locus-tag	class	description
EB231_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EB231_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EB231_RS00025	COG0456	acetyltransferase
EB231_RS00030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EB231_RS00050	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EB231_RS00060	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EB231_RS00065	COG3300	MHYT domain
EB231_RS00065	COG5001	Diguanylate cyclase
EB231_RS00070	COG2813	Specifically methylates the guanine in position
EB231_RS00075	COG1185	polyribonucleotide nucleotidyltransferase activity
EB231_RS00080	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EB231_RS00085	COG0598	Magnesium transport protein CorA
EB231_RS00090	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EB231_RS00095	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EB231_RS00100	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EB231_RS00115	COG0779	Required for maturation of 30S ribosomal subunits
EB231_RS00125	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EB231_RS00130	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EB231_RS00135	COG1396	sequence-specific DNA binding
EB231_RS00140	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EB231_RS00150	COG1253	flavin adenine dinucleotide binding
EB231_RS00155	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EB231_RS00160	COG1702	phosphate starvation-inducible protein PhoH
EB231_RS00165	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EB231_RS00180	COG1214	PFAM Peptidase M22, glycoprotease
EB231_RS00220	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EB231_RS00225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB231_RS00250	COG0444	Belongs to the ABC transporter superfamily
EB231_RS00255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB231_RS00260	COG0601	transmembrane transport
EB231_RS00275	COG2951	lytic endotransglycosylase activity
EB231_RS00280	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EB231_RS00295	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EB231_RS00300	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EB231_RS00315	COG2816	NAD+ diphosphatase activity
EB231_RS00325	COG0077	Prephenate dehydratase
EB231_RS00325	COG1605	Chorismate mutase
EB231_RS00330	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EB231_RS00335	COG3474	cytochrome
EB231_RS00340	COG4166	transmembrane transport
EB231_RS00350	COG4174	ABC transporter (Permease)
EB231_RS00355	COG4239	(ABC) transporter, permease
EB231_RS00360	COG4172	Belongs to the ABC transporter superfamily
EB231_RS00365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EB231_RS00390	COG1793	dna ligase
EB231_RS00435	COG1595	DNA-templated transcription, initiation
EB231_RS00500	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EB231_RS00510	COG0747	negative chemotaxis
EB231_RS00515	COG0601	transmembrane transport
EB231_RS00520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB231_RS00525	COG0444	Belongs to the ABC transporter superfamily
EB231_RS00555	COG1024	Enoyl-CoA hydratase
EB231_RS00560	COG1960	acyl-CoA dehydrogenase activity
EB231_RS00570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB231_RS00575	COG3836	Belongs to the HpcH HpaI aldolase family
EB231_RS00580	COG0436	Aminotransferase
EB231_RS00585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB231_RS00595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EB231_RS00600	COG4608	Belongs to the ABC transporter superfamily
EB231_RS00605	COG0444	Belongs to the ABC transporter superfamily
EB231_RS00610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB231_RS00615	COG0601	transmembrane transport
EB231_RS00620	COG0747	negative chemotaxis
EB231_RS00630	COG2264	protein methyltransferase activity
EB231_RS00640	COG0546	phosphoglycolate phosphatase activity
EB231_RS00645	COG0166	Belongs to the GPI family
EB231_RS00650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB231_RS00675	COG0129	dihydroxy-acid dehydratase activity
EB231_RS00685	COG0489	protein tyrosine kinase activity
EB231_RS00690	COG0306	phosphate transporter
EB231_RS00695	COG1392	Phosphate transport regulator
EB231_RS00700	COG0583	DNA-binding transcription factor activity
EB231_RS00715	COG3383	formate dehydrogenase (NAD+) activity
EB231_RS00720	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EB231_RS00730	COG2197	response regulator
EB231_RS00755	COG1177	transmembrane transport
EB231_RS00760	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB231_RS00765	COG3842	ATPase activity
EB231_RS00770	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EB231_RS00780	COG1959	2 iron, 2 sulfur cluster binding
EB231_RS00785	COG3634	alkyl hydroperoxide reductase activity
EB231_RS00790	COG1349	DNA-binding transcription factor activity
EB231_RS00805	COG2226	methyltransferase
EB231_RS00815	COG0697	spore germination
EB231_RS00820	COG0402	S-adenosylhomocysteine deaminase activity
EB231_RS00825	COG1132	(ABC) transporter
EB231_RS00830	COG0129	dihydroxy-acid dehydratase activity
EB231_RS00840	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EB231_RS00845	COG0596	Alpha beta hydrolase
EB231_RS00855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB231_RS00875	COG1522	sequence-specific DNA binding
EB231_RS00880	COG0756	dUTP diphosphatase activity
EB231_RS00885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EB231_RS00915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB231_RS00925	COG0281	malic enzyme
EB231_RS00925	COG0280	phosphate acetyltransferase
EB231_RS00930	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EB231_RS00935	COG0656	L-ascorbic acid biosynthetic process
EB231_RS00965	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EB231_RS00970	COG0728	peptidoglycan biosynthetic process
EB231_RS00975	COG0180	Tryptophanyl-tRNA synthetase
EB231_RS00985	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EB231_RS00990	COG1376	ErfK ybiS ycfS ynhG family protein
EB231_RS00990	COG1388	LysM domain
EB231_RS01005	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EB231_RS01010	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EB231_RS01020	COG1643	Atp-dependent helicase
EB231_RS01040	COG1175	transmembrane transport
EB231_RS01070	COG1461	Dihydroxyacetone kinase
EB231_RS01095	COG2376	Dihydroxyacetone kinase
EB231_RS01125	COG2755	lipolytic protein G-D-S-L family
EB231_RS01125	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EB231_RS01130	COG0489	protein tyrosine kinase activity
EB231_RS01130	COG3206	protein involved in exopolysaccharide biosynthesis
EB231_RS01135	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EB231_RS01140	COG1215	transferase activity, transferring glycosyl groups
EB231_RS01145	COG1215	transferase activity, transferring glycosyl groups
EB231_RS01150	COG1215	transferase activity, transferring glycosyl groups
EB231_RS01155	COG0438	transferase activity, transferring glycosyl groups
EB231_RS01170	COG2244	polysaccharide biosynthetic process
EB231_RS01175	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EB231_RS01200	COG2273	Hydrolase Family 16
EB231_RS01210	COG1215	transferase activity, transferring glycosyl groups
EB231_RS01235	COG0367	asparagine synthase
EB231_RS01245	COG1132	(ABC) transporter
EB231_RS01255	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EB231_RS01260	COG1596	polysaccharide export
EB231_RS01265	COG3307	-O-antigen
EB231_RS01270	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS01275	COG4647	ligase activity
EB231_RS01280	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
EB231_RS01285	COG0145	ligase activity
EB231_RS01290	COG2197	response regulator
EB231_RS01300	COG0747	negative chemotaxis
EB231_RS01315	COG3395	kinase activity
EB231_RS01330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EB231_RS01335	COG4608	Belongs to the ABC transporter superfamily
EB231_RS01345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB231_RS01350	COG0601	transmembrane transport
EB231_RS01360	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS01370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EB231_RS01375	COG0438	transferase activity, transferring glycosyl groups
EB231_RS01395	COG1012	belongs to the aldehyde dehydrogenase family
EB231_RS01410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB231_RS01435	COG0431	NADPH-dependent FMN reductase
EB231_RS01450	COG1879	ABC-type sugar transport system periplasmic component
EB231_RS01455	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS01465	COG1129	ABC transporter
EB231_RS01480	COG2721	sulfolactate sulfo-lyase activity
EB231_RS01485	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS01500	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EB231_RS01505	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EB231_RS01510	COG0539	negative regulation of cytoplasmic translation
EB231_RS01540	COG4215	(ABC) transporter
EB231_RS01550	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EB231_RS01620	COG5001	Diguanylate cyclase
EB231_RS01650	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EB231_RS01655	COG1063	alcohol dehydrogenase
EB231_RS01660	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EB231_RS01665	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EB231_RS01675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EB231_RS01680	COG1609	Transcriptional regulator
EB231_RS01705	COG0523	cobalamin synthesis protein
EB231_RS01725	COG0174	glutamine synthetase
EB231_RS01735	COG1573	uracil-dna glycosylase
EB231_RS01745	COG4702	Belongs to the UPF0303 family
EB231_RS01750	COG0402	S-adenosylhomocysteine deaminase activity
EB231_RS01760	COG0583	DNA-binding transcription factor activity
EB231_RS01765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB231_RS01775	COG0384	phenazine biosynthesis protein PhzF
EB231_RS01785	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EB231_RS01795	COG2351	hydroxyisourate hydrolase activity
EB231_RS01800	COG3195	allantoin biosynthetic process
EB231_RS01800	COG3648	Uricase
EB231_RS01805	COG3257	ureidoglycine aminohydrolase activity
EB231_RS01810	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
EB231_RS01830	COG0601	transmembrane transport
EB231_RS01845	COG4166	transmembrane transport
EB231_RS01850	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EB231_RS01855	COG1595	DNA-templated transcription, initiation
EB231_RS01870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB231_RS01875	COG1609	Transcriptional regulator
EB231_RS01880	COG1653	transport
EB231_RS01885	COG1175	transmembrane transport
EB231_RS01890	COG0395	ABC-type sugar transport system, permease component
EB231_RS01895	COG0366	Alpha amylase catalytic
EB231_RS01900	COG3842	ATPase activity
EB231_RS01920	COG4638	Rieske (2fe-2S)
EB231_RS01925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EB231_RS01940	COG0463	Glycosyl transferase, family 2
EB231_RS01965	COG1652	LysM domain
EB231_RS01975	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EB231_RS01980	COG0745	RESPONSE REGULATOR receiver
EB231_RS01985	COG2205	protein histidine kinase activity
EB231_RS01990	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EB231_RS01995	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EB231_RS01995	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EB231_RS02005	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EB231_RS02010	COG2205	protein histidine kinase activity
EB231_RS02015	COG3178	'Phosphotransferase
EB231_RS02020	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EB231_RS02025	COG2887	Belongs to the helicase family. UvrD subfamily
EB231_RS02050	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EB231_RS02055	COG0159	tryptophan synthase activity
EB231_RS02060	COG0133	tryptophan synthase activity
EB231_RS02065	COG0135	phosphoribosylanthranilate isomerase activity
EB231_RS02085	COG3135	benzoate transporter
EB231_RS02095	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EB231_RS02105	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EB231_RS02110	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EB231_RS02115	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EB231_RS02125	COG0072	phenylalanine-tRNA ligase activity
EB231_RS02125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EB231_RS02135	COG0667	Aldo Keto reductase
EB231_RS02175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EB231_RS02200	COG1250	3-hydroxyacyl-CoA dehydrogenase
EB231_RS02210	COG3246	L-lysine catabolic process to acetate
EB231_RS02215	COG4977	sequence-specific DNA binding
EB231_RS02230	COG2115	Belongs to the xylose isomerase family
EB231_RS02240	COG1070	Carbohydrate kinase
EB231_RS02250	COG3468	outer membrane autotransporter barrel domain protein
EB231_RS02255	COG1280	lysine exporter protein (LysE YggA)
EB231_RS02260	COG1376	ErfK ybiS ycfS ynhG family protein
EB231_RS02260	COG1388	LysM domain
EB231_RS02265	COG0205	6-phosphofructokinase activity
EB231_RS02270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EB231_RS02280	COG1072	(Pantothenic acid kinase))
EB231_RS02285	COG0140	phosphoribosyl-ATP diphosphatase activity
EB231_RS02290	COG0107	imidazoleglycerol-phosphate synthase activity
EB231_RS02300	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EB231_RS02310	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EB231_RS02320	COG0131	Imidazoleglycerol-phosphate dehydratase
EB231_RS02325	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EB231_RS02340	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EB231_RS02370	COG1609	Transcriptional regulator
EB231_RS02385	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS02395	COG0673	inositol 2-dehydrogenase activity
EB231_RS02400	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS02405	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EB231_RS02430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB231_RS02435	COG3962	Belongs to the TPP enzyme family
EB231_RS02440	COG1082	Xylose isomerase domain protein TIM barrel
EB231_RS02450	COG3718	enzyme involved in inositol metabolism
EB231_RS02455	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EB231_RS02460	COG3454	Phosphonate metabolism
EB231_RS02465	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EB231_RS02480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB231_RS02495	COG0765	amino acid transport
EB231_RS02505	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS02510	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS02515	COG1129	ABC transporter
EB231_RS02520	COG1879	ABC-type sugar transport system periplasmic component
EB231_RS02530	COG2188	Transcriptional regulator
EB231_RS02540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EB231_RS02545	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EB231_RS02550	COG4948	Mandelate Racemase Muconate Lactonizing
EB231_RS02555	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS02560	COG3959	Transketolase, thiamine diphosphate binding domain
EB231_RS02565	COG3958	Transketolase
EB231_RS02570	COG4948	Mandelate Racemase Muconate Lactonizing
EB231_RS02575	COG1609	Transcriptional regulator
EB231_RS02580	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS02590	COG1129	ABC transporter
EB231_RS02610	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS02615	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS02630	COG1609	Transcriptional regulator
EB231_RS02645	COG2824	Alkylphosphonate utilization operon protein PhnA
EB231_RS02665	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EB231_RS02675	COG0651	ATP synthesis coupled electron transport
EB231_RS02690	COG0651	ATP synthesis coupled electron transport
EB231_RS02695	COG0649	NAD binding
EB231_RS02695	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EB231_RS02700	COG3260	NADH ubiquinone oxidoreductase 20
EB231_RS02715	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS02725	COG0673	inositol 2-dehydrogenase activity
EB231_RS02730	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS02735	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EB231_RS02745	COG1082	Xylose isomerase domain protein TIM barrel
EB231_RS02750	COG0673	inositol 2-dehydrogenase activity
EB231_RS02760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EB231_RS02765	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EB231_RS02770	COG3962	Belongs to the TPP enzyme family
EB231_RS02775	COG1414	Transcriptional regulator
EB231_RS02780	COG0673	inositol 2-dehydrogenase activity
EB231_RS02785	COG0673	inositol 2-dehydrogenase activity
EB231_RS02790	COG1879	ABC-type sugar transport system periplasmic component
EB231_RS02795	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS02800	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS02805	COG1129	ABC transporter
EB231_RS02810	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS02815	COG1609	Transcriptional regulator
EB231_RS02855	COG0583	DNA-binding transcription factor activity
EB231_RS02860	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS02875	COG1686	Belongs to the peptidase S11 family
EB231_RS02890	COG1072	(Pantothenic acid kinase))
EB231_RS02900	COG0625	glutathione transferase activity
EB231_RS02915	COG0829	nickel cation binding
EB231_RS02920	COG0831	urea catabolic process
EB231_RS02925	COG3813	Protein conserved in bacteria
EB231_RS02935	COG0832	Belongs to the urease beta subunit family
EB231_RS02950	COG0804	urea catabolic process
EB231_RS02960	COG0625	glutathione transferase activity
EB231_RS02965	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
EB231_RS02970	COG0830	nickel cation binding
EB231_RS02980	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EB231_RS02990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EB231_RS03005	COG0583	DNA-binding transcription factor activity
EB231_RS03015	COG1175	transmembrane transport
EB231_RS03050	COG3842	ATPase activity
EB231_RS03055	COG1063	alcohol dehydrogenase
EB231_RS03060	COG0395	ABC-type sugar transport system, permease component
EB231_RS03080	COG0534	Mate efflux family protein
EB231_RS03085	COG0765	amino acid transport
EB231_RS03090	COG0765	amino acid transport
EB231_RS03105	COG0583	DNA-binding transcription factor activity
EB231_RS03110	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EB231_RS03125	COG0559	Belongs to the binding-protein-dependent transport system permease family
EB231_RS03150	COG1335	isochorismatase
EB231_RS03155	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EB231_RS03180	COG1846	Transcriptional regulator
EB231_RS03185	COG1879	ABC-type sugar transport system periplasmic component
EB231_RS03190	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS03200	COG1609	Transcriptional regulator
EB231_RS03205	COG0483	inositol monophosphate 1-phosphatase activity
EB231_RS03210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB231_RS03215	COG0628	permease
EB231_RS03230	COG2076	Multidrug Resistance protein
EB231_RS03260	COG0242	peptide deformylase activity
EB231_RS03265	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EB231_RS03275	COG0101	tRNA pseudouridine synthase activity
EB231_RS03285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB231_RS03290	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EB231_RS03310	COG2171	N-acyltransferase activity
EB231_RS03325	COG3706	GGDEF domain
EB231_RS03345	COG3186	Phenylalanine-4-hydroxylase
EB231_RS03350	COG1522	sequence-specific DNA binding
EB231_RS03355	COG1032	radical SAM domain protein
EB231_RS03360	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EB231_RS03380	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EB231_RS03385	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EB231_RS03405	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EB231_RS03425	COG1566	PFAM secretion protein HlyD family protein
EB231_RS03435	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EB231_RS03440	COG0706	membrane insertase activity
EB231_RS03445	COG0594	ribonuclease P activity
EB231_RS03450	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EB231_RS03455	COG4191	Histidine kinase
EB231_RS03470	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS03495	COG3842	ATPase activity
EB231_RS03500	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB231_RS03510	COG0405	Gamma-glutamyltransferase
EB231_RS03515	COG0318	PFAM AMP-dependent synthetase and ligase
EB231_RS03520	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EB231_RS03525	COG1309	transcriptional regulator
EB231_RS03590	COG0747	negative chemotaxis
EB231_RS03625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EB231_RS03630	COG2011	ABC-type metal ion transport system permease component
