230_RS22365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB230_RS22375	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EB230_RS22405	COG0037	tRNA processing
EB230_RS22410	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EB230_RS22430	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EB230_RS22435	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EB230_RS22440	COG0538	isocitrate dehydrogenase activity
EB230_RS22460	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EB230_RS22465	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EB230_RS22470	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EB230_RS22470	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EB230_RS22475	COG2313	pseudouridylate synthase activity
EB230_RS22485	COG3791	Glutathione-dependent formaldehyde-activating
EB230_RS22490	COG0316	Belongs to the HesB IscA family
EB230_RS22495	COG2151	metal-sulfur cluster biosynthetic enzyme
EB230_RS22500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EB230_RS22505	COG0719	Fe-S assembly protein
EB230_RS22510	COG0396	ATPase activity
EB230_RS22515	COG0719	Fe-S assembly protein
EB230_RS22525	COG2945	thiolester hydrolase activity
EB230_RS22535	COG0671	phosphoesterase, PA-phosphatase related
EB230_RS22540	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EB230_RS22550	COG0463	Glycosyl transferase, family 2
EB230_RS22555	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EB230_RS22565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EB230_RS22580	COG0739	heme binding
EB230_RS22585	COG1473	amidohydrolase
EB230_RS22590	COG0006	proline dipeptidase activity
EB230_RS22610	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS22645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB230_RS22655	COG3842	ATPase activity
EB230_RS22665	COG1175	transmembrane transport
EB230_RS22670	COG0395	ABC-type sugar transport system, permease component
EB230_RS22690	COG0776	regulation of translation
EB230_RS22700	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EB230_RS22705	COG0740	serine-type endopeptidase activity
EB230_RS22715	COG0076	glutamate decarboxylase activity
EB230_RS22720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB230_RS22725	COG2124	cytochrome p450
EB230_RS22740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EB230_RS22770	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EB230_RS22775	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EB230_RS22795	COG0010	Belongs to the arginase family
EB230_RS22800	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EB230_RS22810	COG1612	heme a metabolic process
EB230_RS22845	COG0297	glycogen (starch) synthase activity
EB230_RS22865	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EB230_RS22870	COG1396	sequence-specific DNA binding
EB230_RS22890	COG0776	regulation of translation
EB230_RS22895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EB230_RS22900	COG0416	fatty acid biosynthetic process
EB230_RS22915	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EB230_RS22925	COG0463	Glycosyl transferase, family 2
EB230_RS22930	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EB230_RS22935	COG1174	glycine betaine transport
EB230_RS22940	COG1125	glycine betaine transport
EB230_RS22945	COG1174	glycine betaine transport
EB230_RS22950	COG1732	Glycine betaine
EB230_RS22955	COG2814	Major facilitator Superfamily
EB230_RS22960	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EB230_RS22965	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EB230_RS22975	COG4453	Protein conserved in bacteria
EB230_RS22985	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EB230_RS22985	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EB230_RS22990	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EB230_RS23000	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EB230_RS23005	COG0025	NhaP-type Na H and K H
EB230_RS23010	COG2989	Protein conserved in bacteria
EB230_RS23025	COG1024	Enoyl-CoA hydratase
EB230_RS23035	COG0113	porphobilinogen synthase activity
EB230_RS23050	COG0667	Aldo Keto reductase
EB230_RS23125	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EB230_RS23135	COG0628	permease
EB230_RS23140	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EB230_RS23150	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EB230_RS23160	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EB230_RS23185	COG0477	Major facilitator Superfamily
EB230_RS23190	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EB230_RS23195	COG0248	Ppx GppA phosphatase
EB230_RS23195	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EB230_RS23340	COG3220	belongs to the UPF0276 family
EB230_RS23390	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EB230_RS23395	COG1132	(ABC) transporter
EB230_RS23400	COG3459	Glycosyltransferase 36 associated
EB230_RS23410	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EB230_RS23420	COG2986	histidine ammonia-lyase
EB230_RS23425	COG1228	amidohydrolase
EB230_RS23430	COG0402	S-adenosylhomocysteine deaminase activity
EB230_RS23440	COG0251	oxidation-reduction process
EB230_RS23450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EB230_RS23455	COG0803	Belongs to the bacterial solute-binding protein 9 family
EB230_RS23500	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EB230_RS23515	COG4589	Belongs to the CDS family
EB230_RS23525	COG1063	alcohol dehydrogenase
EB230_RS23530	COG0156	8-amino-7-oxononanoate synthase activity
EB230_RS23540	COG0726	polysaccharide deacetylase
EB230_RS23570	COG1902	pentaerythritol trinitrate reductase activity
EB230_RS23570	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB230_RS23575	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EB230_RS23590	COG0747	negative chemotaxis
EB230_RS23595	COG5598	trimethylamine methyltransferase
EB230_RS23600	COG0583	DNA-binding transcription factor activity
EB230_RS23615	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EB230_RS23645	COG1663	tetraacyldisaccharide 4'-kinase activity
EB230_RS23650	COG1519	Transferase
EB230_RS23665	COG0483	inositol monophosphate 1-phosphatase activity
EB230_RS23670	COG0312	modulator of DNA gyrase
EB230_RS23675	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EB230_RS23680	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EB230_RS23690	COG0612	Peptidase, M16
EB230_RS23695	COG0612	Peptidase, M16
EB230_RS23700	COG0742	ribosomal rna small subunit methyltransferase
EB230_RS23710	COG0590	tRNA wobble adenosine to inosine editing
EB230_RS23720	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EB230_RS23735	COG0196	riboflavin kinase activity
EB230_RS23750	COG1280	lysine exporter protein (LysE YggA)
EB230_RS23770	COG1914	H( )-stimulated, divalent metal cation uptake system
EB230_RS23785	COG2814	Major facilitator Superfamily
EB230_RS23790	COG1566	PFAM secretion protein HlyD family protein
EB230_RS23800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EB230_RS23810	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EB230_RS23820	COG3708	Transcriptional regulator
EB230_RS23820	COG2207	Transcriptional regulator
EB230_RS23825	COG0456	acetyltransferase
EB230_RS23825	COG1846	Transcriptional regulator
EB230_RS23850	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EB230_RS23855	COG0459	protein refolding
EB230_RS23880	COG1280	lysine exporter protein (LysE YggA)
EB230_RS23905	COG1278	Cold shock
EB230_RS23925	COG3237	CsbD-like
EB230_RS23955	COG1309	transcriptional regulator
EB230_RS23970	COG0114	fumarate hydratase activity
EB230_RS23975	COG2259	Doxx family
EB230_RS23990	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EB230_RS24000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EB230_RS24010	COG1126	abc transporter atp-binding protein
EB230_RS24015	COG0765	amino acid transport
EB230_RS24020	COG4597	amino acid ABC transporter
EB230_RS24025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB230_RS24030	COG0626	cystathionine gamma-synthase activity
EB230_RS24050	COG3794	PFAM blue (type 1) copper domain protein
EB230_RS24055	COG1024	Enoyl-CoA hydratase
EB230_RS24070	COG0438	transferase activity, transferring glycosyl groups
EB230_RS24075	COG3706	GGDEF domain
EB230_RS24110	COG0628	permease
EB230_RS24120	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EB230_RS24125	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EB230_RS24165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB230_RS24180	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EB230_RS24200	COG1473	amidohydrolase
EB230_RS24210	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EB230_RS24215	COG1522	sequence-specific DNA binding
EB230_RS24220	COG2072	flavoprotein involved in K transport
EB230_RS24225	COG0243	molybdopterin cofactor binding
EB230_RS24230	COG0488	(ABC) transporter
EB230_RS24235	COG4957	zinc ion binding
EB230_RS24275	COG0105	UTP biosynthetic process
EB230_RS24280	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EB230_RS24285	COG0314	molybdopterin synthase activity
EB230_RS24295	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EB230_RS24300	COG0322	excinuclease ABC activity
EB230_RS24315	COG0625	glutathione transferase activity
EB230_RS24340	COG1309	transcriptional regulator
EB230_RS24360	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EB230_RS24385	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EB230_RS24410	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EB230_RS24415	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EB230_RS24420	COG1982	Orn Lys Arg decarboxylase major
EB230_RS24425	COG0531	amino acid
EB230_RS24435	COG0531	amino acid
EB230_RS24440	COG0194	GDP metabolic process
EB230_RS24445	COG1561	YicC-like family, N-terminal region
EB230_RS24450	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EB230_RS24455	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EB230_RS24460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EB230_RS24470	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EB230_RS24475	COG1368	sulfuric ester hydrolase activity
EB230_RS24485	COG0360	Binds together with S18 to 16S ribosomal RNA
EB230_RS24490	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EB230_RS24495	COG0359	binds to the 23S rRNA
EB230_RS24500	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EB230_RS24505	COG1742	UPF0060 membrane protein
EB230_RS24530	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EB230_RS24535	COG4221	oxidoreductase activity
EB230_RS24555	COG0697	spore germination
EB230_RS24565	COG0583	DNA-binding transcription factor activity
EB230_RS24585	COG1309	transcriptional regulator
EB230_RS24590	COG1183	phosphatidylcholine synthase activity
EB230_RS24595	COG0688	phosphatidylethanolamine metabolic process
EB230_RS24600	COG3386	PFAM SMP-30 Gluconolaconase
EB230_RS24610	COG5265	(ABC) transporter
EB230_RS24615	COG0640	Transcriptional regulator
EB230_RS24620	COG0583	DNA-binding transcription factor activity
EB230_RS24625	COG2249	NAD(P)H dehydrogenase (quinone) activity
EB230_RS24630	COG1652	LysM domain
EB230_RS24650	COG1216	Glycosyl transferase, family 2
EB230_RS24660	COG0598	Magnesium transport protein CorA
EB230_RS24670	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EB230_RS24695	COG0215	cysteine-tRNA ligase activity
EB230_RS24735	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EB230_RS24740	COG0354	folic acid binding
EB230_RS24745	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EB230_RS24750	COG5001	Diguanylate cyclase
EB230_RS24760	COG0583	DNA-binding transcription factor activity
EB230_RS24785	COG1595	DNA-templated transcription, initiation
EB230_RS24800	COG1381	Involved in DNA repair and RecF pathway recombination
EB230_RS24810	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EB230_RS24815	COG0571	ribonuclease III activity
EB230_RS24820	COG0681	Belongs to the peptidase S26 family
EB230_RS24825	COG0736	holo-[acyl-carrier-protein] synthase activity
EB230_RS24840	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EB230_RS24850	COG1758	RNA polymerase activity
