locus-tag	class	description
THEBA_RS00120	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
THEBA_RS00140	COG3234	Protein of unknown function (DUF1175)
THEBA_RS00145	COG2373	Large extracellular alpha-helical protein
THEBA_RS00160	COG0534	Mate efflux family protein
THEBA_RS00165	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
THEBA_RS00170	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
THEBA_RS00175	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
THEBA_RS00180	COG0126	phosphoglycerate kinase activity
THEBA_RS00180	COG0149	triose-phosphate isomerase activity
THEBA_RS00195	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
THEBA_RS00200	COG0391	Required for morphogenesis under gluconeogenic growth conditions
THEBA_RS00210	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
THEBA_RS00215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
THEBA_RS00220	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
THEBA_RS00240	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
THEBA_RS00250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
THEBA_RS00255	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
THEBA_RS00265	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
THEBA_RS00270	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
THEBA_RS00300	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
THEBA_RS00305	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
THEBA_RS00310	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
THEBA_RS00315	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
THEBA_RS00345	COG0697	spore germination
THEBA_RS00350	COG0312	modulator of DNA gyrase
THEBA_RS00355	COG0312	modulator of DNA gyrase
THEBA_RS00365	COG0174	glutamine synthetase
THEBA_RS00370	COG0138	bifunctional purine biosynthesis protein purh
THEBA_RS00410	COG1181	Belongs to the D-alanine--D-alanine ligase family
THEBA_RS00465	COG5012	cobalamin binding
THEBA_RS00470	COG1322	Protein conserved in bacteria
THEBA_RS00475	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
THEBA_RS00485	COG2832	Protein of unknown function (DUF454)
THEBA_RS00490	COG0753	catalase activity
THEBA_RS00495	COG0543	2 iron, 2 sulfur cluster binding
THEBA_RS00500	COG0493	'glutamate synthase
THEBA_RS00500	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
THEBA_RS00515	COG1175	transmembrane transport
THEBA_RS00520	COG0395	ABC-type sugar transport system, permease component
THEBA_RS00530	COG2205	protein histidine kinase activity
THEBA_RS00530	COG2770	Histidine kinase
THEBA_RS00535	COG0745	RESPONSE REGULATOR receiver
THEBA_RS00555	COG3850	Histidine kinase
THEBA_RS00555	COG5002	protein histidine kinase activity
THEBA_RS00560	COG0745	RESPONSE REGULATOR receiver
THEBA_RS00575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
THEBA_RS00580	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
THEBA_RS00585	COG1506	peptidase
THEBA_RS00585	COG4946	Tricorn protease homolog
THEBA_RS00585	COG0823	Involved in the tonB-independent uptake of proteins
THEBA_RS00615	COG0392	lysyltransferase activity
THEBA_RS00625	COG0438	transferase activity, transferring glycosyl groups
THEBA_RS00820	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
THEBA_RS00840	COG0395	ABC-type sugar transport system, permease component
THEBA_RS00855	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
THEBA_RS00860	COG0191	fructose-bisphosphate aldolase activity
THEBA_RS00870	COG1979	alcohol dehydrogenase
THEBA_RS00875	COG0494	nUDIX hydrolase
THEBA_RS00895	COG0527	aspartate kinase activity
THEBA_RS00900	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
THEBA_RS00905	COG0083	homoserine kinase activity
THEBA_RS00910	COG0367	asparagine synthase
THEBA_RS00940	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
THEBA_RS00945	COG0083	homoserine kinase activity
THEBA_RS00950	COG0367	asparagine synthase
THEBA_RS00965	COG1943	Transposase
THEBA_RS00995	COG2337	Toxic component of a toxin-antitoxin (TA) module
THEBA_RS01015	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
THEBA_RS01025	COG1131	(ABC) transporter
THEBA_RS01030	COG1131	(ABC) transporter
THEBA_RS01035	COG1725	Transcriptional regulator
THEBA_RS01040	COG1073	alpha beta
THEBA_RS01050	COG1131	(ABC) transporter
THEBA_RS01065	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
THEBA_RS01110	COG0612	Peptidase, M16
THEBA_RS01115	COG1185	polyribonucleotide nucleotidyltransferase activity
THEBA_RS01120	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
THEBA_RS01125	COG1760	l-serine dehydratase
THEBA_RS01130	COG1760	l-serine dehydratase
THEBA_RS01135	COG0148	phosphopyruvate hydratase activity
THEBA_RS01140	COG0528	UMP kinase activity
THEBA_RS01145	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
THEBA_RS01150	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
THEBA_RS01155	COG1959	2 iron, 2 sulfur cluster binding
THEBA_RS01160	COG0552	protein localization to endoplasmic reticulum
THEBA_RS01165	COG0442	prolyl-tRNA aminoacylation
THEBA_RS01170	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
THEBA_RS01185	COG0601	transmembrane transport
THEBA_RS01190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THEBA_RS01195	COG0444	Belongs to the ABC transporter superfamily
THEBA_RS01200	COG4608	Belongs to the ABC transporter superfamily
THEBA_RS01205	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
THEBA_RS01210	COG1323	Belongs to the UPF0348 family
THEBA_RS01230	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THEBA_RS01305	COG0052	Belongs to the universal ribosomal protein uS2 family
THEBA_RS01310	COG0799	negative regulation of ribosome biogenesis
THEBA_RS01315	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
THEBA_RS01320	COG0416	fatty acid biosynthetic process
THEBA_RS01325	COG0333	Belongs to the bacterial ribosomal protein bL32 family
THEBA_RS01340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
THEBA_RS01350	COG0776	regulation of translation
THEBA_RS01360	COG3584	3D domain protein
THEBA_RS01370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
THEBA_RS01375	COG1045	serine acetyltransferase
THEBA_RS01395	COG0628	permease
THEBA_RS01415	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
THEBA_RS01425	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
THEBA_RS01435	COG1842	Phage shock protein A
THEBA_RS01450	COG0280	phosphate acetyltransferase
THEBA_RS01460	COG2815	serine threonine protein kinase
THEBA_RS01460	COG0515	serine threonine protein kinase
THEBA_RS01465	COG0142	geranyltranstransferase activity
THEBA_RS01480	COG0301	tRNA thio-modification
THEBA_RS01495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
THEBA_RS01505	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
THEBA_RS01510	COG0291	Belongs to the bacterial ribosomal protein bL35 family
THEBA_RS01515	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
THEBA_RS01525	COG0489	protein tyrosine kinase activity
THEBA_RS01530	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
THEBA_RS01535	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
THEBA_RS01540	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
THEBA_RS01550	COG1435	thymidine kinase activity
THEBA_RS01555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
THEBA_RS01560	COG0228	four-way junction DNA binding
THEBA_RS01565	COG1837	Belongs to the UPF0109 family
THEBA_RS01570	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
THEBA_RS01575	COG0336	Belongs to the RNA methyltransferase TrmD family
THEBA_RS01580	COG4752	Belongs to the RNA methyltransferase TrmD family
THEBA_RS01585	COG0335	large ribosomal subunit rRNA binding
THEBA_RS01590	COG0681	Belongs to the peptidase S26 family
THEBA_RS01600	COG1469	GTP cyclohydrolase I activity
THEBA_RS01605	COG0357	Ribosomal RNA small subunit methyltransferase G
THEBA_RS01610	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
THEBA_RS01615	COG1994	Peptidase M50
THEBA_RS01620	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
THEBA_RS01630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
THEBA_RS01635	COG0564	pseudouridine synthase activity
THEBA_RS01660	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
THEBA_RS01660	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
THEBA_RS01690	COG0719	Fe-S assembly protein
THEBA_RS01695	COG0719	Fe-S assembly protein
THEBA_RS01700	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
THEBA_RS01725	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
THEBA_RS01730	COG3206	protein involved in exopolysaccharide biosynthesis
THEBA_RS01755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THEBA_RS01760	COG0601	transmembrane transport
THEBA_RS01770	COG4608	Belongs to the ABC transporter superfamily
THEBA_RS01775	COG0444	Belongs to the ABC transporter superfamily
THEBA_RS01780	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
THEBA_RS01785	COG0305	Participates in initiation and elongation during chromosome replication
THEBA_RS01790	COG1131	(ABC) transporter
THEBA_RS01805	COG1363	Peptidase, m42
THEBA_RS01810	COG0719	Fe-S assembly protein
THEBA_RS01815	COG0396	ATPase activity
THEBA_RS01825	COG0432	Pfam Uncharacterised protein family UPF0047
THEBA_RS01835	COG2894	cell division
THEBA_RS01840	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
THEBA_RS01845	COG1454	alcohol dehydrogenase
THEBA_RS01855	COG2333	competence protein COMEC
THEBA_RS01855	COG0658	competence protein
THEBA_RS01860	COG0735	belongs to the Fur family
THEBA_RS01865	COG0195	Participates in both transcription termination and antitermination
THEBA_RS01870	COG0779	Required for maturation of 30S ribosomal subunits
THEBA_RS01885	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
THEBA_RS01890	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
THEBA_RS01890	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
THEBA_RS01895	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
THEBA_RS01900	COG0772	Belongs to the SEDS family
THEBA_RS01910	COG1228	amidohydrolase
THEBA_RS01915	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
THEBA_RS01920	COG4536	flavin adenine dinucleotide binding
THEBA_RS01930	COG0494	nUDIX hydrolase
THEBA_RS01935	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
THEBA_RS01940	COG1079	Belongs to the binding-protein-dependent transport system permease family
THEBA_RS01945	COG4603	Belongs to the binding-protein-dependent transport system permease family
THEBA_RS01950	COG3845	ABC transporter
THEBA_RS01955	COG1744	ABC transporter substrate-binding protein PnrA-like
THEBA_RS01970	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
THEBA_RS01985	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THEBA_RS01990	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
THEBA_RS02000	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
THEBA_RS02005	COG2137	regulation of response to DNA damage stimulus
THEBA_RS02010	COG1418	mRNA catabolic process
THEBA_RS02020	COG0037	tRNA processing
THEBA_RS02025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
THEBA_RS02040	COG0745	RESPONSE REGULATOR receiver
THEBA_RS02045	COG5002	protein histidine kinase activity
THEBA_RS02060	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
THEBA_RS02075	COG1713	HD superfamily hydrolase involved in NAD metabolism
THEBA_RS02075	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
THEBA_RS02090	COG1956	GAF domain-containing protein
THEBA_RS02110	COG1293	RNA-binding protein homologous to eukaryotic snRNP
THEBA_RS02120	COG4112	unkown
THEBA_RS02130	COG0617	tRNA 3'-terminal CCA addition
THEBA_RS02130	COG3620	sequence-specific DNA binding
THEBA_RS02130	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
THEBA_RS02135	COG2204	response regulator
THEBA_RS02165	COG0395	ABC-type sugar transport system, permease component
THEBA_RS02170	COG1175	transmembrane transport
THEBA_RS02180	COG1486	melibiose metabolic process
THEBA_RS02185	COG0519	Catalyzes the synthesis of GMP from XMP
THEBA_RS02205	COG1428	Deoxynucleoside kinase
THEBA_RS02210	COG1428	Deoxynucleoside kinase
THEBA_RS02220	COG1523	belongs to the glycosyl hydrolase 13 family
THEBA_RS02235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
THEBA_RS02240	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
THEBA_RS02250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
THEBA_RS02255	COG1181	Belongs to the D-alanine--D-alanine ligase family
THEBA_RS02260	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
THEBA_RS02265	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
THEBA_RS02270	COG0758	DNA mediated transformation
THEBA_RS02275	COG0191	fructose-bisphosphate aldolase activity
THEBA_RS02280	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
THEBA_RS02305	COG1307	EDD domain protein, DegV family
THEBA_RS02310	COG1609	Transcriptional regulator
THEBA_RS02325	COG1653	transport
THEBA_RS02330	COG0438	transferase activity, transferring glycosyl groups
THEBA_RS02355	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
THEBA_RS02370	COG0747	negative chemotaxis
THEBA_RS02380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THEBA_RS02410	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
THEBA_RS02415	COG1242	4 iron, 4 sulfur cluster binding
THEBA_RS02420	COG1196	nuclear chromosome segregation
THEBA_RS02425	COG0697	spore germination
THEBA_RS02445	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
THEBA_RS02465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
THEBA_RS02470	COG0166	Belongs to the GPI family
THEBA_RS02480	COG0237	dephospho-CoA kinase activity
THEBA_RS02485	COG1653	transport
THEBA_RS02500	COG1125	glycine betaine transport
THEBA_RS02500	COG0517	IMP dehydrogenase activity
THEBA_RS02515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
THEBA_RS02515	COG0574	Belongs to the PEP-utilizing enzyme family
THEBA_RS02520	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
THEBA_RS02530	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
THEBA_RS02530	COG0674	pyruvate-flavodoxin oxidoreductase activity
THEBA_RS02535	COG2359	stage V sporulation protein S
THEBA_RS02560	COG0534	Mate efflux family protein
THEBA_RS02565	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
THEBA_RS02585	COG3608	succinylglutamate desuccinylase aspartoacylase
THEBA_RS02610	COG1201	RNA secondary structure unwinding
THEBA_RS02635	COG0395	ABC-type sugar transport system, permease component
THEBA_RS02640	COG4209	transmembrane transport
THEBA_RS02645	COG1653	transport
THEBA_RS02675	COG0477	Major facilitator Superfamily
THEBA_RS02680	COG1827	regulation of RNA biosynthetic process
THEBA_RS02700	COG0850	regulation of cytokinetic process
THEBA_RS02720	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
THEBA_RS02735	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
THEBA_RS02740	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
THEBA_RS02755	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
THEBA_RS02760	COG1482	cell wall glycoprotein biosynthetic process
THEBA_RS02770	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
THEBA_RS02810	COG0698	ribose 5-phosphate isomerase
THEBA_RS02815	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
THEBA_RS02820	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
THEBA_RS02825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
THEBA_RS02825	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
THEBA_RS02835	COG0489	protein tyrosine kinase activity
THEBA_RS02845	COG1596	polysaccharide export
THEBA_RS02855	COG3852	Histidine kinase
THEBA_RS02865	COG2264	protein methyltransferase activity
THEBA_RS02870	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
THEBA_RS02875	COG1307	EDD domain protein, DegV family
THEBA_RS02890	COG0220	tRNA (guanine-N7-)-methyltransferase activity
THEBA_RS02895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
THEBA_RS02900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
THEBA_RS02905	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
THEBA_RS02915	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
THEBA_RS02920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
THEBA_RS02930	COG1032	radical SAM domain protein
THEBA_RS02935	COG1242	4 iron, 4 sulfur cluster binding
THEBA_RS02945	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
THEBA_RS02955	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
THEBA_RS02985	COG0343	queuine tRNA-ribosyltransferase activity
THEBA_RS02990	COG3404	Formiminotransferase-cyclodeaminase
THEBA_RS02995	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
THEBA_RS03005	COG2003	Belongs to the UPF0758 family
THEBA_RS03035	COG2078	PFAM AMMECR1 domain protein
THEBA_RS03045	COG0557	exoribonuclease II activity
THEBA_RS03055	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
THEBA_RS03115	COG0598	Magnesium transport protein CorA
THEBA_RS03120	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
THEBA_RS03120	COG2199	diguanylate cyclase activity
THEBA_RS03125	COG0561	phosphatase activity
THEBA_RS03130	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
THEBA_RS03135	COG0425	Belongs to the sulfur carrier protein TusA family
THEBA_RS03140	COG2391	methyltransferase activity
THEBA_RS03160	COG0425	Belongs to the sulfur carrier protein TusA family
THEBA_RS03185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
THEBA_RS03210	COG3681	Belongs to the UPF0597 family
THEBA_RS03255	COG1136	(ABC) transporter
THEBA_RS03255	COG0577	efflux transmembrane transporter activity
THEBA_RS03290	COG2738	Putative neutral zinc metallopeptidase
THEBA_RS03300	COG0820	rRNA (adenine-C2-)-methyltransferase activity
THEBA_RS03305	COG1162	GTPase activity
THEBA_RS03310	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
THEBA_RS03315	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
THEBA_RS03320	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
THEBA_RS03325	COG0544	peptidyl-prolyl cis-trans isomerase activity
THEBA_RS03340	COG0217	transcriptional regulatory protein
THEBA_RS03345	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
THEBA_RS03350	COG0564	pseudouridine synthase activity
THEBA_RS03355	COG0587	DNA-directed DNA polymerase activity
THEBA_RS03365	COG2045	Belongs to the ComB family
THEBA_RS03380	COG0436	Aminotransferase
THEBA_RS03395	COG1968	undecaprenyl-diphosphatase activity
THEBA_RS03405	COG0297	glycogen (starch) synthase activity
THEBA_RS03415	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
THEBA_RS03420	COG0792	nuclease activity
THEBA_RS03425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
THEBA_RS03435	COG0101	tRNA pseudouridine synthase activity
THEBA_RS03445	COG0653	protein targeting
THEBA_RS03450	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
THEBA_RS03455	COG0275	rRNA processing
THEBA_RS03465	COG0768	penicillin binding
THEBA_RS03475	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
THEBA_RS03480	COG0049	tRNA binding
THEBA_RS03485	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
THEBA_RS03490	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
THEBA_RS03495	COG0051	transcription antitermination factor activity, RNA binding
THEBA_RS03500	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
THEBA_RS03505	COG0088	Forms part of the polypeptide exit tunnel
THEBA_RS03510	COG0089	rRNA binding
THEBA_RS03515	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
THEBA_RS03520	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
THEBA_RS03530	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
THEBA_RS03535	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
THEBA_RS03540	COG0255	Belongs to the universal ribosomal protein uL29 family
THEBA_RS03545	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
THEBA_RS03550	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
THEBA_RS03555	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
THEBA_RS03560	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
THEBA_RS03565	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
THEBA_RS03570	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
THEBA_RS03575	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
THEBA_RS03580	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
THEBA_RS03585	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
THEBA_RS03590	COG1841	ribosomal large subunit assembly
THEBA_RS03595	COG0200	Binds to the 23S rRNA
THEBA_RS03600	COG0201	protein transport
THEBA_RS03605	COG0563	adenylate kinase activity
THEBA_RS03615	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
THEBA_RS03620	COG0257	Belongs to the bacterial ribosomal protein bL36 family
THEBA_RS03625	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
THEBA_RS03630	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
THEBA_RS03635	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
THEBA_RS03640	COG0202	RNA polymerase activity
THEBA_RS03645	COG0203	ribosomal protein L17
THEBA_RS03650	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
THEBA_RS03655	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
THEBA_RS03665	COG1515	deoxyribonuclease V activity
THEBA_RS03675	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
THEBA_RS03680	COG1459	type II secretion system
THEBA_RS03715	COG1355	regulation of microtubule-based process
THEBA_RS03730	COG1193	negative regulation of DNA recombination
THEBA_RS03735	COG0736	holo-[acyl-carrier-protein] synthase activity
THEBA_RS03740	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
THEBA_RS03745	COG1104	cysteine desulfurase activity
THEBA_RS03750	COG1561	YicC-like family, N-terminal region
THEBA_RS03755	COG2052	Domain of unknown function (DUF370)
THEBA_RS03760	COG0194	GDP metabolic process
THEBA_RS03765	COG1758	RNA polymerase activity
THEBA_RS03780	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
THEBA_RS03785	COG0250	Participates in transcription elongation, termination and antitermination
THEBA_RS03790	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
THEBA_RS03795	COG0081	regulation of translation
THEBA_RS03800	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
THEBA_RS03805	COG0222	ribosome binding
THEBA_RS03810	COG0085	RNA polymerase activity
THEBA_RS03815	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
THEBA_RS03820	COG3845	ABC transporter
THEBA_RS03825	COG4603	Belongs to the binding-protein-dependent transport system permease family
THEBA_RS03830	COG1079	Belongs to the binding-protein-dependent transport system permease family
THEBA_RS03835	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
THEBA_RS03855	COG0489	protein tyrosine kinase activity
THEBA_RS03870	COG2264	protein methyltransferase activity
THEBA_RS03875	COG1175	transmembrane transport
THEBA_RS03880	COG0395	ABC-type sugar transport system, permease component
THEBA_RS03885	COG1653	transport
THEBA_RS03900	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
THEBA_RS03900	COG1328	CTP reductase activity
THEBA_RS03905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
THEBA_RS03915	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
THEBA_RS03930	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
THEBA_RS03935	COG0218	Necessary for normal cell division and for the maintenance of normal septation
THEBA_RS03940	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
THEBA_RS03945	COG2723	6-phospho-beta-galactosidase activity
THEBA_RS03950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
THEBA_RS03960	COG4974	Belongs to the 'phage' integrase family
THEBA_RS03965	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
THEBA_RS03975	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
THEBA_RS03980	COG0728	peptidoglycan biosynthetic process
THEBA_RS03985	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
THEBA_RS03995	COG2176	DNA-directed DNA polymerase activity
THEBA_RS04000	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
THEBA_RS04015	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
THEBA_RS04020	COG4869	propanediol catabolic process
THEBA_RS04040	COG1098	S1 RNA binding domain
THEBA_RS04045	COG0254	rRNA binding
THEBA_RS04055	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
THEBA_RS04060	COG0628	permease
THEBA_RS04075	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
THEBA_RS04080	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
THEBA_RS04100	COG0706	membrane insertase activity
THEBA_RS04105	COG0594	ribonuclease P activity
THEBA_RS04110	COG0230	Belongs to the bacterial ribosomal protein bL34 family
THEBA_RS04115	COG0497	DNA recombination
THEBA_RS04130	COG0330	HflC and HflK could
THEBA_RS04135	COG0330	HflC and HflK could
THEBA_RS04140	COG1739	Uncharacterized protein family UPF0029
THEBA_RS04145	COG0768	penicillin binding
THEBA_RS04160	COG1077	Cell shape determining protein MreB Mrl
THEBA_RS04165	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
THEBA_RS04170	COG0481	GTPase activity
THEBA_RS04175	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
THEBA_RS04180	COG0504	CTP synthase activity
THEBA_RS04185	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
THEBA_RS04195	COG0395	ABC-type sugar transport system, permease component
THEBA_RS04210	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
THEBA_RS04215	COG1923	regulation of RNA biosynthetic process
THEBA_RS04220	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
THEBA_RS04235	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
THEBA_RS04240	COG0268	Binds directly to 16S ribosomal RNA
THEBA_RS04245	COG3842	ATPase activity
THEBA_RS04255	COG1805	sodium ion transport
THEBA_RS04265	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
THEBA_RS04270	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
THEBA_RS04295	COG0739	heme binding
THEBA_RS04310	COG1013	pyruvate-flavodoxin oxidoreductase activity
THEBA_RS04325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
THEBA_RS04340	COG0154	amidase activity
THEBA_RS04360	COG4251	negative regulation of phosphorylation
THEBA_RS04375	COG2267	carboxylic ester hydrolase activity
THEBA_RS04380	COG0196	riboflavin kinase activity
THEBA_RS04385	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
THEBA_RS04390	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
THEBA_RS04400	COG3328	transposase activity
THEBA_RS04445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
THEBA_RS04455	COG0747	negative chemotaxis
THEBA_RS04465	COG2271	Major facilitator Superfamily
THEBA_RS04470	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
THEBA_RS04475	COG0751	glycine-tRNA ligase activity
THEBA_RS04485	COG1461	Dihydroxyacetone kinase
THEBA_RS04495	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
THEBA_RS04500	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
THEBA_RS04505	COG2759	Belongs to the formate--tetrahydrofolate ligase family
THEBA_RS04510	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
THEBA_RS04520	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
THEBA_RS04525	COG0006	proline dipeptidase activity
THEBA_RS04530	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
THEBA_RS04535	COG0740	serine-type endopeptidase activity
THEBA_RS04540	COG2052	Domain of unknown function (DUF370)
THEBA_RS04555	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
THEBA_RS04580	COG0683	leucine binding
THEBA_RS04585	COG1063	alcohol dehydrogenase
THEBA_RS04590	COG0156	8-amino-7-oxononanoate synthase activity
THEBA_RS04605	COG0512	Glutamine amidotransferase of anthranilate synthase
THEBA_RS04605	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
THEBA_RS04615	COG2986	histidine ammonia-lyase
THEBA_RS04620	COG0765	amino acid transport
THEBA_RS04625	COG1126	abc transporter atp-binding protein
THEBA_RS04630	COG0765	amino acid transport
THEBA_RS04635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
THEBA_RS04640	COG0482	sulfurtransferase activity
THEBA_RS04675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
THEBA_RS04690	COG2076	Multidrug Resistance protein
THEBA_RS04715	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
THEBA_RS04720	COG0395	ABC-type sugar transport system, permease component
THEBA_RS04730	COG2080	2 iron, 2 sulfur cluster binding
THEBA_RS04730	COG1529	Aldehyde oxidase and xanthine dehydrogenase
THEBA_RS04750	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
THEBA_RS04765	COG0167	dihydroorotate dehydrogenase activity
THEBA_RS04780	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
THEBA_RS04785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
THEBA_RS04790	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
THEBA_RS04795	COG0584	glycerophosphoryl diester phosphodiesterase
THEBA_RS04810	COG1175	transmembrane transport
THEBA_RS04815	COG0395	ABC-type sugar transport system, permease component
THEBA_RS04830	COG0360	Binds together with S18 to 16S ribosomal RNA
THEBA_RS04835	COG0629	single-stranded DNA binding
THEBA_RS04840	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
THEBA_RS04845	COG0359	binds to the 23S rRNA
THEBA_RS04850	COG1234	tRNA 3'-trailer cleavage
THEBA_RS04875	COG0492	ferredoxin-NADP+ reductase activity
THEBA_RS04880	COG1619	proteins homologs of microcin C7 resistance protein MccF
THEBA_RS04895	COG1126	abc transporter atp-binding protein
THEBA_RS04900	COG0765	amino acid transport
THEBA_RS04905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
THEBA_RS04910	COG1428	Deoxynucleoside kinase
THEBA_RS04935	COG2379	hydroxypyruvate reductase
THEBA_RS04940	COG0395	ABC-type sugar transport system, permease component
THEBA_RS04945	COG1175	transmembrane transport
THEBA_RS04975	COG0667	Aldo Keto reductase
THEBA_RS04980	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
THEBA_RS04985	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
THEBA_RS04990	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
THEBA_RS04995	COG0193	aminoacyl-tRNA hydrolase activity
THEBA_RS05000	COG0556	nucleotide-excision repair
THEBA_RS05005	COG0632	four-way junction helicase activity
THEBA_RS05010	COG0285	dihydrofolate synthase activity
THEBA_RS05015	COG0525	valine-tRNA ligase activity
THEBA_RS05020	COG3695	enzyme binding
THEBA_RS05035	COG2081	HI0933 family
THEBA_RS05045	COG2096	Adenosyltransferase
THEBA_RS05065	COG1307	EDD domain protein, DegV family
THEBA_RS05085	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
THEBA_RS05100	COG0297	glycogen (starch) synthase activity
THEBA_RS05105	COG1032	radical SAM domain protein
THEBA_RS05135	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
THEBA_RS05155	COG4120	Belongs to the binding-protein-dependent transport system permease family
THEBA_RS05165	COG1079	Belongs to the binding-protein-dependent transport system permease family
THEBA_RS05170	COG4603	Belongs to the binding-protein-dependent transport system permease family
THEBA_RS05175	COG3845	ABC transporter
THEBA_RS05185	COG1528	Iron-storage protein
THEBA_RS05190	COG0737	Belongs to the 5'-nucleotidase family
THEBA_RS05200	COG4213	ABC transporter substrate-binding protein
THEBA_RS05205	COG1129	ABC transporter
THEBA_RS05210	COG1172	Belongs to the binding-protein-dependent transport system permease family
THEBA_RS05240	COG0785	Cytochrome C biogenesis protein
THEBA_RS05250	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
THEBA_RS05250	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
THEBA_RS05255	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
THEBA_RS05255	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
THEBA_RS05260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
THEBA_RS05265	COG1573	uracil-dna glycosylase
THEBA_RS05270	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
THEBA_RS05280	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
THEBA_RS05285	COG2255	four-way junction helicase activity
THEBA_RS05290	COG0017	Asparaginyl-tRNA synthetase
THEBA_RS05300	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
THEBA_RS05305	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
THEBA_RS05310	COG0539	negative regulation of cytoplasmic translation
THEBA_RS05315	COG1160	GTP binding
THEBA_RS05320	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
THEBA_RS05340	COG0355	proton-transporting ATP synthase activity, rotational mechanism
THEBA_RS05345	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
THEBA_RS05350	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
THEBA_RS05355	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
THEBA_RS05360	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
THEBA_RS05365	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
THEBA_RS05370	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
THEBA_RS05375	COG0356	it plays a direct role in the translocation of protons across the membrane
THEBA_RS05385	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
THEBA_RS05385	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
THEBA_RS05395	COG0084	hydrolase, TatD family'
THEBA_RS05400	COG0012	GTP binding
THEBA_RS05405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
THEBA_RS05425	COG0395	ABC-type sugar transport system, permease component
THEBA_RS05445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
THEBA_RS05450	COG0537	adenosine 5'-monophosphoramidase activity
THEBA_RS05455	COG2813	Specifically methylates the guanine in position
THEBA_RS05460	COG1116	anion transmembrane transporter activity
THEBA_RS05465	COG1122	ATPase activity
THEBA_RS05470	COG1811	Na channel or pump
THEBA_RS05475	COG1013	pyruvate-flavodoxin oxidoreductase activity
THEBA_RS05485	COG1773	rubredoxin
THEBA_RS05490	COG2033	superoxide reductase activity
THEBA_RS05520	COG4608	Belongs to the ABC transporter superfamily
THEBA_RS05525	COG0444	Belongs to the ABC transporter superfamily
THEBA_RS05535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THEBA_RS05540	COG0601	transmembrane transport
THEBA_RS05545	COG0747	negative chemotaxis
THEBA_RS05565	COG1132	(ABC) transporter
THEBA_RS05570	COG1132	(ABC) transporter
THEBA_RS05575	COG1752	Esterase of the alpha-beta hydrolase superfamily
THEBA_RS05585	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
THEBA_RS05610	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
THEBA_RS05620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
THEBA_RS05630	COG2171	N-acyltransferase activity
THEBA_RS05635	COG0527	aspartate kinase activity
THEBA_RS05640	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
THEBA_RS05645	COG0019	diaminopimelate decarboxylase activity
THEBA_RS05650	COG1388	LysM domain
THEBA_RS05650	COG4942	peptidase
THEBA_RS05660	COG3328	transposase activity
THEBA_RS05665	COG1132	(ABC) transporter
THEBA_RS05710	COG1846	Transcriptional regulator
THEBA_RS05740	COG1045	serine acetyltransferase
THEBA_RS05775	COG3328	transposase activity
THEBA_RS05830	COG3422	double-strand break repair
THEBA_RS05835	COG2337	Toxic component of a toxin-antitoxin (TA) module
THEBA_RS05925	COG1404	Belongs to the peptidase S8 family
THEBA_RS05935	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
THEBA_RS05945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
THEBA_RS05960	COG0438	transferase activity, transferring glycosyl groups
THEBA_RS05980	COG1215	transferase activity, transferring glycosyl groups
THEBA_RS06050	COG2361	Protein of unknown function DUF86
THEBA_RS06105	COG1744	ABC transporter substrate-binding protein PnrA-like
THEBA_RS06115	COG1309	transcriptional regulator
THEBA_RS06125	COG1162	GTPase activity
THEBA_RS06135	COG3290	protein histidine kinase activity
THEBA_RS06135	COG3829	transcription factor binding
THEBA_RS06150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
THEBA_RS06155	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
THEBA_RS06190	COG1131	(ABC) transporter
THEBA_RS06220	COG2359	stage V sporulation protein S
THEBA_RS06235	COG0261	This protein binds to 23S rRNA in the presence of protein L20
THEBA_RS06240	COG0211	Belongs to the bacterial ribosomal protein bL27 family
THEBA_RS06245	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
THEBA_RS06250	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
THEBA_RS06255	COG0358	DNA primase activity
THEBA_RS06260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
THEBA_RS06265	COG3842	ATPase activity
THEBA_RS06275	COG0516	GMP reductase activity
THEBA_RS06280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THEBA_RS06285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
THEBA_RS06295	COG0187	DNA topoisomerase II activity
THEBA_RS06310	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
THEBA_RS06315	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
THEBA_RS06340	COG5012	cobalamin binding
THEBA_RS06345	COG1606	tRNA processing
THEBA_RS06350	COG0561	phosphatase activity
THEBA_RS06355	COG0815	Transfers the fatty acyl group on membrane lipoproteins
THEBA_RS06375	COG0483	inositol monophosphate 1-phosphatase activity
THEBA_RS06380	COG0072	phenylalanine-tRNA ligase activity
THEBA_RS06380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
THEBA_RS06385	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
THEBA_RS06405	COG1595	DNA-templated transcription, initiation
THEBA_RS06410	COG1362	aminopeptidase activity
THEBA_RS06415	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
THEBA_RS06420	COG1178	ABC-type Fe3 transport system permease component
THEBA_RS06430	COG1546	Belongs to the CinA family
THEBA_RS06430	COG1058	Belongs to the CinA family
THEBA_RS06435	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