EB231_RS03635	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB231_RS03640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB231_RS03670	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EB231_RS03675	COG1012	belongs to the aldehyde dehydrogenase family
EB231_RS03680	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS03685	COG0179	Fumarylacetoacetate (FAA) hydrolase
EB231_RS03695	COG0673	inositol 2-dehydrogenase activity
EB231_RS03700	COG0395	ABC-type sugar transport system, permease component
EB231_RS03705	COG1175	transmembrane transport
EB231_RS03710	COG1653	transport
EB231_RS03715	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EB231_RS03720	COG2971	BadF BadG BcrA BcrD
EB231_RS03725	COG2188	Transcriptional regulator
EB231_RS03730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EB231_RS03735	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EB231_RS03740	COG4178	(ABC) transporter
EB231_RS03745	COG0318	PFAM AMP-dependent synthetase and ligase
EB231_RS03770	COG0443	Heat shock 70 kDa protein
EB231_RS03775	COG0484	heat shock protein binding
EB231_RS03780	COG3963	phosphatidate phosphatase activity
EB231_RS03790	COG0284	orotidine-5'-phosphate decarboxylase activity
EB231_RS03800	COG0640	Transcriptional regulator
EB231_RS03825	COG3386	PFAM SMP-30 Gluconolaconase
EB231_RS03830	COG0800	Aldolase
EB231_RS03835	COG3734	2-keto-3-deoxy-galactonokinase
EB231_RS03840	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS03845	COG5001	Diguanylate cyclase
EB231_RS03865	COG0189	ligase activity
EB231_RS03885	COG0672	)-iron permease
EB231_RS03890	COG2822	iron ion transport
EB231_RS03900	COG2822	iron ion transport
EB231_RS03905	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EB231_RS03915	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EB231_RS03950	COG0076	glutamate decarboxylase activity
EB231_RS03985	COG3038	cytochrome b561
EB231_RS04005	COG0588	phosphoglycerate mutase activity
EB231_RS04010	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EB231_RS04015	COG1132	(ABC) transporter
EB231_RS04020	COG0837	glucose binding
EB231_RS04025	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
EB231_RS04035	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EB231_RS04045	COG1968	undecaprenyl-diphosphatase activity
EB231_RS04050	COG0792	nuclease activity
EB231_RS04055	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EB231_RS04080	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EB231_RS04085	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EB231_RS04095	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EB231_RS04100	COG1420	regulation of RNA biosynthetic process
EB231_RS04130	COG4941	Belongs to the sigma-70 factor family
EB231_RS04135	COG3795	YCII-related domain
EB231_RS04155	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EB231_RS04195	COG0842	Transport permease protein
EB231_RS04200	COG1131	(ABC) transporter
EB231_RS04210	COG1309	transcriptional regulator
EB231_RS04215	COG2954	triphosphatase activity
EB231_RS04245	COG2094	Belongs to the DNA glycosylase MPG family
EB231_RS04255	COG0671	phosphoesterase, PA-phosphatase related
EB231_RS04290	COG0456	acetyltransferase
EB231_RS04290	COG0454	-acetyltransferase
EB231_RS04300	COG3634	alkyl hydroperoxide reductase activity
EB231_RS04310	COG0842	Transport permease protein
EB231_RS04315	COG1131	(ABC) transporter
EB231_RS04320	COG0604	alcohol dehydrogenase
EB231_RS04330	COG1271	oxidase subunit
EB231_RS04335	COG1294	oxidase, subunit
EB231_RS04360	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EB231_RS04380	COG0481	GTPase activity
EB231_RS04400	COG0747	negative chemotaxis
EB231_RS04405	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EB231_RS04410	COG3030	protein affecting phage T7 exclusion by the F plasmid
EB231_RS04450	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EB231_RS04465	COG1959	2 iron, 2 sulfur cluster binding
EB231_RS04480	COG0626	cystathionine gamma-synthase activity
EB231_RS04500	COG0006	proline dipeptidase activity
EB231_RS04505	COG1335	isochorismatase
EB231_RS04515	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EB231_RS04520	COG0237	dephospho-CoA kinase activity
EB231_RS04525	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EB231_RS04530	COG0424	maF-like protein
EB231_RS04535	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EB231_RS04540	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EB231_RS04550	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EB231_RS04555	COG1331	Highly conserved protein containing a thioredoxin domain
EB231_RS04560	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EB231_RS04565	COG0445	tRNA wobble uridine modification
EB231_RS04570	COG0357	Ribosomal RNA small subunit methyltransferase G
EB231_RS04635	COG0642	Histidine kinase
EB231_RS04660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB231_RS04670	COG3842	ATPase activity
EB231_RS04675	COG1177	transmembrane transport
EB231_RS04680	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB231_RS04705	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EB231_RS04725	COG3964	amidohydrolase
EB231_RS04750	COG2072	flavoprotein involved in K transport
EB231_RS04755	COG1737	Transcriptional regulator
EB231_RS04760	COG1116	anion transmembrane transporter activity
EB231_RS04775	COG0673	inositol 2-dehydrogenase activity
EB231_RS04800	COG0693	protein deglycase activity
EB231_RS04820	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EB231_RS04825	COG2835	tetraacyldisaccharide 4'-kinase activity
EB231_RS04830	COG0587	DNA-directed DNA polymerase activity
EB231_RS04850	COG2301	Belongs to the HpcH HpaI aldolase family
EB231_RS04865	COG0745	RESPONSE REGULATOR receiver
EB231_RS04870	COG2205	protein histidine kinase activity
EB231_RS04880	COG1801	Protein of unknown function DUF72
EB231_RS04895	COG0640	Transcriptional regulator
EB231_RS04900	COG0066	3-isopropylmalate dehydratase activity
EB231_RS04915	COG0251	oxidation-reduction process
EB231_RS04925	COG0473	3-isopropylmalate dehydrogenase activity
EB231_RS04940	COG0513	Belongs to the DEAD box helicase family
EB231_RS04945	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EB231_RS04960	COG3781	membrane
EB231_RS04985	COG0228	four-way junction DNA binding
EB231_RS04990	COG0287	Prephenate dehydrogenase
EB231_RS04990	COG1605	Chorismate mutase
EB231_RS04995	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EB231_RS05000	COG1266	CAAX protease self-immunity
EB231_RS05030	COG0137	argininosuccinate synthase activity
EB231_RS05055	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EB231_RS05070	COG3339	Conserved Protein
EB231_RS05075	COG2154	pterin-4-alpha-carbinolamine dehydratase
EB231_RS05080	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EB231_RS05085	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EB231_RS05095	COG1136	(ABC) transporter
EB231_RS05100	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EB231_RS05105	COG0670	Belongs to the BI1 family
EB231_RS05130	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EB231_RS05140	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EB231_RS05150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EB231_RS05170	COG0431	NADPH-dependent FMN reductase
EB231_RS05180	COG2917	probably involved in intracellular septation
EB231_RS05185	COG0552	protein localization to endoplasmic reticulum
EB231_RS05190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EB231_RS05195	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EB231_RS05215	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EB231_RS05220	COG0039	L-malate dehydrogenase activity
EB231_RS05225	COG0045	succinate-CoA ligase (ADP-forming) activity
EB231_RS05240	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EB231_RS05245	COG0567	Dehydrogenase, E1 component
EB231_RS05250	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB231_RS05260	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS05275	COG4974	Belongs to the 'phage' integrase family
EB231_RS05280	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EB231_RS05285	COG0336	Belongs to the RNA methyltransferase TrmD family
EB231_RS05295	COG0335	large ribosomal subunit rRNA binding
EB231_RS05300	COG1764	response to oxidative stress
EB231_RS05305	COG1846	Transcriptional regulator
EB231_RS05315	COG0765	amino acid transport
EB231_RS05325	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EB231_RS05330	COG3706	GGDEF domain
EB231_RS05335	COG3706	GGDEF domain
EB231_RS05385	COG3132	Protein of unknown function, DUF480
EB231_RS05390	COG1764	response to oxidative stress
EB231_RS05400	COG3795	YCII-related domain
EB231_RS05415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EB231_RS05420	COG1946	Acyl-CoA thioesterase
EB231_RS05425	COG0347	Belongs to the P(II) protein family
EB231_RS05430	COG0004	ammonium transporteR
EB231_RS05440	COG2261	transglycosylase associated protein
EB231_RS05440	COG1674	ftsk spoiiie
EB231_RS05445	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EB231_RS05465	COG0745	RESPONSE REGULATOR receiver
EB231_RS05480	COG0583	DNA-binding transcription factor activity
EB231_RS05495	COG2264	protein methyltransferase activity
EB231_RS05510	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EB231_RS05515	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EB231_RS05520	COG0181	hydroxymethylbilane synthase activity
EB231_RS05545	COG0519	Catalyzes the synthesis of GMP from XMP
EB231_RS05545	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EB231_RS05550	COG1442	glycosyl transferase family 8
EB231_RS05565	COG4957	zinc ion binding
EB231_RS05580	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EB231_RS05590	COG1879	ABC-type sugar transport system periplasmic component
EB231_RS05595	COG1129	ABC transporter
EB231_RS05605	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS05610	COG1309	transcriptional regulator
EB231_RS05615	COG2814	Major facilitator Superfamily
EB231_RS05625	COG4566	intracellular signal transduction
EB231_RS05640	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB231_RS05645	COG1177	transmembrane transport
EB231_RS05650	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS05665	COG1012	belongs to the aldehyde dehydrogenase family
EB231_RS05690	COG3842	ATPase activity
EB231_RS05695	COG1177	transmembrane transport
EB231_RS05725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB231_RS05730	COG1414	Transcriptional regulator
EB231_RS05735	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EB231_RS05740	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EB231_RS05745	COG0183	Belongs to the thiolase family
EB231_RS05790	COG1120	ATPase activity
EB231_RS05800	COG0848	biopolymer transport protein
EB231_RS05845	COG1872	DUF167
EB231_RS05850	COG1737	Transcriptional regulator
EB231_RS05875	COG0395	ABC-type sugar transport system, permease component
EB231_RS05905	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EB231_RS05915	COG1704	LemA family
EB231_RS05920	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EB231_RS05925	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EB231_RS05935	COG1247	-acetyltransferase
EB231_RS05940	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EB231_RS05950	COG1309	transcriptional regulator
EB231_RS05955	COG2271	Major facilitator Superfamily
EB231_RS05995	COG2270	Major facilitator Superfamily
EB231_RS06000	COG0138	bifunctional purine biosynthesis protein purh
EB231_RS06010	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EB231_RS06010	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EB231_RS06015	COG0501	Belongs to the peptidase M48B family
EB231_RS06025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EB231_RS06040	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EB231_RS06050	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EB231_RS06055	COG5425	PFAM Usg family protein
EB231_RS06060	COG0667	Aldo Keto reductase
EB231_RS06065	COG2814	Major facilitator Superfamily
EB231_RS06070	COG0583	DNA-binding transcription factor activity
EB231_RS06075	COG0667	Aldo Keto reductase
EB231_RS06080	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EB231_RS06085	COG0495	leucyl-tRNA aminoacylation
EB231_RS06095	COG1674	ftsk spoiiie
EB231_RS06100	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EB231_RS06110	COG1794	racemase activity, acting on amino acids and derivatives
EB231_RS06120	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EB231_RS06125	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EB231_RS06130	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EB231_RS06135	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EB231_RS06140	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EB231_RS06145	COG0246	Mannitol dehydrogenase
EB231_RS06150	COG1904	glucuronate isomerase
EB231_RS06180	COG0514	ATP-dependent DNA helicase (RecQ)
EB231_RS06190	COG0477	Major facilitator Superfamily
EB231_RS06205	COG1566	PFAM secretion protein HlyD family protein
EB231_RS06225	COG3743	rRNA binding
EB231_RS06225	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EB231_RS06230	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EB231_RS06235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EB231_RS06240	COG0456	acetyltransferase
EB231_RS06250	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EB231_RS06255	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EB231_RS06260	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EB231_RS06265	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EB231_RS06285	COG0668	transmembrane transport
EB231_RS06290	COG0799	negative regulation of ribosome biogenesis
EB231_RS06295	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EB231_RS06305	COG0793	Belongs to the peptidase S41A family
EB231_RS06315	COG0494	nUDIX hydrolase
EB231_RS06320	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EB231_RS06325	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EB231_RS06335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB231_RS06375	COG1733	regulation of RNA biosynthetic process
EB231_RS06390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EB231_RS06395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB231_RS06430	COG0683	leucine binding
EB231_RS06435	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EB231_RS06440	COG3750	Belongs to the UPF0335 family
EB231_RS06455	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EB231_RS06480	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EB231_RS06485	COG1692	metallophosphoesterase
EB231_RS06490	COG0861	Integral membrane protein TerC family
EB231_RS06495	COG0217	transcriptional regulatory protein
EB231_RS06530	COG0254	rRNA binding
EB231_RS06535	COG1132	(ABC) transporter
EB231_RS06545	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EB231_RS06570	COG1272	protein, Hemolysin III
EB231_RS06575	COG0483	inositol monophosphate 1-phosphatase activity
EB231_RS06580	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EB231_RS06605	COG1522	sequence-specific DNA binding
EB231_RS06610	COG2226	methyltransferase
EB231_RS06635	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EB231_RS06640	COG0632	four-way junction helicase activity
EB231_RS06645	COG2255	four-way junction helicase activity
EB231_RS06650	COG1408	metallophosphoesterase
EB231_RS06660	COG0824	Thioesterase
EB231_RS06670	COG0848	biopolymer transport protein
EB231_RS06680	COG0823	Involved in the tonB-independent uptake of proteins
EB231_RS06690	COG2885	chlorophyll binding
EB231_RS06700	COG0037	tRNA processing
EB231_RS06705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EB231_RS06720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EB231_RS06735	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EB231_RS06740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EB231_RS06750	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EB231_RS06775	COG4143	(ABC) transporter
EB231_RS06785	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EB231_RS06800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB231_RS06805	COG0765	amino acid transport
EB231_RS06810	COG1126	abc transporter atp-binding protein
EB231_RS06815	COG1329	Transcriptional regulator
EB231_RS06820	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EB231_RS06840	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS06845	COG0183	Belongs to the thiolase family
EB231_RS06870	COG0372	Belongs to the citrate synthase family
EB231_RS06875	COG0372	Belongs to the citrate synthase family
EB231_RS06910	COG0583	DNA-binding transcription factor activity
EB231_RS06915	COG2223	nitrite transmembrane transporter activity
EB231_RS06935	COG0469	pyruvate kinase activity
EB231_RS06940	COG1376	ErfK ybiS ycfS ynhG family protein
EB231_RS06950	COG0457	Tetratricopeptide repeat
EB231_RS06955	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EB231_RS06965	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EB231_RS06990	COG1921	L-seryl-tRNASec selenium transferase activity
EB231_RS07005	COG0765	amino acid transport
EB231_RS07010	COG0765	amino acid transport
EB231_RS07035	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EB231_RS07040	COG1196	nuclear chromosome segregation
EB231_RS07040	COG0739	heme binding
EB231_RS07040	COG0741	lytic transglycosylase activity
EB231_RS07055	COG4106	trans-aconitate 2-methyltransferase activity
EB231_RS07060	COG0784	Response regulator, receiver
EB231_RS07060	COG2205	protein histidine kinase activity
EB231_RS07060	COG5002	protein histidine kinase activity
EB231_RS07065	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS07070	COG0142	geranyltranstransferase activity
EB231_RS07075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EB231_RS07080	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EB231_RS07150	COG0640	Transcriptional regulator
EB231_RS07210	COG0346	lactoylglutathione lyase activity
EB231_RS07235	COG3588	fructose-bisphosphate aldolase
EB231_RS07240	COG0126	phosphoglycerate kinase activity
EB231_RS07270	COG0450	alkyl hydroperoxide reductase
EB231_RS07275	COG3453	Protein conserved in bacteria
EB231_RS07275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EB231_RS07280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EB231_RS07285	COG0564	pseudouridine synthase activity
EB231_RS07295	COG0346	lactoylglutathione lyase activity
EB231_RS07315	COG0625	glutathione transferase activity
EB231_RS07345	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EB231_RS07350	COG0573	inorganic phosphate transmembrane transporter activity
EB231_RS07355	COG0581	inorganic phosphate transmembrane transporter activity
EB231_RS07360	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EB231_RS07365	COG0704	Plays a role in the regulation of phosphate uptake
EB231_RS07370	COG0745	RESPONSE REGULATOR receiver
EB231_RS07380	COG4213	ABC transporter substrate-binding protein
EB231_RS07385	COG4214	carbohydrate transport
EB231_RS07390	COG1129	ABC transporter
EB231_RS07415	COG2202	Pas domain
EB231_RS07415	COG3920	Histidine kinase
EB231_RS07425	COG0784	Response regulator, receiver
EB231_RS07445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EB231_RS07460	COG3920	Histidine kinase
EB231_RS07470	COG1597	lipid kinase activity
EB231_RS07485	COG0346	lactoylglutathione lyase activity
EB231_RS07490	COG0400	carboxylic ester hydrolase activity
EB231_RS07510	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB231_RS07550	COG3842	ATPase activity
EB231_RS07560	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB231_RS07570	COG0667	Aldo Keto reductase
EB231_RS07580	COG4638	Rieske (2fe-2S)
EB231_RS07590	COG2199	diguanylate cyclase activity
EB231_RS07590	COG2203	Gaf domain
EB231_RS07590	COG2200	EAL domain
EB231_RS07595	COG0745	RESPONSE REGULATOR receiver
EB231_RS07600	COG0745	RESPONSE REGULATOR receiver
EB231_RS07620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EB231_RS07635	COG3842	ATPase activity
EB231_RS07660	COG1653	transport
EB231_RS07665	COG1940	carbohydrate kinase activity
EB231_RS07665	COG1846	Transcriptional regulator
EB231_RS07670	COG0306	phosphate transporter
EB231_RS07680	COG4689	acetoacetate decarboxylase
EB231_RS07685	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS07695	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EB231_RS07705	COG3842	ATPase activity
EB231_RS07715	COG1175	transmembrane transport
EB231_RS07720	COG0395	ABC-type sugar transport system, permease component
EB231_RS07730	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EB231_RS07735	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB231_RS07735	COG0022	dehydrogenase e1 component
EB231_RS07740	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB231_RS07750	COG2390	Transcriptional regulator