EB230_RS24870	COG1733	regulation of RNA biosynthetic process
EB230_RS24880	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EB230_RS24885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EB230_RS24890	COG0741	lytic transglycosylase activity
EB230_RS24905	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EB230_RS24915	COG2827	Endonuclease containing a URI domain
EB230_RS24925	COG0457	Tetratricopeptide repeat
EB230_RS24930	COG0457	Tetratricopeptide repeat
EB230_RS24935	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EB230_RS24940	COG1846	Transcriptional regulator
EB230_RS24940	COG0456	acetyltransferase
EB230_RS24945	COG1254	Belongs to the acylphosphatase family
EB230_RS24955	COG1960	acyl-CoA dehydrogenase activity
EB230_RS24960	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EB230_RS24965	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EB230_RS24975	COG4770	biotin carboxylase activity
EB230_RS25005	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EB230_RS25050	COG0308	aminopeptidase N
EB230_RS25055	COG2205	protein histidine kinase activity
EB230_RS25055	COG2202	Pas domain
EB230_RS25065	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EB230_RS25075	COG0745	RESPONSE REGULATOR receiver
EB230_RS25080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EB230_RS25085	COG3088	subunit of a heme lyase
EB230_RS25090	COG1138	Cytochrome C-type biogenesis protein
EB230_RS25095	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EB230_RS25100	COG4235	cytochrome complex assembly
EB230_RS25115	COG0745	RESPONSE REGULATOR receiver
EB230_RS25150	COG3842	ATPase activity
EB230_RS25170	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EB230_RS25200	COG3409	Peptidoglycan-binding domain 1 protein
EB230_RS25200	COG3429	Glucose-6-phosphate dehydrogenase subunit
EB230_RS25205	COG2205	protein histidine kinase activity
EB230_RS25215	COG2166	iron-sulfur cluster assembly
EB230_RS25235	COG1280	lysine exporter protein (LysE YggA)
EB230_RS25245	COG2010	Cytochrome c
EB230_RS25255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EB230_RS25260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EB230_RS25270	COG1376	ErfK ybiS ycfS ynhG family protein
EB230_RS25275	COG0433	COG0433 Predicted ATPase
EB230_RS25295	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EB230_RS25310	COG0183	Belongs to the thiolase family
EB230_RS25315	COG1309	transcriptional regulator
EB230_RS25320	COG3119	arylsulfatase activity
EB230_RS25330	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EB230_RS25335	COG1012	belongs to the aldehyde dehydrogenase family
EB230_RS25380	COG4172	Belongs to the ABC transporter superfamily
EB230_RS25385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB230_RS25390	COG0601	transmembrane transport
EB230_RS25395	COG4166	transmembrane transport
EB230_RS25410	COG0366	Alpha amylase catalytic
EB230_RS25415	COG1523	belongs to the glycosyl hydrolase 13 family
EB230_RS25420	COG0033	Phosphoglucomutase
EB230_RS25425	COG0297	glycogen (starch) synthase activity
EB230_RS25430	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EB230_RS25435	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EB230_RS25440	COG0058	SHG alpha-glucan phosphorylase activity
EB230_RS25485	COG1218	3'(2'),5'-bisphosphate nucleotidase
EB230_RS25495	COG0175	sulfate reduction
EB230_RS25500	COG3307	-O-antigen
EB230_RS25510	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EB230_RS25520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EB230_RS25550	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EB230_RS25555	COG0438	transferase activity, transferring glycosyl groups
EB230_RS25560	COG2226	methyltransferase
EB230_RS25570	COG2813	Specifically methylates the guanine in position
EB230_RS25595	COG2076	Multidrug Resistance protein
EB230_RS25600	COG2226	methyltransferase
EB230_RS25620	COG1091	dTDP-4-dehydrorhamnose reductase activity
EB230_RS25625	COG1088	dTDP-glucose 4,6-dehydratase activity
EB230_RS25630	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
EB230_RS25645	COG1268	BioY protein
EB230_RS25685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EB230_RS25685	COG0574	Belongs to the PEP-utilizing enzyme family
EB230_RS25705	COG0583	DNA-binding transcription factor activity
EB230_RS25710	COG0747	negative chemotaxis
EB230_RS25720	COG1196	nuclear chromosome segregation
EB230_RS25725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EB230_RS25735	COG1194	a g-specific adenine glycosylase
EB230_RS25745	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EB230_RS25750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EB230_RS25765	COG0612	Peptidase, M16
EB230_RS25770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EB230_RS25780	COG1678	Uncharacterized ACR, COG1678
EB230_RS25790	COG0678	peroxiredoxin activity
EB230_RS25805	COG0328	RNA-DNA hybrid ribonuclease activity
EB230_RS25810	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EB230_RS25815	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EB230_RS25820	COG3346	SURF1 family
EB230_RS25840	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EB230_RS25850	COG0109	protoheme IX farnesyltransferase activity
EB230_RS25855	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EB230_RS25860	COG1565	acr, cog1565
EB230_RS25860	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EB230_RS25870	COG0312	modulator of DNA gyrase
EB230_RS25895	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EB230_RS25915	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EB230_RS25920	COG1741	Belongs to the pirin family
EB230_RS25930	COG1722	exodeoxyribonuclease VII activity
EB230_RS25935	COG0123	including yeast histone deacetylase and acetoin utilization protein
EB230_RS25940	COG0778	Nitroreductase
EB230_RS25950	COG1309	transcriptional regulator
EB230_RS25960	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EB230_RS25960	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EB230_RS25965	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EB230_RS25975	COG0406	alpha-ribazole phosphatase activity
EB230_RS25980	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EB230_RS25985	COG0484	heat shock protein binding
EB230_RS25995	COG0259	pyridoxamine-phosphate oxidase activity
EB230_RS26000	COG1024	Enoyl-CoA hydratase
EB230_RS26005	COG1960	acyl-CoA dehydrogenase activity
EB230_RS26030	COG0151	Belongs to the GarS family
EB230_RS26040	COG0583	DNA-binding transcription factor activity
EB230_RS26045	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EB230_RS26055	COG0277	FAD linked oxidase domain protein
EB230_RS26060	COG0009	L-threonylcarbamoyladenylate synthase
EB230_RS26080	COG0751	glycine-tRNA ligase activity
EB230_RS26095	COG0752	glycyl-tRNA synthetase alpha subunit
EB230_RS26120	COG0142	geranyltranstransferase activity
EB230_RS26145	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EB230_RS26150	COG0521	Mo-molybdopterin cofactor biosynthetic process
EB230_RS26175	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EB230_RS26180	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EB230_RS26185	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EB230_RS26190	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EB230_RS26195	COG0356	it plays a direct role in the translocation of protons across the membrane
EB230_RS26220	COG0583	DNA-binding transcription factor activity
EB230_RS26225	COG1160	GTP binding
EB230_RS26230	COG2976	Protein conserved in bacteria
EB230_RS26240	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EB230_RS26245	COG0477	Major facilitator Superfamily
EB230_RS26255	COG0583	DNA-binding transcription factor activity
EB230_RS26260	COG2309	aminopeptidase activity
EB230_RS26270	COG1393	Belongs to the ArsC family
EB230_RS26275	COG0640	Transcriptional regulator
EB230_RS26295	COG3842	ATPase activity
EB230_RS26310	COG1177	transmembrane transport
EB230_RS26315	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB230_RS26325	COG1129	ABC transporter
EB230_RS26335	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS26350	COG1309	transcriptional regulator
EB230_RS26360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB230_RS26365	COG0583	DNA-binding transcription factor activity
EB230_RS26380	COG4948	Mandelate Racemase Muconate Lactonizing
EB230_RS26385	COG4948	Mandelate Racemase Muconate Lactonizing
EB230_RS26390	COG0747	negative chemotaxis
EB230_RS26400	COG0601	transmembrane transport
EB230_RS26420	COG0747	negative chemotaxis
EB230_RS26430	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS26440	COG2113	Glycine betaine
EB230_RS26445	COG4175	Glycine betaine
EB230_RS26450	COG4176	ABC-type proline glycine betaine transport system permease component
EB230_RS26485	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB230_RS26505	COG0531	amino acid
EB230_RS26520	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EB230_RS26525	COG2218	PFAM glutamate synthase alpha subunit domain protein
EB230_RS26530	COG0069	glutamate synthase activity
EB230_RS26540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB230_RS26545	COG4311	Sarcosine oxidase, delta subunit
EB230_RS26550	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB230_RS26550	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB230_RS26560	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB230_RS26590	COG0318	PFAM AMP-dependent synthetase and ligase
EB230_RS26600	COG3347	Dehydrogenase
EB230_RS26600	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS26615	COG1129	ABC transporter
EB230_RS26620	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EB230_RS26625	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EB230_RS26640	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EB230_RS26645	COG2376	Dihydroxyacetone kinase
EB230_RS26650	COG1461	Dihydroxyacetone kinase
EB230_RS26670	COG0149	triose-phosphate isomerase activity
EB230_RS26700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EB230_RS26710	COG3842	ATPase activity
EB230_RS26725	COG1175	transmembrane transport
EB230_RS26730	COG1653	transport
EB230_RS26740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EB230_RS26755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EB230_RS26765	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS26770	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS26795	COG0174	glutamine synthetase
EB230_RS26805	COG1737	Transcriptional regulator
EB230_RS26810	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EB230_RS26815	COG2971	BadF BadG BcrA BcrD
EB230_RS26820	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EB230_RS26825	COG0747	negative chemotaxis
EB230_RS26830	COG0601	transmembrane transport
EB230_RS26840	COG4172	Belongs to the ABC transporter superfamily
EB230_RS26845	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EB230_RS26850	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EB230_RS26860	COG2204	response regulator
EB230_RS26865	COG4191	Histidine kinase
EB230_RS26870	COG1301	dicarboxylic acid transport
EB230_RS26880	COG1940	carbohydrate kinase activity
EB230_RS26900	COG0673	inositol 2-dehydrogenase activity
EB230_RS26910	COG0395	ABC-type sugar transport system, permease component
EB230_RS26920	COG1653	transport
EB230_RS26940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB230_RS26945	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
EB230_RS26965	COG2268	Band 7 protein
EB230_RS26965	COG2268	Band 7 protein
EB230_RS26970	COG5441	Belongs to the UPF0261 family
EB230_RS26990	COG0559	Belongs to the binding-protein-dependent transport system permease family
EB230_RS27000	COG0596	Alpha beta hydrolase
EB230_RS27005	COG0179	Fumarylacetoacetate (FAA) hydrolase
EB230_RS27010	COG2186	Transcriptional regulator
EB230_RS27025	COG3485	protocatechuate 3,4-dioxygenase
EB230_RS27030	COG3485	protocatechuate 3,4-dioxygenase
EB230_RS27035	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EB230_RS27040	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EB230_RS27045	COG0583	DNA-binding transcription factor activity
EB230_RS27085	COG3842	ATPase activity
EB230_RS27090	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB230_RS27095	COG1177	transmembrane transport
EB230_RS27100	COG0277	FAD linked oxidase domain protein
EB230_RS27115	COG0667	Aldo Keto reductase
EB230_RS27145	COG0559	Belongs to the binding-protein-dependent transport system permease family
EB230_RS27155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB230_RS27160	COG1802	Transcriptional regulator
EB230_RS27165	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EB230_RS27175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB230_RS27240	COG0823	Involved in the tonB-independent uptake of proteins
EB230_RS27240	COG4946	Tricorn protease homolog
EB230_RS27240	COG1506	peptidase
EB230_RS27255	COG0601	transmembrane transport
EB230_RS27265	COG0444	Belongs to the ABC transporter superfamily
EB230_RS27270	COG4608	Belongs to the ABC transporter superfamily
EB230_RS27280	COG0583	DNA-binding transcription factor activity
EB230_RS27315	COG3618	amidohydrolase
EB230_RS27330	COG1175	transmembrane transport
EB230_RS27335	COG0395	ABC-type sugar transport system, permease component
EB230_RS27340	COG3842	ATPase activity
EB230_RS27345	COG4948	Mandelate Racemase Muconate Lactonizing
EB230_RS27350	COG3254	rhamnose metabolic process
EB230_RS27385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EB230_RS27395	COG1012	belongs to the aldehyde dehydrogenase family
EB230_RS27405	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EB230_RS27415	COG0583	DNA-binding transcription factor activity
EB230_RS27425	COG1349	DNA-binding transcription factor activity
EB230_RS27435	COG3608	succinylglutamate desuccinylase aspartoacylase
EB230_RS27440	COG0006	proline dipeptidase activity
EB230_RS27445	COG2423	ornithine cyclodeaminase activity
EB230_RS27450	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EB230_RS27460	COG0765	amino acid transport
EB230_RS27465	COG0765	amino acid transport
EB230_RS27470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB230_RS27475	COG1126	abc transporter atp-binding protein
EB230_RS27480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB230_RS27485	COG1522	sequence-specific DNA binding
EB230_RS27490	COG1012	belongs to the aldehyde dehydrogenase family
EB230_RS27495	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EB230_RS27500	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS27500	COG3321	synthase
EB230_RS27500	COG0604	alcohol dehydrogenase
EB230_RS27505	COG2986	histidine ammonia-lyase
EB230_RS27510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EB230_RS27515	COG1132	(ABC) transporter
EB230_RS27520	COG1132	(ABC) transporter
EB230_RS27525	COG0477	Major facilitator Superfamily
EB230_RS27565	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EB230_RS27570	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS27575	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EB230_RS27580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB230_RS27585	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EB230_RS27595	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EB230_RS27615	COG0747	negative chemotaxis
EB230_RS27620	COG0583	DNA-binding transcription factor activity
EB230_RS27630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EB230_RS27640	COG5598	trimethylamine methyltransferase
EB230_RS27645	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EB230_RS27680	COG0251	oxidation-reduction process
EB230_RS27720	COG0386	Belongs to the glutathione peroxidase family
EB230_RS27725	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS27745	COG1404	Belongs to the peptidase S8 family
EB230_RS27750	COG1864	DNA RNA non-specific endonuclease
EB230_RS27750	COG3591	Belongs to the peptidase S1B family
EB230_RS27845	COG2885	chlorophyll binding
EB230_RS27895	COG3501	Rhs element vgr protein
EB230_RS27905	COG3047	cAMP biosynthetic process
EB230_RS27905	COG2885	chlorophyll binding
EB230_RS27930	COG0739	heme binding
EB230_RS27980	COG0459	protein refolding
EB230_RS28005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EB230_RS28010	COG3350	monooxygenase activity
EB230_RS28070	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EB230_RS28070	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EB230_RS28100	COG0653	protein targeting
EB230_RS28120	COG1879	ABC-type sugar transport system periplasmic component
EB230_RS28125	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS28130	COG1129	ABC transporter
EB230_RS28140	COG1454	alcohol dehydrogenase
EB230_RS28155	COG1012	belongs to the aldehyde dehydrogenase family
EB230_RS28160	COG0583	DNA-binding transcription factor activity
EB230_RS28175	COG2268	Band 7 protein
EB230_RS28190	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS28205	COG1129	ABC transporter
EB230_RS28210	COG1879	ABC-type sugar transport system periplasmic component
EB230_RS28215	COG0642	Histidine kinase
EB230_RS28220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB230_RS28235	COG1012	belongs to the aldehyde dehydrogenase family
EB230_RS28240	COG1126	abc transporter atp-binding protein
EB230_RS28245	COG0765	amino acid transport
EB230_RS28255	COG3938	Belongs to the proline racemase family
EB230_RS28260	COG1802	Transcriptional regulator
EB230_RS28275	COG3386	PFAM SMP-30 Gluconolaconase
EB230_RS28280	COG1012	belongs to the aldehyde dehydrogenase family
EB230_RS28285	COG1012	belongs to the aldehyde dehydrogenase family
EB230_RS28290	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EB230_RS28305	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS28310	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS28315	COG1129	ABC transporter
EB230_RS28320	COG1879	ABC-type sugar transport system periplasmic component
EB230_RS28330	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EB230_RS28335	COG2181	nitrate reductase activity
EB230_RS28335	COG0247	lactate metabolic process
EB230_RS28365	COG1473	amidohydrolase
EB230_RS28385	COG1902	pentaerythritol trinitrate reductase activity
