locus-tag	class	description
MVOL_RS00015	COG0539	negative regulation of cytoplasmic translation
MVOL_RS00045	COG4974	Belongs to the 'phage' integrase family
MVOL_RS00115	COG2113	Glycine betaine
MVOL_RS00125	COG3448	diguanylate cyclase activity
MVOL_RS00125	COG4175	Glycine betaine
MVOL_RS00135	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MVOL_RS00145	COG0426	domain, Protein
MVOL_RS00150	COG0301	tRNA thio-modification
MVOL_RS00175	COG0419	ATPase involved in DNA repair
MVOL_RS00190	COG1053	succinate dehydrogenase
MVOL_RS00200	COG0519	Catalyzes the synthesis of GMP from XMP
MVOL_RS00200	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MVOL_RS00205	COG0504	CTP synthase activity
MVOL_RS00225	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MVOL_RS00245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MVOL_RS00260	COG0166	Belongs to the GPI family
MVOL_RS00290	COG1013	pyruvate-flavodoxin oxidoreductase activity
MVOL_RS00335	COG0667	Aldo Keto reductase
MVOL_RS00345	COG0310	cobalt ion transport
MVOL_RS00410	COG2113	Glycine betaine
MVOL_RS00420	COG4175	Glycine betaine
MVOL_RS00420	COG3448	diguanylate cyclase activity
MVOL_RS00430	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MVOL_RS00440	COG0426	domain, Protein
MVOL_RS00445	COG0301	tRNA thio-modification
MVOL_RS00470	COG0419	ATPase involved in DNA repair
MVOL_RS00485	COG1053	succinate dehydrogenase
MVOL_RS00495	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MVOL_RS00495	COG0519	Catalyzes the synthesis of GMP from XMP
MVOL_RS00500	COG0504	CTP synthase activity
MVOL_RS00520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MVOL_RS00540	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MVOL_RS00555	COG0166	Belongs to the GPI family
MVOL_RS00585	COG1013	pyruvate-flavodoxin oxidoreductase activity
MVOL_RS00630	COG0667	Aldo Keto reductase
MVOL_RS00640	COG0310	cobalt ion transport
MVOL_RS00645	COG0733	neurotransmitter:sodium symporter activity
MVOL_RS00665	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MVOL_RS00670	COG0181	hydroxymethylbilane synthase activity
MVOL_RS00690	COG0077	Prephenate dehydratase
MVOL_RS00690	COG1605	Chorismate mutase
MVOL_RS00700	COG2894	cell division
MVOL_RS00705	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MVOL_RS00755	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MVOL_RS00785	COG0616	signal peptide processing
MVOL_RS00790	COG1606	tRNA processing
MVOL_RS00800	COG1968	undecaprenyl-diphosphatase activity
MVOL_RS00825	COG1846	Transcriptional regulator
MVOL_RS00840	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MVOL_RS00875	COG0157	Belongs to the NadC ModD family
MVOL_RS00880	COG0585	pseudouridine synthase activity
MVOL_RS00915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MVOL_RS00930	COG0765	amino acid transport
MVOL_RS00950	COG1269	ATP hydrolysis coupled proton transport
MVOL_RS00970	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
MVOL_RS00985	COG1394	ATPase activity, coupled to movement of substances
MVOL_RS00995	COG1793	dna ligase
MVOL_RS01015	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MVOL_RS01030	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MVOL_RS01055	COG0574	Belongs to the PEP-utilizing enzyme family
MVOL_RS01055	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MVOL_RS01060	COG3959	Transketolase, thiamine diphosphate binding domain
MVOL_RS01065	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MVOL_RS01070	COG3958	Transketolase
MVOL_RS01110	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MVOL_RS01115	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MVOL_RS01130	COG0200	Binds to the 23S rRNA
MVOL_RS01135	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MVOL_RS01140	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MVOL_RS01155	COG0148	phosphopyruvate hydratase activity
MVOL_RS01175	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MVOL_RS01180	COG0673	inositol 2-dehydrogenase activity
MVOL_RS01210	COG0482	sulfurtransferase activity
MVOL_RS01225	COG0438	transferase activity, transferring glycosyl groups
MVOL_RS01250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MVOL_RS01260	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MVOL_RS01265	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MVOL_RS01275	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MVOL_RS01295	COG0019	diaminopimelate decarboxylase activity
MVOL_RS01320	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MVOL_RS01340	COG0012	GTP binding
