locus-tag	class	description
MRAD2831_RS32020	COG0268	Binds directly to 16S ribosomal RNA
MRAD2831_RS32025	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MRAD2831_RS32030	COG0183	Belongs to the thiolase family
MRAD2831_RS32040	COG5001	Diguanylate cyclase
MRAD2831_RS32045	COG1250	3-hydroxyacyl-CoA dehydrogenase
MRAD2831_RS32045	COG1024	Enoyl-CoA hydratase
MRAD2831_RS32055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MRAD2831_RS32070	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MRAD2831_RS32110	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MRAD2831_RS32120	COG0343	queuine tRNA-ribosyltransferase activity
MRAD2831_RS32125	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MRAD2831_RS32155	COG3346	SURF1 family
MRAD2831_RS32170	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
MRAD2831_RS32180	COG0109	protoheme IX farnesyltransferase activity
MRAD2831_RS32185	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MRAD2831_RS32195	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MRAD2831_RS32205	COG0070	glutamate synthase
MRAD2831_RS32205	COG0067	glutamate synthase
MRAD2831_RS32205	COG0069	glutamate synthase activity
MRAD2831_RS32220	COG2951	lytic endotransglycosylase activity
MRAD2831_RS32230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MRAD2831_RS32265	COG1238	metal cluster binding
MRAD2831_RS32280	COG0123	including yeast histone deacetylase and acetoin utilization protein
MRAD2831_RS32290	COG0800	Aldolase
MRAD2831_RS32295	COG3734	2-keto-3-deoxy-galactonokinase
MRAD2831_RS32315	COG0559	Belongs to the binding-protein-dependent transport system permease family
MRAD2831_RS32320	COG4214	carbohydrate transport
MRAD2831_RS32340	COG0318	PFAM AMP-dependent synthetase and ligase
MRAD2831_RS32355	COG1396	sequence-specific DNA binding
MRAD2831_RS32365	COG0742	ribosomal rna small subunit methyltransferase
MRAD2831_RS32370	COG1187	pseudouridine synthase activity
MRAD2831_RS32380	COG3237	CsbD-like
MRAD2831_RS32385	COG0590	tRNA wobble adenosine to inosine editing
MRAD2831_RS32400	COG4957	zinc ion binding
MRAD2831_RS32405	COG2814	Major facilitator Superfamily
MRAD2831_RS32410	COG2902	Dehydrogenase
MRAD2831_RS32420	COG2271	Major facilitator Superfamily
MRAD2831_RS32425	COG2814	Major facilitator Superfamily
MRAD2831_RS32430	COG2259	Doxx family
MRAD2831_RS32435	COG0477	Major facilitator Superfamily
MRAD2831_RS32450	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MRAD2831_RS32455	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MRAD2831_RS32455	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MRAD2831_RS32460	COG0657	acetylesterase activity
MRAD2831_RS32460	COG2755	lipolytic protein G-D-S-L family
MRAD2831_RS32500	COG0494	nUDIX hydrolase
MRAD2831_RS32510	COG0793	Belongs to the peptidase S41A family
MRAD2831_RS32520	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MRAD2831_RS32525	COG0799	negative regulation of ribosome biogenesis
MRAD2831_RS32535	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MRAD2831_RS32540	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MRAD2831_RS32545	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MRAD2831_RS32555	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MRAD2831_RS32560	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MRAD2831_RS32575	COG0632	four-way junction helicase activity
MRAD2831_RS32585	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MRAD2831_RS32590	COG0588	phosphoglycerate mutase activity
MRAD2831_RS32600	COG3739	integral membrane protein
MRAD2831_RS32625	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MRAD2831_RS32630	COG3750	Belongs to the UPF0335 family
MRAD2831_RS32655	COG0469	pyruvate kinase activity
MRAD2831_RS32660	COG0596	Alpha beta hydrolase
MRAD2831_RS32670	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MRAD2831_RS32685	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MRAD2831_RS32690	COG0527	aspartate kinase activity
MRAD2831_RS32695	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MRAD2831_RS32700	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MRAD2831_RS32705	COG2890	protein-(glutamine-N5) methyltransferase activity
MRAD2831_RS32720	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MRAD2831_RS32725	COG0248	Ppx GppA phosphatase
MRAD2831_RS32735	COG1278	Cold shock
MRAD2831_RS32760	COG1012	belongs to the aldehyde dehydrogenase family
MRAD2831_RS32790	COG0352	thiamine-phosphate diphosphorylase activity
MRAD2831_RS32805	COG0126	phosphoglycerate kinase activity
MRAD2831_RS32830	COG1733	regulation of RNA biosynthetic process
MRAD2831_RS32835	COG0702	epimerase
MRAD2831_RS32840	COG2186	Transcriptional regulator
MRAD2831_RS32850	COG3052	prosthetic group binding
MRAD2831_RS32880	COG1012	belongs to the aldehyde dehydrogenase family
MRAD2831_RS32890	COG2244	polysaccharide biosynthetic process
MRAD2831_RS32905	COG0438	transferase activity, transferring glycosyl groups
MRAD2831_RS32910	COG0438	transferase activity, transferring glycosyl groups
MRAD2831_RS32915	COG3206	protein involved in exopolysaccharide biosynthesis
MRAD2831_RS32915	COG0489	protein tyrosine kinase activity
MRAD2831_RS32925	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MRAD2831_RS32930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MRAD2831_RS32940	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MRAD2831_RS32950	COG3250	beta-galactosidase activity
MRAD2831_RS32970	COG1294	oxidase, subunit
MRAD2831_RS32975	COG1271	oxidase subunit
MRAD2831_RS33015	COG2080	2 iron, 2 sulfur cluster binding
MRAD2831_RS33015	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MRAD2831_RS33020	COG2252	PERMEase
MRAD2831_RS33025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MRAD2831_RS33035	COG2205	protein histidine kinase activity
MRAD2831_RS33040	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MRAD2831_RS33045	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MRAD2831_RS33055	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MRAD2831_RS33075	COG0784	Response regulator, receiver
MRAD2831_RS33090	COG3300	MHYT domain
MRAD2831_RS33090	COG5001	Diguanylate cyclase
MRAD2831_RS33120	COG2205	protein histidine kinase activity
MRAD2831_RS33125	COG0745	RESPONSE REGULATOR receiver
MRAD2831_RS33155	COG0154	amidase activity
MRAD2831_RS33160	COG2271	Major facilitator Superfamily
MRAD2831_RS33165	COG3048	D-serine ammonia-lyase activity
MRAD2831_RS33170	COG0583	DNA-binding transcription factor activity
MRAD2831_RS33175	COG0583	DNA-binding transcription factor activity
MRAD2831_RS33200	COG0297	glycogen (starch) synthase activity
MRAD2831_RS33220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MRAD2831_RS33245	COG2144	transferase activity, transferring acyl groups
MRAD2831_RS33250	COG0438	transferase activity, transferring glycosyl groups
MRAD2831_RS33255	COG2072	flavoprotein involved in K transport
MRAD2831_RS33265	COG0840	transmembrane signaling receptor activity
MRAD2831_RS33305	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MRAD2831_RS33320	COG0697	spore germination
MRAD2831_RS33330	COG0778	Nitroreductase
MRAD2831_RS33335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MRAD2831_RS33370	COG1215	transferase activity, transferring glycosyl groups
MRAD2831_RS33395	COG0739	heme binding
MRAD2831_RS33415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MRAD2831_RS33460	COG1253	flavin adenine dinucleotide binding
MRAD2831_RS33490	COG0583	DNA-binding transcription factor activity
MRAD2831_RS33495	COG1942	4-Oxalocrotonate Tautomerase
MRAD2831_RS33500	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MRAD2831_RS33555	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MRAD2831_RS33570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MRAD2831_RS33575	COG0667	Aldo Keto reductase
MRAD2831_RS33590	COG4585	Histidine kinase
MRAD2831_RS33640	COG4829	muconolactone delta-isomerase
MRAD2831_RS33645	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MRAD2831_RS33650	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MRAD2831_RS33655	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS33660	COG0410	ABC transporter
MRAD2831_RS33675	COG1063	alcohol dehydrogenase
MRAD2831_RS33680	COG1802	Transcriptional regulator
MRAD2831_RS33690	COG0840	transmembrane signaling receptor activity
MRAD2831_RS33730	COG0579	oxidoreductase
MRAD2831_RS33740	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
MRAD2831_RS33765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MRAD2831_RS33770	COG1126	abc transporter atp-binding protein
MRAD2831_RS33775	COG0765	amino acid transport
MRAD2831_RS33780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MRAD2831_RS33810	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MRAD2831_RS33815	COG1301	dicarboxylic acid transport
MRAD2831_RS33820	COG4191	Histidine kinase
MRAD2831_RS33825	COG2204	response regulator
MRAD2831_RS33865	COG2801	Transposase and inactivated derivatives
MRAD2831_RS33925	COG3300	MHYT domain
MRAD2831_RS33925	COG5001	Diguanylate cyclase
MRAD2831_RS33980	COG4191	Histidine kinase
MRAD2831_RS33985	COG4566	intracellular signal transduction
MRAD2831_RS34000	COG2274	protein secretion by the type I secretion system
MRAD2831_RS34010	COG0583	DNA-binding transcription factor activity
MRAD2831_RS34025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MRAD2831_RS34040	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MRAD2831_RS34055	COG0793	Belongs to the peptidase S41A family
MRAD2831_RS34060	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MRAD2831_RS34090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MRAD2831_RS34095	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MRAD2831_RS34100	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
MRAD2831_RS34190	COG2801	Transposase and inactivated derivatives
MRAD2831_RS34215	COG4989	oxidoreductase activity
MRAD2831_RS34240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MRAD2831_RS34240	COG0519	Catalyzes the synthesis of GMP from XMP
MRAD2831_RS34250	COG1720	tRNA m6t6A37 methyltransferase activity
MRAD2831_RS34255	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MRAD2831_RS34295	COG1132	(ABC) transporter
MRAD2831_RS34300	COG0723	plastoquinol--plastocyanin reductase activity
MRAD2831_RS34305	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MRAD2831_RS34305	COG2857	Cytochrome c1
MRAD2831_RS34310	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MRAD2831_RS34310	COG2857	Cytochrome c1
MRAD2831_RS34315	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MRAD2831_RS34320	COG0131	Imidazoleglycerol-phosphate dehydratase
MRAD2831_RS34330	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MRAD2831_RS34335	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MRAD2831_RS34340	COG0107	imidazoleglycerol-phosphate synthase activity
MRAD2831_RS34350	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MRAD2831_RS34355	COG0758	DNA mediated transformation
MRAD2831_RS34360	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MRAD2831_RS34375	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MRAD2831_RS34390	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MRAD2831_RS34395	COG1566	PFAM secretion protein HlyD family protein
MRAD2831_RS34415	COG0625	glutathione transferase activity
MRAD2831_RS34425	COG0105	UTP biosynthetic process
MRAD2831_RS34435	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MRAD2831_RS34440	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MRAD2831_RS34445	COG0628	permease
MRAD2831_RS34455	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MRAD2831_RS34460	COG0248	Ppx GppA phosphatase
MRAD2831_RS34475	COG0280	phosphate acetyltransferase
MRAD2831_RS34475	COG0281	malic enzyme
MRAD2831_RS34505	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MRAD2831_RS34515	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MRAD2831_RS34540	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MRAD2831_RS34545	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MRAD2831_RS34550	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MRAD2831_RS34565	COG0535	radical SAM domain protein
MRAD2831_RS34570	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
MRAD2831_RS34575	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MRAD2831_RS34585	COG0745	RESPONSE REGULATOR receiver
MRAD2831_RS34590	COG2205	protein histidine kinase activity
MRAD2831_RS34600	COG2218	PFAM glutamate synthase alpha subunit domain protein
MRAD2831_RS34605	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
MRAD2831_RS34610	COG1229	Formylmethanofuran dehydrogenase subunit A
MRAD2831_RS34615	COG1029	Formylmethanofuran dehydrogenase, subunit B
MRAD2831_RS34625	COG0702	epimerase
MRAD2831_RS34640	COG0189	ligase activity
MRAD2831_RS34650	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
MRAD2831_RS34660	COG0459	protein refolding
MRAD2831_RS34665	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MRAD2831_RS34685	COG1201	RNA secondary structure unwinding
MRAD2831_RS34690	COG0657	acetylesterase activity
MRAD2831_RS34720	COG0243	molybdopterin cofactor binding
MRAD2831_RS34740	COG4191	Histidine kinase
MRAD2831_RS34740	COG0784	Response regulator, receiver
MRAD2831_RS34750	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MRAD2831_RS34755	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MRAD2831_RS34760	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MRAD2831_RS34775	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MRAD2831_RS34785	COG0318	PFAM AMP-dependent synthetase and ligase
MRAD2831_RS34790	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MRAD2831_RS34800	COG0583	DNA-binding transcription factor activity
MRAD2831_RS34805	COG0492	ferredoxin-NADP+ reductase activity
MRAD2831_RS34820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MRAD2831_RS34825	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MRAD2831_RS34830	COG3794	PFAM blue (type 1) copper domain protein
MRAD2831_RS34840	COG0505	Belongs to the CarA family
MRAD2831_RS34850	COG0358	DNA primase activity
MRAD2831_RS34855	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MRAD2831_RS34875	COG2022	thiamine diphosphate biosynthetic process
MRAD2831_RS34875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MRAD2831_RS34885	COG2022	thiamine diphosphate biosynthetic process
MRAD2831_RS34890	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MRAD2831_RS34890	COG0352	thiamine-phosphate diphosphorylase activity
MRAD2831_RS34910	COG2308	Evidence 4 Homologs of previously reported genes of
MRAD2831_RS34915	COG2003	Belongs to the UPF0758 family
MRAD2831_RS34920	COG0024	Methionine aminopeptidase
MRAD2831_RS34930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MRAD2831_RS34965	COG1643	Atp-dependent helicase
MRAD2831_RS35000	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MRAD2831_RS35005	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MRAD2831_RS35010	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MRAD2831_RS35015	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MRAD2831_RS35020	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MRAD2831_RS35035	COG0137	argininosuccinate synthase activity
MRAD2831_RS35045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MRAD2831_RS35050	COG0142	geranyltranstransferase activity
MRAD2831_RS35055	COG4214	carbohydrate transport
MRAD2831_RS35065	COG4213	ABC transporter substrate-binding protein
MRAD2831_RS35070	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS35085	COG0596	Alpha beta hydrolase
MRAD2831_RS35095	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MRAD2831_RS35100	COG0784	Response regulator, receiver
MRAD2831_RS35110	COG2814	Major facilitator Superfamily
MRAD2831_RS35120	COG1285	pathogenesis
MRAD2831_RS35125	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MRAD2831_RS35130	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MRAD2831_RS35135	COG3180	Ammonia monooxygenase
MRAD2831_RS35140	COG0165	Argininosuccinate lyase
MRAD2831_RS35150	COG0753	catalase activity
MRAD2831_RS35160	COG2807	transmembrane transport
MRAD2831_RS35165	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MRAD2831_RS35170	COG1253	flavin adenine dinucleotide binding
MRAD2831_RS35175	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MRAD2831_RS35180	COG1702	phosphate starvation-inducible protein PhoH
MRAD2831_RS35185	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MRAD2831_RS35190	COG1620	l-lactate permease
MRAD2831_RS35210	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MRAD2831_RS35225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MRAD2831_RS35275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MRAD2831_RS35280	COG4608	Belongs to the ABC transporter superfamily
MRAD2831_RS35285	COG0444	Belongs to the ABC transporter superfamily
MRAD2831_RS35295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MRAD2831_RS35315	COG2267	carboxylic ester hydrolase activity
MRAD2831_RS35325	COG1570	exodeoxyribonuclease VII activity
MRAD2831_RS35330	COG0477	Major facilitator Superfamily
MRAD2831_RS35370	COG1846	Transcriptional regulator
MRAD2831_RS35375	COG4974	Belongs to the 'phage' integrase family
MRAD2831_RS35385	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MRAD2831_RS35390	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MRAD2831_RS35400	COG0651	ATP synthesis coupled electron transport