EB230_RS28390	COG1012	belongs to the aldehyde dehydrogenase family
EB230_RS28395	COG2207	Transcriptional regulator
EB230_RS28395	COG0662	Cupin 2, conserved barrel domain protein
EB230_RS28400	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EB230_RS28405	COG2084	Dehydrogenase
EB230_RS28410	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB230_RS28410	COG0596	Alpha beta hydrolase
EB230_RS28425	COG0519	Catalyzes the synthesis of GMP from XMP
EB230_RS28425	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EB230_RS28440	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EB230_RS28445	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EB230_RS28445	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EB230_RS28450	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EB230_RS28455	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EB230_RS28470	COG0765	amino acid transport
EB230_RS28510	COG0318	PFAM AMP-dependent synthetase and ligase
EB230_RS28515	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EB230_RS28520	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EB230_RS28525	COG0124	histidyl-tRNA synthetase
EB230_RS28535	COG2818	Glycosylase
EB230_RS28540	COG1376	ErfK ybiS ycfS ynhG family protein
EB230_RS28545	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EB230_RS28550	COG0247	lactate metabolic process
EB230_RS28555	COG0277	FAD linked oxidase domain protein
EB230_RS28560	COG0277	FAD linked oxidase domain protein
EB230_RS28570	COG2186	Transcriptional regulator
EB230_RS28615	COG0583	DNA-binding transcription factor activity
EB230_RS28620	COG1570	exodeoxyribonuclease VII activity
EB230_RS28650	COG2808	Putative FMN-binding domain
EB230_RS28675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB230_RS28680	COG1737	Transcriptional regulator
EB230_RS28680	COG0837	glucose binding
EB230_RS28690	COG0174	glutamine synthetase
EB230_RS28705	COG0277	FAD linked oxidase domain protein
EB230_RS28710	COG1312	Catalyzes the dehydration of D-mannonate
EB230_RS28715	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS28735	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS28740	COG3769	mannosylglycerate metabolic process
EB230_RS28770	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EB230_RS28785	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EB230_RS28790	COG1845	cytochrome c oxidase, subunit III
EB230_RS28795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EB230_RS28800	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EB230_RS28805	COG0477	Major facilitator Superfamily
EB230_RS28825	COG1376	ErfK ybiS ycfS ynhG family protein
EB230_RS28835	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EB230_RS28845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB230_RS28850	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
EB230_RS28860	COG1596	polysaccharide export
EB230_RS28870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EB230_RS28875	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EB230_RS28880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EB230_RS28885	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EB230_RS28910	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EB230_RS28925	COG0367	asparagine synthase
EB230_RS28960	COG1012	belongs to the aldehyde dehydrogenase family
EB230_RS28985	COG1177	transmembrane transport
EB230_RS28990	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB230_RS29000	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EB230_RS29015	COG4214	carbohydrate transport
EB230_RS29035	COG3842	ATPase activity
EB230_RS29040	COG2235	arginine
EB230_RS29045	COG1177	transmembrane transport
EB230_RS29050	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB230_RS29060	COG1609	Transcriptional regulator
EB230_RS29085	COG1653	transport
EB230_RS29100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB230_RS29110	COG0434	BtpA family
EB230_RS29135	COG0673	inositol 2-dehydrogenase activity
EB230_RS29145	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS29150	COG1129	ABC transporter
EB230_RS29155	COG0673	inositol 2-dehydrogenase activity
EB230_RS29165	COG1312	Catalyzes the dehydration of D-mannonate
EB230_RS29195	COG1215	transferase activity, transferring glycosyl groups
EB230_RS29205	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EB230_RS29235	COG5598	trimethylamine methyltransferase
EB230_RS29245	COG4175	Glycine betaine
EB230_RS29245	COG3448	diguanylate cyclase activity
EB230_RS29250	COG4176	ABC-type proline glycine betaine transport system permease component
EB230_RS29270	COG1129	ABC transporter
EB230_RS29280	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS29290	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS29295	COG1024	Enoyl-CoA hydratase
EB230_RS29300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EB230_RS29310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB230_RS29320	COG4638	Rieske (2fe-2S)
EB230_RS29325	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS29355	COG1802	Transcriptional regulator
EB230_RS29385	COG0579	oxidoreductase
EB230_RS29400	COG3246	L-lysine catabolic process to acetate
EB230_RS29420	COG1012	belongs to the aldehyde dehydrogenase family
EB230_RS29430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB230_RS29440	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB230_RS29450	COG3842	ATPase activity
EB230_RS29470	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS29475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB230_RS29480	COG1126	abc transporter atp-binding protein
EB230_RS29485	COG0765	amino acid transport
EB230_RS29490	COG0765	amino acid transport
EB230_RS29500	COG4221	oxidoreductase activity
EB230_RS29510	COG0022	dehydrogenase e1 component
EB230_RS29510	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB230_RS29515	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EB230_RS29525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB230_RS29530	COG4221	oxidoreductase activity
EB230_RS29550	COG1902	pentaerythritol trinitrate reductase activity
EB230_RS29550	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB230_RS29560	COG0697	spore germination
EB230_RS29580	COG5490	Phasin protein
EB230_RS29585	COG2205	protein histidine kinase activity
EB230_RS29590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EB230_RS29600	COG1177	transmembrane transport
EB230_RS29605	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB230_RS29610	COG3842	ATPase activity
EB230_RS29630	COG2224	Isocitrate lyase
EB230_RS29650	COG0174	glutamine synthetase
EB230_RS29660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB230_RS29675	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EB230_RS29680	COG0363	glucosamine-6-phosphate deaminase activity
EB230_RS29685	COG0129	dihydroxy-acid dehydratase activity
EB230_RS29690	COG2304	oxidoreductase activity
EB230_RS29700	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EB230_RS29720	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EB230_RS29750	COG3775	system Galactitol-specific IIC component
EB230_RS29795	COG4177	L-phenylalanine transmembrane transporter activity
EB230_RS29800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB230_RS29860	COG4964	Belongs to the GSP D family
EB230_RS29910	COG2274	protein secretion by the type I secretion system
EB230_RS29950	COG3706	GGDEF domain
EB230_RS29975	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EB230_RS29985	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EB230_RS29990	COG5328	Belongs to the UPF0262 family
EB230_RS30000	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EB230_RS30005	COG0424	maF-like protein
EB230_RS30010	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EB230_RS30015	COG1486	melibiose metabolic process
EB230_RS30025	COG0582	viral genome integration into host DNA
EB230_RS30055	COG3177	Filamentation induced by cAMP protein fic
EB230_RS30085	COG2010	Cytochrome c
EB230_RS30115	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EB230_RS30125	COG2948	multi-organism process
EB230_RS30150	COG3451	type IV secretory pathway VirB4
EB230_RS30160	COG3838	Conjugal transfer protein Trbc
EB230_RS30165	COG4962	Type ii secretion system protein e
EB230_RS30185	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EB230_RS30195	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EB230_RS30200	COG3916	Acyl-homoserine-lactone synthase
EB230_RS30220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EB230_RS30300	COG0745	RESPONSE REGULATOR receiver
EB230_RS30340	COG1304	FMN binding
EB230_RS30350	COG1657	PFAM Prenyltransferase squalene oxidase
EB230_RS30355	COG0142	geranyltranstransferase activity
EB230_RS30360	COG2124	cytochrome p450
EB230_RS30365	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS30370	COG2124	cytochrome p450
EB230_RS30375	COG2124	cytochrome p450
EB230_RS30495	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EB230_RS30515	COG4959	Type IV secretory pathway protease TraF
EB230_RS30545	COG0583	DNA-binding transcription factor activity
EB230_RS30550	COG3153	acetyltransferase
EB230_RS30555	COG3594	Acyltransferase
EB230_RS30570	COG0583	DNA-binding transcription factor activity
EB230_RS30590	COG0726	polysaccharide deacetylase
EB230_RS30615	COG2192	nodulation
EB230_RS30625	COG1131	(ABC) transporter
EB230_RS30630	COG1215	transferase activity, transferring glycosyl groups
EB230_RS30635	COG3153	acetyltransferase
EB230_RS30740	COG1525	nuclease
EB230_RS30760	COG3591	Belongs to the peptidase S1B family
EB230_RS30760	COG1864	DNA RNA non-specific endonuclease
EB230_RS30820	COG3047	cAMP biosynthetic process
EB230_RS30855	COG4957	zinc ion binding
EB230_RS30865	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EB230_RS30870	COG3328	transposase activity
EB230_RS30875	COG1476	TRANSCRIPTIONal
EB230_RS30910	COG2197	response regulator
EB230_RS30915	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EB230_RS30940	COG1522	sequence-specific DNA binding
EB230_RS30945	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EB230_RS30945	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EB230_RS30960	COG2301	Belongs to the HpcH HpaI aldolase family
EB230_RS30970	COG3799	methylaspartate ammonia-lyase activity
EB230_RS30975	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EB230_RS30980	COG1181	Belongs to the D-alanine--D-alanine ligase family
EB230_RS31015	COG2843	Capsule synthesis protein
EB230_RS31020	COG4608	Belongs to the ABC transporter superfamily
EB230_RS31025	COG0444	Belongs to the ABC transporter superfamily
EB230_RS31030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB230_RS31035	COG0601	transmembrane transport
EB230_RS31040	COG0747	negative chemotaxis
EB230_RS31060	COG3608	succinylglutamate desuccinylase aspartoacylase
EB230_RS31090	COG0006	proline dipeptidase activity
EB230_RS31095	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EB230_RS31100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB230_RS31105	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS31110	COG4172	Belongs to the ABC transporter superfamily
EB230_RS31120	COG0601	transmembrane transport
EB230_RS31130	COG0747	negative chemotaxis
EB230_RS31140	COG0596	Alpha beta hydrolase
EB230_RS31145	COG1522	sequence-specific DNA binding
EB230_RS31150	COG0583	DNA-binding transcription factor activity
EB230_RS31155	COG1181	Belongs to the D-alanine--D-alanine ligase family
EB230_RS31195	COG2771	luxR family
EB230_RS31215	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EB230_RS31225	COG0316	Belongs to the HesB IscA family
EB230_RS31235	COG0602	queuosine metabolic process
EB230_RS31240	COG0720	synthase
EB230_RS31250	COG1609	Transcriptional regulator
EB230_RS31270	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EB230_RS31280	COG3383	formate dehydrogenase (NAD+) activity
EB230_RS31295	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EB230_RS31295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EB230_RS31320	COG4689	acetoacetate decarboxylase
EB230_RS31340	COG0745	RESPONSE REGULATOR receiver
EB230_RS31350	COG1433	Dinitrogenase iron-molybdenum cofactor
EB230_RS31355	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EB230_RS31360	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EB230_RS31365	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EB230_RS31370	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EB230_RS31375	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
EB230_RS31405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB230_RS31415	COG4608	Belongs to the ABC transporter superfamily
EB230_RS31420	COG0444	Belongs to the ABC transporter superfamily
EB230_RS31430	COG1349	DNA-binding transcription factor activity
EB230_RS31435	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EB230_RS31445	COG0367	asparagine synthase
EB230_RS31460	COG1213	nucleotidyl transferase
EB230_RS31475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB230_RS31485	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS31490	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EB230_RS31500	COG2124	cytochrome p450
EB230_RS31515	COG0678	peroxiredoxin activity
EB230_RS31520	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EB230_RS31530	COG3383	formate dehydrogenase (NAD+) activity
EB230_RS31535	COG5420	small protein containing a coiled-coil domain
EB230_RS31540	COG5265	(ABC) transporter
EB230_RS31550	COG1104	cysteine desulfurase activity
EB230_RS31560	COG2086	electron transfer activity
EB230_RS31565	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EB230_RS31570	COG0644	oxidoreductase
EB230_RS31585	COG0535	radical SAM domain protein
EB230_RS31595	COG5554	nitrogen fixation
EB230_RS31600	COG5554	nitrogen fixation
EB230_RS31610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EB230_RS31615	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EB230_RS31650	COG2204	response regulator
EB230_RS31655	COG4191	Histidine kinase
EB230_RS31660	COG1301	dicarboxylic acid transport
EB230_RS31670	COG3604	Transcriptional regulator
EB230_RS31680	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EB230_RS31690	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EB230_RS31695	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EB230_RS31710	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EB230_RS31725	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EB230_RS31735	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EB230_RS31765	COG0459	protein refolding
EB230_RS31785	COG1012	belongs to the aldehyde dehydrogenase family
EB230_RS31820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EB230_RS31830	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EB230_RS31835	COG0720	synthase
EB230_RS31840	COG0602	queuosine metabolic process
EB230_RS31845	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EB230_RS31860	COG2022	thiamine diphosphate biosynthetic process
EB230_RS31870	COG0351	phosphomethylpyrimidine kinase
EB230_RS31875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB230_RS31880	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EB230_RS31920	COG0210	DNA helicase
EB230_RS31950	COG4952	isomerase
EB230_RS31955	COG3347	Dehydrogenase
EB230_RS31955	COG1028	Short-chain dehydrogenase reductase Sdr
EB230_RS31960	COG1349	DNA-binding transcription factor activity
EB230_RS31970	COG1129	ABC transporter
EB230_RS31975	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS31980	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB230_RS31985	COG3254	rhamnose metabolic process
EB230_RS31990	COG1070	Carbohydrate kinase
EB230_RS31995	COG3457	Alanine racemase
EB230_RS32000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB230_RS32010	COG0156	8-amino-7-oxononanoate synthase activity
EB230_RS32015	COG0436	Aminotransferase
EB230_RS32020	COG1970	mechanosensitive ion channel activity
EB230_RS32025	COG2205	protein histidine kinase activity
EB230_RS32025	COG0784	Response regulator, receiver
EB230_RS32050	COG0167	dihydroorotate dehydrogenase activity
EB230_RS32055	COG0534	Mate efflux family protein
EB230_RS32060	COG0123	including yeast histone deacetylase and acetoin utilization protein
EB230_RS32085	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EB230_RS32085	COG2755	lipolytic protein G-D-S-L family
EB230_RS32120	COG2197	response regulator
EB230_RS32135	COG1129	ABC transporter
EB230_RS32140	COG4214	carbohydrate transport
EB230_RS32155	COG1376	ErfK ybiS ycfS ynhG family protein
EB230_RS32160	COG0717	Belongs to the dCTP deaminase family
EB230_RS32175	COG2967	ApaG domain
EB230_RS32185	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EB230_RS32190	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EB230_RS32200	COG0598	Magnesium transport protein CorA
EB230_RS32205	COG0704	Plays a role in the regulation of phosphate uptake
EB230_RS32210	COG5002	protein histidine kinase activity
EB230_RS32215	COG2326	polyphosphate kinase activity
EB230_RS32220	COG1024	Enoyl-CoA hydratase
EB230_RS32230	COG2197	response regulator
EB230_RS32245	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EB230_RS32265	COG1250	3-hydroxyacyl-CoA dehydrogenase
EB230_RS32265	COG1024	Enoyl-CoA hydratase
EB230_RS32270	COG0183	Belongs to the thiolase family
EB230_RS32275	COG1960	acyl-CoA dehydrogenase activity
EB230_RS32280	COG1960	acyl-CoA dehydrogenase activity
EB230_RS32285	COG0789	Transcriptional regulator
EB230_RS32295	COG0730	response to heat
EB230_RS32305	COG0443	Heat shock 70 kDa protein
EB230_RS32315	COG0243	molybdopterin cofactor binding
EB230_RS32320	COG0437	4 iron, 4 sulfur cluster binding
EB230_RS32325	COG3302	dmso reductase anchor subunit
EB230_RS32335	COG1201	RNA secondary structure unwinding
EB230_RS32340	COG0791	NLP P60 protein
EB230_RS32350	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EB230_RS32385	COG4964	Belongs to the GSP D family
EB230_RS32425	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EB230_RS32430	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EB230_RS32435	COG1024	Enoyl-CoA hydratase
EB230_RS32440	COG0268	Binds directly to 16S ribosomal RNA