MVOL_RS01345	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MVOL_RS01375	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MVOL_RS01385	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MVOL_RS01390	COG0252	asparaginase activity
MVOL_RS01405	COG0028	Belongs to the TPP enzyme family
MVOL_RS01410	COG0440	acetolactate synthase activity
MVOL_RS01430	COG0189	ligase activity
MVOL_RS01440	COG0489	protein tyrosine kinase activity
MVOL_RS01475	COG0047	phosphoribosylformylglycinamidine synthase activity
MVOL_RS01495	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MVOL_RS01505	COG4974	Belongs to the 'phage' integrase family
MVOL_RS01625	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MVOL_RS01675	COG4974	Belongs to the 'phage' integrase family
MVOL_RS01690	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MVOL_RS01695	COG1301	dicarboxylic acid transport
MVOL_RS01705	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MVOL_RS01705	COG0517	IMP dehydrogenase activity
MVOL_RS01725	COG1592	Rubrerythrin
MVOL_RS01750	COG0530	calcium, potassium:sodium antiporter activity
MVOL_RS01800	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MVOL_RS01805	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MVOL_RS01815	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MVOL_RS01820	COG0708	Exodeoxyribonuclease III
MVOL_RS01830	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MVOL_RS01865	COG1830	Aldolase
MVOL_RS01875	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MVOL_RS01885	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MVOL_RS01895	COG1476	TRANSCRIPTIONal
MVOL_RS01905	COG0697	spore germination
MVOL_RS01915	COG1757	Na H antiporter
MVOL_RS01925	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
MVOL_RS01935	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MVOL_RS01950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MVOL_RS01960	COG1522	sequence-specific DNA binding
MVOL_RS01965	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MVOL_RS01980	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
MVOL_RS01985	COG1363	Peptidase, m42
MVOL_RS01995	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MVOL_RS02015	COG0697	spore germination
MVOL_RS02020	COG2813	Specifically methylates the guanine in position
MVOL_RS02115	COG0667	Aldo Keto reductase
MVOL_RS02135	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MVOL_RS02140	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MVOL_RS02155	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MVOL_RS02165	COG1234	tRNA 3'-trailer cleavage
MVOL_RS02195	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MVOL_RS02200	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MVOL_RS02205	COG0789	Transcriptional regulator
MVOL_RS02220	COG1433	Dinitrogenase iron-molybdenum cofactor
MVOL_RS02220	COG0535	radical SAM domain protein
MVOL_RS02230	COG0495	leucyl-tRNA aminoacylation
MVOL_RS02260	COG4974	Belongs to the 'phage' integrase family
MVOL_RS02375	COG4974	Belongs to the 'phage' integrase family
MVOL_RS02565	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MVOL_RS02585	COG1201	RNA secondary structure unwinding
MVOL_RS02710	COG0210	DNA helicase
MVOL_RS02765	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MVOL_RS02770	COG1518	maintenance of DNA repeat elements
MVOL_RS02840	COG0330	HflC and HflK could
MVOL_RS02855	COG0133	tryptophan synthase activity
MVOL_RS02860	COG0135	phosphoribosylanthranilate isomerase activity
MVOL_RS02865	COG0512	Glutamine amidotransferase of anthranilate synthase
MVOL_RS02865	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MVOL_RS02870	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MVOL_RS02875	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MVOL_RS02890	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
MVOL_RS02900	COG3259	Nickel-dependent hydrogenase
MVOL_RS02905	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
MVOL_RS02915	COG3259	Nickel-dependent hydrogenase
MVOL_RS02925	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MVOL_RS02935	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MVOL_RS02940	COG0581	inorganic phosphate transmembrane transporter activity
MVOL_RS02945	COG0573	inorganic phosphate transmembrane transporter activity
MVOL_RS02980	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
MVOL_RS03010	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MVOL_RS03030	COG0318	PFAM AMP-dependent synthetase and ligase
MVOL_RS03035	COG0215	cysteine-tRNA ligase activity
MVOL_RS03165	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
MVOL_RS03175	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MVOL_RS03180	COG0385	Bile acid
MVOL_RS03190	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
MVOL_RS03225	COG0072	phenylalanine-tRNA ligase activity
MVOL_RS03230	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MVOL_RS03235	COG0644	oxidoreductase
MVOL_RS03240	COG0719	Fe-S assembly protein
MVOL_RS03245	COG0396	ATPase activity
MVOL_RS03255	COG0431	NADPH-dependent FMN reductase
MVOL_RS03270	COG1120	ATPase activity
MVOL_RS03275	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
MVOL_RS03275	COG3261	NADH dehydrogenase
MVOL_RS03285	COG0563	adenylate kinase activity
MVOL_RS03295	COG0840	transmembrane signaling receptor activity
MVOL_RS03295	COG3290	protein histidine kinase activity
MVOL_RS03295	COG0840	transmembrane signaling receptor activity
MVOL_RS03295	COG3290	protein histidine kinase activity
MVOL_RS03310	COG2233	PERMEase
MVOL_RS03315	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MVOL_RS03320	COG1201	RNA secondary structure unwinding
MVOL_RS03355	COG0393	Putative heavy-metal-binding
MVOL_RS03370	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
MVOL_RS03375	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
MVOL_RS03385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MVOL_RS03390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MVOL_RS03405	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
MVOL_RS03405	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
MVOL_RS03410	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
MVOL_RS03450	COG0641	radical SAM
MVOL_RS03460	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MVOL_RS03470	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
MVOL_RS03495	COG2264	protein methyltransferase activity
MVOL_RS03505	COG0534	Mate efflux family protein
MVOL_RS03525	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MVOL_RS03550	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MVOL_RS03570	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MVOL_RS03570	COG0674	pyruvate-flavodoxin oxidoreductase activity
MVOL_RS03580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MVOL_RS03590	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MVOL_RS03615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MVOL_RS03620	COG0442	prolyl-tRNA aminoacylation
MVOL_RS03625	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MVOL_RS03650	COG1584	GPR1 FUN34 yaaH family protein
MVOL_RS03655	COG1592	Rubrerythrin
MVOL_RS03655	COG1773	rubredoxin
MVOL_RS03665	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
MVOL_RS03680	COG1229	Formylmethanofuran dehydrogenase subunit A
MVOL_RS03725	COG0303	'Molybdopterin
MVOL_RS03760	COG0131	Imidazoleglycerol-phosphate dehydratase
MVOL_RS03770	COG0284	orotidine-5'-phosphate decarboxylase activity
MVOL_RS03780	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MVOL_RS03795	COG0589	response to stress
MVOL_RS03805	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
MVOL_RS03850	COG2033	superoxide reductase activity
MVOL_RS03860	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MVOL_RS03865	COG1760	l-serine dehydratase
MVOL_RS03875	COG0314	molybdopterin synthase activity
MVOL_RS03880	COG2217	Heavy metal translocating P-type atpase
MVOL_RS03885	COG1324	tolerance protein
MVOL_RS03890	COG0426	domain, Protein
MVOL_RS03905	COG0347	Belongs to the P(II) protein family
MVOL_RS03910	COG0004	ammonium transporteR
MVOL_RS03920	COG0564	pseudouridine synthase activity
MVOL_RS03930	COG0473	3-isopropylmalate dehydrogenase activity
MVOL_RS03945	COG2048	Heterodisulfide reductase, subunit B
MVOL_RS03960	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MVOL_RS03985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MVOL_RS03990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MVOL_RS04010	COG2048	Heterodisulfide reductase, subunit B
MVOL_RS04030	COG0303	'Molybdopterin
MVOL_RS04050	COG0745	RESPONSE REGULATOR receiver
MVOL_RS04055	COG5002	protein histidine kinase activity
MVOL_RS04075	COG0288	reversible hydration of carbon dioxide
MVOL_RS04085	COG2116	formate transmembrane transporter activity
MVOL_RS04095	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MVOL_RS04115	COG0352	thiamine-phosphate diphosphorylase activity
MVOL_RS04125	COG0174	glutamine synthetase
MVOL_RS04135	COG0826	peptidase U32
MVOL_RS04140	COG0113	porphobilinogen synthase activity
MVOL_RS04160	COG0560	Phosphoserine phosphatase
MVOL_RS04195	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MVOL_RS04215	COG2242	protein methyltransferase activity
MVOL_RS04235	COG0552	protein localization to endoplasmic reticulum
MVOL_RS04290	COG2192	nodulation
MVOL_RS04295	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MVOL_RS04310	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MVOL_RS04315	COG1691	(AIR) carboxylase
MVOL_RS04345	COG1229	Formylmethanofuran dehydrogenase subunit A
MVOL_RS04385	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MVOL_RS04390	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MVOL_RS04395	COG3830	Belongs to the UPF0237 family
MVOL_RS04400	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
MVOL_RS04410	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
MVOL_RS04415	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
MVOL_RS04415	COG0778	Nitroreductase
MVOL_RS04420	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MVOL_RS04420	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MVOL_RS04425	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MVOL_RS04445	COG2078	PFAM AMMECR1 domain protein
MVOL_RS04465	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MVOL_RS04470	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MVOL_RS04475	COG0039	L-malate dehydrogenase activity
MVOL_RS04495	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MVOL_RS04500	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MVOL_RS04505	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MVOL_RS04540	COG0052	Belongs to the universal ribosomal protein uS2 family
MVOL_RS04555	COG0598	Magnesium transport protein CorA
MVOL_RS04575	COG0517	IMP dehydrogenase activity
MVOL_RS04575	COG1125	glycine betaine transport
MVOL_RS04580	COG1342	Belongs to the UPF0251 family
MVOL_RS04605	COG0516	GMP reductase activity
MVOL_RS04605	COG0517	IMP dehydrogenase activity
MVOL_RS04615	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MVOL_RS04645	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MVOL_RS04655	COG0710	3-dehydroquinate dehydratase activity
MVOL_RS04665	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MVOL_RS04670	COG0367	asparagine synthase
MVOL_RS04680	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MVOL_RS04695	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MVOL_RS04705	COG0835	chemotaxis
MVOL_RS04710	COG2201	protein-glutamate methylesterase activity
MVOL_RS04715	COG2198	Histidine kinase
MVOL_RS04715	COG0643	Histidine kinase
MVOL_RS04720	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
MVOL_RS04740	COG2201	protein-glutamate methylesterase activity
MVOL_RS04785	COG1196	nuclear chromosome segregation
MVOL_RS04790	COG0436	Aminotransferase
MVOL_RS04805	COG1739	Uncharacterized protein family UPF0029
MVOL_RS04810	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
MVOL_RS04865	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MVOL_RS04935	COG0235	Class ii aldolase
MVOL_RS04955	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MVOL_RS04960	COG0018	arginyl-trna synthetase
MVOL_RS05005	COG2252	PERMEase
MVOL_RS05025	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MVOL_RS05040	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MVOL_RS05055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MVOL_RS05060	COG0051	transcription antitermination factor activity, RNA binding
MVOL_RS05065	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MVOL_RS05085	COG0195	Participates in both transcription termination and antitermination
MVOL_RS05095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MVOL_RS05100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MVOL_RS05105	COG0085	RNA polymerase activity
MVOL_RS05110	COG0085	RNA polymerase activity
MVOL_RS05120	COG0517	IMP dehydrogenase activity
MVOL_RS05120	COG0617	tRNA 3'-terminal CCA addition
MVOL_RS05120	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MVOL_RS05125	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MVOL_RS05135	COG0482	sulfurtransferase activity
MVOL_RS05145	COG0717	Belongs to the dCTP deaminase family
MVOL_RS05160	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MVOL_RS05165	COG0201	protein transport
MVOL_RS05175	COG0200	Binds to the 23S rRNA
MVOL_RS05210	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MVOL_RS05220	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MVOL_RS05235	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MVOL_RS05240	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MVOL_RS05255	COG0255	Belongs to the universal ribosomal protein uL29 family
MVOL_RS05260	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MVOL_RS05265	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MVOL_RS05285	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MVOL_RS05290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MVOL_RS05295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MVOL_RS05310	COG1126	abc transporter atp-binding protein
MVOL_RS05315	COG0765	amino acid transport
MVOL_RS05330	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MVOL_RS05335	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MVOL_RS05340	COG1013	pyruvate-flavodoxin oxidoreductase activity
MVOL_RS05345	COG0674	pyruvate-flavodoxin oxidoreductase activity
MVOL_RS05355	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MVOL_RS05375	COG1115	amino acid carrier protein
MVOL_RS05380	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MVOL_RS05390	COG1242	4 iron, 4 sulfur cluster binding
MVOL_RS05420	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MVOL_RS05435	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MVOL_RS05440	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MVOL_RS05445	COG0312	modulator of DNA gyrase
MVOL_RS05450	COG0436	Aminotransferase
MVOL_RS05455	COG0077	Prephenate dehydratase
MVOL_RS05455	COG1605	Chorismate mutase
MVOL_RS05470	COG2144	transferase activity, transferring acyl groups
MVOL_RS05475	COG0126	phosphoglycerate kinase activity
MVOL_RS05550	COG0089	rRNA binding
MVOL_RS05560	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MVOL_RS05575	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MVOL_RS05580	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MVOL_RS05585	COG0163	prenyltransferase activity
MVOL_RS05665	COG1962	PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit
MVOL_RS05680	COG0084	hydrolase, TatD family'
MVOL_RS05690	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MVOL_RS05695	COG0156	8-amino-7-oxononanoate synthase activity
MVOL_RS05730	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MVOL_RS05735	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MVOL_RS05740	COG0010	Belongs to the arginase family
MVOL_RS05750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MVOL_RS05760	COG2264	protein methyltransferase activity
MVOL_RS05830	COG0569	domain protein
MVOL_RS05835	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MVOL_RS05840	COG0505	Belongs to the CarA family
MVOL_RS05845	COG0577	efflux transmembrane transporter activity
MVOL_RS05845	COG1136	(ABC) transporter
MVOL_RS05860	COG1136	(ABC) transporter
MVOL_RS05875	COG0287	Prephenate dehydrogenase
MVOL_RS05880	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MVOL_RS05885	COG1994	Peptidase M50
MVOL_RS05890	COG3842	ATPase activity
MVOL_RS05895	COG4149	molybdate abc transporter
MVOL_RS05930	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
MVOL_RS05940	COG0167	dihydroorotate dehydrogenase activity
MVOL_RS05950	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MVOL_RS05950	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MVOL_RS05960	COG1980	fructose-bisphosphate aldolase activity
MVOL_RS05975	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MVOL_RS06085	COG3481	metal-dependent phosphohydrolase, HD sub domain
MVOL_RS06100	COG0028	Belongs to the TPP enzyme family
MVOL_RS06110	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
MVOL_RS06145	COG0425	Belongs to the sulfur carrier protein TusA family
MVOL_RS06165	COG0375	protein maturation
MVOL_RS06185	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MVOL_RS06215	COG0651	ATP synthesis coupled electron transport
MVOL_RS06220	COG1006	Multisubunit Na H antiporter MnhC subunit
MVOL_RS06225	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MVOL_RS06245	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MVOL_RS06245	COG0352	thiamine-phosphate diphosphorylase activity
MVOL_RS06245	COG0351	phosphomethylpyrimidine kinase
MVOL_RS06250	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
MVOL_RS06255	COG1160	GTP binding
MVOL_RS06275	COG0460	homoserine dehydrogenase
MVOL_RS06305	COG3259	Nickel-dependent hydrogenase
MVOL_RS06320	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MVOL_RS06325	COG0028	Belongs to the TPP enzyme family
MVOL_RS06325	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
MVOL_RS06340	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MVOL_RS06360	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MVOL_RS06375	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MVOL_RS06400	COG0175	sulfate reduction
MVOL_RS06540	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MVOL_RS06545	COG0725	ABC transporter, periplasmic molybdate-binding protein
MVOL_RS06580	COG0583	DNA-binding transcription factor activity
MVOL_RS06605	COG1098	S1 RNA binding domain
MVOL_RS06630	COG0101	tRNA pseudouridine synthase activity
MVOL_RS06635	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
MVOL_RS06650	COG1136	(ABC) transporter
MVOL_RS06655	COG1809	phosphosulfolactate synthase activity
MVOL_RS06665	COG0076	glutamate decarboxylase activity
MVOL_RS06675	COG0516	GMP reductase activity
MVOL_RS06675	COG0517	IMP dehydrogenase activity
MVOL_RS06685	COG2095	MarC family integral membrane protein
MVOL_RS06695	COG0517	IMP dehydrogenase activity
MVOL_RS06695	COG0516	GMP reductase activity
MVOL_RS06730	COG0409	Hydrogenase expression formation protein
MVOL_RS06775	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MVOL_RS06780	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MVOL_RS06785	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MVOL_RS06790	COG0303	'Molybdopterin
MVOL_RS06805	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MVOL_RS06810	COG0105	UTP biosynthetic process
MVOL_RS06815	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MVOL_RS06820	COG4956	integral membrane protein (PIN domain superfamily)
MVOL_RS06825	COG0083	homoserine kinase activity
MVOL_RS06860	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MVOL_RS06885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MVOL_RS06905	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MVOL_RS06910	COG0516	GMP reductase activity
MVOL_RS06910	COG0517	IMP dehydrogenase activity
MVOL_RS06915	COG0140	phosphoribosyl-ATP diphosphatase activity
MVOL_RS06920	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MVOL_RS06925	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MVOL_RS06935	COG1032	radical SAM domain protein
MVOL_RS06955	COG1304	FMN binding
MVOL_RS06995	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MVOL_RS07000	COG1469	GTP cyclohydrolase I activity
MVOL_RS07025	COG1797	cobyrinic acid a,c-diamide synthase activity
MVOL_RS07035	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MVOL_RS07035	COG0674	pyruvate-flavodoxin oxidoreductase activity
MVOL_RS07095	COG0864	Transcriptional regulator
MVOL_RS07105	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MVOL_RS07120	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MVOL_RS07150	COG0165	Argininosuccinate lyase
MVOL_RS07155	COG0585	pseudouridine synthase activity
MVOL_RS07160	COG1465	3-dehydroquinate synthase
MVOL_RS07205	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MVOL_RS07250	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MVOL_RS07260	COG0438	transferase activity, transferring glycosyl groups
MVOL_RS07285	COG1379	DNA repair
MVOL_RS07290	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MVOL_RS07295	COG0475	glutathione-regulated potassium exporter activity
MVOL_RS07305	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MVOL_RS07355	COG1078	dGTPase activity
MVOL_RS07360	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MVOL_RS07365	COG0569	domain protein
MVOL_RS07365	COG0189	ligase activity
MVOL_RS07375	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MVOL_RS07380	COG2217	Heavy metal translocating P-type atpase
MVOL_RS07385	COG0640	Transcriptional regulator
MVOL_RS07390	COG1227	inorganic diphosphatase activity
MVOL_RS07395	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MVOL_RS07410	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MVOL_RS07420	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MVOL_RS07430	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
MVOL_RS07435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MVOL_RS07455	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MVOL_RS07470	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MVOL_RS07475	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MVOL_RS07475	COG0519	Catalyzes the synthesis of GMP from XMP
MVOL_RS07485	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MVOL_RS07490	COG0640	Transcriptional regulator
MVOL_RS07505	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
MVOL_RS07530	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MVOL_RS07545	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MVOL_RS07555	COG3290	protein histidine kinase activity
MVOL_RS07555	COG0840	transmembrane signaling receptor activity
MVOL_RS07565	COG0513	Belongs to the DEAD box helicase family
MVOL_RS07575	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
MVOL_RS07585	COG2151	metal-sulfur cluster biosynthetic enzyme
MVOL_RS07590	COG0124	histidyl-tRNA synthetase
MVOL_RS07610	COG0017	Asparaginyl-tRNA synthetase
MVOL_RS07620	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MVOL_RS07640	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MVOL_RS07640	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MVOL_RS07655	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MVOL_RS07800	COG4974	Belongs to the 'phage' integrase family
MVOL_RS07820	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
MVOL_RS07840	COG0003	Pfam Anion-transporting ATPase
MVOL_RS07865	COG0423	glycine-tRNA ligase activity
MVOL_RS07875	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MVOL_RS07885	COG0116	Belongs to the methyltransferase superfamily
MVOL_RS07900	COG0471	metal ion transport
MVOL_RS07900	COG0490	domain, Protein
MVOL_RS07915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MVOL_RS07940	COG5012	cobalamin binding
MVOL_RS07945	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MVOL_RS07950	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MVOL_RS07955	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MVOL_RS07970	COG2271	Major facilitator Superfamily
MVOL_RS08070	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MVOL_RS08075	COG0649	NAD binding
MVOL_RS08105	COG1863	multisubunit Na H antiporter MnhE subunit
MVOL_RS08115	COG0402	S-adenosylhomocysteine deaminase activity
MVOL_RS08120	COG0529	Catalyzes the synthesis of activated sulfate
MVOL_RS08125	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MVOL_RS08130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MVOL_RS08135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MVOL_RS08140	COG1120	ATPase activity
MVOL_RS08150	COG0312	modulator of DNA gyrase
MVOL_RS08155	COG1012	belongs to the aldehyde dehydrogenase family
MVOL_RS08160	COG0521	Mo-molybdopterin cofactor biosynthetic process
MVOL_RS08175	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
MVOL_RS08180	COG0310	cobalt ion transport
MVOL_RS08185	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MVOL_RS08195	COG1797	cobyrinic acid a,c-diamide synthase activity
MVOL_RS08225	COG2255	four-way junction helicase activity
MVOL_RS08240	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MVOL_RS08245	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MVOL_RS08250	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MVOL_RS08255	COG0517	IMP dehydrogenase activity
MVOL_RS08255	COG0516	GMP reductase activity
MVOL_RS08260	COG0733	neurotransmitter:sodium symporter activity
MVOL_RS08265	COG0517	IMP dehydrogenase activity
MVOL_RS08265	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MVOL_RS08275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MVOL_RS08285	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MVOL_RS08300	COG0537	adenosine 5'-monophosphoramidase activity
MVOL_RS08305	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MVOL_RS08315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MVOL_RS08360	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MVOL_RS08365	COG0148	phosphopyruvate hydratase activity
MVOL_RS08385	COG0151	Belongs to the GarS family
MVOL_RS08390	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MVOL_RS08395	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MVOL_RS08440	COG1121	(ABC) transporter
MVOL_RS08475	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
MVOL_RS08510	COG0528	UMP kinase activity
MVOL_RS08525	COG0644	oxidoreductase
MVOL_RS08540	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MVOL_RS08595	COG0668	transmembrane transport
MVOL_RS08625	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MVOL_RS08630	COG0129	dihydroxy-acid dehydratase activity
MVOL_RS08640	COG0668	transmembrane transport
MVOL_RS08670	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MVOL_RS08670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MVOL_RS08685	COG0439	Biotin carboxylase
MVOL_RS08690	COG0511	ligase activity, forming carbon-carbon bonds
MVOL_RS08690	COG5016	pyruvate
MVOL_RS08710	COG1846	Transcriptional regulator
MVOL_RS08735	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MVOL_RS08755	COG1401	restriction endodeoxyribonuclease activity
MVOL_RS08755	COG1401	restriction endodeoxyribonuclease activity
MVOL_RS08810	COG3842	ATPase activity
MVOL_RS08955	COG0066	3-isopropylmalate dehydratase activity