MRAD2831_RS35405	COG1006	Multisubunit Na H antiporter MnhC subunit
MRAD2831_RS35445	COG2873	o-acetylhomoserine
MRAD2831_RS35455	COG2945	thiolester hydrolase activity
MRAD2831_RS35460	COG1104	cysteine desulfurase activity
MRAD2831_RS35465	COG0719	Fe-S assembly protein
MRAD2831_RS35475	COG0396	ATPase activity
MRAD2831_RS35480	COG0719	Fe-S assembly protein
MRAD2831_RS35485	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MRAD2831_RS35510	COG1131	(ABC) transporter
MRAD2831_RS35515	COG0842	Transport permease protein
MRAD2831_RS35520	COG0596	Alpha beta hydrolase
MRAD2831_RS35530	COG1489	DNA binding
MRAD2831_RS35535	COG1546	Belongs to the CinA family
MRAD2831_RS35535	COG1058	Belongs to the CinA family
MRAD2831_RS35540	COG2116	formate transmembrane transporter activity
MRAD2831_RS35545	COG1252	NADH dehydrogenase
MRAD2831_RS35550	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MRAD2831_RS35555	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MRAD2831_RS35565	COG0356	it plays a direct role in the translocation of protons across the membrane
MRAD2831_RS35590	COG2189	Belongs to the N(4) N(6)-methyltransferase family
MRAD2831_RS35595	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MRAD2831_RS35610	COG0488	(ABC) transporter
MRAD2831_RS35615	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MRAD2831_RS35635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MRAD2831_RS35660	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MRAD2831_RS35665	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MRAD2831_RS35670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MRAD2831_RS35675	COG0653	protein targeting
MRAD2831_RS35680	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MRAD2831_RS35685	COG3158	transport of potassium into the cell
MRAD2831_RS35695	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MRAD2831_RS35700	COG2205	protein histidine kinase activity
MRAD2831_RS35720	COG0848	biopolymer transport protein
MRAD2831_RS35725	COG0811	peptide transport
MRAD2831_RS35735	COG0824	Thioesterase
MRAD2831_RS35745	COG2255	four-way junction helicase activity
MRAD2831_RS35780	COG0438	transferase activity, transferring glycosyl groups
MRAD2831_RS35785	COG2264	protein methyltransferase activity
MRAD2831_RS35795	COG3038	cytochrome b561
MRAD2831_RS35805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MRAD2831_RS35810	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MRAD2831_RS35850	COG2205	protein histidine kinase activity
MRAD2831_RS35865	COG0306	phosphate transporter
MRAD2831_RS35870	COG1392	Phosphate transport regulator
MRAD2831_RS35895	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MRAD2831_RS35900	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MRAD2831_RS35905	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
MRAD2831_RS35910	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
MRAD2831_RS35930	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MRAD2831_RS35940	COG1686	Belongs to the peptidase S11 family
MRAD2831_RS35955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MRAD2831_RS36000	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MRAD2831_RS36015	COG0556	nucleotide-excision repair
MRAD2831_RS36040	COG0657	acetylesterase activity
MRAD2831_RS36050	COG1335	isochorismatase
MRAD2831_RS36065	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MRAD2831_RS36070	COG4172	Belongs to the ABC transporter superfamily
MRAD2831_RS36095	COG4786	Flagellar basal body rod
MRAD2831_RS36100	COG4786	Flagellar basal body rod
MRAD2831_RS36115	COG0673	inositol 2-dehydrogenase activity
MRAD2831_RS36125	COG0671	phosphoesterase, PA-phosphatase related
MRAD2831_RS36150	COG0435	Glutathione S-transferase
MRAD2831_RS36160	COG3118	belongs to the thioredoxin family
MRAD2831_RS36170	COG2835	tetraacyldisaccharide 4'-kinase activity
MRAD2831_RS36220	COG4536	flavin adenine dinucleotide binding
MRAD2831_RS36225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MRAD2831_RS36240	COG0386	Belongs to the glutathione peroxidase family
MRAD2831_RS36260	COG0596	Alpha beta hydrolase
MRAD2831_RS36265	COG0564	pseudouridine synthase activity
MRAD2831_RS36275	COG4774	siderophore transport
MRAD2831_RS36290	COG0523	cobalamin synthesis protein
MRAD2831_RS36310	COG0156	8-amino-7-oxononanoate synthase activity
MRAD2831_RS36320	COG2226	methyltransferase
MRAD2831_RS36340	COG0189	ligase activity
MRAD2831_RS36370	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MRAD2831_RS36385	COG1595	DNA-templated transcription, initiation
MRAD2831_RS36405	COG0745	RESPONSE REGULATOR receiver
MRAD2831_RS36410	COG0196	riboflavin kinase activity
MRAD2831_RS36420	COG1663	tetraacyldisaccharide 4'-kinase activity
MRAD2831_RS36425	COG1519	Transferase
MRAD2831_RS36445	COG0154	amidase activity
MRAD2831_RS36465	COG0028	Belongs to the TPP enzyme family
MRAD2831_RS36470	COG0747	negative chemotaxis
MRAD2831_RS36475	COG0154	amidase activity
MRAD2831_RS36530	COG4953	penicillin-binding protein 1C
MRAD2831_RS36555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MRAD2831_RS36565	COG0039	L-malate dehydrogenase activity
MRAD2831_RS36570	COG0045	succinate-CoA ligase (ADP-forming) activity
MRAD2831_RS36575	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MRAD2831_RS36580	COG0567	Dehydrogenase, E1 component
MRAD2831_RS36590	COG0508	dehydrogenase complex catalyzes the overall conversion of
MRAD2831_RS36595	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS36600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MRAD2831_RS36610	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MRAD2831_RS36615	COG1742	UPF0060 membrane protein
MRAD2831_RS36620	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MRAD2831_RS36655	COG0251	oxidation-reduction process
MRAD2831_RS36660	COG2261	transglycosylase associated protein
MRAD2831_RS36670	COG1185	polyribonucleotide nucleotidyltransferase activity
MRAD2831_RS36675	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MRAD2831_RS36690	COG0531	amino acid
MRAD2831_RS36695	COG1558	bacterial-type flagellum-dependent cell motility
MRAD2831_RS36705	COG0300	oxidoreductase activity
MRAD2831_RS36730	COG0156	8-amino-7-oxononanoate synthase activity
MRAD2831_RS36735	COG3321	synthase
MRAD2831_RS36735	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS36735	COG0604	alcohol dehydrogenase
MRAD2831_RS36740	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MRAD2831_RS36745	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MRAD2831_RS36755	COG0335	large ribosomal subunit rRNA binding
MRAD2831_RS36760	COG0840	transmembrane signaling receptor activity
MRAD2831_RS36760	COG2972	Histidine kinase
MRAD2831_RS36770	COG2951	lytic endotransglycosylase activity
MRAD2831_RS36775	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MRAD2831_RS36790	COG0066	3-isopropylmalate dehydratase activity
MRAD2831_RS36820	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MRAD2831_RS36835	COG3394	polysaccharide catabolic process
MRAD2831_RS36865	COG0596	Alpha beta hydrolase
MRAD2831_RS36875	COG2877	3-deoxy-8-phosphooctulonate synthase activity
MRAD2831_RS36880	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MRAD2831_RS36890	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MRAD2831_RS36895	COG0148	phosphopyruvate hydratase activity
MRAD2831_RS36910	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MRAD2831_RS36915	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MRAD2831_RS36920	COG0022	dehydrogenase e1 component
MRAD2831_RS36920	COG0508	dehydrogenase complex catalyzes the overall conversion of
MRAD2831_RS36935	COG0508	dehydrogenase complex catalyzes the overall conversion of
MRAD2831_RS36945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MRAD2831_RS36960	COG0316	Belongs to the HesB IscA family
MRAD2831_RS36970	COG0513	Belongs to the DEAD box helicase family
MRAD2831_RS36980	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MRAD2831_RS36990	COG0187	DNA topoisomerase II activity
MRAD2831_RS37000	COG1754	DNA topoisomerase type I activity
MRAD2831_RS37000	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MRAD2831_RS37015	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MRAD2831_RS37025	COG0540	Belongs to the ATCase OTCase family
MRAD2831_RS37030	COG0140	phosphoribosyl-ATP diphosphatase activity
MRAD2831_RS37035	COG1072	(Pantothenic acid kinase))
MRAD2831_RS37050	COG4181	ATPase activity
MRAD2831_RS37070	COG0670	Belongs to the BI1 family
MRAD2831_RS37075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MRAD2831_RS37085	COG0778	Nitroreductase
MRAD2831_RS37090	COG1376	ErfK ybiS ycfS ynhG family protein
MRAD2831_RS37115	COG0688	phosphatidylethanolamine metabolic process
MRAD2831_RS37120	COG1183	phosphatidylcholine synthase activity
MRAD2831_RS37125	COG1970	mechanosensitive ion channel activity
MRAD2831_RS37145	COG0121	glutamine amidotransferase
MRAD2831_RS37160	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MRAD2831_RS37165	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MRAD2831_RS37190	COG0437	4 iron, 4 sulfur cluster binding
MRAD2831_RS37205	COG4988	ABC transporter
MRAD2831_RS37210	COG3034	peptidoglycan biosynthetic process
MRAD2831_RS37215	COG1234	tRNA 3'-trailer cleavage
MRAD2831_RS37235	COG2226	methyltransferase
MRAD2831_RS37250	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MRAD2831_RS37260	COG1024	Enoyl-CoA hydratase
MRAD2831_RS37270	COG1250	3-hydroxyacyl-CoA dehydrogenase
MRAD2831_RS37270	COG1024	Enoyl-CoA hydratase
MRAD2831_RS37275	COG0183	Belongs to the thiolase family
MRAD2831_RS37280	COG1960	acyl-CoA dehydrogenase activity
MRAD2831_RS37285	COG1960	acyl-CoA dehydrogenase activity
MRAD2831_RS37295	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MRAD2831_RS37325	COG1902	pentaerythritol trinitrate reductase activity
MRAD2831_RS37330	COG3698	Phosphodiester glycosidase
MRAD2831_RS37340	COG2814	Major facilitator Superfamily
MRAD2831_RS37355	COG0477	Major facilitator Superfamily
MRAD2831_RS37365	COG1917	Cupin 2, conserved barrel domain protein
MRAD2831_RS37365	COG1396	sequence-specific DNA binding
MRAD2831_RS37370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MRAD2831_RS37380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MRAD2831_RS37385	COG0583	DNA-binding transcription factor activity
MRAD2831_RS37400	COG0625	glutathione transferase activity
MRAD2831_RS37420	COG2249	NAD(P)H dehydrogenase (quinone) activity
MRAD2831_RS37430	COG2864	formate dehydrogenase
MRAD2831_RS37435	COG0437	4 iron, 4 sulfur cluster binding
MRAD2831_RS37440	COG3383	formate dehydrogenase (NAD+) activity
MRAD2831_RS37440	COG0243	molybdopterin cofactor binding
MRAD2831_RS37445	COG0243	molybdopterin cofactor binding
MRAD2831_RS37445	COG3383	formate dehydrogenase (NAD+) activity
MRAD2831_RS37460	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MRAD2831_RS37470	COG4208	sulfate ABC transporter
MRAD2831_RS37475	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MRAD2831_RS37495	COG2824	Alkylphosphonate utilization operon protein PhnA
MRAD2831_RS37500	COG0604	alcohol dehydrogenase
MRAD2831_RS37505	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MRAD2831_RS37505	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MRAD2831_RS37515	COG3293	Transposase
MRAD2831_RS37520	COG0840	transmembrane signaling receptor activity
MRAD2831_RS37525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MRAD2831_RS37535	COG1830	Aldolase
MRAD2831_RS37550	COG0071	Belongs to the small heat shock protein (HSP20) family
MRAD2831_RS37585	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MRAD2831_RS37590	COG0500	methyltransferase
MRAD2831_RS37595	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MRAD2831_RS37610	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MRAD2831_RS37615	COG0514	ATP-dependent DNA helicase (RecQ)
MRAD2831_RS37630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MRAD2831_RS37635	COG3395	kinase activity
MRAD2831_RS37640	COG3622	Belongs to the hyi family
MRAD2831_RS37645	COG2084	Dehydrogenase
MRAD2831_RS37650	COG2271	Major facilitator Superfamily
MRAD2831_RS37655	COG1609	Transcriptional regulator
MRAD2831_RS37660	COG0235	Class ii aldolase
MRAD2831_RS37665	COG0751	glycine-tRNA ligase activity
MRAD2831_RS37675	COG0752	glycyl-tRNA synthetase alpha subunit
MRAD2831_RS37705	COG0586	Pfam SNARE associated Golgi protein
MRAD2831_RS37710	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
MRAD2831_RS37715	COG0384	phenazine biosynthesis protein PhzF
MRAD2831_RS37755	COG3501	Rhs element vgr protein
MRAD2831_RS37840	COG1832	CoA-binding protein
MRAD2831_RS37845	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MRAD2831_RS37850	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MRAD2831_RS37885	COG0586	Pfam SNARE associated Golgi protein
MRAD2831_RS37935	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS37945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MRAD2831_RS37960	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS38035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MRAD2831_RS38050	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MRAD2831_RS38055	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MRAD2831_RS38060	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MRAD2831_RS38090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MRAD2831_RS38130	COG2205	protein histidine kinase activity
MRAD2831_RS38135	COG3706	GGDEF domain
MRAD2831_RS38145	COG1802	Transcriptional regulator
MRAD2831_RS38155	COG3842	ATPase activity
MRAD2831_RS38160	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MRAD2831_RS38180	COG0154	amidase activity
MRAD2831_RS38205	COG1215	transferase activity, transferring glycosyl groups
MRAD2831_RS38215	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MRAD2831_RS38220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MRAD2831_RS38255	COG4566	intracellular signal transduction
MRAD2831_RS38260	COG4566	intracellular signal transduction
MRAD2831_RS38265	COG0477	Major facilitator Superfamily
MRAD2831_RS38275	COG3059	membrane
MRAD2831_RS38295	COG4221	oxidoreductase activity
MRAD2831_RS38340	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MRAD2831_RS38365	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MRAD2831_RS38380	COG2801	Transposase and inactivated derivatives
MRAD2831_RS38415	COG3920	Histidine kinase
MRAD2831_RS38440	COG1132	(ABC) transporter
MRAD2831_RS38445	COG1609	Transcriptional regulator
MRAD2831_RS38480	COG1260	myo-inositol-1-phosphate synthase
MRAD2831_RS38510	COG1032	radical SAM domain protein
MRAD2831_RS38515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MRAD2831_RS38540	COG0129	dihydroxy-acid dehydratase activity
MRAD2831_RS38545	COG2186	Transcriptional regulator
MRAD2831_RS38570	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
MRAD2831_RS38590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MRAD2831_RS38595	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MRAD2831_RS38600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MRAD2831_RS38605	COG1116	anion transmembrane transporter activity
MRAD2831_RS38680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MRAD2831_RS38685	COG4989	oxidoreductase activity
MRAD2831_RS38690	COG1691	(AIR) carboxylase
MRAD2831_RS38695	COG1606	tRNA processing
MRAD2831_RS38700	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
MRAD2831_RS38710	COG1295	ribonuclease BN
MRAD2831_RS38715	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS38745	COG1733	regulation of RNA biosynthetic process
MRAD2831_RS38790	COG0431	NADPH-dependent FMN reductase
MRAD2831_RS38805	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MRAD2831_RS38830	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
MRAD2831_RS38865	COG3552	Protein containing von Willebrand factor type A (VWA) domain
MRAD2831_RS38870	COG3831	ATPase activity
MRAD2831_RS38880	COG2425	protein containing a von Willebrand factor type A (vWA) domain
MRAD2831_RS38885	COG0714	Associated with various cellular activities
MRAD2831_RS38955	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MRAD2831_RS38970	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS38985	COG1595	DNA-templated transcription, initiation
MRAD2831_RS39005	COG0604	alcohol dehydrogenase
MRAD2831_RS39005	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS39005	COG3321	synthase
MRAD2831_RS39010	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MRAD2831_RS39015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MRAD2831_RS39020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MRAD2831_RS39060	COG1172	Belongs to the binding-protein-dependent transport system permease family
MRAD2831_RS39070	COG0411	ABC transporter
MRAD2831_RS39100	COG0559	Belongs to the binding-protein-dependent transport system permease family
MRAD2831_RS39130	COG0784	Response regulator, receiver
MRAD2831_RS39130	COG2205	protein histidine kinase activity
MRAD2831_RS39140	COG2197	response regulator
MRAD2831_RS39150	COG0464	growth
MRAD2831_RS39155	COG0464	growth
MRAD2831_RS39220	COG0277	FAD linked oxidase domain protein
MRAD2831_RS39240	COG1492	cobalamin metabolic process
MRAD2831_RS39250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MRAD2831_RS39265	COG2814	Major facilitator Superfamily
MRAD2831_RS39280	COG0318	PFAM AMP-dependent synthetase and ligase
MRAD2831_RS39305	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
MRAD2831_RS39315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MRAD2831_RS39340	COG5000	phosphorelay sensor kinase activity
MRAD2831_RS39345	COG2204	response regulator
MRAD2831_RS39350	COG1923	regulation of RNA biosynthetic process
MRAD2831_RS39355	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MRAD2831_RS39365	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
MRAD2831_RS39370	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MRAD2831_RS39370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MRAD2831_RS39380	COG4774	siderophore transport
MRAD2831_RS39395	COG0318	PFAM AMP-dependent synthetase and ligase
MRAD2831_RS39420	COG1686	Belongs to the peptidase S11 family
MRAD2831_RS39425	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MRAD2831_RS39455	COG0084	hydrolase, TatD family'
MRAD2831_RS39460	COG0321	lipoyl(octanoyl) transferase activity
MRAD2831_RS39460	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MRAD2831_RS39500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MRAD2831_RS39505	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MRAD2831_RS39515	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MRAD2831_RS39525	COG0151	Belongs to the GarS family
MRAD2831_RS39535	COG2140	Oxalate decarboxylase
MRAD2831_RS39545	COG4993	Dehydrogenase
MRAD2831_RS39555	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MRAD2831_RS39560	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MRAD2831_RS39565	COG2080	2 iron, 2 sulfur cluster binding
MRAD2831_RS39580	COG3920	Histidine kinase
MRAD2831_RS39590	COG2755	lipolytic protein G-D-S-L family
MRAD2831_RS39590	COG0657	acetylesterase activity
MRAD2831_RS39600	COG1061	Type III restriction enzyme res subunit
MRAD2831_RS39610	COG2423	ornithine cyclodeaminase activity
MRAD2831_RS39615	COG3616	Alanine racemase, N-terminal domain
MRAD2831_RS39640	COG0625	glutathione transferase activity
MRAD2831_RS39670	COG3920	Histidine kinase
MRAD2831_RS39685	COG0659	secondary active sulfate transmembrane transporter activity
MRAD2831_RS39710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MRAD2831_RS39720	COG0477	Major facilitator Superfamily
MRAD2831_RS39735	COG1733	regulation of RNA biosynthetic process
MRAD2831_RS39740	COG0604	alcohol dehydrogenase
MRAD2831_RS39750	COG2223	nitrite transmembrane transporter activity
MRAD2831_RS39755	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MRAD2831_RS39765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MRAD2831_RS39775	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MRAD2831_RS39780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MRAD2831_RS39785	COG0110	maltose O-acetyltransferase activity
MRAD2831_RS39815	COG2267	carboxylic ester hydrolase activity
MRAD2831_RS39820	COG0251	oxidation-reduction process
MRAD2831_RS39825	COG1335	isochorismatase
MRAD2831_RS39830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MRAD2831_RS39850	COG0612	Peptidase, M16
MRAD2831_RS39875	COG0058	SHG alpha-glucan phosphorylase activity
MRAD2831_RS39880	COG0366	Alpha amylase catalytic
MRAD2831_RS39885	COG0297	glycogen (starch) synthase activity
MRAD2831_RS39890	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MRAD2831_RS39895	COG0366	Alpha amylase catalytic
MRAD2831_RS39900	COG0366	Alpha amylase catalytic
MRAD2831_RS39910	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MRAD2831_RS39995	COG1914	H( )-stimulated, divalent metal cation uptake system
MRAD2831_RS40055	COG3956	TIGRFAM MazG family protein
MRAD2831_RS40095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MRAD2831_RS40115	COG1335	isochorismatase
MRAD2831_RS40125	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MRAD2831_RS40135	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MRAD2831_RS40140	COG2223	nitrite transmembrane transporter activity
MRAD2831_RS40150	COG2301	Belongs to the HpcH HpaI aldolase family
MRAD2831_RS40155	COG2852	Protein conserved in bacteria
MRAD2831_RS40160	COG4977	sequence-specific DNA binding
MRAD2831_RS40200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MRAD2831_RS40205	COG0596	Alpha beta hydrolase
MRAD2831_RS40210	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MRAD2831_RS40225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MRAD2831_RS40235	COG4957	zinc ion binding
MRAD2831_RS40290	COG1360	Flagellar Motor Protein
MRAD2831_RS40310	COG1338	Plays a role in the flagellum-specific transport system
MRAD2831_RS40320	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
MRAD2831_RS40330	COG1706	bacterial-type flagellum-dependent cell motility
MRAD2831_RS40340	COG4786	Flagellar basal body rod
MRAD2831_RS40345	COG1677	Flagellar hook-basal body complex protein FliE
MRAD2831_RS40350	COG1558	bacterial-type flagellum-dependent cell motility
MRAD2831_RS40355	COG1815	bacterial-type flagellum-dependent cell motility
MRAD2831_RS40395	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MRAD2831_RS40405	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
MRAD2831_RS40410	COG5443	negative regulation of bacterial-type flagellum assembly
MRAD2831_RS40430	COG1749	Flagellar hook protein flgE
MRAD2831_RS40435	COG1157	protein secretion by the type III secretion system
MRAD2831_RS40440	COG4786	Flagellar basal body rod
MRAD2831_RS40450	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MRAD2831_RS40465	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MRAD2831_RS40470	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MRAD2831_RS40475	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MRAD2831_RS40480	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MRAD2831_RS40485	COG0583	DNA-binding transcription factor activity
MRAD2831_RS40505	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS40545	COG0438	transferase activity, transferring glycosyl groups
MRAD2831_RS40545	COG1216	Glycosyl transferase, family 2
MRAD2831_RS40550	COG0477	Major facilitator Superfamily
MRAD2831_RS40555	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MRAD2831_RS40560	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MRAD2831_RS40565	COG1845	cytochrome c oxidase, subunit III
MRAD2831_RS40570	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MRAD2831_RS40590	COG0033	Phosphoglucomutase
MRAD2831_RS40600	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MRAD2831_RS40615	COG3585	molybdate ion transport
MRAD2831_RS40620	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MRAD2831_RS40630	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MRAD2831_RS40635	COG5001	Diguanylate cyclase
MRAD2831_RS40635	COG3300	MHYT domain
MRAD2831_RS40645	COG2205	protein histidine kinase activity
MRAD2831_RS40645	COG2202	Pas domain
MRAD2831_RS40660	COG1573	uracil-dna glycosylase
MRAD2831_RS40665	COG0284	orotidine-5'-phosphate decarboxylase activity
MRAD2831_RS40680	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS40710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MRAD2831_RS40715	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MRAD2831_RS40720	COG4521	taurine ABC transporter
MRAD2831_RS40735	COG3226	Transcriptional regulator
MRAD2831_RS40745	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MRAD2831_RS40765	COG0683	leucine binding
MRAD2831_RS40770	COG0583	DNA-binding transcription factor activity
MRAD2831_RS40780	COG2084	Dehydrogenase
MRAD2831_RS40785	COG2721	sulfolactate sulfo-lyase activity
MRAD2831_RS40810	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MRAD2831_RS40815	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MRAD2831_RS40820	COG1522	sequence-specific DNA binding
MRAD2831_RS40825	COG0175	sulfate reduction
MRAD2831_RS40830	COG0175	sulfate reduction
MRAD2831_RS40835	COG2895	sulfate adenylyltransferase (ATP) activity
MRAD2831_RS40845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MRAD2831_RS40850	COG0436	Aminotransferase
MRAD2831_RS40885	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MRAD2831_RS40890	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MRAD2831_RS40900	COG0612	Peptidase, M16
MRAD2831_RS40905	COG0612	Peptidase, M16
MRAD2831_RS40910	COG0346	lactoylglutathione lyase activity
MRAD2831_RS40925	COG2304	oxidoreductase activity
MRAD2831_RS40935	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MRAD2831_RS40940	COG0739	heme binding
MRAD2831_RS40960	COG1086	Polysaccharide biosynthesis protein
MRAD2831_RS40970	COG0683	leucine binding
MRAD2831_RS40985	COG1129	ABC transporter
MRAD2831_RS40990	COG1960	acyl-CoA dehydrogenase activity
MRAD2831_RS41000	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS41005	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS41010	COG0318	PFAM AMP-dependent synthetase and ligase
MRAD2831_RS41030	COG2124	cytochrome p450
MRAD2831_RS41050	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MRAD2831_RS41060	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
MRAD2831_RS41070	COG0156	8-amino-7-oxononanoate synthase activity
MRAD2831_RS41080	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MRAD2831_RS41105	COG2814	Major facilitator Superfamily
MRAD2831_RS41115	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
MRAD2831_RS41120	COG1429	ligase activity, forming nitrogen-metal bonds
MRAD2831_RS41125	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
MRAD2831_RS41130	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
MRAD2831_RS41150	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MRAD2831_RS41155	COG2211	Major facilitator Superfamily
MRAD2831_RS41160	COG0644	oxidoreductase
MRAD2831_RS41175	COG2010	Cytochrome c
MRAD2831_RS41175	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MRAD2831_RS41185	COG3034	peptidoglycan biosynthetic process
MRAD2831_RS41200	COG0825	malonyl-CoA metabolic process
MRAD2831_RS41245	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
MRAD2831_RS41250	COG0133	tryptophan synthase activity
MRAD2831_RS41255	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MRAD2831_RS41260	COG0287	Prephenate dehydrogenase
MRAD2831_RS41265	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MRAD2831_RS41280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MRAD2831_RS41285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MRAD2831_RS41285	COG2813	Specifically methylates the guanine in position
MRAD2831_RS41295	COG2895	sulfate adenylyltransferase (ATP) activity
MRAD2831_RS41295	COG0529	Catalyzes the synthesis of activated sulfate
MRAD2831_RS41325	COG0753	catalase activity
MRAD2831_RS41335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MRAD2831_RS41340	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MRAD2831_RS41360	COG1758	RNA polymerase activity
MRAD2831_RS41365	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MRAD2831_RS41375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MRAD2831_RS41380	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MRAD2831_RS41470	COG4957	zinc ion binding
MRAD2831_RS41505	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MRAD2831_RS41510	COG2084	Dehydrogenase
MRAD2831_RS41520	COG5265	(ABC) transporter
MRAD2831_RS41530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MRAD2831_RS41555	COG0583	DNA-binding transcription factor activity
MRAD2831_RS41560	COG0667	Aldo Keto reductase
MRAD2831_RS41570	COG3246	L-lysine catabolic process to acetate
MRAD2831_RS41580	COG1250	3-hydroxyacyl-CoA dehydrogenase
MRAD2831_RS41615	COG0633	Ferredoxin
MRAD2831_RS41640	COG2814	Major facilitator Superfamily
MRAD2831_RS41645	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MRAD2831_RS41650	COG1127	ABC transporter
MRAD2831_RS41655	COG3218	ABC-type transport auxiliary lipoprotein component
MRAD2831_RS41655	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MRAD2831_RS41665	COG2207	Transcriptional regulator
MRAD2831_RS41670	COG1396	sequence-specific DNA binding
MRAD2831_RS41675	COG0351	phosphomethylpyrimidine kinase
MRAD2831_RS41680	COG0352	thiamine-phosphate diphosphorylase activity
MRAD2831_RS41695	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MRAD2831_RS41720	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MRAD2831_RS41725	COG0720	synthase
MRAD2831_RS41730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MRAD2831_RS41740	COG0747	negative chemotaxis
MRAD2831_RS41745	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MRAD2831_RS41750	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
MRAD2831_RS41765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MRAD2831_RS41770	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MRAD2831_RS41775	COG1360	Flagellar Motor Protein
MRAD2831_RS41865	COG0582	viral genome integration into host DNA
MRAD2831_RS41870	COG0840	transmembrane signaling receptor activity
MRAD2831_RS41875	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS41890	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MRAD2831_RS41900	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MRAD2831_RS41905	COG3023	N-Acetylmuramoyl-L-alanine amidase
MRAD2831_RS41915	COG0477	Major facilitator Superfamily
MRAD2831_RS41920	COG0493	'glutamate synthase
MRAD2831_RS41970	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MRAD2831_RS41980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MRAD2831_RS41985	COG0372	Belongs to the citrate synthase family
MRAD2831_RS42000	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MRAD2831_RS42005	COG1381	Involved in DNA repair and RecF pathway recombination
MRAD2831_RS42015	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
MRAD2831_RS42025	COG1914	H( )-stimulated, divalent metal cation uptake system
MRAD2831_RS42035	COG1819	glycosyl
MRAD2831_RS42045	COG1136	(ABC) transporter
MRAD2831_RS42050	COG4591	ABC-type transport system involved in lipoprotein release permease component
MRAD2831_RS42055	COG0442	prolyl-tRNA aminoacylation
MRAD2831_RS42065	COG0346	lactoylglutathione lyase activity
MRAD2831_RS42080	COG1007	ATP synthesis coupled electron transport
MRAD2831_RS42095	COG0713	ATP synthesis coupled electron transport
MRAD2831_RS42105	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MRAD2831_RS42110	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MRAD2831_RS42125	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MRAD2831_RS42135	COG0649	NAD binding
MRAD2831_RS42140	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MRAD2831_RS42145	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MRAD2831_RS42150	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MRAD2831_RS42160	COG0697	spore germination
MRAD2831_RS42170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MRAD2831_RS42195	COG1132	(ABC) transporter
MRAD2831_RS42235	COG3546	catalase activity
MRAD2831_RS42300	COG2183	response to ionizing radiation
MRAD2831_RS42310	COG3920	Histidine kinase
MRAD2831_RS42310	COG2202	Pas domain
MRAD2831_RS42320	COG0242	peptide deformylase activity
MRAD2831_RS42325	COG1595	DNA-templated transcription, initiation
MRAD2831_RS42335	COG0488	(ABC) transporter
MRAD2831_RS42370	COG2814	Major facilitator Superfamily
MRAD2831_RS42390	COG1858	cytochrome C peroxidase
MRAD2831_RS42400	COG4191	Histidine kinase
MRAD2831_RS42400	COG0784	Response regulator, receiver
MRAD2831_RS42405	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS42425	COG4651	solute:proton antiporter activity
MRAD2831_RS42425	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MRAD2831_RS42435	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MRAD2831_RS42455	COG0028	Belongs to the TPP enzyme family
MRAD2831_RS42465	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MRAD2831_RS42485	COG1410	methionine synthase
MRAD2831_RS42485	COG0646	methionine synthase
MRAD2831_RS42495	COG2226	methyltransferase
MRAD2831_RS42500	COG0406	alpha-ribazole phosphatase activity
MRAD2831_RS42505	COG3781	membrane
MRAD2831_RS42510	COG1940	carbohydrate kinase activity
MRAD2831_RS42515	COG1301	dicarboxylic acid transport
MRAD2831_RS42525	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MRAD2831_RS42550	COG3768	UPF0283 membrane protein
MRAD2831_RS42555	COG3106	COG3106 Predicted ATPase
MRAD2831_RS42565	COG0483	inositol monophosphate 1-phosphatase activity
MRAD2831_RS42570	COG0628	permease
MRAD2831_RS42595	COG0489	protein tyrosine kinase activity
MRAD2831_RS42600	COG0746	molybdenum cofactor guanylyltransferase activity
MRAD2831_RS42620	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MRAD2831_RS42625	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MRAD2831_RS42650	COG3191	aminopeptidase activity
MRAD2831_RS42665	COG0784	Response regulator, receiver
MRAD2831_RS42665	COG2205	protein histidine kinase activity
MRAD2831_RS42670	COG2962	Rard protein
MRAD2831_RS42675	COG0259	pyridoxamine-phosphate oxidase activity
MRAD2831_RS42685	COG0463	Glycosyl transferase, family 2
MRAD2831_RS42695	COG0626	cystathionine gamma-synthase activity
MRAD2831_RS42705	COG2204	response regulator
MRAD2831_RS42715	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MRAD2831_RS42720	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MRAD2831_RS42720	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MRAD2831_RS42740	COG2867	negative regulation of translational initiation
MRAD2831_RS42745	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MRAD2831_RS42750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MRAD2831_RS42755	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MRAD2831_RS42775	COG0835	chemotaxis
MRAD2831_RS42805	COG4191	Histidine kinase
MRAD2831_RS42815	COG0203	ribosomal protein L17
MRAD2831_RS42820	COG0202	RNA polymerase activity
MRAD2831_RS42830	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MRAD2831_RS42835	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MRAD2831_RS42850	COG0563	adenylate kinase activity
MRAD2831_RS42855	COG0201	protein transport
MRAD2831_RS42860	COG0200	Binds to the 23S rRNA
MRAD2831_RS42865	COG1841	ribosomal large subunit assembly
MRAD2831_RS42870	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MRAD2831_RS42875	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MRAD2831_RS42880	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MRAD2831_RS42885	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MRAD2831_RS42890	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MRAD2831_RS42895	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MRAD2831_RS42900	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MRAD2831_RS42905	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MRAD2831_RS42915	COG0765	amino acid transport
MRAD2831_RS42920	COG0765	amino acid transport
MRAD2831_RS42925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MRAD2831_RS42930	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MRAD2831_RS42935	COG0049	tRNA binding
MRAD2831_RS42940	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MRAD2831_RS42945	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MRAD2831_RS42950	COG0051	transcription antitermination factor activity, RNA binding
MRAD2831_RS42955	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MRAD2831_RS42960	COG0088	Forms part of the polypeptide exit tunnel
MRAD2831_RS42965	COG0089	rRNA binding
MRAD2831_RS42970	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MRAD2831_RS42975	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MRAD2831_RS42980	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MRAD2831_RS42985	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MRAD2831_RS42990	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MRAD2831_RS42995	COG0255	Belongs to the universal ribosomal protein uL29 family
MRAD2831_RS43000	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MRAD2831_RS43005	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MRAD2831_RS43015	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MRAD2831_RS43020	COG1684	flagellar biosynthetic protein fliR
MRAD2831_RS43025	COG1987	bacterial-type flagellum assembly
MRAD2831_RS43030	COG1677	Flagellar hook-basal body complex protein FliE
MRAD2831_RS43035	COG1558	bacterial-type flagellum-dependent cell motility
MRAD2831_RS43040	COG1815	bacterial-type flagellum-dependent cell motility
MRAD2831_RS43055	COG0477	Major facilitator Superfamily
MRAD2831_RS43065	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MRAD2831_RS43095	COG3683	transport system, periplasmic component
MRAD2831_RS43100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MRAD2831_RS43135	COG0683	leucine binding
MRAD2831_RS43145	COG0765	amino acid transport
MRAD2831_RS43150	COG0765	amino acid transport
MRAD2831_RS43155	COG1126	abc transporter atp-binding protein
MRAD2831_RS43165	COG0314	molybdopterin synthase activity
MRAD2831_RS43175	COG0154	amidase activity
MRAD2831_RS43195	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MRAD2831_RS43230	COG0596	Alpha beta hydrolase
MRAD2831_RS43235	COG1862	Preprotein translocase
MRAD2831_RS43240	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MRAD2831_RS43250	COG3737	Protein of unknown function (DUF498/DUF598)
MRAD2831_RS43260	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MRAD2831_RS43265	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MRAD2831_RS43305	COG1051	belongs to the nudix hydrolase family
MRAD2831_RS43310	COG0288	reversible hydration of carbon dioxide
MRAD2831_RS43320	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MRAD2831_RS43340	COG2816	NAD+ diphosphatase activity
MRAD2831_RS43345	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MRAD2831_RS43345	COG1648	precorrin-2 dehydrogenase activity
MRAD2831_RS43350	COG0243	molybdopterin cofactor binding
MRAD2831_RS43360	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MRAD2831_RS43365	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MRAD2831_RS43380	COG3707	response regulator
MRAD2831_RS43390	COG3387	PFAM Glycoside hydrolase 15-related
MRAD2831_RS43400	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MRAD2831_RS43405	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
MRAD2831_RS43410	COG0363	glucosamine-6-phosphate deaminase activity
MRAD2831_RS43420	COG1522	sequence-specific DNA binding
MRAD2831_RS43425	COG0717	Belongs to the dCTP deaminase family
MRAD2831_RS43430	COG2967	ApaG domain
MRAD2831_RS43435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MRAD2831_RS43440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MRAD2831_RS43455	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MRAD2831_RS43460	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MRAD2831_RS43485	COG1473	amidohydrolase
MRAD2831_RS43505	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MRAD2831_RS43515	COG4149	molybdate abc transporter
MRAD2831_RS43520	COG0725	ABC transporter, periplasmic molybdate-binding protein
MRAD2831_RS43530	COG2264	protein methyltransferase activity
MRAD2831_RS43545	COG0006	proline dipeptidase activity
MRAD2831_RS43545	COG0006	proline dipeptidase activity
MRAD2831_RS43555	COG0745	RESPONSE REGULATOR receiver
MRAD2831_RS43560	COG0704	Plays a role in the regulation of phosphate uptake
MRAD2831_RS43565	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MRAD2831_RS43570	COG0581	inorganic phosphate transmembrane transporter activity
MRAD2831_RS43600	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MRAD2831_RS43610	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MRAD2831_RS43615	COG0849	cell division
MRAD2831_RS43620	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MRAD2831_RS43625	COG1181	Belongs to the D-alanine--D-alanine ligase family
MRAD2831_RS43630	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MRAD2831_RS43635	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MRAD2831_RS43640	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MRAD2831_RS43660	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MRAD2831_RS43665	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MRAD2831_RS43670	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MRAD2831_RS43685	COG0275	rRNA processing
MRAD2831_RS43695	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MRAD2831_RS43700	COG0308	aminopeptidase N
MRAD2831_RS43705	COG2202	Pas domain
MRAD2831_RS43705	COG2205	protein histidine kinase activity
MRAD2831_RS43750	COG1091	dTDP-4-dehydrorhamnose reductase activity
MRAD2831_RS43755	COG1088	dTDP-glucose 4,6-dehydratase activity
MRAD2831_RS43760	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
MRAD2831_RS43775	COG0602	queuosine metabolic process
MRAD2831_RS43780	COG1686	Belongs to the peptidase S11 family
MRAD2831_RS43785	COG0523	cobalamin synthesis protein
MRAD2831_RS43795	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MRAD2831_RS43800	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MRAD2831_RS43810	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MRAD2831_RS43845	COG1196	nuclear chromosome segregation
MRAD2831_RS43845	COG0741	lytic transglycosylase activity
MRAD2831_RS43845	COG0739	heme binding
MRAD2831_RS43850	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MRAD2831_RS43860	COG2205	protein histidine kinase activity
MRAD2831_RS43860	COG0784	Response regulator, receiver
MRAD2831_RS43860	COG5002	protein histidine kinase activity
MRAD2831_RS43870	COG0583	DNA-binding transcription factor activity
MRAD2831_RS43885	COG1454	alcohol dehydrogenase
MRAD2831_RS43900	COG3243	poly(R)-hydroxyalkanoic acid synthase
MRAD2831_RS43920	COG1566	PFAM secretion protein HlyD family protein
MRAD2831_RS43930	COG1289	transmembrane transporter activity
MRAD2831_RS43990	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MRAD2831_RS43995	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MRAD2831_RS44000	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MRAD2831_RS44025	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
MRAD2831_RS44035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MRAD2831_RS44040	COG5001	Diguanylate cyclase
MRAD2831_RS44045	COG1396	sequence-specific DNA binding
MRAD2831_RS44060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MRAD2831_RS44075	COG0438	transferase activity, transferring glycosyl groups
MRAD2831_RS44080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MRAD2831_RS44115	COG0135	phosphoribosylanthranilate isomerase activity
MRAD2831_RS44125	COG0776	regulation of translation
MRAD2831_RS44130	COG0616	signal peptide processing
MRAD2831_RS44135	COG0539	negative regulation of cytoplasmic translation
MRAD2831_RS44140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MRAD2831_RS44150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MRAD2831_RS44200	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS44250	COG0829	nickel cation binding
MRAD2831_RS44260	COG0840	transmembrane signaling receptor activity
MRAD2831_RS44280	COG3387	PFAM Glycoside hydrolase 15-related
MRAD2831_RS44285	COG4638	Rieske (2fe-2S)
MRAD2831_RS44290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MRAD2831_RS44290	COG1017	nitric oxide dioxygenase activity
MRAD2831_RS44295	COG1902	pentaerythritol trinitrate reductase activity
MRAD2831_RS44295	COG0446	pyridine nucleotide-disulphide oxidoreductase
MRAD2831_RS44300	COG2181	nitrate reductase activity
MRAD2831_RS44300	COG0247	lactate metabolic process
MRAD2831_RS44320	COG1760	l-serine dehydratase
MRAD2831_RS44330	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MRAD2831_RS44330	COG0446	pyridine nucleotide-disulphide oxidoreductase
MRAD2831_RS44365	COG4175	Glycine betaine
MRAD2831_RS44365	COG0517	IMP dehydrogenase activity
MRAD2831_RS44400	COG4191	Histidine kinase
MRAD2831_RS44400	COG0784	Response regulator, receiver
MRAD2831_RS44535	COG0798	PFAM Bile acid sodium symporter
MRAD2831_RS44540	COG3177	Filamentation induced by cAMP protein fic
MRAD2831_RS44615	COG2186	Transcriptional regulator
MRAD2831_RS44645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MRAD2831_RS44650	COG2226	methyltransferase
MRAD2831_RS44750	COG2801	Transposase and inactivated derivatives
MRAD2831_RS44780	COG4191	Histidine kinase
MRAD2831_RS44785	COG4566	intracellular signal transduction
MRAD2831_RS44790	COG4566	intracellular signal transduction
MRAD2831_RS44795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MRAD2831_RS44800	COG0303	'Molybdopterin
MRAD2831_RS44805	COG0521	Mo-molybdopterin cofactor biosynthetic process
MRAD2831_RS44810	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MRAD2831_RS44820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MRAD2831_RS44825	COG2181	nitrate reductase activity
MRAD2831_RS44830	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
MRAD2831_RS44835	COG1140	nitrate reductase beta subunit
MRAD2831_RS44840	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MRAD2831_RS44880	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MRAD2831_RS44925	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MRAD2831_RS44930	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
MRAD2831_RS45050	COG2801	Transposase and inactivated derivatives
MRAD2831_RS45215	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MRAD2831_RS45225	COG0288	reversible hydration of carbon dioxide
MRAD2831_RS45230	COG0473	3-isopropylmalate dehydrogenase activity
MRAD2831_RS45235	COG2226	methyltransferase
MRAD2831_RS45240	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MRAD2831_RS45245	COG0784	Response regulator, receiver
MRAD2831_RS45245	COG2205	protein histidine kinase activity
MRAD2831_RS45250	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MRAD2831_RS45260	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MRAD2831_RS45270	COG2226	methyltransferase
MRAD2831_RS45295	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MRAD2831_RS45305	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MRAD2831_RS45345	COG5001	Diguanylate cyclase
MRAD2831_RS45350	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
MRAD2831_RS45375	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MRAD2831_RS45385	COG0546	phosphoglycolate phosphatase activity
MRAD2831_RS45390	COG0436	Aminotransferase
MRAD2831_RS45400	COG0511	ligase activity, forming carbon-carbon bonds
MRAD2831_RS45405	COG0439	Biotin carboxylase
MRAD2831_RS45410	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MRAD2831_RS45425	COG1612	heme a metabolic process
MRAD2831_RS45430	COG1272	protein, Hemolysin III
MRAD2831_RS45435	COG0297	glycogen (starch) synthase activity
MRAD2831_RS45465	COG1131	(ABC) transporter
MRAD2831_RS45545	COG0412	Dienelactone hydrolase
MRAD2831_RS45560	COG1278	Cold shock
MRAD2831_RS45570	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MRAD2831_RS45575	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
MRAD2831_RS45580	COG1509	lysine 2,3-aminomutase activity
MRAD2831_RS45585	COG0625	glutathione transferase activity
MRAD2831_RS45595	COG1434	Gram-negative-bacterium-type cell wall biogenesis
MRAD2831_RS45610	COG1254	Belongs to the acylphosphatase family
MRAD2831_RS45630	COG4770	biotin carboxylase activity
MRAD2831_RS45640	COG1376	ErfK ybiS ycfS ynhG family protein
MRAD2831_RS45645	COG0123	including yeast histone deacetylase and acetoin utilization protein
MRAD2831_RS45655	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MRAD2831_RS45655	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MRAD2831_RS45660	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MRAD2831_RS45670	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MRAD2831_RS45675	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MRAD2831_RS45685	COG0805	protein transport
MRAD2831_RS45690	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MRAD2831_RS45695	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MRAD2831_RS45700	COG1472	Belongs to the glycosyl hydrolase 3 family
MRAD2831_RS45710	COG0018	arginyl-trna synthetase
MRAD2831_RS45720	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MRAD2831_RS45725	COG0316	Belongs to the HesB IscA family
MRAD2831_RS45740	COG2814	Major facilitator Superfamily
MRAD2831_RS45750	COG1116	anion transmembrane transporter activity
MRAD2831_RS45765	COG2154	pterin-4-alpha-carbinolamine dehydratase
MRAD2831_RS45775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MRAD2831_RS45785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MRAD2831_RS45795	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
MRAD2831_RS45800	COG0784	Response regulator, receiver
MRAD2831_RS45820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MRAD2831_RS45825	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MRAD2831_RS45830	COG0235	Class ii aldolase
MRAD2831_RS45840	COG1802	Transcriptional regulator
MRAD2831_RS45855	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MRAD2831_RS45880	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MRAD2831_RS45895	COG2989	Protein conserved in bacteria
MRAD2831_RS45910	COG0574	Belongs to the PEP-utilizing enzyme family
MRAD2831_RS45910	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MRAD2831_RS45945	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
MRAD2831_RS45950	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
MRAD2831_RS45955	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
MRAD2831_RS45960	COG1063	alcohol dehydrogenase
MRAD2831_RS45965	COG0500	methyltransferase
MRAD2831_RS45970	COG0142	geranyltranstransferase activity
MRAD2831_RS45995	COG0438	transferase activity, transferring glycosyl groups
MRAD2831_RS46000	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MRAD2831_RS46015	COG0747	negative chemotaxis
MRAD2831_RS46020	COG0601	transmembrane transport
MRAD2831_RS46025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MRAD2831_RS46030	COG2202	Pas domain
MRAD2831_RS46030	COG3920	Histidine kinase
MRAD2831_RS46045	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MRAD2831_RS46065	COG0181	hydroxymethylbilane synthase activity
MRAD2831_RS46075	COG1562	ergosterol biosynthetic process
MRAD2831_RS46080	COG1233	COG1233 Phytoene dehydrogenase and related
MRAD2831_RS46090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MRAD2831_RS46105	COG0129	dihydroxy-acid dehydratase activity
MRAD2831_RS46110	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MRAD2831_RS46115	COG1764	response to oxidative stress
MRAD2831_RS46120	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
MRAD2831_RS46180	COG0832	Belongs to the urease beta subunit family
MRAD2831_RS46180	COG0831	urea catabolic process
MRAD2831_RS46185	COG0804	urea catabolic process
MRAD2831_RS46190	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MRAD2831_RS46195	COG0830	nickel cation binding
MRAD2831_RS46200	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MRAD2831_RS46215	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MRAD2831_RS46220	COG1177	transmembrane transport
MRAD2831_RS46225	COG1176	ABC-type spermidine putrescine transport system, permease component I
MRAD2831_RS46230	COG3842	ATPase activity
MRAD2831_RS46240	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MRAD2831_RS46245	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MRAD2831_RS46245	COG2199	diguanylate cyclase activity
MRAD2831_RS46250	COG0488	(ABC) transporter
MRAD2831_RS46255	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MRAD2831_RS46260	COG0583	DNA-binding transcription factor activity
MRAD2831_RS46290	COG4166	transmembrane transport
MRAD2831_RS46305	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MRAD2831_RS46315	COG0395	ABC-type sugar transport system, permease component
MRAD2831_RS46320	COG1175	transmembrane transport
MRAD2831_RS46330	COG3842	ATPase activity
MRAD2831_RS46340	COG0277	FAD linked oxidase domain protein
MRAD2831_RS46350	COG3246	L-lysine catabolic process to acetate
MRAD2831_RS46355	COG1250	3-hydroxyacyl-CoA dehydrogenase
MRAD2831_RS46375	COG1802	Transcriptional regulator
MRAD2831_RS46380	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS46385	COG0129	dihydroxy-acid dehydratase activity
MRAD2831_RS46390	COG0277	FAD linked oxidase domain protein
MRAD2831_RS46390	COG0247	lactate metabolic process
MRAD2831_RS46395	COG1802	Transcriptional regulator
MRAD2831_RS46405	COG1802	Transcriptional regulator
MRAD2831_RS46410	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MRAD2831_RS46430	COG1024	Enoyl-CoA hydratase
MRAD2831_RS46440	COG2271	Major facilitator Superfamily
MRAD2831_RS46445	COG2223	nitrite transmembrane transporter activity
MRAD2831_RS46450	COG1388	LysM domain
MRAD2831_RS46450	COG1376	ErfK ybiS ycfS ynhG family protein
MRAD2831_RS46455	COG1494	fructose-1,6-bisphosphatase
MRAD2831_RS46470	COG0708	Exodeoxyribonuclease III
MRAD2831_RS46485	COG0129	dihydroxy-acid dehydratase activity
MRAD2831_RS46495	COG2801	Transposase and inactivated derivatives
MRAD2831_RS46510	COG1139	Iron-sulfur cluster binding protein
MRAD2831_RS46515	COG0247	lactate metabolic process
MRAD2831_RS46550	COG1376	ErfK ybiS ycfS ynhG family protein
MRAD2831_RS46560	COG0792	nuclease activity
MRAD2831_RS46565	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MRAD2831_RS46575	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MRAD2831_RS46580	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MRAD2831_RS46585	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MRAD2831_RS46600	COG0477	Major facilitator Superfamily
MRAD2831_RS46610	COG3750	Belongs to the UPF0335 family
MRAD2831_RS46615	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MRAD2831_RS46630	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MRAD2831_RS46635	COG0424	maF-like protein
MRAD2831_RS46675	COG2086	electron transfer activity
MRAD2831_RS46680	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MRAD2831_RS46685	COG1250	3-hydroxyacyl-CoA dehydrogenase
MRAD2831_RS46695	COG0604	alcohol dehydrogenase
MRAD2831_RS46695	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS46695	COG3321	synthase
MRAD2831_RS46710	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
MRAD2831_RS46715	COG4251	negative regulation of phosphorylation
MRAD2831_RS46720	COG4251	negative regulation of phosphorylation
MRAD2831_RS46730	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MRAD2831_RS46735	COG0840	transmembrane signaling receptor activity
MRAD2831_RS46745	COG1309	transcriptional regulator
MRAD2831_RS46775	COG2884	Cell division ATP-binding protein ftsE
MRAD2831_RS46795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MRAD2831_RS46800	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MRAD2831_RS46805	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
MRAD2831_RS46825	COG2183	response to ionizing radiation
MRAD2831_RS46865	COG0583	DNA-binding transcription factor activity
MRAD2831_RS46870	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS46875	COG3959	Transketolase, thiamine diphosphate binding domain
MRAD2831_RS46880	COG3958	Transketolase
MRAD2831_RS46885	COG2084	Dehydrogenase
MRAD2831_RS46900	COG0318	PFAM AMP-dependent synthetase and ligase
MRAD2831_RS46905	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MRAD2831_RS46910	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
MRAD2831_RS46915	COG3257	ureidoglycine aminohydrolase activity
MRAD2831_RS46920	COG1301	dicarboxylic acid transport
MRAD2831_RS46925	COG0583	DNA-binding transcription factor activity
MRAD2831_RS46930	COG0824	Thioesterase
MRAD2831_RS46935	COG5001	Diguanylate cyclase
MRAD2831_RS46975	COG4191	Histidine kinase
MRAD2831_RS46975	COG0784	Response regulator, receiver
MRAD2831_RS46985	COG0393	Putative heavy-metal-binding
MRAD2831_RS47080	COG2197	response regulator
MRAD2831_RS47085	COG2354	Protein conserved in bacteria
MRAD2831_RS47095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MRAD2831_RS47100	COG1309	transcriptional regulator
MRAD2831_RS47110	COG3920	Histidine kinase
MRAD2831_RS47110	COG2202	Pas domain
MRAD2831_RS47120	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MRAD2831_RS47130	COG1051	belongs to the nudix hydrolase family
MRAD2831_RS47140	COG0277	FAD linked oxidase domain protein
MRAD2831_RS47150	COG0747	negative chemotaxis
MRAD2831_RS47155	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MRAD2831_RS47155	COG0506	proline dehydrogenase activity
MRAD2831_RS47155	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MRAD2831_RS47170	COG2721	sulfolactate sulfo-lyase activity
MRAD2831_RS47175	COG2271	Major facilitator Superfamily
MRAD2831_RS47180	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MRAD2831_RS47210	COG3321	synthase
MRAD2831_RS47210	COG0604	alcohol dehydrogenase
MRAD2831_RS47210	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS47220	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS47225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MRAD2831_RS47240	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MRAD2831_RS47245	COG3025	triphosphatase activity
MRAD2831_RS47265	COG0438	transferase activity, transferring glycosyl groups
MRAD2831_RS47275	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MRAD2831_RS47290	COG0659	secondary active sulfate transmembrane transporter activity
MRAD2831_RS47295	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MRAD2831_RS47300	COG5006	permease, DMT superfamily
MRAD2831_RS47305	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MRAD2831_RS47305	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
MRAD2831_RS47315	COG2205	protein histidine kinase activity
MRAD2831_RS47320	COG0745	RESPONSE REGULATOR receiver
MRAD2831_RS47335	COG0481	GTPase activity
MRAD2831_RS47360	COG0303	'Molybdopterin
MRAD2831_RS47365	COG0315	cyclic pyranopterin monophosphate synthase activity
MRAD2831_RS47370	COG0134	indole-3-glycerol-phosphate synthase activity
MRAD2831_RS47375	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MRAD2831_RS47385	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MRAD2831_RS47390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MRAD2831_RS47395	COG0149	triose-phosphate isomerase activity
MRAD2831_RS47410	COG0504	CTP synthase activity
MRAD2831_RS47490	COG2875	Belongs to the precorrin methyltransferase family
MRAD2831_RS47495	COG1797	cobyrinic acid a,c-diamide synthase activity
MRAD2831_RS47500	COG1396	sequence-specific DNA binding
MRAD2831_RS47510	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MRAD2831_RS47515	COG0735	belongs to the Fur family
MRAD2831_RS47535	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MRAD2831_RS47545	COG1968	undecaprenyl-diphosphatase activity
MRAD2831_RS47575	COG0606	chelatase, subunit chli
MRAD2831_RS47585	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MRAD2831_RS47595	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MRAD2831_RS47600	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MRAD2831_RS47605	COG0242	peptide deformylase activity
MRAD2831_RS47610	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MRAD2831_RS47615	COG0101	tRNA pseudouridine synthase activity
MRAD2831_RS47620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MRAD2831_RS47630	COG0438	transferase activity, transferring glycosyl groups
MRAD2831_RS47635	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MRAD2831_RS47640	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MRAD2831_RS47645	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MRAD2831_RS47650	COG0072	phenylalanine-tRNA ligase activity
MRAD2831_RS47650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MRAD2831_RS47655	COG0653	protein targeting
MRAD2831_RS47665	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MRAD2831_RS47670	COG0438	transferase activity, transferring glycosyl groups
MRAD2831_RS47685	COG0071	Belongs to the small heat shock protein (HSP20) family
MRAD2831_RS47705	COG0848	biopolymer transport protein
MRAD2831_RS47725	COG1671	Belongs to the UPF0178 family
MRAD2831_RS47735	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
MRAD2831_RS47740	COG0656	L-ascorbic acid biosynthetic process
MRAD2831_RS47755	COG0583	DNA-binding transcription factor activity
MRAD2831_RS47790	COG1403	HNH endonuclease
MRAD2831_RS47800	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MRAD2831_RS47820	COG0367	asparagine synthase
MRAD2831_RS47830	COG0024	Methionine aminopeptidase
MRAD2831_RS47890	COG3383	formate dehydrogenase (NAD+) activity
MRAD2831_RS47890	COG0243	molybdopterin cofactor binding
MRAD2831_RS47895	COG0437	4 iron, 4 sulfur cluster binding
MRAD2831_RS47900	COG2864	formate dehydrogenase
MRAD2831_RS47910	COG0784	Response regulator, receiver
MRAD2831_RS47910	COG5002	protein histidine kinase activity
MRAD2831_RS47915	COG0784	Response regulator, receiver
MRAD2831_RS47915	COG4191	Histidine kinase
MRAD2831_RS47920	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MRAD2831_RS47945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MRAD2831_RS47950	COG4172	Belongs to the ABC transporter superfamily
MRAD2831_RS47955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MRAD2831_RS47960	COG0601	transmembrane transport
MRAD2831_RS47965	COG0747	negative chemotaxis
MRAD2831_RS47985	COG0583	DNA-binding transcription factor activity
MRAD2831_RS48005	COG3842	ATPase activity
MRAD2831_RS48025	COG4774	siderophore transport
MRAD2831_RS48045	COG0243	molybdopterin cofactor binding
MRAD2831_RS48060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MRAD2831_RS48065	COG0601	transmembrane transport
MRAD2831_RS48075	COG4172	Belongs to the ABC transporter superfamily
MRAD2831_RS48090	COG2188	Transcriptional regulator
MRAD2831_RS48110	COG0477	Major facilitator Superfamily
MRAD2831_RS48125	COG2084	Dehydrogenase
MRAD2831_RS48155	COG1960	acyl-CoA dehydrogenase activity
MRAD2831_RS48165	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MRAD2831_RS48170	COG1024	Enoyl-CoA hydratase
MRAD2831_RS48195	COG2271	Major facilitator Superfamily
MRAD2831_RS48215	COG4191	Histidine kinase
MRAD2831_RS48215	COG0784	Response regulator, receiver
MRAD2831_RS48220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MRAD2831_RS48225	COG4191	Histidine kinase
MRAD2831_RS48230	COG4566	intracellular signal transduction
MRAD2831_RS48235	COG4566	intracellular signal transduction
MRAD2831_RS48240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MRAD2831_RS48245	COG2837	iron assimilation
MRAD2831_RS48250	COG2822	iron ion transport
MRAD2831_RS48260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MRAD2831_RS48260	COG4191	Histidine kinase
MRAD2831_RS48270	COG0747	negative chemotaxis
MRAD2831_RS48295	COG3437	response regulator, receiver
MRAD2831_RS48295	COG0784	Response regulator, receiver
MRAD2831_RS48300	COG3474	cytochrome
MRAD2831_RS48305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MRAD2831_RS48320	COG4957	zinc ion binding
MRAD2831_RS48340	COG5001	Diguanylate cyclase
MRAD2831_RS48345	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MRAD2831_RS48355	COG1802	Transcriptional regulator
MRAD2831_RS48375	COG1129	ABC transporter
MRAD2831_RS48390	COG4160	amino acid transport
MRAD2831_RS48400	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
MRAD2831_RS48410	COG4977	sequence-specific DNA binding
MRAD2831_RS48415	COG4302	ethanolamine ammonia-lyase activity
MRAD2831_RS48445	COG1129	ABC transporter
MRAD2831_RS48475	COG0625	glutathione transferase activity
MRAD2831_RS48480	COG1017	nitric oxide dioxygenase activity
MRAD2831_RS48480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MRAD2831_RS48510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MRAD2831_RS48530	COG1252	NADH dehydrogenase
MRAD2831_RS48540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MRAD2831_RS48545	COG1116	anion transmembrane transporter activity
MRAD2831_RS48565	COG3307	-O-antigen
MRAD2831_RS48570	COG3306	glycosyltransferase involved in LPS biosynthesis
MRAD2831_RS48585	COG1215	transferase activity, transferring glycosyl groups
MRAD2831_RS48595	COG0583	DNA-binding transcription factor activity
MRAD2831_RS48600	COG4336	lyase activity
MRAD2831_RS48605	COG2814	Major facilitator Superfamily
MRAD2831_RS48610	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MRAD2831_RS48620	COG1984	allophanate hydrolase subunit 2
MRAD2831_RS48625	COG0235	Class ii aldolase
MRAD2831_RS48630	COG2951	lytic endotransglycosylase activity
MRAD2831_RS48660	COG2358	TRAP transporter, solute receptor (TAXI family
MRAD2831_RS48665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MRAD2831_RS48690	COG1217	gtp-binding protein TYPA
MRAD2831_RS48700	COG2124	cytochrome p450
MRAD2831_RS48710	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MRAD2831_RS48715	COG2894	cell division
MRAD2831_RS48720	COG0850	regulation of cytokinetic process
MRAD2831_RS48725	COG0850	regulation of cytokinetic process
MRAD2831_RS48730	COG1074	ATP-dependent DNA helicase activity
MRAD2831_RS48740	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MRAD2831_RS48745	COG0285	dihydrofolate synthase activity
MRAD2831_RS48750	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MRAD2831_RS48755	COG0159	tryptophan synthase activity
MRAD2831_RS48760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MRAD2831_RS48775	COG4957	zinc ion binding
MRAD2831_RS48790	COG1380	Effector of murein hydrolase LrgA
MRAD2831_RS48815	COG4585	Histidine kinase
MRAD2831_RS48825	COG0513	Belongs to the DEAD box helicase family
MRAD2831_RS48830	COG0387	Pfam Sodium calcium exchanger
MRAD2831_RS48840	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MRAD2831_RS48855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MRAD2831_RS48880	COG3622	Belongs to the hyi family
MRAD2831_RS48890	COG1609	Transcriptional regulator
MRAD2831_RS48900	COG2706	6-phosphogluconolactonase activity
MRAD2831_RS48905	COG2271	Major facilitator Superfamily
MRAD2831_RS48910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MRAD2831_RS48925	COG2202	Pas domain
MRAD2831_RS48925	COG3920	Histidine kinase
MRAD2831_RS48935	COG5265	(ABC) transporter
MRAD2831_RS48960	COG2205	protein histidine kinase activity
MRAD2831_RS48985	COG0129	dihydroxy-acid dehydratase activity
MRAD2831_RS48990	COG0800	Aldolase
MRAD2831_RS49015	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MRAD2831_RS49025	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MRAD2831_RS49030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MRAD2831_RS49035	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MRAD2831_RS49040	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MRAD2831_RS49045	COG0750	zinc metalloprotease
MRAD2831_RS49060	COG1309	transcriptional regulator
MRAD2831_RS49065	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MRAD2831_RS49075	COG0233	cytoplasmic translational termination
MRAD2831_RS49080	COG0528	UMP kinase activity
MRAD2831_RS49085	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MRAD2831_RS49090	COG0052	Belongs to the universal ribosomal protein uS2 family
MRAD2831_RS49100	COG1187	pseudouridine synthase activity
MRAD2831_RS49105	COG2813	Specifically methylates the guanine in position
MRAD2831_RS49110	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MRAD2831_RS49115	COG0571	ribonuclease III activity
MRAD2831_RS49120	COG0681	Belongs to the peptidase S26 family
MRAD2831_RS49125	COG0736	holo-[acyl-carrier-protein] synthase activity
MRAD2831_RS49130	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MRAD2831_RS49135	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MRAD2831_RS49180	COG3608	succinylglutamate desuccinylase aspartoacylase
MRAD2831_RS49180	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MRAD2831_RS49215	COG2979	Protein of unknown function (DUF533)
MRAD2831_RS49235	COG1703	isobutyryl-CoA mutase activity
MRAD2831_RS49245	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS49250	COG2205	protein histidine kinase activity
MRAD2831_RS49255	COG0745	RESPONSE REGULATOR receiver
MRAD2831_RS49290	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MRAD2831_RS49295	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MRAD2831_RS49300	COG1216	Glycosyl transferase, family 2
MRAD2831_RS49300	COG0438	transferase activity, transferring glycosyl groups
MRAD2831_RS49305	COG0438	transferase activity, transferring glycosyl groups
MRAD2831_RS49305	COG1216	Glycosyl transferase, family 2
MRAD2831_RS49345	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MRAD2831_RS49350	COG0583	DNA-binding transcription factor activity
MRAD2831_RS49355	COG4948	Mandelate Racemase Muconate Lactonizing
MRAD2831_RS49360	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MRAD2831_RS49370	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MRAD2831_RS49375	COG0706	membrane insertase activity
MRAD2831_RS49380	COG0594	ribonuclease P activity
MRAD2831_RS49385	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MRAD2831_RS49390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MRAD2831_RS49395	COG0483	inositol monophosphate 1-phosphatase activity
MRAD2831_RS49400	COG0156	8-amino-7-oxononanoate synthase activity
MRAD2831_RS49405	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MRAD2831_RS49420	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MRAD2831_RS49425	COG5328	Belongs to the UPF0262 family
MRAD2831_RS49460	COG2814	Major facilitator Superfamily
MRAD2831_RS49465	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS49500	COG1132	(ABC) transporter
MRAD2831_RS49505	COG2066	Belongs to the glutaminase family
MRAD2831_RS49510	COG2271	Major facilitator Superfamily
MRAD2831_RS49520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MRAD2831_RS49530	COG0604	alcohol dehydrogenase
MRAD2831_RS49530	COG3321	synthase
MRAD2831_RS49530	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS49535	COG0784	Response regulator, receiver
MRAD2831_RS49535	COG4191	Histidine kinase
MRAD2831_RS49540	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MRAD2831_RS49540	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MRAD2831_RS49555	COG1573	uracil-dna glycosylase
MRAD2831_RS49565	COG2137	regulation of response to DNA damage stimulus
MRAD2831_RS49575	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MRAD2831_RS49580	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MRAD2831_RS49590	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MRAD2831_RS49610	COG2169	Transcriptional regulator
MRAD2831_RS49610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MRAD2831_RS49620	COG0217	transcriptional regulatory protein
MRAD2831_RS49625	COG0300	oxidoreductase activity
MRAD2831_RS49630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MRAD2831_RS49645	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
MRAD2831_RS49650	COG0583	DNA-binding transcription factor activity
MRAD2831_RS49680	COG0628	permease
MRAD2831_RS49685	COG4191	Histidine kinase
MRAD2831_RS49685	COG0784	Response regulator, receiver
MRAD2831_RS49695	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MRAD2831_RS49700	COG0277	FAD linked oxidase domain protein
MRAD2831_RS49700	COG0247	lactate metabolic process
MRAD2831_RS49710	COG0557	exoribonuclease II activity
MRAD2831_RS49730	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MRAD2831_RS49735	COG0583	DNA-binding transcription factor activity
MRAD2831_RS49740	COG2223	nitrite transmembrane transporter activity
MRAD2831_RS49750	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MRAD2831_RS49760	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MRAD2831_RS49765	COG2059	Chromate
MRAD2831_RS49770	COG1473	amidohydrolase
MRAD2831_RS49775	COG0789	Transcriptional regulator
MRAD2831_RS49785	COG0625	glutathione transferase activity
MRAD2831_RS49790	COG5002	protein histidine kinase activity
MRAD2831_RS49810	COG0438	transferase activity, transferring glycosyl groups
MRAD2831_RS49825	COG0673	inositol 2-dehydrogenase activity
MRAD2831_RS49860	COG0747	negative chemotaxis
MRAD2831_RS49880	COG0596	Alpha beta hydrolase
MRAD2831_RS49905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MRAD2831_RS49920	COG2814	Major facilitator Superfamily
MRAD2831_RS49925	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MRAD2831_RS49930	COG0228	four-way junction DNA binding
MRAD2831_RS49940	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MRAD2831_RS49960	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MRAD2831_RS49960	COG0596	Alpha beta hydrolase
MRAD2831_RS49960	COG2226	methyltransferase
MRAD2831_RS49965	COG0336	Belongs to the RNA methyltransferase TrmD family
MRAD2831_RS49975	COG0004	ammonium transporteR
MRAD2831_RS49980	COG0347	Belongs to the P(II) protein family
MRAD2831_RS49985	COG1946	Acyl-CoA thioesterase
MRAD2831_RS49990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MRAD2831_RS50000	COG3594	Acyltransferase
MRAD2831_RS50010	COG1216	Glycosyl transferase, family 2
MRAD2831_RS50010	COG0438	transferase activity, transferring glycosyl groups
MRAD2831_RS50020	COG0714	Associated with various cellular activities
MRAD2831_RS50040	COG4166	transmembrane transport
MRAD2831_RS50045	COG4166	transmembrane transport
MRAD2831_RS50050	COG4174	ABC transporter (Permease)
MRAD2831_RS50055	COG1959	2 iron, 2 sulfur cluster binding
MRAD2831_RS50060	COG1017	nitric oxide dioxygenase activity
MRAD2831_RS50060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MRAD2831_RS50080	COG2814	Major facilitator Superfamily
MRAD2831_RS50085	COG3474	cytochrome
MRAD2831_RS50090	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MRAD2831_RS50105	COG1247	-acetyltransferase
MRAD2831_RS50110	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MRAD2831_RS50140	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MRAD2831_RS50160	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MRAD2831_RS50165	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MRAD2831_RS50170	COG0045	succinate-CoA ligase (ADP-forming) activity
MRAD2831_RS50175	COG3404	Formiminotransferase-cyclodeaminase
MRAD2831_RS50180	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MRAD2831_RS50185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MRAD2831_RS50190	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MRAD2831_RS50200	COG0438	transferase activity, transferring glycosyl groups
MRAD2831_RS50205	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MRAD2831_RS50210	COG0840	transmembrane signaling receptor activity
MRAD2831_RS50225	COG0531	amino acid
MRAD2831_RS50230	COG0521	Mo-molybdopterin cofactor biosynthetic process
MRAD2831_RS50235	COG0625	glutathione transferase activity
MRAD2831_RS50240	COG1252	NADH dehydrogenase
MRAD2831_RS50290	COG0432	Pfam Uncharacterised protein family UPF0047
MRAD2831_RS50295	COG1793	dna ligase
MRAD2831_RS50305	COG2226	methyltransferase
MRAD2831_RS50345	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MRAD2831_RS50365	COG4581	dead DEAH box helicase
MRAD2831_RS50375	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MRAD2831_RS50395	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
MRAD2831_RS50415	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MRAD2831_RS50420	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MRAD2831_RS50430	COG1561	YicC-like family, N-terminal region
MRAD2831_RS50435	COG0194	GDP metabolic process
MRAD2831_RS50450	COG4251	negative regulation of phosphorylation
MRAD2831_RS50460	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MRAD2831_RS50465	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MRAD2831_RS50470	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MRAD2831_RS50485	COG0779	Required for maturation of 30S ribosomal subunits
MRAD2831_RS50490	COG0667	Aldo Keto reductase
MRAD2831_RS50495	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
MRAD2831_RS50510	COG2130	NADP-dependent
MRAD2831_RS50515	COG0629	single-stranded DNA binding
MRAD2831_RS50550	COG0243	molybdopterin cofactor binding
MRAD2831_RS50555	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS50560	COG0708	Exodeoxyribonuclease III
MRAD2831_RS50575	COG1674	ftsk spoiiie
MRAD2831_RS50595	COG0537	adenosine 5'-monophosphoramidase activity
MRAD2831_RS50610	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS50625	COG5487	UPF0391 membrane protein
MRAD2831_RS50635	COG0415	Belongs to the DNA photolyase family
MRAD2831_RS50645	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MRAD2831_RS50655	COG0683	leucine binding
MRAD2831_RS50675	COG3265	gluconokinase activity
MRAD2831_RS50690	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MRAD2831_RS50725	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MRAD2831_RS50740	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MRAD2831_RS50745	COG1960	acyl-CoA dehydrogenase activity
MRAD2831_RS50760	COG1454	alcohol dehydrogenase
MRAD2831_RS50775	COG4964	Belongs to the GSP D family
MRAD2831_RS50810	COG2897	thiosulfate sulfurtransferase activity
MRAD2831_RS50845	COG0321	lipoyl(octanoyl) transferase activity
MRAD2831_RS50865	COG1297	OPT oligopeptide transporter protein
MRAD2831_RS50870	COG0513	Belongs to the DEAD box helicase family
MRAD2831_RS50885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MRAD2831_RS50890	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MRAD2831_RS50895	COG0243	molybdopterin cofactor binding
MRAD2831_RS50915	COG2032	superoxide dismutase activity
MRAD2831_RS50925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MRAD2831_RS50935	COG0598	Magnesium transport protein CorA
MRAD2831_RS50950	COG1032	radical SAM domain protein
MRAD2831_RS50955	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS50960	COG1024	Enoyl-CoA hydratase
MRAD2831_RS50965	COG1960	acyl-CoA dehydrogenase activity
MRAD2831_RS50970	COG0009	L-threonylcarbamoyladenylate synthase
MRAD2831_RS50975	COG0655	NAD(P)H dehydrogenase (quinone) activity
MRAD2831_RS50980	COG0583	DNA-binding transcription factor activity
MRAD2831_RS50985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MRAD2831_RS50995	COG0604	alcohol dehydrogenase
MRAD2831_RS51010	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MRAD2831_RS51015	COG0085	RNA polymerase activity
MRAD2831_RS51020	COG0222	ribosome binding
MRAD2831_RS51025	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MRAD2831_RS51035	COG0081	regulation of translation
MRAD2831_RS51040	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MRAD2831_RS51045	COG0250	Participates in transcription elongation, termination and antitermination
MRAD2831_RS51050	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MRAD2831_RS51060	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MRAD2831_RS51070	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
MRAD2831_RS51075	COG3454	Phosphonate metabolism
MRAD2831_RS51080	COG4778	phosphonate C-P lyase system protein PhnL
MRAD2831_RS51085	COG4107	phosphonate C-P lyase system protein PhnK
MRAD2831_RS51095	COG3627	carbon phosphorus lyase activity
MRAD2831_RS51100	COG3626	phosphonate metabolism
MRAD2831_RS51105	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
MRAD2831_RS51110	COG3624	Phosphonate C-P lyase system protein PhnG
MRAD2831_RS51115	COG2188	Transcriptional regulator
MRAD2831_RS51125	COG3639	organic phosphonate transmembrane transporter activity
MRAD2831_RS51130	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
MRAD2831_RS51135	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MRAD2831_RS51145	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
MRAD2831_RS51155	COG0306	phosphate transporter
MRAD2831_RS51165	COG4957	zinc ion binding
MRAD2831_RS51175	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MRAD2831_RS51180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MRAD2831_RS51195	COG1704	LemA family
MRAD2831_RS51200	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MRAD2831_RS51220	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MRAD2831_RS51275	COG1160	GTP binding
MRAD2831_RS51280	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MRAD2831_RS51285	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MRAD2831_RS51290	COG4221	oxidoreductase activity
MRAD2831_RS51295	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MRAD2831_RS51305	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MRAD2831_RS51315	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MRAD2831_RS51330	COG1388	LysM domain
MRAD2831_RS51330	COG1376	ErfK ybiS ycfS ynhG family protein
MRAD2831_RS51335	COG3416	Protein conserved in bacteria
MRAD2831_RS51335	COG2943	transferase activity, transferring hexosyl groups
MRAD2831_RS51340	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
MRAD2831_RS51350	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MRAD2831_RS51365	COG2755	lipolytic protein G-D-S-L family
MRAD2831_RS51365	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MRAD2831_RS51375	COG0783	Belongs to the Dps family
MRAD2831_RS51385	COG4957	zinc ion binding
MRAD2831_RS51395	COG0586	Pfam SNARE associated Golgi protein
MRAD2831_RS51400	COG0678	peroxiredoxin activity
MRAD2831_RS51410	COG1678	Uncharacterized ACR, COG1678
MRAD2831_RS51420	COG0443	Heat shock 70 kDa protein
MRAD2831_RS51425	COG0484	heat shock protein binding
MRAD2831_RS51430	COG3963	phosphatidate phosphatase activity
MRAD2831_RS51450	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MRAD2831_RS51480	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MRAD2831_RS51485	COG3158	transport of potassium into the cell
MRAD2831_RS51515	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MRAD2831_RS51535	COG3842	ATPase activity
MRAD2831_RS51550	COG1178	ABC-type Fe3 transport system permease component
MRAD2831_RS51555	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MRAD2831_RS51560	COG0259	pyridoxamine-phosphate oxidase activity
MRAD2831_RS51580	COG0475	glutathione-regulated potassium exporter activity
MRAD2831_RS51580	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MRAD2831_RS51605	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MRAD2831_RS51610	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MRAD2831_RS51615	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MRAD2831_RS51615	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MRAD2831_RS51630	COG2719	SpoVR family
MRAD2831_RS51635	COG2718	Belongs to the UPF0229 family
MRAD2831_RS51640	COG2766	serine protein kinase
MRAD2831_RS51660	COG0776	regulation of translation
MRAD2831_RS51665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MRAD2831_RS51670	COG0416	fatty acid biosynthetic process
MRAD2831_RS51690	COG0546	phosphoglycolate phosphatase activity
MRAD2831_RS51700	COG1902	pentaerythritol trinitrate reductase activity
MRAD2831_RS51705	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
MRAD2831_RS51715	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MRAD2831_RS51720	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MRAD2831_RS51725	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MRAD2831_RS51735	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS51745	COG1051	belongs to the nudix hydrolase family
MRAD2831_RS51765	COG2818	Glycosylase
MRAD2831_RS51770	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
MRAD2831_RS51780	COG1722	exodeoxyribonuclease VII activity
MRAD2831_RS51785	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MRAD2831_RS51790	COG0473	3-isopropylmalate dehydrogenase activity
MRAD2831_RS51810	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MRAD2831_RS51810	COG0037	tRNA processing
MRAD2831_RS51875	COG2207	Transcriptional regulator
MRAD2831_RS51885	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
MRAD2831_RS51895	COG1595	DNA-templated transcription, initiation
MRAD2831_RS51900	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MRAD2831_RS51925	COG3916	Acyl-homoserine-lactone synthase
MRAD2831_RS51945	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS51975	COG0252	asparaginase activity
MRAD2831_RS51990	COG2201	protein-glutamate methylesterase activity
MRAD2831_RS51995	COG0745	RESPONSE REGULATOR receiver
MRAD2831_RS52000	COG0835	chemotaxis
MRAD2831_RS52005	COG2198	Histidine kinase
MRAD2831_RS52005	COG0643	Histidine kinase
MRAD2831_RS52005	COG0784	Response regulator, receiver
MRAD2831_RS52015	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MRAD2831_RS52050	COG0019	diaminopimelate decarboxylase activity
MRAD2831_RS52055	COG0463	Glycosyl transferase, family 2
MRAD2831_RS52080	COG2851	Citrate transporter
MRAD2831_RS52085	COG0583	DNA-binding transcription factor activity
MRAD2831_RS52100	COG5265	(ABC) transporter
MRAD2831_RS52140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MRAD2831_RS52165	COG4774	siderophore transport
MRAD2831_RS52170	COG3971	2-oxopent-4-enoate hydratase activity
MRAD2831_RS52180	COG0745	RESPONSE REGULATOR receiver
MRAD2831_RS52185	COG1846	Transcriptional regulator
MRAD2831_RS52195	COG2759	Belongs to the formate--tetrahydrofolate ligase family
MRAD2831_RS52200	COG2885	chlorophyll binding
MRAD2831_RS52215	COG1573	uracil-dna glycosylase
MRAD2831_RS52220	COG2321	neutral zinc metallopeptidase
MRAD2831_RS52230	COG0488	(ABC) transporter
MRAD2831_RS52240	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MRAD2831_RS52250	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MRAD2831_RS52260	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MRAD2831_RS52285	COG0445	tRNA wobble uridine modification
MRAD2831_RS52290	COG0357	Ribosomal RNA small subunit methyltransferase G
MRAD2831_RS52325	COG4774	siderophore transport
MRAD2831_RS52345	COG2171	N-acyltransferase activity
MRAD2831_RS52355	COG0745	RESPONSE REGULATOR receiver
MRAD2831_RS52370	COG0495	leucyl-tRNA aminoacylation
MRAD2831_RS52380	COG1253	flavin adenine dinucleotide binding
MRAD2831_RS52420	COG0071	Belongs to the small heat shock protein (HSP20) family
MRAD2831_RS52425	COG0071	Belongs to the small heat shock protein (HSP20) family
MRAD2831_RS52430	COG1674	ftsk spoiiie
MRAD2831_RS52435	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MRAD2831_RS52440	COG2264	protein methyltransferase activity
MRAD2831_RS52450	COG0012	GTP binding
MRAD2831_RS52455	COG0193	aminoacyl-tRNA hydrolase activity
MRAD2831_RS52470	COG0583	DNA-binding transcription factor activity
MRAD2831_RS52475	COG3493	citrate carrier protein
MRAD2831_RS52485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MRAD2831_RS52495	COG2079	MmgE PrpD family protein
MRAD2831_RS52505	COG3618	amidohydrolase
MRAD2831_RS52520	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MRAD2831_RS52530	COG0247	lactate metabolic process
MRAD2831_RS52530	COG0277	FAD linked oxidase domain protein
MRAD2831_RS52620	COG3293	Transposase
MRAD2831_RS52630	COG0582	viral genome integration into host DNA
MRAD2831_RS52735	COG0625	glutathione transferase activity
MRAD2831_RS52750	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MRAD2831_RS52755	COG3300	MHYT domain
MRAD2831_RS52755	COG5001	Diguanylate cyclase
MRAD2831_RS52775	COG2197	response regulator
MRAD2831_RS52820	COG0714	Associated with various cellular activities
MRAD2831_RS52830	COG2010	Cytochrome c
MRAD2831_RS52835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MRAD2831_RS52840	COG4993	Dehydrogenase
MRAD2831_RS52850	COG2124	cytochrome p450
MRAD2831_RS52855	COG5001	Diguanylate cyclase
MRAD2831_RS52860	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MRAD2831_RS52900	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MRAD2831_RS52910	COG1464	Belongs to the NlpA lipoprotein family
MRAD2831_RS52915	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MRAD2831_RS52920	COG2011	ABC-type metal ion transport system permease component
MRAD2831_RS52940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MRAD2831_RS52995	COG4957	zinc ion binding
MRAD2831_RS53010	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MRAD2831_RS53015	COG0346	lactoylglutathione lyase activity
MRAD2831_RS53030	COG0747	negative chemotaxis
MRAD2831_RS53070	COG5001	Diguanylate cyclase
MRAD2831_RS53070	COG3300	MHYT domain
MRAD2831_RS53080	COG2080	2 iron, 2 sulfur cluster binding
MRAD2831_RS53085	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MRAD2831_RS53090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MRAD2831_RS53100	COG4773	Receptor
MRAD2831_RS53110	COG0784	Response regulator, receiver
MRAD2831_RS53110	COG4191	Histidine kinase
MRAD2831_RS53120	COG0784	Response regulator, receiver
MRAD2831_RS53125	COG4251	negative regulation of phosphorylation
MRAD2831_RS53160	COG0754	glutathionylspermidine amidase activity
MRAD2831_RS53170	COG3766	membrane
MRAD2831_RS53185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MRAD2831_RS53195	COG0237	dephospho-CoA kinase activity
MRAD2831_RS53200	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MRAD2831_RS53210	COG0424	maF-like protein
MRAD2831_RS53215	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MRAD2831_RS53225	COG0124	histidyl-tRNA synthetase
MRAD2831_RS53235	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MRAD2831_RS53240	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MRAD2831_RS53245	COG0583	DNA-binding transcription factor activity
MRAD2831_RS53260	COG1981	membrane
MRAD2831_RS53265	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MRAD2831_RS53270	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MRAD2831_RS53300	COG2304	oxidoreductase activity
MRAD2831_RS53315	COG0714	Associated with various cellular activities
MRAD2831_RS53320	COG1285	pathogenesis
MRAD2831_RS53335	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MRAD2831_RS53340	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MRAD2831_RS53345	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MRAD2831_RS53360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MRAD2831_RS53365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MRAD2831_RS53390	COG4239	(ABC) transporter, permease
MRAD2831_RS53395	COG4957	zinc ion binding
MRAD2831_RS53400	COG0277	FAD linked oxidase domain protein
MRAD2831_RS53430	COG0784	Response regulator, receiver
MRAD2831_RS53430	COG4191	Histidine kinase
MRAD2831_RS53435	COG2885	chlorophyll binding
MRAD2831_RS53445	COG0037	tRNA processing
MRAD2831_RS53450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MRAD2831_RS53460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MRAD2831_RS53490	COG3264	Mechanosensitive ion channel
MRAD2831_RS53490	COG1196	nuclear chromosome segregation
MRAD2831_RS53495	COG5002	protein histidine kinase activity
MRAD2831_RS53495	COG3447	MASE1 domain protein
MRAD2831_RS53495	COG5001	Diguanylate cyclase
MRAD2831_RS53505	COG1132	(ABC) transporter
MRAD2831_RS53535	COG5001	Diguanylate cyclase
MRAD2831_RS53545	COG0438	transferase activity, transferring glycosyl groups
MRAD2831_RS53570	COG0047	phosphoribosylformylglycinamidine synthase activity
MRAD2831_RS53575	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MRAD2831_RS53585	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
MRAD2831_RS53605	COG0601	transmembrane transport
MRAD2831_RS53610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MRAD2831_RS53615	COG0444	Belongs to the ABC transporter superfamily
MRAD2831_RS53620	COG4608	Belongs to the ABC transporter superfamily
MRAD2831_RS53625	COG3964	amidohydrolase
MRAD2831_RS53635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MRAD2831_RS53640	COG2855	membrane
MRAD2831_RS53645	COG4957	zinc ion binding
MRAD2831_RS53655	COG4172	Belongs to the ABC transporter superfamily
MRAD2831_RS53675	COG0747	negative chemotaxis
MRAD2831_RS53690	COG2134	cdp-diacylglycerol pyrophosphatase
MRAD2831_RS53705	COG4191	Histidine kinase
MRAD2831_RS53705	COG0784	Response regulator, receiver
MRAD2831_RS53710	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MRAD2831_RS53770	COG2353	YceI-like domain
MRAD2831_RS53790	COG1982	Orn Lys Arg decarboxylase major
MRAD2831_RS53795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MRAD2831_RS53810	COG0626	cystathionine gamma-synthase activity
MRAD2831_RS53820	COG0753	catalase activity
MRAD2831_RS53830	COG3300	MHYT domain
MRAD2831_RS53830	COG5001	Diguanylate cyclase
MRAD2831_RS53875	COG0583	DNA-binding transcription factor activity
MRAD2831_RS53890	COG2094	Belongs to the DNA glycosylase MPG family
MRAD2831_RS53910	COG0683	leucine binding
MRAD2831_RS53935	COG0154	amidase activity
MRAD2831_RS53960	COG0784	Response regulator, receiver
MRAD2831_RS53960	COG4191	Histidine kinase
MRAD2831_RS53980	COG2255	four-way junction helicase activity
MRAD2831_RS53985	COG0625	glutathione transferase activity
MRAD2831_RS53990	COG0747	negative chemotaxis
MRAD2831_RS53995	COG3300	MHYT domain
MRAD2831_RS53995	COG5001	Diguanylate cyclase
MRAD2831_RS54025	COG0546	phosphoglycolate phosphatase activity
MRAD2831_RS54030	COG3059	membrane
MRAD2831_RS54050	COG1960	acyl-CoA dehydrogenase activity
MRAD2831_RS54055	COG0183	Belongs to the thiolase family
MRAD2831_RS54070	COG3237	CsbD-like
MRAD2831_RS54075	COG3237	CsbD-like
MRAD2831_RS54090	COG3237	CsbD-like
MRAD2831_RS54125	COG2030	dehydratase
MRAD2831_RS54145	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MRAD2831_RS54150	COG1376	ErfK ybiS ycfS ynhG family protein
MRAD2831_RS54160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MRAD2831_RS54170	COG0747	negative chemotaxis
MRAD2831_RS54175	COG0601	transmembrane transport
MRAD2831_RS54180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MRAD2831_RS54185	COG0444	Belongs to the ABC transporter superfamily
MRAD2831_RS54195	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MRAD2831_RS54220	COG2080	2 iron, 2 sulfur cluster binding
MRAD2831_RS54225	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MRAD2831_RS54230	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MRAD2831_RS54240	COG0625	glutathione transferase activity
MRAD2831_RS54245	COG4783	chaperone-mediated protein folding
MRAD2831_RS54255	COG1396	sequence-specific DNA binding
MRAD2831_RS54260	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MRAD2831_RS54265	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MRAD2831_RS54270	COG3920	Histidine kinase
MRAD2831_RS54280	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MRAD2831_RS54305	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MRAD2831_RS54310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MRAD2831_RS54315	COG0165	Argininosuccinate lyase
MRAD2831_RS54340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MRAD2831_RS54350	COG0784	Response regulator, receiver
MRAD2831_RS54350	COG4191	Histidine kinase
MRAD2831_RS54355	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MRAD2831_RS54395	COG0114	fumarate hydratase activity
MRAD2831_RS54400	COG2124	cytochrome p450
MRAD2831_RS54400	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MRAD2831_RS54425	COG0330	HflC and HflK could
MRAD2831_RS54430	COG0330	HflC and HflK could
MRAD2831_RS54445	COG3830	Belongs to the UPF0237 family
MRAD2831_RS54445	COG0560	Phosphoserine phosphatase
MRAD2831_RS54450	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MRAD2831_RS54455	COG2084	Dehydrogenase
MRAD2831_RS54460	COG1966	Carbon starvation protein
MRAD2831_RS54465	COG2879	small protein
MRAD2831_RS54485	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
MRAD2831_RS54495	COG5001	Diguanylate cyclase
MRAD2831_RS54495	COG3706	GGDEF domain
MRAD2831_RS54495	COG2203	Gaf domain
MRAD2831_RS54495	COG4251	negative regulation of phosphorylation
MRAD2831_RS54500	COG3178	'Phosphotransferase
MRAD2831_RS54505	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MRAD2831_RS54550	COG1215	transferase activity, transferring glycosyl groups
MRAD2831_RS54560	COG2244	polysaccharide biosynthetic process
MRAD2831_RS54580	COG0438	transferase activity, transferring glycosyl groups
MRAD2831_RS54585	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MRAD2831_RS54630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MRAD2831_RS54640	COG0583	DNA-binding transcription factor activity
MRAD2831_RS54650	COG0596	Alpha beta hydrolase
MRAD2831_RS54665	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MRAD2831_RS54670	COG3639	organic phosphonate transmembrane transporter activity
MRAD2831_RS54675	COG3639	organic phosphonate transmembrane transporter activity
MRAD2831_RS54680	COG1473	amidohydrolase
MRAD2831_RS54690	COG0601	transmembrane transport
MRAD2831_RS54695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MRAD2831_RS54715	COG3706	GGDEF domain
MRAD2831_RS54730	COG4558	Periplasmic binding protein
MRAD2831_RS54735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MRAD2831_RS54740	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
MRAD2831_RS54755	COG1215	transferase activity, transferring glycosyl groups
MRAD2831_RS54765	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MRAD2831_RS54765	COG2755	lipolytic protein G-D-S-L family
MRAD2831_RS54780	COG2273	Hydrolase Family 16
MRAD2831_RS54785	COG1215	transferase activity, transferring glycosyl groups
MRAD2831_RS54810	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MRAD2831_RS54815	COG2197	response regulator
MRAD2831_RS54820	COG0438	transferase activity, transferring glycosyl groups
MRAD2831_RS54840	COG0673	inositol 2-dehydrogenase activity
MRAD2831_RS54855	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MRAD2831_RS54885	COG1215	transferase activity, transferring glycosyl groups
MRAD2831_RS54890	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MRAD2831_RS54915	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MRAD2831_RS54920	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MRAD2831_RS54930	COG1999	signal sequence binding
MRAD2831_RS54950	COG0517	IMP dehydrogenase activity
MRAD2831_RS54950	COG0516	GMP reductase activity
MRAD2831_RS54960	COG1752	Esterase of the alpha-beta hydrolase superfamily
MRAD2831_RS54965	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MRAD2831_RS54970	COG0302	gtp cyclohydrolase
MRAD2831_RS54980	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MRAD2831_RS54985	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MRAD2831_RS54990	COG3395	kinase activity
MRAD2831_RS55010	COG0840	transmembrane signaling receptor activity
MRAD2831_RS55015	COG1530	ribonuclease E activity
MRAD2831_RS55015	COG1530	ribonuclease E activity
MRAD2831_RS55020	COG0247	lactate metabolic process
MRAD2831_RS55025	COG0277	FAD linked oxidase domain protein
MRAD2831_RS55060	COG4948	Mandelate Racemase Muconate Lactonizing
MRAD2831_RS55085	COG2205	protein histidine kinase activity
MRAD2831_RS55115	COG4957	zinc ion binding
MRAD2831_RS55125	COG0408	coproporphyrinogen oxidase activity
MRAD2831_RS55130	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MRAD2831_RS55150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MRAD2831_RS55165	COG3214	Protein conserved in bacteria
MRAD2831_RS55170	COG1275	C4-dicarboxylate transporter malic acid transport protein
MRAD2831_RS55175	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS55180	COG0596	Alpha beta hydrolase
MRAD2831_RS55200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MRAD2831_RS55200	COG1017	nitric oxide dioxygenase activity
MRAD2831_RS55205	COG0625	glutathione transferase activity
MRAD2831_RS55210	COG1335	isochorismatase
MRAD2831_RS55215	COG0583	DNA-binding transcription factor activity
MRAD2831_RS55220	COG1741	Belongs to the pirin family
MRAD2831_RS55235	COG3038	cytochrome b561
MRAD2831_RS55320	COG2205	protein histidine kinase activity
MRAD2831_RS55350	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MRAD2831_RS55385	COG0477	Major facilitator Superfamily
MRAD2831_RS55395	COG0163	prenyltransferase activity
MRAD2831_RS55420	COG3246	L-lysine catabolic process to acetate
MRAD2831_RS55430	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MRAD2831_RS55435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MRAD2831_RS55440	COG2801	Transposase and inactivated derivatives
MRAD2831_RS55465	COG0583	DNA-binding transcription factor activity
MRAD2831_RS55470	COG0747	negative chemotaxis
MRAD2831_RS55485	COG0583	DNA-binding transcription factor activity
MRAD2831_RS55510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MRAD2831_RS55520	COG1012	belongs to the aldehyde dehydrogenase family
MRAD2831_RS55530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MRAD2831_RS55535	COG4608	Belongs to the ABC transporter superfamily
MRAD2831_RS55540	COG0444	Belongs to the ABC transporter superfamily
MRAD2831_RS55545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MRAD2831_RS55555	COG0747	negative chemotaxis
MRAD2831_RS55565	COG1228	amidohydrolase
MRAD2831_RS55575	COG2084	Dehydrogenase
MRAD2831_RS55590	COG1376	ErfK ybiS ycfS ynhG family protein
MRAD2831_RS55610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MRAD2831_RS55635	COG1960	acyl-CoA dehydrogenase activity
MRAD2831_RS55650	COG3300	MHYT domain
MRAD2831_RS55650	COG5001	Diguanylate cyclase
MRAD2831_RS55695	COG0590	tRNA wobble adenosine to inosine editing
MRAD2831_RS55725	COG1215	transferase activity, transferring glycosyl groups
MRAD2831_RS55755	COG3224	Antibiotic biosynthesis monooxygenase
MRAD2831_RS55770	COG0069	glutamate synthase activity
MRAD2831_RS55775	COG2218	PFAM glutamate synthase alpha subunit domain protein
MRAD2831_RS55780	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MRAD2831_RS55790	COG0745	RESPONSE REGULATOR receiver
MRAD2831_RS55800	COG0840	transmembrane signaling receptor activity
MRAD2831_RS55805	COG0643	Histidine kinase
MRAD2831_RS55805	COG2198	Histidine kinase
MRAD2831_RS55810	COG0835	chemotaxis
MRAD2831_RS55810	COG0784	Response regulator, receiver
MRAD2831_RS55815	COG0840	transmembrane signaling receptor activity
MRAD2831_RS55820	COG0835	chemotaxis
MRAD2831_RS55830	COG2201	protein-glutamate methylesterase activity
MRAD2831_RS55840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MRAD2831_RS55845	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MRAD2831_RS55850	COG1522	sequence-specific DNA binding
MRAD2831_RS55860	COG0583	DNA-binding transcription factor activity
MRAD2831_RS55870	COG1012	belongs to the aldehyde dehydrogenase family
MRAD2831_RS55880	COG1473	amidohydrolase
MRAD2831_RS55885	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
MRAD2831_RS55900	COG2188	Transcriptional regulator
MRAD2831_RS55905	COG2814	Major facilitator Superfamily
MRAD2831_RS55920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MRAD2831_RS55920	COG1116	anion transmembrane transporter activity
MRAD2831_RS55925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MRAD2831_RS55945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MRAD2831_RS55995	COG4957	zinc ion binding
MRAD2831_RS56010	COG1741	Belongs to the pirin family
MRAD2831_RS56015	COG0667	Aldo Keto reductase
MRAD2831_RS56020	COG1566	PFAM secretion protein HlyD family protein
MRAD2831_RS56035	COG1294	oxidase, subunit
MRAD2831_RS56040	COG1271	oxidase subunit
MRAD2831_RS56045	COG0579	oxidoreductase
MRAD2831_RS56055	COG0028	Belongs to the TPP enzyme family
MRAD2831_RS56060	COG0114	fumarate hydratase activity
MRAD2831_RS56070	COG0372	Belongs to the citrate synthase family
MRAD2831_RS56080	COG0583	DNA-binding transcription factor activity
MRAD2831_RS56125	COG0596	Alpha beta hydrolase
MRAD2831_RS56135	COG4957	zinc ion binding
MRAD2831_RS56170	COG1174	glycine betaine transport
MRAD2831_RS56175	COG1125	glycine betaine transport
MRAD2831_RS56180	COG1174	glycine betaine transport
MRAD2831_RS56185	COG1732	Glycine betaine
MRAD2831_RS56195	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MRAD2831_RS56215	COG4957	zinc ion binding
MRAD2831_RS56230	COG2134	cdp-diacylglycerol pyrophosphatase
MRAD2831_RS56290	COG2813	Specifically methylates the guanine in position
MRAD2831_RS56295	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
MRAD2831_RS56310	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS56325	COG1297	OPT oligopeptide transporter protein
MRAD2831_RS56335	COG1126	abc transporter atp-binding protein
MRAD2831_RS56340	COG0765	amino acid transport
MRAD2831_RS56345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MRAD2831_RS56360	COG1271	oxidase subunit
MRAD2831_RS56365	COG1294	oxidase, subunit
MRAD2831_RS56380	COG1802	Transcriptional regulator
MRAD2831_RS56385	COG0583	DNA-binding transcription factor activity
MRAD2831_RS56390	COG0346	lactoylglutathione lyase activity
MRAD2831_RS56395	COG0400	carboxylic ester hydrolase activity
MRAD2831_RS56415	COG0494	nUDIX hydrolase
MRAD2831_RS56425	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MRAD2831_RS56435	COG2972	Histidine kinase
MRAD2831_RS56435	COG0840	transmembrane signaling receptor activity
MRAD2831_RS56465	COG1702	phosphate starvation-inducible protein PhoH
MRAD2831_RS56470	COG0210	DNA helicase
MRAD2831_RS56500	COG2166	iron-sulfur cluster assembly
MRAD2831_RS56505	COG3920	Histidine kinase
MRAD2831_RS56530	COG4695	Portal protein
MRAD2831_RS56545	COG0783	Belongs to the Dps family
MRAD2831_RS56550	COG3591	Belongs to the peptidase S1B family
MRAD2831_RS56665	COG4235	cytochrome complex assembly
MRAD2831_RS56670	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
MRAD2831_RS56675	COG1138	Cytochrome C-type biogenesis protein
MRAD2831_RS56680	COG3088	subunit of a heme lyase
MRAD2831_RS56685	COG0625	glutathione transferase activity
MRAD2831_RS56700	COG3383	formate dehydrogenase (NAD+) activity
MRAD2831_RS56730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MRAD2831_RS56745	COG0784	Response regulator, receiver
MRAD2831_RS56780	COG1376	ErfK ybiS ycfS ynhG family protein
MRAD2831_RS56795	COG0628	permease
MRAD2831_RS56800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MRAD2831_RS56805	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MRAD2831_RS56815	COG1278	Cold shock
MRAD2831_RS56835	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MRAD2831_RS56840	COG1324	tolerance protein
MRAD2831_RS56910	COG2030	dehydratase
MRAD2831_RS56950	COG1338	Plays a role in the flagellum-specific transport system
MRAD2831_RS56975	COG2204	response regulator
MRAD2831_RS56980	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MRAD2831_RS56990	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MRAD2831_RS56995	COG1766	The M ring may be actively involved in energy transduction
MRAD2831_RS57015	COG0482	sulfurtransferase activity
MRAD2831_RS57020	COG2226	methyltransferase
MRAD2831_RS57030	COG4191	Histidine kinase
MRAD2831_RS57035	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MRAD2831_RS57065	COG0436	Aminotransferase
MRAD2831_RS57090	COG0405	Gamma-glutamyltransferase
MRAD2831_RS57100	COG0444	Belongs to the ABC transporter superfamily
MRAD2831_RS57110	COG0601	transmembrane transport
MRAD2831_RS57150	COG3493	citrate carrier protein
MRAD2831_RS57165	COG0431	NADPH-dependent FMN reductase
MRAD2831_RS57165	COG1053	succinate dehydrogenase
MRAD2831_RS57165	COG3976	FMN-binding domain protein
MRAD2831_RS57170	COG2887	Belongs to the helicase family. UvrD subfamily
MRAD2831_RS57175	COG1960	acyl-CoA dehydrogenase activity
MRAD2831_RS57200	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
MRAD2831_RS57240	COG0297	glycogen (starch) synthase activity
MRAD2831_RS57245	COG0330	HflC and HflK could
MRAD2831_RS57270	COG1555	photosystem II stabilization
MRAD2831_RS57270	COG1596	polysaccharide export
MRAD2831_RS57275	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MRAD2831_RS57325	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MRAD2831_RS57340	COG0174	glutamine synthetase
MRAD2831_RS57345	COG0174	glutamine synthetase
MRAD2831_RS57355	COG0347	Belongs to the P(II) protein family
MRAD2831_RS57360	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MRAD2831_RS57360	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MRAD2831_RS57375	COG0544	peptidyl-prolyl cis-trans isomerase activity
MRAD2831_RS57380	COG0740	serine-type endopeptidase activity
MRAD2831_RS57385	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MRAD2831_RS57390	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MRAD2831_RS57410	COG0596	Alpha beta hydrolase
MRAD2831_RS57415	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS57420	COG0662	Cupin 2, conserved barrel domain protein
MRAD2831_RS57420	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
MRAD2831_RS57425	COG1921	L-seryl-tRNASec selenium transferase activity
MRAD2831_RS57430	COG1846	Transcriptional regulator
MRAD2831_RS57440	COG0243	molybdopterin cofactor binding
MRAD2831_RS57455	COG0583	DNA-binding transcription factor activity
MRAD2831_RS57460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MRAD2831_RS57465	COG2271	Major facilitator Superfamily
MRAD2831_RS57475	COG0402	S-adenosylhomocysteine deaminase activity
MRAD2831_RS57485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MRAD2831_RS57595	COG4957	zinc ion binding
MRAD2831_RS57765	COG3038	cytochrome b561
MRAD2831_RS57805	COG4251	negative regulation of phosphorylation
MRAD2831_RS57825	COG4191	Histidine kinase
MRAD2831_RS57825	COG0784	Response regulator, receiver
MRAD2831_RS57830	COG1366	Belongs to the anti-sigma-factor antagonist family
MRAD2831_RS57835	COG1366	Belongs to the anti-sigma-factor antagonist family
MRAD2831_RS57840	COG2172	sigma factor antagonist activity
MRAD2831_RS57855	COG0784	Response regulator, receiver
MRAD2831_RS57855	COG4191	Histidine kinase
MRAD2831_RS57860	COG3920	Histidine kinase
MRAD2831_RS57860	COG2202	Pas domain
MRAD2831_RS57895	COG2814	Major facilitator Superfamily
MRAD2831_RS57920	COG2514	catechol 2,3-dioxygenase activity
MRAD2831_RS57925	COG2353	YceI-like domain
MRAD2831_RS57935	COG2353	YceI-like domain
MRAD2831_RS57940	COG0583	DNA-binding transcription factor activity
MRAD2831_RS57945	COG0702	epimerase
MRAD2831_RS57950	COG1733	regulation of RNA biosynthetic process
MRAD2831_RS57980	COG0583	DNA-binding transcription factor activity
MRAD2831_RS58015	COG2855	membrane
MRAD2831_RS58020	COG0588	phosphoglycerate mutase activity
MRAD2831_RS58090	COG1902	pentaerythritol trinitrate reductase activity
MRAD2831_RS58100	COG0693	protein deglycase activity
MRAD2831_RS58105	COG0656	L-ascorbic acid biosynthetic process
MRAD2831_RS58110	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MRAD2831_RS58240	COG3246	L-lysine catabolic process to acetate
MRAD2831_RS58245	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MRAD2831_RS58250	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MRAD2831_RS58255	COG0418	dihydroorotase activity
MRAD2831_RS58260	COG0154	amidase activity
MRAD2831_RS58265	COG0028	Belongs to the TPP enzyme family
MRAD2831_RS58275	COG0625	glutathione transferase activity
MRAD2831_RS58280	COG1309	transcriptional regulator
MRAD2831_RS58285	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MRAD2831_RS58295	COG0840	transmembrane signaling receptor activity
MRAD2831_RS58300	COG4106	trans-aconitate 2-methyltransferase activity
MRAD2831_RS58310	COG0180	Tryptophanyl-tRNA synthetase
MRAD2831_RS58315	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MRAD2831_RS58325	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MRAD2831_RS58330	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MRAD2831_RS58335	COG0564	pseudouridine synthase activity
MRAD2831_RS58340	COG0552	protein localization to endoplasmic reticulum
MRAD2831_RS58345	COG2917	probably involved in intracellular septation
MRAD2831_RS58350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MRAD2831_RS58360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MRAD2831_RS58375	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MRAD2831_RS58385	COG0142	geranyltranstransferase activity
MRAD2831_RS58405	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MRAD2831_RS58410	COG0303	'Molybdopterin
MRAD2831_RS58430	COG0438	transferase activity, transferring glycosyl groups
MRAD2831_RS58460	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MRAD2831_RS58465	COG1692	metallophosphoesterase
MRAD2831_RS58485	COG1132	(ABC) transporter
MRAD2831_RS58525	COG0693	protein deglycase activity
MRAD2831_RS58540	COG1278	Cold shock
MRAD2831_RS58550	COG0483	inositol monophosphate 1-phosphatase activity
MRAD2831_RS58560	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MRAD2831_RS58595	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
MRAD2831_RS58600	COG0489	protein tyrosine kinase activity
MRAD2831_RS58600	COG3206	protein involved in exopolysaccharide biosynthesis
MRAD2831_RS58610	COG0438	transferase activity, transferring glycosyl groups
MRAD2831_RS58665	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MRAD2831_RS58670	COG0322	excinuclease ABC activity
MRAD2831_RS58680	COG1376	ErfK ybiS ycfS ynhG family protein
MRAD2831_RS58690	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MRAD2831_RS58695	COG1496	oxidoreductase activity
MRAD2831_RS58710	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MRAD2831_RS58720	COG3386	PFAM SMP-30 Gluconolaconase
MRAD2831_RS58730	COG0305	Participates in initiation and elongation during chromosome replication
MRAD2831_RS58735	COG0359	binds to the 23S rRNA
MRAD2831_RS58745	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MRAD2831_RS58750	COG0360	Binds together with S18 to 16S ribosomal RNA
MRAD2831_RS58760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MRAD2831_RS58765	COG1562	ergosterol biosynthetic process
MRAD2831_RS58770	COG1562	ergosterol biosynthetic process
MRAD2831_RS58775	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MRAD2831_RS58780	COG1657	PFAM Prenyltransferase squalene oxidase
MRAD2831_RS58800	COG0525	valine-tRNA ligase activity
MRAD2831_RS58825	COG3300	MHYT domain
MRAD2831_RS58825	COG5001	Diguanylate cyclase
MRAD2831_RS58835	COG0590	tRNA wobble adenosine to inosine editing
MRAD2831_RS58850	COG3386	PFAM SMP-30 Gluconolaconase
MRAD2831_RS58855	COG0625	glutathione transferase activity
MRAD2831_RS58875	COG0542	response to heat
MRAD2831_RS58895	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MRAD2831_RS58900	COG2072	flavoprotein involved in K transport
MRAD2831_RS58920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MRAD2831_RS58940	COG2239	Acts as a magnesium transporter
MRAD2831_RS58945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MRAD2831_RS58950	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MRAD2831_RS58955	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MRAD2831_RS58960	COG2080	2 iron, 2 sulfur cluster binding
MRAD2831_RS58965	COG0656	L-ascorbic acid biosynthetic process
MRAD2831_RS58975	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MRAD2831_RS58985	COG3158	transport of potassium into the cell
MRAD2831_RS58990	COG0326	Molecular chaperone. Has ATPase activity
MRAD2831_RS59005	COG1137	ATPase activity
MRAD2831_RS59015	COG2271	Major facilitator Superfamily
MRAD2831_RS59030	COG1216	Glycosyl transferase, family 2
MRAD2831_RS59045	COG1045	serine acetyltransferase
MRAD2831_RS59135	COG0477	Major facilitator Superfamily
MRAD2831_RS59155	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS59165	COG1028	Short-chain dehydrogenase reductase Sdr
MRAD2831_RS59175	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MRAD2831_RS59190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MRAD2831_RS59200	COG0411	ABC transporter
MRAD2831_RS59220	COG2198	Histidine kinase
MRAD2831_RS59220	COG0784	Response regulator, receiver
MRAD2831_RS59220	COG5002	protein histidine kinase activity
MRAD2831_RS59255	COG1120	ATPase activity
MRAD2831_RS59260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MRAD2831_RS59265	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MRAD2831_RS59275	COG0484	heat shock protein binding
MRAD2831_RS59280	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MRAD2831_RS59290	COG2326	polyphosphate kinase activity
MRAD2831_RS59305	COG3706	GGDEF domain
MRAD2831_RS59325	COG0121	glutamine amidotransferase
MRAD2831_RS59330	COG0784	Response regulator, receiver
MRAD2831_RS59330	COG4191	Histidine kinase
MRAD2831_RS59335	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MRAD2831_RS59355	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MRAD2831_RS59360	COG0745	RESPONSE REGULATOR receiver
MRAD2831_RS59370	COG1749	Flagellar hook protein flgE
MRAD2831_RS59400	COG3951	Flagellar rod assembly protein muramidase FlgJ
MRAD2831_RS59405	COG1706	bacterial-type flagellum-dependent cell motility
MRAD2831_RS59420	COG0443	Heat shock 70 kDa protein
MRAD2831_RS59425	COG1696	Membrane protein involved in D-alanine export
MRAD2831_RS59465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MRAD2831_RS59470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MRAD2831_RS59475	COG2226	methyltransferase
MRAD2831_RS59480	COG2814	Major facilitator Superfamily
MRAD2831_RS59495	COG3045	CreA protein
MRAD2831_RS59505	COG0215	cysteine-tRNA ligase activity
MRAD2831_RS59530	COG0392	lysyltransferase activity
MRAD2831_RS59535	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MRAD2831_RS59555	COG4191	Histidine kinase
MRAD2831_RS59565	COG2239	Acts as a magnesium transporter
MRAD2831_RS59590	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MRAD2831_RS59595	COG1132	(ABC) transporter
MRAD2831_RS59615	COG0138	bifunctional purine biosynthesis protein purh
MRAD2831_RS59640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MRAD2831_RS59660	COG1376	ErfK ybiS ycfS ynhG family protein
MRAD2831_RS59685	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MRAD2831_RS59700	COG3161	chorismate lyase activity
MRAD2831_RS59705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MRAD2831_RS59710	COG0508	dehydrogenase complex catalyzes the overall conversion of
MRAD2831_RS59720	COG1522	sequence-specific DNA binding
MRAD2831_RS59740	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MRAD2831_RS59745	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MRAD2831_RS59785	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MRAD2831_RS59795	COG3046	protein related to deoxyribodipyrimidine photolyase
MRAD2831_RS59805	COG3932	Exopolysaccharide synthesis, ExoD
MRAD2831_RS59810	COG1846	Transcriptional regulator
MRAD2831_RS59820	COG0113	porphobilinogen synthase activity
MRAD2831_RS59840	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MRAD2831_RS59855	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MRAD2831_RS59865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MRAD2831_RS59870	COG0564	pseudouridine synthase activity
MRAD2831_RS59890	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MRAD2831_RS59910	COG3237	CsbD-like
MRAD2831_RS59925	COG3237	CsbD-like
MRAD2831_RS60035	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MRAD2831_RS60140	COG1783	phage Terminase large subunit
MRAD2831_RS60170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MRAD2831_RS60210	COG1598	PFAM Uncharacterised protein family UPF0150
MRAD2831_RS60295	COG1396	sequence-specific DNA binding
MRAD2831_RS60365	COG0582	viral genome integration into host DNA
MRAD2831_RS60375	COG5001	Diguanylate cyclase
MRAD2831_RS60405	COG1960	acyl-CoA dehydrogenase activity
MRAD2831_RS60425	COG2197	response regulator
MRAD2831_RS60430	COG3916	Acyl-homoserine-lactone synthase
MRAD2831_RS60440	COG0538	isocitrate dehydrogenase activity
MRAD2831_RS60455	COG4133	protoheme IX ABC transporter activity
MRAD2831_RS60460	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MRAD2831_RS60615	COG0070	glutamate synthase
MRAD2831_RS60615	COG0069	glutamate synthase activity
MRAD2831_RS60615	COG0067	glutamate synthase
MRAD2831_RS60955	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MRAD2831_RS61100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MRAD2831_RS61135	COG1012	belongs to the aldehyde dehydrogenase family
MRAD2831_RS61300	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MRAD2831_RS61690	COG0697	spore germination
MRAD2831_RS61705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MRAD2831_RS61930	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MRAD2831_RS61945	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MRAD2831_RS62240	COG2801	Transposase and inactivated derivatives
MRAD2831_RS62450	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
MRAD2831_RS62455	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
MRAD2831_RS62595	COG1132	(ABC) transporter
MRAD2831_RS62670	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MRAD2831_RS63050	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MRAD2831_RS63425	COG1024	Enoyl-CoA hydratase
MRAD2831_RS63425	COG1250	3-hydroxyacyl-CoA dehydrogenase
MRAD2831_RS63450	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MRAD2831_RS63525	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MRAD2831_RS63620	COG0583	DNA-binding transcription factor activity
MRAD2831_RS63785	COG1250	3-hydroxyacyl-CoA dehydrogenase
MRAD2831_RS63870	COG1250	3-hydroxyacyl-CoA dehydrogenase
MRAD2831_RS63870	COG1024	Enoyl-CoA hydratase
MRAD2831_RS64685	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MRAD2831_RS64735	COG4372	Transposase
MRAD2831_RS64770	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner