locus-tag	class	description
JT25_RS00035	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JT25_RS00060	COG2198	Histidine kinase
JT25_RS00060	COG2205	protein histidine kinase activity
JT25_RS00060	COG0784	Response regulator, receiver
JT25_RS00085	COG0442	prolyl-tRNA aminoacylation
JT25_RS00095	COG0653	protein targeting
JT25_RS00140	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JT25_RS00145	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JT25_RS00150	COG0045	succinate-CoA ligase (ADP-forming) activity
JT25_RS00160	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JT25_RS00170	COG0484	heat shock protein binding
JT25_RS00185	COG1858	cytochrome C peroxidase
JT25_RS00195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JT25_RS00240	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JT25_RS00260	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
JT25_RS00270	COG1758	RNA polymerase activity
JT25_RS00275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JT25_RS00285	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JT25_RS00290	COG3161	chorismate lyase activity
JT25_RS00300	COG4260	virion core protein, lumpy skin disease virus
JT25_RS00305	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JT25_RS00325	COG2983	Belongs to the UPF0260 family
JT25_RS00330	COG2177	Part of the ABC transporter FtsEX involved in
JT25_RS00335	COG2884	Cell division ATP-binding protein ftsE
JT25_RS00340	COG0552	protein localization to endoplasmic reticulum
JT25_RS00365	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
JT25_RS00370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JT25_RS00375	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JT25_RS00380	COG2703	oxygen carrier activity
JT25_RS00385	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JT25_RS00390	COG2226	methyltransferase
JT25_RS00395	COG2267	carboxylic ester hydrolase activity
JT25_RS00400	COG0156	8-amino-7-oxononanoate synthase activity
JT25_RS00405	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JT25_RS00445	COG0436	Aminotransferase
JT25_RS00450	COG1131	(ABC) transporter
JT25_RS00460	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JT25_RS00460	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JT25_RS00465	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JT25_RS00465	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JT25_RS00480	COG0438	transferase activity, transferring glycosyl groups
JT25_RS00490	COG3328	transposase activity
JT25_RS00585	COG4232	protein-disulfide reductase activity
JT25_RS00645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JT25_RS00655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JT25_RS00670	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JT25_RS00710	COG3008	intermembrane lipid transfer
JT25_RS00710	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JT25_RS00715	COG1127	ABC transporter
JT25_RS00720	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JT25_RS00730	COG0745	RESPONSE REGULATOR receiver
JT25_RS00735	COG0629	single-stranded DNA binding
JT25_RS00740	COG2814	Major facilitator Superfamily
JT25_RS00745	COG2267	carboxylic ester hydrolase activity
JT25_RS00750	COG0671	phosphoesterase, PA-phosphatase related
JT25_RS00750	COG2453	phosphatase
JT25_RS00755	COG0575	Belongs to the CDS family
JT25_RS00770	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JT25_RS00810	COG3706	GGDEF domain
JT25_RS00815	COG1301	dicarboxylic acid transport
JT25_RS00820	COG3012	SEC-C Motif Domain Protein
JT25_RS00825	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JT25_RS00830	COG0058	SHG alpha-glucan phosphorylase activity
JT25_RS00835	COG0653	protein targeting
JT25_RS00840	COG0569	domain protein
JT25_RS00860	COG3622	Belongs to the hyi family
JT25_RS00885	COG1730	sister chromatid segregation
JT25_RS00890	COG2827	Endonuclease containing a URI domain
JT25_RS00900	COG0328	RNA-DNA hybrid ribonuclease activity
JT25_RS00905	COG2226	methyltransferase
JT25_RS00910	COG0741	lytic transglycosylase activity
JT25_RS00910	COG1388	LysM domain
JT25_RS00930	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JT25_RS00950	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JT25_RS00955	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JT25_RS00960	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JT25_RS00975	COG0446	pyridine nucleotide-disulphide oxidoreductase
JT25_RS00985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JT25_RS01025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JT25_RS01030	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JT25_RS01035	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JT25_RS01040	COG0826	peptidase U32
JT25_RS01065	COG0463	Glycosyl transferase, family 2
JT25_RS01105	COG1216	Glycosyl transferase, family 2
JT25_RS01105	COG0463	Glycosyl transferase, family 2
JT25_RS01125	COG0367	asparagine synthase
JT25_RS01160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JT25_RS01170	COG1215	transferase activity, transferring glycosyl groups
JT25_RS01190	COG1216	Glycosyl transferase, family 2
JT25_RS01195	COG0110	maltose O-acetyltransferase activity
JT25_RS01205	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JT25_RS01255	COG0326	Molecular chaperone. Has ATPase activity
JT25_RS01270	COG5001	Diguanylate cyclase
JT25_RS01270	COG3300	MHYT domain
JT25_RS01295	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JT25_RS01300	COG0497	DNA recombination
JT25_RS01305	COG0697	spore germination
JT25_RS01350	COG3293	Transposase
JT25_RS01365	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JT25_RS01370	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JT25_RS01375	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JT25_RS01380	COG2205	protein histidine kinase activity
JT25_RS01385	COG0745	RESPONSE REGULATOR receiver
JT25_RS01395	COG2151	metal-sulfur cluster biosynthetic enzyme
JT25_RS01410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JT25_RS01420	COG1696	Membrane protein involved in D-alanine export
JT25_RS01425	COG0402	S-adenosylhomocysteine deaminase activity
JT25_RS01430	COG3437	response regulator, receiver
JT25_RS01440	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JT25_RS01480	COG0583	DNA-binding transcription factor activity
JT25_RS01535	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JT25_RS01535	COG0674	pyruvate-flavodoxin oxidoreductase activity
JT25_RS01535	COG1013	pyruvate-flavodoxin oxidoreductase activity
JT25_RS01535	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JT25_RS01590	COG0330	HflC and HflK could
JT25_RS01595	COG0330	HflC and HflK could
JT25_RS01605	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JT25_RS01620	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JT25_RS01665	COG2144	transferase activity, transferring acyl groups
JT25_RS01680	COG2072	flavoprotein involved in K transport
JT25_RS01685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JT25_RS01695	COG2853	Lipoprotein
JT25_RS01700	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JT25_RS01705	COG0217	transcriptional regulatory protein
JT25_RS01720	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JT25_RS01725	COG1858	cytochrome C peroxidase
JT25_RS01740	COG4256	Hemin uptake protein
JT25_RS01775	COG3720	iron ion transport
JT25_RS01780	COG0748	coenzyme F420 binding
JT25_RS01785	COG4558	Periplasmic binding protein
JT25_RS01790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JT25_RS01795	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JT25_RS01820	COG2274	protein secretion by the type I secretion system
JT25_RS01845	COG3128	pkhd-type hydroxylase
JT25_RS01885	COG2200	EAL domain
JT25_RS01895	COG1355	regulation of microtubule-based process
JT25_RS01900	COG3885	ferrous iron binding
JT25_RS01900	COG2078	PFAM AMMECR1 domain protein
JT25_RS01905	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JT25_RS01910	COG0363	glucosamine-6-phosphate deaminase activity
JT25_RS01915	COG0129	dihydroxy-acid dehydratase activity
JT25_RS01925	COG0800	Aldolase
JT25_RS01935	COG0501	Belongs to the peptidase M48B family
JT25_RS01950	COG3852	Histidine kinase
JT25_RS01955	COG2204	response regulator
JT25_RS01960	COG5001	Diguanylate cyclase
JT25_RS01965	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JT25_RS01980	COG0483	inositol monophosphate 1-phosphatase activity
JT25_RS01985	COG0004	ammonium transporteR
JT25_RS01995	COG0004	ammonium transporteR
JT25_RS02015	COG0174	glutamine synthetase
JT25_RS02025	COG1760	l-serine dehydratase
JT25_RS02045	COG2346	COG2346, Truncated hemoglobins
JT25_RS02060	COG1451	nucleotide metabolic process
JT25_RS02065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JT25_RS02080	COG0280	phosphate acetyltransferase
JT25_RS02080	COG0857	belongs to the CobB CobQ family
JT25_RS02090	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JT25_RS02100	COG0523	cobalamin synthesis protein
JT25_RS02110	COG2193	ferroxidase activity
JT25_RS02130	COG5002	protein histidine kinase activity
JT25_RS02130	COG3447	MASE1 domain protein
JT25_RS02130	COG5001	Diguanylate cyclase
JT25_RS02135	COG2199	diguanylate cyclase activity
JT25_RS02140	COG0745	RESPONSE REGULATOR receiver
JT25_RS02145	COG3437	response regulator, receiver
JT25_RS02150	COG0343	queuine tRNA-ribosyltransferase activity
JT25_RS02155	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JT25_RS02165	COG0673	inositol 2-dehydrogenase activity
JT25_RS02195	COG2217	Heavy metal translocating P-type atpase
JT25_RS02205	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JT25_RS02215	COG2915	High frequency lysogenization protein hflD homolog
JT25_RS02220	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JT25_RS02245	COG0628	permease
JT25_RS02250	COG0586	Pfam SNARE associated Golgi protein
JT25_RS02255	COG1278	Cold shock
JT25_RS02315	COG1674	ftsk spoiiie
JT25_RS02320	COG0492	ferredoxin-NADP+ reductase activity
JT25_RS02330	COG1136	(ABC) transporter
JT25_RS02340	COG4251	negative regulation of phosphorylation
JT25_RS02345	COG5001	Diguanylate cyclase
JT25_RS02350	COG0784	Response regulator, receiver
JT25_RS02355	COG5002	protein histidine kinase activity
JT25_RS02355	COG5001	Diguanylate cyclase
JT25_RS02355	COG3447	MASE1 domain protein
JT25_RS02415	COG0513	Belongs to the DEAD box helicase family
JT25_RS02435	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JT25_RS02445	COG3108	Peptidase M15
JT25_RS02465	COG2801	Transposase and inactivated derivatives
JT25_RS02475	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
JT25_RS02490	COG4302	ethanolamine ammonia-lyase activity
JT25_RS02495	COG4303	Ethanolamine ammonia lyase large subunit
JT25_RS02500	COG2072	flavoprotein involved in K transport
JT25_RS02540	COG2801	Transposase and inactivated derivatives
JT25_RS02545	COG0582	viral genome integration into host DNA
JT25_RS02570	COG0305	Participates in initiation and elongation during chromosome replication
JT25_RS02615	COG3617	BRO family, N-terminal domain
JT25_RS02675	COG0582	viral genome integration into host DNA
JT25_RS02695	COG0659	secondary active sulfate transmembrane transporter activity
JT25_RS02700	COG0500	methyltransferase
JT25_RS02705	COG0730	response to heat
JT25_RS02710	COG2204	response regulator
JT25_RS02730	COG2132	Multicopper oxidase
JT25_RS02750	COG1294	oxidase, subunit
JT25_RS02760	COG0446	pyridine nucleotide-disulphide oxidoreductase
JT25_RS02775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JT25_RS02810	COG1028	Short-chain dehydrogenase reductase Sdr
JT25_RS02820	COG2204	response regulator
JT25_RS02835	COG0582	viral genome integration into host DNA
JT25_RS02910	COG2801	Transposase and inactivated derivatives
JT25_RS02955	COG2871	sodium ion transport
JT25_RS02975	COG2223	nitrite transmembrane transporter activity
JT25_RS02985	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JT25_RS02990	COG1140	nitrate reductase beta subunit
JT25_RS02995	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
JT25_RS03000	COG2181	nitrate reductase activity
JT25_RS03025	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JT25_RS03030	COG0384	phenazine biosynthesis protein PhzF
JT25_RS03035	COG2146	nitrite reductase [NAD(P)H] activity
JT25_RS03040	COG2146	nitrite reductase [NAD(P)H] activity
JT25_RS03040	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JT25_RS03045	COG2116	formate transmembrane transporter activity
JT25_RS03050	COG0515	serine threonine protein kinase
JT25_RS03055	COG2223	nitrite transmembrane transporter activity
JT25_RS03065	COG2815	serine threonine protein kinase
JT25_RS03065	COG0515	serine threonine protein kinase
JT25_RS03120	COG0681	Belongs to the peptidase S26 family
JT25_RS03150	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JT25_RS03155	COG2852	Protein conserved in bacteria
JT25_RS03160	COG3177	Filamentation induced by cAMP protein fic
JT25_RS03170	COG3645	SOS response
JT25_RS03210	COG0629	single-stranded DNA binding
JT25_RS03290	COG1309	transcriptional regulator
JT25_RS03295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JT25_RS03305	COG1136	(ABC) transporter
JT25_RS03305	COG0577	efflux transmembrane transporter activity
JT25_RS03315	COG0659	secondary active sulfate transmembrane transporter activity
JT25_RS03345	COG2226	methyltransferase
JT25_RS03350	COG0306	phosphate transporter
JT25_RS03360	COG0625	glutathione transferase activity
JT25_RS03375	COG0583	DNA-binding transcription factor activity
JT25_RS03420	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JT25_RS03445	COG0242	peptide deformylase activity
JT25_RS03455	COG0316	Belongs to the HesB IscA family
JT25_RS03465	COG1959	2 iron, 2 sulfur cluster binding
JT25_RS03485	COG0702	epimerase
JT25_RS03490	COG0702	epimerase
JT25_RS03500	COG0442	prolyl-tRNA aminoacylation
JT25_RS03515	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
JT25_RS03520	COG0495	leucyl-tRNA aminoacylation
JT25_RS03530	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
JT25_RS03540	COG0469	pyruvate kinase activity
JT25_RS03580	COG1525	nuclease
JT25_RS03580	COG0737	Belongs to the 5'-nucleotidase family
JT25_RS03580	COG4085	toxin activity
JT25_RS03590	COG1785	Belongs to the alkaline phosphatase family
JT25_RS03600	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JT25_RS03620	COG0798	PFAM Bile acid sodium symporter
JT25_RS03635	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
JT25_RS03640	COG3383	formate dehydrogenase (NAD+) activity
JT25_RS03645	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
JT25_RS03650	COG3259	Nickel-dependent hydrogenase
JT25_RS03660	COG1392	Phosphate transport regulator
JT25_RS03665	COG0306	phosphate transporter
JT25_RS03725	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
JT25_RS03730	COG2135	peptidase activity
JT25_RS03740	COG2826	transposase and inactivated derivatives, IS30 family
JT25_RS03800	COG2801	Transposase and inactivated derivatives
JT25_RS03885	COG3795	YCII-related domain
JT25_RS03930	COG2217	Heavy metal translocating P-type atpase
JT25_RS03970	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JT25_RS03980	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JT25_RS04000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JT25_RS04005	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JT25_RS04010	COG0542	response to heat
JT25_RS04015	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JT25_RS04025	COG0482	sulfurtransferase activity
JT25_RS04030	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JT25_RS04035	COG2715	membrane protein required for spore maturation
JT25_RS04040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JT25_RS04055	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JT25_RS04085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JT25_RS04105	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JT25_RS04115	COG2264	protein methyltransferase activity
JT25_RS04120	COG0439	Biotin carboxylase
JT25_RS04125	COG0511	ligase activity, forming carbon-carbon bonds
JT25_RS04130	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JT25_RS04135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JT25_RS04140	COG4232	protein-disulfide reductase activity
JT25_RS04145	COG1324	tolerance protein
JT25_RS04150	COG3030	protein affecting phage T7 exclusion by the F plasmid
JT25_RS04160	COG0210	DNA helicase
JT25_RS04165	COG0469	pyruvate kinase activity
JT25_RS04170	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JT25_RS04175	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JT25_RS04195	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JT25_RS04215	COG2119	membrane
JT25_RS04230	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
JT25_RS04245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JT25_RS04250	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
JT25_RS04255	COG3178	'Phosphotransferase
JT25_RS04260	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JT25_RS04265	COG1981	membrane
JT25_RS04280	COG0463	Glycosyl transferase, family 2
JT25_RS04290	COG0418	dihydroorotase activity
JT25_RS04300	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JT25_RS04305	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
JT25_RS04310	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JT25_RS04315	COG1509	lysine 2,3-aminomutase activity
JT25_RS04320	COG3437	response regulator, receiver
JT25_RS04320	COG3850	Histidine kinase
JT25_RS04320	COG4999	Histidine kinase
JT25_RS04320	COG2205	protein histidine kinase activity
JT25_RS04325	COG2203	Gaf domain
JT25_RS04325	COG3706	GGDEF domain
JT25_RS04325	COG4251	negative regulation of phosphorylation
JT25_RS04325	COG5001	Diguanylate cyclase
JT25_RS04335	COG2204	response regulator
JT25_RS04345	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JT25_RS04350	COG1381	Involved in DNA repair and RecF pathway recombination
JT25_RS04355	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JT25_RS04360	COG0571	ribonuclease III activity
JT25_RS04370	COG0681	Belongs to the peptidase S26 family
JT25_RS04375	COG0481	GTPase activity
JT25_RS04385	COG1196	nuclear chromosome segregation
JT25_RS04395	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JT25_RS04405	COG0688	phosphatidylethanolamine metabolic process
JT25_RS04410	COG1862	Preprotein translocase
JT25_RS04415	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JT25_RS04420	COG0105	UTP biosynthetic process
JT25_RS04425	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JT25_RS04435	COG0124	histidyl-tRNA synthetase
JT25_RS04445	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JT25_RS04450	COG1160	GTP binding
JT25_RS04455	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JT25_RS04495	COG1012	belongs to the aldehyde dehydrogenase family
JT25_RS04505	COG5002	protein histidine kinase activity
JT25_RS04505	COG3447	MASE1 domain protein
JT25_RS04505	COG5001	Diguanylate cyclase
JT25_RS04515	COG4191	Histidine kinase
JT25_RS04520	COG4566	intracellular signal transduction
JT25_RS04530	COG2271	Major facilitator Superfamily
JT25_RS04580	COG1525	nuclease
JT25_RS04595	COG2801	Transposase and inactivated derivatives
JT25_RS04625	COG0513	Belongs to the DEAD box helicase family
JT25_RS04635	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JT25_RS04640	COG0494	nUDIX hydrolase
JT25_RS04645	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JT25_RS04650	COG0484	heat shock protein binding
JT25_RS04655	COG0443	Heat shock 70 kDa protein
JT25_RS04660	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JT25_RS04665	COG1420	regulation of RNA biosynthetic process
JT25_RS04700	COG4191	Histidine kinase
JT25_RS04705	COG1858	cytochrome C peroxidase
JT25_RS04740	COG0149	triose-phosphate isomerase activity
JT25_RS04745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JT25_RS04765	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JT25_RS04770	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JT25_RS04775	COG0505	Belongs to the CarA family
JT25_RS04785	COG0745	RESPONSE REGULATOR receiver
JT25_RS04790	COG2205	protein histidine kinase activity
JT25_RS04815	COG2985	domain, Protein
JT25_RS04815	COG0569	domain protein
JT25_RS04845	COG0746	molybdenum cofactor guanylyltransferase activity
JT25_RS04870	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JT25_RS04875	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JT25_RS04880	COG2863	cytochrome
JT25_RS04915	COG2914	Belongs to the UPF0125 (RnfH) family
JT25_RS04930	COG4659	FMN binding
JT25_RS04935	COG4658	electron transport chain
JT25_RS04940	COG4656	Part of a membrane complex involved in electron transport
JT25_RS04945	COG2878	Part of a membrane complex involved in electron transport
JT25_RS04950	COG4657	Part of a membrane complex involved in electron transport
JT25_RS04965	COG3404	Formiminotransferase-cyclodeaminase
JT25_RS04970	COG0215	cysteine-tRNA ligase activity
JT25_RS04980	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JT25_RS04985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JT25_RS04990	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JT25_RS05000	COG1022	Amp-dependent synthetase and ligase
JT25_RS05005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JT25_RS05005	COG3320	Male sterility
JT25_RS05010	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JT25_RS05055	COG0529	Catalyzes the synthesis of activated sulfate
JT25_RS05065	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
JT25_RS05070	COG0138	bifunctional purine biosynthesis protein purh
JT25_RS05075	COG0151	Belongs to the GarS family
JT25_RS05080	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JT25_RS05095	COG2183	response to ionizing radiation
JT25_RS05105	COG0419	ATPase involved in DNA repair
JT25_RS05125	COG0438	transferase activity, transferring glycosyl groups
JT25_RS05130	COG0438	transferase activity, transferring glycosyl groups
JT25_RS05150	COG0367	asparagine synthase
JT25_RS05155	COG0438	transferase activity, transferring glycosyl groups
JT25_RS05190	COG0489	protein tyrosine kinase activity
JT25_RS05220	COG4191	Histidine kinase
JT25_RS05225	COG2204	response regulator
JT25_RS05250	COG2308	Evidence 4 Homologs of previously reported genes of
JT25_RS05270	COG1566	PFAM secretion protein HlyD family protein
JT25_RS05275	COG1538	Outer membrane efflux protein
JT25_RS05290	COG0583	DNA-binding transcription factor activity
JT25_RS05300	COG2346	COG2346, Truncated hemoglobins
JT25_RS05310	COG1686	Belongs to the peptidase S11 family
JT25_RS05320	COG2921	Belongs to the UPF0250 family
JT25_RS05325	COG0321	lipoyl(octanoyl) transferase activity
JT25_RS05330	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JT25_RS05345	COG2801	Transposase and inactivated derivatives
JT25_RS05350	COG2801	Transposase and inactivated derivatives
JT25_RS05390	COG1881	PFAM PEBP family protein
JT25_RS05400	COG3609	addiction module antidote protein, CC2985 family
JT25_RS05410	COG1204	response to ionizing radiation
JT25_RS05420	COG3609	addiction module antidote protein, CC2985 family
JT25_RS05440	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JT25_RS05470	COG2135	peptidase activity
JT25_RS05505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JT25_RS05510	COG0776	regulation of translation
JT25_RS05565	COG0210	DNA helicase
JT25_RS05635	COG4974	Belongs to the 'phage' integrase family
JT25_RS05645	COG0582	viral genome integration into host DNA
JT25_RS05650	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JT25_RS05665	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JT25_RS05685	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
JT25_RS05730	COG1543	Belongs to the glycosyl hydrolase 57 family
JT25_RS05760	COG0126	phosphoglycerate kinase activity
JT25_RS05790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JT25_RS05795	COG1309	transcriptional regulator
JT25_RS05800	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JT25_RS05800	COG1024	Enoyl-CoA hydratase
JT25_RS05805	COG4977	sequence-specific DNA binding
JT25_RS05810	COG1595	DNA-templated transcription, initiation
JT25_RS05835	COG1686	Belongs to the peptidase S11 family
JT25_RS05840	COG2900	Belongs to the SlyX family
JT25_RS05855	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JT25_RS05860	COG0590	tRNA wobble adenosine to inosine editing
JT25_RS05870	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JT25_RS05875	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JT25_RS05885	COG2226	methyltransferase
JT25_RS05895	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JT25_RS05910	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JT25_RS05930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JT25_RS05935	COG0577	efflux transmembrane transporter activity
JT25_RS05935	COG1136	(ABC) transporter
JT25_RS05955	COG1573	uracil-dna glycosylase
JT25_RS05960	COG0708	Exodeoxyribonuclease III
JT25_RS05965	COG0531	amino acid
JT25_RS05990	COG0633	Ferredoxin
JT25_RS05995	COG0426	domain, Protein
JT25_RS06015	COG0842	Transport permease protein
JT25_RS06020	COG0842	Transport permease protein
JT25_RS06025	COG1131	(ABC) transporter
JT25_RS06050	COG3706	GGDEF domain
JT25_RS06060	COG0322	excinuclease ABC activity
JT25_RS06065	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JT25_RS06065	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JT25_RS06070	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JT25_RS06075	COG2755	lipolytic protein G-D-S-L family
JT25_RS06075	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JT25_RS06085	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JT25_RS06085	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
JT25_RS06095	COG0243	molybdopterin cofactor binding
JT25_RS06140	COG5002	protein histidine kinase activity
JT25_RS06145	COG0745	RESPONSE REGULATOR receiver
JT25_RS06150	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
JT25_RS06155	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
JT25_RS06160	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JT25_RS06205	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JT25_RS06220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JT25_RS06225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JT25_RS06230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JT25_RS06240	COG2165	general secretion pathway protein
JT25_RS06245	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JT25_RS06250	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
JT25_RS06340	COG3079	Belongs to the UPF0149 family
JT25_RS06345	COG0006	proline dipeptidase activity
JT25_RS06350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JT25_RS06370	COG1253	flavin adenine dinucleotide binding
JT25_RS06375	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JT25_RS06395	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JT25_RS06440	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JT25_RS06440	COG2169	Transcriptional regulator
JT25_RS06460	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JT25_RS06465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JT25_RS06470	COG0584	glycerophosphoryl diester phosphodiesterase
JT25_RS06500	COG0741	lytic transglycosylase activity
JT25_RS06520	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JT25_RS06525	COG0305	Participates in initiation and elongation during chromosome replication
JT25_RS06530	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JT25_RS06555	COG4115	mRNA cleavage
JT25_RS06560	COG2161	toxin-antitoxin pair type II binding
JT25_RS06570	COG0309	Hydrogenase expression formation protein (HypE)
JT25_RS06580	COG0409	Hydrogenase expression formation protein
JT25_RS06595	COG0375	protein maturation
JT25_RS06600	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
JT25_RS06605	COG1773	rubredoxin
JT25_RS06615	COG1773	rubredoxin
JT25_RS06665	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
JT25_RS06685	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
JT25_RS06690	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JT25_RS06700	COG3956	TIGRFAM MazG family protein
JT25_RS06705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JT25_RS06710	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JT25_RS06715	COG0509	glycine decarboxylation via glycine cleavage system
JT25_RS06740	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JT25_RS06745	COG0543	2 iron, 2 sulfur cluster binding
JT25_RS06745	COG0493	'glutamate synthase
JT25_RS06750	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JT25_RS06755	COG1278	Cold shock
JT25_RS06760	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JT25_RS06765	COG2920	part of a sulfur-relay system
JT25_RS06780	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
JT25_RS06785	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JT25_RS06800	COG4636	protein conserved in cyanobacteria
JT25_RS06825	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JT25_RS06840	COG2346	COG2346, Truncated hemoglobins
JT25_RS06845	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JT25_RS06850	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JT25_RS06855	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JT25_RS06860	COG0501	Belongs to the peptidase M48B family
JT25_RS06865	COG1162	GTPase activity
JT25_RS06870	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JT25_RS06895	COG0537	adenosine 5'-monophosphoramidase activity
JT25_RS06900	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JT25_RS06905	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JT25_RS06920	COG0616	signal peptide processing
JT25_RS06920	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JT25_RS06930	COG0564	pseudouridine synthase activity
JT25_RS06935	COG1530	ribonuclease E activity
JT25_RS06940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JT25_RS06965	COG1222	aaa ATPase
JT25_RS07065	COG1131	(ABC) transporter
JT25_RS07070	COG0842	Transport permease protein
JT25_RS07075	COG3850	Histidine kinase
JT25_RS07075	COG4999	Histidine kinase
JT25_RS07075	COG3437	response regulator, receiver
JT25_RS07075	COG2205	protein histidine kinase activity
JT25_RS07085	COG0429	hydrolase of the alpha beta-hydrolase fold
JT25_RS07105	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JT25_RS07115	COG0519	Catalyzes the synthesis of GMP from XMP
JT25_RS07120	COG0748	coenzyme F420 binding
JT25_RS07130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JT25_RS07145	COG1739	Uncharacterized protein family UPF0029
JT25_RS07150	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JT25_RS07155	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JT25_RS07165	COG4771	TonB-dependent receptor
JT25_RS07180	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
JT25_RS07185	COG2894	cell division
JT25_RS07190	COG0850	regulation of cytokinetic process
JT25_RS07195	COG2239	Acts as a magnesium transporter
JT25_RS07200	COG1660	Displays ATPase and GTPase activities
JT25_RS07210	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JT25_RS07215	COG1137	ATPase activity
JT25_RS07220	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
JT25_RS07240	COG1127	ABC transporter
JT25_RS07245	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JT25_RS07250	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JT25_RS07260	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JT25_RS07265	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JT25_RS07270	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JT25_RS07290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JT25_RS07295	COG0723	plastoquinol--plastocyanin reductase activity
JT25_RS07300	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JT25_RS07305	COG2857	Cytochrome c1
JT25_RS07335	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JT25_RS07350	COG4585	Histidine kinase
JT25_RS07355	COG2197	response regulator
JT25_RS07380	COG0425	Belongs to the sulfur carrier protein TusA family
JT25_RS07395	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JT25_RS07400	COG0494	nUDIX hydrolase
JT25_RS07405	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
JT25_RS07410	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
JT25_RS07415	COG0237	dephospho-CoA kinase activity
JT25_RS07420	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JT25_RS07435	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JT25_RS07445	COG0142	geranyltranstransferase activity
JT25_RS07450	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JT25_RS07455	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JT25_RS07460	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JT25_RS07465	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JT25_RS07470	COG0489	protein tyrosine kinase activity
JT25_RS07475	COG1376	ErfK ybiS ycfS ynhG family protein
JT25_RS07500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JT25_RS07500	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JT25_RS07505	COG2878	Part of a membrane complex involved in electron transport
JT25_RS07515	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JT25_RS07520	COG1518	maintenance of DNA repeat elements
JT25_RS07555	COG1598	PFAM Uncharacterised protein family UPF0150
JT25_RS07560	COG1203	CRISPR-associated helicase, Cas3
JT25_RS07595	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JT25_RS07600	COG0107	imidazoleglycerol-phosphate synthase activity
JT25_RS07605	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JT25_RS07610	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JT25_RS07615	COG0131	Imidazoleglycerol-phosphate dehydratase
JT25_RS07620	COG0308	aminopeptidase N
JT25_RS07630	COG2363	Small membrane protein
JT25_RS07635	COG0521	Mo-molybdopterin cofactor biosynthetic process
JT25_RS07640	COG0628	permease
JT25_RS07650	COG0517	IMP dehydrogenase activity
JT25_RS07655	COG1451	nucleotide metabolic process
JT25_RS07695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JT25_RS07720	COG2226	methyltransferase
JT25_RS07725	COG5002	protein histidine kinase activity
JT25_RS07725	COG0784	Response regulator, receiver
JT25_RS07725	COG2198	Histidine kinase
JT25_RS07730	COG1064	alcohol dehydrogenase
JT25_RS07735	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JT25_RS07740	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JT25_RS07745	COG0742	ribosomal rna small subunit methyltransferase
JT25_RS07750	COG0612	Peptidase, M16
JT25_RS07755	COG0612	Peptidase, M16
JT25_RS07760	COG0109	protoheme IX farnesyltransferase activity
JT25_RS07765	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JT25_RS07790	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
JT25_RS07800	COG0116	Belongs to the methyltransferase superfamily
JT25_RS07800	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JT25_RS07805	COG1254	Belongs to the acylphosphatase family
JT25_RS07810	COG0181	hydroxymethylbilane synthase activity
JT25_RS07835	COG0745	RESPONSE REGULATOR receiver
JT25_RS07840	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JT25_RS07850	COG4181	ATPase activity
JT25_RS07860	COG1216	Glycosyl transferase, family 2
JT25_RS07875	COG0439	Biotin carboxylase
JT25_RS07880	COG5016	pyruvate
JT25_RS07880	COG0511	ligase activity, forming carbon-carbon bonds
JT25_RS07885	COG0009	L-threonylcarbamoyladenylate synthase
JT25_RS07905	COG0415	Belongs to the DNA photolyase family
JT25_RS07925	COG0789	Transcriptional regulator
JT25_RS07930	COG5002	protein histidine kinase activity
JT25_RS07970	COG0166	Belongs to the GPI family
JT25_RS07985	COG1238	metal cluster binding
JT25_RS08005	COG0525	valine-tRNA ligase activity
JT25_RS08015	COG0745	RESPONSE REGULATOR receiver
JT25_RS08025	COG0840	transmembrane signaling receptor activity
JT25_RS08030	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JT25_RS08055	COG1943	Transposase
JT25_RS08120	COG1215	transferase activity, transferring glycosyl groups
JT25_RS08150	COG0284	orotidine-5'-phosphate decarboxylase activity
JT25_RS08155	COG2852	Protein conserved in bacteria
JT25_RS08160	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JT25_RS08165	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JT25_RS08175	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JT25_RS08180	COG0432	Pfam Uncharacterised protein family UPF0047
JT25_RS08190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JT25_RS08195	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JT25_RS08210	COG1360	Flagellar Motor Protein
JT25_RS08230	COG1968	undecaprenyl-diphosphatase activity
JT25_RS08290	COG0642	Histidine kinase
JT25_RS08300	COG0538	isocitrate dehydrogenase activity
JT25_RS08320	COG1846	Transcriptional regulator
JT25_RS08330	COG0606	chelatase, subunit chli
JT25_RS08475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JT25_RS08495	COG0303	'Molybdopterin
JT25_RS08500	COG0583	DNA-binding transcription factor activity
JT25_RS08530	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JT25_RS08585	COG0606	chelatase, subunit chli
JT25_RS08605	COG0450	alkyl hydroperoxide reductase
JT25_RS08635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JT25_RS08650	COG0840	transmembrane signaling receptor activity
JT25_RS08655	COG0835	chemotaxis
JT25_RS08660	COG0840	transmembrane signaling receptor activity
JT25_RS08665	COG2198	Histidine kinase
JT25_RS08665	COG0643	Histidine kinase
JT25_RS08680	COG0840	transmembrane signaling receptor activity
JT25_RS08690	COG3219	Protein conserved in bacteria
JT25_RS08695	COG3220	belongs to the UPF0276 family
JT25_RS08710	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JT25_RS08720	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JT25_RS08730	COG0300	oxidoreductase activity
JT25_RS08750	COG1615	UPF0182 protein
JT25_RS08755	COG2132	Multicopper oxidase
JT25_RS08795	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JT25_RS08810	COG0457	Tetratricopeptide repeat
JT25_RS08810	COG0515	serine threonine protein kinase
JT25_RS08820	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JT25_RS08830	COG2967	ApaG domain
JT25_RS08835	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JT25_RS08845	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JT25_RS08850	COG1765	OsmC-like protein
JT25_RS08865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JT25_RS08870	COG1309	transcriptional regulator
JT25_RS08880	COG2814	Major facilitator Superfamily
JT25_RS08885	COG5002	protein histidine kinase activity
JT25_RS08900	COG3293	Transposase
JT25_RS08920	COG0583	DNA-binding transcription factor activity
JT25_RS08935	COG3293	Transposase
JT25_RS08975	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
JT25_RS09015	COG3293	Transposase
JT25_RS09020	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JT25_RS09025	COG0437	4 iron, 4 sulfur cluster binding
JT25_RS09030	COG0243	molybdopterin cofactor binding
JT25_RS09035	COG0384	phenazine biosynthesis protein PhzF
JT25_RS09040	COG2146	nitrite reductase [NAD(P)H] activity
JT25_RS09045	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JT25_RS09045	COG2146	nitrite reductase [NAD(P)H] activity
JT25_RS09050	COG2223	nitrite transmembrane transporter activity
JT25_RS09060	COG0515	serine threonine protein kinase
JT25_RS09060	COG2815	serine threonine protein kinase
JT25_RS09105	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JT25_RS09135	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JT25_RS09150	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JT25_RS09155	COG0508	dehydrogenase complex catalyzes the overall conversion of
JT25_RS09160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JT25_RS09175	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
JT25_RS09180	COG1194	a g-specific adenine glycosylase
JT25_RS09210	COG0488	(ABC) transporter
JT25_RS09220	COG0589	response to stress
JT25_RS09230	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JT25_RS09240	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JT25_RS09245	COG0778	Nitroreductase
JT25_RS09250	COG1492	cobalamin metabolic process
JT25_RS09290	COG3122	Protein conserved in bacteria
JT25_RS09295	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JT25_RS09315	COG2022	thiamine diphosphate biosynthetic process
JT25_RS09315	COG2104	thiamine diphosphate biosynthetic process
JT25_RS09320	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JT25_RS09340	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JT25_RS09350	COG4206	TonB-dependent receptor
JT25_RS09355	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
JT25_RS09360	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JT25_RS09365	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JT25_RS09370	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JT25_RS09380	COG0617	tRNA 3'-terminal CCA addition
JT25_RS09405	COG0795	lipopolysaccharide-transporting ATPase activity
JT25_RS09410	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JT25_RS09435	COG1252	NADH dehydrogenase
JT25_RS09570	COG2188	Transcriptional regulator
JT25_RS09575	COG3119	arylsulfatase activity
JT25_RS09595	COG4221	oxidoreductase activity
JT25_RS09600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JT25_RS09610	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JT25_RS09615	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JT25_RS09625	COG0778	Nitroreductase
JT25_RS09630	COG0791	NLP P60 protein
JT25_RS09645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JT25_RS09685	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JT25_RS09685	COG0519	Catalyzes the synthesis of GMP from XMP
JT25_RS09705	COG0531	amino acid
JT25_RS09725	COG2084	Dehydrogenase
JT25_RS09735	COG1166	arginine decarboxylase activity
JT25_RS09740	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JT25_RS09775	COG0577	efflux transmembrane transporter activity
JT25_RS09775	COG1136	(ABC) transporter
JT25_RS09780	COG0745	RESPONSE REGULATOR receiver
JT25_RS09785	COG2205	protein histidine kinase activity
JT25_RS09790	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JT25_RS09820	COG0577	efflux transmembrane transporter activity
JT25_RS09820	COG1136	(ABC) transporter
JT25_RS09835	COG0235	Class ii aldolase
JT25_RS09840	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
JT25_RS09845	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
JT25_RS09850	COG0189	ligase activity
JT25_RS09880	COG0179	Fumarylacetoacetate (FAA) hydrolase
JT25_RS09900	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JT25_RS09925	COG0134	indole-3-glycerol-phosphate synthase activity
JT25_RS09930	COG0730	response to heat
JT25_RS09935	COG1217	gtp-binding protein TYPA
JT25_RS09950	COG0583	DNA-binding transcription factor activity
JT25_RS09955	COG0140	phosphoribosyl-ATP diphosphatase activity
JT25_RS09960	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JT25_RS09965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JT25_RS09970	COG0805	protein transport
JT25_RS09980	COG0018	arginyl-trna synthetase
JT25_RS09995	COG0252	asparaginase activity
JT25_RS10000	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JT25_RS10015	COG0581	inorganic phosphate transmembrane transporter activity
JT25_RS10020	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JT25_RS10030	COG0784	Response regulator, receiver
JT25_RS10030	COG2205	protein histidine kinase activity
JT25_RS10030	COG5002	protein histidine kinase activity
JT25_RS10040	COG4771	TonB-dependent receptor
JT25_RS10085	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JT25_RS10090	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JT25_RS10095	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JT25_RS10100	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JT25_RS10115	COG0456	acetyltransferase
JT25_RS10120	COG0752	glycyl-tRNA synthetase alpha subunit
JT25_RS10125	COG0751	glycine-tRNA ligase activity
JT25_RS10130	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JT25_RS10155	COG0646	methionine synthase
JT25_RS10155	COG1410	methionine synthase
JT25_RS10195	COG2273	Hydrolase Family 16
JT25_RS10195	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
JT25_RS10200	COG2274	protein secretion by the type I secretion system
JT25_RS10210	COG3547	Transposase (IS116 IS110 IS902 family)
JT25_RS10215	COG3547	Transposase (IS116 IS110 IS902 family)
JT25_RS10220	COG2826	transposase and inactivated derivatives, IS30 family
JT25_RS10255	COG2954	triphosphatase activity
JT25_RS10260	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JT25_RS10270	COG0625	glutathione transferase activity
JT25_RS10290	COG0196	riboflavin kinase activity
JT25_RS10305	COG0154	amidase activity
JT25_RS10310	COG4521	taurine ABC transporter
JT25_RS10315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JT25_RS10320	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
JT25_RS10335	COG3293	Transposase
JT25_RS10350	COG3328	transposase activity
JT25_RS10405	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JT25_RS10410	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JT25_RS10420	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JT25_RS10430	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JT25_RS10435	COG0792	nuclease activity
JT25_RS10440	COG3107	peptidoglycan biosynthetic process
JT25_RS10445	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JT25_RS10500	COG4319	ketosteroid isomerase
JT25_RS10625	COG4319	ketosteroid isomerase
JT25_RS10635	COG0730	response to heat
JT25_RS10650	COG0523	cobalamin synthesis protein
JT25_RS10665	COG0789	Transcriptional regulator
JT25_RS10695	COG0187	DNA topoisomerase II activity
JT25_RS10700	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JT25_RS10710	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JT25_RS10725	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JT25_RS10740	COG4115	mRNA cleavage
JT25_RS10750	COG1322	Protein conserved in bacteria
JT25_RS10785	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JT25_RS10795	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JT25_RS10795	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JT25_RS10800	COG1393	Belongs to the ArsC family
JT25_RS10835	COG3795	YCII-related domain
JT25_RS10850	COG3795	YCII-related domain
JT25_RS10855	COG3012	SEC-C Motif Domain Protein
JT25_RS10875	COG4941	Belongs to the sigma-70 factor family
JT25_RS10885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JT25_RS10905	COG3045	CreA protein
JT25_RS10910	COG4999	Histidine kinase
JT25_RS10910	COG3850	Histidine kinase
JT25_RS10910	COG3437	response regulator, receiver
JT25_RS10910	COG2205	protein histidine kinase activity
JT25_RS10925	COG0656	L-ascorbic acid biosynthetic process
JT25_RS10930	COG5002	protein histidine kinase activity
JT25_RS10930	COG2205	protein histidine kinase activity
JT25_RS10930	COG0784	Response regulator, receiver
JT25_RS10935	COG3437	response regulator, receiver
JT25_RS10960	COG0745	RESPONSE REGULATOR receiver
JT25_RS10965	COG1067	ATP-dependent peptidase activity
JT25_RS10970	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JT25_RS10970	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JT25_RS10980	COG0445	tRNA wobble uridine modification
JT25_RS10985	COG0357	Ribosomal RNA small subunit methyltransferase G
JT25_RS10990	COG1192	Involved in chromosome partitioning
JT25_RS10995	COG1475	DNA binding
JT25_RS11005	COG0356	it plays a direct role in the translocation of protons across the membrane
JT25_RS11015	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JT25_RS11020	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JT25_RS11025	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JT25_RS11030	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JT25_RS11035	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JT25_RS11040	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JT25_RS11045	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JT25_RS11050	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JT25_RS11080	COG1278	Cold shock
JT25_RS11120	COG0438	transferase activity, transferring glycosyl groups
JT25_RS11130	COG2197	response regulator
JT25_RS11165	COG1215	transferase activity, transferring glycosyl groups
JT25_RS11175	COG0038	chloride channel
JT25_RS11180	COG0475	glutathione-regulated potassium exporter activity
JT25_RS11180	COG0569	domain protein
JT25_RS11200	COG3706	GGDEF domain
JT25_RS11205	COG3100	YcgL domain-containing protein
JT25_RS11205	COG0561	phosphatase activity
JT25_RS11210	COG0438	transferase activity, transferring glycosyl groups
JT25_RS11220	COG0745	RESPONSE REGULATOR receiver
JT25_RS11225	COG0642	Histidine kinase
JT25_RS11230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JT25_RS11270	COG0583	DNA-binding transcription factor activity
JT25_RS11300	COG3547	Transposase (IS116 IS110 IS902 family)
JT25_RS11305	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JT25_RS11320	COG2801	Transposase and inactivated derivatives
JT25_RS11345	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
JT25_RS11350	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JT25_RS11355	COG1028	Short-chain dehydrogenase reductase Sdr
JT25_RS11370	COG3220	belongs to the UPF0276 family
JT25_RS11390	COG1943	Transposase
JT25_RS11410	COG0625	glutathione transferase activity
JT25_RS11465	COG0484	heat shock protein binding
JT25_RS11510	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
JT25_RS11525	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JT25_RS11530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JT25_RS11530	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JT25_RS11535	COG1056	cytidyltransferase-related domain
JT25_RS11535	COG1051	belongs to the nudix hydrolase family
JT25_RS11540	COG3530	Putative quorum-sensing-regulated virulence factor
JT25_RS11550	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JT25_RS11560	COG3706	GGDEF domain
JT25_RS11600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JT25_RS11605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JT25_RS11610	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JT25_RS11615	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JT25_RS11620	COG0189	ligase activity
JT25_RS11630	COG1678	Uncharacterized ACR, COG1678
JT25_RS11635	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JT25_RS11640	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JT25_RS11645	COG0540	Belongs to the ATCase OTCase family
JT25_RS11660	COG0714	Associated with various cellular activities
JT25_RS11690	COG1253	flavin adenine dinucleotide binding
JT25_RS11710	COG0494	nUDIX hydrolase
JT25_RS11715	COG0840	transmembrane signaling receptor activity
JT25_RS11720	COG1011	Hydrolase
JT25_RS11740	COG4178	(ABC) transporter
JT25_RS11755	COG0314	molybdopterin synthase activity
JT25_RS11760	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JT25_RS11765	COG0315	cyclic pyranopterin monophosphate synthase activity
JT25_RS11785	COG1530	ribonuclease E activity
JT25_RS11790	COG0424	maF-like protein
JT25_RS11795	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JT25_RS11800	COG5001	Diguanylate cyclase
JT25_RS11800	COG5002	protein histidine kinase activity
JT25_RS11810	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JT25_RS11820	COG3002	Belongs to the UPF0753 family
JT25_RS11840	COG0288	reversible hydration of carbon dioxide
JT25_RS11845	COG0659	secondary active sulfate transmembrane transporter activity
JT25_RS11855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JT25_RS11855	COG2205	protein histidine kinase activity
JT25_RS11865	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JT25_RS11870	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JT25_RS11880	COG1561	YicC-like family, N-terminal region
JT25_RS11895	COG1902	pentaerythritol trinitrate reductase activity
JT25_RS11905	COG3300	MHYT domain
JT25_RS11905	COG5001	Diguanylate cyclase
JT25_RS11930	COG4636	protein conserved in cyanobacteria
JT25_RS11945	COG0330	HflC and HflK could
JT25_RS11965	COG0714	Associated with various cellular activities
JT25_RS11985	COG2951	lytic endotransglycosylase activity
JT25_RS11995	COG2801	Transposase and inactivated derivatives
JT25_RS12015	COG1192	Involved in chromosome partitioning
JT25_RS12035	COG3028	Belongs to the UPF0307 family
JT25_RS12045	COG2974	May be involved in recombination
JT25_RS12050	COG1376	ErfK ybiS ycfS ynhG family protein
JT25_RS12050	COG1388	LysM domain
JT25_RS12065	COG0033	Phosphoglucomutase
JT25_RS12075	COG1278	Cold shock
JT25_RS12100	COG2373	Large extracellular alpha-helical protein
JT25_RS12110	COG1301	dicarboxylic acid transport
JT25_RS12195	COG0463	Glycosyl transferase, family 2
JT25_RS12215	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
JT25_RS12230	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JT25_RS12235	COG1181	Belongs to the D-alanine--D-alanine ligase family
JT25_RS12240	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JT25_RS12245	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JT25_RS12250	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JT25_RS12255	COG0772	Belongs to the SEDS family
JT25_RS12260	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JT25_RS12265	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JT25_RS12270	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JT25_RS12285	COG3116	cell division
JT25_RS12295	COG2001	Belongs to the MraZ family
JT25_RS12300	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JT25_RS12305	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
JT25_RS12315	COG0640	Transcriptional regulator
JT25_RS12320	COG4942	peptidase
JT25_RS12325	COG0793	Belongs to the peptidase S41A family
JT25_RS12340	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JT25_RS12345	COG2223	nitrite transmembrane transporter activity
JT25_RS12380	COG0019	diaminopimelate decarboxylase activity
JT25_RS12385	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JT25_RS12425	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JT25_RS12480	COG0631	protein serine/threonine phosphatase activity
JT25_RS12555	COG3209	COG3209 Rhs family protein
JT25_RS12585	COG3209	COG3209 Rhs family protein
JT25_RS12590	COG1454	alcohol dehydrogenase
JT25_RS12595	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JT25_RS12610	COG0339	signal peptide processing
JT25_RS12630	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JT25_RS12645	COG2854	intermembrane phospholipid transfer
JT25_RS12650	COG4106	trans-aconitate 2-methyltransferase activity
JT25_RS12655	COG0500	methyltransferase
JT25_RS12660	COG1555	photosystem II stabilization
JT25_RS12670	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JT25_RS12685	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JT25_RS12695	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JT25_RS12700	COG0191	fructose-bisphosphate aldolase activity
JT25_RS12705	COG1580	Controls the rotational direction of flagella during chemotaxis
JT25_RS12735	COG1684	flagellar biosynthetic protein fliR
JT25_RS12770	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
JT25_RS12775	COG0643	Histidine kinase
JT25_RS12775	COG0784	Response regulator, receiver
JT25_RS12775	COG2198	Histidine kinase
JT25_RS12785	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JT25_RS12795	COG1192	Involved in chromosome partitioning
JT25_RS12805	COG0835	chemotaxis
JT25_RS12835	COG0859	PFAM glycosyl transferase family 9
JT25_RS12840	COG1132	(ABC) transporter
JT25_RS12845	COG0535	radical SAM domain protein
JT25_RS12865	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JT25_RS12870	COG0730	response to heat
JT25_RS12875	COG0617	tRNA 3'-terminal CCA addition
JT25_RS12885	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
JT25_RS12895	COG0312	modulator of DNA gyrase
JT25_RS12900	COG0312	modulator of DNA gyrase
JT25_RS12905	COG0167	dihydroorotate dehydrogenase activity
JT25_RS12935	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JT25_RS12970	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JT25_RS12975	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JT25_RS12980	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JT25_RS12990	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JT25_RS12995	COG1610	YqeY-like protein
JT25_RS13000	COG0358	DNA primase activity
JT25_RS13015	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JT25_RS13020	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JT25_RS13030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JT25_RS13045	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JT25_RS13065	COG0356	it plays a direct role in the translocation of protons across the membrane
JT25_RS13075	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JT25_RS13075	COG2755	lipolytic protein G-D-S-L family
JT25_RS13080	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JT25_RS13080	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JT25_RS13085	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JT25_RS13105	COG2204	response regulator
JT25_RS13110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JT25_RS13120	COG2132	Multicopper oxidase
JT25_RS13145	COG0784	Response regulator, receiver
JT25_RS13145	COG2205	protein histidine kinase activity
JT25_RS13145	COG5002	protein histidine kinase activity
JT25_RS13195	COG0583	DNA-binding transcription factor activity
JT25_RS13200	COG0596	Alpha beta hydrolase
JT25_RS13250	COG0837	glucose binding
JT25_RS13260	COG0717	Belongs to the dCTP deaminase family
JT25_RS13280	COG3391	amine dehydrogenase activity
JT25_RS13300	COG1858	cytochrome C peroxidase
JT25_RS13315	COG5001	Diguanylate cyclase
JT25_RS13315	COG5002	protein histidine kinase activity
JT25_RS13315	COG3447	MASE1 domain protein
JT25_RS13325	COG1294	oxidase, subunit
JT25_RS13335	COG1546	Belongs to the CinA family
JT25_RS13345	COG0501	Belongs to the peptidase M48B family
JT25_RS13355	COG2171	N-acyltransferase activity
JT25_RS13380	COG1393	Belongs to the ArsC family
JT25_RS13385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JT25_RS13400	COG2003	Belongs to the UPF0758 family
JT25_RS13405	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JT25_RS13410	COG0756	dUTP diphosphatase activity
JT25_RS13420	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JT25_RS13440	COG0728	peptidoglycan biosynthetic process
JT25_RS13445	COG0268	Binds directly to 16S ribosomal RNA
JT25_RS13465	COG0542	response to heat
JT25_RS13470	COG1278	Cold shock
JT25_RS13495	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
JT25_RS13500	COG1229	Formylmethanofuran dehydrogenase subunit A
JT25_RS13510	COG2154	pterin-4-alpha-carbinolamine dehydratase
JT25_RS13515	COG2969	positive regulation of protein catabolic process
JT25_RS13520	COG0625	glutathione transferase activity
JT25_RS13530	COG0306	phosphate transporter
JT25_RS13540	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JT25_RS13545	COG0594	ribonuclease P activity
JT25_RS13550	COG0706	membrane insertase activity
JT25_RS13555	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JT25_RS13635	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JT25_RS13650	COG3086	response to oxidative stress
JT25_RS13665	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JT25_RS13670	COG4206	TonB-dependent receptor
JT25_RS13690	COG4251	negative regulation of phosphorylation
JT25_RS13690	COG3706	GGDEF domain
JT25_RS13690	COG2203	Gaf domain
JT25_RS13690	COG5001	Diguanylate cyclase
JT25_RS13710	COG1666	GTP binding
JT25_RS13725	COG0433	COG0433 Predicted ATPase
JT25_RS13765	COG0175	sulfate reduction
JT25_RS13785	COG0501	Belongs to the peptidase M48B family
JT25_RS13810	COG0514	ATP-dependent DNA helicase (RecQ)
JT25_RS13815	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JT25_RS13825	COG0154	amidase activity
JT25_RS13830	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JT25_RS13835	COG1077	Cell shape determining protein MreB Mrl
JT25_RS13840	COG1792	Involved in formation and maintenance of cell shape
JT25_RS13845	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JT25_RS13850	COG0768	penicillin binding
JT25_RS13855	COG0772	Belongs to the SEDS family
JT25_RS13860	COG2951	lytic endotransglycosylase activity
JT25_RS13875	COG1716	ATPase activity
JT25_RS13890	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JT25_RS13900	COG3951	Flagellar rod assembly protein muramidase FlgJ
JT25_RS13900	COG1705	Flagellar rod assembly protein muramidase FlgJ
JT25_RS13905	COG1706	bacterial-type flagellum-dependent cell motility
JT25_RS13910	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
JT25_RS13915	COG4786	Flagellar basal body rod
JT25_RS13920	COG4787	bacterial-type flagellum-dependent cell motility
JT25_RS13930	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JT25_RS13940	COG1815	bacterial-type flagellum-dependent cell motility
JT25_RS13945	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JT25_RS13950	COG0835	chemotaxis
JT25_RS13950	COG0784	Response regulator, receiver
JT25_RS14030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JT25_RS14040	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JT25_RS14045	COG0473	3-isopropylmalate dehydrogenase activity
JT25_RS14050	COG0066	3-isopropylmalate dehydratase activity
JT25_RS14055	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JT25_RS14060	COG0563	adenylate kinase activity
JT25_RS14070	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JT25_RS14080	COG2010	Cytochrome c
JT25_RS14085	COG2863	cytochrome
JT25_RS14120	COG0535	radical SAM domain protein
JT25_RS14135	COG0316	Belongs to the HesB IscA family
JT25_RS14140	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JT25_RS14150	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JT25_RS14185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JT25_RS14195	COG0217	transcriptional regulatory protein
JT25_RS14200	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JT25_RS14205	COG0632	four-way junction helicase activity
JT25_RS14210	COG2255	four-way junction helicase activity
JT25_RS14215	COG0824	Thioesterase
JT25_RS14235	COG0823	Involved in the tonB-independent uptake of proteins
JT25_RS14240	COG2885	chlorophyll binding
JT25_RS14245	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
JT25_RS14250	COG0602	queuosine metabolic process
JT25_RS14255	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JT25_RS14270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JT25_RS14275	COG1702	phosphate starvation-inducible protein PhoH
JT25_RS14285	COG4535	Mg2 and Co2 transporter CorC
JT25_RS14295	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JT25_RS14305	COG0297	glycogen (starch) synthase activity
JT25_RS14310	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JT25_RS14315	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JT25_RS14340	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JT25_RS14345	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JT25_RS14380	COG0483	inositol monophosphate 1-phosphatase activity
JT25_RS14395	COG0288	reversible hydration of carbon dioxide
JT25_RS14400	COG0659	secondary active sulfate transmembrane transporter activity
JT25_RS14420	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JT25_RS14430	COG3384	dioxygenase
JT25_RS14435	COG1067	ATP-dependent peptidase activity
JT25_RS14440	COG0116	Belongs to the methyltransferase superfamily
JT25_RS14440	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JT25_RS14455	COG0542	response to heat
JT25_RS14485	COG1487	ribonuclease activity
JT25_RS14490	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JT25_RS14510	COG2307	Protein conserved in bacteria
JT25_RS14510	COG2308	Evidence 4 Homologs of previously reported genes of
JT25_RS14515	COG2308	Evidence 4 Homologs of previously reported genes of
JT25_RS14535	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JT25_RS14535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JT25_RS14540	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JT25_RS14545	COG0045	succinate-CoA ligase (ADP-forming) activity
JT25_RS14565	COG5001	Diguanylate cyclase
JT25_RS14565	COG5002	protein histidine kinase activity
JT25_RS14575	COG3746	phosphate-selective porin O and P
JT25_RS14580	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JT25_RS14590	COG2890	protein-(glutamine-N5) methyltransferase activity
JT25_RS14595	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JT25_RS14600	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JT25_RS14610	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
JT25_RS14615	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JT25_RS14625	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JT25_RS14630	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JT25_RS14635	COG0193	aminoacyl-tRNA hydrolase activity
JT25_RS14655	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JT25_RS14665	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JT25_RS14675	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JT25_RS14680	COG0081	regulation of translation
JT25_RS14685	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JT25_RS14690	COG0222	ribosome binding
JT25_RS14695	COG0085	RNA polymerase activity
JT25_RS14700	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JT25_RS14710	COG0049	tRNA binding
JT25_RS14715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JT25_RS14720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JT25_RS14725	COG0051	transcription antitermination factor activity, RNA binding
JT25_RS14730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JT25_RS14735	COG0088	Forms part of the polypeptide exit tunnel
JT25_RS14740	COG0089	rRNA binding
JT25_RS14745	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JT25_RS14750	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JT25_RS14755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JT25_RS14760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JT25_RS14765	COG0255	Belongs to the universal ribosomal protein uL29 family
JT25_RS14770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JT25_RS14775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JT25_RS14780	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JT25_RS14790	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JT25_RS14795	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JT25_RS14800	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JT25_RS14805	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JT25_RS14810	COG1841	ribosomal large subunit assembly
JT25_RS14815	COG0200	Binds to the 23S rRNA
JT25_RS14820	COG0201	protein transport
JT25_RS14825	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JT25_RS14830	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JT25_RS14835	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JT25_RS14845	COG0203	ribosomal protein L17
JT25_RS14855	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JT25_RS14860	COG2840	Smr protein MutS2
JT25_RS14865	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JT25_RS14870	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JT25_RS14880	COG0443	Heat shock 70 kDa protein
JT25_RS14885	COG0535	radical SAM domain protein
JT25_RS14890	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JT25_RS14895	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JT25_RS14900	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JT25_RS14900	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JT25_RS14905	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JT25_RS14910	COG0022	dehydrogenase e1 component
JT25_RS14930	COG1032	radical SAM domain protein
JT25_RS14970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JT25_RS14975	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JT25_RS14980	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JT25_RS14985	COG2089	acid synthase
JT25_RS15000	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JT25_RS15010	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JT25_RS15015	COG1516	flagellar protein fliS
JT25_RS15025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JT25_RS15035	COG4137	Cytochrome C assembly protein
JT25_RS15040	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JT25_RS15045	COG0228	four-way junction DNA binding
JT25_RS15050	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JT25_RS15060	COG0335	large ribosomal subunit rRNA binding
JT25_RS15070	COG4974	Belongs to the 'phage' integrase family
JT25_RS15075	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JT25_RS15090	COG5001	Diguanylate cyclase
JT25_RS15090	COG5002	protein histidine kinase activity
JT25_RS15100	COG1362	aminopeptidase activity
JT25_RS15105	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JT25_RS15110	COG0446	pyridine nucleotide-disulphide oxidoreductase
JT25_RS15125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JT25_RS15165	COG3411	Ferredoxin
JT25_RS15190	COG0247	lactate metabolic process
JT25_RS15210	COG1596	polysaccharide export
JT25_RS15215	COG3206	protein involved in exopolysaccharide biosynthesis
JT25_RS15215	COG0489	protein tyrosine kinase activity
JT25_RS15300	COG0515	serine threonine protein kinase
JT25_RS15300	COG2815	serine threonine protein kinase
JT25_RS15345	COG1943	Transposase
JT25_RS15360	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JT25_RS15385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JT25_RS15390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JT25_RS15395	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JT25_RS15400	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JT25_RS15405	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JT25_RS15420	COG0084	hydrolase, TatD family'
JT25_RS15425	COG2813	Specifically methylates the guanine in position
JT25_RS15435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JT25_RS15440	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JT25_RS15460	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JT25_RS15465	COG1657	PFAM Prenyltransferase squalene oxidase
JT25_RS15470	COG1562	ergosterol biosynthetic process
JT25_RS15475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JT25_RS15485	COG2853	Lipoprotein
JT25_RS15490	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JT25_RS15495	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JT25_RS15500	COG0142	geranyltranstransferase activity
JT25_RS15505	COG1722	exodeoxyribonuclease VII activity
JT25_RS15555	COG2918	glutathione biosynthetic process
JT25_RS15570	COG0514	ATP-dependent DNA helicase (RecQ)
JT25_RS15595	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JT25_RS15600	COG1132	(ABC) transporter
JT25_RS15605	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JT25_RS15610	COG0745	RESPONSE REGULATOR receiver
JT25_RS15615	COG0642	Histidine kinase
JT25_RS15620	COG0288	reversible hydration of carbon dioxide
JT25_RS15630	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JT25_RS15635	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JT25_RS15650	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JT25_RS15680	COG5002	protein histidine kinase activity
JT25_RS15680	COG0784	Response regulator, receiver
JT25_RS15680	COG2205	protein histidine kinase activity
JT25_RS15695	COG2133	pyrroloquinoline quinone binding
JT25_RS15700	COG0494	nUDIX hydrolase
JT25_RS15710	COG0501	Belongs to the peptidase M48B family
JT25_RS15720	COG0753	catalase activity
JT25_RS15750	COG1902	pentaerythritol trinitrate reductase activity
JT25_RS15755	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JT25_RS15760	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JT25_RS15765	COG0799	negative regulation of ribosome biogenesis
JT25_RS15780	COG0386	Belongs to the glutathione peroxidase family
JT25_RS15860	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JT25_RS15865	COG0825	malonyl-CoA metabolic process
JT25_RS15870	COG0037	tRNA processing
JT25_RS15890	COG0504	CTP synthase activity
JT25_RS15895	COG2877	3-deoxy-8-phosphooctulonate synthase activity
JT25_RS15900	COG0148	phosphopyruvate hydratase activity
JT25_RS15905	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JT25_RS15910	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JT25_RS15915	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JT25_RS15925	COG0585	pseudouridine synthase activity
JT25_RS15945	COG1538	Outer membrane efflux protein
JT25_RS15955	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JT25_RS15960	COG3383	formate dehydrogenase (NAD+) activity
JT25_RS15975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JT25_RS15985	COG2350	Protein conserved in bacteria
JT25_RS15990	COG2917	probably involved in intracellular septation
JT25_RS16025	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JT25_RS16030	COG1785	Belongs to the alkaline phosphatase family
JT25_RS16050	COG1573	uracil-dna glycosylase
JT25_RS16055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JT25_RS16065	COG1183	phosphatidylcholine synthase activity
JT25_RS16075	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JT25_RS16085	COG0028	Belongs to the TPP enzyme family
JT25_RS16090	COG2091	lysine biosynthetic process via aminoadipic acid
JT25_RS16100	COG2197	response regulator
JT25_RS16105	COG3851	Histidine kinase
JT25_RS16120	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JT25_RS16125	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JT25_RS16130	COG2204	response regulator
JT25_RS16135	COG5000	phosphorelay sensor kinase activity
JT25_RS16150	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JT25_RS16155	COG0242	peptide deformylase activity
JT25_RS16160	COG1652	LysM domain
JT25_RS16165	COG0758	DNA mediated transformation
JT25_RS16170	COG2922	Belongs to the Smg family
JT25_RS16190	COG0544	peptidyl-prolyl cis-trans isomerase activity
JT25_RS16195	COG0740	serine-type endopeptidase activity
JT25_RS16200	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JT25_RS16205	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JT25_RS16210	COG0776	regulation of translation
JT25_RS16235	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JT25_RS16245	COG4174	ABC transporter (Permease)
JT25_RS16250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JT25_RS16255	COG4172	Belongs to the ABC transporter superfamily
JT25_RS16275	COG2204	response regulator
JT25_RS16280	COG3852	Histidine kinase
JT25_RS16290	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JT25_RS16290	COG0392	lysyltransferase activity
JT25_RS16300	COG2267	carboxylic ester hydrolase activity
JT25_RS16340	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JT25_RS16345	COG3338	carbonate dehydratase activity
JT25_RS16360	COG0659	secondary active sulfate transmembrane transporter activity
JT25_RS16365	COG3002	Belongs to the UPF0753 family
JT25_RS16375	COG2824	Alkylphosphonate utilization operon protein PhnA
JT25_RS16380	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JT25_RS16400	COG2204	response regulator
JT25_RS16405	COG3852	Histidine kinase
JT25_RS16415	COG0004	ammonium transporteR
JT25_RS16445	COG1301	dicarboxylic acid transport
JT25_RS16455	COG3104	oligopeptide transport
JT25_RS16460	COG0281	malic enzyme
JT25_RS16490	COG1882	Formate acetyltransferase
JT25_RS16500	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JT25_RS16510	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JT25_RS16530	COG2205	protein histidine kinase activity
JT25_RS16535	COG0745	RESPONSE REGULATOR receiver
JT25_RS16545	COG0754	glutathionylspermidine amidase activity
JT25_RS16555	COG2116	formate transmembrane transporter activity
JT25_RS16560	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
JT25_RS16565	COG0515	serine threonine protein kinase
JT25_RS16565	COG2815	serine threonine protein kinase
JT25_RS16605	COG0488	(ABC) transporter
JT25_RS16645	COG1566	PFAM secretion protein HlyD family protein
JT25_RS16655	COG1846	Transcriptional regulator
JT25_RS16665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JT25_RS16690	COG0653	protein targeting
JT25_RS16695	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JT25_RS16705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JT25_RS16725	COG0415	Belongs to the DNA photolyase family
JT25_RS16735	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JT25_RS16740	COG0830	nickel cation binding
JT25_RS16745	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
JT25_RS16760	COG0804	urea catabolic process
JT25_RS16765	COG0832	Belongs to the urease beta subunit family
JT25_RS16770	COG0831	urea catabolic process
JT25_RS16775	COG2161	toxin-antitoxin pair type II binding
JT25_RS16780	COG4115	mRNA cleavage
JT25_RS16795	COG0829	nickel cation binding
JT25_RS16825	COG0559	Belongs to the binding-protein-dependent transport system permease family
JT25_RS16860	COG2205	protein histidine kinase activity
JT25_RS16860	COG0784	Response regulator, receiver
JT25_RS16875	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JT25_RS16880	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JT25_RS16885	COG0416	fatty acid biosynthetic process
JT25_RS16890	COG1399	metal-binding, possibly nucleic acid-binding protein
JT25_RS16895	COG0424	maF-like protein
JT25_RS16905	COG0741	lytic transglycosylase activity
JT25_RS16910	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JT25_RS16915	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JT25_RS16920	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JT25_RS16925	COG0302	gtp cyclohydrolase
JT25_RS16930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JT25_RS16950	COG0784	Response regulator, receiver
JT25_RS16950	COG2205	protein histidine kinase activity
JT25_RS16950	COG5002	protein histidine kinase activity
JT25_RS16960	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JT25_RS16965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JT25_RS16975	COG3293	Transposase
JT25_RS17015	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JT25_RS17015	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JT25_RS17020	COG0802	atpase or kinase
JT25_RS17025	COG0860	N-Acetylmuramoyl-L-alanine amidase
JT25_RS17030	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JT25_RS17035	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JT25_RS17040	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JT25_RS17045	COG0019	diaminopimelate decarboxylase activity
JT25_RS17065	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JT25_RS17070	COG0084	hydrolase, TatD family'
JT25_RS17075	COG0488	(ABC) transporter
JT25_RS17080	COG1923	regulation of RNA biosynthetic process
JT25_RS17085	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JT25_RS17090	COG0330	HflC and HflK could
JT25_RS17095	COG0330	HflC and HflK could
JT25_RS17100	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JT25_RS17105	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JT25_RS17120	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JT25_RS17155	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JT25_RS17180	COG0360	Binds together with S18 to 16S ribosomal RNA
JT25_RS17185	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JT25_RS17195	COG0359	binds to the 23S rRNA
JT25_RS17200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JT25_RS17215	COG0574	Belongs to the PEP-utilizing enzyme family
JT25_RS17215	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JT25_RS17225	COG1519	Transferase
JT25_RS17230	COG0137	argininosuccinate synthase activity
JT25_RS17245	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JT25_RS17245	COG1648	precorrin-2 dehydrogenase activity
JT25_RS17250	COG0425	Belongs to the sulfur carrier protein TusA family
JT25_RS17260	COG0494	nUDIX hydrolase
JT25_RS17270	COG1051	belongs to the nudix hydrolase family
