locus-tag	class	description
FVF72_RS00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
FVF72_RS00045	ENOG4105DZR	Type I site-specific deoxyribonuclease
FVF72_RS00055	ENOG4105EKX	Restriction modification system DNA (Specificity
FVF72_RS00060	ENOG4105CVR	type I restriction-modification system
FVF72_RS00115	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
FVF72_RS00145	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
FVF72_RS00170	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
FVF72_RS00180	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FVF72_RS00185	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FVF72_RS00195	ENOG4105BZU	Histidine kinase
FVF72_RS00200	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
FVF72_RS00205	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
FVF72_RS00210	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
FVF72_RS00215	ENOG4108KXV	response regulator
FVF72_RS00220	ENOG4105EHU	Circadian clock protein KaiC
FVF72_RS00230	ENOG4105CN9	Peptidase m42 family protein
FVF72_RS00315	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
FVF72_RS00320	ENOG4105E3H	phosphoglycerate mutase
FVF72_RS00325	ENOG4105D6E	homoserine dehydrogenase
FVF72_RS00360	ENOG4105CJW	magnesium transporter
FVF72_RS00370	ENOG4105EDK	PfkB domain protein
FVF72_RS00375	ENOG4105FIE	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) (By similarity)
FVF72_RS00395	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FVF72_RS00400	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
FVF72_RS00495	ENOG4105FF5	Membrane
FVF72_RS00500	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
FVF72_RS00510	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
FVF72_RS00515	ENOG4105CKK	Glycosyl transferase, family 2
FVF72_RS00540	ENOG4105CPK	Glycosyl transferase (Group 1
FVF72_RS00550	ENOG4105RAK	Histidine kinase
FVF72_RS00570	ENOG4105RAK	Histidine kinase
FVF72_RS00605	ENOG4105CTK	cobaltochelatase, cobn subunit
FVF72_RS00630	ENOG4105ER6	polysaccharide biosynthesis protein
FVF72_RS00635	ENOG4105C6N	Formate acetyltransferase
FVF72_RS00640	ENOG4105F1A	Pyruvate formate-lyase
FVF72_RS00650	ENOG4107YYJ	Glycosyl transferase, family 2
FVF72_RS00660	ENOG4105D9R	oxidoreductase
FVF72_RS00680	ENOG4105CPK	Glycosyl transferase (Group 1
FVF72_RS00685	ENOG4105CPK	Glycosyl transferase (Group 1
FVF72_RS00755	ENOG4105UQX	Mate efflux family protein
FVF72_RS00770	ENOG4107QRT	dEAD DEAH box helicase
FVF72_RS00840	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
FVF72_RS00855	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FVF72_RS00880	ENOG4105MRR	Transcriptional regulator (By similarity)
FVF72_RS00935	ENOG4108V1U	phospholipid-binding protein
FVF72_RS00955	ENOG4105CH7	arginosuccinase
FVF72_RS00980	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
FVF72_RS00985	ENOG4105F0N	pyrophosphate phospho-hydrolase
FVF72_RS00995	ENOG4105EM7	Selenocysteine-specific translation elongation factor
FVF72_RS01005	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
FVF72_RS01010	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
FVF72_RS01035	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
FVF72_RS01055	ENOG41080HJ	6-phospho 3-hexuloisomerase
FVF72_RS01075	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
FVF72_RS01080	ENOG4105CUT	histidyl-tRNA synthetase
FVF72_RS01085	ENOG4108T9Q	UPF0278 protein
FVF72_RS01090	ENOG4105E2X	shikimate dehydrogenase
FVF72_RS01095	ENOG4105C6E	dna polymerase iii
FVF72_RS01100	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
FVF72_RS01115	ENOG4107T5V	SNARE associated Golgi
FVF72_RS01130	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
FVF72_RS01140	ENOG4105F8V	Hydrolase, tatD family
FVF72_RS01145	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
FVF72_RS01165	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
FVF72_RS01170	ENOG41081F0	Precorrin-8x methylmutase
FVF72_RS01175	ENOG4105C5S	asparaginyl-tRNA synthetase
FVF72_RS01180	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
FVF72_RS01200	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
FVF72_RS01205	ENOG4105CNW	domain protein
FVF72_RS01220	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FVF72_RS01225	ENOG4106HK8	GPR1 FUN34 yaaH family protein
FVF72_RS01235	ENOG4105CE1	Ferrous iron transport protein b
FVF72_RS01240	ENOG4105CGK	Exodeoxyribonuclease III
FVF72_RS01255	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FVF72_RS01270	ENOG4105C45	hydrogenase expression formation protein (HypE)
FVF72_RS01280	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
FVF72_RS01285	ENOG4105C1J	atp-dependent rna helicase
FVF72_RS01295	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
FVF72_RS01310	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FVF72_RS01315	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FVF72_RS01320	ENOG4105CBC	glutamate synthase
FVF72_RS01335	ENOG4105EYU	Glutamine amido-transferase
FVF72_RS01340	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
FVF72_RS01345	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
FVF72_RS01360	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
FVF72_RS01365	ENOG4105CAS	nag kinase
FVF72_RS01370	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
FVF72_RS01400	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
FVF72_RS01405	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
FVF72_RS01415	ENOG4105CPK	Glycosyl transferase (Group 1
FVF72_RS01420	ENOG4105E2K	Glycosyl transferase (Group 1
FVF72_RS01435	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
FVF72_RS01440	ENOG4105C8V	SAICAR synthetase
FVF72_RS01450	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
FVF72_RS01455	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
FVF72_RS01485	ENOG4105DZS	Phenylacetate-CoA ligase
FVF72_RS01495	ENOG4105D3R	alkyl hydroperoxide reductase
FVF72_RS01505	ENOG4105CNW	domain protein
FVF72_RS01510	ENOG4105VCQ	rubredoxin
FVF72_RS01515	ENOG4105VCQ	rubredoxin
FVF72_RS01540	ENOG41080TK	Universal stress protein
FVF72_RS01550	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
FVF72_RS01565	ENOG4105DCI	Phosphohydrolase
FVF72_RS01570	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
FVF72_RS01575	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
FVF72_RS01590	ENOG41082CS	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
FVF72_RS01595	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FVF72_RS01605	ENOG4107QR9	Iron-sulfur cluster binding protein
FVF72_RS01615	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
FVF72_RS01640	ENOG4108JJB	ABC transporter
FVF72_RS01655	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
FVF72_RS01660	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
FVF72_RS01670	ENOG4105E0R	Deoxyhypusine synthase
FVF72_RS01690	ENOG4105RAK	Histidine kinase
FVF72_RS01695	ENOG4108RJ7	Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP) (By similarity)
FVF72_RS01705	ENOG4108RCM	Nitroreductase
FVF72_RS01710	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
FVF72_RS01735	ENOG4105C4X	radical SAM domain protein
FVF72_RS01770	ENOG4105CBC	glutamate synthase
FVF72_RS01780	ENOG4107RDT	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
FVF72_RS01800	ENOG4105F1A	Pyruvate formate-lyase
FVF72_RS01830	ENOG4105CHM	Aminotransferase
FVF72_RS01845	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FVF72_RS01850	ENOG4105EAH	synthase
FVF72_RS01860	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
FVF72_RS01870	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
FVF72_RS01875	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
FVF72_RS01880	ENOG4105CE9	30S ribosomal protein S2
FVF72_RS01885	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
FVF72_RS01905	ENOG4108UJD	30S ribosomal protein S9
FVF72_RS01910	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
FVF72_RS01915	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
FVF72_RS01925	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
FVF72_RS01930	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
FVF72_RS01935	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FVF72_RS01945	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
FVF72_RS01980	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
FVF72_RS01990	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
FVF72_RS02010	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
FVF72_RS02015	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
FVF72_RS02040	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
FVF72_RS02045	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
FVF72_RS02055	ENOG4108ZJT	translation initiation factor, Sui1
FVF72_RS02060	ENOG41082SA	50s ribosomal protein l29
FVF72_RS02065	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
FVF72_RS02070	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
FVF72_RS02075	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
FVF72_RS02080	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FVF72_RS02085	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
FVF72_RS02090	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
FVF72_RS02095	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
FVF72_RS02105	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
FVF72_RS02110	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FVF72_RS02115	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
FVF72_RS02120	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
FVF72_RS02175	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
FVF72_RS02180	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