THEBA_RS06450	COG0626	cystathionine gamma-synthase activity
THEBA_RS06460	COG0546	phosphoglycolate phosphatase activity
THEBA_RS06475	COG1704	LemA family
THEBA_RS06520	COG1028	Short-chain dehydrogenase reductase Sdr
THEBA_RS06535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
THEBA_RS06545	COG1131	(ABC) transporter
THEBA_RS06575	COG2205	protein histidine kinase activity
THEBA_RS06605	COG0306	phosphate transporter
THEBA_RS06645	COG1659	Linocin_M18 bacteriocin protein
THEBA_RS06650	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
THEBA_RS06680	COG1304	FMN binding
THEBA_RS06690	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
THEBA_RS06710	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
THEBA_RS06715	COG0776	regulation of translation
THEBA_RS06720	COG0322	excinuclease ABC activity
THEBA_RS06730	COG2264	protein methyltransferase activity
THEBA_RS06740	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
THEBA_RS06745	COG1774	PSP1 C-terminal conserved region
THEBA_RS06750	COG0470	DNA polymerase III
THEBA_RS06755	COG0105	UTP biosynthetic process
THEBA_RS06770	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
THEBA_RS06775	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
THEBA_RS06785	COG0737	Belongs to the 5'-nucleotidase family
THEBA_RS06790	COG4656	Part of a membrane complex involved in electron transport
THEBA_RS06795	COG4658	electron transport chain
THEBA_RS06805	COG4660	Part of a membrane complex involved in electron transport
THEBA_RS06810	COG4657	Part of a membrane complex involved in electron transport
THEBA_RS06815	COG1245	4Fe-4S binding domain
THEBA_RS06815	COG2878	Part of a membrane complex involved in electron transport
THEBA_RS06820	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
THEBA_RS06825	COG0750	zinc metalloprotease
THEBA_RS06830	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
THEBA_RS06835	COG0039	L-malate dehydrogenase activity
THEBA_RS06850	COG0745	RESPONSE REGULATOR receiver
THEBA_RS06855	COG5002	protein histidine kinase activity
THEBA_RS06865	COG0737	Belongs to the 5'-nucleotidase family
THEBA_RS06885	COG1307	EDD domain protein, DegV family
THEBA_RS06895	COG0300	oxidoreductase activity
THEBA_RS06905	COG1473	amidohydrolase
THEBA_RS06920	COG1846	Transcriptional regulator
THEBA_RS06925	COG0386	Belongs to the glutathione peroxidase family
THEBA_RS06935	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
THEBA_RS06935	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
THEBA_RS06940	COG0281	malic enzyme
THEBA_RS06945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
THEBA_RS06950	COG3426	butyrate kinase activity
THEBA_RS06955	COG0280	phosphate acetyltransferase
THEBA_RS06960	COG3426	butyrate kinase activity
THEBA_RS07020	COG0657	acetylesterase activity
THEBA_RS07025	COG1151	hydroxylamine reductase activity
THEBA_RS07050	COG2115	Belongs to the xylose isomerase family
THEBA_RS07055	COG1070	Carbohydrate kinase
THEBA_RS07060	COG1940	carbohydrate kinase activity
THEBA_RS07100	COG0183	Belongs to the thiolase family
THEBA_RS07105	COG0427	acetyl-CoA hydrolase
THEBA_RS07115	COG1028	Short-chain dehydrogenase reductase Sdr
THEBA_RS07120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
THEBA_RS07125	COG2267	carboxylic ester hydrolase activity
THEBA_RS07140	COG0673	inositol 2-dehydrogenase activity
THEBA_RS07145	COG0673	inositol 2-dehydrogenase activity
THEBA_RS07185	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
THEBA_RS07245	COG0395	ABC-type sugar transport system, permease component
THEBA_RS07250	COG0626	cystathionine gamma-synthase activity
THEBA_RS07260	COG1940	carbohydrate kinase activity
THEBA_RS07265	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
THEBA_RS07275	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
THEBA_RS07275	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
THEBA_RS07285	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
THEBA_RS07285	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
THEBA_RS07295	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
THEBA_RS07300	COG1480	7TM receptor with intracellular HD hydrolase
THEBA_RS07305	COG1702	phosphate starvation-inducible protein PhoH
THEBA_RS07310	COG3829	transcription factor binding
THEBA_RS07315	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
THEBA_RS07335	COG1918	ferrous iron import across plasma membrane
THEBA_RS07335	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
THEBA_RS07345	COG0745	RESPONSE REGULATOR receiver
THEBA_RS07350	COG0569	domain protein
THEBA_RS07355	COG0569	domain protein
THEBA_RS07360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
THEBA_RS07365	COG0124	histidyl-tRNA synthetase
THEBA_RS07375	COG1543	Belongs to the glycosyl hydrolase 57 family
THEBA_RS07390	COG0572	uridine kinase
THEBA_RS07395	COG1937	Protein conserved in bacteria
THEBA_RS07405	COG0793	Belongs to the peptidase S41A family
THEBA_RS07425	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
THEBA_RS07430	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
THEBA_RS07440	COG2313	pseudouridylate synthase activity
THEBA_RS07445	COG1574	metal-dependent hydrolase with the TIM-barrel fold
THEBA_RS07455	COG0445	tRNA wobble uridine modification
THEBA_RS07460	COG0511	ligase activity, forming carbon-carbon bonds
THEBA_RS07460	COG5016	pyruvate
THEBA_RS07465	COG2182	Extracellular solute-binding protein
THEBA_RS07470	COG1175	transmembrane transport
THEBA_RS07475	COG3833	ABC-type maltose transport systems, permease component
THEBA_RS07485	COG1214	PFAM Peptidase M22, glycoprotease
THEBA_RS07490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
THEBA_RS07495	COG0484	heat shock protein binding
THEBA_RS07500	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
THEBA_RS07510	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
THEBA_RS07515	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
THEBA_RS07520	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
THEBA_RS07530	COG0772	Belongs to the SEDS family
THEBA_RS07535	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
THEBA_RS07540	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
THEBA_RS07550	COG1363	Peptidase, m42
THEBA_RS07555	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
THEBA_RS07555	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
THEBA_RS07560	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
THEBA_RS07565	COG1703	isobutyryl-CoA mutase activity
THEBA_RS07575	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
THEBA_RS07585	COG0511	ligase activity, forming carbon-carbon bonds
THEBA_RS07600	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
THEBA_RS07615	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
THEBA_RS07615	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
THEBA_RS07635	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
THEBA_RS07645	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
THEBA_RS07650	COG3328	transposase activity
THEBA_RS07690	COG0501	Belongs to the peptidase M48B family
THEBA_RS07695	COG1704	LemA family
THEBA_RS07700	COG0647	UMP catabolic process
THEBA_RS07715	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
THEBA_RS07720	COG0673	inositol 2-dehydrogenase activity
THEBA_RS07725	COG0626	cystathionine gamma-synthase activity
THEBA_RS07730	COG3345	alpha-galactosidase
THEBA_RS07735	COG0366	Alpha amylase catalytic
THEBA_RS07740	COG0697	spore germination
THEBA_RS07770	COG1254	Belongs to the acylphosphatase family
THEBA_RS07775	COG1418	mRNA catabolic process
THEBA_RS07780	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
THEBA_RS07785	COG0242	peptide deformylase activity
THEBA_RS07790	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
THEBA_RS07805	COG1199	ATP-dependent helicase activity
THEBA_RS07820	COG0438	transferase activity, transferring glycosyl groups
THEBA_RS07855	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
THEBA_RS07860	COG2176	DNA-directed DNA polymerase activity
THEBA_RS07870	COG1129	ABC transporter
THEBA_RS07905	COG3706	GGDEF domain
THEBA_RS07910	COG3706	GGDEF domain
THEBA_RS07920	COG1874	Beta-galactosidase
THEBA_RS07920	COG0366	Alpha amylase catalytic
THEBA_RS07930	COG1136	(ABC) transporter
THEBA_RS07945	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
THEBA_RS07955	COG0009	L-threonylcarbamoyladenylate synthase
THEBA_RS08015	COG3328	transposase activity
THEBA_RS08040	COG0395	ABC-type sugar transport system, permease component
THEBA_RS08045	COG1175	transmembrane transport
THEBA_RS08120	COG0514	ATP-dependent DNA helicase (RecQ)
THEBA_RS08130	COG3337	CRISPR-associated protein (Cas_Cmr5)
THEBA_RS08160	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
THEBA_RS08175	COG1518	maintenance of DNA repeat elements
THEBA_RS08215	COG0085	RNA polymerase activity
THEBA_RS08225	COG3604	Transcriptional regulator
THEBA_RS08235	COG3344	reverse transcriptase
THEBA_RS08240	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
THEBA_RS08245	COG1609	Transcriptional regulator
THEBA_RS08255	COG4608	Belongs to the ABC transporter superfamily
THEBA_RS08260	COG0444	Belongs to the ABC transporter superfamily
THEBA_RS08270	COG0601	transmembrane transport
THEBA_RS08285	COG0395	ABC-type sugar transport system, permease component
THEBA_RS08305	COG1609	Transcriptional regulator
THEBA_RS08310	COG2188	Transcriptional regulator
THEBA_RS08315	COG0434	BtpA family
THEBA_RS08320	COG0434	BtpA family
THEBA_RS08335	COG3845	ABC transporter
THEBA_RS08340	COG4603	Belongs to the binding-protein-dependent transport system permease family
THEBA_RS08345	COG1079	Belongs to the binding-protein-dependent transport system permease family
THEBA_RS08390	COG5012	cobalamin binding
THEBA_RS08405	COG3177	Filamentation induced by cAMP protein fic
THEBA_RS08445	COG1785	Belongs to the alkaline phosphatase family
THEBA_RS08465	COG0577	efflux transmembrane transporter activity
THEBA_RS08470	COG0577	efflux transmembrane transporter activity
THEBA_RS08470	COG1136	(ABC) transporter
THEBA_RS08475	COG5002	protein histidine kinase activity
THEBA_RS08480	COG0745	RESPONSE REGULATOR receiver
THEBA_RS08490	COG3328	transposase activity
THEBA_RS08505	COG3119	arylsulfatase activity
THEBA_RS08510	COG0641	radical SAM
THEBA_RS08525	COG0640	Transcriptional regulator
THEBA_RS08530	COG1131	(ABC) transporter
THEBA_RS08540	COG3706	GGDEF domain
THEBA_RS08550	COG2116	formate transmembrane transporter activity
THEBA_RS08580	COG1028	Short-chain dehydrogenase reductase Sdr
THEBA_RS08585	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
THEBA_RS08590	COG0395	ABC-type sugar transport system, permease component
THEBA_RS08595	COG1175	transmembrane transport
THEBA_RS08605	COG2188	Transcriptional regulator
THEBA_RS08610	COG3328	transposase activity
THEBA_RS08615	COG3344	reverse transcriptase
THEBA_RS08620	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
THEBA_RS08625	COG1609	Transcriptional regulator
THEBA_RS08635	COG4608	Belongs to the ABC transporter superfamily
THEBA_RS08640	COG0444	Belongs to the ABC transporter superfamily
THEBA_RS08650	COG0601	transmembrane transport
THEBA_RS08665	COG0395	ABC-type sugar transport system, permease component
THEBA_RS08685	COG1609	Transcriptional regulator
THEBA_RS08690	COG2188	Transcriptional regulator
THEBA_RS08695	COG0434	BtpA family
THEBA_RS08700	COG0434	BtpA family
THEBA_RS08715	COG3845	ABC transporter
THEBA_RS08720	COG4603	Belongs to the binding-protein-dependent transport system permease family
THEBA_RS08725	COG1079	Belongs to the binding-protein-dependent transport system permease family
THEBA_RS08745	COG3344	reverse transcriptase
THEBA_RS08750	COG3177	Filamentation induced by cAMP protein fic
THEBA_RS08770	COG1785	Belongs to the alkaline phosphatase family
THEBA_RS08790	COG0577	efflux transmembrane transporter activity
THEBA_RS08795	COG0577	efflux transmembrane transporter activity
THEBA_RS08795	COG1136	(ABC) transporter
THEBA_RS08800	COG5002	protein histidine kinase activity
THEBA_RS08805	COG0745	RESPONSE REGULATOR receiver
THEBA_RS08815	COG3328	transposase activity
THEBA_RS08830	COG3119	arylsulfatase activity
THEBA_RS08835	COG0641	radical SAM
THEBA_RS08850	COG0640	Transcriptional regulator
THEBA_RS08855	COG1131	(ABC) transporter
THEBA_RS08865	COG3706	GGDEF domain
THEBA_RS08875	COG2116	formate transmembrane transporter activity
THEBA_RS08905	COG1028	Short-chain dehydrogenase reductase Sdr
THEBA_RS08910	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
THEBA_RS08915	COG0395	ABC-type sugar transport system, permease component
THEBA_RS08920	COG1175	transmembrane transport
THEBA_RS08930	COG2188	Transcriptional regulator
THEBA_RS08940	COG3344	reverse transcriptase
THEBA_RS08955	COG0747	negative chemotaxis
THEBA_RS08970	COG1070	Carbohydrate kinase
THEBA_RS08970	COG4806	L-rhamnose isomerase
THEBA_RS08975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
THEBA_RS08990	COG1609	Transcriptional regulator
THEBA_RS09000	COG0800	Aldolase
THEBA_RS09025	COG1863	multisubunit Na H antiporter MnhE subunit
THEBA_RS09030	COG2212	antiporter activity
THEBA_RS09045	COG2111	Na H antiporter
THEBA_RS09045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
THEBA_RS09050	COG1006	Multisubunit Na H antiporter MnhC subunit
THEBA_RS09055	COG0651	ATP synthesis coupled electron transport
THEBA_RS09065	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
THEBA_RS09070	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
THEBA_RS09075	COG0649	NAD binding
THEBA_RS09075	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
THEBA_RS09080	COG0649	NAD binding
THEBA_RS09100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
THEBA_RS09105	COG1335	isochorismatase
THEBA_RS09120	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
THEBA_RS09130	COG0446	pyridine nucleotide-disulphide oxidoreductase
THEBA_RS09135	COG0588	phosphoglycerate mutase activity
THEBA_RS09140	COG2746	aminoglycoside 3-N-acetyltransferase activity
THEBA_RS09155	COG3548	integral membrane protein
THEBA_RS09170	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
THEBA_RS09175	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
THEBA_RS09180	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
THEBA_RS09185	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
THEBA_RS09190	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
THEBA_RS09190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
THEBA_RS09195	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
THEBA_RS09230	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
THEBA_RS09235	COG2183	response to ionizing radiation
THEBA_RS09240	COG0469	pyruvate kinase activity
THEBA_RS09245	COG2199	diguanylate cyclase activity
THEBA_RS09245	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
THEBA_RS09255	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
THEBA_RS09275	COG1446	asparaginase
THEBA_RS09285	COG1840	ABC-type Fe3 transport system, periplasmic component
THEBA_RS09295	COG3842	ATPase activity
THEBA_RS09305	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
THEBA_RS09335	COG1937	Protein conserved in bacteria
THEBA_RS09345	COG2217	Heavy metal translocating P-type atpase
THEBA_RS09355	COG0693	protein deglycase activity
THEBA_RS09365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
THEBA_RS09370	COG1490	D-aminoacyl-tRNA deacylase activity
THEBA_RS09380	COG1137	ATPase activity
THEBA_RS09390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
THEBA_RS09405	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
THEBA_RS09410	COG0720	synthase
THEBA_RS09425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
THEBA_RS09445	COG1132	(ABC) transporter
THEBA_RS09450	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
THEBA_RS09485	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
THEBA_RS09500	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
THEBA_RS09505	COG3956	TIGRFAM MazG family protein
THEBA_RS09515	COG2151	metal-sulfur cluster biosynthetic enzyme
THEBA_RS09520	COG2890	protein-(glutamine-N5) methyltransferase activity
THEBA_RS09525	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
THEBA_RS09535	COG0180	Tryptophanyl-tRNA synthetase
THEBA_RS09540	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
THEBA_RS09545	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
THEBA_RS09550	COG1187	pseudouridine synthase activity
THEBA_RS09570	COG1175	transmembrane transport
THEBA_RS09580	COG1609	Transcriptional regulator
THEBA_RS09600	COG1530	ribonuclease E activity
THEBA_RS09605	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
THEBA_RS09615	COG0606	chelatase, subunit chli
THEBA_RS09625	COG1476	TRANSCRIPTIONal
THEBA_RS09675	COG0622	Phosphoesterase
THEBA_RS09705	COG0655	NAD(P)H dehydrogenase (quinone) activity
THEBA_RS09735	COG0803	Belongs to the bacterial solute-binding protein 9 family
THEBA_RS09740	COG1121	(ABC) transporter
THEBA_RS09745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
THEBA_RS09750	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
THEBA_RS09765	COG4608	Belongs to the ABC transporter superfamily
THEBA_RS09770	COG0444	Belongs to the ABC transporter superfamily
THEBA_RS09775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THEBA_RS09780	COG0601	transmembrane transport
THEBA_RS09790	COG2267	carboxylic ester hydrolase activity
THEBA_RS09805	COG0739	heme binding
THEBA_RS09810	COG0095	Lipoate-protein ligase
THEBA_RS09815	COG1013	pyruvate-flavodoxin oxidoreductase activity
THEBA_RS09815	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
THEBA_RS09815	COG0674	pyruvate-flavodoxin oxidoreductase activity
THEBA_RS09815	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
THEBA_RS09825	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
THEBA_RS09830	COG1285	pathogenesis
THEBA_RS09840	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
THEBA_RS09845	COG0492	ferredoxin-NADP+ reductase activity
THEBA_RS09855	COG1752	Esterase of the alpha-beta hydrolase superfamily
THEBA_RS09940	COG0546	phosphoglycolate phosphatase activity
THEBA_RS09945	COG0546	phosphoglycolate phosphatase activity
THEBA_RS09950	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
THEBA_RS09965	COG0495	leucyl-tRNA aminoacylation
THEBA_RS09980	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
THEBA_RS09985	COG1136	(ABC) transporter
THEBA_RS09990	COG1136	(ABC) transporter
THEBA_RS09990	COG0577	efflux transmembrane transporter activity
THEBA_RS10000	COG0656	L-ascorbic acid biosynthetic process
THEBA_RS10010	COG0450	alkyl hydroperoxide reductase
THEBA_RS10015	COG1653	transport
THEBA_RS10020	COG1175	transmembrane transport
THEBA_RS10025	COG0395	ABC-type sugar transport system, permease component
THEBA_RS10030	COG0463	Glycosyl transferase, family 2
THEBA_RS10035	COG1737	Transcriptional regulator
THEBA_RS10045	COG5002	protein histidine kinase activity
THEBA_RS10055	COG0704	Plays a role in the regulation of phosphate uptake
THEBA_RS10065	COG0581	inorganic phosphate transmembrane transporter activity
THEBA_RS10070	COG0573	inorganic phosphate transmembrane transporter activity
THEBA_RS10075	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
THEBA_RS10090	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
THEBA_RS10095	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
THEBA_RS10130	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
THEBA_RS10160	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
THEBA_RS10165	COG0438	transferase activity, transferring glycosyl groups
THEBA_RS10170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
THEBA_RS10185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
THEBA_RS10210	COG1131	(ABC) transporter
THEBA_RS10220	COG3481	metal-dependent phosphohydrolase, HD sub domain
THEBA_RS10225	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
THEBA_RS10230	COG2723	6-phospho-beta-galactosidase activity
THEBA_RS10235	COG1307	EDD domain protein, DegV family
THEBA_RS10245	COG2195	Cleaves the N-terminal amino acid of tripeptides
THEBA_RS10250	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
THEBA_RS10255	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
THEBA_RS10270	COG0488	(ABC) transporter
THEBA_RS10290	COG2234	aminopeptidase activity
THEBA_RS10300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
THEBA_RS10310	COG2033	superoxide reductase activity
THEBA_RS10325	COG0542	response to heat
THEBA_RS10330	COG0071	Belongs to the small heat shock protein (HSP20) family
THEBA_RS10335	COG0443	Heat shock 70 kDa protein
THEBA_RS10380	COG1609	Transcriptional regulator
THEBA_RS10385	COG1129	ABC transporter
THEBA_RS10390	COG1172	Belongs to the binding-protein-dependent transport system permease family
THEBA_RS10395	COG1879	ABC-type sugar transport system periplasmic component
THEBA_RS10420	COG1879	ABC-type sugar transport system periplasmic component
THEBA_RS10425	COG1172	Belongs to the binding-protein-dependent transport system permease family
THEBA_RS10430	COG1129	ABC transporter
THEBA_RS10440	COG0673	inositol 2-dehydrogenase activity
THEBA_RS10465	COG1879	ABC-type sugar transport system periplasmic component
THEBA_RS10470	COG1172	Belongs to the binding-protein-dependent transport system permease family
THEBA_RS10475	COG1129	ABC transporter
THEBA_RS10480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
THEBA_RS10490	COG1869	D-ribose catabolic process
THEBA_RS10495	COG1609	Transcriptional regulator
THEBA_RS10510	COG1597	lipid kinase activity
THEBA_RS10515	COG5012	cobalamin binding
THEBA_RS10520	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
THEBA_RS10525	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
THEBA_RS10535	COG2030	dehydratase
THEBA_RS10545	COG0604	alcohol dehydrogenase
THEBA_RS10550	COG3246	L-lysine catabolic process to acetate
THEBA_RS10555	COG1607	acyl-coa hydrolase
THEBA_RS10565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
THEBA_RS10570	COG0534	Mate efflux family protein
THEBA_RS10585	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
THEBA_RS10590	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
THEBA_RS10595	COG0215	cysteine-tRNA ligase activity
THEBA_RS10615	COG0405	Gamma-glutamyltransferase
THEBA_RS10620	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
THEBA_RS10640	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
THEBA_RS10655	COG0601	transmembrane transport
THEBA_RS10660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THEBA_RS10665	COG0444	Belongs to the ABC transporter superfamily
THEBA_RS10670	COG4608	Belongs to the ABC transporter superfamily
THEBA_RS10675	COG1073	alpha beta
THEBA_RS10685	COG4555	ABC transporter
THEBA_RS10705	COG2217	Heavy metal translocating P-type atpase
THEBA_RS10750	COG1509	lysine 2,3-aminomutase activity
THEBA_RS10765	COG0667	Aldo Keto reductase
THEBA_RS10775	COG1012	belongs to the aldehyde dehydrogenase family
THEBA_RS10780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
THEBA_RS10800	COG0584	glycerophosphoryl diester phosphodiesterase
THEBA_RS10820	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
THEBA_RS10825	COG2059	Chromate
THEBA_RS10845	COG1136	(ABC) transporter
THEBA_RS10870	COG0488	(ABC) transporter
THEBA_RS10880	COG4608	Belongs to the ABC transporter superfamily
THEBA_RS10890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THEBA_RS10900	COG0747	negative chemotaxis
THEBA_RS10905	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
THEBA_RS10925	COG1120	ATPase activity
THEBA_RS10930	COG4139	cobalamin transport
THEBA_RS10935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
THEBA_RS10940	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
THEBA_RS10945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
THEBA_RS10950	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
THEBA_RS10955	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
THEBA_RS10960	COG0575	Belongs to the CDS family
THEBA_RS10965	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
THEBA_RS10970	COG0233	cytoplasmic translational termination
THEBA_RS10975	COG1862	Preprotein translocase
THEBA_RS10980	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
THEBA_RS10985	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
THEBA_RS11000	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
THEBA_RS11000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
THEBA_RS11015	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
THEBA_RS11020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
THEBA_RS11025	COG0509	glycine decarboxylation via glycine cleavage system
THEBA_RS11040	COG0205	6-phosphofructokinase activity
THEBA_RS11045	COG0469	pyruvate kinase activity
THEBA_RS11050	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
THEBA_RS11055	COG0459	protein refolding
THEBA_RS11075	COG3864	Putative metallopeptidase domain
THEBA_RS11115	COG3534	alpha-L-arabinofuranosidase
THEBA_RS11130	COG0395	ABC-type sugar transport system, permease component
THEBA_RS11135	COG1175	transmembrane transport
THEBA_RS11155	COG1309	transcriptional regulator
THEBA_RS11170	COG0673	inositol 2-dehydrogenase activity
THEBA_RS11175	COG1082	Xylose isomerase domain protein TIM barrel
THEBA_RS11180	COG1063	alcohol dehydrogenase
THEBA_RS11185	COG0395	ABC-type sugar transport system, permease component
THEBA_RS11190	COG1175	transmembrane transport
THEBA_RS11200	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
THEBA_RS11205	COG2188	Transcriptional regulator
THEBA_RS11225	COG1129	ABC transporter
THEBA_RS11230	COG1172	Belongs to the binding-protein-dependent transport system permease family
THEBA_RS11250	COG1446	asparaginase
THEBA_RS11275	COG4999	Histidine kinase
THEBA_RS11275	COG2205	protein histidine kinase activity
THEBA_RS11275	COG3850	Histidine kinase
THEBA_RS11275	COG3437	response regulator, receiver
THEBA_RS11280	COG5001	Diguanylate cyclase
THEBA_RS11290	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
THEBA_RS11305	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
THEBA_RS11315	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
THEBA_RS11345	COG3447	MASE1 domain protein
THEBA_RS11345	COG5002	protein histidine kinase activity
THEBA_RS11345	COG5001	Diguanylate cyclase
THEBA_RS11350	COG4608	Belongs to the ABC transporter superfamily
THEBA_RS11355	COG0444	Belongs to the ABC transporter superfamily
THEBA_RS11360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THEBA_RS11365	COG0601	transmembrane transport
THEBA_RS11380	COG2271	Major facilitator Superfamily
THEBA_RS11390	COG3457	Alanine racemase
THEBA_RS11395	COG1172	Belongs to the binding-protein-dependent transport system permease family
THEBA_RS11400	COG1129	ABC transporter
THEBA_RS11415	COG1940	carbohydrate kinase activity
THEBA_RS11460	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
THEBA_RS11465	COG1518	maintenance of DNA repeat elements
THEBA_RS11540	COG3328	transposase activity
THEBA_RS11565	COG1396	sequence-specific DNA binding
THEBA_RS11615	COG0534	Mate efflux family protein
THEBA_RS11630	COG1794	racemase activity, acting on amino acids and derivatives
THEBA_RS11645	COG1067	ATP-dependent peptidase activity
THEBA_RS11660	COG1131	(ABC) transporter
THEBA_RS11670	COG2199	diguanylate cyclase activity
THEBA_RS11670	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
THEBA_RS11685	COG0531	amino acid
THEBA_RS11730	COG1414	Transcriptional regulator
THEBA_RS11745	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
THEBA_RS11750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
THEBA_RS11780	COG4209	transmembrane transport
THEBA_RS11785	COG0395	ABC-type sugar transport system, permease component
THEBA_RS11795	COG1605	Chorismate mutase
THEBA_RS11795	COG0077	Prephenate dehydratase
THEBA_RS11820	COG4221	oxidoreductase activity
THEBA_RS11870	COG1695	Transcriptional regulator
THEBA_RS11905	COG1660	Displays ATPase and GTPase activities
THEBA_RS11915	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
THEBA_RS11920	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
THEBA_RS11935	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
THEBA_RS11940	COG1592	Rubrerythrin
THEBA_RS11955	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
THEBA_RS11990	COG1006	Multisubunit Na H antiporter MnhC subunit
THEBA_RS11995	COG0651	ATP synthesis coupled electron transport
THEBA_RS12005	COG0456	acetyltransferase
THEBA_RS12010	COG1254	Belongs to the acylphosphatase family
THEBA_RS12015	COG1073	alpha beta
THEBA_RS12025	COG0601	transmembrane transport
THEBA_RS12030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THEBA_RS12035	COG0444	Belongs to the ABC transporter superfamily
THEBA_RS12040	COG4608	Belongs to the ABC transporter superfamily
THEBA_RS12045	COG3344	reverse transcriptase
THEBA_RS12055	COG1349	DNA-binding transcription factor activity
THEBA_RS12060	COG1172	Belongs to the binding-protein-dependent transport system permease family
THEBA_RS12065	COG1172	Belongs to the binding-protein-dependent transport system permease family
THEBA_RS12070	COG1129	ABC transporter
THEBA_RS12075	COG1879	ABC-type sugar transport system periplasmic component
THEBA_RS12080	COG1070	Carbohydrate kinase
THEBA_RS12085	COG0235	Class ii aldolase
THEBA_RS12090	COG3876	Protein conserved in bacteria
THEBA_RS12095	COG2188	Transcriptional regulator
THEBA_RS12115	COG4948	Mandelate Racemase Muconate Lactonizing
THEBA_RS12120	COG0747	negative chemotaxis
THEBA_RS12125	COG0601	transmembrane transport
THEBA_RS12130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THEBA_RS12135	COG0444	Belongs to the ABC transporter superfamily
THEBA_RS12140	COG4608	Belongs to the ABC transporter superfamily
THEBA_RS12145	COG0697	spore germination
THEBA_RS12195	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
THEBA_RS12250	COG2515	1-aminocyclopropane-1-carboxylate deaminase
THEBA_RS12255	COG0501	Belongs to the peptidase M48B family
THEBA_RS12265	COG0668	transmembrane transport
THEBA_RS12270	COG1174	glycine betaine transport
THEBA_RS12280	COG1174	glycine betaine transport
THEBA_RS12285	COG1732	Glycine betaine
THEBA_RS12290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
THEBA_RS12295	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
THEBA_RS12300	COG0668	transmembrane transport
THEBA_RS12325	COG0395	ABC-type sugar transport system, permease component
THEBA_RS12330	COG1175	transmembrane transport
THEBA_RS12345	COG0395	ABC-type sugar transport system, permease component
THEBA_RS12365	COG3459	Glycosyltransferase 36 associated
THEBA_RS12380	COG1609	Transcriptional regulator
THEBA_RS12405	COG0731	radical SAM domain protein
THEBA_RS12405	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
THEBA_RS12450	COG2964	Protein conserved in bacteria
THEBA_RS12460	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
THEBA_RS12465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
THEBA_RS12470	COG0737	Belongs to the 5'-nucleotidase family
THEBA_RS12480	COG0321	lipoyl(octanoyl) transferase activity
THEBA_RS12485	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
THEBA_RS12495	COG1028	Short-chain dehydrogenase reductase Sdr
THEBA_RS12520	COG1105	Belongs to the carbohydrate kinase PfkB family
THEBA_RS12595	COG1129	ABC transporter
THEBA_RS12600	COG2207	Transcriptional regulator
THEBA_RS12600	COG4753	response regulator
THEBA_RS12615	COG1172	Belongs to the binding-protein-dependent transport system permease family
THEBA_RS12620	COG1172	Belongs to the binding-protein-dependent transport system permease family
THEBA_RS12630	COG2376	Dihydroxyacetone kinase
THEBA_RS12635	COG1461	Dihydroxyacetone kinase
THEBA_RS12650	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
THEBA_RS12655	COG1233	COG1233 Phytoene dehydrogenase and related
THEBA_RS12675	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
THEBA_RS12680	COG1070	Carbohydrate kinase
THEBA_RS12685	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
THEBA_RS12690	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
THEBA_RS12735	COG0534	Mate efflux family protein
THEBA_RS12765	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
THEBA_RS12775	COG1461	Dihydroxyacetone kinase
THEBA_RS12780	COG1278	Cold shock
THEBA_RS12795	COG0714	Associated with various cellular activities
THEBA_RS12800	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
THEBA_RS12805	COG1177	transmembrane transport
THEBA_RS12810	COG1176	ABC-type spermidine putrescine transport system, permease component I
THEBA_RS12815	COG3842	ATPase activity
THEBA_RS12860	COG0277	FAD linked oxidase domain protein
THEBA_RS12870	COG2086	electron transfer activity
THEBA_RS12875	COG3706	GGDEF domain
THEBA_RS12885	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
THEBA_RS12890	COG1129	ABC transporter
THEBA_RS12895	COG1172	Belongs to the binding-protein-dependent transport system permease family
THEBA_RS12900	COG0346	lactoylglutathione lyase activity
THEBA_RS12910	COG1070	Carbohydrate kinase
THEBA_RS12915	COG2188	Transcriptional regulator
THEBA_RS12920	COG1869	D-ribose catabolic process
THEBA_RS12925	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
THEBA_RS12930	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
THEBA_RS12935	COG0667	Aldo Keto reductase
THEBA_RS12940	COG1063	alcohol dehydrogenase
THEBA_RS12960	COG4608	Belongs to the ABC transporter superfamily
THEBA_RS12965	COG0444	Belongs to the ABC transporter superfamily
THEBA_RS12970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THEBA_RS12975	COG0601	transmembrane transport
THEBA_RS12980	COG0747	negative chemotaxis
THEBA_RS12985	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
THEBA_RS12990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
THEBA_RS13000	COG1472	Belongs to the glycosyl hydrolase 3 family
THEBA_RS13005	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
THEBA_RS13010	COG2188	Transcriptional regulator
THEBA_RS13020	COG3876	Protein conserved in bacteria
THEBA_RS13025	COG0395	ABC-type sugar transport system, permease component
THEBA_RS13030	COG1175	transmembrane transport
THEBA_RS13035	COG2182	Extracellular solute-binding protein
THEBA_RS13050	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
THEBA_RS13055	COG1272	protein, Hemolysin III
THEBA_RS13060	COG1609	Transcriptional regulator
THEBA_RS13065	COG1653	transport
THEBA_RS13070	COG1175	transmembrane transport
THEBA_RS13075	COG0395	ABC-type sugar transport system, permease component
THEBA_RS13090	COG3250	beta-galactosidase activity
THEBA_RS13100	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
THEBA_RS13125	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
THEBA_RS13170	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
THEBA_RS13180	COG1131	(ABC) transporter
THEBA_RS13210	COG0745	RESPONSE REGULATOR receiver
THEBA_RS13215	COG2205	protein histidine kinase activity
THEBA_RS13220	COG0436	Aminotransferase
THEBA_RS13230	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
THEBA_RS13235	COG1132	(ABC) transporter
THEBA_RS13250	COG2814	Major facilitator Superfamily
THEBA_RS13260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
THEBA_RS13305	COG2011	ABC-type metal ion transport system permease component
THEBA_RS13310	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
THEBA_RS13315	COG1464	Belongs to the NlpA lipoprotein family
THEBA_RS13340	COG0420	3'-5' exonuclease activity
THEBA_RS13345	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
THEBA_RS13365	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
THEBA_RS13380	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
THEBA_RS13385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
THEBA_RS13390	COG2721	sulfolactate sulfo-lyase activity
THEBA_RS13410	COG0280	phosphate acetyltransferase
THEBA_RS13415	COG3426	butyrate kinase activity
THEBA_RS13420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
THEBA_RS13435	COG0411	ABC transporter
THEBA_RS13445	COG0559	Belongs to the binding-protein-dependent transport system permease family
THEBA_RS13450	COG0683	leucine binding
THEBA_RS13465	COG0251	oxidation-reduction process
THEBA_RS13470	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
THEBA_RS13475	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
THEBA_RS13480	COG1529	Aldehyde oxidase and xanthine dehydrogenase
THEBA_RS13500	COG0395	ABC-type sugar transport system, permease component
THEBA_RS13505	COG1368	sulfuric ester hydrolase activity
THEBA_RS13550	COG1392	Phosphate transport regulator
THEBA_RS13555	COG0306	phosphate transporter
THEBA_RS13560	COG1408	metallophosphoesterase
THEBA_RS13565	COG1215	transferase activity, transferring glycosyl groups
THEBA_RS13570	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
THEBA_RS13580	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
THEBA_RS13590	COG1971	Probably functions as a manganese efflux pump
THEBA_RS13600	COG2267	carboxylic ester hydrolase activity
THEBA_RS13620	COG1609	Transcriptional regulator
THEBA_RS13630	COG1175	transmembrane transport
THEBA_RS13635	COG0395	ABC-type sugar transport system, permease component
THEBA_RS13665	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
THEBA_RS13670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
THEBA_RS13675	COG1141	Ferredoxin
THEBA_RS13700	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
THEBA_RS13730	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
THEBA_RS13750	COG1216	Glycosyl transferase, family 2