JT25_RS17275	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JT25_RS17275	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JT25_RS17290	COG0129	dihydroxy-acid dehydratase activity
JT25_RS17300	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JT25_RS17305	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JT25_RS17320	COG2376	Dihydroxyacetone kinase
JT25_RS17325	COG0647	UMP catabolic process
JT25_RS17340	COG0779	Required for maturation of 30S ribosomal subunits
JT25_RS17345	COG0195	Participates in both transcription termination and antitermination
JT25_RS17350	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JT25_RS17360	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JT25_RS17365	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JT25_RS17370	COG1185	polyribonucleotide nucleotidyltransferase activity
JT25_RS17380	COG2153	protein acetylation
JT25_RS17390	COG1573	uracil-dna glycosylase
JT25_RS17395	COG0322	excinuclease ABC activity
JT25_RS17400	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JT25_RS17410	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JT25_RS17420	COG3119	arylsulfatase activity
JT25_RS17435	COG0726	polysaccharide deacetylase
JT25_RS17440	COG1959	2 iron, 2 sulfur cluster binding
JT25_RS17445	COG0719	Fe-S assembly protein
JT25_RS17450	COG0396	ATPase activity
JT25_RS17455	COG0719	Fe-S assembly protein
JT25_RS17465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JT25_RS17475	COG0742	ribosomal rna small subunit methyltransferase
JT25_RS17485	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JT25_RS17495	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JT25_RS17510	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JT25_RS17515	COG2515	1-aminocyclopropane-1-carboxylate deaminase
JT25_RS17525	COG3360	Dodecin
JT25_RS17530	COG0352	thiamine-phosphate diphosphorylase activity
JT25_RS17535	COG0351	phosphomethylpyrimidine kinase
JT25_RS17540	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JT25_RS17545	COG0735	belongs to the Fur family
JT25_RS17550	COG2203	Gaf domain
JT25_RS17550	COG5001	Diguanylate cyclase
JT25_RS17550	COG3706	GGDEF domain
JT25_RS17550	COG4251	negative regulation of phosphorylation
JT25_RS17555	COG0574	Belongs to the PEP-utilizing enzyme family
JT25_RS17555	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JT25_RS17560	COG2081	HI0933 family
JT25_RS17570	COG0372	Belongs to the citrate synthase family
JT25_RS17580	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
JT25_RS17585	COG1053	succinate dehydrogenase
JT25_RS17590	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JT25_RS17595	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
JT25_RS17600	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JT25_RS17635	COG0745	RESPONSE REGULATOR receiver
JT25_RS17640	COG2198	Histidine kinase
JT25_RS17640	COG0643	Histidine kinase
JT25_RS17650	COG0840	transmembrane signaling receptor activity
JT25_RS17650	COG0840	transmembrane signaling receptor activity
JT25_RS17655	COG0835	chemotaxis
JT25_RS17660	COG1192	Involved in chromosome partitioning
JT25_RS17670	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JT25_RS17675	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
JT25_RS17680	COG2201	protein-glutamate methylesterase activity
JT25_RS17685	COG0840	transmembrane signaling receptor activity
JT25_RS17700	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JT25_RS17715	COG1199	ATP-dependent helicase activity
JT25_RS17720	COG1214	PFAM Peptidase M22, glycoprotease
JT25_RS17725	COG0009	L-threonylcarbamoyladenylate synthase
JT25_RS17730	COG1994	Peptidase M50
JT25_RS17740	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JT25_RS17745	COG1187	pseudouridine synthase activity
JT25_RS17755	COG0587	DNA-directed DNA polymerase activity
JT25_RS17770	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JT25_RS17775	COG0745	RESPONSE REGULATOR receiver
JT25_RS17800	COG1546	Belongs to the CinA family
JT25_RS17800	COG1058	Belongs to the CinA family
JT25_RS17805	COG0488	(ABC) transporter
JT25_RS17875	COG2165	general secretion pathway protein
JT25_RS17910	COG2831	hemolysin activation secretion protein
JT25_RS17920	COG0811	peptide transport
JT25_RS17965	COG1596	polysaccharide export
JT25_RS17970	COG3293	Transposase
JT25_RS17985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JT25_RS17990	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JT25_RS17995	COG3123	guanosine phosphorylase activity
JT25_RS18005	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JT25_RS18010	COG0735	belongs to the Fur family
JT25_RS18020	COG1136	(ABC) transporter
JT25_RS18040	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JT25_RS18050	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JT25_RS18055	COG0039	L-malate dehydrogenase activity
JT25_RS18065	COG1216	Glycosyl transferase, family 2
JT25_RS18065	COG1442	glycosyl transferase family 8
JT25_RS18070	COG0367	asparagine synthase
JT25_RS18075	COG0438	transferase activity, transferring glycosyl groups
JT25_RS18080	COG0438	transferase activity, transferring glycosyl groups
JT25_RS18085	COG0438	transferase activity, transferring glycosyl groups
JT25_RS18120	COG1216	Glycosyl transferase, family 2
JT25_RS18145	COG4536	flavin adenine dinucleotide binding
JT25_RS18155	COG1473	amidohydrolase
JT25_RS18170	COG1450	Type ii and iii secretion system protein
JT25_RS18185	COG3166	PFAM Fimbrial assembly family protein
JT25_RS18190	COG3156	type II secretion system protein K
JT25_RS18200	COG2165	general secretion pathway protein
JT25_RS18215	COG1459	type II secretion system
JT25_RS18225	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JT25_RS18240	COG3040	lipid binding
JT25_RS18245	COG0415	Belongs to the DNA photolyase family
JT25_RS18255	COG1090	epimerase
JT25_RS18260	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
JT25_RS18275	COG2202	Pas domain
JT25_RS18275	COG1366	Belongs to the anti-sigma-factor antagonist family
JT25_RS18295	COG0330	HflC and HflK could
JT25_RS18300	COG0330	HflC and HflK could
JT25_RS18305	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JT25_RS18345	COG4628	conserved protein (DUF2132)
JT25_RS18365	COG2132	Multicopper oxidase
JT25_RS18380	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JT25_RS18460	COG2204	response regulator
JT25_RS18465	COG4774	siderophore transport
JT25_RS18470	COG2223	nitrite transmembrane transporter activity
JT25_RS18495	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JT25_RS18495	COG0617	tRNA 3'-terminal CCA addition
JT25_RS18495	COG0517	IMP dehydrogenase activity
JT25_RS18510	COG1490	D-aminoacyl-tRNA deacylase activity
JT25_RS18515	COG2105	PFAM AIG2 family protein
JT25_RS18540	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JT25_RS18545	COG1205	dead DEAH box helicase
JT25_RS18545	COG1111	helicase
JT25_RS18550	COG2801	Transposase and inactivated derivatives
JT25_RS18565	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JT25_RS18580	COG2801	Transposase and inactivated derivatives
JT25_RS18605	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JT25_RS18610	COG1047	Peptidyl-prolyl cis-trans
JT25_RS18635	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JT25_RS18640	COG0583	DNA-binding transcription factor activity
JT25_RS18650	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JT25_RS18655	COG1472	Belongs to the glycosyl hydrolase 3 family
JT25_RS18665	COG2201	protein-glutamate methylesterase activity
JT25_RS18670	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
JT25_RS18695	COG2198	Histidine kinase
JT25_RS18695	COG0643	Histidine kinase
JT25_RS18705	COG0835	chemotaxis
JT25_RS18715	COG2703	oxygen carrier activity
JT25_RS18720	COG0840	transmembrane signaling receptor activity
JT25_RS18725	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JT25_RS18730	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JT25_RS18735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JT25_RS18740	COG3001	Fructosamine kinase
JT25_RS18745	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JT25_RS18800	COG1278	Cold shock
JT25_RS18805	COG1132	(ABC) transporter
JT25_RS18810	COG1295	ribonuclease BN
JT25_RS18820	COG2199	diguanylate cyclase activity
JT25_RS18820	COG2200	EAL domain
JT25_RS18820	COG3287	FIST C domain
JT25_RS18845	COG0686	Belongs to the AlaDH PNT family
JT25_RS18900	COG1131	(ABC) transporter
JT25_RS18950	COG3328	transposase activity
JT25_RS18960	COG0473	3-isopropylmalate dehydrogenase activity
JT25_RS18965	COG2095	MarC family integral membrane protein
JT25_RS18975	COG0583	DNA-binding transcription factor activity
JT25_RS18990	COG2823	Periplasmic or secreted lipoprotein
JT25_RS19025	COG0678	peroxiredoxin activity
JT25_RS19085	COG1657	PFAM Prenyltransferase squalene oxidase
JT25_RS19105	COG2885	chlorophyll binding
JT25_RS19145	COG3459	Glycosyltransferase 36 associated
JT25_RS19220	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JT25_RS19220	COG0546	phosphoglycolate phosphatase activity
JT25_RS19235	COG2885	chlorophyll binding
JT25_RS19235	COG3047	cAMP biosynthetic process
JT25_RS19240	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JT25_RS19250	COG0114	fumarate hydratase activity
JT25_RS19270	COG3293	Transposase
JT25_RS19320	COG3293	Transposase
JT25_RS19335	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
JT25_RS19340	COG0189	ligase activity
JT25_RS19350	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
JT25_RS19360	COG0189	ligase activity
JT25_RS19390	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JT25_RS19395	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JT25_RS19410	COG5001	Diguanylate cyclase
JT25_RS19410	COG2203	Gaf domain
JT25_RS19410	COG3706	GGDEF domain
JT25_RS19410	COG4251	negative regulation of phosphorylation
JT25_RS19420	COG3256	nitric oxide reductase
JT25_RS19425	COG2010	Cytochrome c
JT25_RS19435	COG1959	2 iron, 2 sulfur cluster binding
JT25_RS19440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JT25_RS19445	COG0508	dehydrogenase complex catalyzes the overall conversion of
JT25_RS19485	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JT25_RS19505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JT25_RS19510	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JT25_RS19545	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
JT25_RS19550	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
JT25_RS19555	COG3706	GGDEF domain
JT25_RS19555	COG4251	negative regulation of phosphorylation
JT25_RS19555	COG5001	Diguanylate cyclase
JT25_RS19555	COG2203	Gaf domain
JT25_RS19565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JT25_RS19595	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JT25_RS19635	COG0513	Belongs to the DEAD box helicase family
JT25_RS19645	COG4106	trans-aconitate 2-methyltransferase activity
JT25_RS19670	COG0659	secondary active sulfate transmembrane transporter activity
JT25_RS19675	COG1649	PFAM Uncharacterised BCR, COG1649
JT25_RS19675	COG0726	polysaccharide deacetylase
JT25_RS19680	COG1215	transferase activity, transferring glycosyl groups
JT25_RS19695	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JT25_RS19705	COG5016	pyruvate
JT25_RS19705	COG0511	ligase activity, forming carbon-carbon bonds
JT25_RS19710	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
JT25_RS19750	COG0438	transferase activity, transferring glycosyl groups
JT25_RS19790	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JT25_RS19805	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JT25_RS19900	COG0556	nucleotide-excision repair
JT25_RS19910	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JT25_RS19925	COG1704	LemA family
JT25_RS19940	COG0071	Belongs to the small heat shock protein (HSP20) family
JT25_RS19945	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JT25_RS19950	COG0070	glutamate synthase
JT25_RS19950	COG0069	glutamate synthase activity
JT25_RS19950	COG0067	glutamate synthase
JT25_RS19955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JT25_RS19960	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
JT25_RS19965	COG0024	Methionine aminopeptidase
JT25_RS19970	COG0052	Belongs to the universal ribosomal protein uS2 family
JT25_RS19975	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JT25_RS19980	COG0528	UMP kinase activity
JT25_RS19985	COG0233	cytoplasmic translational termination
JT25_RS19990	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JT25_RS19995	COG0575	Belongs to the CDS family
JT25_RS20000	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JT25_RS20010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JT25_RS20025	COG5002	protein histidine kinase activity
JT25_RS20025	COG2205	protein histidine kinase activity
JT25_RS20025	COG0784	Response regulator, receiver
JT25_RS20030	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JT25_RS20040	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JT25_RS20055	COG2801	Transposase and inactivated derivatives
JT25_RS20060	COG2801	Transposase and inactivated derivatives
JT25_RS20070	COG4106	trans-aconitate 2-methyltransferase activity
JT25_RS20075	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JT25_RS20090	COG3070	regulator of competence-specific genes
JT25_RS20105	COG1917	Cupin 2, conserved barrel domain protein
JT25_RS20105	COG2169	Transcriptional regulator
JT25_RS20120	COG0697	spore germination
JT25_RS20125	COG2197	response regulator
JT25_RS20190	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JT25_RS20205	COG0504	CTP synthase activity
JT25_RS20225	COG0456	acetyltransferase
JT25_RS20255	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
JT25_RS20265	COG2329	Antibiotic biosynthesis monooxygenase
JT25_RS20350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JT25_RS20365	COG2801	Transposase and inactivated derivatives
JT25_RS20375	COG2801	Transposase and inactivated derivatives
JT25_RS20410	COG4555	ABC transporter
JT25_RS20415	COG0473	3-isopropylmalate dehydrogenase activity
JT25_RS20425	COG1049	propionate catabolic process, 2-methylcitrate cycle
JT25_RS20435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JT25_RS20440	COG0037	tRNA processing
JT25_RS20450	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JT25_RS20455	COG0741	lytic transglycosylase activity
JT25_RS20460	COG1132	(ABC) transporter
JT25_RS20465	COG0613	PHP domain protein
JT25_RS20470	COG5001	Diguanylate cyclase
JT25_RS20470	COG3300	MHYT domain
JT25_RS20480	COG0784	Response regulator, receiver
JT25_RS20480	COG5002	protein histidine kinase activity
JT25_RS20480	COG2205	protein histidine kinase activity
JT25_RS20490	COG4771	TonB-dependent receptor
JT25_RS20565	COG2165	general secretion pathway protein
JT25_RS20570	COG2165	general secretion pathway protein
JT25_RS20585	COG1459	type II secretion system
JT25_RS20590	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JT25_RS20600	COG3267	Type II secretory pathway component ExeA
JT25_RS20600	COG3409	Peptidoglycan-binding domain 1 protein
JT25_RS20655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JT25_RS20655	COG3153	acetyltransferase
JT25_RS20670	COG2914	Belongs to the UPF0125 (RnfH) family
JT25_RS20675	COG2867	negative regulation of translational initiation
JT25_RS20680	COG0733	neurotransmitter:sodium symporter activity
JT25_RS20685	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JT25_RS20695	COG1477	protein flavinylation
JT25_RS20705	COG0135	phosphoribosylanthranilate isomerase activity
JT25_RS20710	COG0133	tryptophan synthase activity
JT25_RS20715	COG0159	tryptophan synthase activity
JT25_RS20720	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JT25_RS20725	COG0285	dihydrofolate synthase activity
JT25_RS20735	COG1286	toxin biosynthetic process
JT25_RS20765	COG3264	Mechanosensitive ion channel
JT25_RS20765	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
JT25_RS20770	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JT25_RS20775	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JT25_RS20775	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JT25_RS20795	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JT25_RS20800	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JT25_RS20810	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JT25_RS20825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JT25_RS20870	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JT25_RS20875	COG3657	addiction module killer protein
JT25_RS20880	COG0582	viral genome integration into host DNA
JT25_RS20890	COG2801	Transposase and inactivated derivatives
JT25_RS20945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JT25_RS20965	COG4993	Dehydrogenase
JT25_RS20970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JT25_RS20975	COG2010	Cytochrome c
JT25_RS20985	COG0714	Associated with various cellular activities
JT25_RS21035	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JT25_RS21040	COG0243	molybdopterin cofactor binding
JT25_RS21045	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JT25_RS21055	COG1116	anion transmembrane transporter activity
JT25_RS21055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JT25_RS21060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JT25_RS21065	COG1116	anion transmembrane transporter activity
JT25_RS21065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JT25_RS21075	COG0583	DNA-binding transcription factor activity
JT25_RS21105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JT25_RS21120	COG0456	acetyltransferase
JT25_RS21125	COG0436	Aminotransferase
JT25_RS21135	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JT25_RS21145	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JT25_RS21160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JT25_RS21175	COG3851	Histidine kinase
JT25_RS21185	COG1639	'signal transduction protein
JT25_RS21210	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JT25_RS21220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JT25_RS21225	COG0287	Prephenate dehydrogenase
JT25_RS21230	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JT25_RS21235	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JT25_RS21255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JT25_RS21260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JT25_RS21265	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JT25_RS21280	COG4133	protoheme IX ABC transporter activity
JT25_RS21300	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
JT25_RS21305	COG1138	Cytochrome C-type biogenesis protein
JT25_RS21310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JT25_RS21335	COG3328	transposase activity
JT25_RS21345	COG1966	Carbon starvation protein
JT25_RS21355	COG0123	including yeast histone deacetylase and acetoin utilization protein
JT25_RS21360	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JT25_RS21365	COG3038	cytochrome b561
JT25_RS21370	COG4191	Histidine kinase
JT25_RS21370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JT25_RS21375	COG0784	Response regulator, receiver
JT25_RS21375	COG3437	response regulator, receiver
JT25_RS21390	COG2833	Protein of unknown function (DUF455)
JT25_RS21400	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JT25_RS21425	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JT25_RS21430	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JT25_RS21435	COG2871	sodium ion transport
JT25_RS21455	COG1570	exodeoxyribonuclease VII activity
JT25_RS21485	COG2814	Major facilitator Superfamily
JT25_RS21505	COG3293	Transposase
JT25_RS21545	COG0165	Argininosuccinate lyase
JT25_RS21575	COG0840	transmembrane signaling receptor activity
JT25_RS21590	COG3072	Adenylate cyclase
JT25_RS21600	COG4771	TonB-dependent receptor
JT25_RS21650	COG0354	folic acid binding
JT25_RS21670	COG0012	GTP binding
JT25_RS21700	COG0732	type I restriction modification DNA specificity domain
JT25_RS21755	COG0475	glutathione-regulated potassium exporter activity
JT25_RS21775	COG3293	Transposase
JT25_RS21790	COG0114	fumarate hydratase activity
JT25_RS21815	COG5001	Diguanylate cyclase
JT25_RS21815	COG5002	protein histidine kinase activity
JT25_RS21815	COG3447	MASE1 domain protein
JT25_RS21825	COG2963	transposase activity
JT25_RS21840	COG4191	Histidine kinase
JT25_RS21845	COG4566	intracellular signal transduction
JT25_RS21875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JT25_RS21885	COG1028	Short-chain dehydrogenase reductase Sdr
JT25_RS21890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JT25_RS21900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JT25_RS21945	COG1960	acyl-CoA dehydrogenase activity
JT25_RS21960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JT25_RS21970	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JT25_RS21995	COG0714	Associated with various cellular activities
JT25_RS22015	COG0582	viral genome integration into host DNA
JT25_RS22020	COG0583	DNA-binding transcription factor activity
JT25_RS22030	COG1902	pentaerythritol trinitrate reductase activity
JT25_RS22040	COG1335	isochorismatase
JT25_RS22050	COG1131	(ABC) transporter
JT25_RS22055	COG0842	Transport permease protein
JT25_RS22060	COG0842	Transport permease protein
JT25_RS22065	COG1538	Outer membrane efflux protein
JT25_RS22130	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
JT25_RS22165	COG2925	Exonuclease
JT25_RS22170	COG0436	Aminotransferase
JT25_RS22185	COG0101	tRNA pseudouridine synthase activity
JT25_RS22195	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JT25_RS22215	COG5001	Diguanylate cyclase
JT25_RS22215	COG5002	protein histidine kinase activity
JT25_RS22235	COG2801	Transposase and inactivated derivatives
JT25_RS22245	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
JT25_RS22250	COG2835	tetraacyldisaccharide 4'-kinase activity
JT25_RS22255	COG1663	tetraacyldisaccharide 4'-kinase activity
JT25_RS22265	COG0811	peptide transport
JT25_RS22275	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JT25_RS22280	COG2890	protein-(glutamine-N5) methyltransferase activity
JT25_RS22300	COG4452	Inner membrane protein CreD
JT25_RS22305	COG2226	methyltransferase
JT25_RS22310	COG0384	phenazine biosynthesis protein PhzF
JT25_RS22315	COG2146	nitrite reductase [NAD(P)H] activity
JT25_RS22320	COG2146	nitrite reductase [NAD(P)H] activity
JT25_RS22320	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JT25_RS22325	COG2223	nitrite transmembrane transporter activity
JT25_RS22330	COG3707	response regulator
JT25_RS22350	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
JT25_RS22355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JT25_RS22360	COG0842	Transport permease protein
JT25_RS22365	COG1131	(ABC) transporter
JT25_RS22370	COG0248	Ppx GppA phosphatase
JT25_RS22385	COG0484	heat shock protein binding
JT25_RS22390	COG1763	Mo-molybdopterin cofactor biosynthetic process
JT25_RS22405	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JT25_RS22410	COG0436	Aminotransferase
JT25_RS22420	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JT25_RS22425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JT25_RS22430	COG0697	spore germination
JT25_RS22445	COG1538	Outer membrane efflux protein
JT25_RS22450	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JT25_RS22455	COG1074	ATP-dependent DNA helicase activity
JT25_RS22460	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JT25_RS22470	COG0500	methyltransferase
JT25_RS22520	COG4771	TonB-dependent receptor
JT25_RS22540	COG3829	transcription factor binding
JT25_RS22545	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JT25_RS22580	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JT25_RS22585	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JT25_RS22585	COG2010	Cytochrome c
JT25_RS22600	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
JT25_RS22620	COG0702	epimerase
JT25_RS22645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JT25_RS22650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JT25_RS22705	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JT25_RS22720	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
JT25_RS22725	COG4208	sulfate ABC transporter
JT25_RS22730	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JT25_RS22735	COG0583	DNA-binding transcription factor activity
JT25_RS22740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JT25_RS22745	COG1045	serine acetyltransferase
JT25_RS22750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JT25_RS22755	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JT25_RS22895	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JT25_RS22900	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JT25_RS22910	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JT25_RS22955	COG1538	Outer membrane efflux protein
JT25_RS22960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JT25_RS22965	COG1129	ABC transporter
JT25_RS22965	COG0842	Transport permease protein
JT25_RS22970	COG0842	Transport permease protein
JT25_RS23030	COG1742	UPF0060 membrane protein
JT25_RS23100	COG0681	Belongs to the peptidase S26 family
JT25_RS23155	COG4772	TonB-dependent receptor
JT25_RS23160	COG1181	Belongs to the D-alanine--D-alanine ligase family
JT25_RS23180	COG0019	diaminopimelate decarboxylase activity
JT25_RS23185	COG3836	Belongs to the HpcH HpaI aldolase family
JT25_RS23205	COG4804	nuclease activity
JT25_RS23225	COG0629	single-stranded DNA binding
JT25_RS23330	COG0582	viral genome integration into host DNA
JT25_RS23350	COG0072	phenylalanine-tRNA ligase activity
JT25_RS23350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JT25_RS23355	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JT25_RS23360	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JT25_RS23365	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JT25_RS23370	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JT25_RS23375	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JT25_RS23390	COG0408	coproporphyrinogen oxidase activity
JT25_RS23395	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
JT25_RS23420	COG1404	Belongs to the peptidase S8 family
JT25_RS23440	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JT25_RS23445	COG1132	(ABC) transporter
JT25_RS23475	COG0438	transferase activity, transferring glycosyl groups
JT25_RS23490	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JT25_RS23505	COG1643	Atp-dependent helicase
JT25_RS23525	COG3293	Transposase
JT25_RS23545	COG0583	DNA-binding transcription factor activity
JT25_RS23560	COG3293	Transposase