FVF72_RS02210	ENOG4107ZAZ	Oligosaccharyl transferase, STT3 subunit
FVF72_RS02220	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
FVF72_RS02230	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FVF72_RS02235	ENOG4105CHM	Aminotransferase
FVF72_RS02240	ENOG41076HS	cation diffusion facilitator family transporter
FVF72_RS02280	ENOG4105CJ3	phosphate transporter
FVF72_RS02285	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FVF72_RS02310	ENOG41086B8	CoB-CoM heterodisulfide reductase
FVF72_RS02345	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
FVF72_RS02350	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
FVF72_RS02360	ENOG4105CIZ	coA-substrate-specific enzyme activase
FVF72_RS02400	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
FVF72_RS02405	ENOG4107YIW	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
FVF72_RS02415	ENOG4105WR5	sporulation protein, YlmC YmxH family
FVF72_RS02420	ENOG4105ECB	domain protein
FVF72_RS02430	ENOG4105CK7	Sodium proline symporter
FVF72_RS02435	ENOG4105DZS	Phenylacetate-CoA ligase
FVF72_RS02455	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
FVF72_RS02470	ENOG4105DHP	deoxycytidine triphosphate deaminase
FVF72_RS02495	ENOG4107UEK	pfkb domain protein
FVF72_RS02545	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
FVF72_RS02550	ENOG4105D64	Mechanosensitive ion channel
FVF72_RS02565	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
FVF72_RS02570	ENOG41076CZ	activating enzyme
FVF72_RS02595	ENOG4105DWV	Homoserine O-trans-acetylase
FVF72_RS02600	ENOG410688J	Ferredoxin
FVF72_RS02615	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
FVF72_RS02630	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FVF72_RS02635	ENOG4105C0H	protease
FVF72_RS02665	ENOG4105EWK	phytoene
FVF72_RS02685	ENOG4107QRT	dEAD DEAH box helicase
FVF72_RS02700	ENOG4108R96	Methyltransferase, YaeB family
FVF72_RS02705	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
FVF72_RS02725	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
FVF72_RS02735	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
FVF72_RS02750	ENOG4105MKU	Transcriptional regulator
FVF72_RS02755	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FVF72_RS02785	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
FVF72_RS02830	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
FVF72_RS02840	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
FVF72_RS02850	ENOG4105CFP	Peptidase U32
FVF72_RS02855	ENOG4105C98	muts2 protein
FVF72_RS02875	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
FVF72_RS02910	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
FVF72_RS02920	ENOG4105CDE	UPF0348 protein
FVF72_RS02955	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
FVF72_RS02960	ENOG4105FIK	Inherit from COG: dihydropteroate synthase
FVF72_RS02965	ENOG4105EJ5	oxidoreductase gamma subunit
FVF72_RS02975	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
FVF72_RS02980	ENOG4105DDK	oxidoreductase, beta subunit
FVF72_RS02985	ENOG4108RC0	Electron transport protein
FVF72_RS03005	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
FVF72_RS03015	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
FVF72_RS03020	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FVF72_RS03025	ENOG4105C8U	phosphate abc transporter
FVF72_RS03030	ENOG4105C8U	phosphate abc transporter
FVF72_RS03035	ENOG4105CVA	phosphate
FVF72_RS03040	ENOG4105CVA	phosphate
FVF72_RS03085	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
FVF72_RS03095	ENOG4105BZ8	glutamate synthase
FVF72_RS03100	ENOG4105EYX	Acetyl-CoA decarbonylase synthase complex subunit gamma
FVF72_RS03110	ENOG41080XS	Cobyrinic acid ac-diamide synthase
FVF72_RS03115	ENOG4105E8X	CO dehydrogenase acetyl-CoA synthase complex beta subunit
FVF72_RS03130	ENOG4105G01	cobalamin (vitamin B12) biosynthesis CbiM protein
FVF72_RS03145	ENOG4108JJB	ABC transporter
FVF72_RS03180	ENOG4105CAS	nag kinase
FVF72_RS03195	ENOG4108JJB	ABC transporter
FVF72_RS03200	ENOG4105CHM	Aminotransferase
FVF72_RS03210	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
FVF72_RS03225	ENOG41080JC	Protein of unknown function DUF47
FVF72_RS03235	ENOG4107NFR	Fructose-1,6-bisphosphatase
FVF72_RS03240	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
FVF72_RS03250	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
FVF72_RS03265	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
FVF72_RS03270	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
FVF72_RS03275	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
FVF72_RS03285	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
FVF72_RS03310	ENOG4108R3D	Electron transport complex
FVF72_RS03330	ENOG4105CBC	glutamate synthase
FVF72_RS03340	ENOG4105VG1	fes assembly suf system protein
FVF72_RS03355	ENOG4107QYG	anthranilate phosphoribosyltransferase
FVF72_RS03360	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
FVF72_RS03365	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FVF72_RS03370	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
FVF72_RS03375	ENOG4105DK0	Indole-3-glycerol phosphate synthase
FVF72_RS03385	ENOG4105CRQ	synthase (Component I)
FVF72_RS03400	ENOG4105DC8	reductase
FVF72_RS03405	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
FVF72_RS03435	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
FVF72_RS03440	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FVF72_RS03445	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
FVF72_RS03460	ENOG4105C2M	dna polymerase I
FVF72_RS03465	ENOG4105M63	4-hydroxybenzoate synthetase (chorismate lyase)
FVF72_RS03470	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FVF72_RS03475	ENOG4107SDT	Homocitrate synthase
FVF72_RS03500	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
FVF72_RS03510	ENOG4105C2X	Arabinose 5-phosphate isomerase
FVF72_RS03515	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FVF72_RS03520	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
FVF72_RS03580	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FVF72_RS03595	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
FVF72_RS03600	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FVF72_RS03605	ENOG4105C7K	acetolactate synthase
FVF72_RS03610	ENOG4105C5R	Aminotransferase
FVF72_RS03635	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
FVF72_RS03640	ENOG4108UZX	fmn reductase
FVF72_RS03660	ENOG4105E3H	phosphoglycerate mutase
FVF72_RS03665	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
FVF72_RS03670	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
FVF72_RS03675	ENOG4108Z0R	Transferase
FVF72_RS03680	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FVF72_RS03685	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FVF72_RS03705	ENOG4108V2W	Carbonate dehydratase
FVF72_RS03715	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
FVF72_RS03735	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
FVF72_RS03760	ENOG4105CUZ	uba thif-type nad fad binding protein
FVF72_RS03765	ENOG4105C5F	glutamine synthetase
FVF72_RS03780	ENOG4108J2R	molybdopterin oxidoreductase
FVF72_RS03790	ENOG4105CY9	nitrogenase molybdenum-iron protein beta chain
FVF72_RS03800	ENOG4107X19	Nitrogenase component 1 type Oxidoreductase
FVF72_RS03805	ENOG4105D0B	Nitrogenase protein alpha chain
FVF72_RS03810	ENOG4108YZA	Nitrogen regulatory protein pii
FVF72_RS03815	ENOG4108YZA	Nitrogen regulatory protein pii
FVF72_RS03820	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
FVF72_RS03825	ENOG4108JB9	formate dehydrogenase
FVF72_RS03835	ENOG4105DCC	Formylmethanofuran dehydrogenase subunit A
FVF72_RS03860	ENOG4108JB9	formate dehydrogenase
FVF72_RS03870	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FVF72_RS03875	ENOG4107QIZ	NADH dehydrogenase
FVF72_RS03885	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
FVF72_RS03890	ENOG41080HJ	6-phospho 3-hexuloisomerase
FVF72_RS03910	ENOG4105DK7	lysyl-tRNA synthetase
FVF72_RS03930	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
FVF72_RS03940	ENOG4105C83	adenylosuccinate lyase
FVF72_RS03960	ENOG4105CI2	imidazolone-5-propionate hydrolase
FVF72_RS03980	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
FVF72_RS03985	ENOG4105DZS	Phenylacetate-CoA ligase
FVF72_RS04005	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
FVF72_RS04010	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
FVF72_RS04020	ENOG4105PW4	Sugar fermentation stimulation protein homolog
FVF72_RS04035	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
FVF72_RS04040	ENOG4105C3G	gtp-binding protein
FVF72_RS04065	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
FVF72_RS04070	ENOG4105VF7	tolerance protein
FVF72_RS04080	ENOG4105ERH	Fumarylacetoacetate hydrolase
FVF72_RS04085	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
FVF72_RS04090	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
FVF72_RS04105	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
FVF72_RS04115	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
FVF72_RS04120	ENOG4105EHU	Circadian clock protein KaiC
FVF72_RS04130	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
FVF72_RS04155	ENOG4105CGH	5'-nucleotidase
FVF72_RS04185	ENOG4105CJ1	ABC, transporter
FVF72_RS04215	ENOG4105CY9	nitrogenase molybdenum-iron protein beta chain
FVF72_RS04220	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FVF72_RS04230	ENOG4105C0B	DNA polymerase III (alpha subunit)
FVF72_RS04240	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FVF72_RS04250	ENOG4108P4C	Formaldehyde-activating enzyme
FVF72_RS04270	ENOG4107SVV	electron transport complex, RnfABCDGE type, B subunit
FVF72_RS04275	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
FVF72_RS04305	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
FVF72_RS04325	ENOG4107QJE	Chromosome Partitioning Protein
FVF72_RS04330	ENOG4105C22	threonyL-tRNA synthetase
FVF72_RS04335	ENOG4108NGU	Transcriptional regulator
FVF72_RS04340	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
FVF72_RS04350	ENOG4107PU6	Membrane
FVF72_RS04355	ENOG4105C01	Dihydroxy-acid dehydratase
FVF72_RS04365	ENOG4105C75	arginyL-tRNA synthetase
FVF72_RS04370	ENOG4105DBV	ornithine carbamoyltransferase
FVF72_RS04375	ENOG4105C12	Phosphoribosylglycinamide synthetase
FVF72_RS04380	ENOG4105C7K	acetolactate synthase
FVF72_RS04385	ENOG4108ZP8	Acetolactate synthase small subunit
FVF72_RS04390	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
FVF72_RS04425	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
FVF72_RS04450	ENOG4105CM2	brancheD-chain amino acid aminotransferase
FVF72_RS04455	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
FVF72_RS04465	ENOG4108K7V	UPF0284 protein
FVF72_RS04470	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FVF72_RS04475	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
FVF72_RS04480	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
FVF72_RS04515	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
FVF72_RS04520	ENOG41066UU	tRNA (Adenine-N1-)-methyltransferase
FVF72_RS04525	ENOG4105CXT	aspartate transcarbamylase
FVF72_RS04540	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
FVF72_RS04545	ENOG4108P62	biosynthesis protein (CbiG)
FVF72_RS04555	ENOG4105FB2	class II Aldolase
FVF72_RS04570	ENOG4105E4R	Precorrin-3B C17-methyltransferase
FVF72_RS04605	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
FVF72_RS04615	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
FVF72_RS04620	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
FVF72_RS04625	ENOG4105C3Q	Glycosyl transferase, family 2
FVF72_RS04635	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
FVF72_RS04645	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
FVF72_RS04650	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FVF72_RS04655	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FVF72_RS04675	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
FVF72_RS04680	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
FVF72_RS04700	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
FVF72_RS04705	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
FVF72_RS04710	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
FVF72_RS04730	ENOG4105CJ1	ABC, transporter
FVF72_RS04760	ENOG4105CE1	Ferrous iron transport protein b
FVF72_RS04775	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
FVF72_RS04790	ENOG4108UXE	Protein tyrosine phosphatase
FVF72_RS04805	ENOG4105VCQ	rubredoxin
FVF72_RS04810	ENOG4105KY8	Rubrerythrin
FVF72_RS04815	ENOG4105CNW	domain protein
FVF72_RS04825	ENOG4105DVK	Precorrin-2 c20-methyltransferase
FVF72_RS04885	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
FVF72_RS04905	ENOG4108ZCU	PPIases accelerate the folding of proteins
FVF72_RS04910	ENOG4105C8Y	Acetylornithine aminotransferase
FVF72_RS04920	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
FVF72_RS04930	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
FVF72_RS04935	ENOG4105VZ8	Transcriptional regulator
FVF72_RS04945	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
FVF72_RS04950	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
FVF72_RS04970	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FVF72_RS04975	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
FVF72_RS05035	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
FVF72_RS05080	ENOG4108USZ	hydrogenase
FVF72_RS05085	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FVF72_RS05095	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
FVF72_RS05130	ENOG4105CFG	Acts as a chaperone (By similarity)
FVF72_RS05135	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FVF72_RS05150	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
FVF72_RS05155	ENOG4105KVH	Transcriptional regulator
FVF72_RS05165	ENOG41083RF	phosphoribosyl-ATP pyrophosphatase
FVF72_RS05170	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FVF72_RS05180	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FVF72_RS05240	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
FVF72_RS05250	ENOG4105C1A	potassium transporter peripheral membrane
FVF72_RS05260	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
FVF72_RS05280	ENOG4105FIE	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) (By similarity)
FVF72_RS05285	ENOG4107PBV	potassium channel
FVF72_RS05290	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
FVF72_RS05315	ENOG4105SC1	monovalent cation H antiporter subunit E
FVF72_RS05380	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FVF72_RS05385	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
FVF72_RS05445	ENOG4107WPW	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
FVF72_RS05450	ENOG41080XP	Cbs domain
FVF72_RS05455	ENOG4105W87	Cbs domain
FVF72_RS05460	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FVF72_RS05465	ENOG41080XP	Cbs domain
FVF72_RS05480	ENOG4105CQC	Prephenate dehydratase
FVF72_RS05500	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
FVF72_RS05515	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
FVF72_RS05520	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
FVF72_RS05525	ENOG4105C02	permease
FVF72_RS05585	ENOG4105DTI	Phosphonopyruvate decarboxylase
FVF72_RS05595	ENOG4105DG4	malate L-lactate dehydrogenase
FVF72_RS05600	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
FVF72_RS05605	ENOG4105CY0	Metallo-Beta-Lactamase
FVF72_RS05630	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
FVF72_RS05640	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
FVF72_RS05650	ENOG4105DGU	Histone deacetylase
FVF72_RS05670	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
FVF72_RS05675	ENOG4107FCW	Abortive infection protein
FVF72_RS05680	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
FVF72_RS05690	ENOG4107R56	PP-loop domain protein
FVF72_RS05695	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FVF72_RS05710	ENOG4108N5B	2-phosphosulfolactate phosphatase
FVF72_RS05725	ENOG4107RN3	metallophosphoesterase
FVF72_RS05730	ENOG4105VYW	UPF0251 protein
FVF72_RS05735	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FVF72_RS05805	ENOG4108QZ0	Tetrahydromethanopterin S-methyltransferase (EC 2.1.1.86)
FVF72_RS05810	ENOG4105FEU	K -dependent Na -Ca exchanger
FVF72_RS05825	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
FVF72_RS05870	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
FVF72_RS05950	ENOG4105CD3	dihydroorotase
FVF72_RS05955	ENOG4105CDE	UPF0348 protein
FVF72_RS05960	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
FVF72_RS05965	ENOG4105RAK	Histidine kinase
FVF72_RS05975	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
FVF72_RS05985	ENOG41080XS	Cobyrinic acid ac-diamide synthase
FVF72_RS05990	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
FVF72_RS06000	ENOG4105DY8	decarboxylase
FVF72_RS06010	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
FVF72_RS06020	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
FVF72_RS06035	ENOG4105C8M	UPF0272 protein
FVF72_RS06040	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
FVF72_RS06045	ENOG4107QSA	Oxaloacetate decarboxylase
FVF72_RS06050	ENOG4105Z5G	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FVF72_RS06055	ENOG4105CZA	synthase
FVF72_RS06080	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
FVF72_RS06170	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
FVF72_RS06175	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
FVF72_RS06190	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
FVF72_RS06200	ENOG4105G15	CRISPR-associated RAMP protein, Csm5 family
FVF72_RS06225	ENOG4105FEU	K -dependent Na -Ca exchanger
FVF72_RS06250	ENOG4105Q33	Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency
FVF72_RS06255	ENOG4107STF	Involved in phosphonate degradation (By similarity)
FVF72_RS06265	ENOG41068KF	Universal stress protein
FVF72_RS06295	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
FVF72_RS06300	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FVF72_RS06305	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FVF72_RS06310	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
FVF72_RS06320	ENOG4105CHV	Transcription elongation factor NusA
FVF72_RS06330	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FVF72_RS06335	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FVF72_RS06340	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FVF72_RS06345	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FVF72_RS06380	ENOG4105BZA	Phosphoglycerate kinase
FVF72_RS06430	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
FVF72_RS06440	ENOG4105DQU	oxidoreductase, subunit beta
FVF72_RS06445	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
FVF72_RS06475	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
FVF72_RS06480	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
FVF72_RS06490	ENOG4105DFF	Rod shape-determining protein mreb
FVF72_RS06520	ENOG4105EIH	LPPG Fo 2-phospho-L-lactate transferase
FVF72_RS06535	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
FVF72_RS06555	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FVF72_RS06615	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
FVF72_RS06620	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
FVF72_RS06635	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
FVF72_RS06640	ENOG4107YZX	Universal stress protein
FVF72_RS06645	ENOG41080XP	Cbs domain
FVF72_RS06675	ENOG4105RAK	Histidine kinase
FVF72_RS06690	ENOG4105DC7	peptidase M24
FVF72_RS06715	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FVF72_RS06730	ENOG4108Q27	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity)
FVF72_RS06770	ENOG4108PGP	mmge prpd family protein
FVF72_RS06800	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FVF72_RS06820	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
FVF72_RS06825	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
FVF72_RS06830	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
FVF72_RS06875	ENOG4108MYP	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
FVF72_RS06890	ENOG4105DZR	Type I site-specific deoxyribonuclease
FVF72_RS06970	ENOG4107XNE	ABC transporter, periplasmic molybdate-binding protein
FVF72_RS06985	ENOG4105F38	ABC transporter, permease
FVF72_RS06990	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FVF72_RS07035	ENOG4107ZYJ	bioY protein
FVF72_RS07065	ENOG4107YZX	Universal stress protein
FVF72_RS07085	ENOG4107S21	permease
FVF72_RS07090	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FVF72_RS07095	ENOG4105C0P	Mg chelatase subunit ChlI
FVF72_RS07115	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
FVF72_RS07160	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
FVF72_RS07175	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
FVF72_RS07185	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
FVF72_RS07190	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
FVF72_RS07195	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
FVF72_RS07215	ENOG4105CYW	agmatinase
FVF72_RS07225	ENOG4105CPN	adenine deaminase
FVF72_RS07245	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
FVF72_RS07250	ENOG4107Y70	Heat shock protein
FVF72_RS07255	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
FVF72_RS07260	ENOG4105NBF	ammecr1 domain protein
FVF72_RS07270	ENOG4105CJW	magnesium transporter
FVF72_RS07275	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
FVF72_RS07295	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
FVF72_RS07300	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FVF72_RS07315	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
FVF72_RS07325	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
FVF72_RS07330	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
FVF72_RS07345	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
FVF72_RS07355	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
FVF72_RS07365	ENOG4105C12	Phosphoribosylglycinamide synthetase
FVF72_RS07385	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FVF72_RS07395	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FVF72_RS07405	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
FVF72_RS07410	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FVF72_RS07430	ENOG4105RAK	Histidine kinase
FVF72_RS07435	ENOG4108RAC	Rubrerythrin
FVF72_RS07445	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
FVF72_RS07455	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
FVF72_RS07500	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FVF72_RS07505	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
FVF72_RS07515	ENOG4105D07	Signal peptide peptidase, SppA
FVF72_RS07520	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
FVF72_RS07525	ENOG4105CQC	Prephenate dehydratase
FVF72_RS07540	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FVF72_RS07545	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
FVF72_RS07550	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
FVF72_RS07555	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
FVF72_RS07565	ENOG4106IPI	cyclase, family
FVF72_RS07575	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
FVF72_RS07580	ENOG4105CHU	acetyl-coa acetyltransferase
FVF72_RS07605	ENOG4105C8P	)-transporter
FVF72_RS07615	ENOG4105BZU	Histidine kinase
FVF72_RS07620	ENOG4108IUQ	atp-dependent protease
FVF72_RS07625	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FVF72_RS07630	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
FVF72_RS07650	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
FVF72_RS07670	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
FVF72_RS07675	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
FVF72_RS07680	ENOG41068T5	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT (By similarity)
FVF72_RS07695	ENOG4107TIA	phenylalanyl-tRNA synthetase (beta subunit)
FVF72_RS07715	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
FVF72_RS07720	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
FVF72_RS07725	ENOG4105CSM	endonuclease III
FVF72_RS07730	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
FVF72_RS07765	ENOG4105MAX	Superoxide reductase
FVF72_RS07780	ENOG4105C7Z	Conserved Protein
FVF72_RS07805	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
FVF72_RS07825	ENOG4105D52	delta-aminolevulinic acid dehydratase
FVF72_RS07835	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
FVF72_RS07850	ENOG4105MRR	Transcriptional regulator (By similarity)
FVF72_RS07860	ENOG4108MG9	hydrogenase 3 maturation protease
FVF72_RS07865	ENOG4105CPF	Cell wall formation (By similarity)
FVF72_RS07870	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
FVF72_RS07875	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
FVF72_RS07900	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FVF72_RS07915	ENOG4105P52	geranylgeranyl reductase
FVF72_RS07920	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
FVF72_RS07925	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FVF72_RS07990	ENOG4105E0X	reductase
FVF72_RS07995	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FVF72_RS08000	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FVF72_RS08005	ENOG4106H3A	restriction
FVF72_RS08010	ENOG4105C3M	thioredoxin reductase
FVF72_RS08015	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FVF72_RS08015	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FVF72_RS08020	ENOG4105HDK	L-asparaginase
FVF72_RS08030	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
FVF72_RS08040	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FVF72_RS08065	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FVF72_RS08070	ENOG4107RBB	ABC transporter, permease
FVF72_RS08140	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
FVF72_RS08150	ENOG4108FK2	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
FVF72_RS08200	ENOG4105CTK	cobaltochelatase, cobn subunit
FVF72_RS08235	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
FVF72_RS08245	ENOG4108YZA	Nitrogen regulatory protein pii
FVF72_RS08250	ENOG4105BZU	Histidine kinase
FVF72_RS08255	ENOG4108YZA	Nitrogen regulatory protein pii
FVF72_RS08260	ENOG4105BZU	Histidine kinase
FVF72_RS08280	ENOG4105CEY	Amp-dependent synthetase and ligase
FVF72_RS08285	ENOG4105CQR	helicase
FVF72_RS08305	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FVF72_RS08340	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
FVF72_RS08345	ENOG4105CFP	Peptidase U32
FVF72_RS08350	ENOG41080XP	Cbs domain
FVF72_RS08380	ENOG4105VZ9	UPF0235 protein
FVF72_RS08395	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
FVF72_RS08410	ENOG4105CMR	udp-glucose 4-epimerase
FVF72_RS08450	ENOG4105KHC	sulfurtransferase
FVF72_RS08460	ENOG4105CJW	magnesium transporter
FVF72_RS08465	ENOG4105BZU	Histidine kinase
FVF72_RS08490	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
FVF72_RS08495	ENOG4105DWF	phosphomethylpyrimidine kinase
FVF72_RS08510	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
FVF72_RS08515	ENOG4107SCQ	Iron-containing alcohol dehydrogenase
FVF72_RS08525	ENOG4105E66	phosphoriboisomerase A
FVF72_RS08540	ENOG4105DIK	(ABC) transporter
FVF72_RS08545	ENOG4105DSE	periplasmic solute binding protein
FVF72_RS08555	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
FVF72_RS08595	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
FVF72_RS08615	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
FVF72_RS08630	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
FVF72_RS08650	ENOG4105M7V	2'-5' rna ligase
FVF72_RS08660	ENOG4106M32	3-dehydroquinate synthase
FVF72_RS08665	ENOG41061GT	Aldolase
FVF72_RS08670	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
FVF72_RS08680	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
FVF72_RS08690	ENOG4105D0M	Protease HtpX homolog
FVF72_RS08700	ENOG4105FF2	Type I DHQase
FVF72_RS08710	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
FVF72_RS08745	ENOG4105EET	magnesium chelatase
FVF72_RS08760	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
FVF72_RS08765	ENOG4105DCG	PHP domain protein
FVF72_RS08770	ENOG4107R8N	Glycosyl transferase, family 2
FVF72_RS08780	ENOG4105CUB	amino acid
FVF72_RS08790	ENOG41083I7	UPF0145 protein
FVF72_RS08810	ENOG4105EYH	Exonuclease
FVF72_RS08825	ENOG4105DQU	oxidoreductase, subunit beta
FVF72_RS08835	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
FVF72_RS08850	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
FVF72_RS08855	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
FVF72_RS08865	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
FVF72_RS08925	ENOG4105CTK	cobaltochelatase, cobn subunit
FVF72_RS08955	ENOG4105K8R	UPF0145 protein
FVF72_RS08960	ENOG4105K8R	UPF0145 protein
FVF72_RS08990	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
FVF72_RS09020	ENOG4108I5C	dEAD DEAH box helicase
FVF72_RS09120	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FVF72_RS09145	ENOG4105DZR	Type I site-specific deoxyribonuclease
FVF72_RS09155	ENOG4105EKX	Restriction modification system DNA (Specificity
FVF72_RS09160	ENOG4105CVR	type I restriction-modification system