EB231_RS07755	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EB231_RS07765	COG3842	ATPase activity
EB231_RS07770	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EB231_RS07795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EB231_RS07815	COG3732	PTS system glucitol sorbitol-specific
EB231_RS07835	COG2390	Transcriptional regulator
EB231_RS07845	COG1070	Carbohydrate kinase
EB231_RS07870	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS07880	COG1082	Xylose isomerase domain protein TIM barrel
EB231_RS07890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EB231_RS07895	COG4521	taurine ABC transporter
EB231_RS07900	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EB231_RS07905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB231_RS07910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB231_RS07920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EB231_RS07950	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS07955	COG0235	Class ii aldolase
EB231_RS07965	COG1129	ABC transporter
EB231_RS07970	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS07975	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS07985	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS08000	COG0579	oxidoreductase
EB231_RS08005	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EB231_RS08015	COG1942	4-Oxalocrotonate Tautomerase
EB231_RS08020	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS08025	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS08030	COG1129	ABC transporter
EB231_RS08070	COG2086	electron transfer activity
EB231_RS08080	COG0247	lactate metabolic process
EB231_RS08080	COG2181	nitrate reductase activity
EB231_RS08090	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS08100	COG1129	ABC transporter
EB231_RS08110	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS08115	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EB231_RS08120	COG3395	kinase activity
EB231_RS08125	COG1349	DNA-binding transcription factor activity
EB231_RS08135	COG1473	amidohydrolase
EB231_RS08150	COG0523	cobalamin synthesis protein
EB231_RS08155	COG0425	Belongs to the sulfur carrier protein TusA family
EB231_RS08165	COG0825	malonyl-CoA metabolic process
EB231_RS08170	COG4974	Belongs to the 'phage' integrase family
EB231_RS08180	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EB231_RS08185	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EB231_RS08190	COG4536	flavin adenine dinucleotide binding
EB231_RS08200	COG0028	Belongs to the TPP enzyme family
EB231_RS08235	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EB231_RS08240	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EB231_RS08265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EB231_RS08270	COG2226	methyltransferase
EB231_RS08275	COG4178	(ABC) transporter
EB231_RS08290	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EB231_RS08290	COG2813	Specifically methylates the guanine in position
EB231_RS08295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EB231_RS08300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EB231_RS08305	COG0287	Prephenate dehydrogenase
EB231_RS08325	COG0667	Aldo Keto reductase
EB231_RS08370	COG2884	Cell division ATP-binding protein ftsE
EB231_RS08395	COG0583	DNA-binding transcription factor activity
EB231_RS08415	COG0019	diaminopimelate decarboxylase activity
EB231_RS08425	COG0165	Argininosuccinate lyase
EB231_RS08430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EB231_RS08435	COG5001	Diguanylate cyclase
EB231_RS08435	COG3300	MHYT domain
EB231_RS08440	COG1653	transport
EB231_RS08445	COG1175	transmembrane transport
EB231_RS08455	COG3842	ATPase activity
EB231_RS08460	COG3842	ATPase activity
EB231_RS08495	COG5001	Diguanylate cyclase
EB231_RS08495	COG3447	MASE1 domain protein
EB231_RS08495	COG5002	protein histidine kinase activity
EB231_RS08500	COG1250	3-hydroxyacyl-CoA dehydrogenase
EB231_RS08505	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EB231_RS08510	COG2086	electron transfer activity
EB231_RS08530	COG0300	oxidoreductase activity
EB231_RS08540	COG0697	spore germination
EB231_RS08545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EB231_RS08565	COG1238	metal cluster binding
EB231_RS08590	COG0653	protein targeting
EB231_RS08595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EB231_RS08605	COG2814	Major facilitator Superfamily
EB231_RS08610	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EB231_RS08620	COG0494	nUDIX hydrolase
EB231_RS08635	COG2226	methyltransferase
EB231_RS08640	COG1040	competence protein
EB231_RS08650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EB231_RS08660	COG1846	Transcriptional regulator
EB231_RS08670	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EB231_RS08680	COG0527	aspartate kinase activity
EB231_RS08690	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EB231_RS08695	COG2890	protein-(glutamine-N5) methyltransferase activity
EB231_RS08705	COG0542	response to heat
EB231_RS08715	COG1376	ErfK ybiS ycfS ynhG family protein
EB231_RS08720	COG3548	integral membrane protein
EB231_RS08725	COG0477	Major facilitator Superfamily
EB231_RS08730	COG0739	heme binding
EB231_RS08765	COG3609	addiction module antidote protein, CC2985 family
EB231_RS08820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB231_RS08825	COG0842	Transport permease protein
EB231_RS08825	COG1129	ABC transporter
EB231_RS08830	COG0842	Transport permease protein
EB231_RS08840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EB231_RS08845	COG1012	belongs to the aldehyde dehydrogenase family
EB231_RS08850	COG0318	PFAM AMP-dependent synthetase and ligase
EB231_RS08875	COG0154	amidase activity
EB231_RS08880	COG0747	negative chemotaxis
EB231_RS08890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB231_RS08900	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EB231_RS08910	COG1940	carbohydrate kinase activity
EB231_RS08925	COG1879	ABC-type sugar transport system periplasmic component
EB231_RS08930	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS08935	COG1129	ABC transporter
EB231_RS08945	COG4608	Belongs to the ABC transporter superfamily
EB231_RS08955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB231_RS08960	COG0601	transmembrane transport
EB231_RS08965	COG0747	negative chemotaxis
EB231_RS08980	COG5564	TIM-barrel signal transduction protein
EB231_RS08985	COG5441	Belongs to the UPF0261 family
EB231_RS09000	COG1175	transmembrane transport
EB231_RS09015	COG3842	ATPase activity
EB231_RS09020	COG3842	ATPase activity
EB231_RS09060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EB231_RS09070	COG4948	Mandelate Racemase Muconate Lactonizing
EB231_RS09085	COG0673	inositol 2-dehydrogenase activity
EB231_RS09090	COG1082	Xylose isomerase domain protein TIM barrel
EB231_RS09095	COG3639	organic phosphonate transmembrane transporter activity
EB231_RS09100	COG3639	organic phosphonate transmembrane transporter activity
EB231_RS09110	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EB231_RS09125	COG4778	phosphonate C-P lyase system protein PhnL
EB231_RS09130	COG4107	phosphonate C-P lyase system protein PhnK
EB231_RS09135	COG3627	carbon phosphorus lyase activity
EB231_RS09140	COG0346	lactoylglutathione lyase activity
EB231_RS09145	COG3626	phosphonate metabolism
EB231_RS09150	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
EB231_RS09155	COG3624	Phosphonate C-P lyase system protein PhnG
EB231_RS09160	COG2188	Transcriptional regulator
EB231_RS09165	COG1063	alcohol dehydrogenase
EB231_RS09170	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS09175	COG1129	ABC transporter
EB231_RS09180	COG1879	ABC-type sugar transport system periplasmic component
EB231_RS09190	COG2721	sulfolactate sulfo-lyase activity
EB231_RS09195	COG1802	Transcriptional regulator
EB231_RS09205	COG2847	Copper chaperone PCu(A)C
EB231_RS09220	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EB231_RS09235	COG1175	transmembrane transport
EB231_RS09240	COG0395	ABC-type sugar transport system, permease component
EB231_RS09255	COG0673	inositol 2-dehydrogenase activity
EB231_RS09260	COG0667	Aldo Keto reductase
EB231_RS09305	COG0735	belongs to the Fur family
EB231_RS09310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EB231_RS09310	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EB231_RS09315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB231_RS09360	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS09370	COG2207	Transcriptional regulator
EB231_RS09375	COG4651	solute:proton antiporter activity
EB231_RS09375	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EB231_RS09385	COG1648	precorrin-2 dehydrogenase activity
EB231_RS09385	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EB231_RS09395	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EB231_RS09400	COG0175	sulfate reduction
EB231_RS09420	COG3239	Fatty acid desaturase
EB231_RS09430	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EB231_RS09435	COG2860	membrane
EB231_RS09445	COG0784	Response regulator, receiver
EB231_RS09445	COG5002	protein histidine kinase activity
EB231_RS09445	COG2205	protein histidine kinase activity
EB231_RS09450	COG0604	alcohol dehydrogenase
EB231_RS09455	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EB231_RS09460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EB231_RS09465	COG0116	Belongs to the methyltransferase superfamily
EB231_RS09465	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EB231_RS09470	COG2378	regulation of single-species biofilm formation
EB231_RS09485	COG2423	ornithine cyclodeaminase activity
EB231_RS09495	COG0776	regulation of translation
EB231_RS09500	COG0616	signal peptide processing
EB231_RS09510	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EB231_RS09515	COG1137	ATPase activity
EB231_RS09520	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EB231_RS09525	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EB231_RS09530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EB231_RS09545	COG1957	nucleoside hydrolase
EB231_RS09560	COG1280	lysine exporter protein (LysE YggA)
EB231_RS09565	COG0154	amidase activity
EB231_RS09570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB231_RS09600	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EB231_RS09625	COG5001	Diguanylate cyclase
EB231_RS09625	COG5002	protein histidine kinase activity
EB231_RS09650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EB231_RS09680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EB231_RS09685	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EB231_RS09690	COG2226	methyltransferase
EB231_RS09695	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EB231_RS09700	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EB231_RS09710	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EB231_RS09715	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EB231_RS09740	COG2900	Belongs to the SlyX family
EB231_RS09815	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EB231_RS09825	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EB231_RS09830	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EB231_RS09835	COG2205	protein histidine kinase activity
EB231_RS09845	COG2814	Major facilitator Superfamily
EB231_RS09865	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EB231_RS09885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB231_RS09900	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB231_RS09900	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB231_RS09920	COG0673	inositol 2-dehydrogenase activity
EB231_RS09935	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS09955	COG1960	acyl-CoA dehydrogenase activity
EB231_RS09970	COG0463	Glycosyl transferase, family 2
EB231_RS10005	COG0531	amino acid
EB231_RS10040	COG3842	ATPase activity
EB231_RS10065	COG2814	Major facilitator Superfamily
EB231_RS10080	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS10090	COG3842	ATPase activity
EB231_RS10095	COG0395	ABC-type sugar transport system, permease component
EB231_RS10100	COG1175	transmembrane transport
EB231_RS10105	COG1653	transport
EB231_RS10110	COG1012	belongs to the aldehyde dehydrogenase family
EB231_RS10115	COG1024	Enoyl-CoA hydratase
EB231_RS10130	COG1609	Transcriptional regulator
EB231_RS10145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EB231_RS10165	COG1368	sulfuric ester hydrolase activity
EB231_RS10190	COG0483	inositol monophosphate 1-phosphatase activity
EB231_RS10215	COG0071	Belongs to the small heat shock protein (HSP20) family
EB231_RS10225	COG0067	glutamate synthase
EB231_RS10225	COG0070	glutamate synthase
EB231_RS10225	COG0069	glutamate synthase activity
EB231_RS10240	COG2951	lytic endotransglycosylase activity
EB231_RS10245	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EB231_RS10265	COG0330	HflC and HflK could
EB231_RS10270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB231_RS10270	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EB231_RS10275	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EB231_RS10280	COG0737	Belongs to the 5'-nucleotidase family
EB231_RS10290	COG5310	Homospermidine synthase
EB231_RS10315	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EB231_RS10315	COG3743	rRNA binding
EB231_RS10325	COG2204	response regulator
EB231_RS10330	COG3108	Peptidase M15
EB231_RS10340	COG2207	Transcriptional regulator
EB231_RS10345	COG0300	oxidoreductase activity
EB231_RS10370	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS10375	COG3795	YCII-related domain
EB231_RS10390	COG1230	cation diffusion facilitator family transporter
EB231_RS10400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EB231_RS10415	COG0583	DNA-binding transcription factor activity
EB231_RS10420	COG0154	amidase activity
EB231_RS10470	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EB231_RS10510	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB231_RS10515	COG1177	transmembrane transport
EB231_RS10520	COG3842	ATPase activity
EB231_RS10535	COG2814	Major facilitator Superfamily
EB231_RS10545	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EB231_RS10550	COG5443	negative regulation of bacterial-type flagellum assembly
EB231_RS10570	COG1749	Flagellar hook protein flgE
EB231_RS10610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EB231_RS10615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EB231_RS10620	COG1338	Plays a role in the flagellum-specific transport system
EB231_RS10630	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EB231_RS10640	COG1706	bacterial-type flagellum-dependent cell motility
EB231_RS10645	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
EB231_RS10650	COG4786	Flagellar basal body rod
EB231_RS10655	COG1677	Flagellar hook-basal body complex protein FliE
EB231_RS10660	COG1558	bacterial-type flagellum-dependent cell motility
EB231_RS10665	COG1815	bacterial-type flagellum-dependent cell motility
EB231_RS10675	COG1157	protein secretion by the type III secretion system
EB231_RS10680	COG4786	Flagellar basal body rod
EB231_RS10690	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EB231_RS10695	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EB231_RS10700	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EB231_RS10705	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EB231_RS10710	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EB231_RS10725	COG2771	luxR family
EB231_RS10740	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EB231_RS10745	COG3842	ATPase activity
EB231_RS10750	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB231_RS10755	COG1177	transmembrane transport
EB231_RS10775	COG2183	response to ionizing radiation
EB231_RS10780	COG0583	DNA-binding transcription factor activity
EB231_RS10785	COG1960	acyl-CoA dehydrogenase activity
EB231_RS10800	COG1305	Transglutaminase-like
EB231_RS10805	COG1215	transferase activity, transferring glycosyl groups
EB231_RS10815	COG3795	YCII-related domain
EB231_RS10820	COG4941	Belongs to the sigma-70 factor family
EB231_RS10825	COG1012	belongs to the aldehyde dehydrogenase family
EB231_RS10845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EB231_RS10850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EB231_RS10860	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS10865	COG1012	belongs to the aldehyde dehydrogenase family
EB231_RS10910	COG0243	molybdopterin cofactor binding
EB231_RS10920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EB231_RS10935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EB231_RS10940	COG3707	response regulator
EB231_RS10955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EB231_RS10960	COG0583	DNA-binding transcription factor activity
EB231_RS10965	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS10970	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS11000	COG0024	Methionine aminopeptidase
EB231_RS11010	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EB231_RS11015	COG4957	zinc ion binding
EB231_RS11025	COG3706	GGDEF domain
EB231_RS11045	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EB231_RS11050	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EB231_RS11085	COG2235	arginine
EB231_RS11090	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EB231_RS11105	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EB231_RS11125	COG3038	cytochrome b561
EB231_RS11160	COG2010	Cytochrome c
EB231_RS11160	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EB231_RS11180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB231_RS11185	COG0842	Transport permease protein
EB231_RS11185	COG1129	ABC transporter
EB231_RS11190	COG0842	Transport permease protein
EB231_RS11200	COG0670	Belongs to the BI1 family
EB231_RS11230	COG1136	(ABC) transporter
EB231_RS11245	COG0673	inositol 2-dehydrogenase activity
EB231_RS11250	COG0482	sulfurtransferase activity
EB231_RS11260	COG1733	regulation of RNA biosynthetic process
EB231_RS11275	COG2201	protein-glutamate methylesterase activity
EB231_RS11320	COG0435	Glutathione S-transferase
EB231_RS11325	COG1051	belongs to the nudix hydrolase family
EB231_RS11340	COG0596	Alpha beta hydrolase
EB231_RS11340	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB231_RS11350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EB231_RS11385	COG1335	isochorismatase
EB231_RS11400	COG3180	Ammonia monooxygenase
EB231_RS11415	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS11430	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EB231_RS11435	COG0512	Glutamine amidotransferase of anthranilate synthase
EB231_RS11435	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EB231_RS11440	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EB231_RS11450	COG2814	Major facilitator Superfamily
EB231_RS11455	COG4993	Dehydrogenase
EB231_RS11465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EB231_RS11495	COG1335	isochorismatase
EB231_RS11500	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EB231_RS11535	COG0583	DNA-binding transcription factor activity
EB231_RS11540	COG0697	spore germination
EB231_RS11545	COG1435	thymidine kinase activity
EB231_RS11555	COG4176	ABC-type proline glycine betaine transport system permease component
EB231_RS11570	COG0745	RESPONSE REGULATOR receiver
EB231_RS11590	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EB231_RS11610	COG0714	Associated with various cellular activities
EB231_RS11620	COG0494	nUDIX hydrolase
EB231_RS11625	COG0617	tRNA 3'-terminal CCA addition
EB231_RS11635	COG0408	coproporphyrinogen oxidase activity
EB231_RS11645	COG0789	Transcriptional regulator
EB231_RS11650	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EB231_RS11660	COG1132	(ABC) transporter
EB231_RS11665	COG1132	(ABC) transporter
EB231_RS11695	COG2857	Cytochrome c1
EB231_RS11695	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EB231_RS11700	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EB231_RS11725	COG2233	PERMEase
EB231_RS11730	COG0402	S-adenosylhomocysteine deaminase activity
EB231_RS11740	COG0012	GTP binding
EB231_RS11745	COG0193	aminoacyl-tRNA hydrolase activity
EB231_RS11750	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EB231_RS11765	COG1846	Transcriptional regulator
EB231_RS11775	COG2223	nitrite transmembrane transporter activity
EB231_RS11780	COG2207	Transcriptional regulator
EB231_RS11785	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EB231_RS11810	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EB231_RS11830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EB231_RS11840	COG2205	protein histidine kinase activity
EB231_RS11845	COG0745	RESPONSE REGULATOR receiver
EB231_RS11850	COG1846	Transcriptional regulator
EB231_RS11855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EB231_RS11865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EB231_RS11875	COG1278	Cold shock
EB231_RS11880	COG1278	Cold shock
EB231_RS11915	COG1278	Cold shock
EB231_RS11925	COG0457	Tetratricopeptide repeat
EB231_RS11930	COG5507	3-demethylubiquinone-9 3-methyltransferase
EB231_RS11955	COG0556	nucleotide-excision repair
EB231_RS11965	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EB231_RS11985	COG0583	DNA-binding transcription factor activity
EB231_RS11990	COG2175	clavaminate synthase activity
EB231_RS12020	COG0277	FAD linked oxidase domain protein
EB231_RS12035	COG2267	carboxylic ester hydrolase activity
EB231_RS12050	COG1597	lipid kinase activity
EB231_RS12060	COG4948	Mandelate Racemase Muconate Lactonizing
EB231_RS12070	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EB231_RS12075	COG1607	acyl-coa hydrolase
EB231_RS12120	COG4941	Belongs to the sigma-70 factor family
EB231_RS12125	COG3795	YCII-related domain
EB231_RS12140	COG1253	flavin adenine dinucleotide binding
EB231_RS12175	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EB231_RS12180	COG0859	PFAM glycosyl transferase family 9
EB231_RS12190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EB231_RS12200	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EB231_RS12200	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EB231_RS12205	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EB231_RS12210	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EB231_RS12215	COG0463	Glycosyl transferase, family 2
EB231_RS12220	COG1522	sequence-specific DNA binding
EB231_RS12225	COG0492	ferredoxin-NADP+ reductase activity
EB231_RS12230	COG0583	DNA-binding transcription factor activity
EB231_RS12245	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EB231_RS12260	COG0436	Aminotransferase
EB231_RS12270	COG5001	Diguanylate cyclase
EB231_RS12270	COG3300	MHYT domain
EB231_RS12275	COG0625	glutathione transferase activity
EB231_RS12280	COG1278	Cold shock
EB231_RS12290	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EB231_RS12320	COG1295	ribonuclease BN
EB231_RS12360	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EB231_RS12380	COG2814	Major facilitator Superfamily
EB231_RS12390	COG4221	oxidoreductase activity
EB231_RS12410	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EB231_RS12415	COG1914	H( )-stimulated, divalent metal cation uptake system
EB231_RS12420	COG1321	iron dependent repressor
EB231_RS12435	COG2321	neutral zinc metallopeptidase
EB231_RS12445	COG4989	oxidoreductase activity
EB231_RS12450	COG0505	Belongs to the CarA family
EB231_RS12455	COG1610	YqeY-like protein
EB231_RS12465	COG4221	oxidoreductase activity
EB231_RS12485	COG0300	oxidoreductase activity
EB231_RS12490	COG0305	Participates in initiation and elongation during chromosome replication
EB231_RS12505	COG0789	Transcriptional regulator
EB231_RS12515	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS12520	COG0583	DNA-binding transcription factor activity
EB231_RS12525	COG2814	Major facilitator Superfamily
EB231_RS12550	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EB231_RS12580	COG1695	Transcriptional regulator
EB231_RS12605	COG4988	ABC transporter
EB231_RS12615	COG1271	oxidase subunit
EB231_RS12620	COG1294	oxidase, subunit
EB231_RS12645	COG4948	Mandelate Racemase Muconate Lactonizing
EB231_RS12665	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS12680	COG0673	inositol 2-dehydrogenase activity
EB231_RS12690	COG2223	nitrite transmembrane transporter activity
EB231_RS12695	COG1522	sequence-specific DNA binding
EB231_RS12710	COG3842	ATPase activity
EB231_RS12715	COG3246	L-lysine catabolic process to acetate
EB231_RS12725	COG1175	transmembrane transport
EB231_RS12745	COG1940	carbohydrate kinase activity
EB231_RS12750	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EB231_RS12760	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EB231_RS12785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EB231_RS12790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EB231_RS12795	COG2197	response regulator
EB231_RS12800	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS12805	COG2862	Uncharacterized protein family, UPF0114
EB231_RS12815	COG2983	Belongs to the UPF0260 family
EB231_RS12825	COG2968	Membrane
EB231_RS12840	COG3842	ATPase activity
EB231_RS12855	COG0395	ABC-type sugar transport system, permease component
EB231_RS12885	COG4948	Mandelate Racemase Muconate Lactonizing
EB231_RS12890	COG1063	alcohol dehydrogenase
EB231_RS12895	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS12905	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS12910	COG1879	ABC-type sugar transport system periplasmic component
EB231_RS12915	COG1129	ABC transporter
EB231_RS12930	COG1285	pathogenesis
EB231_RS12975	COG1376	ErfK ybiS ycfS ynhG family protein
EB231_RS12985	COG0741	lytic transglycosylase activity
EB231_RS13010	COG0154	amidase activity
EB231_RS13015	COG0583	DNA-binding transcription factor activity
EB231_RS13025	COG2423	ornithine cyclodeaminase activity
EB231_RS13030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB231_RS13035	COG0251	oxidation-reduction process
EB231_RS13040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB231_RS13045	COG0765	amino acid transport
EB231_RS13055	COG0583	DNA-binding transcription factor activity
EB231_RS13060	COG0626	cystathionine gamma-synthase activity
EB231_RS13065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB231_RS13070	COG1027	Aspartate ammonia-lyase
EB231_RS13075	COG1053	succinate dehydrogenase
EB231_RS13115	COG4221	oxidoreductase activity
EB231_RS13135	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB231_RS13140	COG0022	dehydrogenase e1 component
EB231_RS13145	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EB231_RS13150	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS13185	COG0444	Belongs to the ABC transporter superfamily
EB231_RS13195	COG0601	transmembrane transport
EB231_RS13200	COG0747	negative chemotaxis
EB231_RS13230	COG1177	transmembrane transport
EB231_RS13235	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB231_RS13245	COG3842	ATPase activity
EB231_RS13250	COG0402	S-adenosylhomocysteine deaminase activity
EB231_RS13255	COG0318	PFAM AMP-dependent synthetase and ligase
EB231_RS13260	COG2030	dehydratase
EB231_RS13265	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS13285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB231_RS13290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB231_RS13295	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EB231_RS13305	COG0683	leucine binding
EB231_RS13330	COG0145	ligase activity
EB231_RS13335	COG4172	Belongs to the ABC transporter superfamily
EB231_RS13340	COG4172	Belongs to the ABC transporter superfamily
EB231_RS13345	COG0583	DNA-binding transcription factor activity
EB231_RS13355	COG0601	transmembrane transport
EB231_RS13360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB231_RS13385	COG4608	Belongs to the ABC transporter superfamily
EB231_RS13390	COG0444	Belongs to the ABC transporter superfamily
EB231_RS13395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB231_RS13400	COG0601	transmembrane transport
EB231_RS13405	COG0747	negative chemotaxis
EB231_RS13410	COG1396	sequence-specific DNA binding
EB231_RS13420	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EB231_RS13430	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS13440	COG2376	Dihydroxyacetone kinase
EB231_RS13445	COG2376	Dihydroxyacetone kinase
EB231_RS13465	COG1175	transmembrane transport
EB231_RS13470	COG0395	ABC-type sugar transport system, permease component
EB231_RS13485	COG1349	DNA-binding transcription factor activity
EB231_RS13495	COG0583	DNA-binding transcription factor activity
EB231_RS13500	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EB231_RS13515	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
EB231_RS13525	COG3321	synthase
EB231_RS13525	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS13525	COG0604	alcohol dehydrogenase
EB231_RS13530	COG0318	PFAM AMP-dependent synthetase and ligase
EB231_RS13590	COG0583	DNA-binding transcription factor activity
EB231_RS13595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB231_RS13605	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB231_RS13605	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB231_RS13615	COG0436	Aminotransferase
EB231_RS13640	COG4608	Belongs to the ABC transporter superfamily
EB231_RS13655	COG5598	trimethylamine methyltransferase
EB231_RS13670	COG1454	alcohol dehydrogenase
EB231_RS13675	COG3485	protocatechuate 3,4-dioxygenase
EB231_RS13685	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS13695	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS13705	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS13710	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS13730	COG0473	3-isopropylmalate dehydrogenase activity
EB231_RS13740	COG1012	belongs to the aldehyde dehydrogenase family
EB231_RS13750	COG1129	ABC transporter
EB231_RS13760	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS13780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB231_RS13790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB231_RS13805	COG0154	amidase activity
EB231_RS13820	COG3454	Phosphonate metabolism
EB231_RS13830	COG5001	Diguanylate cyclase
EB231_RS13830	COG3300	MHYT domain
EB231_RS13835	COG1473	amidohydrolase
EB231_RS13865	COG2080	2 iron, 2 sulfur cluster binding
EB231_RS13865	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EB231_RS13890	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EB231_RS13905	COG2890	protein-(glutamine-N5) methyltransferase activity
EB231_RS13915	COG0318	PFAM AMP-dependent synthetase and ligase
EB231_RS13920	COG0367	asparagine synthase
EB231_RS13925	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EB231_RS13930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EB231_RS13930	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EB231_RS13950	COG4191	Histidine kinase
EB231_RS13950	COG0784	Response regulator, receiver
EB231_RS13965	COG0475	glutathione-regulated potassium exporter activity
EB231_RS13985	COG2814	Major facilitator Superfamily
EB231_RS13990	COG0583	DNA-binding transcription factor activity
EB231_RS13995	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EB231_RS14000	COG3608	succinylglutamate desuccinylase aspartoacylase
EB231_RS14005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB231_RS14015	COG0765	amino acid transport
EB231_RS14035	COG0251	oxidation-reduction process
EB231_RS14045	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EB231_RS14050	COG1869	D-ribose catabolic process
EB231_RS14070	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS14090	COG0702	epimerase
EB231_RS14105	COG0346	lactoylglutathione lyase activity
EB231_RS14130	COG5001	Diguanylate cyclase
EB231_RS14130	COG5002	protein histidine kinase activity
EB231_RS14175	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EB231_RS14180	COG0459	protein refolding
EB231_RS14190	COG0494	nUDIX hydrolase
EB231_RS14195	COG1956	GAF domain-containing protein
EB231_RS14200	COG2855	membrane
EB231_RS14220	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EB231_RS14250	COG1902	pentaerythritol trinitrate reductase activity
EB231_RS14280	COG0406	alpha-ribazole phosphatase activity
EB231_RS14320	COG0628	permease
EB231_RS14380	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB231_RS14385	COG0640	Transcriptional regulator
EB231_RS14390	COG0667	Aldo Keto reductase
EB231_RS14395	COG0583	DNA-binding transcription factor activity
EB231_RS14400	COG4251	negative regulation of phosphorylation
EB231_RS14400	COG3706	GGDEF domain
EB231_RS14400	COG2203	Gaf domain
EB231_RS14400	COG5001	Diguanylate cyclase
EB231_RS14415	COG0492	ferredoxin-NADP+ reductase activity
EB231_RS14435	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EB231_RS14480	COG1129	ABC transporter
EB231_RS14485	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS14530	COG3756	Protein conserved in bacteria
EB231_RS14550	COG0596	Alpha beta hydrolase
EB231_RS14575	COG2755	lipolytic protein G-D-S-L family
EB231_RS14575	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EB231_RS14585	COG2267	carboxylic ester hydrolase activity
EB231_RS14590	COG4106	trans-aconitate 2-methyltransferase activity
EB231_RS14630	COG0753	catalase activity
EB231_RS14640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EB231_RS14645	COG1609	Transcriptional regulator
EB231_RS14650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EB231_RS14660	COG3206	protein involved in exopolysaccharide biosynthesis
EB231_RS14660	COG0489	protein tyrosine kinase activity
EB231_RS14685	COG0297	glycogen (starch) synthase activity
EB231_RS14720	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EB231_RS14790	COG0625	glutathione transferase activity
EB231_RS14795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EB231_RS14800	COG0583	DNA-binding transcription factor activity
EB231_RS14805	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS14850	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EB231_RS14885	COG0488	(ABC) transporter
EB231_RS14925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EB231_RS14935	COG3842	ATPase activity
EB231_RS14945	COG1177	transmembrane transport
EB231_RS14950	COG4149	molybdate abc transporter
EB231_RS14960	COG0326	Molecular chaperone. Has ATPase activity
EB231_RS14985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EB231_RS14990	COG0583	DNA-binding transcription factor activity
EB231_RS15040	COG1629	transport
EB231_RS15040	COG4206	TonB-dependent receptor
EB231_RS15055	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EB231_RS15150	COG0850	regulation of cytokinetic process
EB231_RS15155	COG2894	cell division
EB231_RS15160	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EB231_RS15165	COG2205	protein histidine kinase activity
EB231_RS15170	COG0745	RESPONSE REGULATOR receiver
EB231_RS15195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB231_RS15200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EB231_RS15215	COG1846	Transcriptional regulator
EB231_RS15215	COG1940	carbohydrate kinase activity
EB231_RS15235	COG3119	arylsulfatase activity
EB231_RS15240	COG5006	permease, DMT superfamily
EB231_RS15250	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EB231_RS15255	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EB231_RS15260	COG2080	2 iron, 2 sulfur cluster binding
EB231_RS15265	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EB231_RS15270	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EB231_RS15275	COG2080	2 iron, 2 sulfur cluster binding
EB231_RS15280	COG1309	transcriptional regulator
EB231_RS15340	COG1131	(ABC) transporter
EB231_RS15370	COG0656	L-ascorbic acid biosynthetic process
EB231_RS15385	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EB231_RS15415	COG2226	methyltransferase
EB231_RS15420	COG0596	Alpha beta hydrolase
EB231_RS15435	COG0490	domain, Protein
EB231_RS15435	COG0471	metal ion transport
EB231_RS15450	COG4638	Rieske (2fe-2S)
EB231_RS15460	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS15465	COG1129	ABC transporter
EB231_RS15475	COG1082	Xylose isomerase domain protein TIM barrel
EB231_RS15480	COG0246	Mannitol dehydrogenase
EB231_RS15485	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS15495	COG0673	inositol 2-dehydrogenase activity
EB231_RS15510	COG1162	GTPase activity
EB231_RS15550	COG0596	Alpha beta hydrolase
EB231_RS15565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EB231_RS15565	COG2169	Transcriptional regulator
EB231_RS15575	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EB231_RS15575	COG2169	Transcriptional regulator
EB231_RS15600	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EB231_RS15615	COG5002	protein histidine kinase activity
EB231_RS15615	COG5001	Diguanylate cyclase
EB231_RS15640	COG0747	negative chemotaxis
EB231_RS15660	COG0583	DNA-binding transcription factor activity
EB231_RS15665	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS15670	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EB231_RS15710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB231_RS15735	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EB231_RS15750	COG1181	Belongs to the D-alanine--D-alanine ligase family
EB231_RS15755	COG1396	sequence-specific DNA binding
EB231_RS15760	COG0628	permease
EB231_RS15765	COG0454	-acetyltransferase
EB231_RS15770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EB231_RS15780	COG0745	RESPONSE REGULATOR receiver
EB231_RS15785	COG5002	protein histidine kinase activity
EB231_RS15800	COG4191	Histidine kinase
EB231_RS15800	COG0784	Response regulator, receiver
EB231_RS15820	COG0071	Belongs to the small heat shock protein (HSP20) family
EB231_RS15825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EB231_RS15830	COG0667	Aldo Keto reductase
EB231_RS15845	COG3852	Histidine kinase
EB231_RS15910	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EB231_RS16155	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EB231_RS16160	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EB231_RS16175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB231_RS16180	COG1116	anion transmembrane transporter activity
EB231_RS16225	COG1397	ADP-ribosylglycohydrolase
EB231_RS16230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB231_RS16235	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EB231_RS16245	COG1177	transmembrane transport
EB231_RS16250	COG3842	ATPase activity
EB231_RS16300	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EB231_RS16305	COG2986	histidine ammonia-lyase
EB231_RS16315	COG2814	Major facilitator Superfamily
EB231_RS16320	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS16340	COG1129	ABC transporter
EB231_RS16360	COG1175	transmembrane transport
EB231_RS16385	COG0542	response to heat
EB231_RS16395	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EB231_RS16415	COG2169	Transcriptional regulator
EB231_RS16415	COG1917	Cupin 2, conserved barrel domain protein
EB231_RS16420	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS16425	COG1129	ABC transporter
EB231_RS16435	COG2186	Transcriptional regulator
EB231_RS16445	COG1086	Polysaccharide biosynthesis protein
EB231_RS16460	COG2271	Major facilitator Superfamily
EB231_RS16465	COG1609	Transcriptional regulator
EB231_RS16475	COG1129	ABC transporter
EB231_RS16485	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS16490	COG3265	gluconokinase activity
EB231_RS16500	COG1959	2 iron, 2 sulfur cluster binding
EB231_RS16505	COG4150	thiosulfate binding
EB231_RS16520	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EB231_RS16525	COG4208	sulfate ABC transporter
EB231_RS16530	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EB231_RS16535	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EB231_RS16545	COG4953	penicillin-binding protein 1C
EB231_RS16550	COG2373	Large extracellular alpha-helical protein
EB231_RS16570	COG0601	transmembrane transport
EB231_RS16575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB231_RS16590	COG5598	trimethylamine methyltransferase
EB231_RS16640	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EB231_RS16650	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS16665	COG1309	transcriptional regulator
EB231_RS16700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB231_RS16705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB231_RS16710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EB231_RS16715	COG1522	sequence-specific DNA binding
EB231_RS16730	COG0028	Belongs to the TPP enzyme family
EB231_RS16735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EB231_RS16750	COG3706	GGDEF domain
EB231_RS16760	COG4106	trans-aconitate 2-methyltransferase activity
EB231_RS16775	COG2020	methyltransferase activity
EB231_RS16790	COG1309	transcriptional regulator
EB231_RS16805	COG0300	oxidoreductase activity
EB231_RS16810	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EB231_RS16825	COG1720	tRNA m6t6A37 methyltransferase activity
EB231_RS16885	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EB231_RS16890	COG3023	N-Acetylmuramoyl-L-alanine amidase
EB231_RS16905	COG0626	cystathionine gamma-synthase activity
EB231_RS16910	COG2001	Belongs to the MraZ family
EB231_RS16915	COG0275	rRNA processing
EB231_RS16930	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EB231_RS16940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EB231_RS16945	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EB231_RS16955	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EB231_RS16960	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EB231_RS16965	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EB231_RS16970	COG1181	Belongs to the D-alanine--D-alanine ligase family
EB231_RS16975	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EB231_RS16980	COG0849	cell division
EB231_RS16985	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EB231_RS16995	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EB231_RS17005	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EB231_RS17025	COG0006	proline dipeptidase activity
EB231_RS17035	COG2264	protein methyltransferase activity
EB231_RS17040	COG1999	signal sequence binding
EB231_RS17060	COG0300	oxidoreductase activity
EB231_RS17075	COG0534	Mate efflux family protein
EB231_RS17095	COG5598	trimethylamine methyltransferase
EB231_RS17110	COG0210	DNA helicase
EB231_RS17135	COG0784	Response regulator, receiver
EB231_RS17140	COG4191	Histidine kinase
EB231_RS17140	COG0784	Response regulator, receiver
EB231_RS17150	COG1522	sequence-specific DNA binding
EB231_RS17165	COG0277	FAD linked oxidase domain protein
EB231_RS17175	COG2837	iron assimilation
EB231_RS17225	COG2814	Major facilitator Superfamily
EB231_RS17245	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EB231_RS17260	COG3585	molybdate ion transport
EB231_RS17265	COG0725	ABC transporter, periplasmic molybdate-binding protein
EB231_RS17270	COG4149	molybdate abc transporter
EB231_RS17275	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EB231_RS17280	COG3585	molybdate ion transport
EB231_RS17280	COG2005	Transcriptional regulator
EB231_RS17300	COG0330	HflC and HflK could
EB231_RS17305	COG0330	HflC and HflK could
EB231_RS17325	COG3830	Belongs to the UPF0237 family
EB231_RS17325	COG0560	Phosphoserine phosphatase
EB231_RS17330	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EB231_RS17335	COG2199	diguanylate cyclase activity
EB231_RS17335	COG2203	Gaf domain
EB231_RS17345	COG1396	sequence-specific DNA binding
EB231_RS17365	COG2175	clavaminate synthase activity
EB231_RS17385	COG1063	alcohol dehydrogenase
EB231_RS17390	COG3284	Transcriptional regulator
EB231_RS17395	COG0028	Belongs to the TPP enzyme family
EB231_RS17405	COG0640	Transcriptional regulator
EB231_RS17420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB231_RS17450	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EB231_RS17460	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EB231_RS17465	COG3158	transport of potassium into the cell
EB231_RS17480	COG1733	regulation of RNA biosynthetic process
EB231_RS17485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EB231_RS17510	COG1309	transcriptional regulator
EB231_RS17515	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EB231_RS17540	COG1136	(ABC) transporter
EB231_RS17540	COG0577	efflux transmembrane transporter activity
EB231_RS17545	COG1136	(ABC) transporter
EB231_RS17545	COG0577	efflux transmembrane transporter activity
EB231_RS17550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB231_RS17555	COG0384	phenazine biosynthesis protein PhzF
EB231_RS17570	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EB231_RS17575	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EB231_RS17580	COG1797	cobyrinic acid a,c-diamide synthase activity
EB231_RS17645	COG3214	Protein conserved in bacteria
EB231_RS17655	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EB231_RS17660	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EB231_RS17665	COG0649	NAD binding
EB231_RS17670	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EB231_RS17675	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EB231_RS17680	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EB231_RS17680	COG3743	rRNA binding
EB231_RS17690	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EB231_RS17695	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EB231_RS17705	COG0713	ATP synthesis coupled electron transport
EB231_RS17720	COG1007	ATP synthesis coupled electron transport
EB231_RS17735	COG0346	lactoylglutathione lyase activity
EB231_RS17745	COG0442	prolyl-tRNA aminoacylation
EB231_RS17755	COG1136	(ABC) transporter
EB231_RS17770	COG0321	lipoyl(octanoyl) transferase activity
EB231_RS17780	COG2207	Transcriptional regulator
EB231_RS17800	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EB231_RS17805	COG0045	succinate-CoA ligase (ADP-forming) activity
EB231_RS17810	COG2301	Belongs to the HpcH HpaI aldolase family
EB231_RS17825	COG2239	Acts as a magnesium transporter
EB231_RS17895	COG0251	oxidation-reduction process
EB231_RS17910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB231_RS17915	COG0402	S-adenosylhomocysteine deaminase activity
EB231_RS17925	COG2249	NAD(P)H dehydrogenase (quinone) activity
EB231_RS17930	COG2249	NAD(P)H dehydrogenase (quinone) activity
EB231_RS17945	COG2040	homocysteine
EB231_RS17965	COG2814	Major facilitator Superfamily
EB231_RS17975	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB231_RS17975	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB231_RS17985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB231_RS17990	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EB231_RS17990	COG3264	Mechanosensitive ion channel
EB231_RS18010	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EB231_RS18025	COG1088	dTDP-glucose 4,6-dehydratase activity
EB231_RS18045	COG2207	Transcriptional regulator
EB231_RS18090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB231_RS18110	COG0583	DNA-binding transcription factor activity
EB231_RS18135	COG1410	methionine synthase
EB231_RS18135	COG0646	methionine synthase
EB231_RS18165	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EB231_RS18180	COG5012	cobalamin binding
EB231_RS18195	COG2186	Transcriptional regulator
EB231_RS18200	COG2807	transmembrane transport
EB231_RS18215	COG2059	Chromate
EB231_RS18225	COG2304	oxidoreductase activity
EB231_RS18235	COG0646	methionine synthase
EB231_RS18235	COG1410	methionine synthase
EB231_RS18255	COG0006	proline dipeptidase activity
EB231_RS18285	COG1505	serine-type exopeptidase activity
EB231_RS18310	COG1960	acyl-CoA dehydrogenase activity
EB231_RS18320	COG1492	cobalamin metabolic process
EB231_RS18350	COG4172	Belongs to the ABC transporter superfamily
EB231_RS18360	COG0601	transmembrane transport
EB231_RS18365	COG0747	negative chemotaxis
EB231_RS18370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB231_RS18390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EB231_RS18395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EB231_RS18400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EB231_RS18445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB231_RS18455	COG1858	cytochrome C peroxidase
EB231_RS18460	COG1522	sequence-specific DNA binding
EB231_RS18470	COG1215	transferase activity, transferring glycosyl groups
EB231_RS18500	COG3720	iron ion transport
EB231_RS18505	COG4558	Periplasmic binding protein
EB231_RS18510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EB231_RS18515	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EB231_RS18520	COG1959	2 iron, 2 sulfur cluster binding
EB231_RS18525	COG2733	membrane
EB231_RS18545	COG0477	Major facilitator Superfamily
EB231_RS18555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB231_RS18560	COG0697	spore germination
EB231_RS18575	COG2814	Major facilitator Superfamily
EB231_RS18595	COG5002	protein histidine kinase activity
EB231_RS18635	COG3142	Participates in the control of copper homeostasis
EB231_RS18650	COG1733	regulation of RNA biosynthetic process
EB231_RS18655	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS18690	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EB231_RS18710	COG0525	valine-tRNA ligase activity
EB231_RS18730	COG0129	dihydroxy-acid dehydratase activity
EB231_RS18760	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EB231_RS18765	COG0018	arginyl-trna synthetase
EB231_RS18780	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EB231_RS18785	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EB231_RS18790	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EB231_RS18795	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EB231_RS18800	COG0805	protein transport
EB231_RS18805	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EB231_RS18810	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EB231_RS18815	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EB231_RS18835	COG1862	Preprotein translocase
EB231_RS18865	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EB231_RS18895	COG0544	peptidyl-prolyl cis-trans isomerase activity
EB231_RS18905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB231_RS18910	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS18915	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS18920	COG1879	ABC-type sugar transport system periplasmic component
EB231_RS18935	COG1609	Transcriptional regulator
EB231_RS18950	COG0559	Belongs to the binding-protein-dependent transport system permease family
EB231_RS18960	COG0410	ABC transporter
EB231_RS18965	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EB231_RS18970	COG0066	3-isopropylmalate dehydratase activity
EB231_RS18975	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EB231_RS18980	COG0179	Fumarylacetoacetate (FAA) hydrolase
EB231_RS18985	COG0473	3-isopropylmalate dehydrogenase activity
EB231_RS18990	COG0583	DNA-binding transcription factor activity
EB231_RS18995	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS19005	COG0656	L-ascorbic acid biosynthetic process
EB231_RS19020	COG0583	DNA-binding transcription factor activity
EB231_RS19030	COG5002	protein histidine kinase activity
EB231_RS19070	COG0798	PFAM Bile acid sodium symporter
EB231_RS19080	COG0431	NADPH-dependent FMN reductase
EB231_RS19085	COG1609	Transcriptional regulator
EB231_RS19090	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS19095	COG3265	gluconokinase activity
EB231_RS19100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EB231_RS19105	COG1063	alcohol dehydrogenase
EB231_RS19120	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS19125	COG1129	ABC transporter
EB231_RS19135	COG0667	Aldo Keto reductase
EB231_RS19140	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS19145	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS19160	COG1879	ABC-type sugar transport system periplasmic component
EB231_RS19165	COG1129	ABC transporter
EB231_RS19170	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS19175	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS19180	COG3718	enzyme involved in inositol metabolism
EB231_RS19185	COG1609	Transcriptional regulator
EB231_RS19195	COG2003	Belongs to the UPF0758 family
EB231_RS19200	COG0024	Methionine aminopeptidase
EB231_RS19250	COG3243	poly(R)-hydroxyalkanoic acid synthase
EB231_RS19260	COG0436	Aminotransferase
EB231_RS19280	COG1494	fructose-1,6-bisphosphatase
EB231_RS19290	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EB231_RS19295	COG1752	Esterase of the alpha-beta hydrolase superfamily
EB231_RS19300	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EB231_RS19305	COG0302	gtp cyclohydrolase
EB231_RS19315	COG0583	DNA-binding transcription factor activity
EB231_RS19325	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EB231_RS19335	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EB231_RS19355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EB231_RS19370	COG2030	dehydratase
EB231_RS19385	COG0187	DNA topoisomerase II activity
EB231_RS19395	COG4964	Belongs to the GSP D family
EB231_RS19435	COG3706	GGDEF domain
EB231_RS19440	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EB231_RS19440	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EB231_RS19445	COG0509	glycine decarboxylation via glycine cleavage system
EB231_RS19450	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB231_RS19460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB231_RS19480	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EB231_RS19495	COG1671	Belongs to the UPF0178 family
EB231_RS19500	COG3791	Glutathione-dependent formaldehyde-activating
EB231_RS19505	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EB231_RS19510	COG4770	biotin carboxylase activity
EB231_RS19535	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EB231_RS19560	COG0784	Response regulator, receiver
EB231_RS19570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EB231_RS19575	COG4977	sequence-specific DNA binding
EB231_RS19585	COG2186	Transcriptional regulator
EB231_RS19590	COG0626	cystathionine gamma-synthase activity
EB231_RS19605	COG0395	ABC-type sugar transport system, permease component
EB231_RS19610	COG3842	ATPase activity
EB231_RS19615	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EB231_RS19640	COG0557	exoribonuclease II activity
EB231_RS19645	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EB231_RS19655	COG0785	Cytochrome C biogenesis protein
EB231_RS19660	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EB231_RS19665	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EB231_RS19675	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EB231_RS19685	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EB231_RS19690	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EB231_RS19695	COG3706	GGDEF domain
EB231_RS19705	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EB231_RS19735	COG5265	(ABC) transporter
EB231_RS19745	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EB231_RS19755	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EB231_RS19760	COG0281	malic enzyme
EB231_RS19760	COG0280	phosphate acetyltransferase
EB231_RS19780	COG4948	Mandelate Racemase Muconate Lactonizing
EB231_RS19790	COG1127	ABC transporter
EB231_RS19820	COG0633	Ferredoxin
EB231_RS19825	COG0492	ferredoxin-NADP+ reductase activity
EB231_RS19830	COG2814	Major facilitator Superfamily
EB231_RS19840	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EB231_RS19845	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EB231_RS19850	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EB231_RS19860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EB231_RS19860	COG0475	glutathione-regulated potassium exporter activity
EB231_RS19875	COG3768	UPF0283 membrane protein
EB231_RS19880	COG3106	COG3106 Predicted ATPase
EB231_RS19905	COG0813	purine-nucleoside phosphorylase activity
EB231_RS20000	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EB231_RS20010	COG0740	serine-type endopeptidase activity
EB231_RS20025	COG0629	single-stranded DNA binding
EB231_RS20030	COG1765	OsmC-like protein
EB231_RS20035	COG2095	MarC family integral membrane protein
EB231_RS20050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EB231_RS20050	COG2169	Transcriptional regulator
EB231_RS20065	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EB231_RS20075	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EB231_RS20095	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EB231_RS20105	COG0343	queuine tRNA-ribosyltransferase activity
EB231_RS20120	COG2308	Evidence 4 Homologs of previously reported genes of
EB231_RS20155	COG3842	ATPase activity
EB231_RS20170	COG0395	ABC-type sugar transport system, permease component
EB231_RS20185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EB231_RS20215	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EB231_RS20230	COG0071	Belongs to the small heat shock protein (HSP20) family
EB231_RS20255	COG0617	tRNA 3'-terminal CCA addition
EB231_RS20255	COG0517	IMP dehydrogenase activity
EB231_RS20255	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EB231_RS20285	COG4572	Cation transport regulator
EB231_RS20300	COG0459	protein refolding
EB231_RS20310	COG0438	transferase activity, transferring glycosyl groups
EB231_RS20335	COG0758	DNA mediated transformation
EB231_RS20340	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EB231_RS20345	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EB231_RS20350	COG0540	Belongs to the ATCase OTCase family
EB231_RS20355	COG1960	acyl-CoA dehydrogenase activity
EB231_RS20370	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EB231_RS20375	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EB231_RS20390	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EB231_RS20400	COG0154	amidase activity
EB231_RS20405	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EB231_RS20415	COG1760	l-serine dehydratase
EB231_RS20425	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EB231_RS20430	COG1686	Belongs to the peptidase S11 family
EB231_RS20440	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EB231_RS20495	COG0052	Belongs to the universal ribosomal protein uS2 family
EB231_RS20500	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EB231_RS20505	COG0583	DNA-binding transcription factor activity
EB231_RS20515	COG0667	Aldo Keto reductase
EB231_RS20520	COG0528	UMP kinase activity
EB231_RS20525	COG0233	cytoplasmic translational termination
EB231_RS20530	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EB231_RS20540	COG0750	zinc metalloprotease
EB231_RS20545	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EB231_RS20550	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EB231_RS20555	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EB231_RS20560	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EB231_RS20565	COG3494	Protein of unknown function (DUF1009)
EB231_RS20570	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EB231_RS20575	COG0372	Belongs to the citrate synthase family
EB231_RS20580	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EB231_RS20590	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EB231_RS20595	COG1802	Transcriptional regulator
EB231_RS20605	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EB231_RS20610	COG4120	Belongs to the binding-protein-dependent transport system permease family
EB231_RS20620	COG3483	tryptophan 2,3-dioxygenase activity
EB231_RS20635	COG0303	'Molybdopterin
EB231_RS20640	COG0315	cyclic pyranopterin monophosphate synthase activity
EB231_RS20645	COG0134	indole-3-glycerol-phosphate synthase activity
EB231_RS20650	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EB231_RS20655	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EB231_RS20660	COG0149	triose-phosphate isomerase activity
EB231_RS20675	COG0504	CTP synthase activity
EB231_RS20685	COG1953	Uracil, thiamine, allantoin
EB231_RS20690	COG0583	DNA-binding transcription factor activity
EB231_RS20695	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EB231_RS20700	COG2267	carboxylic ester hydrolase activity
EB231_RS20705	COG0747	negative chemotaxis
EB231_RS20710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB231_RS20720	COG0444	Belongs to the ABC transporter superfamily
EB231_RS20725	COG4608	Belongs to the ABC transporter superfamily
EB231_RS20745	COG0579	oxidoreductase
EB231_RS20775	COG1802	Transcriptional regulator
EB231_RS20805	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS20810	COG2372	response to copper ion
EB231_RS20845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EB231_RS20860	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EB231_RS20870	COG2205	protein histidine kinase activity
EB231_RS20870	COG2202	Pas domain
EB231_RS20875	COG1525	nuclease
EB231_RS20885	COG1573	uracil-dna glycosylase
EB231_RS20890	COG1522	sequence-specific DNA binding
EB231_RS20910	COG2084	Dehydrogenase
EB231_RS20925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB231_RS20930	COG1763	Mo-molybdopterin cofactor biosynthetic process
EB231_RS20935	COG0746	molybdenum cofactor guanylyltransferase activity
EB231_RS20955	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EB231_RS20970	COG1846	Transcriptional regulator
EB231_RS20985	COG1309	transcriptional regulator
EB231_RS20990	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS21020	COG0546	phosphoglycolate phosphatase activity
EB231_RS21025	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EB231_RS21040	COG2239	Acts as a magnesium transporter
EB231_RS21045	COG4178	(ABC) transporter
EB231_RS21055	COG4166	transmembrane transport
EB231_RS21070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EB231_RS21085	COG1183	phosphatidylcholine synthase activity
EB231_RS21115	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EB231_RS21120	COG0861	Integral membrane protein TerC family
EB231_RS21135	COG0596	Alpha beta hydrolase
EB231_RS21165	COG1686	Belongs to the peptidase S11 family
EB231_RS21170	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EB231_RS21180	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EB231_RS21185	COG0084	hydrolase, TatD family'
EB231_RS21190	COG1234	tRNA 3'-trailer cleavage
EB231_RS21210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EB231_RS21230	COG0670	Belongs to the BI1 family
EB231_RS21255	COG3956	TIGRFAM MazG family protein
EB231_RS21260	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EB231_RS21265	COG1923	regulation of RNA biosynthetic process
EB231_RS21270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EB231_RS21275	COG2204	response regulator
EB231_RS21280	COG5000	phosphorelay sensor kinase activity
EB231_RS21285	COG2204	response regulator
EB231_RS21290	COG3852	Histidine kinase
EB231_RS21300	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EB231_RS21300	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EB231_RS21315	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EB231_RS21325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EB231_RS21335	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB231_RS21340	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB231_RS21340	COG0022	dehydrogenase e1 component
EB231_RS21345	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EB231_RS21350	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EB231_RS21355	COG0148	phosphopyruvate hydratase activity
EB231_RS21370	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EB231_RS21385	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EB231_RS21395	COG0737	Belongs to the 5'-nucleotidase family
EB231_RS21400	COG1252	NADH dehydrogenase
EB231_RS21405	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EB231_RS21410	COG1522	sequence-specific DNA binding
EB231_RS21415	COG0686	Belongs to the AlaDH PNT family
EB231_RS21440	COG2897	thiosulfate sulfurtransferase activity
EB231_RS21445	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EB231_RS21455	COG0300	oxidoreductase activity
EB231_RS21465	COG0513	Belongs to the DEAD box helicase family
EB231_RS21470	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EB231_RS21480	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EB231_RS21480	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EB231_RS21485	COG0347	Belongs to the P(II) protein family
EB231_RS21490	COG0174	glutamine synthetase
EB231_RS21495	COG0174	glutamine synthetase
EB231_RS21520	COG0697	spore germination
EB231_RS21530	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EB231_RS21540	COG1012	belongs to the aldehyde dehydrogenase family
EB231_RS21545	COG3284	Transcriptional regulator
EB231_RS21565	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EB231_RS21575	COG0203	ribosomal protein L17
EB231_RS21580	COG0202	RNA polymerase activity
EB231_RS21585	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EB231_RS21590	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EB231_RS21595	COG0563	adenylate kinase activity
EB231_RS21605	COG0200	Binds to the 23S rRNA
EB231_RS21610	COG1841	ribosomal large subunit assembly
EB231_RS21615	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EB231_RS21620	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EB231_RS21625	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EB231_RS21630	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EB231_RS21635	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EB231_RS21640	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EB231_RS21645	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EB231_RS21650	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EB231_RS21655	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EB231_RS21660	COG0255	Belongs to the universal ribosomal protein uL29 family
EB231_RS21665	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EB231_RS21670	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EB231_RS21675	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EB231_RS21680	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EB231_RS21685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EB231_RS21690	COG0089	rRNA binding
EB231_RS21695	COG0088	Forms part of the polypeptide exit tunnel
EB231_RS21700	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EB231_RS21705	COG0051	transcription antitermination factor activity, RNA binding
EB231_RS21710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EB231_RS21715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EB231_RS21720	COG0049	tRNA binding
EB231_RS21725	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EB231_RS21740	COG4122	O-methyltransferase activity
EB231_RS21745	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EB231_RS21750	COG0085	RNA polymerase activity
EB231_RS21755	COG0222	ribosome binding
EB231_RS21760	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EB231_RS21765	COG0081	regulation of translation
EB231_RS21770	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EB231_RS21780	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EB231_RS21800	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EB231_RS21815	COG2261	transglycosylase associated protein
EB231_RS21835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EB231_RS21840	COG2084	Dehydrogenase
EB231_RS21845	COG3622	Belongs to the hyi family
EB231_RS21850	COG3960	tartronate-semialdehyde synthase activity
EB231_RS21855	COG1414	Transcriptional regulator
EB231_RS21895	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EB231_RS21905	COG4208	sulfate ABC transporter
EB231_RS21910	COG3842	ATPase activity
EB231_RS21915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EB231_RS21925	COG0154	amidase activity
EB231_RS21930	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EB231_RS21960	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EB231_RS21965	COG0513	Belongs to the DEAD box helicase family
EB231_RS21975	COG2885	chlorophyll binding
EB231_RS22000	COG0860	N-Acetylmuramoyl-L-alanine amidase
EB231_RS22005	COG1530	ribonuclease E activity
EB231_RS22010	COG2066	Belongs to the glutaminase family
EB231_RS22015	COG0436	Aminotransferase
EB231_RS22030	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EB231_RS22035	COG0511	ligase activity, forming carbon-carbon bonds
EB231_RS22045	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EB231_RS22065	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EB231_RS22070	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EB231_RS22085	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EB231_RS22090	COG3811	Belongs to the UPF0386 family
EB231_RS22095	COG0516	GMP reductase activity
EB231_RS22095	COG0517	IMP dehydrogenase activity
EB231_RS22170	COG1278	Cold shock
EB231_RS22175	COG0346	lactoylglutathione lyase activity
EB231_RS22205	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EB231_RS22225	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EB231_RS22245	COG0494	nUDIX hydrolase
EB231_RS22250	COG1902	pentaerythritol trinitrate reductase activity
EB231_RS22260	COG1177	transmembrane transport
EB231_RS22265	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB231_RS22270	COG3842	ATPase activity
EB231_RS22285	COG4566	intracellular signal transduction
EB231_RS22315	COG1546	Belongs to the CinA family
EB231_RS22315	COG1058	Belongs to the CinA family
EB231_RS22325	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EB231_RS22340	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EB231_RS22365	COG0326	Molecular chaperone. Has ATPase activity
EB231_RS22375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EB231_RS22395	COG0270	DNA (cytosine-5-)-methyltransferase activity
EB231_RS22405	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EB231_RS22490	COG0586	Pfam SNARE associated Golgi protein
EB231_RS22505	COG1968	undecaprenyl-diphosphatase activity
EB231_RS22535	COG0583	DNA-binding transcription factor activity
EB231_RS22540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB231_RS22565	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EB231_RS22570	COG3246	L-lysine catabolic process to acetate
EB231_RS22590	COG0667	Aldo Keto reductase
EB231_RS22615	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EB231_RS22620	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EB231_RS22620	COG3608	succinylglutamate desuccinylase aspartoacylase
EB231_RS22635	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EB231_RS22640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EB231_RS22650	COG3191	aminopeptidase activity
EB231_RS22670	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EB231_RS22675	COG2514	catechol 2,3-dioxygenase activity
EB231_RS22695	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EB231_RS22700	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EB231_RS22705	COG0047	phosphoribosylformylglycinamidine synthase activity
EB231_RS22730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB231_RS22740	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EB231_RS22765	COG0483	inositol monophosphate 1-phosphatase activity
EB231_RS22770	COG0037	tRNA processing
EB231_RS22775	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EB231_RS22795	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EB231_RS22800	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EB231_RS22805	COG0538	isocitrate dehydrogenase activity
EB231_RS22825	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EB231_RS22830	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EB231_RS22845	COG2313	pseudouridylate synthase activity
EB231_RS22855	COG3791	Glutathione-dependent formaldehyde-activating
EB231_RS22860	COG0316	Belongs to the HesB IscA family
EB231_RS22865	COG2151	metal-sulfur cluster biosynthetic enzyme
EB231_RS22870	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EB231_RS22875	COG0719	Fe-S assembly protein
EB231_RS22880	COG0396	ATPase activity
EB231_RS22885	COG0719	Fe-S assembly protein
EB231_RS22890	COG1104	cysteine desulfurase activity
EB231_RS22895	COG2945	thiolester hydrolase activity
EB231_RS22905	COG0671	phosphoesterase, PA-phosphatase related
EB231_RS22910	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EB231_RS22920	COG0463	Glycosyl transferase, family 2
EB231_RS22925	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EB231_RS22935	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EB231_RS22950	COG0739	heme binding
EB231_RS22955	COG1473	amidohydrolase
EB231_RS22960	COG0006	proline dipeptidase activity
EB231_RS22980	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS23075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB231_RS23085	COG3842	ATPase activity
EB231_RS23095	COG1175	transmembrane transport
EB231_RS23100	COG0395	ABC-type sugar transport system, permease component
EB231_RS23120	COG0776	regulation of translation
EB231_RS23130	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EB231_RS23135	COG0740	serine-type endopeptidase activity
EB231_RS23145	COG0076	glutamate decarboxylase activity
EB231_RS23150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB231_RS23155	COG2124	cytochrome p450
EB231_RS23180	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EB231_RS23205	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EB231_RS23210	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EB231_RS23230	COG0010	Belongs to the arginase family
EB231_RS23235	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EB231_RS23250	COG1612	heme a metabolic process
EB231_RS23290	COG0297	glycogen (starch) synthase activity
EB231_RS23315	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EB231_RS23320	COG1396	sequence-specific DNA binding
EB231_RS23365	COG0776	regulation of translation
EB231_RS23370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EB231_RS23375	COG0416	fatty acid biosynthetic process
EB231_RS23390	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EB231_RS23400	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EB231_RS23405	COG1174	glycine betaine transport
EB231_RS23410	COG1125	glycine betaine transport
EB231_RS23415	COG1174	glycine betaine transport
EB231_RS23420	COG1732	Glycine betaine
EB231_RS23425	COG2814	Major facilitator Superfamily
EB231_RS23430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EB231_RS23435	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EB231_RS23445	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EB231_RS23445	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EB231_RS23450	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EB231_RS23465	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EB231_RS23470	COG0025	NhaP-type Na H and K H
EB231_RS23475	COG2197	response regulator
EB231_RS23480	COG2989	Protein conserved in bacteria
EB231_RS23495	COG1024	Enoyl-CoA hydratase
EB231_RS23505	COG0113	porphobilinogen synthase activity
EB231_RS23520	COG0667	Aldo Keto reductase
EB231_RS23590	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EB231_RS23600	COG0628	permease
EB231_RS23605	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EB231_RS23615	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EB231_RS23625	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EB231_RS23645	COG0477	Major facilitator Superfamily
EB231_RS23650	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EB231_RS23655	COG0248	Ppx GppA phosphatase
EB231_RS23680	COG4603	Belongs to the binding-protein-dependent transport system permease family
EB231_RS23690	COG1744	ABC transporter substrate-binding protein PnrA-like
EB231_RS23710	COG1609	Transcriptional regulator
EB231_RS23720	COG3246	L-lysine catabolic process to acetate
EB231_RS23725	COG3842	ATPase activity
EB231_RS23745	COG1177	transmembrane transport
EB231_RS23750	COG1473	amidohydrolase
EB231_RS23770	COG1129	ABC transporter
EB231_RS23775	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS23780	COG4211	Belongs to the binding-protein-dependent transport system permease family
EB231_RS23795	COG3246	L-lysine catabolic process to acetate
EB231_RS23815	COG0604	alcohol dehydrogenase
EB231_RS23815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EB231_RS23815	COG3321	synthase
EB231_RS23815	COG4221	oxidoreductase activity
EB231_RS23865	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EB231_RS23870	COG1132	(ABC) transporter
EB231_RS23875	COG3459	Glycosyltransferase 36 associated
EB231_RS23885	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EB231_RS23895	COG2986	histidine ammonia-lyase
EB231_RS23900	COG1228	amidohydrolase
EB231_RS23905	COG0402	S-adenosylhomocysteine deaminase activity
EB231_RS23910	COG2188	Transcriptional regulator
EB231_RS23915	COG0251	oxidation-reduction process
EB231_RS23925	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EB231_RS23930	COG0803	Belongs to the bacterial solute-binding protein 9 family
EB231_RS23935	COG0523	cobalamin synthesis protein
EB231_RS23975	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EB231_RS23990	COG4589	Belongs to the CDS family
EB231_RS24000	COG1063	alcohol dehydrogenase
EB231_RS24015	COG0726	polysaccharide deacetylase
EB231_RS24035	COG1609	Transcriptional regulator
EB231_RS24040	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB231_RS24040	COG1902	pentaerythritol trinitrate reductase activity
EB231_RS24045	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EB231_RS24060	COG0747	negative chemotaxis
EB231_RS24065	COG5598	trimethylamine methyltransferase
EB231_RS24070	COG0583	DNA-binding transcription factor activity
EB231_RS24085	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EB231_RS24115	COG1663	tetraacyldisaccharide 4'-kinase activity
EB231_RS24120	COG1519	Transferase
EB231_RS24135	COG0483	inositol monophosphate 1-phosphatase activity
EB231_RS24140	COG0312	modulator of DNA gyrase
EB231_RS24150	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EB231_RS24185	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EB231_RS24185	COG3608	succinylglutamate desuccinylase aspartoacylase
EB231_RS24200	COG0612	Peptidase, M16
EB231_RS24205	COG0612	Peptidase, M16
EB231_RS24210	COG0742	ribosomal rna small subunit methyltransferase
EB231_RS24220	COG0590	tRNA wobble adenosine to inosine editing
EB231_RS24230	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EB231_RS24245	COG0196	riboflavin kinase activity
EB231_RS24260	COG1280	lysine exporter protein (LysE YggA)
EB231_RS24280	COG2814	Major facilitator Superfamily
EB231_RS24285	COG1566	PFAM secretion protein HlyD family protein
EB231_RS24295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EB231_RS24305	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EB231_RS24320	COG0456	acetyltransferase
EB231_RS24320	COG1846	Transcriptional regulator
EB231_RS24365	COG0459	protein refolding
EB231_RS24370	COG1309	transcriptional regulator
EB231_RS24375	COG0604	alcohol dehydrogenase
EB231_RS24380	COG1764	response to oxidative stress
EB231_RS24405	COG1280	lysine exporter protein (LysE YggA)
EB231_RS24430	COG1278	Cold shock
EB231_RS24450	COG3237	CsbD-like
EB231_RS24485	COG1309	transcriptional regulator
EB231_RS24495	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS24500	COG0114	fumarate hydratase activity
EB231_RS24505	COG2259	Doxx family
EB231_RS24520	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EB231_RS24530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EB231_RS24540	COG1126	abc transporter atp-binding protein
EB231_RS24545	COG0765	amino acid transport
EB231_RS24550	COG4597	amino acid ABC transporter
EB231_RS24555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB231_RS24560	COG0626	cystathionine gamma-synthase activity
EB231_RS24565	COG0517	IMP dehydrogenase activity
EB231_RS24570	COG1024	Enoyl-CoA hydratase
EB231_RS24585	COG0438	transferase activity, transferring glycosyl groups
EB231_RS24590	COG3706	GGDEF domain
EB231_RS24625	COG0628	permease
EB231_RS24635	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EB231_RS24640	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EB231_RS24680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB231_RS24690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EB231_RS24695	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EB231_RS24715	COG1473	amidohydrolase
EB231_RS24725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EB231_RS24730	COG1522	sequence-specific DNA binding
EB231_RS24735	COG2072	flavoprotein involved in K transport
EB231_RS24740	COG0243	molybdopterin cofactor binding
EB231_RS24745	COG0488	(ABC) transporter
EB231_RS24750	COG4957	zinc ion binding
EB231_RS24790	COG0105	UTP biosynthetic process
EB231_RS24795	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EB231_RS24800	COG0314	molybdopterin synthase activity
EB231_RS24810	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EB231_RS24815	COG0322	excinuclease ABC activity
EB231_RS24830	COG0625	glutathione transferase activity
EB231_RS24855	COG1309	transcriptional regulator
EB231_RS24880	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EB231_RS24905	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EB231_RS24930	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EB231_RS24935	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EB231_RS24940	COG0194	GDP metabolic process
EB231_RS24945	COG1561	YicC-like family, N-terminal region
EB231_RS24950	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EB231_RS24955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EB231_RS24960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EB231_RS24970	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EB231_RS24975	COG1368	sulfuric ester hydrolase activity
EB231_RS24985	COG0360	Binds together with S18 to 16S ribosomal RNA
EB231_RS24990	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EB231_RS24995	COG0359	binds to the 23S rRNA
EB231_RS25000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EB231_RS25005	COG1742	UPF0060 membrane protein
EB231_RS25030	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EB231_RS25035	COG4221	oxidoreductase activity
EB231_RS25055	COG0697	spore germination
EB231_RS25065	COG0583	DNA-binding transcription factor activity
EB231_RS25080	COG1183	phosphatidylcholine synthase activity
EB231_RS25085	COG0688	phosphatidylethanolamine metabolic process
EB231_RS25090	COG3386	PFAM SMP-30 Gluconolaconase
EB231_RS25100	COG5265	(ABC) transporter
EB231_RS25105	COG0640	Transcriptional regulator
EB231_RS25110	COG0583	DNA-binding transcription factor activity
EB231_RS25115	COG2249	NAD(P)H dehydrogenase (quinone) activity
EB231_RS25120	COG1652	LysM domain
EB231_RS25145	COG0598	Magnesium transport protein CorA
EB231_RS25155	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EB231_RS25180	COG0215	cysteine-tRNA ligase activity
EB231_RS25215	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EB231_RS25220	COG0354	folic acid binding
EB231_RS25225	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EB231_RS25230	COG5001	Diguanylate cyclase
EB231_RS25235	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS25245	COG0583	DNA-binding transcription factor activity
EB231_RS25270	COG1595	DNA-templated transcription, initiation
EB231_RS25285	COG1381	Involved in DNA repair and RecF pathway recombination
EB231_RS25300	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EB231_RS25305	COG0571	ribonuclease III activity
EB231_RS25310	COG0681	Belongs to the peptidase S26 family
EB231_RS25315	COG0736	holo-[acyl-carrier-protein] synthase activity
EB231_RS25330	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EB231_RS25340	COG1758	RNA polymerase activity
EB231_RS25360	COG1733	regulation of RNA biosynthetic process
EB231_RS25370	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EB231_RS25375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EB231_RS25380	COG0741	lytic transglycosylase activity
EB231_RS25410	COG0457	Tetratricopeptide repeat
EB231_RS25415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EB231_RS25420	COG1846	Transcriptional regulator
EB231_RS25420	COG0456	acetyltransferase
EB231_RS25425	COG1254	Belongs to the acylphosphatase family
EB231_RS25435	COG1960	acyl-CoA dehydrogenase activity
EB231_RS25440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EB231_RS25445	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EB231_RS25490	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EB231_RS25535	COG0308	aminopeptidase N
EB231_RS25540	COG2205	protein histidine kinase activity
EB231_RS25540	COG2202	Pas domain
EB231_RS25550	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EB231_RS25560	COG0745	RESPONSE REGULATOR receiver
EB231_RS25565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EB231_RS25570	COG3088	subunit of a heme lyase
EB231_RS25575	COG1138	Cytochrome C-type biogenesis protein
EB231_RS25580	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EB231_RS25585	COG4235	cytochrome complex assembly
EB231_RS25600	COG0745	RESPONSE REGULATOR receiver
EB231_RS25635	COG3842	ATPase activity
EB231_RS25655	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EB231_RS25685	COG3409	Peptidoglycan-binding domain 1 protein
EB231_RS25685	COG3429	Glucose-6-phosphate dehydrogenase subunit
EB231_RS25690	COG2205	protein histidine kinase activity
EB231_RS25700	COG2166	iron-sulfur cluster assembly
EB231_RS25720	COG1280	lysine exporter protein (LysE YggA)
EB231_RS25730	COG2010	Cytochrome c
EB231_RS25740	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EB231_RS25745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EB231_RS25755	COG1376	ErfK ybiS ycfS ynhG family protein
EB231_RS25760	COG0433	COG0433 Predicted ATPase
EB231_RS25780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EB231_RS25795	COG0183	Belongs to the thiolase family
EB231_RS25800	COG1309	transcriptional regulator
EB231_RS25805	COG3119	arylsulfatase activity
EB231_RS25815	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EB231_RS25820	COG1012	belongs to the aldehyde dehydrogenase family
EB231_RS25865	COG4172	Belongs to the ABC transporter superfamily
EB231_RS25870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB231_RS25875	COG0601	transmembrane transport
EB231_RS25880	COG4166	transmembrane transport
EB231_RS25895	COG0366	Alpha amylase catalytic
EB231_RS25900	COG1523	belongs to the glycosyl hydrolase 13 family
EB231_RS25905	COG0033	Phosphoglucomutase
EB231_RS25910	COG0297	glycogen (starch) synthase activity
EB231_RS25915	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EB231_RS25920	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EB231_RS25925	COG0058	SHG alpha-glucan phosphorylase activity
EB231_RS25965	COG1218	3'(2'),5'-bisphosphate nucleotidase
EB231_RS25975	COG0175	sulfate reduction
EB231_RS25990	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EB231_RS26000	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EB231_RS26040	COG2226	methyltransferase
EB231_RS26060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EB231_RS26075	COG2076	Multidrug Resistance protein
EB231_RS26100	COG1091	dTDP-4-dehydrorhamnose reductase activity
EB231_RS26110	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
EB231_RS26125	COG1268	BioY protein
EB231_RS26165	COG0574	Belongs to the PEP-utilizing enzyme family
EB231_RS26165	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EB231_RS26195	COG0583	DNA-binding transcription factor activity
EB231_RS26200	COG0747	negative chemotaxis
EB231_RS26210	COG1196	nuclear chromosome segregation
EB231_RS26215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EB231_RS26225	COG1194	a g-specific adenine glycosylase
EB231_RS26235	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EB231_RS26240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EB231_RS26255	COG0612	Peptidase, M16
EB231_RS26260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EB231_RS26270	COG1678	Uncharacterized ACR, COG1678
EB231_RS26280	COG0678	peroxiredoxin activity
EB231_RS26295	COG0328	RNA-DNA hybrid ribonuclease activity
EB231_RS26300	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EB231_RS26305	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EB231_RS26310	COG3346	SURF1 family
EB231_RS26330	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EB231_RS26340	COG0109	protoheme IX farnesyltransferase activity
EB231_RS26345	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EB231_RS26350	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EB231_RS26350	COG1565	acr, cog1565
EB231_RS26360	COG0312	modulator of DNA gyrase
EB231_RS26385	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EB231_RS26405	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EB231_RS26410	COG1741	Belongs to the pirin family
EB231_RS26420	COG1722	exodeoxyribonuclease VII activity
EB231_RS26425	COG0123	including yeast histone deacetylase and acetoin utilization protein
EB231_RS26430	COG0778	Nitroreductase
EB231_RS26440	COG1309	transcriptional regulator
EB231_RS26450	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EB231_RS26450	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EB231_RS26455	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EB231_RS26470	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EB231_RS26485	COG0259	pyridoxamine-phosphate oxidase activity
EB231_RS26490	COG1024	Enoyl-CoA hydratase
EB231_RS26495	COG1960	acyl-CoA dehydrogenase activity
EB231_RS26520	COG0151	Belongs to the GarS family
EB231_RS26530	COG0583	DNA-binding transcription factor activity
EB231_RS26535	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EB231_RS26545	COG0277	FAD linked oxidase domain protein
EB231_RS26550	COG0009	L-threonylcarbamoyladenylate synthase
EB231_RS26570	COG0751	glycine-tRNA ligase activity
EB231_RS26580	COG0752	glycyl-tRNA synthetase alpha subunit
EB231_RS26605	COG0142	geranyltranstransferase activity
EB231_RS26630	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EB231_RS26635	COG0521	Mo-molybdopterin cofactor biosynthetic process
EB231_RS26650	COG0463	Glycosyl transferase, family 2
EB231_RS26660	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EB231_RS26665	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EB231_RS26670	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EB231_RS26675	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EB231_RS26680	COG0356	it plays a direct role in the translocation of protons across the membrane
EB231_RS26695	COG2814	Major facilitator Superfamily
EB231_RS26700	COG0583	DNA-binding transcription factor activity
EB231_RS26705	COG1160	GTP binding
EB231_RS26710	COG2976	Protein conserved in bacteria
EB231_RS26720	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EB231_RS26725	COG0477	Major facilitator Superfamily
EB231_RS26735	COG0583	DNA-binding transcription factor activity
EB231_RS26740	COG2309	aminopeptidase activity
EB231_RS26750	COG1393	Belongs to the ArsC family
EB231_RS26770	COG3842	ATPase activity
EB231_RS26785	COG1177	transmembrane transport
EB231_RS26790	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB231_RS26810	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS26825	COG1309	transcriptional regulator
EB231_RS26835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB231_RS26840	COG0583	DNA-binding transcription factor activity
EB231_RS26855	COG4948	Mandelate Racemase Muconate Lactonizing
EB231_RS26860	COG4948	Mandelate Racemase Muconate Lactonizing
EB231_RS26865	COG0747	negative chemotaxis
EB231_RS26875	COG0601	transmembrane transport
EB231_RS26895	COG0747	negative chemotaxis
EB231_RS26910	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS26920	COG2113	Glycine betaine
EB231_RS26925	COG4175	Glycine betaine
EB231_RS26930	COG4176	ABC-type proline glycine betaine transport system permease component
EB231_RS26960	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB231_RS26980	COG0531	amino acid
EB231_RS26995	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EB231_RS27000	COG2218	PFAM glutamate synthase alpha subunit domain protein
EB231_RS27005	COG0069	glutamate synthase activity
EB231_RS27015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB231_RS27020	COG4311	Sarcosine oxidase, delta subunit
EB231_RS27025	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB231_RS27025	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB231_RS27035	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EB231_RS27065	COG0318	PFAM AMP-dependent synthetase and ligase
EB231_RS27075	COG3347	Dehydrogenase
EB231_RS27075	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS27090	COG1129	ABC transporter
EB231_RS27095	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EB231_RS27100	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EB231_RS27115	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EB231_RS27120	COG2376	Dihydroxyacetone kinase
EB231_RS27125	COG1461	Dihydroxyacetone kinase
EB231_RS27140	COG0698	ribose 5-phosphate isomerase
EB231_RS27145	COG0149	triose-phosphate isomerase activity
EB231_RS27175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EB231_RS27185	COG3842	ATPase activity
EB231_RS27200	COG1175	transmembrane transport
EB231_RS27205	COG1653	transport
EB231_RS27215	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EB231_RS27230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EB231_RS27240	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS27270	COG0174	glutamine synthetase
EB231_RS27280	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EB231_RS27290	COG2204	response regulator
EB231_RS27295	COG4191	Histidine kinase
EB231_RS27300	COG1301	dicarboxylic acid transport
EB231_RS27310	COG1940	carbohydrate kinase activity
EB231_RS27315	COG0516	GMP reductase activity
EB231_RS27330	COG0673	inositol 2-dehydrogenase activity
EB231_RS27340	COG0395	ABC-type sugar transport system, permease component
EB231_RS27350	COG1653	transport
EB231_RS27355	COG0673	inositol 2-dehydrogenase activity
EB231_RS27370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB231_RS27375	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
EB231_RS27395	COG2268	Band 7 protein
EB231_RS27395	COG2268	Band 7 protein
EB231_RS27400	COG5441	Belongs to the UPF0261 family
EB231_RS27420	COG0559	Belongs to the binding-protein-dependent transport system permease family
EB231_RS27430	COG0596	Alpha beta hydrolase
EB231_RS27435	COG0179	Fumarylacetoacetate (FAA) hydrolase
EB231_RS27440	COG2186	Transcriptional regulator
EB231_RS27455	COG3485	protocatechuate 3,4-dioxygenase
EB231_RS27460	COG3485	protocatechuate 3,4-dioxygenase
EB231_RS27465	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EB231_RS27470	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EB231_RS27475	COG0583	DNA-binding transcription factor activity
EB231_RS27510	COG3842	ATPase activity
EB231_RS27515	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB231_RS27520	COG1177	transmembrane transport
EB231_RS27525	COG0277	FAD linked oxidase domain protein
EB231_RS27540	COG0667	Aldo Keto reductase
EB231_RS27570	COG0559	Belongs to the binding-protein-dependent transport system permease family
EB231_RS27580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB231_RS27585	COG1802	Transcriptional regulator
EB231_RS27590	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EB231_RS27600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB231_RS27665	COG0823	Involved in the tonB-independent uptake of proteins
EB231_RS27665	COG4946	Tricorn protease homolog
EB231_RS27665	COG1506	peptidase
EB231_RS27680	COG0601	transmembrane transport
EB231_RS27690	COG0444	Belongs to the ABC transporter superfamily
EB231_RS27695	COG4608	Belongs to the ABC transporter superfamily
EB231_RS27705	COG0583	DNA-binding transcription factor activity
EB231_RS27725	COG2706	6-phosphogluconolactonase activity
EB231_RS27750	COG1129	ABC transporter
EB231_RS27755	COG1129	ABC transporter
EB231_RS27760	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS27785	COG1175	transmembrane transport
EB231_RS27790	COG0395	ABC-type sugar transport system, permease component
EB231_RS27795	COG3842	ATPase activity
EB231_RS27800	COG4948	Mandelate Racemase Muconate Lactonizing
EB231_RS27805	COG3254	rhamnose metabolic process
EB231_RS27840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EB231_RS27850	COG1012	belongs to the aldehyde dehydrogenase family
EB231_RS27860	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EB231_RS27865	COG0583	DNA-binding transcription factor activity
EB231_RS27875	COG1349	DNA-binding transcription factor activity
EB231_RS27885	COG3608	succinylglutamate desuccinylase aspartoacylase
EB231_RS27890	COG0006	proline dipeptidase activity
EB231_RS27895	COG2423	ornithine cyclodeaminase activity
EB231_RS27900	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EB231_RS27910	COG0765	amino acid transport
EB231_RS27915	COG0765	amino acid transport
EB231_RS27920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB231_RS27925	COG1126	abc transporter atp-binding protein
EB231_RS27930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB231_RS27935	COG1522	sequence-specific DNA binding
EB231_RS27940	COG1012	belongs to the aldehyde dehydrogenase family
EB231_RS27945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EB231_RS27950	COG0604	alcohol dehydrogenase
EB231_RS27950	COG3321	synthase
EB231_RS27950	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS27955	COG2986	histidine ammonia-lyase
EB231_RS27975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EB231_RS27980	COG1132	(ABC) transporter
EB231_RS27985	COG1132	(ABC) transporter
EB231_RS27995	COG0477	Major facilitator Superfamily
EB231_RS28030	COG1063	alcohol dehydrogenase
EB231_RS28035	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EB231_RS28040	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS28045	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EB231_RS28050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB231_RS28055	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EB231_RS28070	COG2084	Dehydrogenase
EB231_RS28085	COG0251	oxidation-reduction process
EB231_RS28090	COG2186	Transcriptional regulator
EB231_RS28100	COG4221	oxidoreductase activity
EB231_RS28105	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS28115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB231_RS28120	COG4597	amino acid ABC transporter
EB231_RS28125	COG0765	amino acid transport
EB231_RS28130	COG1126	abc transporter atp-binding protein
EB231_RS28135	COG0277	FAD linked oxidase domain protein
EB231_RS28140	COG0028	Belongs to the TPP enzyme family
EB231_RS28155	COG0436	Aminotransferase
EB231_RS28160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EB231_RS28170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EB231_RS28190	COG0747	negative chemotaxis
EB231_RS28195	COG0583	DNA-binding transcription factor activity
EB231_RS28205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EB231_RS28210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EB231_RS28215	COG5598	trimethylamine methyltransferase
EB231_RS28220	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EB231_RS28225	COG1335	isochorismatase
EB231_RS28255	COG0251	oxidation-reduction process
EB231_RS28265	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS28295	COG0386	Belongs to the glutathione peroxidase family
EB231_RS28300	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS28305	COG3591	Belongs to the peptidase S1B family
EB231_RS28305	COG1864	DNA RNA non-specific endonuclease
EB231_RS28390	COG2885	chlorophyll binding
EB231_RS28445	COG3501	Rhs element vgr protein
EB231_RS28455	COG2885	chlorophyll binding
EB231_RS28480	COG0739	heme binding
EB231_RS28525	COG0459	protein refolding
EB231_RS28540	COG1063	alcohol dehydrogenase
EB231_RS28555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EB231_RS28560	COG3350	monooxygenase activity
EB231_RS28595	COG2235	arginine
EB231_RS28635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB231_RS28700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB231_RS28710	COG2188	Transcriptional regulator
EB231_RS28725	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS28765	COG1879	ABC-type sugar transport system periplasmic component
EB231_RS28770	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS28775	COG1129	ABC transporter
EB231_RS28785	COG1454	alcohol dehydrogenase
EB231_RS28800	COG1012	belongs to the aldehyde dehydrogenase family
EB231_RS28805	COG0583	DNA-binding transcription factor activity
EB231_RS28820	COG2268	Band 7 protein
EB231_RS28835	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS28850	COG1129	ABC transporter
EB231_RS28855	COG1879	ABC-type sugar transport system periplasmic component
EB231_RS28860	COG2205	protein histidine kinase activity
EB231_RS28870	COG3386	PFAM SMP-30 Gluconolaconase
EB231_RS28875	COG1012	belongs to the aldehyde dehydrogenase family
EB231_RS28880	COG1012	belongs to the aldehyde dehydrogenase family
EB231_RS28885	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EB231_RS28900	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS28905	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS28910	COG1129	ABC transporter
EB231_RS28915	COG1879	ABC-type sugar transport system periplasmic component
EB231_RS28930	COG2181	nitrate reductase activity
EB231_RS28930	COG0247	lactate metabolic process
EB231_RS29000	COG4191	Histidine kinase
EB231_RS29000	COG0784	Response regulator, receiver
EB231_RS29005	COG0640	Transcriptional regulator
EB231_RS29060	COG0640	Transcriptional regulator
EB231_RS29110	COG3920	Histidine kinase
EB231_RS29120	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EB231_RS29130	COG1285	pathogenesis
EB231_RS29175	COG4187	Peptidase family M20/M25/M40
EB231_RS29180	COG1793	dna ligase
EB231_RS29185	COG3685	Protein conserved in bacteria
EB231_RS29245	COG0438	transferase activity, transferring glycosyl groups
EB231_RS29295	COG0765	amino acid transport
EB231_RS29300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB231_RS29330	COG0765	amino acid transport
EB231_RS29335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB231_RS29340	COG0583	DNA-binding transcription factor activity
EB231_RS29350	COG0583	DNA-binding transcription factor activity
EB231_RS29355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EB231_RS29370	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS29375	COG2267	carboxylic ester hydrolase activity
EB231_RS29400	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EB231_RS29410	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS29415	COG1129	ABC transporter
EB231_RS29425	COG1802	Transcriptional regulator
EB231_RS29435	COG3386	PFAM SMP-30 Gluconolaconase
EB231_RS29440	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB231_RS29450	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EB231_RS29455	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS29460	COG2197	response regulator
EB231_RS29465	COG3916	Acyl-homoserine-lactone synthase
EB231_RS29470	COG0583	DNA-binding transcription factor activity
EB231_RS29480	COG2948	multi-organism process
EB231_RS29510	COG3451	type IV secretory pathway VirB4
EB231_RS29520	COG3838	Conjugal transfer protein Trbc
EB231_RS29525	COG4962	Type ii secretion system protein e
EB231_RS29545	COG5642	Protein of unknown function (DUF2384)
EB231_RS29635	COG4957	zinc ion binding
EB231_RS29640	COG5489	Protein of unknown function (DUF736)
EB231_RS29695	COG0587	DNA-directed DNA polymerase activity
EB231_RS29745	COG1024	Enoyl-CoA hydratase
EB231_RS29755	COG1960	acyl-CoA dehydrogenase activity
EB231_RS29760	COG2050	protein possibly involved in aromatic compounds catabolism
EB231_RS29765	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS29770	COG1473	amidohydrolase
EB231_RS29780	COG0582	viral genome integration into host DNA
EB231_RS29785	COG0519	Catalyzes the synthesis of GMP from XMP
EB231_RS29785	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EB231_RS29800	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EB231_RS29805	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EB231_RS29805	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EB231_RS29810	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EB231_RS29815	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EB231_RS29830	COG0765	amino acid transport
EB231_RS29865	COG0387	Pfam Sodium calcium exchanger
EB231_RS29870	COG0318	PFAM AMP-dependent synthetase and ligase
EB231_RS29875	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EB231_RS29880	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EB231_RS29885	COG0124	histidyl-tRNA synthetase
EB231_RS29900	COG2818	Glycosylase
EB231_RS29905	COG1376	ErfK ybiS ycfS ynhG family protein
EB231_RS29910	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EB231_RS29915	COG0247	lactate metabolic process
EB231_RS29920	COG0277	FAD linked oxidase domain protein
EB231_RS29925	COG0277	FAD linked oxidase domain protein
EB231_RS29935	COG2186	Transcriptional regulator
EB231_RS29980	COG0583	DNA-binding transcription factor activity
EB231_RS29985	COG1570	exodeoxyribonuclease VII activity
EB231_RS30015	COG2808	Putative FMN-binding domain
EB231_RS30040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB231_RS30045	COG0837	glucose binding
EB231_RS30045	COG1737	Transcriptional regulator
EB231_RS30055	COG0174	glutamine synthetase
EB231_RS30070	COG0277	FAD linked oxidase domain protein
EB231_RS30075	COG1312	Catalyzes the dehydration of D-mannonate
EB231_RS30080	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS30095	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS30100	COG3769	mannosylglycerate metabolic process
EB231_RS30130	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EB231_RS30145	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EB231_RS30150	COG1845	cytochrome c oxidase, subunit III
EB231_RS30155	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EB231_RS30160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EB231_RS30165	COG0477	Major facilitator Superfamily
EB231_RS30185	COG1376	ErfK ybiS ycfS ynhG family protein
EB231_RS30195	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EB231_RS30205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB231_RS30210	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
EB231_RS30220	COG1596	polysaccharide export
EB231_RS30230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EB231_RS30235	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EB231_RS30245	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EB231_RS30270	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EB231_RS30285	COG0367	asparagine synthase
EB231_RS30320	COG1012	belongs to the aldehyde dehydrogenase family
EB231_RS30345	COG1177	transmembrane transport
EB231_RS30350	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB231_RS30375	COG4214	carbohydrate transport
EB231_RS30400	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EB231_RS30405	COG4172	Belongs to the ABC transporter superfamily
EB231_RS30430	COG1349	DNA-binding transcription factor activity
EB231_RS30445	COG0183	Belongs to the thiolase family
EB231_RS30450	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS30455	COG0318	PFAM AMP-dependent synthetase and ligase
EB231_RS30460	COG1129	ABC transporter
EB231_RS30470	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS30480	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS30495	COG3842	ATPase activity
EB231_RS30500	COG2235	arginine
EB231_RS30505	COG1177	transmembrane transport
EB231_RS30510	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB231_RS30520	COG1609	Transcriptional regulator
EB231_RS30550	COG1653	transport
EB231_RS30565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB231_RS30575	COG0434	BtpA family
EB231_RS30600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB231_RS30645	COG1473	amidohydrolase
EB231_RS30650	COG3842	ATPase activity
EB231_RS30665	COG1175	transmembrane transport
EB231_RS30680	COG0667	Aldo Keto reductase
EB231_RS30685	COG4948	Mandelate Racemase Muconate Lactonizing
EB231_RS30690	COG1090	epimerase
EB231_RS30695	COG4948	Mandelate Racemase Muconate Lactonizing
EB231_RS30705	COG4948	Mandelate Racemase Muconate Lactonizing
EB231_RS30710	COG4948	Mandelate Racemase Muconate Lactonizing
EB231_RS30720	COG1653	transport
EB231_RS30735	COG3842	ATPase activity
EB231_RS30740	COG4948	Mandelate Racemase Muconate Lactonizing
EB231_RS30760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EB231_RS30780	COG2197	response regulator
EB231_RS30790	COG0438	transferase activity, transferring glycosyl groups
EB231_RS30810	COG1596	polysaccharide export
EB231_RS30825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EB231_RS30890	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EB231_RS30895	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EB231_RS30895	COG2755	lipolytic protein G-D-S-L family
EB231_RS30900	COG2755	lipolytic protein G-D-S-L family
EB231_RS30900	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EB231_RS30915	COG0726	polysaccharide deacetylase
EB231_RS30960	COG5490	Phasin protein
EB231_RS30965	COG2205	protein histidine kinase activity
EB231_RS30970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EB231_RS30980	COG1177	transmembrane transport
EB231_RS30985	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB231_RS30990	COG3842	ATPase activity
EB231_RS31010	COG2224	Isocitrate lyase
EB231_RS31030	COG0174	glutamine synthetase
EB231_RS31035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB231_RS31050	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EB231_RS31055	COG0363	glucosamine-6-phosphate deaminase activity
EB231_RS31060	COG0129	dihydroxy-acid dehydratase activity
EB231_RS31065	COG2304	oxidoreductase activity
EB231_RS31080	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EB231_RS31100	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EB231_RS31130	COG3775	system Galactitol-specific IIC component
EB231_RS31150	COG0596	Alpha beta hydrolase
EB231_RS31175	COG4177	L-phenylalanine transmembrane transporter activity
EB231_RS31180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB231_RS31200	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EB231_RS31240	COG4964	Belongs to the GSP D family
EB231_RS31290	COG2274	protein secretion by the type I secretion system
EB231_RS31350	COG0667	Aldo Keto reductase
EB231_RS31370	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EB231_RS31380	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EB231_RS31385	COG5328	Belongs to the UPF0262 family
EB231_RS31395	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EB231_RS31400	COG0424	maF-like protein
EB231_RS31405	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EB231_RS31425	COG1129	ABC transporter
EB231_RS31430	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS31435	COG1486	melibiose metabolic process
EB231_RS31445	COG0582	viral genome integration into host DNA
EB231_RS31450	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EB231_RS31495	COG3177	Filamentation induced by cAMP protein fic
EB231_RS31525	COG2010	Cytochrome c
EB231_RS31555	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EB231_RS31565	COG2948	multi-organism process
EB231_RS31590	COG3451	type IV secretory pathway VirB4
EB231_RS31600	COG3838	Conjugal transfer protein Trbc
EB231_RS31605	COG4962	Type ii secretion system protein e
EB231_RS31635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EB231_RS31650	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EB231_RS31655	COG3916	Acyl-homoserine-lactone synthase
EB231_RS31675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EB231_RS31750	COG0745	RESPONSE REGULATOR receiver
EB231_RS31755	COG4372	Transposase
EB231_RS31800	COG1304	FMN binding
EB231_RS31810	COG1657	PFAM Prenyltransferase squalene oxidase
EB231_RS31815	COG0142	geranyltranstransferase activity
EB231_RS31820	COG2124	cytochrome p450
EB231_RS31825	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS31830	COG2124	cytochrome p450
EB231_RS31835	COG2124	cytochrome p450
EB231_RS31865	COG0583	DNA-binding transcription factor activity
EB231_RS31870	COG1129	ABC transporter
EB231_RS31875	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS31880	COG1879	ABC-type sugar transport system periplasmic component
EB231_RS31885	COG3618	amidohydrolase
EB231_RS31890	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS31895	COG3959	Transketolase, thiamine diphosphate binding domain
EB231_RS31900	COG3958	Transketolase
EB231_RS31950	COG1472	Belongs to the glycosyl hydrolase 3 family
EB231_RS31995	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
EB231_RS32005	COG4245	von Willebrand factor, type A
EB231_RS32025	COG0464	growth
EB231_RS32045	COG1472	Belongs to the glycosyl hydrolase 3 family
EB231_RS32055	COG1525	nuclease
EB231_RS32075	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EB231_RS32095	COG4959	Type IV secretory pathway protease TraF
EB231_RS32125	COG0583	DNA-binding transcription factor activity
EB231_RS32130	COG3153	acetyltransferase
EB231_RS32135	COG3594	Acyltransferase
EB231_RS32145	COG0583	DNA-binding transcription factor activity
EB231_RS32165	COG0726	polysaccharide deacetylase
EB231_RS32185	COG2192	nodulation
EB231_RS32195	COG1131	(ABC) transporter
EB231_RS32200	COG1215	transferase activity, transferring glycosyl groups
EB231_RS32205	COG3153	acetyltransferase
EB231_RS32225	COG1475	DNA binding
EB231_RS32270	COG3047	cAMP biosynthetic process
EB231_RS32280	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EB231_RS32295	COG4957	zinc ion binding
EB231_RS32300	COG1278	Cold shock
EB231_RS32305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB231_RS32310	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EB231_RS32315	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EB231_RS32350	COG0316	Belongs to the HesB IscA family
EB231_RS32360	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EB231_RS32365	COG1476	TRANSCRIPTIONal
EB231_RS32390	COG2207	Transcriptional regulator
EB231_RS32390	COG3708	Transcriptional regulator
EB231_RS32395	COG4948	Mandelate Racemase Muconate Lactonizing
EB231_RS32400	COG5598	trimethylamine methyltransferase
EB231_RS32410	COG2113	Glycine betaine
EB231_RS32425	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS32430	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS32435	COG0583	DNA-binding transcription factor activity
EB231_RS32445	COG1012	belongs to the aldehyde dehydrogenase family
EB231_RS32450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EB231_RS32480	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS32485	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS32490	COG2801	Transposase and inactivated derivatives
EB231_RS32500	COG1181	Belongs to the D-alanine--D-alanine ligase family
EB231_RS32505	COG4608	Belongs to the ABC transporter superfamily
EB231_RS32510	COG0444	Belongs to the ABC transporter superfamily
EB231_RS32540	COG3547	Transposase (IS116 IS110 IS902 family)
EB231_RS32555	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EB231_RS32560	COG1522	sequence-specific DNA binding
EB231_RS32565	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EB231_RS32565	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EB231_RS32575	COG0583	DNA-binding transcription factor activity
EB231_RS32580	COG2301	Belongs to the HpcH HpaI aldolase family
EB231_RS32590	COG3799	methylaspartate ammonia-lyase activity
EB231_RS32610	COG3415	Transposase
EB231_RS32660	COG0006	proline dipeptidase activity
EB231_RS32665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB231_RS32670	COG1126	abc transporter atp-binding protein
EB231_RS32680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB231_RS32685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EB231_RS32690	COG1024	Enoyl-CoA hydratase
EB231_RS32695	COG0045	succinate-CoA ligase (ADP-forming) activity
EB231_RS32695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EB231_RS32695	COG1042	CoA-binding domain protein
EB231_RS32700	COG1024	Enoyl-CoA hydratase
EB231_RS32705	COG3246	L-lysine catabolic process to acetate
EB231_RS32715	COG3328	transposase activity
EB231_RS32780	COG0006	proline dipeptidase activity
EB231_RS32795	COG1181	Belongs to the D-alanine--D-alanine ligase family
EB231_RS32800	COG2771	luxR family
EB231_RS32825	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EB231_RS32830	COG0316	Belongs to the HesB IscA family
EB231_RS32840	COG0602	queuosine metabolic process
EB231_RS32845	COG0720	synthase
EB231_RS32850	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EB231_RS32880	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EB231_RS32905	COG3383	formate dehydrogenase (NAD+) activity
EB231_RS32920	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EB231_RS32920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EB231_RS32945	COG4689	acetoacetate decarboxylase
EB231_RS32960	COG0745	RESPONSE REGULATOR receiver
EB231_RS32970	COG1433	Dinitrogenase iron-molybdenum cofactor
EB231_RS32975	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EB231_RS32980	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EB231_RS32985	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EB231_RS32990	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EB231_RS32995	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
EB231_RS33030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB231_RS33040	COG4608	Belongs to the ABC transporter superfamily
EB231_RS33045	COG0444	Belongs to the ABC transporter superfamily
EB231_RS33055	COG1349	DNA-binding transcription factor activity
EB231_RS33060	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EB231_RS33070	COG0367	asparagine synthase
EB231_RS33085	COG1213	nucleotidyl transferase
EB231_RS33100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB231_RS33105	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS33110	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EB231_RS33120	COG2124	cytochrome p450
EB231_RS33130	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EB231_RS33140	COG3383	formate dehydrogenase (NAD+) activity
EB231_RS33145	COG5420	small protein containing a coiled-coil domain
EB231_RS33150	COG5265	(ABC) transporter
EB231_RS33160	COG1104	cysteine desulfurase activity
EB231_RS33170	COG2086	electron transfer activity
EB231_RS33175	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EB231_RS33180	COG0644	oxidoreductase
EB231_RS33195	COG0535	radical SAM domain protein
EB231_RS33200	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EB231_RS33205	COG5554	nitrogen fixation
EB231_RS33210	COG5554	nitrogen fixation
EB231_RS33225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EB231_RS33230	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EB231_RS33260	COG2204	response regulator
EB231_RS33265	COG4191	Histidine kinase
EB231_RS33270	COG1301	dicarboxylic acid transport
EB231_RS33280	COG3604	Transcriptional regulator
EB231_RS33290	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EB231_RS33300	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EB231_RS33305	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EB231_RS33315	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EB231_RS33325	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EB231_RS33330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EB231_RS33335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EB231_RS33340	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EB231_RS33350	COG0459	protein refolding
EB231_RS33360	COG1012	belongs to the aldehyde dehydrogenase family
EB231_RS33390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EB231_RS33400	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EB231_RS33405	COG0720	synthase
EB231_RS33410	COG0602	queuosine metabolic process
EB231_RS33415	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EB231_RS33430	COG2022	thiamine diphosphate biosynthetic process
EB231_RS33445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB231_RS33450	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EB231_RS33505	COG0582	viral genome integration into host DNA
EB231_RS33515	COG0583	DNA-binding transcription factor activity
EB231_RS33525	COG0583	DNA-binding transcription factor activity
EB231_RS33530	COG0667	Aldo Keto reductase
EB231_RS33555	COG1294	oxidase, subunit
EB231_RS33560	COG1271	oxidase subunit
EB231_RS33565	COG0028	Belongs to the TPP enzyme family
EB231_RS33580	COG0025	NhaP-type Na H and K H
EB231_RS33610	COG0045	succinate-CoA ligase (ADP-forming) activity
EB231_RS33610	COG1042	CoA-binding domain protein
EB231_RS33610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EB231_RS33620	COG2217	Heavy metal translocating P-type atpase
EB231_RS33670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EB231_RS33680	COG3794	PFAM blue (type 1) copper domain protein
EB231_RS33705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EB231_RS33730	COG2010	Cytochrome c
EB231_RS33755	COG0517	IMP dehydrogenase activity
EB231_RS33790	COG2205	protein histidine kinase activity
EB231_RS33795	COG0745	RESPONSE REGULATOR receiver
EB231_RS33825	COG4191	Histidine kinase
EB231_RS33830	COG4566	intracellular signal transduction
EB231_RS33835	COG0156	8-amino-7-oxononanoate synthase activity
EB231_RS33880	COG1129	ABC transporter
EB231_RS33890	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS33895	COG1879	ABC-type sugar transport system periplasmic component
EB231_RS33900	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS33910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB231_RS33935	COG4952	isomerase
EB231_RS33940	COG1028	Short-chain dehydrogenase reductase Sdr
EB231_RS33940	COG3347	Dehydrogenase
EB231_RS33945	COG1349	DNA-binding transcription factor activity
EB231_RS33955	COG1129	ABC transporter
EB231_RS33960	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS33965	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB231_RS33970	COG3254	rhamnose metabolic process
EB231_RS33975	COG1070	Carbohydrate kinase
EB231_RS33980	COG3457	Alanine racemase
EB231_RS33985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB231_RS33995	COG0156	8-amino-7-oxononanoate synthase activity
EB231_RS34000	COG0436	Aminotransferase
EB231_RS34005	COG1970	mechanosensitive ion channel activity
EB231_RS34035	COG0167	dihydroorotate dehydrogenase activity
EB231_RS34040	COG0534	Mate efflux family protein
EB231_RS34045	COG0123	including yeast histone deacetylase and acetoin utilization protein
EB231_RS34090	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EB231_RS34130	COG2197	response regulator
EB231_RS34145	COG1129	ABC transporter
EB231_RS34150	COG4214	carbohydrate transport
EB231_RS34160	COG0717	Belongs to the dCTP deaminase family
EB231_RS34175	COG2967	ApaG domain
EB231_RS34185	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EB231_RS34190	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EB231_RS34200	COG0598	Magnesium transport protein CorA
EB231_RS34205	COG0704	Plays a role in the regulation of phosphate uptake
EB231_RS34210	COG5002	protein histidine kinase activity
EB231_RS34215	COG2326	polyphosphate kinase activity
EB231_RS34220	COG1024	Enoyl-CoA hydratase
EB231_RS34230	COG2197	response regulator
EB231_RS34245	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EB231_RS34265	COG1250	3-hydroxyacyl-CoA dehydrogenase
EB231_RS34265	COG1024	Enoyl-CoA hydratase
EB231_RS34270	COG0183	Belongs to the thiolase family
EB231_RS34275	COG1960	acyl-CoA dehydrogenase activity
EB231_RS34280	COG1960	acyl-CoA dehydrogenase activity
EB231_RS34285	COG0789	Transcriptional regulator
EB231_RS34410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EB231_RS34435	COG3772	lysozyme
EB231_RS34550	COG0616	signal peptide processing
EB231_RS34645	COG1061	Type III restriction enzyme res subunit
EB231_RS34790	COG0730	response to heat
EB231_RS34800	COG0443	Heat shock 70 kDa protein
EB231_RS34810	COG0243	molybdopterin cofactor binding
EB231_RS34815	COG0437	4 iron, 4 sulfur cluster binding
EB231_RS34820	COG3302	dmso reductase anchor subunit
EB231_RS34830	COG1201	RNA secondary structure unwinding
EB231_RS34835	COG0791	NLP P60 protein
EB231_RS34845	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EB231_RS34880	COG4964	Belongs to the GSP D family
EB231_RS34920	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EB231_RS34925	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EB231_RS34930	COG1024	Enoyl-CoA hydratase
EB231_RS34935	COG0268	Binds directly to 16S ribosomal RNA