locus-tag	class	description
MINF_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MINF_RS00010	COG0592	DNA-directed DNA polymerase activity
MINF_RS00020	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MINF_RS00025	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MINF_RS00030	COG1458	PINc domain ribonuclease
MINF_RS00040	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MINF_RS00045	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MINF_RS00055	COG4589	Belongs to the CDS family
MINF_RS00060	COG0688	phosphatidylethanolamine metabolic process
MINF_RS00065	COG1183	phosphatidylcholine synthase activity
MINF_RS00075	COG1509	lysine 2,3-aminomutase activity
MINF_RS00085	COG0574	Belongs to the PEP-utilizing enzyme family
MINF_RS00085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MINF_RS00090	COG0045	succinate-CoA ligase (ADP-forming) activity
MINF_RS00090	COG1042	CoA-binding domain protein
MINF_RS00090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MINF_RS00100	COG1475	DNA binding
MINF_RS00110	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MINF_RS00115	COG0012	GTP binding
MINF_RS00145	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MINF_RS00150	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MINF_RS00155	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MINF_RS00160	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MINF_RS00165	COG3360	Dodecin
MINF_RS00170	COG0590	tRNA wobble adenosine to inosine editing
MINF_RS00175	COG2010	Cytochrome c
MINF_RS00180	COG3256	nitric oxide reductase
MINF_RS00195	COG2226	methyltransferase
MINF_RS00205	COG0497	DNA recombination
MINF_RS00210	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MINF_RS00220	COG0315	cyclic pyranopterin monophosphate synthase activity
MINF_RS00225	COG0521	Mo-molybdopterin cofactor biosynthetic process
MINF_RS00235	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MINF_RS00270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MINF_RS00285	COG1469	GTP cyclohydrolase I activity
MINF_RS00300	COG0508	dehydrogenase complex catalyzes the overall conversion of
MINF_RS00305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MINF_RS00310	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MINF_RS00320	COG0802	atpase or kinase
MINF_RS00325	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MINF_RS00335	COG0616	signal peptide processing
MINF_RS00345	COG0776	regulation of translation
MINF_RS00350	COG0124	histidyl-tRNA synthetase
MINF_RS00355	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MINF_RS00365	COG0300	oxidoreductase activity
MINF_RS00380	COG0717	Belongs to the dCTP deaminase family
MINF_RS00390	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MINF_RS00415	COG4864	UPF0365 protein
MINF_RS00430	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MINF_RS00475	COG0076	glutamate decarboxylase activity
MINF_RS00480	COG0248	Ppx GppA phosphatase
MINF_RS00490	COG0542	response to heat
MINF_RS00495	COG2363	Small membrane protein
MINF_RS00500	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MINF_RS00505	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MINF_RS00510	COG3239	Fatty acid desaturase
MINF_RS00515	COG3511	phospholipase C
MINF_RS00580	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MINF_RS00585	COG0167	dihydroorotate dehydrogenase activity
MINF_RS00590	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MINF_RS00605	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MINF_RS00615	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
MINF_RS00625	COG2226	methyltransferase
MINF_RS00630	COG2226	methyltransferase
MINF_RS00680	COG1331	Highly conserved protein containing a thioredoxin domain
MINF_RS00695	COG5002	protein histidine kinase activity
MINF_RS00700	COG0745	RESPONSE REGULATOR receiver
MINF_RS00705	COG0187	DNA topoisomerase II activity
MINF_RS00710	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MINF_RS00715	COG0009	L-threonylcarbamoyladenylate synthase
MINF_RS00720	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MINF_RS00760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MINF_RS00785	COG1160	GTP binding
MINF_RS00795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MINF_RS00795	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
MINF_RS00805	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MINF_RS00810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MINF_RS00820	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MINF_RS00825	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MINF_RS00830	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MINF_RS00835	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MINF_RS00840	COG4122	O-methyltransferase activity
MINF_RS00845	COG3118	belongs to the thioredoxin family
MINF_RS00850	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MINF_RS00885	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MINF_RS00895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MINF_RS00900	COG1136	(ABC) transporter
MINF_RS00910	COG0287	Prephenate dehydrogenase
MINF_RS00915	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MINF_RS00935	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MINF_RS00945	COG0649	NAD binding
MINF_RS00950	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
MINF_RS00960	COG1034	ATP synthesis coupled electron transport
MINF_RS00965	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MINF_RS00970	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MINF_RS00990	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MINF_RS00995	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MINF_RS01000	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MINF_RS01005	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MINF_RS01010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MINF_RS01045	COG2084	Dehydrogenase
MINF_RS01055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MINF_RS01065	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MINF_RS01075	COG0542	response to heat
MINF_RS01080	COG3869	Catalyzes the specific phosphorylation of arginine residues in
MINF_RS01085	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MINF_RS01090	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MINF_RS01090	COG0519	Catalyzes the synthesis of GMP from XMP
MINF_RS01095	COG0516	GMP reductase activity
MINF_RS01115	COG0811	peptide transport
MINF_RS01125	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MINF_RS01135	COG2226	methyltransferase
MINF_RS01145	COG0058	SHG alpha-glucan phosphorylase activity
MINF_RS01150	COG0387	Pfam Sodium calcium exchanger
MINF_RS01160	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MINF_RS01170	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MINF_RS01180	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MINF_RS01200	COG0564	pseudouridine synthase activity
MINF_RS01235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MINF_RS01235	COG1199	ATP-dependent helicase activity
MINF_RS01240	COG0436	Aminotransferase
MINF_RS01245	COG0730	response to heat
MINF_RS01255	COG1692	metallophosphoesterase
MINF_RS01260	COG0724	RNA recognition motif
MINF_RS01265	COG0191	fructose-bisphosphate aldolase activity
MINF_RS01280	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MINF_RS01280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MINF_RS01285	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MINF_RS01290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MINF_RS01295	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MINF_RS01320	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MINF_RS01330	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MINF_RS01335	COG1994	Peptidase M50
MINF_RS01335	COG0517	IMP dehydrogenase activity
MINF_RS01365	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MINF_RS01375	COG0148	phosphopyruvate hydratase activity
MINF_RS01380	COG2814	Major facilitator Superfamily
MINF_RS01425	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MINF_RS01430	COG1196	nuclear chromosome segregation
MINF_RS01475	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MINF_RS01500	COG0372	Belongs to the citrate synthase family
MINF_RS01530	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MINF_RS01535	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MINF_RS01545	COG0297	glycogen (starch) synthase activity
MINF_RS01555	COG1649	PFAM Uncharacterised BCR, COG1649
MINF_RS01555	COG0726	polysaccharide deacetylase
MINF_RS01560	COG0463	Glycosyl transferase, family 2
MINF_RS01585	COG1216	Glycosyl transferase, family 2
MINF_RS01605	COG2204	response regulator
MINF_RS01615	COG0735	belongs to the Fur family
MINF_RS01630	COG0052	Belongs to the universal ribosomal protein uS2 family
MINF_RS01635	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MINF_RS01640	COG0439	Biotin carboxylase
MINF_RS01645	COG0352	thiamine-phosphate diphosphorylase activity
MINF_RS01660	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MINF_RS01665	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MINF_RS01675	COG2759	Belongs to the formate--tetrahydrofolate ligase family
MINF_RS01695	COG0481	GTPase activity
MINF_RS01700	COG0667	Aldo Keto reductase
MINF_RS01710	COG1253	flavin adenine dinucleotide binding
MINF_RS01720	COG0285	dihydrofolate synthase activity
MINF_RS01735	COG1053	succinate dehydrogenase
MINF_RS01740	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MINF_RS01750	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MINF_RS01760	COG0573	inorganic phosphate transmembrane transporter activity
MINF_RS01765	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MINF_RS01775	COG0142	geranyltranstransferase activity
MINF_RS01785	COG1657	PFAM Prenyltransferase squalene oxidase
MINF_RS01800	COG0495	leucyl-tRNA aminoacylation
MINF_RS01815	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MINF_RS01825	COG1528	Iron-storage protein
MINF_RS01835	COG1192	Involved in chromosome partitioning
MINF_RS01840	COG1131	(ABC) transporter
MINF_RS01870	COG1566	PFAM secretion protein HlyD family protein
MINF_RS01875	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MINF_RS01910	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MINF_RS01915	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MINF_RS01920	COG2890	protein-(glutamine-N5) methyltransferase activity
MINF_RS01925	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MINF_RS01930	COG0254	rRNA binding
MINF_RS01935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MINF_RS01940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MINF_RS01945	COG1028	Short-chain dehydrogenase reductase Sdr
MINF_RS01955	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MINF_RS01960	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MINF_RS01970	COG1674	ftsk spoiiie
MINF_RS01995	COG1562	ergosterol biosynthetic process
MINF_RS02000	COG0237	dephospho-CoA kinase activity
MINF_RS02025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MINF_RS02035	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MINF_RS02055	COG5554	nitrogen fixation
MINF_RS02060	COG1104	cysteine desulfurase activity
MINF_RS02070	COG2897	thiosulfate sulfurtransferase activity
MINF_RS02080	COG0316	Belongs to the HesB IscA family
MINF_RS02085	COG0316	Belongs to the HesB IscA family
MINF_RS02120	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MINF_RS02145	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MINF_RS02175	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MINF_RS02175	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MINF_RS02180	COG0316	Belongs to the HesB IscA family
MINF_RS02200	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MINF_RS02205	COG0632	four-way junction helicase activity
MINF_RS02210	COG2255	four-way junction helicase activity
MINF_RS02235	COG0438	transferase activity, transferring glycosyl groups
MINF_RS02235	COG1216	Glycosyl transferase, family 2
MINF_RS02240	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MINF_RS02250	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
MINF_RS02260	COG0579	oxidoreductase
MINF_RS02270	COG1902	pentaerythritol trinitrate reductase activity
MINF_RS02275	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MINF_RS02280	COG0651	ATP synthesis coupled electron transport
MINF_RS02285	COG0650	Formate hydrogenlyase subunit 4
MINF_RS02295	COG0651	ATP synthesis coupled electron transport
MINF_RS02300	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
MINF_RS02300	COG3261	NADH dehydrogenase
MINF_RS02305	COG3260	NADH ubiquinone oxidoreductase 20
MINF_RS02345	COG0535	radical SAM domain protein
MINF_RS02360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MINF_RS02380	COG2308	Evidence 4 Homologs of previously reported genes of
MINF_RS02395	COG1305	Transglutaminase-like
MINF_RS02410	COG4122	O-methyltransferase activity
MINF_RS02420	COG1674	ftsk spoiiie
MINF_RS02455	COG0438	transferase activity, transferring glycosyl groups
MINF_RS02490	COG0438	transferase activity, transferring glycosyl groups
MINF_RS02505	COG0500	methyltransferase
MINF_RS02525	COG0489	protein tyrosine kinase activity
MINF_RS02540	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MINF_RS02560	COG2197	response regulator
MINF_RS02570	COG0745	RESPONSE REGULATOR receiver
MINF_RS02640	COG0588	phosphoglycerate mutase activity
MINF_RS02645	COG2205	protein histidine kinase activity
MINF_RS02655	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MINF_RS02665	COG1902	pentaerythritol trinitrate reductase activity
MINF_RS02670	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MINF_RS02675	COG2079	MmgE PrpD family protein
MINF_RS02695	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MINF_RS02710	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MINF_RS02715	COG0730	response to heat
MINF_RS02765	COG0493	'glutamate synthase
MINF_RS02805	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
MINF_RS02810	COG0154	amidase activity
MINF_RS02840	COG0438	transferase activity, transferring glycosyl groups
MINF_RS02855	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MINF_RS02860	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MINF_RS02870	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MINF_RS02875	COG0217	transcriptional regulatory protein
MINF_RS02885	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MINF_RS02905	COG0058	SHG alpha-glucan phosphorylase activity
MINF_RS02935	COG0517	IMP dehydrogenase activity
MINF_RS02935	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MINF_RS02940	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MINF_RS02945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MINF_RS02950	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MINF_RS02955	COG1522	sequence-specific DNA binding
MINF_RS02960	COG0436	Aminotransferase
MINF_RS02970	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MINF_RS03000	COG0742	ribosomal rna small subunit methyltransferase
MINF_RS03010	COG1597	lipid kinase activity
MINF_RS03015	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MINF_RS03020	COG0049	tRNA binding
MINF_RS03025	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MINF_RS03030	COG0051	transcription antitermination factor activity, RNA binding
MINF_RS03035	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MINF_RS03040	COG0088	Forms part of the polypeptide exit tunnel
MINF_RS03045	COG0089	rRNA binding
MINF_RS03050	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MINF_RS03055	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MINF_RS03060	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MINF_RS03065	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MINF_RS03070	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MINF_RS03075	COG0255	Belongs to the universal ribosomal protein uL29 family
MINF_RS03080	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MINF_RS03085	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MINF_RS03090	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MINF_RS03095	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MINF_RS03100	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MINF_RS03105	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MINF_RS03110	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MINF_RS03115	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MINF_RS03120	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MINF_RS03125	COG0200	Binds to the 23S rRNA
MINF_RS03190	COG4221	oxidoreductase activity
MINF_RS03205	COG0628	permease
MINF_RS03210	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MINF_RS03220	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MINF_RS03225	COG0322	excinuclease ABC activity
MINF_RS03230	COG4232	protein-disulfide reductase activity
MINF_RS03325	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MINF_RS03330	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MINF_RS03335	COG0460	homoserine dehydrogenase
MINF_RS03340	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MINF_RS03355	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MINF_RS03360	COG0359	binds to the 23S rRNA
MINF_RS03365	COG0629	single-stranded DNA binding
MINF_RS03375	COG0193	aminoacyl-tRNA hydrolase activity
MINF_RS03380	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MINF_RS03385	COG2205	protein histidine kinase activity
MINF_RS03390	COG0745	RESPONSE REGULATOR receiver
MINF_RS03395	COG2207	Transcriptional regulator
MINF_RS03410	COG0736	holo-[acyl-carrier-protein] synthase activity
MINF_RS03415	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MINF_RS03420	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MINF_RS03425	COG3852	Histidine kinase
MINF_RS03440	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MINF_RS03485	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MINF_RS03490	COG1127	ABC transporter
MINF_RS03500	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MINF_RS03505	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MINF_RS03515	COG3876	Protein conserved in bacteria
MINF_RS03520	COG0058	SHG alpha-glucan phosphorylase activity
MINF_RS03525	COG2326	polyphosphate kinase activity
MINF_RS03530	COG0114	fumarate hydratase activity
MINF_RS03535	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MINF_RS03535	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MINF_RS03540	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MINF_RS03545	COG1570	exodeoxyribonuclease VII activity
MINF_RS03555	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MINF_RS03575	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MINF_RS03580	COG0081	regulation of translation
MINF_RS03585	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MINF_RS03590	COG0222	ribosome binding
MINF_RS03595	COG0085	RNA polymerase activity
MINF_RS03600	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MINF_RS03605	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MINF_RS03615	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MINF_RS03620	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MINF_RS03635	COG1968	undecaprenyl-diphosphatase activity
MINF_RS03640	COG1686	Belongs to the peptidase S11 family
MINF_RS03650	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MINF_RS03665	COG0463	Glycosyl transferase, family 2
MINF_RS03670	COG0563	adenylate kinase activity
MINF_RS03675	COG0811	peptide transport
MINF_RS03730	COG1074	ATP-dependent DNA helicase activity
MINF_RS03745	COG0805	protein transport
MINF_RS03750	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MINF_RS03760	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MINF_RS03775	COG0356	it plays a direct role in the translocation of protons across the membrane
MINF_RS03795	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MINF_RS03860	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MINF_RS03975	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MINF_RS03980	COG0438	transferase activity, transferring glycosyl groups
MINF_RS03990	COG2224	Isocitrate lyase
MINF_RS03995	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MINF_RS04005	COG0277	FAD linked oxidase domain protein
MINF_RS04010	COG0277	FAD linked oxidase domain protein
MINF_RS04015	COG0247	lactate metabolic process
MINF_RS04025	COG1566	PFAM secretion protein HlyD family protein
MINF_RS04035	COG2814	Major facilitator Superfamily
MINF_RS04045	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
MINF_RS04055	COG0758	DNA mediated transformation
MINF_RS04060	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MINF_RS04075	COG1137	ATPase activity
MINF_RS04095	COG0242	peptide deformylase activity
MINF_RS04100	COG0848	biopolymer transport protein
MINF_RS04105	COG0811	peptide transport
MINF_RS04130	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MINF_RS04135	COG0706	membrane insertase activity
MINF_RS04140	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MINF_RS04145	COG1733	regulation of RNA biosynthetic process
MINF_RS04175	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MINF_RS04215	COG0473	3-isopropylmalate dehydrogenase activity
MINF_RS04235	COG1640	4-alpha-glucanotransferase
MINF_RS04265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MINF_RS04290	COG2877	3-deoxy-8-phosphooctulonate synthase activity
MINF_RS04295	COG0504	CTP synthase activity
MINF_RS04300	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MINF_RS04305	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MINF_RS04310	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MINF_RS04310	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MINF_RS04330	COG2957	Belongs to the agmatine deiminase family
MINF_RS04345	COG1104	cysteine desulfurase activity
MINF_RS04350	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MINF_RS04355	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MINF_RS04370	COG0303	'Molybdopterin
MINF_RS04390	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MINF_RS04415	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MINF_RS04420	COG0725	ABC transporter, periplasmic molybdate-binding protein
MINF_RS04430	COG3842	ATPase activity
MINF_RS04470	COG2154	pterin-4-alpha-carbinolamine dehydratase
MINF_RS04485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MINF_RS04500	COG0022	dehydrogenase e1 component
MINF_RS04500	COG0508	dehydrogenase complex catalyzes the overall conversion of
MINF_RS04505	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MINF_RS04510	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MINF_RS04540	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MINF_RS04545	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MINF_RS04550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MINF_RS04555	COG0166	Belongs to the GPI family
MINF_RS04570	COG0366	Alpha amylase catalytic
MINF_RS04580	COG2204	response regulator
MINF_RS04590	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MINF_RS04595	COG1914	H( )-stimulated, divalent metal cation uptake system
MINF_RS04605	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MINF_RS04615	COG4166	transmembrane transport
MINF_RS04625	COG0149	triose-phosphate isomerase activity
MINF_RS04630	COG0126	phosphoglycerate kinase activity
MINF_RS04635	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MINF_RS04640	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MINF_RS04640	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MINF_RS04650	COG1324	tolerance protein
MINF_RS04660	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MINF_RS04665	COG0740	serine-type endopeptidase activity
MINF_RS04670	COG0544	peptidyl-prolyl cis-trans isomerase activity
MINF_RS04675	COG0492	ferredoxin-NADP+ reductase activity
MINF_RS04685	COG0045	succinate-CoA ligase (ADP-forming) activity
MINF_RS04690	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MINF_RS04695	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MINF_RS04700	COG0204	Acyl-transferase
MINF_RS04700	COG0318	PFAM AMP-dependent synthetase and ligase
MINF_RS04710	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MINF_RS04710	COG1918	ferrous iron import across plasma membrane
MINF_RS04725	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MINF_RS04730	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MINF_RS04745	COG0412	Dienelactone hydrolase
MINF_RS04750	COG1216	Glycosyl transferase, family 2
MINF_RS04775	COG1881	PFAM PEBP family protein
MINF_RS04795	COG0004	ammonium transporteR
MINF_RS04800	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MINF_RS04800	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MINF_RS04805	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MINF_RS04810	COG0019	diaminopimelate decarboxylase activity
MINF_RS04815	COG1335	isochorismatase
MINF_RS04820	COG0347	Belongs to the P(II) protein family
MINF_RS04825	COG0432	Pfam Uncharacterised protein family UPF0047
MINF_RS04830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MINF_RS04845	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MINF_RS04850	COG4106	trans-aconitate 2-methyltransferase activity
MINF_RS04855	COG1017	nitric oxide dioxygenase activity
MINF_RS04855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MINF_RS04865	COG2223	nitrite transmembrane transporter activity
MINF_RS04875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MINF_RS04880	COG0243	molybdopterin cofactor binding
MINF_RS04890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MINF_RS04890	COG1116	anion transmembrane transporter activity
MINF_RS04945	COG2345	Transcriptional regulator
MINF_RS04950	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MINF_RS04955	COG0113	porphobilinogen synthase activity
MINF_RS04960	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MINF_RS04965	COG0571	ribonuclease III activity
MINF_RS04970	COG4974	Belongs to the 'phage' integrase family
MINF_RS04975	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MINF_RS04980	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MINF_RS04990	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MINF_RS05005	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MINF_RS05015	COG0138	bifunctional purine biosynthesis protein purh
MINF_RS05025	COG2226	methyltransferase
MINF_RS05045	COG2897	thiosulfate sulfurtransferase activity
MINF_RS05050	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MINF_RS05055	COG3852	Histidine kinase
MINF_RS05060	COG2204	response regulator
MINF_RS05075	COG3118	belongs to the thioredoxin family
MINF_RS05085	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MINF_RS05090	COG1573	uracil-dna glycosylase
MINF_RS05095	COG0564	pseudouridine synthase activity
MINF_RS05115	COG0259	pyridoxamine-phosphate oxidase activity
MINF_RS05290	COG1475	DNA binding
MINF_RS05295	COG1191	sigma factor activity
MINF_RS05350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MINF_RS05355	COG0347	Belongs to the P(II) protein family
MINF_RS05375	COG0438	transferase activity, transferring glycosyl groups
MINF_RS05380	COG0671	phosphoesterase, PA-phosphatase related
MINF_RS05385	COG1104	cysteine desulfurase activity
MINF_RS05395	COG0537	adenosine 5'-monophosphoramidase activity
MINF_RS05400	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MINF_RS05410	COG0416	fatty acid biosynthetic process
MINF_RS05415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MINF_RS05425	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MINF_RS05430	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MINF_RS05475	COG2094	Belongs to the DNA glycosylase MPG family
MINF_RS05485	COG3383	formate dehydrogenase (NAD+) activity
MINF_RS05505	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MINF_RS05510	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
MINF_RS05515	COG0535	radical SAM domain protein
MINF_RS05520	COG0535	radical SAM domain protein
MINF_RS05535	COG0423	glycine-tRNA ligase activity
MINF_RS05545	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MINF_RS05560	COG0590	tRNA wobble adenosine to inosine editing
MINF_RS05575	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MINF_RS05600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MINF_RS05610	COG3189	MarR family transcriptional regulator
MINF_RS05625	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MINF_RS05630	COG0572	uridine kinase
MINF_RS05645	COG1850	ribulose-bisphosphate carboxylase activity
MINF_RS05655	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MINF_RS05660	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MINF_RS05665	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MINF_RS05675	COG0792	nuclease activity
MINF_RS05680	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MINF_RS05685	COG0335	large ribosomal subunit rRNA binding
MINF_RS05690	COG0336	Belongs to the RNA methyltransferase TrmD family
MINF_RS05695	COG0228	four-way junction DNA binding
MINF_RS05700	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MINF_RS05705	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MINF_RS05715	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MINF_RS05725	COG4122	O-methyltransferase activity
MINF_RS05730	COG1222	aaa ATPase
MINF_RS05735	COG0284	orotidine-5'-phosphate decarboxylase activity
MINF_RS05740	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MINF_RS05750	COG0602	queuosine metabolic process
MINF_RS05765	COG1872	DUF167
MINF_RS05770	COG0667	Aldo Keto reductase
MINF_RS05780	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MINF_RS05815	COG3387	PFAM Glycoside hydrolase 15-related
MINF_RS05820	COG0655	NAD(P)H dehydrogenase (quinone) activity
MINF_RS05850	COG2062	phosphohistidine phosphatase, SixA
MINF_RS05860	COG2217	Heavy metal translocating P-type atpase
MINF_RS05875	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
MINF_RS05880	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
MINF_RS05915	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MINF_RS05925	COG0438	transferase activity, transferring glycosyl groups
MINF_RS05930	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MINF_RS06000	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MINF_RS06005	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MINF_RS06030	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MINF_RS06040	COG0799	negative regulation of ribosome biogenesis
MINF_RS06045	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MINF_RS06050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MINF_RS06055	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MINF_RS06060	COG0105	UTP biosynthetic process
MINF_RS06065	COG0436	Aminotransferase
MINF_RS06090	COG3876	Protein conserved in bacteria
MINF_RS06095	COG1994	Peptidase M50
MINF_RS06100	COG0489	protein tyrosine kinase activity
MINF_RS06135	COG1490	D-aminoacyl-tRNA deacylase activity
MINF_RS06180	COG1595	DNA-templated transcription, initiation
MINF_RS06190	COG3481	metal-dependent phosphohydrolase, HD sub domain
MINF_RS06195	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MINF_RS06205	COG1132	(ABC) transporter
MINF_RS06210	COG1910	domain protein
MINF_RS06215	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MINF_RS06230	COG1181	Belongs to the D-alanine--D-alanine ligase family
MINF_RS06235	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MINF_RS06240	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MINF_RS06245	COG0772	Belongs to the SEDS family
MINF_RS06250	COG0791	NLP P60 protein
MINF_RS06250	COG1388	LysM domain
MINF_RS06255	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MINF_RS06260	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MINF_RS06265	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MINF_RS06270	COG0768	penicillin binding
MINF_RS06280	COG0275	rRNA processing
MINF_RS06285	COG2001	Belongs to the MraZ family
MINF_RS06295	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MINF_RS06300	COG2304	oxidoreductase activity
MINF_RS06310	COG0714	Associated with various cellular activities
MINF_RS06315	COG1612	heme a metabolic process
MINF_RS06320	COG0109	protoheme IX farnesyltransferase activity
MINF_RS06340	COG1217	gtp-binding protein TYPA
MINF_RS06345	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
MINF_RS06355	COG1322	Protein conserved in bacteria
MINF_RS06360	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MINF_RS06365	COG0203	ribosomal protein L17
MINF_RS06370	COG0202	RNA polymerase activity
MINF_RS06375	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MINF_RS06385	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MINF_RS06390	COG0024	Methionine aminopeptidase
MINF_RS06395	COG0268	Binds directly to 16S ribosomal RNA
MINF_RS06400	COG0018	arginyl-trna synthetase
MINF_RS06410	COG4585	Histidine kinase
MINF_RS06440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MINF_RS06445	COG0156	8-amino-7-oxononanoate synthase activity
MINF_RS06450	COG0402	S-adenosylhomocysteine deaminase activity
MINF_RS06455	COG0671	phosphoesterase, PA-phosphatase related
MINF_RS06460	COG2217	Heavy metal translocating P-type atpase
MINF_RS06465	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MINF_RS06515	COG1132	(ABC) transporter
MINF_RS06560	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MINF_RS06610	COG0363	glucosamine-6-phosphate deaminase activity
MINF_RS06625	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MINF_RS06690	COG2197	response regulator
MINF_RS06700	COG0842	Transport permease protein
MINF_RS06705	COG0842	Transport permease protein
MINF_RS06710	COG1131	(ABC) transporter
MINF_RS06730	COG1686	Belongs to the peptidase S11 family
MINF_RS06745	COG1215	transferase activity, transferring glycosyl groups
MINF_RS06755	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MINF_RS06785	COG0531	amino acid
MINF_RS06790	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MINF_RS06805	COG0137	argininosuccinate synthase activity
MINF_RS06810	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MINF_RS06815	COG1722	exodeoxyribonuclease VII activity
MINF_RS06825	COG0525	valine-tRNA ligase activity
MINF_RS06830	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MINF_RS06835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MINF_RS06840	COG0358	DNA primase activity
MINF_RS06850	COG3956	TIGRFAM MazG family protein
MINF_RS06890	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MINF_RS06895	COG1058	Belongs to the CinA family
MINF_RS06895	COG1546	Belongs to the CinA family
MINF_RS06900	COG0653	protein targeting
MINF_RS06905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MINF_RS06910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MINF_RS06915	COG0505	Belongs to the CarA family
MINF_RS06920	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MINF_RS06925	COG0540	Belongs to the ATCase OTCase family
MINF_RS06930	COG0066	3-isopropylmalate dehydratase activity
MINF_RS06950	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MINF_RS06965	COG2967	ApaG domain
MINF_RS06970	COG0351	phosphomethylpyrimidine kinase
MINF_RS06970	COG0352	thiamine-phosphate diphosphorylase activity
MINF_RS06975	COG0604	alcohol dehydrogenase
MINF_RS06995	COG1543	Belongs to the glycosyl hydrolase 57 family
MINF_RS07010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MINF_RS07020	COG0798	PFAM Bile acid sodium symporter
MINF_RS07040	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MINF_RS07040	COG0574	Belongs to the PEP-utilizing enzyme family
MINF_RS07065	COG0346	lactoylglutathione lyase activity
MINF_RS07080	COG0277	FAD linked oxidase domain protein
MINF_RS07085	COG0247	lactate metabolic process
MINF_RS07105	COG1515	deoxyribonuclease V activity
MINF_RS07125	COG1252	NADH dehydrogenase
MINF_RS07130	COG1515	deoxyribonuclease V activity
MINF_RS07135	COG0375	protein maturation
MINF_RS07145	COG2943	transferase activity, transferring hexosyl groups
MINF_RS07155	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
MINF_RS07160	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
MINF_RS07175	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MINF_RS07175	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MINF_RS07185	COG0501	Belongs to the peptidase M48B family
MINF_RS07190	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MINF_RS07190	COG0646	methionine synthase
MINF_RS07205	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MINF_RS07210	COG1121	(ABC) transporter
MINF_RS07215	COG0803	Belongs to the bacterial solute-binding protein 9 family
MINF_RS07225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MINF_RS07230	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MINF_RS07230	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MINF_RS07235	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MINF_RS07245	COG0546	phosphoglycolate phosphatase activity
MINF_RS07250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MINF_RS07255	COG0215	cysteine-tRNA ligase activity
MINF_RS07260	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MINF_RS07270	COG0511	ligase activity, forming carbon-carbon bonds
MINF_RS07285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MINF_RS07360	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MINF_RS07365	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MINF_RS07365	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MINF_RS07375	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MINF_RS07380	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MINF_RS07385	COG0825	malonyl-CoA metabolic process
MINF_RS07400	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MINF_RS07405	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MINF_RS07415	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MINF_RS07420	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MINF_RS07425	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MINF_RS07445	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MINF_RS07450	COG2188	Transcriptional regulator
MINF_RS07455	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MINF_RS07465	COG3954	Phosphoribulokinase
MINF_RS07470	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
MINF_RS07490	COG0442	prolyl-tRNA aminoacylation
MINF_RS07495	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MINF_RS07500	COG0154	amidase activity
MINF_RS07505	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MINF_RS07530	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MINF_RS07540	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MINF_RS07545	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MINF_RS07580	COG0710	3-dehydroquinate dehydratase activity
MINF_RS07585	COG1077	Cell shape determining protein MreB Mrl
MINF_RS07590	COG1792	Involved in formation and maintenance of cell shape
MINF_RS07600	COG0768	penicillin binding
MINF_RS07605	COG0772	Belongs to the SEDS family
MINF_RS07610	COG1530	ribonuclease E activity
MINF_RS07615	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MINF_RS07625	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MINF_RS07640	COG0151	Belongs to the GarS family
MINF_RS07645	COG0501	Belongs to the peptidase M48B family
MINF_RS07650	COG1012	belongs to the aldehyde dehydrogenase family
MINF_RS07660	COG2322	membrane
MINF_RS07675	COG1131	(ABC) transporter
MINF_RS07680	COG1519	Transferase
MINF_RS07685	COG4974	Belongs to the 'phage' integrase family
MINF_RS07690	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MINF_RS07705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MINF_RS07710	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MINF_RS07715	COG0440	acetolactate synthase activity
MINF_RS07720	COG1254	Belongs to the acylphosphatase family
MINF_RS07725	COG1472	Belongs to the glycosyl hydrolase 3 family
MINF_RS07740	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MINF_RS07745	COG1480	7TM receptor with intracellular HD hydrolase
MINF_RS07750	COG1702	phosphate starvation-inducible protein PhoH
MINF_RS07760	COG0297	glycogen (starch) synthase activity
MINF_RS07775	COG0095	Lipoate-protein ligase
MINF_RS07785	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MINF_RS07790	COG0512	Glutamine amidotransferase of anthranilate synthase
MINF_RS07810	COG0811	peptide transport
MINF_RS07820	COG0438	transferase activity, transferring glycosyl groups
MINF_RS07825	COG2226	methyltransferase
MINF_RS07830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MINF_RS07850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MINF_RS07885	COG1595	DNA-templated transcription, initiation
MINF_RS07895	COG2226	methyltransferase
MINF_RS07900	COG0531	amino acid
MINF_RS07920	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MINF_RS07930	COG0409	Hydrogenase expression formation protein
MINF_RS07940	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
MINF_RS07950	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MINF_RS07960	COG4221	oxidoreductase activity
MINF_RS08005	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
MINF_RS08005	COG0662	Cupin 2, conserved barrel domain protein
MINF_RS08020	COG0693	protein deglycase activity
MINF_RS08025	COG0233	cytoplasmic translational termination
MINF_RS08030	COG0528	UMP kinase activity
MINF_RS08035	COG0556	nucleotide-excision repair
MINF_RS08050	COG1482	cell wall glycoprotein biosynthetic process
MINF_RS08055	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MINF_RS08060	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MINF_RS08060	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MINF_RS08090	COG0277	FAD linked oxidase domain protein
MINF_RS08095	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MINF_RS08105	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MINF_RS08125	COG0586	Pfam SNARE associated Golgi protein
MINF_RS08130	COG1363	Peptidase, m42
MINF_RS08140	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MINF_RS08150	COG1012	belongs to the aldehyde dehydrogenase family
MINF_RS08165	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MINF_RS08170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MINF_RS08185	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MINF_RS08205	COG2885	chlorophyll binding
MINF_RS08210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MINF_RS08230	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MINF_RS08235	COG0673	inositol 2-dehydrogenase activity
MINF_RS08245	COG0195	Participates in both transcription termination and antitermination
MINF_RS08255	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MINF_RS08260	COG0601	transmembrane transport
MINF_RS08265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MINF_RS08270	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MINF_RS08285	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
MINF_RS08290	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
MINF_RS08295	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
MINF_RS08310	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MINF_RS08315	COG0175	sulfate reduction
MINF_RS08320	COG0175	sulfate reduction
MINF_RS08330	COG0314	molybdopterin synthase activity
MINF_RS08340	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MINF_RS08350	COG0612	Peptidase, M16
MINF_RS08365	COG1663	tetraacyldisaccharide 4'-kinase activity
MINF_RS08370	COG0859	PFAM glycosyl transferase family 9
MINF_RS08375	COG0728	peptidoglycan biosynthetic process
MINF_RS08390	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MINF_RS08400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MINF_RS08415	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MINF_RS08430	COG1796	DNA polymerase
MINF_RS08430	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MINF_RS08435	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MINF_RS08455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MINF_RS08475	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
MINF_RS08485	COG0163	prenyltransferase activity
MINF_RS08500	COG2197	response regulator
MINF_RS08505	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MINF_RS08510	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MINF_RS08515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MINF_RS08520	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MINF_RS08525	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MINF_RS08530	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MINF_RS08555	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MINF_RS08560	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
MINF_RS08570	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MINF_RS08575	COG1862	Preprotein translocase
MINF_RS08580	COG0343	queuine tRNA-ribosyltransferase activity
MINF_RS08610	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MINF_RS08635	COG1845	cytochrome c oxidase, subunit III
MINF_RS08640	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MINF_RS08685	COG0437	4 iron, 4 sulfur cluster binding
MINF_RS08705	COG1496	oxidoreductase activity
MINF_RS08720	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MINF_RS08730	COG0750	zinc metalloprotease
MINF_RS08735	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MINF_RS08740	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MINF_RS08745	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MINF_RS08750	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MINF_RS08755	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MINF_RS08760	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MINF_RS08770	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MINF_RS08800	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MINF_RS08800	COG0438	transferase activity, transferring glycosyl groups
MINF_RS08815	COG2130	NADP-dependent
MINF_RS08820	COG3281	Trehalose synthase
MINF_RS08825	COG0366	Alpha amylase catalytic
MINF_RS08845	COG3391	amine dehydrogenase activity
MINF_RS08855	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MINF_RS08875	COG0837	glucose binding
MINF_RS08910	COG0583	DNA-binding transcription factor activity
MINF_RS08930	COG1067	ATP-dependent peptidase activity
MINF_RS08955	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MINF_RS08960	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MINF_RS08965	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MINF_RS08975	COG0133	tryptophan synthase activity
MINF_RS08980	COG0135	phosphoribosylanthranilate isomerase activity
MINF_RS08985	COG0134	indole-3-glycerol-phosphate synthase activity
MINF_RS09035	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MINF_RS09040	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MINF_RS09040	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MINF_RS09065	COG1216	Glycosyl transferase, family 2
MINF_RS09120	COG1216	Glycosyl transferase, family 2
MINF_RS09135	COG2226	methyltransferase
MINF_RS09175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MINF_RS09210	COG0527	aspartate kinase activity
MINF_RS09245	COG2204	response regulator
MINF_RS09250	COG3852	Histidine kinase
MINF_RS09255	COG0860	N-Acetylmuramoyl-L-alanine amidase
MINF_RS09260	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MINF_RS09265	COG0861	Integral membrane protein TerC family
MINF_RS09285	COG1166	arginine decarboxylase activity
MINF_RS09290	COG0583	DNA-binding transcription factor activity
MINF_RS09295	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MINF_RS09305	COG1959	2 iron, 2 sulfur cluster binding
MINF_RS09335	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MINF_RS09340	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MINF_RS09350	COG0205	6-phosphofructokinase activity
MINF_RS09360	COG1185	polyribonucleotide nucleotidyltransferase activity
MINF_RS09365	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MINF_RS09370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MINF_RS09375	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MINF_RS09390	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MINF_RS09390	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MINF_RS09400	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MINF_RS09405	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MINF_RS09405	COG0116	Belongs to the methyltransferase superfamily
MINF_RS09410	COG4608	Belongs to the ABC transporter superfamily
MINF_RS09415	COG0444	Belongs to the ABC transporter superfamily
MINF_RS09420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MINF_RS09425	COG0601	transmembrane transport
MINF_RS09450	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MINF_RS09455	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MINF_RS09460	COG0196	riboflavin kinase activity
MINF_RS09485	COG1566	PFAM secretion protein HlyD family protein
MINF_RS09490	COG0589	response to stress
MINF_RS09505	COG0446	pyridine nucleotide-disulphide oxidoreductase
MINF_RS09535	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MINF_RS09540	COG0509	glycine decarboxylation via glycine cleavage system
MINF_RS09560	COG0617	tRNA 3'-terminal CCA addition
MINF_RS09570	COG0459	protein refolding
MINF_RS09575	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MINF_RS09580	COG0443	Heat shock 70 kDa protein
MINF_RS09585	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MINF_RS09595	COG0590	tRNA wobble adenosine to inosine editing
MINF_RS09605	COG0354	folic acid binding
MINF_RS09625	COG0181	hydroxymethylbilane synthase activity
MINF_RS09630	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MINF_RS09650	COG0006	proline dipeptidase activity
MINF_RS09660	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MINF_RS09670	COG0745	RESPONSE REGULATOR receiver
MINF_RS09715	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
MINF_RS09725	COG1007	ATP synthesis coupled electron transport
MINF_RS09730	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MINF_RS09735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MINF_RS09740	COG0713	ATP synthesis coupled electron transport
MINF_RS09750	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MINF_RS09755	COG0667	Aldo Keto reductase
MINF_RS09765	COG0693	protein deglycase activity
MINF_RS09775	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MINF_RS09810	COG0297	glycogen (starch) synthase activity
MINF_RS09880	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MINF_RS09890	COG1213	nucleotidyl transferase
MINF_RS09900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MINF_RS09910	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MINF_RS09915	COG0484	heat shock protein binding
MINF_RS09925	COG2208	phosphoserine phosphatase activity
MINF_RS09935	COG1234	tRNA 3'-trailer cleavage
MINF_RS09940	COG0084	hydrolase, TatD family'
MINF_RS09945	COG0129	dihydroxy-acid dehydratase activity
MINF_RS09950	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MINF_RS09955	COG0072	phenylalanine-tRNA ligase activity
MINF_RS09975	COG3011	Protein conserved in bacteria
MINF_RS09980	COG0463	Glycosyl transferase, family 2
MINF_RS09985	COG0726	polysaccharide deacetylase
MINF_RS09995	COG0107	imidazoleglycerol-phosphate synthase activity
MINF_RS10000	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MINF_RS10010	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
MINF_RS10020	COG0101	tRNA pseudouridine synthase activity
MINF_RS10030	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MINF_RS10050	COG1388	LysM domain
MINF_RS10050	COG0791	NLP P60 protein
MINF_RS10085	COG0606	chelatase, subunit chli
MINF_RS10100	COG2135	peptidase activity
MINF_RS10115	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MINF_RS10125	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MINF_RS10135	COG0047	phosphoribosylformylglycinamidine synthase activity
MINF_RS10175	COG0590	tRNA wobble adenosine to inosine editing
MINF_RS10205	COG0811	peptide transport
MINF_RS10210	COG2814	Major facilitator Superfamily
MINF_RS10230	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MINF_RS10295	COG0811	peptide transport
MINF_RS10315	COG0297	glycogen (starch) synthase activity
MINF_RS10330	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MINF_RS10335	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MINF_RS10340	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MINF_RS10345	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MINF_RS10350	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MINF_RS10355	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MINF_RS10360	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MINF_RS10375	COG0028	Belongs to the TPP enzyme family
MINF_RS10435	COG0543	2 iron, 2 sulfur cluster binding
MINF_RS10445	COG0167	dihydroorotate dehydrogenase activity
MINF_RS10450	COG1013	pyruvate-flavodoxin oxidoreductase activity
MINF_RS10450	COG0674	pyruvate-flavodoxin oxidoreductase activity
MINF_RS10450	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MINF_RS10450	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MINF_RS10465	COG0543	2 iron, 2 sulfur cluster binding
MINF_RS10490	COG0307	riboflavin synthase, alpha
MINF_RS10510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MINF_RS10515	COG0445	tRNA wobble uridine modification
MINF_RS10520	COG0305	Participates in initiation and elongation during chromosome replication
MINF_RS10535	COG2022	thiamine diphosphate biosynthetic process
MINF_RS10540	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
MINF_RS10545	COG0123	including yeast histone deacetylase and acetoin utilization protein
MINF_RS10550	COG2010	Cytochrome c
MINF_RS10555	COG0083	homoserine kinase activity
MINF_RS10585	COG0356	it plays a direct role in the translocation of protons across the membrane
MINF_RS10595	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MINF_RS10605	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MINF_RS10610	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MINF_RS10615	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MINF_RS10630	COG0037	tRNA processing
MINF_RS10635	COG1187	pseudouridine synthase activity
MINF_RS10640	COG0165	Argininosuccinate lyase
MINF_RS10645	COG1333	cytochrome c biogenesis protein
MINF_RS10645	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MINF_RS10650	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MINF_RS10650	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MINF_RS10670	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
MINF_RS10690	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
MINF_RS10695	COG1272	protein, Hemolysin III
MINF_RS10705	COG0577	efflux transmembrane transporter activity
MINF_RS10710	COG1136	(ABC) transporter
MINF_RS10725	COG0811	peptide transport
MINF_RS10730	COG0848	biopolymer transport protein
MINF_RS10740	COG0823	Involved in the tonB-independent uptake of proteins
MINF_RS10745	COG2885	chlorophyll binding
MINF_RS10775	COG2146	nitrite reductase [NAD(P)H] activity
MINF_RS10780	COG1376	ErfK ybiS ycfS ynhG family protein
MINF_RS10790	COG0396	ATPase activity
MINF_RS10795	COG0719	Fe-S assembly protein
MINF_RS10800	COG0719	Fe-S assembly protein
MINF_RS10805	COG2151	metal-sulfur cluster biosynthetic enzyme
MINF_RS10820	COG1090	epimerase
MINF_RS10830	COG1045	serine acetyltransferase
MINF_RS10835	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MINF_RS10850	COG2226	methyltransferase
MINF_RS10860	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate