MKLM6_RS18560 44d5d7849ea7bbabc18f99fe3645a729 188 SUPERFAMILY SSF89392 17 186 2.35E-33 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX MKLM6_RS18560 44d5d7849ea7bbabc18f99fe3645a729 188 TIGRFAM TIGR00548 lolB: outer membrane lipoprotein LolB 12 185 3.4E-21 T 28-03-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 MKLM6_RS18560 44d5d7849ea7bbabc18f99fe3645a729 188 Pfam PF03550 Outer membrane lipoprotein LolB 40 185 2.2E-31 T 28-03-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 MKLM6_RS18560 44d5d7849ea7bbabc18f99fe3645a729 188 Gene3D G3DSA:2.50.20.10 32 188 9.3E-32 T 28-03-2018 MKLM6_RS07145 8f4446c84a7783165ae6b58a98271a0f 94 Gene3D G3DSA:3.40.1690.10 9 86 1.0E-27 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal MKLM6_RS07145 8f4446c84a7783165ae6b58a98271a0f 94 SUPERFAMILY SSF160544 10 85 4.45E-23 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal MKLM6_RS07145 8f4446c84a7783165ae6b58a98271a0f 94 Pfam PF01312 FlhB HrpN YscU SpaS Family 10 81 1.4E-21 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MKLM6_RS10735 addfc4fe9fe230fbe47123a79a4a94de 244 Pfam PF06804 NlpB/DapX lipoprotein 85 223 1.0E-11 T 28-03-2018 IPR010653 NlpB/DapX lipoprotein MKLM6_RS11965 2b89596c1b5cee12f94fbcbea0a5104f 617 Gene3D G3DSA:3.40.50.2300 490 616 2.5E-14 T 28-03-2018 MKLM6_RS11965 2b89596c1b5cee12f94fbcbea0a5104f 617 SUPERFAMILY SSF52172 492 609 4.98E-15 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS11965 2b89596c1b5cee12f94fbcbea0a5104f 617 Gene3D G3DSA:3.30.565.10 317 477 2.3E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS11965 2b89596c1b5cee12f94fbcbea0a5104f 617 SUPERFAMILY SSF55874 300 470 2.75E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS11965 2b89596c1b5cee12f94fbcbea0a5104f 617 SUPERFAMILY SSF47384 232 311 2.55E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS11965 2b89596c1b5cee12f94fbcbea0a5104f 617 Pfam PF00512 His Kinase A (phospho-acceptor) domain 244 311 2.7E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS11965 2b89596c1b5cee12f94fbcbea0a5104f 617 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 359 468 1.7E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS11965 2b89596c1b5cee12f94fbcbea0a5104f 617 SMART SM00448 490 603 4.4E-5 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS11965 2b89596c1b5cee12f94fbcbea0a5104f 617 Gene3D G3DSA:1.10.287.130 234 306 2.8E-6 T 28-03-2018 MKLM6_RS11965 2b89596c1b5cee12f94fbcbea0a5104f 617 SMART SM00388 243 311 5.7E-4 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS11965 2b89596c1b5cee12f94fbcbea0a5104f 617 Pfam PF00072 Response regulator receiver domain 492 577 1.8E-6 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS11965 2b89596c1b5cee12f94fbcbea0a5104f 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 469 9.3E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS11965 2b89596c1b5cee12f94fbcbea0a5104f 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 423 9.3E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS11965 2b89596c1b5cee12f94fbcbea0a5104f 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 449 9.3E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS11965 2b89596c1b5cee12f94fbcbea0a5104f 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 409 9.3E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS11965 2b89596c1b5cee12f94fbcbea0a5104f 617 SMART SM00387 358 472 8.9E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS04555 441d03e6abb8f56424016b28ee2bf468 203 Gene3D G3DSA:3.40.50.150 4 194 4.3E-16 T 28-03-2018 MKLM6_RS04555 441d03e6abb8f56424016b28ee2bf468 203 Pfam PF13489 Methyltransferase domain 36 143 9.5E-11 T 28-03-2018 MKLM6_RS04555 441d03e6abb8f56424016b28ee2bf468 203 SUPERFAMILY SSF53335 7 188 9.09E-19 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 PRINTS PR00943 Copper-transporting ATPase signature 182 201 8.7E-12 T 28-03-2018 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 PRINTS PR00943 Copper-transporting ATPase signature 130 149 8.7E-12 T 28-03-2018 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 PRINTS PR00943 Copper-transporting ATPase signature 590 607 8.7E-12 T 28-03-2018 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 PRINTS PR00943 Copper-transporting ATPase signature 335 349 8.7E-12 T 28-03-2018 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 PRINTS PR00943 Copper-transporting ATPase signature 202 220 8.7E-12 T 28-03-2018 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 Gene3D G3DSA:3.30.70.100 1 48 7.2E-18 T 28-03-2018 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 SUPERFAMILY SSF81665 662 676 4.18E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 SUPERFAMILY SSF81665 180 216 4.18E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 SUPERFAMILY SSF81665 313 408 4.18E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 Pfam PF00403 Heavy-metal-associated domain 1 53 2.4E-13 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 414 428 6.6E-32 T 28-03-2018 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 560 570 6.6E-32 T 28-03-2018 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 636 648 6.6E-32 T 28-03-2018 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 262 276 6.6E-32 T 28-03-2018 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 538 549 6.6E-32 T 28-03-2018 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 613 632 6.6E-32 T 28-03-2018 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 SUPERFAMILY SSF55008 1 56 1.18E-15 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 SUPERFAMILY SSF56784 471 719 2.95E-56 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 SUPERFAMILY SSF56784 413 432 2.95E-56 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 416 422 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 Gene3D G3DSA:1.20.1110.10 49 430 7.2E-41 T 28-03-2018 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 Pfam PF00702 haloacid dehalogenase-like hydrolase 412 627 1.4E-43 T 28-03-2018 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 127 723 3.1E-179 T 28-03-2018 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 184 691 4.5E-89 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 Gene3D G3DSA:3.40.50.1000 540 678 9.0E-44 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 Pfam PF00122 E1-E2 ATPase 213 392 7.9E-56 T 28-03-2018 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 145 722 6.0E-187 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 Gene3D G3DSA:3.40.1110.10 431 539 1.8E-31 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MKLM6_RS16535 a2942f7c5183eda115006ca05be9a421 731 SUPERFAMILY SSF81653 214 312 2.22E-27 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MKLM6_RS00035 81911cf9d063a488160bd753a6687cc8 921 Pfam PF12698 ABC-2 family transporter protein 576 912 4.0E-40 T 28-03-2018 MKLM6_RS00035 81911cf9d063a488160bd753a6687cc8 921 Pfam PF00005 ABC transporter 288 432 5.8E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS00035 81911cf9d063a488160bd753a6687cc8 921 Pfam PF00005 ABC transporter 23 170 3.0E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS00035 81911cf9d063a488160bd753a6687cc8 921 SUPERFAMILY SSF52540 263 497 6.39E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS00035 81911cf9d063a488160bd753a6687cc8 921 Gene3D G3DSA:3.40.50.300 4 266 1.4E-62 T 28-03-2018 MKLM6_RS00035 81911cf9d063a488160bd753a6687cc8 921 Gene3D G3DSA:3.40.50.300 270 534 9.4E-62 T 28-03-2018 MKLM6_RS00035 81911cf9d063a488160bd753a6687cc8 921 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS00035 81911cf9d063a488160bd753a6687cc8 921 Gene3D G3DSA:3.40.1710.10 587 739 2.3E-21 T 28-03-2018 MKLM6_RS00035 81911cf9d063a488160bd753a6687cc8 921 SMART SM00382 32 249 4.4E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS00035 81911cf9d063a488160bd753a6687cc8 921 SMART SM00382 297 488 8.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS00035 81911cf9d063a488160bd753a6687cc8 921 SUPERFAMILY SSF52540 6 233 8.1E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS07235 d986fa8ae1a4a879d785620f0ed7a229 328 PIRSF PIRSF004911 2 328 3.1E-112 T 28-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase MKLM6_RS07235 d986fa8ae1a4a879d785620f0ed7a229 328 SUPERFAMILY SSF102114 95 315 9.03E-25 T 28-03-2018 MKLM6_RS07235 d986fa8ae1a4a879d785620f0ed7a229 328 Pfam PF13394 4Fe-4S single cluster domain 107 189 4.4E-8 T 28-03-2018 MKLM6_RS07235 d986fa8ae1a4a879d785620f0ed7a229 328 Pfam PF04055 Radical SAM superfamily 108 230 4.9E-10 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS07235 d986fa8ae1a4a879d785620f0ed7a229 328 TIGRFAM TIGR03821 EFP_modif_epmB: EF-P beta-lysylation protein EpmB 8 327 3.5E-128 T 28-03-2018 IPR022462 Lysine-2,3-aminomutase-like MKLM6_RS07235 d986fa8ae1a4a879d785620f0ed7a229 328 Gene3D G3DSA:3.20.20.70 93 309 5.4E-17 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS07235 d986fa8ae1a4a879d785620f0ed7a229 328 TIGRFAM TIGR00238 TIGR00238: KamA family protein 7 320 2.0E-96 T 28-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase MKLM6_RS08320 450040f201fd04b07c9366d048c5d882 104 SUPERFAMILY SSF46689 8 102 1.97E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS08320 450040f201fd04b07c9366d048c5d882 104 Pfam PF01527 Transposase 8 87 2.8E-9 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MKLM6_RS08320 450040f201fd04b07c9366d048c5d882 104 Gene3D G3DSA:1.10.10.60 13 98 7.7E-22 T 28-03-2018 MKLM6_RS07930 450040f201fd04b07c9366d048c5d882 104 SUPERFAMILY SSF46689 8 102 1.97E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS07930 450040f201fd04b07c9366d048c5d882 104 Pfam PF01527 Transposase 8 87 2.8E-9 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MKLM6_RS07930 450040f201fd04b07c9366d048c5d882 104 Gene3D G3DSA:1.10.10.60 13 98 7.7E-22 T 28-03-2018 MKLM6_RS08200 450040f201fd04b07c9366d048c5d882 104 SUPERFAMILY SSF46689 8 102 1.97E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS08200 450040f201fd04b07c9366d048c5d882 104 Pfam PF01527 Transposase 8 87 2.8E-9 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MKLM6_RS08200 450040f201fd04b07c9366d048c5d882 104 Gene3D G3DSA:1.10.10.60 13 98 7.7E-22 T 28-03-2018 MKLM6_RS13490 450040f201fd04b07c9366d048c5d882 104 SUPERFAMILY SSF46689 8 102 1.97E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS13490 450040f201fd04b07c9366d048c5d882 104 Pfam PF01527 Transposase 8 87 2.8E-9 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MKLM6_RS13490 450040f201fd04b07c9366d048c5d882 104 Gene3D G3DSA:1.10.10.60 13 98 7.7E-22 T 28-03-2018 MKLM6_RS06600 450040f201fd04b07c9366d048c5d882 104 SUPERFAMILY SSF46689 8 102 1.97E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS06600 450040f201fd04b07c9366d048c5d882 104 Pfam PF01527 Transposase 8 87 2.8E-9 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MKLM6_RS06600 450040f201fd04b07c9366d048c5d882 104 Gene3D G3DSA:1.10.10.60 13 98 7.7E-22 T 28-03-2018 MKLM6_RS08355 450040f201fd04b07c9366d048c5d882 104 SUPERFAMILY SSF46689 8 102 1.97E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS08355 450040f201fd04b07c9366d048c5d882 104 Pfam PF01527 Transposase 8 87 2.8E-9 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MKLM6_RS08355 450040f201fd04b07c9366d048c5d882 104 Gene3D G3DSA:1.10.10.60 13 98 7.7E-22 T 28-03-2018 MKLM6_RS09910 450040f201fd04b07c9366d048c5d882 104 SUPERFAMILY SSF46689 8 102 1.97E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS09910 450040f201fd04b07c9366d048c5d882 104 Pfam PF01527 Transposase 8 87 2.8E-9 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MKLM6_RS09910 450040f201fd04b07c9366d048c5d882 104 Gene3D G3DSA:1.10.10.60 13 98 7.7E-22 T 28-03-2018 MKLM6_RS04220 450040f201fd04b07c9366d048c5d882 104 SUPERFAMILY SSF46689 8 102 1.97E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS04220 450040f201fd04b07c9366d048c5d882 104 Pfam PF01527 Transposase 8 87 2.8E-9 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MKLM6_RS04220 450040f201fd04b07c9366d048c5d882 104 Gene3D G3DSA:1.10.10.60 13 98 7.7E-22 T 28-03-2018 MKLM6_RS08340 450040f201fd04b07c9366d048c5d882 104 SUPERFAMILY SSF46689 8 102 1.97E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS08340 450040f201fd04b07c9366d048c5d882 104 Pfam PF01527 Transposase 8 87 2.8E-9 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MKLM6_RS08340 450040f201fd04b07c9366d048c5d882 104 Gene3D G3DSA:1.10.10.60 13 98 7.7E-22 T 28-03-2018 MKLM6_RS13160 450040f201fd04b07c9366d048c5d882 104 SUPERFAMILY SSF46689 8 102 1.97E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS13160 450040f201fd04b07c9366d048c5d882 104 Pfam PF01527 Transposase 8 87 2.8E-9 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MKLM6_RS13160 450040f201fd04b07c9366d048c5d882 104 Gene3D G3DSA:1.10.10.60 13 98 7.7E-22 T 28-03-2018 MKLM6_RS22720 450040f201fd04b07c9366d048c5d882 104 SUPERFAMILY SSF46689 8 102 1.97E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS22720 450040f201fd04b07c9366d048c5d882 104 Pfam PF01527 Transposase 8 87 2.8E-9 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MKLM6_RS22720 450040f201fd04b07c9366d048c5d882 104 Gene3D G3DSA:1.10.10.60 13 98 7.7E-22 T 28-03-2018 MKLM6_RS14020 450040f201fd04b07c9366d048c5d882 104 SUPERFAMILY SSF46689 8 102 1.97E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS14020 450040f201fd04b07c9366d048c5d882 104 Pfam PF01527 Transposase 8 87 2.8E-9 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MKLM6_RS14020 450040f201fd04b07c9366d048c5d882 104 Gene3D G3DSA:1.10.10.60 13 98 7.7E-22 T 28-03-2018 MKLM6_RS04345 450040f201fd04b07c9366d048c5d882 104 SUPERFAMILY SSF46689 8 102 1.97E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS04345 450040f201fd04b07c9366d048c5d882 104 Pfam PF01527 Transposase 8 87 2.8E-9 T 28-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MKLM6_RS04345 450040f201fd04b07c9366d048c5d882 104 Gene3D G3DSA:1.10.10.60 13 98 7.7E-22 T 28-03-2018 MKLM6_RS12025 237e076516b26b2ef2fad6f817d91aec 199 SUPERFAMILY SSF53254 5 186 1.37E-43 T 28-03-2018 IPR029033 Histidine phosphatase superfamily MKLM6_RS12025 237e076516b26b2ef2fad6f817d91aec 199 SMART SM00855 6 155 8.6E-10 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MKLM6_RS12025 237e076516b26b2ef2fad6f817d91aec 199 PIRSF PIRSF000709 5 183 3.3E-5 T 28-03-2018 MKLM6_RS12025 237e076516b26b2ef2fad6f817d91aec 199 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 9 183 5.0E-39 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MKLM6_RS12025 237e076516b26b2ef2fad6f817d91aec 199 Gene3D G3DSA:3.40.50.1240 3 197 6.1E-44 T 28-03-2018 IPR029033 Histidine phosphatase superfamily MKLM6_RS10400 60cef5974ff1e0859ad6215ced1268d9 208 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 142 203 5.9E-7 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 MKLM6_RS10400 60cef5974ff1e0859ad6215ced1268d9 208 Pfam PF13103 TonB C terminal 121 202 1.4E-6 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 MKLM6_RS10400 60cef5974ff1e0859ad6215ced1268d9 208 Gene3D G3DSA:3.30.1150.10 41 208 1.3E-7 T 28-03-2018 MKLM6_RS10400 60cef5974ff1e0859ad6215ced1268d9 208 SUPERFAMILY SSF74653 110 202 1.44E-13 T 28-03-2018 MKLM6_RS10400 60cef5974ff1e0859ad6215ced1268d9 208 SUPERFAMILY SSF74653 69 82 1.44E-13 T 28-03-2018 MKLM6_RS09950 6f5e56dc33ab0eb8bc6d0ebcb66e8578 319 Pfam PF01544 CorA-like Mg2+ transporter protein 28 315 5.7E-57 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 MKLM6_RS09950 6f5e56dc33ab0eb8bc6d0ebcb66e8578 319 Gene3D G3DSA:1.20.58.340 135 251 6.5E-26 T 28-03-2018 MKLM6_RS09950 6f5e56dc33ab0eb8bc6d0ebcb66e8578 319 Gene3D G3DSA:3.30.460.20 1 131 4.1E-31 T 28-03-2018 MKLM6_RS09950 6f5e56dc33ab0eb8bc6d0ebcb66e8578 319 Gene3D G3DSA:1.20.58.340 252 319 1.7E-15 T 28-03-2018 MKLM6_RS09950 6f5e56dc33ab0eb8bc6d0ebcb66e8578 319 SUPERFAMILY SSF143865 3 249 1.18E-62 T 28-03-2018 MKLM6_RS09950 6f5e56dc33ab0eb8bc6d0ebcb66e8578 319 SUPERFAMILY SSF144083 254 316 8.63E-17 T 28-03-2018 MKLM6_RS20630 d63d8f6e8ede1a87647db35a1ba4997a 303 SMART SM00240 52 102 2.7E-13 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MKLM6_RS20630 d63d8f6e8ede1a87647db35a1ba4997a 303 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 139 301 7.2E-49 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS20630 d63d8f6e8ede1a87647db35a1ba4997a 303 SUPERFAMILY SSF55073 145 301 1.96E-46 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS20630 d63d8f6e8ede1a87647db35a1ba4997a 303 Pfam PF00990 Diguanylate cyclase, GGDEF domain 140 298 1.4E-45 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS20630 d63d8f6e8ede1a87647db35a1ba4997a 303 Gene3D G3DSA:2.60.200.20 12 124 1.8E-24 T 28-03-2018 MKLM6_RS20630 d63d8f6e8ede1a87647db35a1ba4997a 303 SMART SM00267 129 302 3.1E-55 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS20630 d63d8f6e8ede1a87647db35a1ba4997a 303 Gene3D G3DSA:3.30.70.270 128 303 3.6E-53 T 28-03-2018 MKLM6_RS20630 d63d8f6e8ede1a87647db35a1ba4997a 303 SUPERFAMILY SSF49879 31 131 7.27E-28 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MKLM6_RS20630 d63d8f6e8ede1a87647db35a1ba4997a 303 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 36 122 5.6E-21 T 28-03-2018 IPR032030 YscD, cytoplasmic domain MKLM6_RS06595 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF13276 HTH-like domain 23 79 3.1E-12 T 28-03-2018 IPR025948 HTH-like domain MKLM6_RS06595 cdfaefad553a5219fc2757f868cdb441 268 Gene3D G3DSA:3.30.420.10 99 268 1.8E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS06595 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF00665 Integrase core domain 104 218 4.8E-33 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MKLM6_RS06595 cdfaefad553a5219fc2757f868cdb441 268 SUPERFAMILY SSF53098 97 260 4.55E-43 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS08335 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF13276 HTH-like domain 23 79 3.1E-12 T 28-03-2018 IPR025948 HTH-like domain MKLM6_RS08335 cdfaefad553a5219fc2757f868cdb441 268 Gene3D G3DSA:3.30.420.10 99 268 1.8E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS08335 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF00665 Integrase core domain 104 218 4.8E-33 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MKLM6_RS08335 cdfaefad553a5219fc2757f868cdb441 268 SUPERFAMILY SSF53098 97 260 4.55E-43 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS07935 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF13276 HTH-like domain 23 79 3.1E-12 T 28-03-2018 IPR025948 HTH-like domain MKLM6_RS07935 cdfaefad553a5219fc2757f868cdb441 268 Gene3D G3DSA:3.30.420.10 99 268 1.8E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS07935 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF00665 Integrase core domain 104 218 4.8E-33 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MKLM6_RS07935 cdfaefad553a5219fc2757f868cdb441 268 SUPERFAMILY SSF53098 97 260 4.55E-43 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS08205 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF13276 HTH-like domain 23 79 3.1E-12 T 28-03-2018 IPR025948 HTH-like domain MKLM6_RS08205 cdfaefad553a5219fc2757f868cdb441 268 Gene3D G3DSA:3.30.420.10 99 268 1.8E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS08205 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF00665 Integrase core domain 104 218 4.8E-33 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MKLM6_RS08205 cdfaefad553a5219fc2757f868cdb441 268 SUPERFAMILY SSF53098 97 260 4.55E-43 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS13155 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF13276 HTH-like domain 23 79 3.1E-12 T 28-03-2018 IPR025948 HTH-like domain MKLM6_RS13155 cdfaefad553a5219fc2757f868cdb441 268 Gene3D G3DSA:3.30.420.10 99 268 1.8E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS13155 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF00665 Integrase core domain 104 218 4.8E-33 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MKLM6_RS13155 cdfaefad553a5219fc2757f868cdb441 268 SUPERFAMILY SSF53098 97 260 4.55E-43 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS13495 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF13276 HTH-like domain 23 79 3.1E-12 T 28-03-2018 IPR025948 HTH-like domain MKLM6_RS13495 cdfaefad553a5219fc2757f868cdb441 268 Gene3D G3DSA:3.30.420.10 99 268 1.8E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS13495 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF00665 Integrase core domain 104 218 4.8E-33 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MKLM6_RS13495 cdfaefad553a5219fc2757f868cdb441 268 SUPERFAMILY SSF53098 97 260 4.55E-43 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS22715 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF13276 HTH-like domain 23 79 3.1E-12 T 28-03-2018 IPR025948 HTH-like domain MKLM6_RS22715 cdfaefad553a5219fc2757f868cdb441 268 Gene3D G3DSA:3.30.420.10 99 268 1.8E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS22715 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF00665 Integrase core domain 104 218 4.8E-33 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MKLM6_RS22715 cdfaefad553a5219fc2757f868cdb441 268 SUPERFAMILY SSF53098 97 260 4.55E-43 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS04225 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF13276 HTH-like domain 23 79 3.1E-12 T 28-03-2018 IPR025948 HTH-like domain MKLM6_RS04225 cdfaefad553a5219fc2757f868cdb441 268 Gene3D G3DSA:3.30.420.10 99 268 1.8E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS04225 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF00665 Integrase core domain 104 218 4.8E-33 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MKLM6_RS04225 cdfaefad553a5219fc2757f868cdb441 268 SUPERFAMILY SSF53098 97 260 4.55E-43 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS08360 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF13276 HTH-like domain 23 79 3.1E-12 T 28-03-2018 IPR025948 HTH-like domain MKLM6_RS08360 cdfaefad553a5219fc2757f868cdb441 268 Gene3D G3DSA:3.30.420.10 99 268 1.8E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS08360 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF00665 Integrase core domain 104 218 4.8E-33 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MKLM6_RS08360 cdfaefad553a5219fc2757f868cdb441 268 SUPERFAMILY SSF53098 97 260 4.55E-43 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS04340 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF13276 HTH-like domain 23 79 3.1E-12 T 28-03-2018 IPR025948 HTH-like domain MKLM6_RS04340 cdfaefad553a5219fc2757f868cdb441 268 Gene3D G3DSA:3.30.420.10 99 268 1.8E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS04340 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF00665 Integrase core domain 104 218 4.8E-33 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MKLM6_RS04340 cdfaefad553a5219fc2757f868cdb441 268 SUPERFAMILY SSF53098 97 260 4.55E-43 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS14025 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF13276 HTH-like domain 23 79 3.1E-12 T 28-03-2018 IPR025948 HTH-like domain MKLM6_RS14025 cdfaefad553a5219fc2757f868cdb441 268 Gene3D G3DSA:3.30.420.10 99 268 1.8E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS14025 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF00665 Integrase core domain 104 218 4.8E-33 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MKLM6_RS14025 cdfaefad553a5219fc2757f868cdb441 268 SUPERFAMILY SSF53098 97 260 4.55E-43 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS08315 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF13276 HTH-like domain 23 79 3.1E-12 T 28-03-2018 IPR025948 HTH-like domain MKLM6_RS08315 cdfaefad553a5219fc2757f868cdb441 268 Gene3D G3DSA:3.30.420.10 99 268 1.8E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS08315 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF00665 Integrase core domain 104 218 4.8E-33 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MKLM6_RS08315 cdfaefad553a5219fc2757f868cdb441 268 SUPERFAMILY SSF53098 97 260 4.55E-43 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS09915 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF13276 HTH-like domain 23 79 3.1E-12 T 28-03-2018 IPR025948 HTH-like domain MKLM6_RS09915 cdfaefad553a5219fc2757f868cdb441 268 Gene3D G3DSA:3.30.420.10 99 268 1.8E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS09915 cdfaefad553a5219fc2757f868cdb441 268 Pfam PF00665 Integrase core domain 104 218 4.8E-33 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MKLM6_RS09915 cdfaefad553a5219fc2757f868cdb441 268 SUPERFAMILY SSF53098 97 260 4.55E-43 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS03400 31b0d3d413fe73264876810c6159ec50 750 Pfam PF00593 TonB dependent receptor 188 748 6.5E-48 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS03400 31b0d3d413fe73264876810c6159ec50 750 SUPERFAMILY SSF56935 2 748 6.23E-99 T 28-03-2018 MKLM6_RS03400 31b0d3d413fe73264876810c6159ec50 750 TIGRFAM TIGR01785 TonB-hemin: TonB-dependent heme/hemoglobin receptor family protein 7 750 6.4E-95 T 28-03-2018 IPR011276 TonB-dependent haem/haemoglobin receptor GO:0004872|GO:0005215|GO:0006810|GO:0019867 MKLM6_RS03400 31b0d3d413fe73264876810c6159ec50 750 Gene3D G3DSA:2.170.130.10 1 141 1.1E-29 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS03400 31b0d3d413fe73264876810c6159ec50 750 TIGRFAM TIGR01786 TonB-hemlactrns: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein 9 750 1.9E-120 T 28-03-2018 IPR010949 TonB-dependent haemoglobin/transferrin/lactoferrin receptor GO:0004872|GO:0005215|GO:0006810|GO:0019867 MKLM6_RS03400 31b0d3d413fe73264876810c6159ec50 750 Gene3D G3DSA:2.40.170.20 144 749 9.6E-61 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS03400 31b0d3d413fe73264876810c6159ec50 750 Pfam PF07715 TonB-dependent Receptor Plug Domain 22 130 1.9E-22 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS06685 ec62fedbba88ea435b00ac63fea7f58e 488 Gene3D G3DSA:3.40.80.10 268 487 1.7E-26 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MKLM6_RS06685 ec62fedbba88ea435b00ac63fea7f58e 488 Gene3D G3DSA:3.40.80.10 55 163 7.2E-11 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MKLM6_RS06685 ec62fedbba88ea435b00ac63fea7f58e 488 SUPERFAMILY SSF55846 286 368 9.42E-16 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MKLM6_RS06685 ec62fedbba88ea435b00ac63fea7f58e 488 SUPERFAMILY SSF55846 408 481 9.42E-16 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MKLM6_RS06685 ec62fedbba88ea435b00ac63fea7f58e 488 SUPERFAMILY SSF55846 57 158 6.41E-14 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MKLM6_RS06685 ec62fedbba88ea435b00ac63fea7f58e 488 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 58 147 5.8E-8 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MKLM6_RS06685 ec62fedbba88ea435b00ac63fea7f58e 488 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 289 462 1.4E-14 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MKLM6_RS16990 fce6beba9e569e19fc2fcd189f197305 645 Gene3D G3DSA:3.40.50.300 3 232 5.0E-65 T 28-03-2018 MKLM6_RS16990 fce6beba9e569e19fc2fcd189f197305 645 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS16990 fce6beba9e569e19fc2fcd189f197305 645 Pfam PF00005 ABC transporter 26 174 3.6E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS16990 fce6beba9e569e19fc2fcd189f197305 645 Pfam PF02687 FtsX-like permease family 552 634 2.0E-10 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MKLM6_RS16990 fce6beba9e569e19fc2fcd189f197305 645 SMART SM00382 35 222 2.6E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS16990 fce6beba9e569e19fc2fcd189f197305 645 SUPERFAMILY SSF52540 6 229 1.14E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS16990 fce6beba9e569e19fc2fcd189f197305 645 Pfam PF12704 MacB-like periplasmic core domain 271 490 5.5E-39 T 28-03-2018 IPR025857 MacB-like periplasmic core domain MKLM6_RS03185 7001251c09360825479c002e45eb53da 834 Gene3D G3DSA:3.40.120.10 526 633 4.7E-34 T 28-03-2018 MKLM6_RS03185 7001251c09360825479c002e45eb53da 834 Gene3D G3DSA:3.40.120.10 373 522 3.9E-38 T 28-03-2018 MKLM6_RS03185 7001251c09360825479c002e45eb53da 834 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 471 480 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS03185 7001251c09360825479c002e45eb53da 834 SUPERFAMILY SSF53738 528 628 2.98E-32 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS03185 7001251c09360825479c002e45eb53da 834 SUPERFAMILY SSF53738 630 737 1.18E-28 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS03185 7001251c09360825479c002e45eb53da 834 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 382 511 1.4E-36 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS03185 7001251c09360825479c002e45eb53da 834 Gene3D G3DSA:3.30.310.50 742 834 2.4E-18 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS03185 7001251c09360825479c002e45eb53da 834 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 530 626 7.3E-28 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS03185 7001251c09360825479c002e45eb53da 834 SUPERFAMILY SSF53738 382 503 2.16E-38 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS03185 7001251c09360825479c002e45eb53da 834 Gene3D G3DSA:3.40.120.10 634 741 1.1E-20 T 28-03-2018 MKLM6_RS03185 7001251c09360825479c002e45eb53da 834 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 631 737 5.6E-17 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS03185 7001251c09360825479c002e45eb53da 834 SUPERFAMILY SSF55957 741 834 1.31E-22 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS03185 7001251c09360825479c002e45eb53da 834 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 765 822 1.9E-12 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS03185 7001251c09360825479c002e45eb53da 834 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 543 562 7.6E-24 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS03185 7001251c09360825479c002e45eb53da 834 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 606 621 7.6E-24 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS03185 7001251c09360825479c002e45eb53da 834 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 577 590 7.6E-24 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS03185 7001251c09360825479c002e45eb53da 834 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 470 484 7.6E-24 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS13745 678a003d3f4ed69bc043aade2c58c7cb 335 Pfam PF14841 FliG middle domain 118 188 1.1E-25 T 28-03-2018 IPR032779 Flagellar motor switch protein FliG, middle domain MKLM6_RS13745 678a003d3f4ed69bc043aade2c58c7cb 335 PRINTS PR00954 Flagellar motor switch protein FliG signature 250 270 1.3E-58 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MKLM6_RS13745 678a003d3f4ed69bc043aade2c58c7cb 335 PRINTS PR00954 Flagellar motor switch protein FliG signature 7 23 1.3E-58 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MKLM6_RS13745 678a003d3f4ed69bc043aade2c58c7cb 335 PRINTS PR00954 Flagellar motor switch protein FliG signature 228 248 1.3E-58 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MKLM6_RS13745 678a003d3f4ed69bc043aade2c58c7cb 335 PRINTS PR00954 Flagellar motor switch protein FliG signature 116 139 1.3E-58 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MKLM6_RS13745 678a003d3f4ed69bc043aade2c58c7cb 335 PRINTS PR00954 Flagellar motor switch protein FliG signature 197 222 1.3E-58 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MKLM6_RS13745 678a003d3f4ed69bc043aade2c58c7cb 335 PRINTS PR00954 Flagellar motor switch protein FliG signature 36 62 1.3E-58 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MKLM6_RS13745 678a003d3f4ed69bc043aade2c58c7cb 335 PRINTS PR00954 Flagellar motor switch protein FliG signature 274 300 1.3E-58 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MKLM6_RS13745 678a003d3f4ed69bc043aade2c58c7cb 335 SUPERFAMILY SSF48029 117 327 1.44E-62 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical MKLM6_RS13745 678a003d3f4ed69bc043aade2c58c7cb 335 Pfam PF01706 FliG C-terminal domain 220 326 1.2E-37 T 28-03-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal MKLM6_RS13745 678a003d3f4ed69bc043aade2c58c7cb 335 SUPERFAMILY SSF48029 9 120 6.02E-21 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical MKLM6_RS13745 678a003d3f4ed69bc043aade2c58c7cb 335 Gene3D G3DSA:1.10.220.30 8 71 1.3E-7 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical MKLM6_RS13745 678a003d3f4ed69bc043aade2c58c7cb 335 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 5 333 2.5E-95 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MKLM6_RS13745 678a003d3f4ed69bc043aade2c58c7cb 335 PIRSF PIRSF003161 1 335 6.1E-111 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MKLM6_RS13745 678a003d3f4ed69bc043aade2c58c7cb 335 Pfam PF14842 FliG N-terminal domain 7 107 5.0E-28 T 28-03-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain MKLM6_RS13745 678a003d3f4ed69bc043aade2c58c7cb 335 Gene3D G3DSA:1.10.220.30 74 191 5.1E-20 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical MKLM6_RS13745 678a003d3f4ed69bc043aade2c58c7cb 335 Gene3D G3DSA:1.10.220.30 197 335 1.2E-29 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical MKLM6_RS20575 c01d73299e3bf12570e8cdb12729dfd4 306 SUPERFAMILY SSF53448 2 224 2.63E-39 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS20575 c01d73299e3bf12570e8cdb12729dfd4 306 Pfam PF00535 Glycosyl transferase family 2 3 165 1.5E-34 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MKLM6_RS20575 c01d73299e3bf12570e8cdb12729dfd4 306 Gene3D G3DSA:3.90.550.10 1 237 6.2E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS00510 2ea3163d19c678af925fd85dccb2d583 279 Gene3D G3DSA:3.20.20.100 4 279 2.5E-60 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain MKLM6_RS00510 2ea3163d19c678af925fd85dccb2d583 279 SUPERFAMILY SSF51430 11 278 1.7E-52 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain MKLM6_RS00510 2ea3163d19c678af925fd85dccb2d583 279 Pfam PF00248 Aldo/keto reductase family 23 184 1.9E-18 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain MKLM6_RS00510 2ea3163d19c678af925fd85dccb2d583 279 PRINTS PR00069 Aldo-keto reductase signature 143 160 1.8E-7 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MKLM6_RS00510 2ea3163d19c678af925fd85dccb2d583 279 PRINTS PR00069 Aldo-keto reductase signature 36 60 1.8E-7 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MKLM6_RS00510 2ea3163d19c678af925fd85dccb2d583 279 PRINTS PR00069 Aldo-keto reductase signature 214 238 1.8E-7 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MKLM6_RS14595 47f6f7af6b61ba4dec7b4cc771f7d4b6 409 Pfam PF07670 Nucleoside recognition 50 157 3.9E-10 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 MKLM6_RS14595 47f6f7af6b61ba4dec7b4cc771f7d4b6 409 PIRSF PIRSF036542 1 409 2.8E-183 T 28-03-2018 IPR011415 Predicted bifunctional spore maturation protein, fused SpmA/SpmB MKLM6_RS04430 cc8e5fbdfdaf28bc863831934ec9fd50 404 Pfam PF01494 FAD binding domain 6 342 8.9E-40 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 MKLM6_RS04430 cc8e5fbdfdaf28bc863831934ec9fd50 404 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 296 309 - T 28-03-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 MKLM6_RS04430 cc8e5fbdfdaf28bc863831934ec9fd50 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 158 173 3.8E-20 T 28-03-2018 MKLM6_RS04430 cc8e5fbdfdaf28bc863831934ec9fd50 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 313 3.8E-20 T 28-03-2018 MKLM6_RS04430 cc8e5fbdfdaf28bc863831934ec9fd50 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 297 3.8E-20 T 28-03-2018 MKLM6_RS04430 cc8e5fbdfdaf28bc863831934ec9fd50 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 3.8E-20 T 28-03-2018 MKLM6_RS04430 cc8e5fbdfdaf28bc863831934ec9fd50 404 Gene3D G3DSA:3.50.50.60 3 356 1.5E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS04430 cc8e5fbdfdaf28bc863831934ec9fd50 404 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 6 392 1.5E-121 T 28-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 MKLM6_RS04430 cc8e5fbdfdaf28bc863831934ec9fd50 404 TIGRFAM TIGR01984 UbiH: 2-polyprenyl-6-methoxyphenol 4-hydroxylase 6 392 4.1E-129 T 28-03-2018 IPR011295 2-polyprenyl-6-methoxyphenol 4-hydroxylase GO:0006744|GO:0008681 MKLM6_RS04430 cc8e5fbdfdaf28bc863831934ec9fd50 404 SUPERFAMILY SSF51905 269 386 2.98E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS04430 cc8e5fbdfdaf28bc863831934ec9fd50 404 SUPERFAMILY SSF51905 4 179 2.98E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 Pfam PF00873 AcrB/AcrD/AcrF family 4 1017 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 Gene3D G3DSA:1.20.1640.10 281 502 9.4E-44 T 28-03-2018 MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 Gene3D G3DSA:1.20.1640.10 810 1027 1.8E-36 T 28-03-2018 MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 SUPERFAMILY SSF82714 183 265 2.88E-13 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 Gene3D G3DSA:3.30.2090.10 702 797 6.8E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 3.3E-78 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 3.3E-78 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 3.3E-78 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 PRINTS PR00702 Acriflavin resistance protein family signature 606 620 3.3E-78 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 PRINTS PR00702 Acriflavin resistance protein family signature 542 559 3.3E-78 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 3.3E-78 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 3.3E-78 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 3.3E-78 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 3.3E-78 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 SUPERFAMILY SSF82693 797 844 1.15E-6 T 28-03-2018 MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 SUPERFAMILY SSF82693 658 701 1.15E-6 T 28-03-2018 MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 SUPERFAMILY SSF82866 292 490 1.22E-45 T 28-03-2018 MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 SUPERFAMILY SSF82714 703 793 4.71E-11 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 Gene3D G3DSA:3.30.2090.10 181 270 2.3E-10 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 Gene3D G3DSA:3.30.70.1430 557 652 8.3E-14 T 28-03-2018 MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 Gene3D G3DSA:3.30.70.1430 40 142 4.3E-26 T 28-03-2018 MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 SUPERFAMILY SSF82866 820 1019 5.1E-44 T 28-03-2018 MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 SUPERFAMILY SSF82693 40 131 6.98E-23 T 28-03-2018 MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 SUPERFAMILY SSF82693 555 648 2.09E-14 T 28-03-2018 MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 SUPERFAMILY SSF82693 136 182 9.59E-22 T 28-03-2018 MKLM6_RS09130 5cbf3ca5b498e3d922c29949a5c0cca1 1040 SUPERFAMILY SSF82693 268 324 9.59E-22 T 28-03-2018 MKLM6_RS13480 6e7eec039bcd240d1d7086562b0365fe 70 Gene3D G3DSA:1.10.10.60 5 40 3.9E-9 T 28-03-2018 MKLM6_RS13480 6e7eec039bcd240d1d7086562b0365fe 70 SUPERFAMILY SSF88659 11 39 1.24E-5 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS20220 aa528786fe81b86d6b0a2707cb859eb1 195 Gene3D G3DSA:1.10.10.60 2 52 1.9E-15 T 28-03-2018 MKLM6_RS20220 aa528786fe81b86d6b0a2707cb859eb1 195 SUPERFAMILY SSF46689 4 73 1.8E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS20220 aa528786fe81b86d6b0a2707cb859eb1 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 1.5E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MKLM6_RS20220 aa528786fe81b86d6b0a2707cb859eb1 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 1.5E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MKLM6_RS20220 aa528786fe81b86d6b0a2707cb859eb1 195 SUPERFAMILY SSF48498 77 182 4.04E-16 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MKLM6_RS20220 aa528786fe81b86d6b0a2707cb859eb1 195 Gene3D G3DSA:1.10.357.10 53 183 9.9E-26 T 28-03-2018 MKLM6_RS20220 aa528786fe81b86d6b0a2707cb859eb1 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 54 1.3E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MKLM6_RS14830 b661567e22bb3874a16ae2a0e4fe6589 437 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 325 432 8.9E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14830 b661567e22bb3874a16ae2a0e4fe6589 437 Pfam PF00072 Response regulator receiver domain 51 140 1.2E-4 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14830 b661567e22bb3874a16ae2a0e4fe6589 437 SUPERFAMILY SSF52172 8 173 1.38E-11 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS14830 b661567e22bb3874a16ae2a0e4fe6589 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 432 1.8E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14830 b661567e22bb3874a16ae2a0e4fe6589 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 377 1.8E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14830 b661567e22bb3874a16ae2a0e4fe6589 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 412 1.8E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14830 b661567e22bb3874a16ae2a0e4fe6589 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 391 1.8E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14830 b661567e22bb3874a16ae2a0e4fe6589 437 SMART SM00387 322 435 8.8E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14830 b661567e22bb3874a16ae2a0e4fe6589 437 Gene3D G3DSA:3.30.565.10 285 437 1.6E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14830 b661567e22bb3874a16ae2a0e4fe6589 437 Gene3D G3DSA:3.40.50.2300 2 154 6.7E-16 T 28-03-2018 MKLM6_RS14830 b661567e22bb3874a16ae2a0e4fe6589 437 Gene3D G3DSA:1.10.287.130 163 278 9.4E-5 T 28-03-2018 MKLM6_RS14830 b661567e22bb3874a16ae2a0e4fe6589 437 SUPERFAMILY SSF55874 287 431 1.27E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS10030 da5d35c9d1bd072c307a5023ed07e2b8 180 Pfam PF01613 Flavin reductase like domain 15 151 2.7E-21 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 MKLM6_RS10030 da5d35c9d1bd072c307a5023ed07e2b8 180 SMART SM00903 12 161 1.0E-13 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 MKLM6_RS10030 da5d35c9d1bd072c307a5023ed07e2b8 180 SUPERFAMILY SSF50475 2 160 6.67E-36 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MKLM6_RS10030 da5d35c9d1bd072c307a5023ed07e2b8 180 Gene3D G3DSA:2.30.110.10 1 171 3.8E-34 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MKLM6_RS17680 7190621e37b25e4ccc91d2e327d04349 602 SUPERFAMILY SSF75304 11 448 1.83E-116 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MKLM6_RS17680 7190621e37b25e4ccc91d2e327d04349 602 Pfam PF01425 Amidase 30 443 1.2E-85 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MKLM6_RS17680 7190621e37b25e4ccc91d2e327d04349 602 TIGRFAM TIGR02713 allophanate_hyd: allophanate hydrolase 45 599 4.7E-237 T 28-03-2018 IPR014085 Allophanate hydrolase KEGG: 00220+3.5.1.54|KEGG: 00791+3.5.1.54|MetaCyc: PWY-5169|MetaCyc: PWY-5703 MKLM6_RS17680 7190621e37b25e4ccc91d2e327d04349 602 Gene3D G3DSA:3.10.490.10 473 602 2.2E-28 T 28-03-2018 MKLM6_RS17680 7190621e37b25e4ccc91d2e327d04349 602 Gene3D G3DSA:3.90.1300.10 7 467 1.9E-116 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MKLM6_RS07165 627cdd843faf2224858556d8baa50802 1165 Gene3D G3DSA:1.20.5.50 754 849 0.054 T 28-03-2018 MKLM6_RS07165 627cdd843faf2224858556d8baa50802 1165 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 137 7.9E-33 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal MKLM6_RS07165 627cdd843faf2224858556d8baa50802 1165 Pfam PF02463 RecF/RecN/SMC N terminal domain 663 1149 9.3E-24 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal MKLM6_RS07165 627cdd843faf2224858556d8baa50802 1165 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1158 21.891 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 MKLM6_RS07165 627cdd843faf2224858556d8baa50802 1165 Pfam PF06470 SMC proteins Flexible Hinge Domain 525 573 2.4E-5 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 MKLM6_RS07165 627cdd843faf2224858556d8baa50802 1165 SUPERFAMILY SSF75553 472 663 4.71E-9 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 MKLM6_RS07165 627cdd843faf2224858556d8baa50802 1165 PIRSF PIRSF005719 1 1165 8.5E-260 T 28-03-2018 IPR024704 Structural maintenance of chromosomes protein MKLM6_RS07165 627cdd843faf2224858556d8baa50802 1165 SUPERFAMILY SSF52540 1 216 1.41E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS07165 627cdd843faf2224858556d8baa50802 1165 SUPERFAMILY SSF52540 1055 1141 1.41E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS07165 627cdd843faf2224858556d8baa50802 1165 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1156 0.0 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 MKLM6_RS07165 627cdd843faf2224858556d8baa50802 1165 Gene3D G3DSA:1.20.120.330 359 498 1.4E-4 T 28-03-2018 MKLM6_RS07165 627cdd843faf2224858556d8baa50802 1165 Gene3D G3DSA:3.40.50.300 908 1145 4.6E-21 T 28-03-2018 MKLM6_RS07165 627cdd843faf2224858556d8baa50802 1165 Gene3D G3DSA:1.20.5.340 646 752 0.0094 T 28-03-2018 MKLM6_RS07165 627cdd843faf2224858556d8baa50802 1165 Gene3D G3DSA:3.40.50.300 1 183 2.1E-35 T 28-03-2018 MKLM6_RS18475 2e89a98ae7ebc60fca8580c821e54f85 1358 Gene3D G3DSA:3.90.1100.10 652 719 1.3E-15 T 28-03-2018 MKLM6_RS18475 2e89a98ae7ebc60fca8580c821e54f85 1358 Gene3D G3DSA:3.90.1100.10 436 651 1.4E-76 T 28-03-2018 MKLM6_RS18475 2e89a98ae7ebc60fca8580c821e54f85 1358 Gene3D G3DSA:2.40.50.150 835 1062 2.2E-51 T 28-03-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18475 2e89a98ae7ebc60fca8580c821e54f85 1358 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1082 1094 - T 28-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18475 2e89a98ae7ebc60fca8580c821e54f85 1358 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1354 0.0 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18475 2e89a98ae7ebc60fca8580c821e54f85 1358 Gene3D G3DSA:2.40.50.100 721 801 7.3E-28 T 28-03-2018 MKLM6_RS18475 2e89a98ae7ebc60fca8580c821e54f85 1358 Pfam PF04565 RNA polymerase Rpb2, domain 3 519 586 2.9E-29 T 28-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18475 2e89a98ae7ebc60fca8580c821e54f85 1358 Pfam PF00562 RNA polymerase Rpb2, domain 6 723 1280 1.9E-162 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18475 2e89a98ae7ebc60fca8580c821e54f85 1358 Pfam PF04560 RNA polymerase Rpb2, domain 7 1282 1357 2.1E-26 T 28-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18475 2e89a98ae7ebc60fca8580c821e54f85 1358 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1358 12.358 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18475 2e89a98ae7ebc60fca8580c821e54f85 1358 Pfam PF04561 RNA polymerase Rpb2, domain 2 363 460 3.0E-18 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18475 2e89a98ae7ebc60fca8580c821e54f85 1358 Pfam PF04561 RNA polymerase Rpb2, domain 2 177 230 1.9E-7 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18475 2e89a98ae7ebc60fca8580c821e54f85 1358 Gene3D G3DSA:2.40.270.10 1063 1258 1.0E-80 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18475 2e89a98ae7ebc60fca8580c821e54f85 1358 Gene3D G3DSA:3.90.1800.10 1283 1329 6.3E-12 T 28-03-2018 MKLM6_RS18475 2e89a98ae7ebc60fca8580c821e54f85 1358 Pfam PF04563 RNA polymerase beta subunit 26 505 4.0E-39 T 28-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18475 2e89a98ae7ebc60fca8580c821e54f85 1358 SUPERFAMILY SSF64484 349 945 0.0 T 28-03-2018 MKLM6_RS18475 2e89a98ae7ebc60fca8580c821e54f85 1358 SUPERFAMILY SSF64484 13 232 0.0 T 28-03-2018 MKLM6_RS18475 2e89a98ae7ebc60fca8580c821e54f85 1358 SUPERFAMILY SSF64484 1058 1357 0.0 T 28-03-2018 MKLM6_RS18475 2e89a98ae7ebc60fca8580c821e54f85 1358 Gene3D G3DSA:3.90.1110.10 154 435 1.8E-70 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18475 2e89a98ae7ebc60fca8580c821e54f85 1358 Pfam PF10385 RNA polymerase beta subunit external 1 domain 597 662 5.5E-23 T 28-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS07860 c46df4cf5922de598fd484f19011448d 214 Gene3D G3DSA:1.10.10.10 113 205 4.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS07860 c46df4cf5922de598fd484f19011448d 214 Pfam PF04542 Sigma-70 region 2 46 113 2.3E-18 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS07860 c46df4cf5922de598fd484f19011448d 214 SUPERFAMILY SSF88659 141 202 6.11E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS07860 c46df4cf5922de598fd484f19011448d 214 SUPERFAMILY SSF88946 24 124 4.97E-23 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS07860 c46df4cf5922de598fd484f19011448d 214 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 42 201 1.5E-25 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS07860 c46df4cf5922de598fd484f19011448d 214 Gene3D G3DSA:1.10.1740.10 19 110 6.5E-21 T 28-03-2018 MKLM6_RS07860 c46df4cf5922de598fd484f19011448d 214 Pfam PF08281 Sigma-70, region 4 148 197 1.1E-14 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS05935 f99e9849910e1dec34363300fbb8f990 473 Gene3D G3DSA:3.40.50.720 151 274 2.2E-13 T 28-03-2018 MKLM6_RS05935 f99e9849910e1dec34363300fbb8f990 473 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 27 473 1.7E-140 T 28-03-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase MKLM6_RS05935 f99e9849910e1dec34363300fbb8f990 473 TIGRFAM TIGR03023 WcaJ_sugtrans: undecaprenyl-phosphate glucose phosphotransferase 27 473 2.5E-140 T 28-03-2018 IPR017473 Undecaprenyl-phosphate glucose phosphotransferase, WcaJ MetaCyc: PWY-6655|MetaCyc: PWY-6658 MKLM6_RS05935 f99e9849910e1dec34363300fbb8f990 473 Pfam PF02397 Bacterial sugar transferase 286 465 3.5E-65 T 28-03-2018 IPR003362 Bacterial sugar transferase MKLM6_RS05935 f99e9849910e1dec34363300fbb8f990 473 Pfam PF13727 CoA-binding domain 73 247 1.4E-26 T 28-03-2018 MKLM6_RS12250 fceca880e31a867cefb2777bd7163562 249 Pfam PF17131 Outer membrane lipoprotein-sorting protein 70 246 1.2E-38 T 28-03-2018 IPR033399 Putative outer membrane lipoprotein-sorting protein MKLM6_RS12250 fceca880e31a867cefb2777bd7163562 249 PIRSF PIRSF028205 2 247 5.3E-54 T 28-03-2018 IPR011220 Uncharacterised conserved protein UCP028205 MKLM6_RS12250 fceca880e31a867cefb2777bd7163562 249 Gene3D G3DSA:2.50.20.10 18 248 1.9E-37 T 28-03-2018 MKLM6_RS13520 2a0f934a94f45bfeb55796fc51430c92 423 PIRSF PIRSF000124 5 422 2.7E-52 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MKLM6_RS13520 2a0f934a94f45bfeb55796fc51430c92 423 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 201 289 2.9E-23 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MKLM6_RS13520 2a0f934a94f45bfeb55796fc51430c92 423 SUPERFAMILY SSF51735 6 190 1.38E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS13520 2a0f934a94f45bfeb55796fc51430c92 423 SMART SM00984 316 416 9.3E-35 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MKLM6_RS13520 2a0f934a94f45bfeb55796fc51430c92 423 Gene3D G3DSA:3.40.50.720 4 199 4.1E-40 T 28-03-2018 MKLM6_RS13520 2a0f934a94f45bfeb55796fc51430c92 423 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 316 412 1.3E-21 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MKLM6_RS13520 2a0f934a94f45bfeb55796fc51430c92 423 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 6 179 2.6E-35 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MKLM6_RS13520 2a0f934a94f45bfeb55796fc51430c92 423 PIRSF PIRSF500136 1 423 4.4E-152 T 28-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 MKLM6_RS13520 2a0f934a94f45bfeb55796fc51430c92 423 Gene3D G3DSA:3.40.50.720 223 422 2.1E-56 T 28-03-2018 MKLM6_RS13520 2a0f934a94f45bfeb55796fc51430c92 423 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 6 409 3.2E-122 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MKLM6_RS13520 2a0f934a94f45bfeb55796fc51430c92 423 Gene3D G3DSA:1.20.5.170 200 222 4.8E-11 T 28-03-2018 MKLM6_RS13520 2a0f934a94f45bfeb55796fc51430c92 423 SUPERFAMILY SSF48179 200 290 4.59E-24 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MKLM6_RS13520 2a0f934a94f45bfeb55796fc51430c92 423 SUPERFAMILY SSF52413 299 415 1.09E-29 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 SUPERFAMILY SSF51905 150 308 5.9E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 SUPERFAMILY SSF51905 3 189 5.4E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 559 621 3.2E-10 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 294 1.6E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 Gene3D G3DSA:3.30.413.10 630 815 1.9E-39 T 28-03-2018 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 276 283 2.1E-9 T 28-03-2018 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.1E-9 T 28-03-2018 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 2.1E-9 T 28-03-2018 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 368 383 2.1E-9 T 28-03-2018 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 148 173 2.1E-9 T 28-03-2018 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 631 767 6.3E-20 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 Gene3D G3DSA:3.40.50.720 131 296 1.0E-30 T 28-03-2018 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 Gene3D G3DSA:3.50.50.60 1 130 1.0E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 PIRSF PIRSF037149 1 834 0.0 T 28-03-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 1.6E-17 T 28-03-2018 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 1.6E-17 T 28-03-2018 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.6E-17 T 28-03-2018 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 1.6E-17 T 28-03-2018 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 1.6E-17 T 28-03-2018 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 678 694 - T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 PRINTS PR00397 Sirohaem Fe-binding site signature 678 696 1.2E-6 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 PRINTS PR00397 Sirohaem Fe-binding site signature 635 653 1.2E-6 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 SUPERFAMILY SSF56014 632 808 9.03E-52 T 28-03-2018 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 Pfam PF04324 BFD-like [2Fe-2S] binding domain 423 470 6.6E-10 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 7 799 0.0 T 28-03-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 SUPERFAMILY SSF55124 501 640 1.12E-27 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MKLM6_RS10560 6af54cfece2f87a0dd7516f6464baca2 846 Gene3D G3DSA:3.90.480.10 297 627 5.4E-16 T 28-03-2018 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 SMART SM00091 74 140 0.0034 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 SMART SM00091 188 256 0.0018 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 SMART SM00091 601 670 40.0 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 SMART SM00091 314 384 0.0048 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 PRINTS PR00344 Bacterial sensor protein C-terminal signature 890 904 5.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 PRINTS PR00344 Bacterial sensor protein C-terminal signature 908 918 5.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 PRINTS PR00344 Bacterial sensor protein C-terminal signature 949 962 5.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 PRINTS PR00344 Bacterial sensor protein C-terminal signature 925 943 5.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 SMART SM00086 262 306 6.6E-7 T 28-03-2018 IPR001610 PAC motif MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 SMART SM00086 675 717 0.0023 T 28-03-2018 IPR001610 PAC motif MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 SMART SM00086 393 435 5.7E-4 T 28-03-2018 IPR001610 PAC motif MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 Pfam PF00512 His Kinase A (phospho-acceptor) domain 738 802 1.8E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 849 964 1.4E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 Gene3D G3DSA:3.30.450.40 445 602 3.5E-13 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 Gene3D G3DSA:3.30.565.10 806 973 2.3E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 Gene3D G3DSA:3.30.450.20 72 193 7.3E-11 T 28-03-2018 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 SUPERFAMILY SSF55785 336 437 3.54E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 SMART SM00448 993 1106 3.0E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 SMART SM00387 849 965 7.1E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 SUPERFAMILY SSF55781 454 600 1.79E-11 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 Pfam PF08447 PAS fold 624 711 3.1E-10 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 Pfam PF08447 PAS fold 340 428 1.2E-12 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 Pfam PF08447 PAS fold 213 300 1.8E-20 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 Pfam PF01627 Hpt domain 1155 1231 4.1E-10 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 Pfam PF00072 Response regulator receiver domain 995 1106 1.6E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 SUPERFAMILY SSF55874 791 963 1.57E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 Gene3D G3DSA:1.20.120.160 1136 1326 5.4E-15 T 28-03-2018 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 Gene3D G3DSA:1.10.287.130 734 798 5.3E-21 T 28-03-2018 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 SMART SM00065 453 597 0.0072 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 SUPERFAMILY SSF47226 1089 1102 1.02E-17 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 SUPERFAMILY SSF47226 1134 1220 1.02E-17 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 SUPERFAMILY SSF55785 87 190 9.95E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 SUPERFAMILY SSF55785 623 725 1.41E-12 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 Gene3D G3DSA:3.30.450.20 611 657 1.3E-10 T 28-03-2018 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 Pfam PF13426 PAS domain 86 185 0.47 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 SUPERFAMILY SSF55785 195 308 1.77E-21 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 Gene3D G3DSA:3.30.450.20 658 733 1.1E-8 T 28-03-2018 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 SUPERFAMILY SSF47384 722 804 2.75E-22 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 SMART SM00388 737 802 2.5E-24 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 Gene3D G3DSA:3.30.450.20 322 444 1.7E-18 T 28-03-2018 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 Gene3D G3DSA:3.30.450.20 194 321 1.8E-23 T 28-03-2018 MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 213 313 2.8E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 86 190 3.9E-6 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 343 441 3.1E-8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 SUPERFAMILY SSF52172 992 1118 9.39E-39 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS07230 bf6f128664fd32da545566eae05a6762 1329 Gene3D G3DSA:3.40.50.2300 989 1122 3.4E-41 T 28-03-2018 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 Gene3D G3DSA:1.10.287.130 332 389 7.7E-21 T 28-03-2018 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 SMART SM00267 1245 1417 1.8E-63 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 SUPERFAMILY SSF141868 1432 1679 3.4E-83 T 28-03-2018 IPR001633 EAL domain MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 1253 1416 3.3E-45 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 Gene3D G3DSA:3.20.20.450 1420 1674 5.6E-90 T 28-03-2018 IPR001633 EAL domain MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 SMART SM00304 228 281 6.4E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 SMART SM00388 328 393 5.1E-25 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 SMART SM00448 575 693 1.9E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 SMART SM00448 721 837 1.8E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 SMART SM00448 1001 1114 2.4E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 440 556 5.2E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 Gene3D G3DSA:3.30.450.20 164 331 0.0028 T 28-03-2018 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 Pfam PF01627 Hpt domain 891 972 1.8E-9 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 PRINTS PR00344 Bacterial sensor protein C-terminal signature 501 511 6.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 PRINTS PR00344 Bacterial sensor protein C-terminal signature 483 497 6.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 PRINTS PR00344 Bacterial sensor protein C-terminal signature 542 555 6.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 536 6.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 Gene3D G3DSA:3.30.70.270 1253 1419 2.0E-58 T 28-03-2018 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 Gene3D G3DSA:3.30.450.20 1131 1252 1.3E-10 T 28-03-2018 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 SUPERFAMILY SSF47226 820 833 2.49E-21 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 SUPERFAMILY SSF47226 868 968 2.49E-21 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 Gene3D G3DSA:3.30.565.10 398 562 4.7E-47 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 Gene3D G3DSA:3.40.50.2300 570 713 2.3E-26 T 28-03-2018 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 SUPERFAMILY SSF55073 1261 1419 1.1E-48 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 SUPERFAMILY SSF47384 316 394 1.04E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 Pfam PF00512 His Kinase A (phospho-acceptor) domain 328 393 6.6E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 SUPERFAMILY SSF55785 1124 1243 5.5E-8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 Pfam PF00072 Response regulator receiver domain 577 692 1.7E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 Pfam PF00072 Response regulator receiver domain 723 836 1.1E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 Pfam PF00072 Response regulator receiver domain 1004 1114 2.2E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 SUPERFAMILY SSF52172 572 697 4.27E-26 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 Pfam PF00990 Diguanylate cyclase, GGDEF domain 1256 1413 2.3E-49 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 SUPERFAMILY SSF52172 1002 1135 1.04E-35 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 Gene3D G3DSA:3.40.50.2300 998 1130 3.9E-34 T 28-03-2018 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 Gene3D G3DSA:3.40.50.2300 714 854 5.5E-37 T 28-03-2018 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 SMART SM00052 1427 1671 2.9E-103 T 28-03-2018 IPR001633 EAL domain MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 SMART SM00073 880 977 4.3E-7 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 Pfam PF17152 Periplasmic sensor domain 42 109 1.1E-16 T 28-03-2018 IPR033417 Periplasmic sensor domain CHASE8 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 SUPERFAMILY SSF52172 722 842 1.42E-33 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 SMART SM00387 440 558 3.6E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 Pfam PF00563 EAL domain 1433 1666 1.3E-70 T 28-03-2018 IPR001633 EAL domain MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 Gene3D G3DSA:1.20.120.160 868 981 7.1E-16 T 28-03-2018 MKLM6_RS11995 bd3c854ab18ade1de416594de72d5e66 1697 SUPERFAMILY SSF55874 382 554 1.7E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS06925 8f23aa843a7855aeb58994217e99074a 337 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 153 160 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS06925 8f23aa843a7855aeb58994217e99074a 337 SMART SM00846 3 155 1.2E-96 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS06925 8f23aa843a7855aeb58994217e99074a 337 SUPERFAMILY SSF55347 155 317 1.16E-68 T 28-03-2018 MKLM6_RS06925 8f23aa843a7855aeb58994217e99074a 337 Gene3D G3DSA:3.40.50.720 1 164 7.1E-76 T 28-03-2018 MKLM6_RS06925 8f23aa843a7855aeb58994217e99074a 337 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 106 8.9E-39 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS06925 8f23aa843a7855aeb58994217e99074a 337 SUPERFAMILY SSF51735 1 183 3.13E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS06925 8f23aa843a7855aeb58994217e99074a 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 149 167 1.1E-38 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS06925 8f23aa843a7855aeb58994217e99074a 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 272 287 1.1E-38 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS06925 8f23aa843a7855aeb58994217e99074a 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 232 249 1.1E-38 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS06925 8f23aa843a7855aeb58994217e99074a 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 176 192 1.1E-38 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS06925 8f23aa843a7855aeb58994217e99074a 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 112 125 1.1E-38 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS06925 8f23aa843a7855aeb58994217e99074a 337 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 160 316 1.2E-62 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS06925 8f23aa843a7855aeb58994217e99074a 337 Gene3D G3DSA:3.30.360.10 165 318 6.5E-63 T 28-03-2018 MKLM6_RS06925 8f23aa843a7855aeb58994217e99074a 337 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 328 1.7E-128 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS06925 8f23aa843a7855aeb58994217e99074a 337 PIRSF PIRSF000149 1 337 8.8E-137 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS04460 ab0f875a068d8b5c001da35d3550badc 435 SUPERFAMILY SSF52540 12 233 1.56E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS04460 ab0f875a068d8b5c001da35d3550badc 435 Gene3D G3DSA:3.40.50.300 2 152 1.6E-28 T 28-03-2018 MKLM6_RS04460 ab0f875a068d8b5c001da35d3550badc 435 Pfam PF16193 AAA C-terminal domain 187 265 1.0E-23 T 28-03-2018 IPR032423 AAA C-terminal domain MKLM6_RS04460 ab0f875a068d8b5c001da35d3550badc 435 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 52 158 2.2E-15 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MKLM6_RS04460 ab0f875a068d8b5c001da35d3550badc 435 Pfam PF12002 MgsA AAA+ ATPase C terminal 266 431 3.1E-68 T 28-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal MKLM6_RS04460 ab0f875a068d8b5c001da35d3550badc 435 Gene3D G3DSA:1.10.8.60 153 240 2.4E-19 T 28-03-2018 MKLM6_RS04460 ab0f875a068d8b5c001da35d3550badc 435 Gene3D G3DSA:1.10.3710.10 346 435 1.3E-32 T 28-03-2018 MKLM6_RS04460 ab0f875a068d8b5c001da35d3550badc 435 SUPERFAMILY SSF48019 250 432 6.23E-76 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MKLM6_RS04460 ab0f875a068d8b5c001da35d3550badc 435 Gene3D G3DSA:1.20.272.10 250 344 9.9E-38 T 28-03-2018 MKLM6_RS04460 ab0f875a068d8b5c001da35d3550badc 435 SMART SM00382 47 165 2.1E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS02025 45e80baaf22868bf3c36ef825de4eb47 1034 Pfam PF00873 AcrB/AcrD/AcrF family 17 1031 2.4E-150 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS02025 45e80baaf22868bf3c36ef825de4eb47 1034 Gene3D G3DSA:3.30.70.1430 568 677 4.0E-7 T 28-03-2018 MKLM6_RS02025 45e80baaf22868bf3c36ef825de4eb47 1034 SUPERFAMILY SSF82866 807 1034 4.19E-39 T 28-03-2018 MKLM6_RS02025 45e80baaf22868bf3c36ef825de4eb47 1034 SUPERFAMILY SSF82866 297 493 5.36E-37 T 28-03-2018 MKLM6_RS02025 45e80baaf22868bf3c36ef825de4eb47 1034 SUPERFAMILY SSF82714 190 274 1.29E-13 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS02025 45e80baaf22868bf3c36ef825de4eb47 1034 Gene3D G3DSA:3.30.2090.10 188 273 2.2E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS02025 45e80baaf22868bf3c36ef825de4eb47 1034 Gene3D G3DSA:3.30.2090.10 723 810 1.7E-12 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS02025 45e80baaf22868bf3c36ef825de4eb47 1034 Gene3D G3DSA:1.20.1640.10 811 1034 4.2E-35 T 28-03-2018 MKLM6_RS02025 45e80baaf22868bf3c36ef825de4eb47 1034 Gene3D G3DSA:1.20.1640.10 274 494 5.6E-38 T 28-03-2018 MKLM6_RS02025 45e80baaf22868bf3c36ef825de4eb47 1034 SUPERFAMILY SSF82693 276 330 2.88E-11 T 28-03-2018 MKLM6_RS02025 45e80baaf22868bf3c36ef825de4eb47 1034 SUPERFAMILY SSF82693 148 189 2.88E-11 T 28-03-2018 MKLM6_RS02025 45e80baaf22868bf3c36ef825de4eb47 1034 SUPERFAMILY SSF82693 50 140 1.94E-13 T 28-03-2018 MKLM6_RS02025 45e80baaf22868bf3c36ef825de4eb47 1034 Gene3D G3DSA:3.30.70.1430 51 151 8.5E-15 T 28-03-2018 MKLM6_RS02025 45e80baaf22868bf3c36ef825de4eb47 1034 SUPERFAMILY SSF82714 728 807 3.27E-10 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS02025 45e80baaf22868bf3c36ef825de4eb47 1034 PRINTS PR00702 Acriflavin resistance protein family signature 469 492 1.1E-27 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS02025 45e80baaf22868bf3c36ef825de4eb47 1034 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 1.1E-27 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS02025 45e80baaf22868bf3c36ef825de4eb47 1034 PRINTS PR00702 Acriflavin resistance protein family signature 444 467 1.1E-27 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS02025 45e80baaf22868bf3c36ef825de4eb47 1034 PRINTS PR00702 Acriflavin resistance protein family signature 48 66 1.1E-27 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS02025 45e80baaf22868bf3c36ef825de4eb47 1034 PRINTS PR00702 Acriflavin resistance protein family signature 390 414 1.1E-27 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS02025 45e80baaf22868bf3c36ef825de4eb47 1034 PRINTS PR00702 Acriflavin resistance protein family signature 20 44 1.1E-27 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS15325 cdaae58bb441677d68c8ad3743cfeea8 451 Gene3D G3DSA:3.40.50.980 99 281 6.1E-11 T 28-03-2018 MKLM6_RS15325 cdaae58bb441677d68c8ad3743cfeea8 451 Pfam PF00501 AMP-binding enzyme 196 313 1.0E-8 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MKLM6_RS15325 cdaae58bb441677d68c8ad3743cfeea8 451 Gene3D G3DSA:2.30.38.10 286 319 0.026 T 28-03-2018 MKLM6_RS15325 cdaae58bb441677d68c8ad3743cfeea8 451 SUPERFAMILY SSF56801 49 444 1.57E-23 T 28-03-2018 MKLM6_RS02340 c033d4c9ca5dfceac0df54f7bb801ed2 249 Gene3D G3DSA:3.30.230.70 1 241 2.8E-57 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MKLM6_RS02340 c033d4c9ca5dfceac0df54f7bb801ed2 249 Hamap MF_00564 Ribonuclease PH [rph]. 1 237 47.933 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 MKLM6_RS02340 c033d4c9ca5dfceac0df54f7bb801ed2 249 SUPERFAMILY SSF55666 153 242 8.25E-24 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MKLM6_RS02340 c033d4c9ca5dfceac0df54f7bb801ed2 249 SUPERFAMILY SSF54211 1 181 6.07E-45 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS02340 c033d4c9ca5dfceac0df54f7bb801ed2 249 Pfam PF01138 3' exoribonuclease family, domain 1 10 139 1.6E-21 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MKLM6_RS02340 c033d4c9ca5dfceac0df54f7bb801ed2 249 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 28-03-2018 IPR018336 Ribonuclease PH, conserved site MKLM6_RS02340 c033d4c9ca5dfceac0df54f7bb801ed2 249 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 236 2.4E-115 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 MKLM6_RS02340 c033d4c9ca5dfceac0df54f7bb801ed2 249 Pfam PF03725 3' exoribonuclease family, domain 2 159 222 1.1E-9 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MKLM6_RS22085 ed02b9196d0c8d1c485a808586b333e6 321 TIGRFAM TIGR01913 bet_lambda: phage recombination protein Bet 28 199 1.9E-23 T 28-03-2018 IPR010183 Bacteriophage lambda, Bet MKLM6_RS22085 ed02b9196d0c8d1c485a808586b333e6 321 Pfam PF03837 RecT family 28 200 3.8E-16 T 28-03-2018 IPR018330 RecT family GO:0003677|GO:0006259 MKLM6_RS22325 5865ca65ffcded80e56284f1d2779b47 1152 SUPERFAMILY SSF52540 114 123 1.54E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS22325 5865ca65ffcded80e56284f1d2779b47 1152 SUPERFAMILY SSF52540 1041 1139 1.54E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS22325 5865ca65ffcded80e56284f1d2779b47 1152 SUPERFAMILY SSF52540 1 84 1.54E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS22325 5865ca65ffcded80e56284f1d2779b47 1152 Gene3D G3DSA:3.40.50.300 1 1145 2.1E-15 T 28-03-2018 MKLM6_RS22325 5865ca65ffcded80e56284f1d2779b47 1152 Pfam PF13514 AAA domain 1 206 6.1E-75 T 28-03-2018 MKLM6_RS19520 0f8d147d2d2d71789a7c44b2f76a6662 670 Gene3D G3DSA:3.40.50.970 344 538 1.3E-49 T 28-03-2018 MKLM6_RS19520 0f8d147d2d2d71789a7c44b2f76a6662 670 Gene3D G3DSA:3.40.50.970 5 343 1.5E-46 T 28-03-2018 MKLM6_RS19520 0f8d147d2d2d71789a7c44b2f76a6662 670 Pfam PF02780 Transketolase, C-terminal domain 549 662 3.4E-16 T 28-03-2018 IPR033248 Transketolase, C-terminal domain MKLM6_RS19520 0f8d147d2d2d71789a7c44b2f76a6662 670 Pfam PF00676 Dehydrogenase E1 component 42 289 1.1E-35 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 MKLM6_RS19520 0f8d147d2d2d71789a7c44b2f76a6662 670 Gene3D G3DSA:3.40.50.920 542 670 3.8E-20 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MKLM6_RS19520 0f8d147d2d2d71789a7c44b2f76a6662 670 SUPERFAMILY SSF52518 31 331 4.57E-55 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS19520 0f8d147d2d2d71789a7c44b2f76a6662 670 SMART SM00861 345 520 1.6E-45 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MKLM6_RS19520 0f8d147d2d2d71789a7c44b2f76a6662 670 Pfam PF02779 Transketolase, pyrimidine binding domain 346 519 9.7E-38 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MKLM6_RS19520 0f8d147d2d2d71789a7c44b2f76a6662 670 SUPERFAMILY SSF52922 548 669 3.93E-20 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MKLM6_RS19520 0f8d147d2d2d71789a7c44b2f76a6662 670 SUPERFAMILY SSF52518 346 523 3.13E-50 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS11830 a8b6e853aefe6cbb633e81ae7382d53c 570 Gene3D G3DSA:3.40.50.300 292 570 9.0E-68 T 28-03-2018 MKLM6_RS11830 a8b6e853aefe6cbb633e81ae7382d53c 570 Gene3D G3DSA:3.30.450.90 154 291 2.4E-48 T 28-03-2018 MKLM6_RS11830 a8b6e853aefe6cbb633e81ae7382d53c 570 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 88 567 3.2E-200 T 28-03-2018 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 MKLM6_RS11830 a8b6e853aefe6cbb633e81ae7382d53c 570 SUPERFAMILY SSF52540 174 567 4.6E-102 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS11830 a8b6e853aefe6cbb633e81ae7382d53c 570 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 386 400 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 MKLM6_RS11830 a8b6e853aefe6cbb633e81ae7382d53c 570 SUPERFAMILY SSF160246 12 151 6.28E-21 T 28-03-2018 MKLM6_RS11830 a8b6e853aefe6cbb633e81ae7382d53c 570 SMART SM00382 319 440 2.5E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS11830 a8b6e853aefe6cbb633e81ae7382d53c 570 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 49 154 1.3E-7 T 28-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 MKLM6_RS11830 a8b6e853aefe6cbb633e81ae7382d53c 570 Pfam PF00437 Type II/IV secretion system protein 193 458 1.5E-86 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 MKLM6_RS22685 5886139fe205ea3031457b67750e48a7 436 Pfam PF00817 impB/mucB/samB family 20 163 3.2E-30 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MKLM6_RS22685 5886139fe205ea3031457b67750e48a7 436 SUPERFAMILY SSF56672 16 250 2.22E-66 T 28-03-2018 MKLM6_RS22685 5886139fe205ea3031457b67750e48a7 436 Gene3D G3DSA:3.30.1490.100 260 376 4.6E-23 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MKLM6_RS22685 5886139fe205ea3031457b67750e48a7 436 Pfam PF13438 Domain of unknown function (DUF4113) 385 433 2.4E-15 T 28-03-2018 IPR025188 Domain of unknown function DUF4113 MKLM6_RS22685 5886139fe205ea3031457b67750e48a7 436 SUPERFAMILY SSF100879 263 361 1.02E-7 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MKLM6_RS22685 5886139fe205ea3031457b67750e48a7 436 Pfam PF11799 impB/mucB/samB family C-terminal domain 257 364 5.5E-15 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MKLM6_RS22685 5886139fe205ea3031457b67750e48a7 436 Gene3D G3DSA:3.30.70.270 52 130 9.3E-18 T 28-03-2018 MKLM6_RS22685 5886139fe205ea3031457b67750e48a7 436 Gene3D G3DSA:3.30.70.270 131 186 2.9E-9 T 28-03-2018 MKLM6_RS22685 5886139fe205ea3031457b67750e48a7 436 Gene3D G3DSA:1.10.150.20 187 259 4.1E-15 T 28-03-2018 MKLM6_RS16190 de3f44b9064d9b66974ea25d39553818 377 Pfam PF00266 Aminotransferase class-V 13 344 5.6E-51 T 28-03-2018 IPR000192 Aminotransferase class V domain MKLM6_RS16190 de3f44b9064d9b66974ea25d39553818 377 Gene3D G3DSA:3.90.1150.10 267 373 4.6E-13 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS16190 de3f44b9064d9b66974ea25d39553818 377 Gene3D G3DSA:3.40.640.10 15 266 1.1E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS16190 de3f44b9064d9b66974ea25d39553818 377 SUPERFAMILY SSF53383 5 368 1.91E-78 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS21465 80839aa348cb39050a63119f79fbb42b 208 SUPERFAMILY SSF141523 48 109 4.71E-17 T 28-03-2018 MKLM6_RS21465 80839aa348cb39050a63119f79fbb42b 208 SUPERFAMILY SSF141523 159 207 4.71E-17 T 28-03-2018 MKLM6_RS21465 80839aa348cb39050a63119f79fbb42b 208 Gene3D G3DSA:2.40.440.10 50 208 8.4E-20 T 28-03-2018 MKLM6_RS21465 80839aa348cb39050a63119f79fbb42b 208 Pfam PF03734 L,D-transpeptidase catalytic domain 52 207 9.7E-17 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MKLM6_RS11745 f9b0f3256398b1d1311e2c14e3101a42 300 Pfam PF02310 B12 binding domain 176 266 2.9E-7 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MKLM6_RS11745 f9b0f3256398b1d1311e2c14e3101a42 300 Gene3D G3DSA:1.10.1240.10 104 167 5.5E-7 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MKLM6_RS11745 f9b0f3256398b1d1311e2c14e3101a42 300 Gene3D G3DSA:1.10.1660.10 1 103 3.2E-15 T 28-03-2018 MKLM6_RS11745 f9b0f3256398b1d1311e2c14e3101a42 300 Gene3D G3DSA:3.40.50.280 170 290 6.9E-14 T 28-03-2018 MKLM6_RS11745 f9b0f3256398b1d1311e2c14e3101a42 300 SUPERFAMILY SSF47644 86 147 1.44E-6 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MKLM6_RS11745 f9b0f3256398b1d1311e2c14e3101a42 300 SMART SM00422 2 68 2.9E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MKLM6_RS11745 f9b0f3256398b1d1311e2c14e3101a42 300 SUPERFAMILY SSF46955 1 83 3.34E-14 T 28-03-2018 IPR009061 Putative DNA-binding domain MKLM6_RS11745 f9b0f3256398b1d1311e2c14e3101a42 300 SUPERFAMILY SSF52242 170 265 1.11E-13 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MKLM6_RS11745 f9b0f3256398b1d1311e2c14e3101a42 300 Pfam PF02607 B12 binding domain 92 159 1.5E-13 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MKLM6_RS11745 f9b0f3256398b1d1311e2c14e3101a42 300 Pfam PF13411 MerR HTH family regulatory protein 2 63 2.0E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MKLM6_RS02860 23d0e98de739b4402b4be605190a6219 187 Pfam PF05685 Putative restriction endonuclease 12 163 2.2E-32 T 28-03-2018 IPR008538 Domain of unknown function DUF820 MKLM6_RS02860 23d0e98de739b4402b4be605190a6219 187 SUPERFAMILY SSF52980 3 181 8.58E-24 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MKLM6_RS02860 23d0e98de739b4402b4be605190a6219 187 Gene3D G3DSA:3.90.1570.10 1 185 2.2E-40 T 28-03-2018 MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 SUPERFAMILY SSF55785 11 122 1.96E-21 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 Gene3D G3DSA:3.30.450.20 510 654 4.4E-20 T 28-03-2018 MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 Pfam PF01590 GAF domain 158 312 7.2E-17 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 Gene3D G3DSA:3.20.20.450 829 1083 8.1E-102 T 28-03-2018 IPR001633 EAL domain MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 SUPERFAMILY SSF55781 143 325 1.29E-54 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 SMART SM00091 22 88 30.0 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 SMART SM00091 529 595 0.0017 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 SMART SM00267 643 820 1.5E-67 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 Gene3D G3DSA:3.30.70.270 655 828 1.5E-60 T 28-03-2018 MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 Gene3D G3DSA:3.30.450.20 2 123 2.8E-16 T 28-03-2018 MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 Pfam PF00360 Phytochrome region 347 511 1.1E-39 T 28-03-2018 IPR013515 Phytochrome, central region GO:0006355|GO:0009584|GO:0018298 MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 SMART SM00052 830 1076 3.8E-114 T 28-03-2018 IPR001633 EAL domain MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 SUPERFAMILY SSF55781 350 509 1.67E-42 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 Pfam PF13426 PAS domain 540 641 9.4E-12 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 SUPERFAMILY SSF55785 540 652 4.06E-19 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 Pfam PF00990 Diguanylate cyclase, GGDEF domain 654 815 4.3E-50 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 SMART SM00065 153 327 6.3E-9 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 PRINTS PR01033 Phytochrome signature 437 456 1.8E-14 T 28-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 PRINTS PR01033 Phytochrome signature 255 276 1.8E-14 T 28-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 PRINTS PR01033 Phytochrome signature 168 187 1.8E-14 T 28-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 PRINTS PR01033 Phytochrome signature 472 490 1.8E-14 T 28-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 PRINTS PR01033 Phytochrome signature 352 372 1.8E-14 T 28-03-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 SUPERFAMILY SSF55073 659 822 5.76E-51 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 Pfam PF08446 PAS fold 16 122 3.1E-14 T 28-03-2018 IPR013654 PAS fold-2 GO:0006355 MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 535 649 1.6E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 650 819 3.5E-43 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 SUPERFAMILY SSF141868 836 1082 1.96E-88 T 28-03-2018 IPR001633 EAL domain MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 Pfam PF00563 EAL domain 836 1071 1.6E-71 T 28-03-2018 IPR001633 EAL domain MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 SMART SM00086 601 643 2.2E-5 T 28-03-2018 IPR001610 PAC motif MKLM6_RS09000 7453e251d007ddd0d9cb267bbff34aec 1083 Gene3D G3DSA:3.30.450.40 124 321 2.6E-36 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS03850 ad0363357cd4596cd38f679d92a1a524 527 Gene3D G3DSA:3.30.70.260 449 525 1.2E-14 T 28-03-2018 MKLM6_RS03850 ad0363357cd4596cd38f679d92a1a524 527 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 3 527 2.3E-185 T 28-03-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 MKLM6_RS03850 ad0363357cd4596cd38f679d92a1a524 527 Gene3D G3DSA:3.40.50.720 108 283 4.8E-57 T 28-03-2018 MKLM6_RS03850 ad0363357cd4596cd38f679d92a1a524 527 Pfam PF01842 ACT domain 455 510 3.4E-9 T 28-03-2018 IPR002912 ACT domain MKLM6_RS03850 ad0363357cd4596cd38f679d92a1a524 527 Gene3D G3DSA:3.30.1330.90 317 448 2.5E-29 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 MKLM6_RS03850 ad0363357cd4596cd38f679d92a1a524 527 SUPERFAMILY SSF143548 319 449 2.48E-28 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 MKLM6_RS03850 ad0363357cd4596cd38f679d92a1a524 527 SUPERFAMILY SSF52283 1 135 1.63E-36 T 28-03-2018 MKLM6_RS03850 ad0363357cd4596cd38f679d92a1a524 527 SUPERFAMILY SSF51735 102 282 8.01E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS03850 ad0363357cd4596cd38f679d92a1a524 527 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 313 2.7E-37 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 MKLM6_RS03850 ad0363357cd4596cd38f679d92a1a524 527 Gene3D G3DSA:3.40.50.720 1 107 6.1E-34 T 28-03-2018 MKLM6_RS03850 ad0363357cd4596cd38f679d92a1a524 527 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 221 237 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MKLM6_RS03850 ad0363357cd4596cd38f679d92a1a524 527 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 281 2.0E-63 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MKLM6_RS03850 ad0363357cd4596cd38f679d92a1a524 527 SUPERFAMILY SSF55021 444 525 4.96E-15 T 28-03-2018 MKLM6_RS11085 9b14d0ca73167a1154dbf888e3903571 293 Gene3D G3DSA:3.90.550.10 1 293 1.1E-55 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS11085 9b14d0ca73167a1154dbf888e3903571 293 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 5 266 5.1E-110 T 28-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 MKLM6_RS11085 9b14d0ca73167a1154dbf888e3903571 293 Pfam PF00483 Nucleotidyl transferase 11 263 2.7E-27 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MKLM6_RS11085 9b14d0ca73167a1154dbf888e3903571 293 SUPERFAMILY SSF53448 5 279 3.83E-61 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS04400 b71caf1b4296c1f5329e889dfecf3888 453 Pfam PF13844 Glycosyl transferase family 41 85 231 8.2E-43 T 28-03-2018 IPR029489 O-GlcNAc transferase, C-terminal Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 MKLM6_RS04400 b71caf1b4296c1f5329e889dfecf3888 453 Pfam PF13844 Glycosyl transferase family 41 244 437 1.1E-51 T 28-03-2018 IPR029489 O-GlcNAc transferase, C-terminal Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 MKLM6_RS04400 b71caf1b4296c1f5329e889dfecf3888 453 Gene3D G3DSA:3.40.50.2000 231 420 3.8E-27 T 28-03-2018 MKLM6_RS04400 b71caf1b4296c1f5329e889dfecf3888 453 SUPERFAMILY SSF53756 100 429 3.45E-6 T 28-03-2018 MKLM6_RS11050 f8a16d903ddb861e0551a5165ccf9d7c 294 Gene3D G3DSA:3.40.190.10 178 263 3.1E-23 T 28-03-2018 MKLM6_RS11050 f8a16d903ddb861e0551a5165ccf9d7c 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 5.0E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS11050 f8a16d903ddb861e0551a5165ccf9d7c 294 SUPERFAMILY SSF46785 4 87 1.65E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS11050 f8a16d903ddb861e0551a5165ccf9d7c 294 SUPERFAMILY SSF53850 90 293 5.43E-39 T 28-03-2018 MKLM6_RS11050 f8a16d903ddb861e0551a5165ccf9d7c 294 Pfam PF03466 LysR substrate binding domain 89 291 1.3E-35 T 28-03-2018 IPR005119 LysR, substrate-binding MKLM6_RS11050 f8a16d903ddb861e0551a5165ccf9d7c 294 Gene3D G3DSA:1.10.10.10 3 90 1.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS11050 f8a16d903ddb861e0551a5165ccf9d7c 294 Gene3D G3DSA:3.40.190.10 91 177 1.6E-10 T 28-03-2018 MKLM6_RS19545 1c9f0047a87af8832a58ade819ed31df 112 ProSitePatterns PS00892 HIT domain signature. 85 103 - T 28-03-2018 IPR019808 Histidine triad, conserved site MKLM6_RS19545 1c9f0047a87af8832a58ade819ed31df 112 Gene3D G3DSA:3.30.428.10 3 109 1.9E-31 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 MKLM6_RS19545 1c9f0047a87af8832a58ade819ed31df 112 Pfam PF01230 HIT domain 12 106 5.0E-27 T 28-03-2018 IPR001310 Histidine triad (HIT) protein MKLM6_RS19545 1c9f0047a87af8832a58ade819ed31df 112 SUPERFAMILY SSF54197 1 111 1.55E-36 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 MKLM6_RS19545 1c9f0047a87af8832a58ade819ed31df 112 PRINTS PR00332 Histidine triad family signature 26 44 1.4E-16 T 28-03-2018 IPR001310 Histidine triad (HIT) protein MKLM6_RS19545 1c9f0047a87af8832a58ade819ed31df 112 PRINTS PR00332 Histidine triad family signature 5 21 1.4E-16 T 28-03-2018 IPR001310 Histidine triad (HIT) protein MKLM6_RS19545 1c9f0047a87af8832a58ade819ed31df 112 PRINTS PR00332 Histidine triad family signature 92 102 1.4E-16 T 28-03-2018 IPR001310 Histidine triad (HIT) protein MKLM6_RS10380 fd28755a553ace950071e6319ba66127 508 Gene3D G3DSA:2.40.160.50 119 508 2.6E-41 T 28-03-2018 MKLM6_RS10380 fd28755a553ace950071e6319ba66127 508 Gene3D G3DSA:3.10.20.310 16 88 2.9E-14 T 28-03-2018 MKLM6_RS10380 fd28755a553ace950071e6319ba66127 508 Pfam PF08479 POTRA domain, ShlB-type 15 88 9.9E-17 T 28-03-2018 IPR013686 Polypeptide-transport-associated, ShlB-type MKLM6_RS10380 fd28755a553ace950071e6319ba66127 508 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 154 471 1.1E-19 T 28-03-2018 IPR005565 Haemolysin activator HlyB, C-terminal MKLM6_RS02475 3dda2529a825ade954a56a0800908310 189 Gene3D G3DSA:1.10.340.30 2 183 9.7E-81 T 28-03-2018 MKLM6_RS02475 3dda2529a825ade954a56a0800908310 189 Pfam PF03352 Methyladenine glycosylase 7 183 5.0E-79 T 28-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 MKLM6_RS02475 3dda2529a825ade954a56a0800908310 189 SUPERFAMILY SSF48150 4 186 1.62E-77 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MKLM6_RS21790 e042098dcfc782f61b523ff94fc2ee06 367 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 366 9.6E-103 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS21790 e042098dcfc782f61b523ff94fc2ee06 367 PIRSF PIRSF000804 1 367 2.3E-112 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS21790 e042098dcfc782f61b523ff94fc2ee06 367 Gene3D G3DSA:3.10.150.10 250 367 2.2E-22 T 28-03-2018 MKLM6_RS21790 e042098dcfc782f61b523ff94fc2ee06 367 SUPERFAMILY SSF55979 1 119 2.86E-29 T 28-03-2018 MKLM6_RS21790 e042098dcfc782f61b523ff94fc2ee06 367 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 248 366 6.4E-27 T 28-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS21790 e042098dcfc782f61b523ff94fc2ee06 367 Pfam PF02767 DNA polymerase III beta subunit, central domain 130 244 3.4E-30 T 28-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS21790 e042098dcfc782f61b523ff94fc2ee06 367 SUPERFAMILY SSF55979 248 366 7.33E-29 T 28-03-2018 MKLM6_RS21790 e042098dcfc782f61b523ff94fc2ee06 367 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 119 4.1E-38 T 28-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS21790 e042098dcfc782f61b523ff94fc2ee06 367 SMART SM00480 17 363 3.2E-123 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS21790 e042098dcfc782f61b523ff94fc2ee06 367 SUPERFAMILY SSF55979 126 245 2.49E-28 T 28-03-2018 MKLM6_RS21790 e042098dcfc782f61b523ff94fc2ee06 367 Gene3D G3DSA:3.10.150.10 124 248 8.9E-30 T 28-03-2018 MKLM6_RS21790 e042098dcfc782f61b523ff94fc2ee06 367 Gene3D G3DSA:3.10.150.10 1 120 7.8E-29 T 28-03-2018 MKLM6_RS05600 e390d8c2325f343d1152f384e4b89428 206 SUPERFAMILY SSF49464 111 181 3.92E-9 T 28-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain MKLM6_RS05600 e390d8c2325f343d1152f384e4b89428 206 Gene3D G3DSA:2.60.40.1120 15 192 3.7E-9 T 28-03-2018 MKLM6_RS05600 e390d8c2325f343d1152f384e4b89428 206 SUPERFAMILY SSF49503 39 129 7.75E-15 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS20535 f587a19345207df5ef37d2fee000759f 296 Gene3D G3DSA:3.90.78.10 197 291 9.8E-32 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS20535 f587a19345207df5ef37d2fee000759f 296 Gene3D G3DSA:3.30.43.10 5 78 3.9E-22 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 MKLM6_RS20535 f587a19345207df5ef37d2fee000759f 296 SUPERFAMILY SSF56176 4 187 4.67E-39 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MKLM6_RS20535 f587a19345207df5ef37d2fee000759f 296 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 296 87.012 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS20535 f587a19345207df5ef37d2fee000759f 296 SUPERFAMILY SSF56194 190 293 8.63E-36 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS20535 f587a19345207df5ef37d2fee000759f 296 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 196 290 3.3E-31 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS20535 f587a19345207df5ef37d2fee000759f 296 Pfam PF01565 FAD binding domain 33 158 7.0E-19 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MKLM6_RS20535 f587a19345207df5ef37d2fee000759f 296 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 17 290 1.2E-64 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS20535 f587a19345207df5ef37d2fee000759f 296 Gene3D G3DSA:3.30.465.10 86 196 2.8E-30 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 SUPERFAMILY SSF55785 448 574 1.74E-20 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 Gene3D G3DSA:3.30.450.20 830 942 1.4E-18 T 28-03-2018 MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 SUPERFAMILY SSF55785 573 695 8.55E-23 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 SUPERFAMILY SSF55785 192 316 2.44E-19 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 Pfam PF13188 PAS domain 337 397 6.8E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 Pfam PF08448 PAS fold 470 577 1.5E-17 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 Pfam PF08448 PAS fold 215 320 3.8E-16 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 Pfam PF08448 PAS fold 717 826 1.6E-15 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 SMART SM00086 657 699 0.2 T 28-03-2018 IPR001610 PAC motif MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 SMART SM00086 415 451 86.0 T 28-03-2018 IPR001610 PAC motif MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 SMART SM00086 534 576 26.0 T 28-03-2018 IPR001610 PAC motif MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 SMART SM00086 276 318 25.0 T 28-03-2018 IPR001610 PAC motif MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 Gene3D G3DSA:3.30.450.20 191 327 1.3E-21 T 28-03-2018 MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 Gene3D G3DSA:3.30.450.20 328 457 6.6E-22 T 28-03-2018 MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 Gene3D G3DSA:3.30.450.20 697 829 4.1E-21 T 28-03-2018 MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 SUPERFAMILY SSF55785 845 938 1.54E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 Gene3D G3DSA:3.30.450.20 577 691 6.5E-23 T 28-03-2018 MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 334 458 2.7E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 460 582 4.6E-14 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 205 320 1.9E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 850 938 4.9E-13 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 583 706 1.9E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 708 831 7.6E-12 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 SUPERFAMILY SSF55785 698 822 1.37E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 Pfam PF13426 PAS domain 597 698 8.4E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 Pfam PF13493 Domain of unknown function (DUF4118) 96 200 7.3E-21 T 28-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 SUPERFAMILY SSF55785 325 439 9.25E-13 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 Gene3D G3DSA:1.20.120.620 95 190 1.6E-19 T 28-03-2018 MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 Pfam PF00989 PAS fold 855 906 3.0E-10 T 28-03-2018 IPR013767 PAS fold GO:0006355 MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 SMART SM00091 584 648 4.8E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 SMART SM00091 463 528 0.076 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 SMART SM00091 337 404 0.0014 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 SMART SM00091 711 777 2.6 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 SMART SM00091 854 920 5.7E-12 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 SMART SM00091 204 270 3.7E-8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14190 cd160d174dbad7164be9962a8d5ac2d2 1021 Gene3D G3DSA:3.30.450.20 458 576 4.7E-27 T 28-03-2018 MKLM6_RS03970 a80f5f174c44fc2a08a0cfe17efdf6d4 477 SUPERFAMILY SSF53756 4 477 1.22E-124 T 28-03-2018 MKLM6_RS03970 a80f5f174c44fc2a08a0cfe17efdf6d4 477 Pfam PF00534 Glycosyl transferases group 1 293 439 6.3E-12 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 MKLM6_RS03970 a80f5f174c44fc2a08a0cfe17efdf6d4 477 Hamap MF_00484 Glycogen synthase [glgA]. 2 477 44.458 T 28-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 MKLM6_RS03970 a80f5f174c44fc2a08a0cfe17efdf6d4 477 Gene3D G3DSA:3.40.50.2000 17 261 7.5E-8 T 28-03-2018 MKLM6_RS03970 a80f5f174c44fc2a08a0cfe17efdf6d4 477 Pfam PF08323 Starch synthase catalytic domain 3 236 4.5E-76 T 28-03-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 MKLM6_RS03970 a80f5f174c44fc2a08a0cfe17efdf6d4 477 Gene3D G3DSA:3.40.50.2000 262 473 7.4E-40 T 28-03-2018 MKLM6_RS03970 a80f5f174c44fc2a08a0cfe17efdf6d4 477 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 3 476 3.6E-172 T 28-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 MKLM6_RS11010 bb0608062a94102a5c45ee7ada46d80b 893 Gene3D G3DSA:3.40.50.740 264 547 8.4E-78 T 28-03-2018 MKLM6_RS11010 bb0608062a94102a5c45ee7ada46d80b 893 Gene3D G3DSA:2.20.25.90 3 59 8.8E-20 T 28-03-2018 MKLM6_RS11010 bb0608062a94102a5c45ee7ada46d80b 893 Gene3D G3DSA:3.40.228.10 162 263 2.4E-23 T 28-03-2018 MKLM6_RS11010 bb0608062a94102a5c45ee7ada46d80b 893 Pfam PF00384 Molybdopterin oxidoreductase 62 486 1.6E-79 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS11010 bb0608062a94102a5c45ee7ada46d80b 893 Pfam PF01568 Molydopterin dinucleotide binding domain 590 701 1.7E-28 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 MKLM6_RS11010 bb0608062a94102a5c45ee7ada46d80b 893 Gene3D G3DSA:3.40.50.740 62 161 1.6E-17 T 28-03-2018 MKLM6_RS11010 bb0608062a94102a5c45ee7ada46d80b 893 SUPERFAMILY SSF50692 580 723 9.72E-42 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain MKLM6_RS11010 bb0608062a94102a5c45ee7ada46d80b 893 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 8 25 - T 28-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 MKLM6_RS11010 bb0608062a94102a5c45ee7ada46d80b 893 PIRSF PIRSF036643 3 728 8.1E-149 T 28-03-2018 MKLM6_RS11010 bb0608062a94102a5c45ee7ada46d80b 893 Pfam PF04324 BFD-like [2Fe-2S] binding domain 841 889 1.7E-12 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain MKLM6_RS11010 bb0608062a94102a5c45ee7ada46d80b 893 SUPERFAMILY SSF53706 4 592 1.15E-189 T 28-03-2018 MKLM6_RS11010 bb0608062a94102a5c45ee7ada46d80b 893 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 5 57 8.1E-20 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS11010 bb0608062a94102a5c45ee7ada46d80b 893 SMART SM00926 3 59 2.6E-19 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS11010 bb0608062a94102a5c45ee7ada46d80b 893 Gene3D G3DSA:2.40.40.20 548 706 1.4E-41 T 28-03-2018 MKLM6_RS10020 7c43fc9cb4d90d434602134b7a09dd7c 170 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 165 5.7E-21 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS10020 7c43fc9cb4d90d434602134b7a09dd7c 170 SUPERFAMILY SSF88946 7 94 6.28E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS10020 7c43fc9cb4d90d434602134b7a09dd7c 170 SUPERFAMILY SSF88659 106 167 9.81E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS10020 7c43fc9cb4d90d434602134b7a09dd7c 170 Pfam PF08281 Sigma-70, region 4 116 163 1.1E-14 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS10020 7c43fc9cb4d90d434602134b7a09dd7c 170 Pfam PF04542 Sigma-70 region 2 13 77 6.2E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS10020 7c43fc9cb4d90d434602134b7a09dd7c 170 Gene3D G3DSA:1.10.1740.10 5 74 9.8E-14 T 28-03-2018 MKLM6_RS10020 7c43fc9cb4d90d434602134b7a09dd7c 170 Gene3D G3DSA:1.10.10.10 75 170 2.8E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS15620 717cca158117ad2303048706b76f2a1e 1162 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 291 729 1.2E-176 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS15620 717cca158117ad2303048706b76f2a1e 1162 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 5 1032 0.0 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS15620 717cca158117ad2303048706b76f2a1e 1162 SUPERFAMILY SSF89550 5 262 5.49E-15 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MKLM6_RS15620 717cca158117ad2303048706b76f2a1e 1162 Gene3D G3DSA:1.10.150.280 781 889 1.9E-10 T 28-03-2018 MKLM6_RS15620 717cca158117ad2303048706b76f2a1e 1162 Pfam PF02811 PHP domain 7 171 7.7E-40 T 28-03-2018 IPR004013 PHP domain GO:0003824 MKLM6_RS15620 717cca158117ad2303048706b76f2a1e 1162 Gene3D G3DSA:3.20.20.140 2 247 7.6E-37 T 28-03-2018 MKLM6_RS15620 717cca158117ad2303048706b76f2a1e 1162 SMART SM00481 6 73 3.6E-22 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal MKLM6_RS15620 717cca158117ad2303048706b76f2a1e 1162 Pfam PF01336 OB-fold nucleic acid binding domain 996 1058 1.6E-6 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MKLM6_RS15620 717cca158117ad2303048706b76f2a1e 1162 Gene3D G3DSA:2.40.50.140 983 1074 3.0E-14 T 28-03-2018 MKLM6_RS15620 717cca158117ad2303048706b76f2a1e 1162 Pfam PF14579 Helix-hairpin-helix motif 804 891 2.9E-27 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 SUPERFAMILY SSF55785 669 795 3.22E-24 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 SUPERFAMILY SSF55874 890 1053 1.96E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 Pfam PF08448 PAS fold 399 507 1.1E-9 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 Pfam PF08448 PAS fold 144 251 7.2E-14 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 SMART SM00091 9 75 5.8E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 SMART SM00091 136 202 5.4 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 SMART SM00091 682 748 2.4E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 SMART SM00091 392 458 1.7E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 SMART SM00091 261 327 1.7E-13 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 SMART SM00388 835 900 2.6E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 Pfam PF00512 His Kinase A (phospho-acceptor) domain 836 900 3.9E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 Gene3D G3DSA:3.30.450.40 512 682 3.9E-26 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 Gene3D G3DSA:3.40.50.2300 1068 1197 3.0E-21 T 28-03-2018 MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 SUPERFAMILY SSF52172 1075 1193 1.17E-21 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1014 1032 3.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 PRINTS PR00344 Bacterial sensor protein C-terminal signature 979 993 3.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1038 1051 3.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 PRINTS PR00344 Bacterial sensor protein C-terminal signature 997 1007 3.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 SMART SM00065 528 678 0.0053 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 SUPERFAMILY SSF55781 529 681 2.18E-22 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 SUPERFAMILY SSF55785 20 132 4.51E-24 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 SMART SM00448 1076 1188 1.2E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 678 804 5.5E-22 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 11 132 2.3E-21 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 257 378 5.8E-22 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 135 256 3.5E-11 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 389 513 3.3E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 SMART SM00086 207 249 100.0 T 28-03-2018 IPR001610 PAC motif MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 SMART SM00086 85 125 25.0 T 28-03-2018 IPR001610 PAC motif MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 SMART SM00086 464 506 0.39 T 28-03-2018 IPR001610 PAC motif MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 SMART SM00086 334 373 1.4 T 28-03-2018 IPR001610 PAC motif MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 SMART SM00086 755 797 0.44 T 28-03-2018 IPR001610 PAC motif MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 Gene3D G3DSA:3.30.450.20 135 252 7.4E-22 T 28-03-2018 MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 SMART SM00387 944 1054 1.9E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 Gene3D G3DSA:1.10.287.130 841 896 2.4E-10 T 28-03-2018 MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 945 1053 1.7E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 SUPERFAMILY SSF55785 246 359 6.12E-26 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 Pfam PF00072 Response regulator receiver domain 1078 1188 1.2E-11 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 Pfam PF08447 PAS fold 285 356 3.3E-12 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 Pfam PF08447 PAS fold 705 788 8.7E-10 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 Pfam PF13426 PAS domain 19 123 6.7E-11 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 SUPERFAMILY SSF55785 379 503 7.85E-20 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 SUPERFAMILY SSF55785 121 241 1.93E-17 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 Gene3D G3DSA:3.30.450.20 683 840 2.5E-31 T 28-03-2018 MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 Gene3D G3DSA:3.30.450.20 7 134 2.4E-20 T 28-03-2018 MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 Pfam PF13185 GAF domain 533 668 1.5E-10 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 Gene3D G3DSA:3.30.565.10 904 1058 1.1E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 Gene3D G3DSA:3.30.450.20 253 383 2.9E-32 T 28-03-2018 MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 Gene3D G3DSA:3.30.450.20 384 511 1.2E-28 T 28-03-2018 MKLM6_RS03610 06155ec8d5819e67a71e21cb5e4a07d7 1197 SUPERFAMILY SSF47384 820 900 3.14E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS13805 a683c14f06ab47424360bd96b0b31a6f 284 PRINTS PR00721 Stomatin signature 25 47 1.3E-8 T 28-03-2018 IPR001972 Stomatin family GO:0016020 MKLM6_RS13805 a683c14f06ab47424360bd96b0b31a6f 284 PRINTS PR00721 Stomatin signature 73 94 1.3E-8 T 28-03-2018 IPR001972 Stomatin family GO:0016020 MKLM6_RS13805 a683c14f06ab47424360bd96b0b31a6f 284 PRINTS PR00721 Stomatin signature 176 197 1.3E-8 T 28-03-2018 IPR001972 Stomatin family GO:0016020 MKLM6_RS13805 a683c14f06ab47424360bd96b0b31a6f 284 PRINTS PR00721 Stomatin signature 157 175 1.3E-8 T 28-03-2018 IPR001972 Stomatin family GO:0016020 MKLM6_RS13805 a683c14f06ab47424360bd96b0b31a6f 284 TIGRFAM TIGR01932 hflC: HflC protein 145 280 2.3E-45 T 28-03-2018 IPR010200 HflC GO:0016021|GO:0052547 MKLM6_RS13805 a683c14f06ab47424360bd96b0b31a6f 284 SMART SM00244 18 181 2.0E-34 T 28-03-2018 IPR001107 Band 7 domain MKLM6_RS13805 a683c14f06ab47424360bd96b0b31a6f 284 PIRSF PIRSF005651 2 284 9.1E-91 T 28-03-2018 IPR010200 HflC GO:0016021|GO:0052547 MKLM6_RS13805 a683c14f06ab47424360bd96b0b31a6f 284 SUPERFAMILY SSF117892 50 187 6.54E-30 T 28-03-2018 IPR001107 Band 7 domain MKLM6_RS13805 a683c14f06ab47424360bd96b0b31a6f 284 Pfam PF01145 SPFH domain / Band 7 family 22 196 1.4E-27 T 28-03-2018 IPR001107 Band 7 domain MKLM6_RS14735 450b26c556223199ee258215c4066e8c 233 ProDom PD102047 MEMBRANE SUBUNIT OUTER RECEPTOR IMPORT TRANSLOCASE MITOCHONDRIAL TRANSMEMBRANE MITOCHONDRION DIRECT 53 144 0.002 T 28-03-2018 MKLM6_RS14735 450b26c556223199ee258215c4066e8c 233 Pfam PF06552 Plant specific mitochondrial import receptor subunit TOM20 53 144 7.8E-6 T 28-03-2018 MKLM6_RS14735 450b26c556223199ee258215c4066e8c 233 Gene3D G3DSA:3.30.70.100 4 87 0.006 T 28-03-2018 MKLM6_RS14735 450b26c556223199ee258215c4066e8c 233 SUPERFAMILY SSF48452 34 163 1.64E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS14735 450b26c556223199ee258215c4066e8c 233 Gene3D G3DSA:1.25.40.10 118 199 6.5E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS20820 5cd099bba9f2c0c88b745d88cc52a948 186 Pfam PF01584 CheW-like domain 23 165 4.9E-36 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS20820 5cd099bba9f2c0c88b745d88cc52a948 186 SUPERFAMILY SSF50341 20 168 1.7E-36 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS20820 5cd099bba9f2c0c88b745d88cc52a948 186 Gene3D G3DSA:2.40.50.180 42 102 5.4E-20 T 28-03-2018 MKLM6_RS20820 5cd099bba9f2c0c88b745d88cc52a948 186 SMART SM00260 19 164 2.7E-33 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS20820 5cd099bba9f2c0c88b745d88cc52a948 186 Gene3D G3DSA:2.30.30.40 103 158 3.4E-21 T 28-03-2018 MKLM6_RS11925 cbf4a517f0aa1430f2fe36f824c50884 434 Gene3D G3DSA:2.40.160.20 320 432 1.1E-5 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MKLM6_RS11925 cbf4a517f0aa1430f2fe36f824c50884 434 Gene3D G3DSA:2.40.160.20 93 189 0.072 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MKLM6_RS11925 cbf4a517f0aa1430f2fe36f824c50884 434 SUPERFAMILY SSF56935 127 281 5.95E-10 T 28-03-2018 MKLM6_RS11925 cbf4a517f0aa1430f2fe36f824c50884 434 SUPERFAMILY SSF56935 309 401 5.95E-10 T 28-03-2018 MKLM6_RS11925 cbf4a517f0aa1430f2fe36f824c50884 434 Gene3D G3DSA:2.40.170.20 190 319 1.6E-8 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS03990 c6c9616c80fe71739dd4532bc0505773 490 SUPERFAMILY SSF51445 7 489 7.82E-160 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily MKLM6_RS03990 c6c9616c80fe71739dd4532bc0505773 490 Gene3D G3DSA:3.20.20.80 4 490 3.8E-160 T 28-03-2018 MKLM6_RS03990 c6c9616c80fe71739dd4532bc0505773 490 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 4 490 3.6E-107 T 28-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 MKLM6_RS03990 c6c9616c80fe71739dd4532bc0505773 490 Pfam PF02446 4-alpha-glucanotransferase 14 469 2.4E-150 T 28-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 MKLM6_RS20200 98f0161b9d3ebccdb89412c663f15014 308 Gene3D G3DSA:2.40.30.30 180 308 1.2E-37 T 28-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 MKLM6_RS20200 98f0161b9d3ebccdb89412c663f15014 308 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 18 307 5.0E-100 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MKLM6_RS20200 98f0161b9d3ebccdb89412c663f15014 308 PIRSF PIRSF004491 1 308 8.7E-104 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MKLM6_RS20200 98f0161b9d3ebccdb89412c663f15014 308 SUPERFAMILY SSF52374 16 175 1.1E-30 T 28-03-2018 MKLM6_RS20200 98f0161b9d3ebccdb89412c663f15014 308 SUPERFAMILY SSF82114 174 308 2.62E-44 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 MKLM6_RS20200 98f0161b9d3ebccdb89412c663f15014 308 SMART SM00904 183 308 9.3E-60 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 MKLM6_RS20200 98f0161b9d3ebccdb89412c663f15014 308 Gene3D G3DSA:3.40.50.620 1 179 1.9E-43 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS20200 98f0161b9d3ebccdb89412c663f15014 308 Pfam PF01687 Riboflavin kinase 184 307 1.2E-36 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 MKLM6_RS20200 98f0161b9d3ebccdb89412c663f15014 308 Pfam PF06574 FAD synthetase 14 166 2.1E-49 T 28-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MKLM6_RS08695 dce0bc6e0054fba0b4e812231379901e 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 251 272 3.4E-119 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08695 dce0bc6e0054fba0b4e812231379901e 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 200 219 3.4E-119 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08695 dce0bc6e0054fba0b4e812231379901e 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 99 123 3.4E-119 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08695 dce0bc6e0054fba0b4e812231379901e 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 321 342 3.4E-119 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08695 dce0bc6e0054fba0b4e812231379901e 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 356 374 3.4E-119 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08695 dce0bc6e0054fba0b4e812231379901e 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 171 189 3.4E-119 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08695 dce0bc6e0054fba0b4e812231379901e 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 434 455 3.4E-119 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08695 dce0bc6e0054fba0b4e812231379901e 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 25 50 3.4E-119 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08695 dce0bc6e0054fba0b4e812231379901e 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 72 95 3.4E-119 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08695 dce0bc6e0054fba0b4e812231379901e 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 142 154 3.4E-119 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08695 dce0bc6e0054fba0b4e812231379901e 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 384 403 3.4E-119 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08695 dce0bc6e0054fba0b4e812231379901e 538 PRINTS PR01165 Cytochrome c oxidase subunit I signature 297 312 3.4E-119 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08695 dce0bc6e0054fba0b4e812231379901e 538 Gene3D G3DSA:1.20.210.10 22 533 4.3E-217 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08695 dce0bc6e0054fba0b4e812231379901e 538 SUPERFAMILY SSF81442 22 531 1.02E-190 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08695 dce0bc6e0054fba0b4e812231379901e 538 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 253 307 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08695 dce0bc6e0054fba0b4e812231379901e 538 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 34 476 1.7E-147 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08695 dce0bc6e0054fba0b4e812231379901e 538 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 26 531 8.0E-206 T 28-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 MKLM6_RS01225 bb93e866419c694f5e23bb8d20b9f068 188 Pfam PF01618 MotA/TolQ/ExbB proton channel family 66 145 3.0E-10 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 MKLM6_RS13535 3ef6d7e94861bec03c8d0db432f35b67 612 Gene3D G3DSA:1.10.150.20 552 610 3.0E-12 T 28-03-2018 MKLM6_RS13535 3ef6d7e94861bec03c8d0db432f35b67 612 SUPERFAMILY SSF47781 518 608 6.04E-20 T 28-03-2018 IPR010994 RuvA domain 2-like MKLM6_RS13535 3ef6d7e94861bec03c8d0db432f35b67 612 Pfam PF01541 GIY-YIG catalytic domain 23 97 6.0E-11 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily MKLM6_RS13535 3ef6d7e94861bec03c8d0db432f35b67 612 Gene3D G3DSA:4.10.860.10 186 247 1.3E-13 T 28-03-2018 IPR001943 UVR domain GO:0005515 MKLM6_RS13535 3ef6d7e94861bec03c8d0db432f35b67 612 Gene3D G3DSA:3.40.1440.10 9 105 4.3E-22 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily MKLM6_RS13535 3ef6d7e94861bec03c8d0db432f35b67 612 Hamap MF_00203 UvrABC system protein C [uvrC]. 8 605 27.861 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 MKLM6_RS13535 3ef6d7e94861bec03c8d0db432f35b67 612 Pfam PF14520 Helix-hairpin-helix domain 556 603 3.7E-6 T 28-03-2018 MKLM6_RS13535 3ef6d7e94861bec03c8d0db432f35b67 612 SUPERFAMILY SSF82771 21 104 2.09E-21 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily MKLM6_RS13535 3ef6d7e94861bec03c8d0db432f35b67 612 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 385 540 1.2E-49 T 28-03-2018 IPR001162 UvrC family homology region MKLM6_RS13535 3ef6d7e94861bec03c8d0db432f35b67 612 SUPERFAMILY SSF46600 195 247 6.93E-13 T 28-03-2018 IPR001943 UVR domain GO:0005515 MKLM6_RS13535 3ef6d7e94861bec03c8d0db432f35b67 612 Pfam PF02151 UvrB/uvrC motif 210 242 2.7E-8 T 28-03-2018 IPR001943 UVR domain GO:0005515 MKLM6_RS13535 3ef6d7e94861bec03c8d0db432f35b67 612 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 13 586 1.5E-187 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 MKLM6_RS13535 3ef6d7e94861bec03c8d0db432f35b67 612 SMART SM00465 21 102 5.9E-21 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily MKLM6_RS17455 dcfb15a9968a0da52edb99ce5c0598ed 300 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 7 297 3.8E-35 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MKLM6_RS17455 dcfb15a9968a0da52edb99ce5c0598ed 300 Gene3D G3DSA:3.30.70.1350 219 299 5.1E-10 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain MKLM6_RS17455 dcfb15a9968a0da52edb99ce5c0598ed 300 Pfam PF01545 Cation efflux family 11 215 2.1E-31 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MKLM6_RS17455 dcfb15a9968a0da52edb99ce5c0598ed 300 Gene3D G3DSA:1.20.1510.10 5 218 2.8E-29 T 28-03-2018 MKLM6_RS17455 dcfb15a9968a0da52edb99ce5c0598ed 300 Pfam PF16916 Dimerisation domain of Zinc Transporter 222 294 5.1E-7 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain MKLM6_RS17455 dcfb15a9968a0da52edb99ce5c0598ed 300 SUPERFAMILY SSF161111 4 219 7.19E-34 T 28-03-2018 MKLM6_RS17455 dcfb15a9968a0da52edb99ce5c0598ed 300 SUPERFAMILY SSF160240 221 297 2.49E-8 T 28-03-2018 MKLM6_RS08655 2c7ed4086500b3bf796427dc0e3b54e7 233 SUPERFAMILY SSF53271 61 231 6.69E-32 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like MKLM6_RS08655 2c7ed4086500b3bf796427dc0e3b54e7 233 Pfam PF00156 Phosphoribosyl transferase domain 142 229 2.0E-6 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MKLM6_RS08655 2c7ed4086500b3bf796427dc0e3b54e7 233 Gene3D G3DSA:3.40.50.2020 56 233 1.9E-25 T 28-03-2018 MKLM6_RS20680 4237dca6813ab3f205ebeb7ab096e92c 220 Pfam PF00005 ABC transporter 21 169 1.0E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS20680 4237dca6813ab3f205ebeb7ab096e92c 220 SMART SM00382 30 217 1.9E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS20680 4237dca6813ab3f205ebeb7ab096e92c 220 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS20680 4237dca6813ab3f205ebeb7ab096e92c 220 Gene3D G3DSA:3.40.50.300 1 220 9.5E-61 T 28-03-2018 MKLM6_RS20680 4237dca6813ab3f205ebeb7ab096e92c 220 SUPERFAMILY SSF52540 1 218 2.9E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 SUPERFAMILY SSF47336 1749 1819 2.73E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 SUPERFAMILY SSF52151 541 674 2.28E-66 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 SUPERFAMILY SSF52151 734 830 2.28E-66 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 Gene3D G3DSA:1.10.1200.10 1737 1830 1.5E-19 T 28-03-2018 MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1162 1360 7.2E-46 T 28-03-2018 MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 SUPERFAMILY SSF55048 672 730 2.09E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 278 396 2.1E-40 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 Pfam PF08659 KR domain 1162 1359 1.2E-44 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 Gene3D G3DSA:3.40.47.10 1 282 6.3E-68 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 Gene3D G3DSA:3.40.366.10 541 680 2.5E-40 T 28-03-2018 MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 SMART SM00823 Phosphopantetheine attachment site 1755 1823 3.6E-6 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 Gene3D G3DSA:3.40.50.720 1154 1404 1.5E-36 T 28-03-2018 MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 SMART SM00826 1385 1549 4.2E-4 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 10 270 7.9E-65 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 Gene3D G3DSA:3.40.366.10 727 850 3.2E-25 T 28-03-2018 MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 Pfam PF00698 Acyl transferase domain 542 840 3.3E-48 T 28-03-2018 IPR014043 Acyl transferase MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 Gene3D G3DSA:3.30.70.250 681 726 3.2E-16 T 28-03-2018 MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 SMART SM00825 Beta-ketoacyl synthase 11 448 6.4E-165 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 SUPERFAMILY SSF53901 423 444 8.18E-78 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 SUPERFAMILY SSF53901 5 134 8.18E-78 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 SUPERFAMILY SSF53901 165 392 8.18E-78 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 399 508 8.0E-15 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 Gene3D G3DSA:3.40.50.10090 935 1099 0.012 T 28-03-2018 MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 Gene3D G3DSA:3.10.129.10 1405 1508 5.3E-8 T 28-03-2018 MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 Pfam PF14765 Polyketide synthase dehydratase 1385 1670 1.8E-35 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 SUPERFAMILY SSF51735 914 1147 2.5E-13 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 SUPERFAMILY SSF51735 1162 1366 2.5E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 182 198 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 Pfam PF00550 Phosphopantetheine attachment site 1758 1819 8.1E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1779 1794 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 544 842 1.5E-99 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 Gene3D G3DSA:3.40.47.10 286 446 1.1E-54 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS12285 8c1795c90bdbdeff298d7046498a3c0f 2211 SMART SM01294 1756 1819 1.3E-4 T 28-03-2018 MKLM6_RS19125 2ce2bc72f4dcfa232ec154e4c8b3b0ec 277 Pfam PF01464 Transglycosylase SLT domain 145 246 1.4E-29 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 MKLM6_RS19125 2ce2bc72f4dcfa232ec154e4c8b3b0ec 277 Pfam PF08238 Sel1 repeat 33 57 0.018 T 28-03-2018 IPR006597 Sel1-like repeat MKLM6_RS19125 2ce2bc72f4dcfa232ec154e4c8b3b0ec 277 Pfam PF08238 Sel1 repeat 58 93 6.8E-6 T 28-03-2018 IPR006597 Sel1-like repeat MKLM6_RS19125 2ce2bc72f4dcfa232ec154e4c8b3b0ec 277 SMART SM00671 23 57 0.15 T 28-03-2018 IPR006597 Sel1-like repeat MKLM6_RS19125 2ce2bc72f4dcfa232ec154e4c8b3b0ec 277 SMART SM00671 58 93 4.4E-9 T 28-03-2018 IPR006597 Sel1-like repeat MKLM6_RS19125 2ce2bc72f4dcfa232ec154e4c8b3b0ec 277 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 157 185 - T 28-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 MKLM6_RS19125 2ce2bc72f4dcfa232ec154e4c8b3b0ec 277 SUPERFAMILY SSF53955 133 257 7.88E-45 T 28-03-2018 IPR023346 Lysozyme-like domain MKLM6_RS19125 2ce2bc72f4dcfa232ec154e4c8b3b0ec 277 SUPERFAMILY SSF81901 33 101 2.88E-16 T 28-03-2018 MKLM6_RS19125 2ce2bc72f4dcfa232ec154e4c8b3b0ec 277 Gene3D G3DSA:2.60.40.1180 9 79 2.6E-15 T 28-03-2018 MKLM6_RS19125 2ce2bc72f4dcfa232ec154e4c8b3b0ec 277 Gene3D G3DSA:2.60.40.1180 80 104 0.0042 T 28-03-2018 MKLM6_RS19125 2ce2bc72f4dcfa232ec154e4c8b3b0ec 277 Gene3D G3DSA:1.10.530.10 121 269 1.9E-39 T 28-03-2018 MKLM6_RS01625 a1bba7547797094cf3eda38322269848 173 TIGRFAM TIGR02667 moaB_proteo: molybdenum cofactor biosynthesis protein B 6 168 1.5E-80 T 28-03-2018 IPR013484 Molybdenum cofactor biosynthesis protein B, proteobacteria GO:0006777 MKLM6_RS01625 a1bba7547797094cf3eda38322269848 173 PIRSF PIRSF006443 1 165 1.9E-61 T 28-03-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 MKLM6_RS01625 a1bba7547797094cf3eda38322269848 173 Pfam PF00994 Probable molybdopterin binding domain 13 154 1.2E-31 T 28-03-2018 IPR001453 MoaB/Mog domain MKLM6_RS01625 a1bba7547797094cf3eda38322269848 173 Gene3D G3DSA:3.40.980.10 1 168 4.4E-33 T 28-03-2018 IPR001453 MoaB/Mog domain MKLM6_RS01625 a1bba7547797094cf3eda38322269848 173 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 10 151 5.0E-34 T 28-03-2018 IPR001453 MoaB/Mog domain MKLM6_RS01625 a1bba7547797094cf3eda38322269848 173 SUPERFAMILY SSF53218 4 168 2.22E-45 T 28-03-2018 IPR001453 MoaB/Mog domain MKLM6_RS01625 a1bba7547797094cf3eda38322269848 173 SMART SM00852 13 157 2.6E-28 T 28-03-2018 IPR001453 MoaB/Mog domain MKLM6_RS15370 fb9cbb8d9042653bd2977da196772440 287 TIGRFAM TIGR03006 pepcterm_polyde: polysaccharide deacetylase family protein, PEP-CTERM locus subfamily 9 279 9.1E-137 T 28-03-2018 IPR014344 PEP-CTERM locus, polysaccharide deactylase MKLM6_RS15370 fb9cbb8d9042653bd2977da196772440 287 SUPERFAMILY SSF88713 12 257 4.17E-47 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MKLM6_RS15370 fb9cbb8d9042653bd2977da196772440 287 Pfam PF11959 Domain of unknown function (DUF3473) 151 279 2.4E-51 T 28-03-2018 IPR022560 Domain of unknown function DUF3473 MKLM6_RS15370 fb9cbb8d9042653bd2977da196772440 287 Pfam PF01522 Polysaccharide deacetylase 37 148 1.2E-20 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MKLM6_RS15370 fb9cbb8d9042653bd2977da196772440 287 Gene3D G3DSA:3.20.20.370 33 281 5.8E-43 T 28-03-2018 MKLM6_RS14355 76f8b01add347d77f14058eaa7cb77a7 131 SUPERFAMILY SSF54631 3 128 6.32E-32 T 28-03-2018 MKLM6_RS14355 76f8b01add347d77f14058eaa7cb77a7 131 Gene3D G3DSA:3.10.580.10 1 131 1.5E-29 T 28-03-2018 MKLM6_RS14355 76f8b01add347d77f14058eaa7cb77a7 131 SMART SM00116 14 62 4.3E-7 T 28-03-2018 IPR000644 CBS domain MKLM6_RS14355 76f8b01add347d77f14058eaa7cb77a7 131 SMART SM00116 81 128 3.0E-6 T 28-03-2018 IPR000644 CBS domain MKLM6_RS14355 76f8b01add347d77f14058eaa7cb77a7 131 Pfam PF00571 CBS domain 7 55 2.5E-12 T 28-03-2018 IPR000644 CBS domain MKLM6_RS14355 76f8b01add347d77f14058eaa7cb77a7 131 Pfam PF00571 CBS domain 74 128 4.6E-11 T 28-03-2018 IPR000644 CBS domain MKLM6_RS01320 53e4ad8af713235085c17c021d8be9b7 763 Gene3D G3DSA:3.20.20.210 2 392 1.9E-151 T 28-03-2018 MKLM6_RS01320 53e4ad8af713235085c17c021d8be9b7 763 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 4 318 7.3E-115 T 28-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MKLM6_RS01320 53e4ad8af713235085c17c021d8be9b7 763 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 2 761 37.409 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MKLM6_RS01320 53e4ad8af713235085c17c021d8be9b7 763 SUPERFAMILY SSF51726 5 397 1.57E-110 T 28-03-2018 MKLM6_RS01320 53e4ad8af713235085c17c021d8be9b7 763 Gene3D G3DSA:3.20.20.210 393 762 2.3E-129 T 28-03-2018 MKLM6_RS01320 53e4ad8af713235085c17c021d8be9b7 763 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 434 756 4.9E-154 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MKLM6_RS01320 53e4ad8af713235085c17c021d8be9b7 763 SUPERFAMILY SSF51726 399 759 8.5E-118 T 28-03-2018 MKLM6_RS01320 53e4ad8af713235085c17c021d8be9b7 763 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 7 760 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MKLM6_RS01320 53e4ad8af713235085c17c021d8be9b7 763 PIRSF PIRSF000382 1 763 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MKLM6_RS21020 0a515b692c0584e84010950df886a71e 171 Pfam PF04542 Sigma-70 region 2 8 73 1.4E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS21020 0a515b692c0584e84010950df886a71e 171 Pfam PF08281 Sigma-70, region 4 104 156 1.1E-16 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS21020 0a515b692c0584e84010950df886a71e 171 SUPERFAMILY SSF88659 96 160 2.83E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS21020 0a515b692c0584e84010950df886a71e 171 Gene3D G3DSA:1.10.10.10 71 163 5.9E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS21020 0a515b692c0584e84010950df886a71e 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 160 4.2E-21 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS21020 0a515b692c0584e84010950df886a71e 171 SUPERFAMILY SSF88946 6 89 3.02E-12 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS21020 0a515b692c0584e84010950df886a71e 171 Gene3D G3DSA:1.10.1740.10 3 70 1.2E-13 T 28-03-2018 MKLM6_RS05615 40d371557ab849b7294b13e2ae7507bb 243 SMART SM00862 159 235 4.8E-30 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS05615 40d371557ab849b7294b13e2ae7507bb 243 SUPERFAMILY SSF46894 136 236 1.43E-31 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MKLM6_RS05615 40d371557ab849b7294b13e2ae7507bb 243 Gene3D G3DSA:1.10.10.10 133 242 3.7E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS05615 40d371557ab849b7294b13e2ae7507bb 243 Gene3D G3DSA:3.40.50.2300 1 132 1.6E-35 T 28-03-2018 MKLM6_RS05615 40d371557ab849b7294b13e2ae7507bb 243 SMART SM00448 5 119 1.2E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS05615 40d371557ab849b7294b13e2ae7507bb 243 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 235 4.3E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS05615 40d371557ab849b7294b13e2ae7507bb 243 Pfam PF00072 Response regulator receiver domain 8 119 3.4E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS05615 40d371557ab849b7294b13e2ae7507bb 243 SUPERFAMILY SSF52172 3 132 1.85E-38 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS03290 68eb81b026269f439b0bb75822332297 554 PIRSF PIRSF006453 1 550 1.1E-235 T 28-03-2018 IPR012027 Formylmethanofuran dehydrogenase, subunit A MKLM6_RS03290 68eb81b026269f439b0bb75822332297 554 Gene3D G3DSA:2.30.40.10 399 490 4.6E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MKLM6_RS03290 68eb81b026269f439b0bb75822332297 554 TIGRFAM TIGR03121 one_C_dehyd_A: formylmethanofuran dehydrogenase subunit A 3 539 1.3E-235 T 28-03-2018 IPR012027 Formylmethanofuran dehydrogenase, subunit A MKLM6_RS03290 68eb81b026269f439b0bb75822332297 554 Pfam PF07969 Amidohydrolase family 43 493 5.8E-57 T 28-03-2018 IPR013108 Amidohydrolase 3 MKLM6_RS03290 68eb81b026269f439b0bb75822332297 554 SUPERFAMILY SSF51338 450 494 6.96E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MKLM6_RS03290 68eb81b026269f439b0bb75822332297 554 SUPERFAMILY SSF51338 4 54 6.96E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MKLM6_RS03290 68eb81b026269f439b0bb75822332297 554 Gene3D G3DSA:3.20.20.140 59 323 8.7E-9 T 28-03-2018 MKLM6_RS03290 68eb81b026269f439b0bb75822332297 554 Gene3D G3DSA:2.30.40.10 2 58 1.8E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MKLM6_RS03290 68eb81b026269f439b0bb75822332297 554 SUPERFAMILY SSF51556 55 450 8.16E-27 T 28-03-2018 IPR032466 Metal-dependent hydrolase MKLM6_RS21315 d057e91643a9216900bcc90daf78176a 319 Pfam PF16344 Domain of unknown function (DUF4974) 218 306 1.6E-8 T 28-03-2018 IPR032508 Protein FecR, C-terminal MKLM6_RS21315 d057e91643a9216900bcc90daf78176a 319 Pfam PF16220 Domain of unknown function (DUF4880) 10 51 1.7E-12 T 28-03-2018 IPR032623 FecR, N-terminal MKLM6_RS21315 d057e91643a9216900bcc90daf78176a 319 Pfam PF04773 FecR protein 110 201 1.1E-21 T 28-03-2018 IPR006860 FecR protein MKLM6_RS21315 d057e91643a9216900bcc90daf78176a 319 PIRSF PIRSF018266 1 319 1.3E-91 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component MKLM6_RS15150 7bc33a2804cf3bb57f234c84691af4e7 193 TIGRFAM TIGR01943 rnfA: electron transport complex, RnfABCDGE type, A subunit 3 190 1.4E-84 T 28-03-2018 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 MKLM6_RS15150 7bc33a2804cf3bb57f234c84691af4e7 193 PIRSF PIRSF006102 1 193 1.3E-59 T 28-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 MKLM6_RS15150 7bc33a2804cf3bb57f234c84691af4e7 193 Pfam PF02508 Rnf-Nqr subunit, membrane protein 5 190 4.0E-59 T 28-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 MKLM6_RS15150 7bc33a2804cf3bb57f234c84691af4e7 193 Hamap MF_00459 Electron transport complex subunit RsxA [rsxA]. 2 191 25.881 T 28-03-2018 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 MKLM6_RS20490 d66431640216ce01493847e0a9d62468 90 Hamap MF_00910 Cell division protein FtsL [ftsL]. 5 88 14.554 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 MKLM6_RS20490 d66431640216ce01493847e0a9d62468 90 Pfam PF04999 Cell division protein FtsL 5 89 2.3E-19 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 MKLM6_RS20490 d66431640216ce01493847e0a9d62468 90 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 6 88 1.6E-19 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 MKLM6_RS06535 4c618951acbc53f45362f4b722b18420 180 SUPERFAMILY SSF55729 13 162 3.49E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS06535 4c618951acbc53f45362f4b722b18420 180 Pfam PF00583 Acetyltransferase (GNAT) family 63 130 5.6E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 MKLM6_RS06535 4c618951acbc53f45362f4b722b18420 180 Gene3D G3DSA:3.40.630.30 17 166 2.3E-27 T 28-03-2018 MKLM6_RS06535 4c618951acbc53f45362f4b722b18420 180 TIGRFAM TIGR04045 MSMEG_0567_GNAT: putative N-acetyltransferase, MSMEG_0567 N-terminal domain family 13 164 6.4E-72 T 28-03-2018 IPR024035 GNAT N-acetyltransferase, putative MKLM6_RS15905 70fbfb22e9257ff50ac4d7f36738d5c3 645 SUPERFAMILY SSF110942 523 640 9.15E-36 T 28-03-2018 MKLM6_RS15905 70fbfb22e9257ff50ac4d7f36738d5c3 645 SUPERFAMILY SSF54211 241 496 1.59E-99 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS15905 70fbfb22e9257ff50ac4d7f36738d5c3 645 SUPERFAMILY SSF55874 8 216 6.81E-66 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS15905 70fbfb22e9257ff50ac4d7f36738d5c3 645 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 30 185 1.8E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS15905 70fbfb22e9257ff50ac4d7f36738d5c3 645 Pfam PF00183 Hsp90 protein 229 642 6.1E-142 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 MKLM6_RS15905 70fbfb22e9257ff50ac4d7f36738d5c3 645 Hamap MF_00505 Chaperone protein HtpG [htpG]. 5 641 32.987 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 MKLM6_RS15905 70fbfb22e9257ff50ac4d7f36738d5c3 645 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 28 37 - T 28-03-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 MKLM6_RS15905 70fbfb22e9257ff50ac4d7f36738d5c3 645 PIRSF PIRSF002583 2 645 2.2E-225 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 MKLM6_RS15905 70fbfb22e9257ff50ac4d7f36738d5c3 645 PRINTS PR00775 90kDa heat shock protein signature 96 113 4.2E-61 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MKLM6_RS15905 70fbfb22e9257ff50ac4d7f36738d5c3 645 PRINTS PR00775 90kDa heat shock protein signature 175 192 4.2E-61 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MKLM6_RS15905 70fbfb22e9257ff50ac4d7f36738d5c3 645 PRINTS PR00775 90kDa heat shock protein signature 193 211 4.2E-61 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MKLM6_RS15905 70fbfb22e9257ff50ac4d7f36738d5c3 645 PRINTS PR00775 90kDa heat shock protein signature 78 95 4.2E-61 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MKLM6_RS15905 70fbfb22e9257ff50ac4d7f36738d5c3 645 PRINTS PR00775 90kDa heat shock protein signature 123 145 4.2E-61 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MKLM6_RS15905 70fbfb22e9257ff50ac4d7f36738d5c3 645 PRINTS PR00775 90kDa heat shock protein signature 29 51 4.2E-61 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MKLM6_RS15905 70fbfb22e9257ff50ac4d7f36738d5c3 645 PRINTS PR00775 90kDa heat shock protein signature 8 28 4.2E-61 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MKLM6_RS15905 70fbfb22e9257ff50ac4d7f36738d5c3 645 SMART SM00387 30 187 5.6E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS15905 70fbfb22e9257ff50ac4d7f36738d5c3 645 Gene3D G3DSA:3.30.565.10 32 225 2.1E-53 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SUPERFAMILY SSF55785 22 130 2.09E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 Pfam PF00563 EAL domain 1255 1490 1.4E-76 T 28-03-2018 IPR001633 EAL domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SUPERFAMILY SSF55785 269 376 2.9E-17 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SUPERFAMILY SSF55785 770 899 1.92E-19 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 Pfam PF13426 PAS domain 674 772 2.2E-8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SUPERFAMILY SSF141868 1255 1499 2.22E-91 T 28-03-2018 IPR001633 EAL domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 Pfam PF08448 PAS fold 791 903 3.0E-9 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 Pfam PF08448 PAS fold 549 656 2.0E-13 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 Gene3D G3DSA:3.30.450.20 664 776 4.0E-24 T 28-03-2018 MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 Gene3D G3DSA:3.30.450.20 139 264 1.6E-21 T 28-03-2018 MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 Gene3D G3DSA:3.30.450.40 903 1073 1.7E-14 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 Gene3D G3DSA:3.30.450.40 379 537 3.3E-15 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 Gene3D G3DSA:3.30.450.20 777 902 3.5E-22 T 28-03-2018 MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SUPERFAMILY SSF55785 651 770 4.33E-22 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 Gene3D G3DSA:3.20.20.450 1240 1498 6.9E-104 T 28-03-2018 IPR001633 EAL domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 Gene3D G3DSA:3.30.450.20 267 378 2.1E-19 T 28-03-2018 MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 1074 1236 9.3E-47 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 Pfam PF00989 PAS fold 137 234 1.5E-6 T 28-03-2018 IPR013767 PAS fold GO:0006355 MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SUPERFAMILY SSF55781 923 1078 1.09E-14 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SMART SM00091 662 728 4.4E-6 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SMART SM00091 136 202 1.1E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SMART SM00091 9 81 0.57 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SMART SM00091 541 607 3.1E-4 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SMART SM00091 258 326 220.0 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SMART SM00091 785 853 2.0E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SMART SM00086 733 773 140.0 T 28-03-2018 IPR001610 PAC motif MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SMART SM00086 87 128 0.025 T 28-03-2018 IPR001610 PAC motif MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SMART SM00086 859 901 2.1 T 28-03-2018 IPR001610 PAC motif MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SMART SM00086 206 246 130.0 T 28-03-2018 IPR001610 PAC motif MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SMART SM00086 332 374 1.1E-7 T 28-03-2018 IPR001610 PAC motif MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 Pfam PF00990 Diguanylate cyclase, GGDEF domain 1078 1234 3.1E-52 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 Gene3D G3DSA:3.30.450.20 538 663 8.8E-25 T 28-03-2018 MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 30 135 2.1E-6 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 781 900 2.7E-6 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 659 780 8.9E-19 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 133 253 1.8E-17 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 537 661 3.9E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 307 381 4.2E-6 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 Pfam PF08447 PAS fold 281 367 1.3E-16 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 Pfam PF08447 PAS fold 37 113 2.1E-13 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SUPERFAMILY SSF55785 147 254 3.77E-20 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 Gene3D G3DSA:3.30.70.270 1074 1239 1.4E-64 T 28-03-2018 MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SUPERFAMILY SSF55781 394 539 7.2E-13 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 Gene3D G3DSA:3.30.450.20 4 138 2.0E-20 T 28-03-2018 MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SMART SM00267 1067 1239 4.8E-69 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SMART SM00052 1249 1495 4.1E-114 T 28-03-2018 IPR001633 EAL domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SMART SM00065 923 1075 0.54 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SMART SM00065 392 537 0.0037 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SUPERFAMILY SSF55785 528 652 3.07E-20 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11425 c33a39801ab3cdf97a3f9829e44f78ee 1501 SUPERFAMILY SSF55073 1083 1240 5.89E-52 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS19285 927abee4ce43d31fe7409cb81ce36915 292 SUPERFAMILY SSF53850 91 288 6.21E-25 T 28-03-2018 MKLM6_RS19285 927abee4ce43d31fe7409cb81ce36915 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.6E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS19285 927abee4ce43d31fe7409cb81ce36915 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.6E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS19285 927abee4ce43d31fe7409cb81ce36915 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.6E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS19285 927abee4ce43d31fe7409cb81ce36915 292 Gene3D G3DSA:3.40.190.10 95 178 4.9E-8 T 28-03-2018 MKLM6_RS19285 927abee4ce43d31fe7409cb81ce36915 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 1.9E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS19285 927abee4ce43d31fe7409cb81ce36915 292 SUPERFAMILY SSF46785 3 85 8.18E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS19285 927abee4ce43d31fe7409cb81ce36915 292 Pfam PF03466 LysR substrate binding domain 90 288 2.0E-22 T 28-03-2018 IPR005119 LysR, substrate-binding MKLM6_RS19285 927abee4ce43d31fe7409cb81ce36915 292 Gene3D G3DSA:3.40.190.10 179 264 1.4E-10 T 28-03-2018 MKLM6_RS19285 927abee4ce43d31fe7409cb81ce36915 292 Gene3D G3DSA:1.10.10.10 1 85 1.8E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS07115 8974d8373da7643aa0b99f2f5a570705 252 SUPERFAMILY SSF48452 35 202 3.41E-25 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS07115 8974d8373da7643aa0b99f2f5a570705 252 TIGRFAM TIGR02521 type_IV_pilW: type IV pilus biogenesis/stability protein PilW 9 238 7.8E-63 T 28-03-2018 IPR013360 Pilus biogenesis/stability type IV, PilW MKLM6_RS07115 8974d8373da7643aa0b99f2f5a570705 252 Gene3D G3DSA:1.25.40.10 177 251 3.2E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS07115 8974d8373da7643aa0b99f2f5a570705 252 Pfam PF13432 Tetratricopeptide repeat 40 102 6.2E-5 T 28-03-2018 MKLM6_RS07115 8974d8373da7643aa0b99f2f5a570705 252 Gene3D G3DSA:1.25.40.10 123 176 1.3E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS07115 8974d8373da7643aa0b99f2f5a570705 252 Pfam PF13424 Tetratricopeptide repeat 104 169 2.2E-9 T 28-03-2018 MKLM6_RS07115 8974d8373da7643aa0b99f2f5a570705 252 Gene3D G3DSA:1.25.40.10 80 122 2.3E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS07115 8974d8373da7643aa0b99f2f5a570705 252 SMART SM00028 103 136 200.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS07115 8974d8373da7643aa0b99f2f5a570705 252 SMART SM00028 69 102 0.012 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS07115 8974d8373da7643aa0b99f2f5a570705 252 SMART SM00028 139 172 4.0E-6 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS07115 8974d8373da7643aa0b99f2f5a570705 252 SMART SM00028 35 68 84.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS07115 8974d8373da7643aa0b99f2f5a570705 252 Gene3D G3DSA:1.25.40.10 31 79 2.5E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS02870 116d967ce96388ed1fe77981dceda8a8 303 SUPERFAMILY SSF56281 1 303 3.11E-62 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS02870 116d967ce96388ed1fe77981dceda8a8 303 Pfam PF12706 Beta-lactamase superfamily domain 50 270 1.2E-46 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS02870 116d967ce96388ed1fe77981dceda8a8 303 TIGRFAM TIGR02108 PQQ_syn_pqqB: coenzyme PQQ biosynthesis protein B 2 303 3.0E-131 T 28-03-2018 IPR011842 Coenzyme PQQ biosynthesis protein B GO:0006810|GO:0018189 MKLM6_RS02870 116d967ce96388ed1fe77981dceda8a8 303 Gene3D G3DSA:3.60.15.10 1 303 1.8E-41 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS02870 116d967ce96388ed1fe77981dceda8a8 303 Hamap MF_00653 Coenzyme PQQ synthesis protein B [pqqB]. 1 303 159.659 T 28-03-2018 IPR011842 Coenzyme PQQ biosynthesis protein B GO:0006810|GO:0018189 MKLM6_RS18615 cb1b165370c8c62852e84acff9182a1b 611 SMART SM00052 346 591 9.1E-85 T 28-03-2018 IPR001633 EAL domain MKLM6_RS18615 cb1b165370c8c62852e84acff9182a1b 611 SUPERFAMILY SSF141868 353 586 2.09E-76 T 28-03-2018 IPR001633 EAL domain MKLM6_RS18615 cb1b165370c8c62852e84acff9182a1b 611 Gene3D G3DSA:3.20.20.450 339 589 2.4E-80 T 28-03-2018 IPR001633 EAL domain MKLM6_RS18615 cb1b165370c8c62852e84acff9182a1b 611 Pfam PF00990 Diguanylate cyclase, GGDEF domain 172 329 1.2E-30 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS18615 cb1b165370c8c62852e84acff9182a1b 611 Pfam PF00563 EAL domain 354 586 2.1E-69 T 28-03-2018 IPR001633 EAL domain MKLM6_RS18615 cb1b165370c8c62852e84acff9182a1b 611 SUPERFAMILY SSF55073 176 336 1.26E-35 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS18615 cb1b165370c8c62852e84acff9182a1b 611 SMART SM00267 160 334 2.6E-31 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS18615 cb1b165370c8c62852e84acff9182a1b 611 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 168 333 1.8E-27 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS18615 cb1b165370c8c62852e84acff9182a1b 611 Gene3D G3DSA:3.30.70.270 164 338 5.3E-40 T 28-03-2018 MKLM6_RS18615 cb1b165370c8c62852e84acff9182a1b 611 SUPERFAMILY SSF52172 12 173 1.42E-7 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS18615 cb1b165370c8c62852e84acff9182a1b 611 Gene3D G3DSA:3.40.50.2300 7 154 4.3E-7 T 28-03-2018 MKLM6_RS12745 1e34c3ee0179e28b966d18d311db6467 309 Gene3D G3DSA:3.40.50.150 101 283 6.0E-33 T 28-03-2018 MKLM6_RS12745 1e34c3ee0179e28b966d18d311db6467 309 Pfam PF05175 Methyltransferase small domain 134 212 2.5E-15 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 MKLM6_RS12745 1e34c3ee0179e28b966d18d311db6467 309 SUPERFAMILY SSF53335 15 294 1.42E-49 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS12745 1e34c3ee0179e28b966d18d311db6467 309 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 204 210 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MKLM6_RS12745 1e34c3ee0179e28b966d18d311db6467 309 Gene3D G3DSA:1.10.8.10 14 100 5.3E-12 T 28-03-2018 MKLM6_RS12745 1e34c3ee0179e28b966d18d311db6467 309 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 12 294 3.1E-120 T 28-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 MKLM6_RS12745 1e34c3ee0179e28b966d18d311db6467 309 Hamap MF_02125 50S ribosomal protein L3 glutamine methyltransferase [prmB]. 5 300 48.883 T 28-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 MKLM6_RS12745 1e34c3ee0179e28b966d18d311db6467 309 PIRSF PIRSF037167 2 307 3.2E-128 T 28-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 MKLM6_RS12745 1e34c3ee0179e28b966d18d311db6467 309 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 14 304 2.2E-72 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 MKLM6_RS15570 7999afa275fb3b075823cd260fdc6563 240 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 31 209 2.9E-47 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 MKLM6_RS15570 7999afa275fb3b075823cd260fdc6563 240 Gene3D G3DSA:3.40.50.620 2 240 1.6E-45 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS15570 7999afa275fb3b075823cd260fdc6563 240 PIRSF PIRSF000857 1 239 2.6E-81 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 MKLM6_RS15570 7999afa275fb3b075823cd260fdc6563 240 SUPERFAMILY SSF52402 5 197 1.61E-48 T 28-03-2018 MKLM6_RS15570 7999afa275fb3b075823cd260fdc6563 240 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 20 234 1.6E-53 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 MKLM6_RS15570 7999afa275fb3b075823cd260fdc6563 240 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 38 233 2.4E-81 T 28-03-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 MKLM6_RS13280 6b2e015948438faca5efa98e7676e338 64 Pfam PF04400 (Na+)-NQR maturation NqrM 22 56 4.0E-5 T 28-03-2018 IPR007495 (Na+)-NQR maturation factor NqrM MKLM6_RS20055 c7a4aba641c47e9373d40867d85ecab8 169 Gene3D G3DSA:1.25.40.20 18 120 4.2E-29 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain MKLM6_RS20055 c7a4aba641c47e9373d40867d85ecab8 169 Gene3D G3DSA:1.25.40.20 121 160 8.0E-5 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain MKLM6_RS20055 c7a4aba641c47e9373d40867d85ecab8 169 SMART SM00248 54 83 8.8E-5 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 MKLM6_RS20055 c7a4aba641c47e9373d40867d85ecab8 169 SMART SM00248 87 116 0.022 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 MKLM6_RS20055 c7a4aba641c47e9373d40867d85ecab8 169 Pfam PF12796 Ankyrin repeats (3 copies) 27 118 8.7E-15 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain MKLM6_RS20055 c7a4aba641c47e9373d40867d85ecab8 169 SUPERFAMILY SSF48403 25 151 3.42E-30 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain MKLM6_RS01020 f144c7d3c1b6026cd81275784a873669 363 Hamap MF_02040 Iron-sulfur cluster carrier protein. 93 341 37.961 T 28-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein MKLM6_RS01020 f144c7d3c1b6026cd81275784a873669 363 Pfam PF01883 Iron-sulfur cluster assembly protein 6 78 2.2E-16 T 28-03-2018 IPR002744 MIP18 family-like MKLM6_RS01020 f144c7d3c1b6026cd81275784a873669 363 SUPERFAMILY SSF52540 100 344 1.38E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS01020 f144c7d3c1b6026cd81275784a873669 363 ProSitePatterns PS01215 Mrp family signature. 204 220 - T 28-03-2018 IPR000808 Mrp, conserved site GO:0005524 MKLM6_RS01020 f144c7d3c1b6026cd81275784a873669 363 SUPERFAMILY SSF117916 5 86 4.9E-15 T 28-03-2018 IPR034904 Fe-S cluster assembly domain MKLM6_RS01020 f144c7d3c1b6026cd81275784a873669 363 Gene3D G3DSA:3.30.300.130 2 91 1.1E-13 T 28-03-2018 IPR034904 Fe-S cluster assembly domain MKLM6_RS01020 f144c7d3c1b6026cd81275784a873669 363 Gene3D G3DSA:3.40.50.300 92 319 4.1E-64 T 28-03-2018 MKLM6_RS01020 f144c7d3c1b6026cd81275784a873669 363 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 97 340 7.3E-103 T 28-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 MKLM6_RS11535 93cc757c002a3d9001c4428680f02e0b 69 ProDom PD056452 UNCHARACTERIZED BACTERIA SIMILAR YPEB CYTOPLASMIC VCA0163 PRODUCT STM2426 GENE YPO2988 14 69 1.0E-22 T 28-03-2018 IPR024530 Putative quorum-sensing-regulated virulence factor MKLM6_RS11535 93cc757c002a3d9001c4428680f02e0b 69 Pfam PF12843 Putative quorum-sensing-regulated virulence factor 2 67 2.8E-31 T 28-03-2018 IPR024530 Putative quorum-sensing-regulated virulence factor MKLM6_RS01915 19bb33328fe9e7fb616c8f1ac74ec2de 628 SMART SM00382 337 504 5.4E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS01915 19bb33328fe9e7fb616c8f1ac74ec2de 628 SMART SM00382 26 223 1.2E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS01915 19bb33328fe9e7fb616c8f1ac74ec2de 628 Gene3D G3DSA:3.40.50.300 2 279 1.1E-54 T 28-03-2018 MKLM6_RS01915 19bb33328fe9e7fb616c8f1ac74ec2de 628 Pfam PF12848 ABC transporter 217 293 2.6E-29 T 28-03-2018 IPR032781 ABC-transporter extension domain MKLM6_RS01915 19bb33328fe9e7fb616c8f1ac74ec2de 628 SUPERFAMILY SSF52540 294 513 1.52E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS01915 19bb33328fe9e7fb616c8f1ac74ec2de 628 Pfam PF00005 ABC transporter 328 459 9.4E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS01915 19bb33328fe9e7fb616c8f1ac74ec2de 628 Pfam PF00005 ABC transporter 19 178 4.8E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS01915 19bb33328fe9e7fb616c8f1ac74ec2de 628 Gene3D G3DSA:3.40.50.300 308 618 7.8E-53 T 28-03-2018 MKLM6_RS01915 19bb33328fe9e7fb616c8f1ac74ec2de 628 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS01915 19bb33328fe9e7fb616c8f1ac74ec2de 628 ProSitePatterns PS00211 ABC transporters family signature. 431 445 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS01915 19bb33328fe9e7fb616c8f1ac74ec2de 628 SUPERFAMILY SSF52540 119 256 1.31E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS01915 19bb33328fe9e7fb616c8f1ac74ec2de 628 SUPERFAMILY SSF52540 2 92 1.31E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS22530 736ab00e378c1689dc65219f060aa44e 175 Gene3D G3DSA:2.10.109.10 23 175 1.1E-14 T 28-03-2018 MKLM6_RS22530 736ab00e378c1689dc65219f060aa44e 175 SUPERFAMILY SSF51306 55 173 1.15E-19 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MKLM6_RS22530 736ab00e378c1689dc65219f060aa44e 175 Pfam PF10502 Signal peptidase, peptidase S26 53 171 1.1E-13 T 28-03-2018 IPR019533 Peptidase S26 MKLM6_RS02690 93bc0ea123113e6c489a3fa085feaceb 221 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 111 138 0.0013 T 28-03-2018 MKLM6_RS06660 e4d20e7e251efdd780c7e9f4888df476 303 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 131 243 2.7E-30 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 MKLM6_RS06660 e4d20e7e251efdd780c7e9f4888df476 303 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 11 288 18.104 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 MKLM6_RS06660 e4d20e7e251efdd780c7e9f4888df476 303 Pfam PF01867 CRISPR associated protein Cas1 128 228 4.3E-10 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 MKLM6_RS06660 e4d20e7e251efdd780c7e9f4888df476 303 TIGRFAM TIGR03638 cas1_ECOLI: CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI 7 271 2.0E-115 T 28-03-2018 IPR019851 CRISPR-associated protein Cas1, ECOLI subtype GO:0004520|GO:0043571|GO:0046872 MKLM6_RS17470 53e9af871c7ce94a07d648b436d66466 590 Gene3D G3DSA:3.90.780.10 385 587 8.0E-47 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MKLM6_RS17470 53e9af871c7ce94a07d648b436d66466 590 Pfam PF02872 5'-nucleotidase, C-terminal domain 371 551 1.3E-33 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MKLM6_RS17470 53e9af871c7ce94a07d648b436d66466 590 SUPERFAMILY SSF55816 369 587 7.46E-43 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MKLM6_RS17470 53e9af871c7ce94a07d648b436d66466 590 Pfam PF00149 Calcineurin-like phosphoesterase 29 290 9.9E-8 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MKLM6_RS17470 53e9af871c7ce94a07d648b436d66466 590 Gene3D G3DSA:3.60.21.10 18 384 3.7E-73 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS17470 53e9af871c7ce94a07d648b436d66466 590 SUPERFAMILY SSF56300 25 369 7.6E-68 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS17470 53e9af871c7ce94a07d648b436d66466 590 PRINTS PR01607 Apyrase family signature 273 296 5.5E-21 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MKLM6_RS17470 53e9af871c7ce94a07d648b436d66466 590 PRINTS PR01607 Apyrase family signature 438 461 5.5E-21 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MKLM6_RS17470 53e9af871c7ce94a07d648b436d66466 590 PRINTS PR01607 Apyrase family signature 304 324 5.5E-21 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MKLM6_RS17470 53e9af871c7ce94a07d648b436d66466 590 PRINTS PR01607 Apyrase family signature 525 544 5.5E-21 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MKLM6_RS17470 53e9af871c7ce94a07d648b436d66466 590 PRINTS PR01607 Apyrase family signature 27 45 5.5E-21 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 SMART SM00086 183 225 2.1E-8 T 28-03-2018 IPR001610 PAC motif MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 SMART SM00086 305 347 9.7E-7 T 28-03-2018 IPR001610 PAC motif MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 SMART SM00086 60 99 1.3 T 28-03-2018 IPR001610 PAC motif MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 354 519 3.1E-49 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 107 232 8.6E-14 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 237 354 1.6E-21 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 Gene3D G3DSA:3.30.450.20 97 231 1.3E-35 T 28-03-2018 MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 SMART SM00267 347 520 7.0E-73 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 Gene3D G3DSA:3.40.50.10600 232 351 3.9E-28 T 28-03-2018 MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 SUPERFAMILY SSF55073 363 522 2.28E-53 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 SMART SM00052 530 776 2.3E-114 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 Pfam PF13188 PAS domain 387 429 0.1 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 Pfam PF00990 Diguanylate cyclase, GGDEF domain 358 516 5.9E-54 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 Pfam PF00989 PAS fold 7 41 1.6E-5 T 28-03-2018 IPR013767 PAS fold GO:0006355 MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 Gene3D G3DSA:3.20.20.450 528 790 2.6E-98 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 SUPERFAMILY SSF55785 238 345 4.89E-31 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 SMART SM00091 233 299 5.7E-8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 SMART SM00091 6 71 3.1E-4 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 SMART SM00091 111 177 0.016 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 SUPERFAMILY SSF55785 17 108 9.77E-12 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 Gene3D G3DSA:3.30.70.270 352 527 3.4E-64 T 28-03-2018 MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 SUPERFAMILY SSF141868 537 784 8.63E-88 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 Pfam PF13426 PAS domain 244 346 1.1E-17 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 Gene3D G3DSA:3.30.450.20 3 96 3.8E-14 T 28-03-2018 MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 Pfam PF08447 PAS fold 135 219 4.9E-15 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 SUPERFAMILY SSF55785 96 223 5.93E-25 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14720 920b4f11d30ad85c3bccecce23314bef 793 Pfam PF00563 EAL domain 537 771 1.4E-74 T 28-03-2018 IPR001633 EAL domain MKLM6_RS08390 36e38c04e2b10b04ccc88f6228a1bbb0 400 SUPERFAMILY SSF51735 150 336 4.56E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS08390 36e38c04e2b10b04ccc88f6228a1bbb0 400 Hamap MF_03210 Formate dehydrogenase, mitochondrial. 2 383 56.211 T 28-03-2018 IPR033689 NAD-dependent formate dehydrogenase GO:0008863 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 MKLM6_RS08390 36e38c04e2b10b04ccc88f6228a1bbb0 400 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 157 335 2.1E-51 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MKLM6_RS08390 36e38c04e2b10b04ccc88f6228a1bbb0 400 Gene3D G3DSA:3.40.50.720 2 174 7.1E-42 T 28-03-2018 MKLM6_RS08390 36e38c04e2b10b04ccc88f6228a1bbb0 400 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 61 361 1.2E-17 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 MKLM6_RS08390 36e38c04e2b10b04ccc88f6228a1bbb0 400 SUPERFAMILY SSF52283 3 177 2.55E-61 T 28-03-2018 MKLM6_RS08390 36e38c04e2b10b04ccc88f6228a1bbb0 400 Gene3D G3DSA:3.40.50.720 175 336 6.2E-40 T 28-03-2018 MKLM6_RS07715 b7cb56a652c344aa44a30c0a6c0f9df2 224 Pfam PF01066 CDP-alcohol phosphatidyltransferase 34 107 9.1E-7 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MKLM6_RS11030 c8a453dbcbe4cfbcf2f20951fef322d3 337 SUPERFAMILY SSF161098 124 325 2.22E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MKLM6_RS11030 c8a453dbcbe4cfbcf2f20951fef322d3 337 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 148 331 1.4E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MKLM6_RS11030 c8a453dbcbe4cfbcf2f20951fef322d3 337 Gene3D G3DSA:1.10.3720.10 33 337 1.4E-24 T 28-03-2018 MKLM6_RS13360 a580d1ab31b82f407a0f7f6cd0a18ec1 1297 Pfam PF04408 Helicase associated domain (HA2) 470 555 8.0E-18 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 MKLM6_RS13360 a580d1ab31b82f407a0f7f6cd0a18ec1 1297 SUPERFAMILY SSF52540 78 586 8.86E-102 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS13360 a580d1ab31b82f407a0f7f6cd0a18ec1 1297 SMART SM00490 308 406 1.2E-14 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS13360 a580d1ab31b82f407a0f7f6cd0a18ec1 1297 Pfam PF00271 Helicase conserved C-terminal domain 287 405 8.8E-12 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS13360 a580d1ab31b82f407a0f7f6cd0a18ec1 1297 SMART SM00487 73 257 4.8E-23 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MKLM6_RS13360 a580d1ab31b82f407a0f7f6cd0a18ec1 1297 SMART SM00382 90 388 7.3E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS13360 a580d1ab31b82f407a0f7f6cd0a18ec1 1297 SMART SM00847 466 556 4.3E-31 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 MKLM6_RS13360 a580d1ab31b82f407a0f7f6cd0a18ec1 1297 Pfam PF11898 Domain of unknown function (DUF3418) 711 1294 3.3E-185 T 28-03-2018 IPR024590 RNA helicase HrpA, C-terminal MKLM6_RS13360 a580d1ab31b82f407a0f7f6cd0a18ec1 1297 Gene3D G3DSA:3.40.50.300 251 426 3.1E-46 T 28-03-2018 MKLM6_RS13360 a580d1ab31b82f407a0f7f6cd0a18ec1 1297 Gene3D G3DSA:3.40.50.300 74 233 1.2E-27 T 28-03-2018 MKLM6_RS13360 a580d1ab31b82f407a0f7f6cd0a18ec1 1297 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 11 1294 0.0 T 28-03-2018 IPR010222 RNA helicase HrpA GO:0004004 MKLM6_RS13360 a580d1ab31b82f407a0f7f6cd0a18ec1 1297 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 620 695 1.2E-13 T 28-03-2018 IPR011709 Domain of unknown function DUF1605 MKLM6_RS06515 bed20f988870c5403122cdf4ac341e93 446 Gene3D G3DSA:1.20.1250.20 1 222 3.8E-23 T 28-03-2018 MKLM6_RS06515 bed20f988870c5403122cdf4ac341e93 446 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 164 176 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 MKLM6_RS06515 bed20f988870c5403122cdf4ac341e93 446 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 93 117 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 MKLM6_RS06515 bed20f988870c5403122cdf4ac341e93 446 Pfam PF00854 POT family 237 412 1.9E-28 T 28-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 MKLM6_RS06515 bed20f988870c5403122cdf4ac341e93 446 Pfam PF00854 POT family 106 215 5.3E-29 T 28-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 MKLM6_RS06515 bed20f988870c5403122cdf4ac341e93 446 Gene3D G3DSA:1.20.1250.20 237 445 9.6E-12 T 28-03-2018 MKLM6_RS06515 bed20f988870c5403122cdf4ac341e93 446 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 4 243 8.0E-58 T 28-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 MKLM6_RS06515 bed20f988870c5403122cdf4ac341e93 446 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 232 441 1.5E-41 T 28-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 MKLM6_RS06515 bed20f988870c5403122cdf4ac341e93 446 SUPERFAMILY SSF103473 75 441 3.92E-34 T 28-03-2018 IPR020846 Major facilitator superfamily domain MKLM6_RS06515 bed20f988870c5403122cdf4ac341e93 446 SUPERFAMILY SSF103473 6 47 3.92E-34 T 28-03-2018 IPR020846 Major facilitator superfamily domain MKLM6_RS13240 ed20f1ec3b52f6e521b7c38ee748f599 254 Pfam PF00557 Metallopeptidase family M24 12 241 1.4E-54 T 28-03-2018 IPR000994 Peptidase M24 MKLM6_RS13240 ed20f1ec3b52f6e521b7c38ee748f599 254 SUPERFAMILY SSF55920 3 252 1.44E-93 T 28-03-2018 IPR000994 Peptidase M24 MKLM6_RS13240 ed20f1ec3b52f6e521b7c38ee748f599 254 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 249 2.0E-103 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MKLM6_RS13240 ed20f1ec3b52f6e521b7c38ee748f599 254 Gene3D G3DSA:3.90.230.10 2 254 4.7E-90 T 28-03-2018 MKLM6_RS13240 ed20f1ec3b52f6e521b7c38ee748f599 254 PRINTS PR00599 Methionine aminopeptidase-1 signature 161 173 2.6E-23 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MKLM6_RS13240 ed20f1ec3b52f6e521b7c38ee748f599 254 PRINTS PR00599 Methionine aminopeptidase-1 signature 69 82 2.6E-23 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MKLM6_RS13240 ed20f1ec3b52f6e521b7c38ee748f599 254 PRINTS PR00599 Methionine aminopeptidase-1 signature 91 107 2.6E-23 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MKLM6_RS13240 ed20f1ec3b52f6e521b7c38ee748f599 254 PRINTS PR00599 Methionine aminopeptidase-1 signature 192 204 2.6E-23 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MKLM6_RS13240 ed20f1ec3b52f6e521b7c38ee748f599 254 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 167 185 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MKLM6_RS13240 ed20f1ec3b52f6e521b7c38ee748f599 254 Hamap MF_01974 Methionine aminopeptidase [map]. 3 250 43.134 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MKLM6_RS20035 f24f36fa376fe413caa31e1b5fb7f52f 259 PIRSF PIRSF001356 1 259 3.9E-138 T 28-03-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 MKLM6_RS20035 f24f36fa376fe413caa31e1b5fb7f52f 259 Pfam PF02675 S-adenosylmethionine decarboxylase 37 167 1.1E-32 T 28-03-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 MKLM6_RS20035 f24f36fa376fe413caa31e1b5fb7f52f 259 Gene3D G3DSA:3.60.90.10 31 187 2.2E-46 T 28-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 MKLM6_RS20035 f24f36fa376fe413caa31e1b5fb7f52f 259 Hamap MF_00465 S-adenosylmethionine decarboxylase proenzyme [speD]. 1 259 154.314 T 28-03-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 MKLM6_RS20035 f24f36fa376fe413caa31e1b5fb7f52f 259 TIGRFAM TIGR03331 SAM_DCase_Eco: S-adenosylmethionine decarboxylase proenzyme 3 258 5.8E-140 T 28-03-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 MKLM6_RS20035 f24f36fa376fe413caa31e1b5fb7f52f 259 SUPERFAMILY SSF56276 110 171 4.32E-24 T 28-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 MKLM6_RS20035 f24f36fa376fe413caa31e1b5fb7f52f 259 SUPERFAMILY SSF56276 42 83 4.32E-24 T 28-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 MKLM6_RS15225 0adcf305dea5844a8ee0e2f164b88d26 343 Pfam PF07589 PEP-CTERM motif 312 335 7.6E-7 T 28-03-2018 IPR013424 PEP-CTERM protein-sorting domain MKLM6_RS15225 0adcf305dea5844a8ee0e2f164b88d26 343 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 313 336 2.7E-4 T 28-03-2018 IPR013424 PEP-CTERM protein-sorting domain MKLM6_RS17845 2b386b51bdd0333e3cde16f3ca61c4a5 587 SMART SM00671 143 174 8.8E-4 T 28-03-2018 IPR006597 Sel1-like repeat MKLM6_RS17845 2b386b51bdd0333e3cde16f3ca61c4a5 587 SMART SM00671 175 210 6.0E-5 T 28-03-2018 IPR006597 Sel1-like repeat MKLM6_RS17845 2b386b51bdd0333e3cde16f3ca61c4a5 587 SUPERFAMILY SSF52129 314 540 6.63E-17 T 28-03-2018 IPR029030 Caspase-like domain MKLM6_RS17845 2b386b51bdd0333e3cde16f3ca61c4a5 587 Gene3D G3DSA:3.40.50.1460 319 570 3.7E-35 T 28-03-2018 MKLM6_RS17845 2b386b51bdd0333e3cde16f3ca61c4a5 587 Gene3D G3DSA:1.25.40.10 102 216 3.2E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS17845 2b386b51bdd0333e3cde16f3ca61c4a5 587 SUPERFAMILY SSF81901 125 207 1.83E-17 T 28-03-2018 MKLM6_RS17845 2b386b51bdd0333e3cde16f3ca61c4a5 587 Gene3D G3DSA:1.20.5.50 217 312 4.3E-4 T 28-03-2018 MKLM6_RS17845 2b386b51bdd0333e3cde16f3ca61c4a5 587 Pfam PF00656 Caspase domain 326 525 3.0E-20 T 28-03-2018 MKLM6_RS17845 2b386b51bdd0333e3cde16f3ca61c4a5 587 Pfam PF08238 Sel1 repeat 146 174 0.061 T 28-03-2018 IPR006597 Sel1-like repeat MKLM6_RS17845 2b386b51bdd0333e3cde16f3ca61c4a5 587 Pfam PF08238 Sel1 repeat 175 206 1.1E-4 T 28-03-2018 IPR006597 Sel1-like repeat MKLM6_RS10655 f8e7da126af90e0ae39e304fe2bd6a75 302 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 MKLM6_RS10655 f8e7da126af90e0ae39e304fe2bd6a75 302 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 301 1.1E-135 T 28-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MKLM6_RS10655 f8e7da126af90e0ae39e304fe2bd6a75 302 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 7 292 3.7E-72 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MKLM6_RS10655 f8e7da126af90e0ae39e304fe2bd6a75 302 Gene3D G3DSA:3.40.50.1100 41 139 5.8E-37 T 28-03-2018 MKLM6_RS10655 f8e7da126af90e0ae39e304fe2bd6a75 302 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 301 1.7E-129 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MKLM6_RS10655 f8e7da126af90e0ae39e304fe2bd6a75 302 SUPERFAMILY SSF53686 2 301 5.89E-103 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MKLM6_RS10655 f8e7da126af90e0ae39e304fe2bd6a75 302 Gene3D G3DSA:3.40.50.1100 140 302 2.6E-58 T 28-03-2018 MKLM6_RS19500 2e9a4c800551415a4c0634a7ab4412f7 235 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 6 118 1.8E-22 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MKLM6_RS19500 2e9a4c800551415a4c0634a7ab4412f7 235 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 4 123 18.949 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MKLM6_RS19500 2e9a4c800551415a4c0634a7ab4412f7 235 TIGRFAM TIGR00494 crcB: protein CrcB 6 120 1.6E-27 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MKLM6_RS00040 dfc282dc3743aa3dba6f5c789fd4d22b 354 Pfam PF13533 Biotin-lipoyl like 47 93 5.9E-9 T 28-03-2018 MKLM6_RS00040 dfc282dc3743aa3dba6f5c789fd4d22b 354 SUPERFAMILY SSF111369 40 108 1.7E-6 T 28-03-2018 MKLM6_RS00040 dfc282dc3743aa3dba6f5c789fd4d22b 354 Gene3D G3DSA:2.40.50.100 206 334 0.013 T 28-03-2018 MKLM6_RS00040 dfc282dc3743aa3dba6f5c789fd4d22b 354 Gene3D G3DSA:1.10.287.470 116 192 1.2E-9 T 28-03-2018 MKLM6_RS00040 dfc282dc3743aa3dba6f5c789fd4d22b 354 Gene3D G3DSA:2.40.50.100 47 115 8.2E-11 T 28-03-2018 MKLM6_RS00040 dfc282dc3743aa3dba6f5c789fd4d22b 354 SUPERFAMILY SSF111369 189 260 1.09E-8 T 28-03-2018 MKLM6_RS00040 dfc282dc3743aa3dba6f5c789fd4d22b 354 SUPERFAMILY SSF111369 115 153 1.09E-8 T 28-03-2018 MKLM6_RS00040 dfc282dc3743aa3dba6f5c789fd4d22b 354 Pfam PF13437 HlyD family secretion protein 213 321 7.7E-13 T 28-03-2018 MKLM6_RS13935 797455d893120a44e49f75097da80027 242 Gene3D G3DSA:3.40.50.720 3 166 2.8E-34 T 28-03-2018 MKLM6_RS13935 797455d893120a44e49f75097da80027 242 Gene3D G3DSA:3.40.50.720 167 241 8.2E-10 T 28-03-2018 MKLM6_RS13935 797455d893120a44e49f75097da80027 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MKLM6_RS13935 797455d893120a44e49f75097da80027 242 SUPERFAMILY SSF51735 1 236 1.86E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS13935 797455d893120a44e49f75097da80027 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.3E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS13935 797455d893120a44e49f75097da80027 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.3E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS13935 797455d893120a44e49f75097da80027 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.3E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS13935 797455d893120a44e49f75097da80027 242 Pfam PF00106 short chain dehydrogenase 7 202 7.5E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS15420 465b6338b9e19cb932cb956206a6c7de 695 SUPERFAMILY SSF55781 318 468 6.87E-10 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS15420 465b6338b9e19cb932cb956206a6c7de 695 PRINTS PR00344 Bacterial sensor protein C-terminal signature 634 644 8.2E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS15420 465b6338b9e19cb932cb956206a6c7de 695 PRINTS PR00344 Bacterial sensor protein C-terminal signature 615 629 8.2E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS15420 465b6338b9e19cb932cb956206a6c7de 695 PRINTS PR00344 Bacterial sensor protein C-terminal signature 646 664 8.2E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS15420 465b6338b9e19cb932cb956206a6c7de 695 PRINTS PR00344 Bacterial sensor protein C-terminal signature 670 683 8.2E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS15420 465b6338b9e19cb932cb956206a6c7de 695 SUPERFAMILY SSF55874 556 685 1.96E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS15420 465b6338b9e19cb932cb956206a6c7de 695 Gene3D G3DSA:3.30.565.10 527 687 1.2E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS15420 465b6338b9e19cb932cb956206a6c7de 695 SMART SM00387 577 686 1.2E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS15420 465b6338b9e19cb932cb956206a6c7de 695 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 578 685 1.3E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS15420 465b6338b9e19cb932cb956206a6c7de 695 Gene3D G3DSA:3.30.450.40 304 473 8.1E-9 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS15420 465b6338b9e19cb932cb956206a6c7de 695 TIGRFAM TIGR02916 PEP_his_kin: putative PEP-CTERM system histidine kinase 8 683 2.8E-198 T 28-03-2018 IPR014265 Signal transduction histidine kinase, PEP-CTERM system, putative MKLM6_RS04570 b5ed79d4eb8dc8d26b7d2b20fcd495c8 384 SUPERFAMILY SSF55073 212 356 3.06E-39 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS04570 b5ed79d4eb8dc8d26b7d2b20fcd495c8 384 SMART SM00267 196 364 2.2E-47 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS04570 b5ed79d4eb8dc8d26b7d2b20fcd495c8 384 Pfam PF11563 Protoglobin 18 171 8.8E-29 T 28-03-2018 MKLM6_RS04570 b5ed79d4eb8dc8d26b7d2b20fcd495c8 384 Gene3D G3DSA:1.10.490.10 2 174 1.5E-34 T 28-03-2018 MKLM6_RS04570 b5ed79d4eb8dc8d26b7d2b20fcd495c8 384 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 204 357 1.7E-37 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS04570 b5ed79d4eb8dc8d26b7d2b20fcd495c8 384 Pfam PF00990 Diguanylate cyclase, GGDEF domain 209 357 2.2E-36 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS04570 b5ed79d4eb8dc8d26b7d2b20fcd495c8 384 SUPERFAMILY SSF46458 6 167 1.13E-28 T 28-03-2018 IPR009050 Globin-like MKLM6_RS04570 b5ed79d4eb8dc8d26b7d2b20fcd495c8 384 Gene3D G3DSA:3.30.70.270 197 360 1.2E-43 T 28-03-2018 MKLM6_RS18290 80fbd27daf820d4148fbb8b01b29b661 541 PRINTS PR00315 GTP-binding elongation factor signature 124 135 1.8E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18290 80fbd27daf820d4148fbb8b01b29b661 541 PRINTS PR00315 GTP-binding elongation factor signature 108 118 1.8E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18290 80fbd27daf820d4148fbb8b01b29b661 541 PRINTS PR00315 GTP-binding elongation factor signature 88 96 1.8E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18290 80fbd27daf820d4148fbb8b01b29b661 541 PRINTS PR00315 GTP-binding elongation factor signature 26 39 1.8E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18290 80fbd27daf820d4148fbb8b01b29b661 541 PRINTS PR00315 GTP-binding elongation factor signature 161 170 1.8E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18290 80fbd27daf820d4148fbb8b01b29b661 541 Pfam PF00009 Elongation factor Tu GTP binding domain 23 211 2.0E-44 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18290 80fbd27daf820d4148fbb8b01b29b661 541 SUPERFAMILY SSF50447 242 323 2.65E-23 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain MKLM6_RS18290 80fbd27daf820d4148fbb8b01b29b661 541 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 25 432 3.6E-198 T 28-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MKLM6_RS18290 80fbd27daf820d4148fbb8b01b29b661 541 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 81 96 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site MKLM6_RS18290 80fbd27daf820d4148fbb8b01b29b661 541 Gene3D G3DSA:2.40.30.10 235 325 4.7E-22 T 28-03-2018 MKLM6_RS18290 80fbd27daf820d4148fbb8b01b29b661 541 Hamap MF_00062 Sulfate adenylyltransferase subunit 1 [cysN]. 16 493 53.115 T 28-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MKLM6_RS18290 80fbd27daf820d4148fbb8b01b29b661 541 SUPERFAMILY SSF52540 18 233 3.41E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS18290 80fbd27daf820d4148fbb8b01b29b661 541 Gene3D G3DSA:3.40.50.300 1 234 2.7E-42 T 28-03-2018 MKLM6_RS18290 80fbd27daf820d4148fbb8b01b29b661 541 SUPERFAMILY SSF50465 331 433 1.15E-35 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MKLM6_RS18290 80fbd27daf820d4148fbb8b01b29b661 541 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 31 210 1.9E-13 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MKLM6_RS18290 80fbd27daf820d4148fbb8b01b29b661 541 Gene3D G3DSA:2.40.30.10 329 434 2.6E-29 T 28-03-2018 MKLM6_RS12045 70e91e70d0759cbb7219381c5a8bb914 214 Gene3D G3DSA:3.30.450.30 87 195 4.0E-4 T 28-03-2018 MKLM6_RS12045 70e91e70d0759cbb7219381c5a8bb914 214 SUPERFAMILY SSF103196 88 151 5.75E-7 T 28-03-2018 MKLM6_RS02700 df360febeb8fc09e7eaf1594ce1dece5 358 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 4 357 1.8E-180 T 28-03-2018 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 MKLM6_RS02700 df360febeb8fc09e7eaf1594ce1dece5 358 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 171 182 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MKLM6_RS02700 df360febeb8fc09e7eaf1594ce1dece5 358 PIRSF PIRSF001359 13 358 4.0E-97 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MKLM6_RS02700 df360febeb8fc09e7eaf1594ce1dece5 358 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 14 357 5.9E-112 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MKLM6_RS02700 df360febeb8fc09e7eaf1594ce1dece5 358 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 100 111 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MKLM6_RS02700 df360febeb8fc09e7eaf1594ce1dece5 358 SUPERFAMILY SSF51569 4 357 6.59E-130 T 28-03-2018 MKLM6_RS02700 df360febeb8fc09e7eaf1594ce1dece5 358 Pfam PF01116 Fructose-bisphosphate aldolase class-II 17 356 2.6E-88 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MKLM6_RS02700 df360febeb8fc09e7eaf1594ce1dece5 358 Gene3D G3DSA:3.20.20.70 4 358 2.4E-101 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS05705 e83da977eb605c4679950101748e6f99 1021 Gene3D G3DSA:1.25.40.10 864 940 3.9E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS05705 e83da977eb605c4679950101748e6f99 1021 Gene3D G3DSA:1.25.40.10 941 1018 3.1E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS05705 e83da977eb605c4679950101748e6f99 1021 Pfam PF12969 Domain of Unknown Function with PDB structure (DUF3857) 54 221 2.2E-11 T 28-03-2018 IPR024618 Domain of unknown function DUF3857 MKLM6_RS05705 e83da977eb605c4679950101748e6f99 1021 Pfam PF01841 Transglutaminase-like superfamily 273 345 6.4E-5 T 28-03-2018 IPR002931 Transglutaminase-like MKLM6_RS05705 e83da977eb605c4679950101748e6f99 1021 Gene3D G3DSA:1.25.40.10 682 863 3.2E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS05705 e83da977eb605c4679950101748e6f99 1021 SUPERFAMILY SSF48452 681 829 1.25E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS05705 e83da977eb605c4679950101748e6f99 1021 SUPERFAMILY SSF54001 275 387 2.94E-10 T 28-03-2018 MKLM6_RS05705 e83da977eb605c4679950101748e6f99 1021 SMART SM00460 318 387 0.0071 T 28-03-2018 IPR002931 Transglutaminase-like MKLM6_RS05705 e83da977eb605c4679950101748e6f99 1021 SUPERFAMILY SSF48452 852 1008 1.52E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS12930 2006af3544d90dbf421cb442941f0063 222 Pfam PF04445 Putative SAM-dependent methyltransferase 11 221 3.0E-49 T 28-03-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 MKLM6_RS12930 2006af3544d90dbf421cb442941f0063 222 SUPERFAMILY SSF53335 36 221 1.34E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS12930 2006af3544d90dbf421cb442941f0063 222 Gene3D G3DSA:3.40.50.150 40 222 1.1E-29 T 28-03-2018 MKLM6_RS12930 2006af3544d90dbf421cb442941f0063 222 Hamap MF_01523 Ribosomal RNA small subunit methyltransferase J [rsmJ]. 1 222 23.415 T 28-03-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 MKLM6_RS00495 1b746123ebac9bb8aa3e38ed63d8c9c7 646 Pfam PF17152 Periplasmic sensor domain 44 140 9.5E-15 T 28-03-2018 IPR033417 Periplasmic sensor domain CHASE8 MKLM6_RS00495 1b746123ebac9bb8aa3e38ed63d8c9c7 646 Gene3D G3DSA:3.30.450.20 52 261 2.1E-4 T 28-03-2018 MKLM6_RS00495 1b746123ebac9bb8aa3e38ed63d8c9c7 646 SUPERFAMILY SSF55874 311 480 4.98E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS00495 1b746123ebac9bb8aa3e38ed63d8c9c7 646 Pfam PF00072 Response regulator receiver domain 516 627 8.7E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS00495 1b746123ebac9bb8aa3e38ed63d8c9c7 646 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 463 7.4E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS00495 1b746123ebac9bb8aa3e38ed63d8c9c7 646 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 424 7.4E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS00495 1b746123ebac9bb8aa3e38ed63d8c9c7 646 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 482 7.4E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS00495 1b746123ebac9bb8aa3e38ed63d8c9c7 646 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 438 7.4E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS00495 1b746123ebac9bb8aa3e38ed63d8c9c7 646 SMART SM00388 257 322 9.2E-25 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS00495 1b746123ebac9bb8aa3e38ed63d8c9c7 646 Gene3D G3DSA:3.40.50.2300 511 643 2.5E-39 T 28-03-2018 MKLM6_RS00495 1b746123ebac9bb8aa3e38ed63d8c9c7 646 SMART SM00387 369 485 4.7E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS00495 1b746123ebac9bb8aa3e38ed63d8c9c7 646 Pfam PF00512 His Kinase A (phospho-acceptor) domain 257 322 2.1E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS00495 1b746123ebac9bb8aa3e38ed63d8c9c7 646 SUPERFAMILY SSF47384 242 324 4.12E-22 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS00495 1b746123ebac9bb8aa3e38ed63d8c9c7 646 SMART SM00304 178 231 4.4E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS00495 1b746123ebac9bb8aa3e38ed63d8c9c7 646 Gene3D G3DSA:3.30.565.10 326 493 2.3E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS00495 1b746123ebac9bb8aa3e38ed63d8c9c7 646 SUPERFAMILY SSF158472 178 225 4.32E-7 T 28-03-2018 MKLM6_RS00495 1b746123ebac9bb8aa3e38ed63d8c9c7 646 Pfam PF00672 HAMP domain 178 225 2.1E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS00495 1b746123ebac9bb8aa3e38ed63d8c9c7 646 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 369 482 2.2E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS00495 1b746123ebac9bb8aa3e38ed63d8c9c7 646 SUPERFAMILY SSF52172 511 631 4.98E-37 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS00495 1b746123ebac9bb8aa3e38ed63d8c9c7 646 Gene3D G3DSA:1.10.287.130 262 318 3.3E-20 T 28-03-2018 MKLM6_RS00495 1b746123ebac9bb8aa3e38ed63d8c9c7 646 SMART SM00448 514 627 3.6E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 Pfam PF00990 Diguanylate cyclase, GGDEF domain 1066 1223 5.4E-56 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 Gene3D G3DSA:3.30.450.20 802 942 1.8E-28 T 28-03-2018 MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 Gene3D G3DSA:3.30.450.20 672 801 2.6E-18 T 28-03-2018 MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 SMART SM00091 304 373 1.5E-6 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 SMART SM00091 691 758 5.9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 SMART SM00091 941 1007 3.3E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 SMART SM00091 435 502 38.0 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 SMART SM00091 563 629 2.2 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 SMART SM00091 819 886 2.4E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 SMART SM00267 1055 1227 2.3E-76 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 SMART SM00052 1237 1484 1.8E-101 T 28-03-2018 IPR001633 EAL domain MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 Gene3D G3DSA:3.30.450.20 432 553 1.9E-19 T 28-03-2018 MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 Gene3D G3DSA:3.30.450.20 554 671 5.6E-12 T 28-03-2018 MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 SUPERFAMILY SSF55785 293 421 1.06E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 Pfam PF08448 PAS fold 442 552 3.0E-15 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 Pfam PF08448 PAS fold 825 934 3.1E-20 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 Gene3D G3DSA:3.30.450.20 288 431 3.0E-18 T 28-03-2018 MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 817 940 5.7E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 437 558 8.5E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 946 1061 1.3E-25 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 301 430 3.4E-11 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 SMART SM00086 890 933 2.1 T 28-03-2018 IPR001610 PAC motif MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 SMART SM00086 509 551 3.3 T 28-03-2018 IPR001610 PAC motif MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 SMART SM00086 1013 1055 8.7E-7 T 28-03-2018 IPR001610 PAC motif MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 SUPERFAMILY SSF55785 675 799 7.15E-13 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 SUPERFAMILY SSF55785 548 677 2.09E-8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 SUPERFAMILY SSF55785 947 1053 4.99E-30 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 Pfam PF12860 PAS fold 697 811 5.1E-7 T 28-03-2018 MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 Pfam PF12860 PAS fold 569 684 3.2E-10 T 28-03-2018 MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 Gene3D G3DSA:3.20.20.450 1228 1488 1.3E-92 T 28-03-2018 IPR001633 EAL domain MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 Gene3D G3DSA:3.30.450.20 943 1060 3.9E-30 T 28-03-2018 MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 Pfam PF00989 PAS fold 946 1050 4.9E-16 T 28-03-2018 IPR013767 PAS fold GO:0006355 MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 Pfam PF00989 PAS fold 305 398 4.0E-6 T 28-03-2018 IPR013767 PAS fold GO:0006355 MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 SUPERFAMILY SSF55785 804 931 2.97E-24 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 SUPERFAMILY SSF141868 1244 1488 8.24E-85 T 28-03-2018 IPR001633 EAL domain MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 SUPERFAMILY SSF55785 420 549 1.13E-19 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 Pfam PF00563 EAL domain 1243 1479 1.3E-69 T 28-03-2018 IPR001633 EAL domain MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 1064 1224 4.0E-48 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 Pfam PF05231 MASE1 17 288 5.4E-35 T 28-03-2018 IPR007895 MASE1 MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 SUPERFAMILY SSF55073 1071 1228 3.45E-53 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS07330 92d235d25b0c9bcab449d218e38edf5d 1499 Gene3D G3DSA:3.30.70.270 1061 1227 2.1E-65 T 28-03-2018 MKLM6_RS10635 04b42a08bc8e74e2082f74df619b5a9f 196 Gene3D G3DSA:1.10.1740.10 3 126 1.1E-31 T 28-03-2018 MKLM6_RS10635 04b42a08bc8e74e2082f74df619b5a9f 196 Pfam PF04542 Sigma-70 region 2 30 98 6.5E-19 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS10635 04b42a08bc8e74e2082f74df619b5a9f 196 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 52 83 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS10635 04b42a08bc8e74e2082f74df619b5a9f 196 Gene3D G3DSA:1.10.10.10 135 192 6.4E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS10635 04b42a08bc8e74e2082f74df619b5a9f 196 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 8 195 3.3E-94 T 28-03-2018 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS10635 04b42a08bc8e74e2082f74df619b5a9f 196 SUPERFAMILY SSF88659 128 191 1.48E-18 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS10635 04b42a08bc8e74e2082f74df619b5a9f 196 Pfam PF08281 Sigma-70, region 4 137 186 2.6E-18 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS10635 04b42a08bc8e74e2082f74df619b5a9f 196 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 26 191 2.2E-35 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS10635 04b42a08bc8e74e2082f74df619b5a9f 196 SUPERFAMILY SSF88946 9 112 2.98E-31 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS07265 8a92f4ab901de5fd05fe377054ac944e 346 SUPERFAMILY SSF51556 1 344 2.4E-143 T 28-03-2018 IPR032466 Metal-dependent hydrolase MKLM6_RS07265 8a92f4ab901de5fd05fe377054ac944e 346 Hamap MF_00219 Dihydroorotase [pyrC]. 2 345 42.974 T 28-03-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS07265 8a92f4ab901de5fd05fe377054ac944e 346 Pfam PF01979 Amidohydrolase family 11 311 1.2E-16 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MKLM6_RS07265 8a92f4ab901de5fd05fe377054ac944e 346 PIRSF PIRSF001237 1 346 3.9E-142 T 28-03-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS07265 8a92f4ab901de5fd05fe377054ac944e 346 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 3 345 1.9E-138 T 28-03-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS07265 8a92f4ab901de5fd05fe377054ac944e 346 ProSitePatterns PS00482 Dihydroorotase signature 1. 11 19 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS07265 8a92f4ab901de5fd05fe377054ac944e 346 ProSitePatterns PS00483 Dihydroorotase signature 2. 245 256 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS07265 8a92f4ab901de5fd05fe377054ac944e 346 Gene3D G3DSA:3.20.20.140 10 346 3.6E-54 T 28-03-2018 MKLM6_RS10915 c92dcf93f4f246d3088df5408ea9aa16 743 SUPERFAMILY SSF49299 540 625 2.22E-21 T 28-03-2018 IPR000601 PKD domain MKLM6_RS10915 c92dcf93f4f246d3088df5408ea9aa16 743 SUPERFAMILY SSF55486 282 388 4.65E-7 T 28-03-2018 MKLM6_RS10915 c92dcf93f4f246d3088df5408ea9aa16 743 Gene3D G3DSA:2.60.40.10 536 630 1.4E-22 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS10915 c92dcf93f4f246d3088df5408ea9aa16 743 Pfam PF00801 PKD domain 552 615 1.2E-11 T 28-03-2018 IPR000601 PKD domain MKLM6_RS10915 c92dcf93f4f246d3088df5408ea9aa16 743 Gene3D G3DSA:2.60.120.380 405 531 5.2E-11 T 28-03-2018 MKLM6_RS10915 c92dcf93f4f246d3088df5408ea9aa16 743 Gene3D G3DSA:3.40.390.10 227 404 6.0E-5 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 MKLM6_RS10915 c92dcf93f4f246d3088df5408ea9aa16 743 SMART SM00089 543 627 3.8E-21 T 28-03-2018 IPR022409 PKD/Chitinase domain MKLM6_RS00655 aabf71836b01c143ff11eef8a14fdbee 456 SUPERFAMILY SSF53448 1 250 2.5E-62 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS00655 aabf71836b01c143ff11eef8a14fdbee 456 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 4 453 3.2E-186 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 MKLM6_RS00655 aabf71836b01c143ff11eef8a14fdbee 456 Pfam PF12804 MobA-like NTP transferase domain 6 120 8.1E-23 T 28-03-2018 IPR025877 MobA-like NTP transferase MKLM6_RS00655 aabf71836b01c143ff11eef8a14fdbee 456 Gene3D G3DSA:2.160.10.10 243 308 9.3E-13 T 28-03-2018 MKLM6_RS00655 aabf71836b01c143ff11eef8a14fdbee 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 317 351 4.2E-6 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS00655 aabf71836b01c143ff11eef8a14fdbee 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 285 315 4.0E-5 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS00655 aabf71836b01c143ff11eef8a14fdbee 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 394 428 6.5E-10 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS00655 aabf71836b01c143ff11eef8a14fdbee 456 Gene3D G3DSA:2.160.10.10 309 437 1.4E-34 T 28-03-2018 MKLM6_RS00655 aabf71836b01c143ff11eef8a14fdbee 456 SUPERFAMILY SSF51161 261 435 3.93E-50 T 28-03-2018 IPR011004 Trimeric LpxA-like MKLM6_RS00655 aabf71836b01c143ff11eef8a14fdbee 456 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 2 451 42.082 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 MKLM6_RS00655 aabf71836b01c143ff11eef8a14fdbee 456 Gene3D G3DSA:3.90.550.10 1 242 7.9E-54 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS11295 329b0799016b387cc767dcedbcbe3a73 466 Pfam PF01050 Mannose-6-phosphate isomerase 311 461 1.8E-69 T 28-03-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 MKLM6_RS11295 329b0799016b387cc767dcedbcbe3a73 466 SUPERFAMILY SSF53448 1 277 1.13E-70 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS11295 329b0799016b387cc767dcedbcbe3a73 466 Gene3D G3DSA:2.60.120.10 334 445 8.4E-28 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS11295 329b0799016b387cc767dcedbcbe3a73 466 Gene3D G3DSA:3.90.550.10 1 333 3.6E-98 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS11295 329b0799016b387cc767dcedbcbe3a73 466 Pfam PF00483 Nucleotidyl transferase 3 282 5.9E-71 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MKLM6_RS11295 329b0799016b387cc767dcedbcbe3a73 466 SUPERFAMILY SSF51182 181 465 7.81E-83 T 28-03-2018 IPR011051 RmlC-like cupin domain MKLM6_RS11295 329b0799016b387cc767dcedbcbe3a73 466 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 1 465 2.9E-220 T 28-03-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 MKLM6_RS08365 a202a462a75fc12a776e86f25fb82638 197 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 6 175 3.9E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MKLM6_RS08365 a202a462a75fc12a776e86f25fb82638 197 Gene3D G3DSA:3.40.50.1000 73 193 1.5E-23 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS08365 a202a462a75fc12a776e86f25fb82638 197 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 179 3.6E-23 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS08365 a202a462a75fc12a776e86f25fb82638 197 Gene3D G3DSA:1.10.150.240 18 72 7.2E-14 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 MKLM6_RS08365 a202a462a75fc12a776e86f25fb82638 197 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 125 141 1.7E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MKLM6_RS08365 a202a462a75fc12a776e86f25fb82638 197 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 93 106 1.7E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MKLM6_RS08365 a202a462a75fc12a776e86f25fb82638 197 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 1.7E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MKLM6_RS08365 a202a462a75fc12a776e86f25fb82638 197 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 163 1.7E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MKLM6_RS08365 a202a462a75fc12a776e86f25fb82638 197 SUPERFAMILY SSF56784 6 186 1.23E-42 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS08365 a202a462a75fc12a776e86f25fb82638 197 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 62 179 2.8E-18 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MKLM6_RS17960 18e02a909d2b59368000c561d5542fdf 74 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 73 4.0E-32 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor MKLM6_RS17960 18e02a909d2b59368000c561d5542fdf 74 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 4.0E-19 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor MKLM6_RS17960 18e02a909d2b59368000c561d5542fdf 74 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 25.369 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor MKLM6_RS17960 18e02a909d2b59368000c561d5542fdf 74 Pfam PF01809 Haemolytic domain 4 68 7.8E-30 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor MKLM6_RS17960 18e02a909d2b59368000c561d5542fdf 74 SMART SM01234 1 68 1.4E-45 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor MKLM6_RS08910 1fc74203e6d2c0136baf90f85f0a4760 393 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 42.639 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MKLM6_RS08910 1fc74203e6d2c0136baf90f85f0a4760 393 PIRSF PIRSF001554 1 388 2.3E-147 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MKLM6_RS08910 1fc74203e6d2c0136baf90f85f0a4760 393 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 384 1.9E-155 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MKLM6_RS08910 1fc74203e6d2c0136baf90f85f0a4760 393 Pfam PF08442 ATP-grasp domain 2 203 4.1E-77 T 28-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MKLM6_RS08910 1fc74203e6d2c0136baf90f85f0a4760 393 Pfam PF00549 CoA-ligase 262 382 4.5E-25 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MKLM6_RS08910 1fc74203e6d2c0136baf90f85f0a4760 393 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 28-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MKLM6_RS08910 1fc74203e6d2c0136baf90f85f0a4760 393 Gene3D G3DSA:3.30.1490.20 21 96 4.7E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MKLM6_RS08910 1fc74203e6d2c0136baf90f85f0a4760 393 Gene3D G3DSA:3.40.50.261 240 385 1.8E-41 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MKLM6_RS08910 1fc74203e6d2c0136baf90f85f0a4760 393 SUPERFAMILY SSF56059 1 238 5.7E-78 T 28-03-2018 MKLM6_RS08910 1fc74203e6d2c0136baf90f85f0a4760 393 SUPERFAMILY SSF52210 239 384 1.05E-52 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MKLM6_RS08910 1fc74203e6d2c0136baf90f85f0a4760 393 Gene3D G3DSA:3.30.470.20 97 239 3.5E-52 T 28-03-2018 MKLM6_RS01550 0cce3211419a4a9084d35f2c115e2a21 298 Gene3D G3DSA:3.40.190.80 157 297 4.6E-15 T 28-03-2018 MKLM6_RS01550 0cce3211419a4a9084d35f2c115e2a21 298 SUPERFAMILY SSF56655 11 293 5.76E-47 T 28-03-2018 MKLM6_RS01550 0cce3211419a4a9084d35f2c115e2a21 298 Gene3D G3DSA:3.30.540.10 1 155 1.4E-32 T 28-03-2018 MKLM6_RS01550 0cce3211419a4a9084d35f2c115e2a21 298 Pfam PF00459 Inositol monophosphatase family 11 293 1.4E-40 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MKLM6_RS01550 0cce3211419a4a9084d35f2c115e2a21 298 PRINTS PR00377 Inositol monophosphatase superfamily signature 196 217 2.4E-14 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MKLM6_RS01550 0cce3211419a4a9084d35f2c115e2a21 298 PRINTS PR00377 Inositol monophosphatase superfamily signature 233 257 2.4E-14 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MKLM6_RS01550 0cce3211419a4a9084d35f2c115e2a21 298 PRINTS PR00377 Inositol monophosphatase superfamily signature 94 110 2.4E-14 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MKLM6_RS01550 0cce3211419a4a9084d35f2c115e2a21 298 PRINTS PR00377 Inositol monophosphatase superfamily signature 48 68 2.4E-14 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MKLM6_RS03330 fb565f15c2c2bb2c31bf43abf049ce02 729 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 83 728 8.9E-89 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 MKLM6_RS03330 fb565f15c2c2bb2c31bf43abf049ce02 729 Gene3D G3DSA:2.40.170.20 194 729 1.5E-79 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS03330 fb565f15c2c2bb2c31bf43abf049ce02 729 Pfam PF07715 TonB-dependent Receptor Plug Domain 82 179 4.7E-21 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS03330 fb565f15c2c2bb2c31bf43abf049ce02 729 Gene3D G3DSA:2.170.130.10 43 186 3.4E-28 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS03330 fb565f15c2c2bb2c31bf43abf049ce02 729 Pfam PF00593 TonB dependent receptor 249 727 3.2E-53 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS03330 fb565f15c2c2bb2c31bf43abf049ce02 729 SUPERFAMILY SSF56935 40 729 6.92E-135 T 28-03-2018 MKLM6_RS14565 c61941757f98ee6ce25979522f45dfae 151 SUPERFAMILY SSF55811 4 143 2.84E-24 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MKLM6_RS14565 c61941757f98ee6ce25979522f45dfae 151 Pfam PF00293 NUDIX domain 6 117 2.0E-12 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MKLM6_RS14565 c61941757f98ee6ce25979522f45dfae 151 Gene3D G3DSA:3.90.79.10 1 150 2.6E-25 T 28-03-2018 MKLM6_RS15305 99a3c2b433b5486de8d3f98d4d7d7b5a 1148 Gene3D G3DSA:1.20.5.50 335 465 0.031 T 28-03-2018 MKLM6_RS15305 99a3c2b433b5486de8d3f98d4d7d7b5a 1148 SUPERFAMILY SSF52540 1028 1140 1.65E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS15305 99a3c2b433b5486de8d3f98d4d7d7b5a 1148 SUPERFAMILY SSF52540 1 173 1.65E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS15305 99a3c2b433b5486de8d3f98d4d7d7b5a 1148 Gene3D G3DSA:3.40.50.300 1 175 3.1E-21 T 28-03-2018 MKLM6_RS15305 99a3c2b433b5486de8d3f98d4d7d7b5a 1148 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1040 1106 3.7E-12 T 28-03-2018 MKLM6_RS15305 99a3c2b433b5486de8d3f98d4d7d7b5a 1148 Gene3D G3DSA:3.40.50.300 854 1148 2.5E-16 T 28-03-2018 MKLM6_RS15305 99a3c2b433b5486de8d3f98d4d7d7b5a 1148 Pfam PF13476 AAA domain 6 271 2.9E-11 T 28-03-2018 MKLM6_RS15305 99a3c2b433b5486de8d3f98d4d7d7b5a 1148 Gene3D G3DSA:1.20.120.330 516 694 7.2E-5 T 28-03-2018 MKLM6_RS15305 99a3c2b433b5486de8d3f98d4d7d7b5a 1148 Gene3D G3DSA:1.20.120.330 176 334 3.0E-4 T 28-03-2018 MKLM6_RS07370 7ec96ae98b5e6d038a1e0ec0222c3bc4 349 SMART SM00382 58 229 4.5E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS07370 7ec96ae98b5e6d038a1e0ec0222c3bc4 349 SUPERFAMILY SSF54752 270 326 4.84E-22 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal MKLM6_RS07370 7ec96ae98b5e6d038a1e0ec0222c3bc4 349 SUPERFAMILY SSF52540 4 268 7.96E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS07370 7ec96ae98b5e6d038a1e0ec0222c3bc4 349 Hamap MF_00268 Protein RecA [recA]. 5 330 51.908 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MKLM6_RS07370 7ec96ae98b5e6d038a1e0ec0222c3bc4 349 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 4 325 2.1E-172 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MKLM6_RS07370 7ec96ae98b5e6d038a1e0ec0222c3bc4 349 Gene3D G3DSA:3.30.250.10 271 327 1.8E-27 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal MKLM6_RS07370 7ec96ae98b5e6d038a1e0ec0222c3bc4 349 PRINTS PR00142 RecA protein signature 94 123 9.3E-86 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MKLM6_RS07370 7ec96ae98b5e6d038a1e0ec0222c3bc4 349 PRINTS PR00142 RecA protein signature 211 239 9.3E-86 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MKLM6_RS07370 7ec96ae98b5e6d038a1e0ec0222c3bc4 349 PRINTS PR00142 RecA protein signature 244 273 9.3E-86 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MKLM6_RS07370 7ec96ae98b5e6d038a1e0ec0222c3bc4 349 PRINTS PR00142 RecA protein signature 128 157 9.3E-86 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MKLM6_RS07370 7ec96ae98b5e6d038a1e0ec0222c3bc4 349 PRINTS PR00142 RecA protein signature 166 195 9.3E-86 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MKLM6_RS07370 7ec96ae98b5e6d038a1e0ec0222c3bc4 349 PRINTS PR00142 RecA protein signature 298 315 9.3E-86 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MKLM6_RS07370 7ec96ae98b5e6d038a1e0ec0222c3bc4 349 ProSitePatterns PS00321 recA signature. 214 222 - T 28-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 MKLM6_RS07370 7ec96ae98b5e6d038a1e0ec0222c3bc4 349 Pfam PF00154 recA bacterial DNA recombination protein 7 269 1.8E-144 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MKLM6_RS07370 7ec96ae98b5e6d038a1e0ec0222c3bc4 349 Gene3D G3DSA:3.40.50.300 26 269 3.5E-46 T 28-03-2018 MKLM6_RS09740 a86b021adf03989062be7b9465afd3dc 241 Gene3D G3DSA:2.60.120.10 8 154 2.4E-12 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS09740 a86b021adf03989062be7b9465afd3dc 241 SMART SM00100 12 130 3.6E-8 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain MKLM6_RS09740 a86b021adf03989062be7b9465afd3dc 241 Pfam PF13545 Crp-like helix-turn-helix domain 150 216 1.0E-15 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MKLM6_RS09740 a86b021adf03989062be7b9465afd3dc 241 Gene3D G3DSA:1.10.10.10 155 234 2.0E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS09740 a86b021adf03989062be7b9465afd3dc 241 SMART SM00419 162 210 4.1E-7 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MKLM6_RS09740 a86b021adf03989062be7b9465afd3dc 241 Pfam PF00027 Cyclic nucleotide-binding domain 32 116 1.1E-6 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain MKLM6_RS09740 a86b021adf03989062be7b9465afd3dc 241 SUPERFAMILY SSF46785 148 222 1.39E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS09740 a86b021adf03989062be7b9465afd3dc 241 SUPERFAMILY SSF51206 19 140 9.3E-15 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like MKLM6_RS05190 eb179523504b1c192fe3eed9143f22a9 205 PIRSF PIRSF005461 1 205 5.1E-78 T 28-03-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 MKLM6_RS05190 eb179523504b1c192fe3eed9143f22a9 205 Gene3D G3DSA:3.40.50.150 1 205 1.3E-52 T 28-03-2018 MKLM6_RS05190 eb179523504b1c192fe3eed9143f22a9 205 SUPERFAMILY SSF53335 3 205 8.36E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS05190 eb179523504b1c192fe3eed9143f22a9 205 Pfam PF01728 FtsJ-like methyltransferase 28 204 7.6E-56 T 28-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 MKLM6_RS05190 eb179523504b1c192fe3eed9143f22a9 205 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 12 205 29.591 T 28-03-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 MKLM6_RS21000 4013f5e044ef0ccd99d3dd5ab0a67ca1 819 Gene3D G3DSA:2.40.170.20 279 819 1.8E-86 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS21000 4013f5e044ef0ccd99d3dd5ab0a67ca1 819 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 171 795 2.3E-98 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 MKLM6_RS21000 4013f5e044ef0ccd99d3dd5ab0a67ca1 819 Gene3D G3DSA:2.170.130.10 126 273 7.3E-25 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS21000 4013f5e044ef0ccd99d3dd5ab0a67ca1 819 SMART SM00965 71 122 1.5E-8 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MKLM6_RS21000 4013f5e044ef0ccd99d3dd5ab0a67ca1 819 Pfam PF00593 TonB dependent receptor 342 816 3.5E-58 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS21000 4013f5e044ef0ccd99d3dd5ab0a67ca1 819 Pfam PF07715 TonB-dependent Receptor Plug Domain 169 265 9.9E-18 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS21000 4013f5e044ef0ccd99d3dd5ab0a67ca1 819 SUPERFAMILY SSF56935 129 818 5.29E-137 T 28-03-2018 MKLM6_RS08150 e6827530ae681dc6901ebf7d767dae37 386 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 MKLM6_RS08150 e6827530ae681dc6901ebf7d767dae37 386 Pfam PF00155 Aminotransferase class I and II 30 380 7.2E-57 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MKLM6_RS08150 e6827530ae681dc6901ebf7d767dae37 386 Gene3D G3DSA:3.90.1150.10 289 384 9.7E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS08150 e6827530ae681dc6901ebf7d767dae37 386 Gene3D G3DSA:3.40.640.10 45 288 2.1E-57 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS08150 e6827530ae681dc6901ebf7d767dae37 386 SUPERFAMILY SSF53383 4 383 2.37E-105 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS02570 be8d61aa54960c882ae95b923c870c58 308 Gene3D G3DSA:3.30.160.40 220 304 3.6E-24 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MKLM6_RS02570 be8d61aa54960c882ae95b923c870c58 308 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 231 247 - T 28-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MKLM6_RS02570 be8d61aa54960c882ae95b923c870c58 308 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 227 295 4.3E-20 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MKLM6_RS02570 be8d61aa54960c882ae95b923c870c58 308 Gene3D G3DSA:3.40.190.10 107 199 8.9E-38 T 28-03-2018 MKLM6_RS02570 be8d61aa54960c882ae95b923c870c58 308 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 6 213 1.2E-79 T 28-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MKLM6_RS02570 be8d61aa54960c882ae95b923c870c58 308 SUPERFAMILY SSF53850 4 219 2.12E-84 T 28-03-2018 MKLM6_RS02570 be8d61aa54960c882ae95b923c870c58 308 SUPERFAMILY SSF54782 220 307 1.7E-26 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MKLM6_RS02570 be8d61aa54960c882ae95b923c870c58 308 PIRSF PIRSF001438 1 308 3.4E-121 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MKLM6_RS02570 be8d61aa54960c882ae95b923c870c58 308 PRINTS PR00151 Porphobilinogen deaminase signature 76 95 1.2E-48 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MKLM6_RS02570 be8d61aa54960c882ae95b923c870c58 308 PRINTS PR00151 Porphobilinogen deaminase signature 124 141 1.2E-48 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MKLM6_RS02570 be8d61aa54960c882ae95b923c870c58 308 PRINTS PR00151 Porphobilinogen deaminase signature 45 65 1.2E-48 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MKLM6_RS02570 be8d61aa54960c882ae95b923c870c58 308 PRINTS PR00151 Porphobilinogen deaminase signature 230 247 1.2E-48 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MKLM6_RS02570 be8d61aa54960c882ae95b923c870c58 308 PRINTS PR00151 Porphobilinogen deaminase signature 143 160 1.2E-48 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MKLM6_RS02570 be8d61aa54960c882ae95b923c870c58 308 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 5 297 38.859 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MKLM6_RS02570 be8d61aa54960c882ae95b923c870c58 308 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 6 297 3.7E-112 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MKLM6_RS02570 be8d61aa54960c882ae95b923c870c58 308 Gene3D G3DSA:3.40.190.10 2 106 5.6E-45 T 28-03-2018 MKLM6_RS15140 d5ae8a60d6117f225400b08c49273f07 512 Hamap MF_00461 Electron transport complex subunit RsxC [rsxC]. 1 512 162.522 T 28-03-2018 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 MKLM6_RS15140 d5ae8a60d6117f225400b08c49273f07 512 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 10 442 5.3E-170 T 28-03-2018 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 MKLM6_RS15140 d5ae8a60d6117f225400b08c49273f07 512 Gene3D G3DSA:3.30.70.20 350 381 0.0089 T 28-03-2018 MKLM6_RS15140 d5ae8a60d6117f225400b08c49273f07 512 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 136 280 4.5E-45 T 28-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS15140 d5ae8a60d6117f225400b08c49273f07 512 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 412 423 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MKLM6_RS15140 d5ae8a60d6117f225400b08c49273f07 512 SUPERFAMILY SSF46548 333 442 6.1E-19 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MKLM6_RS15140 d5ae8a60d6117f225400b08c49273f07 512 SUPERFAMILY SSF142019 91 299 1.7E-54 T 28-03-2018 MKLM6_RS15140 d5ae8a60d6117f225400b08c49273f07 512 Pfam PF13237 4Fe-4S dicluster domain 369 423 8.3E-10 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MKLM6_RS15140 d5ae8a60d6117f225400b08c49273f07 512 Gene3D G3DSA:3.30.70.20 382 416 3.8E-10 T 28-03-2018 MKLM6_RS15140 d5ae8a60d6117f225400b08c49273f07 512 Pfam PF10531 SLBB domain 293 340 1.6E-9 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS15140 d5ae8a60d6117f225400b08c49273f07 512 Gene3D G3DSA:3.30.70.20 417 460 0.0023 T 28-03-2018 MKLM6_RS15140 d5ae8a60d6117f225400b08c49273f07 512 Pfam PF13375 RnfC Barrel sandwich hybrid domain 10 110 1.9E-31 T 28-03-2018 IPR026902 RnfC Barrel sandwich hybrid domain MKLM6_RS08665 9ea47765b03a2bac5d5d5bb9d4a2d4c6 386 Gene3D G3DSA:3.90.1150.10 283 386 1.4E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS08665 9ea47765b03a2bac5d5d5bb9d4a2d4c6 386 Pfam PF00155 Aminotransferase class I and II 42 381 4.1E-55 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MKLM6_RS08665 9ea47765b03a2bac5d5d5bb9d4a2d4c6 386 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 20 381 2.1E-147 T 28-03-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 MKLM6_RS08665 9ea47765b03a2bac5d5d5bb9d4a2d4c6 386 SUPERFAMILY SSF53383 5 385 3.03E-111 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS08665 9ea47765b03a2bac5d5d5bb9d4a2d4c6 386 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 236 245 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 MKLM6_RS08665 9ea47765b03a2bac5d5d5bb9d4a2d4c6 386 Hamap MF_01693 8-amino-7-oxononanoate synthase [bioF]. 4 385 50.143 T 28-03-2018 IPR022834 8-amino-7-oxononanoate synthase, Proteobacteria GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 MKLM6_RS08665 9ea47765b03a2bac5d5d5bb9d4a2d4c6 386 Gene3D G3DSA:3.40.640.10 50 282 3.6E-53 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS21935 1aeb63bd3f533aecb2ead7423e70520e 117 Gene3D G3DSA:3.30.70.1060 1 115 2.4E-39 T 28-03-2018 MKLM6_RS21935 1aeb63bd3f533aecb2ead7423e70520e 117 Pfam PF03795 YCII-related domain 1 112 1.7E-25 T 28-03-2018 IPR005545 YCII-related MKLM6_RS21935 1aeb63bd3f533aecb2ead7423e70520e 117 SUPERFAMILY SSF54909 1 113 4.83E-34 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel MKLM6_RS07495 c7d9b9abb4d7f015695e4e1bc1a3babc 1064 Pfam PF11867 Domain of unknown function (DUF3387) 774 1059 9.3E-11 T 28-03-2018 IPR021810 Protein of unknown function DUF3387 MKLM6_RS07495 c7d9b9abb4d7f015695e4e1bc1a3babc 1064 Gene3D G3DSA:3.40.50.300 223 496 1.7E-22 T 28-03-2018 MKLM6_RS07495 c7d9b9abb4d7f015695e4e1bc1a3babc 1064 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 17 219 8.4E-35 T 28-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 MKLM6_RS07495 c7d9b9abb4d7f015695e4e1bc1a3babc 1064 SUPERFAMILY SSF52540 284 530 1.36E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS07495 c7d9b9abb4d7f015695e4e1bc1a3babc 1064 Pfam PF04851 Type III restriction enzyme, res subunit 311 472 1.4E-20 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MKLM6_RS07495 c7d9b9abb4d7f015695e4e1bc1a3babc 1064 SMART SM00487 305 508 5.6E-9 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MKLM6_RS07495 c7d9b9abb4d7f015695e4e1bc1a3babc 1064 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 20 728 2.3E-151 T 28-03-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 MKLM6_RS07495 c7d9b9abb4d7f015695e4e1bc1a3babc 1064 SUPERFAMILY SSF52540 339 387 1.75E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS07495 c7d9b9abb4d7f015695e4e1bc1a3babc 1064 SUPERFAMILY SSF52540 629 712 1.75E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS07800 c9e1c9bc405e16911e6907808990ca0a 240 Gene3D G3DSA:3.30.2350.10 9 239 1.8E-56 T 28-03-2018 MKLM6_RS07800 c9e1c9bc405e16911e6907808990ca0a 240 Pfam PF00849 RNA pseudouridylate synthase 16 174 5.2E-33 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS07800 c9e1c9bc405e16911e6907808990ca0a 240 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 56 70 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS07800 c9e1c9bc405e16911e6907808990ca0a 240 SUPERFAMILY SSF55120 4 237 3.04E-59 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS18580 3a44d707d1fc61737defd884b3414129 288 Gene3D G3DSA:1.10.8.10 10 94 5.4E-20 T 28-03-2018 MKLM6_RS18580 3a44d707d1fc61737defd884b3414129 288 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 191 197 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MKLM6_RS18580 3a44d707d1fc61737defd884b3414129 288 Pfam PF05175 Methyltransferase small domain 111 202 1.4E-18 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 MKLM6_RS18580 3a44d707d1fc61737defd884b3414129 288 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 33 282 2.4E-86 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 MKLM6_RS18580 3a44d707d1fc61737defd884b3414129 288 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 12 286 42.763 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 MKLM6_RS18580 3a44d707d1fc61737defd884b3414129 288 SUPERFAMILY SSF53335 12 283 5.88E-57 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS18580 3a44d707d1fc61737defd884b3414129 288 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 17 288 2.5E-74 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 MKLM6_RS18580 3a44d707d1fc61737defd884b3414129 288 Gene3D G3DSA:3.40.50.150 95 287 2.9E-44 T 28-03-2018 MKLM6_RS18330 84a3fa1d51101fefd1affdd875570763 118 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 26.784 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18330 84a3fa1d51101fefd1affdd875570763 118 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 28-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18330 84a3fa1d51101fefd1affdd875570763 118 Gene3D G3DSA:4.10.910.10 85 118 4.5E-26 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18330 84a3fa1d51101fefd1affdd875570763 118 Pfam PF00416 Ribosomal protein S13/S18 3 108 9.7E-31 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18330 84a3fa1d51101fefd1affdd875570763 118 Gene3D G3DSA:1.10.8.50 1 66 6.1E-25 T 28-03-2018 MKLM6_RS18330 84a3fa1d51101fefd1affdd875570763 118 PIRSF PIRSF002134 1 118 1.1E-43 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18330 84a3fa1d51101fefd1affdd875570763 118 SUPERFAMILY SSF46946 2 114 2.62E-46 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MKLM6_RS18330 84a3fa1d51101fefd1affdd875570763 118 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 6.8E-53 T 28-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18330 84a3fa1d51101fefd1affdd875570763 118 Gene3D G3DSA:4.10.910.10 67 84 1.3E-19 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS21275 85334e0176bf550e9195c0ba4d464422 389 Gene3D G3DSA:3.40.50.2000 12 367 4.8E-13 T 28-03-2018 MKLM6_RS21275 85334e0176bf550e9195c0ba4d464422 389 SUPERFAMILY SSF53756 23 373 2.56E-17 T 28-03-2018 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SMART SM00448 487 600 5.1E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SMART SM00448 1290 1405 7.7E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SMART SM00448 1138 1261 2.6E-10 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SUPERFAMILY SSF52172 486 613 6.4E-38 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 Pfam PF00512 His Kinase A (phospho-acceptor) domain 201 271 5.2E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 Pfam PF00512 His Kinase A (phospho-acceptor) domain 897 962 5.1E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 Gene3D G3DSA:1.10.287.130 886 958 4.2E-17 T 28-03-2018 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 Gene3D G3DSA:1.10.287.130 185 267 1.0E-16 T 28-03-2018 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SUPERFAMILY SSF47384 185 272 1.51E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 Gene3D G3DSA:1.20.120.160 1459 1619 6.9E-14 T 28-03-2018 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 Gene3D G3DSA:3.40.50.2300 1130 1269 9.0E-17 T 28-03-2018 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SUPERFAMILY SSF47384 883 963 1.24E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 Pfam PF00072 Response regulator receiver domain 1141 1261 4.3E-10 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 Pfam PF00072 Response regulator receiver domain 1292 1405 1.5E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 Pfam PF00072 Response regulator receiver domain 489 600 1.5E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SUPERFAMILY SSF47226 1388 1401 2.49E-13 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SUPERFAMILY SSF47226 1447 1529 2.49E-13 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SUPERFAMILY SSF55874 260 424 1.2E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SMART SM00086 816 859 1.2E-4 T 28-03-2018 IPR001610 PAC motif MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SMART SM00086 688 730 2.5E-6 T 28-03-2018 IPR001610 PAC motif MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SUPERFAMILY SSF55874 951 1129 1.44E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 Pfam PF01627 Hpt domain 1467 1545 6.8E-8 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1049 1063 2.0E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1108 1121 2.0E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1084 1102 2.0E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1067 1077 2.0E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SUPERFAMILY SSF52172 1288 1410 1.34E-35 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 323 424 4.7E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1008 1123 1.8E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 Gene3D G3DSA:3.40.50.2300 1282 1429 2.8E-36 T 28-03-2018 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 Gene3D G3DSA:3.30.450.20 613 737 3.8E-34 T 28-03-2018 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 Gene3D G3DSA:3.30.450.20 8 184 1.6E-15 T 28-03-2018 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SUPERFAMILY SSF55785 621 733 1.93E-28 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 Pfam PF08447 PAS fold 639 723 8.4E-21 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 Pfam PF08447 PAS fold 766 852 3.6E-10 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SMART SM00091 11 77 6.9E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SMART SM00091 742 810 2.3 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SMART SM00091 616 682 1.1E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SMART SM00388 897 962 3.7E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SMART SM00388 200 271 1.4E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 Gene3D G3DSA:3.30.565.10 276 433 1.1E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 Gene3D G3DSA:3.30.565.10 966 1129 1.1E-47 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SUPERFAMILY SSF55785 13 128 2.26E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 Gene3D G3DSA:3.30.450.20 738 885 4.4E-27 T 28-03-2018 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SUPERFAMILY SSF52172 1137 1265 3.7E-16 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SUPERFAMILY SSF55785 727 857 6.63E-21 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 613 736 3.2E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 738 866 1.2E-13 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 Gene3D G3DSA:3.40.50.2300 469 612 3.9E-35 T 28-03-2018 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 Pfam PF08448 PAS fold 17 139 1.0E-9 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SMART SM00387 317 428 5.4E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14125 ccf36e3f147e572c45fb2a56238a7158 1639 SMART SM00387 1008 1124 3.3E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS11515 48499a82a8d6b90adcd430f0d63e37bc 77 SUPERFAMILY SSF47413 4 62 8.31E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MKLM6_RS11515 48499a82a8d6b90adcd430f0d63e37bc 77 TIGRFAM TIGR03070 couple_hipB: transcriptional regulator, y4mF family 9 64 1.5E-24 T 28-03-2018 IPR017507 Transcription regulator, HipB-like MKLM6_RS11515 48499a82a8d6b90adcd430f0d63e37bc 77 Pfam PF01381 Helix-turn-helix 14 62 4.8E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MKLM6_RS11515 48499a82a8d6b90adcd430f0d63e37bc 77 SMART SM00530 13 68 9.6E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MKLM6_RS11515 48499a82a8d6b90adcd430f0d63e37bc 77 Gene3D G3DSA:1.10.260.40 1 77 5.3E-15 T 28-03-2018 MKLM6_RS15900 ff4148e81e93aa8993a3c56b902308dd 542 SUPERFAMILY SSF52172 8 135 6.55E-26 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS15900 ff4148e81e93aa8993a3c56b902308dd 542 Gene3D G3DSA:3.40.50.2300 4 143 2.7E-24 T 28-03-2018 MKLM6_RS15900 ff4148e81e93aa8993a3c56b902308dd 542 Gene3D G3DSA:1.25.40.10 447 531 6.0E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15900 ff4148e81e93aa8993a3c56b902308dd 542 Gene3D G3DSA:1.25.40.10 252 341 4.2E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15900 ff4148e81e93aa8993a3c56b902308dd 542 SMART SM00448 8 124 7.2E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS15900 ff4148e81e93aa8993a3c56b902308dd 542 Pfam PF13432 Tetratricopeptide repeat 171 229 1.3E-4 T 28-03-2018 MKLM6_RS15900 ff4148e81e93aa8993a3c56b902308dd 542 Pfam PF00072 Response regulator receiver domain 10 124 9.5E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS15900 ff4148e81e93aa8993a3c56b902308dd 542 SUPERFAMILY SSF48452 449 485 1.02E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15900 ff4148e81e93aa8993a3c56b902308dd 542 SUPERFAMILY SSF48452 176 384 1.02E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15900 ff4148e81e93aa8993a3c56b902308dd 542 SMART SM00028 233 266 150.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15900 ff4148e81e93aa8993a3c56b902308dd 542 SMART SM00028 267 300 34.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15900 ff4148e81e93aa8993a3c56b902308dd 542 SMART SM00028 199 232 110.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15900 ff4148e81e93aa8993a3c56b902308dd 542 SMART SM00028 343 376 160.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15900 ff4148e81e93aa8993a3c56b902308dd 542 SMART SM00028 446 479 1.6E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15900 ff4148e81e93aa8993a3c56b902308dd 542 Gene3D G3DSA:1.25.40.10 342 434 1.7E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15900 ff4148e81e93aa8993a3c56b902308dd 542 Pfam PF00515 Tetratricopeptide repeat 450 478 8.9E-7 T 28-03-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 MKLM6_RS15900 ff4148e81e93aa8993a3c56b902308dd 542 Gene3D G3DSA:1.25.40.10 144 251 3.5E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS13345 fd3a7d90de14165f66fb35be17b7c7d0 526 SUPERFAMILY SSF52540 7 274 7.85E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS13345 fd3a7d90de14165f66fb35be17b7c7d0 526 SUPERFAMILY SSF50447 258 386 6.41E-28 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain MKLM6_RS13345 fd3a7d90de14165f66fb35be17b7c7d0 526 Gene3D G3DSA:3.40.50.300 5 267 2.2E-35 T 28-03-2018 MKLM6_RS13345 fd3a7d90de14165f66fb35be17b7c7d0 526 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 2 524 52.801 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 MKLM6_RS13345 fd3a7d90de14165f66fb35be17b7c7d0 526 Pfam PF03144 Elongation factor Tu domain 2 311 377 1.1E-8 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MKLM6_RS13345 fd3a7d90de14165f66fb35be17b7c7d0 526 Pfam PF00009 Elongation factor Tu GTP binding domain 10 274 3.4E-48 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS13345 fd3a7d90de14165f66fb35be17b7c7d0 526 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 56 71 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site MKLM6_RS13345 fd3a7d90de14165f66fb35be17b7c7d0 526 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 157 2.2E-19 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MKLM6_RS13345 fd3a7d90de14165f66fb35be17b7c7d0 526 SUPERFAMILY SSF54980 389 462 5.04E-16 T 28-03-2018 IPR035647 EF-G domain III/V-like MKLM6_RS13345 fd3a7d90de14165f66fb35be17b7c7d0 526 Pfam PF16658 Class II release factor RF3, C-terminal domain 384 511 1.5E-43 T 28-03-2018 IPR032090 Peptide chain release factor 3, C-terminal MKLM6_RS13345 fd3a7d90de14165f66fb35be17b7c7d0 526 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 4 525 5.4E-255 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 MKLM6_RS13345 fd3a7d90de14165f66fb35be17b7c7d0 526 PRINTS PR00315 GTP-binding elongation factor signature 83 93 6.4E-12 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS13345 fd3a7d90de14165f66fb35be17b7c7d0 526 PRINTS PR00315 GTP-binding elongation factor signature 135 144 6.4E-12 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS13345 fd3a7d90de14165f66fb35be17b7c7d0 526 PRINTS PR00315 GTP-binding elongation factor signature 63 71 6.4E-12 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS13345 fd3a7d90de14165f66fb35be17b7c7d0 526 PRINTS PR00315 GTP-binding elongation factor signature 99 110 6.4E-12 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS13345 fd3a7d90de14165f66fb35be17b7c7d0 526 PRINTS PR00315 GTP-binding elongation factor signature 13 26 6.4E-12 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS13345 fd3a7d90de14165f66fb35be17b7c7d0 526 Gene3D G3DSA:3.30.70.870 385 462 3.4E-9 T 28-03-2018 MKLM6_RS13345 fd3a7d90de14165f66fb35be17b7c7d0 526 Gene3D G3DSA:2.40.30.10 268 381 3.7E-19 T 28-03-2018 MKLM6_RS01025 4a1c25f9bb0f9059b0c9d9d6a5213750 447 Pfam PF03734 L,D-transpeptidase catalytic domain 128 263 6.0E-23 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MKLM6_RS01025 4a1c25f9bb0f9059b0c9d9d6a5213750 447 Gene3D G3DSA:3.30.70.1070 369 438 6.5E-9 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 MKLM6_RS01025 4a1c25f9bb0f9059b0c9d9d6a5213750 447 SUPERFAMILY SSF141523 126 263 8.37E-33 T 28-03-2018 MKLM6_RS01025 4a1c25f9bb0f9059b0c9d9d6a5213750 447 Gene3D G3DSA:3.10.350.10 72 118 3.9E-6 T 28-03-2018 MKLM6_RS01025 4a1c25f9bb0f9059b0c9d9d6a5213750 447 SUPERFAMILY SSF110997 367 431 3.66E-9 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 MKLM6_RS01025 4a1c25f9bb0f9059b0c9d9d6a5213750 447 Pfam PF01476 LysM domain 78 117 3.9E-5 T 28-03-2018 IPR018392 LysM domain MKLM6_RS01025 4a1c25f9bb0f9059b0c9d9d6a5213750 447 Gene3D G3DSA:2.40.440.10 123 265 1.9E-32 T 28-03-2018 MKLM6_RS01025 4a1c25f9bb0f9059b0c9d9d6a5213750 447 Pfam PF05036 Sporulation related domain 367 430 1.6E-10 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 MKLM6_RS04740 a4d4856644d984a6ba0df9c00b6dcde1 196 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 5 189 7.1E-75 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 MKLM6_RS04740 a4d4856644d984a6ba0df9c00b6dcde1 196 Pfam PF02669 K+-transporting ATPase, c chain 6 188 4.6E-78 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 MKLM6_RS04740 a4d4856644d984a6ba0df9c00b6dcde1 196 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 2 190 37.158 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 MKLM6_RS04740 a4d4856644d984a6ba0df9c00b6dcde1 196 PIRSF PIRSF001296 1 193 1.2E-79 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 MKLM6_RS08880 37402791faff49abccb74f0c39c8a4ad 180 SUPERFAMILY SSF52172 2 74 7.83E-20 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS08880 37402791faff49abccb74f0c39c8a4ad 180 SMART SM00862 101 174 7.0E-15 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS08880 37402791faff49abccb74f0c39c8a4ad 180 Gene3D G3DSA:3.40.50.2300 12 86 1.6E-16 T 28-03-2018 MKLM6_RS08880 37402791faff49abccb74f0c39c8a4ad 180 Pfam PF00486 Transcriptional regulatory protein, C terminal 101 174 3.0E-16 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS08880 37402791faff49abccb74f0c39c8a4ad 180 Gene3D G3DSA:1.10.10.10 87 180 4.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS08880 37402791faff49abccb74f0c39c8a4ad 180 SUPERFAMILY SSF46894 81 175 7.65E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MKLM6_RS08880 37402791faff49abccb74f0c39c8a4ad 180 Pfam PF00072 Response regulator receiver domain 14 68 1.2E-9 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 SUPERFAMILY SSF141868 713 959 4.18E-90 T 28-03-2018 IPR001633 EAL domain MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 SUPERFAMILY SSF55785 271 397 4.79E-21 T 28-03-2018 IPR000014 PAS domain MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 287 405 1.4E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 414 526 8.3E-21 T 28-03-2018 IPR000014 PAS domain MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 151 278 2.7E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 SUPERFAMILY SSF55785 144 267 1.71E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 Gene3D G3DSA:3.30.70.270 524 697 7.7E-57 T 28-03-2018 MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 Pfam PF13493 Domain of unknown function (DUF4118) 33 133 1.3E-14 T 28-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 Gene3D G3DSA:3.30.450.20 139 274 1.1E-18 T 28-03-2018 MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 Pfam PF00990 Diguanylate cyclase, GGDEF domain 531 693 1.9E-45 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 529 696 7.4E-42 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 Pfam PF00563 EAL domain 713 948 7.4E-70 T 28-03-2018 IPR001633 EAL domain MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 Pfam PF08448 PAS fold 291 401 2.1E-20 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 Gene3D G3DSA:3.30.450.20 275 407 1.6E-27 T 28-03-2018 MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 SMART SM00086 357 399 42.0 T 28-03-2018 IPR001610 PAC motif MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 SMART SM00086 231 271 180.0 T 28-03-2018 IPR001610 PAC motif MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 SMART SM00086 478 520 1.9E-4 T 28-03-2018 IPR001610 PAC motif MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 SUPERFAMILY SSF55785 418 528 1.42E-27 T 28-03-2018 IPR000014 PAS domain MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 Gene3D G3DSA:3.40.50.10600 408 523 2.9E-25 T 28-03-2018 MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 Pfam PF13188 PAS domain 155 214 1.5E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 Gene3D G3DSA:1.20.120.620 31 130 5.4E-14 T 28-03-2018 MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 SUPERFAMILY SSF55073 536 699 4.94E-47 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 SMART SM00267 520 697 5.6E-61 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 Gene3D G3DSA:3.20.20.450 698 957 1.3E-102 T 28-03-2018 IPR001633 EAL domain MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 SMART SM00052 707 953 2.4E-113 T 28-03-2018 IPR001633 EAL domain MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 SMART SM00091 283 350 1.8E-8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 SMART SM00091 406 473 0.0053 T 28-03-2018 IPR000014 PAS domain MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 SMART SM00091 154 220 0.015 T 28-03-2018 IPR000014 PAS domain MKLM6_RS20020 23144811a22f194a14d83c6a41be4b88 963 Pfam PF13426 PAS domain 417 519 6.1E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS08235 3fa2e9436a33d12b948d583d35dd320d 197 Gene3D G3DSA:1.10.760.10 100 196 1.1E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS08235 3fa2e9436a33d12b948d583d35dd320d 197 Gene3D G3DSA:1.10.760.10 2 96 4.0E-18 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS08235 3fa2e9436a33d12b948d583d35dd320d 197 SUPERFAMILY SSF46626 14 96 1.5E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS08235 3fa2e9436a33d12b948d583d35dd320d 197 Pfam PF00034 Cytochrome c 124 195 5.6E-5 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS08235 3fa2e9436a33d12b948d583d35dd320d 197 SUPERFAMILY SSF46626 110 196 2.7E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS08235 3fa2e9436a33d12b948d583d35dd320d 197 PIRSF PIRSF000005 1 197 7.5E-53 T 28-03-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 MKLM6_RS05580 c5604bfdae045078d35096126c6ae3f9 141 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 136 9.987 T 28-03-2018 IPR022907 VapC family GO:0004540 MKLM6_RS05580 c5604bfdae045078d35096126c6ae3f9 141 SUPERFAMILY SSF88723 1 137 1.26E-26 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS05580 c5604bfdae045078d35096126c6ae3f9 141 Gene3D G3DSA:3.40.50.1010 1 139 4.9E-24 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS05580 c5604bfdae045078d35096126c6ae3f9 141 Pfam PF01850 PIN domain 2 122 1.4E-12 T 28-03-2018 IPR002716 PIN domain MKLM6_RS08230 b3ed87e5ac352650c8845b46a7dd8ce2 193 Pfam PF00578 AhpC/TSA family 25 167 6.8E-27 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MKLM6_RS08230 b3ed87e5ac352650c8845b46a7dd8ce2 193 Gene3D G3DSA:3.40.30.10 18 190 1.6E-31 T 28-03-2018 MKLM6_RS08230 b3ed87e5ac352650c8845b46a7dd8ce2 193 PIRSF PIRSF000239 20 189 2.8E-18 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MKLM6_RS08230 b3ed87e5ac352650c8845b46a7dd8ce2 193 SUPERFAMILY SSF52833 22 186 6.64E-38 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS18215 3f57aba32c9278a12420ad539345d5e4 428 Pfam PF08281 Sigma-70, region 4 129 180 1.4E-7 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS18215 3f57aba32c9278a12420ad539345d5e4 428 Gene3D G3DSA:1.10.10.10 132 228 8.1E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS18215 3f57aba32c9278a12420ad539345d5e4 428 Gene3D G3DSA:1.10.1740.10 14 98 7.2E-12 T 28-03-2018 MKLM6_RS18215 3f57aba32c9278a12420ad539345d5e4 428 Gene3D G3DSA:1.25.40.10 229 427 1.9E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18215 3f57aba32c9278a12420ad539345d5e4 428 SUPERFAMILY SSF48452 334 419 1.42E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18215 3f57aba32c9278a12420ad539345d5e4 428 SUPERFAMILY SSF48452 44 69 1.42E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18215 3f57aba32c9278a12420ad539345d5e4 428 SUPERFAMILY SSF88659 121 182 8.97E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS18215 3f57aba32c9278a12420ad539345d5e4 428 SUPERFAMILY SSF88946 26 106 2.0E-11 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS18215 3f57aba32c9278a12420ad539345d5e4 428 Pfam PF04542 Sigma-70 region 2 29 96 4.8E-7 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SUPERFAMILY SSF51126 632 647 4.12E-13 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SUPERFAMILY SSF51126 689 871 4.12E-13 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SUPERFAMILY SSF50969 3714 3808 3.84E-6 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SUPERFAMILY SSF50969 3431 3623 3.84E-6 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Pfam PF05593 RHS Repeat 3742 3778 2.5E-9 T 28-03-2018 IPR031325 RHS repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Pfam PF05593 RHS Repeat 3965 4002 1.4E-8 T 28-03-2018 IPR031325 RHS repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Pfam PF05593 RHS Repeat 3784 3819 6.9E-6 T 28-03-2018 IPR031325 RHS repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Pfam PF05593 RHS Repeat 3923 3959 1.6E-8 T 28-03-2018 IPR031325 RHS repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Pfam PF05593 RHS Repeat 3986 4022 7.3E-8 T 28-03-2018 IPR031325 RHS repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Pfam PF03527 RHS protein 4367 4400 4.7E-9 T 28-03-2018 IPR001826 RHS protein MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Gene3D G3DSA:2.60.40.10 2882 2983 1.8E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Gene3D G3DSA:2.120.10.30 3934 4110 3.7E-4 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Gene3D G3DSA:2.120.10.30 3322 3639 0.0027 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Gene3D G3DSA:2.120.10.30 3653 3877 0.054 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Pfam PF13229 Right handed beta helix region 113 256 1.2E-15 T 28-03-2018 MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Pfam PF13229 Right handed beta helix region 1247 1373 1.8E-13 T 28-03-2018 MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Gene3D G3DSA:2.60.40.10 2216 2326 5.0E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SMART SM00722 1209 1368 0.11 T 28-03-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SMART SM00722 372 530 2.7 T 28-03-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SMART SM00722 651 809 2.7 T 28-03-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SMART SM00722 930 1116 14.0 T 28-03-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SMART SM00722 119 279 24.0 T 28-03-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Gene3D G3DSA:2.60.40.1310 1994 2131 0.13 T 28-03-2018 MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Gene3D G3DSA:2.60.40.1310 1505 1628 0.39 T 28-03-2018 MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Gene3D G3DSA:2.60.40.1310 1900 1993 0.41 T 28-03-2018 MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Gene3D G3DSA:2.60.40.1310 1694 1825 2.3E-9 T 28-03-2018 MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 PRINTS PR00394 RHS protein signature 4436 4455 2.8E-8 T 28-03-2018 IPR001826 RHS protein MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 PRINTS PR00394 RHS protein signature 4413 4433 2.8E-8 T 28-03-2018 IPR001826 RHS protein MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Gene3D G3DSA:2.60.40.10 1826 1899 3.0E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SUPERFAMILY SSF51126 968 1148 1.16E-13 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SUPERFAMILY SSF51126 911 926 1.16E-13 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 3742 3783 5.7E-8 T 28-03-2018 IPR006530 YD repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 3923 3964 4.7E-7 T 28-03-2018 IPR006530 YD repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 3784 3819 5.4E-6 T 28-03-2018 IPR006530 YD repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 4056 4085 0.0025 T 28-03-2018 IPR006530 YD repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 3965 4006 2.6E-9 T 28-03-2018 IPR006530 YD repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 3503 3534 0.0018 T 28-03-2018 IPR006530 YD repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Gene3D G3DSA:2.60.40.10 2416 2508 0.0095 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SUPERFAMILY SSF51126 1188 1426 8.87E-16 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Gene3D G3DSA:2.60.40.1120 2988 3100 2.8E-6 T 28-03-2018 MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SUPERFAMILY SSF51126 56 313 1.29E-20 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Pfam PF05048 Periplasmic copper-binding protein (NosD) 983 1114 3.7E-11 T 28-03-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Pfam PF05048 Periplasmic copper-binding protein (NosD) 704 837 3.4E-11 T 28-03-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Pfam PF05048 Periplasmic copper-binding protein (NosD) 425 558 3.4E-11 T 28-03-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 4395 4469 1.6E-22 T 28-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SMART SM00710 1021 1043 1.5 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SMART SM00710 742 764 1.5 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SMART SM00710 463 485 1.5 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SMART SM00710 184 206 8.8 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SMART SM00710 1348 1369 530.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SMART SM00710 765 787 160.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SMART SM00710 231 252 530.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SMART SM00710 1301 1323 4.3 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SMART SM00710 140 162 3000.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SMART SM00710 1259 1280 3300.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SMART SM00710 789 810 530.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SMART SM00710 486 508 160.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SMART SM00710 1068 1089 530.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SMART SM00710 1324 1346 140.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SMART SM00710 1044 1066 160.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SMART SM00710 510 531 530.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SMART SM00710 163 183 830.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SMART SM00710 207 229 720.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SUPERFAMILY SSF49265 2228 2278 8.66E-6 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SUPERFAMILY SSF49265 1821 1920 8.66E-6 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Gene3D G3DSA:2.60.40.10 1451 1504 0.04 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Gene3D G3DSA:2.160.20.10 330 607 1.9E-16 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Gene3D G3DSA:2.160.20.10 892 1122 2.7E-18 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Gene3D G3DSA:2.160.20.10 20 329 3.2E-30 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Gene3D G3DSA:2.160.20.10 608 891 2.1E-16 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Gene3D G3DSA:2.60.40.10 2327 2413 5.1E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Gene3D G3DSA:2.160.20.10 1206 1450 2.8E-17 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SUPERFAMILY SSF51126 353 368 4.12E-13 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SUPERFAMILY SSF51126 410 592 4.12E-13 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Gene3D G3DSA:2.60.40.10 2769 2876 0.11 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Gene3D G3DSA:2.160.20.10 2566 2768 0.013 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 Gene3D G3DSA:2.60.40.10 3101 3230 0.014 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SUPERFAMILY SSF50998 3956 4082 1.02E-6 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MKLM6_RS22435 222291206c94cf7e6457371d40e4a655 4665 SUPERFAMILY SSF50998 3716 3823 1.02E-6 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MKLM6_RS07815 5a218c175fddf19b391e135c0c6f1e9b 683 Gene3D G3DSA:2.40.50.140 612 683 4.6E-6 T 28-03-2018 MKLM6_RS07815 5a218c175fddf19b391e135c0c6f1e9b 683 Pfam PF10592 AIPR protein 278 560 2.5E-49 T 28-03-2018 IPR018891 Abortive bacteriophage infection, resistance MKLM6_RS07815 5a218c175fddf19b391e135c0c6f1e9b 683 Gene3D G3DSA:3.40.1350.10 19 144 0.0016 T 28-03-2018 MKLM6_RS07210 124d6c8e87f68fda1fa9a494ab271552 246 SMART SM00331 18 245 2.0E-7 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS07210 124d6c8e87f68fda1fa9a494ab271552 246 Gene3D G3DSA:3.60.40.10 5 244 8.7E-34 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS07210 124d6c8e87f68fda1fa9a494ab271552 246 SUPERFAMILY SSF81606 5 244 2.49E-42 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS07210 124d6c8e87f68fda1fa9a494ab271552 246 SMART SM00332 1 243 1.3E-14 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS07210 124d6c8e87f68fda1fa9a494ab271552 246 Pfam PF13672 Protein phosphatase 2C 14 213 1.3E-11 T 28-03-2018 MKLM6_RS17790 aa3b5a9f0744b8877ee4c94ce2227f4a 404 Pfam PF00266 Aminotransferase class-V 4 365 3.1E-91 T 28-03-2018 IPR000192 Aminotransferase class V domain MKLM6_RS17790 aa3b5a9f0744b8877ee4c94ce2227f4a 404 SUPERFAMILY SSF53383 4 374 7.58E-103 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS17790 aa3b5a9f0744b8877ee4c94ce2227f4a 404 PIRSF PIRSF005572 1 381 9.4E-127 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 MKLM6_RS17790 aa3b5a9f0744b8877ee4c94ce2227f4a 404 Gene3D G3DSA:3.90.1150.10 263 381 1.1E-38 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS17790 aa3b5a9f0744b8877ee4c94ce2227f4a 404 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MKLM6_RS17790 aa3b5a9f0744b8877ee4c94ce2227f4a 404 Gene3D G3DSA:3.40.640.10 12 256 2.9E-54 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS17790 aa3b5a9f0744b8877ee4c94ce2227f4a 404 TIGRFAM TIGR03402 FeS_nifS: cysteine desulfurase NifS 4 383 8.7E-192 T 28-03-2018 IPR017772 Cysteine desulfurase NifS, bacterial/archaeal GO:0006520|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 671 696 1.2E-18 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 611 627 1.2E-18 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 496 514 1.2E-18 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 639 655 1.2E-18 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 SUPERFAMILY SSF56784 333 353 1.13E-62 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 SUPERFAMILY SSF56784 493 743 1.13E-62 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 SUPERFAMILY SSF81660 342 542 3.49E-51 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 Pfam PF00702 haloacid dehalogenase-like hydrolase 332 653 4.7E-24 T 28-03-2018 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 337 343 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 Pfam PF00122 E1-E2 ATPase 126 315 2.9E-49 T 28-03-2018 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 Gene3D G3DSA:2.70.150.10 22 235 1.5E-43 T 28-03-2018 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 SUPERFAMILY SSF52402 1072 1213 7.45E-28 T 28-03-2018 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 Gene3D G3DSA:3.40.1110.10 298 540 4.3E-48 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 Gene3D G3DSA:1.20.1110.10 541 909 2.4E-84 T 28-03-2018 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 SUPERFAMILY SSF81665 235 329 1.11E-123 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 SUPERFAMILY SSF81665 13 125 1.11E-123 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 SUPERFAMILY SSF81665 689 898 1.11E-123 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 SUPERFAMILY SSF81653 126 233 1.83E-27 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 Gene3D G3DSA:3.40.50.620 1069 1213 1.6E-29 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 Pfam PF00689 Cation transporting ATPase, C-terminus 724 895 1.0E-39 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 Gene3D G3DSA:3.40.50.620 910 1068 1.5E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 SMART SM00831 13 87 2.6E-37 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 94 356 6.3E-41 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 606 729 2.6E-35 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 Pfam PF00582 Universal stress protein family 1072 1213 2.0E-23 T 28-03-2018 IPR006016 UspA GO:0006950 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 Pfam PF00582 Universal stress protein family 928 1065 8.5E-21 T 28-03-2018 IPR006016 UspA GO:0006950 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 SUPERFAMILY SSF52402 927 1067 1.34E-24 T 28-03-2018 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 Pfam PF00690 Cation transporter/ATPase, N-terminus 14 80 2.1E-20 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 639 658 1.4E-40 T 28-03-2018 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 172 186 1.4E-40 T 28-03-2018 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 538 549 1.4E-40 T 28-03-2018 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 560 570 1.4E-40 T 28-03-2018 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 663 675 1.4E-40 T 28-03-2018 MKLM6_RS20700 ff50b7e8ec515bf14a257bb36aa00d35 1213 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 335 349 1.4E-40 T 28-03-2018 MKLM6_RS18495 82c7d5b361f95362172e55dd0fd2c964 143 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 4.0E-15 T 28-03-2018 MKLM6_RS18495 82c7d5b361f95362172e55dd0fd2c964 143 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 32.445 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18495 82c7d5b361f95362172e55dd0fd2c964 143 SUPERFAMILY SSF54747 3 73 2.35E-30 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal MKLM6_RS18495 82c7d5b361f95362172e55dd0fd2c964 143 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 2.9E-31 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal MKLM6_RS18495 82c7d5b361f95362172e55dd0fd2c964 143 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 28-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18495 82c7d5b361f95362172e55dd0fd2c964 143 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 1.4E-25 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18495 82c7d5b361f95362172e55dd0fd2c964 143 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 1.9E-69 T 28-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18495 82c7d5b361f95362172e55dd0fd2c964 143 SUPERFAMILY SSF46906 68 141 2.62E-27 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18495 82c7d5b361f95362172e55dd0fd2c964 143 Gene3D G3DSA:3.30.1550.10 3 72 2.6E-35 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal MKLM6_RS18495 82c7d5b361f95362172e55dd0fd2c964 143 SMART SM00649 9 141 2.5E-88 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18495 82c7d5b361f95362172e55dd0fd2c964 143 Gene3D G3DSA:1.10.10.250 73 141 2.2E-25 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 MKLM6_RS09695 a3411892c06668ce63cf7bfca5f156d9 515 Gene3D G3DSA:3.40.50.280 5 129 5.9E-18 T 28-03-2018 MKLM6_RS09695 a3411892c06668ce63cf7bfca5f156d9 515 TIGRFAM TIGR04367 HpnR_B12_rSAM: hopanoid C-3 methylase HpnR 1 493 2.7E-262 T 28-03-2018 IPR027564 Hopanoid C-3 methylase HpnR MKLM6_RS09695 a3411892c06668ce63cf7bfca5f156d9 515 SUPERFAMILY SSF52242 23 120 9.61E-8 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MKLM6_RS09695 a3411892c06668ce63cf7bfca5f156d9 515 Pfam PF02310 B12 binding domain 15 130 1.3E-21 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MKLM6_RS09695 a3411892c06668ce63cf7bfca5f156d9 515 Pfam PF04055 Radical SAM superfamily 190 349 5.5E-13 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS09695 a3411892c06668ce63cf7bfca5f156d9 515 SUPERFAMILY SSF102114 172 382 7.19E-28 T 28-03-2018 MKLM6_RS09695 a3411892c06668ce63cf7bfca5f156d9 515 Gene3D G3DSA:3.20.20.70 183 454 6.5E-26 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS09695 a3411892c06668ce63cf7bfca5f156d9 515 SMART SM00729 186 386 5.8E-14 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MKLM6_RS00090 2b59160499eee48303d3d15a7608e774 290 SMART SM00470 22 111 2.2E-30 T 28-03-2018 IPR003115 ParB/Sulfiredoxin MKLM6_RS00090 2b59160499eee48303d3d15a7608e774 290 Gene3D G3DSA:3.90.1530.10 16 111 1.2E-31 T 28-03-2018 MKLM6_RS00090 2b59160499eee48303d3d15a7608e774 290 SUPERFAMILY SSF110849 23 113 4.71E-28 T 28-03-2018 IPR003115 ParB/Sulfiredoxin MKLM6_RS00090 2b59160499eee48303d3d15a7608e774 290 Pfam PF02195 ParB-like nuclease domain 24 111 2.2E-26 T 28-03-2018 IPR003115 ParB/Sulfiredoxin MKLM6_RS00090 2b59160499eee48303d3d15a7608e774 290 SUPERFAMILY SSF109709 105 172 1.12E-11 T 28-03-2018 MKLM6_RS00090 2b59160499eee48303d3d15a7608e774 290 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 23 184 2.8E-41 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 MKLM6_RS00090 2b59160499eee48303d3d15a7608e774 290 Gene3D G3DSA:1.10.10.730 112 158 5.5E-5 T 28-03-2018 MKLM6_RS01735 d3aa7107eed6942c8323290f0218059c 148 Gene3D G3DSA:2.40.50.140 92 145 9.3E-10 T 28-03-2018 MKLM6_RS01735 d3aa7107eed6942c8323290f0218059c 148 Pfam PF01957 NfeD-like C-terminal, partner-binding 11 145 1.7E-26 T 28-03-2018 IPR002810 NfeD-like, C-terminal domain MKLM6_RS16980 73479663230117a8fec5e44ac7165c41 440 SUPERFAMILY SSF109604 172 344 3.81E-33 T 28-03-2018 MKLM6_RS16980 73479663230117a8fec5e44ac7165c41 440 Gene3D G3DSA:1.10.3210.10 134 346 1.2E-40 T 28-03-2018 MKLM6_RS16980 73479663230117a8fec5e44ac7165c41 440 Pfam PF11871 Domain of unknown function (DUF3391) 33 151 1.4E-23 T 28-03-2018 IPR021812 Protein of unknown function DUF3391 MKLM6_RS16980 73479663230117a8fec5e44ac7165c41 440 Pfam PF01966 HD domain 184 306 4.0E-13 T 28-03-2018 IPR006674 HD domain MKLM6_RS16980 73479663230117a8fec5e44ac7165c41 440 SMART SM00471 179 315 1.9E-7 T 28-03-2018 IPR003607 HD/PDEase domain MKLM6_RS12065 6f14554c590968f486404ea5fc43d9d2 463 Gene3D G3DSA:1.10.275.10 8 112 1.0E-37 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal MKLM6_RS12065 6f14554c590968f486404ea5fc43d9d2 463 Gene3D G3DSA:1.20.200.10 113 380 1.9E-98 T 28-03-2018 MKLM6_RS12065 6f14554c590968f486404ea5fc43d9d2 463 PRINTS PR00145 Argininosuccinate lyase family signature 237 261 4.6E-68 T 28-03-2018 MKLM6_RS12065 6f14554c590968f486404ea5fc43d9d2 463 PRINTS PR00145 Argininosuccinate lyase family signature 316 335 4.6E-68 T 28-03-2018 MKLM6_RS12065 6f14554c590968f486404ea5fc43d9d2 463 PRINTS PR00145 Argininosuccinate lyase family signature 148 168 4.6E-68 T 28-03-2018 MKLM6_RS12065 6f14554c590968f486404ea5fc43d9d2 463 PRINTS PR00145 Argininosuccinate lyase family signature 107 129 4.6E-68 T 28-03-2018 MKLM6_RS12065 6f14554c590968f486404ea5fc43d9d2 463 PRINTS PR00145 Argininosuccinate lyase family signature 199 215 4.6E-68 T 28-03-2018 MKLM6_RS12065 6f14554c590968f486404ea5fc43d9d2 463 PRINTS PR00145 Argininosuccinate lyase family signature 281 297 4.6E-68 T 28-03-2018 MKLM6_RS12065 6f14554c590968f486404ea5fc43d9d2 463 Pfam PF14698 Argininosuccinate lyase C-terminal 369 437 4.5E-24 T 28-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MKLM6_RS12065 6f14554c590968f486404ea5fc43d9d2 463 SUPERFAMILY SSF48557 12 460 1.45E-150 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 MKLM6_RS12065 6f14554c590968f486404ea5fc43d9d2 463 Hamap MF_00006 Argininosuccinate lyase [argH]. 8 459 43.018 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MKLM6_RS12065 6f14554c590968f486404ea5fc43d9d2 463 PRINTS PR00149 Fumarate lyase superfamily signature 108 126 1.9E-30 T 28-03-2018 IPR000362 Fumarate lyase family MKLM6_RS12065 6f14554c590968f486404ea5fc43d9d2 463 PRINTS PR00149 Fumarate lyase superfamily signature 281 297 1.9E-30 T 28-03-2018 IPR000362 Fumarate lyase family MKLM6_RS12065 6f14554c590968f486404ea5fc43d9d2 463 PRINTS PR00149 Fumarate lyase superfamily signature 153 171 1.9E-30 T 28-03-2018 IPR000362 Fumarate lyase family MKLM6_RS12065 6f14554c590968f486404ea5fc43d9d2 463 PRINTS PR00149 Fumarate lyase superfamily signature 237 264 1.9E-30 T 28-03-2018 IPR000362 Fumarate lyase family MKLM6_RS12065 6f14554c590968f486404ea5fc43d9d2 463 Gene3D G3DSA:1.10.40.30 381 438 9.9E-26 T 28-03-2018 MKLM6_RS12065 6f14554c590968f486404ea5fc43d9d2 463 ProSitePatterns PS00163 Fumarate lyases signature. 281 290 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MKLM6_RS12065 6f14554c590968f486404ea5fc43d9d2 463 TIGRFAM TIGR00838 argH: argininosuccinate lyase 11 461 3.8E-189 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MKLM6_RS12065 6f14554c590968f486404ea5fc43d9d2 463 Pfam PF00206 Lyase 13 306 6.0E-80 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal MKLM6_RS19000 d580334c7bc7ebc25f844088d6ac5855 541 Gene3D G3DSA:3.10.20.30 1 109 4.0E-15 T 28-03-2018 IPR012675 Beta-grasp domain MKLM6_RS19000 d580334c7bc7ebc25f844088d6ac5855 541 SUPERFAMILY SSF54292 16 102 1.14E-14 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MKLM6_RS19000 d580334c7bc7ebc25f844088d6ac5855 541 Pfam PF14574 Domain of unknown function (DUF4445) 133 532 7.6E-94 T 28-03-2018 IPR027980 Protein of unknown function DUF4445 MKLM6_RS19000 d580334c7bc7ebc25f844088d6ac5855 541 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 22 94 8.0E-9 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MKLM6_RS02110 cc1d0ae7700c7a85ba0b022bb6b9eddc 320 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 14 315 4.1E-94 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MKLM6_RS02110 cc1d0ae7700c7a85ba0b022bb6b9eddc 320 SUPERFAMILY SSF53671 12 315 2.36E-96 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MKLM6_RS02110 cc1d0ae7700c7a85ba0b022bb6b9eddc 320 Gene3D G3DSA:3.40.50.1370 13 159 2.7E-50 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MKLM6_RS02110 cc1d0ae7700c7a85ba0b022bb6b9eddc 320 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 14 158 1.7E-40 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 MKLM6_RS02110 cc1d0ae7700c7a85ba0b022bb6b9eddc 320 Gene3D G3DSA:3.40.50.1370 160 317 1.2E-57 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MKLM6_RS02110 cc1d0ae7700c7a85ba0b022bb6b9eddc 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 145 162 4.3E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MKLM6_RS02110 cc1d0ae7700c7a85ba0b022bb6b9eddc 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 295 309 4.3E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MKLM6_RS02110 cc1d0ae7700c7a85ba0b022bb6b9eddc 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 88 97 4.3E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MKLM6_RS02110 cc1d0ae7700c7a85ba0b022bb6b9eddc 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 271 276 4.3E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MKLM6_RS02110 cc1d0ae7700c7a85ba0b022bb6b9eddc 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 230 239 4.3E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MKLM6_RS02110 cc1d0ae7700c7a85ba0b022bb6b9eddc 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 50 72 4.3E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MKLM6_RS02110 cc1d0ae7700c7a85ba0b022bb6b9eddc 320 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 146 157 1.7E-20 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MKLM6_RS02110 cc1d0ae7700c7a85ba0b022bb6b9eddc 320 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 267 276 1.7E-20 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MKLM6_RS02110 cc1d0ae7700c7a85ba0b022bb6b9eddc 320 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 60 79 1.7E-20 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MKLM6_RS02110 cc1d0ae7700c7a85ba0b022bb6b9eddc 320 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 279 302 1.7E-20 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MKLM6_RS02110 cc1d0ae7700c7a85ba0b022bb6b9eddc 320 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 60 67 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MKLM6_RS02110 cc1d0ae7700c7a85ba0b022bb6b9eddc 320 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 13 316 41.297 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MKLM6_RS02110 cc1d0ae7700c7a85ba0b022bb6b9eddc 320 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 165 312 3.4E-27 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 MKLM6_RS19705 df9f23aaaba303746076f38055b979a7 545 Gene3D G3DSA:3.40.50.10490 258 508 2.9E-118 T 28-03-2018 MKLM6_RS19705 df9f23aaaba303746076f38055b979a7 545 PRINTS PR00662 Glucose-6-phosphate isomerase signature 148 167 1.3E-51 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS19705 df9f23aaaba303746076f38055b979a7 545 PRINTS PR00662 Glucose-6-phosphate isomerase signature 461 479 1.3E-51 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS19705 df9f23aaaba303746076f38055b979a7 545 PRINTS PR00662 Glucose-6-phosphate isomerase signature 260 278 1.3E-51 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS19705 df9f23aaaba303746076f38055b979a7 545 PRINTS PR00662 Glucose-6-phosphate isomerase signature 493 506 1.3E-51 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS19705 df9f23aaaba303746076f38055b979a7 545 PRINTS PR00662 Glucose-6-phosphate isomerase signature 337 358 1.3E-51 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS19705 df9f23aaaba303746076f38055b979a7 545 PRINTS PR00662 Glucose-6-phosphate isomerase signature 479 493 1.3E-51 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS19705 df9f23aaaba303746076f38055b979a7 545 Gene3D G3DSA:3.40.50.10490 137 257 9.2E-52 T 28-03-2018 MKLM6_RS19705 df9f23aaaba303746076f38055b979a7 545 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 44 520 41.275 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS19705 df9f23aaaba303746076f38055b979a7 545 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 493 510 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS19705 df9f23aaaba303746076f38055b979a7 545 Gene3D G3DSA:3.40.50.10490 5 136 2.4E-42 T 28-03-2018 MKLM6_RS19705 df9f23aaaba303746076f38055b979a7 545 Gene3D G3DSA:1.10.1390.10 509 545 1.0E-22 T 28-03-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS19705 df9f23aaaba303746076f38055b979a7 545 SUPERFAMILY SSF53697 4 544 4.45E-215 T 28-03-2018 MKLM6_RS19705 df9f23aaaba303746076f38055b979a7 545 Pfam PF00342 Phosphoglucose isomerase 50 537 7.4E-232 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS14825 00374fa99eb516c7755b555a271ba295 408 SMART SM00448 7 118 5.9E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14825 00374fa99eb516c7755b555a271ba295 408 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 209 394 5.9E-30 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS14825 00374fa99eb516c7755b555a271ba295 408 SUPERFAMILY SSF52172 8 154 6.97E-25 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS14825 00374fa99eb516c7755b555a271ba295 408 Pfam PF00072 Response regulator receiver domain 9 117 1.9E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14825 00374fa99eb516c7755b555a271ba295 408 Gene3D G3DSA:3.60.40.10 160 399 2.3E-13 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS14825 00374fa99eb516c7755b555a271ba295 408 SMART SM00331 182 398 2.7E-4 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS14825 00374fa99eb516c7755b555a271ba295 408 Gene3D G3DSA:3.40.50.2300 1 159 2.7E-24 T 28-03-2018 MKLM6_RS02715 e171f7dd07f25610448d7982b9d66a8e 148 Gene3D G3DSA:2.30.330.10 60 148 1.3E-28 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) MKLM6_RS02715 e171f7dd07f25610448d7982b9d66a8e 148 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 66 140 4.0E-33 T 28-03-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 MKLM6_RS02715 e171f7dd07f25610448d7982b9d66a8e 148 SUPERFAMILY SSF101801 66 146 2.75E-25 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) MKLM6_RS02715 e171f7dd07f25610448d7982b9d66a8e 148 PRINTS PR00956 Flagellar motor switch protein FliN signature 85 101 5.2E-28 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MKLM6_RS02715 e171f7dd07f25610448d7982b9d66a8e 148 PRINTS PR00956 Flagellar motor switch protein FliN signature 114 129 5.2E-28 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MKLM6_RS02715 e171f7dd07f25610448d7982b9d66a8e 148 PRINTS PR00956 Flagellar motor switch protein FliN signature 68 84 5.2E-28 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MKLM6_RS02715 e171f7dd07f25610448d7982b9d66a8e 148 PRINTS PR00956 Flagellar motor switch protein FliN signature 101 114 5.2E-28 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MKLM6_RS02715 e171f7dd07f25610448d7982b9d66a8e 148 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 69 138 1.4E-24 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) MKLM6_RS00340 d373a0a86f7b3f82fa6ada904b6aeb0f 340 PIRSF PIRSF029693 9 340 1.8E-106 T 28-03-2018 IPR016936 Uncharacterised conserved protein UCP029693 MKLM6_RS00340 d373a0a86f7b3f82fa6ada904b6aeb0f 340 Pfam PF10095 Uncharacterized protein conserved in bacteria (DUF2333) 13 340 7.1E-139 T 28-03-2018 IPR016936 Uncharacterised conserved protein UCP029693 MKLM6_RS03070 78ada1523b828e21dee5b0e241f30249 675 Pfam PF02630 SCO1/SenC 111 248 2.4E-9 T 28-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS03070 78ada1523b828e21dee5b0e241f30249 675 Gene3D G3DSA:1.10.760.10 474 654 3.6E-44 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS03070 78ada1523b828e21dee5b0e241f30249 675 SUPERFAMILY SSF46626 321 474 3.38E-44 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS03070 78ada1523b828e21dee5b0e241f30249 675 Gene3D G3DSA:1.10.760.10 326 473 8.2E-39 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS03070 78ada1523b828e21dee5b0e241f30249 675 SUPERFAMILY SSF52833 97 265 5.97E-21 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS03070 78ada1523b828e21dee5b0e241f30249 675 Gene3D G3DSA:3.40.30.10 89 264 2.3E-19 T 28-03-2018 MKLM6_RS03070 78ada1523b828e21dee5b0e241f30249 675 Pfam PF03150 Di-haem cytochrome c peroxidase 338 483 5.9E-44 T 28-03-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 MKLM6_RS03070 78ada1523b828e21dee5b0e241f30249 675 SUPERFAMILY SSF46626 583 652 3.36E-31 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS03070 78ada1523b828e21dee5b0e241f30249 675 SUPERFAMILY SSF46626 464 533 3.36E-31 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS04580 028ea6a58f345482b1ca49c33b92cdcd 257 Gene3D G3DSA:1.10.3130.10 6 76 6.8E-23 T 28-03-2018 MKLM6_RS04580 028ea6a58f345482b1ca49c33b92cdcd 257 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 19 179 2.2E-74 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 MKLM6_RS04580 028ea6a58f345482b1ca49c33b92cdcd 257 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 85 121 8.1E-4 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS04580 028ea6a58f345482b1ca49c33b92cdcd 257 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 130 163 9.5E-8 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS04580 028ea6a58f345482b1ca49c33b92cdcd 257 SUPERFAMILY SSF51161 9 183 1.66E-54 T 28-03-2018 IPR011004 Trimeric LpxA-like MKLM6_RS04580 028ea6a58f345482b1ca49c33b92cdcd 257 Gene3D G3DSA:2.160.10.10 77 231 1.5E-36 T 28-03-2018 MKLM6_RS04580 028ea6a58f345482b1ca49c33b92cdcd 257 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 139 167 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 Pfam PF08448 PAS fold 335 445 5.4E-17 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 SUPERFAMILY SSF47384 954 1035 8.24E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 SMART SM00448 1369 1488 6.1E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 SMART SM00448 1220 1337 1.5E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1081 1196 2.6E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 Gene3D G3DSA:3.30.450.40 491 569 2.7E-6 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 SUPERFAMILY SSF52172 1218 1349 3.42E-35 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 Pfam PF00512 His Kinase A (phospho-acceptor) domain 969 1034 2.1E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 SUPERFAMILY SSF55874 1023 1194 2.49E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 Gene3D G3DSA:1.10.287.130 973 1030 2.5E-17 T 28-03-2018 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 SUPERFAMILY SSF55785 721 818 6.14E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 325 450 1.2E-14 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 697 816 4.0E-14 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 819 938 7.6E-23 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 578 699 9.1E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 SUPERFAMILY SSF47226 1525 1666 7.59E-16 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 SMART SM00091 698 764 2.7E-4 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 SMART SM00091 581 648 0.0054 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 SMART SM00091 328 394 9.1E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 SMART SM00091 817 883 1.5E-4 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 Gene3D G3DSA:3.30.450.20 828 972 3.9E-27 T 28-03-2018 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 Gene3D G3DSA:3.30.450.20 312 459 7.4E-26 T 28-03-2018 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 Gene3D G3DSA:3.40.50.2300 1363 1543 1.6E-39 T 28-03-2018 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 SMART SM00086 889 931 5.7E-8 T 28-03-2018 IPR001610 PAC motif MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 SMART SM00086 401 443 74.0 T 28-03-2018 IPR001610 PAC motif MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 SMART SM00086 769 809 9.1 T 28-03-2018 IPR001610 PAC motif MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 SMART SM00086 653 693 5.6 T 28-03-2018 IPR001610 PAC motif MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 Gene3D G3DSA:1.20.120.160 1544 1669 1.6E-15 T 28-03-2018 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 Pfam PF01627 Hpt domain 1543 1621 7.2E-9 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 Gene3D G3DSA:3.30.565.10 1038 1208 1.3E-45 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 SUPERFAMILY SSF55785 592 701 5.15E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 Gene3D G3DSA:3.40.50.2300 1217 1362 1.8E-35 T 28-03-2018 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 SMART SM00387 1081 1198 2.7E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 SUPERFAMILY SSF55785 825 928 8.38E-30 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1122 1136 3.8E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1182 1195 3.8E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1157 1175 3.8E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1140 1150 3.8E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 Gene3D G3DSA:3.30.450.20 703 820 1.6E-15 T 28-03-2018 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 Gene3D G3DSA:3.30.450.20 570 702 7.8E-19 T 28-03-2018 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 SMART SM00388 969 1034 3.9E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 Pfam PF00072 Response regulator receiver domain 1371 1487 5.7E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 Pfam PF00072 Response regulator receiver domain 1222 1337 1.5E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 SUPERFAMILY SSF52172 1368 1494 1.34E-36 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 Pfam PF05231 MASE1 37 316 8.1E-28 T 28-03-2018 IPR007895 MASE1 MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 Pfam PF13426 PAS domain 710 808 1.0E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 Pfam PF13426 PAS domain 827 930 5.2E-17 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 Pfam PF13426 PAS domain 595 692 2.8E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14265 95e5e090cba555c70d767ec27a4947e8 1714 SUPERFAMILY SSF55785 314 441 2.44E-24 T 28-03-2018 IPR000014 PAS domain MKLM6_RS04830 528c595f28c410a149d7e955df61722b 280 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 140 2.3E-40 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MKLM6_RS04830 528c595f28c410a149d7e955df61722b 280 SUPERFAMILY SSF64518 1 280 1.44E-83 T 28-03-2018 MKLM6_RS04830 528c595f28c410a149d7e955df61722b 280 PRINTS PR00207 Flagellin signature 35 52 1.2E-21 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MKLM6_RS04830 528c595f28c410a149d7e955df61722b 280 PRINTS PR00207 Flagellin signature 74 93 1.2E-21 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MKLM6_RS04830 528c595f28c410a149d7e955df61722b 280 PRINTS PR00207 Flagellin signature 110 133 1.2E-21 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MKLM6_RS04830 528c595f28c410a149d7e955df61722b 280 Gene3D G3DSA:1.20.1330.10 38 252 5.7E-67 T 28-03-2018 MKLM6_RS04830 528c595f28c410a149d7e955df61722b 280 Pfam PF00700 Bacterial flagellin C-terminal helical region 194 279 1.2E-26 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MKLM6_RS09090 5cd6990ea73c78634770623800bece67 352 Gene3D G3DSA:3.30.420.190 126 350 8.2E-73 T 28-03-2018 MKLM6_RS09090 5cd6990ea73c78634770623800bece67 352 Gene3D G3DSA:3.30.420.40 9 124 2.8E-31 T 28-03-2018 MKLM6_RS09090 5cd6990ea73c78634770623800bece67 352 Pfam PF01968 Hydantoinase/oxoprolinase 67 316 2.8E-11 T 28-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 MKLM6_RS09090 5cd6990ea73c78634770623800bece67 352 SUPERFAMILY SSF53067 126 218 1.57E-5 T 28-03-2018 MKLM6_RS09090 5cd6990ea73c78634770623800bece67 352 SUPERFAMILY SSF53067 9 81 1.57E-5 T 28-03-2018 MKLM6_RS09090 5cd6990ea73c78634770623800bece67 352 SUPERFAMILY SSF53067 252 302 1.57E-5 T 28-03-2018 MKLM6_RS09090 5cd6990ea73c78634770623800bece67 352 TIGRFAM TIGR03123 one_C_unchar_1: probable H4MPT-linked C1 transfer pathway protein 11 348 1.5E-98 T 28-03-2018 IPR002756 4-[[4-(2-aminoethyl)phenoxy]-methyl]-2-furanmethanamine-glutamate synthase MKLM6_RS20525 b3b0ccd762802686d8559de16b7b365a 360 Gene3D G3DSA:3.40.50.2000 2 173 9.9E-40 T 28-03-2018 MKLM6_RS20525 b3b0ccd762802686d8559de16b7b365a 360 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 4 347 7.3E-102 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MKLM6_RS20525 b3b0ccd762802686d8559de16b7b365a 360 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 5 139 1.7E-41 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MKLM6_RS20525 b3b0ccd762802686d8559de16b7b365a 360 SUPERFAMILY SSF53756 4 351 3.77E-112 T 28-03-2018 MKLM6_RS20525 b3b0ccd762802686d8559de16b7b365a 360 Gene3D G3DSA:3.40.50.2000 174 340 2.1E-31 T 28-03-2018 MKLM6_RS20525 b3b0ccd762802686d8559de16b7b365a 360 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 186 340 1.3E-39 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 MKLM6_RS20525 b3b0ccd762802686d8559de16b7b365a 360 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 5 352 35.676 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MKLM6_RS13005 826cdecd1fbbcee8da2fa0281ec8f2b5 429 Pfam PF04932 O-Antigen ligase 210 328 2.3E-9 T 28-03-2018 IPR007016 O-antigen ligase-related MKLM6_RS13005 826cdecd1fbbcee8da2fa0281ec8f2b5 429 TIGRFAM TIGR03097 PEP_O_lig_1: probable O-glycosylation ligase, exosortase A-associated 2 396 2.9E-98 T 28-03-2018 IPR017528 Conserved hypothetical protein CHP03097, O-antigen ligase-related MKLM6_RS11105 6fef8c265f25e72ab0903c5d338d1415 143 SUPERFAMILY SSF109635 9 103 2.62E-36 T 28-03-2018 MKLM6_RS11105 6fef8c265f25e72ab0903c5d338d1415 143 PRINTS PR00618 DksA/TraR zinc finger signature 119 131 6.7E-5 T 28-03-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria MKLM6_RS11105 6fef8c265f25e72ab0903c5d338d1415 143 PRINTS PR00618 DksA/TraR zinc finger signature 107 118 6.7E-5 T 28-03-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria MKLM6_RS11105 6fef8c265f25e72ab0903c5d338d1415 143 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 21 143 29.968 T 28-03-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 MKLM6_RS11105 6fef8c265f25e72ab0903c5d338d1415 143 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 102 133 5.1E-12 T 28-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 MKLM6_RS11105 6fef8c265f25e72ab0903c5d338d1415 143 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 25 133 2.9E-53 T 28-03-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 MKLM6_RS11105 6fef8c265f25e72ab0903c5d338d1415 143 SUPERFAMILY SSF57716 104 141 6.41E-10 T 28-03-2018 MKLM6_RS11105 6fef8c265f25e72ab0903c5d338d1415 143 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 107 131 - T 28-03-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site MKLM6_RS03525 ea9cb0825e3cb0f53c04962de0800931 249 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 156 170 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 MKLM6_RS03525 ea9cb0825e3cb0f53c04962de0800931 249 SUPERFAMILY SSF53335 18 247 1.44E-48 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS03525 ea9cb0825e3cb0f53c04962de0800931 249 Pfam PF01209 ubiE/COQ5 methyltransferase family 19 248 1.9E-94 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MKLM6_RS03525 ea9cb0825e3cb0f53c04962de0800931 249 Gene3D G3DSA:3.40.50.150 7 248 1.3E-42 T 28-03-2018 MKLM6_RS03525 ea9cb0825e3cb0f53c04962de0800931 249 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 23 248 5.7E-85 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MKLM6_RS03525 ea9cb0825e3cb0f53c04962de0800931 249 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 34 49 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 MKLM6_RS03525 ea9cb0825e3cb0f53c04962de0800931 249 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 14 248 38.42 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MKLM6_RS07975 5f1897f517e7bb7b005325a21569622e 544 Pfam PF01740 STAS domain 437 532 9.0E-15 T 28-03-2018 IPR002645 STAS domain MKLM6_RS07975 5f1897f517e7bb7b005325a21569622e 544 Gene3D G3DSA:3.30.750.24 425 541 1.6E-20 T 28-03-2018 IPR002645 STAS domain MKLM6_RS07975 5f1897f517e7bb7b005325a21569622e 544 Pfam PF00916 Sulfate permease family 20 383 1.3E-83 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MKLM6_RS07975 5f1897f517e7bb7b005325a21569622e 544 SUPERFAMILY SSF52091 435 526 4.12E-17 T 28-03-2018 IPR002645 STAS domain MKLM6_RS00650 6fa60ea01b98110b8670f3a89ad3723f 140 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 89 131 3.9E-11 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00650 6fa60ea01b98110b8670f3a89ad3723f 140 SUPERFAMILY SSF51344 3 86 2.62E-24 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00650 6fa60ea01b98110b8670f3a89ad3723f 140 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 132 3.1E-39 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00650 6fa60ea01b98110b8670f3a89ad3723f 140 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 131 20.726 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00650 6fa60ea01b98110b8670f3a89ad3723f 140 Gene3D G3DSA:2.60.15.10 1 90 6.0E-29 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00650 6fa60ea01b98110b8670f3a89ad3723f 140 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 84 1.5E-29 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00650 6fa60ea01b98110b8670f3a89ad3723f 140 Gene3D G3DSA:1.20.5.440 91 131 5.8E-11 T 28-03-2018 MKLM6_RS00650 6fa60ea01b98110b8670f3a89ad3723f 140 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 10 90 2.0E-25 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00650 6fa60ea01b98110b8670f3a89ad3723f 140 SUPERFAMILY SSF46604 88 137 1.75E-12 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS16855 575bc428df6b6118cf8497b9b2284fcb 168 PRINTS PR01576 Peptide deformylase signature 33 62 2.0E-38 T 28-03-2018 IPR023635 Peptide deformylase MKLM6_RS16855 575bc428df6b6118cf8497b9b2284fcb 168 PRINTS PR01576 Peptide deformylase signature 89 100 2.0E-38 T 28-03-2018 IPR023635 Peptide deformylase MKLM6_RS16855 575bc428df6b6118cf8497b9b2284fcb 168 PRINTS PR01576 Peptide deformylase signature 120 149 2.0E-38 T 28-03-2018 IPR023635 Peptide deformylase MKLM6_RS16855 575bc428df6b6118cf8497b9b2284fcb 168 PRINTS PR01576 Peptide deformylase signature 101 119 2.0E-38 T 28-03-2018 IPR023635 Peptide deformylase MKLM6_RS16855 575bc428df6b6118cf8497b9b2284fcb 168 PIRSF PIRSF004749 1 168 5.4E-58 T 28-03-2018 IPR023635 Peptide deformylase MKLM6_RS16855 575bc428df6b6118cf8497b9b2284fcb 168 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 159 1.1E-57 T 28-03-2018 IPR023635 Peptide deformylase MKLM6_RS16855 575bc428df6b6118cf8497b9b2284fcb 168 Pfam PF01327 Polypeptide deformylase 5 152 3.7E-52 T 28-03-2018 IPR023635 Peptide deformylase MKLM6_RS16855 575bc428df6b6118cf8497b9b2284fcb 168 Hamap MF_00163 Peptide deformylase [def]. 2 162 30.461 T 28-03-2018 IPR023635 Peptide deformylase MKLM6_RS16855 575bc428df6b6118cf8497b9b2284fcb 168 Gene3D G3DSA:3.90.45.10 1 168 1.7E-61 T 28-03-2018 IPR023635 Peptide deformylase MKLM6_RS16855 575bc428df6b6118cf8497b9b2284fcb 168 SUPERFAMILY SSF56420 3 164 3.93E-60 T 28-03-2018 IPR023635 Peptide deformylase MKLM6_RS12880 b8263a11b1032b8366ffd3210d3bd96a 138 Gene3D G3DSA:1.20.120.330 10 138 1.3E-16 T 28-03-2018 MKLM6_RS12880 b8263a11b1032b8366ffd3210d3bd96a 138 Pfam PF05168 HEPN domain 14 120 4.2E-5 T 28-03-2018 IPR007842 HEPN domain MKLM6_RS10530 da4a3087120ac3759cd2fba887e97bd8 309 Gene3D G3DSA:2.160.10.10 178 300 1.1E-24 T 28-03-2018 MKLM6_RS10530 da4a3087120ac3759cd2fba887e97bd8 309 SUPERFAMILY SSF51161 111 293 3.74E-43 T 28-03-2018 IPR011004 Trimeric LpxA-like MKLM6_RS10530 da4a3087120ac3759cd2fba887e97bd8 309 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 250 284 4.2E-6 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS10530 da4a3087120ac3759cd2fba887e97bd8 309 Gene3D G3DSA:1.10.3130.10 59 177 3.2E-40 T 28-03-2018 MKLM6_RS10530 da4a3087120ac3759cd2fba887e97bd8 309 PIRSF PIRSF000441 122 299 3.6E-52 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 MKLM6_RS07340 0d9b9ff37701f2abd6dd468bf6ff3931 309 Pfam PF02535 ZIP Zinc transporter 169 304 1.1E-19 T 28-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 MKLM6_RS06895 d92a9af3043bfff07d8faafc8a8b3626 181 Gene3D G3DSA:1.10.286.10 1 47 1.1E-17 T 28-03-2018 MKLM6_RS06895 d92a9af3043bfff07d8faafc8a8b3626 181 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 1 179 36.78 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MKLM6_RS06895 d92a9af3043bfff07d8faafc8a8b3626 181 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 1 180 1.1E-78 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MKLM6_RS06895 d92a9af3043bfff07d8faafc8a8b3626 181 Gene3D G3DSA:3.30.1130.10 49 181 5.1E-64 T 28-03-2018 MKLM6_RS06895 d92a9af3043bfff07d8faafc8a8b3626 181 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 58 74 - T 28-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MKLM6_RS06895 d92a9af3043bfff07d8faafc8a8b3626 181 Pfam PF01227 GTP cyclohydrolase I 2 178 4.0E-76 T 28-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MKLM6_RS06895 d92a9af3043bfff07d8faafc8a8b3626 181 SUPERFAMILY SSF55620 1 179 1.41E-78 T 28-03-2018 MKLM6_RS01435 3bd6d1c2221b1d4108122ba4b3eea96b 363 Gene3D G3DSA:3.40.640.10 52 244 6.4E-29 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS01435 3bd6d1c2221b1d4108122ba4b3eea96b 363 SUPERFAMILY SSF53383 3 325 2.7E-54 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS01435 3bd6d1c2221b1d4108122ba4b3eea96b 363 Gene3D G3DSA:3.90.1150.10 245 326 1.5E-4 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS01435 3bd6d1c2221b1d4108122ba4b3eea96b 363 Pfam PF00155 Aminotransferase class I and II 62 314 4.6E-31 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MKLM6_RS01435 3bd6d1c2221b1d4108122ba4b3eea96b 363 TIGRFAM TIGR01140 L_thr_O3P_dcar: threonine-phosphate decarboxylase 4 324 1.1E-109 T 28-03-2018 IPR005860 L-threonine-O-3-phosphate decarboxylase GO:0003824|GO:0009236 KEGG: 00860+4.1.1.81|MetaCyc: PWY-5443 MKLM6_RS20060 1e2606625863b7e1bf9ed8518e7fa2fc 449 Pfam PF02875 Mur ligase family, glutamate ligase domain 313 364 1.6E-11 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MKLM6_RS20060 1e2606625863b7e1bf9ed8518e7fa2fc 449 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 448 2.0E-213 T 28-03-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 MKLM6_RS20060 1e2606625863b7e1bf9ed8518e7fa2fc 449 Pfam PF08245 Mur ligase middle domain 108 293 2.7E-25 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MKLM6_RS20060 1e2606625863b7e1bf9ed8518e7fa2fc 449 Gene3D G3DSA:3.40.50.720 1 90 1.1E-11 T 28-03-2018 MKLM6_RS20060 1e2606625863b7e1bf9ed8518e7fa2fc 449 Pfam PF01225 Mur ligase family, catalytic domain 2 102 1.1E-22 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MKLM6_RS20060 1e2606625863b7e1bf9ed8518e7fa2fc 449 Gene3D G3DSA:3.90.190.20 315 449 1.7E-22 T 28-03-2018 MKLM6_RS20060 1e2606625863b7e1bf9ed8518e7fa2fc 449 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 449 57.365 T 28-03-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 MKLM6_RS20060 1e2606625863b7e1bf9ed8518e7fa2fc 449 SUPERFAMILY SSF51984 2 90 7.32E-25 T 28-03-2018 MKLM6_RS20060 1e2606625863b7e1bf9ed8518e7fa2fc 449 SUPERFAMILY SSF53623 94 311 6.67E-54 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MKLM6_RS20060 1e2606625863b7e1bf9ed8518e7fa2fc 449 Gene3D G3DSA:3.40.1190.10 91 314 5.7E-48 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MKLM6_RS20060 1e2606625863b7e1bf9ed8518e7fa2fc 449 SUPERFAMILY SSF53244 313 447 2.75E-34 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MKLM6_RS19555 484559241cfc7e70bf299c81194ede7f 107 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 3 96 21.57 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MKLM6_RS19555 484559241cfc7e70bf299c81194ede7f 107 PIRSF PIRSF004555 1 107 2.4E-36 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MKLM6_RS19555 484559241cfc7e70bf299c81194ede7f 107 SUPERFAMILY SSF82607 9 101 5.49E-34 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MKLM6_RS19555 484559241cfc7e70bf299c81194ede7f 107 Pfam PF02575 YbaB/EbfC DNA-binding family 9 97 3.5E-34 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MKLM6_RS19555 484559241cfc7e70bf299c81194ede7f 107 Gene3D G3DSA:3.30.1310.10 1 107 5.5E-40 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MKLM6_RS19555 484559241cfc7e70bf299c81194ede7f 107 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 103 5.6E-32 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MKLM6_RS13410 e4348f4bcfc26844db66fafe9b4c622f 638 Pfam PF01464 Transglycosylase SLT domain 479 590 8.1E-26 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 MKLM6_RS13410 e4348f4bcfc26844db66fafe9b4c622f 638 Gene3D G3DSA:1.10.1240.20 398 466 5.1E-13 T 28-03-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 MKLM6_RS13410 e4348f4bcfc26844db66fafe9b4c622f 638 Gene3D G3DSA:1.10.530.10 467 634 1.5E-36 T 28-03-2018 MKLM6_RS13410 e4348f4bcfc26844db66fafe9b4c622f 638 SUPERFAMILY SSF48435 29 471 2.48E-99 T 28-03-2018 IPR016026 Lytic transglycosylase, superhelical U-shaped and linker domain GO:0004553|GO:0042597 MKLM6_RS13410 e4348f4bcfc26844db66fafe9b4c622f 638 Pfam PF14718 Soluble lytic murein transglycosylase L domain 403 466 2.5E-13 T 28-03-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 MKLM6_RS13410 e4348f4bcfc26844db66fafe9b4c622f 638 SUPERFAMILY SSF53955 473 629 3.84E-41 T 28-03-2018 IPR023346 Lysozyme-like domain MKLM6_RS13410 e4348f4bcfc26844db66fafe9b4c622f 638 Gene3D G3DSA:1.25.20.10 26 382 1.4E-37 T 28-03-2018 MKLM6_RS06470 108f046da17c2c9d28935536f7fc13bc 171 SUPERFAMILY SSF88946 9 93 2.55E-14 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS06470 108f046da17c2c9d28935536f7fc13bc 171 Gene3D G3DSA:1.10.10.10 75 166 3.2E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS06470 108f046da17c2c9d28935536f7fc13bc 171 Pfam PF04542 Sigma-70 region 2 13 77 1.1E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS06470 108f046da17c2c9d28935536f7fc13bc 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 162 6.8E-14 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS06470 108f046da17c2c9d28935536f7fc13bc 171 SUPERFAMILY SSF88659 87 163 5.67E-7 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS06470 108f046da17c2c9d28935536f7fc13bc 171 Gene3D G3DSA:1.10.1740.10 3 74 9.8E-16 T 28-03-2018 MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 SMART SM00387 383 499 5.9E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 Pfam PF00072 Response regulator receiver domain 917 1028 8.9E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 Pfam PF00072 Response regulator receiver domain 659 771 9.3E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 Gene3D G3DSA:3.40.50.2300 651 784 8.2E-38 T 28-03-2018 MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 SMART SM00073 802 900 2.2E-5 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 SUPERFAMILY SSF55073 1050 1205 7.85E-48 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 Gene3D G3DSA:3.20.20.450 1209 1472 1.3E-102 T 28-03-2018 IPR001633 EAL domain MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 SUPERFAMILY SSF55874 325 498 2.1E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 Pfam PF01627 Hpt domain 812 891 1.0E-11 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 SMART SM00304 204 256 9.1E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 SMART SM00388 271 336 6.8E-24 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 SMART SM00267 1034 1205 4.2E-65 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 Gene3D G3DSA:3.30.565.10 340 506 6.2E-48 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 SUPERFAMILY SSF47384 257 336 2.55E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 SUPERFAMILY SSF47226 786 900 9.68E-21 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 Gene3D G3DSA:3.40.50.2300 513 635 3.6E-4 T 28-03-2018 MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 384 498 2.4E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 Pfam PF00563 EAL domain 1221 1456 3.7E-76 T 28-03-2018 IPR001633 EAL domain MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 SMART SM00052 1215 1461 1.3E-123 T 28-03-2018 IPR001633 EAL domain MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 SUPERFAMILY SSF141868 1220 1466 2.88E-93 T 28-03-2018 IPR001633 EAL domain MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 SUPERFAMILY SSF52172 657 782 2.56E-36 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 Pfam PF00990 Diguanylate cyclase, GGDEF domain 1045 1200 1.1E-48 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 452 8.3E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 483 496 8.3E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 477 8.3E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 438 8.3E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 SMART SM00448 915 1028 1.3E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 SMART SM00448 657 771 7.6E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 Gene3D G3DSA:3.40.50.2300 903 1044 9.9E-38 T 28-03-2018 MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 Gene3D G3DSA:3.30.70.270 1045 1208 1.1E-58 T 28-03-2018 MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 Gene3D G3DSA:1.10.287.130 261 332 2.7E-19 T 28-03-2018 MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 Pfam PF00512 His Kinase A (phospho-acceptor) domain 272 336 5.2E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 1041 1204 1.9E-41 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 Gene3D G3DSA:1.20.120.160 785 902 2.1E-16 T 28-03-2018 MKLM6_RS20115 3a9e599da2efd5db2372ddf1f0cb0f52 1474 SUPERFAMILY SSF52172 913 1058 9.82E-38 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS02495 2249e64a016caa723d5dfb2576b44617 328 SUPERFAMILY SSF53474 6 322 1.03E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS02495 2249e64a016caa723d5dfb2576b44617 328 ProSitePatterns PS01133 Uncharacterized protein family UPF0017 signature. 230 271 - T 28-03-2018 IPR000952 AB hydrolase 4, conserved site MKLM6_RS02495 2249e64a016caa723d5dfb2576b44617 328 Gene3D G3DSA:3.40.50.1820 28 328 7.7E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS02495 2249e64a016caa723d5dfb2576b44617 328 PIRSF PIRSF005211 1 326 4.4E-107 T 28-03-2018 IPR012020 AB hydrolase 4 family MKLM6_RS02495 2249e64a016caa723d5dfb2576b44617 328 Pfam PF00561 alpha/beta hydrolase fold 57 302 5.0E-17 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS04885 f0c648e75c4206886dfd3f7d7d04bd65 261 PIRSF PIRSF000456 1 258 1.8E-88 T 28-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 MKLM6_RS04885 f0c648e75c4206886dfd3f7d7d04bd65 261 Gene3D G3DSA:2.160.10.10 1 194 3.7E-43 T 28-03-2018 MKLM6_RS04885 f0c648e75c4206886dfd3f7d7d04bd65 261 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 23 51 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MKLM6_RS04885 f0c648e75c4206886dfd3f7d7d04bd65 261 SUPERFAMILY SSF51161 4 222 1.67E-59 T 28-03-2018 IPR011004 Trimeric LpxA-like MKLM6_RS04885 f0c648e75c4206886dfd3f7d7d04bd65 261 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 32 67 1.1E-6 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS04885 f0c648e75c4206886dfd3f7d7d04bd65 261 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 106 140 5.5E-8 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS04885 f0c648e75c4206886dfd3f7d7d04bd65 261 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 5 228 1.7E-76 T 28-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 MKLM6_RS04885 f0c648e75c4206886dfd3f7d7d04bd65 261 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 177 249 1.4E-11 T 28-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 MKLM6_RS04885 f0c648e75c4206886dfd3f7d7d04bd65 261 Gene3D G3DSA:1.20.1180.10 195 255 3.5E-6 T 28-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 MKLM6_RS17945 ecf3d71e28b9d07e0078754ff35a1410 498 SUPERFAMILY SSF52200 3 138 4.84E-14 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 MKLM6_RS17945 ecf3d71e28b9d07e0078754ff35a1410 498 Gene3D G3DSA:3.40.50.10140 1 148 1.6E-18 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 MKLM6_RS17945 ecf3d71e28b9d07e0078754ff35a1410 498 Pfam PF08357 SEFIR domain 6 88 4.0E-15 T 28-03-2018 IPR013568 SEFIR domain MKLM6_RS00890 2a2a92517b8ea44e16c9afb315ade1b1 384 Gene3D G3DSA:3.30.450.90 1 97 9.3E-17 T 28-03-2018 MKLM6_RS00890 2a2a92517b8ea44e16c9afb315ade1b1 384 SUPERFAMILY SSF52540 4 336 9.75E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS00890 2a2a92517b8ea44e16c9afb315ade1b1 384 Pfam PF00437 Type II/IV secretion system protein 35 246 3.7E-38 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 MKLM6_RS00890 2a2a92517b8ea44e16c9afb315ade1b1 384 Gene3D G3DSA:3.40.50.300 98 273 1.0E-24 T 28-03-2018 MKLM6_RS00890 2a2a92517b8ea44e16c9afb315ade1b1 384 Gene3D G3DSA:3.40.50.300 274 346 7.5E-13 T 28-03-2018 MKLM6_RS00890 2a2a92517b8ea44e16c9afb315ade1b1 384 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 342 4.2E-134 T 28-03-2018 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 MKLM6_RS00890 2a2a92517b8ea44e16c9afb315ade1b1 384 SMART SM00382 122 247 0.0023 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS15275 0371c94011cf4c616aa575cc737ebd29 428 SMART SM01209 103 296 1.2E-135 T 28-03-2018 MKLM6_RS15275 0371c94011cf4c616aa575cc737ebd29 428 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 103 296 1.6E-79 T 28-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MKLM6_RS15275 0371c94011cf4c616aa575cc737ebd29 428 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 331 420 3.8E-28 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MKLM6_RS15275 0371c94011cf4c616aa575cc737ebd29 428 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 423 42.012 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MKLM6_RS15275 0371c94011cf4c616aa575cc737ebd29 428 SUPERFAMILY SSF52440 1 103 4.6E-36 T 28-03-2018 IPR016185 Pre-ATP-grasp domain MKLM6_RS15275 0371c94011cf4c616aa575cc737ebd29 428 Gene3D G3DSA:3.90.600.10 330 423 2.6E-33 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MKLM6_RS15275 0371c94011cf4c616aa575cc737ebd29 428 SMART SM01210 330 423 1.0E-48 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MKLM6_RS15275 0371c94011cf4c616aa575cc737ebd29 428 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 102 1.9E-35 T 28-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MKLM6_RS15275 0371c94011cf4c616aa575cc737ebd29 428 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 423 7.3E-177 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MKLM6_RS15275 0371c94011cf4c616aa575cc737ebd29 428 SUPERFAMILY SSF51246 329 423 8.63E-31 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MKLM6_RS15275 0371c94011cf4c616aa575cc737ebd29 428 Gene3D G3DSA:3.40.50.20 2 86 7.6E-37 T 28-03-2018 MKLM6_RS15275 0371c94011cf4c616aa575cc737ebd29 428 SUPERFAMILY SSF56059 104 322 1.08E-64 T 28-03-2018 MKLM6_RS15275 0371c94011cf4c616aa575cc737ebd29 428 Gene3D G3DSA:3.30.1490.20 87 189 1.3E-24 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MKLM6_RS15275 0371c94011cf4c616aa575cc737ebd29 428 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 290 297 - T 28-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MKLM6_RS15275 0371c94011cf4c616aa575cc737ebd29 428 Gene3D G3DSA:3.30.470.20 191 329 1.8E-58 T 28-03-2018 MKLM6_RS13135 ea97e407a35799792db98e3e46be9b30 291 Pfam PF03466 LysR substrate binding domain 88 285 1.0E-47 T 28-03-2018 IPR005119 LysR, substrate-binding MKLM6_RS13135 ea97e407a35799792db98e3e46be9b30 291 SUPERFAMILY SSF46785 1 84 9.52E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS13135 ea97e407a35799792db98e3e46be9b30 291 Gene3D G3DSA:1.10.10.10 1 82 2.0E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS13135 ea97e407a35799792db98e3e46be9b30 291 Gene3D G3DSA:3.40.190.10 177 264 1.5E-22 T 28-03-2018 MKLM6_RS13135 ea97e407a35799792db98e3e46be9b30 291 SUPERFAMILY SSF53850 88 286 5.02E-39 T 28-03-2018 MKLM6_RS13135 ea97e407a35799792db98e3e46be9b30 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.1E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS13135 ea97e407a35799792db98e3e46be9b30 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.1E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS13135 ea97e407a35799792db98e3e46be9b30 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.1E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS13135 ea97e407a35799792db98e3e46be9b30 291 Gene3D G3DSA:3.40.190.10 88 176 5.6E-24 T 28-03-2018 MKLM6_RS13135 ea97e407a35799792db98e3e46be9b30 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.3E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS01605 3369a0847e1533dfe8ec4fcedf5fa24f 197 Gene3D G3DSA:3.30.230.40 1 90 1.3E-31 T 28-03-2018 MKLM6_RS01605 3369a0847e1533dfe8ec4fcedf5fa24f 197 SUPERFAMILY SSF54211 90 180 2.66E-35 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS01605 3369a0847e1533dfe8ec4fcedf5fa24f 197 Gene3D G3DSA:3.30.230.40 92 197 1.6E-31 T 28-03-2018 MKLM6_RS01605 3369a0847e1533dfe8ec4fcedf5fa24f 197 SUPERFAMILY SSF54211 4 88 1.9E-31 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS01605 3369a0847e1533dfe8ec4fcedf5fa24f 197 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 4 197 41.88 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MKLM6_RS01605 3369a0847e1533dfe8ec4fcedf5fa24f 197 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 158 170 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MKLM6_RS01605 3369a0847e1533dfe8ec4fcedf5fa24f 197 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 33 175 4.3E-62 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MKLM6_RS01605 3369a0847e1533dfe8ec4fcedf5fa24f 197 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 63 76 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MKLM6_RS03270 6c4c900536e99ab06e05a6bb13c196d4 221 Pfam PF05175 Methyltransferase small domain 56 203 2.0E-12 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 MKLM6_RS03270 6c4c900536e99ab06e05a6bb13c196d4 221 Gene3D G3DSA:3.40.50.150 11 220 1.6E-24 T 28-03-2018 MKLM6_RS03270 6c4c900536e99ab06e05a6bb13c196d4 221 SUPERFAMILY SSF53335 26 202 6.66E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS19345 cf52321ac8f018fa2dcd884a7a7297ab 529 Pfam PF13401 AAA domain 42 170 2.6E-23 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS19345 cf52321ac8f018fa2dcd884a7a7297ab 529 Pfam PF01471 Putative peptidoglycan binding domain 456 509 1.4E-6 T 28-03-2018 IPR002477 Peptidoglycan binding-like MKLM6_RS19345 cf52321ac8f018fa2dcd884a7a7297ab 529 Gene3D G3DSA:3.90.70.10 340 447 7.2E-11 T 28-03-2018 MKLM6_RS19345 cf52321ac8f018fa2dcd884a7a7297ab 529 SMART SM00382 42 185 9.5E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS19345 cf52321ac8f018fa2dcd884a7a7297ab 529 Gene3D G3DSA:1.10.101.10 448 518 1.1E-7 T 28-03-2018 IPR002477 Peptidoglycan binding-like MKLM6_RS19345 cf52321ac8f018fa2dcd884a7a7297ab 529 SUPERFAMILY SSF52540 6 259 1.43E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS19345 cf52321ac8f018fa2dcd884a7a7297ab 529 SUPERFAMILY SSF47090 449 513 3.4E-8 T 28-03-2018 IPR002477 Peptidoglycan binding-like MKLM6_RS19345 cf52321ac8f018fa2dcd884a7a7297ab 529 Gene3D G3DSA:3.40.50.300 20 193 8.9E-14 T 28-03-2018 MKLM6_RS02460 20e561a109bb8740064f11db204cf0d3 320 Pfam PF09084 NMT1/THI5 like 46 245 2.1E-10 T 28-03-2018 IPR015168 SsuA/THI5-like MKLM6_RS02460 20e561a109bb8740064f11db204cf0d3 320 Gene3D G3DSA:3.40.190.10 38 131 3.0E-7 T 28-03-2018 MKLM6_RS02460 20e561a109bb8740064f11db204cf0d3 320 SUPERFAMILY SSF53850 22 253 5.59E-23 T 28-03-2018 MKLM6_RS02460 20e561a109bb8740064f11db204cf0d3 320 Gene3D G3DSA:3.40.190.10 132 308 6.5E-16 T 28-03-2018 MKLM6_RS08915 5234806250309d8df2a08f9e9b1855d4 295 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 292 3.7E-119 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MKLM6_RS08915 5234806250309d8df2a08f9e9b1855d4 295 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 292 38.677 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MKLM6_RS08915 5234806250309d8df2a08f9e9b1855d4 295 SMART SM00881 4 100 1.1E-33 T 28-03-2018 IPR003781 CoA-binding GO:0048037 MKLM6_RS08915 5234806250309d8df2a08f9e9b1855d4 295 Pfam PF00549 CoA-ligase 157 271 1.0E-13 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MKLM6_RS08915 5234806250309d8df2a08f9e9b1855d4 295 Gene3D G3DSA:3.40.50.261 124 295 7.0E-49 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MKLM6_RS08915 5234806250309d8df2a08f9e9b1855d4 295 SUPERFAMILY SSF52210 127 292 9.42E-50 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MKLM6_RS08915 5234806250309d8df2a08f9e9b1855d4 295 PIRSF PIRSF001553 1 295 3.9E-116 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MKLM6_RS08915 5234806250309d8df2a08f9e9b1855d4 295 PRINTS PR01798 Succinyl-CoA synthase signature 212 225 2.0E-26 T 28-03-2018 MKLM6_RS08915 5234806250309d8df2a08f9e9b1855d4 295 PRINTS PR01798 Succinyl-CoA synthase signature 244 261 2.0E-26 T 28-03-2018 MKLM6_RS08915 5234806250309d8df2a08f9e9b1855d4 295 PRINTS PR01798 Succinyl-CoA synthase signature 181 199 2.0E-26 T 28-03-2018 MKLM6_RS08915 5234806250309d8df2a08f9e9b1855d4 295 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 2.0E-26 T 28-03-2018 MKLM6_RS08915 5234806250309d8df2a08f9e9b1855d4 295 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 240 253 - T 28-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site MKLM6_RS08915 5234806250309d8df2a08f9e9b1855d4 295 Gene3D G3DSA:3.40.50.720 1 123 2.3E-41 T 28-03-2018 MKLM6_RS08915 5234806250309d8df2a08f9e9b1855d4 295 SUPERFAMILY SSF51735 1 126 9.36E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS08915 5234806250309d8df2a08f9e9b1855d4 295 Pfam PF02629 CoA binding domain 6 99 6.1E-26 T 28-03-2018 IPR003781 CoA-binding GO:0048037 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 Pfam PF00122 E1-E2 ATPase 318 497 4.6E-54 T 28-03-2018 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 SUPERFAMILY SSF81653 320 417 9.29E-30 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 Gene3D G3DSA:3.30.70.100 96 183 1.0E-14 T 28-03-2018 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 Gene3D G3DSA:3.40.1110.10 534 638 2.8E-36 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 ProSitePatterns PS01047 Heavy-metal-associated domain. 116 145 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 PRINTS PR00941 Cadmium-transporting ATPase signature 125 146 1.4E-8 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 PRINTS PR00941 Cadmium-transporting ATPase signature 114 123 1.4E-8 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 PRINTS PR00941 Cadmium-transporting ATPase signature 402 416 1.4E-8 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 PRINTS PR00941 Cadmium-transporting ATPase signature 383 399 1.4E-8 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 PRINTS PR00941 Cadmium-transporting ATPase signature 302 322 1.4E-8 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 PRINTS PR00941 Cadmium-transporting ATPase signature 322 338 1.4E-8 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 663 673 1.4E-25 T 28-03-2018 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 739 751 1.4E-25 T 28-03-2018 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 716 735 1.4E-25 T 28-03-2018 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 367 381 1.4E-25 T 28-03-2018 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 517 531 1.4E-25 T 28-03-2018 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 641 652 1.4E-25 T 28-03-2018 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 237 819 4.4E-171 T 28-03-2018 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 Gene3D G3DSA:1.20.1110.10 286 533 4.1E-45 T 28-03-2018 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 256 818 4.2E-188 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 290 802 2.8E-88 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 Pfam PF00702 haloacid dehalogenase-like hydrolase 514 730 5.3E-47 T 28-03-2018 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 Gene3D G3DSA:3.40.50.1000 639 788 2.8E-38 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 Pfam PF00403 Heavy-metal-associated domain 115 171 3.4E-7 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 SUPERFAMILY SSF56784 515 535 7.07E-60 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 SUPERFAMILY SSF56784 574 816 7.07E-60 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 SUPERFAMILY SSF55008 107 175 8.64E-14 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 SUPERFAMILY SSF81665 418 511 1.06E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 SUPERFAMILY SSF81665 298 321 1.06E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS17550 f3f32023000ed22ec1d069217c6b7a20 820 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 519 525 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MKLM6_RS15650 d34fb95e88d20794f7daec32c0a19e5c 433 Gene3D G3DSA:3.50.50.60 151 282 1.1E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS15650 d34fb95e88d20794f7daec32c0a19e5c 433 Pfam PF09242 Flavocytochrome c sulphide dehydrogenase, flavin-binding 363 432 1.2E-20 T 28-03-2018 IPR015323 Flavocytochrome c sulphide dehydrogenase, flavin-binding GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 MKLM6_RS15650 d34fb95e88d20794f7daec32c0a19e5c 433 SUPERFAMILY SSF51905 149 289 2.98E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS15650 d34fb95e88d20794f7daec32c0a19e5c 433 SUPERFAMILY SSF51905 37 142 8.39E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS15650 d34fb95e88d20794f7daec32c0a19e5c 433 SUPERFAMILY SSF51905 284 359 8.39E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS15650 d34fb95e88d20794f7daec32c0a19e5c 433 Gene3D G3DSA:3.90.760.10 364 432 6.0E-21 T 28-03-2018 IPR015323 Flavocytochrome c sulphide dehydrogenase, flavin-binding GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 MKLM6_RS15650 d34fb95e88d20794f7daec32c0a19e5c 433 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 37 140 7.0E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS15650 d34fb95e88d20794f7daec32c0a19e5c 433 SUPERFAMILY SSF55424 364 432 9.89E-12 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MKLM6_RS15650 d34fb95e88d20794f7daec32c0a19e5c 433 Gene3D G3DSA:3.50.50.60 283 358 0.036 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS15650 d34fb95e88d20794f7daec32c0a19e5c 433 Gene3D G3DSA:3.50.50.60 6 140 8.9E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS18390 d58967d414be6c23021f8ecaa3012295 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 28-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18390 d58967d414be6c23021f8ecaa3012295 122 SMART SM01374 1 122 3.1E-83 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18390 d58967d414be6c23021f8ecaa3012295 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.58 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18390 d58967d414be6c23021f8ecaa3012295 122 Gene3D G3DSA:2.40.150.20 1 122 2.9E-52 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18390 d58967d414be6c23021f8ecaa3012295 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 9.2E-54 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18390 d58967d414be6c23021f8ecaa3012295 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 3.0E-57 T 28-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 MKLM6_RS18390 d58967d414be6c23021f8ecaa3012295 122 SUPERFAMILY SSF50193 1 122 1.57E-51 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MKLM6_RS05305 d1e878ad06a33771552546ffe7646eab 743 Pfam PF02384 N-6 DNA Methylase 169 490 5.2E-51 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 MKLM6_RS05305 d1e878ad06a33771552546ffe7646eab 743 SUPERFAMILY SSF53335 11 50 1.44E-113 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS05305 d1e878ad06a33771552546ffe7646eab 743 SUPERFAMILY SSF53335 87 569 1.44E-113 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS05305 d1e878ad06a33771552546ffe7646eab 743 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 221 235 8.6E-10 T 28-03-2018 MKLM6_RS05305 d1e878ad06a33771552546ffe7646eab 743 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 306 318 8.6E-10 T 28-03-2018 MKLM6_RS05305 d1e878ad06a33771552546ffe7646eab 743 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 189 205 8.6E-10 T 28-03-2018 MKLM6_RS05305 d1e878ad06a33771552546ffe7646eab 743 Gene3D G3DSA:3.40.50.150 187 593 4.0E-41 T 28-03-2018 MKLM6_RS05305 d1e878ad06a33771552546ffe7646eab 743 Pfam PF12161 HsdM N-terminal domain 14 152 1.0E-20 T 28-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain MKLM6_RS02120 8cd7f030ebb26a5752658758de2e2d78 233 Gene3D G3DSA:3.40.50.450 25 227 2.2E-65 T 28-03-2018 MKLM6_RS02120 8cd7f030ebb26a5752658758de2e2d78 233 Pfam PF03641 Possible lysine decarboxylase 90 220 5.7E-35 T 28-03-2018 IPR031100 LOG family MKLM6_RS02120 8cd7f030ebb26a5752658758de2e2d78 233 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 48 220 5.9E-40 T 28-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG MKLM6_RS02120 8cd7f030ebb26a5752658758de2e2d78 233 SUPERFAMILY SSF102405 17 220 6.56E-62 T 28-03-2018 MKLM6_RS21930 0cea27f9009203d52129e6651282cbf4 556 Gene3D G3DSA:3.90.820.10 508 549 0.062 T 28-03-2018 MKLM6_RS21930 0cea27f9009203d52129e6651282cbf4 556 Gene3D G3DSA:3.90.820.10 291 372 0.017 T 28-03-2018 MKLM6_RS21930 0cea27f9009203d52129e6651282cbf4 556 SMART SM00978 371 550 0.0045 T 28-03-2018 IPR007379 Tim44-like domain MKLM6_RS21930 0cea27f9009203d52129e6651282cbf4 556 SUPERFAMILY SSF54427 389 506 1.58E-14 T 28-03-2018 IPR032710 NTF2-like domain MKLM6_RS21930 0cea27f9009203d52129e6651282cbf4 556 Pfam PF04280 Tim44-like domain 390 512 3.3E-14 T 28-03-2018 IPR007379 Tim44-like domain MKLM6_RS06400 ec57df436c84e95dc1f6a48a502382fd 297 Pfam PF00348 Polyprenyl synthetase 31 269 8.1E-53 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 MKLM6_RS06400 ec57df436c84e95dc1f6a48a502382fd 297 Gene3D G3DSA:1.10.600.10 1 297 4.2E-82 T 28-03-2018 IPR008949 Isoprenoid synthase domain MKLM6_RS06400 ec57df436c84e95dc1f6a48a502382fd 297 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 216 228 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site MKLM6_RS06400 ec57df436c84e95dc1f6a48a502382fd 297 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 82 98 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site MKLM6_RS06400 ec57df436c84e95dc1f6a48a502382fd 297 SUPERFAMILY SSF48576 4 285 2.08E-82 T 28-03-2018 IPR008949 Isoprenoid synthase domain MKLM6_RS11300 5b8d3a0e2db9f923279deeb5153dd195 425 SUPERFAMILY SSF143865 107 363 3.27E-35 T 28-03-2018 MKLM6_RS11300 5b8d3a0e2db9f923279deeb5153dd195 425 Pfam PF01544 CorA-like Mg2+ transporter protein 134 420 9.2E-58 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 MKLM6_RS11300 5b8d3a0e2db9f923279deeb5153dd195 425 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 122 424 2.3E-72 T 28-03-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 MKLM6_RS11300 5b8d3a0e2db9f923279deeb5153dd195 425 Gene3D G3DSA:3.30.460.20 112 231 1.2E-12 T 28-03-2018 MKLM6_RS11300 5b8d3a0e2db9f923279deeb5153dd195 425 Gene3D G3DSA:1.20.58.340 357 424 2.7E-19 T 28-03-2018 MKLM6_RS11300 5b8d3a0e2db9f923279deeb5153dd195 425 Gene3D G3DSA:1.20.58.340 239 356 3.9E-10 T 28-03-2018 MKLM6_RS11300 5b8d3a0e2db9f923279deeb5153dd195 425 SUPERFAMILY SSF158791 31 98 3.4E-8 T 28-03-2018 MKLM6_RS11300 5b8d3a0e2db9f923279deeb5153dd195 425 Gene3D G3DSA:1.10.220.30 26 111 7.4E-6 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical MKLM6_RS11300 5b8d3a0e2db9f923279deeb5153dd195 425 SUPERFAMILY SSF144083 359 422 1.57E-19 T 28-03-2018 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 673 875 1.8E-35 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 2.9E-73 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 Gene3D G3DSA:1.10.1030.10 404 538 6.4E-51 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 427 547 8.1E-41 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 Gene3D G3DSA:3.30.470.20 119 403 1.4E-67 T 28-03-2018 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 SUPERFAMILY SSF48108 396 553 8.89E-51 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 SMART SM01096 424 547 4.2E-71 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 Gene3D G3DSA:3.40.50.1380 927 1054 6.9E-35 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 709 723 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 838 845 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1052 0.0 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 SMART SM00851 955 1041 1.4E-30 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1067 13.538 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 Pfam PF02142 MGS-like domain 958 1041 1.5E-18 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 SUPERFAMILY SSF52440 557 675 3.74E-49 T 28-03-2018 IPR016185 Pre-ATP-grasp domain MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 SUPERFAMILY SSF52440 1 127 8.2E-50 T 28-03-2018 IPR016185 Pre-ATP-grasp domain MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 2.5E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 2.5E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 2.5E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 2.5E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 2.5E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 2.5E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 380 398 2.5E-66 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 SUPERFAMILY SSF56059 673 933 5.83E-104 T 28-03-2018 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 Gene3D G3DSA:3.40.50.20 4 110 1.6E-39 T 28-03-2018 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 Gene3D G3DSA:3.30.470.20 745 926 2.3E-44 T 28-03-2018 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1061 13.203 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 Gene3D G3DSA:3.30.1490.20 655 744 4.1E-22 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 SUPERFAMILY SSF56059 128 401 1.71E-109 T 28-03-2018 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 Gene3D G3DSA:3.40.50.20 539 654 6.5E-61 T 28-03-2018 MKLM6_RS05175 f18199ad6575c3fe6a5df6ded05863be 1073 SUPERFAMILY SSF52335 935 1070 1.7E-37 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain MKLM6_RS14570 813dfed26df9b0dedc65a1542771d1da 365 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 3 359 39.083 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 MKLM6_RS14570 813dfed26df9b0dedc65a1542771d1da 365 SUPERFAMILY SSF52402 2 241 7.72E-53 T 28-03-2018 MKLM6_RS14570 813dfed26df9b0dedc65a1542771d1da 365 Pfam PF03054 tRNA methyl transferase 3 358 2.0E-136 T 28-03-2018 MKLM6_RS14570 813dfed26df9b0dedc65a1542771d1da 365 Gene3D G3DSA:2.40.30.10 279 365 1.0E-26 T 28-03-2018 MKLM6_RS14570 813dfed26df9b0dedc65a1542771d1da 365 Gene3D G3DSA:2.30.30.280 210 277 3.8E-27 T 28-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 MKLM6_RS14570 813dfed26df9b0dedc65a1542771d1da 365 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 3 358 4.2E-136 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 MKLM6_RS14570 813dfed26df9b0dedc65a1542771d1da 365 Gene3D G3DSA:3.40.50.620 1 209 6.7E-62 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS03235 6c2a892134834ba82134bd30c905df9a 857 Gene3D G3DSA:3.40.50.300 552 765 7.2E-55 T 28-03-2018 MKLM6_RS03235 6c2a892134834ba82134bd30c905df9a 857 Gene3D G3DSA:1.10.1780.10 1 151 6.9E-32 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 MKLM6_RS03235 6c2a892134834ba82134bd30c905df9a 857 Gene3D G3DSA:1.10.8.60 343 547 1.9E-45 T 28-03-2018 MKLM6_RS03235 6c2a892134834ba82134bd30c905df9a 857 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 855 0.0 T 28-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 MKLM6_RS03235 6c2a892134834ba82134bd30c905df9a 857 SUPERFAMILY SSF52540 159 545 9.43E-100 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS03235 6c2a892134834ba82134bd30c905df9a 857 SMART SM00382 198 343 1.7E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS03235 6c2a892134834ba82134bd30c905df9a 857 SMART SM00382 597 755 2.8E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS03235 6c2a892134834ba82134bd30c905df9a 857 SMART SM01086 766 855 8.4E-36 T 28-03-2018 IPR019489 Clp ATPase, C-terminal MKLM6_RS03235 6c2a892134834ba82134bd30c905df9a 857 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 766 846 1.8E-24 T 28-03-2018 IPR019489 Clp ATPase, C-terminal MKLM6_RS03235 6c2a892134834ba82134bd30c905df9a 857 SUPERFAMILY SSF81923 4 156 4.61E-41 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 MKLM6_RS03235 6c2a892134834ba82134bd30c905df9a 857 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 MKLM6_RS03235 6c2a892134834ba82134bd30c905df9a 857 SUPERFAMILY SSF52540 546 854 1.28E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS03235 6c2a892134834ba82134bd30c905df9a 857 Pfam PF07724 AAA domain (Cdc48 subfamily) 596 759 2.0E-55 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MKLM6_RS03235 6c2a892134834ba82134bd30c905df9a 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 646 664 2.4E-41 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 MKLM6_RS03235 6c2a892134834ba82134bd30c905df9a 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 601 619 2.4E-41 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 MKLM6_RS03235 6c2a892134834ba82134bd30c905df9a 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 708 722 2.4E-41 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 MKLM6_RS03235 6c2a892134834ba82134bd30c905df9a 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 675 693 2.4E-41 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 MKLM6_RS03235 6c2a892134834ba82134bd30c905df9a 857 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 631 649 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 MKLM6_RS03235 6c2a892134834ba82134bd30c905df9a 857 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 334 1.2E-12 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MKLM6_RS03235 6c2a892134834ba82134bd30c905df9a 857 Gene3D G3DSA:3.40.50.300 157 342 2.9E-24 T 28-03-2018 MKLM6_RS03235 6c2a892134834ba82134bd30c905df9a 857 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 9.1E-12 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 MKLM6_RS03235 6c2a892134834ba82134bd30c905df9a 857 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 145 2.3E-13 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 MKLM6_RS03235 6c2a892134834ba82134bd30c905df9a 857 Gene3D G3DSA:1.10.8.60 766 857 3.6E-23 T 28-03-2018 MKLM6_RS12710 e98c38bf06947a7a7919c9ee654e4f0a 255 SUPERFAMILY SSF53448 5 252 8.56E-63 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS12710 e98c38bf06947a7a7919c9ee654e4f0a 255 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 5 245 1.9E-95 T 28-03-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 MKLM6_RS12710 e98c38bf06947a7a7919c9ee654e4f0a 255 Gene3D G3DSA:3.90.550.10 4 255 5.1E-50 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS12710 e98c38bf06947a7a7919c9ee654e4f0a 255 Pfam PF02348 Cytidylyltransferase 7 225 3.3E-59 T 28-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 MKLM6_RS12710 e98c38bf06947a7a7919c9ee654e4f0a 255 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 3 253 43.265 T 28-03-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 MKLM6_RS01245 800cfe2ff71dfcd675f4023bcc01d379 155 Gene3D G3DSA:1.10.1220.10 2 36 2.0E-15 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 MKLM6_RS01245 800cfe2ff71dfcd675f4023bcc01d379 155 Pfam PF01402 Ribbon-helix-helix protein, copG family 3 41 2.8E-9 T 28-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 MKLM6_RS01245 800cfe2ff71dfcd675f4023bcc01d379 155 SUPERFAMILY SSF47598 2 45 2.0E-11 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 MKLM6_RS01245 800cfe2ff71dfcd675f4023bcc01d379 155 Hamap MF_00476 Nickel-responsive regulator [nikR]. 1 132 26.254 T 28-03-2018 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 MKLM6_RS01245 800cfe2ff71dfcd675f4023bcc01d379 155 Gene3D G3DSA:3.30.70.1150 37 128 2.1E-32 T 28-03-2018 MKLM6_RS01245 800cfe2ff71dfcd675f4023bcc01d379 155 Pfam PF08753 NikR C terminal nickel binding domain 54 129 7.1E-31 T 28-03-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal MKLM6_RS01245 800cfe2ff71dfcd675f4023bcc01d379 155 SUPERFAMILY SSF55021 54 132 2.52E-25 T 28-03-2018 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 5.7E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 PRINTS PR00702 Acriflavin resistance protein family signature 448 471 5.7E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 PRINTS PR00702 Acriflavin resistance protein family signature 473 496 5.7E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 PRINTS PR00702 Acriflavin resistance protein family signature 632 646 5.7E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 PRINTS PR00702 Acriflavin resistance protein family signature 367 388 5.7E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 5.7E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 PRINTS PR00702 Acriflavin resistance protein family signature 340 363 5.7E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 PRINTS PR00702 Acriflavin resistance protein family signature 563 580 5.7E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 PRINTS PR00702 Acriflavin resistance protein family signature 395 419 5.7E-91 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 SUPERFAMILY SSF82714 734 818 1.96E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 SUPERFAMILY SSF82714 186 275 2.22E-20 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 4 1051 0.0 T 28-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 Gene3D G3DSA:3.30.70.1440 684 780 3.2E-23 T 28-03-2018 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 Pfam PF00873 AcrB/AcrD/AcrF family 4 1038 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 SUPERFAMILY SSF82693 41 134 5.75E-26 T 28-03-2018 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 Gene3D G3DSA:1.20.1640.10 823 1039 2.3E-35 T 28-03-2018 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 Gene3D G3DSA:1.20.1640.10 282 503 3.0E-48 T 28-03-2018 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 Gene3D G3DSA:3.30.70.1430 578 683 5.8E-18 T 28-03-2018 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 Gene3D G3DSA:3.30.70.1430 41 143 1.6E-25 T 28-03-2018 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 SUPERFAMILY SSF82866 300 500 6.02E-51 T 28-03-2018 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 SUPERFAMILY SSF82866 843 1036 2.49E-41 T 28-03-2018 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 SUPERFAMILY SSF82693 686 733 3.14E-26 T 28-03-2018 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 SUPERFAMILY SSF82693 820 869 3.14E-26 T 28-03-2018 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 SUPERFAMILY SSF82693 576 683 2.25E-23 T 28-03-2018 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 Gene3D G3DSA:3.30.2090.10 184 279 3.4E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 SUPERFAMILY SSF82693 140 185 7.98E-25 T 28-03-2018 MKLM6_RS06485 054ce8a29ce13d9fa3ee9efbd7006b23 1057 SUPERFAMILY SSF82693 278 333 7.98E-25 T 28-03-2018 MKLM6_RS02650 271a0cf6df642c63d03696342c9c96b8 243 Pfam PF08241 Methyltransferase domain 63 162 5.5E-16 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MKLM6_RS02650 271a0cf6df642c63d03696342c9c96b8 243 PIRSF PIRSF006325 3 243 3.1E-98 T 28-03-2018 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 MKLM6_RS02650 271a0cf6df642c63d03696342c9c96b8 243 Hamap MF_01589 Carboxy-S-adenosyl-L-methionine synthase [cmoA]. 4 242 40.06 T 28-03-2018 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 MKLM6_RS02650 271a0cf6df642c63d03696342c9c96b8 243 Gene3D G3DSA:3.40.50.150 19 243 3.3E-39 T 28-03-2018 MKLM6_RS02650 271a0cf6df642c63d03696342c9c96b8 243 SUPERFAMILY SSF53335 20 242 1.52E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS02650 271a0cf6df642c63d03696342c9c96b8 243 TIGRFAM TIGR00740 TIGR00740: tRNA (cmo5U34)-methyltransferase 5 242 1.6E-91 T 28-03-2018 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 MKLM6_RS06225 be39d0a96eadfd54ac099b365d978e32 412 Gene3D G3DSA:1.10.443.10 213 395 7.0E-23 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS06225 be39d0a96eadfd54ac099b365d978e32 412 Pfam PF13356 Arm DNA-binding domain 3 95 3.2E-15 T 28-03-2018 IPR025166 Integrase, DNA-binding domain MKLM6_RS06225 be39d0a96eadfd54ac099b365d978e32 412 Pfam PF00589 Phage integrase family 216 367 2.2E-12 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS06225 be39d0a96eadfd54ac099b365d978e32 412 SUPERFAMILY SSF56349 107 390 1.12E-56 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS06225 be39d0a96eadfd54ac099b365d978e32 412 Gene3D G3DSA:1.10.150.130 93 212 5.2E-16 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal MKLM6_RS12740 3d9f3809922d6ad42911e9945a7bb375 362 PIRSF PIRSF001456 3 357 8.4E-143 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MKLM6_RS12740 3d9f3809922d6ad42911e9945a7bb375 362 Pfam PF01264 Chorismate synthase 10 345 1.3E-140 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MKLM6_RS12740 3d9f3809922d6ad42911e9945a7bb375 362 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MKLM6_RS12740 3d9f3809922d6ad42911e9945a7bb375 362 Gene3D G3DSA:3.60.150.10 3 355 6.3E-160 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MKLM6_RS12740 3d9f3809922d6ad42911e9945a7bb375 362 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MKLM6_RS12740 3d9f3809922d6ad42911e9945a7bb375 362 Hamap MF_00300 Chorismate synthase [aroC]. 10 352 37.98 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MKLM6_RS12740 3d9f3809922d6ad42911e9945a7bb375 362 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MKLM6_RS12740 3d9f3809922d6ad42911e9945a7bb375 362 SUPERFAMILY SSF103263 4 354 3.53E-150 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MKLM6_RS12740 3d9f3809922d6ad42911e9945a7bb375 362 TIGRFAM TIGR00033 aroC: chorismate synthase 10 350 2.2E-141 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MKLM6_RS20485 cf59324f0d4edcc015e51cf7f2efbe21 312 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 7 312 38.375 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MKLM6_RS20485 cf59324f0d4edcc015e51cf7f2efbe21 312 Pfam PF01795 MraW methylase family 6 312 3.5E-111 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MKLM6_RS20485 cf59324f0d4edcc015e51cf7f2efbe21 312 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 3 311 6.7E-114 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MKLM6_RS20485 cf59324f0d4edcc015e51cf7f2efbe21 312 PIRSF PIRSF004486 2 312 2.1E-104 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MKLM6_RS20485 cf59324f0d4edcc015e51cf7f2efbe21 312 SUPERFAMILY SSF81799 117 216 4.97E-36 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MKLM6_RS20485 cf59324f0d4edcc015e51cf7f2efbe21 312 Gene3D G3DSA:1.10.150.170 120 218 1.9E-38 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MKLM6_RS20485 cf59324f0d4edcc015e51cf7f2efbe21 312 Gene3D G3DSA:3.40.50.150 6 119 1.0E-5 T 28-03-2018 MKLM6_RS20485 cf59324f0d4edcc015e51cf7f2efbe21 312 SUPERFAMILY SSF53335 216 311 1.01E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS20485 cf59324f0d4edcc015e51cf7f2efbe21 312 SUPERFAMILY SSF53335 7 116 1.01E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS05220 ed011d84b3eec210b9cc8c9c054fdbc0 417 Gene3D G3DSA:1.10.150.130 112 219 6.6E-16 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal MKLM6_RS05220 ed011d84b3eec210b9cc8c9c054fdbc0 417 Pfam PF13356 Arm DNA-binding domain 6 90 7.4E-19 T 28-03-2018 IPR025166 Integrase, DNA-binding domain MKLM6_RS05220 ed011d84b3eec210b9cc8c9c054fdbc0 417 Pfam PF00589 Phage integrase family 225 384 8.0E-17 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS05220 ed011d84b3eec210b9cc8c9c054fdbc0 417 Gene3D G3DSA:1.10.443.10 220 400 4.1E-21 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS05220 ed011d84b3eec210b9cc8c9c054fdbc0 417 SUPERFAMILY SSF56349 114 395 8.54E-55 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS01000 e5a1933f28ba0e24a759ae22ad549c50 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 2.6E-42 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS01000 e5a1933f28ba0e24a759ae22ad549c50 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 27.445 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS01000 e5a1933f28ba0e24a759ae22ad549c50 103 SUPERFAMILY SSF141091 1 102 1.7E-39 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS01000 e5a1933f28ba0e24a759ae22ad549c50 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 28-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS01000 e5a1933f28ba0e24a759ae22ad549c50 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 2.3E-41 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS14165 4cc288a8f4b168b42309aa38824a01a3 528 Pfam PF02384 N-6 DNA Methylase 71 180 1.6E-5 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 MKLM6_RS14165 4cc288a8f4b168b42309aa38824a01a3 528 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 100 114 1.4E-8 T 28-03-2018 MKLM6_RS14165 4cc288a8f4b168b42309aa38824a01a3 528 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 167 179 1.4E-8 T 28-03-2018 MKLM6_RS14165 4cc288a8f4b168b42309aa38824a01a3 528 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 75 91 1.4E-8 T 28-03-2018 MKLM6_RS14165 4cc288a8f4b168b42309aa38824a01a3 528 SUPERFAMILY SSF53335 53 282 1.02E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS14165 4cc288a8f4b168b42309aa38824a01a3 528 Gene3D G3DSA:3.40.50.150 74 421 3.5E-29 T 28-03-2018 MKLM6_RS13885 a80c42d6b18562fdc775b21773014631 487 PIRSF PIRSF017184 6 487 9.6E-130 T 28-03-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 MKLM6_RS13885 a80c42d6b18562fdc775b21773014631 487 Gene3D G3DSA:3.40.50.10260 2 218 4.0E-60 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 MKLM6_RS13885 a80c42d6b18562fdc775b21773014631 487 Gene3D G3DSA:3.40.1190.20 222 487 1.2E-46 T 28-03-2018 IPR029056 Ribokinase-like MKLM6_RS13885 a80c42d6b18562fdc775b21773014631 487 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 10 211 24.253 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 MKLM6_RS13885 a80c42d6b18562fdc775b21773014631 487 Pfam PF01256 Carbohydrate kinase 244 476 3.8E-58 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 MKLM6_RS13885 a80c42d6b18562fdc775b21773014631 487 SUPERFAMILY SSF64153 8 243 1.23E-61 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 MKLM6_RS13885 a80c42d6b18562fdc775b21773014631 487 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 221 486 22.897 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 MKLM6_RS13885 a80c42d6b18562fdc775b21773014631 487 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 10 210 4.3E-44 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 MKLM6_RS13885 a80c42d6b18562fdc775b21773014631 487 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 228 486 1.0E-71 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 MKLM6_RS13885 a80c42d6b18562fdc775b21773014631 487 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 425 435 - T 28-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site MKLM6_RS13885 a80c42d6b18562fdc775b21773014631 487 ProSitePatterns PS01049 YjeF C-terminal domain signature 1. 311 321 - T 28-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site MKLM6_RS13885 a80c42d6b18562fdc775b21773014631 487 Pfam PF03853 YjeF-related protein N-terminus 31 190 1.9E-43 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 MKLM6_RS13885 a80c42d6b18562fdc775b21773014631 487 SUPERFAMILY SSF53613 228 486 2.66E-71 T 28-03-2018 IPR029056 Ribokinase-like MKLM6_RS18420 92321fad11f9fa469891fe2368d29743 90 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 28-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18420 92321fad11f9fa469891fe2368d29743 90 Pfam PF00203 Ribosomal protein S19 3 83 3.4E-36 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18420 92321fad11f9fa469891fe2368d29743 90 SUPERFAMILY SSF54570 3 83 1.03E-34 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18420 92321fad11f9fa469891fe2368d29743 90 Gene3D G3DSA:3.30.860.10 1 90 1.1E-37 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18420 92321fad11f9fa469891fe2368d29743 90 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 24.345 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18420 92321fad11f9fa469891fe2368d29743 90 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 2 89 1.3E-43 T 28-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 MKLM6_RS18420 92321fad11f9fa469891fe2368d29743 90 PIRSF PIRSF002144 1 90 1.9E-31 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18420 92321fad11f9fa469891fe2368d29743 90 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 2.3E-22 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18420 92321fad11f9fa469891fe2368d29743 90 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 2.3E-22 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18420 92321fad11f9fa469891fe2368d29743 90 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 2.3E-22 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 Gene3D G3DSA:1.20.58.280 310 331 8.0E-9 T 28-03-2018 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 Pfam PF07719 Tetratricopeptide repeat 374 406 2.5E-5 T 28-03-2018 IPR013105 Tetratricopeptide repeat 2 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 Gene3D G3DSA:1.25.40.10 25 64 5.3E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 Gene3D G3DSA:1.25.40.10 419 456 2.6E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 Gene3D G3DSA:1.25.40.10 183 210 6.3E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 Gene3D G3DSA:1.25.40.10 380 418 1.3E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 Gene3D G3DSA:1.25.40.10 132 182 2.1E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 Pfam PF00515 Tetratricopeptide repeat 306 339 9.9E-7 T 28-03-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 Gene3D G3DSA:1.25.40.10 332 379 2.3E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 Gene3D G3DSA:1.25.40.10 259 309 3.6E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 SMART SM00028 238 271 0.34 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 SMART SM00028 204 237 1.4E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 SMART SM00028 408 441 0.034 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 SMART SM00028 306 339 3.0E-6 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 SMART SM00028 170 203 23.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 SMART SM00028 272 305 0.0055 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 SMART SM00028 20 53 110.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 SMART SM00028 54 87 0.15 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 SMART SM00028 340 373 0.022 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 SMART SM00028 374 407 1.4E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 Pfam PF14559 Tetratricopeptide repeat 65 128 4.6E-9 T 28-03-2018 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 Pfam PF14559 Tetratricopeptide repeat 216 270 6.3E-9 T 28-03-2018 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 Pfam PF13844 Glycosyl transferase family 41 493 637 4.8E-19 T 28-03-2018 IPR029489 O-GlcNAc transferase, C-terminal Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 Pfam PF13844 Glycosyl transferase family 41 656 847 5.9E-24 T 28-03-2018 IPR029489 O-GlcNAc transferase, C-terminal Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 Pfam PF07721 Tetratricopeptide repeat 412 432 0.9 T 28-03-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 Gene3D G3DSA:3.40.50.2000 639 830 1.9E-27 T 28-03-2018 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 SUPERFAMILY SSF48452 20 118 6.24E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 SUPERFAMILY SSF48452 144 448 1.71E-49 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 Gene3D G3DSA:1.25.40.10 65 131 5.6E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 Gene3D G3DSA:1.25.40.10 211 258 5.5E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 Pfam PF13181 Tetratricopeptide repeat 340 369 0.074 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18110 cd8d4a51c8b49075cfc72ecb591dd2f8 853 Pfam PF13181 Tetratricopeptide repeat 273 303 0.0054 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS00310 a7e908f94420a3f2407b1ce189bc3f92 529 SUPERFAMILY SSF52402 201 423 6.17E-56 T 28-03-2018 MKLM6_RS00310 a7e908f94420a3f2407b1ce189bc3f92 529 Pfam PF00958 GMP synthase C terminal domain 437 528 1.6E-42 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MKLM6_RS00310 a7e908f94420a3f2407b1ce189bc3f92 529 SUPERFAMILY SSF52317 11 241 5.24E-57 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS00310 a7e908f94420a3f2407b1ce189bc3f92 529 PRINTS PR00096 Glutamine amidotransferase superfamily signature 58 67 9.4E-7 T 28-03-2018 MKLM6_RS00310 a7e908f94420a3f2407b1ce189bc3f92 529 PRINTS PR00096 Glutamine amidotransferase superfamily signature 85 96 9.4E-7 T 28-03-2018 MKLM6_RS00310 a7e908f94420a3f2407b1ce189bc3f92 529 PRINTS PR00096 Glutamine amidotransferase superfamily signature 181 194 9.4E-7 T 28-03-2018 MKLM6_RS00310 a7e908f94420a3f2407b1ce189bc3f92 529 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 14 208 3.6E-75 T 28-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MKLM6_RS00310 a7e908f94420a3f2407b1ce189bc3f92 529 SUPERFAMILY SSF54810 409 529 2.48E-50 T 28-03-2018 MKLM6_RS00310 a7e908f94420a3f2407b1ce189bc3f92 529 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 11 529 55.359 T 28-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 MKLM6_RS00310 a7e908f94420a3f2407b1ce189bc3f92 529 Pfam PF02540 NAD synthase 218 306 5.8E-10 T 28-03-2018 IPR022310 NAD/GMP synthase MKLM6_RS00310 a7e908f94420a3f2407b1ce189bc3f92 529 Gene3D G3DSA:3.30.300.10 405 529 4.5E-52 T 28-03-2018 MKLM6_RS00310 a7e908f94420a3f2407b1ce189bc3f92 529 PRINTS PR00097 Anthranilate synthase component II signature 181 194 1.8E-5 T 28-03-2018 MKLM6_RS00310 a7e908f94420a3f2407b1ce189bc3f92 529 PRINTS PR00097 Anthranilate synthase component II signature 85 96 1.8E-5 T 28-03-2018 MKLM6_RS00310 a7e908f94420a3f2407b1ce189bc3f92 529 PRINTS PR00097 Anthranilate synthase component II signature 58 67 1.8E-5 T 28-03-2018 MKLM6_RS00310 a7e908f94420a3f2407b1ce189bc3f92 529 Pfam PF00117 Glutamine amidotransferase class-I 16 204 6.8E-41 T 28-03-2018 IPR017926 Glutamine amidotransferase MKLM6_RS00310 a7e908f94420a3f2407b1ce189bc3f92 529 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 216 529 5.4E-149 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MKLM6_RS00310 a7e908f94420a3f2407b1ce189bc3f92 529 Gene3D G3DSA:3.40.50.880 9 224 7.2E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS00310 a7e908f94420a3f2407b1ce189bc3f92 529 Gene3D G3DSA:3.40.50.620 225 404 1.1E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS03725 9d6584c9f8902cab391fdba15fb769df 468 Gene3D G3DSA:3.30.499.10 305 467 2.2E-47 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 MKLM6_RS03725 9d6584c9f8902cab391fdba15fb769df 468 Gene3D G3DSA:3.40.1060.10 155 289 2.9E-42 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 MKLM6_RS03725 9d6584c9f8902cab391fdba15fb769df 468 SUPERFAMILY SSF53732 2 465 3.79E-160 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MKLM6_RS03725 9d6584c9f8902cab391fdba15fb769df 468 Gene3D G3DSA:3.30.499.10 1 154 9.5E-39 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 MKLM6_RS03725 9d6584c9f8902cab391fdba15fb769df 468 PRINTS PR00415 Aconitase family signature 83 96 1.5E-46 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MKLM6_RS03725 9d6584c9f8902cab391fdba15fb769df 468 PRINTS PR00415 Aconitase family signature 109 117 1.5E-46 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MKLM6_RS03725 9d6584c9f8902cab391fdba15fb769df 468 PRINTS PR00415 Aconitase family signature 196 209 1.5E-46 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MKLM6_RS03725 9d6584c9f8902cab391fdba15fb769df 468 PRINTS PR00415 Aconitase family signature 344 355 1.5E-46 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MKLM6_RS03725 9d6584c9f8902cab391fdba15fb769df 468 PRINTS PR00415 Aconitase family signature 120 133 1.5E-46 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MKLM6_RS03725 9d6584c9f8902cab391fdba15fb769df 468 PRINTS PR00415 Aconitase family signature 134 149 1.5E-46 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MKLM6_RS03725 9d6584c9f8902cab391fdba15fb769df 468 PRINTS PR00415 Aconitase family signature 287 301 1.5E-46 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MKLM6_RS03725 9d6584c9f8902cab391fdba15fb769df 468 PRINTS PR00415 Aconitase family signature 210 223 1.5E-46 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MKLM6_RS03725 9d6584c9f8902cab391fdba15fb769df 468 PRINTS PR00415 Aconitase family signature 401 414 1.5E-46 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MKLM6_RS03725 9d6584c9f8902cab391fdba15fb769df 468 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 468 59.363 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 MKLM6_RS03725 9d6584c9f8902cab391fdba15fb769df 468 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 3 465 5.1E-236 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 MKLM6_RS03725 9d6584c9f8902cab391fdba15fb769df 468 ProSitePatterns PS00450 Aconitase family signature 1. 340 356 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MKLM6_RS03725 9d6584c9f8902cab391fdba15fb769df 468 Pfam PF00330 Aconitase family (aconitate hydratase) 8 459 6.3E-153 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MKLM6_RS07365 358e4fc0a98b407f59e473486be31220 425 SUPERFAMILY SSF52540 2 186 2.66E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS07365 358e4fc0a98b407f59e473486be31220 425 Gene3D G3DSA:3.40.50.880 229 361 4.2E-19 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS07365 358e4fc0a98b407f59e473486be31220 425 Gene3D G3DSA:3.40.50.300 1 44 7.5E-6 T 28-03-2018 MKLM6_RS07365 358e4fc0a98b407f59e473486be31220 425 Gene3D G3DSA:3.40.50.300 47 180 3.7E-20 T 28-03-2018 MKLM6_RS07365 358e4fc0a98b407f59e473486be31220 425 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 2 171 2.6E-13 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain MKLM6_RS07365 358e4fc0a98b407f59e473486be31220 425 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 231 409 1.5E-33 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 MKLM6_RS07365 358e4fc0a98b407f59e473486be31220 425 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 2 422 1.8E-84 T 28-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 MKLM6_RS07365 358e4fc0a98b407f59e473486be31220 425 SUPERFAMILY SSF52317 229 421 5.73E-27 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 Pfam PF00512 His Kinase A (phospho-acceptor) domain 390 455 3.7E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 SMART SM00448 637 748 7.3E-13 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 PRINTS PR00344 Bacterial sensor protein C-terminal signature 555 565 5.6E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 PRINTS PR00344 Bacterial sensor protein C-terminal signature 537 551 5.6E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 PRINTS PR00344 Bacterial sensor protein C-terminal signature 572 590 5.6E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 PRINTS PR00344 Bacterial sensor protein C-terminal signature 596 609 5.6E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 Pfam PF00989 PAS fold 10 78 6.4E-9 T 28-03-2018 IPR013767 PAS fold GO:0006355 MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 SUPERFAMILY SSF55874 444 613 9.3E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 SUPERFAMILY SSF52172 636 750 1.57E-19 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 SMART SM00091 131 197 1.4E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 SMART SM00091 7 74 3.6E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 SMART SM00091 257 324 2.6 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 Pfam PF00072 Response regulator receiver domain 639 748 3.8E-13 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 Gene3D G3DSA:3.40.50.2300 632 752 1.5E-17 T 28-03-2018 MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 SUPERFAMILY SSF55785 117 243 1.38E-23 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 SMART SM00388 390 455 4.1E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 Gene3D G3DSA:1.10.287.130 390 451 1.8E-16 T 28-03-2018 MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 Gene3D G3DSA:3.30.450.20 2 125 8.1E-20 T 28-03-2018 MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 SMART SM00086 329 370 0.024 T 28-03-2018 IPR001610 PAC motif MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 SMART SM00086 80 119 280.0 T 28-03-2018 IPR001610 PAC motif MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 SMART SM00086 203 245 0.0045 T 28-03-2018 IPR001610 PAC motif MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 SUPERFAMILY SSF55785 19 128 1.53E-14 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 Gene3D G3DSA:3.30.565.10 460 621 6.3E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 11 125 1.7E-14 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 254 377 1.9E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 127 250 2.6E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 Pfam PF08447 PAS fold 280 364 5.9E-11 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 Pfam PF08447 PAS fold 154 238 2.7E-11 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 SUPERFAMILY SSF47384 376 456 1.49E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 502 610 2.2E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 SUPERFAMILY SSF55785 242 368 2.09E-14 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 Gene3D G3DSA:3.30.450.20 251 389 6.3E-30 T 28-03-2018 MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 SMART SM00387 501 612 9.6E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS03630 c04e2dc2688bea9b94ac1f094bd26b97 753 Gene3D G3DSA:3.30.450.20 126 250 2.7E-28 T 28-03-2018 MKLM6_RS21640 acba23e91c6014e00b174eea804a0119 73 Pfam PF02416 mttA/Hcf106 family 4 49 3.7E-15 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 MKLM6_RS21640 acba23e91c6014e00b174eea804a0119 73 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 69 20.675 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 MKLM6_RS21640 acba23e91c6014e00b174eea804a0119 73 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 2 46 7.8E-21 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 MKLM6_RS06060 722815e33b9d7ae52092dba83d320a97 191 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 14 169 23.75 T 28-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 MKLM6_RS06060 722815e33b9d7ae52092dba83d320a97 191 Pfam PF03975 CheD chemotactic sensory transduction 78 165 2.6E-23 T 28-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 MKLM6_RS06060 722815e33b9d7ae52092dba83d320a97 191 SUPERFAMILY SSF64438 21 168 2.47E-38 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic MKLM6_RS19115 c3b6e45a18e974fcd6e47e72f779b3ab 229 SUPERFAMILY SSF56281 1 225 9.38E-53 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS19115 c3b6e45a18e974fcd6e47e72f779b3ab 229 SMART SM00849 12 171 9.9E-26 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS19115 c3b6e45a18e974fcd6e47e72f779b3ab 229 Gene3D G3DSA:3.60.15.10 1 229 5.7E-46 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS19115 c3b6e45a18e974fcd6e47e72f779b3ab 229 Pfam PF00753 Metallo-beta-lactamase superfamily 11 171 2.2E-16 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS08920 e90e8ca8cb7d97f44fdacac20a3b84c0 1405 SUPERFAMILY SSF52540 1157 1396 2.0E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS08920 e90e8ca8cb7d97f44fdacac20a3b84c0 1405 SUPERFAMILY SSF52540 930 1156 1.3E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS08920 e90e8ca8cb7d97f44fdacac20a3b84c0 1405 Pfam PF00176 SNF2 family N-terminal domain 948 1227 7.5E-52 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 MKLM6_RS08920 e90e8ca8cb7d97f44fdacac20a3b84c0 1405 SMART SM00490 1266 1348 1.2E-24 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS08920 e90e8ca8cb7d97f44fdacac20a3b84c0 1405 Gene3D G3DSA:3.40.50.10810 951 1157 2.3E-47 T 28-03-2018 MKLM6_RS08920 e90e8ca8cb7d97f44fdacac20a3b84c0 1405 Gene3D G3DSA:1.25.40.10 95 950 1.4E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS08920 e90e8ca8cb7d97f44fdacac20a3b84c0 1405 SMART SM00487 943 1125 4.8E-25 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MKLM6_RS08920 e90e8ca8cb7d97f44fdacac20a3b84c0 1405 Pfam PF00271 Helicase conserved C-terminal domain 1243 1348 1.9E-20 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS08920 e90e8ca8cb7d97f44fdacac20a3b84c0 1405 Gene3D G3DSA:3.40.50.300 1228 1386 2.8E-37 T 28-03-2018 MKLM6_RS01440 509d40a662feea6d5afd237a0645899a 305 Pfam PF03186 CobD/Cbib protein 8 284 1.3E-92 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 MKLM6_RS01440 509d40a662feea6d5afd237a0645899a 305 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 5 270 8.7E-61 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 MKLM6_RS01440 509d40a662feea6d5afd237a0645899a 305 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 305 96.223 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 MKLM6_RS09185 b4dd10c53a31c30064d3f33f79ed1440 398 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 26 366 3.5E-119 T 28-03-2018 IPR030931 Group II intron reverse transcriptase/maturase MKLM6_RS09185 b4dd10c53a31c30064d3f33f79ed1440 398 Pfam PF08388 Group II intron, maturase-specific domain 304 374 5.6E-16 T 28-03-2018 IPR013597 Group II intron, maturase-specific MKLM6_RS09185 b4dd10c53a31c30064d3f33f79ed1440 398 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 81 291 5.5E-42 T 28-03-2018 IPR000477 Reverse transcriptase domain MKLM6_RS09185 b4dd10c53a31c30064d3f33f79ed1440 398 Gene3D G3DSA:3.30.70.270 116 291 2.3E-32 T 28-03-2018 MKLM6_RS09185 b4dd10c53a31c30064d3f33f79ed1440 398 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 144 162 1.1E-5 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MKLM6_RS09185 b4dd10c53a31c30064d3f33f79ed1440 398 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 220 233 1.1E-5 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MKLM6_RS09185 b4dd10c53a31c30064d3f33f79ed1440 398 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 202 215 1.1E-5 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MKLM6_RS09185 b4dd10c53a31c30064d3f33f79ed1440 398 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 76 89 1.1E-5 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MKLM6_RS09185 b4dd10c53a31c30064d3f33f79ed1440 398 SUPERFAMILY SSF56672 31 360 1.45E-47 T 28-03-2018 MKLM6_RS16595 9e71915400ae546b65d362fd2cbb7d2c 109 Pfam PF00313 'Cold-shock' DNA-binding domain 8 67 1.6E-11 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MKLM6_RS16595 9e71915400ae546b65d362fd2cbb7d2c 109 SMART SM00357 8 72 5.0E-11 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 MKLM6_RS16595 9e71915400ae546b65d362fd2cbb7d2c 109 ProSitePatterns PS00352 'Cold-shock' domain signature. 20 39 - T 28-03-2018 IPR019844 Cold-shock conserved site MKLM6_RS16595 9e71915400ae546b65d362fd2cbb7d2c 109 SUPERFAMILY SSF50249 5 71 5.9E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS16595 9e71915400ae546b65d362fd2cbb7d2c 109 Gene3D G3DSA:2.40.50.140 1 87 9.5E-17 T 28-03-2018 MKLM6_RS19810 fa8b75c8b0afef950744ce75c536336f 607 SUPERFAMILY SSF51230 531 606 1.09E-20 T 28-03-2018 IPR011053 Single hybrid motif MKLM6_RS19810 fa8b75c8b0afef950744ce75c536336f 607 Pfam PF02436 Conserved carboxylase domain 292 480 2.3E-55 T 28-03-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 MKLM6_RS19810 fa8b75c8b0afef950744ce75c536336f 607 Gene3D G3DSA:1.10.10.60 398 443 2.8E-13 T 28-03-2018 MKLM6_RS19810 fa8b75c8b0afef950744ce75c536336f 607 SUPERFAMILY SSF89000 296 449 9.42E-51 T 28-03-2018 MKLM6_RS19810 fa8b75c8b0afef950744ce75c536336f 607 TIGRFAM TIGR01108 oadA: oxaloacetate decarboxylase alpha subunit 6 603 6.8E-257 T 28-03-2018 IPR005776 Oxaloacetate decarboxylase, alpha subunit GO:0006814|GO:0008948 MKLM6_RS19810 fa8b75c8b0afef950744ce75c536336f 607 Gene3D G3DSA:3.20.20.70 1 283 3.4E-76 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS19810 fa8b75c8b0afef950744ce75c536336f 607 Gene3D G3DSA:2.40.50.100 529 607 6.0E-20 T 28-03-2018 MKLM6_RS19810 fa8b75c8b0afef950744ce75c536336f 607 Pfam PF00364 Biotin-requiring enzyme 539 606 1.9E-17 T 28-03-2018 IPR000089 Biotin/lipoyl attachment MKLM6_RS19810 fa8b75c8b0afef950744ce75c536336f 607 Pfam PF00682 HMGL-like 3 269 6.3E-51 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MKLM6_RS19810 fa8b75c8b0afef950744ce75c536336f 607 SUPERFAMILY SSF51569 1 288 3.85E-89 T 28-03-2018 MKLM6_RS10105 f27c49c4c659ea62a2b7a476694ed385 120 Pfam PF00072 Response regulator receiver domain 4 115 2.2E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS10105 f27c49c4c659ea62a2b7a476694ed385 120 Gene3D G3DSA:3.40.50.2300 2 120 8.3E-36 T 28-03-2018 MKLM6_RS10105 f27c49c4c659ea62a2b7a476694ed385 120 SMART SM00448 2 115 2.4E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS10105 f27c49c4c659ea62a2b7a476694ed385 120 SUPERFAMILY SSF52172 3 119 1.71E-36 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS07960 9f04e0e6510277b8dd15c0aa56eb785f 157 Gene3D G3DSA:3.10.20.30 1 75 2.7E-25 T 28-03-2018 IPR012675 Beta-grasp domain MKLM6_RS07960 9f04e0e6510277b8dd15c0aa56eb785f 157 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MKLM6_RS07960 9f04e0e6510277b8dd15c0aa56eb785f 157 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 64 3.5E-7 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MKLM6_RS07960 9f04e0e6510277b8dd15c0aa56eb785f 157 Gene3D G3DSA:1.10.150.120 76 156 6.0E-28 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 MKLM6_RS07960 9f04e0e6510277b8dd15c0aa56eb785f 157 SUPERFAMILY SSF54292 3 79 1.44E-25 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MKLM6_RS07960 9f04e0e6510277b8dd15c0aa56eb785f 157 Pfam PF01799 [2Fe-2S] binding domain 74 145 1.7E-26 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 MKLM6_RS07960 9f04e0e6510277b8dd15c0aa56eb785f 157 SUPERFAMILY SSF47741 74 151 1.83E-30 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 SMART SM00086 219 260 20.0 T 28-03-2018 IPR001610 PAC motif MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 SMART SM00086 471 514 0.97 T 28-03-2018 IPR001610 PAC motif MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 SMART SM00086 343 386 4.8 T 28-03-2018 IPR001610 PAC motif MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 SMART SM00086 598 639 0.079 T 28-03-2018 IPR001610 PAC motif MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 SUPERFAMILY SSF55785 383 512 1.74E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 Pfam PF08447 PAS fold 549 632 9.1E-11 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 Pfam PF08447 PAS fold 422 508 6.6E-11 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 Pfam PF07730 Histidine kinase 667 732 4.2E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 Pfam PF08448 PAS fold 279 387 3.5E-17 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 Pfam PF08448 PAS fold 154 262 1.9E-19 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 SMART SM00387 771 865 5.2E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 SUPERFAMILY SSF55785 17 123 2.79E-6 T 28-03-2018 IPR000014 PAS domain MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 Pfam PF13188 PAS domain 19 52 8.9E-4 T 28-03-2018 IPR000014 PAS domain MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 Gene3D G3DSA:3.30.450.20 270 396 8.0E-22 T 28-03-2018 MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 Gene3D G3DSA:3.30.450.20 136 269 1.8E-21 T 28-03-2018 MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 SUPERFAMILY SSF55785 257 384 1.59E-19 T 28-03-2018 IPR000014 PAS domain MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 SMART SM00091 16 82 0.011 T 28-03-2018 IPR000014 PAS domain MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 SMART SM00091 272 339 0.064 T 28-03-2018 IPR000014 PAS domain MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 SMART SM00091 398 465 0.0018 T 28-03-2018 IPR000014 PAS domain MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 SMART SM00091 148 214 0.008 T 28-03-2018 IPR000014 PAS domain MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 SMART SM00091 526 593 0.11 T 28-03-2018 IPR000014 PAS domain MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 Gene3D G3DSA:3.30.565.10 665 864 1.3E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 SUPERFAMILY SSF55785 153 263 6.81E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 Gene3D G3DSA:3.30.450.20 8 126 1.1E-8 T 28-03-2018 MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 Gene3D G3DSA:3.30.450.20 524 664 7.2E-25 T 28-03-2018 MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 Gene3D G3DSA:3.30.450.20 397 523 1.3E-19 T 28-03-2018 MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 SUPERFAMILY SSF55874 749 862 3.01E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 397 521 1.0E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 150 266 4.4E-13 T 28-03-2018 IPR000014 PAS domain MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 269 393 1.9E-14 T 28-03-2018 IPR000014 PAS domain MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 522 646 8.6E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS00895 5c9005ef487ffe4cfd298b4223a09d23 870 SUPERFAMILY SSF55785 511 637 1.31E-17 T 28-03-2018 IPR000014 PAS domain MKLM6_RS06025 3708afe27ce29e4670a2a9be2852675e 596 SUPERFAMILY SSF52540 287 522 5.93E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS06025 3708afe27ce29e4670a2a9be2852675e 596 Pfam PF08448 PAS fold 148 256 1.3E-9 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS06025 3708afe27ce29e4670a2a9be2852675e 596 SMART SM00382 308 455 3.9E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS06025 3708afe27ce29e4670a2a9be2852675e 596 SMART SM00448 11 124 4.0E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS06025 3708afe27ce29e4670a2a9be2852675e 596 Gene3D G3DSA:1.10.10.60 551 589 5.4E-13 T 28-03-2018 MKLM6_RS06025 3708afe27ce29e4670a2a9be2852675e 596 SUPERFAMILY SSF55785 131 252 2.97E-19 T 28-03-2018 IPR000014 PAS domain MKLM6_RS06025 3708afe27ce29e4670a2a9be2852675e 596 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 312 325 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MKLM6_RS06025 3708afe27ce29e4670a2a9be2852675e 596 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 374 389 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MKLM6_RS06025 3708afe27ce29e4670a2a9be2852675e 596 Gene3D G3DSA:3.40.50.2300 1 137 1.5E-38 T 28-03-2018 MKLM6_RS06025 3708afe27ce29e4670a2a9be2852675e 596 SUPERFAMILY SSF46689 501 592 1.47E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS06025 3708afe27ce29e4670a2a9be2852675e 596 Pfam PF00072 Response regulator receiver domain 13 124 7.6E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS06025 3708afe27ce29e4670a2a9be2852675e 596 Gene3D G3DSA:3.30.450.20 138 267 1.0E-22 T 28-03-2018 MKLM6_RS06025 3708afe27ce29e4670a2a9be2852675e 596 Pfam PF02954 Bacterial regulatory protein, Fis family 546 590 1.6E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS06025 3708afe27ce29e4670a2a9be2852675e 596 SUPERFAMILY SSF52172 9 144 2.28E-41 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS06025 3708afe27ce29e4670a2a9be2852675e 596 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 501 510 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site MKLM6_RS06025 3708afe27ce29e4670a2a9be2852675e 596 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 138 261 3.8E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS06025 3708afe27ce29e4670a2a9be2852675e 596 Gene3D G3DSA:1.10.8.60 461 550 1.4E-24 T 28-03-2018 MKLM6_RS06025 3708afe27ce29e4670a2a9be2852675e 596 Gene3D G3DSA:3.40.50.300 283 460 2.1E-31 T 28-03-2018 MKLM6_RS06025 3708afe27ce29e4670a2a9be2852675e 596 Pfam PF00158 Sigma-54 interaction domain 288 455 4.3E-72 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MKLM6_RS06025 3708afe27ce29e4670a2a9be2852675e 596 SMART SM00091 142 208 1.8E-6 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10510 f22862f85cd40e1890736b89dea7589d 290 SUPERFAMILY SSF161098 21 273 3.4E-55 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MKLM6_RS10510 f22862f85cd40e1890736b89dea7589d 290 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 23 282 1.2E-121 T 28-03-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 MKLM6_RS10510 f22862f85cd40e1890736b89dea7589d 290 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 22 279 3.0E-99 T 28-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 MKLM6_RS10510 f22862f85cd40e1890736b89dea7589d 290 Gene3D G3DSA:1.10.3720.10 23 288 1.1E-42 T 28-03-2018 MKLM6_RS10510 f22862f85cd40e1890736b89dea7589d 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 278 9.1E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MKLM6_RS15725 75c2041edd65ef46cadd2d084897d1f8 651 Gene3D G3DSA:3.60.20.10 1 230 4.1E-53 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MKLM6_RS15725 75c2041edd65ef46cadd2d084897d1f8 651 Pfam PF00733 Asparagine synthase 257 648 1.8E-113 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 MKLM6_RS15725 75c2041edd65ef46cadd2d084897d1f8 651 Pfam PF13537 Glutamine amidotransferase domain 48 170 3.1E-43 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain MKLM6_RS15725 75c2041edd65ef46cadd2d084897d1f8 651 Gene3D G3DSA:3.40.50.620 231 651 7.8E-80 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS15725 75c2041edd65ef46cadd2d084897d1f8 651 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 584 2.2E-135 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MKLM6_RS15725 75c2041edd65ef46cadd2d084897d1f8 651 SUPERFAMILY SSF52402 504 644 2.56E-91 T 28-03-2018 MKLM6_RS15725 75c2041edd65ef46cadd2d084897d1f8 651 SUPERFAMILY SSF52402 248 401 2.56E-91 T 28-03-2018 MKLM6_RS15725 75c2041edd65ef46cadd2d084897d1f8 651 SUPERFAMILY SSF56235 1 221 7.55E-60 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MKLM6_RS15725 75c2041edd65ef46cadd2d084897d1f8 651 PIRSF PIRSF001589 1 651 3.7E-153 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MKLM6_RS02190 a47ffe6c8359513c71f67a3b03559d86 443 SMART SM00490 267 348 5.1E-33 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS02190 a47ffe6c8359513c71f67a3b03559d86 443 Pfam PF00270 DEAD/DEAH box helicase 33 204 4.5E-46 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MKLM6_RS02190 a47ffe6c8359513c71f67a3b03559d86 443 SMART SM00487 28 231 4.6E-55 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MKLM6_RS02190 a47ffe6c8359513c71f67a3b03559d86 443 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 160 168 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MKLM6_RS02190 a47ffe6c8359513c71f67a3b03559d86 443 Gene3D G3DSA:3.40.50.300 2 233 1.0E-49 T 28-03-2018 MKLM6_RS02190 a47ffe6c8359513c71f67a3b03559d86 443 SUPERFAMILY SSF52540 80 360 3.03E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS02190 a47ffe6c8359513c71f67a3b03559d86 443 Gene3D G3DSA:3.40.50.300 234 437 9.2E-46 T 28-03-2018 MKLM6_RS02190 a47ffe6c8359513c71f67a3b03559d86 443 Pfam PF00271 Helicase conserved C-terminal domain 240 348 2.1E-30 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS02190 a47ffe6c8359513c71f67a3b03559d86 443 Hamap MF_00661 ATP-dependent RNA helicase RhlB [rhlB]. 8 386 51.788 T 28-03-2018 IPR023554 ATP-dependent RNA helicase RhlB type GO:0004004 MKLM6_RS19380 3513dbb8ef223a619763d0a4f0f881e1 127 Pfam PF01597 Glycine cleavage H-protein 9 126 1.8E-41 T 28-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate MKLM6_RS19380 3513dbb8ef223a619763d0a4f0f881e1 127 SUPERFAMILY SSF51230 5 126 3.8E-39 T 28-03-2018 IPR011053 Single hybrid motif MKLM6_RS19380 3513dbb8ef223a619763d0a4f0f881e1 127 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MKLM6_RS19380 3513dbb8ef223a619763d0a4f0f881e1 127 Gene3D G3DSA:2.40.50.100 6 127 2.0E-42 T 28-03-2018 MKLM6_RS19380 3513dbb8ef223a619763d0a4f0f881e1 127 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 4 126 3.6E-44 T 28-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 MKLM6_RS19380 3513dbb8ef223a619763d0a4f0f881e1 127 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 126 37.916 T 28-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 MKLM6_RS13435 f755f590cbf68bf8e96eafa860f6795e 377 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 198 366 4.3E-54 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS13435 f755f590cbf68bf8e96eafa860f6795e 377 Gene3D G3DSA:3.30.70.270 196 367 3.4E-56 T 28-03-2018 MKLM6_RS13435 f755f590cbf68bf8e96eafa860f6795e 377 SUPERFAMILY SSF55781 34 198 7.2E-12 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS13435 f755f590cbf68bf8e96eafa860f6795e 377 Gene3D G3DSA:3.30.450.40 1 195 8.0E-13 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS13435 f755f590cbf68bf8e96eafa860f6795e 377 Pfam PF04340 Protein of unknown function, DUF484 13 188 4.1E-9 T 28-03-2018 IPR007435 Protein of unknown function DUF484 MKLM6_RS13435 f755f590cbf68bf8e96eafa860f6795e 377 SUPERFAMILY SSF55073 205 365 1.1E-46 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS13435 f755f590cbf68bf8e96eafa860f6795e 377 Pfam PF00990 Diguanylate cyclase, GGDEF domain 201 364 7.5E-49 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS13435 f755f590cbf68bf8e96eafa860f6795e 377 SMART SM00267 189 368 6.9E-59 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS21695 3d28148a3a287af2e495b88ab725f322 1042 Gene3D G3DSA:3.30.70.1430 44 148 1.2E-30 T 28-03-2018 MKLM6_RS21695 3d28148a3a287af2e495b88ab725f322 1042 Gene3D G3DSA:1.20.1640.10 828 1033 1.4E-30 T 28-03-2018 MKLM6_RS21695 3d28148a3a287af2e495b88ab725f322 1042 Gene3D G3DSA:3.30.70.1430 577 685 3.3E-9 T 28-03-2018 MKLM6_RS21695 3d28148a3a287af2e495b88ab725f322 1042 SUPERFAMILY SSF82866 811 1033 7.32E-42 T 28-03-2018 MKLM6_RS21695 3d28148a3a287af2e495b88ab725f322 1042 SUPERFAMILY SSF82693 140 186 4.53E-15 T 28-03-2018 MKLM6_RS21695 3d28148a3a287af2e495b88ab725f322 1042 SUPERFAMILY SSF82693 272 324 4.53E-15 T 28-03-2018 MKLM6_RS21695 3d28148a3a287af2e495b88ab725f322 1042 PRINTS PR00702 Acriflavin resistance protein family signature 466 489 1.9E-25 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS21695 3d28148a3a287af2e495b88ab725f322 1042 PRINTS PR00702 Acriflavin resistance protein family signature 360 381 1.9E-25 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS21695 3d28148a3a287af2e495b88ab725f322 1042 PRINTS PR00702 Acriflavin resistance protein family signature 441 464 1.9E-25 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS21695 3d28148a3a287af2e495b88ab725f322 1042 PRINTS PR00702 Acriflavin resistance protein family signature 14 38 1.9E-25 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS21695 3d28148a3a287af2e495b88ab725f322 1042 PRINTS PR00702 Acriflavin resistance protein family signature 42 60 1.9E-25 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS21695 3d28148a3a287af2e495b88ab725f322 1042 PRINTS PR00702 Acriflavin resistance protein family signature 388 412 1.9E-25 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS21695 3d28148a3a287af2e495b88ab725f322 1042 SUPERFAMILY SSF82693 44 139 5.58E-20 T 28-03-2018 MKLM6_RS21695 3d28148a3a287af2e495b88ab725f322 1042 SUPERFAMILY SSF82714 189 270 9.94E-11 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS21695 3d28148a3a287af2e495b88ab725f322 1042 Gene3D G3DSA:1.20.1640.10 287 506 1.8E-34 T 28-03-2018 MKLM6_RS21695 3d28148a3a287af2e495b88ab725f322 1042 SUPERFAMILY SSF82866 302 492 2.22E-35 T 28-03-2018 MKLM6_RS21695 3d28148a3a287af2e495b88ab725f322 1042 SUPERFAMILY SSF82714 729 815 5.62E-16 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS21695 3d28148a3a287af2e495b88ab725f322 1042 Pfam PF00873 AcrB/AcrD/AcrF family 8 1028 6.4E-162 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS21695 3d28148a3a287af2e495b88ab725f322 1042 Gene3D G3DSA:3.30.2090.10 185 271 6.6E-13 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS21695 3d28148a3a287af2e495b88ab725f322 1042 Gene3D G3DSA:3.30.2090.10 727 816 2.5E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS10685 2af55821c8cbbc4e590be8b48f0a8cb6 491 Gene3D G3DSA:3.40.50.20 173 286 1.9E-21 T 28-03-2018 MKLM6_RS10685 2af55821c8cbbc4e590be8b48f0a8cb6 491 Pfam PF08443 RimK-like ATP-grasp domain 283 460 6.0E-7 T 28-03-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 MKLM6_RS10685 2af55821c8cbbc4e590be8b48f0a8cb6 491 Pfam PF14401 RimK-like ATPgrasp N-terminal domain 27 174 6.2E-49 T 28-03-2018 IPR025839 RimK-like ATPgrasp N-terminal domain MKLM6_RS10685 2af55821c8cbbc4e590be8b48f0a8cb6 491 SUPERFAMILY SSF56059 274 482 2.83E-41 T 28-03-2018 MKLM6_RS10685 2af55821c8cbbc4e590be8b48f0a8cb6 491 Gene3D G3DSA:3.30.470.20 357 466 1.1E-20 T 28-03-2018 MKLM6_RS10685 2af55821c8cbbc4e590be8b48f0a8cb6 491 Gene3D G3DSA:3.30.1490.20 287 356 2.9E-12 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MKLM6_RS15375 1fb9eae085b0e2b47843f09ca10b5911 374 SUPERFAMILY SSF53756 2 370 2.88E-108 T 28-03-2018 MKLM6_RS15375 1fb9eae085b0e2b47843f09ca10b5911 374 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 5 369 3.7E-97 T 28-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 MKLM6_RS15375 1fb9eae085b0e2b47843f09ca10b5911 374 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 34 366 7.5E-107 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 MKLM6_RS15375 1fb9eae085b0e2b47843f09ca10b5911 374 Gene3D G3DSA:3.40.50.2000 211 346 5.4E-34 T 28-03-2018 MKLM6_RS15375 1fb9eae085b0e2b47843f09ca10b5911 374 Gene3D G3DSA:3.40.50.2000 1 210 5.3E-79 T 28-03-2018 MKLM6_RS13815 173a660d159f28c8c7d8f17c16fa478a 421 Gene3D G3DSA:3.40.50.300 165 225 1.2E-13 T 28-03-2018 MKLM6_RS13815 173a660d159f28c8c7d8f17c16fa478a 421 PIRSF PIRSF006809 3 415 9.6E-139 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 MKLM6_RS13815 173a660d159f28c8c7d8f17c16fa478a 421 Hamap MF_00900 GTPase HflX [hflX]. 25 388 46.413 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 MKLM6_RS13815 173a660d159f28c8c7d8f17c16fa478a 421 Pfam PF01926 50S ribosome-binding GTPase 198 316 2.5E-19 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS13815 173a660d159f28c8c7d8f17c16fa478a 421 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 10 357 8.2E-151 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 MKLM6_RS13815 173a660d159f28c8c7d8f17c16fa478a 421 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 219 237 4.3E-10 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS13815 173a660d159f28c8c7d8f17c16fa478a 421 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 265 283 4.3E-10 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS13815 173a660d159f28c8c7d8f17c16fa478a 421 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 198 218 4.3E-10 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS13815 173a660d159f28c8c7d8f17c16fa478a 421 Pfam PF16360 GTP-binding GTPase Middle Region 112 190 6.5E-29 T 28-03-2018 IPR032305 GTP-binding protein, middle domain MKLM6_RS13815 173a660d159f28c8c7d8f17c16fa478a 421 SUPERFAMILY SSF52540 195 364 9.11E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS13815 173a660d159f28c8c7d8f17c16fa478a 421 Pfam PF13167 GTP-binding GTPase N-terminal 23 110 6.9E-31 T 28-03-2018 IPR025121 GTPase HflX, N-terminal MKLM6_RS13815 173a660d159f28c8c7d8f17c16fa478a 421 Gene3D G3DSA:3.40.50.300 226 372 1.9E-16 T 28-03-2018 MKLM6_RS05140 8ea89ff08feb9eafb4cc4a06ed535ba2 189 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 123 186 1.3E-9 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS05140 8ea89ff08feb9eafb4cc4a06ed535ba2 189 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 28 97 8.1E-7 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS05140 8ea89ff08feb9eafb4cc4a06ed535ba2 189 Gene3D G3DSA:1.10.760.10 105 189 1.5E-21 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS05140 8ea89ff08feb9eafb4cc4a06ed535ba2 189 Gene3D G3DSA:1.10.760.10 16 101 6.0E-19 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS05140 8ea89ff08feb9eafb4cc4a06ed535ba2 189 SUPERFAMILY SSF46626 22 101 3.51E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS05140 8ea89ff08feb9eafb4cc4a06ed535ba2 189 SUPERFAMILY SSF46626 111 188 8.17E-21 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS13400 81af86b75339fb3aad550752745d9c3f 277 SMART SM00481 6 71 3.8E-22 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal MKLM6_RS13400 81af86b75339fb3aad550752745d9c3f 277 Pfam PF02811 PHP domain 7 125 1.5E-10 T 28-03-2018 IPR004013 PHP domain GO:0003824 MKLM6_RS13400 81af86b75339fb3aad550752745d9c3f 277 Gene3D G3DSA:3.20.20.140 5 268 4.1E-46 T 28-03-2018 MKLM6_RS13400 81af86b75339fb3aad550752745d9c3f 277 SUPERFAMILY SSF89550 166 276 8.44E-51 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MKLM6_RS13400 81af86b75339fb3aad550752745d9c3f 277 SUPERFAMILY SSF89550 3 84 8.44E-51 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MKLM6_RS16915 7b09f8bab7ccb17701ab2a3bd0851590 257 Pfam PF03502 Nucleoside-specific channel-forming protein, Tsx 83 242 2.6E-10 T 28-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 MKLM6_RS16915 7b09f8bab7ccb17701ab2a3bd0851590 257 SUPERFAMILY SSF111364 27 257 3.14E-46 T 28-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 MKLM6_RS16915 7b09f8bab7ccb17701ab2a3bd0851590 257 Gene3D G3DSA:2.40.230.20 21 251 3.8E-58 T 28-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 MKLM6_RS02865 afa4aaf4ed993f42deb5e0b718d44566 242 SUPERFAMILY SSF48613 6 239 3.71E-73 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MKLM6_RS02865 afa4aaf4ed993f42deb5e0b718d44566 242 Hamap MF_00654 Pyrroloquinoline-quinone synthase [pqqC]. 1 242 125.898 T 28-03-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 MKLM6_RS02865 afa4aaf4ed993f42deb5e0b718d44566 242 Gene3D G3DSA:1.20.910.10 2 242 4.1E-36 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MKLM6_RS02865 afa4aaf4ed993f42deb5e0b718d44566 242 Pfam PF03070 TENA/THI-4/PQQC family 15 224 1.3E-55 T 28-03-2018 IPR004305 Thiaminase-2/PQQC MKLM6_RS02865 afa4aaf4ed993f42deb5e0b718d44566 242 TIGRFAM TIGR02111 PQQ_syn_pqqC: coenzyme PQQ biosynthesis protein C 9 237 9.8E-109 T 28-03-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 MKLM6_RS09390 0927e78a4c4d4a6d5b51c028e59aab36 401 TIGRFAM TIGR03863 PQQ_ABC_bind: ABC transporter, substrate binding protein, PQQ-dependent alcohol dehydrogenase system 60 401 4.0E-144 T 28-03-2018 IPR022478 ABC transporter, substrate-binding protein, PQQ-dependent alcohol dehydrogenase system MKLM6_RS09390 0927e78a4c4d4a6d5b51c028e59aab36 401 Gene3D G3DSA:3.40.50.2300 237 363 4.8E-4 T 28-03-2018 MKLM6_RS09390 0927e78a4c4d4a6d5b51c028e59aab36 401 Gene3D G3DSA:3.40.50.2300 13 236 1.4E-6 T 28-03-2018 MKLM6_RS09390 0927e78a4c4d4a6d5b51c028e59aab36 401 SUPERFAMILY SSF53822 64 366 2.77E-20 T 28-03-2018 IPR028082 Periplasmic binding protein-like I MKLM6_RS04940 463ed2f980dba92568a675692f4ad7f6 284 PRINTS PR00169 Potassium channel signature 162 185 2.9E-34 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MKLM6_RS04940 463ed2f980dba92568a675692f4ad7f6 284 PRINTS PR00169 Potassium channel signature 220 246 2.9E-34 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MKLM6_RS04940 463ed2f980dba92568a675692f4ad7f6 284 PRINTS PR00169 Potassium channel signature 191 213 2.9E-34 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MKLM6_RS04940 463ed2f980dba92568a675692f4ad7f6 284 PRINTS PR00169 Potassium channel signature 97 117 2.9E-34 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MKLM6_RS04940 463ed2f980dba92568a675692f4ad7f6 284 PRINTS PR00169 Potassium channel signature 71 94 2.9E-34 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MKLM6_RS04940 463ed2f980dba92568a675692f4ad7f6 284 PRINTS PR00169 Potassium channel signature 29 57 2.9E-34 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MKLM6_RS04940 463ed2f980dba92568a675692f4ad7f6 284 PRINTS PR00169 Potassium channel signature 133 159 2.9E-34 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MKLM6_RS04940 463ed2f980dba92568a675692f4ad7f6 284 Pfam PF00520 Ion transport protein 37 241 7.5E-31 T 28-03-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 MKLM6_RS04940 463ed2f980dba92568a675692f4ad7f6 284 Gene3D G3DSA:1.10.287.70 162 210 1.4E-13 T 28-03-2018 MKLM6_RS04940 463ed2f980dba92568a675692f4ad7f6 284 SUPERFAMILY SSF81324 36 245 1.01E-50 T 28-03-2018 MKLM6_RS04940 463ed2f980dba92568a675692f4ad7f6 284 Gene3D G3DSA:1.20.120.350 32 161 1.9E-26 T 28-03-2018 MKLM6_RS04940 463ed2f980dba92568a675692f4ad7f6 284 Gene3D G3DSA:1.20.5.110 212 248 4.0E-12 T 28-03-2018 MKLM6_RS06880 42947fb44eb1b968ab77ed68eda97af8 398 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 13 397 1.1E-173 T 28-03-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 MKLM6_RS06880 42947fb44eb1b968ab77ed68eda97af8 398 Gene3D G3DSA:3.30.1490.20 101 197 2.7E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MKLM6_RS06880 42947fb44eb1b968ab77ed68eda97af8 398 SUPERFAMILY SSF56059 113 319 4.24E-54 T 28-03-2018 MKLM6_RS06880 42947fb44eb1b968ab77ed68eda97af8 398 SUPERFAMILY SSF51246 326 396 1.27E-18 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MKLM6_RS06880 42947fb44eb1b968ab77ed68eda97af8 398 Hamap MF_01643 Phosphoribosylglycinamide formyltransferase 2 [purT]. 7 397 51.657 T 28-03-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 MKLM6_RS06880 42947fb44eb1b968ab77ed68eda97af8 398 Gene3D G3DSA:3.30.470.20 199 396 2.2E-39 T 28-03-2018 MKLM6_RS06880 42947fb44eb1b968ab77ed68eda97af8 398 SUPERFAMILY SSF52440 3 112 1.87E-29 T 28-03-2018 IPR016185 Pre-ATP-grasp domain MKLM6_RS06880 42947fb44eb1b968ab77ed68eda97af8 398 Pfam PF02222 ATP-grasp domain 123 301 3.5E-54 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type MKLM6_RS06880 42947fb44eb1b968ab77ed68eda97af8 398 Gene3D G3DSA:3.40.50.20 15 100 5.8E-19 T 28-03-2018 MKLM6_RS09450 fbd353889c49218d312e02bb82ba86ab 321 Pfam PF02239 Cytochrome D1 heme domain 64 155 7.7E-9 T 28-03-2018 MKLM6_RS09450 fbd353889c49218d312e02bb82ba86ab 321 SUPERFAMILY SSF50974 8 319 7.59E-71 T 28-03-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 MKLM6_RS09450 fbd353889c49218d312e02bb82ba86ab 321 Gene3D G3DSA:2.130.10.10 149 257 3.8E-19 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MKLM6_RS09450 fbd353889c49218d312e02bb82ba86ab 321 Gene3D G3DSA:2.130.10.10 258 321 2.3E-9 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MKLM6_RS09450 fbd353889c49218d312e02bb82ba86ab 321 Gene3D G3DSA:2.130.10.10 22 102 6.9E-19 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MKLM6_RS09450 fbd353889c49218d312e02bb82ba86ab 321 Gene3D G3DSA:2.130.10.10 103 148 9.0E-11 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MKLM6_RS09450 fbd353889c49218d312e02bb82ba86ab 321 TIGRFAM TIGR03866 PQQ_ABC_repeats: PQQ-dependent catabolism-associated beta-propeller protein 14 321 3.2E-141 T 28-03-2018 IPR022456 PQQ-dependent catabolism-associated beta-propeller protein MKLM6_RS09450 fbd353889c49218d312e02bb82ba86ab 321 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 279 319 5.3E-14 T 28-03-2018 IPR011964 YVTN beta-propeller repeat MKLM6_RS09450 fbd353889c49218d312e02bb82ba86ab 321 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 103 144 1.2E-8 T 28-03-2018 IPR011964 YVTN beta-propeller repeat MKLM6_RS10160 30c8ee086b5003a3838d2682506acbad 99 Gene3D G3DSA:3.30.750.24 1 99 3.9E-16 T 28-03-2018 IPR002645 STAS domain MKLM6_RS10160 30c8ee086b5003a3838d2682506acbad 99 SUPERFAMILY SSF52091 1 98 4.71E-20 T 28-03-2018 IPR002645 STAS domain MKLM6_RS10160 30c8ee086b5003a3838d2682506acbad 99 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 97 2.1E-15 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 MKLM6_RS10160 30c8ee086b5003a3838d2682506acbad 99 Pfam PF01740 STAS domain 3 96 1.9E-11 T 28-03-2018 IPR002645 STAS domain MKLM6_RS22630 0213aaa4ace78e03ff3a8752a2d38c06 158 SUPERFAMILY SSF103647 45 118 3.14E-6 T 28-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 MKLM6_RS22630 0213aaa4ace78e03ff3a8752a2d38c06 158 Pfam PF05593 RHS Repeat 25 52 8.8E-5 T 28-03-2018 IPR031325 RHS repeat MKLM6_RS22630 0213aaa4ace78e03ff3a8752a2d38c06 158 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 25 51 0.0015 T 28-03-2018 IPR006530 YD repeat MKLM6_RS22630 0213aaa4ace78e03ff3a8752a2d38c06 158 Gene3D G3DSA:3.90.182.10 10 125 4.3E-13 T 28-03-2018 MKLM6_RS18625 131aad363601b80131427cdef30caadf 446 Pfam PF00072 Response regulator receiver domain 7 115 1.0E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS18625 131aad363601b80131427cdef30caadf 446 SUPERFAMILY SSF52172 1 181 3.56E-40 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS18625 131aad363601b80131427cdef30caadf 446 Pfam PF00158 Sigma-54 interaction domain 137 303 7.7E-70 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MKLM6_RS18625 131aad363601b80131427cdef30caadf 446 SMART SM00448 4 115 4.4E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS18625 131aad363601b80131427cdef30caadf 446 SUPERFAMILY SSF46689 351 445 6.27E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS18625 131aad363601b80131427cdef30caadf 446 Gene3D G3DSA:3.40.50.300 135 309 5.3E-25 T 28-03-2018 MKLM6_RS18625 131aad363601b80131427cdef30caadf 446 Gene3D G3DSA:1.10.8.60 310 381 1.3E-22 T 28-03-2018 MKLM6_RS18625 131aad363601b80131427cdef30caadf 446 Pfam PF02954 Bacterial regulatory protein, Fis family 403 443 2.7E-15 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS18625 131aad363601b80131427cdef30caadf 446 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 426 446 3.0E-10 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS18625 131aad363601b80131427cdef30caadf 446 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 409 426 3.0E-10 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS18625 131aad363601b80131427cdef30caadf 446 Gene3D G3DSA:1.10.10.60 387 446 8.3E-16 T 28-03-2018 MKLM6_RS18625 131aad363601b80131427cdef30caadf 446 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 350 359 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site MKLM6_RS18625 131aad363601b80131427cdef30caadf 446 SUPERFAMILY SSF52540 138 378 2.67E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS18625 131aad363601b80131427cdef30caadf 446 SMART SM00382 157 300 9.6E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS18625 131aad363601b80131427cdef30caadf 446 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 223 238 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MKLM6_RS18625 131aad363601b80131427cdef30caadf 446 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 161 174 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MKLM6_RS18625 131aad363601b80131427cdef30caadf 446 Gene3D G3DSA:3.40.50.2300 3 134 3.2E-30 T 28-03-2018 MKLM6_RS07845 d5694c984dad9aa1481bf4ca7ba52f51 224 SUPERFAMILY SSF52833 8 99 4.08E-18 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS07845 d5694c984dad9aa1481bf4ca7ba52f51 224 Pfam PF13417 Glutathione S-transferase, N-terminal domain 9 81 6.4E-16 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MKLM6_RS07845 d5694c984dad9aa1481bf4ca7ba52f51 224 SUPERFAMILY SSF47616 89 199 8.77E-20 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like MKLM6_RS07845 d5694c984dad9aa1481bf4ca7ba52f51 224 Gene3D G3DSA:1.20.1050.10 100 191 1.9E-16 T 28-03-2018 MKLM6_RS07845 d5694c984dad9aa1481bf4ca7ba52f51 224 Pfam PF13410 Glutathione S-transferase, C-terminal domain 126 184 9.4E-10 T 28-03-2018 MKLM6_RS07845 d5694c984dad9aa1481bf4ca7ba52f51 224 Gene3D G3DSA:3.40.30.10 8 99 1.8E-18 T 28-03-2018 MKLM6_RS14395 f8e9e4b9ce24ec6fccff882d73005d1b 155 SUPERFAMILY SSF160574 26 149 5.1E-6 T 28-03-2018 MKLM6_RS04725 96442e2a7b9903538d6f7d6b209f6e37 472 Gene3D G3DSA:3.40.120.10 4 164 3.8E-30 T 28-03-2018 MKLM6_RS04725 96442e2a7b9903538d6f7d6b209f6e37 472 SUPERFAMILY SSF53738 245 378 1.73E-7 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS04725 96442e2a7b9903538d6f7d6b209f6e37 472 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 16 139 2.9E-28 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS04725 96442e2a7b9903538d6f7d6b209f6e37 472 SUPERFAMILY SSF53738 8 145 1.96E-30 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS04725 96442e2a7b9903538d6f7d6b209f6e37 472 Gene3D G3DSA:3.30.310.50 377 471 5.2E-16 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS04725 96442e2a7b9903538d6f7d6b209f6e37 472 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 262 378 1.0E-12 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS04725 96442e2a7b9903538d6f7d6b209f6e37 472 SUPERFAMILY SSF53738 159 259 1.57E-13 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS04725 96442e2a7b9903538d6f7d6b209f6e37 472 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 406 468 2.5E-8 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS04725 96442e2a7b9903538d6f7d6b209f6e37 472 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 160 257 1.2E-8 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS04725 96442e2a7b9903538d6f7d6b209f6e37 472 Gene3D G3DSA:3.40.120.10 269 376 4.7E-21 T 28-03-2018 MKLM6_RS04725 96442e2a7b9903538d6f7d6b209f6e37 472 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 104 113 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS04725 96442e2a7b9903538d6f7d6b209f6e37 472 Gene3D G3DSA:3.40.120.10 165 268 3.7E-13 T 28-03-2018 MKLM6_RS04725 96442e2a7b9903538d6f7d6b209f6e37 472 SUPERFAMILY SSF55957 417 470 2.09E-12 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS05390 6c38373b56e4ca84f8298868a96c927d 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 240 2.6E-55 T 28-03-2018 MKLM6_RS05390 6c38373b56e4ca84f8298868a96c927d 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.5E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS05390 6c38373b56e4ca84f8298868a96c927d 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.5E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS05390 6c38373b56e4ca84f8298868a96c927d 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.5E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS05390 6c38373b56e4ca84f8298868a96c927d 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 1.5E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS05390 6c38373b56e4ca84f8298868a96c927d 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.5E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS05390 6c38373b56e4ca84f8298868a96c927d 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.5E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS05390 6c38373b56e4ca84f8298868a96c927d 241 Gene3D G3DSA:3.40.50.720 159 240 2.0E-23 T 28-03-2018 MKLM6_RS05390 6c38373b56e4ca84f8298868a96c927d 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.6E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS05390 6c38373b56e4ca84f8298868a96c927d 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.6E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS05390 6c38373b56e4ca84f8298868a96c927d 241 TIGRFAM TIGR01831 fabG_rel: putative 3-oxoacyl-(acyl-carrier-protein) reductase 5 240 1.4E-114 T 28-03-2018 IPR011285 3-oxoacyl-(acyl-carrier-protein) reductase, putative KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MKLM6_RS05390 6c38373b56e4ca84f8298868a96c927d 241 SUPERFAMILY SSF51735 2 240 2.56E-74 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS05390 6c38373b56e4ca84f8298868a96c927d 241 Gene3D G3DSA:3.40.50.720 1 158 5.9E-45 T 28-03-2018 MKLM6_RS05390 6c38373b56e4ca84f8298868a96c927d 241 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 189 2.0E-6 T 28-03-2018 MKLM6_RS02885 25750214b62fbe86a84eccf79f27fb5d 412 SUPERFAMILY SSF81891 120 361 1.06E-51 T 28-03-2018 MKLM6_RS02885 25750214b62fbe86a84eccf79f27fb5d 412 SUPERFAMILY SSF81301 1 119 1.53E-27 T 28-03-2018 MKLM6_RS02885 25750214b62fbe86a84eccf79f27fb5d 412 Pfam PF01743 Poly A polymerase head domain 3 122 1.3E-15 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MKLM6_RS02885 25750214b62fbe86a84eccf79f27fb5d 412 Gene3D G3DSA:3.30.460.10 1 118 6.1E-26 T 28-03-2018 MKLM6_RS02885 25750214b62fbe86a84eccf79f27fb5d 412 Hamap MF_01262 CCA-adding enzyme [cca]. 1 401 40.631 T 28-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 MKLM6_RS02885 25750214b62fbe86a84eccf79f27fb5d 412 Pfam PF01966 HD domain 231 318 5.9E-10 T 28-03-2018 IPR006674 HD domain MKLM6_RS02885 25750214b62fbe86a84eccf79f27fb5d 412 Hamap MF_01261 Multifunctional CCA protein [cca]. 1 407 51.871 T 28-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 MKLM6_RS02885 25750214b62fbe86a84eccf79f27fb5d 412 PIRSF PIRSF000813 1 408 1.5E-182 T 28-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 MKLM6_RS02885 25750214b62fbe86a84eccf79f27fb5d 412 Gene3D G3DSA:1.10.3090.10 119 409 3.2E-58 T 28-03-2018 MKLM6_RS02885 25750214b62fbe86a84eccf79f27fb5d 412 SMART SM00471 224 359 3.4E-5 T 28-03-2018 IPR003607 HD/PDEase domain MKLM6_RS02885 25750214b62fbe86a84eccf79f27fb5d 412 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 149 212 1.2E-10 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MKLM6_RS13090 1a1f1bc5eaac7edf172be8d3d8f7ff45 296 TIGRFAM TIGR01136 cysKM: cysteine synthase 6 294 2.9E-123 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MKLM6_RS13090 1a1f1bc5eaac7edf172be8d3d8f7ff45 296 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 7 283 1.5E-66 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MKLM6_RS13090 1a1f1bc5eaac7edf172be8d3d8f7ff45 296 Gene3D G3DSA:3.40.50.1100 136 296 2.7E-43 T 28-03-2018 MKLM6_RS13090 1a1f1bc5eaac7edf172be8d3d8f7ff45 296 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 32 50 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 MKLM6_RS13090 1a1f1bc5eaac7edf172be8d3d8f7ff45 296 TIGRFAM TIGR01138 cysM: cysteine synthase B 5 294 4.4E-146 T 28-03-2018 IPR005858 Cysteine synthase CysM GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MKLM6_RS13090 1a1f1bc5eaac7edf172be8d3d8f7ff45 296 Gene3D G3DSA:3.40.50.1100 40 135 1.7E-35 T 28-03-2018 MKLM6_RS13090 1a1f1bc5eaac7edf172be8d3d8f7ff45 296 SUPERFAMILY SSF53686 3 294 7.33E-93 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 SUPERFAMILY SSF56784 465 714 2.47E-62 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 SUPERFAMILY SSF56784 326 346 2.47E-62 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 468 486 5.7E-17 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 610 626 5.7E-17 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 642 667 5.7E-17 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 330 336 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 Pfam PF00702 haloacid dehalogenase-like hydrolase 325 624 4.2E-23 T 28-03-2018 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 Gene3D G3DSA:3.40.50.1000 507 630 8.5E-23 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 Gene3D G3DSA:3.40.1110.10 292 506 4.4E-51 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 SUPERFAMILY SSF81660 335 510 3.24E-41 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 506 517 2.0E-41 T 28-03-2018 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 528 538 2.0E-41 T 28-03-2018 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 167 181 2.0E-41 T 28-03-2018 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 328 342 2.0E-41 T 28-03-2018 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 610 629 2.0E-41 T 28-03-2018 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 634 646 2.0E-41 T 28-03-2018 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 89 359 5.8E-41 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 388 553 5.5E-20 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 584 697 6.5E-32 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 Pfam PF00122 E1-E2 ATPase 116 308 1.3E-48 T 28-03-2018 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 Gene3D G3DSA:2.70.150.10 11 229 8.8E-41 T 28-03-2018 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 Gene3D G3DSA:1.20.1110.10 631 885 3.6E-80 T 28-03-2018 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 Pfam PF00689 Cation transporting ATPase, C-terminus 694 879 3.4E-45 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 SUPERFAMILY SSF81665 660 883 1.03E-111 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 SUPERFAMILY SSF81665 229 322 1.03E-111 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 SUPERFAMILY SSF81665 2 120 1.03E-111 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 Pfam PF00690 Cation transporter/ATPase, N-terminus 4 69 9.6E-14 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 SMART SM00831 2 75 2.8E-17 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 MKLM6_RS09940 a5dcccd472006b0cda8f009d150dd2b8 905 SUPERFAMILY SSF81653 119 227 1.7E-25 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MKLM6_RS12555 bcbdd99bd0235421ed9adc97a6b8e936 272 SUPERFAMILY SSF143744 51 147 4.05E-11 T 28-03-2018 MKLM6_RS12555 bcbdd99bd0235421ed9adc97a6b8e936 272 SUPERFAMILY SSF143744 174 217 4.05E-11 T 28-03-2018 MKLM6_RS12555 bcbdd99bd0235421ed9adc97a6b8e936 272 Pfam PF03928 Haem-degrading 52 211 7.4E-9 T 28-03-2018 IPR005624 Haem-degrading MKLM6_RS12800 211a7786b31987442b2b375042be90b8 913 Gene3D G3DSA:3.20.20.60 534 910 1.5E-109 T 28-03-2018 MKLM6_RS12800 211a7786b31987442b2b375042be90b8 913 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 449 460 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 MKLM6_RS12800 211a7786b31987442b2b375042be90b8 913 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 4 907 0.0 T 28-03-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MKLM6_RS12800 211a7786b31987442b2b375042be90b8 913 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 18 291 2.7E-40 T 28-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 MKLM6_RS12800 211a7786b31987442b2b375042be90b8 913 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 301 357 3.8E-8 T 28-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 MKLM6_RS12800 211a7786b31987442b2b375042be90b8 913 Gene3D G3DSA:1.10.189.10 344 391 3.5E-16 T 28-03-2018 MKLM6_RS12800 211a7786b31987442b2b375042be90b8 913 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 519 906 2.9E-87 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 MKLM6_RS12800 211a7786b31987442b2b375042be90b8 913 Gene3D G3DSA:3.30.470.20 245 342 1.9E-22 T 28-03-2018 MKLM6_RS12800 211a7786b31987442b2b375042be90b8 913 SUPERFAMILY SSF51621 510 645 3.66E-110 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MKLM6_RS12800 211a7786b31987442b2b375042be90b8 913 SUPERFAMILY SSF51621 683 906 3.66E-110 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MKLM6_RS12800 211a7786b31987442b2b375042be90b8 913 Gene3D G3DSA:1.20.80.30 116 197 2.3E-28 T 28-03-2018 MKLM6_RS12800 211a7786b31987442b2b375042be90b8 913 Pfam PF00391 PEP-utilising enzyme, mobile domain 421 502 2.4E-24 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MKLM6_RS12800 211a7786b31987442b2b375042be90b8 913 PIRSF PIRSF000853 2 912 0.0 T 28-03-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MKLM6_RS12800 211a7786b31987442b2b375042be90b8 913 SUPERFAMILY SSF52009 385 511 6.67E-35 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MKLM6_RS12800 211a7786b31987442b2b375042be90b8 913 Gene3D G3DSA:3.30.1490.20 3 115 5.0E-30 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MKLM6_RS12800 211a7786b31987442b2b375042be90b8 913 SUPERFAMILY SSF56059 3 379 4.36E-124 T 28-03-2018 MKLM6_RS12800 211a7786b31987442b2b375042be90b8 913 Gene3D G3DSA:3.50.30.10 392 533 5.1E-38 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MKLM6_RS21665 62bf52a4e54b1693823158d4e88d759c 605 Pfam PF00009 Elongation factor Tu GTP binding domain 4 194 2.3E-55 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS21665 62bf52a4e54b1693823158d4e88d759c 605 Gene3D G3DSA:3.30.70.240 401 481 2.6E-19 T 28-03-2018 MKLM6_RS21665 62bf52a4e54b1693823158d4e88d759c 605 SUPERFAMILY SSF50447 180 300 1.06E-28 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain MKLM6_RS21665 62bf52a4e54b1693823158d4e88d759c 605 Gene3D G3DSA:3.40.50.300 2 67 9.0E-11 T 28-03-2018 MKLM6_RS21665 62bf52a4e54b1693823158d4e88d759c 605 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 134 2.3E-22 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MKLM6_RS21665 62bf52a4e54b1693823158d4e88d759c 605 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site MKLM6_RS21665 62bf52a4e54b1693823158d4e88d759c 605 Gene3D G3DSA:3.40.50.300 68 191 6.7E-30 T 28-03-2018 MKLM6_RS21665 62bf52a4e54b1693823158d4e88d759c 605 SUPERFAMILY SSF54980 302 387 7.91E-16 T 28-03-2018 IPR035647 EF-G domain III/V-like MKLM6_RS21665 62bf52a4e54b1693823158d4e88d759c 605 PRINTS PR00315 GTP-binding elongation factor signature 123 132 1.4E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS21665 62bf52a4e54b1693823158d4e88d759c 605 PRINTS PR00315 GTP-binding elongation factor signature 87 98 1.4E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS21665 62bf52a4e54b1693823158d4e88d759c 605 PRINTS PR00315 GTP-binding elongation factor signature 51 59 1.4E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS21665 62bf52a4e54b1693823158d4e88d759c 605 PRINTS PR00315 GTP-binding elongation factor signature 71 81 1.4E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS21665 62bf52a4e54b1693823158d4e88d759c 605 PRINTS PR00315 GTP-binding elongation factor signature 7 20 1.4E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS21665 62bf52a4e54b1693823158d4e88d759c 605 Gene3D G3DSA:2.40.50.250 483 573 6.7E-40 T 28-03-2018 MKLM6_RS21665 62bf52a4e54b1693823158d4e88d759c 605 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 5 599 3.6E-292 T 28-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 MKLM6_RS21665 62bf52a4e54b1693823158d4e88d759c 605 SUPERFAMILY SSF52540 3 219 2.77E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS21665 62bf52a4e54b1693823158d4e88d759c 605 Pfam PF00679 Elongation factor G C-terminus 396 477 3.8E-21 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like MKLM6_RS21665 62bf52a4e54b1693823158d4e88d759c 605 Pfam PF03144 Elongation factor Tu domain 2 219 289 9.3E-9 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MKLM6_RS21665 62bf52a4e54b1693823158d4e88d759c 605 SUPERFAMILY SSF54980 398 513 1.06E-28 T 28-03-2018 IPR035647 EF-G domain III/V-like MKLM6_RS21665 62bf52a4e54b1693823158d4e88d759c 605 Gene3D G3DSA:3.30.70.870 303 400 6.2E-34 T 28-03-2018 MKLM6_RS21665 62bf52a4e54b1693823158d4e88d759c 605 Gene3D G3DSA:2.40.30.10 192 302 6.6E-22 T 28-03-2018 MKLM6_RS10755 6e7fafa0bb98dada3e627e9d8a7442a2 215 SUPERFAMILY SSF52172 4 132 4.84E-32 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS10755 6e7fafa0bb98dada3e627e9d8a7442a2 215 Gene3D G3DSA:3.40.50.2300 4 128 5.7E-33 T 28-03-2018 MKLM6_RS10755 6e7fafa0bb98dada3e627e9d8a7442a2 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 2.1E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS10755 6e7fafa0bb98dada3e627e9d8a7442a2 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 2.1E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS10755 6e7fafa0bb98dada3e627e9d8a7442a2 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 2.1E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS10755 6e7fafa0bb98dada3e627e9d8a7442a2 215 Gene3D G3DSA:1.10.10.10 129 215 9.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS10755 6e7fafa0bb98dada3e627e9d8a7442a2 215 Pfam PF00072 Response regulator receiver domain 7 118 1.5E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS10755 6e7fafa0bb98dada3e627e9d8a7442a2 215 SUPERFAMILY SSF46894 141 212 8.16E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MKLM6_RS10755 6e7fafa0bb98dada3e627e9d8a7442a2 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 207 7.8E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS10755 6e7fafa0bb98dada3e627e9d8a7442a2 215 SMART SM00448 5 118 4.3E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS10755 6e7fafa0bb98dada3e627e9d8a7442a2 215 SMART SM00421 150 207 1.5E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS02060 a1a68d412ae99e7289e73755f90e6a95 669 SUPERFAMILY SSF52540 4 641 2.66E-161 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS02060 a1a68d412ae99e7289e73755f90e6a95 669 Gene3D G3DSA:3.40.50.300 4 273 2.2E-56 T 28-03-2018 MKLM6_RS02060 a1a68d412ae99e7289e73755f90e6a95 669 Pfam PF00580 UvrD/REP helicase N-terminal domain 5 267 9.8E-70 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MKLM6_RS02060 a1a68d412ae99e7289e73755f90e6a95 669 Pfam PF13361 UvrD-like helicase C-terminal domain 273 615 3.6E-71 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MKLM6_RS02060 a1a68d412ae99e7289e73755f90e6a95 669 Gene3D G3DSA:3.40.50.300 276 381 2.8E-22 T 28-03-2018 MKLM6_RS02060 a1a68d412ae99e7289e73755f90e6a95 669 Gene3D G3DSA:3.40.50.300 389 665 2.1E-41 T 28-03-2018 MKLM6_RS02060 a1a68d412ae99e7289e73755f90e6a95 669 TIGRFAM TIGR01074 rep: ATP-dependent DNA helicase Rep 4 668 1.0E-295 T 28-03-2018 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 MKLM6_RS02060 a1a68d412ae99e7289e73755f90e6a95 669 Hamap MF_01920 ATP-dependent DNA helicase Rep [rep]. 3 669 39.056 T 28-03-2018 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 MKLM6_RS16415 61a8b5de3efd9dec6f08cff999edd316 250 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MKLM6_RS16415 61a8b5de3efd9dec6f08cff999edd316 250 Pfam PF06426 Serine acetyltransferase, N-terminal 4 35 1.0E-4 T 28-03-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 MKLM6_RS16415 61a8b5de3efd9dec6f08cff999edd316 250 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 150 8.4E-7 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS16415 61a8b5de3efd9dec6f08cff999edd316 250 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 72 108 2.0E-4 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS16415 61a8b5de3efd9dec6f08cff999edd316 250 SUPERFAMILY SSF51161 3 169 1.52E-55 T 28-03-2018 IPR011004 Trimeric LpxA-like MKLM6_RS16415 61a8b5de3efd9dec6f08cff999edd316 250 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 6 165 1.1E-76 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 MKLM6_RS16415 61a8b5de3efd9dec6f08cff999edd316 250 Gene3D G3DSA:2.160.10.10 64 233 2.3E-39 T 28-03-2018 MKLM6_RS16415 61a8b5de3efd9dec6f08cff999edd316 250 Gene3D G3DSA:1.10.3130.10 1 63 9.8E-26 T 28-03-2018 MKLM6_RS04040 f166fa07235ae03d45373ded9f4ca5eb 725 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 10 692 1.8E-210 T 28-03-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 MKLM6_RS04040 f166fa07235ae03d45373ded9f4ca5eb 725 Gene3D G3DSA:3.20.20.80 149 582 1.0E-111 T 28-03-2018 MKLM6_RS04040 f166fa07235ae03d45373ded9f4ca5eb 725 Gene3D G3DSA:2.60.40.1180 583 696 2.0E-22 T 28-03-2018 MKLM6_RS04040 f166fa07235ae03d45373ded9f4ca5eb 725 Pfam PF00128 Alpha amylase, catalytic domain 177 278 4.1E-13 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MKLM6_RS04040 f166fa07235ae03d45373ded9f4ca5eb 725 Gene3D G3DSA:2.60.40.10 1 148 8.6E-29 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS04040 f166fa07235ae03d45373ded9f4ca5eb 725 SMART SM00642 159 570 3.9E-10 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MKLM6_RS04040 f166fa07235ae03d45373ded9f4ca5eb 725 SUPERFAMILY SSF51011 591 692 1.15E-16 T 28-03-2018 MKLM6_RS04040 f166fa07235ae03d45373ded9f4ca5eb 725 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 16 107 3.3E-12 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 MKLM6_RS04040 f166fa07235ae03d45373ded9f4ca5eb 725 SUPERFAMILY SSF81296 10 147 6.72E-33 T 28-03-2018 IPR014756 Immunoglobulin E-set MKLM6_RS04040 f166fa07235ae03d45373ded9f4ca5eb 725 SUPERFAMILY SSF51445 134 473 7.3E-130 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily MKLM6_RS04040 f166fa07235ae03d45373ded9f4ca5eb 725 SUPERFAMILY SSF51445 502 576 7.3E-130 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 Gene3D G3DSA:3.30.450.20 65 182 6.2E-9 T 28-03-2018 MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 SMART SM00052 752 999 4.9E-108 T 28-03-2018 IPR001633 EAL domain MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 Pfam PF13426 PAS domain 467 569 1.7E-14 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 Pfam PF13426 PAS domain 345 447 2.5E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 Pfam PF02743 Cache domain 53 222 3.2E-13 T 28-03-2018 IPR033479 Double Cache domain 1 MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 335 454 3.4E-24 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 454 573 2.1E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 Gene3D G3DSA:3.30.450.20 322 454 5.7E-22 T 28-03-2018 MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 Gene3D G3DSA:3.30.70.270 596 750 9.6E-62 T 28-03-2018 MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 SMART SM00086 528 570 0.021 T 28-03-2018 IPR001610 PAC motif MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 SMART SM00086 407 448 0.015 T 28-03-2018 IPR001610 PAC motif MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 SUPERFAMILY SSF141868 758 1006 8.5E-88 T 28-03-2018 IPR001633 EAL domain MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 SMART SM00091 456 522 1.8E-6 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 SMART SM00091 335 401 1.2E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 SMART SM00267 570 742 2.5E-63 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 Gene3D G3DSA:3.30.450.20 183 301 1.3E-5 T 28-03-2018 MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 SUPERFAMILY SSF55785 463 568 3.14E-26 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 Gene3D G3DSA:3.40.50.10600 455 595 3.2E-25 T 28-03-2018 MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 Pfam PF00563 EAL domain 758 994 4.9E-72 T 28-03-2018 IPR001633 EAL domain MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 579 741 1.0E-45 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 SUPERFAMILY SSF55073 586 743 1.57E-50 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 SUPERFAMILY SSF55785 329 446 7.15E-23 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 Gene3D G3DSA:3.20.20.450 751 1009 3.1E-97 T 28-03-2018 IPR001633 EAL domain MKLM6_RS10850 c2646463ae1130561b446f8a56fcbe9e 1012 Pfam PF00990 Diguanylate cyclase, GGDEF domain 581 737 1.5E-51 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS18100 0897bcf446cc12a846a5b2d56318b55a 2515 SUPERFAMILY SSF51120 2318 2442 4.84E-10 T 28-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MKLM6_RS18100 0897bcf446cc12a846a5b2d56318b55a 2515 SUPERFAMILY SSF51120 2169 2304 4.97E-9 T 28-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MKLM6_RS18100 0897bcf446cc12a846a5b2d56318b55a 2515 Gene3D G3DSA:2.150.10.10 2266 2466 3.7E-9 T 28-03-2018 MKLM6_RS18100 0897bcf446cc12a846a5b2d56318b55a 2515 Gene3D G3DSA:3.80.10.10 1881 2155 4.9E-4 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like MKLM6_RS18100 0897bcf446cc12a846a5b2d56318b55a 2515 Gene3D G3DSA:3.80.10.10 1240 1679 6.2E-7 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like MKLM6_RS18100 0897bcf446cc12a846a5b2d56318b55a 2515 Gene3D G3DSA:3.80.10.10 708 1065 0.0061 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like MKLM6_RS18100 0897bcf446cc12a846a5b2d56318b55a 2515 Gene3D G3DSA:3.80.10.10 48 597 0.0042 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like MKLM6_RS18100 0897bcf446cc12a846a5b2d56318b55a 2515 Gene3D G3DSA:3.80.10.10 1680 1869 0.018 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like MKLM6_RS18100 0897bcf446cc12a846a5b2d56318b55a 2515 PRINTS PR00313 NodO calcium binding signature 2352 2360 2.1E-6 T 28-03-2018 MKLM6_RS18100 0897bcf446cc12a846a5b2d56318b55a 2515 PRINTS PR00313 NodO calcium binding signature 2214 2222 2.1E-6 T 28-03-2018 MKLM6_RS18100 0897bcf446cc12a846a5b2d56318b55a 2515 PRINTS PR00313 NodO calcium binding signature 2361 2370 2.1E-6 T 28-03-2018 MKLM6_RS18100 0897bcf446cc12a846a5b2d56318b55a 2515 PRINTS PR00313 NodO calcium binding signature 2202 2213 2.1E-6 T 28-03-2018 MKLM6_RS13955 ecd4ac45b8667afa40a40169088113ed 369 SMART SM00448 11 124 7.1E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS13955 ecd4ac45b8667afa40a40169088113ed 369 SMART SM00471 173 325 7.5E-8 T 28-03-2018 IPR003607 HD/PDEase domain MKLM6_RS13955 ecd4ac45b8667afa40a40169088113ed 369 SUPERFAMILY SSF109604 154 356 4.71E-33 T 28-03-2018 MKLM6_RS13955 ecd4ac45b8667afa40a40169088113ed 369 SUPERFAMILY SSF52172 6 145 2.56E-37 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS13955 ecd4ac45b8667afa40a40169088113ed 369 Pfam PF13487 HD domain 235 307 4.0E-17 T 28-03-2018 MKLM6_RS13955 ecd4ac45b8667afa40a40169088113ed 369 Pfam PF00072 Response regulator receiver domain 13 124 5.9E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS13955 ecd4ac45b8667afa40a40169088113ed 369 Gene3D G3DSA:3.40.50.2300 3 137 2.1E-33 T 28-03-2018 MKLM6_RS13955 ecd4ac45b8667afa40a40169088113ed 369 Gene3D G3DSA:1.10.3210.10 138 366 3.2E-47 T 28-03-2018 MKLM6_RS16315 bc9a5357241fdedf8875032e4c30aef8 67 Pfam PF12728 Helix-turn-helix domain 17 63 1.2E-7 T 28-03-2018 MKLM6_RS16315 bc9a5357241fdedf8875032e4c30aef8 67 SUPERFAMILY SSF46955 19 63 6.77E-5 T 28-03-2018 IPR009061 Putative DNA-binding domain MKLM6_RS16315 bc9a5357241fdedf8875032e4c30aef8 67 Gene3D G3DSA:1.10.10.10 12 67 3.9E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS06205 1ee8f45ce81a36e8ff68a8ca299d0293 150 Pfam PF13274 Protein of unknown function (DUF4065) 28 122 4.1E-16 T 28-03-2018 IPR025272 Domain of unknown function DUF4065 MKLM6_RS16280 c1d591cced2e9b6d49062ce77d347b14 408 ProSitePatterns PS01007 Transposases, Mutator family, signature. 239 263 - T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS16280 c1d591cced2e9b6d49062ce77d347b14 408 Pfam PF00872 Transposase, Mutator family 20 384 6.7E-119 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 798 1018 1.4E-48 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 SMART SM00878 336 440 8.5E-53 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 Gene3D G3DSA:3.30.470.20 209 442 4.8E-92 T 28-03-2018 MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 SUPERFAMILY SSF52440 1 112 2.73E-48 T 28-03-2018 IPR016185 Pre-ATP-grasp domain MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 SUPERFAMILY SSF50891 625 750 8.34E-33 T 28-03-2018 IPR029000 Cyclophilin-like domain MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 Pfam PF00364 Biotin-requiring enzyme 1135 1195 3.5E-17 T 28-03-2018 IPR000089 Biotin/lipoyl attachment MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 SUPERFAMILY SSF51230 1123 1196 1.7E-20 T 28-03-2018 IPR011053 Single hybrid motif MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 Pfam PF02785 Biotin carboxylase C-terminal domain 336 439 9.9E-35 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 SMART SM00796 797 1029 1.4E-117 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 SUPERFAMILY SSF160467 798 889 1.11E-18 T 28-03-2018 MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 472 743 2.3E-88 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 TIGRFAM TIGR02712 urea_carbox: urea carboxylase 2 1197 0.0 T 28-03-2018 IPR014084 Urea carboxylase KEGG: 00220+3.5.1.54+6.3.4.6|KEGG: 00791+3.5.1.54+6.3.4.6|MetaCyc: PWY-5169|MetaCyc: PWY-5703 MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 Gene3D G3DSA:3.30.1360.40 781 878 1.1E-29 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 Gene3D G3DSA:2.40.50.100 1117 1202 2.2E-18 T 28-03-2018 MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 Gene3D G3DSA:3.30.1490.20 124 208 1.0E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 Gene3D G3DSA:2.40.100.10 884 1047 3.6E-49 T 28-03-2018 IPR029000 Cyclophilin-like domain MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 448 763 1.1E-90 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 SUPERFAMILY SSF51246 330 441 2.09E-35 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 SUPERFAMILY SSF50891 913 1045 1.29E-26 T 28-03-2018 IPR029000 Cyclophilin-like domain MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 109 1.8E-45 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 319 2.2E-67 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 Gene3D G3DSA:3.40.50.20 1 123 3.4E-52 T 28-03-2018 MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 SUPERFAMILY SSF56059 83 350 2.65E-67 T 28-03-2018 MKLM6_RS17685 aa71de287ae3f71d7522bd346ec84c33 1202 SMART SM00797 471 761 1.9E-168 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B MKLM6_RS21185 a9c32378ffcc55b29d5168ffb4313d1a 553 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 5 552 6.5E-217 T 28-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MKLM6_RS21185 a9c32378ffcc55b29d5168ffb4313d1a 553 Gene3D G3DSA:3.20.20.70 8 374 2.3E-106 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS21185 a9c32378ffcc55b29d5168ffb4313d1a 553 SUPERFAMILY SSF110921 445 551 1.29E-26 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MKLM6_RS21185 a9c32378ffcc55b29d5168ffb4313d1a 553 Pfam PF08502 LeuA allosteric (dimerisation) domain 421 551 1.2E-20 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MKLM6_RS21185 a9c32378ffcc55b29d5168ffb4313d1a 553 SMART SM00917 420 552 6.1E-25 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MKLM6_RS21185 a9c32378ffcc55b29d5168ffb4313d1a 553 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 241 254 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MKLM6_RS21185 a9c32378ffcc55b29d5168ffb4313d1a 553 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 6 553 50.439 T 28-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MKLM6_RS21185 a9c32378ffcc55b29d5168ffb4313d1a 553 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 38 54 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MKLM6_RS21185 a9c32378ffcc55b29d5168ffb4313d1a 553 Pfam PF00682 HMGL-like 31 309 7.8E-73 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MKLM6_RS21185 a9c32378ffcc55b29d5168ffb4313d1a 553 SUPERFAMILY SSF51569 20 328 7.87E-96 T 28-03-2018 MKLM6_RS21185 a9c32378ffcc55b29d5168ffb4313d1a 553 SUPERFAMILY SSF89000 386 436 5.49E-14 T 28-03-2018 MKLM6_RS14940 28e2dda518ebdd7cd6188b395b94c6c4 430 TIGRFAM TIGR00836 amt: ammonium transporter 30 427 1.4E-135 T 28-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 MKLM6_RS14940 28e2dda518ebdd7cd6188b395b94c6c4 430 ProSitePatterns PS01219 Ammonium transporters signature. 184 209 - T 28-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 MKLM6_RS14940 28e2dda518ebdd7cd6188b395b94c6c4 430 Pfam PF00909 Ammonium Transporter Family 32 427 6.9E-117 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 MKLM6_RS14940 28e2dda518ebdd7cd6188b395b94c6c4 430 Gene3D G3DSA:1.10.3430.10 22 408 1.8E-131 T 28-03-2018 MKLM6_RS14940 28e2dda518ebdd7cd6188b395b94c6c4 430 SUPERFAMILY SSF111352 26 408 9.42E-128 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 MKLM6_RS18170 d8444a5bbafc51a3411050793f39a6f0 468 Pfam PF00171 Aldehyde dehydrogenase family 2 451 1.9E-132 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MKLM6_RS18170 d8444a5bbafc51a3411050793f39a6f0 468 SUPERFAMILY SSF53720 2 453 7.72E-133 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MKLM6_RS18170 d8444a5bbafc51a3411050793f39a6f0 468 Gene3D G3DSA:3.40.605.10 1 245 6.1E-69 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MKLM6_RS18170 d8444a5bbafc51a3411050793f39a6f0 468 Gene3D G3DSA:3.40.309.10 246 438 4.2E-63 T 28-03-2018 MKLM6_RS02470 5ed822adbeec95c3eaaf15f260aa7497 156 SUPERFAMILY SSF50475 8 146 1.01E-18 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MKLM6_RS02470 5ed822adbeec95c3eaaf15f260aa7497 156 Gene3D G3DSA:2.30.110.10 1 154 9.1E-18 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MKLM6_RS02470 5ed822adbeec95c3eaaf15f260aa7497 156 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 93 5.2E-6 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MKLM6_RS02470 5ed822adbeec95c3eaaf15f260aa7497 156 PIRSF PIRSF004633 3 151 4.4E-28 T 28-03-2018 IPR014419 Heme utilization protein with pyridoxamine 5'-phosphate domain MKLM6_RS15560 32611961a84991f3c18bbe0ac4207cdf 711 Pfam PF00270 DEAD/DEAH box helicase 23 181 2.6E-20 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MKLM6_RS15560 32611961a84991f3c18bbe0ac4207cdf 711 Gene3D G3DSA:1.10.150.80 516 603 2.5E-27 T 28-03-2018 MKLM6_RS15560 32611961a84991f3c18bbe0ac4207cdf 711 SMART SM00487 15 211 6.7E-30 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MKLM6_RS15560 32611961a84991f3c18bbe0ac4207cdf 711 SUPERFAMILY SSF47819 526 599 3.71E-23 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 MKLM6_RS15560 32611961a84991f3c18bbe0ac4207cdf 711 SUPERFAMILY SSF52540 201 454 2.55E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS15560 32611961a84991f3c18bbe0ac4207cdf 711 Gene3D G3DSA:3.40.50.300 203 398 5.6E-45 T 28-03-2018 MKLM6_RS15560 32611961a84991f3c18bbe0ac4207cdf 711 SUPERFAMILY SSF52540 4 189 2.54E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS15560 32611961a84991f3c18bbe0ac4207cdf 711 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 8 597 5.3E-250 T 28-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 MKLM6_RS15560 32611961a84991f3c18bbe0ac4207cdf 711 SMART SM00956 406 509 1.0E-53 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 MKLM6_RS15560 32611961a84991f3c18bbe0ac4207cdf 711 Pfam PF00570 HRDC domain 531 596 1.6E-22 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MKLM6_RS15560 32611961a84991f3c18bbe0ac4207cdf 711 Gene3D G3DSA:1.10.10.60 604 646 2.0E-5 T 28-03-2018 MKLM6_RS15560 32611961a84991f3c18bbe0ac4207cdf 711 Pfam PF16124 RecQ zinc-binding 337 399 6.4E-19 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain MKLM6_RS15560 32611961a84991f3c18bbe0ac4207cdf 711 Pfam PF09382 RQC domain 402 512 1.5E-39 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 MKLM6_RS15560 32611961a84991f3c18bbe0ac4207cdf 711 SMART SM00490 244 325 2.2E-26 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS15560 32611961a84991f3c18bbe0ac4207cdf 711 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 9 457 5.6E-164 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 MKLM6_RS15560 32611961a84991f3c18bbe0ac4207cdf 711 SMART SM00341 526 606 1.3E-14 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MKLM6_RS15560 32611961a84991f3c18bbe0ac4207cdf 711 Gene3D G3DSA:1.10.10.10 399 515 1.4E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS15560 32611961a84991f3c18bbe0ac4207cdf 711 Pfam PF14493 Helix-turn-helix domain 611 703 4.1E-17 T 28-03-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 MKLM6_RS15560 32611961a84991f3c18bbe0ac4207cdf 711 Pfam PF00271 Helicase conserved C-terminal domain 218 324 1.4E-17 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS15560 32611961a84991f3c18bbe0ac4207cdf 711 Gene3D G3DSA:3.40.50.300 2 201 1.4E-32 T 28-03-2018 MKLM6_RS08780 1be93387b4e3fe112f3c4355badc568f 727 SUPERFAMILY SSF55021 654 725 2.91E-8 T 28-03-2018 MKLM6_RS08780 1be93387b4e3fe112f3c4355badc568f 727 Gene3D G3DSA:3.30.460.10 211 344 3.8E-42 T 28-03-2018 MKLM6_RS08780 1be93387b4e3fe112f3c4355badc568f 727 SUPERFAMILY SSF81271 394 466 4.09E-20 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MKLM6_RS08780 1be93387b4e3fe112f3c4355badc568f 727 SMART SM00954 254 364 1.4E-61 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 MKLM6_RS08780 1be93387b4e3fe112f3c4355badc568f 727 SUPERFAMILY SSF81301 211 384 7.19E-62 T 28-03-2018 MKLM6_RS08780 1be93387b4e3fe112f3c4355badc568f 727 SUPERFAMILY SSF109604 23 209 4.39E-69 T 28-03-2018 MKLM6_RS08780 1be93387b4e3fe112f3c4355badc568f 727 SMART SM00471 60 172 6.8E-4 T 28-03-2018 IPR003607 HD/PDEase domain MKLM6_RS08780 1be93387b4e3fe112f3c4355badc568f 727 Pfam PF04607 Region found in RelA / SpoT proteins 254 364 1.6E-35 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 MKLM6_RS08780 1be93387b4e3fe112f3c4355badc568f 727 Pfam PF13291 ACT domain 648 724 1.2E-14 T 28-03-2018 IPR002912 ACT domain MKLM6_RS08780 1be93387b4e3fe112f3c4355badc568f 727 Pfam PF02824 TGS domain 407 466 1.9E-19 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 MKLM6_RS08780 1be93387b4e3fe112f3c4355badc568f 727 Gene3D G3DSA:3.30.70.260 647 727 8.3E-10 T 28-03-2018 MKLM6_RS08780 1be93387b4e3fe112f3c4355badc568f 727 Gene3D G3DSA:3.10.20.30 401 474 3.6E-22 T 28-03-2018 IPR012675 Beta-grasp domain MKLM6_RS08780 1be93387b4e3fe112f3c4355badc568f 727 Pfam PF13328 HD domain 45 194 9.3E-48 T 28-03-2018 IPR003607 HD/PDEase domain MKLM6_RS08780 1be93387b4e3fe112f3c4355badc568f 727 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 45 724 7.3E-241 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 MKLM6_RS17860 96230100ec79fe6730a47dc8218b458b 143 Pfam PF06841 T4-like virus tail tube protein gp19 8 141 5.7E-38 T 28-03-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 MKLM6_RS17860 96230100ec79fe6730a47dc8218b458b 143 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 5 141 4.0E-37 T 28-03-2018 IPR011747 Conserved hypothetical protein CHP02241 MKLM6_RS12265 d4e062c4b38412c06d9501bc5e74489b 269 Pfam PF00975 Thioesterase domain 20 241 6.8E-48 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 MKLM6_RS12265 d4e062c4b38412c06d9501bc5e74489b 269 SMART SM00824 Thioesterase 21 199 0.0029 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 MKLM6_RS12265 d4e062c4b38412c06d9501bc5e74489b 269 SUPERFAMILY SSF53474 6 242 7.08E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS12265 d4e062c4b38412c06d9501bc5e74489b 269 Gene3D G3DSA:3.40.50.1820 2 246 5.1E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS18485 e29d7b93a16f32e714f24313779a2974 164 SUPERFAMILY SSF160369 4 158 1.7E-46 T 28-03-2018 MKLM6_RS18485 e29d7b93a16f32e714f24313779a2974 164 Pfam PF00466 Ribosomal protein L10 6 101 3.9E-24 T 28-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 MKLM6_RS18485 e29d7b93a16f32e714f24313779a2974 164 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 28-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18485 e29d7b93a16f32e714f24313779a2974 164 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 161 26.221 T 28-03-2018 IPR022973 Ribosomal protein L10 MKLM6_RS14980 315b3891140168157370720b986f2764 473 Pfam PF00158 Sigma-54 interaction domain 143 310 3.3E-71 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MKLM6_RS14980 315b3891140168157370720b986f2764 473 Gene3D G3DSA:3.40.50.2300 3 140 5.0E-36 T 28-03-2018 MKLM6_RS14980 315b3891140168157370720b986f2764 473 SUPERFAMILY SSF52172 6 188 1.17E-43 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS14980 315b3891140168157370720b986f2764 473 Gene3D G3DSA:1.10.10.60 388 472 2.3E-23 T 28-03-2018 MKLM6_RS14980 315b3891140168157370720b986f2764 473 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 452 472 2.0E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS14980 315b3891140168157370720b986f2764 473 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 435 452 2.0E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS14980 315b3891140168157370720b986f2764 473 Pfam PF00072 Response regulator receiver domain 7 116 5.8E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14980 315b3891140168157370720b986f2764 473 Gene3D G3DSA:1.10.8.60 316 387 3.5E-20 T 28-03-2018 MKLM6_RS14980 315b3891140168157370720b986f2764 473 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 229 244 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MKLM6_RS14980 315b3891140168157370720b986f2764 473 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 167 180 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MKLM6_RS14980 315b3891140168157370720b986f2764 473 SMART SM00382 163 306 2.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS14980 315b3891140168157370720b986f2764 473 SMART SM00448 5 116 6.9E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14980 315b3891140168157370720b986f2764 473 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 7 469 2.5E-222 T 28-03-2018 IPR010114 Signal transduction response regulator, nitrogen regulation NR(I) GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 MKLM6_RS14980 315b3891140168157370720b986f2764 473 Pfam PF02954 Bacterial regulatory protein, Fis family 430 469 2.7E-11 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS14980 315b3891140168157370720b986f2764 473 Gene3D G3DSA:3.40.50.300 141 315 9.6E-31 T 28-03-2018 MKLM6_RS14980 315b3891140168157370720b986f2764 473 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 356 365 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site MKLM6_RS14980 315b3891140168157370720b986f2764 473 SUPERFAMILY SSF52540 142 386 6.49E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS14980 315b3891140168157370720b986f2764 473 SUPERFAMILY SSF46689 383 471 6.72E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS02775 7a677bb62b5b121d5a565b281bc0d2ab 744 SUPERFAMILY SSF50341 605 739 5.1E-30 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS02775 7a677bb62b5b121d5a565b281bc0d2ab 744 SMART SM01231 357 418 2.1E-15 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 MKLM6_RS02775 7a677bb62b5b121d5a565b281bc0d2ab 744 SMART SM00387 463 606 2.9E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS02775 7a677bb62b5b121d5a565b281bc0d2ab 744 SUPERFAMILY SSF47384 358 419 1.33E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS02775 7a677bb62b5b121d5a565b281bc0d2ab 744 Gene3D G3DSA:1.20.120.160 3 146 3.2E-34 T 28-03-2018 MKLM6_RS02775 7a677bb62b5b121d5a565b281bc0d2ab 744 Gene3D G3DSA:2.40.50.180 642 684 4.7E-9 T 28-03-2018 MKLM6_RS02775 7a677bb62b5b121d5a565b281bc0d2ab 744 SMART SM00260 598 739 2.8E-37 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS02775 7a677bb62b5b121d5a565b281bc0d2ab 744 SMART SM00073 6 103 6.2E-25 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS02775 7a677bb62b5b121d5a565b281bc0d2ab 744 Gene3D G3DSA:1.10.287.560 357 419 4.4E-15 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 MKLM6_RS02775 7a677bb62b5b121d5a565b281bc0d2ab 744 Pfam PF01627 Hpt domain 8 97 1.1E-17 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS02775 7a677bb62b5b121d5a565b281bc0d2ab 744 Gene3D G3DSA:3.30.565.10 421 605 1.6E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS02775 7a677bb62b5b121d5a565b281bc0d2ab 744 Pfam PF01584 CheW-like domain 612 740 8.0E-24 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS02775 7a677bb62b5b121d5a565b281bc0d2ab 744 SUPERFAMILY SSF55874 421 604 6.02E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS02775 7a677bb62b5b121d5a565b281bc0d2ab 744 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 466 605 2.9E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS02775 7a677bb62b5b121d5a565b281bc0d2ab 744 Gene3D G3DSA:2.30.30.40 606 641 0.015 T 28-03-2018 MKLM6_RS02775 7a677bb62b5b121d5a565b281bc0d2ab 744 Gene3D G3DSA:2.30.30.40 685 739 4.8E-21 T 28-03-2018 MKLM6_RS02775 7a677bb62b5b121d5a565b281bc0d2ab 744 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 358 418 2.4E-11 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 MKLM6_RS02775 7a677bb62b5b121d5a565b281bc0d2ab 744 PRINTS PR00344 Bacterial sensor protein C-terminal signature 566 584 8.4E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS02775 7a677bb62b5b121d5a565b281bc0d2ab 744 PRINTS PR00344 Bacterial sensor protein C-terminal signature 550 560 8.4E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS02775 7a677bb62b5b121d5a565b281bc0d2ab 744 PRINTS PR00344 Bacterial sensor protein C-terminal signature 508 522 8.4E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS02775 7a677bb62b5b121d5a565b281bc0d2ab 744 PRINTS PR00344 Bacterial sensor protein C-terminal signature 590 603 8.4E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS02775 7a677bb62b5b121d5a565b281bc0d2ab 744 SUPERFAMILY SSF47226 6 127 7.85E-32 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 Pfam PF13432 Tetratricopeptide repeat 480 541 0.0017 T 28-03-2018 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 Pfam PF13432 Tetratricopeptide repeat 549 608 1.4E-5 T 28-03-2018 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 Pfam PF13432 Tetratricopeptide repeat 354 404 6.0E-5 T 28-03-2018 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 Gene3D G3DSA:1.25.40.10 354 437 1.8E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 SUPERFAMILY SSF48452 31 198 4.17E-29 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 SUPERFAMILY SSF48452 301 442 9.86E-25 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 SUPERFAMILY SSF48452 490 542 9.86E-25 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 Gene3D G3DSA:1.25.40.10 189 263 2.5E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 SUPERFAMILY SSF48452 452 639 5.54E-25 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 Gene3D G3DSA:1.10.10.10 681 729 0.1 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 Gene3D G3DSA:1.25.40.10 24 87 6.2E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 Gene3D G3DSA:1.25.40.10 627 680 1.5E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 SUPERFAMILY SSF48452 552 779 2.31E-24 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 Pfam PF14559 Tetratricopeptide repeat 180 239 1.1E-7 T 28-03-2018 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 Pfam PF14559 Tetratricopeptide repeat 724 778 1.4E-5 T 28-03-2018 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 Pfam PF14559 Tetratricopeptide repeat 39 82 3.1E-8 T 28-03-2018 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 Pfam PF14559 Tetratricopeptide repeat 110 166 4.0E-7 T 28-03-2018 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 Gene3D G3DSA:1.25.40.10 88 145 7.2E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 Gene3D G3DSA:1.25.40.10 501 561 2.5E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 Gene3D G3DSA:1.25.40.10 438 500 3.8E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 Gene3D G3DSA:1.25.40.10 146 188 3.2E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 Gene3D G3DSA:1.25.40.10 586 626 1.0E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 SUPERFAMILY SSF48452 154 289 2.28E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 SMART SM00028 29 62 22.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 SMART SM00028 748 781 0.041 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 SMART SM00028 576 609 0.0068 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 SMART SM00028 610 643 19.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 SMART SM00028 233 266 150.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 SMART SM00028 301 334 210.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 SMART SM00028 338 371 17.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 SMART SM00028 714 747 77.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 SMART SM00028 97 130 24.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 SMART SM00028 644 677 250.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 SMART SM00028 199 232 270.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 SMART SM00028 542 575 26.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 SMART SM00028 165 198 62.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 SMART SM00028 131 164 5.7 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 SMART SM00028 63 96 26.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 SMART SM00028 508 541 0.097 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 SMART SM00028 372 405 10.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 Gene3D G3DSA:1.25.40.10 562 585 5.7E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 Gene3D G3DSA:1.25.40.10 264 353 2.6E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS10415 532a064a0ddc295296bacfb5a6257358 794 Gene3D G3DSA:1.25.40.10 730 794 2.9E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS11720 cbc9c38cbed4ee9c499917bf0ef1f4d0 202 Gene3D G3DSA:3.40.50.1390 1 111 3.1E-30 T 28-03-2018 MKLM6_RS11720 cbc9c38cbed4ee9c499917bf0ef1f4d0 202 SUPERFAMILY SSF53041 1 142 2.35E-40 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MKLM6_RS11720 cbc9c38cbed4ee9c499917bf0ef1f4d0 202 Gene3D G3DSA:1.20.5.40 112 138 5.8E-18 T 28-03-2018 MKLM6_RS11720 cbc9c38cbed4ee9c499917bf0ef1f4d0 202 Pfam PF00239 Resolvase, N terminal domain 3 143 6.0E-43 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MKLM6_RS11720 cbc9c38cbed4ee9c499917bf0ef1f4d0 202 Gene3D G3DSA:1.10.10.60 139 189 7.3E-6 T 28-03-2018 MKLM6_RS11720 cbc9c38cbed4ee9c499917bf0ef1f4d0 202 SMART SM00857 2 143 2.1E-52 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MKLM6_RS06705 5a01a53739c7ec86467d270a55b9c43a 567 ProSitePatterns PS01120 Urease nickel ligands signature. 127 140 - T 28-03-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MKLM6_RS06705 5a01a53739c7ec86467d270a55b9c43a 567 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 119 1.6E-54 T 28-03-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MKLM6_RS06705 5a01a53739c7ec86467d270a55b9c43a 567 Pfam PF01979 Amidohydrolase family 125 453 1.8E-78 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MKLM6_RS06705 5a01a53739c7ec86467d270a55b9c43a 567 Gene3D G3DSA:3.20.20.140 422 553 1.1E-44 T 28-03-2018 MKLM6_RS06705 5a01a53739c7ec86467d270a55b9c43a 567 Gene3D G3DSA:3.20.20.140 142 421 7.6E-170 T 28-03-2018 MKLM6_RS06705 5a01a53739c7ec86467d270a55b9c43a 567 SUPERFAMILY SSF51338 1 177 1.89E-64 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MKLM6_RS06705 5a01a53739c7ec86467d270a55b9c43a 567 SUPERFAMILY SSF51338 421 477 7.88E-7 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MKLM6_RS06705 5a01a53739c7ec86467d270a55b9c43a 567 Hamap MF_01953 Urease subunit alpha [ureC]. 2 567 57.734 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MKLM6_RS06705 5a01a53739c7ec86467d270a55b9c43a 567 Gene3D G3DSA:2.30.40.10 65 141 1.2E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MKLM6_RS06705 5a01a53739c7ec86467d270a55b9c43a 567 SUPERFAMILY SSF51556 481 567 4.09E-202 T 28-03-2018 IPR032466 Metal-dependent hydrolase MKLM6_RS06705 5a01a53739c7ec86467d270a55b9c43a 567 SUPERFAMILY SSF51556 129 432 4.09E-202 T 28-03-2018 IPR032466 Metal-dependent hydrolase MKLM6_RS06705 5a01a53739c7ec86467d270a55b9c43a 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 295 312 4.9E-35 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MKLM6_RS06705 5a01a53739c7ec86467d270a55b9c43a 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 334 350 4.9E-35 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MKLM6_RS06705 5a01a53739c7ec86467d270a55b9c43a 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 401 416 4.9E-35 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MKLM6_RS06705 5a01a53739c7ec86467d270a55b9c43a 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 427 440 4.9E-35 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MKLM6_RS06705 5a01a53739c7ec86467d270a55b9c43a 567 ProSitePatterns PS00145 Urease active site. 317 333 - T 28-03-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MKLM6_RS06705 5a01a53739c7ec86467d270a55b9c43a 567 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 3 567 1.3E-297 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MKLM6_RS08480 97fe5ce6f8eeb22e8afb1b69dd530ca1 597 SMART SM00332 1 237 6.7E-19 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS08480 97fe5ce6f8eeb22e8afb1b69dd530ca1 597 Pfam PF13672 Protein phosphatase 2C 14 206 7.9E-15 T 28-03-2018 MKLM6_RS08480 97fe5ce6f8eeb22e8afb1b69dd530ca1 597 Gene3D G3DSA:3.60.40.10 2 252 5.9E-35 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS08480 97fe5ce6f8eeb22e8afb1b69dd530ca1 597 Pfam PF00069 Protein kinase domain 283 523 4.5E-32 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MKLM6_RS08480 97fe5ce6f8eeb22e8afb1b69dd530ca1 597 Gene3D G3DSA:1.10.510.10 381 535 3.9E-31 T 28-03-2018 MKLM6_RS08480 97fe5ce6f8eeb22e8afb1b69dd530ca1 597 SUPERFAMILY SSF81606 6 240 9.02E-51 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS08480 97fe5ce6f8eeb22e8afb1b69dd530ca1 597 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 391 403 - T 28-03-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 MKLM6_RS08480 97fe5ce6f8eeb22e8afb1b69dd530ca1 597 Gene3D G3DSA:3.30.200.20 262 380 4.8E-14 T 28-03-2018 MKLM6_RS08480 97fe5ce6f8eeb22e8afb1b69dd530ca1 597 SUPERFAMILY SSF56112 256 533 1.48E-52 T 28-03-2018 IPR011009 Protein kinase-like domain MKLM6_RS08480 97fe5ce6f8eeb22e8afb1b69dd530ca1 597 SMART SM00331 4 239 6.8E-11 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS17320 b113d1f2fecb9e5e1c940b287844a20b 610 SUPERFAMILY SSF49299 420 505 3.53E-22 T 28-03-2018 IPR000601 PKD domain MKLM6_RS17320 b113d1f2fecb9e5e1c940b287844a20b 610 Pfam PF13688 Metallo-peptidase family M12 138 255 1.1E-6 T 28-03-2018 MKLM6_RS17320 b113d1f2fecb9e5e1c940b287844a20b 610 Pfam PF00801 PKD domain 432 493 3.0E-12 T 28-03-2018 IPR000601 PKD domain MKLM6_RS17320 b113d1f2fecb9e5e1c940b287844a20b 610 Gene3D G3DSA:2.60.40.10 506 605 1.5E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS17320 b113d1f2fecb9e5e1c940b287844a20b 610 Gene3D G3DSA:2.60.120.380 278 414 6.5E-8 T 28-03-2018 MKLM6_RS17320 b113d1f2fecb9e5e1c940b287844a20b 610 SMART SM00089 422 504 3.2E-20 T 28-03-2018 IPR022409 PKD/Chitinase domain MKLM6_RS17320 b113d1f2fecb9e5e1c940b287844a20b 610 Gene3D G3DSA:3.40.390.10 135 258 1.4E-8 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 MKLM6_RS17320 b113d1f2fecb9e5e1c940b287844a20b 610 SUPERFAMILY SSF55486 113 251 3.04E-8 T 28-03-2018 MKLM6_RS17320 b113d1f2fecb9e5e1c940b287844a20b 610 Gene3D G3DSA:2.60.40.10 418 505 2.2E-20 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS22420 c08f6bc0c9772fee2ae6ee5366b4a21c 292 Gene3D G3DSA:3.90.260.10 159 240 9.5E-4 T 28-03-2018 IPR002931 Transglutaminase-like MKLM6_RS22420 c08f6bc0c9772fee2ae6ee5366b4a21c 292 SUPERFAMILY SSF54001 109 252 9.67E-19 T 28-03-2018 MKLM6_RS22420 c08f6bc0c9772fee2ae6ee5366b4a21c 292 SMART SM00460 187 251 5.5E-7 T 28-03-2018 IPR002931 Transglutaminase-like MKLM6_RS22420 c08f6bc0c9772fee2ae6ee5366b4a21c 292 Pfam PF01841 Transglutaminase-like superfamily 153 249 5.7E-16 T 28-03-2018 IPR002931 Transglutaminase-like MKLM6_RS14630 df4b6712d9e57808421d1d44e5b0d52e 276 Pfam PF00691 OmpA family 173 267 1.2E-13 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS14630 df4b6712d9e57808421d1d44e5b0d52e 276 PRINTS PR01021 OMPA domain signature 218 234 8.0E-8 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MKLM6_RS14630 df4b6712d9e57808421d1d44e5b0d52e 276 PRINTS PR01021 OMPA domain signature 203 218 8.0E-8 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MKLM6_RS14630 df4b6712d9e57808421d1d44e5b0d52e 276 PRINTS PR01021 OMPA domain signature 174 196 8.0E-8 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MKLM6_RS14630 df4b6712d9e57808421d1d44e5b0d52e 276 SUPERFAMILY SSF103088 166 271 5.62E-26 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS14630 df4b6712d9e57808421d1d44e5b0d52e 276 Gene3D G3DSA:3.30.1330.60 128 276 4.1E-27 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS11035 932ed53b2d161753f6eda069a64fbbde 466 Gene3D G3DSA:3.40.190.10 37 144 1.1E-9 T 28-03-2018 MKLM6_RS11035 932ed53b2d161753f6eda069a64fbbde 466 SUPERFAMILY SSF53850 166 342 5.31E-22 T 28-03-2018 MKLM6_RS11035 932ed53b2d161753f6eda069a64fbbde 466 SUPERFAMILY SSF53850 42 131 5.31E-22 T 28-03-2018 MKLM6_RS11035 932ed53b2d161753f6eda069a64fbbde 466 Pfam PF13379 NMT1-like family 35 314 2.1E-106 T 28-03-2018 MKLM6_RS11035 932ed53b2d161753f6eda069a64fbbde 466 Gene3D G3DSA:3.40.190.10 163 391 2.4E-35 T 28-03-2018 MKLM6_RS12070 c696586d9ce9d6bbf206c3665d6717af 440 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 339 439 3.4E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS12070 c696586d9ce9d6bbf206c3665d6717af 440 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 384 6.1E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS12070 c696586d9ce9d6bbf206c3665d6717af 440 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 419 6.1E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS12070 c696586d9ce9d6bbf206c3665d6717af 440 SUPERFAMILY SSF55874 300 439 2.23E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS12070 c696586d9ce9d6bbf206c3665d6717af 440 SMART SM00387 336 440 2.4E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS12070 c696586d9ce9d6bbf206c3665d6717af 440 Gene3D G3DSA:3.30.565.10 177 440 4.3E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS06885 0e59983907434a130c526199da6ae30a 530 Gene3D G3DSA:3.40.50.300 310 526 1.2E-21 T 28-03-2018 MKLM6_RS06885 0e59983907434a130c526199da6ae30a 530 Pfam PF00488 MutS domain V 353 518 1.9E-25 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MKLM6_RS06885 0e59983907434a130c526199da6ae30a 530 SUPERFAMILY SSF52540 318 524 4.26E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS06885 0e59983907434a130c526199da6ae30a 530 Gene3D G3DSA:1.10.1420.10 34 306 2.5E-11 T 28-03-2018 MKLM6_RS06885 0e59983907434a130c526199da6ae30a 530 SUPERFAMILY SSF48334 42 111 1.07E-7 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 MKLM6_RS06885 0e59983907434a130c526199da6ae30a 530 SMART SM00534 349 528 1.5E-12 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MKLM6_RS12925 d03aab110d42e3e18317a2bc79716ae3 104 Gene3D G3DSA:2.102.10.10 1 104 4.8E-29 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MKLM6_RS12925 d03aab110d42e3e18317a2bc79716ae3 104 Pfam PF00355 Rieske [2Fe-2S] domain 3 90 4.1E-19 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MKLM6_RS12925 d03aab110d42e3e18317a2bc79716ae3 104 SUPERFAMILY SSF50022 2 100 5.76E-31 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 SUPERFAMILY SSF55781 1304 1484 6.76E-26 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 SMART SM00065 1318 1471 2.1E-11 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 Gene3D G3DSA:3.30.450.40 1303 1475 6.3E-29 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 Gene3D G3DSA:3.40.50.300 302 501 4.8E-9 T 28-03-2018 MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 Pfam PF00069 Protein kinase domain 19 271 6.4E-23 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 Pfam PF13185 GAF domain 1317 1462 1.7E-10 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 SMART SM00220 19 281 3.5E-11 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 SUPERFAMILY SSF48452 788 864 2.61E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 SUPERFAMILY SSF48452 942 978 2.61E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 SUPERFAMILY SSF47384 1486 1553 6.87E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 SMART SM00387 1599 1708 1.9E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 Gene3D G3DSA:1.10.510.10 15 288 6.0E-34 T 28-03-2018 MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1669 1687 2.7E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1693 1706 2.7E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1638 1652 2.7E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1656 1666 2.7E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 SMART SM00388 1492 1557 8.4E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 Gene3D G3DSA:3.30.565.10 1552 1708 3.2E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 SUPERFAMILY SSF56112 16 284 5.6E-40 T 28-03-2018 IPR011009 Protein kinase-like domain MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 Gene3D G3DSA:1.25.40.10 736 1300 4.0E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 SUPERFAMILY SSF52540 309 588 4.39E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 Pfam PF13191 AAA ATPase domain 313 499 4.4E-41 T 28-03-2018 MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1492 1551 7.3E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 Gene3D G3DSA:1.10.287.130 1476 1551 1.0E-10 T 28-03-2018 MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1603 1706 9.6E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14710 f169c94264662228686e1cf98c3bcfc6 1708 SUPERFAMILY SSF55874 1552 1707 1.44E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS10620 c4b9b96e411ba0b0b7eabb205171b7fc 363 SUPERFAMILY SSF52540 3 297 4.88E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS10620 c4b9b96e411ba0b0b7eabb205171b7fc 363 Pfam PF06071 Protein of unknown function (DUF933) 279 362 1.8E-39 T 28-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 MKLM6_RS10620 c4b9b96e411ba0b0b7eabb205171b7fc 363 SUPERFAMILY SSF81271 279 360 4.36E-36 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MKLM6_RS10620 c4b9b96e411ba0b0b7eabb205171b7fc 363 Gene3D G3DSA:3.10.20.30 263 362 1.7E-45 T 28-03-2018 IPR012675 Beta-grasp domain MKLM6_RS10620 c4b9b96e411ba0b0b7eabb205171b7fc 363 Pfam PF01926 50S ribosome-binding GTPase 5 126 3.3E-23 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS10620 c4b9b96e411ba0b0b7eabb205171b7fc 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 2.9E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS10620 c4b9b96e411ba0b0b7eabb205171b7fc 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 2.9E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS10620 c4b9b96e411ba0b0b7eabb205171b7fc 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 2.9E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS10620 c4b9b96e411ba0b0b7eabb205171b7fc 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 2.9E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS10620 c4b9b96e411ba0b0b7eabb205171b7fc 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 44.929 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MKLM6_RS10620 c4b9b96e411ba0b0b7eabb205171b7fc 363 Gene3D G3DSA:1.10.150.300 110 200 1.4E-27 T 28-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 MKLM6_RS10620 c4b9b96e411ba0b0b7eabb205171b7fc 363 PIRSF PIRSF006641 1 363 6.2E-157 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MKLM6_RS10620 c4b9b96e411ba0b0b7eabb205171b7fc 363 Gene3D G3DSA:3.40.50.300 1 79 9.1E-9 T 28-03-2018 MKLM6_RS10620 c4b9b96e411ba0b0b7eabb205171b7fc 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 363 1.5E-160 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MKLM6_RS12630 3f2b96a554a111ff98f0677e7525cd75 502 SUPERFAMILY SSF56235 2 257 1.54E-71 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MKLM6_RS12630 3f2b96a554a111ff98f0677e7525cd75 502 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 464 4.8E-159 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MKLM6_RS12630 3f2b96a554a111ff98f0677e7525cd75 502 Gene3D G3DSA:3.60.20.10 2 257 3.4E-53 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MKLM6_RS12630 3f2b96a554a111ff98f0677e7525cd75 502 Pfam PF13522 Glutamine amidotransferase domain 64 208 6.1E-17 T 28-03-2018 MKLM6_RS12630 3f2b96a554a111ff98f0677e7525cd75 502 SUPERFAMILY SSF53271 250 483 6.82E-74 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like MKLM6_RS12630 3f2b96a554a111ff98f0677e7525cd75 502 PIRSF PIRSF000485 1 481 2.3E-164 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MKLM6_RS12630 3f2b96a554a111ff98f0677e7525cd75 502 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 464 45.156 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MKLM6_RS12630 3f2b96a554a111ff98f0677e7525cd75 502 Pfam PF00156 Phosphoribosyl transferase domain 275 393 9.3E-10 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MKLM6_RS12630 3f2b96a554a111ff98f0677e7525cd75 502 Gene3D G3DSA:3.40.50.2020 275 444 1.3E-36 T 28-03-2018 MKLM6_RS05775 42a79f6195cac74c65556dbac93eae94 711 Pfam PF01515 Phosphate acetyl/butaryl transferase 384 700 1.3E-129 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MKLM6_RS05775 42a79f6195cac74c65556dbac93eae94 711 Gene3D G3DSA:3.40.50.300 14 220 1.3E-19 T 28-03-2018 MKLM6_RS05775 42a79f6195cac74c65556dbac93eae94 711 Gene3D G3DSA:3.40.1390.20 221 360 2.5E-32 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like MKLM6_RS05775 42a79f6195cac74c65556dbac93eae94 711 Pfam PF13500 AAA domain 17 198 2.4E-17 T 28-03-2018 MKLM6_RS05775 42a79f6195cac74c65556dbac93eae94 711 Pfam PF07085 DRTGG domain 224 338 1.5E-28 T 28-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MKLM6_RS05775 42a79f6195cac74c65556dbac93eae94 711 SUPERFAMILY SSF53659 383 703 8.15E-94 T 28-03-2018 MKLM6_RS05775 42a79f6195cac74c65556dbac93eae94 711 SUPERFAMILY SSF75138 219 339 4.71E-26 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like MKLM6_RS05775 42a79f6195cac74c65556dbac93eae94 711 Gene3D G3DSA:3.40.50.10750 523 676 1.2E-64 T 28-03-2018 MKLM6_RS05775 42a79f6195cac74c65556dbac93eae94 711 PIRSF PIRSF006107 14 708 4.2E-172 T 28-03-2018 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MKLM6_RS05775 42a79f6195cac74c65556dbac93eae94 711 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 399 700 2.7E-125 T 28-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MKLM6_RS05775 42a79f6195cac74c65556dbac93eae94 711 SUPERFAMILY SSF52540 18 230 4.35E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS08670 ed98e299cac18cdb02ed7520fc5ddcbc 237 PRINTS PR00111 Alpha/beta hydrolase fold signature 76 89 7.4E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS08670 ed98e299cac18cdb02ed7520fc5ddcbc 237 PRINTS PR00111 Alpha/beta hydrolase fold signature 22 37 7.4E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS08670 ed98e299cac18cdb02ed7520fc5ddcbc 237 PRINTS PR00111 Alpha/beta hydrolase fold signature 183 197 7.4E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS08670 ed98e299cac18cdb02ed7520fc5ddcbc 237 Gene3D G3DSA:3.40.50.1820 1 235 1.8E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS08670 ed98e299cac18cdb02ed7520fc5ddcbc 237 SUPERFAMILY SSF53474 1 233 5.05E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS08670 ed98e299cac18cdb02ed7520fc5ddcbc 237 Pfam PF12697 Alpha/beta hydrolase family 1 231 8.6E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS08670 ed98e299cac18cdb02ed7520fc5ddcbc 237 TIGRFAM TIGR01738 bioH: pimelyl-[acyl-carrier protein] methyl ester esterase 1 233 4.1E-64 T 28-03-2018 IPR010076 Pimeloyl-[acyl-carrier protein] methyl ester esterase GO:0009102|GO:0052689 KEGG: 00780+3.1.1.85|MetaCyc: PWY-6519 MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 Pfam PF08448 PAS fold 263 376 2.3E-11 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 Pfam PF08448 PAS fold 394 503 3.0E-21 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 SUPERFAMILY SSF55073 765 922 3.06E-53 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 Pfam PF08447 PAS fold 538 619 5.5E-14 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 Gene3D G3DSA:3.30.70.270 757 924 3.6E-63 T 28-03-2018 MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 758 919 3.1E-45 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 SMART SM00052 931 1178 2.3E-104 T 28-03-2018 IPR001633 EAL domain MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 SUPERFAMILY SSF55785 243 373 1.33E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 Gene3D G3DSA:3.30.450.20 375 504 3.6E-31 T 28-03-2018 MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 Gene3D G3DSA:3.30.450.20 505 633 6.3E-38 T 28-03-2018 MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 SUPERFAMILY SSF55785 641 747 1.53E-27 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 SMART SM00267 749 921 1.5E-70 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 Gene3D G3DSA:3.20.20.450 925 1188 5.1E-92 T 28-03-2018 IPR001633 EAL domain MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 SMART SM00091 513 579 1.5E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 SMART SM00091 256 321 0.0021 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 SMART SM00091 635 701 1.5E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 SMART SM00091 387 453 4.2E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 Pfam PF00563 EAL domain 938 1173 3.0E-70 T 28-03-2018 IPR001633 EAL domain MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 Pfam PF00672 HAMP domain 201 245 9.1E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 510 634 1.0E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 253 381 1.3E-8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 640 755 7.4E-19 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 384 508 3.6E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 SUPERFAMILY SSF55785 372 499 9.07E-26 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 Gene3D G3DSA:3.30.450.20 235 374 9.1E-23 T 28-03-2018 MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 SMART SM00086 707 749 0.0097 T 28-03-2018 IPR001610 PAC motif MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 SMART SM00086 333 375 0.088 T 28-03-2018 IPR001610 PAC motif MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 SMART SM00086 460 501 0.41 T 28-03-2018 IPR001610 PAC motif MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 SMART SM00086 585 627 2.4E-5 T 28-03-2018 IPR001610 PAC motif MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 SUPERFAMILY SSF55785 498 625 2.26E-27 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 SUPERFAMILY SSF141868 937 1185 1.01E-83 T 28-03-2018 IPR001633 EAL domain MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 Gene3D G3DSA:3.40.50.10600 634 756 9.2E-26 T 28-03-2018 MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 Pfam PF00990 Diguanylate cyclase, GGDEF domain 760 916 6.3E-53 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 SUPERFAMILY SSF158472 198 246 9.29E-7 T 28-03-2018 MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 Gene3D G3DSA:3.30.450.20 26 168 0.0022 T 28-03-2018 MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 Pfam PF13426 PAS domain 646 748 1.8E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09175 38c7aa7c36df126cc08253b767f1bbdc 1189 SMART SM00304 197 249 7.6E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS13565 c190c0ead60d6cc5a79fe42400951cd3 877 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 382 534 1.1E-33 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MKLM6_RS13565 c190c0ead60d6cc5a79fe42400951cd3 877 Pfam PF11987 Translation-initiation factor 2 663 767 2.6E-32 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 MKLM6_RS13565 c190c0ead60d6cc5a79fe42400951cd3 877 SUPERFAMILY SSF52540 374 549 1.1E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS13565 c190c0ead60d6cc5a79fe42400951cd3 877 Gene3D G3DSA:3.40.50.10050 681 756 2.0E-23 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 MKLM6_RS13565 c190c0ead60d6cc5a79fe42400951cd3 877 SUPERFAMILY SSF46955 3 51 1.34E-8 T 28-03-2018 IPR009061 Putative DNA-binding domain MKLM6_RS13565 c190c0ead60d6cc5a79fe42400951cd3 877 Pfam PF00009 Elongation factor Tu GTP binding domain 381 538 1.2E-34 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS13565 c190c0ead60d6cc5a79fe42400951cd3 877 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 66 105 2.8E-11 T 28-03-2018 IPR013575 Initiation factor 2 associated domain, bacterial MKLM6_RS13565 c190c0ead60d6cc5a79fe42400951cd3 877 SUPERFAMILY SSF50447 550 632 6.19E-23 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain MKLM6_RS13565 c190c0ead60d6cc5a79fe42400951cd3 877 Gene3D G3DSA:2.40.30.10 778 876 1.3E-27 T 28-03-2018 MKLM6_RS13565 c190c0ead60d6cc5a79fe42400951cd3 877 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 875 17.09 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MKLM6_RS13565 c190c0ead60d6cc5a79fe42400951cd3 877 Gene3D G3DSA:2.40.30.10 552 680 2.3E-28 T 28-03-2018 MKLM6_RS13565 c190c0ead60d6cc5a79fe42400951cd3 877 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 298 349 8.5E-17 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal MKLM6_RS13565 c190c0ead60d6cc5a79fe42400951cd3 877 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 51 1.3E-7 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal MKLM6_RS13565 c190c0ead60d6cc5a79fe42400951cd3 877 Gene3D G3DSA:3.30.56.50 301 342 1.1E-11 T 28-03-2018 MKLM6_RS13565 c190c0ead60d6cc5a79fe42400951cd3 877 Gene3D G3DSA:3.30.56.50 4 46 2.1E-8 T 28-03-2018 MKLM6_RS13565 c190c0ead60d6cc5a79fe42400951cd3 877 ProSitePatterns PS01176 Initiation factor 2 signature. 828 850 - T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MKLM6_RS13565 c190c0ead60d6cc5a79fe42400951cd3 877 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 294 876 7.1E-257 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MKLM6_RS13565 c190c0ead60d6cc5a79fe42400951cd3 877 SUPERFAMILY SSF52156 658 784 4.32E-33 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 MKLM6_RS13565 c190c0ead60d6cc5a79fe42400951cd3 877 Gene3D G3DSA:3.40.50.300 372 551 3.8E-40 T 28-03-2018 MKLM6_RS13565 c190c0ead60d6cc5a79fe42400951cd3 877 SUPERFAMILY SSF50447 779 875 1.85E-33 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain MKLM6_RS04850 c6c2e84cd164de8159a16ea98836e0ee 451 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 429 5.2E-170 T 28-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 MKLM6_RS04850 c6c2e84cd164de8159a16ea98836e0ee 451 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 439 33.433 T 28-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 MKLM6_RS04850 c6c2e84cd164de8159a16ea98836e0ee 451 Gene3D G3DSA:3.40.50.300 92 297 4.3E-39 T 28-03-2018 MKLM6_RS04850 c6c2e84cd164de8159a16ea98836e0ee 451 SUPERFAMILY SSF47446 329 430 8.18E-33 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MKLM6_RS04850 c6c2e84cd164de8159a16ea98836e0ee 451 Gene3D G3DSA:1.10.260.30 328 432 5.9E-34 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MKLM6_RS04850 c6c2e84cd164de8159a16ea98836e0ee 451 Gene3D G3DSA:1.20.120.140 1 91 9.0E-30 T 28-03-2018 MKLM6_RS04850 c6c2e84cd164de8159a16ea98836e0ee 451 SMART SM00382 99 301 3.5E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS04850 c6c2e84cd164de8159a16ea98836e0ee 451 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 269 282 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MKLM6_RS04850 c6c2e84cd164de8159a16ea98836e0ee 451 Pfam PF02978 Signal peptide binding domain 329 427 1.1E-28 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MKLM6_RS04850 c6c2e84cd164de8159a16ea98836e0ee 451 SMART SM00962 100 296 6.2E-114 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MKLM6_RS04850 c6c2e84cd164de8159a16ea98836e0ee 451 SUPERFAMILY SSF52540 42 353 1.39E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS04850 c6c2e84cd164de8159a16ea98836e0ee 451 SMART SM00963 1 86 4.6E-37 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MKLM6_RS04850 c6c2e84cd164de8159a16ea98836e0ee 451 Pfam PF00448 SRP54-type protein, GTPase domain 101 296 1.9E-73 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MKLM6_RS04850 c6c2e84cd164de8159a16ea98836e0ee 451 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 9.1E-21 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 Gene3D G3DSA:3.30.70.100 386 429 0.02 T 28-03-2018 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 SUPERFAMILY SSF48452 253 454 6.64E-30 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 Gene3D G3DSA:1.20.1250.10 185 237 8.7E-17 T 28-03-2018 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 Pfam PF12770 CHAT domain 637 932 2.2E-57 T 28-03-2018 IPR024983 CHAT domain MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 Gene3D G3DSA:1.25.40.10 53 123 2.6E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 Pfam PF13424 Tetratricopeptide repeat 133 203 6.0E-17 T 28-03-2018 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 Pfam PF13424 Tetratricopeptide repeat 338 407 1.4E-13 T 28-03-2018 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 Pfam PF13424 Tetratricopeptide repeat 215 287 1.1E-18 T 28-03-2018 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 Gene3D G3DSA:3.40.50.1460 635 933 1.3E-34 T 28-03-2018 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 SMART SM00028 376 409 12.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 SMART SM00028 296 329 3.4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 SMART SM00028 336 369 5.4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 SMART SM00028 216 249 0.0049 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 SMART SM00028 55 88 0.74 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 SMART SM00028 134 167 0.0093 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 SMART SM00028 256 289 3.6E-6 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 SMART SM00028 95 128 11.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 SMART SM00028 174 207 7.3E-5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 Pfam PF13374 Tetratricopeptide repeat 295 329 1.8E-4 T 28-03-2018 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 Gene3D G3DSA:1.10.150.200 260 304 1.1E-14 T 28-03-2018 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 Gene3D G3DSA:1.10.150.200 124 184 2.9E-15 T 28-03-2018 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 Gene3D G3DSA:1.10.150.200 345 385 2.4E-8 T 28-03-2018 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 Gene3D G3DSA:1.10.150.200 305 344 3.4E-9 T 28-03-2018 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 SUPERFAMILY SSF48452 55 287 3.03E-22 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS17715 98bf4d6b7687d4779643d3372ab29388 934 Gene3D G3DSA:1.20.5.1140 238 259 1.3E-4 T 28-03-2018 MKLM6_RS06940 d1158b17d9ac37adacff48fa70f71cb1 483 SUPERFAMILY SSF158472 188 237 1.57E-7 T 28-03-2018 MKLM6_RS06940 d1158b17d9ac37adacff48fa70f71cb1 483 Gene3D G3DSA:3.30.70.270 359 483 1.2E-40 T 28-03-2018 MKLM6_RS06940 d1158b17d9ac37adacff48fa70f71cb1 483 SUPERFAMILY SSF103190 45 156 3.06E-10 T 28-03-2018 IPR029151 Periplasmic sensor domain-like MKLM6_RS06940 d1158b17d9ac37adacff48fa70f71cb1 483 SUPERFAMILY SSF55785 254 363 1.11E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS06940 d1158b17d9ac37adacff48fa70f71cb1 483 SMART SM00267 355 481 2.8E-22 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS06940 d1158b17d9ac37adacff48fa70f71cb1 483 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 237 361 2.1E-21 T 28-03-2018 IPR000014 PAS domain MKLM6_RS06940 d1158b17d9ac37adacff48fa70f71cb1 483 SUPERFAMILY SSF55073 371 471 1.1E-31 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS06940 d1158b17d9ac37adacff48fa70f71cb1 483 Pfam PF17203 Single cache domain 3 46 163 7.4E-21 T 28-03-2018 IPR033463 Single cache domain 3 MKLM6_RS06940 d1158b17d9ac37adacff48fa70f71cb1 483 Pfam PF00672 HAMP domain 188 236 1.2E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS06940 d1158b17d9ac37adacff48fa70f71cb1 483 SMART SM00304 188 240 3.4E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS06940 d1158b17d9ac37adacff48fa70f71cb1 483 SMART SM00091 240 306 2.3E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS06940 d1158b17d9ac37adacff48fa70f71cb1 483 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 364 458 1.6E-32 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS06940 d1158b17d9ac37adacff48fa70f71cb1 483 Pfam PF00990 Diguanylate cyclase, GGDEF domain 366 464 3.5E-35 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS06940 d1158b17d9ac37adacff48fa70f71cb1 483 Gene3D G3DSA:3.30.450.20 33 153 3.4E-4 T 28-03-2018 MKLM6_RS06940 d1158b17d9ac37adacff48fa70f71cb1 483 Pfam PF08447 PAS fold 264 345 9.0E-9 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS06940 d1158b17d9ac37adacff48fa70f71cb1 483 Gene3D G3DSA:3.30.450.20 213 358 1.2E-23 T 28-03-2018 MKLM6_RS07730 2348cd2ecaecb7aace2aafdd0e32cc59 282 Pfam PF04909 Amidohydrolase 58 269 1.0E-26 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MKLM6_RS07730 2348cd2ecaecb7aace2aafdd0e32cc59 282 Gene3D G3DSA:3.20.20.140 4 276 4.4E-40 T 28-03-2018 MKLM6_RS07730 2348cd2ecaecb7aace2aafdd0e32cc59 282 SUPERFAMILY SSF51556 5 44 2.18E-43 T 28-03-2018 IPR032466 Metal-dependent hydrolase MKLM6_RS07730 2348cd2ecaecb7aace2aafdd0e32cc59 282 SUPERFAMILY SSF51556 82 274 2.18E-43 T 28-03-2018 IPR032466 Metal-dependent hydrolase MKLM6_RS19010 a90ebf2e731dcf86225191fdd748b609 179 Pfam PF00072 Response regulator receiver domain 8 116 7.0E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS19010 a90ebf2e731dcf86225191fdd748b609 179 Gene3D G3DSA:3.40.50.2300 1 160 3.3E-29 T 28-03-2018 MKLM6_RS19010 a90ebf2e731dcf86225191fdd748b609 179 SUPERFAMILY SSF52172 4 140 3.98E-31 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS19010 a90ebf2e731dcf86225191fdd748b609 179 SMART SM00448 6 116 1.3E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS08595 e3f0f350dd5972a530cec8effad562b5 394 Gene3D G3DSA:3.40.50.300 14 351 2.4E-5 T 28-03-2018 MKLM6_RS08595 e3f0f350dd5972a530cec8effad562b5 394 SUPERFAMILY SSF52540 4 291 1.36E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS03510 8d4995bb5af2f46cc5756c51031510f5 522 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 7 442 6.3E-182 T 28-03-2018 IPR010232 Probable protein kinase UbiB GO:0006744 MKLM6_RS03510 8d4995bb5af2f46cc5756c51031510f5 522 Pfam PF03109 ABC1 family 112 231 9.9E-38 T 28-03-2018 IPR004147 UbiB domain MKLM6_RS03510 8d4995bb5af2f46cc5756c51031510f5 522 Hamap MF_00414 Probable protein kinase UbiB [ubiB]. 4 518 50.534 T 28-03-2018 IPR010232 Probable protein kinase UbiB GO:0006744 MKLM6_RS03510 8d4995bb5af2f46cc5756c51031510f5 522 Gene3D G3DSA:1.10.510.10 270 503 0.0045 T 28-03-2018 MKLM6_RS03510 8d4995bb5af2f46cc5756c51031510f5 522 SUPERFAMILY SSF56112 193 432 1.23E-48 T 28-03-2018 IPR011009 Protein kinase-like domain MKLM6_RS03510 8d4995bb5af2f46cc5756c51031510f5 522 SUPERFAMILY SSF56112 95 158 1.23E-48 T 28-03-2018 IPR011009 Protein kinase-like domain MKLM6_RS03510 8d4995bb5af2f46cc5756c51031510f5 522 Gene3D G3DSA:3.30.200.20 102 244 1.4E-24 T 28-03-2018 MKLM6_RS18075 c5cabca44c58b92731ef4bf0bc2d67f0 925 SUPERFAMILY SSF53067 23 214 6.04E-29 T 28-03-2018 MKLM6_RS18075 c5cabca44c58b92731ef4bf0bc2d67f0 925 SUPERFAMILY SSF53067 227 348 9.43E-21 T 28-03-2018 MKLM6_RS18075 c5cabca44c58b92731ef4bf0bc2d67f0 925 SUPERFAMILY SSF53067 387 461 9.43E-21 T 28-03-2018 MKLM6_RS18075 c5cabca44c58b92731ef4bf0bc2d67f0 925 Pfam PF00012 Hsp70 protein 24 312 6.6E-17 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MKLM6_RS18075 c5cabca44c58b92731ef4bf0bc2d67f0 925 Gene3D G3DSA:3.30.420.40 20 235 8.0E-33 T 28-03-2018 MKLM6_RS18075 c5cabca44c58b92731ef4bf0bc2d67f0 925 Pfam PF12531 DNA-K related protein 677 924 2.6E-108 T 28-03-2018 IPR021030 Protein of unknown function DUF3731 MKLM6_RS18075 c5cabca44c58b92731ef4bf0bc2d67f0 925 PRINTS PR00301 70kDa heat shock protein signature 22 35 1.3E-8 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MKLM6_RS18075 c5cabca44c58b92731ef4bf0bc2d67f0 925 PRINTS PR00301 70kDa heat shock protein signature 171 191 1.3E-8 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MKLM6_RS18075 c5cabca44c58b92731ef4bf0bc2d67f0 925 PRINTS PR00301 70kDa heat shock protein signature 238 248 1.3E-8 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MKLM6_RS18075 c5cabca44c58b92731ef4bf0bc2d67f0 925 Gene3D G3DSA:3.30.420.40 236 434 2.8E-17 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1084 1193 4.4E-10 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Gene3D G3DSA:1.10.1200.10 609 707 8.4E-16 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SUPERFAMILY SSF52151 1422 1513 6.8E-65 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SUPERFAMILY SSF52151 1229 1359 6.8E-65 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Gene3D G3DSA:1.10.1200.10 3617 3692 2.5E-20 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Gene3D G3DSA:3.30.300.30 482 590 2.9E-15 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3135 3526 7.2E-128 T 28-03-2018 IPR010071 Amino acid adenylation domain MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Gene3D G3DSA:3.40.47.10 972 1131 7.2E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Gene3D G3DSA:3.40.47.10 708 969 8.2E-76 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Gene3D G3DSA:1.10.1200.10 1575 1667 1.5E-11 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3252 3263 - T 28-03-2018 IPR020845 AMP-binding, conserved site MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SUPERFAMILY SSF47336 1677 1768 1.83E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Gene3D G3DSA:3.90.1150.10 2183 2301 1.2E-11 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Gene3D G3DSA:3.30.559.10 2651 2857 4.3E-28 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Gene3D G3DSA:3.90.1150.10 1860 2025 9.1E-33 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Pfam PF00698 Acyl transferase domain 1231 1508 1.2E-53 T 28-03-2018 IPR014043 Acyl transferase MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SUPERFAMILY SSF56801 395 593 3.79E-104 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SUPERFAMILY SSF56801 23 360 3.79E-104 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Pfam PF00501 AMP-binding enzyme 29 489 1.6E-82 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Pfam PF00501 AMP-binding enzyme 3115 3502 2.0E-94 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SUPERFAMILY SSF56801 3089 3623 3.92E-151 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SUPERFAMILY SSF47336 623 728 3.01E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 2100 2136 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Pfam PF00202 Aminotransferase class-III 1899 2268 2.6E-52 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SMART SM00823 Phosphopantetheine attachment site 1589 1661 0.001 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SMART SM00823 Phosphopantetheine attachment site 3611 3680 0.0011 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SMART SM00823 Phosphopantetheine attachment site 628 700 1.6E-14 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SMART SM00823 Phosphopantetheine attachment site 1679 1751 5.3E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Gene3D G3DSA:3.40.640.10 2032 2182 6.2E-37 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Pfam PF00550 Phosphopantetheine attachment site 3613 3676 1.1E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Pfam PF00550 Phosphopantetheine attachment site 629 696 3.4E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Pfam PF00550 Phosphopantetheine attachment site 1592 1657 4.9E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Pfam PF00550 Phosphopantetheine attachment site 1681 1744 3.6E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Gene3D G3DSA:2.30.38.10 398 481 4.1E-21 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 715 955 3.1E-79 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 965 1080 5.9E-41 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SUPERFAMILY SSF47336 3605 3676 9.81E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1705 1720 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1232 1527 1.3E-86 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Pfam PF13193 AMP-binding enzyme C-terminal domain 3510 3581 3.1E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Gene3D G3DSA:3.40.50.980 22 190 2.0E-26 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Gene3D G3DSA:3.30.70.250 1372 1413 5.8E-13 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SUPERFAMILY SSF53901 1108 1130 1.03E-91 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SUPERFAMILY SSF53901 712 1073 1.03E-91 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Gene3D G3DSA:1.10.1200.10 1669 1790 4.2E-11 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SUPERFAMILY SSF47336 1590 1661 4.32E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Gene3D G3DSA:3.40.366.10 1414 1526 1.5E-20 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Pfam PF00668 Condensation domain 2662 3097 4.8E-77 T 28-03-2018 IPR001242 Condensation domain MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SUPERFAMILY SSF53335 2421 2642 1.17E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Pfam PF08242 Methyltransferase domain 2486 2586 7.0E-20 T 28-03-2018 IPR013217 Methyltransferase type 12 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Gene3D G3DSA:3.40.366.10 1225 1371 3.7E-42 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SMART SM01294 1590 1657 3.0E-4 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SMART SM01294 629 696 1.8E-6 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Gene3D G3DSA:3.30.300.30 3497 3616 5.4E-34 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Gene3D G3DSA:2.30.38.10 3410 3492 9.5E-24 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 ProSitePatterns PS00455 Putative AMP-binding domain signature. 186 197 - T 28-03-2018 IPR020845 AMP-binding, conserved site MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Gene3D G3DSA:3.40.50.150 2400 2650 5.9E-26 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SUPERFAMILY SSF53383 1871 2293 1.29E-87 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 870 886 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SUPERFAMILY SSF52777 2661 2854 8.89E-32 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SMART SM00825 Beta-ketoacyl synthase 716 1133 3.0E-174 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Gene3D G3DSA:3.40.50.980 191 361 1.4E-33 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Gene3D G3DSA:3.40.50.980 3258 3407 8.9E-34 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SUPERFAMILY SSF52777 2842 3085 4.45E-49 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 Gene3D G3DSA:3.40.50.980 3105 3257 7.4E-50 T 28-03-2018 MKLM6_RS12295 369fff90d63821f04a3d3adf4c377e48 3704 SUPERFAMILY SSF55048 1358 1420 5.89E-8 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 MKLM6_RS20690 cb5630b62821e4993309b8f48f0cbe5c 656 Pfam PF01841 Transglutaminase-like superfamily 289 362 3.1E-5 T 28-03-2018 IPR002931 Transglutaminase-like MKLM6_RS20690 cb5630b62821e4993309b8f48f0cbe5c 656 SUPERFAMILY SSF54001 285 429 9.16E-8 T 28-03-2018 MKLM6_RS20690 cb5630b62821e4993309b8f48f0cbe5c 656 Pfam PF12969 Domain of Unknown Function with PDB structure (DUF3857) 81 207 2.1E-12 T 28-03-2018 IPR024618 Domain of unknown function DUF3857 MKLM6_RS13780 04399da5bf9123fa2f1aa19cf1f8834c 343 SUPERFAMILY SSF55347 149 311 1.2E-48 T 28-03-2018 MKLM6_RS13780 04399da5bf9123fa2f1aa19cf1f8834c 343 SMART SM00859 3 141 2.1E-57 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MKLM6_RS13780 04399da5bf9123fa2f1aa19cf1f8834c 343 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 160 314 4.7E-15 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MKLM6_RS13780 04399da5bf9123fa2f1aa19cf1f8834c 343 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 144 160 - T 28-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MKLM6_RS13780 04399da5bf9123fa2f1aa19cf1f8834c 343 Gene3D G3DSA:3.30.360.10 159 311 4.8E-57 T 28-03-2018 MKLM6_RS13780 04399da5bf9123fa2f1aa19cf1f8834c 343 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 3 343 1.3E-129 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MKLM6_RS13780 04399da5bf9123fa2f1aa19cf1f8834c 343 Gene3D G3DSA:3.40.50.720 1 158 3.0E-45 T 28-03-2018 MKLM6_RS13780 04399da5bf9123fa2f1aa19cf1f8834c 343 SUPERFAMILY SSF51735 3 173 3.19E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS13780 04399da5bf9123fa2f1aa19cf1f8834c 343 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 337 41.75 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MKLM6_RS13780 04399da5bf9123fa2f1aa19cf1f8834c 343 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 141 4.4E-36 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MKLM6_RS20980 359b34697ebf01a72348448eac1cf84f 168 Gene3D G3DSA:1.10.10.10 77 167 7.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS20980 359b34697ebf01a72348448eac1cf84f 168 Pfam PF04542 Sigma-70 region 2 14 78 1.6E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS20980 359b34697ebf01a72348448eac1cf84f 168 SUPERFAMILY SSF88659 82 164 9.81E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS20980 359b34697ebf01a72348448eac1cf84f 168 Pfam PF08281 Sigma-70, region 4 110 161 1.0E-17 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS20980 359b34697ebf01a72348448eac1cf84f 168 Gene3D G3DSA:1.10.1740.10 5 76 1.2E-13 T 28-03-2018 MKLM6_RS20980 359b34697ebf01a72348448eac1cf84f 168 SUPERFAMILY SSF88946 13 91 6.28E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS20980 359b34697ebf01a72348448eac1cf84f 168 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 164 1.8E-25 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11955 0059da357ac6fc6d86bd9f97086865cd 304 Pfam PF00005 ABC transporter 17 160 3.3E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS11955 0059da357ac6fc6d86bd9f97086865cd 304 SMART SM00382 26 209 1.4E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS11955 0059da357ac6fc6d86bd9f97086865cd 304 Gene3D G3DSA:3.40.50.300 1 245 1.3E-60 T 28-03-2018 MKLM6_RS11955 0059da357ac6fc6d86bd9f97086865cd 304 SUPERFAMILY SSF52540 2 216 5.12E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS05860 16814da3ed38a183bfe9bbb0e28832f0 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 62 4.8E-14 T 28-03-2018 IPR013185 Translation elongation factor, KOW-like MKLM6_RS05860 16814da3ed38a183bfe9bbb0e28832f0 188 Gene3D G3DSA:2.40.50.140 68 129 3.5E-18 T 28-03-2018 MKLM6_RS05860 16814da3ed38a183bfe9bbb0e28832f0 188 Hamap MF_00646 Elongation factor P-like protein [yeiP]. 2 188 38.751 T 28-03-2018 IPR011897 Translation elongation factor P-like, YeiP MKLM6_RS05860 16814da3ed38a183bfe9bbb0e28832f0 188 SUPERFAMILY SSF50249 69 130 3.0E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS05860 16814da3ed38a183bfe9bbb0e28832f0 188 SMART SM01185 69 124 2.3E-17 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 MKLM6_RS05860 16814da3ed38a183bfe9bbb0e28832f0 188 SMART SM00841 132 187 1.3E-25 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 MKLM6_RS05860 16814da3ed38a183bfe9bbb0e28832f0 188 Pfam PF09285 Elongation factor P, C-terminal 132 187 1.0E-20 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 MKLM6_RS05860 16814da3ed38a183bfe9bbb0e28832f0 188 PIRSF PIRSF005901 1 188 1.9E-64 T 28-03-2018 IPR020599 Translation elongation factor P/YeiP MKLM6_RS05860 16814da3ed38a183bfe9bbb0e28832f0 188 Gene3D G3DSA:2.30.30.30 2 63 7.8E-14 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 MKLM6_RS05860 16814da3ed38a183bfe9bbb0e28832f0 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 72 124 1.4E-15 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 MKLM6_RS05860 16814da3ed38a183bfe9bbb0e28832f0 188 SUPERFAMILY SSF50249 131 188 1.56E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS05860 16814da3ed38a183bfe9bbb0e28832f0 188 Gene3D G3DSA:2.40.50.140 132 187 1.4E-21 T 28-03-2018 MKLM6_RS05860 16814da3ed38a183bfe9bbb0e28832f0 188 SUPERFAMILY SSF50104 3 64 1.2E-8 T 28-03-2018 IPR008991 Translation protein SH3-like domain MKLM6_RS15315 39090a78fb1ae97734d2dd4e9d4e93b5 158 Pfam PF00114 Pilin (bacterial filament) 40 157 1.9E-4 T 28-03-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 MKLM6_RS15315 39090a78fb1ae97734d2dd4e9d4e93b5 158 SUPERFAMILY SSF54523 12 102 4.34E-19 T 28-03-2018 MKLM6_RS15315 39090a78fb1ae97734d2dd4e9d4e93b5 158 Gene3D G3DSA:3.30.700.10 12 157 1.2E-22 T 28-03-2018 MKLM6_RS15315 39090a78fb1ae97734d2dd4e9d4e93b5 158 Pfam PF07963 Prokaryotic N-terminal methylation motif 7 31 7.9E-11 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS15315 39090a78fb1ae97734d2dd4e9d4e93b5 158 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 32 1.8E-10 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS15315 39090a78fb1ae97734d2dd4e9d4e93b5 158 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS18080 bccae762921bab48a29c08771a4f653a 443 Gene3D G3DSA:1.20.1600.10 17 427 1.6E-60 T 28-03-2018 MKLM6_RS18080 bccae762921bab48a29c08771a4f653a 443 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 21 434 8.9E-81 T 28-03-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 MKLM6_RS18080 bccae762921bab48a29c08771a4f653a 443 Pfam PF02321 Outer membrane efflux protein 234 420 4.3E-27 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS18080 bccae762921bab48a29c08771a4f653a 443 Pfam PF02321 Outer membrane efflux protein 25 212 4.8E-21 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS18080 bccae762921bab48a29c08771a4f653a 443 SUPERFAMILY SSF56954 24 437 1.96E-73 T 28-03-2018 MKLM6_RS16005 5302f18e2a767d4c51f25a5d668767e9 888 Gene3D G3DSA:3.40.50.300 465 733 1.5E-4 T 28-03-2018 MKLM6_RS16005 5302f18e2a767d4c51f25a5d668767e9 888 SUPERFAMILY SSF53756 5 413 1.07E-18 T 28-03-2018 MKLM6_RS16005 5302f18e2a767d4c51f25a5d668767e9 888 Pfam PF00534 Glycosyl transferases group 1 280 354 1.8E-7 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 MKLM6_RS16005 5302f18e2a767d4c51f25a5d668767e9 888 SUPERFAMILY SSF52540 481 593 8.59E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS16005 5302f18e2a767d4c51f25a5d668767e9 888 Gene3D G3DSA:3.40.50.2000 190 400 1.8E-15 T 28-03-2018 MKLM6_RS19875 bd7658ff8c256f8366972a29faec1bf6 84 Pfam PF03776 Septum formation topological specificity factor MinE 14 81 5.3E-23 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 MKLM6_RS19875 bd7658ff8c256f8366972a29faec1bf6 84 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 84 18.325 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 MKLM6_RS19875 bd7658ff8c256f8366972a29faec1bf6 84 SUPERFAMILY SSF55229 33 83 4.71E-15 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 MKLM6_RS19875 bd7658ff8c256f8366972a29faec1bf6 84 Gene3D G3DSA:3.30.1070.10 1 82 1.3E-26 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 MKLM6_RS19875 bd7658ff8c256f8366972a29faec1bf6 84 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 82 2.8E-30 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 MKLM6_RS22505 dbfbcad03c0d7e87423dee96a948463d 316 Pfam PF01343 Peptidase family S49 129 270 9.0E-33 T 28-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 MKLM6_RS22505 dbfbcad03c0d7e87423dee96a948463d 316 Gene3D G3DSA:3.90.226.10 46 291 8.9E-35 T 28-03-2018 MKLM6_RS22505 dbfbcad03c0d7e87423dee96a948463d 316 SUPERFAMILY SSF52096 202 263 1.05E-40 T 28-03-2018 IPR029045 ClpP/crotonase-like domain MKLM6_RS22505 dbfbcad03c0d7e87423dee96a948463d 316 SUPERFAMILY SSF52096 47 173 1.05E-40 T 28-03-2018 IPR029045 ClpP/crotonase-like domain MKLM6_RS16960 07797b968c4deaee57c1ccc451ef940d 91 SUPERFAMILY SSF51182 14 89 2.6E-13 T 28-03-2018 IPR011051 RmlC-like cupin domain MKLM6_RS16960 07797b968c4deaee57c1ccc451ef940d 91 Gene3D G3DSA:2.60.120.10 2 90 9.5E-14 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS16960 07797b968c4deaee57c1ccc451ef940d 91 Pfam PF05899 Protein of unknown function (DUF861) 16 88 1.8E-23 T 28-03-2018 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 MKLM6_RS16880 b997d20a9ab4d55f4e874b159480f9b5 453 SUPERFAMILY SSF52172 7 189 5.27E-42 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS16880 b997d20a9ab4d55f4e874b159480f9b5 453 SUPERFAMILY SSF52540 145 383 1.64E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS16880 b997d20a9ab4d55f4e874b159480f9b5 453 Pfam PF00072 Response regulator receiver domain 8 118 1.8E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS16880 b997d20a9ab4d55f4e874b159480f9b5 453 Gene3D G3DSA:1.10.8.60 312 408 3.9E-18 T 28-03-2018 MKLM6_RS16880 b997d20a9ab4d55f4e874b159480f9b5 453 SUPERFAMILY SSF46689 352 451 9.41E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS16880 b997d20a9ab4d55f4e874b159480f9b5 453 SMART SM00382 164 302 1.7E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS16880 b997d20a9ab4d55f4e874b159480f9b5 453 SMART SM00448 6 118 4.3E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS16880 b997d20a9ab4d55f4e874b159480f9b5 453 Gene3D G3DSA:3.40.50.2300 1 141 1.8E-34 T 28-03-2018 MKLM6_RS16880 b997d20a9ab4d55f4e874b159480f9b5 453 Pfam PF00158 Sigma-54 interaction domain 145 305 5.4E-42 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MKLM6_RS16880 b997d20a9ab4d55f4e874b159480f9b5 453 Gene3D G3DSA:1.10.10.60 409 453 1.6E-9 T 28-03-2018 MKLM6_RS16880 b997d20a9ab4d55f4e874b159480f9b5 453 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 352 361 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site MKLM6_RS16880 b997d20a9ab4d55f4e874b159480f9b5 453 Gene3D G3DSA:3.40.50.300 142 311 1.9E-21 T 28-03-2018 MKLM6_RS11840 6c941a8ed46b99ae31ab2efb949c3f5b 632 Gene3D G3DSA:2.140.10.10 2 400 5.9E-19 T 28-03-2018 MKLM6_RS11840 6c941a8ed46b99ae31ab2efb949c3f5b 632 SUPERFAMILY SSF50998 356 385 1.83E-14 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MKLM6_RS11840 6c941a8ed46b99ae31ab2efb949c3f5b 632 SUPERFAMILY SSF50998 257 310 1.83E-14 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MKLM6_RS11840 6c941a8ed46b99ae31ab2efb949c3f5b 632 SUPERFAMILY SSF50998 13 212 1.83E-14 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MKLM6_RS11840 6c941a8ed46b99ae31ab2efb949c3f5b 632 SUPERFAMILY SSF50998 444 483 1.83E-14 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MKLM6_RS04590 66eface773eb18c696b2de60789cd90d 104 Hamap MF_00529 Nitrogenase-stabilizing/protective protein NifW [nifW]. 1 103 22.976 T 28-03-2018 IPR004893 Nitrogen fixation protein NifW GO:0009399 MKLM6_RS04590 66eface773eb18c696b2de60789cd90d 104 Pfam PF03206 Nitrogen fixation protein NifW 3 99 9.2E-36 T 28-03-2018 IPR004893 Nitrogen fixation protein NifW GO:0009399 MKLM6_RS04590 66eface773eb18c696b2de60789cd90d 104 PIRSF PIRSF005790 1 104 1.5E-35 T 28-03-2018 IPR004893 Nitrogen fixation protein NifW GO:0009399 MKLM6_RS15490 8a19f99620c7ea14e05c64a9b294b084 328 PRINTS PR00410 Phenol hydroxylase reductase family signature 121 133 1.7E-13 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MKLM6_RS15490 8a19f99620c7ea14e05c64a9b294b084 328 PRINTS PR00410 Phenol hydroxylase reductase family signature 223 232 1.7E-13 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MKLM6_RS15490 8a19f99620c7ea14e05c64a9b294b084 328 PRINTS PR00410 Phenol hydroxylase reductase family signature 288 296 1.7E-13 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MKLM6_RS15490 8a19f99620c7ea14e05c64a9b294b084 328 PRINTS PR00410 Phenol hydroxylase reductase family signature 198 217 1.7E-13 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MKLM6_RS15490 8a19f99620c7ea14e05c64a9b294b084 328 PRINTS PR00410 Phenol hydroxylase reductase family signature 137 144 1.7E-13 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MKLM6_RS15490 8a19f99620c7ea14e05c64a9b294b084 328 SUPERFAMILY SSF54292 5 86 2.75E-18 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MKLM6_RS15490 8a19f99620c7ea14e05c64a9b294b084 328 Gene3D G3DSA:3.40.50.80 187 326 1.2E-21 T 28-03-2018 MKLM6_RS15490 8a19f99620c7ea14e05c64a9b294b084 328 SUPERFAMILY SSF63380 94 187 2.15E-21 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MKLM6_RS15490 8a19f99620c7ea14e05c64a9b294b084 328 SUPERFAMILY SSF52343 191 321 9.69E-32 T 28-03-2018 MKLM6_RS15490 8a19f99620c7ea14e05c64a9b294b084 328 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 137 144 7.7E-7 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MKLM6_RS15490 8a19f99620c7ea14e05c64a9b294b084 328 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 198 217 7.7E-7 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MKLM6_RS15490 8a19f99620c7ea14e05c64a9b294b084 328 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 223 232 7.7E-7 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MKLM6_RS15490 8a19f99620c7ea14e05c64a9b294b084 328 Gene3D G3DSA:3.10.20.30 1 89 5.6E-15 T 28-03-2018 IPR012675 Beta-grasp domain MKLM6_RS15490 8a19f99620c7ea14e05c64a9b294b084 328 Pfam PF00970 Oxidoreductase FAD-binding domain 96 187 1.6E-10 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 MKLM6_RS15490 8a19f99620c7ea14e05c64a9b294b084 328 Pfam PF00175 Oxidoreductase NAD-binding domain 199 301 6.2E-15 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MKLM6_RS15490 8a19f99620c7ea14e05c64a9b294b084 328 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 79 1.1E-10 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MKLM6_RS15490 8a19f99620c7ea14e05c64a9b294b084 328 Gene3D G3DSA:2.40.30.10 90 184 7.9E-19 T 28-03-2018 MKLM6_RS12535 e5b6c9227606778f494b5d76ede659fd 237 Pfam PF11141 Protein of unknown function (DUF2914) 176 233 6.9E-11 T 28-03-2018 IPR022606 Protein of unknown function DUF2914 MKLM6_RS00665 152f8a99e0cf9c57db061766df751ad5 150 SUPERFAMILY SSF53927 6 144 6.19E-34 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 MKLM6_RS00665 152f8a99e0cf9c57db061766df751ad5 150 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 98 1.3E-16 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain MKLM6_RS00665 152f8a99e0cf9c57db061766df751ad5 150 Gene3D G3DSA:3.40.140.10 2 146 1.2E-32 T 28-03-2018 MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 SUPERFAMILY SSF52540 418 621 6.46E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 Pfam PF02810 SEC-C motif 894 912 1.8E-10 T 28-03-2018 IPR004027 SEC-C motif MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 Pfam PF01043 SecA preprotein cross-linking domain 233 360 9.8E-38 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 835 20.108 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 SUPERFAMILY SSF52540 370 417 7.89E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 SUPERFAMILY SSF52540 9 228 7.89E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 Gene3D G3DSA:3.40.50.300 9 271 3.1E-57 T 28-03-2018 MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 Gene3D G3DSA:3.40.50.300 306 418 6.4E-8 T 28-03-2018 MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 SMART SM00957 6 404 0.0 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 Gene3D G3DSA:1.10.3060.10 638 738 2.5E-28 T 28-03-2018 MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 PRINTS PR00906 SecA protein signature 170 190 4.3E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 PRINTS PR00906 SecA protein signature 117 127 4.3E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 PRINTS PR00906 SecA protein signature 415 428 4.3E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 PRINTS PR00906 SecA protein signature 101 115 4.3E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 PRINTS PR00906 SecA protein signature 378 395 4.3E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 PRINTS PR00906 SecA protein signature 63 87 4.3E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 PRINTS PR00906 SecA protein signature 341 363 4.3E-71 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 821 0.0 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 SUPERFAMILY SSF81886 890 902 7.19E-82 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 SUPERFAMILY SSF81886 623 843 7.19E-82 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 ProSitePatterns PS01312 SecA family signature. 502 517 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 Pfam PF07516 SecA Wing and Scaffold domain 620 833 3.6E-67 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 SMART SM00958 228 360 1.2E-74 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 SUPERFAMILY SSF81767 230 370 2.75E-42 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 Pfam PF07517 SecA DEAD-like domain 7 403 8.7E-134 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 Gene3D G3DSA:3.10.450.50 739 914 3.0E-52 T 28-03-2018 MKLM6_RS15025 615c2939c70fa9906ac78f287b09e8dc 914 Gene3D G3DSA:3.40.50.300 419 637 6.3E-56 T 28-03-2018 MKLM6_RS07170 1547b5563164e6f2c7d242f5b4b5a48b 243 SMART SM00771 113 240 5.8E-32 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 MKLM6_RS07170 1547b5563164e6f2c7d242f5b4b5a48b 243 SUPERFAMILY SSF64383 115 240 4.32E-31 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 MKLM6_RS07170 1547b5563164e6f2c7d242f5b4b5a48b 243 Gene3D G3DSA:3.30.1400.10 115 242 3.2E-33 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 MKLM6_RS07170 1547b5563164e6f2c7d242f5b4b5a48b 243 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 116 238 2.1E-35 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 MKLM6_RS07170 1547b5563164e6f2c7d242f5b4b5a48b 243 ProDom PD035754 CELL DIVISION MEMBRANE ZIPA SEPTATION TRANSMEMBRANE HOMOLOG INNER CYCLE ZIPA 116 241 2.0E-22 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 MKLM6_RS13210 6bd25f1772c7d79a9573ec68d46a1469 307 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 259 285 - T 28-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 MKLM6_RS13210 6bd25f1772c7d79a9573ec68d46a1469 307 Pfam PF01148 Cytidylyltransferase family 4 298 7.8E-54 T 28-03-2018 MKLM6_RS19495 657baf3c470671c6aed0bbaf422f1359 423 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 421 38.819 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MKLM6_RS19495 657baf3c470671c6aed0bbaf422f1359 423 SUPERFAMILY SSF46589 1 112 3.87E-29 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 MKLM6_RS19495 657baf3c470671c6aed0bbaf422f1359 423 Gene3D G3DSA:1.10.287.40 2 104 8.8E-25 T 28-03-2018 MKLM6_RS19495 657baf3c470671c6aed0bbaf422f1359 423 SUPERFAMILY SSF55681 117 417 2.74E-98 T 28-03-2018 MKLM6_RS19495 657baf3c470671c6aed0bbaf422f1359 423 PRINTS PR00981 Seryl-tRNA synthetase signature 350 366 2.2E-30 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MKLM6_RS19495 657baf3c470671c6aed0bbaf422f1359 423 PRINTS PR00981 Seryl-tRNA synthetase signature 263 275 2.2E-30 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MKLM6_RS19495 657baf3c470671c6aed0bbaf422f1359 423 PRINTS PR00981 Seryl-tRNA synthetase signature 315 328 2.2E-30 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MKLM6_RS19495 657baf3c470671c6aed0bbaf422f1359 423 PRINTS PR00981 Seryl-tRNA synthetase signature 275 288 2.2E-30 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MKLM6_RS19495 657baf3c470671c6aed0bbaf422f1359 423 PRINTS PR00981 Seryl-tRNA synthetase signature 332 348 2.2E-30 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MKLM6_RS19495 657baf3c470671c6aed0bbaf422f1359 423 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 220 399 4.2E-32 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS19495 657baf3c470671c6aed0bbaf422f1359 423 Gene3D G3DSA:3.30.930.10 105 423 8.7E-91 T 28-03-2018 MKLM6_RS19495 657baf3c470671c6aed0bbaf422f1359 423 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 106 3.8E-28 T 28-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 MKLM6_RS19495 657baf3c470671c6aed0bbaf422f1359 423 PIRSF PIRSF001529 1 423 8.7E-171 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MKLM6_RS19495 657baf3c470671c6aed0bbaf422f1359 423 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 416 1.2E-159 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MKLM6_RS13945 a63672924f4bc9c2bcd005ea5b64759c 235 SUPERFAMILY SSF53335 13 229 1.15E-42 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS13945 a63672924f4bc9c2bcd005ea5b64759c 235 Gene3D G3DSA:3.40.50.150 2 234 5.0E-45 T 28-03-2018 MKLM6_RS13945 a63672924f4bc9c2bcd005ea5b64759c 235 Pfam PF13489 Methyltransferase domain 42 202 5.2E-24 T 28-03-2018 MKLM6_RS13945 a63672924f4bc9c2bcd005ea5b64759c 235 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 9 234 37.337 T 28-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 MKLM6_RS13945 a63672924f4bc9c2bcd005ea5b64759c 235 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 11 228 1.8E-79 T 28-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 MKLM6_RS04005 4db80903462f6ac4cc255a70d6cde669 211 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 45 206 36.46 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MKLM6_RS04005 4db80903462f6ac4cc255a70d6cde669 211 SUPERFAMILY SSF55068 4 209 1.02E-77 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MKLM6_RS04005 4db80903462f6ac4cc255a70d6cde669 211 Gene3D G3DSA:3.30.1060.10 28 204 5.1E-75 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MKLM6_RS04005 4db80903462f6ac4cc255a70d6cde669 211 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 47 200 5.1E-63 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MKLM6_RS04005 4db80903462f6ac4cc255a70d6cde669 211 Pfam PF01625 Peptide methionine sulfoxide reductase 47 200 2.0E-62 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MKLM6_RS22300 9d7f87b753175b7f66bac8e9c7c9d23d 1161 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 463 469 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MKLM6_RS22300 9d7f87b753175b7f66bac8e9c7c9d23d 1161 Gene3D G3DSA:1.20.5.340 834 1123 0.0058 T 28-03-2018 MKLM6_RS22300 9d7f87b753175b7f66bac8e9c7c9d23d 1161 Gene3D G3DSA:3.40.50.150 234 597 6.4E-32 T 28-03-2018 MKLM6_RS22300 9d7f87b753175b7f66bac8e9c7c9d23d 1161 SUPERFAMILY SSF53335 455 588 1.1E-58 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS22300 9d7f87b753175b7f66bac8e9c7c9d23d 1161 SUPERFAMILY SSF53335 45 83 1.1E-58 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS22300 9d7f87b753175b7f66bac8e9c7c9d23d 1161 SUPERFAMILY SSF53335 286 350 1.1E-58 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS22300 9d7f87b753175b7f66bac8e9c7c9d23d 1161 SUPERFAMILY SSF53335 111 251 1.1E-58 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS22300 9d7f87b753175b7f66bac8e9c7c9d23d 1161 Pfam PF07669 Eco57I restriction-modification methylase 459 551 1.5E-8 T 28-03-2018 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 MKLM6_RS22300 9d7f87b753175b7f66bac8e9c7c9d23d 1161 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 460 472 2.4E-9 T 28-03-2018 MKLM6_RS22300 9d7f87b753175b7f66bac8e9c7c9d23d 1161 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 290 304 2.4E-9 T 28-03-2018 MKLM6_RS22300 9d7f87b753175b7f66bac8e9c7c9d23d 1161 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 493 517 2.4E-9 T 28-03-2018 MKLM6_RS22300 9d7f87b753175b7f66bac8e9c7c9d23d 1161 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 232 248 2.4E-9 T 28-03-2018 MKLM6_RS22300 9d7f87b753175b7f66bac8e9c7c9d23d 1161 Gene3D G3DSA:3.90.220.10 622 794 2.7E-17 T 28-03-2018 MKLM6_RS04335 f89a9ef767bd5f14ce4aecaf7b5d1fe8 240 Pfam PF00589 Phage integrase family 51 222 7.0E-30 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS04335 f89a9ef767bd5f14ce4aecaf7b5d1fe8 240 Gene3D G3DSA:1.10.443.10 52 239 1.2E-40 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS04335 f89a9ef767bd5f14ce4aecaf7b5d1fe8 240 Gene3D G3DSA:1.10.150.130 1 51 1.9E-8 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal MKLM6_RS04335 f89a9ef767bd5f14ce4aecaf7b5d1fe8 240 SUPERFAMILY SSF56349 3 232 2.88E-48 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS16065 31042c514df0f1bec65ee091d19c7ab7 1210 Gene3D G3DSA:3.30.70.20 678 801 1.8E-25 T 28-03-2018 MKLM6_RS16065 31042c514df0f1bec65ee091d19c7ab7 1210 PIRSF PIRSF000159 1 1192 0.0 T 28-03-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 MKLM6_RS16065 31042c514df0f1bec65ee091d19c7ab7 1210 SMART SM00890 631 688 2.9E-27 T 28-03-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 MKLM6_RS16065 31042c514df0f1bec65ee091d19c7ab7 1210 Pfam PF13484 4Fe-4S double cluster binding domain 698 767 8.7E-10 T 28-03-2018 MKLM6_RS16065 31042c514df0f1bec65ee091d19c7ab7 1210 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 433 616 1.5E-26 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 MKLM6_RS16065 31042c514df0f1bec65ee091d19c7ab7 1210 Gene3D G3DSA:4.10.780.10 643 677 1.9E-15 T 28-03-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 MKLM6_RS16065 31042c514df0f1bec65ee091d19c7ab7 1210 Pfam PF10371 Domain of unknown function 641 687 6.9E-21 T 28-03-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 MKLM6_RS16065 31042c514df0f1bec65ee091d19c7ab7 1210 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 971 1083 7.1E-10 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MKLM6_RS16065 31042c514df0f1bec65ee091d19c7ab7 1210 Gene3D G3DSA:3.40.50.920 259 422 8.3E-48 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MKLM6_RS16065 31042c514df0f1bec65ee091d19c7ab7 1210 SUPERFAMILY SSF52518 4 258 1.53E-75 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS16065 31042c514df0f1bec65ee091d19c7ab7 1210 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 18 247 5.0E-79 T 28-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 MKLM6_RS16065 31042c514df0f1bec65ee091d19c7ab7 1210 SUPERFAMILY SSF52922 260 419 3.34E-43 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MKLM6_RS16065 31042c514df0f1bec65ee091d19c7ab7 1210 SUPERFAMILY SSF53323 424 677 3.66E-75 T 28-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 MKLM6_RS16065 31042c514df0f1bec65ee091d19c7ab7 1210 Gene3D G3DSA:3.40.920.10 423 635 5.9E-55 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 MKLM6_RS16065 31042c514df0f1bec65ee091d19c7ab7 1210 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 269 354 6.6E-15 T 28-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II MKLM6_RS16065 31042c514df0f1bec65ee091d19c7ab7 1210 SUPERFAMILY SSF54862 674 849 2.83E-20 T 28-03-2018 MKLM6_RS16065 31042c514df0f1bec65ee091d19c7ab7 1210 SUPERFAMILY SSF52518 804 1189 3.6E-127 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS16065 31042c514df0f1bec65ee091d19c7ab7 1210 TIGRFAM TIGR02176 pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase 6 1182 0.0 T 28-03-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 MKLM6_RS16065 31042c514df0f1bec65ee091d19c7ab7 1210 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 755 766 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MKLM6_RS16065 31042c514df0f1bec65ee091d19c7ab7 1210 Gene3D G3DSA:3.40.50.970 803 1185 2.3E-108 T 28-03-2018 MKLM6_RS16065 31042c514df0f1bec65ee091d19c7ab7 1210 Gene3D G3DSA:3.40.50.970 2 258 3.5E-50 T 28-03-2018 MKLM6_RS21320 3b2230b2ea5020566bca8d5e3b6d386b 810 Gene3D G3DSA:2.40.170.20 270 810 7.7E-81 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS21320 3b2230b2ea5020566bca8d5e3b6d386b 810 Pfam PF00593 TonB dependent receptor 331 794 3.5E-60 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS21320 3b2230b2ea5020566bca8d5e3b6d386b 810 SUPERFAMILY SSF56935 118 809 1.0E-126 T 28-03-2018 MKLM6_RS21320 3b2230b2ea5020566bca8d5e3b6d386b 810 Gene3D G3DSA:2.170.130.10 115 268 7.1E-23 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS21320 3b2230b2ea5020566bca8d5e3b6d386b 810 Pfam PF07715 TonB-dependent Receptor Plug Domain 160 255 2.9E-16 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS21320 3b2230b2ea5020566bca8d5e3b6d386b 810 Pfam PF07660 Secretin and TonB N terminus short domain 62 111 5.1E-9 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MKLM6_RS21320 3b2230b2ea5020566bca8d5e3b6d386b 810 SMART SM00965 61 112 4.3E-14 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MKLM6_RS21320 3b2230b2ea5020566bca8d5e3b6d386b 810 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 161 799 1.9E-106 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 MKLM6_RS15350 d5adeb18d1828fab1f719c3940c17204 629 Gene3D G3DSA:3.40.50.620 224 629 2.0E-74 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS15350 d5adeb18d1828fab1f719c3940c17204 629 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 560 2.6E-151 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MKLM6_RS15350 d5adeb18d1828fab1f719c3940c17204 629 TIGRFAM TIGR03108 eps_aminotran_1: exosortase A system-associated amidotransferase 1 1 626 0.0 T 28-03-2018 IPR017539 Exosortase 1 system-associated amidotransferase 1 MKLM6_RS15350 d5adeb18d1828fab1f719c3940c17204 629 Pfam PF13537 Glutamine amidotransferase domain 48 167 4.1E-50 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain MKLM6_RS15350 d5adeb18d1828fab1f719c3940c17204 629 Gene3D G3DSA:3.60.20.10 1 223 1.5E-58 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MKLM6_RS15350 d5adeb18d1828fab1f719c3940c17204 629 PIRSF PIRSF001589 1 629 2.1E-171 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MKLM6_RS15350 d5adeb18d1828fab1f719c3940c17204 629 SUPERFAMILY SSF56235 1 226 5.75E-65 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MKLM6_RS15350 d5adeb18d1828fab1f719c3940c17204 629 SUPERFAMILY SSF52402 480 620 1.34E-84 T 28-03-2018 MKLM6_RS15350 d5adeb18d1828fab1f719c3940c17204 629 SUPERFAMILY SSF52402 234 382 1.34E-84 T 28-03-2018 MKLM6_RS15350 d5adeb18d1828fab1f719c3940c17204 629 Pfam PF00733 Asparagine synthase 244 624 2.4E-99 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 MKLM6_RS01575 2a7c01dea01039040113f1ca975e7831 130 Pfam PF04134 Protein of unknown function, DUF393 9 114 8.1E-21 T 28-03-2018 IPR007263 Protein of unknown function DUF393 MKLM6_RS13310 9d7d141fec3a0877833712c842f0c9c9 447 Pfam PF05896 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) 3 255 1.5E-104 T 28-03-2018 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 MKLM6_RS13310 9d7d141fec3a0877833712c842f0c9c9 447 Pfam PF11973 NQRA C-terminal domain 260 308 3.9E-21 T 28-03-2018 IPR022615 Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain GO:0016655|GO:0055114 MKLM6_RS13310 9d7d141fec3a0877833712c842f0c9c9 447 Gene3D G3DSA:2.40.50.100 42 94 5.9E-4 T 28-03-2018 MKLM6_RS13310 9d7d141fec3a0877833712c842f0c9c9 447 Hamap MF_00425 Na(+)-translocating NADH-quinone reductase subunit A [nqrA]. 2 447 43.796 T 28-03-2018 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 MKLM6_RS13310 9d7d141fec3a0877833712c842f0c9c9 447 TIGRFAM TIGR01936 nqrA: NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit 4 447 1.4E-169 T 28-03-2018 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 MKLM6_RS12300 2153e0107f8cae5aef67847805f10fb6 459 PIRSF PIRSF006060 4 458 5.1E-78 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MKLM6_RS12300 2153e0107f8cae5aef67847805f10fb6 459 Pfam PF13520 Amino acid permease 21 433 1.4E-53 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MKLM6_RS11750 c4915b8521a919b21ff086715d2d6aa9 409 SUPERFAMILY SSF88659 306 396 2.62E-20 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11750 c4915b8521a919b21ff086715d2d6aa9 409 SUPERFAMILY SSF88659 245 310 2.96E-7 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11750 c4915b8521a919b21ff086715d2d6aa9 409 Pfam PF04542 Sigma-70 region 2 173 240 7.5E-16 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11750 c4915b8521a919b21ff086715d2d6aa9 409 SUPERFAMILY SSF88946 140 241 2.04E-29 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11750 c4915b8521a919b21ff086715d2d6aa9 409 Pfam PF04545 Sigma-70, region 4 342 394 9.7E-16 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11750 c4915b8521a919b21ff086715d2d6aa9 409 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 169 395 5.2E-30 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11750 c4915b8521a919b21ff086715d2d6aa9 409 PRINTS PR00046 Major sigma-70 factor signature 196 209 9.2E-21 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11750 c4915b8521a919b21ff086715d2d6aa9 409 PRINTS PR00046 Major sigma-70 factor signature 220 228 9.2E-21 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11750 c4915b8521a919b21ff086715d2d6aa9 409 PRINTS PR00046 Major sigma-70 factor signature 345 357 9.2E-21 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11750 c4915b8521a919b21ff086715d2d6aa9 409 PRINTS PR00046 Major sigma-70 factor signature 366 381 9.2E-21 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11750 c4915b8521a919b21ff086715d2d6aa9 409 PRINTS PR00046 Major sigma-70 factor signature 381 392 9.2E-21 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11750 c4915b8521a919b21ff086715d2d6aa9 409 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 196 209 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11750 c4915b8521a919b21ff086715d2d6aa9 409 Gene3D G3DSA:1.10.10.10 241 292 6.1E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS11750 c4915b8521a919b21ff086715d2d6aa9 409 Gene3D G3DSA:1.10.601.10 10 240 4.0E-31 T 28-03-2018 MKLM6_RS11750 c4915b8521a919b21ff086715d2d6aa9 409 Gene3D G3DSA:1.10.10.10 335 404 1.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS05010 9c9ada8bea576ea645f6a8d6cb4a999d 337 Pfam PF00579 tRNA synthetases class I (W and Y) 3 284 6.5E-56 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS05010 9c9ada8bea576ea645f6a8d6cb4a999d 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 9.9E-19 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MKLM6_RS05010 9c9ada8bea576ea645f6a8d6cb4a999d 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 152 173 9.9E-19 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MKLM6_RS05010 9c9ada8bea576ea645f6a8d6cb4a999d 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 68 87 9.9E-19 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MKLM6_RS05010 9c9ada8bea576ea645f6a8d6cb4a999d 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 203 213 9.9E-19 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MKLM6_RS05010 9c9ada8bea576ea645f6a8d6cb4a999d 337 Gene3D G3DSA:1.10.240.10 213 300 4.4E-27 T 28-03-2018 MKLM6_RS05010 9c9ada8bea576ea645f6a8d6cb4a999d 337 Gene3D G3DSA:3.40.50.620 1 212 7.3E-64 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS05010 9c9ada8bea576ea645f6a8d6cb4a999d 337 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 332 1.3E-91 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MKLM6_RS05010 9c9ada8bea576ea645f6a8d6cb4a999d 337 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 3 333 36.614 T 28-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 MKLM6_RS05010 9c9ada8bea576ea645f6a8d6cb4a999d 337 SUPERFAMILY SSF52374 5 332 4.79E-86 T 28-03-2018 MKLM6_RS12165 bbc09833c3e529b93859d8ea951c3e65 68 SUPERFAMILY SSF50118 4 67 7.19E-5 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor MKLM6_RS12165 bbc09833c3e529b93859d8ea951c3e65 68 Gene3D G3DSA:2.30.30.110 14 68 0.031 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor MKLM6_RS14640 7a5b74aa3ec4b5e6c093191a3416db9b 360 PIRSF PIRSF004869 3 320 5.2E-92 T 28-03-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted MKLM6_RS14640 7a5b74aa3ec4b5e6c093191a3416db9b 360 SUPERFAMILY SSF102114 47 322 9.22E-41 T 28-03-2018 MKLM6_RS14640 7a5b74aa3ec4b5e6c093191a3416db9b 360 Gene3D G3DSA:3.20.20.70 63 320 1.5E-23 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS14640 7a5b74aa3ec4b5e6c093191a3416db9b 360 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 12 359 1.3E-197 T 28-03-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme MKLM6_RS14640 7a5b74aa3ec4b5e6c093191a3416db9b 360 Pfam PF04055 Radical SAM superfamily 87 236 1.2E-15 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS12775 1b87e0b442fee64c92f8e3387b5384df 753 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 229 406 2.4E-26 T 28-03-2018 IPR004477 ComEC/Rec2-related protein MKLM6_RS12775 1b87e0b442fee64c92f8e3387b5384df 753 Pfam PF03772 Competence protein 208 475 6.7E-65 T 28-03-2018 IPR004477 ComEC/Rec2-related protein MKLM6_RS12775 1b87e0b442fee64c92f8e3387b5384df 753 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 70 728 3.0E-122 T 28-03-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 MKLM6_RS12775 1b87e0b442fee64c92f8e3387b5384df 753 Gene3D G3DSA:3.60.15.10 502 737 2.2E-27 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS12775 1b87e0b442fee64c92f8e3387b5384df 753 Pfam PF00753 Metallo-beta-lactamase superfamily 510 690 7.5E-11 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS12775 1b87e0b442fee64c92f8e3387b5384df 753 SUPERFAMILY SSF56281 499 737 2.17E-45 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS12775 1b87e0b442fee64c92f8e3387b5384df 753 Pfam PF13567 Domain of unknown function (DUF4131) 32 164 1.3E-25 T 28-03-2018 IPR025405 Domain of unknown function DUF4131 MKLM6_RS12775 1b87e0b442fee64c92f8e3387b5384df 753 SMART SM00849 512 699 4.2E-8 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS08885 a569758d93825b6913241bc1b8658dc6 474 Gene3D G3DSA:1.20.5.1040 5 57 9.8E-6 T 28-03-2018 MKLM6_RS08885 a569758d93825b6913241bc1b8658dc6 474 SMART SM00387 349 457 2.4E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS08885 a569758d93825b6913241bc1b8658dc6 474 Gene3D G3DSA:1.10.287.130 228 286 1.7E-12 T 28-03-2018 MKLM6_RS08885 a569758d93825b6913241bc1b8658dc6 474 SUPERFAMILY SSF47384 221 301 2.16E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS08885 a569758d93825b6913241bc1b8658dc6 474 Pfam PF00512 His Kinase A (phospho-acceptor) domain 239 301 1.9E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS08885 a569758d93825b6913241bc1b8658dc6 474 Gene3D G3DSA:3.30.565.10 287 456 3.0E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS08885 a569758d93825b6913241bc1b8658dc6 474 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 455 1.2E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS08885 a569758d93825b6913241bc1b8658dc6 474 SMART SM00388 238 303 9.4E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS08885 a569758d93825b6913241bc1b8658dc6 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 2.0E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS08885 a569758d93825b6913241bc1b8658dc6 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 454 2.0E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS08885 a569758d93825b6913241bc1b8658dc6 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 2.0E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS08885 a569758d93825b6913241bc1b8658dc6 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 2.0E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS08885 a569758d93825b6913241bc1b8658dc6 474 SUPERFAMILY SSF55874 293 455 6.29E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS08885 a569758d93825b6913241bc1b8658dc6 474 Pfam PF08521 Two-component sensor kinase N-terminal 19 160 2.1E-34 T 28-03-2018 IPR013727 Two-component sensor kinase, N-terminal MKLM6_RS17835 b7729c6f0de1f864276590d0aba89722 938 SUPERFAMILY SSF54001 773 864 9.81E-6 T 28-03-2018 MKLM6_RS17835 b7729c6f0de1f864276590d0aba89722 938 Gene3D G3DSA:3.40.50.1460 66 336 7.5E-48 T 28-03-2018 MKLM6_RS17835 b7729c6f0de1f864276590d0aba89722 938 Pfam PF00656 Caspase domain 68 311 2.0E-21 T 28-03-2018 MKLM6_RS17835 b7729c6f0de1f864276590d0aba89722 938 Gene3D G3DSA:3.90.1720.10 742 902 6.9E-10 T 28-03-2018 MKLM6_RS17835 b7729c6f0de1f864276590d0aba89722 938 SUPERFAMILY SSF52129 59 297 2.79E-9 T 28-03-2018 IPR029030 Caspase-like domain MKLM6_RS15215 6605c018560ee30608dfcc1cd2c523bd 291 Gene3D G3DSA:3.40.50.150 10 245 6.4E-33 T 28-03-2018 MKLM6_RS15215 6605c018560ee30608dfcc1cd2c523bd 291 Pfam PF13649 Methyltransferase domain 70 169 1.3E-22 T 28-03-2018 MKLM6_RS15215 6605c018560ee30608dfcc1cd2c523bd 291 SUPERFAMILY SSF53335 44 262 1.47E-36 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS03935 8c8a55e6a9881c7f9f23d35e2117227a 451 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 4 439 1.5E-185 T 28-03-2018 MKLM6_RS03935 8c8a55e6a9881c7f9f23d35e2117227a 451 Gene3D G3DSA:3.20.20.70 12 410 3.6E-52 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS03935 8c8a55e6a9881c7f9f23d35e2117227a 451 SMART SM00729 147 367 7.0E-60 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MKLM6_RS03935 8c8a55e6a9881c7f9f23d35e2117227a 451 Pfam PF00919 Uncharacterized protein family UPF0004 4 104 6.0E-28 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 MKLM6_RS03935 8c8a55e6a9881c7f9f23d35e2117227a 451 Pfam PF04055 Radical SAM superfamily 151 325 8.5E-29 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS03935 8c8a55e6a9881c7f9f23d35e2117227a 451 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 151 171 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 MKLM6_RS03935 8c8a55e6a9881c7f9f23d35e2117227a 451 Pfam PF01938 TRAM domain 380 439 9.1E-18 T 28-03-2018 IPR002792 TRAM domain MKLM6_RS03935 8c8a55e6a9881c7f9f23d35e2117227a 451 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 437 3.8E-149 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 MKLM6_RS03935 8c8a55e6a9881c7f9f23d35e2117227a 451 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 3 440 72.623 T 28-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 MKLM6_RS03935 8c8a55e6a9881c7f9f23d35e2117227a 451 SUPERFAMILY SSF102114 129 371 2.49E-62 T 28-03-2018 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 Pfam PF01627 Hpt domain 831 910 3.4E-5 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 Pfam PF00672 HAMP domain 188 238 7.1E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 SMART SM00388 274 339 6.0E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 SUPERFAMILY SSF158472 188 238 8.37E-7 T 28-03-2018 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 480 2.1E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 455 2.1E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 PRINTS PR00344 Bacterial sensor protein C-terminal signature 486 499 2.1E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 441 2.1E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 SUPERFAMILY SSF52172 667 794 3.56E-38 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 Gene3D G3DSA:1.20.120.160 821 967 1.4E-10 T 28-03-2018 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 SUPERFAMILY SSF47226 765 778 4.45E-13 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 SUPERFAMILY SSF47226 811 908 4.45E-13 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 SUPERFAMILY SSF47384 260 340 5.3E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 Gene3D G3DSA:3.40.50.2300 667 800 4.2E-41 T 28-03-2018 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 SUPERFAMILY SSF55874 328 498 5.63E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 Pfam PF00072 Response regulator receiver domain 671 782 2.4E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 Pfam PF00072 Response regulator receiver domain 520 640 5.7E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 Gene3D G3DSA:3.30.450.20 38 156 1.5E-4 T 28-03-2018 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 Pfam PF17152 Periplasmic sensor domain 46 149 6.2E-18 T 28-03-2018 IPR033417 Periplasmic sensor domain CHASE8 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 386 500 2.0E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 Gene3D G3DSA:3.40.50.2300 513 666 5.8E-31 T 28-03-2018 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 SMART SM00387 386 504 1.1E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 Gene3D G3DSA:1.10.287.130 264 335 1.0E-18 T 28-03-2018 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 SMART SM00304 188 241 7.0E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 Gene3D G3DSA:3.30.565.10 344 512 4.3E-48 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 SMART SM00448 518 640 9.3E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 SMART SM00448 669 782 2.4E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 Pfam PF00512 His Kinase A (phospho-acceptor) domain 274 339 1.2E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS19615 9974a51e943a9241ba66875c5f798059 1002 SUPERFAMILY SSF52172 517 645 1.42E-29 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS12785 b878da3075c9ece36bce2b09e69632f7 643 Pfam PF06480 FtsH Extracellular 54 141 1.6E-9 T 28-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 MKLM6_RS12785 b878da3075c9ece36bce2b09e69632f7 643 SUPERFAMILY SSF52540 192 440 5.89E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS12785 b878da3075c9ece36bce2b09e69632f7 643 SMART SM00382 231 371 2.3E-22 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS12785 b878da3075c9ece36bce2b09e69632f7 643 Pfam PF01434 Peptidase family M41 430 638 6.2E-74 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 MKLM6_RS12785 b878da3075c9ece36bce2b09e69632f7 643 SUPERFAMILY SSF140990 450 641 8.76E-66 T 28-03-2018 MKLM6_RS12785 b878da3075c9ece36bce2b09e69632f7 643 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 235 367 3.0E-42 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MKLM6_RS12785 b878da3075c9ece36bce2b09e69632f7 643 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 9 642 35.158 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 MKLM6_RS12785 b878da3075c9ece36bce2b09e69632f7 643 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 149 640 8.7E-208 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 MKLM6_RS12785 b878da3075c9ece36bce2b09e69632f7 643 ProSitePatterns PS00674 AAA-protein family signature. 339 357 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 MKLM6_RS12785 b878da3075c9ece36bce2b09e69632f7 643 Gene3D G3DSA:1.10.8.60 384 455 5.7E-23 T 28-03-2018 MKLM6_RS12785 b878da3075c9ece36bce2b09e69632f7 643 Gene3D G3DSA:3.40.50.300 181 383 1.9E-59 T 28-03-2018 MKLM6_RS20925 28e06d2ac1ba701d33b69008cdd1aeed 320 Pfam PF05598 Transposase domain (DUF772) 54 126 3.1E-18 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS20925 28e06d2ac1ba701d33b69008cdd1aeed 320 Pfam PF01609 Transposase DDE domain 142 310 1.5E-29 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS03590 28e06d2ac1ba701d33b69008cdd1aeed 320 Pfam PF05598 Transposase domain (DUF772) 54 126 3.1E-18 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS03590 28e06d2ac1ba701d33b69008cdd1aeed 320 Pfam PF01609 Transposase DDE domain 142 310 1.5E-29 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS19005 8fa8d1fa6357dcd25141e61b87903f8e 426 SMART SM00448 12 125 1.4E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS19005 8fa8d1fa6357dcd25141e61b87903f8e 426 SUPERFAMILY SSF55874 264 422 3.27E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS19005 8fa8d1fa6357dcd25141e61b87903f8e 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 419 4.5E-21 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS19005 8fa8d1fa6357dcd25141e61b87903f8e 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 365 4.5E-21 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS19005 8fa8d1fa6357dcd25141e61b87903f8e 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 379 4.5E-21 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS19005 8fa8d1fa6357dcd25141e61b87903f8e 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 400 4.5E-21 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS19005 8fa8d1fa6357dcd25141e61b87903f8e 426 Gene3D G3DSA:3.30.565.10 272 422 3.5E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS19005 8fa8d1fa6357dcd25141e61b87903f8e 426 Pfam PF00512 His Kinase A (phospho-acceptor) domain 173 273 2.3E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS19005 8fa8d1fa6357dcd25141e61b87903f8e 426 SUPERFAMILY SSF52172 11 157 3.7E-38 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS19005 8fa8d1fa6357dcd25141e61b87903f8e 426 SUPERFAMILY SSF47384 158 206 3.73E-5 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS19005 8fa8d1fa6357dcd25141e61b87903f8e 426 Gene3D G3DSA:3.40.50.2300 9 160 1.7E-35 T 28-03-2018 MKLM6_RS19005 8fa8d1fa6357dcd25141e61b87903f8e 426 Pfam PF00072 Response regulator receiver domain 14 125 7.7E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS19005 8fa8d1fa6357dcd25141e61b87903f8e 426 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 317 420 4.2E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS19005 8fa8d1fa6357dcd25141e61b87903f8e 426 SMART SM00387 314 422 1.4E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS19005 8fa8d1fa6357dcd25141e61b87903f8e 426 Gene3D G3DSA:1.10.287.130 161 270 2.3E-10 T 28-03-2018 MKLM6_RS10700 22db12a7ab18d8a1be8a5ff986492931 394 SUPERFAMILY SSF53383 3 390 1.88E-110 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS10700 22db12a7ab18d8a1be8a5ff986492931 394 Gene3D G3DSA:3.40.640.10 42 277 1.2E-52 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS10700 22db12a7ab18d8a1be8a5ff986492931 394 Gene3D G3DSA:3.90.1150.10 278 392 1.5E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS10700 22db12a7ab18d8a1be8a5ff986492931 394 Pfam PF00155 Aminotransferase class I and II 31 375 7.0E-56 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MKLM6_RS22600 326444b0eb33641cce806934785e7c3d 168 TIGRFAM TIGR04300 exosort_XrtM: exosortase family protein XrtM 16 166 2.0E-61 T 28-03-2018 IPR027567 Exosortase XrtM MKLM6_RS22600 326444b0eb33641cce806934785e7c3d 168 Pfam PF09721 Transmembrane exosortase (Exosortase_EpsH) 46 155 5.3E-7 T 28-03-2018 IPR019127 Exosortase EpsH-related MKLM6_RS22600 326444b0eb33641cce806934785e7c3d 168 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 71 156 7.5E-15 T 28-03-2018 IPR026392 Exosortase/Archaeosortase domain MKLM6_RS00480 e97175a75fe0d71667d99d1507e69a87 232 Pfam PF08808 RES domain 66 215 9.5E-31 T 28-03-2018 IPR014914 RES domain MKLM6_RS00480 e97175a75fe0d71667d99d1507e69a87 232 SMART SM00953 78 207 7.4E-31 T 28-03-2018 IPR014914 RES domain MKLM6_RS20745 380714497062a1c566d6c17fd7532a70 785 Gene3D G3DSA:3.90.1170.50 216 365 1.0E-30 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MKLM6_RS20745 380714497062a1c566d6c17fd7532a70 785 Gene3D G3DSA:3.30.365.10 61 215 5.5E-36 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MKLM6_RS20745 380714497062a1c566d6c17fd7532a70 785 PIRSF PIRSF036389 17 785 8.0E-257 T 28-03-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related MKLM6_RS20745 380714497062a1c566d6c17fd7532a70 785 SUPERFAMILY SSF56003 74 272 4.53E-40 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MKLM6_RS20745 380714497062a1c566d6c17fd7532a70 785 Gene3D G3DSA:3.30.365.10 643 783 1.1E-35 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MKLM6_RS20745 380714497062a1c566d6c17fd7532a70 785 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 79 211 4.7E-13 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MKLM6_RS20745 380714497062a1c566d6c17fd7532a70 785 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 347 633 2.4E-35 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MKLM6_RS20745 380714497062a1c566d6c17fd7532a70 785 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 645 729 1.6E-15 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MKLM6_RS20745 380714497062a1c566d6c17fd7532a70 785 SUPERFAMILY SSF56003 350 782 2.91E-117 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MKLM6_RS20745 380714497062a1c566d6c17fd7532a70 785 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 26 52 3.3E-4 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal MKLM6_RS20745 380714497062a1c566d6c17fd7532a70 785 Gene3D G3DSA:3.30.365.10 366 460 8.9E-32 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MKLM6_RS20745 380714497062a1c566d6c17fd7532a70 785 Gene3D G3DSA:3.30.365.10 461 642 4.5E-31 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MKLM6_RS20745 380714497062a1c566d6c17fd7532a70 785 SMART SM01008 239 328 4.4E-25 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MKLM6_RS18555 4519fb3e98d3c711a3e064bd7111c90a 283 SUPERFAMILY SSF54211 6 157 1.29E-45 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS18555 4519fb3e98d3c711a3e064bd7111c90a 283 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 5 266 31.638 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MKLM6_RS18555 4519fb3e98d3c711a3e064bd7111c90a 283 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 6 278 7.2E-75 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MKLM6_RS18555 4519fb3e98d3c711a3e064bd7111c90a 283 Pfam PF00288 GHMP kinases N terminal domain 88 144 7.6E-12 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 MKLM6_RS18555 4519fb3e98d3c711a3e064bd7111c90a 283 Pfam PF08544 GHMP kinases C terminal 208 253 2.7E-9 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain MKLM6_RS18555 4519fb3e98d3c711a3e064bd7111c90a 283 SUPERFAMILY SSF55060 161 277 6.71E-29 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain MKLM6_RS18555 4519fb3e98d3c711a3e064bd7111c90a 283 Gene3D G3DSA:3.30.70.890 162 279 2.3E-23 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain MKLM6_RS18555 4519fb3e98d3c711a3e064bd7111c90a 283 PIRSF PIRSF010376 5 278 1.0E-79 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MKLM6_RS18555 4519fb3e98d3c711a3e064bd7111c90a 283 Gene3D G3DSA:3.30.230.10 5 160 1.4E-44 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MKLM6_RS16240 3de1d49a230b05e6b016c88cc53942da 266 TIGRFAM TIGR03870 ABC_MoxJ: methanol oxidation system protein MoxJ 13 256 2.3E-105 T 28-03-2018 IPR022455 Methanol oxidation system protein MoxJ GO:0042597|GO:0046170 MKLM6_RS16240 3de1d49a230b05e6b016c88cc53942da 266 Gene3D G3DSA:3.40.190.10 8 128 8.8E-11 T 28-03-2018 MKLM6_RS16240 3de1d49a230b05e6b016c88cc53942da 266 Gene3D G3DSA:3.40.190.10 129 251 1.8E-7 T 28-03-2018 MKLM6_RS16240 3de1d49a230b05e6b016c88cc53942da 266 SMART SM00062 12 251 1.3E-32 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MKLM6_RS16240 3de1d49a230b05e6b016c88cc53942da 266 SUPERFAMILY SSF53850 6 243 6.46E-25 T 28-03-2018 MKLM6_RS16240 3de1d49a230b05e6b016c88cc53942da 266 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 13 243 1.3E-18 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MKLM6_RS09030 19b17ff6e77badf826b972e2476c24aa 440 Gene3D G3DSA:2.40.128.130 106 438 2.1E-35 T 28-03-2018 MKLM6_RS09030 19b17ff6e77badf826b972e2476c24aa 440 Pfam PF03797 Autotransporter beta-domain 160 418 1.2E-36 T 28-03-2018 IPR005546 Autotransporter beta-domain MKLM6_RS09030 19b17ff6e77badf826b972e2476c24aa 440 SMART SM00869 156 429 1.9E-16 T 28-03-2018 IPR005546 Autotransporter beta-domain MKLM6_RS09030 19b17ff6e77badf826b972e2476c24aa 440 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 111 437 1.4E-13 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 MKLM6_RS09030 19b17ff6e77badf826b972e2476c24aa 440 SUPERFAMILY SSF103515 115 437 8.63E-32 T 28-03-2018 IPR005546 Autotransporter beta-domain MKLM6_RS05680 105a68517cd6f67a98a0805e08d65980 326 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 225 312 1.4E-10 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MKLM6_RS05680 105a68517cd6f67a98a0805e08d65980 326 Gene3D G3DSA:3.30.1220.10 209 315 3.4E-11 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MKLM6_RS05680 105a68517cd6f67a98a0805e08d65980 326 SUPERFAMILY SSF52540 10 188 9.0E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS05680 105a68517cd6f67a98a0805e08d65980 326 SMART SM00833 225 317 5.4E-7 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MKLM6_RS05680 105a68517cd6f67a98a0805e08d65980 326 SUPERFAMILY SSF90002 225 305 3.53E-10 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MKLM6_RS05680 105a68517cd6f67a98a0805e08d65980 326 Gene3D G3DSA:3.40.50.300 9 200 1.2E-28 T 28-03-2018 MKLM6_RS05680 105a68517cd6f67a98a0805e08d65980 326 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 13 188 3.0E-34 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain MKLM6_RS17530 c9010f54e32befc8209c437690b86c1f 165 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 3 133 6.3E-22 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily MKLM6_RS17530 c9010f54e32befc8209c437690b86c1f 165 Gene3D G3DSA:3.40.50.2300 1 135 7.0E-33 T 28-03-2018 MKLM6_RS17530 c9010f54e32befc8209c437690b86c1f 165 SMART SM00226 1 135 1.0E-39 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily MKLM6_RS17530 c9010f54e32befc8209c437690b86c1f 165 SUPERFAMILY SSF52788 1 135 3.14E-38 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily MKLM6_RS08180 925ac4f42c8f08b4c63ab5c184c3a7a4 772 Pfam PF07587 Protein of unknown function (DUF1553) 463 717 2.3E-92 T 28-03-2018 IPR022655 Domain of unknown function DUF1553 MKLM6_RS08180 925ac4f42c8f08b4c63ab5c184c3a7a4 772 Pfam PF07583 Protein of unknown function (DUF1549) 66 272 4.7E-80 T 28-03-2018 IPR011444 Domain of unknown function DUF1549 MKLM6_RS05410 c4727a57da48c40b39fceb7fdef281cf 124 SUPERFAMILY SSF54427 1 119 2.0E-17 T 28-03-2018 IPR032710 NTF2-like domain MKLM6_RS05410 c4727a57da48c40b39fceb7fdef281cf 124 Gene3D G3DSA:3.10.450.50 2 122 1.7E-15 T 28-03-2018 MKLM6_RS05410 c4727a57da48c40b39fceb7fdef281cf 124 Pfam PF12680 SnoaL-like domain 11 81 2.8E-10 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MKLM6_RS12660 0ff488c70b9073307a0ada927370dcb3 400 Gene3D G3DSA:3.40.50.1100 204 396 1.1E-38 T 28-03-2018 MKLM6_RS12660 0ff488c70b9073307a0ada927370dcb3 400 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 86 100 - T 28-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MKLM6_RS12660 0ff488c70b9073307a0ada927370dcb3 400 Gene3D G3DSA:3.40.50.1100 14 74 5.9E-7 T 28-03-2018 MKLM6_RS12660 0ff488c70b9073307a0ada927370dcb3 400 Gene3D G3DSA:3.40.50.1100 75 203 1.3E-38 T 28-03-2018 MKLM6_RS12660 0ff488c70b9073307a0ada927370dcb3 400 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 7 396 53.669 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MKLM6_RS12660 0ff488c70b9073307a0ada927370dcb3 400 SUPERFAMILY SSF53686 8 393 6.02E-153 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MKLM6_RS12660 0ff488c70b9073307a0ada927370dcb3 400 PIRSF PIRSF001413 3 400 3.9E-164 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MKLM6_RS12660 0ff488c70b9073307a0ada927370dcb3 400 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 58 383 5.8E-47 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MKLM6_RS12660 0ff488c70b9073307a0ada927370dcb3 400 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 12 395 4.9E-195 T 28-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MKLM6_RS15595 ecfa6ac8ae785d9d98430e6792cb63fb 465 SUPERFAMILY SSF48163 297 460 2.09E-41 T 28-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MKLM6_RS15595 ecfa6ac8ae785d9d98430e6792cb63fb 465 Gene3D G3DSA:1.10.10.350 364 465 5.1E-24 T 28-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MKLM6_RS15595 ecfa6ac8ae785d9d98430e6792cb63fb 465 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 3 463 1.0E-184 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MKLM6_RS15595 ecfa6ac8ae785d9d98430e6792cb63fb 465 Gene3D G3DSA:3.40.50.620 1 125 1.1E-45 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS15595 ecfa6ac8ae785d9d98430e6792cb63fb 465 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 2 459 32.764 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MKLM6_RS15595 ecfa6ac8ae785d9d98430e6792cb63fb 465 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 9 20 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS15595 ecfa6ac8ae785d9d98430e6792cb63fb 465 Gene3D G3DSA:1.10.1160.10 230 311 5.0E-32 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 MKLM6_RS15595 ecfa6ac8ae785d9d98430e6792cb63fb 465 Gene3D G3DSA:1.10.8.70 316 359 2.8E-10 T 28-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 MKLM6_RS15595 ecfa6ac8ae785d9d98430e6792cb63fb 465 PRINTS PR00987 Glutamyl-tRNA synthetase signature 177 187 2.6E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MKLM6_RS15595 ecfa6ac8ae785d9d98430e6792cb63fb 465 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 2.6E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MKLM6_RS15595 ecfa6ac8ae785d9d98430e6792cb63fb 465 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 2.6E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MKLM6_RS15595 ecfa6ac8ae785d9d98430e6792cb63fb 465 PRINTS PR00987 Glutamyl-tRNA synthetase signature 193 201 2.6E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MKLM6_RS15595 ecfa6ac8ae785d9d98430e6792cb63fb 465 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 2.6E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MKLM6_RS15595 ecfa6ac8ae785d9d98430e6792cb63fb 465 Gene3D G3DSA:3.40.50.620 126 229 1.3E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS15595 ecfa6ac8ae785d9d98430e6792cb63fb 465 SUPERFAMILY SSF52374 3 294 4.02E-113 T 28-03-2018 MKLM6_RS15595 ecfa6ac8ae785d9d98430e6792cb63fb 465 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 3 303 1.4E-109 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 MKLM6_RS06275 7d7982a791fca2d4e33bd01c7602a471 296 SUPERFAMILY SSF101478 6 274 1.96E-75 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 MKLM6_RS06275 7d7982a791fca2d4e33bd01c7602a471 296 Gene3D G3DSA:1.10.4080.10 1 292 2.8E-74 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 MKLM6_RS06275 7d7982a791fca2d4e33bd01c7602a471 296 Pfam PF03747 ADP-ribosylglycohydrolase 11 265 3.0E-57 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 MKLM6_RS06275 7d7982a791fca2d4e33bd01c7602a471 296 TIGRFAM TIGR02662 dinitro_DRAG: ADP-ribosyl-[dinitrogen reductase] hydrolase 5 289 9.2E-130 T 28-03-2018 IPR013479 ADP-ribosyl-dinitrogen reductase hydrolase MKLM6_RS11400 da04edcf64353ba16c3fc1eea2d89172 632 Pfam PF12848 ABC transporter 222 296 9.7E-12 T 28-03-2018 IPR032781 ABC-transporter extension domain MKLM6_RS11400 da04edcf64353ba16c3fc1eea2d89172 632 SMART SM00382 342 513 8.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS11400 da04edcf64353ba16c3fc1eea2d89172 632 SMART SM00382 28 228 2.7E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS11400 da04edcf64353ba16c3fc1eea2d89172 632 Pfam PF16326 ABC transporter C-terminal domain 560 628 1.9E-20 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 MKLM6_RS11400 da04edcf64353ba16c3fc1eea2d89172 632 Gene3D G3DSA:3.40.50.300 282 550 1.2E-60 T 28-03-2018 MKLM6_RS11400 da04edcf64353ba16c3fc1eea2d89172 632 Gene3D G3DSA:3.40.50.300 4 281 7.7E-56 T 28-03-2018 MKLM6_RS11400 da04edcf64353ba16c3fc1eea2d89172 632 SUPERFAMILY SSF52540 4 237 6.8E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS11400 da04edcf64353ba16c3fc1eea2d89172 632 ProSitePatterns PS00211 ABC transporters family signature. 439 453 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS11400 da04edcf64353ba16c3fc1eea2d89172 632 Pfam PF00005 ABC transporter 19 183 3.3E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS11400 da04edcf64353ba16c3fc1eea2d89172 632 Pfam PF00005 ABC transporter 334 467 4.9E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS11400 da04edcf64353ba16c3fc1eea2d89172 632 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS11400 da04edcf64353ba16c3fc1eea2d89172 632 SUPERFAMILY SSF52540 313 516 1.89E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 840 873 3.4E-4 T 28-03-2018 IPR006530 YD repeat MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 667 708 3.1E-9 T 28-03-2018 IPR006530 YD repeat MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 735 773 1.3E-5 T 28-03-2018 IPR006530 YD repeat MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 529 561 0.002 T 28-03-2018 IPR006530 YD repeat MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 283 320 3.8E-6 T 28-03-2018 IPR006530 YD repeat MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 938 971 7.9E-4 T 28-03-2018 IPR006530 YD repeat MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 756 796 3.2E-7 T 28-03-2018 IPR006530 YD repeat MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 626 665 7.6E-5 T 28-03-2018 IPR006530 YD repeat MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 325 366 2.0E-5 T 28-03-2018 IPR006530 YD repeat MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 798 839 1.6E-7 T 28-03-2018 IPR006530 YD repeat MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1258 1333 1.8E-27 T 28-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 Gene3D G3DSA:1.10.530.10 1349 1496 7.3E-12 T 28-03-2018 MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 Pfam PF03527 RHS protein 1230 1261 3.5E-8 T 28-03-2018 IPR001826 RHS protein MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 Pfam PF05593 RHS Repeat 647 681 4.6E-8 T 28-03-2018 IPR031325 RHS repeat MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 Pfam PF05593 RHS Repeat 777 812 4.1E-8 T 28-03-2018 IPR031325 RHS repeat MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 Pfam PF05593 RHS Repeat 626 655 6.4E-8 T 28-03-2018 IPR031325 RHS repeat MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 Pfam PF05593 RHS Repeat 283 319 1.6E-5 T 28-03-2018 IPR031325 RHS repeat MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 Pfam PF05593 RHS Repeat 819 853 2.1E-5 T 28-03-2018 IPR031325 RHS repeat MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 Pfam PF05593 RHS Repeat 325 360 7.6E-7 T 28-03-2018 IPR031325 RHS repeat MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 Pfam PF05593 RHS Repeat 346 385 1.5E-5 T 28-03-2018 IPR031325 RHS repeat MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 Pfam PF05593 RHS Repeat 304 339 1.7E-6 T 28-03-2018 IPR031325 RHS repeat MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 Pfam PF05593 RHS Repeat 841 876 2.0E-6 T 28-03-2018 IPR031325 RHS repeat MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 Pfam PF05593 RHS Repeat 688 717 1.5E-5 T 28-03-2018 IPR031325 RHS repeat MKLM6_RS20095 3ed0fa8049b9df94ebf7a7c181032a83 1499 SUPERFAMILY SSF53955 1357 1493 3.71E-10 T 28-03-2018 IPR023346 Lysozyme-like domain MKLM6_RS12225 83f62772e77e521636115753078b5a5f 476 SUPERFAMILY SSF56349 115 417 2.38E-22 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS12225 83f62772e77e521636115753078b5a5f 476 Pfam PF00589 Phage integrase family 254 429 2.2E-7 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS12225 83f62772e77e521636115753078b5a5f 476 Gene3D G3DSA:1.10.150.130 107 229 0.0031 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal MKLM6_RS12225 83f62772e77e521636115753078b5a5f 476 Gene3D G3DSA:1.10.443.10 243 433 9.3E-18 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS13550 9c751750a2706ada8a6a9c95e06230a7 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 2.0E-27 T 28-03-2018 MKLM6_RS13550 9c751750a2706ada8a6a9c95e06230a7 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 1.7E-39 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS13550 9c751750a2706ada8a6a9c95e06230a7 89 Pfam PF00312 Ribosomal protein S15 8 88 2.2E-36 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS13550 9c751750a2706ada8a6a9c95e06230a7 89 Gene3D G3DSA:1.10.287.10 2 89 2.5E-34 T 28-03-2018 MKLM6_RS13550 9c751750a2706ada8a6a9c95e06230a7 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS13550 9c751750a2706ada8a6a9c95e06230a7 89 SMART SM01387 8 88 1.7E-51 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS13550 9c751750a2706ada8a6a9c95e06230a7 89 SUPERFAMILY SSF47060 3 89 4.71E-35 T 28-03-2018 IPR009068 S15/NS1, RNA-binding MKLM6_RS13550 9c751750a2706ada8a6a9c95e06230a7 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.273 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS00945 6143e7c778c7d4db8e0f7e4f8db31bc9 261 Gene3D G3DSA:3.40.50.150 1 261 6.4E-11 T 28-03-2018 MKLM6_RS00945 6143e7c778c7d4db8e0f7e4f8db31bc9 261 Pfam PF13489 Methyltransferase domain 33 108 1.5E-6 T 28-03-2018 MKLM6_RS00945 6143e7c778c7d4db8e0f7e4f8db31bc9 261 SUPERFAMILY SSF53335 22 164 2.56E-12 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS14185 092abf6302e043b2dc6a640393a0da8b 565 PRINTS PR00344 Bacterial sensor protein C-terminal signature 254 272 1.3E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14185 092abf6302e043b2dc6a640393a0da8b 565 PRINTS PR00344 Bacterial sensor protein C-terminal signature 219 233 1.3E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14185 092abf6302e043b2dc6a640393a0da8b 565 PRINTS PR00344 Bacterial sensor protein C-terminal signature 237 247 1.3E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14185 092abf6302e043b2dc6a640393a0da8b 565 PRINTS PR00344 Bacterial sensor protein C-terminal signature 278 291 1.3E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14185 092abf6302e043b2dc6a640393a0da8b 565 Pfam PF00072 Response regulator receiver domain 318 429 2.9E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14185 092abf6302e043b2dc6a640393a0da8b 565 SMART SM00388 71 137 1.2E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS14185 092abf6302e043b2dc6a640393a0da8b 565 Gene3D G3DSA:1.20.120.160 454 562 1.1E-12 T 28-03-2018 MKLM6_RS14185 092abf6302e043b2dc6a640393a0da8b 565 Gene3D G3DSA:3.30.450.20 16 74 8.2E-7 T 28-03-2018 MKLM6_RS14185 092abf6302e043b2dc6a640393a0da8b 565 SMART SM00448 316 429 6.7E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14185 092abf6302e043b2dc6a640393a0da8b 565 Gene3D G3DSA:3.30.565.10 141 302 8.8E-48 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14185 092abf6302e043b2dc6a640393a0da8b 565 SUPERFAMILY SSF52172 314 460 2.28E-34 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS14185 092abf6302e043b2dc6a640393a0da8b 565 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 183 292 5.0E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14185 092abf6302e043b2dc6a640393a0da8b 565 Pfam PF01627 Hpt domain 490 561 8.6E-8 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS14185 092abf6302e043b2dc6a640393a0da8b 565 SUPERFAMILY SSF47226 412 425 9.42E-16 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS14185 092abf6302e043b2dc6a640393a0da8b 565 SUPERFAMILY SSF47226 456 551 9.42E-16 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS14185 092abf6302e043b2dc6a640393a0da8b 565 SUPERFAMILY SSF47384 58 138 4.32E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS14185 092abf6302e043b2dc6a640393a0da8b 565 Gene3D G3DSA:3.40.50.2300 303 441 7.6E-36 T 28-03-2018 MKLM6_RS14185 092abf6302e043b2dc6a640393a0da8b 565 SUPERFAMILY SSF55874 126 295 4.98E-48 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14185 092abf6302e043b2dc6a640393a0da8b 565 Gene3D G3DSA:1.10.287.130 75 133 2.1E-17 T 28-03-2018 MKLM6_RS14185 092abf6302e043b2dc6a640393a0da8b 565 SMART SM00387 183 294 4.8E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14185 092abf6302e043b2dc6a640393a0da8b 565 Pfam PF00512 His Kinase A (phospho-acceptor) domain 71 137 5.6E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS02085 ead736f77b3b9547c225e76c31458b50 316 SUPERFAMILY SSF52440 3 123 2.36E-45 T 28-03-2018 IPR016185 Pre-ATP-grasp domain MKLM6_RS02085 ead736f77b3b9547c225e76c31458b50 316 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 125 298 1.6E-77 T 28-03-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 MKLM6_RS02085 ead736f77b3b9547c225e76c31458b50 316 Gene3D G3DSA:3.30.1490.20 139 192 1.7E-21 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MKLM6_RS02085 ead736f77b3b9547c225e76c31458b50 316 TIGRFAM TIGR01380 glut_syn: glutathione synthase 3 313 2.9E-138 T 28-03-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 MKLM6_RS02085 ead736f77b3b9547c225e76c31458b50 316 Hamap MF_00162 Glutathione synthetase [gshB]. 1 316 167.751 T 28-03-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 MKLM6_RS02085 ead736f77b3b9547c225e76c31458b50 316 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 3 121 3.0E-47 T 28-03-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 MKLM6_RS02085 ead736f77b3b9547c225e76c31458b50 316 Gene3D G3DSA:3.40.50.20 3 130 1.5E-51 T 28-03-2018 MKLM6_RS02085 ead736f77b3b9547c225e76c31458b50 316 SUPERFAMILY SSF56059 124 312 8.01E-57 T 28-03-2018 MKLM6_RS02085 ead736f77b3b9547c225e76c31458b50 316 Gene3D G3DSA:3.30.470.20 193 301 1.1E-16 T 28-03-2018 MKLM6_RS11095 dd3b8a189f55e760dcd85afd97b4ac78 646 Pfam PF00501 AMP-binding enzyme 82 519 3.2E-93 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MKLM6_RS11095 dd3b8a189f55e760dcd85afd97b4ac78 646 Pfam PF13193 AMP-binding enzyme C-terminal domain 528 606 1.9E-21 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MKLM6_RS11095 dd3b8a189f55e760dcd85afd97b4ac78 646 Gene3D G3DSA:3.30.300.30 515 646 1.3E-23 T 28-03-2018 MKLM6_RS11095 dd3b8a189f55e760dcd85afd97b4ac78 646 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 24 80 1.5E-20 T 28-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 MKLM6_RS11095 dd3b8a189f55e760dcd85afd97b4ac78 646 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 21 640 0.0 T 28-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 MKLM6_RS11095 dd3b8a189f55e760dcd85afd97b4ac78 646 Gene3D G3DSA:3.40.50.980 264 426 9.0E-39 T 28-03-2018 MKLM6_RS11095 dd3b8a189f55e760dcd85afd97b4ac78 646 Gene3D G3DSA:2.30.38.10 427 512 3.6E-10 T 28-03-2018 MKLM6_RS11095 dd3b8a189f55e760dcd85afd97b4ac78 646 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 2 642 52.293 T 28-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 MKLM6_RS11095 dd3b8a189f55e760dcd85afd97b4ac78 646 SUPERFAMILY SSF56801 12 641 2.22E-181 T 28-03-2018 MKLM6_RS11095 dd3b8a189f55e760dcd85afd97b4ac78 646 Gene3D G3DSA:3.40.50.980 73 263 1.6E-53 T 28-03-2018 MKLM6_RS11095 dd3b8a189f55e760dcd85afd97b4ac78 646 ProSitePatterns PS00455 Putative AMP-binding domain signature. 258 269 - T 28-03-2018 IPR020845 AMP-binding, conserved site MKLM6_RS18440 2718b09e13d2d9f3c46979215b50369c 216 SUPERFAMILY SSF50447 1 211 8.83E-77 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain MKLM6_RS18440 2718b09e13d2d9f3c46979215b50369c 216 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 206 2.8E-85 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18440 2718b09e13d2d9f3c46979215b50369c 216 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 210 38.002 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18440 2718b09e13d2d9f3c46979215b50369c 216 Gene3D G3DSA:4.10.960.10 58 168 8.3E-29 T 28-03-2018 MKLM6_RS18440 2718b09e13d2d9f3c46979215b50369c 216 Pfam PF00297 Ribosomal protein L3 102 184 4.8E-13 T 28-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18440 2718b09e13d2d9f3c46979215b50369c 216 ProSitePatterns PS00474 Ribosomal protein L3 signature. 104 127 - T 28-03-2018 IPR019926 Ribosomal protein L3, conserved site MKLM6_RS16300 b8fb4aa3aa37bf5cbc5f7f77c03d3160 641 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 330 336 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MKLM6_RS16300 b8fb4aa3aa37bf5cbc5f7f77c03d3160 641 Gene3D G3DSA:3.40.50.150 212 610 1.8E-46 T 28-03-2018 MKLM6_RS16300 b8fb4aa3aa37bf5cbc5f7f77c03d3160 641 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 327 339 2.5E-13 T 28-03-2018 MKLM6_RS16300 b8fb4aa3aa37bf5cbc5f7f77c03d3160 641 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 238 252 2.5E-13 T 28-03-2018 MKLM6_RS16300 b8fb4aa3aa37bf5cbc5f7f77c03d3160 641 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 214 230 2.5E-13 T 28-03-2018 MKLM6_RS16300 b8fb4aa3aa37bf5cbc5f7f77c03d3160 641 Pfam PF02384 N-6 DNA Methylase 195 455 2.3E-54 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 MKLM6_RS16300 b8fb4aa3aa37bf5cbc5f7f77c03d3160 641 Pfam PF12161 HsdM N-terminal domain 19 176 1.2E-10 T 28-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain MKLM6_RS16300 b8fb4aa3aa37bf5cbc5f7f77c03d3160 641 SUPERFAMILY SSF53335 113 556 2.21E-92 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS16300 b8fb4aa3aa37bf5cbc5f7f77c03d3160 641 SUPERFAMILY SSF53335 18 86 2.21E-92 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS03720 e14801e8ad5c3b426444145f02c798ea 212 Gene3D G3DSA:3.20.19.10 1 182 1.1E-47 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MKLM6_RS03720 e14801e8ad5c3b426444145f02c798ea 212 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 208 44.004 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 MKLM6_RS03720 e14801e8ad5c3b426444145f02c798ea 212 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 194 7.2E-80 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 MKLM6_RS03720 e14801e8ad5c3b426444145f02c798ea 212 Pfam PF00694 Aconitase C-terminal domain 1 132 5.3E-36 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 MKLM6_RS03720 e14801e8ad5c3b426444145f02c798ea 212 SUPERFAMILY SSF52016 1 201 6.28E-62 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MKLM6_RS14810 cd675890828fb1a8c2ec57950726f250 212 PRINTS PR00773 GrpE protein signature 94 109 5.3E-25 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MKLM6_RS14810 cd675890828fb1a8c2ec57950726f250 212 PRINTS PR00773 GrpE protein signature 149 164 5.3E-25 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MKLM6_RS14810 cd675890828fb1a8c2ec57950726f250 212 PRINTS PR00773 GrpE protein signature 176 195 5.3E-25 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MKLM6_RS14810 cd675890828fb1a8c2ec57950726f250 212 PRINTS PR00773 GrpE protein signature 66 82 5.3E-25 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MKLM6_RS14810 cd675890828fb1a8c2ec57950726f250 212 SUPERFAMILY SSF58014 43 140 6.02E-24 T 28-03-2018 MKLM6_RS14810 cd675890828fb1a8c2ec57950726f250 212 ProSitePatterns PS01071 grpE protein signature. 152 195 - T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MKLM6_RS14810 cd675890828fb1a8c2ec57950726f250 212 SUPERFAMILY SSF51064 142 198 1.05E-19 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 MKLM6_RS14810 cd675890828fb1a8c2ec57950726f250 212 Hamap MF_01151 Protein GrpE [grpE]. 4 197 20.026 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MKLM6_RS14810 cd675890828fb1a8c2ec57950726f250 212 Gene3D G3DSA:3.90.20.20 2 140 6.0E-24 T 28-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 MKLM6_RS14810 cd675890828fb1a8c2ec57950726f250 212 Gene3D G3DSA:2.30.22.10 142 197 1.2E-21 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 MKLM6_RS14810 cd675890828fb1a8c2ec57950726f250 212 Pfam PF01025 GrpE 37 197 1.5E-48 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MKLM6_RS20875 b1139f4bc8dba2694f247b17f26f6ea1 211 TIGRFAM TIGR01083 nth: endonuclease III 5 194 6.7E-85 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 MKLM6_RS20875 b1139f4bc8dba2694f247b17f26f6ea1 211 PIRSF PIRSF001435 1 210 2.5E-57 T 28-03-2018 MKLM6_RS20875 b1139f4bc8dba2694f247b17f26f6ea1 211 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 168 7.1E-20 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MKLM6_RS20875 b1139f4bc8dba2694f247b17f26f6ea1 211 Pfam PF00633 Helix-hairpin-helix motif 100 127 2.6E-7 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 MKLM6_RS20875 b1139f4bc8dba2694f247b17f26f6ea1 211 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 187 203 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MKLM6_RS20875 b1139f4bc8dba2694f247b17f26f6ea1 211 SMART SM00525 186 206 1.7E-4 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 MKLM6_RS20875 b1139f4bc8dba2694f247b17f26f6ea1 211 SMART SM00478 38 185 8.4E-56 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MKLM6_RS20875 b1139f4bc8dba2694f247b17f26f6ea1 211 Hamap MF_00942 Endonuclease III [nth]. 1 209 37.14 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 MKLM6_RS20875 b1139f4bc8dba2694f247b17f26f6ea1 211 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 MKLM6_RS20875 b1139f4bc8dba2694f247b17f26f6ea1 211 SUPERFAMILY SSF48150 3 208 8.95E-72 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MKLM6_RS20875 b1139f4bc8dba2694f247b17f26f6ea1 211 Gene3D G3DSA:1.10.1670.10 118 210 2.0E-31 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 MKLM6_RS20875 b1139f4bc8dba2694f247b17f26f6ea1 211 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 187 203 2.2E-4 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 MKLM6_RS20875 b1139f4bc8dba2694f247b17f26f6ea1 211 Gene3D G3DSA:1.10.340.30 20 117 1.2E-23 T 28-03-2018 MKLM6_RS16225 462f0e689d23ba9c2f82053aa059f961 339 SMART SM00382 41 185 8.5E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS16225 462f0e689d23ba9c2f82053aa059f961 339 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 44 177 3.4E-27 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 MKLM6_RS16225 462f0e689d23ba9c2f82053aa059f961 339 Gene3D G3DSA:1.10.8.300 227 336 4.1E-22 T 28-03-2018 MKLM6_RS16225 462f0e689d23ba9c2f82053aa059f961 339 Gene3D G3DSA:3.40.50.300 2 226 1.4E-20 T 28-03-2018 MKLM6_RS16225 462f0e689d23ba9c2f82053aa059f961 339 PIRSF PIRSF002849 1 339 2.0E-79 T 28-03-2018 MKLM6_RS16225 462f0e689d23ba9c2f82053aa059f961 339 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 114 132 9.5E-6 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 MKLM6_RS16225 462f0e689d23ba9c2f82053aa059f961 339 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 45 63 9.5E-6 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 MKLM6_RS16225 462f0e689d23ba9c2f82053aa059f961 339 SUPERFAMILY SSF52540 238 311 1.19E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS16225 462f0e689d23ba9c2f82053aa059f961 339 SUPERFAMILY SSF52540 8 193 1.19E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS08285 1e23cbbd3c275b9717e04e6afeed45ff 534 TIGRFAM TIGR02373 photo_yellow: photoactive yellow protein 412 534 7.1E-54 T 28-03-2018 IPR012130 Photoactive yellow-protein GO:0007602|GO:0009881|GO:0018298 MKLM6_RS08285 1e23cbbd3c275b9717e04e6afeed45ff 534 Pfam PF00989 PAS fold 430 530 9.2E-10 T 28-03-2018 IPR013767 PAS fold GO:0006355 MKLM6_RS08285 1e23cbbd3c275b9717e04e6afeed45ff 534 SUPERFAMILY SSF58104 97 406 4.58E-74 T 28-03-2018 MKLM6_RS08285 1e23cbbd3c275b9717e04e6afeed45ff 534 Gene3D G3DSA:1.10.287.950 68 171 4.8E-4 T 28-03-2018 MKLM6_RS08285 1e23cbbd3c275b9717e04e6afeed45ff 534 SMART SM00304 78 129 5.9E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS08285 1e23cbbd3c275b9717e04e6afeed45ff 534 SMART SM00283 144 405 6.4E-67 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS08285 1e23cbbd3c275b9717e04e6afeed45ff 534 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 190 372 4.1E-42 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS08285 1e23cbbd3c275b9717e04e6afeed45ff 534 Gene3D G3DSA:1.10.287.950 172 369 6.9E-51 T 28-03-2018 MKLM6_RS08285 1e23cbbd3c275b9717e04e6afeed45ff 534 SUPERFAMILY SSF55785 425 531 3.14E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS08285 1e23cbbd3c275b9717e04e6afeed45ff 534 Gene3D G3DSA:3.30.450.20 370 534 2.2E-9 T 28-03-2018 MKLM6_RS05035 28f5375c6619c5b66d9b90be82de88aa 428 SUPERFAMILY SSF103473 6 417 3.79E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain MKLM6_RS05035 28f5375c6619c5b66d9b90be82de88aa 428 Gene3D G3DSA:1.20.1250.20 217 426 2.5E-21 T 28-03-2018 MKLM6_RS05035 28f5375c6619c5b66d9b90be82de88aa 428 ProSitePatterns PS00217 Sugar transport proteins signature 2. 119 144 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MKLM6_RS05035 28f5375c6619c5b66d9b90be82de88aa 428 Gene3D G3DSA:1.20.1250.20 1 216 5.7E-24 T 28-03-2018 MKLM6_RS05035 28f5375c6619c5b66d9b90be82de88aa 428 Pfam PF00083 Sugar (and other) transporter 225 407 2.1E-8 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MKLM6_RS05035 28f5375c6619c5b66d9b90be82de88aa 428 Pfam PF00083 Sugar (and other) transporter 16 216 6.0E-25 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MKLM6_RS15355 021e0d38ff35d790f19bf13ebf57eda8 378 Gene3D G3DSA:3.40.50.2000 1 180 1.6E-13 T 28-03-2018 MKLM6_RS15355 021e0d38ff35d790f19bf13ebf57eda8 378 Pfam PF13439 Glycosyltransferase Family 4 18 177 1.5E-17 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MKLM6_RS15355 021e0d38ff35d790f19bf13ebf57eda8 378 Gene3D G3DSA:3.40.50.2000 181 362 2.1E-43 T 28-03-2018 MKLM6_RS15355 021e0d38ff35d790f19bf13ebf57eda8 378 Pfam PF00534 Glycosyl transferases group 1 198 357 4.4E-33 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 MKLM6_RS15355 021e0d38ff35d790f19bf13ebf57eda8 378 TIGRFAM TIGR03088 stp2: sugar transferase, PEP-CTERM/EpsH1 system associated 7 376 6.3E-152 T 28-03-2018 IPR017522 Sugar transferase, PEP-CTERM, Stp2 MKLM6_RS15355 021e0d38ff35d790f19bf13ebf57eda8 378 SUPERFAMILY SSF53756 9 376 3.84E-77 T 28-03-2018 MKLM6_RS15255 d9fa702913f27f9661218b85cac486a8 215 SUPERFAMILY SSF52540 23 194 7.09E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS15255 d9fa702913f27f9661218b85cac486a8 215 Gene3D G3DSA:3.40.50.300 24 202 6.6E-49 T 28-03-2018 MKLM6_RS15255 d9fa702913f27f9661218b85cac486a8 215 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 26 198 37.159 T 28-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 MKLM6_RS15255 d9fa702913f27f9661218b85cac486a8 215 Pfam PF01583 Adenylylsulphate kinase 27 180 4.0E-68 T 28-03-2018 MKLM6_RS15255 d9fa702913f27f9661218b85cac486a8 215 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 10 194 7.8E-81 T 28-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 MKLM6_RS07175 ecd98059b3d014f4c25fa57055e1d0c8 599 Gene3D G3DSA:3.40.50.300 1 187 7.0E-37 T 28-03-2018 MKLM6_RS07175 ecd98059b3d014f4c25fa57055e1d0c8 599 TIGRFAM TIGR01393 lepA: elongation factor 4 4 597 3.7E-299 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 MKLM6_RS07175 ecd98059b3d014f4c25fa57055e1d0c8 599 Gene3D G3DSA:3.30.70.870 290 369 2.2E-26 T 28-03-2018 MKLM6_RS07175 ecd98059b3d014f4c25fa57055e1d0c8 599 SUPERFAMILY SSF54980 401 495 5.76E-26 T 28-03-2018 IPR035647 EF-G domain III/V-like MKLM6_RS07175 ecd98059b3d014f4c25fa57055e1d0c8 599 SMART SM00838 400 488 6.9E-4 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like MKLM6_RS07175 ecd98059b3d014f4c25fa57055e1d0c8 599 Gene3D G3DSA:2.40.30.10 190 289 4.9E-25 T 28-03-2018 MKLM6_RS07175 ecd98059b3d014f4c25fa57055e1d0c8 599 Pfam PF00679 Elongation factor G C-terminus 401 486 9.5E-22 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like MKLM6_RS07175 ecd98059b3d014f4c25fa57055e1d0c8 599 Hamap MF_00071 Elongation factor 4 [lepA]. 1 599 303.713 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 MKLM6_RS07175 ecd98059b3d014f4c25fa57055e1d0c8 599 Pfam PF06421 GTP-binding protein LepA C-terminus 489 595 1.5E-51 T 28-03-2018 IPR013842 GTP-binding protein LepA, C-terminal MKLM6_RS07175 ecd98059b3d014f4c25fa57055e1d0c8 599 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 175 7.0E-18 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MKLM6_RS07175 ecd98059b3d014f4c25fa57055e1d0c8 599 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site MKLM6_RS07175 ecd98059b3d014f4c25fa57055e1d0c8 599 SUPERFAMILY SSF54980 294 372 6.83E-18 T 28-03-2018 IPR035647 EF-G domain III/V-like MKLM6_RS07175 ecd98059b3d014f4c25fa57055e1d0c8 599 Gene3D G3DSA:3.30.70.240 396 551 4.6E-29 T 28-03-2018 MKLM6_RS07175 ecd98059b3d014f4c25fa57055e1d0c8 599 SUPERFAMILY SSF52540 2 207 1.06E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS07175 ecd98059b3d014f4c25fa57055e1d0c8 599 SUPERFAMILY SSF50447 167 290 5.82E-28 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain MKLM6_RS07175 ecd98059b3d014f4c25fa57055e1d0c8 599 Pfam PF00009 Elongation factor Tu GTP binding domain 4 183 1.7E-50 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS07175 ecd98059b3d014f4c25fa57055e1d0c8 599 PRINTS PR00315 GTP-binding elongation factor signature 51 59 3.3E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS07175 ecd98059b3d014f4c25fa57055e1d0c8 599 PRINTS PR00315 GTP-binding elongation factor signature 8 21 3.3E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS07175 ecd98059b3d014f4c25fa57055e1d0c8 599 PRINTS PR00315 GTP-binding elongation factor signature 76 86 3.3E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS07175 ecd98059b3d014f4c25fa57055e1d0c8 599 PRINTS PR00315 GTP-binding elongation factor signature 128 137 3.3E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS07175 ecd98059b3d014f4c25fa57055e1d0c8 599 PRINTS PR00315 GTP-binding elongation factor signature 92 103 3.3E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS07175 ecd98059b3d014f4c25fa57055e1d0c8 599 Pfam PF03144 Elongation factor Tu domain 2 207 277 8.9E-10 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MKLM6_RS05310 5cc1b3269e4257c81827d98b2ccb1f12 121 SUPERFAMILY SSF116734 6 103 5.56E-11 T 28-03-2018 MKLM6_RS05310 5cc1b3269e4257c81827d98b2ccb1f12 121 Gene3D G3DSA:3.90.220.20 3 120 1.0E-10 T 28-03-2018 MKLM6_RS05805 c9301c1a8f8be774d9246b552b64dafb 634 SMART SM00052 402 632 2.2E-9 T 28-03-2018 IPR001633 EAL domain MKLM6_RS05805 c9301c1a8f8be774d9246b552b64dafb 634 Pfam PF00990 Diguanylate cyclase, GGDEF domain 239 389 2.3E-9 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS05805 c9301c1a8f8be774d9246b552b64dafb 634 Gene3D G3DSA:3.20.20.450 395 633 2.7E-36 T 28-03-2018 IPR001633 EAL domain MKLM6_RS05805 c9301c1a8f8be774d9246b552b64dafb 634 SUPERFAMILY SSF141868 423 629 3.66E-33 T 28-03-2018 IPR001633 EAL domain MKLM6_RS05805 c9301c1a8f8be774d9246b552b64dafb 634 Pfam PF00563 EAL domain 415 629 3.1E-29 T 28-03-2018 IPR001633 EAL domain MKLM6_RS05805 c9301c1a8f8be774d9246b552b64dafb 634 SUPERFAMILY SSF55073 242 394 7.85E-12 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS05805 c9301c1a8f8be774d9246b552b64dafb 634 Gene3D G3DSA:3.30.70.270 232 394 6.4E-16 T 28-03-2018 MKLM6_RS05805 c9301c1a8f8be774d9246b552b64dafb 634 Pfam PF16448 LapD/MoxY periplasmic domain 23 146 7.6E-39 T 28-03-2018 IPR032244 LapD/MoxY, periplasmic domain MKLM6_RS05805 c9301c1a8f8be774d9246b552b64dafb 634 SMART SM00267 227 394 3.9E-6 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS17975 de554de3645f2a27bbebc8eb0634fb56 130 Pfam PF13436 Glycine-zipper domain 63 104 6.1E-7 T 28-03-2018 IPR025693 Glycine-zipper-containing OmpA-like membrane domain MKLM6_RS18260 b814ce28df609696821ac177ade687d7 144 ProSitePatterns PS00194 Thioredoxin family active site. 61 79 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MKLM6_RS18260 b814ce28df609696821ac177ade687d7 144 PIRSF PIRSF000077 38 144 2.2E-31 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MKLM6_RS18260 b814ce28df609696821ac177ade687d7 144 TIGRFAM TIGR01068 thioredoxin: thioredoxin 45 142 4.9E-32 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MKLM6_RS18260 b814ce28df609696821ac177ade687d7 144 Gene3D G3DSA:3.40.30.10 38 144 8.3E-30 T 28-03-2018 MKLM6_RS18260 b814ce28df609696821ac177ade687d7 144 Pfam PF00085 Thioredoxin 42 142 4.3E-28 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 MKLM6_RS18260 b814ce28df609696821ac177ade687d7 144 PRINTS PR00421 Thioredoxin family signature 108 119 9.9E-9 T 28-03-2018 MKLM6_RS18260 b814ce28df609696821ac177ade687d7 144 PRINTS PR00421 Thioredoxin family signature 60 68 9.9E-9 T 28-03-2018 MKLM6_RS18260 b814ce28df609696821ac177ade687d7 144 PRINTS PR00421 Thioredoxin family signature 68 77 9.9E-9 T 28-03-2018 MKLM6_RS18260 b814ce28df609696821ac177ade687d7 144 SUPERFAMILY SSF52833 26 143 1.79E-35 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 Hamap MF_00054_B Elongation factor G [fusA]. 6 696 110.185 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 PRINTS PR00315 GTP-binding elongation factor signature 58 66 5.7E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 PRINTS PR00315 GTP-binding elongation factor signature 101 112 5.7E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 PRINTS PR00315 GTP-binding elongation factor signature 85 95 5.7E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 PRINTS PR00315 GTP-binding elongation factor signature 137 146 5.7E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 PRINTS PR00315 GTP-binding elongation factor signature 12 25 5.7E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 SUPERFAMILY SSF52540 6 288 3.47E-109 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 TIGRFAM TIGR00484 EF-G: translation elongation factor G 2 695 0.0 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 Gene3D G3DSA:3.30.70.240 619 696 1.7E-30 T 28-03-2018 MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 SUPERFAMILY SSF54980 407 485 2.52E-25 T 28-03-2018 IPR035647 EF-G domain III/V-like MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 SMART SM00838 605 692 2.1E-55 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 Gene3D G3DSA:3.30.70.870 400 497 2.3E-38 T 28-03-2018 MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 SUPERFAMILY SSF54980 605 695 8.15E-28 T 28-03-2018 IPR035647 EF-G domain III/V-like MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 SMART SM00889 485 603 3.2E-73 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 Pfam PF00679 Elongation factor G C-terminus 605 690 1.2E-28 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 Gene3D G3DSA:2.40.30.10 281 399 4.6E-30 T 28-03-2018 MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 Pfam PF14492 Elongation Factor G, domain II 409 482 2.8E-35 T 28-03-2018 MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 Pfam PF03764 Elongation factor G, domain IV 484 602 2.8E-48 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 184 6.9E-33 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 1.6E-68 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 SUPERFAMILY SSF50447 271 409 3.53E-36 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 Gene3D G3DSA:3.40.50.300 1 280 2.4E-58 T 28-03-2018 MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 Pfam PF03144 Elongation factor Tu domain 2 329 396 3.0E-16 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 SUPERFAMILY SSF54211 484 604 6.07E-46 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 Gene3D G3DSA:3.30.230.10 498 618 5.2E-44 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MKLM6_RS18455 76c608f92126c08f0ab4ede2af8eb354 697 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 Pfam PF13181 Tetratricopeptide repeat 409 440 6.0E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 Pfam PF13181 Tetratricopeptide repeat 451 474 0.16 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 SUPERFAMILY SSF48452 42 265 4.93E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 SUPERFAMILY SSF48452 345 501 1.15E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 SMART SM00028 510 543 0.24 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 SMART SM00028 647 680 51.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 SMART SM00028 442 475 54.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 SMART SM00028 408 441 0.18 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 SMART SM00028 612 646 400.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 SMART SM00028 66 99 27.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 SMART SM00028 544 577 95.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 SMART SM00028 168 201 33.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 SMART SM00028 202 235 400.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 SMART SM00028 134 167 350.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 SMART SM00028 750 783 6.5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 SMART SM00028 100 133 13.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 SUPERFAMILY SSF48452 473 682 4.13E-23 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 Gene3D G3DSA:1.25.40.10 299 465 6.5E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 Gene3D G3DSA:1.25.40.10 596 673 3.4E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 Pfam PF13174 Tetratricopeptide repeat 654 679 0.15 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 Gene3D G3DSA:1.25.40.10 24 100 1.9E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 Pfam PF14559 Tetratricopeptide repeat 113 177 3.4E-7 T 28-03-2018 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 Gene3D G3DSA:1.25.40.10 674 788 1.4E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 SUPERFAMILY SSF48452 638 782 6.2E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 Gene3D G3DSA:1.25.40.10 152 286 2.5E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 Gene3D G3DSA:1.25.40.10 101 151 7.4E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 Gene3D G3DSA:1.25.40.10 466 488 0.0018 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 Gene3D G3DSA:1.25.40.10 489 595 3.0E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 Pfam PF13432 Tetratricopeptide repeat 723 777 1.7E-6 T 28-03-2018 MKLM6_RS15405 3a3967ead579c02b2a6c65f214adb3d9 806 Pfam PF13432 Tetratricopeptide repeat 514 577 1.3E-4 T 28-03-2018 MKLM6_RS02065 e989e93a04edc446673297ee454f84d2 446 SUPERFAMILY SSF50494 30 250 7.54E-67 T 28-03-2018 IPR009003 Peptidase S1, PA clan MKLM6_RS02065 e989e93a04edc446673297ee454f84d2 446 Gene3D G3DSA:2.40.10.10 29 136 5.1E-34 T 28-03-2018 MKLM6_RS02065 e989e93a04edc446673297ee454f84d2 446 PRINTS PR00834 HtrA/DegQ protease family signature 156 180 1.3E-56 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MKLM6_RS02065 e989e93a04edc446673297ee454f84d2 446 PRINTS PR00834 HtrA/DegQ protease family signature 299 311 1.3E-56 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MKLM6_RS02065 e989e93a04edc446673297ee454f84d2 446 PRINTS PR00834 HtrA/DegQ protease family signature 95 107 1.3E-56 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MKLM6_RS02065 e989e93a04edc446673297ee454f84d2 446 PRINTS PR00834 HtrA/DegQ protease family signature 116 136 1.3E-56 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MKLM6_RS02065 e989e93a04edc446673297ee454f84d2 446 PRINTS PR00834 HtrA/DegQ protease family signature 191 208 1.3E-56 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MKLM6_RS02065 e989e93a04edc446673297ee454f84d2 446 PRINTS PR00834 HtrA/DegQ protease family signature 213 230 1.3E-56 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MKLM6_RS02065 e989e93a04edc446673297ee454f84d2 446 Pfam PF13365 Trypsin-like peptidase domain 85 220 9.9E-33 T 28-03-2018 MKLM6_RS02065 e989e93a04edc446673297ee454f84d2 446 SMART SM00228 259 342 1.1E-15 T 28-03-2018 IPR001478 PDZ domain GO:0005515 MKLM6_RS02065 e989e93a04edc446673297ee454f84d2 446 SMART SM00228 371 438 2.6E-7 T 28-03-2018 IPR001478 PDZ domain GO:0005515 MKLM6_RS02065 e989e93a04edc446673297ee454f84d2 446 Pfam PF13180 PDZ domain 260 350 6.7E-16 T 28-03-2018 IPR001478 PDZ domain GO:0005515 MKLM6_RS02065 e989e93a04edc446673297ee454f84d2 446 Gene3D G3DSA:2.40.10.10 137 248 5.2E-42 T 28-03-2018 MKLM6_RS02065 e989e93a04edc446673297ee454f84d2 446 SUPERFAMILY SSF50156 218 342 4.99E-26 T 28-03-2018 IPR001478 PDZ domain GO:0005515 MKLM6_RS02065 e989e93a04edc446673297ee454f84d2 446 SUPERFAMILY SSF50156 374 445 1.29E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 MKLM6_RS02065 e989e93a04edc446673297ee454f84d2 446 Gene3D G3DSA:2.30.42.10 254 362 9.6E-27 T 28-03-2018 MKLM6_RS02065 e989e93a04edc446673297ee454f84d2 446 Gene3D G3DSA:2.30.42.10 363 446 3.8E-12 T 28-03-2018 MKLM6_RS02065 e989e93a04edc446673297ee454f84d2 446 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 32 444 9.3E-150 T 28-03-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 MKLM6_RS06645 cbbb5d9067706e5c172f08ac6e8f780c 267 SUPERFAMILY SSF117987 29 102 4.18E-11 T 28-03-2018 MKLM6_RS06645 cbbb5d9067706e5c172f08ac6e8f780c 267 SMART SM01101 29 266 2.6E-62 T 28-03-2018 IPR010179 CRISPR-associated protein Cse3 MKLM6_RS06645 cbbb5d9067706e5c172f08ac6e8f780c 267 SUPERFAMILY SSF117987 113 136 3.66E-25 T 28-03-2018 MKLM6_RS06645 cbbb5d9067706e5c172f08ac6e8f780c 267 SUPERFAMILY SSF117987 182 266 3.66E-25 T 28-03-2018 MKLM6_RS06645 cbbb5d9067706e5c172f08ac6e8f780c 267 Pfam PF08798 CRISPR associated protein 29 266 7.8E-55 T 28-03-2018 IPR010179 CRISPR-associated protein Cse3 MKLM6_RS06645 cbbb5d9067706e5c172f08ac6e8f780c 267 Gene3D G3DSA:3.30.70.1210 112 266 1.1E-28 T 28-03-2018 MKLM6_RS06645 cbbb5d9067706e5c172f08ac6e8f780c 267 TIGRFAM TIGR01907 casE_Cse3: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI 29 266 3.0E-45 T 28-03-2018 IPR010179 CRISPR-associated protein Cse3 MKLM6_RS06645 cbbb5d9067706e5c172f08ac6e8f780c 267 Gene3D G3DSA:3.30.70.1200 25 107 6.2E-17 T 28-03-2018 MKLM6_RS18350 40218b7ed9b78464e87f4f95abbee283 61 SUPERFAMILY SSF55129 5 61 4.58E-16 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain MKLM6_RS18350 40218b7ed9b78464e87f4f95abbee283 61 Pfam PF00327 Ribosomal protein L30p/L7e 8 54 3.1E-13 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain MKLM6_RS18350 40218b7ed9b78464e87f4f95abbee283 61 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 7 60 3.2E-15 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18350 40218b7ed9b78464e87f4f95abbee283 61 Gene3D G3DSA:3.30.1390.20 6 60 2.9E-17 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain MKLM6_RS18350 40218b7ed9b78464e87f4f95abbee283 61 PIRSF PIRSF002211 1 61 2.6E-19 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18350 40218b7ed9b78464e87f4f95abbee283 61 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 3 60 17.327 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS13390 5d924965119a6baaec3f1d1903daedd7 715 SUPERFAMILY SSF52172 9 142 8.68E-38 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS13390 5d924965119a6baaec3f1d1903daedd7 715 Pfam PF00990 Diguanylate cyclase, GGDEF domain 266 434 1.5E-30 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS13390 5d924965119a6baaec3f1d1903daedd7 715 Pfam PF00072 Response regulator receiver domain 10 121 1.2E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS13390 5d924965119a6baaec3f1d1903daedd7 715 Gene3D G3DSA:3.30.70.270 262 441 3.2E-41 T 28-03-2018 MKLM6_RS13390 5d924965119a6baaec3f1d1903daedd7 715 Pfam PF00563 EAL domain 455 691 7.4E-73 T 28-03-2018 IPR001633 EAL domain MKLM6_RS13390 5d924965119a6baaec3f1d1903daedd7 715 Gene3D G3DSA:3.20.20.450 442 700 3.9E-100 T 28-03-2018 IPR001633 EAL domain MKLM6_RS13390 5d924965119a6baaec3f1d1903daedd7 715 SUPERFAMILY SSF141868 454 701 1.7E-90 T 28-03-2018 IPR001633 EAL domain MKLM6_RS13390 5d924965119a6baaec3f1d1903daedd7 715 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 264 437 2.7E-26 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS13390 5d924965119a6baaec3f1d1903daedd7 715 SMART SM00267 254 439 7.6E-34 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS13390 5d924965119a6baaec3f1d1903daedd7 715 Gene3D G3DSA:3.30.450.20 136 261 4.3E-14 T 28-03-2018 MKLM6_RS13390 5d924965119a6baaec3f1d1903daedd7 715 Gene3D G3DSA:3.40.50.2300 1 135 1.8E-36 T 28-03-2018 MKLM6_RS13390 5d924965119a6baaec3f1d1903daedd7 715 SUPERFAMILY SSF55785 191 262 5.58E-8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13390 5d924965119a6baaec3f1d1903daedd7 715 SMART SM00052 449 696 1.8E-124 T 28-03-2018 IPR001633 EAL domain MKLM6_RS13390 5d924965119a6baaec3f1d1903daedd7 715 SUPERFAMILY SSF55073 270 441 2.43E-33 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS13390 5d924965119a6baaec3f1d1903daedd7 715 SMART SM00448 8 121 7.2E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS19265 d880960b7ec7737486446d3f282b9696 439 Gene3D G3DSA:2.40.30.10 333 439 2.0E-22 T 28-03-2018 MKLM6_RS19265 d880960b7ec7737486446d3f282b9696 439 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 76 91 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site MKLM6_RS19265 d880960b7ec7737486446d3f282b9696 439 SUPERFAMILY SSF50465 335 438 1.29E-26 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MKLM6_RS19265 d880960b7ec7737486446d3f282b9696 439 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 23 437 5.1E-159 T 28-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MKLM6_RS19265 d880960b7ec7737486446d3f282b9696 439 PRINTS PR00315 GTP-binding elongation factor signature 83 91 2.6E-12 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS19265 d880960b7ec7737486446d3f282b9696 439 PRINTS PR00315 GTP-binding elongation factor signature 24 37 2.6E-12 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS19265 d880960b7ec7737486446d3f282b9696 439 PRINTS PR00315 GTP-binding elongation factor signature 156 165 2.6E-12 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS19265 d880960b7ec7737486446d3f282b9696 439 PRINTS PR00315 GTP-binding elongation factor signature 119 130 2.6E-12 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS19265 d880960b7ec7737486446d3f282b9696 439 PRINTS PR00315 GTP-binding elongation factor signature 103 113 2.6E-12 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS19265 d880960b7ec7737486446d3f282b9696 439 Pfam PF00009 Elongation factor Tu GTP binding domain 23 212 5.5E-40 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS19265 d880960b7ec7737486446d3f282b9696 439 SUPERFAMILY SSF50447 234 332 1.75E-17 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain MKLM6_RS19265 d880960b7ec7737486446d3f282b9696 439 Gene3D G3DSA:3.40.50.300 13 219 1.8E-37 T 28-03-2018 MKLM6_RS19265 d880960b7ec7737486446d3f282b9696 439 Gene3D G3DSA:2.40.30.10 220 331 4.3E-19 T 28-03-2018 MKLM6_RS19265 d880960b7ec7737486446d3f282b9696 439 SUPERFAMILY SSF52540 20 246 2.27E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS18430 ada1de10cdea16664eb9649a8b84e70c 99 Pfam PF00276 Ribosomal protein L23 10 95 5.3E-33 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18430 ada1de10cdea16664eb9649a8b84e70c 99 SUPERFAMILY SSF54189 6 94 6.12E-31 T 28-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18430 ada1de10cdea16664eb9649a8b84e70c 99 Gene3D G3DSA:3.30.70.330 6 99 2.8E-30 T 28-03-2018 MKLM6_RS18430 ada1de10cdea16664eb9649a8b84e70c 99 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 9 99 22.771 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 MKLM6_RS17575 68de3574dec6548b12737d65768afd17 498 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 59 442 1.1E-92 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 MKLM6_RS17575 68de3574dec6548b12737d65768afd17 498 SUPERFAMILY SSF56317 218 455 6.8E-39 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS17575 68de3574dec6548b12737d65768afd17 498 Gene3D G3DSA:3.60.110.10 202 462 7.3E-38 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS17575 68de3574dec6548b12737d65768afd17 498 Pfam PF00795 Carbon-nitrogen hydrolase 221 456 3.3E-27 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS17575 68de3574dec6548b12737d65768afd17 498 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 6 480 21.65 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 MKLM6_RS19580 e38f7570143a642ac4c0f634581e8686 319 SUPERFAMILY SSF55120 98 315 2.72E-67 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS19580 e38f7570143a642ac4c0f634581e8686 319 Gene3D G3DSA:3.30.2350.10 95 318 7.8E-72 T 28-03-2018 MKLM6_RS19580 e38f7570143a642ac4c0f634581e8686 319 Gene3D G3DSA:3.10.290.10 11 83 2.4E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MKLM6_RS19580 e38f7570143a642ac4c0f634581e8686 319 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 21 314 1.9E-83 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS19580 e38f7570143a642ac4c0f634581e8686 319 Pfam PF01479 S4 domain 24 70 3.0E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MKLM6_RS19580 e38f7570143a642ac4c0f634581e8686 319 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 143 157 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS19580 e38f7570143a642ac4c0f634581e8686 319 SMART SM00363 24 85 6.1E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MKLM6_RS19580 e38f7570143a642ac4c0f634581e8686 319 SUPERFAMILY SSF55174 23 74 5.89E-9 T 28-03-2018 MKLM6_RS19580 e38f7570143a642ac4c0f634581e8686 319 Pfam PF00849 RNA pseudouridylate synthase 105 252 2.0E-29 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS14445 9ab5e789df45d12f18073cb58bbb54e4 1156 SUPERFAMILY SSF81901 251 486 1.54E-20 T 28-03-2018 MKLM6_RS14445 9ab5e789df45d12f18073cb58bbb54e4 1156 SUPERFAMILY SSF48452 444 577 3.96E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS14445 9ab5e789df45d12f18073cb58bbb54e4 1156 SMART SM00028 313 346 30.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS14445 9ab5e789df45d12f18073cb58bbb54e4 1156 SMART SM00028 279 312 490.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS14445 9ab5e789df45d12f18073cb58bbb54e4 1156 SMART SM00028 449 482 46.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS14445 9ab5e789df45d12f18073cb58bbb54e4 1156 SMART SM00028 347 380 2.2 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS14445 9ab5e789df45d12f18073cb58bbb54e4 1156 SMART SM00028 381 414 430.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS14445 9ab5e789df45d12f18073cb58bbb54e4 1156 SMART SM00028 415 448 130.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS14445 9ab5e789df45d12f18073cb58bbb54e4 1156 SMART SM00028 245 278 41.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS14445 9ab5e789df45d12f18073cb58bbb54e4 1156 Gene3D G3DSA:2.40.170.20 639 1154 1.4E-20 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS14445 9ab5e789df45d12f18073cb58bbb54e4 1156 Gene3D G3DSA:1.25.40.10 172 314 4.1E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS14445 9ab5e789df45d12f18073cb58bbb54e4 1156 SUPERFAMILY SSF56935 906 1001 1.22E-23 T 28-03-2018 MKLM6_RS14445 9ab5e789df45d12f18073cb58bbb54e4 1156 SUPERFAMILY SSF56935 634 879 1.22E-23 T 28-03-2018 MKLM6_RS14445 9ab5e789df45d12f18073cb58bbb54e4 1156 SUPERFAMILY SSF56935 1041 1153 1.22E-23 T 28-03-2018 MKLM6_RS14445 9ab5e789df45d12f18073cb58bbb54e4 1156 Pfam PF04773 FecR protein 65 157 4.0E-11 T 28-03-2018 IPR006860 FecR protein MKLM6_RS14445 9ab5e789df45d12f18073cb58bbb54e4 1156 Gene3D G3DSA:1.25.40.10 472 578 1.0E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS14445 9ab5e789df45d12f18073cb58bbb54e4 1156 Gene3D G3DSA:1.25.40.10 392 471 1.9E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS14445 9ab5e789df45d12f18073cb58bbb54e4 1156 Pfam PF00593 TonB dependent receptor 676 1153 2.7E-4 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS14445 9ab5e789df45d12f18073cb58bbb54e4 1156 Gene3D G3DSA:1.25.40.10 315 391 8.3E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 Pfam PF00563 EAL domain 1248 1483 1.3E-77 T 28-03-2018 IPR001633 EAL domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 Gene3D G3DSA:3.30.450.20 948 1070 2.0E-24 T 28-03-2018 MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 Gene3D G3DSA:3.30.450.20 261 388 6.8E-25 T 28-03-2018 MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 Gene3D G3DSA:3.30.450.20 389 503 4.0E-33 T 28-03-2018 MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SUPERFAMILY SSF55781 622 803 2.4E-26 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SUPERFAMILY SSF55785 830 941 9.95E-20 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 Pfam PF00072 Response regulator receiver domain 12 122 2.7E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SUPERFAMILY SSF55785 497 626 1.53E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 Pfam PF00990 Diguanylate cyclase, GGDEF domain 1073 1227 9.7E-50 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 Pfam PF13426 PAS domain 959 1061 3.2E-13 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SUPERFAMILY SSF55785 953 1060 6.63E-26 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SUPERFAMILY SSF52172 10 133 1.99E-33 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SMART SM00065 657 811 1.9E-10 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 Gene3D G3DSA:3.30.450.40 637 810 3.6E-28 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 Pfam PF00989 PAS fold 265 371 3.3E-14 T 28-03-2018 IPR013767 PAS fold GO:0006355 MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 Pfam PF00989 PAS fold 142 256 2.6E-10 T 28-03-2018 IPR013767 PAS fold GO:0006355 MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 Pfam PF13185 GAF domain 656 802 6.3E-20 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SUPERFAMILY SSF55785 128 256 1.24E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 Pfam PF08448 PAS fold 398 502 3.9E-12 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SUPERFAMILY SSF55785 275 387 6.94E-26 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SUPERFAMILY SSF55073 1078 1233 1.7E-50 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SMART SM00052 1242 1488 6.3E-130 T 28-03-2018 IPR001633 EAL domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SUPERFAMILY SSF55785 378 498 3.67E-27 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 1070 1230 1.1E-42 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SMART SM00091 140 209 1.8E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SMART SM00091 822 890 0.67 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SMART SM00091 948 1014 2.4E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SMART SM00091 512 580 7.5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SMART SM00091 392 458 4.6E-14 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SMART SM00091 264 330 1.1E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 Gene3D G3DSA:3.40.50.2300 1 132 1.2E-29 T 28-03-2018 MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 945 1068 1.0E-23 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 389 507 6.9E-24 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 138 265 2.4E-11 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 818 947 1.1E-11 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 261 387 1.6E-24 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 558 634 3.8E-6 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SMART SM00267 1062 1232 1.1E-66 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 Gene3D G3DSA:3.30.450.20 811 947 1.1E-29 T 28-03-2018 MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 Gene3D G3DSA:3.30.450.20 504 636 1.8E-27 T 28-03-2018 MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 Pfam PF08447 PAS fold 535 622 6.8E-15 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 Pfam PF08447 PAS fold 847 934 2.7E-20 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 Gene3D G3DSA:3.20.20.450 1236 1500 9.5E-109 T 28-03-2018 IPR001633 EAL domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SMART SM00448 10 122 1.3E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SMART SM00086 897 940 1.4E-6 T 28-03-2018 IPR001610 PAC motif MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SMART SM00086 586 628 3.0E-7 T 28-03-2018 IPR001610 PAC motif MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SMART SM00086 1020 1062 0.031 T 28-03-2018 IPR001610 PAC motif MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SMART SM00086 340 380 0.072 T 28-03-2018 IPR001610 PAC motif MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SMART SM00086 463 500 0.04 T 28-03-2018 IPR001610 PAC motif MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SMART SM00086 217 259 0.63 T 28-03-2018 IPR001610 PAC motif MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 Gene3D G3DSA:3.30.70.270 1071 1235 5.9E-62 T 28-03-2018 MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 SUPERFAMILY SSF141868 1247 1497 5.75E-97 T 28-03-2018 IPR001633 EAL domain MKLM6_RS07890 f21f9f8789821d116a2957fd5100b5d8 1508 Gene3D G3DSA:3.30.450.20 133 260 7.2E-22 T 28-03-2018 MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 Gene3D G3DSA:3.40.228.10 405 498 1.2E-18 T 28-03-2018 MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 Gene3D G3DSA:3.30.70.20 175 219 7.7E-9 T 28-03-2018 MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 Gene3D G3DSA:3.40.50.740 301 404 5.1E-24 T 28-03-2018 MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 PIRSF PIRSF036643 20 954 0.0 T 28-03-2018 MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 SMART SM00926 242 296 1.1E-15 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 Gene3D G3DSA:3.40.50.740 504 782 1.2E-78 T 28-03-2018 MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 SUPERFAMILY SSF54292 25 97 2.28E-17 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 Gene3D G3DSA:2.40.40.20 795 945 1.1E-34 T 28-03-2018 MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 SUPERFAMILY SSF53706 244 766 3.27E-192 T 28-03-2018 MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 Pfam PF00384 Molybdopterin oxidoreductase 299 717 7.9E-71 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 215 226 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 24 100 3.7E-20 T 28-03-2018 MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 Gene3D G3DSA:3.30.70.20 125 174 0.0053 T 28-03-2018 MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 852 879 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 SMART SM00929 106 146 4.2E-18 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 SUPERFAMILY SSF50692 781 924 3.16E-41 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 Gene3D G3DSA:3.10.20.30 20 124 9.5E-15 T 28-03-2018 IPR012675 Beta-grasp domain MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 106 145 4.1E-16 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 246 296 5.6E-15 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 Gene3D G3DSA:3.30.70.20 220 246 0.45 T 28-03-2018 MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 SUPERFAMILY SSF54862 98 237 1.0E-37 T 28-03-2018 MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 172 183 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 Pfam PF01568 Molydopterin dinucleotide binding domain 814 918 8.2E-26 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 247 265 - T 28-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 247 922 3.4E-283 T 28-03-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 MKLM6_RS16745 7e3c6809f474141629fb4a9d72e41d4f 955 Gene3D G3DSA:2.20.25.90 247 300 4.7E-17 T 28-03-2018 MKLM6_RS13285 cecc0679855de6d278f11ca568699ac0 406 TIGRFAM TIGR01941 nqrF: NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit 4 406 3.5E-208 T 28-03-2018 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 MKLM6_RS13285 cecc0679855de6d278f11ca568699ac0 406 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 372 380 1.3E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MKLM6_RS13285 cecc0679855de6d278f11ca568699ac0 406 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 275 294 1.3E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MKLM6_RS13285 cecc0679855de6d278f11ca568699ac0 406 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 208 215 1.3E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MKLM6_RS13285 cecc0679855de6d278f11ca568699ac0 406 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 241 250 1.3E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MKLM6_RS13285 cecc0679855de6d278f11ca568699ac0 406 SUPERFAMILY SSF54292 38 121 9.18E-22 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MKLM6_RS13285 cecc0679855de6d278f11ca568699ac0 406 SUPERFAMILY SSF63380 104 271 5.33E-37 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MKLM6_RS13285 cecc0679855de6d278f11ca568699ac0 406 PIRSF PIRSF000044 1 406 1.6E-217 T 28-03-2018 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 MKLM6_RS13285 cecc0679855de6d278f11ca568699ac0 406 Gene3D G3DSA:2.40.30.10 136 255 4.2E-33 T 28-03-2018 MKLM6_RS13285 cecc0679855de6d278f11ca568699ac0 406 Gene3D G3DSA:3.10.20.30 32 135 3.0E-21 T 28-03-2018 IPR012675 Beta-grasp domain MKLM6_RS13285 cecc0679855de6d278f11ca568699ac0 406 Hamap MF_00430 Na(+)-translocating NADH-quinone reductase subunit F [nqrF]. 2 406 60.851 T 28-03-2018 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 MKLM6_RS13285 cecc0679855de6d278f11ca568699ac0 406 Pfam PF00175 Oxidoreductase NAD-binding domain 276 384 1.7E-16 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MKLM6_RS13285 cecc0679855de6d278f11ca568699ac0 406 Pfam PF00970 Oxidoreductase FAD-binding domain 204 265 8.2E-6 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 MKLM6_RS13285 cecc0679855de6d278f11ca568699ac0 406 SUPERFAMILY SSF52343 254 402 2.88E-37 T 28-03-2018 MKLM6_RS13285 cecc0679855de6d278f11ca568699ac0 406 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 42 114 7.4E-11 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MKLM6_RS13285 cecc0679855de6d278f11ca568699ac0 406 Gene3D G3DSA:3.40.50.80 256 401 1.0E-29 T 28-03-2018 MKLM6_RS15485 e8a6965666cb8de5f863d5ffc251653d 291 Gene3D G3DSA:1.10.10.10 1 76 4.3E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS15485 e8a6965666cb8de5f863d5ffc251653d 291 Pfam PF03466 LysR substrate binding domain 88 275 3.7E-16 T 28-03-2018 IPR005119 LysR, substrate-binding MKLM6_RS15485 e8a6965666cb8de5f863d5ffc251653d 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS15485 e8a6965666cb8de5f863d5ffc251653d 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS15485 e8a6965666cb8de5f863d5ffc251653d 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS15485 e8a6965666cb8de5f863d5ffc251653d 291 SUPERFAMILY SSF53850 89 280 1.35E-20 T 28-03-2018 MKLM6_RS15485 e8a6965666cb8de5f863d5ffc251653d 291 Gene3D G3DSA:3.40.190.10 77 287 1.1E-14 T 28-03-2018 MKLM6_RS15485 e8a6965666cb8de5f863d5ffc251653d 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.3E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS15485 e8a6965666cb8de5f863d5ffc251653d 291 SUPERFAMILY SSF46785 1 109 2.73E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS12825 d7e43836d1922b5249d04c2f0f05e3a6 203 Pfam PF02581 Thiamine monophosphate synthase 8 186 7.3E-54 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MKLM6_RS12825 d7e43836d1922b5249d04c2f0f05e3a6 203 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 6 203 24.826 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MKLM6_RS12825 d7e43836d1922b5249d04c2f0f05e3a6 203 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 8 194 1.4E-54 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MKLM6_RS12825 d7e43836d1922b5249d04c2f0f05e3a6 203 Gene3D G3DSA:3.20.20.70 2 203 1.6E-41 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS12825 d7e43836d1922b5249d04c2f0f05e3a6 203 SUPERFAMILY SSF51391 5 201 2.09E-56 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MKLM6_RS15200 eaef02f896129e823e4a19799973ca27 462 TIGRFAM TIGR03013 EpsB_2: sugar transferase, PEP-CTERM system associated 19 462 1.2E-172 T 28-03-2018 IPR017464 Sugar transferase, PEP-CTERM system associated MKLM6_RS15200 eaef02f896129e823e4a19799973ca27 462 Pfam PF02397 Bacterial sugar transferase 272 456 4.0E-67 T 28-03-2018 IPR003362 Bacterial sugar transferase MKLM6_RS15200 eaef02f896129e823e4a19799973ca27 462 Gene3D G3DSA:3.40.50.720 137 253 1.4E-5 T 28-03-2018 MKLM6_RS15200 eaef02f896129e823e4a19799973ca27 462 Pfam PF13727 CoA-binding domain 65 210 2.4E-8 T 28-03-2018 MKLM6_RS15200 eaef02f896129e823e4a19799973ca27 462 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 21 462 6.3E-123 T 28-03-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase MKLM6_RS03465 654fa4aa302ba4dfb90da5caf14a44df 915 SUPERFAMILY SSF141868 651 899 3.27E-93 T 28-03-2018 IPR001633 EAL domain MKLM6_RS03465 654fa4aa302ba4dfb90da5caf14a44df 915 SMART SM00091 162 228 1.1E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03465 654fa4aa302ba4dfb90da5caf14a44df 915 Gene3D G3DSA:3.30.450.40 285 463 2.6E-27 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS03465 654fa4aa302ba4dfb90da5caf14a44df 915 Pfam PF00990 Diguanylate cyclase, GGDEF domain 470 631 1.0E-45 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS03465 654fa4aa302ba4dfb90da5caf14a44df 915 Gene3D G3DSA:3.20.20.450 638 906 3.7E-105 T 28-03-2018 IPR001633 EAL domain MKLM6_RS03465 654fa4aa302ba4dfb90da5caf14a44df 915 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 466 634 1.4E-39 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS03465 654fa4aa302ba4dfb90da5caf14a44df 915 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 162 283 8.5E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03465 654fa4aa302ba4dfb90da5caf14a44df 915 Pfam PF00563 EAL domain 652 887 1.0E-72 T 28-03-2018 IPR001633 EAL domain MKLM6_RS03465 654fa4aa302ba4dfb90da5caf14a44df 915 Pfam PF00072 Response regulator receiver domain 8 120 1.5E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS03465 654fa4aa302ba4dfb90da5caf14a44df 915 Pfam PF08448 PAS fold 168 279 4.6E-21 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS03465 654fa4aa302ba4dfb90da5caf14a44df 915 SMART SM00052 646 892 7.1E-119 T 28-03-2018 IPR001633 EAL domain MKLM6_RS03465 654fa4aa302ba4dfb90da5caf14a44df 915 SMART SM00448 6 119 2.9E-45 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS03465 654fa4aa302ba4dfb90da5caf14a44df 915 SUPERFAMILY SSF55785 167 279 1.92E-21 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03465 654fa4aa302ba4dfb90da5caf14a44df 915 SUPERFAMILY SSF52172 4 178 3.7E-43 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS03465 654fa4aa302ba4dfb90da5caf14a44df 915 Gene3D G3DSA:3.30.450.20 161 284 1.0E-23 T 28-03-2018 MKLM6_RS03465 654fa4aa302ba4dfb90da5caf14a44df 915 SUPERFAMILY SSF55781 309 463 1.53E-19 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS03465 654fa4aa302ba4dfb90da5caf14a44df 915 Pfam PF13185 GAF domain 307 451 1.7E-18 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS03465 654fa4aa302ba4dfb90da5caf14a44df 915 SUPERFAMILY SSF55073 475 638 1.41E-45 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS03465 654fa4aa302ba4dfb90da5caf14a44df 915 SMART SM00267 459 636 2.3E-60 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS03465 654fa4aa302ba4dfb90da5caf14a44df 915 Gene3D G3DSA:3.30.70.270 464 637 2.4E-58 T 28-03-2018 MKLM6_RS03465 654fa4aa302ba4dfb90da5caf14a44df 915 Gene3D G3DSA:3.40.50.2300 1 160 3.6E-42 T 28-03-2018 MKLM6_RS06430 0de59a1a031c5de045db915177abf0d3 282 Gene3D G3DSA:1.10.10.10 216 275 1.0E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS06430 0de59a1a031c5de045db915177abf0d3 282 Pfam PF13509 S1 domain 4 63 3.1E-9 T 28-03-2018 MKLM6_RS06430 0de59a1a031c5de045db915177abf0d3 282 PIRSF PIRSF012524 1 277 2.7E-63 T 28-03-2018 IPR014464 Conserved virulence factor B MKLM6_RS06430 0de59a1a031c5de045db915177abf0d3 282 Gene3D G3DSA:2.40.50.140 56 206 2.4E-14 T 28-03-2018 MKLM6_RS10745 432ea2f145b4f5f42374280235c6b7a7 143 Gene3D G3DSA:3.40.630.30 1 139 1.9E-29 T 28-03-2018 MKLM6_RS10745 432ea2f145b4f5f42374280235c6b7a7 143 SUPERFAMILY SSF55729 1 130 1.3E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS10745 432ea2f145b4f5f42374280235c6b7a7 143 Pfam PF00583 Acetyltransferase (GNAT) family 25 124 2.8E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 MKLM6_RS03315 1b9bc572c7d95910e291336ecfacc037 169 Pfam PF00226 DnaJ domain 107 166 1.2E-9 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS03315 1b9bc572c7d95910e291336ecfacc037 169 Gene3D G3DSA:1.10.287.110 23 168 3.9E-13 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS03315 1b9bc572c7d95910e291336ecfacc037 169 PRINTS PR00625 DnaJ domain signature 126 141 1.9E-7 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS03315 1b9bc572c7d95910e291336ecfacc037 169 PRINTS PR00625 DnaJ domain signature 148 168 1.9E-7 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS03315 1b9bc572c7d95910e291336ecfacc037 169 PRINTS PR00625 DnaJ domain signature 108 126 1.9E-7 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS03315 1b9bc572c7d95910e291336ecfacc037 169 SMART SM00271 105 168 8.8E-9 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS03315 1b9bc572c7d95910e291336ecfacc037 169 SUPERFAMILY SSF46565 106 166 7.46E-14 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS00670 70d8f2d61af7ba20236e9dc41a7776fa 632 SMART SM00267 465 632 1.5E-51 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS00670 70d8f2d61af7ba20236e9dc41a7776fa 632 SUPERFAMILY SSF55785 365 474 4.19E-21 T 28-03-2018 IPR000014 PAS domain MKLM6_RS00670 70d8f2d61af7ba20236e9dc41a7776fa 632 Gene3D G3DSA:3.30.70.270 470 631 1.7E-55 T 28-03-2018 MKLM6_RS00670 70d8f2d61af7ba20236e9dc41a7776fa 632 Pfam PF08448 PAS fold 357 466 1.5E-12 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS00670 70d8f2d61af7ba20236e9dc41a7776fa 632 Gene3D G3DSA:3.30.450.20 347 469 1.3E-25 T 28-03-2018 MKLM6_RS00670 70d8f2d61af7ba20236e9dc41a7776fa 632 Gene3D G3DSA:3.40.190.10 20 309 1.7E-33 T 28-03-2018 MKLM6_RS00670 70d8f2d61af7ba20236e9dc41a7776fa 632 Pfam PF09084 NMT1/THI5 like 34 239 2.6E-43 T 28-03-2018 IPR015168 SsuA/THI5-like MKLM6_RS00670 70d8f2d61af7ba20236e9dc41a7776fa 632 Pfam PF00990 Diguanylate cyclase, GGDEF domain 476 628 5.4E-46 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS00670 70d8f2d61af7ba20236e9dc41a7776fa 632 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 472 628 2.4E-41 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS00670 70d8f2d61af7ba20236e9dc41a7776fa 632 SUPERFAMILY SSF55073 481 629 7.53E-45 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS00670 70d8f2d61af7ba20236e9dc41a7776fa 632 SMART SM00091 351 417 5.6E-6 T 28-03-2018 IPR000014 PAS domain MKLM6_RS00670 70d8f2d61af7ba20236e9dc41a7776fa 632 SMART SM00086 423 465 3.3E-7 T 28-03-2018 IPR001610 PAC motif MKLM6_RS00670 70d8f2d61af7ba20236e9dc41a7776fa 632 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 350 472 4.1E-22 T 28-03-2018 IPR000014 PAS domain MKLM6_RS00670 70d8f2d61af7ba20236e9dc41a7776fa 632 SUPERFAMILY SSF53850 21 248 1.72E-24 T 28-03-2018 MKLM6_RS07045 8502c767122c929160b11d9adbb9d750 323 SUPERFAMILY SSF51735 2 317 9.89E-77 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS07045 8502c767122c929160b11d9adbb9d750 323 Gene3D G3DSA:3.90.25.10 161 323 3.0E-47 T 28-03-2018 MKLM6_RS07045 8502c767122c929160b11d9adbb9d750 323 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 229 1.0E-75 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MKLM6_RS07045 8502c767122c929160b11d9adbb9d750 323 Gene3D G3DSA:3.40.50.720 1 160 3.1E-12 T 28-03-2018 MKLM6_RS07045 8502c767122c929160b11d9adbb9d750 323 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 4 315 49.85 T 28-03-2018 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00010+1.1.1.27|KEGG: 00051+1.1.1.271|KEGG: 00270+1.1.1.27|KEGG: 00520+1.1.1.271|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-66|MetaCyc: PWY-6901|Reactome: R-HSA-6787639 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 SMART SM00433 34 625 1.3E-210 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 559 621 2.0E-24 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 Pfam PF00204 DNA gyrase B 218 385 4.3E-39 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 Gene3D G3DSA:3.30.565.10 17 216 1.7E-64 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 2 629 46.093 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 SUPERFAMILY SSF55874 5 215 5.37E-67 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 SUPERFAMILY SSF54211 217 382 1.5E-43 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 ProSitePatterns PS00177 DNA topoisomerase II signature. 417 425 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 28 171 3.4E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 PRINTS PR00418 DNA topoisomerase II family signature 31 46 2.4E-60 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 PRINTS PR00418 DNA topoisomerase II family signature 66 79 2.4E-60 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 PRINTS PR00418 DNA topoisomerase II family signature 109 123 2.4E-60 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 PRINTS PR00418 DNA topoisomerase II family signature 498 515 2.4E-60 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 PRINTS PR00418 DNA topoisomerase II family signature 563 579 2.4E-60 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 PRINTS PR00418 DNA topoisomerase II family signature 415 429 2.4E-60 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 PRINTS PR00418 DNA topoisomerase II family signature 267 280 2.4E-60 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 PRINTS PR00418 DNA topoisomerase II family signature 518 530 2.4E-60 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 PRINTS PR00418 DNA topoisomerase II family signature 480 496 2.4E-60 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 SMART SM00387 27 173 8.8E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 Pfam PF01751 Toprim domain 414 522 1.6E-13 T 28-03-2018 IPR006171 TOPRIM domain MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 TIGRFAM TIGR01055 parE_Gneg: DNA topoisomerase IV, B subunit 2 625 2.9E-295 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 SUPERFAMILY SSF56719 389 622 2.88E-77 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 PRINTS PR01098 Topoisomerase IV subunit B signature 238 261 1.6E-97 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 PRINTS PR01098 Topoisomerase IV subunit B signature 470 482 1.6E-97 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 PRINTS PR01098 Topoisomerase IV subunit B signature 135 149 1.6E-97 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 PRINTS PR01098 Topoisomerase IV subunit B signature 363 388 1.6E-97 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 PRINTS PR01098 Topoisomerase IV subunit B signature 174 191 1.6E-97 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 PRINTS PR01098 Topoisomerase IV subunit B signature 312 327 1.6E-97 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 PRINTS PR01098 Topoisomerase IV subunit B signature 449 470 1.6E-97 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 PRINTS PR01098 Topoisomerase IV subunit B signature 295 311 1.6E-97 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 PRINTS PR01098 Topoisomerase IV subunit B signature 149 164 1.6E-97 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 PRINTS PR01098 Topoisomerase IV subunit B signature 339 362 1.6E-97 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 PRINTS PR01098 Topoisomerase IV subunit B signature 538 560 1.6E-97 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 PRINTS PR01098 Topoisomerase IV subunit B signature 26 39 1.6E-97 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 PRINTS PR01098 Topoisomerase IV subunit B signature 192 213 1.6E-97 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 PRINTS PR01098 Topoisomerase IV subunit B signature 504 520 1.6E-97 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 Gene3D G3DSA:3.30.230.10 217 391 9.3E-41 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MKLM6_RS06420 6c850dad43f87f75e9de42366da8a698 630 Gene3D G3DSA:3.40.50.670 397 628 1.1E-77 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS10995 95ce2f9d3f4e8cc7578bcffdf4d4a1eb 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 1.5E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS10995 95ce2f9d3f4e8cc7578bcffdf4d4a1eb 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 1.5E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS10995 95ce2f9d3f4e8cc7578bcffdf4d4a1eb 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 1.5E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS10995 95ce2f9d3f4e8cc7578bcffdf4d4a1eb 230 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MKLM6_RS10995 95ce2f9d3f4e8cc7578bcffdf4d4a1eb 230 Gene3D G3DSA:3.40.50.720 4 221 2.9E-51 T 28-03-2018 MKLM6_RS10995 95ce2f9d3f4e8cc7578bcffdf4d4a1eb 230 Pfam PF00106 short chain dehydrogenase 6 190 1.1E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS10995 95ce2f9d3f4e8cc7578bcffdf4d4a1eb 230 SUPERFAMILY SSF51735 5 229 4.3E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS10995 95ce2f9d3f4e8cc7578bcffdf4d4a1eb 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 5.9E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS10995 95ce2f9d3f4e8cc7578bcffdf4d4a1eb 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 5.9E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS10995 95ce2f9d3f4e8cc7578bcffdf4d4a1eb 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 5.9E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS10995 95ce2f9d3f4e8cc7578bcffdf4d4a1eb 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 5.9E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS10995 95ce2f9d3f4e8cc7578bcffdf4d4a1eb 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 5.9E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS04630 9a021d31b345fbd593daf4ced4795636 228 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 11 217 5.0E-68 T 28-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 MKLM6_RS04630 9a021d31b345fbd593daf4ced4795636 228 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 28 218 3.9E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MKLM6_RS04630 9a021d31b345fbd593daf4ced4795636 228 Gene3D G3DSA:1.10.3720.10 6 220 4.9E-33 T 28-03-2018 MKLM6_RS04630 9a021d31b345fbd593daf4ced4795636 228 SUPERFAMILY SSF161098 7 215 1.57E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MKLM6_RS16650 c308890f7b600ea83e56e23658587945 803 Pfam PF02687 FtsX-like permease family 288 378 1.0E-5 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MKLM6_RS16650 c308890f7b600ea83e56e23658587945 803 Pfam PF02687 FtsX-like permease family 703 795 2.6E-12 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MKLM6_RS02750 f1f44038026cc6ed89b38621d18fd303 471 SUPERFAMILY SSF52540 253 445 4.46E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS02750 f1f44038026cc6ed89b38621d18fd303 471 SMART SM00962 256 448 6.1E-50 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MKLM6_RS02750 f1f44038026cc6ed89b38621d18fd303 471 Pfam PF00448 SRP54-type protein, GTPase domain 259 446 2.1E-38 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MKLM6_RS02750 f1f44038026cc6ed89b38621d18fd303 471 SMART SM00382 255 421 4.4E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS02750 f1f44038026cc6ed89b38621d18fd303 471 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 1 344 4.7E-78 T 28-03-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 MKLM6_RS02750 f1f44038026cc6ed89b38621d18fd303 471 Gene3D G3DSA:3.40.50.300 253 449 1.9E-21 T 28-03-2018 MKLM6_RS04050 b789b194aaf49438b83af213a93606f9 528 SUPERFAMILY SSF88713 4 413 1.1E-108 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MKLM6_RS04050 b789b194aaf49438b83af213a93606f9 528 Pfam PF09210 Domain of unknown function (DUF1957) 425 526 1.0E-33 T 28-03-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 MKLM6_RS04050 b789b194aaf49438b83af213a93606f9 528 Gene3D G3DSA:3.20.110.10 1 413 2.3E-103 T 28-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain MKLM6_RS04050 b789b194aaf49438b83af213a93606f9 528 Pfam PF03065 Glycosyl hydrolase family 57 7 362 8.9E-45 T 28-03-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 MKLM6_RS04050 b789b194aaf49438b83af213a93606f9 528 Gene3D G3DSA:1.20.1430.10 415 528 4.9E-38 T 28-03-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 MKLM6_RS04050 b789b194aaf49438b83af213a93606f9 528 SUPERFAMILY SSF88688 417 527 9.48E-37 T 28-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain MKLM6_RS12210 9926247381d17e1380fd058e9ee0e252 674 SMART SM00448 13 126 1.1E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS12210 9926247381d17e1380fd058e9ee0e252 674 Pfam PF00072 Response regulator receiver domain 15 126 2.2E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS12210 9926247381d17e1380fd058e9ee0e252 674 SUPERFAMILY SSF55073 275 419 9.42E-23 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS12210 9926247381d17e1380fd058e9ee0e252 674 Pfam PF00990 Diguanylate cyclase, GGDEF domain 272 409 4.7E-20 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS12210 9926247381d17e1380fd058e9ee0e252 674 SUPERFAMILY SSF52172 8 141 5.55E-35 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS12210 9926247381d17e1380fd058e9ee0e252 674 Pfam PF00563 EAL domain 436 663 3.9E-53 T 28-03-2018 IPR001633 EAL domain MKLM6_RS12210 9926247381d17e1380fd058e9ee0e252 674 Pfam PF13426 PAS domain 162 258 7.1E-11 T 28-03-2018 IPR000014 PAS domain MKLM6_RS12210 9926247381d17e1380fd058e9ee0e252 674 SMART SM00267 260 418 8.4E-14 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS12210 9926247381d17e1380fd058e9ee0e252 674 Gene3D G3DSA:3.20.20.450 415 668 2.3E-65 T 28-03-2018 IPR001633 EAL domain MKLM6_RS12210 9926247381d17e1380fd058e9ee0e252 674 Gene3D G3DSA:3.40.50.2300 1 148 2.9E-30 T 28-03-2018 MKLM6_RS12210 9926247381d17e1380fd058e9ee0e252 674 SUPERFAMILY SSF141868 436 666 9.15E-61 T 28-03-2018 IPR001633 EAL domain MKLM6_RS12210 9926247381d17e1380fd058e9ee0e252 674 SUPERFAMILY SSF55785 156 256 6.63E-24 T 28-03-2018 IPR000014 PAS domain MKLM6_RS12210 9926247381d17e1380fd058e9ee0e252 674 Gene3D G3DSA:3.30.70.270 287 412 2.8E-22 T 28-03-2018 MKLM6_RS12210 9926247381d17e1380fd058e9ee0e252 674 Gene3D G3DSA:3.30.450.20 149 286 1.9E-28 T 28-03-2018 MKLM6_RS12210 9926247381d17e1380fd058e9ee0e252 674 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 145 265 2.0E-11 T 28-03-2018 IPR000014 PAS domain MKLM6_RS12210 9926247381d17e1380fd058e9ee0e252 674 SMART SM00052 430 668 2.2E-55 T 28-03-2018 IPR001633 EAL domain MKLM6_RS12210 9926247381d17e1380fd058e9ee0e252 674 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 268 401 7.5E-15 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS12090 a138b9cc90fdefc8bc0958ef8ac257fd 266 Pfam PF00231 ATP synthase 5 259 1.8E-23 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12090 a138b9cc90fdefc8bc0958ef8ac257fd 266 SUPERFAMILY SSF52943 5 259 2.35E-26 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12090 a138b9cc90fdefc8bc0958ef8ac257fd 266 Gene3D G3DSA:1.10.287.80 5 122 8.6E-10 T 28-03-2018 MKLM6_RS13130 3ce6cad48b3ed22c27fd2a28848c384a 739 SUPERFAMILY SSF48113 28 432 2.06E-147 T 28-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 MKLM6_RS13130 3ce6cad48b3ed22c27fd2a28848c384a 739 Gene3D G3DSA:1.10.420.10 234 401 4.0E-38 T 28-03-2018 MKLM6_RS13130 3ce6cad48b3ed22c27fd2a28848c384a 739 Gene3D G3DSA:1.10.420.10 607 714 2.2E-36 T 28-03-2018 MKLM6_RS13130 3ce6cad48b3ed22c27fd2a28848c384a 739 SUPERFAMILY SSF48113 434 738 4.57E-112 T 28-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 MKLM6_RS13130 3ce6cad48b3ed22c27fd2a28848c384a 739 Hamap MF_01961 Catalase-peroxidase [katG]. 9 739 41.169 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 MKLM6_RS13130 3ce6cad48b3ed22c27fd2a28848c384a 739 Gene3D G3DSA:1.10.520.10 63 215 5.6E-37 T 28-03-2018 MKLM6_RS13130 3ce6cad48b3ed22c27fd2a28848c384a 739 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 260 270 - T 28-03-2018 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 MKLM6_RS13130 3ce6cad48b3ed22c27fd2a28848c384a 739 ProSitePatterns PS00436 Peroxidases active site signature. 97 108 - T 28-03-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 MKLM6_RS13130 3ce6cad48b3ed22c27fd2a28848c384a 739 Gene3D G3DSA:1.10.520.10 445 606 2.3E-41 T 28-03-2018 MKLM6_RS13130 3ce6cad48b3ed22c27fd2a28848c384a 739 Pfam PF00141 Peroxidase 91 399 6.9E-50 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MKLM6_RS13130 3ce6cad48b3ed22c27fd2a28848c384a 739 Pfam PF00141 Peroxidase 407 713 5.8E-37 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MKLM6_RS13130 3ce6cad48b3ed22c27fd2a28848c384a 739 PRINTS PR00458 Haem peroxidase superfamily signature 157 174 2.3E-17 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MKLM6_RS13130 3ce6cad48b3ed22c27fd2a28848c384a 739 PRINTS PR00458 Haem peroxidase superfamily signature 175 187 2.3E-17 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MKLM6_RS13130 3ce6cad48b3ed22c27fd2a28848c384a 739 PRINTS PR00458 Haem peroxidase superfamily signature 97 111 2.3E-17 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MKLM6_RS13130 3ce6cad48b3ed22c27fd2a28848c384a 739 PRINTS PR00458 Haem peroxidase superfamily signature 645 660 2.3E-17 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MKLM6_RS13130 3ce6cad48b3ed22c27fd2a28848c384a 739 PRINTS PR00458 Haem peroxidase superfamily signature 260 275 2.3E-17 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MKLM6_RS13130 3ce6cad48b3ed22c27fd2a28848c384a 739 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 268 291 3.9E-42 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 MKLM6_RS13130 3ce6cad48b3ed22c27fd2a28848c384a 739 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 74 99 3.9E-42 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 MKLM6_RS13130 3ce6cad48b3ed22c27fd2a28848c384a 739 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 33 55 3.9E-42 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 MKLM6_RS13130 3ce6cad48b3ed22c27fd2a28848c384a 739 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 59 72 3.9E-42 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 MKLM6_RS13130 3ce6cad48b3ed22c27fd2a28848c384a 739 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 484 510 3.9E-42 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 MKLM6_RS13130 3ce6cad48b3ed22c27fd2a28848c384a 739 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 31 738 0.0 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 MKLM6_RS07005 5f6ad72a65f15c92f46edd104a5a97d4 447 SMART SM00878 336 441 2.8E-64 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MKLM6_RS07005 5f6ad72a65f15c92f46edd104a5a97d4 447 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 446 3.3E-228 T 28-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 MKLM6_RS07005 5f6ad72a65f15c92f46edd104a5a97d4 447 Gene3D G3DSA:3.30.470.20 211 444 7.8E-99 T 28-03-2018 MKLM6_RS07005 5f6ad72a65f15c92f46edd104a5a97d4 447 SUPERFAMILY SSF56059 93 345 5.83E-68 T 28-03-2018 MKLM6_RS07005 5f6ad72a65f15c92f46edd104a5a97d4 447 Gene3D G3DSA:3.30.1490.20 124 210 1.7E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MKLM6_RS07005 5f6ad72a65f15c92f46edd104a5a97d4 447 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MKLM6_RS07005 5f6ad72a65f15c92f46edd104a5a97d4 447 Gene3D G3DSA:3.40.50.20 1 123 3.8E-53 T 28-03-2018 MKLM6_RS07005 5f6ad72a65f15c92f46edd104a5a97d4 447 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 1.4E-38 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MKLM6_RS07005 5f6ad72a65f15c92f46edd104a5a97d4 447 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MKLM6_RS07005 5f6ad72a65f15c92f46edd104a5a97d4 447 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 2.0E-45 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MKLM6_RS07005 5f6ad72a65f15c92f46edd104a5a97d4 447 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 1.2E-83 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MKLM6_RS07005 5f6ad72a65f15c92f46edd104a5a97d4 447 SUPERFAMILY SSF51246 332 444 1.26E-42 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MKLM6_RS07005 5f6ad72a65f15c92f46edd104a5a97d4 447 SUPERFAMILY SSF52440 1 113 2.66E-48 T 28-03-2018 IPR016185 Pre-ATP-grasp domain MKLM6_RS15330 7e5c469b561cbe11fd079e94bb6c93e0 357 Gene3D G3DSA:3.40.50.2000 170 338 6.1E-41 T 28-03-2018 MKLM6_RS15330 7e5c469b561cbe11fd079e94bb6c93e0 357 Gene3D G3DSA:3.40.50.2000 1 169 2.1E-6 T 28-03-2018 MKLM6_RS15330 7e5c469b561cbe11fd079e94bb6c93e0 357 Pfam PF00534 Glycosyl transferases group 1 170 330 9.1E-37 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 MKLM6_RS15330 7e5c469b561cbe11fd079e94bb6c93e0 357 SUPERFAMILY SSF53756 8 354 8.98E-67 T 28-03-2018 MKLM6_RS00305 76bf743783507748640ee65800252873 843 Gene3D G3DSA:1.20.120.330 553 769 3.5E-5 T 28-03-2018 MKLM6_RS00305 76bf743783507748640ee65800252873 843 Pfam PF02384 N-6 DNA Methylase 164 488 2.5E-95 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 MKLM6_RS00305 76bf743783507748640ee65800252873 843 Pfam PF12161 HsdM N-terminal domain 8 150 7.3E-29 T 28-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain MKLM6_RS00305 76bf743783507748640ee65800252873 843 Gene3D G3DSA:3.40.50.150 184 487 7.0E-63 T 28-03-2018 MKLM6_RS00305 76bf743783507748640ee65800252873 843 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 210 224 1.3E-20 T 28-03-2018 MKLM6_RS00305 76bf743783507748640ee65800252873 843 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 186 202 1.3E-20 T 28-03-2018 MKLM6_RS00305 76bf743783507748640ee65800252873 843 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 287 299 1.3E-20 T 28-03-2018 MKLM6_RS00305 76bf743783507748640ee65800252873 843 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 333 357 1.3E-20 T 28-03-2018 MKLM6_RS00305 76bf743783507748640ee65800252873 843 SUPERFAMILY SSF53335 7 45 7.36E-130 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS00305 76bf743783507748640ee65800252873 843 SUPERFAMILY SSF53335 79 511 7.36E-130 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS08790 fe4fdab68cdb77a8e67393ea36d075c0 483 Pfam PF14559 Tetratricopeptide repeat 353 417 9.7E-9 T 28-03-2018 MKLM6_RS08790 fe4fdab68cdb77a8e67393ea36d075c0 483 Gene3D G3DSA:3.30.2010.10 54 148 1.9E-18 T 28-03-2018 MKLM6_RS08790 fe4fdab68cdb77a8e67393ea36d075c0 483 Pfam PF01435 Peptidase family M48 69 254 2.1E-32 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MKLM6_RS08790 fe4fdab68cdb77a8e67393ea36d075c0 483 Gene3D G3DSA:1.25.40.10 368 468 1.6E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS08790 fe4fdab68cdb77a8e67393ea36d075c0 483 Hamap MF_00997 Beta-barrel assembly-enhancing protease [bepA]. 1 482 35.035 T 28-03-2018 IPR030873 Beta-barrel assembly-enhancing protease GO:0006508|GO:0008237|GO:0016020|GO:0061077 MKLM6_RS08790 fe4fdab68cdb77a8e67393ea36d075c0 483 Gene3D G3DSA:1.25.40.10 268 367 2.1E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS08790 fe4fdab68cdb77a8e67393ea36d075c0 483 SUPERFAMILY SSF48452 306 453 3.29E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS03810 adc2e949e03855bef343c0069ec1f56e 431 Pfam PF01551 Peptidase family M23 293 389 5.3E-30 T 28-03-2018 IPR016047 Peptidase M23 MKLM6_RS03810 adc2e949e03855bef343c0069ec1f56e 431 Pfam PF04225 Opacity-associated protein A LysM-like domain 70 146 2.3E-8 T 28-03-2018 IPR007340 Opacity-associated protein A MKLM6_RS03810 adc2e949e03855bef343c0069ec1f56e 431 SUPERFAMILY SSF51261 139 390 2.88E-68 T 28-03-2018 IPR011055 Duplicated hybrid motif MKLM6_RS03810 adc2e949e03855bef343c0069ec1f56e 431 Gene3D G3DSA:2.70.70.10 234 431 5.3E-38 T 28-03-2018 MKLM6_RS03810 adc2e949e03855bef343c0069ec1f56e 431 Gene3D G3DSA:3.10.350.10 67 116 5.3E-4 T 28-03-2018 MKLM6_RS01570 ee42d5a525d70eb3899a80a3d5a670d0 1202 Pfam PF02538 Hydantoinase B/oxoprolinase 695 1200 2.5E-201 T 28-03-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403 MKLM6_RS01570 ee42d5a525d70eb3899a80a3d5a670d0 1202 Gene3D G3DSA:3.30.420.40 9 156 1.1E-4 T 28-03-2018 MKLM6_RS01570 ee42d5a525d70eb3899a80a3d5a670d0 1202 Pfam PF01968 Hydantoinase/oxoprolinase 203 496 1.1E-102 T 28-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 MKLM6_RS01570 ee42d5a525d70eb3899a80a3d5a670d0 1202 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 7 182 2.8E-55 T 28-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 MKLM6_RS01570 ee42d5a525d70eb3899a80a3d5a670d0 1202 Gene3D G3DSA:3.30.420.150 260 534 6.2E-4 T 28-03-2018 MKLM6_RS01935 365870398b882188384ed1edffafe5a2 346 SUPERFAMILY SSF52733 2 344 1.57E-112 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MKLM6_RS01935 365870398b882188384ed1edffafe5a2 346 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 16 343 4.0E-131 T 28-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MKLM6_RS01935 365870398b882188384ed1edffafe5a2 346 Pfam PF02277 Phosphoribosyltransferase 9 343 5.4E-126 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MKLM6_RS01935 365870398b882188384ed1edffafe5a2 346 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 10 345 35.209 T 28-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MKLM6_RS01935 365870398b882188384ed1edffafe5a2 346 Gene3D G3DSA:1.10.1610.10 2 68 4.7E-28 T 28-03-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MKLM6_RS01935 365870398b882188384ed1edffafe5a2 346 Gene3D G3DSA:3.40.50.10210 69 326 1.7E-101 T 28-03-2018 MKLM6_RS14965 2037e5b5613b3fc6c88f4a9484d4b82b 469 SMART SM01230 102 379 1.6E-144 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MKLM6_RS14965 2037e5b5613b3fc6c88f4a9484d4b82b 469 Gene3D G3DSA:3.10.20.70 2 104 4.1E-29 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MKLM6_RS14965 2037e5b5613b3fc6c88f4a9484d4b82b 469 Gene3D G3DSA:3.30.590.10 105 456 2.7E-119 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MKLM6_RS14965 2037e5b5613b3fc6c88f4a9484d4b82b 469 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 5 468 2.4E-203 T 28-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MKLM6_RS14965 2037e5b5613b3fc6c88f4a9484d4b82b 469 ProSitePatterns PS00180 Glutamine synthetase signature 1. 50 68 - T 28-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MKLM6_RS14965 2037e5b5613b3fc6c88f4a9484d4b82b 469 Pfam PF00120 Glutamine synthetase, catalytic domain 103 466 1.5E-135 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MKLM6_RS14965 2037e5b5613b3fc6c88f4a9484d4b82b 469 SUPERFAMILY SSF54368 3 100 5.49E-38 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MKLM6_RS14965 2037e5b5613b3fc6c88f4a9484d4b82b 469 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 14 95 7.0E-32 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MKLM6_RS14965 2037e5b5613b3fc6c88f4a9484d4b82b 469 SUPERFAMILY SSF55931 103 468 1.28E-134 T 28-03-2018 MKLM6_RS14965 2037e5b5613b3fc6c88f4a9484d4b82b 469 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 386 398 - T 28-03-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MKLM6_RS14965 2037e5b5613b3fc6c88f4a9484d4b82b 469 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 259 274 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MKLM6_RS21065 b889a6761e567586375af9fce3b0aa20 269 Pfam PF02548 Ketopantoate hydroxymethyltransferase 11 264 3.5E-108 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MKLM6_RS21065 b889a6761e567586375af9fce3b0aa20 269 PIRSF PIRSF000388 4 269 4.2E-101 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MKLM6_RS21065 b889a6761e567586375af9fce3b0aa20 269 SUPERFAMILY SSF51621 11 269 1.45E-100 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MKLM6_RS21065 b889a6761e567586375af9fce3b0aa20 269 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 15 269 3.1E-102 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MKLM6_RS21065 b889a6761e567586375af9fce3b0aa20 269 Gene3D G3DSA:3.20.20.60 2 269 2.6E-79 T 28-03-2018 MKLM6_RS21065 b889a6761e567586375af9fce3b0aa20 269 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 11 269 41.556 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MKLM6_RS21905 065f4dc38c16d548ea48cecb35b87021 203 SMART SM00857 9 150 3.6E-45 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MKLM6_RS21905 065f4dc38c16d548ea48cecb35b87021 203 Pfam PF00239 Resolvase, N terminal domain 10 149 8.1E-34 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MKLM6_RS21905 065f4dc38c16d548ea48cecb35b87021 203 Gene3D G3DSA:1.20.5.40 120 148 1.9E-11 T 28-03-2018 MKLM6_RS21905 065f4dc38c16d548ea48cecb35b87021 203 Gene3D G3DSA:3.40.50.1390 4 119 9.4E-29 T 28-03-2018 MKLM6_RS21905 065f4dc38c16d548ea48cecb35b87021 203 Gene3D G3DSA:1.10.10.60 150 197 3.6E-6 T 28-03-2018 MKLM6_RS21905 065f4dc38c16d548ea48cecb35b87021 203 SUPERFAMILY SSF53041 9 149 5.75E-36 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MKLM6_RS21905 065f4dc38c16d548ea48cecb35b87021 203 ProSitePatterns PS00397 Site-specific recombinases active site. 12 20 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 MKLM6_RS21905 065f4dc38c16d548ea48cecb35b87021 203 ProSitePatterns PS00398 Site-specific recombinases signature 2. 69 81 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 MKLM6_RS22205 163aa8b2943684d14f119ebe2c885599 80 Gene3D G3DSA:2.20.140.10 7 77 2.5E-10 T 28-03-2018 IPR008893 WGR domain MKLM6_RS22205 163aa8b2943684d14f119ebe2c885599 80 Pfam PF05406 WGR domain 4 74 6.5E-17 T 28-03-2018 IPR008893 WGR domain MKLM6_RS22205 163aa8b2943684d14f119ebe2c885599 80 SUPERFAMILY SSF142921 3 74 2.75E-18 T 28-03-2018 IPR008893 WGR domain MKLM6_RS22205 163aa8b2943684d14f119ebe2c885599 80 SMART SM00773 1 80 8.7E-12 T 28-03-2018 IPR008893 WGR domain MKLM6_RS22365 6f290f158b9df5b34d695e2528f67ff6 163 SMART SM00318 26 147 2.1E-30 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold MKLM6_RS22365 6f290f158b9df5b34d695e2528f67ff6 163 ProSitePatterns PS01123 Thermonuclease family signature 1. 37 62 - T 28-03-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 MKLM6_RS22365 6f290f158b9df5b34d695e2528f67ff6 163 Gene3D G3DSA:2.40.50.90 19 152 2.3E-34 T 28-03-2018 IPR035437 Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain MKLM6_RS22365 6f290f158b9df5b34d695e2528f67ff6 163 SUPERFAMILY SSF50199 23 154 4.71E-37 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold MKLM6_RS22365 6f290f158b9df5b34d695e2528f67ff6 163 Pfam PF00565 Staphylococcal nuclease homologue 52 147 7.0E-22 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold MKLM6_RS11310 bc9a8c045e7912aa31411a35b2d7ca10 470 SUPERFAMILY SSF46689 343 386 6.27E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS11310 bc9a8c045e7912aa31411a35b2d7ca10 470 SUPERFAMILY SSF46689 417 467 6.27E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS11310 bc9a8c045e7912aa31411a35b2d7ca10 470 SUPERFAMILY SSF52172 5 175 7.12E-11 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS11310 bc9a8c045e7912aa31411a35b2d7ca10 470 Pfam PF02954 Bacterial regulatory protein, Fis family 427 466 1.0E-12 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS11310 bc9a8c045e7912aa31411a35b2d7ca10 470 Gene3D G3DSA:1.10.8.60 318 373 9.9E-22 T 28-03-2018 MKLM6_RS11310 bc9a8c045e7912aa31411a35b2d7ca10 470 Gene3D G3DSA:1.10.10.60 374 468 1.5E-15 T 28-03-2018 MKLM6_RS11310 bc9a8c045e7912aa31411a35b2d7ca10 470 SUPERFAMILY SSF52540 131 373 3.88E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS11310 bc9a8c045e7912aa31411a35b2d7ca10 470 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 217 232 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MKLM6_RS11310 bc9a8c045e7912aa31411a35b2d7ca10 470 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 155 168 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MKLM6_RS11310 bc9a8c045e7912aa31411a35b2d7ca10 470 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 433 450 9.4E-8 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS11310 bc9a8c045e7912aa31411a35b2d7ca10 470 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 450 470 9.4E-8 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS11310 bc9a8c045e7912aa31411a35b2d7ca10 470 SMART SM00382 151 295 3.0E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS11310 bc9a8c045e7912aa31411a35b2d7ca10 470 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 343 352 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site MKLM6_RS11310 bc9a8c045e7912aa31411a35b2d7ca10 470 Pfam PF00158 Sigma-54 interaction domain 132 298 2.6E-74 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MKLM6_RS11310 bc9a8c045e7912aa31411a35b2d7ca10 470 Gene3D G3DSA:3.40.50.300 129 317 1.3E-28 T 28-03-2018 MKLM6_RS11310 bc9a8c045e7912aa31411a35b2d7ca10 470 Gene3D G3DSA:3.40.50.2300 4 128 1.4E-6 T 28-03-2018 MKLM6_RS11310 bc9a8c045e7912aa31411a35b2d7ca10 470 Pfam PF06490 Flagellar regulatory protein FleQ 6 112 8.9E-15 T 28-03-2018 IPR010518 Flagellar regulatory FleQ MKLM6_RS13990 d988dd8c04d5782bce5e1a7e1ec67414 232 SMART SM00448 6 116 2.0E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS13990 d988dd8c04d5782bce5e1a7e1ec67414 232 Gene3D G3DSA:3.40.50.2300 1 127 9.2E-37 T 28-03-2018 MKLM6_RS13990 d988dd8c04d5782bce5e1a7e1ec67414 232 SUPERFAMILY SSF52172 8 192 1.85E-39 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS13990 d988dd8c04d5782bce5e1a7e1ec67414 232 SMART SM00862 151 227 3.5E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS13990 d988dd8c04d5782bce5e1a7e1ec67414 232 Pfam PF00072 Response regulator receiver domain 8 116 6.4E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS13990 d988dd8c04d5782bce5e1a7e1ec67414 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 227 7.0E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS13990 d988dd8c04d5782bce5e1a7e1ec67414 232 Gene3D G3DSA:1.10.10.10 128 231 2.9E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS18060 279f11f0a7ee08c70382f76db22c16a7 424 SUPERFAMILY SSF53383 230 386 1.69E-52 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS18060 279f11f0a7ee08c70382f76db22c16a7 424 SUPERFAMILY SSF53383 36 191 1.69E-52 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS18060 279f11f0a7ee08c70382f76db22c16a7 424 Gene3D G3DSA:3.40.640.10 18 313 1.7E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS18060 279f11f0a7ee08c70382f76db22c16a7 424 Gene3D G3DSA:3.90.1150.10 314 423 2.5E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS18060 279f11f0a7ee08c70382f76db22c16a7 424 PIRSF PIRSF000390 14 202 9.5E-50 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MKLM6_RS18060 279f11f0a7ee08c70382f76db22c16a7 424 PIRSF PIRSF000390 237 422 5.7E-35 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MKLM6_RS18060 279f11f0a7ee08c70382f76db22c16a7 424 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 29 422 9.6E-85 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MKLM6_RS12990 e6c2e84597257b218d55974f6a2df656 149 TIGRFAM TIGR02944 suf_reg_Xantho: FeS assembly SUF system regulator 1 130 1.2E-48 T 28-03-2018 IPR014290 SUF system FeS cluster assembly regulator MKLM6_RS12990 e6c2e84597257b218d55974f6a2df656 149 SUPERFAMILY SSF46785 3 135 1.02E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS12990 e6c2e84597257b218d55974f6a2df656 149 Pfam PF02082 Transcriptional regulator 3 83 2.6E-19 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type MKLM6_RS12990 e6c2e84597257b218d55974f6a2df656 149 Gene3D G3DSA:1.10.10.10 2 141 5.1E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS12990 e6c2e84597257b218d55974f6a2df656 149 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 3 131 2.8E-30 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type MKLM6_RS05710 4edde5de8f66bd2f1937a2153ca0cd3b 486 SMART SM00267 308 480 5.7E-54 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS05710 4edde5de8f66bd2f1937a2153ca0cd3b 486 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 9 133 5.8E-25 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 MKLM6_RS05710 4edde5de8f66bd2f1937a2153ca0cd3b 486 Gene3D G3DSA:3.30.450.20 168 319 1.4E-20 T 28-03-2018 MKLM6_RS05710 4edde5de8f66bd2f1937a2153ca0cd3b 486 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 192 312 9.2E-8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05710 4edde5de8f66bd2f1937a2153ca0cd3b 486 Pfam PF13426 PAS domain 205 302 1.5E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05710 4edde5de8f66bd2f1937a2153ca0cd3b 486 Pfam PF00990 Diguanylate cyclase, GGDEF domain 319 475 1.8E-41 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS05710 4edde5de8f66bd2f1937a2153ca0cd3b 486 SUPERFAMILY SSF55073 324 479 1.57E-44 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS05710 4edde5de8f66bd2f1937a2153ca0cd3b 486 Pfam PF01814 Hemerythrin HHE cation binding domain 18 133 3.0E-7 T 28-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 MKLM6_RS05710 4edde5de8f66bd2f1937a2153ca0cd3b 486 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 315 476 5.5E-38 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS05710 4edde5de8f66bd2f1937a2153ca0cd3b 486 Gene3D G3DSA:1.20.120.50 1 139 1.2E-27 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 MKLM6_RS05710 4edde5de8f66bd2f1937a2153ca0cd3b 486 SUPERFAMILY SSF55785 183 302 2.09E-19 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05710 4edde5de8f66bd2f1937a2153ca0cd3b 486 SUPERFAMILY SSF47188 4 133 3.66E-24 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 MKLM6_RS05710 4edde5de8f66bd2f1937a2153ca0cd3b 486 Gene3D G3DSA:3.30.70.270 320 485 3.7E-52 T 28-03-2018 MKLM6_RS01675 9b17c1e1e839590dbf329136481a3caf 286 Pfam PF01040 UbiA prenyltransferase family 26 268 1.5E-61 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 MKLM6_RS01675 9b17c1e1e839590dbf329136481a3caf 286 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 9 285 4.2E-101 T 28-03-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 MKLM6_RS01675 9b17c1e1e839590dbf329136481a3caf 286 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 3 286 29.016 T 28-03-2018 IPR031103 4-hydroxybenzoate octaprenyltransferase GO:0004659|GO:0006744|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 Pfam PF00476 DNA polymerase family A 531 907 7.1E-153 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 ProSitePatterns PS00447 DNA polymerase family A signature. 735 754 - T 28-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 SMART SM00279 173 208 3.7E-17 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 SUPERFAMILY SSF53098 314 499 2.89E-57 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 SUPERFAMILY SSF56672 503 909 4.34E-157 T 28-03-2018 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 Gene3D G3DSA:1.20.1060.10 524 637 2.9E-33 T 28-03-2018 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 171 264 6.1E-32 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 TIGRFAM TIGR00593 pola: DNA polymerase I 9 909 1.9E-288 T 28-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 SUPERFAMILY SSF88723 4 170 5.89E-55 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 8 170 7.6E-53 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 Gene3D G3DSA:1.10.150.20 185 262 6.6E-29 T 28-03-2018 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 Gene3D G3DSA:3.40.50.1010 7 184 2.8E-67 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 Gene3D G3DSA:3.30.420.10 322 523 1.1E-53 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 SMART SM00474 311 498 1.6E-37 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 Pfam PF01612 3'-5' exonuclease 311 497 2.3E-40 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 659 674 1.2E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 711 724 1.2E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 772 783 1.2E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 826 842 1.2E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 794 805 1.2E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 856 869 1.2E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 681 704 1.2E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 735 760 1.2E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 636 658 1.2E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 SMART SM00482 667 873 1.0E-117 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 SMART SM00475 7 261 7.3E-131 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 SUPERFAMILY SSF47807 171 285 1.5E-35 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 Gene3D G3DSA:3.30.70.370 638 732 2.6E-18 T 28-03-2018 MKLM6_RS00450 c86d08d8e3501901a6c35b11ebc6cf1c 909 Gene3D G3DSA:3.30.70.370 735 909 8.3E-50 T 28-03-2018 MKLM6_RS05730 7f6be3d4312131ad55828287928ff763 743 Pfam PF00593 TonB dependent receptor 326 741 4.7E-32 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS05730 7f6be3d4312131ad55828287928ff763 743 SUPERFAMILY SSF56935 472 743 7.94E-79 T 28-03-2018 MKLM6_RS05730 7f6be3d4312131ad55828287928ff763 743 SUPERFAMILY SSF56935 41 288 7.94E-79 T 28-03-2018 MKLM6_RS05730 7f6be3d4312131ad55828287928ff763 743 SUPERFAMILY SSF56935 320 443 7.94E-79 T 28-03-2018 MKLM6_RS05730 7f6be3d4312131ad55828287928ff763 743 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 726 743 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site MKLM6_RS05730 7f6be3d4312131ad55828287928ff763 743 Gene3D G3DSA:2.170.130.10 33 154 4.6E-20 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS05730 7f6be3d4312131ad55828287928ff763 743 Pfam PF07715 TonB-dependent Receptor Plug Domain 54 155 1.5E-16 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS05730 7f6be3d4312131ad55828287928ff763 743 Gene3D G3DSA:2.40.170.20 155 743 3.4E-42 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS02200 ebb3d6d74217c7227a18a41b944fbec9 418 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 417 1.0E-211 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 MKLM6_RS02200 ebb3d6d74217c7227a18a41b944fbec9 418 SMART SM00382 170 356 9.4E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS02200 ebb3d6d74217c7227a18a41b944fbec9 418 Gene3D G3DSA:3.40.50.300 129 418 9.2E-56 T 28-03-2018 MKLM6_RS02200 ebb3d6d74217c7227a18a41b944fbec9 418 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 3.3E-23 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MKLM6_RS02200 ebb3d6d74217c7227a18a41b944fbec9 418 SMART SM00959 5 47 2.9E-15 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 MKLM6_RS02200 ebb3d6d74217c7227a18a41b944fbec9 418 SMART SM00357 52 118 7.1E-19 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 MKLM6_RS02200 ebb3d6d74217c7227a18a41b944fbec9 418 SUPERFAMILY SSF50249 48 125 1.71E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS02200 ebb3d6d74217c7227a18a41b944fbec9 418 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 418 244.635 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 MKLM6_RS02200 ebb3d6d74217c7227a18a41b944fbec9 418 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 4.1E-32 T 28-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 MKLM6_RS02200 ebb3d6d74217c7227a18a41b944fbec9 418 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 1.0E-14 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 MKLM6_RS02200 ebb3d6d74217c7227a18a41b944fbec9 418 SUPERFAMILY SSF68912 1 46 1.1E-11 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 MKLM6_RS02200 ebb3d6d74217c7227a18a41b944fbec9 418 SUPERFAMILY SSF52540 90 371 1.46E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS02200 ebb3d6d74217c7227a18a41b944fbec9 418 Gene3D G3DSA:2.40.50.140 2 126 1.1E-45 T 28-03-2018 MKLM6_RS08755 3c0a8c144be72b6efab53c1d33d7dee4 175 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 96 129 1.8E-8 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS08755 3c0a8c144be72b6efab53c1d33d7dee4 175 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 10 45 3.1E-6 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS08755 3c0a8c144be72b6efab53c1d33d7dee4 175 SUPERFAMILY SSF51161 3 173 6.1E-47 T 28-03-2018 IPR011004 Trimeric LpxA-like MKLM6_RS08755 3c0a8c144be72b6efab53c1d33d7dee4 175 Gene3D G3DSA:2.160.10.10 1 175 1.3E-44 T 28-03-2018 MKLM6_RS17340 11f39ab32c5de5a1ed82de77dd64e44d 781 Gene3D G3DSA:1.20.1640.10 201 402 6.7E-21 T 28-03-2018 MKLM6_RS17340 11f39ab32c5de5a1ed82de77dd64e44d 781 Gene3D G3DSA:1.20.1640.10 604 772 2.1E-15 T 28-03-2018 MKLM6_RS17340 11f39ab32c5de5a1ed82de77dd64e44d 781 Pfam PF03176 MMPL family 179 320 7.8E-5 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MKLM6_RS17340 11f39ab32c5de5a1ed82de77dd64e44d 781 SUPERFAMILY SSF82866 247 397 5.89E-20 T 28-03-2018 MKLM6_RS17340 11f39ab32c5de5a1ed82de77dd64e44d 781 SUPERFAMILY SSF82866 612 771 4.58E-16 T 28-03-2018 MKLM6_RS15145 db23eb9718db3337e0b404fd2ed6c260 177 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 142 153 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MKLM6_RS15145 db23eb9718db3337e0b404fd2ed6c260 177 Gene3D G3DSA:1.10.1060.10 144 176 9.5E-6 T 28-03-2018 MKLM6_RS15145 db23eb9718db3337e0b404fd2ed6c260 177 SUPERFAMILY SSF54862 38 171 5.02E-29 T 28-03-2018 MKLM6_RS15145 db23eb9718db3337e0b404fd2ed6c260 177 Hamap MF_00463 Electron transport complex subunit RsxB [rsxB]. 3 177 38.753 T 28-03-2018 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 MKLM6_RS15145 db23eb9718db3337e0b404fd2ed6c260 177 Gene3D G3DSA:3.30.70.20 23 121 3.7E-12 T 28-03-2018 MKLM6_RS15145 db23eb9718db3337e0b404fd2ed6c260 177 Gene3D G3DSA:3.30.70.20 122 143 5.3E-11 T 28-03-2018 MKLM6_RS15145 db23eb9718db3337e0b404fd2ed6c260 177 Pfam PF04060 Putative Fe-S cluster 44 75 4.0E-13 T 28-03-2018 IPR007202 4Fe-4S domain GO:0051536 MKLM6_RS15145 db23eb9718db3337e0b404fd2ed6c260 177 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 3 175 7.6E-65 T 28-03-2018 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 MKLM6_RS15145 db23eb9718db3337e0b404fd2ed6c260 177 Pfam PF14697 4Fe-4S dicluster domain 105 159 2.4E-14 T 28-03-2018 MKLM6_RS15145 db23eb9718db3337e0b404fd2ed6c260 177 PIRSF PIRSF005784 2 177 1.0E-66 T 28-03-2018 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 MKLM6_RS02600 8244e45a0ffdcf9d3564aa2c82f9a38b 487 Gene3D G3DSA:3.40.1670.10 323 459 6.3E-51 T 28-03-2018 MKLM6_RS02600 8244e45a0ffdcf9d3564aa2c82f9a38b 487 SUPERFAMILY SSF50475 3 322 7.45E-126 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MKLM6_RS02600 8244e45a0ffdcf9d3564aa2c82f9a38b 487 Hamap MF_01636 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [ubiD]. 1 487 70.467 T 28-03-2018 IPR023677 UbiD decarboxylyase, bacteria GO:0005886|GO:0006744|GO:0008694 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 MKLM6_RS02600 8244e45a0ffdcf9d3564aa2c82f9a38b 487 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 455 1.7E-172 T 28-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 MKLM6_RS02600 8244e45a0ffdcf9d3564aa2c82f9a38b 487 Gene3D G3DSA:1.20.5.570 460 485 2.8E-14 T 28-03-2018 MKLM6_RS02600 8244e45a0ffdcf9d3564aa2c82f9a38b 487 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 12 431 7.8E-173 T 28-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 MKLM6_RS02600 8244e45a0ffdcf9d3564aa2c82f9a38b 487 SUPERFAMILY SSF143968 323 485 6.15E-66 T 28-03-2018 MKLM6_RS04485 373be64a393d31e7daeb4106ba201f6e 546 SUPERFAMILY SSF52317 288 540 6.64E-90 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS04485 373be64a393d31e7daeb4106ba201f6e 546 Gene3D G3DSA:3.40.50.300 1 284 1.3E-127 T 28-03-2018 MKLM6_RS04485 373be64a393d31e7daeb4106ba201f6e 546 Pfam PF00117 Glutamine amidotransferase class-I 301 534 1.2E-58 T 28-03-2018 IPR017926 Glutamine amidotransferase MKLM6_RS04485 373be64a393d31e7daeb4106ba201f6e 546 Pfam PF06418 CTP synthase N-terminus 3 265 1.1E-124 T 28-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MKLM6_RS04485 373be64a393d31e7daeb4106ba201f6e 546 SUPERFAMILY SSF52540 1 268 1.91E-120 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS04485 373be64a393d31e7daeb4106ba201f6e 546 Gene3D G3DSA:3.40.50.880 285 542 5.2E-75 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS04485 373be64a393d31e7daeb4106ba201f6e 546 TIGRFAM TIGR00337 PyrG: CTP synthase 1 534 8.4E-251 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MKLM6_RS04485 373be64a393d31e7daeb4106ba201f6e 546 Hamap MF_01227 CTP synthase [pyrG]. 2 539 51.504 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MKLM6_RS13720 cd35971fd68fe734c8f032ab7062d06c 143 SUPERFAMILY SSF54995 1 101 1.96E-34 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS13720 cd35971fd68fe734c8f032ab7062d06c 143 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 20.66 T 28-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 MKLM6_RS13720 cd35971fd68fe734c8f032ab7062d06c 143 Pfam PF01250 Ribosomal protein S6 3 90 2.7E-26 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS13720 cd35971fd68fe734c8f032ab7062d06c 143 Gene3D G3DSA:3.30.70.60 1 98 6.4E-29 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 MKLM6_RS13720 cd35971fd68fe734c8f032ab7062d06c 143 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 1.4E-32 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS13720 cd35971fd68fe734c8f032ab7062d06c 143 ProSitePatterns PS01048 Ribosomal protein S6 signature. 43 52 - T 28-03-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 MKLM6_RS13975 2a198d29dcc9c170de5cdfbf0f19fb3f 247 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 16 221 8.3E-28 T 28-03-2018 MKLM6_RS13670 f7ddf3bb97cbe263bc81a0efb113518b 461 PIRSF PIRSF036426 1 461 1.1E-205 T 28-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MKLM6_RS13670 f7ddf3bb97cbe263bc81a0efb113518b 461 Gene3D G3DSA:3.40.1010.10 216 341 1.8E-38 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MKLM6_RS13670 f7ddf3bb97cbe263bc81a0efb113518b 461 SUPERFAMILY SSF53790 215 460 9.95E-86 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MKLM6_RS13670 f7ddf3bb97cbe263bc81a0efb113518b 461 Hamap MF_01646 Siroheme synthase [cysG]. 1 461 53.17 T 28-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MKLM6_RS13670 f7ddf3bb97cbe263bc81a0efb113518b 461 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 207 7.5E-71 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MKLM6_RS13670 f7ddf3bb97cbe263bc81a0efb113518b 461 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 219 428 4.5E-54 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MKLM6_RS13670 f7ddf3bb97cbe263bc81a0efb113518b 461 Gene3D G3DSA:3.40.50.720 1 105 3.7E-19 T 28-03-2018 MKLM6_RS13670 f7ddf3bb97cbe263bc81a0efb113518b 461 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 297 330 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MKLM6_RS13670 f7ddf3bb97cbe263bc81a0efb113518b 461 Gene3D G3DSA:3.30.950.10 342 461 2.4E-44 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MKLM6_RS13670 f7ddf3bb97cbe263bc81a0efb113518b 461 Gene3D G3DSA:1.10.8.210 151 208 2.3E-16 T 28-03-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MKLM6_RS13670 f7ddf3bb97cbe263bc81a0efb113518b 461 SUPERFAMILY SSF75615 114 206 1.96E-24 T 28-03-2018 MKLM6_RS13670 f7ddf3bb97cbe263bc81a0efb113518b 461 Pfam PF13241 Putative NAD(P)-binding 6 115 2.8E-30 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MKLM6_RS13670 f7ddf3bb97cbe263bc81a0efb113518b 461 Pfam PF14824 Sirohaem biosynthesis protein central 119 145 1.6E-7 T 28-03-2018 IPR028281 Siroheme synthase, central domain KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MKLM6_RS13670 f7ddf3bb97cbe263bc81a0efb113518b 461 Gene3D G3DSA:3.30.160.110 106 146 1.3E-17 T 28-03-2018 MKLM6_RS13670 f7ddf3bb97cbe263bc81a0efb113518b 461 SUPERFAMILY SSF51735 1 113 2.14E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS13670 f7ddf3bb97cbe263bc81a0efb113518b 461 Pfam PF10414 Sirohaem synthase dimerisation region 151 207 2.6E-17 T 28-03-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MKLM6_RS13670 f7ddf3bb97cbe263bc81a0efb113518b 461 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 217 452 3.1E-96 T 28-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MKLM6_RS16285 fa4a13c18ce98b98297d2bcdd8e257df 399 Pfam PF00589 Phage integrase family 222 363 2.0E-8 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS16285 fa4a13c18ce98b98297d2bcdd8e257df 399 Gene3D G3DSA:1.10.443.10 204 382 3.8E-22 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS16285 fa4a13c18ce98b98297d2bcdd8e257df 399 Gene3D G3DSA:1.10.150.130 92 203 1.5E-12 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal MKLM6_RS16285 fa4a13c18ce98b98297d2bcdd8e257df 399 Pfam PF13356 Arm DNA-binding domain 7 96 8.5E-16 T 28-03-2018 IPR025166 Integrase, DNA-binding domain MKLM6_RS16285 fa4a13c18ce98b98297d2bcdd8e257df 399 SUPERFAMILY SSF56349 102 372 2.35E-34 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS18395 80928428b3e5386f2f710692849e9074 87 SUPERFAMILY SSF50249 9 84 1.2E-31 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS18395 80928428b3e5386f2f710692849e9074 87 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 9 83 22.958 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18395 80928428b3e5386f2f710692849e9074 87 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 9 79 6.0E-23 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18395 80928428b3e5386f2f710692849e9074 87 Gene3D G3DSA:2.40.50.140 8 85 3.3E-32 T 28-03-2018 MKLM6_RS18395 80928428b3e5386f2f710692849e9074 87 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 9 78 2.0E-33 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18395 80928428b3e5386f2f710692849e9074 87 PRINTS PR00973 Ribosomal protein S17 family signature 69 76 1.6E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18395 80928428b3e5386f2f710692849e9074 87 PRINTS PR00973 Ribosomal protein S17 family signature 59 69 1.6E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18395 80928428b3e5386f2f710692849e9074 87 PRINTS PR00973 Ribosomal protein S17 family signature 27 50 1.6E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18395 80928428b3e5386f2f710692849e9074 87 Pfam PF00366 Ribosomal protein S17 13 80 2.9E-33 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS01315 d90ec252ff180450114f93387499f2d9 557 Pfam PF01268 Formate--tetrahydrofolate ligase 1 557 3.4E-262 T 28-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 MKLM6_RS01315 d90ec252ff180450114f93387499f2d9 557 Gene3D G3DSA:3.10.410.10 446 533 3.1E-32 T 28-03-2018 MKLM6_RS01315 d90ec252ff180450114f93387499f2d9 557 Gene3D G3DSA:3.40.50.300 237 444 5.6E-72 T 28-03-2018 MKLM6_RS01315 d90ec252ff180450114f93387499f2d9 557 Gene3D G3DSA:3.40.50.300 11 236 5.6E-96 T 28-03-2018 MKLM6_RS01315 d90ec252ff180450114f93387499f2d9 557 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 329 340 - T 28-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 MKLM6_RS01315 d90ec252ff180450114f93387499f2d9 557 SUPERFAMILY SSF52540 3 555 2.77E-236 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS01315 d90ec252ff180450114f93387499f2d9 557 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 1 557 47.857 T 28-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 MKLM6_RS01315 d90ec252ff180450114f93387499f2d9 557 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 103 113 - T 28-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 MKLM6_RS14200 aa9ca8b0a9c952531b6b5304e243ea74 143 SUPERFAMILY SSF49367 45 142 3.92E-14 T 28-03-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 MKLM6_RS14200 aa9ca8b0a9c952531b6b5304e243ea74 143 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 2 22 1.5E-5 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal MKLM6_RS14200 aa9ca8b0a9c952531b6b5304e243ea74 143 Pfam PF01880 Desulfoferrodoxin 51 138 1.7E-10 T 28-03-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 MKLM6_RS14200 aa9ca8b0a9c952531b6b5304e243ea74 143 Gene3D G3DSA:2.60.40.730 36 143 3.2E-21 T 28-03-2018 MKLM6_RS05900 1859aecd3ac9ceca69bdd85bf68ade59 561 Gene3D G3DSA:3.90.79.10 126 314 2.1E-10 T 28-03-2018 MKLM6_RS05900 1859aecd3ac9ceca69bdd85bf68ade59 561 SUPERFAMILY SSF55811 145 310 2.89E-9 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MKLM6_RS10270 d7447e9e0e63cdf94f1d621995283ec3 268 Pfam PF00072 Response regulator receiver domain 147 261 2.5E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS10270 d7447e9e0e63cdf94f1d621995283ec3 268 Pfam PF00072 Response regulator receiver domain 11 123 3.5E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS10270 d7447e9e0e63cdf94f1d621995283ec3 268 SMART SM00448 9 123 7.7E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS10270 d7447e9e0e63cdf94f1d621995283ec3 268 SMART SM00448 145 261 1.1E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS10270 d7447e9e0e63cdf94f1d621995283ec3 268 SUPERFAMILY SSF52172 8 129 1.38E-24 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS10270 d7447e9e0e63cdf94f1d621995283ec3 268 Gene3D G3DSA:3.40.50.2300 140 268 7.3E-31 T 28-03-2018 MKLM6_RS10270 d7447e9e0e63cdf94f1d621995283ec3 268 Gene3D G3DSA:3.40.50.2300 5 137 7.2E-22 T 28-03-2018 MKLM6_RS10270 d7447e9e0e63cdf94f1d621995283ec3 268 SUPERFAMILY SSF52172 144 266 9.39E-31 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS05635 a4b443bffb5fde617d97d7321d8f44dc 799 Gene3D G3DSA:3.40.50.300 16 406 5.2E-6 T 28-03-2018 MKLM6_RS05635 a4b443bffb5fde617d97d7321d8f44dc 799 Gene3D G3DSA:3.30.230.10 543 773 1.9E-32 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MKLM6_RS05635 a4b443bffb5fde617d97d7321d8f44dc 799 Pfam PF13654 AAA domain 25 539 3.3E-197 T 28-03-2018 MKLM6_RS05635 a4b443bffb5fde617d97d7321d8f44dc 799 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 706 724 6.0E-12 T 28-03-2018 MKLM6_RS05635 a4b443bffb5fde617d97d7321d8f44dc 799 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 61 80 6.0E-12 T 28-03-2018 MKLM6_RS05635 a4b443bffb5fde617d97d7321d8f44dc 799 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 646 665 6.0E-12 T 28-03-2018 MKLM6_RS05635 a4b443bffb5fde617d97d7321d8f44dc 799 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 676 695 6.0E-12 T 28-03-2018 MKLM6_RS05635 a4b443bffb5fde617d97d7321d8f44dc 799 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 565 581 6.0E-12 T 28-03-2018 MKLM6_RS05635 a4b443bffb5fde617d97d7321d8f44dc 799 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 649 751 3.1E-10 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 MKLM6_RS05635 a4b443bffb5fde617d97d7321d8f44dc 799 SUPERFAMILY SSF52540 31 104 3.3E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS05635 a4b443bffb5fde617d97d7321d8f44dc 799 SUPERFAMILY SSF52540 316 556 3.3E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS05635 a4b443bffb5fde617d97d7321d8f44dc 799 SUPERFAMILY SSF54211 565 756 2.62E-38 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS13250 f84061d6c83d5fff2a2f53f2ba5185b5 406 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 6 389 2.6E-126 T 28-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 MKLM6_RS13250 f84061d6c83d5fff2a2f53f2ba5185b5 406 Pfam PF01494 FAD binding domain 5 339 1.6E-26 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 MKLM6_RS13250 f84061d6c83d5fff2a2f53f2ba5185b5 406 SUPERFAMILY SSF51905 4 176 2.18E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS13250 f84061d6c83d5fff2a2f53f2ba5185b5 406 SUPERFAMILY SSF51905 275 395 2.18E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS13250 f84061d6c83d5fff2a2f53f2ba5185b5 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 4.2E-18 T 28-03-2018 MKLM6_RS13250 f84061d6c83d5fff2a2f53f2ba5185b5 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 4.2E-18 T 28-03-2018 MKLM6_RS13250 f84061d6c83d5fff2a2f53f2ba5185b5 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 4.2E-18 T 28-03-2018 MKLM6_RS13250 f84061d6c83d5fff2a2f53f2ba5185b5 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 4.2E-18 T 28-03-2018 MKLM6_RS13250 f84061d6c83d5fff2a2f53f2ba5185b5 406 Gene3D G3DSA:3.50.50.60 1 361 6.7E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS07305 0666337b015ebb2311176d74064f95c0 960 Pfam PF04453 Organic solvent tolerance protein 477 868 1.3E-93 T 28-03-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 MKLM6_RS07305 0666337b015ebb2311176d74064f95c0 960 Gene3D G3DSA:2.60.450.10 228 386 3.5E-14 T 28-03-2018 MKLM6_RS07305 0666337b015ebb2311176d74064f95c0 960 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 9 937 20.09 T 28-03-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 Pfam PF01627 Hpt domain 1247 1324 1.0E-6 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 SMART SM00388 852 917 1.1E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 SUPERFAMILY SSF55785 721 834 1.42E-24 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 SUPERFAMILY SSF55785 545 675 8.38E-17 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 Gene3D G3DSA:3.40.50.2300 1091 1209 6.7E-44 T 28-03-2018 MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 427 555 9.2E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 711 838 5.2E-13 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 556 684 5.1E-11 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 299 424 1.1E-13 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 SMART SM00387 965 1081 1.6E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 SUPERFAMILY SSF55785 434 551 2.97E-23 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 965 1080 3.9E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 SUPERFAMILY SSF47384 835 918 1.12E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 Pfam PF00072 Response regulator receiver domain 1103 1214 4.7E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 Pfam PF08447 PAS fold 738 826 8.8E-21 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 Pfam PF08447 PAS fold 454 542 6.0E-22 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 Gene3D G3DSA:1.10.287.130 852 913 1.7E-18 T 28-03-2018 MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 Pfam PF13426 PAS domain 575 676 3.2E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 SUPERFAMILY SSF47226 1197 1309 4.58E-14 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 Pfam PF00512 His Kinase A (phospho-acceptor) domain 852 916 3.8E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 SUPERFAMILY SSF52172 1100 1219 1.57E-42 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 Gene3D G3DSA:3.30.450.20 286 421 2.5E-29 T 28-03-2018 MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 SMART SM00091 560 625 0.4 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 SMART SM00091 302 368 3.8E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 SMART SM00091 429 498 9.6E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 SMART SM00091 714 783 1.3E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 Gene3D G3DSA:3.30.565.10 921 1089 4.2E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 Pfam PF05231 MASE1 13 291 6.9E-19 T 28-03-2018 IPR007895 MASE1 MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 Pfam PF08448 PAS fold 308 418 2.4E-19 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 Gene3D G3DSA:3.30.450.20 422 551 5.4E-36 T 28-03-2018 MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 Gene3D G3DSA:3.30.450.20 699 851 7.1E-39 T 28-03-2018 MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 Gene3D G3DSA:3.30.450.20 552 698 2.7E-20 T 28-03-2018 MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 SUPERFAMILY SSF55785 287 415 9.77E-26 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 SUPERFAMILY SSF55874 906 1079 3.8E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 SMART SM00448 1101 1214 7.9E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1006 1020 2.1E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1065 1078 2.1E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1041 1059 2.1E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1024 1034 2.1E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 Gene3D G3DSA:1.20.120.160 1210 1335 1.9E-12 T 28-03-2018 MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 SMART SM00086 374 417 370.0 T 28-03-2018 IPR001610 PAC motif MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 SMART SM00086 505 548 1.6E-8 T 28-03-2018 IPR001610 PAC motif MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 SMART SM00086 789 832 2.3E-10 T 28-03-2018 IPR001610 PAC motif MKLM6_RS13960 0e504a78d5947ea428d052086d0b58ac 1431 SMART SM00086 637 677 3.4 T 28-03-2018 IPR001610 PAC motif MKLM6_RS20735 4aaf9f415f7e430df851064e446a4a28 83 Gene3D G3DSA:1.20.1270.70 5 82 5.7E-4 T 28-03-2018 MKLM6_RS20735 4aaf9f415f7e430df851064e446a4a28 83 Pfam PF04380 Membrane fusogenic activity 1 78 1.4E-30 T 28-03-2018 IPR007475 Membrane fusogenic activity MKLM6_RS17505 d924685608ebad53278e2229b6b5c7d0 83 SUPERFAMILY SSF118196 1 66 1.57E-14 T 28-03-2018 IPR023370 TsaA-like domain MKLM6_RS17505 d924685608ebad53278e2229b6b5c7d0 83 Gene3D G3DSA:2.40.30.70 1 56 3.1E-13 T 28-03-2018 IPR023370 TsaA-like domain MKLM6_RS17505 d924685608ebad53278e2229b6b5c7d0 83 Pfam PF01980 Uncharacterised protein family UPF0066 1 38 6.2E-8 T 28-03-2018 IPR023370 TsaA-like domain MKLM6_RS20830 47cd36d65fde7d98f8cd376aed66db8b 726 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 339 397 3.7E-10 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 MKLM6_RS20830 47cd36d65fde7d98f8cd376aed66db8b 726 Gene3D G3DSA:2.40.50.180 614 662 3.6E-16 T 28-03-2018 MKLM6_RS20830 47cd36d65fde7d98f8cd376aed66db8b 726 PRINTS PR00344 Bacterial sensor protein C-terminal signature 489 503 6.7E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS20830 47cd36d65fde7d98f8cd376aed66db8b 726 PRINTS PR00344 Bacterial sensor protein C-terminal signature 529 539 6.7E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS20830 47cd36d65fde7d98f8cd376aed66db8b 726 PRINTS PR00344 Bacterial sensor protein C-terminal signature 545 563 6.7E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS20830 47cd36d65fde7d98f8cd376aed66db8b 726 PRINTS PR00344 Bacterial sensor protein C-terminal signature 569 582 6.7E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS20830 47cd36d65fde7d98f8cd376aed66db8b 726 Gene3D G3DSA:3.30.565.10 399 584 7.0E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS20830 47cd36d65fde7d98f8cd376aed66db8b 726 Gene3D G3DSA:1.20.120.160 3 152 6.0E-30 T 28-03-2018 MKLM6_RS20830 47cd36d65fde7d98f8cd376aed66db8b 726 SUPERFAMILY SSF47384 340 400 4.32E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS20830 47cd36d65fde7d98f8cd376aed66db8b 726 SUPERFAMILY SSF50341 584 709 2.35E-28 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS20830 47cd36d65fde7d98f8cd376aed66db8b 726 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 447 584 1.7E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS20830 47cd36d65fde7d98f8cd376aed66db8b 726 SMART SM00073 7 104 4.1E-24 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS20830 47cd36d65fde7d98f8cd376aed66db8b 726 SMART SM00260 577 710 6.1E-28 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS20830 47cd36d65fde7d98f8cd376aed66db8b 726 Gene3D G3DSA:2.30.30.40 585 613 0.35 T 28-03-2018 MKLM6_RS20830 47cd36d65fde7d98f8cd376aed66db8b 726 Gene3D G3DSA:2.30.30.40 663 710 7.8E-17 T 28-03-2018 MKLM6_RS20830 47cd36d65fde7d98f8cd376aed66db8b 726 Gene3D G3DSA:1.10.287.560 339 398 1.3E-12 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 MKLM6_RS20830 47cd36d65fde7d98f8cd376aed66db8b 726 Pfam PF01584 CheW-like domain 590 713 2.5E-23 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS20830 47cd36d65fde7d98f8cd376aed66db8b 726 SUPERFAMILY SSF47226 13 135 6.41E-28 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS20830 47cd36d65fde7d98f8cd376aed66db8b 726 Pfam PF01627 Hpt domain 12 94 8.1E-16 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS20830 47cd36d65fde7d98f8cd376aed66db8b 726 SMART SM01231 339 399 5.0E-13 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 MKLM6_RS20830 47cd36d65fde7d98f8cd376aed66db8b 726 SUPERFAMILY SSF55874 401 583 1.06E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS20830 47cd36d65fde7d98f8cd376aed66db8b 726 SMART SM00387 444 585 1.2E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS03625 068f360e43fba893aa0dfb2bf4864125 220 Gene3D G3DSA:3.40.50.2300 2 117 4.5E-27 T 28-03-2018 MKLM6_RS03625 068f360e43fba893aa0dfb2bf4864125 220 SUPERFAMILY SSF46894 136 202 7.48E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MKLM6_RS03625 068f360e43fba893aa0dfb2bf4864125 220 Pfam PF00072 Response regulator receiver domain 12 121 1.0E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS03625 068f360e43fba893aa0dfb2bf4864125 220 SMART SM00421 145 202 3.9E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS03625 068f360e43fba893aa0dfb2bf4864125 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 198 6.7E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS03625 068f360e43fba893aa0dfb2bf4864125 220 SUPERFAMILY SSF52172 9 146 9.11E-31 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS03625 068f360e43fba893aa0dfb2bf4864125 220 SMART SM00448 10 121 2.4E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS03625 068f360e43fba893aa0dfb2bf4864125 220 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS03625 068f360e43fba893aa0dfb2bf4864125 220 Gene3D G3DSA:1.10.10.10 118 212 2.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS03625 068f360e43fba893aa0dfb2bf4864125 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 6.7E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS03625 068f360e43fba893aa0dfb2bf4864125 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 6.7E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS03625 068f360e43fba893aa0dfb2bf4864125 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 6.7E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS19910 abe1332877bacf007602c8a5311192cd 241 Gene3D G3DSA:3.40.50.300 2 237 5.7E-58 T 28-03-2018 MKLM6_RS19910 abe1332877bacf007602c8a5311192cd 241 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 4 241 2.7E-115 T 28-03-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 MKLM6_RS19910 abe1332877bacf007602c8a5311192cd 241 SMART SM00382 28 213 8.8E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS19910 abe1332877bacf007602c8a5311192cd 241 SUPERFAMILY SSF52540 4 237 1.42E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS19910 abe1332877bacf007602c8a5311192cd 241 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS19910 abe1332877bacf007602c8a5311192cd 241 Pfam PF00005 ABC transporter 20 166 3.6E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS19815 cc7b4a949585995f5e26c538089bba40 472 SMART SM00878 335 441 2.1E-60 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MKLM6_RS19815 cc7b4a949585995f5e26c538089bba40 472 Pfam PF02785 Biotin carboxylase C-terminal domain 335 441 1.1E-38 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MKLM6_RS19815 cc7b4a949585995f5e26c538089bba40 472 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 321 2.3E-76 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MKLM6_RS19815 cc7b4a949585995f5e26c538089bba40 472 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MKLM6_RS19815 cc7b4a949585995f5e26c538089bba40 472 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 109 3.6E-43 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MKLM6_RS19815 cc7b4a949585995f5e26c538089bba40 472 Gene3D G3DSA:3.40.50.20 1 117 4.8E-50 T 28-03-2018 MKLM6_RS19815 cc7b4a949585995f5e26c538089bba40 472 SUPERFAMILY SSF56059 82 347 2.3E-67 T 28-03-2018 MKLM6_RS19815 cc7b4a949585995f5e26c538089bba40 472 SUPERFAMILY SSF52440 1 112 2.3E-45 T 28-03-2018 IPR016185 Pre-ATP-grasp domain MKLM6_RS19815 cc7b4a949585995f5e26c538089bba40 472 Gene3D G3DSA:3.30.470.20 204 443 1.3E-96 T 28-03-2018 MKLM6_RS19815 cc7b4a949585995f5e26c538089bba40 472 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 442 8.6E-193 T 28-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 MKLM6_RS19815 cc7b4a949585995f5e26c538089bba40 472 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MKLM6_RS19815 cc7b4a949585995f5e26c538089bba40 472 SUPERFAMILY SSF51246 330 447 2.3E-42 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MKLM6_RS19815 cc7b4a949585995f5e26c538089bba40 472 Gene3D G3DSA:3.30.1490.20 118 203 5.1E-21 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MKLM6_RS06560 2268b1a4587535ca1a555ca2184abbea 479 SMART SM00345 8 67 1.3E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MKLM6_RS06560 2268b1a4587535ca1a555ca2184abbea 479 Gene3D G3DSA:3.40.640.10 123 373 6.5E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS06560 2268b1a4587535ca1a555ca2184abbea 479 Gene3D G3DSA:1.10.10.10 1 69 1.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS06560 2268b1a4587535ca1a555ca2184abbea 479 Gene3D G3DSA:3.90.1150.10 374 472 1.6E-28 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS06560 2268b1a4587535ca1a555ca2184abbea 479 Pfam PF00155 Aminotransferase class I and II 108 464 1.1E-32 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MKLM6_RS06560 2268b1a4587535ca1a555ca2184abbea 479 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 67 3.8E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MKLM6_RS06560 2268b1a4587535ca1a555ca2184abbea 479 SUPERFAMILY SSF46785 3 76 6.47E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS06560 2268b1a4587535ca1a555ca2184abbea 479 SUPERFAMILY SSF53383 94 469 7.48E-93 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 Pfam PF00873 AcrB/AcrD/AcrF family 6 1028 4.5E-293 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 Gene3D G3DSA:3.30.2090.10 189 276 2.2E-12 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 Gene3D G3DSA:3.30.2090.10 724 810 2.7E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 1.3E-38 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 PRINTS PR00702 Acriflavin resistance protein family signature 341 364 1.3E-38 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 1.3E-38 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 PRINTS PR00702 Acriflavin resistance protein family signature 396 420 1.3E-38 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 PRINTS PR00702 Acriflavin resistance protein family signature 368 389 1.3E-38 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 PRINTS PR00702 Acriflavin resistance protein family signature 621 635 1.3E-38 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 PRINTS PR00702 Acriflavin resistance protein family signature 478 501 1.3E-38 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 PRINTS PR00702 Acriflavin resistance protein family signature 551 568 1.3E-38 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 SUPERFAMILY SSF82693 43 128 7.32E-19 T 28-03-2018 MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 SUPERFAMILY SSF82693 577 666 3.77E-6 T 28-03-2018 MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 SUPERFAMILY SSF82866 807 1031 3.27E-57 T 28-03-2018 MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 SUPERFAMILY SSF82866 299 504 3.53E-41 T 28-03-2018 MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 SUPERFAMILY SSF82693 159 190 1.88E-13 T 28-03-2018 MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 SUPERFAMILY SSF82693 276 335 1.88E-13 T 28-03-2018 MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 Gene3D G3DSA:3.30.70.1430 567 669 1.3E-11 T 28-03-2018 MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 Gene3D G3DSA:1.20.1640.10 292 516 6.4E-43 T 28-03-2018 MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 Gene3D G3DSA:1.20.1640.10 827 1039 6.6E-40 T 28-03-2018 MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 SUPERFAMILY SSF82714 191 274 1.57E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 Gene3D G3DSA:3.30.70.1430 42 142 8.2E-20 T 28-03-2018 MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1033 0.0 T 28-03-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 MKLM6_RS02165 83f4292813e01d9ff745d75e61acc972 1041 SUPERFAMILY SSF82714 725 808 9.29E-16 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS11100 32a31bc03591bbe606761860e91be1f1 305 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 131 245 3.8E-18 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 MKLM6_RS11100 32a31bc03591bbe606761860e91be1f1 305 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 14 113 1.6E-22 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 MKLM6_RS11100 32a31bc03591bbe606761860e91be1f1 305 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 11 276 1.8E-106 T 28-03-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 MKLM6_RS11100 32a31bc03591bbe606761860e91be1f1 305 SUPERFAMILY SSF52374 11 290 9.12E-82 T 28-03-2018 MKLM6_RS11100 32a31bc03591bbe606761860e91be1f1 305 Gene3D G3DSA:3.40.50.620 157 296 2.0E-21 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS11100 32a31bc03591bbe606761860e91be1f1 305 Gene3D G3DSA:3.40.50.620 6 148 7.1E-31 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS11100 32a31bc03591bbe606761860e91be1f1 305 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 11 296 40.482 T 28-03-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 MKLM6_RS11100 32a31bc03591bbe606761860e91be1f1 305 PRINTS PR00987 Glutamyl-tRNA synthetase signature 28 39 5.4E-16 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MKLM6_RS11100 32a31bc03591bbe606761860e91be1f1 305 PRINTS PR00987 Glutamyl-tRNA synthetase signature 14 26 5.4E-16 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MKLM6_RS11100 32a31bc03591bbe606761860e91be1f1 305 PRINTS PR00987 Glutamyl-tRNA synthetase signature 43 56 5.4E-16 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MKLM6_RS11100 32a31bc03591bbe606761860e91be1f1 305 PRINTS PR00987 Glutamyl-tRNA synthetase signature 176 186 5.4E-16 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MKLM6_RS11100 32a31bc03591bbe606761860e91be1f1 305 PRINTS PR00987 Glutamyl-tRNA synthetase signature 192 200 5.4E-16 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MKLM6_RS07035 e3929db9f4a9b7520e124bddb787c6c6 535 Pfam PF09721 Transmembrane exosortase (Exosortase_EpsH) 20 275 2.8E-65 T 28-03-2018 IPR019127 Exosortase EpsH-related MKLM6_RS07035 e3929db9f4a9b7520e124bddb787c6c6 535 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 181 276 2.5E-23 T 28-03-2018 IPR026392 Exosortase/Archaeosortase domain MKLM6_RS07035 e3929db9f4a9b7520e124bddb787c6c6 535 Pfam PF11984 Protein of unknown function (DUF3485) 315 518 5.6E-52 T 28-03-2018 IPR014263 Methanolan biosynthesis EpsI MKLM6_RS07035 e3929db9f4a9b7520e124bddb787c6c6 535 TIGRFAM TIGR02914 EpsI_fam: EpsI family protein 344 516 4.7E-38 T 28-03-2018 IPR014263 Methanolan biosynthesis EpsI MKLM6_RS07035 e3929db9f4a9b7520e124bddb787c6c6 535 TIGRFAM TIGR04152 exosort_VPLPA: exosortase D, VPLPA-CTERM-specific 36 521 6.4E-179 T 28-03-2018 IPR026491 Exosortase D, VPLPA-CTERM-specific MKLM6_RS07035 e3929db9f4a9b7520e124bddb787c6c6 535 TIGRFAM TIGR02602 8TM_EpsH: exosortase 35 270 4.0E-51 T 28-03-2018 IPR013426 Exosortase, EpsH MKLM6_RS01345 9d3da3756c8d6a45e5ab6aedb186e4d5 759 Pfam PF00593 TonB dependent receptor 246 757 7.4E-36 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS01345 9d3da3756c8d6a45e5ab6aedb186e4d5 759 SUPERFAMILY SSF56935 36 759 3.43E-93 T 28-03-2018 MKLM6_RS01345 9d3da3756c8d6a45e5ab6aedb186e4d5 759 Gene3D G3DSA:2.170.130.10 32 168 2.3E-20 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS01345 9d3da3756c8d6a45e5ab6aedb186e4d5 759 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 742 759 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site MKLM6_RS01345 9d3da3756c8d6a45e5ab6aedb186e4d5 759 Pfam PF07715 TonB-dependent Receptor Plug Domain 54 161 1.4E-15 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS01345 9d3da3756c8d6a45e5ab6aedb186e4d5 759 Gene3D G3DSA:2.40.170.20 176 759 3.6E-61 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS12645 78d59b1660fae817a864290172d26d6a 421 Gene3D G3DSA:3.40.1190.10 1 286 7.1E-79 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MKLM6_RS12645 78d59b1660fae817a864290172d26d6a 421 SUPERFAMILY SSF53623 6 284 7.46E-86 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MKLM6_RS12645 78d59b1660fae817a864290172d26d6a 421 Pfam PF08245 Mur ligase middle domain 48 261 9.2E-10 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MKLM6_RS12645 78d59b1660fae817a864290172d26d6a 421 PIRSF PIRSF001563 1 421 7.9E-112 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 MKLM6_RS12645 78d59b1660fae817a864290172d26d6a 421 TIGRFAM TIGR01499 folC: bifunctional protein FolC 28 417 3.4E-105 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 MKLM6_RS12645 78d59b1660fae817a864290172d26d6a 421 Pfam PF02875 Mur ligase family, glutamate ligase domain 287 346 6.6E-7 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MKLM6_RS12645 78d59b1660fae817a864290172d26d6a 421 Gene3D G3DSA:3.90.190.20 288 421 3.9E-26 T 28-03-2018 MKLM6_RS12645 78d59b1660fae817a864290172d26d6a 421 SUPERFAMILY SSF53244 287 418 6.56E-28 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MKLM6_RS13220 d7494e72a9f44545edd677eccea28983 185 SUPERFAMILY SSF55194 3 183 1.02E-69 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 MKLM6_RS13220 d7494e72a9f44545edd677eccea28983 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 26.935 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 MKLM6_RS13220 d7494e72a9f44545edd677eccea28983 185 Gene3D G3DSA:1.10.132.20 73 184 5.4E-38 T 28-03-2018 MKLM6_RS13220 d7494e72a9f44545edd677eccea28983 185 Gene3D G3DSA:1.10.132.20 2 72 1.2E-9 T 28-03-2018 MKLM6_RS13220 d7494e72a9f44545edd677eccea28983 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 12 184 1.4E-69 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 MKLM6_RS13220 d7494e72a9f44545edd677eccea28983 185 Pfam PF01765 Ribosome recycling factor 20 183 3.9E-63 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 MKLM6_RS12735 af4fedaf72364a4b6443aeda27471bc3 385 Pfam PF12832 MFS_1 like family 5 358 1.5E-84 T 28-03-2018 IPR024989 Major facilitator superfamily associated domain MKLM6_RS12735 af4fedaf72364a4b6443aeda27471bc3 385 Gene3D G3DSA:1.20.1250.20 3 189 1.0E-15 T 28-03-2018 MKLM6_RS12735 af4fedaf72364a4b6443aeda27471bc3 385 PIRSF PIRSF004925 2 384 1.7E-105 T 28-03-2018 IPR026032 Probable 3-phenylpropionic acid transporter MKLM6_RS12735 af4fedaf72364a4b6443aeda27471bc3 385 SUPERFAMILY SSF103473 5 376 2.09E-41 T 28-03-2018 IPR020846 Major facilitator superfamily domain MKLM6_RS12735 af4fedaf72364a4b6443aeda27471bc3 385 Gene3D G3DSA:1.20.1250.20 190 384 6.7E-19 T 28-03-2018 MKLM6_RS02075 2396760d342c20cb88bf58690efb3a80 51 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS02075 2396760d342c20cb88bf58690efb3a80 51 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 51 4.8E-25 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS02075 2396760d342c20cb88bf58690efb3a80 51 SUPERFAMILY SSF57829 1 49 1.1E-19 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 MKLM6_RS02075 2396760d342c20cb88bf58690efb3a80 51 Pfam PF00471 Ribosomal protein L33 4 49 4.0E-19 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS02075 2396760d342c20cb88bf58690efb3a80 51 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 15.691 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS02290 96f74725a08b13d0436888895f387254 349 Pfam PF01212 Beta-eliminating lyase 3 293 2.2E-53 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 MKLM6_RS02290 96f74725a08b13d0436888895f387254 349 Gene3D G3DSA:3.40.640.10 1 246 1.8E-29 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS02290 96f74725a08b13d0436888895f387254 349 Gene3D G3DSA:3.90.1150.10 247 349 5.0E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS02290 96f74725a08b13d0436888895f387254 349 PIRSF PIRSF038940 1 349 5.5E-146 T 28-03-2018 IPR026273 Low specificity L-threonine aldolase GO:0004793|GO:0006567 KEGG: 00260+4.1.2.48 MKLM6_RS02290 96f74725a08b13d0436888895f387254 349 SUPERFAMILY SSF53383 1 348 6.46E-91 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS08795 5b3dfedba15d225f16174a0b9e497166 129 TIGRFAM TIGR03012 sulf_tusD_dsrE: sulfur relay protein TusD/DsrE 2 128 2.6E-39 T 28-03-2018 IPR017463 Sulphur relay, TusD/DsrE GO:0005737|GO:0008033|GO:0016783 MKLM6_RS08795 5b3dfedba15d225f16174a0b9e497166 129 Pfam PF02635 DsrE/DsrF-like family 1 128 8.7E-24 T 28-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein MKLM6_RS08795 5b3dfedba15d225f16174a0b9e497166 129 Gene3D G3DSA:3.40.1260.10 1 129 1.6E-26 T 28-03-2018 MKLM6_RS08795 5b3dfedba15d225f16174a0b9e497166 129 SUPERFAMILY SSF75169 1 128 3.03E-35 T 28-03-2018 IPR027396 DsrEFH-like MKLM6_RS05660 7288be70d7babd65e1ec5f70764a000b 366 SMART SM00471 169 320 2.3E-7 T 28-03-2018 IPR003607 HD/PDEase domain MKLM6_RS05660 7288be70d7babd65e1ec5f70764a000b 366 Gene3D G3DSA:3.40.50.2300 3 139 7.7E-32 T 28-03-2018 MKLM6_RS05660 7288be70d7babd65e1ec5f70764a000b 366 SUPERFAMILY SSF109604 155 347 1.1E-30 T 28-03-2018 MKLM6_RS05660 7288be70d7babd65e1ec5f70764a000b 366 Gene3D G3DSA:1.10.3210.10 140 361 9.3E-43 T 28-03-2018 MKLM6_RS05660 7288be70d7babd65e1ec5f70764a000b 366 SUPERFAMILY SSF52172 6 152 6.69E-36 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS05660 7288be70d7babd65e1ec5f70764a000b 366 Pfam PF01966 HD domain 174 309 4.3E-18 T 28-03-2018 IPR006674 HD domain MKLM6_RS05660 7288be70d7babd65e1ec5f70764a000b 366 SMART SM00448 7 120 1.1E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS05660 7288be70d7babd65e1ec5f70764a000b 366 Pfam PF00072 Response regulator receiver domain 10 116 1.4E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS07080 834688c63cb2d6ccb6bab55ee7d18770 272 SUPERFAMILY SSF50199 46 180 7.85E-34 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold MKLM6_RS07080 834688c63cb2d6ccb6bab55ee7d18770 272 Pfam PF00565 Staphylococcal nuclease homologue 71 178 1.6E-24 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold MKLM6_RS07080 834688c63cb2d6ccb6bab55ee7d18770 272 Gene3D G3DSA:2.40.50.90 50 193 4.6E-33 T 28-03-2018 IPR035437 Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain MKLM6_RS07080 834688c63cb2d6ccb6bab55ee7d18770 272 ProSitePatterns PS01284 Thermonuclease family signature 2. 119 129 - T 28-03-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 MKLM6_RS07080 834688c63cb2d6ccb6bab55ee7d18770 272 SMART SM00318 49 178 1.2E-26 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold MKLM6_RS07080 834688c63cb2d6ccb6bab55ee7d18770 272 Pfam PF13511 Domain of unknown function (DUF4124) 8 36 1.8E-7 T 28-03-2018 IPR025392 Domain of unknown function DUF4124 MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 Pfam PF00873 AcrB/AcrD/AcrF family 11 1013 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 Gene3D G3DSA:3.30.2090.10 187 273 7.4E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 SUPERFAMILY SSF82714 708 790 1.57E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 Gene3D G3DSA:1.20.1640.10 806 1025 5.4E-33 T 28-03-2018 MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 SUPERFAMILY SSF82714 189 269 1.96E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 Gene3D G3DSA:3.30.70.1430 46 148 1.7E-22 T 28-03-2018 MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 Gene3D G3DSA:3.30.70.1430 560 656 1.0E-7 T 28-03-2018 MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 SUPERFAMILY SSF82866 296 496 1.23E-45 T 28-03-2018 MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 SUPERFAMILY SSF82693 46 140 5.23E-22 T 28-03-2018 MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 PRINTS PR00702 Acriflavin resistance protein family signature 44 62 6.7E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 6.7E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 6.7E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 PRINTS PR00702 Acriflavin resistance protein family signature 544 561 6.7E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 PRINTS PR00702 Acriflavin resistance protein family signature 444 467 6.7E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 PRINTS PR00702 Acriflavin resistance protein family signature 16 40 6.7E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 6.7E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 PRINTS PR00702 Acriflavin resistance protein family signature 469 492 6.7E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 PRINTS PR00702 Acriflavin resistance protein family signature 611 625 6.7E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 Gene3D G3DSA:1.20.1640.10 274 499 1.1E-44 T 28-03-2018 MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 SUPERFAMILY SSF82693 557 650 5.75E-11 T 28-03-2018 MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 Gene3D G3DSA:3.30.2090.10 708 794 2.4E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 SUPERFAMILY SSF82866 794 1018 1.7E-41 T 28-03-2018 MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 SUPERFAMILY SSF82693 142 188 7.06E-22 T 28-03-2018 MKLM6_RS16970 bcbf396e164de2d60eb26e009f7740e3 1025 SUPERFAMILY SSF82693 274 330 7.06E-22 T 28-03-2018 MKLM6_RS19885 dde0235cace18ca52976e87f533c1751 247 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 9 101 1.8E-19 T 28-03-2018 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 MKLM6_RS19885 dde0235cace18ca52976e87f533c1751 247 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 12 247 24.849 T 28-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 MKLM6_RS19885 dde0235cace18ca52976e87f533c1751 247 Gene3D G3DSA:2.160.20.70 129 247 1.1E-34 T 28-03-2018 MKLM6_RS19885 dde0235cace18ca52976e87f533c1751 247 SUPERFAMILY SSF63848 144 246 1.57E-31 T 28-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 MKLM6_RS19885 dde0235cace18ca52976e87f533c1751 247 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 146 244 1.5E-32 T 28-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 MKLM6_RS19885 dde0235cace18ca52976e87f533c1751 247 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 13 246 1.3E-68 T 28-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 MKLM6_RS08645 518ed90164afe447678394240f07cecc 178 Pfam PF02441 Flavoprotein 5 116 9.6E-13 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MKLM6_RS08645 518ed90164afe447678394240f07cecc 178 SUPERFAMILY SSF52507 3 124 4.58E-17 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MKLM6_RS08645 518ed90164afe447678394240f07cecc 178 Gene3D G3DSA:3.40.50.1950 1 176 5.7E-20 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MKLM6_RS05375 e6fd5ab892d8e8ff29c2d556fc728f19 189 Pfam PF11659 Protein of unknown function (DUF3261) 45 183 3.9E-35 T 28-03-2018 IPR021675 Protein of unknown function DUF3261 MKLM6_RS16250 4bb3882de39221424dd046719d01c216 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 206 1.7E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS16250 4bb3882de39221424dd046719d01c216 218 SUPERFAMILY SSF46894 139 213 1.39E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MKLM6_RS16250 4bb3882de39221424dd046719d01c216 218 Pfam PF00072 Response regulator receiver domain 7 118 3.1E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS16250 4bb3882de39221424dd046719d01c216 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 3.0E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS16250 4bb3882de39221424dd046719d01c216 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 3.0E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS16250 4bb3882de39221424dd046719d01c216 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 3.0E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS16250 4bb3882de39221424dd046719d01c216 218 SUPERFAMILY SSF52172 4 135 1.08E-31 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS16250 4bb3882de39221424dd046719d01c216 218 SMART SM00421 150 207 1.0E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS16250 4bb3882de39221424dd046719d01c216 218 Gene3D G3DSA:1.10.10.10 130 217 8.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS16250 4bb3882de39221424dd046719d01c216 218 Gene3D G3DSA:3.40.50.2300 4 129 1.9E-28 T 28-03-2018 MKLM6_RS16250 4bb3882de39221424dd046719d01c216 218 SMART SM00448 5 118 2.6E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS20595 f8a575549d974d27dc7ed7b4c1afa6db 322 Pfam PF08867 FRG domain 37 131 1.4E-16 T 28-03-2018 IPR014966 FRG domain MKLM6_RS20595 f8a575549d974d27dc7ed7b4c1afa6db 322 SMART SM00901 34 135 1.9E-12 T 28-03-2018 IPR014966 FRG domain MKLM6_RS01425 5ad68d768136a67b3aaf3feb8bb562c2 359 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 8 352 1.1E-161 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 MKLM6_RS01425 5ad68d768136a67b3aaf3feb8bb562c2 359 Gene3D G3DSA:3.20.20.70 10 357 1.7E-130 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS01425 5ad68d768136a67b3aaf3feb8bb562c2 359 Pfam PF00793 DAHP synthetase I family 43 340 8.7E-101 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MKLM6_RS01425 5ad68d768136a67b3aaf3feb8bb562c2 359 PIRSF PIRSF001361 1 355 2.6E-160 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 MKLM6_RS01425 5ad68d768136a67b3aaf3feb8bb562c2 359 SUPERFAMILY SSF51569 9 351 9.11E-135 T 28-03-2018 MKLM6_RS10860 84925b9b2df495d9af024dd735d4f962 165 SMART SM01001 3 154 1.5E-103 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MKLM6_RS10860 84925b9b2df495d9af024dd735d4f962 165 Gene3D G3DSA:3.40.50.7700 1 161 8.6E-67 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MKLM6_RS10860 84925b9b2df495d9af024dd735d4f962 165 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 158 32.039 T 28-03-2018 IPR033747 Class I PurE MKLM6_RS10860 84925b9b2df495d9af024dd735d4f962 165 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 158 9.6E-66 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MKLM6_RS10860 84925b9b2df495d9af024dd735d4f962 165 Pfam PF00731 AIR carboxylase 5 152 4.8E-65 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MKLM6_RS10860 84925b9b2df495d9af024dd735d4f962 165 PIRSF PIRSF001338 1 163 3.7E-66 T 28-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 MKLM6_RS10860 84925b9b2df495d9af024dd735d4f962 165 SUPERFAMILY SSF52255 4 160 3.4E-66 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MKLM6_RS07325 7cfcf7f662d41bd08ca637d445f4e9e9 382 Pfam PF00570 HRDC domain 213 279 5.5E-17 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MKLM6_RS07325 7cfcf7f662d41bd08ca637d445f4e9e9 382 Gene3D G3DSA:3.30.420.10 1 192 1.0E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS07325 7cfcf7f662d41bd08ca637d445f4e9e9 382 SUPERFAMILY SSF47819 303 367 4.91E-10 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 MKLM6_RS07325 7cfcf7f662d41bd08ca637d445f4e9e9 382 TIGRFAM TIGR01388 rnd: ribonuclease D 6 364 3.0E-111 T 28-03-2018 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 MKLM6_RS07325 7cfcf7f662d41bd08ca637d445f4e9e9 382 Pfam PF01612 3'-5' exonuclease 4 170 1.0E-36 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MKLM6_RS07325 7cfcf7f662d41bd08ca637d445f4e9e9 382 SMART SM00341 210 290 1.1E-9 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MKLM6_RS07325 7cfcf7f662d41bd08ca637d445f4e9e9 382 Gene3D G3DSA:1.10.150.80 195 291 9.7E-24 T 28-03-2018 MKLM6_RS07325 7cfcf7f662d41bd08ca637d445f4e9e9 382 SUPERFAMILY SSF47819 195 289 7.41E-25 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 MKLM6_RS07325 7cfcf7f662d41bd08ca637d445f4e9e9 382 Hamap MF_01899 Ribonuclease D [rnd]. 3 365 39.533 T 28-03-2018 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 MKLM6_RS07325 7cfcf7f662d41bd08ca637d445f4e9e9 382 SMART SM00474 3 171 2.4E-34 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MKLM6_RS07325 7cfcf7f662d41bd08ca637d445f4e9e9 382 SUPERFAMILY SSF53098 2 209 1.08E-66 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS11215 f4c90c56f0e2cc862045af35bf722422 415 Pfam PF00872 Transposase, Mutator family 13 375 1.0E-66 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS00750 f4c90c56f0e2cc862045af35bf722422 415 Pfam PF00872 Transposase, Mutator family 13 375 1.0E-66 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS06950 f4c90c56f0e2cc862045af35bf722422 415 Pfam PF00872 Transposase, Mutator family 13 375 1.0E-66 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS13485 f4c90c56f0e2cc862045af35bf722422 415 Pfam PF00872 Transposase, Mutator family 13 375 1.0E-66 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS13035 f4c90c56f0e2cc862045af35bf722422 415 Pfam PF00872 Transposase, Mutator family 13 375 1.0E-66 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS09260 f4c90c56f0e2cc862045af35bf722422 415 Pfam PF00872 Transposase, Mutator family 13 375 1.0E-66 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS00275 f4c90c56f0e2cc862045af35bf722422 415 Pfam PF00872 Transposase, Mutator family 13 375 1.0E-66 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS04260 f4c90c56f0e2cc862045af35bf722422 415 Pfam PF00872 Transposase, Mutator family 13 375 1.0E-66 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS00225 f4c90c56f0e2cc862045af35bf722422 415 Pfam PF00872 Transposase, Mutator family 13 375 1.0E-66 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS07570 f4c90c56f0e2cc862045af35bf722422 415 Pfam PF00872 Transposase, Mutator family 13 375 1.0E-66 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS04820 f4c90c56f0e2cc862045af35bf722422 415 Pfam PF00872 Transposase, Mutator family 13 375 1.0E-66 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS11560 f4c90c56f0e2cc862045af35bf722422 415 Pfam PF00872 Transposase, Mutator family 13 375 1.0E-66 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS04170 f4c90c56f0e2cc862045af35bf722422 415 Pfam PF00872 Transposase, Mutator family 13 375 1.0E-66 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS11525 f4c90c56f0e2cc862045af35bf722422 415 Pfam PF00872 Transposase, Mutator family 13 375 1.0E-66 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS06550 27f866b8cdb76ef3672ed7c13d59c1c2 95 TIGRFAM TIGR04042 MSMEG_0570_fam: MSMEG_0570 family protein 2 90 2.3E-38 T 28-03-2018 IPR023846 Conserved hypothetical protein CHP04042, MSMEG0570 MKLM6_RS01195 7546166d419eb3069aacea30c5ff9af9 522 SUPERFAMILY SSF52540 396 488 1.02E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS01195 7546166d419eb3069aacea30c5ff9af9 522 SUPERFAMILY SSF52540 328 367 1.02E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS01195 7546166d419eb3069aacea30c5ff9af9 522 Pfam PF13671 AAA domain 334 484 1.9E-29 T 28-03-2018 MKLM6_RS01195 7546166d419eb3069aacea30c5ff9af9 522 Gene3D G3DSA:3.40.50.300 334 500 2.6E-19 T 28-03-2018 MKLM6_RS01195 7546166d419eb3069aacea30c5ff9af9 522 Pfam PF01636 Phosphotransferase enzyme family 124 228 1.1E-6 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase MKLM6_RS01195 7546166d419eb3069aacea30c5ff9af9 522 Gene3D G3DSA:3.90.1200.10 122 333 6.8E-15 T 28-03-2018 MKLM6_RS01195 7546166d419eb3069aacea30c5ff9af9 522 SUPERFAMILY SSF56112 7 327 5.44E-20 T 28-03-2018 IPR011009 Protein kinase-like domain MKLM6_RS18325 53042bc7029f8ff68a2d009c59393928 128 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 8 128 32.379 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18325 53042bc7029f8ff68a2d009c59393928 128 PIRSF PIRSF002131 1 128 5.2E-52 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18325 53042bc7029f8ff68a2d009c59393928 128 ProSitePatterns PS00054 Ribosomal protein S11 signature. 96 118 - T 28-03-2018 IPR018102 Ribosomal S11, conserved site MKLM6_RS18325 53042bc7029f8ff68a2d009c59393928 128 SUPERFAMILY SSF53137 14 128 6.28E-47 T 28-03-2018 MKLM6_RS18325 53042bc7029f8ff68a2d009c59393928 128 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 9 125 2.2E-55 T 28-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18325 53042bc7029f8ff68a2d009c59393928 128 Gene3D G3DSA:3.30.420.80 2 128 2.5E-44 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18325 53042bc7029f8ff68a2d009c59393928 128 Pfam PF00411 Ribosomal protein S11 18 127 8.2E-50 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MKLM6_RS19215 627b3d547fe8c690c09171da8af76c15 412 SUPERFAMILY SSF109604 226 382 6.48E-31 T 28-03-2018 MKLM6_RS19215 627b3d547fe8c690c09171da8af76c15 412 SMART SM00471 22 151 2.9 T 28-03-2018 IPR003607 HD/PDEase domain MKLM6_RS19215 627b3d547fe8c690c09171da8af76c15 412 SMART SM00471 232 367 1.6E-13 T 28-03-2018 IPR003607 HD/PDEase domain MKLM6_RS19215 627b3d547fe8c690c09171da8af76c15 412 Gene3D G3DSA:1.10.3210.10 188 408 4.1E-41 T 28-03-2018 MKLM6_RS19215 627b3d547fe8c690c09171da8af76c15 412 Gene3D G3DSA:1.10.3210.10 24 187 2.8E-18 T 28-03-2018 MKLM6_RS19215 627b3d547fe8c690c09171da8af76c15 412 Pfam PF01966 HD domain 29 143 2.4E-6 T 28-03-2018 IPR006674 HD domain MKLM6_RS19215 627b3d547fe8c690c09171da8af76c15 412 Pfam PF01966 HD domain 239 357 2.0E-19 T 28-03-2018 IPR006674 HD domain MKLM6_RS19215 627b3d547fe8c690c09171da8af76c15 412 TIGRFAM TIGR00277 HDIG: HDIG domain 236 326 2.0E-8 T 28-03-2018 IPR006675 HDIG domain MKLM6_RS19215 627b3d547fe8c690c09171da8af76c15 412 SUPERFAMILY SSF109604 14 182 3.71E-17 T 28-03-2018 MKLM6_RS14220 ce6f574497b22ba7f6899dd6c7178184 115 Pfam PF07883 Cupin domain 48 108 6.2E-8 T 28-03-2018 IPR013096 Cupin 2, conserved barrel MKLM6_RS14220 ce6f574497b22ba7f6899dd6c7178184 115 SUPERFAMILY SSF51182 16 114 7.99E-21 T 28-03-2018 IPR011051 RmlC-like cupin domain MKLM6_RS14220 ce6f574497b22ba7f6899dd6c7178184 115 Gene3D G3DSA:2.60.120.10 6 115 9.2E-17 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS03945 7d2bb879277f2451cff38bc410244fe2 152 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 110 120 - T 28-03-2018 IPR020549 Endoribonuclease YbeY, conserved site MKLM6_RS03945 7d2bb879277f2451cff38bc410244fe2 152 Pfam PF02130 Uncharacterized protein family UPF0054 16 140 5.3E-37 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MKLM6_RS03945 7d2bb879277f2451cff38bc410244fe2 152 SUPERFAMILY SSF55486 14 146 3.17E-44 T 28-03-2018 MKLM6_RS03945 7d2bb879277f2451cff38bc410244fe2 152 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 36 140 4.9E-34 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MKLM6_RS03945 7d2bb879277f2451cff38bc410244fe2 152 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 3 144 23.452 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MKLM6_RS03945 7d2bb879277f2451cff38bc410244fe2 152 Gene3D G3DSA:3.40.390.30 2 151 6.2E-50 T 28-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 MKLM6_RS03960 c0e9023ae9fac8ea4b95035f1971ce64 345 Gene3D G3DSA:3.40.190.10 152 293 2.1E-30 T 28-03-2018 MKLM6_RS03960 c0e9023ae9fac8ea4b95035f1971ce64 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 75 89 1.1E-8 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MKLM6_RS03960 c0e9023ae9fac8ea4b95035f1971ce64 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 34 50 1.1E-8 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MKLM6_RS03960 c0e9023ae9fac8ea4b95035f1971ce64 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 127 143 1.1E-8 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MKLM6_RS03960 c0e9023ae9fac8ea4b95035f1971ce64 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 256 275 1.1E-8 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MKLM6_RS03960 c0e9023ae9fac8ea4b95035f1971ce64 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 152 166 1.1E-8 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MKLM6_RS03960 c0e9023ae9fac8ea4b95035f1971ce64 345 SUPERFAMILY SSF53850 31 338 6.21E-53 T 28-03-2018 MKLM6_RS03960 c0e9023ae9fac8ea4b95035f1971ce64 345 Pfam PF13416 Bacterial extracellular solute-binding protein 45 297 1.3E-28 T 28-03-2018 MKLM6_RS03960 c0e9023ae9fac8ea4b95035f1971ce64 345 Gene3D G3DSA:3.40.190.10 22 151 1.6E-16 T 28-03-2018 MKLM6_RS14975 51ac0eb539ff4c224cf4c8f956dc0dfd 351 Pfam PF08448 PAS fold 6 104 2.0E-9 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS14975 51ac0eb539ff4c224cf4c8f956dc0dfd 351 Gene3D G3DSA:1.10.287.130 119 188 1.3E-12 T 28-03-2018 MKLM6_RS14975 51ac0eb539ff4c224cf4c8f956dc0dfd 351 Gene3D G3DSA:3.30.565.10 189 346 2.8E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14975 51ac0eb539ff4c224cf4c8f956dc0dfd 351 SMART SM00388 127 192 2.1E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS14975 51ac0eb539ff4c224cf4c8f956dc0dfd 351 Gene3D G3DSA:3.30.450.20 2 118 1.2E-12 T 28-03-2018 MKLM6_RS14975 51ac0eb539ff4c224cf4c8f956dc0dfd 351 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 232 346 4.1E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14975 51ac0eb539ff4c224cf4c8f956dc0dfd 351 SUPERFAMILY SSF55785 5 102 4.71E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14975 51ac0eb539ff4c224cf4c8f956dc0dfd 351 PRINTS PR00344 Bacterial sensor protein C-terminal signature 330 343 1.3E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14975 51ac0eb539ff4c224cf4c8f956dc0dfd 351 PRINTS PR00344 Bacterial sensor protein C-terminal signature 307 325 1.3E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14975 51ac0eb539ff4c224cf4c8f956dc0dfd 351 PRINTS PR00344 Bacterial sensor protein C-terminal signature 278 292 1.3E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14975 51ac0eb539ff4c224cf4c8f956dc0dfd 351 Pfam PF00512 His Kinase A (phospho-acceptor) domain 130 185 6.8E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS14975 51ac0eb539ff4c224cf4c8f956dc0dfd 351 SUPERFAMILY SSF47384 119 188 1.39E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS14975 51ac0eb539ff4c224cf4c8f956dc0dfd 351 SMART SM00387 231 346 4.7E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14975 51ac0eb539ff4c224cf4c8f956dc0dfd 351 SUPERFAMILY SSF55874 195 344 2.36E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS19460 aad51be72af44a823fcf2327a37c8e85 98 Pfam PF04471 Restriction endonuclease 6 59 1.5E-13 T 28-03-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 MKLM6_RS19460 aad51be72af44a823fcf2327a37c8e85 98 Gene3D G3DSA:3.40.1350.10 2 69 8.2E-9 T 28-03-2018 MKLM6_RS17225 ca6e6e27d7e2f56dae6c82fe430eb6b4 293 Pfam PF01841 Transglutaminase-like superfamily 148 245 1.2E-19 T 28-03-2018 IPR002931 Transglutaminase-like MKLM6_RS17225 ca6e6e27d7e2f56dae6c82fe430eb6b4 293 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 3 81 1.1E-23 T 28-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal MKLM6_RS17225 ca6e6e27d7e2f56dae6c82fe430eb6b4 293 SMART SM00460 177 247 1.8E-19 T 28-03-2018 IPR002931 Transglutaminase-like MKLM6_RS17225 ca6e6e27d7e2f56dae6c82fe430eb6b4 293 SUPERFAMILY SSF54001 116 272 3.92E-44 T 28-03-2018 MKLM6_RS17225 ca6e6e27d7e2f56dae6c82fe430eb6b4 293 Gene3D G3DSA:3.90.260.10 166 258 3.2E-5 T 28-03-2018 IPR002931 Transglutaminase-like MKLM6_RS15665 9f296217d813d9437870ebfa544267ad 772 Gene3D G3DSA:2.40.50.140 97 163 6.3E-4 T 28-03-2018 MKLM6_RS15665 9f296217d813d9437870ebfa544267ad 772 Hamap MF_01895 Ribonuclease R [rnr]. 50 729 55.624 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 MKLM6_RS15665 9f296217d813d9437870ebfa544267ad 772 Pfam PF00575 S1 RNA binding domain 646 727 1.1E-11 T 28-03-2018 IPR003029 S1 domain GO:0003676 MKLM6_RS15665 9f296217d813d9437870ebfa544267ad 772 TIGRFAM TIGR02063 RNase_R: ribonuclease R 31 729 6.6E-264 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 MKLM6_RS15665 9f296217d813d9437870ebfa544267ad 772 Gene3D G3DSA:1.10.10.10 30 92 4.6E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS15665 9f296217d813d9437870ebfa544267ad 772 SMART SM00357 98 157 2.2E-13 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 MKLM6_RS15665 9f296217d813d9437870ebfa544267ad 772 Pfam PF08206 Ribonuclease B OB domain 99 156 1.4E-19 T 28-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain MKLM6_RS15665 9f296217d813d9437870ebfa544267ad 772 SUPERFAMILY SSF50249 79 159 9.73E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS15665 9f296217d813d9437870ebfa544267ad 772 Gene3D G3DSA:2.40.50.140 648 769 1.9E-19 T 28-03-2018 MKLM6_RS15665 9f296217d813d9437870ebfa544267ad 772 Pfam PF08461 Ribonuclease R winged-helix domain 35 89 1.9E-7 T 28-03-2018 IPR013668 Ribonuclease R winged-helix domain MKLM6_RS15665 9f296217d813d9437870ebfa544267ad 772 SMART SM00955 272 600 2.4E-175 T 28-03-2018 MKLM6_RS15665 9f296217d813d9437870ebfa544267ad 772 SUPERFAMILY SSF50249 150 248 1.41E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS15665 9f296217d813d9437870ebfa544267ad 772 Pfam PF00773 RNB domain 272 599 1.9E-105 T 28-03-2018 MKLM6_RS15665 9f296217d813d9437870ebfa544267ad 772 SUPERFAMILY SSF50249 232 645 7.42E-141 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS15665 9f296217d813d9437870ebfa544267ad 772 ProSitePatterns PS01175 Ribonuclease II family signature. 567 591 - T 28-03-2018 IPR022966 Ribonuclease II/R, conserved site MKLM6_RS15665 9f296217d813d9437870ebfa544267ad 772 SUPERFAMILY SSF50249 648 728 2.07E-19 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS15665 9f296217d813d9437870ebfa544267ad 772 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 86 729 1.0E-225 T 28-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 MKLM6_RS15665 9f296217d813d9437870ebfa544267ad 772 SMART SM00316 646 729 6.1E-13 T 28-03-2018 IPR022967 RNA-binding domain, S1 MKLM6_RS14835 6663817a7c0f66f899d2f707a13c49aa 235 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 117 200 8.9E-13 T 28-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis MKLM6_RS14835 6663817a7c0f66f899d2f707a13c49aa 235 SUPERFAMILY SSF53146 105 219 1.57E-26 T 28-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis MKLM6_RS14835 6663817a7c0f66f899d2f707a13c49aa 235 Pfam PF16844 Dinitrogenase iron-molybdenum cofactor, N-terminal 4 94 9.0E-33 T 28-03-2018 IPR031763 Dinitrogenase iron-molybdenum cofactor, N-terminal MKLM6_RS14835 6663817a7c0f66f899d2f707a13c49aa 235 Gene3D G3DSA:3.30.420.130 102 221 3.2E-26 T 28-03-2018 MKLM6_RS16815 f18f3059b92a97b999c2cb122a0101e3 201 Pfam PF00574 Clp protease 19 198 7.9E-89 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA MKLM6_RS16815 f18f3059b92a97b999c2cb122a0101e3 201 SUPERFAMILY SSF52096 17 200 8.45E-75 T 28-03-2018 IPR029045 ClpP/crotonase-like domain MKLM6_RS16815 f18f3059b92a97b999c2cb122a0101e3 201 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 9 199 44.758 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MKLM6_RS16815 f18f3059b92a97b999c2cb122a0101e3 201 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 96 107 - T 28-03-2018 IPR018215 ClpP, Ser active site MKLM6_RS16815 f18f3059b92a97b999c2cb122a0101e3 201 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 9 197 4.9E-106 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MKLM6_RS16815 f18f3059b92a97b999c2cb122a0101e3 201 PRINTS PR00127 Clp protease catalytic subunit P signature 25 40 5.5E-54 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MKLM6_RS16815 f18f3059b92a97b999c2cb122a0101e3 201 PRINTS PR00127 Clp protease catalytic subunit P signature 96 113 5.5E-54 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MKLM6_RS16815 f18f3059b92a97b999c2cb122a0101e3 201 PRINTS PR00127 Clp protease catalytic subunit P signature 117 136 5.5E-54 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MKLM6_RS16815 f18f3059b92a97b999c2cb122a0101e3 201 PRINTS PR00127 Clp protease catalytic subunit P signature 65 85 5.5E-54 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MKLM6_RS16815 f18f3059b92a97b999c2cb122a0101e3 201 PRINTS PR00127 Clp protease catalytic subunit P signature 174 193 5.5E-54 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MKLM6_RS16815 f18f3059b92a97b999c2cb122a0101e3 201 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 118 131 - T 28-03-2018 IPR033135 ClpP, histidine active site MKLM6_RS16815 f18f3059b92a97b999c2cb122a0101e3 201 Gene3D G3DSA:3.90.226.10 8 200 3.8E-46 T 28-03-2018 MKLM6_RS16935 b3c0665314570cce40a47107a9d6ab1e 337 Gene3D G3DSA:3.40.50.2000 161 335 7.9E-47 T 28-03-2018 MKLM6_RS16935 b3c0665314570cce40a47107a9d6ab1e 337 TIGRFAM TIGR02195 heptsyl_trn_II: lipopolysaccharide heptosyltransferase II 7 334 1.2E-144 T 28-03-2018 IPR011910 ADP-heptose--LPS heptosyltransferase 2 GO:0009103|GO:0016757 MKLM6_RS16935 b3c0665314570cce40a47107a9d6ab1e 337 Gene3D G3DSA:3.40.50.2000 1 152 4.8E-29 T 28-03-2018 MKLM6_RS16935 b3c0665314570cce40a47107a9d6ab1e 337 SUPERFAMILY SSF53756 6 334 1.99E-97 T 28-03-2018 MKLM6_RS16935 b3c0665314570cce40a47107a9d6ab1e 337 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 73 317 1.3E-70 T 28-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 MKLM6_RS11810 374beac6e3538ca48c8330ddb4e7ac45 461 Gene3D G3DSA:3.40.50.620 2 134 1.7E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS11810 374beac6e3538ca48c8330ddb4e7ac45 461 Pfam PF03441 FAD binding domain of DNA photolyase 265 453 2.8E-76 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 MKLM6_RS11810 374beac6e3538ca48c8330ddb4e7ac45 461 SUPERFAMILY SSF48173 199 455 1.57E-96 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 MKLM6_RS11810 374beac6e3538ca48c8330ddb4e7ac45 461 SUPERFAMILY SSF52425 8 169 1.26E-46 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 MKLM6_RS11810 374beac6e3538ca48c8330ddb4e7ac45 461 Pfam PF00875 DNA photolyase 10 163 2.6E-42 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 MKLM6_RS11810 374beac6e3538ca48c8330ddb4e7ac45 461 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 313 325 - T 28-03-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal MKLM6_RS11810 374beac6e3538ca48c8330ddb4e7ac45 461 Gene3D G3DSA:1.10.579.10 282 456 2.3E-68 T 28-03-2018 MKLM6_RS11810 374beac6e3538ca48c8330ddb4e7ac45 461 PRINTS PR00147 DNA photolyase signature 313 329 8.2E-26 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MKLM6_RS11810 374beac6e3538ca48c8330ddb4e7ac45 461 PRINTS PR00147 DNA photolyase signature 146 162 8.2E-26 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MKLM6_RS11810 374beac6e3538ca48c8330ddb4e7ac45 461 PRINTS PR00147 DNA photolyase signature 333 351 8.2E-26 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MKLM6_RS11810 374beac6e3538ca48c8330ddb4e7ac45 461 PRINTS PR00147 DNA photolyase signature 372 386 8.2E-26 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MKLM6_RS11810 374beac6e3538ca48c8330ddb4e7ac45 461 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 333 352 - T 28-03-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal MKLM6_RS11810 374beac6e3538ca48c8330ddb4e7ac45 461 Gene3D G3DSA:1.25.40.80 136 281 1.0E-32 T 28-03-2018 MKLM6_RS17240 14d5773ef8eb4f586df02e93bbd2a194 207 Pfam PF00719 Inorganic pyrophosphatase 26 198 1.4E-45 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MKLM6_RS17240 14d5773ef8eb4f586df02e93bbd2a194 207 Gene3D G3DSA:3.90.80.10 7 203 1.7E-51 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MKLM6_RS17240 14d5773ef8eb4f586df02e93bbd2a194 207 SUPERFAMILY SSF50324 6 200 9.55E-51 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MKLM6_RS17240 14d5773ef8eb4f586df02e93bbd2a194 207 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 90 96 - T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MKLM6_RS14865 e3a6a2deb9aa0008ebd85d361a3a3ea4 162 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 60 67 - T 28-03-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 MKLM6_RS14865 e3a6a2deb9aa0008ebd85d361a3a3ea4 162 Pfam PF00255 Glutathione peroxidase 4 111 8.2E-45 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MKLM6_RS14865 e3a6a2deb9aa0008ebd85d361a3a3ea4 162 PIRSF PIRSF000303 1 162 2.6E-68 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MKLM6_RS14865 e3a6a2deb9aa0008ebd85d361a3a3ea4 162 Gene3D G3DSA:3.40.30.10 2 161 1.9E-49 T 28-03-2018 MKLM6_RS14865 e3a6a2deb9aa0008ebd85d361a3a3ea4 162 PRINTS PR01011 Glutathione peroxidase family signature 57 73 8.8E-21 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MKLM6_RS14865 e3a6a2deb9aa0008ebd85d361a3a3ea4 162 PRINTS PR01011 Glutathione peroxidase family signature 22 39 8.8E-21 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MKLM6_RS14865 e3a6a2deb9aa0008ebd85d361a3a3ea4 162 PRINTS PR01011 Glutathione peroxidase family signature 123 132 8.8E-21 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MKLM6_RS14865 e3a6a2deb9aa0008ebd85d361a3a3ea4 162 SUPERFAMILY SSF52833 3 159 2.46E-63 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS14865 e3a6a2deb9aa0008ebd85d361a3a3ea4 162 ProSitePatterns PS00460 Glutathione peroxidases active site. 24 39 - T 28-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 MKLM6_RS19490 fdbca831cebd3c783f351cef44b61104 129 PIRSF PIRSF002030 1 129 6.4E-43 T 28-03-2018 IPR016339 Truncated hemoglobin, group 1 MKLM6_RS19490 fdbca831cebd3c783f351cef44b61104 129 Pfam PF01152 Bacterial-like globin 11 125 1.1E-18 T 28-03-2018 IPR001486 Truncated hemoglobin GO:0019825 MKLM6_RS19490 fdbca831cebd3c783f351cef44b61104 129 Gene3D G3DSA:1.10.490.10 1 129 1.1E-36 T 28-03-2018 MKLM6_RS19490 fdbca831cebd3c783f351cef44b61104 129 SUPERFAMILY SSF46458 10 127 4.06E-33 T 28-03-2018 IPR009050 Globin-like MKLM6_RS02635 872d77f7019b2ed601ce092c3bad1bea 297 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 17 287 30.589 T 28-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 MKLM6_RS02635 872d77f7019b2ed601ce092c3bad1bea 297 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 22 104 3.2E-24 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 MKLM6_RS02635 872d77f7019b2ed601ce092c3bad1bea 297 Gene3D G3DSA:3.40.50.720 126 291 5.8E-26 T 28-03-2018 MKLM6_RS02635 872d77f7019b2ed601ce092c3bad1bea 297 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 133 208 1.1E-7 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase MKLM6_RS02635 872d77f7019b2ed601ce092c3bad1bea 297 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 20 280 9.0E-76 T 28-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 MKLM6_RS02635 872d77f7019b2ed601ce092c3bad1bea 297 SUPERFAMILY SSF51735 118 283 3.32E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS02635 872d77f7019b2ed601ce092c3bad1bea 297 SUPERFAMILY SSF53223 14 117 7.48E-31 T 28-03-2018 MKLM6_RS02635 872d77f7019b2ed601ce092c3bad1bea 297 Gene3D G3DSA:3.40.50.10860 8 125 8.6E-38 T 28-03-2018 MKLM6_RS22640 a1a989cc9211425e86adc9bef0ca1385 169 SUPERFAMILY SSF109854 4 167 3.94E-59 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MKLM6_RS22640 a1a989cc9211425e86adc9bef0ca1385 169 Gene3D G3DSA:1.20.120.450 2 169 5.3E-64 T 28-03-2018 MKLM6_RS22640 a1a989cc9211425e86adc9bef0ca1385 169 Pfam PF09351 Domain of unknown function (DUF1993) 5 165 3.7E-59 T 28-03-2018 IPR018531 Domain of unknown function DUF1993 MKLM6_RS00600 70d87c673216b55a067ec54bdedc8b73 258 SUPERFAMILY SSF52540 1 253 1.99E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS00600 70d87c673216b55a067ec54bdedc8b73 258 PIRSF PIRSF009320 88 258 1.6E-7 T 28-03-2018 MKLM6_RS00600 70d87c673216b55a067ec54bdedc8b73 258 PIRSF PIRSF009320 2 100 4.1E-15 T 28-03-2018 MKLM6_RS00600 70d87c673216b55a067ec54bdedc8b73 258 Gene3D G3DSA:3.40.50.300 1 258 2.8E-60 T 28-03-2018 MKLM6_RS00600 70d87c673216b55a067ec54bdedc8b73 258 Pfam PF13614 AAA domain 3 177 2.0E-63 T 28-03-2018 IPR025669 AAA domain MKLM6_RS06690 ccdeaea03627ef3e89d102eb65082d49 205 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 7 202 1.4E-106 T 28-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 MKLM6_RS06690 ccdeaea03627ef3e89d102eb65082d49 205 Hamap MF_01389 Urease accessory protein UreG [ureG]. 5 203 48.31 T 28-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 MKLM6_RS06690 ccdeaea03627ef3e89d102eb65082d49 205 PIRSF PIRSF005624 1 204 4.7E-49 T 28-03-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 MKLM6_RS06690 ccdeaea03627ef3e89d102eb65082d49 205 Gene3D G3DSA:3.40.50.300 6 203 1.4E-19 T 28-03-2018 MKLM6_RS06690 ccdeaea03627ef3e89d102eb65082d49 205 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 9 179 2.5E-38 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain MKLM6_RS06690 ccdeaea03627ef3e89d102eb65082d49 205 SUPERFAMILY SSF52540 3 198 1.81E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS10570 eddb6271a2ca7aa0c89db1a5550986cd 305 Pfam PF02567 Phenazine biosynthesis-like protein 9 299 4.7E-47 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MKLM6_RS10570 eddb6271a2ca7aa0c89db1a5550986cd 305 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 1 302 2.1E-52 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MKLM6_RS10570 eddb6271a2ca7aa0c89db1a5550986cd 305 PIRSF PIRSF016184 1 303 5.9E-62 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MKLM6_RS10570 eddb6271a2ca7aa0c89db1a5550986cd 305 SUPERFAMILY SSF54506 1 301 6.97E-47 T 28-03-2018 MKLM6_RS10570 eddb6271a2ca7aa0c89db1a5550986cd 305 Gene3D G3DSA:3.10.310.10 134 292 1.3E-25 T 28-03-2018 MKLM6_RS10570 eddb6271a2ca7aa0c89db1a5550986cd 305 Gene3D G3DSA:3.10.310.10 1 133 2.8E-21 T 28-03-2018 MKLM6_RS02945 25b01d4ea83ab5f2d6bfbee68561dbe4 215 SUPERFAMILY SSF51366 1 212 3.6E-42 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MKLM6_RS02945 25b01d4ea83ab5f2d6bfbee68561dbe4 215 SMART SM00934 5 206 5.5E-42 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MKLM6_RS02945 25b01d4ea83ab5f2d6bfbee68561dbe4 215 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 6 209 8.7E-85 T 28-03-2018 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 MKLM6_RS02945 25b01d4ea83ab5f2d6bfbee68561dbe4 215 Gene3D G3DSA:3.20.20.70 5 211 7.8E-36 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS02945 25b01d4ea83ab5f2d6bfbee68561dbe4 215 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 6 206 7.0E-29 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MKLM6_RS01995 16f63a613b355be0d30120889a13b20a 457 SUPERFAMILY SSF55073 299 455 7.45E-49 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS01995 16f63a613b355be0d30120889a13b20a 457 SMART SM00267 283 456 7.5E-63 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS01995 16f63a613b355be0d30120889a13b20a 457 Gene3D G3DSA:3.30.450.40 128 290 7.6E-8 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS01995 16f63a613b355be0d30120889a13b20a 457 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 291 455 7.8E-53 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS01995 16f63a613b355be0d30120889a13b20a 457 Gene3D G3DSA:3.30.450.20 5 127 4.7E-22 T 28-03-2018 MKLM6_RS01995 16f63a613b355be0d30120889a13b20a 457 SMART SM00091 9 75 5.4E-6 T 28-03-2018 IPR000014 PAS domain MKLM6_RS01995 16f63a613b355be0d30120889a13b20a 457 SUPERFAMILY SSF55781 132 289 1.22E-6 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS01995 16f63a613b355be0d30120889a13b20a 457 Pfam PF00990 Diguanylate cyclase, GGDEF domain 295 452 6.5E-46 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS01995 16f63a613b355be0d30120889a13b20a 457 Gene3D G3DSA:3.30.70.270 291 457 6.2E-55 T 28-03-2018 MKLM6_RS01995 16f63a613b355be0d30120889a13b20a 457 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 12 128 4.6E-17 T 28-03-2018 IPR000014 PAS domain MKLM6_RS01995 16f63a613b355be0d30120889a13b20a 457 SUPERFAMILY SSF55785 10 119 6.88E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS01995 16f63a613b355be0d30120889a13b20a 457 Pfam PF00989 PAS fold 12 118 6.3E-12 T 28-03-2018 IPR013767 PAS fold GO:0006355 MKLM6_RS14375 cc98992b218de7ecc860edab1dfcbd45 315 Gene3D G3DSA:3.40.50.1820 20 312 9.8E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS14375 cc98992b218de7ecc860edab1dfcbd45 315 Pfam PF12146 Serine aminopeptidase, S33 49 286 1.8E-58 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 MKLM6_RS14375 cc98992b218de7ecc860edab1dfcbd45 315 PRINTS PR00111 Alpha/beta hydrolase fold signature 126 139 8.2E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS14375 cc98992b218de7ecc860edab1dfcbd45 315 PRINTS PR00111 Alpha/beta hydrolase fold signature 78 93 8.2E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS14375 cc98992b218de7ecc860edab1dfcbd45 315 PRINTS PR00111 Alpha/beta hydrolase fold signature 239 253 8.2E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS14375 cc98992b218de7ecc860edab1dfcbd45 315 SUPERFAMILY SSF53474 15 304 2.24E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS18640 1e4a632276d6187431a5644e0bfbe66b 290 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 28-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site MKLM6_RS18640 1e4a632276d6187431a5644e0bfbe66b 290 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 4.2E-38 T 28-03-2018 MKLM6_RS18640 1e4a632276d6187431a5644e0bfbe66b 290 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 4.2E-38 T 28-03-2018 MKLM6_RS18640 1e4a632276d6187431a5644e0bfbe66b 290 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 4.2E-38 T 28-03-2018 MKLM6_RS18640 1e4a632276d6187431a5644e0bfbe66b 290 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 4.2E-38 T 28-03-2018 MKLM6_RS18640 1e4a632276d6187431a5644e0bfbe66b 290 Gene3D G3DSA:3.40.50.261 120 290 4.0E-54 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MKLM6_RS18640 1e4a632276d6187431a5644e0bfbe66b 290 Pfam PF02629 CoA binding domain 6 99 7.0E-28 T 28-03-2018 IPR003781 CoA-binding GO:0048037 MKLM6_RS18640 1e4a632276d6187431a5644e0bfbe66b 290 SMART SM00881 4 100 5.0E-32 T 28-03-2018 IPR003781 CoA-binding GO:0048037 MKLM6_RS18640 1e4a632276d6187431a5644e0bfbe66b 290 SUPERFAMILY SSF51735 1 122 1.76E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS18640 1e4a632276d6187431a5644e0bfbe66b 290 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 286 4.2E-141 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MKLM6_RS18640 1e4a632276d6187431a5644e0bfbe66b 290 Pfam PF00549 CoA-ligase 151 271 1.1E-19 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MKLM6_RS18640 1e4a632276d6187431a5644e0bfbe66b 290 Gene3D G3DSA:3.40.50.720 1 119 2.2E-41 T 28-03-2018 MKLM6_RS18640 1e4a632276d6187431a5644e0bfbe66b 290 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 28-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site MKLM6_RS18640 1e4a632276d6187431a5644e0bfbe66b 290 SUPERFAMILY SSF52210 123 285 6.15E-55 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MKLM6_RS18640 1e4a632276d6187431a5644e0bfbe66b 290 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 288 42.247 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MKLM6_RS18640 1e4a632276d6187431a5644e0bfbe66b 290 PIRSF PIRSF001553 1 290 9.5E-130 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MKLM6_RS10355 c1514e1f6df2469166babea3f5491ce9 260 SUPERFAMILY SSF52540 40 227 3.51E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS10355 c1514e1f6df2469166babea3f5491ce9 260 Gene3D G3DSA:3.40.50.300 1 252 4.2E-86 T 28-03-2018 MKLM6_RS10355 c1514e1f6df2469166babea3f5491ce9 260 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 10 235 3.5E-107 T 28-03-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 MKLM6_RS10355 c1514e1f6df2469166babea3f5491ce9 260 PIRSF PIRSF028756 1 260 3.9E-106 T 28-03-2018 IPR016898 Polyphosphate kinase 2 MKLM6_RS10355 c1514e1f6df2469166babea3f5491ce9 260 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 10 234 1.0E-95 T 28-03-2018 IPR022488 Polyphosphate kinase-2-related MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 233 814 8.2E-172 T 28-03-2018 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 SUPERFAMILY SSF81665 414 507 6.93E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 SUPERFAMILY SSF81665 278 313 6.93E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 Pfam PF00403 Heavy-metal-associated domain 109 165 3.2E-8 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 515 521 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 SUPERFAMILY SSF56784 512 531 3.53E-56 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 SUPERFAMILY SSF56784 570 812 3.53E-56 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 Pfam PF00702 haloacid dehalogenase-like hydrolase 510 726 1.2E-47 T 28-03-2018 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 Gene3D G3DSA:3.40.50.1000 637 776 2.0E-39 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 Gene3D G3DSA:3.40.1110.10 537 636 5.2E-30 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 SUPERFAMILY SSF55008 103 171 2.62E-15 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 Gene3D G3DSA:3.30.70.100 103 169 5.5E-14 T 28-03-2018 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 SUPERFAMILY SSF81653 320 413 2.48E-27 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 659 669 1.3E-26 T 28-03-2018 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 735 747 1.3E-26 T 28-03-2018 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 637 648 1.3E-26 T 28-03-2018 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 363 377 1.3E-26 T 28-03-2018 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 513 527 1.3E-26 T 28-03-2018 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 712 731 1.3E-26 T 28-03-2018 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 PRINTS PR00943 Copper-transporting ATPase signature 496 511 1.2E-11 T 28-03-2018 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 PRINTS PR00943 Copper-transporting ATPase signature 436 450 1.2E-11 T 28-03-2018 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 PRINTS PR00943 Copper-transporting ATPase signature 236 255 1.2E-11 T 28-03-2018 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 PRINTS PR00943 Copper-transporting ATPase signature 302 320 1.2E-11 T 28-03-2018 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 PRINTS PR00943 Copper-transporting ATPase signature 689 706 1.2E-11 T 28-03-2018 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 PRINTS PR00943 Copper-transporting ATPase signature 147 167 1.2E-11 T 28-03-2018 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 Gene3D G3DSA:1.20.1110.10 276 536 2.4E-46 T 28-03-2018 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 ProSitePatterns PS01047 Heavy-metal-associated domain. 111 140 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 Pfam PF00122 E1-E2 ATPase 313 493 2.8E-53 T 28-03-2018 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 285 800 2.0E-86 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS07410 3b13e992d750813f6f95698da53ba045 816 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 251 814 9.3E-183 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MKLM6_RS18340 4dd6fd49d0c044ce13592d70d54cb6c8 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 363 381 2.4E-96 T 28-03-2018 MKLM6_RS18340 4dd6fd49d0c044ce13592d70d54cb6c8 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 147 172 2.4E-96 T 28-03-2018 MKLM6_RS18340 4dd6fd49d0c044ce13592d70d54cb6c8 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 308 330 2.4E-96 T 28-03-2018 MKLM6_RS18340 4dd6fd49d0c044ce13592d70d54cb6c8 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 265 284 2.4E-96 T 28-03-2018 MKLM6_RS18340 4dd6fd49d0c044ce13592d70d54cb6c8 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 108 131 2.4E-96 T 28-03-2018 MKLM6_RS18340 4dd6fd49d0c044ce13592d70d54cb6c8 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 67 87 2.4E-96 T 28-03-2018 MKLM6_RS18340 4dd6fd49d0c044ce13592d70d54cb6c8 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 15 33 2.4E-96 T 28-03-2018 MKLM6_RS18340 4dd6fd49d0c044ce13592d70d54cb6c8 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 173 196 2.4E-96 T 28-03-2018 MKLM6_RS18340 4dd6fd49d0c044ce13592d70d54cb6c8 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 395 413 2.4E-96 T 28-03-2018 MKLM6_RS18340 4dd6fd49d0c044ce13592d70d54cb6c8 434 Gene3D G3DSA:1.10.3370.10 3 432 5.4E-158 T 28-03-2018 MKLM6_RS18340 4dd6fd49d0c044ce13592d70d54cb6c8 434 Pfam PF00344 SecY translocase 68 409 1.0E-114 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MKLM6_RS18340 4dd6fd49d0c044ce13592d70d54cb6c8 434 ProSitePatterns PS00755 Protein secY signature 1. 68 87 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MKLM6_RS18340 4dd6fd49d0c044ce13592d70d54cb6c8 434 PIRSF PIRSF004557 2 434 5.5E-122 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MKLM6_RS18340 4dd6fd49d0c044ce13592d70d54cb6c8 434 Hamap MF_01465 Protein translocase subunit SecY [secY]. 2 426 29.524 T 28-03-2018 IPR026593 Protein translocase subunit SecY MKLM6_RS18340 4dd6fd49d0c044ce13592d70d54cb6c8 434 ProSitePatterns PS00756 Protein secY signature 2. 166 183 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MKLM6_RS18340 4dd6fd49d0c044ce13592d70d54cb6c8 434 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 12 422 6.2E-130 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MKLM6_RS18340 4dd6fd49d0c044ce13592d70d54cb6c8 434 SUPERFAMILY SSF103491 6 417 1.44E-128 T 28-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MKLM6_RS19425 6e602b5c48e90dbbd31cfa3637bcb03b 436 Gene3D G3DSA:2.40.50.140 375 436 5.3E-20 T 28-03-2018 MKLM6_RS19425 6e602b5c48e90dbbd31cfa3637bcb03b 436 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 4 435 60.363 T 28-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 MKLM6_RS19425 6e602b5c48e90dbbd31cfa3637bcb03b 436 SUPERFAMILY SSF102114 118 366 2.35E-50 T 28-03-2018 MKLM6_RS19425 6e602b5c48e90dbbd31cfa3637bcb03b 436 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 139 159 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 MKLM6_RS19425 6e602b5c48e90dbbd31cfa3637bcb03b 436 Gene3D G3DSA:3.80.30.20 132 374 2.6E-45 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe MKLM6_RS19425 6e602b5c48e90dbbd31cfa3637bcb03b 436 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 5 433 7.1E-102 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 MKLM6_RS19425 6e602b5c48e90dbbd31cfa3637bcb03b 436 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 5 432 1.3E-174 T 28-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 MKLM6_RS19425 6e602b5c48e90dbbd31cfa3637bcb03b 436 Pfam PF04055 Radical SAM superfamily 141 318 9.8E-28 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS19425 6e602b5c48e90dbbd31cfa3637bcb03b 436 Pfam PF00919 Uncharacterized protein family UPF0004 5 93 2.6E-20 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 MKLM6_RS19425 6e602b5c48e90dbbd31cfa3637bcb03b 436 SMART SM00729 135 360 1.4E-50 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MKLM6_RS18270 db0630b27e1eb66c2526ed1eb0d35409 302 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 29 257 1.5E-65 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 MKLM6_RS18270 db0630b27e1eb66c2526ed1eb0d35409 302 Gene3D G3DSA:3.40.50.620 2 300 1.3E-41 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS18270 db0630b27e1eb66c2526ed1eb0d35409 302 Hamap MF_00064 Sulfate adenylyltransferase subunit 2 [cysD]. 4 302 58.53 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MKLM6_RS18270 db0630b27e1eb66c2526ed1eb0d35409 302 SUPERFAMILY SSF52402 3 210 4.44E-76 T 28-03-2018 MKLM6_RS18270 db0630b27e1eb66c2526ed1eb0d35409 302 PIRSF PIRSF002936 1 302 5.0E-159 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MKLM6_RS18270 db0630b27e1eb66c2526ed1eb0d35409 302 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 9 302 3.4E-162 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 SUPERFAMILY SSF50249 190 277 2.46E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 PIRSF PIRSF002111 1 534 4.0E-213 T 28-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 3 520 1.5E-212 T 28-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 SUPERFAMILY SSF50249 103 185 2.42E-11 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 SUPERFAMILY SSF50249 3 112 2.73E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 SMART SM00316 275 347 2.8E-26 T 28-03-2018 IPR022967 RNA-binding domain, S1 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 SMART SM00316 103 171 2.0E-4 T 28-03-2018 IPR022967 RNA-binding domain, S1 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 SMART SM00316 19 87 0.079 T 28-03-2018 IPR022967 RNA-binding domain, S1 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 SMART SM00316 362 434 4.5E-21 T 28-03-2018 IPR022967 RNA-binding domain, S1 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 SMART SM00316 449 520 8.0E-22 T 28-03-2018 IPR022967 RNA-binding domain, S1 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 SMART SM00316 190 260 1.7E-26 T 28-03-2018 IPR022967 RNA-binding domain, S1 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 Gene3D G3DSA:2.40.50.140 451 545 1.2E-20 T 28-03-2018 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 SUPERFAMILY SSF50249 429 535 7.86E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 Pfam PF00575 S1 RNA binding domain 103 171 6.2E-6 T 28-03-2018 IPR003029 S1 domain GO:0003676 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 Pfam PF00575 S1 RNA binding domain 361 434 5.7E-20 T 28-03-2018 IPR003029 S1 domain GO:0003676 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 Pfam PF00575 S1 RNA binding domain 275 347 2.9E-20 T 28-03-2018 IPR003029 S1 domain GO:0003676 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 Pfam PF00575 S1 RNA binding domain 448 520 1.3E-16 T 28-03-2018 IPR003029 S1 domain GO:0003676 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 Pfam PF00575 S1 RNA binding domain 190 260 6.6E-22 T 28-03-2018 IPR003029 S1 domain GO:0003676 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 Gene3D G3DSA:2.40.50.140 1 90 9.4E-5 T 28-03-2018 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 SUPERFAMILY SSF50249 346 440 4.5E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 SUPERFAMILY SSF50249 255 359 7.15E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 Gene3D G3DSA:2.40.50.140 183 266 2.1E-25 T 28-03-2018 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 Gene3D G3DSA:2.40.50.140 96 177 9.0E-6 T 28-03-2018 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 PRINTS PR00681 Ribosomal protein S1 signature 21 39 3.5E-81 T 28-03-2018 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 PRINTS PR00681 Ribosomal protein S1 signature 290 309 3.5E-81 T 28-03-2018 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 PRINTS PR00681 Ribosomal protein S1 signature 108 124 3.5E-81 T 28-03-2018 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 PRINTS PR00681 Ribosomal protein S1 signature 39 53 3.5E-81 T 28-03-2018 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 PRINTS PR00681 Ribosomal protein S1 signature 212 233 3.5E-81 T 28-03-2018 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 PRINTS PR00681 Ribosomal protein S1 signature 84 103 3.5E-81 T 28-03-2018 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 PRINTS PR00681 Ribosomal protein S1 signature 155 175 3.5E-81 T 28-03-2018 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 PRINTS PR00681 Ribosomal protein S1 signature 126 143 3.5E-81 T 28-03-2018 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 PRINTS PR00681 Ribosomal protein S1 signature 330 348 3.5E-81 T 28-03-2018 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 Gene3D G3DSA:2.40.50.140 361 435 4.6E-21 T 28-03-2018 MKLM6_RS10820 ec13661d85289328a0128dcad0a56789 553 Gene3D G3DSA:2.40.50.140 274 348 8.4E-27 T 28-03-2018 MKLM6_RS10740 c7c83699375ba4de6bafb5597455f74b 1295 Gene3D G3DSA:3.40.50.880 1043 1294 7.8E-29 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS10740 c7c83699375ba4de6bafb5597455f74b 1295 SUPERFAMILY SSF56042 436 661 3.74E-48 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MKLM6_RS10740 c7c83699375ba4de6bafb5597455f74b 1295 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 5 1294 0.0 T 28-03-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MKLM6_RS10740 c7c83699375ba4de6bafb5597455f74b 1295 SUPERFAMILY SSF109736 160 225 8.11E-22 T 28-03-2018 MKLM6_RS10740 c7c83699375ba4de6bafb5597455f74b 1295 Gene3D G3DSA:3.30.1330.10 188 223 0.0012 T 28-03-2018 IPR016188 PurM-like, N-terminal domain MKLM6_RS10740 c7c83699375ba4de6bafb5597455f74b 1295 Gene3D G3DSA:3.30.1330.10 224 428 9.5E-46 T 28-03-2018 IPR016188 PurM-like, N-terminal domain MKLM6_RS10740 c7c83699375ba4de6bafb5597455f74b 1295 Gene3D G3DSA:3.30.1330.10 618 819 3.8E-18 T 28-03-2018 IPR016188 PurM-like, N-terminal domain MKLM6_RS10740 c7c83699375ba4de6bafb5597455f74b 1295 Pfam PF02769 AIR synthase related protein, C-terminal domain 831 972 1.1E-14 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MKLM6_RS10740 c7c83699375ba4de6bafb5597455f74b 1295 Pfam PF02769 AIR synthase related protein, C-terminal domain 438 593 6.5E-26 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MKLM6_RS10740 c7c83699375ba4de6bafb5597455f74b 1295 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1044 1294 1.7E-102 T 28-03-2018 MKLM6_RS10740 c7c83699375ba4de6bafb5597455f74b 1295 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 1 1295 20.993 T 28-03-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MKLM6_RS10740 c7c83699375ba4de6bafb5597455f74b 1295 SMART SM01211 1044 1294 3.3E-146 T 28-03-2018 MKLM6_RS10740 c7c83699375ba4de6bafb5597455f74b 1295 SUPERFAMILY SSF56042 823 1037 2.24E-58 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MKLM6_RS10740 c7c83699375ba4de6bafb5597455f74b 1295 SUPERFAMILY SSF55326 226 428 6.28E-56 T 28-03-2018 IPR016188 PurM-like, N-terminal domain MKLM6_RS10740 c7c83699375ba4de6bafb5597455f74b 1295 SUPERFAMILY SSF55326 628 822 2.12E-64 T 28-03-2018 IPR016188 PurM-like, N-terminal domain MKLM6_RS10740 c7c83699375ba4de6bafb5597455f74b 1295 SUPERFAMILY SSF82697 1 152 2.41E-41 T 28-03-2018 MKLM6_RS10740 c7c83699375ba4de6bafb5597455f74b 1295 SUPERFAMILY SSF52317 1042 1294 5.63E-92 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS10740 c7c83699375ba4de6bafb5597455f74b 1295 Gene3D G3DSA:3.90.650.10 432 613 5.7E-27 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MKLM6_RS10740 c7c83699375ba4de6bafb5597455f74b 1295 Gene3D G3DSA:3.90.650.10 824 1000 8.3E-34 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MKLM6_RS09825 c708486872ec3bf58c127c9746d2bf60 415 Gene3D G3DSA:2.40.50.100 52 83 0.069 T 28-03-2018 MKLM6_RS09825 c708486872ec3bf58c127c9746d2bf60 415 Gene3D G3DSA:2.40.50.100 84 142 5.1E-13 T 28-03-2018 MKLM6_RS09825 c708486872ec3bf58c127c9746d2bf60 415 SUPERFAMILY SSF51230 68 107 2.98E-5 T 28-03-2018 IPR011053 Single hybrid motif MKLM6_RS09825 c708486872ec3bf58c127c9746d2bf60 415 Pfam PF13437 HlyD family secretion protein 264 386 2.7E-11 T 28-03-2018 MKLM6_RS09825 c708486872ec3bf58c127c9746d2bf60 415 Pfam PF13533 Biotin-lipoyl like 70 114 5.8E-7 T 28-03-2018 MKLM6_RS09825 c708486872ec3bf58c127c9746d2bf60 415 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 276 297 1.4E-17 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MKLM6_RS09825 c708486872ec3bf58c127c9746d2bf60 415 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 309 333 1.4E-17 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MKLM6_RS09825 c708486872ec3bf58c127c9746d2bf60 415 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 383 398 1.4E-17 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MKLM6_RS09825 c708486872ec3bf58c127c9746d2bf60 415 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 398 415 1.4E-17 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MKLM6_RS09825 c708486872ec3bf58c127c9746d2bf60 415 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 80 100 1.4E-17 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MKLM6_RS09825 c708486872ec3bf58c127c9746d2bf60 415 Gene3D G3DSA:1.20.5.320 206 267 0.029 T 28-03-2018 MKLM6_RS09825 c708486872ec3bf58c127c9746d2bf60 415 Gene3D G3DSA:2.40.50.100 268 343 0.0079 T 28-03-2018 MKLM6_RS11365 11b9cde8bbd1274f4e4d71724fe185a8 167 SUPERFAMILY SSF54523 25 146 6.83E-8 T 28-03-2018 MKLM6_RS11365 11b9cde8bbd1274f4e4d71724fe185a8 167 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 23 43 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS11365 11b9cde8bbd1274f4e4d71724fe185a8 167 Pfam PF12019 Type II transport protein GspH 61 155 2.4E-6 T 28-03-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 MKLM6_RS11365 11b9cde8bbd1274f4e4d71724fe185a8 167 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 23 43 2.7E-4 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS11365 11b9cde8bbd1274f4e4d71724fe185a8 167 TIGRFAM TIGR01708 typeII_sec_gspH: type II secretion system protein H 23 157 5.1E-15 T 28-03-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 MKLM6_RS11365 11b9cde8bbd1274f4e4d71724fe185a8 167 Pfam PF07963 Prokaryotic N-terminal methylation motif 19 44 1.5E-5 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS11365 11b9cde8bbd1274f4e4d71724fe185a8 167 Gene3D G3DSA:3.55.40.10 55 167 3.7E-6 T 28-03-2018 MKLM6_RS06995 b72d18698dc16cfb0b6d5af783febb69 153 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 153 70.292 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MKLM6_RS06995 b72d18698dc16cfb0b6d5af783febb69 153 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 4 142 1.1E-59 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MKLM6_RS06995 b72d18698dc16cfb0b6d5af783febb69 153 PIRSF PIRSF001399 1 147 4.2E-61 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MKLM6_RS06995 b72d18698dc16cfb0b6d5af783febb69 153 SUPERFAMILY SSF52304 3 148 1.44E-62 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MKLM6_RS06995 b72d18698dc16cfb0b6d5af783febb69 153 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 4 140 2.0E-54 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MKLM6_RS06995 b72d18698dc16cfb0b6d5af783febb69 153 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 28-03-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MKLM6_RS06995 b72d18698dc16cfb0b6d5af783febb69 153 Pfam PF01220 Dehydroquinase class II 4 140 2.3E-60 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MKLM6_RS06995 b72d18698dc16cfb0b6d5af783febb69 153 Gene3D G3DSA:3.40.50.9100 1 147 1.9E-66 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MKLM6_RS02180 7424b931cccecd3d9189be1363839d86 500 SMART SM00283 266 499 2.4E-60 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS02180 7424b931cccecd3d9189be1363839d86 500 Gene3D G3DSA:1.20.120.30 21 182 1.2E-18 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain MKLM6_RS02180 7424b931cccecd3d9189be1363839d86 500 Pfam PF12729 Four helix bundle sensory module for signal transduction 4 181 2.7E-27 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain MKLM6_RS02180 7424b931cccecd3d9189be1363839d86 500 SUPERFAMILY SSF58104 234 500 1.83E-56 T 28-03-2018 MKLM6_RS02180 7424b931cccecd3d9189be1363839d86 500 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 485 1.6E-29 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS02180 7424b931cccecd3d9189be1363839d86 500 Gene3D G3DSA:1.10.287.950 325 500 2.2E-42 T 28-03-2018 MKLM6_RS02180 7424b931cccecd3d9189be1363839d86 500 Gene3D G3DSA:1.10.287.1060 237 324 0.063 T 28-03-2018 MKLM6_RS16425 84ae857431cefdd764cbdbcb7afae7db 264 PRINTS PR01959 SuhB family inositol monophosphatase signature 102 121 9.2E-27 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 MKLM6_RS16425 84ae857431cefdd764cbdbcb7afae7db 264 PRINTS PR01959 SuhB family inositol monophosphatase signature 17 39 9.2E-27 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 MKLM6_RS16425 84ae857431cefdd764cbdbcb7afae7db 264 PRINTS PR01959 SuhB family inositol monophosphatase signature 196 208 9.2E-27 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 MKLM6_RS16425 84ae857431cefdd764cbdbcb7afae7db 264 PRINTS PR01959 SuhB family inositol monophosphatase signature 154 180 9.2E-27 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 MKLM6_RS16425 84ae857431cefdd764cbdbcb7afae7db 264 Gene3D G3DSA:3.40.190.80 144 264 1.6E-35 T 28-03-2018 MKLM6_RS16425 84ae857431cefdd764cbdbcb7afae7db 264 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 209 223 - T 28-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 MKLM6_RS16425 84ae857431cefdd764cbdbcb7afae7db 264 Gene3D G3DSA:3.30.540.10 1 143 1.5E-47 T 28-03-2018 MKLM6_RS16425 84ae857431cefdd764cbdbcb7afae7db 264 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 79 92 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site MKLM6_RS16425 84ae857431cefdd764cbdbcb7afae7db 264 Pfam PF00459 Inositol monophosphatase family 2 254 4.6E-70 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MKLM6_RS16425 84ae857431cefdd764cbdbcb7afae7db 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 4.6E-58 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MKLM6_RS16425 84ae857431cefdd764cbdbcb7afae7db 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 206 230 4.6E-58 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MKLM6_RS16425 84ae857431cefdd764cbdbcb7afae7db 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 4.6E-58 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MKLM6_RS16425 84ae857431cefdd764cbdbcb7afae7db 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 175 196 4.6E-58 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MKLM6_RS16425 84ae857431cefdd764cbdbcb7afae7db 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 128 151 4.6E-58 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MKLM6_RS16425 84ae857431cefdd764cbdbcb7afae7db 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 79 95 4.6E-58 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MKLM6_RS16425 84ae857431cefdd764cbdbcb7afae7db 264 SUPERFAMILY SSF56655 1 258 3.01E-86 T 28-03-2018 MKLM6_RS13940 8ac856d4276a50c29a349a4a654f1971 223 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 9 208 3.3E-52 T 28-03-2018 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 MKLM6_RS13940 8ac856d4276a50c29a349a4a654f1971 223 Gene3D G3DSA:1.10.150.240 21 76 5.1E-12 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 MKLM6_RS13940 8ac856d4276a50c29a349a4a654f1971 223 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 63 185 3.3E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MKLM6_RS13940 8ac856d4276a50c29a349a4a654f1971 223 SUPERFAMILY SSF56784 6 217 1.27E-55 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS13940 8ac856d4276a50c29a349a4a654f1971 223 Gene3D G3DSA:3.40.50.1000 77 223 1.3E-33 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS13940 8ac856d4276a50c29a349a4a654f1971 223 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 87 180 8.6E-11 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MKLM6_RS13940 8ac856d4276a50c29a349a4a654f1971 223 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 186 4.2E-37 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS19100 59b1b9ae015737b3f668edbf1c6198bd 139 Pfam PF06146 Phosphate-starvation-inducible E 59 127 6.0E-15 T 28-03-2018 IPR020948 Phosphate-starvation-induced PsiE-like MKLM6_RS19100 59b1b9ae015737b3f668edbf1c6198bd 139 PIRSF PIRSF029598 4 138 1.8E-32 T 28-03-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 MKLM6_RS07875 91dac4ebc63b3c7a9df0beb19123213b 395 SMART SM00028 104 137 3.9 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS07875 91dac4ebc63b3c7a9df0beb19123213b 395 SMART SM00028 210 243 26.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS07875 91dac4ebc63b3c7a9df0beb19123213b 395 Gene3D G3DSA:1.25.40.10 103 194 6.6E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS07875 91dac4ebc63b3c7a9df0beb19123213b 395 SUPERFAMILY SSF81901 104 277 3.92E-9 T 28-03-2018 MKLM6_RS07875 91dac4ebc63b3c7a9df0beb19123213b 395 Gene3D G3DSA:1.25.40.10 195 377 3.4E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS21015 633cc2bc216e8895f729ca0dc94068a5 407 Pfam PF03929 PepSY-associated TM region 33 398 2.1E-63 T 28-03-2018 IPR005625 PepSY-associated TM protein MKLM6_RS21015 633cc2bc216e8895f729ca0dc94068a5 407 Gene3D G3DSA:1.20.950.20 9 104 0.054 T 28-03-2018 MKLM6_RS21015 633cc2bc216e8895f729ca0dc94068a5 407 Gene3D G3DSA:1.20.950.20 180 314 0.0075 T 28-03-2018 MKLM6_RS18975 2ab717922fb6fbe3670e8d755203ce55 709 SMART SM00052 435 681 4.6E-98 T 28-03-2018 IPR001633 EAL domain MKLM6_RS18975 2ab717922fb6fbe3670e8d755203ce55 709 Pfam PF00990 Diguanylate cyclase, GGDEF domain 264 421 2.9E-49 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS18975 2ab717922fb6fbe3670e8d755203ce55 709 SUPERFAMILY SSF55785 147 250 2.79E-29 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18975 2ab717922fb6fbe3670e8d755203ce55 709 SUPERFAMILY SSF141868 442 692 4.18E-82 T 28-03-2018 IPR001633 EAL domain MKLM6_RS18975 2ab717922fb6fbe3670e8d755203ce55 709 Pfam PF13426 PAS domain 150 251 2.4E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18975 2ab717922fb6fbe3670e8d755203ce55 709 Gene3D G3DSA:3.30.70.270 257 426 2.5E-62 T 28-03-2018 MKLM6_RS18975 2ab717922fb6fbe3670e8d755203ce55 709 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 260 424 8.3E-41 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS18975 2ab717922fb6fbe3670e8d755203ce55 709 SMART SM00091 139 205 1.6E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18975 2ab717922fb6fbe3670e8d755203ce55 709 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 143 258 5.7E-20 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18975 2ab717922fb6fbe3670e8d755203ce55 709 SMART SM00448 6 118 4.5E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS18975 2ab717922fb6fbe3670e8d755203ce55 709 Gene3D G3DSA:3.30.450.20 136 256 4.7E-26 T 28-03-2018 MKLM6_RS18975 2ab717922fb6fbe3670e8d755203ce55 709 Gene3D G3DSA:3.40.50.2300 3 135 1.7E-35 T 28-03-2018 MKLM6_RS18975 2ab717922fb6fbe3670e8d755203ce55 709 SMART SM00267 253 425 2.8E-62 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS18975 2ab717922fb6fbe3670e8d755203ce55 709 SUPERFAMILY SSF55073 269 427 2.51E-51 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS18975 2ab717922fb6fbe3670e8d755203ce55 709 Pfam PF00072 Response regulator receiver domain 8 112 3.2E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS18975 2ab717922fb6fbe3670e8d755203ce55 709 Gene3D G3DSA:3.20.20.450 427 695 1.4E-86 T 28-03-2018 IPR001633 EAL domain MKLM6_RS18975 2ab717922fb6fbe3670e8d755203ce55 709 SMART SM00086 211 253 1.7E-6 T 28-03-2018 IPR001610 PAC motif MKLM6_RS18975 2ab717922fb6fbe3670e8d755203ce55 709 SUPERFAMILY SSF52172 5 151 6.4E-38 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS18975 2ab717922fb6fbe3670e8d755203ce55 709 Pfam PF00563 EAL domain 444 676 2.6E-68 T 28-03-2018 IPR001633 EAL domain MKLM6_RS03220 a3d411e67679e7f029e299bf5c993883 338 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 9 132 8.9E-22 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MKLM6_RS03220 a3d411e67679e7f029e299bf5c993883 338 SUPERFAMILY SSF55347 137 305 4.41E-40 T 28-03-2018 MKLM6_RS03220 a3d411e67679e7f029e299bf5c993883 338 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 145 215 1.5E-5 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 MKLM6_RS03220 a3d411e67679e7f029e299bf5c993883 338 Gene3D G3DSA:3.30.360.10 145 338 1.1E-40 T 28-03-2018 MKLM6_RS03220 a3d411e67679e7f029e299bf5c993883 338 SUPERFAMILY SSF51735 7 164 2.25E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS03220 a3d411e67679e7f029e299bf5c993883 338 Gene3D G3DSA:3.40.50.720 2 144 2.6E-37 T 28-03-2018 MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 Gene3D G3DSA:3.40.190.10 27 141 1.0E-10 T 28-03-2018 MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 Gene3D G3DSA:3.20.20.450 1145 1404 7.6E-84 T 28-03-2018 IPR001633 EAL domain MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 SUPERFAMILY SSF53850 27 256 4.61E-25 T 28-03-2018 MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 Pfam PF13188 PAS domain 608 664 0.0055 T 28-03-2018 IPR000014 PAS domain MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 Gene3D G3DSA:3.40.190.10 326 435 2.3E-18 T 28-03-2018 MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 Pfam PF00990 Diguanylate cyclase, GGDEF domain 978 1135 2.2E-49 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 SUPERFAMILY SSF55073 983 1140 3.3E-49 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 SUPERFAMILY SSF141868 1162 1415 5.23E-79 T 28-03-2018 IPR001633 EAL domain MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 Gene3D G3DSA:3.40.190.10 436 521 3.3E-14 T 28-03-2018 MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 Gene3D G3DSA:3.30.450.20 589 710 8.1E-15 T 28-03-2018 MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 Pfam PF13426 PAS domain 864 966 3.9E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 SMART SM00267 967 1139 1.3E-67 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 Pfam PF09084 NMT1/THI5 like 40 248 2.5E-45 T 28-03-2018 IPR015168 SsuA/THI5-like MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 634 725 1.7E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 727 852 2.7E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 858 974 1.1E-19 T 28-03-2018 IPR000014 PAS domain MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 Gene3D G3DSA:3.30.450.20 711 851 3.3E-33 T 28-03-2018 MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 SMART SM00091 730 797 5.3 T 28-03-2018 IPR000014 PAS domain MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 SMART SM00091 853 920 2.7E-4 T 28-03-2018 IPR000014 PAS domain MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 SMART SM00091 604 678 9.0 T 28-03-2018 IPR000014 PAS domain MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 Pfam PF00563 EAL domain 1162 1397 6.4E-68 T 28-03-2018 IPR001633 EAL domain MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 SUPERFAMILY SSF53850 334 561 5.04E-49 T 28-03-2018 MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 974 1138 1.9E-40 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 Gene3D G3DSA:3.40.50.10600 852 965 8.9E-26 T 28-03-2018 MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 SMART SM00052 1155 1402 3.9E-91 T 28-03-2018 IPR001633 EAL domain MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 SMART SM00086 925 967 1.3E-5 T 28-03-2018 IPR001610 PAC motif MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 SMART SM00086 803 845 1.3E-9 T 28-03-2018 IPR001610 PAC motif MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 342 559 1.0E-38 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 SMART SM00062 341 561 9.8E-36 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 SUPERFAMILY SSF55785 862 964 4.71E-28 T 28-03-2018 IPR000014 PAS domain MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 Gene3D G3DSA:3.40.190.10 142 313 9.2E-18 T 28-03-2018 MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 SUPERFAMILY SSF55785 741 848 7.5E-21 T 28-03-2018 IPR000014 PAS domain MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 Gene3D G3DSA:3.30.70.270 966 1140 2.3E-62 T 28-03-2018 MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 Pfam PF08447 PAS fold 754 839 4.0E-16 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS01960 f2d65c3506c671940d0bd39d6ab507a0 1542 SUPERFAMILY SSF55785 632 727 5.58E-11 T 28-03-2018 IPR000014 PAS domain MKLM6_RS12395 0d4335b2ef75af2b493ffacdd8965371 723 SMART SM00563 31 141 5.0E-24 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MKLM6_RS12395 0d4335b2ef75af2b493ffacdd8965371 723 Gene3D G3DSA:3.40.1130.10 1 209 2.1E-27 T 28-03-2018 MKLM6_RS12395 0d4335b2ef75af2b493ffacdd8965371 723 Pfam PF01553 Acyltransferase 15 138 1.4E-16 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MKLM6_RS12395 0d4335b2ef75af2b493ffacdd8965371 723 SUPERFAMILY SSF56801 200 713 2.75E-93 T 28-03-2018 MKLM6_RS12395 0d4335b2ef75af2b493ffacdd8965371 723 SUPERFAMILY SSF69593 6 180 9.02E-23 T 28-03-2018 MKLM6_RS12395 0d4335b2ef75af2b493ffacdd8965371 723 Gene3D G3DSA:3.30.300.30 617 721 1.9E-8 T 28-03-2018 MKLM6_RS12395 0d4335b2ef75af2b493ffacdd8965371 723 Pfam PF00501 AMP-binding enzyme 231 620 1.9E-64 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MKLM6_RS12395 0d4335b2ef75af2b493ffacdd8965371 723 Gene3D G3DSA:3.40.50.980 381 529 4.3E-43 T 28-03-2018 MKLM6_RS12395 0d4335b2ef75af2b493ffacdd8965371 723 Gene3D G3DSA:2.30.38.10 530 613 1.7E-10 T 28-03-2018 MKLM6_RS12395 0d4335b2ef75af2b493ffacdd8965371 723 Gene3D G3DSA:3.40.50.980 210 380 6.3E-21 T 28-03-2018 MKLM6_RS12395 0d4335b2ef75af2b493ffacdd8965371 723 ProSitePatterns PS00455 Putative AMP-binding domain signature. 375 386 - T 28-03-2018 IPR020845 AMP-binding, conserved site MKLM6_RS17035 57c540da5e9658a9be72e2dd1422dea4 94 Pfam PF12838 4Fe-4S dicluster domain 8 57 3.4E-7 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MKLM6_RS17035 57c540da5e9658a9be72e2dd1422dea4 94 Gene3D G3DSA:3.30.70.20 1 22 0.0034 T 28-03-2018 MKLM6_RS17035 57c540da5e9658a9be72e2dd1422dea4 94 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MKLM6_RS17035 57c540da5e9658a9be72e2dd1422dea4 94 SUPERFAMILY SSF54862 6 62 8.38E-13 T 28-03-2018 MKLM6_RS17035 57c540da5e9658a9be72e2dd1422dea4 94 Gene3D G3DSA:3.30.70.20 23 67 1.4E-5 T 28-03-2018 MKLM6_RS05345 cf63372076e6d3cfac40107d30cc3e62 972 Pfam PF02347 Glycine cleavage system P-protein 18 442 7.9E-179 T 28-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MKLM6_RS05345 cf63372076e6d3cfac40107d30cc3e62 972 Pfam PF02347 Glycine cleavage system P-protein 453 735 8.3E-13 T 28-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MKLM6_RS05345 cf63372076e6d3cfac40107d30cc3e62 972 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 19 956 0.0 T 28-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MKLM6_RS05345 cf63372076e6d3cfac40107d30cc3e62 972 SUPERFAMILY SSF53383 19 443 8.49E-106 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS05345 cf63372076e6d3cfac40107d30cc3e62 972 Gene3D G3DSA:3.90.1150.10 344 446 9.5E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS05345 cf63372076e6d3cfac40107d30cc3e62 972 Gene3D G3DSA:3.40.640.10 517 778 3.5E-36 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS05345 cf63372076e6d3cfac40107d30cc3e62 972 Gene3D G3DSA:3.90.1150.10 779 911 1.1E-43 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS05345 cf63372076e6d3cfac40107d30cc3e62 972 SUPERFAMILY SSF53383 935 957 4.17E-99 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS05345 cf63372076e6d3cfac40107d30cc3e62 972 SUPERFAMILY SSF53383 463 893 4.17E-99 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS05345 cf63372076e6d3cfac40107d30cc3e62 972 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 10 962 24.351 T 28-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MKLM6_RS05345 cf63372076e6d3cfac40107d30cc3e62 972 Gene3D G3DSA:3.40.640.10 97 343 8.7E-37 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS20235 c7f47b3506198492b678c597613a66b3 664 Pfam PF05954 Phage late control gene D protein (GPD) 30 340 2.5E-86 T 28-03-2018 MKLM6_RS20235 c7f47b3506198492b678c597613a66b3 664 SUPERFAMILY SSF69255 374 461 3.14E-34 T 28-03-2018 MKLM6_RS20235 c7f47b3506198492b678c597613a66b3 664 SUPERFAMILY SSF69279 198 372 5.27E-37 T 28-03-2018 MKLM6_RS20235 c7f47b3506198492b678c597613a66b3 664 SUPERFAMILY SSF69279 12 194 3.95E-50 T 28-03-2018 MKLM6_RS20235 c7f47b3506198492b678c597613a66b3 664 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 11 532 3.6E-179 T 28-03-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset MKLM6_RS20235 c7f47b3506198492b678c597613a66b3 664 Gene3D G3DSA:2.40.50.230 379 461 2.6E-37 T 28-03-2018 IPR006531 Gp5 N-terminal MKLM6_RS20235 c7f47b3506198492b678c597613a66b3 664 Gene3D G3DSA:3.55.50.10 98 198 6.4E-23 T 28-03-2018 MKLM6_RS20235 c7f47b3506198492b678c597613a66b3 664 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 22 515 4.1E-146 T 28-03-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein MKLM6_RS20235 c7f47b3506198492b678c597613a66b3 664 SUPERFAMILY SSF69349 451 638 6.28E-30 T 28-03-2018 MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 SUPERFAMILY SSF55785 678 785 2.62E-30 T 28-03-2018 IPR000014 PAS domain MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 SMART SM00052 969 1216 3.4E-91 T 28-03-2018 IPR001633 EAL domain MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 Gene3D G3DSA:3.20.20.450 967 1220 1.5E-88 T 28-03-2018 IPR001633 EAL domain MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 Pfam PF03924 CHASE domain 259 438 2.3E-41 T 28-03-2018 IPR006189 CHASE domain MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 SMART SM00091 551 618 55.0 T 28-03-2018 IPR000014 PAS domain MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 SMART SM00091 673 739 7.2E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 Pfam PF13426 PAS domain 684 786 3.1E-17 T 28-03-2018 IPR000014 PAS domain MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 794 958 1.0E-40 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 Pfam PF05231 MASE1 12 211 1.3E-24 T 28-03-2018 IPR007895 MASE1 MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 SMART SM00267 787 959 5.5E-66 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 SMART SM00086 745 787 4.1E-4 T 28-03-2018 IPR001610 PAC motif MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 SMART SM00086 623 665 3.4E-8 T 28-03-2018 IPR001610 PAC motif MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 Gene3D G3DSA:3.30.450.20 521 672 1.2E-25 T 28-03-2018 MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 678 793 5.7E-19 T 28-03-2018 IPR000014 PAS domain MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 547 671 2.4E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 Gene3D G3DSA:3.30.70.270 799 966 3.8E-60 T 28-03-2018 MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 Gene3D G3DSA:3.40.50.10600 673 791 5.2E-28 T 28-03-2018 MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 Pfam PF08448 PAS fold 557 666 3.3E-14 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 Pfam PF00990 Diguanylate cyclase, GGDEF domain 798 955 9.8E-48 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 Pfam PF00563 EAL domain 975 1211 3.4E-68 T 28-03-2018 IPR001633 EAL domain MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 SMART SM01079 256 449 8.5E-47 T 28-03-2018 IPR006189 CHASE domain MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 SUPERFAMILY SSF55073 803 960 1.02E-49 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 SUPERFAMILY SSF55785 536 663 6.98E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS02135 311070902c69b3fc47b408e7424e2ad0 1356 SUPERFAMILY SSF141868 975 1227 1.83E-78 T 28-03-2018 IPR001633 EAL domain MKLM6_RS21330 4f7d68220528c95bcf4b550e322bc5a2 220 PIRSF PIRSF016183 29 206 2.2E-44 T 28-03-2018 IPR006839 Ribosome-associated, YjgA MKLM6_RS21330 4f7d68220528c95bcf4b550e322bc5a2 220 SUPERFAMILY SSF158710 59 201 7.19E-36 T 28-03-2018 IPR023153 PSPTO4464-like domain MKLM6_RS21330 4f7d68220528c95bcf4b550e322bc5a2 220 Gene3D G3DSA:1.10.60.30 58 127 1.4E-12 T 28-03-2018 MKLM6_RS21330 4f7d68220528c95bcf4b550e322bc5a2 220 Gene3D G3DSA:1.10.60.30 133 206 1.5E-23 T 28-03-2018 MKLM6_RS21330 4f7d68220528c95bcf4b550e322bc5a2 220 Pfam PF04751 Protein of unknown function (DUF615) 46 198 9.4E-42 T 28-03-2018 IPR006839 Ribosome-associated, YjgA MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 Gene3D G3DSA:3.30.565.10 597 764 1.3E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 Gene3D G3DSA:1.20.120.160 1047 1172 2.8E-12 T 28-03-2018 MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 SUPERFAMILY SSF55874 591 768 3.54E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 Pfam PF00512 His Kinase A (phospho-acceptor) domain 538 602 7.1E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 SMART SM00387 649 764 3.1E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 Gene3D G3DSA:3.30.450.20 365 511 5.0E-24 T 28-03-2018 MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 SUPERFAMILY SSF103190 234 322 2.43E-21 T 28-03-2018 IPR029151 Periplasmic sensor domain-like MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 Gene3D G3DSA:3.40.50.2300 774 914 1.8E-24 T 28-03-2018 MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 Gene3D G3DSA:1.10.287.130 512 596 1.5E-15 T 28-03-2018 MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 SUPERFAMILY SSF47226 1024 1037 2.62E-16 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 SUPERFAMILY SSF47226 1067 1151 2.62E-16 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 Pfam PF01627 Hpt domain 1087 1163 5.8E-7 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 Pfam PF13188 PAS domain 385 436 2.6E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 PRINTS PR00344 Bacterial sensor protein C-terminal signature 689 703 7.9E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 PRINTS PR00344 Bacterial sensor protein C-terminal signature 707 717 7.9E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 PRINTS PR00344 Bacterial sensor protein C-terminal signature 724 742 7.9E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 PRINTS PR00344 Bacterial sensor protein C-terminal signature 748 761 7.9E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 SUPERFAMILY SSF55785 395 506 1.16E-23 T 28-03-2018 IPR000014 PAS domain MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 SMART SM00091 383 449 4.0E-8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 649 763 1.2E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 SUPERFAMILY SSF103190 60 223 1.1E-42 T 28-03-2018 IPR029151 Periplasmic sensor domain-like MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 381 505 3.8E-21 T 28-03-2018 IPR000014 PAS domain MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 SUPERFAMILY SSF47384 523 603 3.14E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 SUPERFAMILY SSF52172 779 905 1.71E-24 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 Gene3D G3DSA:3.40.50.2300 915 1046 4.3E-38 T 28-03-2018 MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 Gene3D G3DSA:3.30.450.20 232 323 1.5E-26 T 28-03-2018 MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 Pfam PF00072 Response regulator receiver domain 780 899 1.1E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 Pfam PF00072 Response regulator receiver domain 928 1041 5.9E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 SUPERFAMILY SSF52172 925 1047 1.71E-36 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 Gene3D G3DSA:3.30.450.20 90 223 3.2E-37 T 28-03-2018 MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 SMART SM00388 537 602 3.2E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 SMART SM00448 926 1041 3.3E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS06500 6d713ebd17854b81e362f0f1a957943c 1263 SMART SM00448 778 899 3.3E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS09505 3a39dca6fb472a0bb52378e35f6396e5 99 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 3 97 8.5E-49 T 28-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 MKLM6_RS09505 3a39dca6fb472a0bb52378e35f6396e5 99 Pfam PF00216 Bacterial DNA-binding protein 4 92 9.5E-31 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MKLM6_RS09505 3a39dca6fb472a0bb52378e35f6396e5 99 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 49 68 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 MKLM6_RS09505 3a39dca6fb472a0bb52378e35f6396e5 99 Gene3D G3DSA:4.10.520.10 2 99 1.1E-31 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 MKLM6_RS09505 3a39dca6fb472a0bb52378e35f6396e5 99 SMART SM00411 4 93 1.5E-41 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MKLM6_RS09505 3a39dca6fb472a0bb52378e35f6396e5 99 SUPERFAMILY SSF47729 4 93 3.68E-31 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 MKLM6_RS09505 3a39dca6fb472a0bb52378e35f6396e5 99 PRINTS PR01727 Prokaryotic integration host factor signature 43 58 4.2E-16 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MKLM6_RS09505 3a39dca6fb472a0bb52378e35f6396e5 99 PRINTS PR01727 Prokaryotic integration host factor signature 77 91 4.2E-16 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MKLM6_RS09505 3a39dca6fb472a0bb52378e35f6396e5 99 PRINTS PR01727 Prokaryotic integration host factor signature 61 74 4.2E-16 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MKLM6_RS09505 3a39dca6fb472a0bb52378e35f6396e5 99 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 2 98 30.122 T 28-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 MKLM6_RS03170 60fb010912d30799f65505a238910e3e 224 TIGRFAM TIGR00608 radc: DNA repair protein RadC 11 224 1.8E-71 T 28-03-2018 IPR001405 RadC protein MKLM6_RS03170 60fb010912d30799f65505a238910e3e 224 Pfam PF04002 RadC-like JAB domain 104 223 2.2E-42 T 28-03-2018 IPR025657 RadC-like JAB domain MKLM6_RS03170 60fb010912d30799f65505a238910e3e 224 Gene3D G3DSA:1.10.340.30 17 113 0.0013 T 28-03-2018 MKLM6_RS03170 60fb010912d30799f65505a238910e3e 224 SUPERFAMILY SSF47781 17 90 3.48E-9 T 28-03-2018 IPR010994 RuvA domain 2-like MKLM6_RS03170 60fb010912d30799f65505a238910e3e 224 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 173 178 - T 28-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site MKLM6_RS03170 60fb010912d30799f65505a238910e3e 224 Gene3D G3DSA:3.40.140.10 114 224 3.0E-45 T 28-03-2018 MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 SMART SM00052 1017 1265 1.3E-123 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 Gene3D G3DSA:3.30.450.20 724 844 1.1E-14 T 28-03-2018 MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 845 1001 1.1E-22 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 Pfam PF00072 Response regulator receiver domain 1287 1397 1.5E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 Pfam PF00072 Response regulator receiver domain 159 269 1.4E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 Pfam PF00072 Response regulator receiver domain 17 128 3.4E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 Pfam PF08447 PAS fold 327 406 5.1E-16 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 Gene3D G3DSA:3.20.20.450 1015 1275 2.3E-102 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 Pfam PF00990 Diguanylate cyclase, GGDEF domain 847 999 8.1E-31 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 Pfam PF13185 GAF domain 577 712 2.1E-14 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 SMART SM00448 156 269 3.4E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 SMART SM00448 15 128 5.9E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 SMART SM00448 1285 1397 1.3E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 SUPERFAMILY SSF55785 320 414 5.15E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 SUPERFAMILY SSF55073 852 1008 1.26E-32 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 720 841 1.8E-11 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 423 553 1.4E-8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 327 421 3.2E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 Gene3D G3DSA:3.30.450.20 422 566 2.6E-20 T 28-03-2018 MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 SMART SM00267 835 1007 1.3E-31 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 SUPERFAMILY SSF52172 156 310 9.96E-35 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 Pfam PF00563 EAL domain 1023 1260 2.9E-73 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 SUPERFAMILY SSF52172 13 145 5.83E-37 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 SUPERFAMILY SSF141868 1023 1275 5.89E-90 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 Gene3D G3DSA:3.30.70.270 845 1014 7.0E-38 T 28-03-2018 MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 SUPERFAMILY SSF52172 1284 1406 1.32E-28 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 SMART SM00091 294 363 5.8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 SMART SM00091 426 500 82.0 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 SMART SM00091 722 789 0.014 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 Gene3D G3DSA:3.40.50.2300 8 154 1.5E-36 T 28-03-2018 MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 Gene3D G3DSA:3.40.50.2300 1281 1412 1.2E-26 T 28-03-2018 MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 Gene3D G3DSA:3.40.50.2300 155 296 1.9E-31 T 28-03-2018 MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 SUPERFAMILY SSF55781 579 721 7.85E-12 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 SMART SM00065 574 722 0.0056 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 SUPERFAMILY SSF55785 711 818 1.61E-13 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 SUPERFAMILY SSF55785 411 544 8.72E-14 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 Gene3D G3DSA:3.30.450.20 297 421 1.4E-20 T 28-03-2018 MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 Gene3D G3DSA:3.30.450.40 567 723 5.3E-13 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 SMART SM00086 370 414 2.9E-5 T 28-03-2018 IPR001610 PAC motif MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 SMART SM00086 796 835 49.0 T 28-03-2018 IPR001610 PAC motif MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 SMART SM00086 505 546 3.1 T 28-03-2018 IPR001610 PAC motif MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 Pfam PF13426 PAS domain 738 834 6.3E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14270 6bc1db3e51950136f569b17244fbccb3 1412 Pfam PF13426 PAS domain 447 545 0.67 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14780 7242e8584738eb9db1b074f20e6303d3 379 ProSitePatterns PS00636 Nt-dnaJ domain signature. 49 68 - T 28-03-2018 IPR018253 DnaJ domain, conserved site MKLM6_RS14780 7242e8584738eb9db1b074f20e6303d3 379 Gene3D G3DSA:2.60.260.20 256 366 4.1E-25 T 28-03-2018 MKLM6_RS14780 7242e8584738eb9db1b074f20e6303d3 379 SMART SM00271 5 64 4.8E-30 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS14780 7242e8584738eb9db1b074f20e6303d3 379 Pfam PF00684 DnaJ central domain 148 208 3.9E-14 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 MKLM6_RS14780 7242e8584738eb9db1b074f20e6303d3 379 Gene3D G3DSA:2.60.260.20 195 255 6.1E-20 T 28-03-2018 MKLM6_RS14780 7242e8584738eb9db1b074f20e6303d3 379 Pfam PF01556 DnaJ C terminal domain 122 334 1.6E-42 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal MKLM6_RS14780 7242e8584738eb9db1b074f20e6303d3 379 Gene3D G3DSA:1.10.287.110 2 118 3.4E-35 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS14780 7242e8584738eb9db1b074f20e6303d3 379 SUPERFAMILY SSF46565 2 108 6.67E-35 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS14780 7242e8584738eb9db1b074f20e6303d3 379 PRINTS PR00625 DnaJ domain signature 64 83 1.2E-30 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS14780 7242e8584738eb9db1b074f20e6303d3 379 PRINTS PR00625 DnaJ domain signature 8 26 1.2E-30 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS14780 7242e8584738eb9db1b074f20e6303d3 379 PRINTS PR00625 DnaJ domain signature 44 64 1.2E-30 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS14780 7242e8584738eb9db1b074f20e6303d3 379 PRINTS PR00625 DnaJ domain signature 26 41 1.2E-30 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS14780 7242e8584738eb9db1b074f20e6303d3 379 Pfam PF00226 DnaJ domain 6 69 2.6E-27 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS14780 7242e8584738eb9db1b074f20e6303d3 379 SUPERFAMILY SSF49493 116 139 8.37E-22 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MKLM6_RS14780 7242e8584738eb9db1b074f20e6303d3 379 SUPERFAMILY SSF49493 187 268 8.37E-22 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MKLM6_RS14780 7242e8584738eb9db1b074f20e6303d3 379 SUPERFAMILY SSF49493 260 345 8.63E-21 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MKLM6_RS14780 7242e8584738eb9db1b074f20e6303d3 379 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 3 373 40.801 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 MKLM6_RS14780 7242e8584738eb9db1b074f20e6303d3 379 SUPERFAMILY SSF57938 135 212 1.96E-22 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 MKLM6_RS14780 7242e8584738eb9db1b074f20e6303d3 379 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 6 350 5.4E-138 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 MKLM6_RS14780 7242e8584738eb9db1b074f20e6303d3 379 Gene3D G3DSA:2.10.230.10 148 194 1.0E-13 T 28-03-2018 MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 SUPERFAMILY SSF47384 506 588 2.35E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 SMART SM00091 232 299 2.1E-8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 SMART SM00091 370 438 1.3 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 PRINTS PR00344 Bacterial sensor protein C-terminal signature 730 743 3.0E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 PRINTS PR00344 Bacterial sensor protein C-terminal signature 691 701 3.0E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 PRINTS PR00344 Bacterial sensor protein C-terminal signature 673 687 3.0E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 PRINTS PR00344 Bacterial sensor protein C-terminal signature 706 724 3.0E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 Pfam PF00512 His Kinase A (phospho-acceptor) domain 522 587 7.4E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 Pfam PF17152 Periplasmic sensor domain 39 98 8.0E-10 T 28-03-2018 IPR033417 Periplasmic sensor domain CHASE8 MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 Gene3D G3DSA:3.30.450.20 217 371 8.9E-28 T 28-03-2018 MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 SMART SM00448 774 887 3.0E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 Pfam PF00672 HAMP domain 172 221 3.8E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 SUPERFAMILY SSF55874 576 747 1.44E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 313 369 1.7E-8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 376 490 1.9E-14 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 235 291 5.2E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 Pfam PF13426 PAS domain 244 361 2.3E-13 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 Pfam PF13426 PAS domain 389 482 5.2E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 SUPERFAMILY SSF52172 773 901 5.12E-32 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 SMART SM00387 634 746 1.4E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 SMART SM00388 521 587 2.3E-22 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 SUPERFAMILY SSF55785 244 370 1.41E-21 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 Gene3D G3DSA:3.30.565.10 582 746 2.7E-50 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 Gene3D G3DSA:1.10.287.130 511 581 6.8E-20 T 28-03-2018 MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 SUPERFAMILY SSF55785 389 491 4.04E-19 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 Gene3D G3DSA:3.30.450.20 372 501 1.7E-18 T 28-03-2018 MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 SMART SM00086 320 362 2.7E-8 T 28-03-2018 IPR001610 PAC motif MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 SMART SM00086 443 483 50.0 T 28-03-2018 IPR001610 PAC motif MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 Gene3D G3DSA:3.40.50.2300 766 925 9.1E-34 T 28-03-2018 MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 Pfam PF00072 Response regulator receiver domain 776 885 1.1E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 SUPERFAMILY SSF158472 172 221 4.45E-7 T 28-03-2018 MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 SMART SM00304 172 225 1.5E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS03470 43dc4f1155d3e06c9a50b7eb4e705838 978 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 634 745 2.6E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS18175 051410654171c5e78ff4dd26dc59ba41 496 SUPERFAMILY SSF51735 3 191 3.09E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS18175 051410654171c5e78ff4dd26dc59ba41 496 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 5 488 80.281 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MKLM6_RS18175 051410654171c5e78ff4dd26dc59ba41 496 Gene3D G3DSA:3.30.360.10 190 489 4.1E-124 T 28-03-2018 MKLM6_RS18175 051410654171c5e78ff4dd26dc59ba41 496 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 9 188 1.4E-56 T 28-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MKLM6_RS18175 051410654171c5e78ff4dd26dc59ba41 496 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 144 157 3.7E-46 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MKLM6_RS18175 051410654171c5e78ff4dd26dc59ba41 496 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 168 196 3.7E-46 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MKLM6_RS18175 051410654171c5e78ff4dd26dc59ba41 496 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 220 237 3.7E-46 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MKLM6_RS18175 051410654171c5e78ff4dd26dc59ba41 496 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 238 254 3.7E-46 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MKLM6_RS18175 051410654171c5e78ff4dd26dc59ba41 496 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 329 355 3.7E-46 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MKLM6_RS18175 051410654171c5e78ff4dd26dc59ba41 496 PIRSF PIRSF000110 1 490 9.4E-177 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MKLM6_RS18175 051410654171c5e78ff4dd26dc59ba41 496 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 190 487 7.2E-116 T 28-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MKLM6_RS18175 051410654171c5e78ff4dd26dc59ba41 496 Gene3D G3DSA:3.40.50.720 3 189 8.4E-61 T 28-03-2018 MKLM6_RS18175 051410654171c5e78ff4dd26dc59ba41 496 SUPERFAMILY SSF55347 178 487 9.81E-114 T 28-03-2018 MKLM6_RS18175 051410654171c5e78ff4dd26dc59ba41 496 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 5 488 3.3E-180 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MKLM6_RS01140 607b4092c8dbbad7bec9d977f977833d 139 PIRSF PIRSF004681 1 139 6.6E-43 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 MKLM6_RS01140 607b4092c8dbbad7bec9d977f977833d 139 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 9 139 7.0E-41 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 MKLM6_RS01140 607b4092c8dbbad7bec9d977f977833d 139 Pfam PF01894 Uncharacterised protein family UPF0047 19 135 2.3E-36 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 MKLM6_RS01140 607b4092c8dbbad7bec9d977f977833d 139 SUPERFAMILY SSF111038 1 139 1.57E-45 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 MKLM6_RS01140 607b4092c8dbbad7bec9d977f977833d 139 Gene3D G3DSA:2.60.120.460 1 139 7.4E-55 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 MKLM6_RS13255 454adf8fbf514a741c484a13f691d181 1827 Pfam PF00310 Glutamine amidotransferases class-II 24 432 3.6E-91 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain MKLM6_RS13255 454adf8fbf514a741c484a13f691d181 1827 SUPERFAMILY SSF56235 24 434 9.81E-94 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MKLM6_RS13255 454adf8fbf514a741c484a13f691d181 1827 Pfam PF01645 Conserved region in glutamate synthase 983 1295 3.0E-99 T 28-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 MKLM6_RS13255 454adf8fbf514a741c484a13f691d181 1827 SUPERFAMILY SSF51395 987 1317 1.3E-160 T 28-03-2018 MKLM6_RS13255 454adf8fbf514a741c484a13f691d181 1827 SUPERFAMILY SSF51395 459 887 1.3E-160 T 28-03-2018 MKLM6_RS13255 454adf8fbf514a741c484a13f691d181 1827 Gene3D G3DSA:3.20.20.70 445 787 1.0E-58 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS13255 454adf8fbf514a741c484a13f691d181 1827 Pfam PF04898 Glutamate synthase central domain 463 738 1.7E-73 T 28-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 MKLM6_RS13255 454adf8fbf514a741c484a13f691d181 1827 Pfam PF01493 GXGXG motif 1409 1580 5.8E-50 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 MKLM6_RS13255 454adf8fbf514a741c484a13f691d181 1827 Gene3D G3DSA:3.60.20.10 24 444 1.5E-94 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MKLM6_RS13255 454adf8fbf514a741c484a13f691d181 1827 Gene3D G3DSA:3.20.20.70 788 1344 7.0E-103 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS13255 454adf8fbf514a741c484a13f691d181 1827 SUPERFAMILY SSF69336 1410 1630 4.84E-62 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 MKLM6_RS13255 454adf8fbf514a741c484a13f691d181 1827 Gene3D G3DSA:2.160.20.60 1345 1647 7.8E-80 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 MKLM6_RS20160 389b79725e087cddafd7aca7eb4b4d69 533 Pfam PF02254 TrkA-N domain 289 405 6.0E-30 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MKLM6_RS20160 389b79725e087cddafd7aca7eb4b4d69 533 Pfam PF00520 Ion transport protein 39 268 1.8E-18 T 28-03-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 MKLM6_RS20160 389b79725e087cddafd7aca7eb4b4d69 533 PRINTS PR00169 Potassium channel signature 70 93 1.8E-15 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MKLM6_RS20160 389b79725e087cddafd7aca7eb4b4d69 533 PRINTS PR00169 Potassium channel signature 32 60 1.8E-15 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MKLM6_RS20160 389b79725e087cddafd7aca7eb4b4d69 533 PRINTS PR00169 Potassium channel signature 152 178 1.8E-15 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MKLM6_RS20160 389b79725e087cddafd7aca7eb4b4d69 533 PRINTS PR00169 Potassium channel signature 240 266 1.8E-15 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MKLM6_RS20160 389b79725e087cddafd7aca7eb4b4d69 533 PRINTS PR00169 Potassium channel signature 181 204 1.8E-15 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MKLM6_RS20160 389b79725e087cddafd7aca7eb4b4d69 533 PRINTS PR00169 Potassium channel signature 211 233 1.8E-15 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MKLM6_RS20160 389b79725e087cddafd7aca7eb4b4d69 533 Gene3D G3DSA:1.10.287.70 181 230 5.5E-11 T 28-03-2018 MKLM6_RS20160 389b79725e087cddafd7aca7eb4b4d69 533 SUPERFAMILY SSF81324 122 269 6.15E-35 T 28-03-2018 MKLM6_RS20160 389b79725e087cddafd7aca7eb4b4d69 533 SUPERFAMILY SSF81324 34 90 6.15E-35 T 28-03-2018 MKLM6_RS20160 389b79725e087cddafd7aca7eb4b4d69 533 Gene3D G3DSA:1.20.120.350 36 180 2.1E-11 T 28-03-2018 MKLM6_RS20160 389b79725e087cddafd7aca7eb4b4d69 533 Gene3D G3DSA:3.30.70.1450 424 527 6.1E-8 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MKLM6_RS20160 389b79725e087cddafd7aca7eb4b4d69 533 Gene3D G3DSA:3.40.50.720 282 404 2.3E-23 T 28-03-2018 MKLM6_RS20160 389b79725e087cddafd7aca7eb4b4d69 533 SUPERFAMILY SSF116726 428 521 1.31E-7 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MKLM6_RS20160 389b79725e087cddafd7aca7eb4b4d69 533 SUPERFAMILY SSF51735 286 425 3.25E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS20160 389b79725e087cddafd7aca7eb4b4d69 533 Gene3D G3DSA:1.20.5.110 232 268 1.8E-9 T 28-03-2018 MKLM6_RS01635 3f03111a71a0960776a588602ee84535 452 Gene3D G3DSA:1.10.630.10 2 450 2.7E-123 T 28-03-2018 MKLM6_RS01635 3f03111a71a0960776a588602ee84535 452 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 390 399 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MKLM6_RS01635 3f03111a71a0960776a588602ee84535 452 SUPERFAMILY SSF48264 5 448 2.75E-108 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MKLM6_RS01635 3f03111a71a0960776a588602ee84535 452 Pfam PF00067 Cytochrome P450 37 432 9.7E-90 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MKLM6_RS01635 3f03111a71a0960776a588602ee84535 452 PRINTS PR00385 P450 superfamily signature 264 281 5.5E-15 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MKLM6_RS01635 3f03111a71a0960776a588602ee84535 452 PRINTS PR00385 P450 superfamily signature 388 397 5.5E-15 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MKLM6_RS01635 3f03111a71a0960776a588602ee84535 452 PRINTS PR00385 P450 superfamily signature 316 327 5.5E-15 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MKLM6_RS01635 3f03111a71a0960776a588602ee84535 452 PRINTS PR00385 P450 superfamily signature 397 408 5.5E-15 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MKLM6_RS01635 3f03111a71a0960776a588602ee84535 452 PRINTS PR00463 E-class P450 group I signature 273 299 9.9E-28 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MKLM6_RS01635 3f03111a71a0960776a588602ee84535 452 PRINTS PR00463 E-class P450 group I signature 355 379 9.9E-28 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MKLM6_RS01635 3f03111a71a0960776a588602ee84535 452 PRINTS PR00463 E-class P450 group I signature 315 333 9.9E-28 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MKLM6_RS01635 3f03111a71a0960776a588602ee84535 452 PRINTS PR00463 E-class P450 group I signature 253 270 9.9E-28 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MKLM6_RS01635 3f03111a71a0960776a588602ee84535 452 PRINTS PR00463 E-class P450 group I signature 397 420 9.9E-28 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MKLM6_RS01635 3f03111a71a0960776a588602ee84535 452 PRINTS PR00463 E-class P450 group I signature 387 397 9.9E-28 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MKLM6_RS10515 9ef7249dc7a1b6288c79db08a5c96d1b 347 Pfam PF12857 TOBE-like domain 296 340 3.5E-10 T 28-03-2018 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 MKLM6_RS10515 9ef7249dc7a1b6288c79db08a5c96d1b 347 Pfam PF00005 ABC transporter 18 164 9.7E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS10515 9ef7249dc7a1b6288c79db08a5c96d1b 347 Gene3D G3DSA:2.40.50.100 265 343 4.3E-4 T 28-03-2018 MKLM6_RS10515 9ef7249dc7a1b6288c79db08a5c96d1b 347 SUPERFAMILY SSF50331 263 345 7.37E-6 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal MKLM6_RS10515 9ef7249dc7a1b6288c79db08a5c96d1b 347 Gene3D G3DSA:3.40.50.300 1 264 1.5E-76 T 28-03-2018 MKLM6_RS10515 9ef7249dc7a1b6288c79db08a5c96d1b 347 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS10515 9ef7249dc7a1b6288c79db08a5c96d1b 347 SMART SM00382 27 214 4.8E-20 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS10515 9ef7249dc7a1b6288c79db08a5c96d1b 347 SUPERFAMILY SSF52540 3 244 3.3E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS10515 9ef7249dc7a1b6288c79db08a5c96d1b 347 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 3 242 3.7E-117 T 28-03-2018 IPR005666 Sulphate transport system permease protein 1 GO:0006810|GO:0016020|GO:0042626 KEGG: 00920+3.6.3.25 MKLM6_RS02795 045266a15b4e2ac62ea0da7780f3dedb 267 Pfam PF13614 AAA domain 1 175 1.3E-43 T 28-03-2018 IPR025669 AAA domain MKLM6_RS02795 045266a15b4e2ac62ea0da7780f3dedb 267 Gene3D G3DSA:3.40.50.300 1 258 6.0E-50 T 28-03-2018 MKLM6_RS02795 045266a15b4e2ac62ea0da7780f3dedb 267 SUPERFAMILY SSF52540 1 254 1.13E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS12215 071012a5ef1024a23ea867dfe97ed4ca 137 SMART SM00448 9 121 1.1E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS12215 071012a5ef1024a23ea867dfe97ed4ca 137 Gene3D G3DSA:3.40.50.2300 3 135 5.7E-37 T 28-03-2018 MKLM6_RS12215 071012a5ef1024a23ea867dfe97ed4ca 137 Pfam PF00072 Response regulator receiver domain 11 121 2.9E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS12215 071012a5ef1024a23ea867dfe97ed4ca 137 SUPERFAMILY SSF52172 5 132 1.31E-37 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS13880 055ff7a0b9330831573f32ecd6fb73b6 156 SUPERFAMILY SSF52540 23 130 2.28E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS13880 055ff7a0b9330831573f32ecd6fb73b6 156 Gene3D G3DSA:3.40.50.300 1 147 8.4E-48 T 28-03-2018 MKLM6_RS13880 055ff7a0b9330831573f32ecd6fb73b6 156 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 8 135 5.4E-43 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 MKLM6_RS13880 055ff7a0b9330831573f32ecd6fb73b6 156 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 6 130 2.5E-39 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 MKLM6_RS20505 e801a2f2af7a299c4b29fde3ea1338e1 455 SUPERFAMILY SSF63418 1 96 1.96E-25 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MKLM6_RS20505 e801a2f2af7a299c4b29fde3ea1338e1 455 SUPERFAMILY SSF53623 99 313 2.88E-56 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MKLM6_RS20505 e801a2f2af7a299c4b29fde3ea1338e1 455 Gene3D G3DSA:3.40.1390.10 1 88 7.7E-27 T 28-03-2018 MKLM6_RS20505 e801a2f2af7a299c4b29fde3ea1338e1 455 Gene3D G3DSA:3.90.190.20 314 455 5.9E-39 T 28-03-2018 MKLM6_RS20505 e801a2f2af7a299c4b29fde3ea1338e1 455 Pfam PF01225 Mur ligase family, catalytic domain 23 93 1.8E-9 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MKLM6_RS20505 e801a2f2af7a299c4b29fde3ea1338e1 455 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 28 448 1.1E-130 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS20505 e801a2f2af7a299c4b29fde3ea1338e1 455 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 3 449 33.251 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS20505 e801a2f2af7a299c4b29fde3ea1338e1 455 Gene3D G3DSA:3.40.1190.10 89 311 1.1E-61 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MKLM6_RS20505 e801a2f2af7a299c4b29fde3ea1338e1 455 Pfam PF02875 Mur ligase family, glutamate ligase domain 317 395 2.7E-12 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MKLM6_RS20505 e801a2f2af7a299c4b29fde3ea1338e1 455 Pfam PF08245 Mur ligase middle domain 104 295 2.2E-47 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MKLM6_RS20505 e801a2f2af7a299c4b29fde3ea1338e1 455 SUPERFAMILY SSF53244 317 448 7.33E-30 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MKLM6_RS21195 89ea87c99890b02cd0fbf8ce189ac072 255 ProSitePatterns PS00727 AP endonucleases family 1 signature 2. 188 203 - T 28-03-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 MKLM6_RS21195 89ea87c99890b02cd0fbf8ce189ac072 255 Gene3D G3DSA:3.60.10.10 1 254 1.8E-54 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MKLM6_RS21195 89ea87c99890b02cd0fbf8ce189ac072 255 SUPERFAMILY SSF56219 1 253 2.75E-78 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MKLM6_RS21195 89ea87c99890b02cd0fbf8ce189ac072 255 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 252 4.6E-83 T 28-03-2018 MKLM6_RS21195 89ea87c99890b02cd0fbf8ce189ac072 255 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 253 3.6E-91 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 MKLM6_RS21195 89ea87c99890b02cd0fbf8ce189ac072 255 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 245 5.4E-25 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MKLM6_RS21195 89ea87c99890b02cd0fbf8ce189ac072 255 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 213 224 - T 28-03-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 MKLM6_RS02245 dacf1fa655a68613ecedb7dbfe77daa5 485 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 422 9.8E-151 T 28-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 MKLM6_RS02245 dacf1fa655a68613ecedb7dbfe77daa5 485 SUPERFAMILY SSF50249 39 120 3.88E-20 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS02245 dacf1fa655a68613ecedb7dbfe77daa5 485 SMART SM00316 37 115 9.5E-11 T 28-03-2018 IPR022967 RNA-binding domain, S1 MKLM6_RS02245 dacf1fa655a68613ecedb7dbfe77daa5 485 Gene3D G3DSA:2.40.50.140 32 120 1.2E-29 T 28-03-2018 MKLM6_RS02245 dacf1fa655a68613ecedb7dbfe77daa5 485 Pfam PF10150 Ribonuclease E/G family 117 389 4.2E-97 T 28-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 MKLM6_RS02245 dacf1fa655a68613ecedb7dbfe77daa5 485 Pfam PF00575 S1 RNA binding domain 38 102 9.5E-8 T 28-03-2018 IPR003029 S1 domain GO:0003676 MKLM6_RS04640 de124befba151a35e4ca0a8b60aef6f0 580 SUPERFAMILY SSF50494 305 331 3.24E-29 T 28-03-2018 IPR009003 Peptidase S1, PA clan MKLM6_RS04640 de124befba151a35e4ca0a8b60aef6f0 580 SUPERFAMILY SSF50494 398 569 3.24E-29 T 28-03-2018 IPR009003 Peptidase S1, PA clan MKLM6_RS04640 de124befba151a35e4ca0a8b60aef6f0 580 Gene3D G3DSA:2.60.200.20 2 106 2.6E-21 T 28-03-2018 MKLM6_RS04640 de124befba151a35e4ca0a8b60aef6f0 580 SUPERFAMILY SSF49879 24 105 8.03E-21 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MKLM6_RS04640 de124befba151a35e4ca0a8b60aef6f0 580 Pfam PF13365 Trypsin-like peptidase domain 312 547 1.6E-19 T 28-03-2018 MKLM6_RS04640 de124befba151a35e4ca0a8b60aef6f0 580 Pfam PF00498 FHA domain 28 95 1.1E-15 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MKLM6_RS04640 de124befba151a35e4ca0a8b60aef6f0 580 Gene3D G3DSA:2.40.10.10 447 577 1.3E-17 T 28-03-2018 MKLM6_RS04640 de124befba151a35e4ca0a8b60aef6f0 580 SMART SM00240 26 80 1.1E-10 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MKLM6_RS04640 de124befba151a35e4ca0a8b60aef6f0 580 Gene3D G3DSA:2.40.10.10 232 446 2.0E-18 T 28-03-2018 MKLM6_RS17490 569b2ddb3a02007e54c970fcf6536ebd 495 SUPERFAMILY SSF51905 47 355 5.18E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS17490 569b2ddb3a02007e54c970fcf6536ebd 495 SUPERFAMILY SSF51905 455 490 5.18E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS17490 569b2ddb3a02007e54c970fcf6536ebd 495 PRINTS PR00757 Flavin-containing amine oxidase signature 470 487 4.8E-6 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MKLM6_RS17490 569b2ddb3a02007e54c970fcf6536ebd 495 PRINTS PR00757 Flavin-containing amine oxidase signature 49 68 4.8E-6 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MKLM6_RS17490 569b2ddb3a02007e54c970fcf6536ebd 495 Gene3D G3DSA:3.50.50.60 38 495 7.0E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS17490 569b2ddb3a02007e54c970fcf6536ebd 495 Pfam PF01593 Flavin containing amine oxidoreductase 57 489 3.6E-45 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MKLM6_RS11015 4f99a321894af89c706941adef8897dc 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 5.4E-11 T 28-03-2018 MKLM6_RS11015 4f99a321894af89c706941adef8897dc 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 148 173 5.4E-11 T 28-03-2018 MKLM6_RS11015 4f99a321894af89c706941adef8897dc 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 281 5.4E-11 T 28-03-2018 MKLM6_RS11015 4f99a321894af89c706941adef8897dc 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 5.4E-11 T 28-03-2018 MKLM6_RS11015 4f99a321894af89c706941adef8897dc 407 Gene3D G3DSA:3.50.50.60 248 317 1.6E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS11015 4f99a321894af89c706941adef8897dc 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 1.9E-19 T 28-03-2018 MKLM6_RS11015 4f99a321894af89c706941adef8897dc 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 1.9E-19 T 28-03-2018 MKLM6_RS11015 4f99a321894af89c706941adef8897dc 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.9E-19 T 28-03-2018 MKLM6_RS11015 4f99a321894af89c706941adef8897dc 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 1.9E-19 T 28-03-2018 MKLM6_RS11015 4f99a321894af89c706941adef8897dc 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 1.9E-19 T 28-03-2018 MKLM6_RS11015 4f99a321894af89c706941adef8897dc 407 Gene3D G3DSA:3.50.50.60 103 243 3.8E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS11015 4f99a321894af89c706941adef8897dc 407 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 283 4.3E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS11015 4f99a321894af89c706941adef8897dc 407 SUPERFAMILY SSF51905 2 307 1.45E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS11015 4f99a321894af89c706941adef8897dc 407 Gene3D G3DSA:3.50.50.60 2 102 5.6E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS17380 b834534b1bc701c5d597cff350252a1b 523 Gene3D G3DSA:3.40.50.1980 395 512 8.2E-29 T 28-03-2018 MKLM6_RS17380 b834534b1bc701c5d597cff350252a1b 523 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 70 501 1.5E-116 T 28-03-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 MKLM6_RS17380 b834534b1bc701c5d597cff350252a1b 523 TIGRFAM TIGR01286 nifK: nitrogenase molybdenum-iron protein beta chain 2 523 1.3E-264 T 28-03-2018 IPR005976 Nitrogenase molybdenum-iron protein beta chain GO:0009399|GO:0016163|GO:0016612|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 MKLM6_RS17380 b834534b1bc701c5d597cff350252a1b 523 Gene3D G3DSA:1.20.89.10 329 394 9.9E-24 T 28-03-2018 MKLM6_RS17380 b834534b1bc701c5d597cff350252a1b 523 Gene3D G3DSA:3.40.50.1980 70 207 1.9E-45 T 28-03-2018 MKLM6_RS17380 b834534b1bc701c5d597cff350252a1b 523 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 88 95 - T 28-03-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 MKLM6_RS17380 b834534b1bc701c5d597cff350252a1b 523 Gene3D G3DSA:3.40.50.1980 219 328 2.0E-29 T 28-03-2018 MKLM6_RS17380 b834534b1bc701c5d597cff350252a1b 523 SUPERFAMILY SSF53807 3 522 1.41E-167 T 28-03-2018 MKLM6_RS17380 b834534b1bc701c5d597cff350252a1b 523 Pfam PF11844 Domain of unknown function (DUF3364) 1 56 9.1E-23 T 28-03-2018 IPR024564 Nitrogenase molybdenum-iron protein beta chain, N-terminal KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 MKLM6_RS17380 b834534b1bc701c5d597cff350252a1b 523 ProSitePatterns PS00090 Nitrogenases component 1 alpha and beta subunits signature 2. 151 165 - T 28-03-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 MKLM6_RS19925 ac45d0b10e6036570f117f7bbe8d63f0 177 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 16 131 1.5E-14 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 MKLM6_RS19925 ac45d0b10e6036570f117f7bbe8d63f0 177 SUPERFAMILY SSF56784 14 175 8.4E-42 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS19925 ac45d0b10e6036570f117f7bbe8d63f0 177 Pfam PF08282 haloacid dehalogenase-like hydrolase 86 149 8.7E-8 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS19925 ac45d0b10e6036570f117f7bbe8d63f0 177 PIRSF PIRSF006118 3 177 1.4E-66 T 28-03-2018 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MKLM6_RS19925 ac45d0b10e6036570f117f7bbe8d63f0 177 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 15 166 1.2E-52 T 28-03-2018 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MKLM6_RS19925 ac45d0b10e6036570f117f7bbe8d63f0 177 Gene3D G3DSA:3.40.50.1000 12 176 3.1E-26 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS08410 8b6225a0c7680cce35a33dcec3c899e8 236 SUPERFAMILY SSF81342 5 182 5.3E-34 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MKLM6_RS08410 8b6225a0c7680cce35a33dcec3c899e8 236 Pfam PF01292 Prokaryotic cytochrome b561 7 177 5.9E-20 T 28-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 MKLM6_RS08410 8b6225a0c7680cce35a33dcec3c899e8 236 Gene3D G3DSA:1.20.950.20 1 188 3.7E-31 T 28-03-2018 MKLM6_RS21485 5dae7c4c90a350878505404d21bbbb73 187 SUPERFAMILY SSF101874 22 186 5.49E-47 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MKLM6_RS21485 5dae7c4c90a350878505404d21bbbb73 187 Gene3D G3DSA:2.40.128.110 18 187 2.6E-42 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MKLM6_RS21485 5dae7c4c90a350878505404d21bbbb73 187 Pfam PF04264 YceI-like domain 23 184 2.0E-34 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MKLM6_RS21485 5dae7c4c90a350878505404d21bbbb73 187 SMART SM00867 22 185 1.2E-55 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MKLM6_RS20560 cc31010e0bf7f847d3dd252108c9d885 308 SUPERFAMILY SSF54211 3 125 6.98E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS20560 cc31010e0bf7f847d3dd252108c9d885 308 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 275 1.5E-109 T 28-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 MKLM6_RS20560 cc31010e0bf7f847d3dd252108c9d885 308 SUPERFAMILY SSF54211 134 276 3.64E-53 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS20560 cc31010e0bf7f847d3dd252108c9d885 308 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2 296 7.3E-120 T 28-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 MKLM6_RS20560 cc31010e0bf7f847d3dd252108c9d885 308 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 2 279 46.819 T 28-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 MKLM6_RS20560 cc31010e0bf7f847d3dd252108c9d885 308 Gene3D G3DSA:3.30.230.20 1 127 6.4E-50 T 28-03-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 MKLM6_RS20560 cc31010e0bf7f847d3dd252108c9d885 308 Gene3D G3DSA:3.30.1700.10 128 298 3.8E-68 T 28-03-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 MKLM6_RS04505 39489afb7babd3de11d7954e2e4ffdc3 89 Hamap MF_00599 Cell division protein FtsB [ftsB]. 2 89 28.242 T 28-03-2018 IPR023081 Cell division protein FtsB MKLM6_RS04505 39489afb7babd3de11d7954e2e4ffdc3 89 Pfam PF04977 Septum formation initiator 13 88 1.9E-23 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 MKLM6_RS04505 39489afb7babd3de11d7954e2e4ffdc3 89 Gene3D G3DSA:1.20.120.330 23 74 2.0E-4 T 28-03-2018 MKLM6_RS06930 d1431bb05d7115a2a0fc0224ec44f02c 477 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 4 475 3.1E-160 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MKLM6_RS06930 d1431bb05d7115a2a0fc0224ec44f02c 477 Gene3D G3DSA:2.40.33.10 83 170 5.8E-22 T 28-03-2018 MKLM6_RS06930 d1431bb05d7115a2a0fc0224ec44f02c 477 Gene3D G3DSA:3.20.20.60 1 82 3.9E-15 T 28-03-2018 MKLM6_RS06930 d1431bb05d7115a2a0fc0224ec44f02c 477 Gene3D G3DSA:3.20.20.60 171 323 6.5E-56 T 28-03-2018 MKLM6_RS06930 d1431bb05d7115a2a0fc0224ec44f02c 477 SUPERFAMILY SSF50800 72 168 2.44E-22 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain MKLM6_RS06930 d1431bb05d7115a2a0fc0224ec44f02c 477 Gene3D G3DSA:3.40.1380.20 324 476 3.4E-44 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MKLM6_RS06930 d1431bb05d7115a2a0fc0224ec44f02c 477 PRINTS PR01050 Pyruvate kinase family signature 61 77 9.6E-56 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MKLM6_RS06930 d1431bb05d7115a2a0fc0224ec44f02c 477 PRINTS PR01050 Pyruvate kinase family signature 246 270 9.6E-56 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MKLM6_RS06930 d1431bb05d7115a2a0fc0224ec44f02c 477 PRINTS PR01050 Pyruvate kinase family signature 296 314 9.6E-56 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MKLM6_RS06930 d1431bb05d7115a2a0fc0224ec44f02c 477 PRINTS PR01050 Pyruvate kinase family signature 219 245 9.6E-56 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MKLM6_RS06930 d1431bb05d7115a2a0fc0224ec44f02c 477 PRINTS PR01050 Pyruvate kinase family signature 189 203 9.6E-56 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MKLM6_RS06930 d1431bb05d7115a2a0fc0224ec44f02c 477 PRINTS PR01050 Pyruvate kinase family signature 315 331 9.6E-56 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MKLM6_RS06930 d1431bb05d7115a2a0fc0224ec44f02c 477 PRINTS PR01050 Pyruvate kinase family signature 271 295 9.6E-56 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MKLM6_RS06930 d1431bb05d7115a2a0fc0224ec44f02c 477 ProSitePatterns PS00110 Pyruvate kinase active site signature. 217 229 - T 28-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MKLM6_RS06930 d1431bb05d7115a2a0fc0224ec44f02c 477 SUPERFAMILY SSF51621 159 341 1.15E-90 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MKLM6_RS06930 d1431bb05d7115a2a0fc0224ec44f02c 477 SUPERFAMILY SSF51621 3 76 1.15E-90 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MKLM6_RS06930 d1431bb05d7115a2a0fc0224ec44f02c 477 Pfam PF02887 Pyruvate kinase, alpha/beta domain 359 473 8.9E-27 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MKLM6_RS06930 d1431bb05d7115a2a0fc0224ec44f02c 477 Pfam PF00224 Pyruvate kinase, barrel domain 4 340 6.9E-120 T 28-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MKLM6_RS06930 d1431bb05d7115a2a0fc0224ec44f02c 477 SUPERFAMILY SSF52935 325 475 1.57E-35 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MKLM6_RS08690 b87afba85bc9863e753b2fd4bd871f09 376 Gene3D G3DSA:2.60.40.420 117 251 3.3E-48 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS08690 b87afba85bc9863e753b2fd4bd871f09 376 Gene3D G3DSA:1.10.760.10 252 355 2.4E-19 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS08690 b87afba85bc9863e753b2fd4bd871f09 376 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 278 349 1.6E-11 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS08690 b87afba85bc9863e753b2fd4bd871f09 376 Gene3D G3DSA:1.10.287.90 23 115 3.4E-27 T 28-03-2018 MKLM6_RS08690 b87afba85bc9863e753b2fd4bd871f09 376 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 120 245 6.8E-37 T 28-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08690 b87afba85bc9863e753b2fd4bd871f09 376 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 192 240 - T 28-03-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08690 b87afba85bc9863e753b2fd4bd871f09 376 SUPERFAMILY SSF49503 169 308 5.81E-52 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS08690 b87afba85bc9863e753b2fd4bd871f09 376 SUPERFAMILY SSF49503 113 139 5.81E-52 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS08690 b87afba85bc9863e753b2fd4bd871f09 376 SUPERFAMILY SSF81464 20 113 2.78E-26 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08690 b87afba85bc9863e753b2fd4bd871f09 376 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 25 105 1.9E-15 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08690 b87afba85bc9863e753b2fd4bd871f09 376 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 35 256 6.0E-58 T 28-03-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08690 b87afba85bc9863e753b2fd4bd871f09 376 PRINTS PR01166 Cytochrome c oxidase subunit II signature 116 135 1.9E-38 T 28-03-2018 MKLM6_RS08690 b87afba85bc9863e753b2fd4bd871f09 376 PRINTS PR01166 Cytochrome c oxidase subunit II signature 82 94 1.9E-38 T 28-03-2018 MKLM6_RS08690 b87afba85bc9863e753b2fd4bd871f09 376 PRINTS PR01166 Cytochrome c oxidase subunit II signature 211 228 1.9E-38 T 28-03-2018 MKLM6_RS08690 b87afba85bc9863e753b2fd4bd871f09 376 PRINTS PR01166 Cytochrome c oxidase subunit II signature 191 211 1.9E-38 T 28-03-2018 MKLM6_RS08690 b87afba85bc9863e753b2fd4bd871f09 376 PRINTS PR01166 Cytochrome c oxidase subunit II signature 94 114 1.9E-38 T 28-03-2018 MKLM6_RS08690 b87afba85bc9863e753b2fd4bd871f09 376 PRINTS PR01166 Cytochrome c oxidase subunit II signature 167 188 1.9E-38 T 28-03-2018 MKLM6_RS08690 b87afba85bc9863e753b2fd4bd871f09 376 PRINTS PR01166 Cytochrome c oxidase subunit II signature 229 246 1.9E-38 T 28-03-2018 MKLM6_RS12390 cb59ce1574f05895a2cf0820d744f424 454 Pfam PF02055 Glycosyl hydrolase family 30 TIM-barrel domain 57 353 5.4E-40 T 28-03-2018 IPR033453 Glycosyl hydrolase family 30, TIM-barrel domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 MKLM6_RS12390 cb59ce1574f05895a2cf0820d744f424 454 Gene3D G3DSA:2.60.40.1180 385 454 1.3E-13 T 28-03-2018 MKLM6_RS12390 cb59ce1574f05895a2cf0820d744f424 454 SUPERFAMILY SSF51445 56 392 1.01E-73 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily MKLM6_RS12390 cb59ce1574f05895a2cf0820d744f424 454 Pfam PF17189 Glycosyl hydrolase family 30 beta sandwich domain 391 449 1.3E-11 T 28-03-2018 IPR033452 Glycosyl hydrolase family 30, beta sandwich domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 MKLM6_RS12390 cb59ce1574f05895a2cf0820d744f424 454 Gene3D G3DSA:3.20.20.80 54 384 1.1E-80 T 28-03-2018 MKLM6_RS18415 0e728ded4b38720c11d2d643335d82da 110 SUPERFAMILY SSF54843 2 110 8.63E-41 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18415 0e728ded4b38720c11d2d643335d82da 110 Gene3D G3DSA:3.90.470.10 1 110 3.2E-42 T 28-03-2018 MKLM6_RS18415 0e728ded4b38720c11d2d643335d82da 110 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 25.797 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18415 0e728ded4b38720c11d2d643335d82da 110 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 1.1E-40 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18415 0e728ded4b38720c11d2d643335d82da 110 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 3.9E-35 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18415 0e728ded4b38720c11d2d643335d82da 110 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 28-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS14110 fab025e44dc5bd4c07167167e8294306 729 Pfam PF00563 EAL domain 472 705 1.2E-70 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14110 fab025e44dc5bd4c07167167e8294306 729 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 291 454 1.6E-34 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS14110 fab025e44dc5bd4c07167167e8294306 729 Pfam PF13426 PAS domain 180 282 4.2E-17 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14110 fab025e44dc5bd4c07167167e8294306 729 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 166 289 2.0E-22 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14110 fab025e44dc5bd4c07167167e8294306 729 Pfam PF13185 GAF domain 21 160 7.8E-12 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS14110 fab025e44dc5bd4c07167167e8294306 729 SUPERFAMILY SSF55073 299 456 1.88E-43 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS14110 fab025e44dc5bd4c07167167e8294306 729 Gene3D G3DSA:3.20.20.450 459 724 9.2E-101 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14110 fab025e44dc5bd4c07167167e8294306 729 SMART SM00086 241 283 1.9E-8 T 28-03-2018 IPR001610 PAC motif MKLM6_RS14110 fab025e44dc5bd4c07167167e8294306 729 SMART SM00065 13 169 2.4E-5 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS14110 fab025e44dc5bd4c07167167e8294306 729 SUPERFAMILY SSF141868 471 718 4.97E-89 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14110 fab025e44dc5bd4c07167167e8294306 729 Gene3D G3DSA:3.30.70.270 292 458 2.4E-52 T 28-03-2018 MKLM6_RS14110 fab025e44dc5bd4c07167167e8294306 729 SUPERFAMILY SSF55781 21 169 3.49E-23 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS14110 fab025e44dc5bd4c07167167e8294306 729 SMART SM00052 465 710 2.7E-117 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14110 fab025e44dc5bd4c07167167e8294306 729 Pfam PF00990 Diguanylate cyclase, GGDEF domain 295 450 9.5E-43 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS14110 fab025e44dc5bd4c07167167e8294306 729 PIRSF PIRSF005925 2 170 3.1E-29 T 28-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase MKLM6_RS14110 fab025e44dc5bd4c07167167e8294306 729 PIRSF PIRSF005925 158 288 3.3E-14 T 28-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase MKLM6_RS14110 fab025e44dc5bd4c07167167e8294306 729 PIRSF PIRSF005925 282 725 1.0E-130 T 28-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase MKLM6_RS14110 fab025e44dc5bd4c07167167e8294306 729 SMART SM00267 283 455 1.1E-54 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS14110 fab025e44dc5bd4c07167167e8294306 729 SMART SM00091 169 235 2.4E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14110 fab025e44dc5bd4c07167167e8294306 729 Gene3D G3DSA:3.30.450.40 1 170 7.6E-18 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS14110 fab025e44dc5bd4c07167167e8294306 729 SUPERFAMILY SSF55785 178 280 3.32E-28 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14110 fab025e44dc5bd4c07167167e8294306 729 Gene3D G3DSA:3.30.450.20 171 291 1.7E-28 T 28-03-2018 MKLM6_RS22725 cd76a63034503c3a23ee929ce7677258 142 SUPERFAMILY SSF143081 2 142 9.03E-51 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) MKLM6_RS22725 cd76a63034503c3a23ee929ce7677258 142 Gene3D G3DSA:3.90.1680.10 1 142 4.9E-52 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) MKLM6_RS22725 cd76a63034503c3a23ee929ce7677258 142 Pfam PF02586 SOS response associated peptidase (SRAP) 2 130 3.3E-44 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) MKLM6_RS19670 02313f1523321362feadaa4a4119212c 142 Pfam PF10116 Protein required for attachment to host cells 6 141 8.1E-41 T 28-03-2018 IPR019291 Host attachment protein MKLM6_RS19670 02313f1523321362feadaa4a4119212c 142 Gene3D G3DSA:3.30.420.60 3 141 1.3E-12 T 28-03-2018 MKLM6_RS14675 4aab21fe5e7c27009983cb5825e69b6a 209 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 6 204 4.3E-81 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MKLM6_RS14675 4aab21fe5e7c27009983cb5825e69b6a 209 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 125 138 - T 28-03-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MKLM6_RS14675 4aab21fe5e7c27009983cb5825e69b6a 209 SUPERFAMILY SSF51569 3 206 2.38E-70 T 28-03-2018 MKLM6_RS14675 4aab21fe5e7c27009983cb5825e69b6a 209 Pfam PF01081 KDPG and KHG aldolase 5 199 2.2E-78 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MKLM6_RS14675 4aab21fe5e7c27009983cb5825e69b6a 209 Gene3D G3DSA:3.20.20.70 3 208 2.2E-34 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS14675 4aab21fe5e7c27009983cb5825e69b6a 209 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 37 46 - T 28-03-2018 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MKLM6_RS00850 ec76d17583a7e60b975d663297ed98c1 520 SUPERFAMILY SSF52242 23 129 1.29E-8 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MKLM6_RS00850 ec76d17583a7e60b975d663297ed98c1 520 Pfam PF04055 Radical SAM superfamily 190 349 9.0E-14 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS00850 ec76d17583a7e60b975d663297ed98c1 520 Gene3D G3DSA:3.40.50.280 6 133 1.1E-17 T 28-03-2018 MKLM6_RS00850 ec76d17583a7e60b975d663297ed98c1 520 Pfam PF02310 B12 binding domain 15 130 2.9E-20 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MKLM6_RS00850 ec76d17583a7e60b975d663297ed98c1 520 SMART SM00729 186 390 4.4E-17 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MKLM6_RS00850 ec76d17583a7e60b975d663297ed98c1 520 Gene3D G3DSA:3.20.20.70 156 456 9.5E-25 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS00850 ec76d17583a7e60b975d663297ed98c1 520 SUPERFAMILY SSF102114 173 374 3.92E-27 T 28-03-2018 MKLM6_RS00850 ec76d17583a7e60b975d663297ed98c1 520 TIGRFAM TIGR04367 HpnR_B12_rSAM: hopanoid C-3 methylase HpnR 1 492 7.2E-258 T 28-03-2018 IPR027564 Hopanoid C-3 methylase HpnR MKLM6_RS07965 46b51276bd43b3191b664cf4e55a35a3 750 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 329 598 3.1E-39 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MKLM6_RS07965 46b51276bd43b3191b664cf4e55a35a3 750 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 613 696 1.8E-13 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MKLM6_RS07965 46b51276bd43b3191b664cf4e55a35a3 750 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 49 181 6.5E-16 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MKLM6_RS07965 46b51276bd43b3191b664cf4e55a35a3 750 Gene3D G3DSA:3.90.1170.50 194 339 6.5E-29 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MKLM6_RS07965 46b51276bd43b3191b664cf4e55a35a3 750 SMART SM01008 215 302 3.4E-21 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MKLM6_RS07965 46b51276bd43b3191b664cf4e55a35a3 750 Gene3D G3DSA:3.30.365.10 340 434 5.1E-34 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MKLM6_RS07965 46b51276bd43b3191b664cf4e55a35a3 750 SUPERFAMILY SSF56003 19 247 4.88E-42 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MKLM6_RS07965 46b51276bd43b3191b664cf4e55a35a3 750 Gene3D G3DSA:3.30.365.10 435 605 2.4E-33 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MKLM6_RS07965 46b51276bd43b3191b664cf4e55a35a3 750 Gene3D G3DSA:3.30.365.10 606 748 3.2E-33 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MKLM6_RS07965 46b51276bd43b3191b664cf4e55a35a3 750 Gene3D G3DSA:3.30.365.10 33 193 4.2E-40 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MKLM6_RS07965 46b51276bd43b3191b664cf4e55a35a3 750 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 11 28 5.8E-4 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal MKLM6_RS07965 46b51276bd43b3191b664cf4e55a35a3 750 SUPERFAMILY SSF56003 325 745 7.33E-109 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MKLM6_RS07965 46b51276bd43b3191b664cf4e55a35a3 750 PIRSF PIRSF036389 1 750 1.6E-232 T 28-03-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related MKLM6_RS04750 7c4c512871b0e87372bbe470ecd40415 602 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 233 598 1.5E-160 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MKLM6_RS04750 7c4c512871b0e87372bbe470ecd40415 602 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 2 598 36.511 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MKLM6_RS04750 7c4c512871b0e87372bbe470ecd40415 602 Pfam PF03814 Potassium-transporting ATPase A subunit 11 596 1.2E-248 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MKLM6_RS04750 7c4c512871b0e87372bbe470ecd40415 602 PIRSF PIRSF001294 1 600 3.9E-245 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MKLM6_RS22225 b3f6c1608e66151f4546e9034e5ebcf6 639 SUPERFAMILY SSF52540 476 606 1.91E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS22225 b3f6c1608e66151f4546e9034e5ebcf6 639 SUPERFAMILY SSF52540 280 332 1.91E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS22225 b3f6c1608e66151f4546e9034e5ebcf6 639 SMART SM00490 477 560 1.7E-14 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS22225 b3f6c1608e66151f4546e9034e5ebcf6 639 Gene3D G3DSA:3.40.50.300 240 428 2.2E-18 T 28-03-2018 MKLM6_RS22225 b3f6c1608e66151f4546e9034e5ebcf6 639 SUPERFAMILY SSF52540 227 421 1.36E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS22225 b3f6c1608e66151f4546e9034e5ebcf6 639 SMART SM00487 255 430 2.2E-10 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MKLM6_RS22225 b3f6c1608e66151f4546e9034e5ebcf6 639 Gene3D G3DSA:3.40.50.300 429 601 2.8E-21 T 28-03-2018 MKLM6_RS22225 b3f6c1608e66151f4546e9034e5ebcf6 639 SUPERFAMILY SSF50249 5 156 2.4E-7 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS22225 b3f6c1608e66151f4546e9034e5ebcf6 639 Pfam PF04851 Type III restriction enzyme, res subunit 258 334 4.4E-5 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MKLM6_RS22225 b3f6c1608e66151f4546e9034e5ebcf6 639 Pfam PF00271 Helicase conserved C-terminal domain 481 560 2.7E-13 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS18545 ab45d918d20a34cb634d282498500def 317 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 7 123 2.1E-48 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MKLM6_RS18545 ab45d918d20a34cb634d282498500def 317 Gene3D G3DSA:3.40.50.2020 158 292 3.3E-38 T 28-03-2018 MKLM6_RS18545 ab45d918d20a34cb634d282498500def 317 Gene3D G3DSA:3.40.50.2020 3 157 1.3E-62 T 28-03-2018 MKLM6_RS18545 ab45d918d20a34cb634d282498500def 317 Pfam PF14572 Phosphoribosyl synthetase-associated domain 206 315 1.6E-27 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MKLM6_RS18545 ab45d918d20a34cb634d282498500def 317 SUPERFAMILY SSF53271 71 305 5.23E-63 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like MKLM6_RS18545 ab45d918d20a34cb634d282498500def 317 SMART SM01400 6 123 3.1E-76 T 28-03-2018 MKLM6_RS18545 ab45d918d20a34cb634d282498500def 317 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 131 146 - T 28-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 MKLM6_RS18545 ab45d918d20a34cb634d282498500def 317 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 7 315 9.5E-119 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MKLM6_RS18545 ab45d918d20a34cb634d282498500def 317 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 6 316 48.987 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MKLM6_RS15940 675c9c86a0c9e35e4d75683db331d5c7 239 SMART SM00421 161 218 2.2E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS15940 675c9c86a0c9e35e4d75683db331d5c7 239 Gene3D G3DSA:1.10.10.10 148 220 9.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS15940 675c9c86a0c9e35e4d75683db331d5c7 239 SUPERFAMILY SSF52172 29 167 4.55E-11 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS15940 675c9c86a0c9e35e4d75683db331d5c7 239 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 194 206 1.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS15940 675c9c86a0c9e35e4d75683db331d5c7 239 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 178 1.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS15940 675c9c86a0c9e35e4d75683db331d5c7 239 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 194 1.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS15940 675c9c86a0c9e35e4d75683db331d5c7 239 Pfam PF00196 Bacterial regulatory proteins, luxR family 163 215 4.4E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS15940 675c9c86a0c9e35e4d75683db331d5c7 239 ProSitePatterns PS00622 LuxR-type HTH domain signature. 178 205 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS15940 675c9c86a0c9e35e4d75683db331d5c7 239 Gene3D G3DSA:3.40.50.2300 27 147 2.0E-7 T 28-03-2018 MKLM6_RS15940 675c9c86a0c9e35e4d75683db331d5c7 239 SUPERFAMILY SSF46894 148 217 8.5E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MKLM6_RS18655 d774e2bb32fe06c78155d53dbcc92593 693 SUPERFAMILY SSF141868 448 692 5.36E-90 T 28-03-2018 IPR001633 EAL domain MKLM6_RS18655 d774e2bb32fe06c78155d53dbcc92593 693 SMART SM00086 219 261 8.0E-11 T 28-03-2018 IPR001610 PAC motif MKLM6_RS18655 d774e2bb32fe06c78155d53dbcc92593 693 Pfam PF00990 Diguanylate cyclase, GGDEF domain 272 429 5.1E-52 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS18655 d774e2bb32fe06c78155d53dbcc92593 693 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 144 266 6.6E-23 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18655 d774e2bb32fe06c78155d53dbcc92593 693 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 269 431 1.0E-42 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS18655 d774e2bb32fe06c78155d53dbcc92593 693 SMART SM00052 443 687 1.8E-122 T 28-03-2018 IPR001633 EAL domain MKLM6_RS18655 d774e2bb32fe06c78155d53dbcc92593 693 Gene3D G3DSA:3.20.20.450 442 693 1.5E-100 T 28-03-2018 IPR001633 EAL domain MKLM6_RS18655 d774e2bb32fe06c78155d53dbcc92593 693 Gene3D G3DSA:3.30.450.20 120 286 5.4E-31 T 28-03-2018 MKLM6_RS18655 d774e2bb32fe06c78155d53dbcc92593 693 SMART SM00267 260 433 1.2E-70 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS18655 d774e2bb32fe06c78155d53dbcc92593 693 SUPERFAMILY SSF55785 156 258 1.92E-29 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18655 d774e2bb32fe06c78155d53dbcc92593 693 SMART SM00091 147 213 5.8E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18655 d774e2bb32fe06c78155d53dbcc92593 693 SUPERFAMILY SSF55073 277 434 3.92E-52 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS18655 d774e2bb32fe06c78155d53dbcc92593 693 Gene3D G3DSA:3.30.70.270 287 441 3.8E-62 T 28-03-2018 MKLM6_RS18655 d774e2bb32fe06c78155d53dbcc92593 693 Pfam PF00563 EAL domain 449 682 9.4E-70 T 28-03-2018 IPR001633 EAL domain MKLM6_RS18655 d774e2bb32fe06c78155d53dbcc92593 693 Pfam PF13426 PAS domain 158 260 5.8E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS00590 e95b4521cd09d795db4d68b1a26cc841 622 Pfam PF13932 GidA associated domain 402 614 1.4E-79 T 28-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 MKLM6_RS00590 e95b4521cd09d795db4d68b1a26cc841 622 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 MKLM6_RS00590 e95b4521cd09d795db4d68b1a26cc841 622 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 MKLM6_RS00590 e95b4521cd09d795db4d68b1a26cc841 622 Pfam PF01134 Glucose inhibited division protein A 8 398 8.0E-167 T 28-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 MKLM6_RS00590 e95b4521cd09d795db4d68b1a26cc841 622 SUPERFAMILY SSF51905 97 261 1.69E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS00590 e95b4521cd09d795db4d68b1a26cc841 622 SUPERFAMILY SSF51905 5 66 1.69E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS00590 e95b4521cd09d795db4d68b1a26cc841 622 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 622 42.863 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 MKLM6_RS00590 e95b4521cd09d795db4d68b1a26cc841 622 Gene3D G3DSA:3.50.50.60 5 264 2.1E-77 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS00590 e95b4521cd09d795db4d68b1a26cc841 622 SMART SM01228 544 615 1.6E-43 T 28-03-2018 MKLM6_RS00590 e95b4521cd09d795db4d68b1a26cc841 622 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 620 5.6E-280 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 MKLM6_RS04710 45c1ca967c261cfaa7c6a2392d597240 228 Pfam PF13280 WYL domain 137 222 3.3E-19 T 28-03-2018 IPR026881 WYL domain MKLM6_RS04710 45c1ca967c261cfaa7c6a2392d597240 228 Gene3D G3DSA:1.10.10.10 1 65 2.6E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS04710 45c1ca967c261cfaa7c6a2392d597240 228 Pfam PF08279 HTH domain 6 58 4.1E-18 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 MKLM6_RS04710 45c1ca967c261cfaa7c6a2392d597240 228 SUPERFAMILY SSF46785 1 61 4.88E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS04710 45c1ca967c261cfaa7c6a2392d597240 228 SMART SM00420 6 58 0.006 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MKLM6_RS09335 88e9638485b885e804587a9a2d920823 225 SUPERFAMILY SSF51161 29 203 7.49E-35 T 28-03-2018 IPR011004 Trimeric LpxA-like MKLM6_RS09335 88e9638485b885e804587a9a2d920823 225 Gene3D G3DSA:2.160.10.10 98 168 7.7E-18 T 28-03-2018 MKLM6_RS09335 88e9638485b885e804587a9a2d920823 225 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 153 181 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MKLM6_RS09335 88e9638485b885e804587a9a2d920823 225 Gene3D G3DSA:2.160.10.10 169 205 1.9E-8 T 28-03-2018 MKLM6_RS09335 88e9638485b885e804587a9a2d920823 225 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 164 195 1.4E-4 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS09335 88e9638485b885e804587a9a2d920823 225 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 127 161 7.2E-8 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS09335 88e9638485b885e804587a9a2d920823 225 Gene3D G3DSA:3.40.50.20 3 96 1.7E-6 T 28-03-2018 MKLM6_RS02225 8f40c641151b93468c25255518372e2a 164 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 6 154 4.8E-62 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 MKLM6_RS02225 8f40c641151b93468c25255518372e2a 164 Pfam PF01967 MoaC family 17 152 9.6E-55 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 MKLM6_RS02225 8f40c641151b93468c25255518372e2a 164 Gene3D G3DSA:3.30.70.640 4 160 3.0E-68 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 MKLM6_RS02225 8f40c641151b93468c25255518372e2a 164 SUPERFAMILY SSF55040 13 157 1.7E-60 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 MKLM6_RS02225 8f40c641151b93468c25255518372e2a 164 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 4 160 35.928 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 MKLM6_RS01145 53004144a46df34f66f2a2caecb73e99 154 Pfam PF04214 Protein of unknown function, DUF 57 124 2.5E-33 T 28-03-2018 IPR007332 Protein of unknown function DUF411 MKLM6_RS01145 53004144a46df34f66f2a2caecb73e99 154 SUPERFAMILY SSF52833 26 104 2.4E-5 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS05830 0b690f2654ebb442fc9095ea99d56fd0 214 SUPERFAMILY SSF53474 4 201 6.89E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS05830 0b690f2654ebb442fc9095ea99d56fd0 214 Gene3D G3DSA:3.40.50.1820 1 209 1.1E-11 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS05830 0b690f2654ebb442fc9095ea99d56fd0 214 Pfam PF05728 Uncharacterised protein family (UPF0227) 5 196 9.5E-22 T 28-03-2018 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA MKLM6_RS02285 3c6118ca7668e0ae981be0c103a3b9ff 86 Pfam PF09630 Domain of unknown function (DUF2024) 1 81 6.9E-36 T 28-03-2018 IPR018592 Protein of unknown function DUF2024 MKLM6_RS02285 3c6118ca7668e0ae981be0c103a3b9ff 86 Gene3D G3DSA:3.10.510.10 1 84 1.8E-37 T 28-03-2018 IPR023122 NE1680-like domain MKLM6_RS02285 3c6118ca7668e0ae981be0c103a3b9ff 86 SUPERFAMILY SSF160766 1 85 5.49E-37 T 28-03-2018 IPR023122 NE1680-like domain MKLM6_RS10925 316daa92120cd1f49a0d65c42c03c8e7 368 TIGRFAM TIGR02913 HAF_rpt: probable extracellular repeat, HAF family 42 82 7.1E-13 T 28-03-2018 IPR014262 Extracellular HAF MKLM6_RS10925 316daa92120cd1f49a0d65c42c03c8e7 368 TIGRFAM TIGR02913 HAF_rpt: probable extracellular repeat, HAF family 131 170 6.3E-16 T 28-03-2018 IPR014262 Extracellular HAF MKLM6_RS10925 316daa92120cd1f49a0d65c42c03c8e7 368 TIGRFAM TIGR02913 HAF_rpt: probable extracellular repeat, HAF family 87 126 2.5E-13 T 28-03-2018 IPR014262 Extracellular HAF MKLM6_RS10925 316daa92120cd1f49a0d65c42c03c8e7 368 TIGRFAM TIGR02913 HAF_rpt: probable extracellular repeat, HAF family 175 214 6.2E-17 T 28-03-2018 IPR014262 Extracellular HAF MKLM6_RS10925 316daa92120cd1f49a0d65c42c03c8e7 368 TIGRFAM TIGR02913 HAF_rpt: probable extracellular repeat, HAF family 265 300 8.1E-15 T 28-03-2018 IPR014262 Extracellular HAF MKLM6_RS10925 316daa92120cd1f49a0d65c42c03c8e7 368 TIGRFAM TIGR02913 HAF_rpt: probable extracellular repeat, HAF family 220 258 2.6E-10 T 28-03-2018 IPR014262 Extracellular HAF MKLM6_RS10925 316daa92120cd1f49a0d65c42c03c8e7 368 TIGRFAM TIGR03370 VPLPA-CTERM: VPLPA-CTERM protein sorting domain 343 366 2.3E-6 T 28-03-2018 IPR022472 VPLPA-CTERM protein sorting domain MKLM6_RS10925 316daa92120cd1f49a0d65c42c03c8e7 368 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 343 366 0.0016 T 28-03-2018 IPR013424 PEP-CTERM protein-sorting domain MKLM6_RS10925 316daa92120cd1f49a0d65c42c03c8e7 368 Pfam PF11949 Protein of unknown function (DUF3466) 172 332 1.5E-7 T 28-03-2018 IPR022562 Protein of unknown function DUF3466 MKLM6_RS01010 ae3b756fc1d0c6bb90c4a7700b57fadf 352 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 28-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 MKLM6_RS01010 ae3b756fc1d0c6bb90c4a7700b57fadf 352 PIRSF PIRSF002401 1 351 1.8E-133 T 28-03-2018 IPR035101 GTP-binding protein, Obg-type MKLM6_RS01010 ae3b756fc1d0c6bb90c4a7700b57fadf 352 Gene3D G3DSA:2.70.210.12 2 156 1.6E-56 T 28-03-2018 IPR006169 GTP1/OBG domain MKLM6_RS01010 ae3b756fc1d0c6bb90c4a7700b57fadf 352 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 3.5E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS01010 ae3b756fc1d0c6bb90c4a7700b57fadf 352 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 3.5E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS01010 ae3b756fc1d0c6bb90c4a7700b57fadf 352 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 3.5E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS01010 ae3b756fc1d0c6bb90c4a7700b57fadf 352 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 3.5E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS01010 ae3b756fc1d0c6bb90c4a7700b57fadf 352 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 333 1.0E-140 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 MKLM6_RS01010 ae3b756fc1d0c6bb90c4a7700b57fadf 352 Pfam PF01926 50S ribosome-binding GTPase 161 285 2.1E-25 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS01010 ae3b756fc1d0c6bb90c4a7700b57fadf 352 Hamap MF_01454 GTPase Obg [obg]. 2 334 46.519 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 MKLM6_RS01010 ae3b756fc1d0c6bb90c4a7700b57fadf 352 SUPERFAMILY SSF82051 3 157 1.96E-55 T 28-03-2018 IPR006169 GTP1/OBG domain MKLM6_RS01010 ae3b756fc1d0c6bb90c4a7700b57fadf 352 Pfam PF01018 GTP1/OBG 4 157 1.5E-57 T 28-03-2018 IPR006169 GTP1/OBG domain MKLM6_RS01010 ae3b756fc1d0c6bb90c4a7700b57fadf 352 Gene3D G3DSA:3.40.50.300 159 345 1.6E-35 T 28-03-2018 MKLM6_RS01010 ae3b756fc1d0c6bb90c4a7700b57fadf 352 SUPERFAMILY SSF52540 152 343 1.64E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS09475 42a7bdc6b2862bc55813d5c9605a4d01 635 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 633 34.399 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MKLM6_RS09475 42a7bdc6b2862bc55813d5c9605a4d01 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 361 384 1.6E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MKLM6_RS09475 42a7bdc6b2862bc55813d5c9605a4d01 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 328 356 1.6E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MKLM6_RS09475 42a7bdc6b2862bc55813d5c9605a4d01 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 463 491 1.6E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MKLM6_RS09475 42a7bdc6b2862bc55813d5c9605a4d01 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 533 545 1.6E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MKLM6_RS09475 42a7bdc6b2862bc55813d5c9605a4d01 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 506 519 1.6E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MKLM6_RS09475 42a7bdc6b2862bc55813d5c9605a4d01 635 SUPERFAMILY SSF55681 242 525 6.77E-98 T 28-03-2018 MKLM6_RS09475 42a7bdc6b2862bc55813d5c9605a4d01 635 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 630 8.4E-226 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MKLM6_RS09475 42a7bdc6b2862bc55813d5c9605a4d01 635 Gene3D G3DSA:3.40.50.800 531 635 1.5E-25 T 28-03-2018 IPR004154 Anticodon-binding MKLM6_RS09475 42a7bdc6b2862bc55813d5c9605a4d01 635 SUPERFAMILY SSF52954 528 633 2.27E-29 T 28-03-2018 IPR004154 Anticodon-binding MKLM6_RS09475 42a7bdc6b2862bc55813d5c9605a4d01 635 Pfam PF03129 Anticodon binding domain 540 629 1.9E-20 T 28-03-2018 IPR004154 Anticodon-binding MKLM6_RS09475 42a7bdc6b2862bc55813d5c9605a4d01 635 SUPERFAMILY SSF55186 64 240 1.83E-67 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 MKLM6_RS09475 42a7bdc6b2862bc55813d5c9605a4d01 635 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 317 528 1.5E-43 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS09475 42a7bdc6b2862bc55813d5c9605a4d01 635 SUPERFAMILY SSF81271 3 61 1.0E-16 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MKLM6_RS09475 42a7bdc6b2862bc55813d5c9605a4d01 635 SMART SM00863 169 218 2.3E-26 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 MKLM6_RS09475 42a7bdc6b2862bc55813d5c9605a4d01 635 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 170 218 9.3E-17 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 MKLM6_RS09475 42a7bdc6b2862bc55813d5c9605a4d01 635 Gene3D G3DSA:3.30.54.20 141 186 3.1E-20 T 28-03-2018 MKLM6_RS09475 42a7bdc6b2862bc55813d5c9605a4d01 635 Gene3D G3DSA:3.30.930.10 220 530 2.7E-120 T 28-03-2018 MKLM6_RS09475 42a7bdc6b2862bc55813d5c9605a4d01 635 Gene3D G3DSA:3.10.20.30 1 64 6.8E-20 T 28-03-2018 IPR012675 Beta-grasp domain MKLM6_RS09475 42a7bdc6b2862bc55813d5c9605a4d01 635 Pfam PF02824 TGS domain 4 61 8.6E-14 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 MKLM6_RS09475 42a7bdc6b2862bc55813d5c9605a4d01 635 Gene3D G3DSA:3.30.980.10 65 140 1.4E-23 T 28-03-2018 MKLM6_RS08800 479517c8bb1402e789a4b4ed512ddb93 118 TIGRFAM TIGR03010 sulf_tusC_dsrF: sulfur relay protein TusC/DsrF 4 110 2.2E-34 T 28-03-2018 IPR017462 Sulphur relay, TusC/DsrF MKLM6_RS08800 479517c8bb1402e789a4b4ed512ddb93 118 SUPERFAMILY SSF75169 1 111 1.41E-28 T 28-03-2018 IPR027396 DsrEFH-like MKLM6_RS08800 479517c8bb1402e789a4b4ed512ddb93 118 Pfam PF02635 DsrE/DsrF-like family 2 109 9.6E-16 T 28-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein MKLM6_RS08800 479517c8bb1402e789a4b4ed512ddb93 118 Gene3D G3DSA:3.40.1260.10 1 114 1.5E-17 T 28-03-2018 MKLM6_RS02575 706401c8de726dea267df0360a77f7b7 260 Gene3D G3DSA:3.40.50.10090 124 251 9.5E-19 T 28-03-2018 MKLM6_RS02575 706401c8de726dea267df0360a77f7b7 260 SUPERFAMILY SSF69618 8 249 4.19E-51 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MKLM6_RS02575 706401c8de726dea267df0360a77f7b7 260 Gene3D G3DSA:3.40.50.10090 7 121 1.1E-25 T 28-03-2018 MKLM6_RS02575 706401c8de726dea267df0360a77f7b7 260 Pfam PF02602 Uroporphyrinogen-III synthase HemD 23 244 1.3E-44 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MKLM6_RS22460 bfc074130ca2fefd16989f14b2e40b3a 322 SUPERFAMILY SSF53067 1 157 4.47E-27 T 28-03-2018 MKLM6_RS22460 bfc074130ca2fefd16989f14b2e40b3a 322 Gene3D G3DSA:3.30.420.40 170 297 7.3E-6 T 28-03-2018 MKLM6_RS22460 bfc074130ca2fefd16989f14b2e40b3a 322 SUPERFAMILY SSF53067 167 320 1.24E-18 T 28-03-2018 MKLM6_RS22460 bfc074130ca2fefd16989f14b2e40b3a 322 Gene3D G3DSA:3.30.420.40 2 169 3.1E-24 T 28-03-2018 MKLM6_RS21660 64b28c564a77d9e88f612879d60ee858 130 Pfam PF00581 Rhodanese-like domain 7 103 1.9E-11 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS21660 64b28c564a77d9e88f612879d60ee858 130 SMART SM00450 6 113 2.0E-13 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS21660 64b28c564a77d9e88f612879d60ee858 130 SUPERFAMILY SSF52821 3 128 1.31E-23 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS21660 64b28c564a77d9e88f612879d60ee858 130 Gene3D G3DSA:3.40.250.10 1 130 6.0E-24 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS01465 7ff0aa2b49696063b926c0b1251e604f 161 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 158 2.3E-62 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MKLM6_RS01465 7ff0aa2b49696063b926c0b1251e604f 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 3 21 7.6E-49 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MKLM6_RS01465 7ff0aa2b49696063b926c0b1251e604f 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 7.6E-49 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MKLM6_RS01465 7ff0aa2b49696063b926c0b1251e604f 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 7.6E-49 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MKLM6_RS01465 7ff0aa2b49696063b926c0b1251e604f 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 7.6E-49 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MKLM6_RS01465 7ff0aa2b49696063b926c0b1251e604f 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 21 42 7.6E-49 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MKLM6_RS01465 7ff0aa2b49696063b926c0b1251e604f 161 SUPERFAMILY SSF52374 4 157 6.44E-46 T 28-03-2018 MKLM6_RS01465 7ff0aa2b49696063b926c0b1251e604f 161 Pfam PF01467 Cytidylyltransferase-like 6 134 2.6E-20 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MKLM6_RS01465 7ff0aa2b49696063b926c0b1251e604f 161 Gene3D G3DSA:3.40.50.620 1 159 4.6E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS01465 7ff0aa2b49696063b926c0b1251e604f 161 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 12 78 9.0E-4 T 28-03-2018 MKLM6_RS01465 7ff0aa2b49696063b926c0b1251e604f 161 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 60 1.3E-16 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MKLM6_RS01465 7ff0aa2b49696063b926c0b1251e604f 161 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 3 159 36.512 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MKLM6_RS11140 bdff2efd831ca22329b0a9167263bc75 326 Gene3D G3DSA:1.10.10.10 161 211 2.2E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS11140 bdff2efd831ca22329b0a9167263bc75 326 Gene3D G3DSA:1.10.601.10 2 160 1.0E-58 T 28-03-2018 MKLM6_RS11140 bdff2efd831ca22329b0a9167263bc75 326 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 87 314 1.3E-33 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11140 bdff2efd831ca22329b0a9167263bc75 326 Hamap MF_00959 RNA polymerase sigma factor RpoS [rpoS]. 3 325 37.617 T 28-03-2018 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11140 bdff2efd831ca22329b0a9167263bc75 326 SUPERFAMILY SSF88659 164 236 3.01E-12 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11140 bdff2efd831ca22329b0a9167263bc75 326 Pfam PF00140 Sigma-70 factor, region 1.2 53 85 2.8E-9 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11140 bdff2efd831ca22329b0a9167263bc75 326 Pfam PF04542 Sigma-70 region 2 91 160 3.0E-20 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11140 bdff2efd831ca22329b0a9167263bc75 326 PRINTS PR00046 Major sigma-70 factor signature 115 128 2.2E-24 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11140 bdff2efd831ca22329b0a9167263bc75 326 PRINTS PR00046 Major sigma-70 factor signature 139 147 2.2E-24 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11140 bdff2efd831ca22329b0a9167263bc75 326 PRINTS PR00046 Major sigma-70 factor signature 263 275 2.2E-24 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11140 bdff2efd831ca22329b0a9167263bc75 326 PRINTS PR00046 Major sigma-70 factor signature 284 299 2.2E-24 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11140 bdff2efd831ca22329b0a9167263bc75 326 PRINTS PR00046 Major sigma-70 factor signature 299 310 2.2E-24 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11140 bdff2efd831ca22329b0a9167263bc75 326 SUPERFAMILY SSF88659 223 317 1.87E-20 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11140 bdff2efd831ca22329b0a9167263bc75 326 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 284 310 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11140 bdff2efd831ca22329b0a9167263bc75 326 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 115 128 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11140 bdff2efd831ca22329b0a9167263bc75 326 TIGRFAM TIGR02394 rpoS_proteo: RNA polymerase sigma factor RpoS 46 325 1.6E-126 T 28-03-2018 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11140 bdff2efd831ca22329b0a9167263bc75 326 Pfam PF04545 Sigma-70, region 4 262 312 1.3E-14 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11140 bdff2efd831ca22329b0a9167263bc75 326 Pfam PF04539 Sigma-70 region 3 172 245 3.6E-17 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11140 bdff2efd831ca22329b0a9167263bc75 326 SUPERFAMILY SSF88946 53 161 3.14E-44 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS11140 bdff2efd831ca22329b0a9167263bc75 326 Gene3D G3DSA:1.10.10.10 254 321 5.6E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS17980 1f1152ee2ba9e1e196a3b6a07cea7cfb 344 Pfam PF01384 Phosphate transporter family 19 329 1.2E-76 T 28-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 MKLM6_RS00680 240e22a1570956be05502c3415283d54 264 SMART SM00850 156 260 3.3E-10 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MKLM6_RS00680 240e22a1570956be05502c3415283d54 264 Gene3D G3DSA:2.40.50.40 157 220 4.0E-8 T 28-03-2018 MKLM6_RS00680 240e22a1570956be05502c3415283d54 264 Pfam PF00072 Response regulator receiver domain 7 120 1.4E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS00680 240e22a1570956be05502c3415283d54 264 SMART SM00448 5 120 1.0E-13 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS00680 240e22a1570956be05502c3415283d54 264 Gene3D G3DSA:3.40.50.2300 2 156 2.0E-19 T 28-03-2018 MKLM6_RS00680 240e22a1570956be05502c3415283d54 264 SUPERFAMILY SSF52172 6 126 1.42E-20 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS00680 240e22a1570956be05502c3415283d54 264 Pfam PF04397 LytTr DNA-binding domain 160 259 7.3E-12 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MKLM6_RS01600 ab8dd68b3e681f551438c32190cf0720 213 PIRSF PIRSF000495 2 212 1.9E-69 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MKLM6_RS01600 ab8dd68b3e681f551438c32190cf0720 213 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 3 209 35.529 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MKLM6_RS01600 ab8dd68b3e681f551438c32190cf0720 213 SUPERFAMILY SSF52317 3 209 1.16E-56 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS01600 ab8dd68b3e681f551438c32190cf0720 213 Pfam PF00117 Glutamine amidotransferase class-I 6 207 4.1E-20 T 28-03-2018 IPR017926 Glutamine amidotransferase MKLM6_RS01600 ab8dd68b3e681f551438c32190cf0720 213 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 208 4.0E-65 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MKLM6_RS01600 ab8dd68b3e681f551438c32190cf0720 213 Gene3D G3DSA:3.40.50.880 1 210 5.1E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS13970 f57bd034793e311519de1ad5fbb86600 345 SUPERFAMILY SSF100950 9 332 1.38E-109 T 28-03-2018 MKLM6_RS13970 f57bd034793e311519de1ad5fbb86600 345 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 8 343 39.399 T 28-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 MKLM6_RS13970 f57bd034793e311519de1ad5fbb86600 345 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 10 331 1.1E-134 T 28-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 MKLM6_RS13970 f57bd034793e311519de1ad5fbb86600 345 Gene3D G3DSA:3.40.50.10470 140 336 1.4E-66 T 28-03-2018 MKLM6_RS13970 f57bd034793e311519de1ad5fbb86600 345 Pfam PF01008 Initiation factor 2 subunit family 51 331 2.5E-76 T 28-03-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 MKLM6_RS13970 f57bd034793e311519de1ad5fbb86600 345 Gene3D G3DSA:1.20.120.420 5 139 6.4E-43 T 28-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 MKLM6_RS13970 f57bd034793e311519de1ad5fbb86600 345 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 40 331 1.6E-108 T 28-03-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 MKLM6_RS15615 d827c8bfb4c5b9a799b751b7128ebc98 220 SUPERFAMILY SSF50630 57 155 2.74E-15 T 28-03-2018 IPR021109 Aspartic peptidase domain MKLM6_RS15615 d827c8bfb4c5b9a799b751b7128ebc98 220 TIGRFAM TIGR02281 clan_AA_DTGA: clan AA aspartic protease, TIGR02281 family 52 164 3.2E-20 T 28-03-2018 IPR011969 Clan AA aspartic peptidase, C-terminal MKLM6_RS15615 d827c8bfb4c5b9a799b751b7128ebc98 220 Pfam PF13975 gag-polyprotein putative aspartyl protease 66 150 4.4E-17 T 28-03-2018 MKLM6_RS15615 d827c8bfb4c5b9a799b751b7128ebc98 220 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 75 86 - T 28-03-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 MKLM6_RS15615 d827c8bfb4c5b9a799b751b7128ebc98 220 Gene3D G3DSA:2.40.70.10 55 163 1.1E-14 T 28-03-2018 IPR021109 Aspartic peptidase domain MKLM6_RS05195 90b6745aa0641721c87511a305899b0a 641 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 195 326 7.0E-45 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MKLM6_RS05195 90b6745aa0641721c87511a305899b0a 641 SMART SM00382 190 329 2.6E-25 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS05195 90b6745aa0641721c87511a305899b0a 641 SUPERFAMILY SSF52540 152 396 3.81E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS05195 90b6745aa0641721c87511a305899b0a 641 Pfam PF01434 Peptidase family M41 388 597 8.7E-82 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 MKLM6_RS05195 90b6745aa0641721c87511a305899b0a 641 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 103 599 3.0E-240 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 MKLM6_RS05195 90b6745aa0641721c87511a305899b0a 641 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 6 620 37.458 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 MKLM6_RS05195 90b6745aa0641721c87511a305899b0a 641 ProSitePatterns PS00674 AAA-protein family signature. 297 315 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 MKLM6_RS05195 90b6745aa0641721c87511a305899b0a 641 Gene3D G3DSA:1.10.8.60 339 420 9.5E-24 T 28-03-2018 MKLM6_RS05195 90b6745aa0641721c87511a305899b0a 641 SUPERFAMILY SSF140990 408 609 1.96E-75 T 28-03-2018 MKLM6_RS05195 90b6745aa0641721c87511a305899b0a 641 Pfam PF06480 FtsH Extracellular 9 96 6.5E-10 T 28-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 MKLM6_RS05195 90b6745aa0641721c87511a305899b0a 641 Gene3D G3DSA:3.40.50.300 138 338 4.4E-63 T 28-03-2018 MKLM6_RS19220 984028379ac5cafa7e3a724f2afd25e6 1035 SUPERFAMILY SSF82866 291 499 6.54E-35 T 28-03-2018 MKLM6_RS19220 984028379ac5cafa7e3a724f2afd25e6 1035 SUPERFAMILY SSF82714 185 267 4.58E-12 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS19220 984028379ac5cafa7e3a724f2afd25e6 1035 Gene3D G3DSA:3.30.70.1430 561 658 3.4E-7 T 28-03-2018 MKLM6_RS19220 984028379ac5cafa7e3a724f2afd25e6 1035 PRINTS PR00702 Acriflavin resistance protein family signature 333 356 4.0E-31 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS19220 984028379ac5cafa7e3a724f2afd25e6 1035 PRINTS PR00702 Acriflavin resistance protein family signature 546 563 4.0E-31 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS19220 984028379ac5cafa7e3a724f2afd25e6 1035 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 4.0E-31 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS19220 984028379ac5cafa7e3a724f2afd25e6 1035 PRINTS PR00702 Acriflavin resistance protein family signature 360 381 4.0E-31 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS19220 984028379ac5cafa7e3a724f2afd25e6 1035 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 4.0E-31 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS19220 984028379ac5cafa7e3a724f2afd25e6 1035 PRINTS PR00702 Acriflavin resistance protein family signature 388 412 4.0E-31 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS19220 984028379ac5cafa7e3a724f2afd25e6 1035 Gene3D G3DSA:3.30.2090.10 183 269 7.0E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS19220 984028379ac5cafa7e3a724f2afd25e6 1035 Gene3D G3DSA:3.30.70.1430 43 143 1.1E-19 T 28-03-2018 MKLM6_RS19220 984028379ac5cafa7e3a724f2afd25e6 1035 SUPERFAMILY SSF82866 798 1024 1.83E-37 T 28-03-2018 MKLM6_RS19220 984028379ac5cafa7e3a724f2afd25e6 1035 SUPERFAMILY SSF82714 715 798 3.66E-16 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS19220 984028379ac5cafa7e3a724f2afd25e6 1035 Pfam PF00873 AcrB/AcrD/AcrF family 6 1017 4.5E-222 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS19220 984028379ac5cafa7e3a724f2afd25e6 1035 SUPERFAMILY SSF82693 42 134 7.06E-18 T 28-03-2018 MKLM6_RS19220 984028379ac5cafa7e3a724f2afd25e6 1035 SUPERFAMILY SSF82693 269 312 3.82E-15 T 28-03-2018 MKLM6_RS19220 984028379ac5cafa7e3a724f2afd25e6 1035 SUPERFAMILY SSF82693 139 183 3.82E-15 T 28-03-2018 MKLM6_RS19220 984028379ac5cafa7e3a724f2afd25e6 1035 Gene3D G3DSA:3.30.2090.10 712 800 1.7E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS19220 984028379ac5cafa7e3a724f2afd25e6 1035 Gene3D G3DSA:1.20.1640.10 272 501 5.1E-34 T 28-03-2018 MKLM6_RS19220 984028379ac5cafa7e3a724f2afd25e6 1035 Gene3D G3DSA:1.20.1640.10 801 1023 2.6E-32 T 28-03-2018 MKLM6_RS19830 e89d450ce85b4453000dbc7359d4d5b6 312 SUPERFAMILY SSF53448 4 238 4.41E-38 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS19830 e89d450ce85b4453000dbc7359d4d5b6 312 Gene3D G3DSA:3.90.550.10 3 249 5.3E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS19830 e89d450ce85b4453000dbc7359d4d5b6 312 Pfam PF00535 Glycosyl transferase family 2 5 115 2.5E-22 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MKLM6_RS20765 4db94957da8513811890732f1439c9e3 200 Pfam PF00578 AhpC/TSA family 5 139 6.6E-34 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MKLM6_RS20765 4db94957da8513811890732f1439c9e3 200 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 160 194 1.2E-10 T 28-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MKLM6_RS20765 4db94957da8513811890732f1439c9e3 200 Gene3D G3DSA:3.40.30.10 4 161 6.6E-39 T 28-03-2018 MKLM6_RS20765 4db94957da8513811890732f1439c9e3 200 SUPERFAMILY SSF52833 3 196 9.47E-67 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS20765 4db94957da8513811890732f1439c9e3 200 Gene3D G3DSA:3.30.1020.10 162 199 2.5E-16 T 28-03-2018 MKLM6_RS20765 4db94957da8513811890732f1439c9e3 200 PIRSF PIRSF000239 1 199 6.3E-58 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MKLM6_RS17585 4bcfa06b18a177b6f60c32fc91d80bc2 297 Gene3D G3DSA:3.40.50.1000 150 297 8.6E-23 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS17585 4bcfa06b18a177b6f60c32fc91d80bc2 297 Pfam PF06189 5'-nucleotidase 35 295 1.3E-113 T 28-03-2018 IPR010394 5-nucleotidase GO:0000166|GO:0000287|GO:0005737|GO:0008253|GO:0009117 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821|Reactome: R-HSA-74259 MKLM6_RS06730 40a80bf8a8ad3b052c96f8509be42898 86 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 5 84 1.0E-38 T 28-03-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 MKLM6_RS06730 40a80bf8a8ad3b052c96f8509be42898 86 Gene3D G3DSA:3.30.2310.20 1 84 8.4E-27 T 28-03-2018 MKLM6_RS06730 40a80bf8a8ad3b052c96f8509be42898 86 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 5 84 1.0E-34 T 28-03-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 MKLM6_RS06730 40a80bf8a8ad3b052c96f8509be42898 86 SUPERFAMILY SSF143011 2 83 2.22E-28 T 28-03-2018 IPR035095 Toxin RelE-like domain MKLM6_RS03775 350b84fb9c95db97620e9ee9385f8386 180 Gene3D G3DSA:3.30.70.920 55 156 7.3E-13 T 28-03-2018 MKLM6_RS03775 350b84fb9c95db97620e9ee9385f8386 180 Pfam PF13404 AsnC-type helix-turn-helix domain 6 46 3.7E-8 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MKLM6_RS03775 350b84fb9c95db97620e9ee9385f8386 180 Gene3D G3DSA:1.10.10.10 2 54 1.2E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS03775 350b84fb9c95db97620e9ee9385f8386 180 SUPERFAMILY SSF46785 5 65 5.36E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS08855 f77525111b50bfd052219f19e9b8043a 323 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 18 322 3.3E-27 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 MKLM6_RS08855 f77525111b50bfd052219f19e9b8043a 323 SUPERFAMILY SSF51735 103 292 4.56E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS08855 f77525111b50bfd052219f19e9b8043a 323 SUPERFAMILY SSF52283 3 136 2.84E-35 T 28-03-2018 MKLM6_RS08855 f77525111b50bfd052219f19e9b8043a 323 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 202 224 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MKLM6_RS08855 f77525111b50bfd052219f19e9b8043a 323 Gene3D G3DSA:3.40.50.720 117 292 9.9E-52 T 28-03-2018 MKLM6_RS08855 f77525111b50bfd052219f19e9b8043a 323 Gene3D G3DSA:3.40.50.720 2 116 1.6E-31 T 28-03-2018 MKLM6_RS08855 f77525111b50bfd052219f19e9b8043a 323 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 291 1.0E-55 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MKLM6_RS08605 d76d4597ba17d5e2cbda6cfa623285fb 201 Gene3D G3DSA:3.90.1340.10 1 61 3.4E-20 T 28-03-2018 IPR011083 Phage tail collar domain MKLM6_RS08605 d76d4597ba17d5e2cbda6cfa623285fb 201 SUPERFAMILY SSF88874 8 194 5.75E-36 T 28-03-2018 MKLM6_RS08605 d76d4597ba17d5e2cbda6cfa623285fb 201 Gene3D G3DSA:4.10.1070.10 62 178 4.6E-5 T 28-03-2018 MKLM6_RS08605 d76d4597ba17d5e2cbda6cfa623285fb 201 Pfam PF07484 Phage Tail Collar Domain 13 68 8.3E-24 T 28-03-2018 IPR011083 Phage tail collar domain MKLM6_RS06160 1bc68d0c4efbe5f2df7538ff4d4a837e 287 Gene3D G3DSA:3.40.1360.10 183 286 3.1E-13 T 28-03-2018 MKLM6_RS06160 1bc68d0c4efbe5f2df7538ff4d4a837e 287 SMART SM00493 193 268 0.0014 T 28-03-2018 IPR006171 TOPRIM domain MKLM6_RS06160 1bc68d0c4efbe5f2df7538ff4d4a837e 287 Pfam PF13362 Toprim domain 195 285 1.6E-12 T 28-03-2018 IPR006171 TOPRIM domain MKLM6_RS05985 9ac356df4e74489bb44ed3b6f33e781b 243 Gene3D G3DSA:3.40.630.30 8 227 1.1E-41 T 28-03-2018 MKLM6_RS05985 9ac356df4e74489bb44ed3b6f33e781b 243 TIGRFAM TIGR03694 exosort_acyl: N-acyl amino acid synthase, PEP-CTERM/exosortase system-associated 7 215 1.0E-52 T 28-03-2018 IPR022484 PEP-CTERM/exosortase system-associated acyltransferase, predicted MKLM6_RS05985 9ac356df4e74489bb44ed3b6f33e781b 243 Pfam PF13444 Acetyltransferase (GNAT) domain 29 120 2.9E-15 T 28-03-2018 MKLM6_RS05985 9ac356df4e74489bb44ed3b6f33e781b 243 SUPERFAMILY SSF55729 11 207 4.61E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS05340 fc991a246bf34fc441c752c41eb9f195 468 SMART SM00479 8 172 6.2E-38 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MKLM6_RS05340 fc991a246bf34fc441c752c41eb9f195 468 SUPERFAMILY SSF53098 5 178 6.0E-51 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS05340 fc991a246bf34fc441c752c41eb9f195 468 SUPERFAMILY SSF82771 203 283 1.57E-12 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily MKLM6_RS05340 fc991a246bf34fc441c752c41eb9f195 468 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 11 169 5.9E-27 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS05340 fc991a246bf34fc441c752c41eb9f195 468 Gene3D G3DSA:3.40.1440.10 193 287 1.4E-17 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily MKLM6_RS05340 fc991a246bf34fc441c752c41eb9f195 468 Gene3D G3DSA:3.30.420.10 7 182 8.1E-40 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS05340 fc991a246bf34fc441c752c41eb9f195 468 Pfam PF00929 Exonuclease 11 158 3.6E-31 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MKLM6_RS05340 fc991a246bf34fc441c752c41eb9f195 468 SMART SM00465 203 284 1.2E-11 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily MKLM6_RS04525 1102d36663af1682a11e0d080b5f8aaf 716 SUPERFAMILY SSF90123 152 467 2.35E-53 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MKLM6_RS04525 1102d36663af1682a11e0d080b5f8aaf 716 SUPERFAMILY SSF52540 470 705 1.57E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS04525 1102d36663af1682a11e0d080b5f8aaf 716 Gene3D G3DSA:1.20.1560.10 151 470 5.6E-36 T 28-03-2018 MKLM6_RS04525 1102d36663af1682a11e0d080b5f8aaf 716 Pfam PF00005 ABC transporter 498 647 3.2E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS04525 1102d36663af1682a11e0d080b5f8aaf 716 SMART SM00382 507 693 5.1E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS04525 1102d36663af1682a11e0d080b5f8aaf 716 Pfam PF00664 ABC transporter transmembrane region 170 429 2.0E-26 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MKLM6_RS04525 1102d36663af1682a11e0d080b5f8aaf 716 Gene3D G3DSA:3.90.70.10 14 138 3.7E-15 T 28-03-2018 MKLM6_RS04525 1102d36663af1682a11e0d080b5f8aaf 716 Gene3D G3DSA:3.40.50.300 479 714 3.3E-66 T 28-03-2018 MKLM6_RS04525 1102d36663af1682a11e0d080b5f8aaf 716 TIGRFAM TIGR03375 type_I_sec_LssB: type I secretion system ATPase 17 711 2.9E-297 T 28-03-2018 IPR017750 ATPase, type I secretion system MKLM6_RS12905 001b0e0eccd630f2fa3ef89edc3e9ffc 552 Pfam PF00005 ABC transporter 353 493 3.9E-12 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS12905 001b0e0eccd630f2fa3ef89edc3e9ffc 552 Gene3D G3DSA:1.20.1560.10 3 323 6.5E-17 T 28-03-2018 MKLM6_RS12905 001b0e0eccd630f2fa3ef89edc3e9ffc 552 SUPERFAMILY SSF90123 9 320 1.07E-32 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MKLM6_RS12905 001b0e0eccd630f2fa3ef89edc3e9ffc 552 Gene3D G3DSA:3.40.50.300 338 550 3.7E-27 T 28-03-2018 MKLM6_RS12905 001b0e0eccd630f2fa3ef89edc3e9ffc 552 SUPERFAMILY SSF52540 352 546 8.39E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS12905 001b0e0eccd630f2fa3ef89edc3e9ffc 552 Pfam PF00664 ABC transporter transmembrane region 31 284 1.6E-6 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MKLM6_RS16410 16d58dc3fb6c2a123a9908b11595f9ad 161 Pfam PF02082 Transcriptional regulator 1 83 1.3E-28 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type MKLM6_RS16410 16d58dc3fb6c2a123a9908b11595f9ad 161 Gene3D G3DSA:1.10.10.10 1 141 4.4E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS16410 16d58dc3fb6c2a123a9908b11595f9ad 161 SUPERFAMILY SSF46785 2 132 7.49E-36 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS16410 16d58dc3fb6c2a123a9908b11595f9ad 161 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 130 1.6E-45 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type MKLM6_RS16410 16d58dc3fb6c2a123a9908b11595f9ad 161 TIGRFAM TIGR02010 IscR: iron-sulfur cluster assembly transcription factor IscR 1 132 1.3E-62 T 28-03-2018 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 MKLM6_RS20510 19aa69d482f1c6102f735377552a7064 360 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 358 24.608 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MKLM6_RS20510 19aa69d482f1c6102f735377552a7064 360 ProSitePatterns PS01348 MraY family signature 2. 189 200 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MKLM6_RS20510 19aa69d482f1c6102f735377552a7064 360 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 68 80 4.0E-5 T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MKLM6_RS20510 19aa69d482f1c6102f735377552a7064 360 Pfam PF00953 Glycosyl transferase family 4 99 283 6.3E-37 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 MKLM6_RS20510 19aa69d482f1c6102f735377552a7064 360 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 37 360 3.5E-140 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MKLM6_RS20510 19aa69d482f1c6102f735377552a7064 360 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MKLM6_RS09485 d98e8bb0b087232cad6733fb9798a523 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 28-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS09485 d98e8bb0b087232cad6733fb9798a523 65 Pfam PF01632 Ribosomal protein L35 2 62 2.3E-24 T 28-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS09485 d98e8bb0b087232cad6733fb9798a523 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.039 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MKLM6_RS09485 d98e8bb0b087232cad6733fb9798a523 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 6.7E-20 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MKLM6_RS09485 d98e8bb0b087232cad6733fb9798a523 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 6.7E-20 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MKLM6_RS09485 d98e8bb0b087232cad6733fb9798a523 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 6.7E-20 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MKLM6_RS09485 d98e8bb0b087232cad6733fb9798a523 65 SUPERFAMILY SSF143034 2 64 4.97E-23 T 28-03-2018 MKLM6_RS09485 d98e8bb0b087232cad6733fb9798a523 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 3.8E-25 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MKLM6_RS07245 b0b9780244e644ea825735908b2605ba 326 PRINTS PR00982 Lysyl-tRNA synthetase signature 209 225 5.5E-10 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MKLM6_RS07245 b0b9780244e644ea825735908b2605ba 326 PRINTS PR00982 Lysyl-tRNA synthetase signature 29 39 5.5E-10 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MKLM6_RS07245 b0b9780244e644ea825735908b2605ba 326 PRINTS PR00982 Lysyl-tRNA synthetase signature 95 112 5.5E-10 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MKLM6_RS07245 b0b9780244e644ea825735908b2605ba 326 PRINTS PR00982 Lysyl-tRNA synthetase signature 77 90 5.5E-10 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MKLM6_RS07245 b0b9780244e644ea825735908b2605ba 326 SUPERFAMILY SSF55681 11 323 2.01E-71 T 28-03-2018 MKLM6_RS07245 b0b9780244e644ea825735908b2605ba 326 TIGRFAM TIGR00462 genX: EF-P lysine aminoacylase GenX 14 321 8.7E-112 T 28-03-2018 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 MKLM6_RS07245 b0b9780244e644ea825735908b2605ba 326 Pfam PF00152 tRNA synthetases class II (D, K and N) 207 323 3.1E-23 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS07245 b0b9780244e644ea825735908b2605ba 326 Pfam PF00152 tRNA synthetases class II (D, K and N) 12 135 1.2E-17 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS07245 b0b9780244e644ea825735908b2605ba 326 Gene3D G3DSA:3.30.930.10 6 326 4.9E-61 T 28-03-2018 MKLM6_RS09065 4c2cf6414f73aa74fc42d721b4ae896d 298 Pfam PF08443 RimK-like ATP-grasp domain 103 287 1.5E-23 T 28-03-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 MKLM6_RS09065 4c2cf6414f73aa74fc42d721b4ae896d 298 Gene3D G3DSA:3.30.470.20 177 280 2.3E-25 T 28-03-2018 MKLM6_RS09065 4c2cf6414f73aa74fc42d721b4ae896d 298 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 77 286 9.8E-46 T 28-03-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 MKLM6_RS09065 4c2cf6414f73aa74fc42d721b4ae896d 298 SUPERFAMILY SSF56059 110 292 1.25E-37 T 28-03-2018 MKLM6_RS09065 4c2cf6414f73aa74fc42d721b4ae896d 298 Gene3D G3DSA:3.30.1490.20 107 176 4.9E-9 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MKLM6_RS09065 4c2cf6414f73aa74fc42d721b4ae896d 298 Gene3D G3DSA:3.40.50.20 3 106 3.2E-21 T 28-03-2018 MKLM6_RS14525 ba2e9cd14d946fc486fda6b7082310a8 628 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 69 118 1.1E-7 T 28-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS14525 ba2e9cd14d946fc486fda6b7082310a8 628 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 317 329 1.2E-21 T 28-03-2018 MKLM6_RS14525 ba2e9cd14d946fc486fda6b7082310a8 628 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 81 106 1.2E-21 T 28-03-2018 MKLM6_RS14525 ba2e9cd14d946fc486fda6b7082310a8 628 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 249 275 1.2E-21 T 28-03-2018 MKLM6_RS14525 ba2e9cd14d946fc486fda6b7082310a8 628 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 227 248 1.2E-21 T 28-03-2018 MKLM6_RS14525 ba2e9cd14d946fc486fda6b7082310a8 628 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 109 129 1.2E-21 T 28-03-2018 MKLM6_RS14525 ba2e9cd14d946fc486fda6b7082310a8 628 Pfam PF00361 Proton-conducting membrane transporter 455 596 6.6E-6 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS14525 ba2e9cd14d946fc486fda6b7082310a8 628 Pfam PF00361 Proton-conducting membrane transporter 136 354 3.9E-34 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS00660 6506f2f56c1a094f759531cf7f20f667 611 Pfam PF13522 Glutamine amidotransferase domain 63 186 1.6E-21 T 28-03-2018 MKLM6_RS00660 6506f2f56c1a094f759531cf7f20f667 611 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 611 3.9E-257 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 MKLM6_RS00660 6506f2f56c1a094f759531cf7f20f667 611 Pfam PF01380 SIS domain 462 593 2.2E-27 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MKLM6_RS00660 6506f2f56c1a094f759531cf7f20f667 611 Pfam PF01380 SIS domain 293 419 7.3E-34 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MKLM6_RS00660 6506f2f56c1a094f759531cf7f20f667 611 Gene3D G3DSA:3.40.50.10490 459 609 3.1E-50 T 28-03-2018 MKLM6_RS00660 6506f2f56c1a094f759531cf7f20f667 611 Gene3D G3DSA:3.40.50.10490 239 458 2.2E-63 T 28-03-2018 MKLM6_RS00660 6506f2f56c1a094f759531cf7f20f667 611 SUPERFAMILY SSF53697 245 611 2.04E-111 T 28-03-2018 MKLM6_RS00660 6506f2f56c1a094f759531cf7f20f667 611 SUPERFAMILY SSF56235 2 234 5.06E-74 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MKLM6_RS00660 6506f2f56c1a094f759531cf7f20f667 611 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 611 40.152 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 MKLM6_RS00660 6506f2f56c1a094f759531cf7f20f667 611 Gene3D G3DSA:3.60.20.10 2 238 4.9E-64 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MKLM6_RS18020 0e1b661951345a09ece44f7c02c3b9da 283 PRINTS PR00207 Flagellin signature 37 54 1.8E-21 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MKLM6_RS18020 0e1b661951345a09ece44f7c02c3b9da 283 PRINTS PR00207 Flagellin signature 112 135 1.8E-21 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MKLM6_RS18020 0e1b661951345a09ece44f7c02c3b9da 283 PRINTS PR00207 Flagellin signature 76 95 1.8E-21 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MKLM6_RS18020 0e1b661951345a09ece44f7c02c3b9da 283 Gene3D G3DSA:1.20.1330.10 40 255 1.8E-70 T 28-03-2018 MKLM6_RS18020 0e1b661951345a09ece44f7c02c3b9da 283 Pfam PF00700 Bacterial flagellin C-terminal helical region 197 282 1.2E-26 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MKLM6_RS18020 0e1b661951345a09ece44f7c02c3b9da 283 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 142 2.0E-40 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MKLM6_RS18020 0e1b661951345a09ece44f7c02c3b9da 283 SUPERFAMILY SSF64518 1 283 3.14E-88 T 28-03-2018 MKLM6_RS18870 46e573c60d753a666a7d8bf02eee5d93 347 Gene3D G3DSA:3.30.420.40 256 321 2.1E-9 T 28-03-2018 MKLM6_RS18870 46e573c60d753a666a7d8bf02eee5d93 347 Pfam PF06723 MreB/Mbl protein 11 338 1.1E-145 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MKLM6_RS18870 46e573c60d753a666a7d8bf02eee5d93 347 SUPERFAMILY SSF53067 154 338 5.38E-48 T 28-03-2018 MKLM6_RS18870 46e573c60d753a666a7d8bf02eee5d93 347 Gene3D G3DSA:3.30.420.40 8 163 2.4E-39 T 28-03-2018 MKLM6_RS18870 46e573c60d753a666a7d8bf02eee5d93 347 SUPERFAMILY SSF53067 9 152 3.24E-36 T 28-03-2018 MKLM6_RS18870 46e573c60d753a666a7d8bf02eee5d93 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 304 330 1.1E-63 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MKLM6_RS18870 46e573c60d753a666a7d8bf02eee5d93 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 52 70 1.1E-63 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MKLM6_RS18870 46e573c60d753a666a7d8bf02eee5d93 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 72 95 1.1E-63 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MKLM6_RS18870 46e573c60d753a666a7d8bf02eee5d93 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 136 155 1.1E-63 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MKLM6_RS18870 46e573c60d753a666a7d8bf02eee5d93 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 191 211 1.1E-63 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MKLM6_RS18870 46e573c60d753a666a7d8bf02eee5d93 347 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 338 3.0E-157 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MKLM6_RS18870 46e573c60d753a666a7d8bf02eee5d93 347 Gene3D G3DSA:3.90.640.10 198 255 6.8E-27 T 28-03-2018 MKLM6_RS18870 46e573c60d753a666a7d8bf02eee5d93 347 Gene3D G3DSA:3.30.420.40 164 197 0.013 T 28-03-2018 MKLM6_RS08165 0aace0eb227d2910f111b99ad8512e7e 976 Pfam PF07715 TonB-dependent Receptor Plug Domain 160 262 4.7E-10 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS08165 0aace0eb227d2910f111b99ad8512e7e 976 Gene3D G3DSA:2.40.170.20 278 976 4.5E-46 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS08165 0aace0eb227d2910f111b99ad8512e7e 976 Gene3D G3DSA:2.170.130.10 137 277 3.0E-18 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS08165 0aace0eb227d2910f111b99ad8512e7e 976 SUPERFAMILY SSF56935 419 608 8.42E-72 T 28-03-2018 MKLM6_RS08165 0aace0eb227d2910f111b99ad8512e7e 976 SUPERFAMILY SSF56935 696 976 8.42E-72 T 28-03-2018 MKLM6_RS08165 0aace0eb227d2910f111b99ad8512e7e 976 SUPERFAMILY SSF56935 138 386 8.42E-72 T 28-03-2018 MKLM6_RS00155 b74bd0fc61dcf0bbc028803574d95222 335 SUPERFAMILY SSF52980 29 217 4.08E-32 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MKLM6_RS00155 b74bd0fc61dcf0bbc028803574d95222 335 TIGRFAM TIGR03033 phage_rel_nuc: putative phage-type endonuclease 24 183 1.9E-46 T 28-03-2018 IPR017482 Putative phage-type endonuclease MKLM6_RS00155 b74bd0fc61dcf0bbc028803574d95222 335 Gene3D G3DSA:3.90.320.10 27 237 6.0E-44 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 MKLM6_RS00155 b74bd0fc61dcf0bbc028803574d95222 335 Pfam PF09588 YqaJ-like viral recombinase domain 30 172 2.9E-35 T 28-03-2018 IPR019080 YqaJ viral recombinase MKLM6_RS05690 1a04f14946e8ef1fb952fbe5c4c8a3d4 172 Pfam PF01797 Transposase IS200 like 14 126 4.2E-10 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS05690 1a04f14946e8ef1fb952fbe5c4c8a3d4 172 SUPERFAMILY SSF143422 1 133 1.2E-36 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS05690 1a04f14946e8ef1fb952fbe5c4c8a3d4 172 SMART SM01321 9 127 2.5E-38 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS05690 1a04f14946e8ef1fb952fbe5c4c8a3d4 172 Gene3D G3DSA:3.30.70.1290 1 135 1.9E-37 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS13200 76c6376fca0d8163052d3101894a603f 454 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 3 453 7.7E-116 T 28-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 MKLM6_RS13200 76c6376fca0d8163052d3101894a603f 454 Pfam PF02163 Peptidase family M50 9 440 8.1E-80 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 MKLM6_RS13200 76c6376fca0d8163052d3101894a603f 454 Gene3D G3DSA:2.30.42.10 221 309 8.1E-16 T 28-03-2018 MKLM6_RS13200 76c6376fca0d8163052d3101894a603f 454 SUPERFAMILY SSF50156 211 289 1.28E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 MKLM6_RS13200 76c6376fca0d8163052d3101894a603f 454 SMART SM00228 115 188 5.9E-5 T 28-03-2018 IPR001478 PDZ domain GO:0005515 MKLM6_RS13200 76c6376fca0d8163052d3101894a603f 454 SMART SM00228 192 280 0.041 T 28-03-2018 IPR001478 PDZ domain GO:0005515 MKLM6_RS13200 76c6376fca0d8163052d3101894a603f 454 Gene3D G3DSA:2.30.42.10 27 205 5.9E-11 T 28-03-2018 MKLM6_RS13200 76c6376fca0d8163052d3101894a603f 454 SUPERFAMILY SSF50156 89 179 3.68E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 MKLM6_RS21650 c35fe9069d0dde3ebda527d2a0aa5431 300 Pfam PF03466 LysR substrate binding domain 88 292 7.5E-48 T 28-03-2018 IPR005119 LysR, substrate-binding MKLM6_RS21650 c35fe9069d0dde3ebda527d2a0aa5431 300 SUPERFAMILY SSF46785 4 87 2.5E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS21650 c35fe9069d0dde3ebda527d2a0aa5431 300 Gene3D G3DSA:3.40.190.10 176 263 3.6E-24 T 28-03-2018 MKLM6_RS21650 c35fe9069d0dde3ebda527d2a0aa5431 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.5E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS21650 c35fe9069d0dde3ebda527d2a0aa5431 300 SUPERFAMILY SSF53850 89 294 5.07E-46 T 28-03-2018 MKLM6_RS21650 c35fe9069d0dde3ebda527d2a0aa5431 300 Gene3D G3DSA:1.10.10.10 3 90 4.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS21650 c35fe9069d0dde3ebda527d2a0aa5431 300 Gene3D G3DSA:3.40.190.10 91 175 5.6E-13 T 28-03-2018 MKLM6_RS03950 56bbc19cf9c4aa43180ca92cb48c1150 279 Pfam PF00571 CBS domain 131 185 3.9E-5 T 28-03-2018 IPR000644 CBS domain MKLM6_RS03950 56bbc19cf9c4aa43180ca92cb48c1150 279 Pfam PF00571 CBS domain 66 121 2.3E-6 T 28-03-2018 IPR000644 CBS domain MKLM6_RS03950 56bbc19cf9c4aa43180ca92cb48c1150 279 SUPERFAMILY SSF54631 63 196 3.41E-32 T 28-03-2018 MKLM6_RS03950 56bbc19cf9c4aa43180ca92cb48c1150 279 Pfam PF03471 Transporter associated domain 203 278 4.1E-22 T 28-03-2018 IPR005170 Transporter-associated domain MKLM6_RS03950 56bbc19cf9c4aa43180ca92cb48c1150 279 SMART SM00116 75 124 7.7E-4 T 28-03-2018 IPR000644 CBS domain MKLM6_RS03950 56bbc19cf9c4aa43180ca92cb48c1150 279 SMART SM00116 137 185 0.25 T 28-03-2018 IPR000644 CBS domain MKLM6_RS03950 56bbc19cf9c4aa43180ca92cb48c1150 279 SMART SM01091 202 279 1.1E-27 T 28-03-2018 IPR005170 Transporter-associated domain MKLM6_RS03950 56bbc19cf9c4aa43180ca92cb48c1150 279 Gene3D G3DSA:3.30.465.10 192 278 4.7E-26 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MKLM6_RS03950 56bbc19cf9c4aa43180ca92cb48c1150 279 SUPERFAMILY SSF56176 200 277 6.0E-23 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MKLM6_RS03950 56bbc19cf9c4aa43180ca92cb48c1150 279 Gene3D G3DSA:3.10.580.10 45 191 1.7E-33 T 28-03-2018 MKLM6_RS18480 cd3b4c8e7c7a6f582e3bfec7b9c58edd 123 Gene3D G3DSA:3.30.1390.10 53 123 1.3E-31 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MKLM6_RS18480 cd3b4c8e7c7a6f582e3bfec7b9c58edd 123 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 58 97 2.0E-11 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18480 cd3b4c8e7c7a6f582e3bfec7b9c58edd 123 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 123 1.5E-48 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18480 cd3b4c8e7c7a6f582e3bfec7b9c58edd 123 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 49 6.1E-18 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18480 cd3b4c8e7c7a6f582e3bfec7b9c58edd 123 SUPERFAMILY SSF48300 4 59 4.05E-18 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18480 cd3b4c8e7c7a6f582e3bfec7b9c58edd 123 SUPERFAMILY SSF54736 52 123 1.5E-25 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MKLM6_RS18480 cd3b4c8e7c7a6f582e3bfec7b9c58edd 123 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 123 25.274 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18480 cd3b4c8e7c7a6f582e3bfec7b9c58edd 123 Gene3D G3DSA:1.20.5.710 2 52 3.9E-15 T 28-03-2018 MKLM6_RS18480 cd3b4c8e7c7a6f582e3bfec7b9c58edd 123 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 57 123 3.6E-31 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS12020 c6ecf49481086070cb50ad8e642db952 932 Gene3D G3DSA:3.30.460.10 99 193 1.5E-4 T 28-03-2018 MKLM6_RS12020 c6ecf49481086070cb50ad8e642db952 932 Pfam PF01295 Adenylate cyclase, class-I 243 808 1.9E-108 T 28-03-2018 IPR000274 Adenylate cyclase, class-I GO:0004016|GO:0006171 KEGG: 00230+4.6.1.1 MKLM6_RS12020 c6ecf49481086070cb50ad8e642db952 932 Pfam PF12633 Adenylate cyclase NT domain 22 216 3.6E-69 T 28-03-2018 IPR024685 Adenylate cyclase class-I, N-terminal domain KEGG: 00230+4.6.1.1 MKLM6_RS12020 c6ecf49481086070cb50ad8e642db952 932 PIRSF PIRSF001444 18 909 2.9E-176 T 28-03-2018 IPR000274 Adenylate cyclase, class-I GO:0004016|GO:0006171 KEGG: 00230+4.6.1.1 MKLM6_RS14050 3898c3d0a5526bb64a75448e510bd4b9 547 Gene3D G3DSA:3.40.720.10 312 546 1.2E-26 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MKLM6_RS14050 3898c3d0a5526bb64a75448e510bd4b9 547 Gene3D G3DSA:3.40.1450.10 88 311 1.6E-75 T 28-03-2018 MKLM6_RS14050 3898c3d0a5526bb64a75448e510bd4b9 547 SUPERFAMILY SSF64158 88 322 3.4E-63 T 28-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MKLM6_RS14050 3898c3d0a5526bb64a75448e510bd4b9 547 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 94 313 4.6E-64 T 28-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MKLM6_RS14050 3898c3d0a5526bb64a75448e510bd4b9 547 Pfam PF01676 Metalloenzyme superfamily 15 534 2.0E-70 T 28-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 MKLM6_RS14050 3898c3d0a5526bb64a75448e510bd4b9 547 SUPERFAMILY SSF53649 327 540 8.46E-54 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MKLM6_RS14050 3898c3d0a5526bb64a75448e510bd4b9 547 SUPERFAMILY SSF53649 15 88 8.46E-54 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MKLM6_RS14050 3898c3d0a5526bb64a75448e510bd4b9 547 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 15 540 8.8E-131 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MKLM6_RS14050 3898c3d0a5526bb64a75448e510bd4b9 547 PIRSF PIRSF001492 10 546 7.8E-175 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MKLM6_RS05655 e9a890092e3816921878a28a18dfd4ad 370 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 1 362 55.824 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MKLM6_RS05655 e9a890092e3816921878a28a18dfd4ad 370 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 3 364 4.3E-168 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MKLM6_RS05655 e9a890092e3816921878a28a18dfd4ad 370 Pfam PF01702 Queuine tRNA-ribosyltransferase 126 359 2.6E-92 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MKLM6_RS05655 e9a890092e3816921878a28a18dfd4ad 370 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 3 362 1.7E-162 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MKLM6_RS05655 e9a890092e3816921878a28a18dfd4ad 370 SUPERFAMILY SSF51713 1 361 1.31E-160 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MKLM6_RS05655 e9a890092e3816921878a28a18dfd4ad 370 Gene3D G3DSA:3.20.20.105 1 365 3.6E-158 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MKLM6_RS02400 41f7d48d7b5bc40b0629801fe6ea43ed 921 SMART SM00487 157 375 1.9E-19 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MKLM6_RS02400 41f7d48d7b5bc40b0629801fe6ea43ed 921 SUPERFAMILY SSF52540 466 558 2.28E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS02400 41f7d48d7b5bc40b0629801fe6ea43ed 921 SUPERFAMILY SSF52540 182 220 2.28E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS02400 41f7d48d7b5bc40b0629801fe6ea43ed 921 Pfam PF04851 Type III restriction enzyme, res subunit 161 347 4.2E-40 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MKLM6_RS02400 41f7d48d7b5bc40b0629801fe6ea43ed 921 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 4 121 2.0E-7 T 28-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 MKLM6_RS02400 41f7d48d7b5bc40b0629801fe6ea43ed 921 Pfam PF08463 EcoEI R protein C-terminal 741 919 1.6E-47 T 28-03-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 MKLM6_RS02400 41f7d48d7b5bc40b0629801fe6ea43ed 921 SUPERFAMILY SSF52540 146 273 2.72E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS02400 41f7d48d7b5bc40b0629801fe6ea43ed 921 SUPERFAMILY SSF52540 304 378 2.72E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS02400 41f7d48d7b5bc40b0629801fe6ea43ed 921 Gene3D G3DSA:3.40.50.300 413 563 4.3E-8 T 28-03-2018 MKLM6_RS02400 41f7d48d7b5bc40b0629801fe6ea43ed 921 Gene3D G3DSA:3.40.50.300 130 368 1.0E-29 T 28-03-2018 MKLM6_RS11370 2f90e80d54bb50f2c8bf1e63610061f5 141 Pfam PF08334 Type II secretion system (T2SS), protein G 33 140 2.3E-44 T 28-03-2018 IPR013545 Type II secretion system protein G MKLM6_RS11370 2f90e80d54bb50f2c8bf1e63610061f5 141 PRINTS PR00813 Bacterial general secretion pathway protein G signature 10 35 1.0E-14 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 MKLM6_RS11370 2f90e80d54bb50f2c8bf1e63610061f5 141 PRINTS PR00813 Bacterial general secretion pathway protein G signature 46 64 1.0E-14 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 MKLM6_RS11370 2f90e80d54bb50f2c8bf1e63610061f5 141 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 9 141 4.5E-51 T 28-03-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 MKLM6_RS11370 2f90e80d54bb50f2c8bf1e63610061f5 141 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 30 6.8E-8 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS11370 2f90e80d54bb50f2c8bf1e63610061f5 141 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS11370 2f90e80d54bb50f2c8bf1e63610061f5 141 SUPERFAMILY SSF54523 37 141 6.28E-36 T 28-03-2018 MKLM6_RS11370 2f90e80d54bb50f2c8bf1e63610061f5 141 Pfam PF07963 Prokaryotic N-terminal methylation motif 6 30 9.6E-9 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS11370 2f90e80d54bb50f2c8bf1e63610061f5 141 Gene3D G3DSA:3.30.700.10 25 140 1.3E-26 T 28-03-2018 MKLM6_RS21040 2102fdcbb0c531b69a640747de018778 167 Pfam PF08281 Sigma-70, region 4 108 159 1.8E-16 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS21040 2102fdcbb0c531b69a640747de018778 167 SUPERFAMILY SSF88659 103 164 1.05E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS21040 2102fdcbb0c531b69a640747de018778 167 SUPERFAMILY SSF88946 4 88 1.02E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS21040 2102fdcbb0c531b69a640747de018778 167 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 161 6.6E-25 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS21040 2102fdcbb0c531b69a640747de018778 167 Gene3D G3DSA:1.10.1740.10 1 77 6.6E-12 T 28-03-2018 MKLM6_RS21040 2102fdcbb0c531b69a640747de018778 167 Pfam PF04542 Sigma-70 region 2 11 74 1.9E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS21040 2102fdcbb0c531b69a640747de018778 167 Gene3D G3DSA:1.10.10.10 87 167 4.8E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS08990 27dfe94aec3b4572830c0dae7777ee46 1034 Gene3D G3DSA:1.20.5.550 8 54 1.5E-4 T 28-03-2018 IPR024090 Proline dehydrogenase PutA, domain I GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MKLM6_RS08990 27dfe94aec3b4572830c0dae7777ee46 1034 SUPERFAMILY SSF51730 182 508 2.0E-102 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like MKLM6_RS08990 27dfe94aec3b4572830c0dae7777ee46 1034 PIRSF PIRSF000197 2 1025 0.0 T 28-03-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MKLM6_RS08990 27dfe94aec3b4572830c0dae7777ee46 1034 Pfam PF01619 Proline dehydrogenase 188 474 1.0E-93 T 28-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 MKLM6_RS08990 27dfe94aec3b4572830c0dae7777ee46 1034 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 62 172 1.7E-34 T 28-03-2018 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MKLM6_RS08990 27dfe94aec3b4572830c0dae7777ee46 1034 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 506 1011 1.1E-188 T 28-03-2018 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MKLM6_RS08990 27dfe94aec3b4572830c0dae7777ee46 1034 Gene3D G3DSA:3.20.20.220 93 505 4.2E-96 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like MKLM6_RS08990 27dfe94aec3b4572830c0dae7777ee46 1034 SUPERFAMILY SSF53720 526 1019 1.7E-118 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MKLM6_RS08990 27dfe94aec3b4572830c0dae7777ee46 1034 Pfam PF00171 Aldehyde dehydrogenase family 558 1014 8.6E-110 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MKLM6_RS08990 27dfe94aec3b4572830c0dae7777ee46 1034 SUPERFAMILY SSF81935 7 174 5.89E-43 T 28-03-2018 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MKLM6_RS08990 27dfe94aec3b4572830c0dae7777ee46 1034 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 816 827 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 MKLM6_RS08990 27dfe94aec3b4572830c0dae7777ee46 1034 Gene3D G3DSA:3.40.605.10 531 804 1.1E-67 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MKLM6_RS08990 27dfe94aec3b4572830c0dae7777ee46 1034 Gene3D G3DSA:3.40.309.10 805 995 3.8E-42 T 28-03-2018 MKLM6_RS04010 283c3dec2a61aedebdcbf3e2ba2af840 293 Gene3D G3DSA:3.55.30.10 1 173 6.7E-47 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 MKLM6_RS04010 283c3dec2a61aedebdcbf3e2ba2af840 293 Hamap MF_00117 33 kDa chaperonin [hslO]. 4 281 28.293 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 MKLM6_RS04010 283c3dec2a61aedebdcbf3e2ba2af840 293 SUPERFAMILY SSF118352 223 279 1.96E-18 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 MKLM6_RS04010 283c3dec2a61aedebdcbf3e2ba2af840 293 Gene3D G3DSA:3.90.1280.10 223 278 6.6E-22 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 MKLM6_RS04010 283c3dec2a61aedebdcbf3e2ba2af840 293 Pfam PF01430 Hsp33 protein 5 270 5.9E-78 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 MKLM6_RS04010 283c3dec2a61aedebdcbf3e2ba2af840 293 SUPERFAMILY SSF64397 5 229 2.09E-59 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 MKLM6_RS04010 283c3dec2a61aedebdcbf3e2ba2af840 293 PIRSF PIRSF005261 1 281 7.1E-71 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 MKLM6_RS04010 283c3dec2a61aedebdcbf3e2ba2af840 293 Gene3D G3DSA:1.10.287.480 178 222 7.7E-20 T 28-03-2018 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain MKLM6_RS15810 d36fc16758ffdfd90c05d4fef01047bc 298 SUPERFAMILY SSF53448 4 132 5.28E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS15810 d36fc16758ffdfd90c05d4fef01047bc 298 Gene3D G3DSA:3.90.550.10 2 263 2.6E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS15810 d36fc16758ffdfd90c05d4fef01047bc 298 Pfam PF00535 Glycosyl transferase family 2 5 129 6.1E-23 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MKLM6_RS02895 669305e58a6e8a70553b83a57ec2355d 288 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 34 277 9.4E-89 T 28-03-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 MKLM6_RS02895 669305e58a6e8a70553b83a57ec2355d 288 SUPERFAMILY SSF53335 9 275 1.02E-87 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS02895 669305e58a6e8a70553b83a57ec2355d 288 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 2 266 40.113 T 28-03-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 MKLM6_RS02895 669305e58a6e8a70553b83a57ec2355d 288 Gene3D G3DSA:3.40.50.150 1 287 1.1E-79 T 28-03-2018 MKLM6_RS07795 9d32403f6dff57efffcc5fb369976402 515 SMART SM00917 370 506 1.2E-4 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MKLM6_RS07795 9d32403f6dff57efffcc5fb369976402 515 Pfam PF00682 HMGL-like 8 275 3.8E-50 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MKLM6_RS07795 9d32403f6dff57efffcc5fb369976402 515 SUPERFAMILY SSF51569 5 292 6.59E-68 T 28-03-2018 MKLM6_RS07795 9d32403f6dff57efffcc5fb369976402 515 SUPERFAMILY SSF110921 392 503 1.57E-9 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MKLM6_RS07795 9d32403f6dff57efffcc5fb369976402 515 Pfam PF08502 LeuA allosteric (dimerisation) domain 371 503 2.3E-16 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MKLM6_RS07795 9d32403f6dff57efffcc5fb369976402 515 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 15 31 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MKLM6_RS07795 9d32403f6dff57efffcc5fb369976402 515 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 204 217 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MKLM6_RS07795 9d32403f6dff57efffcc5fb369976402 515 Gene3D G3DSA:3.20.20.70 7 325 2.3E-80 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS13750 045a321585c8bd047ac518499598f7a4 580 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 29 579 1.3E-109 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MKLM6_RS13750 045a321585c8bd047ac518499598f7a4 580 Pfam PF01514 Secretory protein of YscJ/FliF family 45 235 1.6E-68 T 28-03-2018 IPR006182 Secretory protein YscJ/FliF MKLM6_RS13750 045a321585c8bd047ac518499598f7a4 580 PIRSF PIRSF004862 16 580 4.0E-149 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MKLM6_RS13750 045a321585c8bd047ac518499598f7a4 580 PRINTS PR01009 Flagellar M-ring protein signature 211 229 9.8E-34 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MKLM6_RS13750 045a321585c8bd047ac518499598f7a4 580 PRINTS PR01009 Flagellar M-ring protein signature 281 299 9.8E-34 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MKLM6_RS13750 045a321585c8bd047ac518499598f7a4 580 PRINTS PR01009 Flagellar M-ring protein signature 136 154 9.8E-34 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MKLM6_RS13750 045a321585c8bd047ac518499598f7a4 580 PRINTS PR01009 Flagellar M-ring protein signature 361 385 9.8E-34 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MKLM6_RS13750 045a321585c8bd047ac518499598f7a4 580 PRINTS PR01009 Flagellar M-ring protein signature 168 182 9.8E-34 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MKLM6_RS13750 045a321585c8bd047ac518499598f7a4 580 Gene3D G3DSA:3.30.70.1530 66 128 1.2E-7 T 28-03-2018 MKLM6_RS13750 045a321585c8bd047ac518499598f7a4 580 Pfam PF08345 Flagellar M-ring protein C-terminal 268 437 8.9E-48 T 28-03-2018 IPR013556 Flagellar M-ring C-terminal MKLM6_RS13855 9478c479d52e61298916392d6db0e984 379 SUPERFAMILY SSF51419 19 249 1.16E-35 T 28-03-2018 IPR029066 PLP-binding barrel MKLM6_RS13855 9478c479d52e61298916392d6db0e984 379 Gene3D G3DSA:2.40.37.10 238 374 1.3E-24 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MKLM6_RS13855 9478c479d52e61298916392d6db0e984 379 SUPERFAMILY SSF50621 219 356 3.56E-25 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MKLM6_RS13855 9478c479d52e61298916392d6db0e984 379 PIRSF PIRSF038941 2 375 6.7E-106 T 28-03-2018 IPR005730 Carboxynorspermidine decarboxylase GO:0016831|GO:0045312 KEGG: 00330+4.1.1.96|MetaCyc: PWY-6562 MKLM6_RS13855 9478c479d52e61298916392d6db0e984 379 Gene3D G3DSA:3.20.20.10 20 237 1.2E-33 T 28-03-2018 IPR029066 PLP-binding barrel MKLM6_RS13855 9478c479d52e61298916392d6db0e984 379 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 38 245 2.8E-6 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 MKLM6_RS13855 9478c479d52e61298916392d6db0e984 379 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 132 333 2.0E-8 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 MKLM6_RS13855 9478c479d52e61298916392d6db0e984 379 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 236 255 9.4E-8 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MKLM6_RS13855 9478c479d52e61298916392d6db0e984 379 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 333 346 9.4E-8 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MKLM6_RS13855 9478c479d52e61298916392d6db0e984 379 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 63 75 9.4E-8 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MKLM6_RS18130 afce5b647afeadaba0a0664d974e49e2 394 Gene3D G3DSA:3.40.50.300 222 370 1.0E-42 T 28-03-2018 MKLM6_RS18130 afce5b647afeadaba0a0664d974e49e2 394 SMART SM00490 259 340 7.3E-31 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS18130 afce5b647afeadaba0a0664d974e49e2 394 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 154 162 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MKLM6_RS18130 afce5b647afeadaba0a0664d974e49e2 394 Gene3D G3DSA:3.40.50.300 7 221 8.9E-58 T 28-03-2018 MKLM6_RS18130 afce5b647afeadaba0a0664d974e49e2 394 Pfam PF00270 DEAD/DEAH box helicase 25 196 1.4E-48 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MKLM6_RS18130 afce5b647afeadaba0a0664d974e49e2 394 SMART SM00487 20 223 3.4E-60 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MKLM6_RS18130 afce5b647afeadaba0a0664d974e49e2 394 Pfam PF00271 Helicase conserved C-terminal domain 236 340 1.4E-26 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS18130 afce5b647afeadaba0a0664d974e49e2 394 SUPERFAMILY SSF52540 73 358 8.05E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS02530 91ba88f4e0d1ddbd3c70df770103ce34 347 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 2 345 2.4E-95 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MKLM6_RS02530 91ba88f4e0d1ddbd3c70df770103ce34 347 SUPERFAMILY SSF102114 103 308 6.8E-12 T 28-03-2018 MKLM6_RS02530 91ba88f4e0d1ddbd3c70df770103ce34 347 Pfam PF04055 Radical SAM superfamily 107 272 8.1E-10 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS02530 91ba88f4e0d1ddbd3c70df770103ce34 347 Gene3D G3DSA:3.20.20.70 55 323 2.2E-29 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS02530 91ba88f4e0d1ddbd3c70df770103ce34 347 PIRSF PIRSF006004 2 347 1.2E-105 T 28-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MKLM6_RS17635 1ebb30a8329139ccbdcca130538ea96a 157 PIRSF PIRSF000216 1 157 1.0E-46 T 28-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS17635 1ebb30a8329139ccbdcca130538ea96a 157 SUPERFAMILY SSF52833 9 156 1.05E-46 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS17635 1ebb30a8329139ccbdcca130538ea96a 157 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 13 154 7.0E-43 T 28-03-2018 MKLM6_RS17635 1ebb30a8329139ccbdcca130538ea96a 157 Gene3D G3DSA:3.40.30.10 73 156 7.8E-13 T 28-03-2018 MKLM6_RS14680 8e9419a7cdc528eee728f8a1a80983f3 310 Gene3D G3DSA:3.10.520.10 5 297 3.6E-47 T 28-03-2018 MKLM6_RS14680 8e9419a7cdc528eee728f8a1a80983f3 310 SUPERFAMILY SSF143631 4 286 2.59E-83 T 28-03-2018 IPR003374 ApbE-like domain MKLM6_RS14680 8e9419a7cdc528eee728f8a1a80983f3 310 PIRSF PIRSF006268 1 283 5.1E-66 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 MKLM6_RS14680 8e9419a7cdc528eee728f8a1a80983f3 310 Pfam PF02424 ApbE family 11 278 2.9E-71 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 MKLM6_RS09870 a3cf53301252d52bead37b1a52519690 1112 TIGRFAM TIGR02562 cas3_yersinia: CRISPR-associated helicase Cas3, subtype I-F/YPEST 1 1108 4.0E-291 T 28-03-2018 IPR013395 Helicase Cas3, CRISPR-associated, Yersinia-type MKLM6_RS09870 a3cf53301252d52bead37b1a52519690 1112 SUPERFAMILY SSF52540 834 878 4.62E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS09870 a3cf53301252d52bead37b1a52519690 1112 SUPERFAMILY SSF52540 778 799 4.62E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS09870 a3cf53301252d52bead37b1a52519690 1112 SUPERFAMILY SSF52540 531 624 4.62E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS09870 a3cf53301252d52bead37b1a52519690 1112 SUPERFAMILY SSF52540 417 466 4.62E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS09870 a3cf53301252d52bead37b1a52519690 1112 Gene3D G3DSA:3.40.50.300 668 901 0.0016 T 28-03-2018 MKLM6_RS09870 a3cf53301252d52bead37b1a52519690 1112 Gene3D G3DSA:3.40.50.300 234 636 2.5E-10 T 28-03-2018 MKLM6_RS13555 fcf056b3719d4b073ec4875fea206b1a 305 SUPERFAMILY SSF55120 10 235 1.18E-75 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS13555 fcf056b3719d4b073ec4875fea206b1a 305 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 32 182 1.0E-56 T 28-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 MKLM6_RS13555 fcf056b3719d4b073ec4875fea206b1a 305 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 10 298 18.795 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS13555 fcf056b3719d4b073ec4875fea206b1a 305 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 244 298 3.0E-15 T 28-03-2018 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS13555 fcf056b3719d4b073ec4875fea206b1a 305 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 11 221 2.1E-80 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS13555 fcf056b3719d4b073ec4875fea206b1a 305 Gene3D G3DSA:2.30.130.10 242 302 2.7E-18 T 28-03-2018 IPR002478 PUA domain GO:0003723 MKLM6_RS13555 fcf056b3719d4b073ec4875fea206b1a 305 Gene3D G3DSA:3.30.2350.10 9 234 2.4E-78 T 28-03-2018 MKLM6_RS13555 fcf056b3719d4b073ec4875fea206b1a 305 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 183 240 3.9E-13 T 28-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 MKLM6_RS13555 fcf056b3719d4b073ec4875fea206b1a 305 SUPERFAMILY SSF88697 243 299 2.83E-8 T 28-03-2018 IPR015947 PUA-like domain MKLM6_RS13715 5b8b73027cc4e9ff63a9c09e1cdd2d66 76 PRINTS PR00974 Ribosomal protein S18 family signature 39 46 7.0E-19 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS13715 5b8b73027cc4e9ff63a9c09e1cdd2d66 76 PRINTS PR00974 Ribosomal protein S18 family signature 29 39 7.0E-19 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS13715 5b8b73027cc4e9ff63a9c09e1cdd2d66 76 PRINTS PR00974 Ribosomal protein S18 family signature 61 71 7.0E-19 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS13715 5b8b73027cc4e9ff63a9c09e1cdd2d66 76 PRINTS PR00974 Ribosomal protein S18 family signature 47 61 7.0E-19 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS13715 5b8b73027cc4e9ff63a9c09e1cdd2d66 76 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 74 20.908 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS13715 5b8b73027cc4e9ff63a9c09e1cdd2d66 76 Gene3D G3DSA:4.10.640.10 1 76 1.3E-29 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS13715 5b8b73027cc4e9ff63a9c09e1cdd2d66 76 TIGRFAM TIGR00165 S18: ribosomal protein bS18 6 73 3.7E-31 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS13715 5b8b73027cc4e9ff63a9c09e1cdd2d66 76 ProSitePatterns PS00057 Ribosomal protein S18 signature. 22 45 - T 28-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS13715 5b8b73027cc4e9ff63a9c09e1cdd2d66 76 SUPERFAMILY SSF46911 3 75 2.09E-27 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS13715 5b8b73027cc4e9ff63a9c09e1cdd2d66 76 Pfam PF01084 Ribosomal protein S18 20 69 2.6E-25 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS13715 5b8b73027cc4e9ff63a9c09e1cdd2d66 76 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 22 73 8.0E-19 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS05980 4cbfc54db16be650218a840c9dfef451 316 SUPERFAMILY SSF53448 2 222 1.41E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS05980 4cbfc54db16be650218a840c9dfef451 316 Pfam PF00535 Glycosyl transferase family 2 7 169 9.2E-13 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MKLM6_RS05980 4cbfc54db16be650218a840c9dfef451 316 Gene3D G3DSA:3.90.550.10 2 260 8.4E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS12080 a32f7684865bbd9179ed18e96a87b854 212 Pfam PF01292 Prokaryotic cytochrome b561 9 202 3.2E-26 T 28-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 MKLM6_RS12080 a32f7684865bbd9179ed18e96a87b854 212 SUPERFAMILY SSF81342 4 128 1.26E-38 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MKLM6_RS12080 a32f7684865bbd9179ed18e96a87b854 212 SUPERFAMILY SSF81342 155 205 1.26E-38 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MKLM6_RS12080 a32f7684865bbd9179ed18e96a87b854 212 Gene3D G3DSA:1.20.950.20 1 209 1.1E-35 T 28-03-2018 MKLM6_RS04085 948d542bcefd38a0a0574a1fb7217f2b 105 Pfam PF14086 Domain of unknown function (DUF4266) 55 104 2.4E-18 T 28-03-2018 IPR025362 Domain of unknown function DUF4266 MKLM6_RS03915 a99d79bd7b0abef049cf0fdbd2882a5f 214 TIGRFAM TIGR04349 rSAM_QueE_gams: putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 5 214 8.0E-108 T 28-03-2018 IPR027621 Putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE MKLM6_RS03915 a99d79bd7b0abef049cf0fdbd2882a5f 214 Gene3D G3DSA:3.20.20.70 23 203 6.0E-15 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS03915 a99d79bd7b0abef049cf0fdbd2882a5f 214 SUPERFAMILY SSF102114 28 105 8.89E-13 T 28-03-2018 MKLM6_RS03915 a99d79bd7b0abef049cf0fdbd2882a5f 214 Pfam PF04055 Radical SAM superfamily 28 105 2.2E-14 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS03915 a99d79bd7b0abef049cf0fdbd2882a5f 214 Pfam PF13394 4Fe-4S single cluster domain 26 107 1.5E-9 T 28-03-2018 MKLM6_RS03915 a99d79bd7b0abef049cf0fdbd2882a5f 214 PIRSF PIRSF000370 3 214 7.4E-67 T 28-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 MKLM6_RS03915 a99d79bd7b0abef049cf0fdbd2882a5f 214 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 5 211 35.422 T 28-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 SUPERFAMILY SSF56784 310 330 2.23E-55 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 SUPERFAMILY SSF56784 438 668 2.23E-55 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 Pfam PF00689 Cation transporting ATPase, C-terminus 669 841 4.3E-23 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 557 573 2.5E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 755 776 2.5E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 585 601 2.5E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 617 642 2.5E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 441 459 2.5E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 585 604 5.3E-38 T 28-03-2018 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 485 496 5.3E-38 T 28-03-2018 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 142 156 5.3E-38 T 28-03-2018 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 507 517 5.3E-38 T 28-03-2018 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 312 326 5.3E-38 T 28-03-2018 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 609 621 5.3E-38 T 28-03-2018 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 Gene3D G3DSA:2.70.150.10 2 213 2.2E-32 T 28-03-2018 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 554 674 1.6E-31 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 SUPERFAMILY SSF81665 213 306 9.81E-80 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 SUPERFAMILY SSF81665 3 95 9.81E-80 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 SUPERFAMILY SSF81665 635 844 9.81E-80 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 SUPERFAMILY SSF81653 94 208 6.93E-23 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 SMART SM00831 3 57 0.0061 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 314 320 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 Pfam PF00702 haloacid dehalogenase-like hydrolase 310 598 1.4E-27 T 28-03-2018 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 Pfam PF00690 Cation transporter/ATPase, N-terminus 3 51 1.4E-7 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 Gene3D G3DSA:1.20.1110.10 497 843 2.3E-68 T 28-03-2018 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 Gene3D G3DSA:3.40.1110.10 266 492 8.8E-24 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MKLM6_RS09600 24fd0e2124c91b382ab540e1c4aae0c8 853 Pfam PF00122 E1-E2 ATPase 92 291 2.7E-39 T 28-03-2018 MKLM6_RS06840 e94a262386590aca03e506d9660040d8 318 Pfam PF00698 Acyl transferase domain 12 286 1.5E-37 T 28-03-2018 IPR014043 Acyl transferase MKLM6_RS06840 e94a262386590aca03e506d9660040d8 318 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 10 297 1.7E-106 T 28-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 MKLM6_RS06840 e94a262386590aca03e506d9660040d8 318 SUPERFAMILY SSF55048 135 203 2.49E-17 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 MKLM6_RS06840 e94a262386590aca03e506d9660040d8 318 Gene3D G3DSA:3.40.366.10 194 318 3.9E-26 T 28-03-2018 MKLM6_RS06840 e94a262386590aca03e506d9660040d8 318 PIRSF PIRSF000446 8 317 4.5E-108 T 28-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 MKLM6_RS06840 e94a262386590aca03e506d9660040d8 318 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 13 318 7.5E-29 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain MKLM6_RS06840 e94a262386590aca03e506d9660040d8 318 Gene3D G3DSA:3.40.366.10 9 146 9.9E-41 T 28-03-2018 MKLM6_RS06840 e94a262386590aca03e506d9660040d8 318 SUPERFAMILY SSF52151 196 315 5.49E-76 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MKLM6_RS06840 e94a262386590aca03e506d9660040d8 318 SUPERFAMILY SSF52151 10 128 5.49E-76 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MKLM6_RS06840 e94a262386590aca03e506d9660040d8 318 Gene3D G3DSA:3.30.70.250 147 193 1.0E-20 T 28-03-2018 MKLM6_RS05500 d7df858ca9f550ae6162b7f02b9d762f 231 Pfam PF00106 short chain dehydrogenase 2 191 3.3E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS05500 d7df858ca9f550ae6162b7f02b9d762f 231 Gene3D G3DSA:3.40.50.720 1 231 1.7E-53 T 28-03-2018 MKLM6_RS05500 d7df858ca9f550ae6162b7f02b9d762f 231 SUPERFAMILY SSF51735 1 231 1.84E-78 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS05500 d7df858ca9f550ae6162b7f02b9d762f 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 5.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS05500 d7df858ca9f550ae6162b7f02b9d762f 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 5.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS05500 d7df858ca9f550ae6162b7f02b9d762f 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 5.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS05500 d7df858ca9f550ae6162b7f02b9d762f 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.8E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS05500 d7df858ca9f550ae6162b7f02b9d762f 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.8E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS05500 d7df858ca9f550ae6162b7f02b9d762f 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.8E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS05500 d7df858ca9f550ae6162b7f02b9d762f 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.8E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS05500 d7df858ca9f550ae6162b7f02b9d762f 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.8E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS03705 d2910816ce5767f04e5fa495bca5a9c3 984 Gene3D G3DSA:3.10.350.10 190 261 2.4E-7 T 28-03-2018 MKLM6_RS03705 d2910816ce5767f04e5fa495bca5a9c3 984 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 197 251 3.5E-19 T 28-03-2018 IPR020012 Motility protein FimV, N-terminal MKLM6_RS03705 d2910816ce5767f04e5fa495bca5a9c3 984 TIGRFAM TIGR03504 FimV_Cterm: FimV C-terminal domain 940 983 2.6E-15 T 28-03-2018 IPR020011 Motility protein FimV, C-terminal MKLM6_RS03705 d2910816ce5767f04e5fa495bca5a9c3 984 Gene3D G3DSA:1.25.40.10 536 984 2.0E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS07550 35ec0e4b3274c7c6522270f49e0d06ca 441 SMART SM00388 220 285 1.3E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS07550 35ec0e4b3274c7c6522270f49e0d06ca 441 Gene3D G3DSA:1.20.5.1040 119 167 1.1E-8 T 28-03-2018 MKLM6_RS07550 35ec0e4b3274c7c6522270f49e0d06ca 441 Gene3D G3DSA:1.20.5.1040 3 53 1.6E-7 T 28-03-2018 MKLM6_RS07550 35ec0e4b3274c7c6522270f49e0d06ca 441 SUPERFAMILY SSF47384 203 283 6.87E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS07550 35ec0e4b3274c7c6522270f49e0d06ca 441 SUPERFAMILY SSF55874 275 437 4.85E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS07550 35ec0e4b3274c7c6522270f49e0d06ca 441 Gene3D G3DSA:1.10.287.130 210 281 5.0E-15 T 28-03-2018 MKLM6_RS07550 35ec0e4b3274c7c6522270f49e0d06ca 441 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 395 4.8E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS07550 35ec0e4b3274c7c6522270f49e0d06ca 441 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 381 4.8E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS07550 35ec0e4b3274c7c6522270f49e0d06ca 441 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 417 4.8E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS07550 35ec0e4b3274c7c6522270f49e0d06ca 441 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 331 438 1.1E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS07550 35ec0e4b3274c7c6522270f49e0d06ca 441 Pfam PF00512 His Kinase A (phospho-acceptor) domain 221 284 2.2E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS07550 35ec0e4b3274c7c6522270f49e0d06ca 441 Pfam PF08521 Two-component sensor kinase N-terminal 19 143 2.0E-8 T 28-03-2018 IPR013727 Two-component sensor kinase, N-terminal MKLM6_RS07550 35ec0e4b3274c7c6522270f49e0d06ca 441 Gene3D G3DSA:3.30.565.10 291 441 1.5E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS07550 35ec0e4b3274c7c6522270f49e0d06ca 441 SMART SM00387 330 440 1.8E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS18045 72a70667d49ee090654b9ee762522b9a 335 PIRSF PIRSF001359 1 320 2.1E-84 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MKLM6_RS18045 72a70667d49ee090654b9ee762522b9a 335 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 318 5.1E-92 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MKLM6_RS18045 72a70667d49ee090654b9ee762522b9a 335 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 319 1.1E-93 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MKLM6_RS18045 72a70667d49ee090654b9ee762522b9a 335 TIGRFAM TIGR01521 FruBisAldo_II_B: fructose-bisphosphate aldolase, class II, Calvin cycle subtype 4 335 1.3E-161 T 28-03-2018 IPR006412 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 MKLM6_RS18045 72a70667d49ee090654b9ee762522b9a 335 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 85 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MKLM6_RS18045 72a70667d49ee090654b9ee762522b9a 335 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 139 150 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MKLM6_RS18045 72a70667d49ee090654b9ee762522b9a 335 SUPERFAMILY SSF51569 3 320 7.33E-98 T 28-03-2018 MKLM6_RS18045 72a70667d49ee090654b9ee762522b9a 335 Gene3D G3DSA:3.20.20.70 1 322 2.3E-99 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS02740 0a7df7a015c943ec1cce2fb4a4fee920 375 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 10 32 4.5E-34 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MKLM6_RS02740 0a7df7a015c943ec1cce2fb4a4fee920 375 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 208 226 4.5E-34 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MKLM6_RS02740 0a7df7a015c943ec1cce2fb4a4fee920 375 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 228 245 4.5E-34 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MKLM6_RS02740 0a7df7a015c943ec1cce2fb4a4fee920 375 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 272 287 4.5E-34 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MKLM6_RS02740 0a7df7a015c943ec1cce2fb4a4fee920 375 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 302 323 4.5E-34 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MKLM6_RS02740 0a7df7a015c943ec1cce2fb4a4fee920 375 Pfam PF01312 FlhB HrpN YscU SpaS Family 7 347 3.1E-117 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MKLM6_RS02740 0a7df7a015c943ec1cce2fb4a4fee920 375 SUPERFAMILY SSF160544 244 351 1.31E-37 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal MKLM6_RS02740 0a7df7a015c943ec1cce2fb4a4fee920 375 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 7 352 9.1E-118 T 28-03-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 MKLM6_RS02740 0a7df7a015c943ec1cce2fb4a4fee920 375 Gene3D G3DSA:3.40.1690.10 218 353 4.5E-53 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal MKLM6_RS16275 de2b8a7e76f0da3c1072e37f52e832c9 133 SUPERFAMILY SSF46689 48 113 3.23E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS16275 de2b8a7e76f0da3c1072e37f52e832c9 133 Pfam PF08765 Mor transcription activator family 50 113 2.8E-9 T 28-03-2018 IPR014875 Mor transcription activator MKLM6_RS16275 de2b8a7e76f0da3c1072e37f52e832c9 133 Gene3D G3DSA:1.10.10.60 69 122 5.1E-10 T 28-03-2018 MKLM6_RS04645 11b8feba207724ab35f677971e4fde15 284 Gene3D G3DSA:3.60.40.10 29 269 1.7E-45 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS04645 11b8feba207724ab35f677971e4fde15 284 SMART SM00332 22 267 3.6E-28 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS04645 11b8feba207724ab35f677971e4fde15 284 SMART SM00331 35 269 2.6E-23 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS04645 11b8feba207724ab35f677971e4fde15 284 SUPERFAMILY SSF81606 30 269 7.46E-63 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS04645 11b8feba207724ab35f677971e4fde15 284 Pfam PF13672 Protein phosphatase 2C 41 228 1.1E-14 T 28-03-2018 MKLM6_RS19300 61dfcc55a826d7cc3c4ebe4aa3bcb31a 97 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 3 85 1.2E-9 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MKLM6_RS08765 21e020e8ee1093b5ee557ceb0e29886e 187 SUPERFAMILY SSF64288 21 184 2.0E-37 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain MKLM6_RS08765 21e020e8ee1093b5ee557ceb0e29886e 187 Pfam PF04345 Chorismate lyase 25 186 4.4E-29 T 28-03-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745 MKLM6_RS08765 21e020e8ee1093b5ee557ceb0e29886e 187 Gene3D G3DSA:3.40.1410.10 12 185 2.3E-41 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain MKLM6_RS08765 21e020e8ee1093b5ee557ceb0e29886e 187 Hamap MF_01632 Chorismate pyruvate-lyase [ubiC]. 12 186 24.216 T 28-03-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745 MKLM6_RS07135 a01f13881501a6eb4c4d169ee596a9e0 114 Pfam PF02699 Preprotein translocase subunit 25 98 6.6E-26 T 28-03-2018 IPR003849 Preprotein translocase YajC MKLM6_RS07135 a01f13881501a6eb4c4d169ee596a9e0 114 PRINTS PR01853 Bacterial YajC preprotein translocase signature 21 41 9.9E-10 T 28-03-2018 IPR003849 Preprotein translocase YajC MKLM6_RS07135 a01f13881501a6eb4c4d169ee596a9e0 114 PRINTS PR01853 Bacterial YajC preprotein translocase signature 59 77 9.9E-10 T 28-03-2018 IPR003849 Preprotein translocase YajC MKLM6_RS07135 a01f13881501a6eb4c4d169ee596a9e0 114 SMART SM01323 19 101 3.4E-34 T 28-03-2018 IPR003849 Preprotein translocase YajC MKLM6_RS07135 a01f13881501a6eb4c4d169ee596a9e0 114 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 25 101 4.5E-24 T 28-03-2018 IPR003849 Preprotein translocase YajC MKLM6_RS18145 aedb9cef9f2390e3b2b223f6a03272ff 694 Gene3D G3DSA:3.30.450.20 233 382 4.1E-23 T 28-03-2018 MKLM6_RS18145 aedb9cef9f2390e3b2b223f6a03272ff 694 Gene3D G3DSA:3.30.450.20 383 526 1.3E-38 T 28-03-2018 MKLM6_RS18145 aedb9cef9f2390e3b2b223f6a03272ff 694 Gene3D G3DSA:3.30.70.270 527 692 1.1E-58 T 28-03-2018 MKLM6_RS18145 aedb9cef9f2390e3b2b223f6a03272ff 694 SUPERFAMILY SSF55785 405 520 2.54E-27 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18145 aedb9cef9f2390e3b2b223f6a03272ff 694 Pfam PF00990 Diguanylate cyclase, GGDEF domain 529 687 6.2E-44 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS18145 aedb9cef9f2390e3b2b223f6a03272ff 694 SMART SM00091 271 338 2.3E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18145 aedb9cef9f2390e3b2b223f6a03272ff 694 SMART SM00091 400 468 1.2E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18145 aedb9cef9f2390e3b2b223f6a03272ff 694 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 47 159 8.0E-16 T 28-03-2018 IPR029095 NarX-like, N-terminal MKLM6_RS18145 aedb9cef9f2390e3b2b223f6a03272ff 694 SMART SM00267 518 691 1.0E-60 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS18145 aedb9cef9f2390e3b2b223f6a03272ff 694 Pfam PF13426 PAS domain 282 387 6.4E-13 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18145 aedb9cef9f2390e3b2b223f6a03272ff 694 SMART SM00086 348 388 1.1 T 28-03-2018 IPR001610 PAC motif MKLM6_RS18145 aedb9cef9f2390e3b2b223f6a03272ff 694 SMART SM00086 475 518 5.9E-12 T 28-03-2018 IPR001610 PAC motif MKLM6_RS18145 aedb9cef9f2390e3b2b223f6a03272ff 694 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 267 393 7.5E-23 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18145 aedb9cef9f2390e3b2b223f6a03272ff 694 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 397 525 3.1E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18145 aedb9cef9f2390e3b2b223f6a03272ff 694 SUPERFAMILY SSF55785 282 397 2.09E-23 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18145 aedb9cef9f2390e3b2b223f6a03272ff 694 Pfam PF08447 PAS fold 426 512 3.7E-26 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS18145 aedb9cef9f2390e3b2b223f6a03272ff 694 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 525 691 5.6E-52 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS18145 aedb9cef9f2390e3b2b223f6a03272ff 694 SUPERFAMILY SSF55073 534 690 1.73E-48 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS22060 cdb560d1e34f22959f42d85417371cb9 313 Pfam PF07728 AAA domain (dynein-related subfamily) 61 200 3.8E-22 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 MKLM6_RS22060 cdb560d1e34f22959f42d85417371cb9 313 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 214 306 6.3E-16 T 28-03-2018 IPR013615 CbbQ/NirQ/NorQ, C-terminal MKLM6_RS22060 cdb560d1e34f22959f42d85417371cb9 313 Gene3D G3DSA:3.40.50.300 48 238 7.5E-21 T 28-03-2018 MKLM6_RS22060 cdb560d1e34f22959f42d85417371cb9 313 SUPERFAMILY SSF52540 38 275 3.56E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS07640 49085ef1bb66aab39853fe711345c2cb 269 PRINTS PR01543 Arylamine N-acetyltransferase signature 44 67 4.4E-8 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 MKLM6_RS07640 49085ef1bb66aab39853fe711345c2cb 269 PRINTS PR01543 Arylamine N-acetyltransferase signature 99 124 4.4E-8 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 MKLM6_RS07640 49085ef1bb66aab39853fe711345c2cb 269 PRINTS PR01543 Arylamine N-acetyltransferase signature 20 43 4.4E-8 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 MKLM6_RS07640 49085ef1bb66aab39853fe711345c2cb 269 Pfam PF00797 N-acetyltransferase 20 254 4.5E-63 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 MKLM6_RS07640 49085ef1bb66aab39853fe711345c2cb 269 Gene3D G3DSA:3.30.2140.10 159 267 8.1E-11 T 28-03-2018 MKLM6_RS07640 49085ef1bb66aab39853fe711345c2cb 269 Gene3D G3DSA:3.30.2140.10 2 158 4.2E-38 T 28-03-2018 MKLM6_RS07640 49085ef1bb66aab39853fe711345c2cb 269 SUPERFAMILY SSF54001 2 263 2.45E-71 T 28-03-2018 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 PRINTS PR00418 DNA topoisomerase II family signature 267 280 2.4E-71 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 PRINTS PR00418 DNA topoisomerase II family signature 419 433 2.4E-71 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 PRINTS PR00418 DNA topoisomerase II family signature 35 50 2.4E-71 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 PRINTS PR00418 DNA topoisomerase II family signature 504 521 2.4E-71 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 PRINTS PR00418 DNA topoisomerase II family signature 70 83 2.4E-71 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 PRINTS PR00418 DNA topoisomerase II family signature 113 127 2.4E-71 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 PRINTS PR00418 DNA topoisomerase II family signature 524 536 2.4E-71 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 PRINTS PR00418 DNA topoisomerase II family signature 733 749 2.4E-71 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 PRINTS PR00418 DNA topoisomerase II family signature 486 502 2.4E-71 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 SUPERFAMILY SSF55874 4 217 1.35E-72 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 Gene3D G3DSA:3.30.230.10 220 391 1.5E-66 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 5 801 0.0 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 172 2.5E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 Pfam PF00204 DNA gyrase B 220 389 6.7E-62 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 2 801 102.94 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 Gene3D G3DSA:3.30.565.10 17 219 3.6E-73 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 SUPERFAMILY SSF56719 393 559 8.11E-87 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 SUPERFAMILY SSF56719 727 793 8.11E-87 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 SMART SM00387 31 175 2.0E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 Pfam PF01751 Toprim domain 418 530 6.3E-19 T 28-03-2018 IPR006171 TOPRIM domain MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 PRINTS PR01159 DNA gyrase subunit B signature 311 327 8.1E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 PRINTS PR01159 DNA gyrase subunit B signature 754 766 8.1E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 PRINTS PR01159 DNA gyrase subunit B signature 195 208 8.1E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 PRINTS PR01159 DNA gyrase subunit B signature 770 786 8.1E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 PRINTS PR01159 DNA gyrase subunit B signature 5 15 8.1E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 PRINTS PR01159 DNA gyrase subunit B signature 373 393 8.1E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 PRINTS PR01159 DNA gyrase subunit B signature 180 195 8.1E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 PRINTS PR01159 DNA gyrase subunit B signature 359 373 8.1E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 PRINTS PR01159 DNA gyrase subunit B signature 469 478 8.1E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 PRINTS PR01159 DNA gyrase subunit B signature 219 241 8.1E-75 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 ProSitePatterns PS00177 DNA topoisomerase II signature. 421 429 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 SMART SM00433 35 794 4.2E-269 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 SUPERFAMILY SSF54211 220 391 4.55E-62 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 Gene3D G3DSA:3.40.50.670 400 798 1.8E-106 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS21800 673c5fc839d28dad58a77b563b75f274 801 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 729 789 1.5E-27 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 MKLM6_RS04950 fc736b5fa80a909d2b5a3637df885933 465 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 19 434 1.0E-110 T 28-03-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 MKLM6_RS04950 fc736b5fa80a909d2b5a3637df885933 465 SUPERFAMILY SSF53807 6 440 1.24E-121 T 28-03-2018 MKLM6_RS04950 fc736b5fa80a909d2b5a3637df885933 465 Gene3D G3DSA:3.40.50.1980 19 165 3.1E-36 T 28-03-2018 MKLM6_RS04950 fc736b5fa80a909d2b5a3637df885933 465 Gene3D G3DSA:3.40.50.1980 170 280 6.0E-33 T 28-03-2018 MKLM6_RS04950 fc736b5fa80a909d2b5a3637df885933 465 TIGRFAM TIGR01285 nifN: nitrogenase molybdenum-iron cofactor biosynthesis protein NifN 2 434 2.5E-178 T 28-03-2018 IPR005975 Nitrogenase molybdenum-iron cofactor biosynthesis protein GO:0006461|GO:0009399 MKLM6_RS04950 fc736b5fa80a909d2b5a3637df885933 465 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 37 44 - T 28-03-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 MKLM6_RS04950 fc736b5fa80a909d2b5a3637df885933 465 Gene3D G3DSA:3.40.50.1980 351 448 2.1E-17 T 28-03-2018 MKLM6_RS04950 fc736b5fa80a909d2b5a3637df885933 465 Gene3D G3DSA:1.20.89.10 281 350 2.9E-24 T 28-03-2018 MKLM6_RS21670 ab25e2bca1e0202c4104544a65ec713a 563 Pfam PF00795 Carbon-nitrogen hydrolase 8 247 1.3E-23 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS21670 ab25e2bca1e0202c4104544a65ec713a 563 Gene3D G3DSA:3.60.110.10 1 258 4.1E-55 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS21670 ab25e2bca1e0202c4104544a65ec713a 563 TIGRFAM TIGR00552 nadE: NAD+ synthetase 286 542 3.3E-56 T 28-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 MKLM6_RS21670 ab25e2bca1e0202c4104544a65ec713a 563 SUPERFAMILY SSF52402 268 547 3.45E-70 T 28-03-2018 MKLM6_RS21670 ab25e2bca1e0202c4104544a65ec713a 563 Pfam PF02540 NAD synthase 279 540 3.7E-64 T 28-03-2018 IPR022310 NAD/GMP synthase MKLM6_RS21670 ab25e2bca1e0202c4104544a65ec713a 563 PIRSF PIRSF006630 260 563 4.5E-94 T 28-03-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MKLM6_RS21670 ab25e2bca1e0202c4104544a65ec713a 563 PIRSF PIRSF006630 4 262 2.1E-67 T 28-03-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MKLM6_RS21670 ab25e2bca1e0202c4104544a65ec713a 563 Gene3D G3DSA:3.40.50.620 277 563 4.5E-64 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS21670 ab25e2bca1e0202c4104544a65ec713a 563 SUPERFAMILY SSF56317 5 249 1.7E-54 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS21785 1c0cf30e11b09d9e2e81f78005358fbe 246 Gene3D G3DSA:3.30.420.40 116 246 3.7E-22 T 28-03-2018 MKLM6_RS21785 1c0cf30e11b09d9e2e81f78005358fbe 246 Pfam PF00480 ROK family 4 157 2.6E-18 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 MKLM6_RS21785 1c0cf30e11b09d9e2e81f78005358fbe 246 SUPERFAMILY SSF53067 1 243 1.04E-31 T 28-03-2018 MKLM6_RS21785 1c0cf30e11b09d9e2e81f78005358fbe 246 Gene3D G3DSA:3.30.420.40 1 115 3.1E-20 T 28-03-2018 MKLM6_RS04900 f405e079cc3ebe1c605350bad87a63ca 786 Pfam PF00990 Diguanylate cyclase, GGDEF domain 365 522 5.2E-41 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS04900 f405e079cc3ebe1c605350bad87a63ca 786 SMART SM00304 180 233 4.1E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS04900 f405e079cc3ebe1c605350bad87a63ca 786 SMART SM00267 354 526 1.1E-56 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS04900 f405e079cc3ebe1c605350bad87a63ca 786 Pfam PF00672 HAMP domain 181 229 3.3E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS04900 f405e079cc3ebe1c605350bad87a63ca 786 SMART SM00091 240 306 1.8E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS04900 f405e079cc3ebe1c605350bad87a63ca 786 Gene3D G3DSA:3.30.70.270 370 528 7.1E-55 T 28-03-2018 MKLM6_RS04900 f405e079cc3ebe1c605350bad87a63ca 786 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 363 525 8.3E-44 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS04900 f405e079cc3ebe1c605350bad87a63ca 786 Pfam PF13426 PAS domain 253 353 5.1E-11 T 28-03-2018 IPR000014 PAS domain MKLM6_RS04900 f405e079cc3ebe1c605350bad87a63ca 786 SUPERFAMILY SSF55073 370 528 3.69E-47 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS04900 f405e079cc3ebe1c605350bad87a63ca 786 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 241 360 1.2E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS04900 f405e079cc3ebe1c605350bad87a63ca 786 Gene3D G3DSA:3.30.450.20 239 369 8.6E-23 T 28-03-2018 MKLM6_RS04900 f405e079cc3ebe1c605350bad87a63ca 786 SMART SM00052 538 785 8.3E-72 T 28-03-2018 IPR001633 EAL domain MKLM6_RS04900 f405e079cc3ebe1c605350bad87a63ca 786 SMART SM00086 313 354 2.9E-4 T 28-03-2018 IPR001610 PAC motif MKLM6_RS04900 f405e079cc3ebe1c605350bad87a63ca 786 SUPERFAMILY SSF55785 233 352 2.79E-21 T 28-03-2018 IPR000014 PAS domain MKLM6_RS04900 f405e079cc3ebe1c605350bad87a63ca 786 Pfam PF00563 EAL domain 545 780 1.6E-60 T 28-03-2018 IPR001633 EAL domain MKLM6_RS04900 f405e079cc3ebe1c605350bad87a63ca 786 SUPERFAMILY SSF158472 181 229 7.06E-7 T 28-03-2018 MKLM6_RS04900 f405e079cc3ebe1c605350bad87a63ca 786 Pfam PF17152 Periplasmic sensor domain 42 142 4.2E-18 T 28-03-2018 IPR033417 Periplasmic sensor domain CHASE8 MKLM6_RS04900 f405e079cc3ebe1c605350bad87a63ca 786 Gene3D G3DSA:3.20.20.450 529 786 8.5E-74 T 28-03-2018 IPR001633 EAL domain MKLM6_RS04900 f405e079cc3ebe1c605350bad87a63ca 786 SUPERFAMILY SSF141868 544 785 2.88E-69 T 28-03-2018 IPR001633 EAL domain MKLM6_RS17625 3b884686435914df254b5c757986ebdd 332 SUPERFAMILY SSF109998 38 171 9.81E-19 T 28-03-2018 IPR027304 Trigger factor/SurA domain MKLM6_RS17625 3b884686435914df254b5c757986ebdd 332 Pfam PF13616 PPIC-type PPIASE domain 142 229 2.2E-20 T 28-03-2018 MKLM6_RS17625 3b884686435914df254b5c757986ebdd 332 Gene3D G3DSA:3.10.50.40 134 258 3.9E-36 T 28-03-2018 MKLM6_RS17625 3b884686435914df254b5c757986ebdd 332 SUPERFAMILY SSF54534 144 233 1.11E-29 T 28-03-2018 MKLM6_RS09500 b0c6700156fd53dc4b80ccca9c3243bf 791 SUPERFAMILY SSF55681 467 686 2.73E-51 T 28-03-2018 MKLM6_RS09500 b0c6700156fd53dc4b80ccca9c3243bf 791 SMART SM00874 403 471 3.4E-24 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MKLM6_RS09500 b0c6700156fd53dc4b80ccca9c3243bf 791 SUPERFAMILY SSF50249 35 196 4.86E-49 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS09500 b0c6700156fd53dc4b80ccca9c3243bf 791 Gene3D G3DSA:3.30.70.380 693 790 2.0E-24 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MKLM6_RS09500 b0c6700156fd53dc4b80ccca9c3243bf 791 SMART SM00896 697 790 1.6E-38 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MKLM6_RS09500 b0c6700156fd53dc4b80ccca9c3243bf 791 SUPERFAMILY SSF46955 405 475 2.11E-17 T 28-03-2018 IPR009061 Putative DNA-binding domain MKLM6_RS09500 b0c6700156fd53dc4b80ccca9c3243bf 791 Gene3D G3DSA:3.30.930.10 492 686 5.8E-37 T 28-03-2018 MKLM6_RS09500 b0c6700156fd53dc4b80ccca9c3243bf 791 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 784 44.113 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MKLM6_RS09500 b0c6700156fd53dc4b80ccca9c3243bf 791 Pfam PF03483 B3/4 domain 212 385 7.3E-67 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 MKLM6_RS09500 b0c6700156fd53dc4b80ccca9c3243bf 791 Gene3D G3DSA:3.30.56.10 402 475 1.4E-22 T 28-03-2018 MKLM6_RS09500 b0c6700156fd53dc4b80ccca9c3243bf 791 SMART SM00873 212 385 1.9E-91 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 MKLM6_RS09500 b0c6700156fd53dc4b80ccca9c3243bf 791 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 790 7.1E-261 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MKLM6_RS09500 b0c6700156fd53dc4b80ccca9c3243bf 791 Pfam PF01588 Putative tRNA binding domain 45 145 2.3E-25 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 MKLM6_RS09500 b0c6700156fd53dc4b80ccca9c3243bf 791 Pfam PF03484 tRNA synthetase B5 domain 406 471 3.3E-17 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MKLM6_RS09500 b0c6700156fd53dc4b80ccca9c3243bf 791 SUPERFAMILY SSF56037 199 396 1.86E-72 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 MKLM6_RS09500 b0c6700156fd53dc4b80ccca9c3243bf 791 Pfam PF03147 Ferredoxin-fold anticodon binding domain 697 790 2.8E-28 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MKLM6_RS09500 b0c6700156fd53dc4b80ccca9c3243bf 791 Gene3D G3DSA:3.50.40.10 195 395 4.9E-69 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 MKLM6_RS09500 b0c6700156fd53dc4b80ccca9c3243bf 791 SUPERFAMILY SSF54991 691 790 2.35E-28 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MKLM6_RS09500 b0c6700156fd53dc4b80ccca9c3243bf 791 Gene3D G3DSA:3.30.56.10 1 189 1.2E-52 T 28-03-2018 MKLM6_RS12180 9a063a79f59d0602f12dfe7674a167e0 573 Pfam PF01930 Domain of unknown function DUF83 30 215 4.1E-24 T 28-03-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 MKLM6_RS12180 9a063a79f59d0602f12dfe7674a167e0 573 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 64 563 26.686 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 MKLM6_RS12180 9a063a79f59d0602f12dfe7674a167e0 573 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 30 215 1.1E-28 T 28-03-2018 IPR013343 CRISPR-associated protein Cas4 MKLM6_RS12180 9a063a79f59d0602f12dfe7674a167e0 573 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 241 567 1.0E-76 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 MKLM6_RS12180 9a063a79f59d0602f12dfe7674a167e0 573 Pfam PF01867 CRISPR associated protein Cas1 241 527 1.2E-94 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 MKLM6_RS08730 1f8d2bfd960964197813302359350235 218 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 213 1.4E-89 T 28-03-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 MKLM6_RS08730 1f8d2bfd960964197813302359350235 218 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS08730 1f8d2bfd960964197813302359350235 218 SUPERFAMILY SSF52540 1 216 1.77E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS08730 1f8d2bfd960964197813302359350235 218 SMART SM00382 27 213 2.5E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS08730 1f8d2bfd960964197813302359350235 218 Pfam PF00005 ABC transporter 18 165 8.7E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS08730 1f8d2bfd960964197813302359350235 218 Gene3D G3DSA:3.40.50.300 1 218 1.5E-62 T 28-03-2018 MKLM6_RS14085 8f320b861ebaa376bef47d275518e768 335 SMART SM00471 161 296 7.8E-11 T 28-03-2018 IPR003607 HD/PDEase domain MKLM6_RS14085 8f320b861ebaa376bef47d275518e768 335 SMART SM00448 6 119 5.5E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14085 8f320b861ebaa376bef47d275518e768 335 Pfam PF00072 Response regulator receiver domain 8 119 7.0E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14085 8f320b861ebaa376bef47d275518e768 335 Pfam PF01966 HD domain 166 287 3.5E-19 T 28-03-2018 IPR006674 HD domain MKLM6_RS14085 8f320b861ebaa376bef47d275518e768 335 Gene3D G3DSA:1.10.3210.10 127 331 1.7E-46 T 28-03-2018 MKLM6_RS14085 8f320b861ebaa376bef47d275518e768 335 Gene3D G3DSA:3.40.50.2300 5 126 4.6E-37 T 28-03-2018 MKLM6_RS14085 8f320b861ebaa376bef47d275518e768 335 TIGRFAM TIGR00277 HDIG: HDIG domain 166 255 5.8E-8 T 28-03-2018 IPR006675 HDIG domain MKLM6_RS14085 8f320b861ebaa376bef47d275518e768 335 SUPERFAMILY SSF52172 6 135 1.57E-41 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS14085 8f320b861ebaa376bef47d275518e768 335 SUPERFAMILY SSF109604 150 326 3.66E-37 T 28-03-2018 MKLM6_RS16910 0911105116479a550d3d6ea19f21dad5 338 PIRSF PIRSF000116 201 333 3.4E-13 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MKLM6_RS16910 0911105116479a550d3d6ea19f21dad5 338 PIRSF PIRSF000116 4 204 2.7E-47 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MKLM6_RS16910 0911105116479a550d3d6ea19f21dad5 338 Gene3D G3DSA:1.10.1040.10 60 330 7.8E-113 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MKLM6_RS16910 0911105116479a550d3d6ea19f21dad5 338 SUPERFAMILY SSF48179 183 332 2.21E-69 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MKLM6_RS16910 0911105116479a550d3d6ea19f21dad5 338 SUPERFAMILY SSF51735 1 182 8.86E-74 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS16910 0911105116479a550d3d6ea19f21dad5 338 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 327 2.5E-130 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MKLM6_RS16910 0911105116479a550d3d6ea19f21dad5 338 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 3.8E-64 T 28-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MKLM6_RS16910 0911105116479a550d3d6ea19f21dad5 338 Gene3D G3DSA:3.40.50.720 6 48 0.014 T 28-03-2018 MKLM6_RS16910 0911105116479a550d3d6ea19f21dad5 338 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 328 44.862 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MKLM6_RS16910 0911105116479a550d3d6ea19f21dad5 338 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 1.8E-73 T 28-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 Gene3D G3DSA:3.40.50.10600 645 758 7.5E-29 T 28-03-2018 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 Gene3D G3DSA:3.40.50.2300 1036 1175 3.9E-41 T 28-03-2018 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 Gene3D G3DSA:1.20.120.620 12 77 6.0E-5 T 28-03-2018 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 SUPERFAMILY SSF47384 782 862 1.02E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 Pfam PF00512 His Kinase A (phospho-acceptor) domain 797 861 2.3E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 Gene3D G3DSA:3.30.450.20 233 359 1.6E-20 T 28-03-2018 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 Pfam PF00072 Response regulator receiver domain 1051 1162 8.9E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 SMART SM00387 907 1023 6.1E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 Gene3D G3DSA:3.30.565.10 856 1023 9.8E-45 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 SUPERFAMILY SSF55785 117 229 8.38E-22 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 SMART SM00091 645 711 9.3E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 SMART SM00091 366 435 0.035 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 SMART SM00091 522 589 2.3E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 SMART SM00091 111 177 1.4E-11 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 Gene3D G3DSA:1.10.287.130 786 855 1.4E-19 T 28-03-2018 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 907 1022 3.6E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 SUPERFAMILY SSF55785 223 352 1.77E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 SUPERFAMILY SSF55785 655 755 1.08E-28 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 Pfam PF01627 Hpt domain 1220 1297 6.1E-8 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 SMART SM00388 796 861 1.5E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 SUPERFAMILY SSF55785 512 635 2.09E-22 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 PRINTS PR00344 Bacterial sensor protein C-terminal signature 948 962 1.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 PRINTS PR00344 Bacterial sensor protein C-terminal signature 983 1001 1.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1007 1020 1.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 PRINTS PR00344 Bacterial sensor protein C-terminal signature 966 976 1.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 Pfam PF13426 PAS domain 655 757 1.3E-17 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 SUPERFAMILY SSF47226 1145 1158 3.01E-16 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 SUPERFAMILY SSF47226 1199 1296 3.01E-16 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 Pfam PF08447 PAS fold 389 471 4.6E-8 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 Pfam PF08447 PAS fold 261 347 3.8E-9 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 Pfam PF08447 PAS fold 134 219 5.5E-13 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 Pfam PF08447 PAS fold 546 631 1.8E-17 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 SMART SM00086 312 354 3.4E-6 T 28-03-2018 IPR001610 PAC motif MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 SMART SM00086 595 637 2.1E-9 T 28-03-2018 IPR001610 PAC motif MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 SMART SM00086 717 758 7.4E-5 T 28-03-2018 IPR001610 PAC motif MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 SMART SM00086 446 482 4.6 T 28-03-2018 IPR001610 PAC motif MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 SMART SM00086 184 226 0.12 T 28-03-2018 IPR001610 PAC motif MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 Gene3D G3DSA:1.20.120.160 1198 1307 1.5E-14 T 28-03-2018 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 115 230 4.5E-23 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 647 764 2.0E-21 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 362 488 1.2E-12 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 518 644 6.0E-12 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 SUPERFAMILY SSF55874 850 1019 3.93E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 SUPERFAMILY SSF55785 351 480 2.44E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 SUPERFAMILY SSF52172 1047 1173 7.83E-39 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 SMART SM00448 1049 1162 9.2E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 Gene3D G3DSA:3.30.450.20 101 232 2.1E-27 T 28-03-2018 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 Gene3D G3DSA:3.30.450.20 360 504 1.9E-29 T 28-03-2018 MKLM6_RS05670 0e3b5e9e9d79db84c6585d310455fddd 1402 Gene3D G3DSA:3.30.450.20 505 644 2.1E-33 T 28-03-2018 MKLM6_RS15780 d49b1f32c1f15f7a04cf7eadeaefd023 408 Pfam PF08421 Putative zinc binding domain 3 64 7.8E-22 T 28-03-2018 IPR013630 Methyltransferase putative zinc binding domain MKLM6_RS15780 d49b1f32c1f15f7a04cf7eadeaefd023 408 Pfam PF13489 Methyltransferase domain 93 237 1.3E-12 T 28-03-2018 MKLM6_RS15780 d49b1f32c1f15f7a04cf7eadeaefd023 408 SUPERFAMILY SSF53335 57 252 1.82E-21 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS15780 d49b1f32c1f15f7a04cf7eadeaefd023 408 Pfam PF08484 C-methyltransferase C-terminal domain 244 403 6.6E-64 T 28-03-2018 IPR013691 C-methyltransferase MKLM6_RS15780 d49b1f32c1f15f7a04cf7eadeaefd023 408 Gene3D G3DSA:3.40.50.150 55 256 3.4E-28 T 28-03-2018 MKLM6_RS21815 22ccf921e1b0124277301e513040b53b 497 Pfam PF08870 DNA sulphur modification protein DndE 2 101 3.1E-6 T 28-03-2018 IPR014969 DNA sulphur modification protein DndE MKLM6_RS21815 22ccf921e1b0124277301e513040b53b 497 SUPERFAMILY SSF52540 145 427 4.04E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS21815 22ccf921e1b0124277301e513040b53b 497 Gene3D G3DSA:3.40.50.300 72 479 1.4E-15 T 28-03-2018 MKLM6_RS21815 22ccf921e1b0124277301e513040b53b 497 Pfam PF10412 Type IV secretion-system coupling protein DNA-binding domain 170 210 3.9E-5 T 28-03-2018 IPR019476 Type IV secretion system coupling protein TraD, DNA-binding domain MKLM6_RS21815 22ccf921e1b0124277301e513040b53b 497 SMART SM00382 166 486 0.0054 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS14080 e46fd0fd9bbe3a303e250d1c46beac9e 591 Pfam PF00072 Response regulator receiver domain 395 504 2.5E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14080 e46fd0fd9bbe3a303e250d1c46beac9e 591 SUPERFAMILY SSF55874 196 365 1.18E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14080 e46fd0fd9bbe3a303e250d1c46beac9e 591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 293 307 2.8E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14080 e46fd0fd9bbe3a303e250d1c46beac9e 591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 311 321 2.8E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14080 e46fd0fd9bbe3a303e250d1c46beac9e 591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 326 344 2.8E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14080 e46fd0fd9bbe3a303e250d1c46beac9e 591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 363 2.8E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14080 e46fd0fd9bbe3a303e250d1c46beac9e 591 SMART SM00387 254 366 1.2E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14080 e46fd0fd9bbe3a303e250d1c46beac9e 591 SUPERFAMILY SSF52172 392 518 1.57E-33 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS14080 e46fd0fd9bbe3a303e250d1c46beac9e 591 SMART SM00388 141 207 3.5E-23 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS14080 e46fd0fd9bbe3a303e250d1c46beac9e 591 Pfam PF00512 His Kinase A (phospho-acceptor) domain 142 207 9.5E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS14080 e46fd0fd9bbe3a303e250d1c46beac9e 591 SMART SM00448 393 506 5.2E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14080 e46fd0fd9bbe3a303e250d1c46beac9e 591 Gene3D G3DSA:3.40.50.2300 385 558 6.1E-36 T 28-03-2018 MKLM6_RS14080 e46fd0fd9bbe3a303e250d1c46beac9e 591 SUPERFAMILY SSF47384 127 208 4.71E-23 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS14080 e46fd0fd9bbe3a303e250d1c46beac9e 591 Gene3D G3DSA:3.30.565.10 202 366 1.5E-49 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14080 e46fd0fd9bbe3a303e250d1c46beac9e 591 Gene3D G3DSA:1.10.287.130 131 201 1.1E-21 T 28-03-2018 MKLM6_RS14080 e46fd0fd9bbe3a303e250d1c46beac9e 591 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 254 365 1.1E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13650 f6bce7e8e8a9b0cd52bc60c2058e8e36 262 ProDom PD587589 PHOSPHODIESTERASE ICC METALLOPHOSPHOESTERASE CYCLIC REGULATOR LACZ AMP HYDROLASE 3'5'-CYCLIC-NUCLEOTIDE EXPRESSION 193 248 1.0E-8 T 28-03-2018 IPR013622 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA, C-terminal KEGG: 00230+3.1.4.53 MKLM6_RS13650 f6bce7e8e8a9b0cd52bc60c2058e8e36 262 Gene3D G3DSA:3.60.21.10 2 254 1.2E-33 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS13650 f6bce7e8e8a9b0cd52bc60c2058e8e36 262 SUPERFAMILY SSF56300 4 257 4.1E-51 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS13650 f6bce7e8e8a9b0cd52bc60c2058e8e36 262 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 4 248 35.657 T 28-03-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 MKLM6_RS13650 f6bce7e8e8a9b0cd52bc60c2058e8e36 262 Pfam PF00149 Calcineurin-like phosphoesterase 4 193 3.1E-12 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 SUPERFAMILY SSF52777 14 191 2.67E-46 T 28-03-2018 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 Gene3D G3DSA:3.40.50.980 1516 1673 6.0E-44 T 28-03-2018 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 Pfam PF00550 Phosphopantetheine attachment site 984 1047 4.1E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 Pfam PF00550 Phosphopantetheine attachment site 2029 2093 1.2E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 SUPERFAMILY SSF52777 1072 1248 3.11E-45 T 28-03-2018 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 Gene3D G3DSA:3.40.50.720 2137 2471 9.4E-34 T 28-03-2018 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 486 893 3.1E-110 T 28-03-2018 IPR010071 Amino acid adenylation domain MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1545 1942 1.6E-133 T 28-03-2018 IPR010071 Amino acid adenylation domain MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 Gene3D G3DSA:3.40.50.980 456 613 1.0E-35 T 28-03-2018 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 SMART SM00823 Phosphopantetheine attachment site 2028 2097 8.6E-6 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 SMART SM00823 Phosphopantetheine attachment site 982 1051 0.0085 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 Pfam PF00668 Condensation domain 9 442 9.2E-87 T 28-03-2018 IPR001242 Condensation domain MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 Pfam PF00668 Condensation domain 1070 1503 9.1E-97 T 28-03-2018 IPR001242 Condensation domain MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1669 1680 - T 28-03-2018 IPR020845 AMP-binding, conserved site MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 SUPERFAMILY SSF47336 2023 2093 9.81E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 Gene3D G3DSA:3.30.559.10 1054 1274 1.5E-42 T 28-03-2018 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 Gene3D G3DSA:3.30.559.10 3 209 2.2E-42 T 28-03-2018 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 SUPERFAMILY SSF52777 1256 1487 3.89E-58 T 28-03-2018 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 SUPERFAMILY SSF51735 2139 2407 5.56E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 SUPERFAMILY SSF56801 424 990 3.53E-135 T 28-03-2018 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 Pfam PF07993 Male sterility protein 2142 2380 1.4E-56 T 28-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 ProSitePatterns PS00455 Putative AMP-binding domain signature. 607 618 - T 28-03-2018 IPR020845 AMP-binding, conserved site MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 2139 2480 7.4E-82 T 28-03-2018 IPR010080 Thioester reductase-like domain MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 Gene3D G3DSA:1.10.1200.10 986 1053 6.9E-22 T 28-03-2018 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 Pfam PF13193 AMP-binding enzyme C-terminal domain 878 954 4.3E-9 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 Pfam PF13193 AMP-binding enzyme C-terminal domain 1926 2001 8.4E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 Gene3D G3DSA:3.40.50.980 614 774 1.9E-31 T 28-03-2018 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 Gene3D G3DSA:3.40.50.980 1674 1825 1.8E-31 T 28-03-2018 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 Gene3D G3DSA:2.30.38.10 1827 1911 4.5E-23 T 28-03-2018 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 SUPERFAMILY SSF47336 975 1082 9.16E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 Gene3D G3DSA:2.30.38.10 778 859 3.9E-20 T 28-03-2018 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 Gene3D G3DSA:3.30.300.30 1913 2033 3.3E-34 T 28-03-2018 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 Gene3D G3DSA:3.30.300.30 866 985 4.2E-36 T 28-03-2018 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 SUPERFAMILY SSF56801 1482 2041 4.71E-151 T 28-03-2018 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 Gene3D G3DSA:1.10.1200.10 2034 2110 2.3E-23 T 28-03-2018 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 Pfam PF00501 AMP-binding enzyme 465 870 5.6E-80 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 Pfam PF00501 AMP-binding enzyme 1525 1918 3.7E-94 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MKLM6_RS12280 6ea3cf53da573c8f8034d57508551a6f 2508 SUPERFAMILY SSF52777 192 429 5.78E-51 T 28-03-2018 MKLM6_RS05385 c40024e8c49f03eafa923d1f400e2405 141 PIRSF PIRSF020565 1 141 1.4E-41 T 28-03-2018 IPR016776 3-hydroxylacyl-(acyl carrier protein) dehydratase, predicted MKLM6_RS05385 c40024e8c49f03eafa923d1f400e2405 141 SUPERFAMILY SSF54637 3 122 5.72E-16 T 28-03-2018 IPR029069 HotDog domain MKLM6_RS05385 c40024e8c49f03eafa923d1f400e2405 141 Gene3D G3DSA:3.10.129.10 1 124 4.3E-16 T 28-03-2018 MKLM6_RS21050 03726d1db5e5bb3753211e347f2a25a2 152 Pfam PF02623 FliW protein 19 134 1.5E-28 T 28-03-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 MKLM6_RS21050 03726d1db5e5bb3753211e347f2a25a2 152 SUPERFAMILY SSF141457 1 134 8.89E-31 T 28-03-2018 IPR024046 Flagellar assembly factor FliW domain MKLM6_RS21050 03726d1db5e5bb3753211e347f2a25a2 152 Hamap MF_01185 Flagellar assembly factor FliW [fliW]. 17 143 19.286 T 28-03-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 MKLM6_RS21050 03726d1db5e5bb3753211e347f2a25a2 152 Gene3D G3DSA:2.30.290.10 1 148 1.6E-38 T 28-03-2018 IPR024046 Flagellar assembly factor FliW domain MKLM6_RS21270 2052a50592c96a3ad3c5bdb29b2b98cc 3456 SMART SM00912 55 164 1.3E-28 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MKLM6_RS21270 2052a50592c96a3ad3c5bdb29b2b98cc 3456 Gene3D G3DSA:2.160.20.10 1345 1688 0.039 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS21270 2052a50592c96a3ad3c5bdb29b2b98cc 3456 Gene3D G3DSA:2.160.20.10 1154 1335 7.6E-4 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS21270 2052a50592c96a3ad3c5bdb29b2b98cc 3456 Gene3D G3DSA:2.160.20.10 345 617 1.1E-4 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS21270 2052a50592c96a3ad3c5bdb29b2b98cc 3456 Gene3D G3DSA:2.160.20.10 50 344 7.3E-37 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS21270 2052a50592c96a3ad3c5bdb29b2b98cc 3456 Gene3D G3DSA:2.160.20.10 636 905 3.0E-7 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS21270 2052a50592c96a3ad3c5bdb29b2b98cc 3456 Gene3D G3DSA:2.160.20.10 2007 2149 9.1E-4 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS21270 2052a50592c96a3ad3c5bdb29b2b98cc 3456 Gene3D G3DSA:2.160.20.10 988 1141 0.16 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS21270 2052a50592c96a3ad3c5bdb29b2b98cc 3456 SUPERFAMILY SSF51126 65 329 6.28E-29 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS21270 2052a50592c96a3ad3c5bdb29b2b98cc 3456 SUPERFAMILY SSF51126 387 406 6.28E-29 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS21270 2052a50592c96a3ad3c5bdb29b2b98cc 3456 Pfam PF12545 Filamentous haemagglutinin family outer membrane protein 3277 3384 3.9E-34 T 28-03-2018 IPR021026 Filamentous haemagglutinin family outer membrane protein, domain of unknown function DUF3739 MKLM6_RS21270 2052a50592c96a3ad3c5bdb29b2b98cc 3456 Pfam PF05860 haemagglutination activity domain 69 163 1.5E-16 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MKLM6_RS21270 2052a50592c96a3ad3c5bdb29b2b98cc 3456 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 86 160 3.0E-19 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MKLM6_RS13295 9f0b0373144fee84a12035fbc8ff0b15 222 Hamap MF_00428 Na(+)-translocating NADH-quinone reductase subunit D [nqrD]. 1 205 34.573 T 28-03-2018 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 MKLM6_RS13295 9f0b0373144fee84a12035fbc8ff0b15 222 PIRSF PIRSF006102 1 211 2.3E-66 T 28-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 MKLM6_RS13295 9f0b0373144fee84a12035fbc8ff0b15 222 TIGRFAM TIGR01939 nqrD: NADH:ubiquinone oxidoreductase, Na(+)-translocating, D subunit 2 205 2.9E-98 T 28-03-2018 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 MKLM6_RS13295 9f0b0373144fee84a12035fbc8ff0b15 222 Pfam PF02508 Rnf-Nqr subunit, membrane protein 7 193 7.4E-60 T 28-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 MKLM6_RS13245 e55026bd09d4facae2fa688df1957ec7 903 Gene3D G3DSA:1.10.3090.10 401 680 1.8E-36 T 28-03-2018 MKLM6_RS13245 e55026bd09d4facae2fa688df1957ec7 903 Pfam PF08335 GlnD PII-uridylyltransferase 202 342 1.5E-36 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 MKLM6_RS13245 e55026bd09d4facae2fa688df1957ec7 903 Gene3D G3DSA:3.30.460.10 60 197 4.1E-21 T 28-03-2018 MKLM6_RS13245 e55026bd09d4facae2fa688df1957ec7 903 Gene3D G3DSA:3.30.70.260 711 807 0.016 T 28-03-2018 MKLM6_RS13245 e55026bd09d4facae2fa688df1957ec7 903 SMART SM00471 475 622 2.2E-9 T 28-03-2018 IPR003607 HD/PDEase domain MKLM6_RS13245 e55026bd09d4facae2fa688df1957ec7 903 SUPERFAMILY SSF81593 223 332 5.89E-10 T 28-03-2018 MKLM6_RS13245 e55026bd09d4facae2fa688df1957ec7 903 SUPERFAMILY SSF55021 825 890 1.17E-10 T 28-03-2018 MKLM6_RS13245 e55026bd09d4facae2fa688df1957ec7 903 SUPERFAMILY SSF81301 81 195 3.53E-15 T 28-03-2018 MKLM6_RS13245 e55026bd09d4facae2fa688df1957ec7 903 Pfam PF01966 HD domain 479 609 2.0E-12 T 28-03-2018 IPR006674 HD domain MKLM6_RS13245 e55026bd09d4facae2fa688df1957ec7 903 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 41 903 283.172 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 MKLM6_RS13245 e55026bd09d4facae2fa688df1957ec7 903 PIRSF PIRSF006288 37 903 0.0 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 MKLM6_RS13245 e55026bd09d4facae2fa688df1957ec7 903 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 58 896 1.4E-273 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 MKLM6_RS13245 e55026bd09d4facae2fa688df1957ec7 903 Gene3D G3DSA:1.20.120.330 201 344 4.5E-23 T 28-03-2018 MKLM6_RS13245 e55026bd09d4facae2fa688df1957ec7 903 SUPERFAMILY SSF109604 447 586 1.63E-14 T 28-03-2018 MKLM6_RS13245 e55026bd09d4facae2fa688df1957ec7 903 Gene3D G3DSA:3.30.70.260 824 898 4.8E-9 T 28-03-2018 MKLM6_RS08550 470ed57e3cec9f211b73d45c83795e96 84 SMART SM00966 9 54 6.7E-9 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MKLM6_RS08550 470ed57e3cec9f211b73d45c83795e96 84 SUPERFAMILY SSF89447 6 67 1.1E-14 T 28-03-2018 MKLM6_RS08550 470ed57e3cec9f211b73d45c83795e96 84 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 10 51 2.0E-7 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MKLM6_RS08550 470ed57e3cec9f211b73d45c83795e96 84 Gene3D G3DSA:2.10.260.10 2 84 9.9E-16 T 28-03-2018 MKLM6_RS21675 201b45ff0c50e0ad0605cd9204359afa 395 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 168 392 2.6E-77 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 MKLM6_RS21675 201b45ff0c50e0ad0605cd9204359afa 395 Gene3D G3DSA:3.20.140.10 1 395 8.7E-94 T 28-03-2018 MKLM6_RS21675 201b45ff0c50e0ad0605cd9204359afa 395 Hamap MF_00570 Nicotinate phosphoribosyltransferase [pncB]. 1 395 44.364 T 28-03-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MKLM6_RS21675 201b45ff0c50e0ad0605cd9204359afa 395 TIGRFAM TIGR01514 NAPRTase: nicotinate phosphoribosyltransferase 4 392 3.4E-146 T 28-03-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MKLM6_RS21675 201b45ff0c50e0ad0605cd9204359afa 395 SUPERFAMILY SSF51690 119 392 6.67E-87 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MKLM6_RS21675 201b45ff0c50e0ad0605cd9204359afa 395 PIRSF PIRSF000484 1 381 1.8E-66 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 MKLM6_RS21675 201b45ff0c50e0ad0605cd9204359afa 395 SUPERFAMILY SSF54675 2 136 8.54E-34 T 28-03-2018 MKLM6_RS13900 24100d667dc2afb81d62878191d5c21a 89 Gene3D G3DSA:2.40.10.220 2 89 5.8E-11 T 28-03-2018 MKLM6_RS13900 24100d667dc2afb81d62878191d5c21a 89 SUPERFAMILY SSF141371 3 87 1.1E-6 T 28-03-2018 MKLM6_RS13900 24100d667dc2afb81d62878191d5c21a 89 Pfam PF07238 PilZ domain 4 85 5.1E-6 T 28-03-2018 IPR009875 PilZ domain GO:0035438 MKLM6_RS00795 ec73e45bfa3dd51d571ca2e250eebed8 355 Pfam PF14815 NUDIX domain 234 343 7.4E-23 T 28-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MKLM6_RS00795 ec73e45bfa3dd51d571ca2e250eebed8 355 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 191 207 6.0E-4 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 MKLM6_RS00795 ec73e45bfa3dd51d571ca2e250eebed8 355 Pfam PF00633 Helix-hairpin-helix motif 100 127 1.4E-6 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 MKLM6_RS00795 ec73e45bfa3dd51d571ca2e250eebed8 355 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 35 165 1.4E-21 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MKLM6_RS00795 ec73e45bfa3dd51d571ca2e250eebed8 355 Gene3D G3DSA:1.10.1670.10 118 224 1.2E-34 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 MKLM6_RS00795 ec73e45bfa3dd51d571ca2e250eebed8 355 SUPERFAMILY SSF48150 3 223 8.79E-73 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MKLM6_RS00795 ec73e45bfa3dd51d571ca2e250eebed8 355 SMART SM00478 39 189 2.5E-43 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MKLM6_RS00795 ec73e45bfa3dd51d571ca2e250eebed8 355 Gene3D G3DSA:3.90.79.10 230 352 1.6E-10 T 28-03-2018 MKLM6_RS00795 ec73e45bfa3dd51d571ca2e250eebed8 355 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 191 207 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MKLM6_RS00795 ec73e45bfa3dd51d571ca2e250eebed8 355 ProSitePatterns PS01155 Endonuclease III family signature. 101 128 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 MKLM6_RS00795 ec73e45bfa3dd51d571ca2e250eebed8 355 Gene3D G3DSA:1.10.340.30 21 117 5.4E-33 T 28-03-2018 MKLM6_RS00795 ec73e45bfa3dd51d571ca2e250eebed8 355 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 5 268 1.1E-109 T 28-03-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 MKLM6_RS00795 ec73e45bfa3dd51d571ca2e250eebed8 355 SUPERFAMILY SSF55811 219 342 2.88E-24 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MKLM6_RS16155 0507538248354f2f171b69584b3549fd 496 SUPERFAMILY SSF56954 54 473 1.57E-96 T 28-03-2018 MKLM6_RS16155 0507538248354f2f171b69584b3549fd 496 SUPERFAMILY SSF56954 9 21 1.57E-96 T 28-03-2018 MKLM6_RS16155 0507538248354f2f171b69584b3549fd 496 Gene3D G3DSA:1.20.1600.10 21 477 2.3E-82 T 28-03-2018 MKLM6_RS16155 0507538248354f2f171b69584b3549fd 496 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 19 471 1.0E-94 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 MKLM6_RS16155 0507538248354f2f171b69584b3549fd 496 Pfam PF02321 Outer membrane efflux protein 289 469 9.4E-21 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS16155 0507538248354f2f171b69584b3549fd 496 Pfam PF02321 Outer membrane efflux protein 63 259 4.7E-21 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS17885 616f1b66983f704a7cadbaf3dc93bb8b 142 Gene3D G3DSA:3.10.450.40 7 142 2.2E-28 T 28-03-2018 MKLM6_RS17885 616f1b66983f704a7cadbaf3dc93bb8b 142 Pfam PF04965 Gene 25-like lysozyme 40 127 2.2E-20 T 28-03-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD MKLM6_RS17885 616f1b66983f704a7cadbaf3dc93bb8b 142 SUPERFAMILY SSF160719 34 136 1.31E-25 T 28-03-2018 MKLM6_RS18645 957cb276c6cfccfea778e6283006d6a9 548 PIRSF PIRSF006630 1 246 1.0E-79 T 28-03-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MKLM6_RS18645 957cb276c6cfccfea778e6283006d6a9 548 PIRSF PIRSF006630 243 535 6.4E-116 T 28-03-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MKLM6_RS18645 957cb276c6cfccfea778e6283006d6a9 548 Pfam PF00795 Carbon-nitrogen hydrolase 5 239 2.9E-34 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS18645 957cb276c6cfccfea778e6283006d6a9 548 TIGRFAM TIGR00552 nadE: NAD+ synthetase 268 511 6.6E-59 T 28-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 MKLM6_RS18645 957cb276c6cfccfea778e6283006d6a9 548 SUPERFAMILY SSF52402 256 517 5.12E-77 T 28-03-2018 MKLM6_RS18645 957cb276c6cfccfea778e6283006d6a9 548 Pfam PF02540 NAD synthase 261 508 1.8E-74 T 28-03-2018 IPR022310 NAD/GMP synthase MKLM6_RS18645 957cb276c6cfccfea778e6283006d6a9 548 SUPERFAMILY SSF56317 3 241 5.36E-62 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS18645 957cb276c6cfccfea778e6283006d6a9 548 Gene3D G3DSA:3.60.110.10 1 243 8.8E-63 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS18645 957cb276c6cfccfea778e6283006d6a9 548 Gene3D G3DSA:3.40.50.620 259 537 2.1E-68 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS09860 d3dd1c2af743ea524157271941f0b78f 593 SUPERFAMILY SSF160246 17 165 4.18E-15 T 28-03-2018 MKLM6_RS09860 d3dd1c2af743ea524157271941f0b78f 593 Gene3D G3DSA:3.30.450.90 174 312 4.4E-44 T 28-03-2018 MKLM6_RS09860 d3dd1c2af743ea524157271941f0b78f 593 SMART SM00382 340 461 0.0014 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS09860 d3dd1c2af743ea524157271941f0b78f 593 SUPERFAMILY SSF52540 202 586 1.12E-93 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS09860 d3dd1c2af743ea524157271941f0b78f 593 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 66 168 1.9E-15 T 28-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 MKLM6_RS09860 d3dd1c2af743ea524157271941f0b78f 593 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 407 421 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 MKLM6_RS09860 d3dd1c2af743ea524157271941f0b78f 593 Gene3D G3DSA:3.40.50.300 316 593 9.6E-60 T 28-03-2018 MKLM6_RS09860 d3dd1c2af743ea524157271941f0b78f 593 Pfam PF00437 Type II/IV secretion system protein 217 479 4.5E-73 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 MKLM6_RS00635 0c87d0e414a22652d24373c49e467739 513 SUPERFAMILY SSF50615 10 94 1.28E-29 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MKLM6_RS00635 0c87d0e414a22652d24373c49e467739 513 Gene3D G3DSA:1.20.150.20 384 510 2.4E-47 T 28-03-2018 MKLM6_RS00635 0c87d0e414a22652d24373c49e467739 513 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MKLM6_RS00635 0c87d0e414a22652d24373c49e467739 513 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 512 5.7E-250 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00635 0c87d0e414a22652d24373c49e467739 513 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 375 2.4E-73 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MKLM6_RS00635 0c87d0e414a22652d24373c49e467739 513 Gene3D G3DSA:2.40.30.20 3 82 7.0E-35 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00635 0c87d0e414a22652d24373c49e467739 513 PIRSF PIRSF039088 1 513 2.3E-239 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00635 0c87d0e414a22652d24373c49e467739 513 Gene3D G3DSA:3.40.50.300 83 375 1.4E-113 T 28-03-2018 MKLM6_RS00635 0c87d0e414a22652d24373c49e467739 513 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 29 92 1.6E-15 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MKLM6_RS00635 0c87d0e414a22652d24373c49e467739 513 SUPERFAMILY SSF47917 383 511 3.4E-46 T 28-03-2018 MKLM6_RS00635 0c87d0e414a22652d24373c49e467739 513 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 512 50.435 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00635 0c87d0e414a22652d24373c49e467739 513 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 4.4E-46 T 28-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00635 0c87d0e414a22652d24373c49e467739 513 SUPERFAMILY SSF52540 96 381 7.82E-94 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SUPERFAMILY SSF51126 5173 5277 8.3E-7 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SUPERFAMILY SSF51126 5309 5400 8.3E-7 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SUPERFAMILY SSF51126 8562 8922 1.91E-13 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SUPERFAMILY SSF51126 8966 9028 1.91E-13 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SUPERFAMILY SSF49384 10665 10779 2.04E-11 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.160.20.10 7864 8084 2.8E-14 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.160.20.10 5926 6203 5.7E-9 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.160.20.10 7115 7300 2.2E-4 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.160.20.10 8085 8255 3.0E-4 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.160.20.10 6209 6526 7.5E-16 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.160.20.10 8792 9038 5.0E-11 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SUPERFAMILY SSF51120 4521 4650 2.17E-21 T 28-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.160.20.10 6913 7070 2.8E-13 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.160.20.10 5439 5589 4.6E-10 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SUPERFAMILY SSF49313 9751 9844 1.33E-6 T 28-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.160.20.10 8540 8791 2.3E-18 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.60.120.640 9858 9953 5.0E-18 T 28-03-2018 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.60.120.640 9756 9857 8.5E-20 T 28-03-2018 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.60.120.640 10050 10144 8.6E-20 T 28-03-2018 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.60.120.640 9381 9476 1.4E-19 T 28-03-2018 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.60.120.640 10145 10238 1.5E-17 T 28-03-2018 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.60.120.640 9477 9573 5.9E-22 T 28-03-2018 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.60.120.640 9954 10049 9.7E-20 T 28-03-2018 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.60.120.640 10239 10335 9.5E-18 T 28-03-2018 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 4621 4639 - T 28-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Pfam PF13229 Right handed beta helix region 5259 5391 6.3E-8 T 28-03-2018 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Pfam PF13229 Right handed beta helix region 6877 7019 3.6E-12 T 28-03-2018 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Pfam PF13229 Right handed beta helix region 6210 6344 8.9E-8 T 28-03-2018 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Pfam PF13229 Right handed beta helix region 7835 7974 2.6E-12 T 28-03-2018 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Pfam PF13229 Right handed beta helix region 8663 8812 1.9E-7 T 28-03-2018 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SUPERFAMILY SSF51126 6648 6911 8.08E-26 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.60.40.10 9574 9654 1.8E-21 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SUPERFAMILY SSF51126 7607 7865 9.2E-23 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SUPERFAMILY SSF51126 7857 8042 3.43E-10 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Pfam PF11721 Di-glucose binding within endoplasmic reticulum 7384 7480 4.6E-12 T 28-03-2018 IPR021720 Malectin Reactome: R-HSA-532668|Reactome: R-HSA-6798695 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Pfam PF11721 Di-glucose binding within endoplasmic reticulum 8339 8435 4.6E-12 T 28-03-2018 IPR021720 Malectin Reactome: R-HSA-532668|Reactome: R-HSA-6798695 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SUPERFAMILY SSF51126 6902 7088 4.0E-10 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SUPERFAMILY SSF51126 6211 6377 3.14E-10 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SUPERFAMILY SSF51126 6471 6523 3.14E-10 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SUPERFAMILY SSF51120 4353 4434 6.15E-7 T 28-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.160.20.10 6646 6912 2.5E-28 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.160.20.10 7601 7863 2.8E-24 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00722 7703 7851 37.0 T 28-03-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00722 6095 6269 12.0 T 28-03-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00722 6748 6896 37.0 T 28-03-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00722 5245 5398 12.0 T 28-03-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00722 8635 8790 11.0 T 28-03-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.160.20.10 5168 5438 3.7E-7 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SUPERFAMILY SSF51120 4449 4513 5.23E-9 T 28-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SUPERFAMILY SSF51126 5458 5598 9.87E-8 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.60.120.260 5653 5811 1.3E-10 T 28-03-2018 IPR008979 Galactose-binding domain-like MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 4390 4408 - T 28-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.40.30.20 3242 3369 0.31 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.40.30.20 3054 3119 0.0034 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.40.30.20 3195 3239 0.39 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.40.30.20 3120 3194 0.004 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SUPERFAMILY SSF49313 9572 9659 3.37E-9 T 28-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Gene3D G3DSA:2.60.40.10 9655 9747 8.4E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SUPERFAMILY SSF49299 9676 9745 9.94E-7 T 28-03-2018 IPR000601 PKD domain MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 PRINTS PR00313 NodO calcium binding signature 4570 4578 4.0E-5 T 28-03-2018 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 PRINTS PR00313 NodO calcium binding signature 4625 4634 4.0E-5 T 28-03-2018 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 PRINTS PR00313 NodO calcium binding signature 4540 4551 4.0E-5 T 28-03-2018 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 PRINTS PR00313 NodO calcium binding signature 4616 4624 4.0E-5 T 28-03-2018 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 8672 8694 46.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 8647 8668 1900.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 7690 7711 1200.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 6249 6270 8400.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 6854 6875 2600.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 6735 6756 1200.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 6805 6826 1800.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 6938 6957 8900.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 7893 7912 8900.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 8850 8872 6.9 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 6876 6897 950.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 8810 8832 1800.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 7715 7736 670.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 7643 7665 2400.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 6334 6356 940.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 1061 1097 6300.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 5485 5507 1600.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 5351 5372 970.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 6827 6849 1200.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 5329 5350 1000.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 8696 8718 10000.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 8745 8767 2.6 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 7010 7031 1100.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 7940 7963 270.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 4337 4372 5300.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 7760 7781 1800.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 5308 5328 530.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 8598 8620 1200.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 7913 7935 1.1 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 6120 6149 4400.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 5227 5253 5800.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 8902 8924 1600.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 8987 9014 9400.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 6916 6937 630.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 5462 5483 190.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 6172 6193 880.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 7871 7892 630.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 5532 5564 9200.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 5508 5530 54.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 6958 6980 1.1 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 2314 2344 2700.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 6058 6079 2100.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 2981 3007 6100.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 6760 6781 670.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 6985 7008 270.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 7831 7852 950.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 8719 8741 45.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 7965 7986 1100.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 7809 7830 2600.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 6288 6309 370.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SMART SM00710 7782 7804 1200.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 4524 4541 1.8 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 4393 4410 0.33 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 4616 4632 0.14 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 4422 4433 33.0 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 4490 4506 2.7 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 4543 4559 0.12 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 4588 4605 0.74 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 4472 4487 0.81 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 4669 4685 1.3 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 4562 4577 52.0 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 SUPERFAMILY SSF51126 5960 6218 1.06E-11 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS10960 702561c17028a0a22f3decf887a35ee4 10854 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 4530 4548 - T 28-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site MKLM6_RS12580 ee3d5e431b2166b8c5b8348cd68490ed 370 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 1 197 2.3E-74 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MKLM6_RS12580 ee3d5e431b2166b8c5b8348cd68490ed 370 PIRSF PIRSF001259 1 369 8.0E-133 T 28-03-2018 MKLM6_RS12580 ee3d5e431b2166b8c5b8348cd68490ed 370 SUPERFAMILY SSF142695 203 366 1.83E-47 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 MKLM6_RS12580 ee3d5e431b2166b8c5b8348cd68490ed 370 Gene3D G3DSA:3.90.870.10 1 210 1.3E-94 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain MKLM6_RS12580 ee3d5e431b2166b8c5b8348cd68490ed 370 Pfam PF00925 GTP cyclohydrolase II 206 366 6.3E-42 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 MKLM6_RS12580 ee3d5e431b2166b8c5b8348cd68490ed 370 SUPERFAMILY SSF55821 2 201 2.52E-86 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain MKLM6_RS12580 ee3d5e431b2166b8c5b8348cd68490ed 370 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 201 37.749 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MKLM6_RS12580 ee3d5e431b2166b8c5b8348cd68490ed 370 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 5 196 1.4E-83 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MKLM6_RS03230 0d3410a1b25229cb0627ab4335c56cdf 300 TIGRFAM TIGR04215 choice_anch_A: choice-of-anchor A domain 30 268 7.7E-58 T 28-03-2018 IPR026588 Choice-of-anchor A domain MKLM6_RS08680 71aff2815fff801f3773e45486ccb9ff 231 Pfam PF13500 AAA domain 4 205 8.1E-36 T 28-03-2018 MKLM6_RS08680 71aff2815fff801f3773e45486ccb9ff 231 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 173 5.4E-46 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MKLM6_RS08680 71aff2815fff801f3773e45486ccb9ff 231 PIRSF PIRSF006755 1 218 2.1E-63 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MKLM6_RS08680 71aff2815fff801f3773e45486ccb9ff 231 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 2 206 26.599 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MKLM6_RS08680 71aff2815fff801f3773e45486ccb9ff 231 Gene3D G3DSA:3.40.50.300 3 211 1.0E-55 T 28-03-2018 MKLM6_RS08680 71aff2815fff801f3773e45486ccb9ff 231 SUPERFAMILY SSF52540 1 207 2.21E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS05545 8419956f12cf576b0af5225e481fcf1d 714 Pfam PF00563 EAL domain 448 683 4.9E-69 T 28-03-2018 IPR001633 EAL domain MKLM6_RS05545 8419956f12cf576b0af5225e481fcf1d 714 Gene3D G3DSA:3.30.450.20 27 176 1.6E-4 T 28-03-2018 MKLM6_RS05545 8419956f12cf576b0af5225e481fcf1d 714 SMART SM00267 253 430 7.0E-59 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS05545 8419956f12cf576b0af5225e481fcf1d 714 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 260 428 7.9E-44 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS05545 8419956f12cf576b0af5225e481fcf1d 714 SUPERFAMILY SSF141868 445 698 1.7E-84 T 28-03-2018 IPR001633 EAL domain MKLM6_RS05545 8419956f12cf576b0af5225e481fcf1d 714 Gene3D G3DSA:3.30.70.270 258 436 7.0E-62 T 28-03-2018 MKLM6_RS05545 8419956f12cf576b0af5225e481fcf1d 714 SMART SM00052 440 688 1.3E-108 T 28-03-2018 IPR001633 EAL domain MKLM6_RS05545 8419956f12cf576b0af5225e481fcf1d 714 Pfam PF00990 Diguanylate cyclase, GGDEF domain 264 426 3.9E-50 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS05545 8419956f12cf576b0af5225e481fcf1d 714 Gene3D G3DSA:3.20.20.450 437 692 1.6E-93 T 28-03-2018 IPR001633 EAL domain MKLM6_RS05545 8419956f12cf576b0af5225e481fcf1d 714 SUPERFAMILY SSF55073 269 432 1.49E-50 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS19970 044a1bfd93d0c8ca91d794504f11a018 435 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 2 435 3.4E-169 T 28-03-2018 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 MKLM6_RS19970 044a1bfd93d0c8ca91d794504f11a018 435 Pfam PF02817 e3 binding domain 138 173 5.5E-14 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MKLM6_RS19970 044a1bfd93d0c8ca91d794504f11a018 435 SUPERFAMILY SSF52777 194 435 7.12E-79 T 28-03-2018 MKLM6_RS19970 044a1bfd93d0c8ca91d794504f11a018 435 Gene3D G3DSA:3.30.559.10 193 435 1.2E-77 T 28-03-2018 MKLM6_RS19970 044a1bfd93d0c8ca91d794504f11a018 435 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MKLM6_RS19970 044a1bfd93d0c8ca91d794504f11a018 435 SUPERFAMILY SSF51230 3 97 1.33E-22 T 28-03-2018 IPR011053 Single hybrid motif MKLM6_RS19970 044a1bfd93d0c8ca91d794504f11a018 435 SUPERFAMILY SSF47005 133 178 1.12E-9 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MKLM6_RS19970 044a1bfd93d0c8ca91d794504f11a018 435 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 206 435 4.7E-75 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MKLM6_RS19970 044a1bfd93d0c8ca91d794504f11a018 435 Gene3D G3DSA:3.90.1170.30 64 98 2.6E-4 T 28-03-2018 MKLM6_RS19970 044a1bfd93d0c8ca91d794504f11a018 435 Gene3D G3DSA:4.10.320.10 131 186 1.4E-17 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MKLM6_RS19970 044a1bfd93d0c8ca91d794504f11a018 435 Pfam PF00364 Biotin-requiring enzyme 6 76 2.4E-17 T 28-03-2018 IPR000089 Biotin/lipoyl attachment MKLM6_RS19970 044a1bfd93d0c8ca91d794504f11a018 435 Gene3D G3DSA:2.40.50.100 4 63 5.1E-13 T 28-03-2018 MKLM6_RS10985 53c2a4453a0d441a690c670dfda99894 391 Gene3D G3DSA:1.20.1600.10 184 360 2.0E-11 T 28-03-2018 MKLM6_RS10985 53c2a4453a0d441a690c670dfda99894 391 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 141 389 8.4E-36 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MKLM6_RS10985 53c2a4453a0d441a690c670dfda99894 391 Gene3D G3DSA:2.40.50.100 53 183 2.7E-5 T 28-03-2018 MKLM6_RS10985 53c2a4453a0d441a690c670dfda99894 391 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 153 379 2.8E-16 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MKLM6_RS10985 53c2a4453a0d441a690c670dfda99894 391 SUPERFAMILY SSF111369 150 389 2.88E-24 T 28-03-2018 MKLM6_RS18315 99697a5ea6bc17a8b331b63488f8ffd8 335 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 24 317 3.2E-112 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18315 99697a5ea6bc17a8b331b63488f8ffd8 335 Gene3D G3DSA:1.10.150.20 246 329 1.7E-27 T 28-03-2018 MKLM6_RS18315 99697a5ea6bc17a8b331b63488f8ffd8 335 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 252 309 2.4E-22 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18315 99697a5ea6bc17a8b331b63488f8ffd8 335 SUPERFAMILY SSF56553 53 176 1.05E-42 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18315 99697a5ea6bc17a8b331b63488f8ffd8 335 Gene3D G3DSA:3.30.1360.10 111 229 9.0E-27 T 28-03-2018 MKLM6_RS18315 99697a5ea6bc17a8b331b63488f8ffd8 335 Gene3D G3DSA:3.30.1360.10 5 95 1.6E-18 T 28-03-2018 MKLM6_RS18315 99697a5ea6bc17a8b331b63488f8ffd8 335 SMART SM00662 23 232 3.6E-91 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18315 99697a5ea6bc17a8b331b63488f8ffd8 335 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 63 155 2.1E-25 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18315 99697a5ea6bc17a8b331b63488f8ffd8 335 SUPERFAMILY SSF55257 177 231 2.36E-29 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18315 99697a5ea6bc17a8b331b63488f8ffd8 335 SUPERFAMILY SSF55257 9 53 2.36E-29 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18315 99697a5ea6bc17a8b331b63488f8ffd8 335 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 5 318 35.712 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18315 99697a5ea6bc17a8b331b63488f8ffd8 335 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 29 226 3.8E-22 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18315 99697a5ea6bc17a8b331b63488f8ffd8 335 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 257 327 6.0E-32 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18315 99697a5ea6bc17a8b331b63488f8ffd8 335 SUPERFAMILY SSF47789 252 327 7.19E-25 T 28-03-2018 MKLM6_RS07565 307912b7910f55205b65653ed70e112d 1014 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 1.2E-36 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS07565 307912b7910f55205b65653ed70e112d 1014 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 1.2E-36 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS07565 307912b7910f55205b65653ed70e112d 1014 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 1.2E-36 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS07565 307912b7910f55205b65653ed70e112d 1014 PRINTS PR00702 Acriflavin resistance protein family signature 469 492 1.2E-36 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS07565 307912b7910f55205b65653ed70e112d 1014 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 1.2E-36 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS07565 307912b7910f55205b65653ed70e112d 1014 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 1.2E-36 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS07565 307912b7910f55205b65653ed70e112d 1014 Gene3D G3DSA:1.20.1640.10 799 1014 2.7E-28 T 28-03-2018 MKLM6_RS07565 307912b7910f55205b65653ed70e112d 1014 SUPERFAMILY SSF82714 183 264 5.1E-13 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS07565 307912b7910f55205b65653ed70e112d 1014 SUPERFAMILY SSF82714 708 792 4.45E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS07565 307912b7910f55205b65653ed70e112d 1014 Gene3D G3DSA:3.30.2090.10 181 267 4.0E-16 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS07565 307912b7910f55205b65653ed70e112d 1014 SUPERFAMILY SSF82693 41 129 1.05E-19 T 28-03-2018 MKLM6_RS07565 307912b7910f55205b65653ed70e112d 1014 SUPERFAMILY SSF82866 791 1013 6.8E-37 T 28-03-2018 MKLM6_RS07565 307912b7910f55205b65653ed70e112d 1014 Gene3D G3DSA:3.30.70.1430 42 140 5.2E-21 T 28-03-2018 MKLM6_RS07565 307912b7910f55205b65653ed70e112d 1014 Gene3D G3DSA:3.30.70.1430 560 707 4.2E-7 T 28-03-2018 MKLM6_RS07565 307912b7910f55205b65653ed70e112d 1014 Pfam PF00873 AcrB/AcrD/AcrF family 5 1013 4.6E-226 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS07565 307912b7910f55205b65653ed70e112d 1014 Gene3D G3DSA:1.20.1640.10 282 508 1.9E-35 T 28-03-2018 MKLM6_RS07565 307912b7910f55205b65653ed70e112d 1014 SUPERFAMILY SSF82693 142 182 7.32E-13 T 28-03-2018 MKLM6_RS07565 307912b7910f55205b65653ed70e112d 1014 SUPERFAMILY SSF82693 268 311 7.32E-13 T 28-03-2018 MKLM6_RS07565 307912b7910f55205b65653ed70e112d 1014 Gene3D G3DSA:3.30.2090.10 708 794 2.2E-16 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS07565 307912b7910f55205b65653ed70e112d 1014 SUPERFAMILY SSF82866 292 494 3.53E-36 T 28-03-2018 MKLM6_RS17620 1b22fc6b2bb42d463f5e65c6d66fffe0 91 PIRSF PIRSF003113 1 91 4.5E-29 T 28-03-2018 IPR002634 BolA protein MKLM6_RS17620 1b22fc6b2bb42d463f5e65c6d66fffe0 91 SUPERFAMILY SSF82657 1 88 8.89E-28 T 28-03-2018 IPR002634 BolA protein MKLM6_RS17620 1b22fc6b2bb42d463f5e65c6d66fffe0 91 Pfam PF01722 BolA-like protein 10 85 6.6E-29 T 28-03-2018 IPR002634 BolA protein MKLM6_RS17620 1b22fc6b2bb42d463f5e65c6d66fffe0 91 Gene3D G3DSA:3.30.300.90 1 91 2.5E-27 T 28-03-2018 MKLM6_RS14175 db21ee4b8238d1c4f505534a82af5669 73 Pfam PF12697 Alpha/beta hydrolase family 2 73 4.1E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS14175 db21ee4b8238d1c4f505534a82af5669 73 Gene3D G3DSA:3.40.50.1820 1 73 1.3E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS14175 db21ee4b8238d1c4f505534a82af5669 73 SUPERFAMILY SSF53474 1 73 5.75E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS19130 b3fa8e3aa7a16f86f1aaf971ee9d1102 181 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 36.362 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MKLM6_RS19130 b3fa8e3aa7a16f86f1aaf971ee9d1102 181 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MKLM6_RS19130 b3fa8e3aa7a16f86f1aaf971ee9d1102 181 Pfam PF00719 Inorganic pyrophosphatase 18 174 7.9E-53 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MKLM6_RS19130 b3fa8e3aa7a16f86f1aaf971ee9d1102 181 SUPERFAMILY SSF50324 3 175 7.2E-66 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MKLM6_RS19130 b3fa8e3aa7a16f86f1aaf971ee9d1102 181 Gene3D G3DSA:3.90.80.10 1 180 5.3E-54 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MKLM6_RS22745 33be3b3e4d86ef2ef935168a2b11c532 302 SUPERFAMILY SSF52540 16 300 1.66E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS22745 33be3b3e4d86ef2ef935168a2b11c532 302 Pfam PF13614 AAA domain 16 206 2.1E-22 T 28-03-2018 IPR025669 AAA domain MKLM6_RS22745 33be3b3e4d86ef2ef935168a2b11c532 302 Gene3D G3DSA:3.40.50.300 15 302 3.2E-34 T 28-03-2018 MKLM6_RS01765 1e1038b87b9b27d02e3d6e8e8f9bd69e 113 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 77 111 2.3E-12 T 28-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 MKLM6_RS01765 1e1038b87b9b27d02e3d6e8e8f9bd69e 113 SUPERFAMILY SSF109635 3 78 1.83E-5 T 28-03-2018 MKLM6_RS01765 1e1038b87b9b27d02e3d6e8e8f9bd69e 113 SUPERFAMILY SSF57716 79 110 3.53E-8 T 28-03-2018 MKLM6_RS20325 5058c8030fefd229f2daf0968e248a21 463 Gene3D G3DSA:2.60.200.20 5 104 5.0E-14 T 28-03-2018 MKLM6_RS20325 5058c8030fefd229f2daf0968e248a21 463 Pfam PF00498 FHA domain 29 96 2.0E-10 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MKLM6_RS20325 5058c8030fefd229f2daf0968e248a21 463 SUPERFAMILY SSF49879 22 113 1.51E-15 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MKLM6_RS20325 5058c8030fefd229f2daf0968e248a21 463 TIGRFAM TIGR03354 VI_FHA: type VI secretion system FHA domain protein 3 457 1.8E-89 T 28-03-2018 IPR017735 Type VI secretion system, FHA domain-containing protein MKLM6_RS11065 6bcb42b648d1643c157b16fbec887c18 142 Pfam PF03459 TOBE domain 3 66 1.6E-17 T 28-03-2018 IPR005116 Transport-associated OB, type 1 MKLM6_RS11065 6bcb42b648d1643c157b16fbec887c18 142 Pfam PF03459 TOBE domain 76 138 4.5E-16 T 28-03-2018 IPR005116 Transport-associated OB, type 1 MKLM6_RS11065 6bcb42b648d1643c157b16fbec887c18 142 SUPERFAMILY SSF50331 2 69 8.99E-20 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal MKLM6_RS11065 6bcb42b648d1643c157b16fbec887c18 142 SUPERFAMILY SSF50331 74 140 1.56E-19 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal MKLM6_RS11065 6bcb42b648d1643c157b16fbec887c18 142 Gene3D G3DSA:2.40.50.100 1 69 1.0E-20 T 28-03-2018 MKLM6_RS11065 6bcb42b648d1643c157b16fbec887c18 142 Gene3D G3DSA:2.40.50.100 73 141 1.3E-20 T 28-03-2018 MKLM6_RS11065 6bcb42b648d1643c157b16fbec887c18 142 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 1 68 6.8E-24 T 28-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 MKLM6_RS11065 6bcb42b648d1643c157b16fbec887c18 142 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 73 140 1.0E-21 T 28-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 MKLM6_RS07200 dd8d8aad51de845f54463b06f04743fe 233 Hamap MF_00201 DNA repair protein RecO [recO]. 5 229 21.823 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MKLM6_RS07200 dd8d8aad51de845f54463b06f04743fe 233 Pfam PF11967 Recombination protein O N terminal 9 82 1.6E-20 T 28-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal MKLM6_RS07200 dd8d8aad51de845f54463b06f04743fe 233 Gene3D G3DSA:3.40.50.880 131 227 2.3E-4 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS07200 dd8d8aad51de845f54463b06f04743fe 233 TIGRFAM TIGR00613 reco: DNA repair protein RecO 11 152 2.1E-29 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MKLM6_RS07200 dd8d8aad51de845f54463b06f04743fe 233 SUPERFAMILY SSF57863 88 214 5.23E-9 T 28-03-2018 MKLM6_RS07200 dd8d8aad51de845f54463b06f04743fe 233 SUPERFAMILY SSF50249 6 82 5.14E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS07200 dd8d8aad51de845f54463b06f04743fe 233 Pfam PF02565 Recombination protein O C terminal 86 223 6.5E-20 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MKLM6_RS07200 dd8d8aad51de845f54463b06f04743fe 233 Gene3D G3DSA:2.40.50.140 4 84 4.3E-23 T 28-03-2018 MKLM6_RS10880 0d853cc9d8de79a8c2350de4f99b2c80 55 TIGRFAM TIGR03141 cytochro_ccmD: heme exporter protein CcmD 7 52 9.1E-21 T 28-03-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 MKLM6_RS10880 0d853cc9d8de79a8c2350de4f99b2c80 55 Pfam PF04995 Heme exporter protein D (CcmD) 10 53 1.2E-19 T 28-03-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 MKLM6_RS13690 03fa17e58bf4f97db999f95651fa7ded 421 Pfam PF00534 Glycosyl transferases group 1 284 399 1.2E-7 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 MKLM6_RS13690 03fa17e58bf4f97db999f95651fa7ded 421 SUPERFAMILY SSF53756 57 416 5.1E-16 T 28-03-2018 MKLM6_RS13690 03fa17e58bf4f97db999f95651fa7ded 421 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 33 209 9.3E-65 T 28-03-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 MKLM6_RS13690 03fa17e58bf4f97db999f95651fa7ded 421 Gene3D G3DSA:3.40.50.2000 24 404 1.9E-16 T 28-03-2018 MKLM6_RS13760 70f774af2a61786bbb898022661ee84e 459 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 215 230 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MKLM6_RS13760 70f774af2a61786bbb898022661ee84e 459 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 153 166 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MKLM6_RS13760 70f774af2a61786bbb898022661ee84e 459 Gene3D G3DSA:1.10.8.60 302 371 1.2E-20 T 28-03-2018 MKLM6_RS13760 70f774af2a61786bbb898022661ee84e 459 SUPERFAMILY SSF52540 132 369 2.13E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS13760 70f774af2a61786bbb898022661ee84e 459 Gene3D G3DSA:3.40.50.2300 1 137 9.0E-35 T 28-03-2018 MKLM6_RS13760 70f774af2a61786bbb898022661ee84e 459 SUPERFAMILY SSF46689 341 450 6.27E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS13760 70f774af2a61786bbb898022661ee84e 459 SMART SM00448 4 115 6.3E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS13760 70f774af2a61786bbb898022661ee84e 459 Gene3D G3DSA:1.10.10.60 399 451 1.0E-9 T 28-03-2018 MKLM6_RS13760 70f774af2a61786bbb898022661ee84e 459 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 341 350 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site MKLM6_RS13760 70f774af2a61786bbb898022661ee84e 459 SMART SM00382 149 292 7.1E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS13760 70f774af2a61786bbb898022661ee84e 459 Gene3D G3DSA:3.40.50.300 138 301 1.3E-25 T 28-03-2018 MKLM6_RS13760 70f774af2a61786bbb898022661ee84e 459 Pfam PF00072 Response regulator receiver domain 6 115 2.3E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS13760 70f774af2a61786bbb898022661ee84e 459 Pfam PF02954 Bacterial regulatory protein, Fis family 411 449 1.7E-8 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS13760 70f774af2a61786bbb898022661ee84e 459 SUPERFAMILY SSF52172 1 174 6.97E-42 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS13760 70f774af2a61786bbb898022661ee84e 459 Pfam PF00158 Sigma-54 interaction domain 132 295 2.4E-63 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MKLM6_RS10315 d1326c34022e6eeb179e6086291cbce4 736 PRINTS PR00344 Bacterial sensor protein C-terminal signature 490 504 1.3E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS10315 d1326c34022e6eeb179e6086291cbce4 736 PRINTS PR00344 Bacterial sensor protein C-terminal signature 546 564 1.3E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS10315 d1326c34022e6eeb179e6086291cbce4 736 PRINTS PR00344 Bacterial sensor protein C-terminal signature 570 583 1.3E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS10315 d1326c34022e6eeb179e6086291cbce4 736 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 447 585 5.1E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS10315 d1326c34022e6eeb179e6086291cbce4 736 SMART SM00073 4 101 9.2E-28 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS10315 d1326c34022e6eeb179e6086291cbce4 736 Pfam PF01584 CheW-like domain 592 718 1.8E-27 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS10315 d1326c34022e6eeb179e6086291cbce4 736 Pfam PF01627 Hpt domain 8 92 5.8E-17 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS10315 d1326c34022e6eeb179e6086291cbce4 736 Gene3D G3DSA:1.10.287.560 340 399 1.1E-10 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 MKLM6_RS10315 d1326c34022e6eeb179e6086291cbce4 736 SUPERFAMILY SSF50341 585 716 2.88E-33 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS10315 d1326c34022e6eeb179e6086291cbce4 736 Gene3D G3DSA:2.40.50.180 600 669 6.0E-15 T 28-03-2018 MKLM6_RS10315 d1326c34022e6eeb179e6086291cbce4 736 SMART SM00260 578 716 3.1E-39 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS10315 d1326c34022e6eeb179e6086291cbce4 736 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 342 401 1.2E-8 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 MKLM6_RS10315 d1326c34022e6eeb179e6086291cbce4 736 Gene3D G3DSA:3.30.565.10 400 587 5.0E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS10315 d1326c34022e6eeb179e6086291cbce4 736 SMART SM01231 340 400 2.0E-10 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 MKLM6_RS10315 d1326c34022e6eeb179e6086291cbce4 736 SUPERFAMILY SSF47226 5 104 1.7E-26 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS10315 d1326c34022e6eeb179e6086291cbce4 736 SUPERFAMILY SSF47384 341 401 8.24E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS10315 d1326c34022e6eeb179e6086291cbce4 736 Gene3D G3DSA:1.20.120.160 1 147 2.6E-28 T 28-03-2018 MKLM6_RS10315 d1326c34022e6eeb179e6086291cbce4 736 SMART SM00387 445 586 1.3E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS10315 d1326c34022e6eeb179e6086291cbce4 736 Gene3D G3DSA:2.30.30.40 670 716 3.0E-20 T 28-03-2018 MKLM6_RS10315 d1326c34022e6eeb179e6086291cbce4 736 SUPERFAMILY SSF55874 402 584 1.44E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS18030 2dad7c931a2093e9b11efe916b2267ac 212 SUPERFAMILY SSF51161 70 204 1.8E-39 T 28-03-2018 IPR011004 Trimeric LpxA-like MKLM6_RS18030 2dad7c931a2093e9b11efe916b2267ac 212 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 5 205 1.5E-63 T 28-03-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like MKLM6_RS18030 2dad7c931a2093e9b11efe916b2267ac 212 Gene3D G3DSA:2.160.10.10 90 211 5.5E-30 T 28-03-2018 MKLM6_RS18030 2dad7c931a2093e9b11efe916b2267ac 212 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 160 194 1.5E-6 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS18030 2dad7c931a2093e9b11efe916b2267ac 212 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 124 158 8.4E-8 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS18030 2dad7c931a2093e9b11efe916b2267ac 212 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 168 196 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MKLM6_RS18030 2dad7c931a2093e9b11efe916b2267ac 212 Gene3D G3DSA:3.40.50.20 1 89 2.0E-12 T 28-03-2018 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 Gene3D G3DSA:1.20.1110.10 520 848 7.7E-53 T 28-03-2018 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 SUPERFAMILY SSF81665 647 849 2.22E-97 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 SUPERFAMILY SSF81665 235 328 2.22E-97 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 SUPERFAMILY SSF81665 15 125 2.22E-97 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 SMART SM00831 14 87 2.6E-20 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 569 688 1.4E-25 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 94 441 5.8E-39 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 PRINTS PR01836 Magnesium-transporting ATPase signature 368 381 3.9E-46 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 PRINTS PR01836 Magnesium-transporting ATPase signature 247 263 3.9E-46 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 PRINTS PR01836 Magnesium-transporting ATPase signature 656 671 3.9E-46 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 PRINTS PR01836 Magnesium-transporting ATPase signature 674 685 3.9E-46 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 PRINTS PR01836 Magnesium-transporting ATPase signature 706 719 3.9E-46 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 PRINTS PR01836 Magnesium-transporting ATPase signature 726 742 3.9E-46 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 PRINTS PR01836 Magnesium-transporting ATPase signature 757 778 3.9E-46 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 PRINTS PR01836 Magnesium-transporting ATPase signature 806 827 3.9E-46 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 PRINTS PR01836 Magnesium-transporting ATPase signature 264 283 3.9E-46 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 Pfam PF00689 Cation transporting ATPase, C-terminus 681 843 1.5E-17 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 Pfam PF00690 Cation transporter/ATPase, N-terminus 15 82 6.8E-15 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 336 342 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 Gene3D G3DSA:2.70.150.10 22 236 1.0E-41 T 28-03-2018 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 28 846 2.7E-274 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 SUPERFAMILY SSF81653 125 234 4.71E-28 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 Pfam PF00122 E1-E2 ATPase 124 314 8.9E-45 T 28-03-2018 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 Gene3D G3DSA:3.40.1110.10 296 505 8.0E-36 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 Pfam PF00702 haloacid dehalogenase-like hydrolase 330 612 3.3E-13 T 28-03-2018 MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 SUPERFAMILY SSF56784 332 352 3.57E-37 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS09720 4a2c58cccfa8c1ca9a9a5dbeb5184bd8 869 SUPERFAMILY SSF56784 454 698 3.57E-37 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS07320 2c899e74bfdf76e9be7e92002349630e 765 Pfam PF07715 TonB-dependent Receptor Plug Domain 47 159 9.3E-13 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS07320 2c899e74bfdf76e9be7e92002349630e 765 Gene3D G3DSA:2.40.170.20 172 764 1.3E-78 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS07320 2c899e74bfdf76e9be7e92002349630e 765 SUPERFAMILY SSF56935 22 763 2.17E-101 T 28-03-2018 MKLM6_RS07320 2c899e74bfdf76e9be7e92002349630e 765 Pfam PF00593 TonB dependent receptor 256 763 2.0E-50 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS07320 2c899e74bfdf76e9be7e92002349630e 765 Gene3D G3DSA:2.170.130.10 20 171 9.4E-17 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS07920 9247b47562e27f69de28ddb634736371 1057 SUPERFAMILY SSF82714 730 819 2.35E-5 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS07920 9247b47562e27f69de28ddb634736371 1057 SUPERFAMILY SSF82714 182 264 1.57E-12 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS07920 9247b47562e27f69de28ddb634736371 1057 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 1.0E-33 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS07920 9247b47562e27f69de28ddb634736371 1057 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.0E-33 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS07920 9247b47562e27f69de28ddb634736371 1057 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.0E-33 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS07920 9247b47562e27f69de28ddb634736371 1057 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 1.0E-33 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS07920 9247b47562e27f69de28ddb634736371 1057 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 1.0E-33 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS07920 9247b47562e27f69de28ddb634736371 1057 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 1.0E-33 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS07920 9247b47562e27f69de28ddb634736371 1057 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 1.0E-33 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS07920 9247b47562e27f69de28ddb634736371 1057 Gene3D G3DSA:3.30.70.1430 568 679 2.0E-10 T 28-03-2018 MKLM6_RS07920 9247b47562e27f69de28ddb634736371 1057 Gene3D G3DSA:1.20.1640.10 282 495 1.2E-35 T 28-03-2018 MKLM6_RS07920 9247b47562e27f69de28ddb634736371 1057 Gene3D G3DSA:1.20.1640.10 838 1052 1.5E-30 T 28-03-2018 MKLM6_RS07920 9247b47562e27f69de28ddb634736371 1057 Gene3D G3DSA:3.30.70.1430 40 140 4.2E-19 T 28-03-2018 MKLM6_RS07920 9247b47562e27f69de28ddb634736371 1057 Pfam PF00873 AcrB/AcrD/AcrF family 3 1041 5.0E-205 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS07920 9247b47562e27f69de28ddb634736371 1057 SUPERFAMILY SSF82866 823 1045 1.96E-46 T 28-03-2018 MKLM6_RS07920 9247b47562e27f69de28ddb634736371 1057 SUPERFAMILY SSF82693 40 133 8.89E-18 T 28-03-2018 MKLM6_RS07920 9247b47562e27f69de28ddb634736371 1057 SUPERFAMILY SSF82866 291 488 9.94E-40 T 28-03-2018 MKLM6_RS07920 9247b47562e27f69de28ddb634736371 1057 SUPERFAMILY SSF82693 267 323 6.8E-14 T 28-03-2018 MKLM6_RS07920 9247b47562e27f69de28ddb634736371 1057 SUPERFAMILY SSF82693 135 181 6.8E-14 T 28-03-2018 MKLM6_RS07920 9247b47562e27f69de28ddb634736371 1057 Gene3D G3DSA:3.30.2090.10 728 821 2.1E-9 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS07920 9247b47562e27f69de28ddb634736371 1057 Gene3D G3DSA:3.30.2090.10 180 267 3.2E-11 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS06555 5b7b1eed47738078ad54159c1cf41edc 421 Gene3D G3DSA:3.50.50.60 11 170 9.1E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS06555 5b7b1eed47738078ad54159c1cf41edc 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 14 33 4.8E-6 T 28-03-2018 MKLM6_RS06555 5b7b1eed47738078ad54159c1cf41edc 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 4.8E-6 T 28-03-2018 MKLM6_RS06555 5b7b1eed47738078ad54159c1cf41edc 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 130 148 4.8E-6 T 28-03-2018 MKLM6_RS06555 5b7b1eed47738078ad54159c1cf41edc 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 13 35 4.3E-7 T 28-03-2018 MKLM6_RS06555 5b7b1eed47738078ad54159c1cf41edc 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 133 142 4.3E-7 T 28-03-2018 MKLM6_RS06555 5b7b1eed47738078ad54159c1cf41edc 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 4.3E-7 T 28-03-2018 MKLM6_RS06555 5b7b1eed47738078ad54159c1cf41edc 421 SUPERFAMILY SSF51905 155 211 2.19E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS06555 5b7b1eed47738078ad54159c1cf41edc 421 SUPERFAMILY SSF51905 293 399 2.19E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS06555 5b7b1eed47738078ad54159c1cf41edc 421 Gene3D G3DSA:3.50.50.60 172 420 2.0E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS06555 5b7b1eed47738078ad54159c1cf41edc 421 SUPERFAMILY SSF51905 15 215 3.52E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS06555 5b7b1eed47738078ad54159c1cf41edc 421 TIGRFAM TIGR04046 MSMEG_0569_nitr: flavin-dependent oxidoreductase, MSMEG_0569 family 13 411 7.6E-194 T 28-03-2018 IPR024000 Conserved hypothetical protein CHP04046, FMN-dependent MKLM6_RS06555 5b7b1eed47738078ad54159c1cf41edc 421 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 15 208 2.6E-25 T 28-03-2018 MKLM6_RS17130 4d1b5205c3d2497fc046a976ffc2361b 370 Gene3D G3DSA:3.40.1710.10 38 190 7.7E-28 T 28-03-2018 MKLM6_RS17130 4d1b5205c3d2497fc046a976ffc2361b 370 Pfam PF12698 ABC-2 family transporter protein 26 359 4.5E-37 T 28-03-2018 MKLM6_RS15660 b37d5c4047d6b2eb515cdd87d7d2a86c 247 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 5 244 1.4E-78 T 28-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 MKLM6_RS15660 b37d5c4047d6b2eb515cdd87d7d2a86c 247 Gene3D G3DSA:3.30.1330.30 1 76 3.4E-15 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like MKLM6_RS15660 b37d5c4047d6b2eb515cdd87d7d2a86c 247 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 6 76 6.9E-17 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MKLM6_RS15660 b37d5c4047d6b2eb515cdd87d7d2a86c 247 SUPERFAMILY SSF55315 3 76 1.77E-16 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like MKLM6_RS15660 b37d5c4047d6b2eb515cdd87d7d2a86c 247 Gene3D G3DSA:3.40.1280.10 77 247 1.5E-49 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MKLM6_RS15660 b37d5c4047d6b2eb515cdd87d7d2a86c 247 SUPERFAMILY SSF75217 94 244 1.77E-49 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases MKLM6_RS15660 b37d5c4047d6b2eb515cdd87d7d2a86c 247 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 3 245 39.794 T 28-03-2018 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB MKLM6_RS15660 b37d5c4047d6b2eb515cdd87d7d2a86c 247 SMART SM00967 5 81 1.7E-15 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MKLM6_RS15660 b37d5c4047d6b2eb515cdd87d7d2a86c 247 Pfam PF00588 SpoU rRNA Methylase family 98 238 4.7E-42 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MKLM6_RS21300 f8b26156e9f470692657bf6400e0e7d8 957 Gene3D G3DSA:3.20.20.450 690 940 8.8E-101 T 28-03-2018 IPR001633 EAL domain MKLM6_RS21300 f8b26156e9f470692657bf6400e0e7d8 957 SUPERFAMILY SSF141868 697 943 1.96E-90 T 28-03-2018 IPR001633 EAL domain MKLM6_RS21300 f8b26156e9f470692657bf6400e0e7d8 957 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 515 678 7.5E-44 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS21300 f8b26156e9f470692657bf6400e0e7d8 957 Gene3D G3DSA:3.30.450.40 318 518 2.8E-12 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS21300 f8b26156e9f470692657bf6400e0e7d8 957 Pfam PF00672 HAMP domain 300 345 5.7E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS21300 f8b26156e9f470692657bf6400e0e7d8 957 SUPERFAMILY SSF55781 367 517 4.58E-8 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS21300 f8b26156e9f470692657bf6400e0e7d8 957 Pfam PF00990 Diguanylate cyclase, GGDEF domain 517 676 6.8E-50 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS21300 f8b26156e9f470692657bf6400e0e7d8 957 Gene3D G3DSA:3.30.70.270 519 689 2.5E-60 T 28-03-2018 MKLM6_RS21300 f8b26156e9f470692657bf6400e0e7d8 957 SUPERFAMILY SSF55073 522 684 7.85E-50 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS21300 f8b26156e9f470692657bf6400e0e7d8 957 SMART SM00052 692 937 1.2E-121 T 28-03-2018 IPR001633 EAL domain MKLM6_RS21300 f8b26156e9f470692657bf6400e0e7d8 957 SUPERFAMILY SSF158472 300 347 2.88E-10 T 28-03-2018 MKLM6_RS21300 f8b26156e9f470692657bf6400e0e7d8 957 SMART SM00304 297 349 1.4E-13 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS21300 f8b26156e9f470692657bf6400e0e7d8 957 Pfam PF00563 EAL domain 699 932 9.5E-72 T 28-03-2018 IPR001633 EAL domain MKLM6_RS21300 f8b26156e9f470692657bf6400e0e7d8 957 SMART SM00267 506 682 2.4E-63 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS05995 dbba85f407c07cc9257675b995a5366e 673 Gene3D G3DSA:3.30.450.20 105 213 2.1E-4 T 28-03-2018 MKLM6_RS05995 dbba85f407c07cc9257675b995a5366e 673 Gene3D G3DSA:3.30.450.20 433 563 4.9E-9 T 28-03-2018 MKLM6_RS05995 dbba85f407c07cc9257675b995a5366e 673 Gene3D G3DSA:3.30.450.20 214 313 0.096 T 28-03-2018 MKLM6_RS02555 c558e64dc9ca16296ba09948e0f7ecf4 242 Pfam PF13649 Methyltransferase domain 47 142 2.2E-9 T 28-03-2018 MKLM6_RS02555 c558e64dc9ca16296ba09948e0f7ecf4 242 SUPERFAMILY SSF53335 6 198 2.01E-24 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS02555 c558e64dc9ca16296ba09948e0f7ecf4 242 Gene3D G3DSA:3.40.50.150 2 204 1.5E-19 T 28-03-2018 MKLM6_RS02315 d5b8d8fe9c8c4a1ae2e7b68f26bd3141 519 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 8 489 6.9E-135 T 28-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS02315 d5b8d8fe9c8c4a1ae2e7b68f26bd3141 519 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 167 191 1.2E-18 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS02315 d5b8d8fe9c8c4a1ae2e7b68f26bd3141 519 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 385 411 1.2E-18 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS02315 d5b8d8fe9c8c4a1ae2e7b68f26bd3141 519 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 333 352 1.2E-18 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS02315 d5b8d8fe9c8c4a1ae2e7b68f26bd3141 519 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 245 269 1.2E-18 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS02315 d5b8d8fe9c8c4a1ae2e7b68f26bd3141 519 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 136 155 1.2E-18 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS02315 d5b8d8fe9c8c4a1ae2e7b68f26bd3141 519 Pfam PF00361 Proton-conducting membrane transporter 130 428 3.7E-60 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS10320 2438dc275eafe93e70d73343e6d3478b 678 SMART SM00283 383 623 1.7E-55 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS10320 2438dc275eafe93e70d73343e6d3478b 678 Gene3D G3DSA:1.10.287.950 439 609 4.9E-41 T 28-03-2018 MKLM6_RS10320 2438dc275eafe93e70d73343e6d3478b 678 SUPERFAMILY SSF58104 357 628 7.59E-61 T 28-03-2018 MKLM6_RS10320 2438dc275eafe93e70d73343e6d3478b 678 SMART SM00304 337 389 1.7E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS10320 2438dc275eafe93e70d73343e6d3478b 678 ProDom PD936484 POLYPROTEIN GLYCOPROTEIN M G2 TRANSMEMBRANE NONSTRUCTURAL MEMBRANE CONTAINS: PRECURSOR SIGNAL 67 619 0.004 T 28-03-2018 MKLM6_RS10320 2438dc275eafe93e70d73343e6d3478b 678 Pfam PF00672 HAMP domain 350 384 8.7E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS10320 2438dc275eafe93e70d73343e6d3478b 678 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 449 609 2.3E-29 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS10320 2438dc275eafe93e70d73343e6d3478b 678 Gene3D G3DSA:1.10.287.950 46 438 9.5E-12 T 28-03-2018 MKLM6_RS02990 45a530e38f96ce0fa751bbf6b4c73c6f 117 TIGRFAM TIGR00526 folB_dom: FolB domain 1 116 1.3E-33 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MKLM6_RS02990 45a530e38f96ce0fa751bbf6b4c73c6f 117 Pfam PF02152 Dihydroneopterin aldolase 4 112 7.9E-31 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MKLM6_RS02990 45a530e38f96ce0fa751bbf6b4c73c6f 117 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 4 114 8.5E-22 T 28-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MKLM6_RS02990 45a530e38f96ce0fa751bbf6b4c73c6f 117 SMART SM00905 4 114 5.8E-41 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MKLM6_RS02990 45a530e38f96ce0fa751bbf6b4c73c6f 117 SUPERFAMILY SSF55620 1 115 2.22E-34 T 28-03-2018 MKLM6_RS02990 45a530e38f96ce0fa751bbf6b4c73c6f 117 Gene3D G3DSA:3.30.1130.10 1 117 8.2E-33 T 28-03-2018 MKLM6_RS13545 216072abad423f252eccbcf55c4780ff 692 SUPERFAMILY SSF55666 447 546 6.59E-28 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MKLM6_RS13545 216072abad423f252eccbcf55c4780ff 692 SMART SM00316 617 687 1.1E-26 T 28-03-2018 IPR022967 RNA-binding domain, S1 MKLM6_RS13545 216072abad423f252eccbcf55c4780ff 692 Gene3D G3DSA:3.30.230.70 314 541 9.2E-62 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MKLM6_RS13545 216072abad423f252eccbcf55c4780ff 692 PIRSF PIRSF005499 1 692 1.2E-293 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MKLM6_RS13545 216072abad423f252eccbcf55c4780ff 692 Gene3D G3DSA:3.30.1370.10 542 613 2.1E-13 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 MKLM6_RS13545 216072abad423f252eccbcf55c4780ff 692 Pfam PF01138 3' exoribonuclease family, domain 1 13 142 1.1E-20 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MKLM6_RS13545 216072abad423f252eccbcf55c4780ff 692 Pfam PF01138 3' exoribonuclease family, domain 1 321 453 1.8E-22 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MKLM6_RS13545 216072abad423f252eccbcf55c4780ff 692 SMART SM00322 549 614 2.8E-11 T 28-03-2018 IPR004087 K Homology domain GO:0003676 MKLM6_RS13545 216072abad423f252eccbcf55c4780ff 692 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 2 690 30.6 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MKLM6_RS13545 216072abad423f252eccbcf55c4780ff 692 Pfam PF03725 3' exoribonuclease family, domain 2 456 526 1.3E-6 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MKLM6_RS13545 216072abad423f252eccbcf55c4780ff 692 Pfam PF03725 3' exoribonuclease family, domain 2 146 208 6.0E-11 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MKLM6_RS13545 216072abad423f252eccbcf55c4780ff 692 Pfam PF00013 KH domain 554 611 3.6E-9 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 MKLM6_RS13545 216072abad423f252eccbcf55c4780ff 692 SUPERFAMILY SSF54211 289 485 1.77E-49 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS13545 216072abad423f252eccbcf55c4780ff 692 SUPERFAMILY SSF54791 549 626 4.49E-16 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 MKLM6_RS13545 216072abad423f252eccbcf55c4780ff 692 Gene3D G3DSA:3.30.230.70 12 250 3.9E-52 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MKLM6_RS13545 216072abad423f252eccbcf55c4780ff 692 SUPERFAMILY SSF54211 3 142 6.58E-46 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS13545 216072abad423f252eccbcf55c4780ff 692 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 9 689 0.0 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MKLM6_RS13545 216072abad423f252eccbcf55c4780ff 692 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 239 317 7.1E-18 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MKLM6_RS13545 216072abad423f252eccbcf55c4780ff 692 Pfam PF00575 S1 RNA binding domain 616 687 9.5E-20 T 28-03-2018 IPR003029 S1 domain GO:0003676 MKLM6_RS13545 216072abad423f252eccbcf55c4780ff 692 SUPERFAMILY SSF55666 143 234 5.19E-27 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MKLM6_RS13545 216072abad423f252eccbcf55c4780ff 692 Gene3D G3DSA:2.40.50.140 614 692 7.3E-26 T 28-03-2018 MKLM6_RS13545 216072abad423f252eccbcf55c4780ff 692 Gene3D G3DSA:1.10.10.400 251 313 4.6E-21 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MKLM6_RS13545 216072abad423f252eccbcf55c4780ff 692 SUPERFAMILY SSF50249 604 689 1.66E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 Pfam PF00690 Cation transporter/ATPase, N-terminus 9 75 1.5E-16 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 Pfam PF00702 haloacid dehalogenase-like hydrolase 327 647 6.5E-22 T 28-03-2018 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 SUPERFAMILY SSF81653 120 229 7.85E-30 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 492 510 3.8E-13 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 633 649 3.8E-13 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 665 690 3.8E-13 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 605 621 3.8E-13 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 603 723 1.9E-33 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 222 352 1.4E-28 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 88 199 1.8E-19 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 SUPERFAMILY SSF81660 336 536 3.27E-49 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 Pfam PF00689 Cation transporting ATPase, C-terminus 718 889 4.3E-45 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 SUPERFAMILY SSF56784 327 347 1.42E-59 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 SUPERFAMILY SSF56784 489 738 1.42E-59 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 SMART SM00831 8 82 4.7E-27 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 Gene3D G3DSA:3.40.1110.10 293 532 1.6E-43 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 SUPERFAMILY SSF81665 230 323 2.75E-123 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 SUPERFAMILY SSF81665 9 120 2.75E-123 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 SUPERFAMILY SSF81665 683 893 2.75E-123 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 331 337 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 Gene3D G3DSA:1.20.1110.10 654 895 1.2E-65 T 28-03-2018 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 Gene3D G3DSA:2.70.150.10 17 230 7.4E-45 T 28-03-2018 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 Gene3D G3DSA:3.40.50.1000 533 653 2.0E-21 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 532 543 5.2E-40 T 28-03-2018 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 657 669 5.2E-40 T 28-03-2018 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 329 343 5.2E-40 T 28-03-2018 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 167 181 5.2E-40 T 28-03-2018 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 554 564 5.2E-40 T 28-03-2018 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 633 652 5.2E-40 T 28-03-2018 MKLM6_RS03675 ec5f94dd3997302705a7945ec3890846 897 Pfam PF00122 E1-E2 ATPase 121 309 1.2E-54 T 28-03-2018 MKLM6_RS14245 f860aa62bdd3fd4531abdf38c6128af3 240 SUPERFAMILY SSF63380 4 101 2.15E-13 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MKLM6_RS14245 f860aa62bdd3fd4531abdf38c6128af3 240 SUPERFAMILY SSF52343 91 235 1.15E-30 T 28-03-2018 MKLM6_RS14245 f860aa62bdd3fd4531abdf38c6128af3 240 Pfam PF00175 Oxidoreductase NAD-binding domain 112 219 2.6E-17 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MKLM6_RS14245 f860aa62bdd3fd4531abdf38c6128af3 240 Gene3D G3DSA:3.40.50.80 92 234 5.3E-24 T 28-03-2018 MKLM6_RS14245 f860aa62bdd3fd4531abdf38c6128af3 240 Gene3D G3DSA:2.40.30.10 2 91 8.5E-15 T 28-03-2018 MKLM6_RS14245 f860aa62bdd3fd4531abdf38c6128af3 240 PRINTS PR00410 Phenol hydroxylase reductase family signature 111 130 2.1E-10 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MKLM6_RS14245 f860aa62bdd3fd4531abdf38c6128af3 240 PRINTS PR00410 Phenol hydroxylase reductase family signature 31 43 2.1E-10 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MKLM6_RS14245 f860aa62bdd3fd4531abdf38c6128af3 240 PRINTS PR00410 Phenol hydroxylase reductase family signature 205 213 2.1E-10 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MKLM6_RS14245 f860aa62bdd3fd4531abdf38c6128af3 240 PRINTS PR00410 Phenol hydroxylase reductase family signature 95 104 2.1E-10 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MKLM6_RS08810 03b876a8da2d9a2112b0508eac01c3ae 342 Gene3D G3DSA:1.10.10.10 14 76 4.3E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS08810 03b876a8da2d9a2112b0508eac01c3ae 342 Gene3D G3DSA:3.30.930.10 83 292 8.4E-58 T 28-03-2018 MKLM6_RS08810 03b876a8da2d9a2112b0508eac01c3ae 342 Pfam PF02237 Biotin protein ligase C terminal domain 308 340 1.7E-6 T 28-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 MKLM6_RS08810 03b876a8da2d9a2112b0508eac01c3ae 342 Pfam PF08279 HTH domain 19 71 3.4E-10 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 MKLM6_RS08810 03b876a8da2d9a2112b0508eac01c3ae 342 SUPERFAMILY SSF55681 97 291 2.49E-53 T 28-03-2018 MKLM6_RS08810 03b876a8da2d9a2112b0508eac01c3ae 342 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 18 340 32.038 T 28-03-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 MKLM6_RS08810 03b876a8da2d9a2112b0508eac01c3ae 342 SUPERFAMILY SSF46785 16 73 7.14E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS08810 03b876a8da2d9a2112b0508eac01c3ae 342 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 99 340 3.7E-52 T 28-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 MKLM6_RS08810 03b876a8da2d9a2112b0508eac01c3ae 342 Gene3D G3DSA:2.30.30.100 294 340 7.4E-11 T 28-03-2018 MKLM6_RS08810 03b876a8da2d9a2112b0508eac01c3ae 342 SUPERFAMILY SSF50037 297 340 1.01E-6 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal MKLM6_RS08810 03b876a8da2d9a2112b0508eac01c3ae 342 Pfam PF03099 Biotin/lipoate A/B protein ligase family 104 227 9.6E-17 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 MKLM6_RS07925 f7b355a7cfb9c8c0a90fa18f91a3c572 322 SUPERFAMILY SSF49464 29 79 1.51E-7 T 28-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain MKLM6_RS07925 f7b355a7cfb9c8c0a90fa18f91a3c572 322 Gene3D G3DSA:2.60.40.1120 28 149 1.3E-7 T 28-03-2018 MKLM6_RS03700 88d268812570117385fcf4aed81a7fd7 257 Pfam PF01627 Hpt domain 154 226 1.4E-5 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS03700 88d268812570117385fcf4aed81a7fd7 257 Pfam PF00072 Response regulator receiver domain 8 120 6.3E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS03700 88d268812570117385fcf4aed81a7fd7 257 Gene3D G3DSA:1.20.120.160 144 242 1.9E-8 T 28-03-2018 MKLM6_RS03700 88d268812570117385fcf4aed81a7fd7 257 SUPERFAMILY SSF52172 5 124 4.84E-37 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS03700 88d268812570117385fcf4aed81a7fd7 257 Gene3D G3DSA:3.40.50.2300 1 143 1.2E-35 T 28-03-2018 MKLM6_RS03700 88d268812570117385fcf4aed81a7fd7 257 SMART SM00448 6 120 1.9E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS03700 88d268812570117385fcf4aed81a7fd7 257 SUPERFAMILY SSF47226 103 226 3.66E-13 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS01120 75b52aa366010051364a7cd94623c545 181 Gene3D G3DSA:3.40.50.300 3 181 4.0E-32 T 28-03-2018 MKLM6_RS01120 75b52aa366010051364a7cd94623c545 181 Pfam PF01202 Shikimate kinase 13 169 9.5E-52 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MKLM6_RS01120 75b52aa366010051364a7cd94623c545 181 ProSitePatterns PS01128 Shikimate kinase signature. 60 85 - T 28-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MKLM6_RS01120 75b52aa366010051364a7cd94623c545 181 SUPERFAMILY SSF52540 5 167 2.44E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS01120 75b52aa366010051364a7cd94623c545 181 PRINTS PR01100 Shikimate kinase family signature 7 22 2.1E-24 T 28-03-2018 MKLM6_RS01120 75b52aa366010051364a7cd94623c545 181 PRINTS PR01100 Shikimate kinase family signature 98 115 2.1E-24 T 28-03-2018 MKLM6_RS01120 75b52aa366010051364a7cd94623c545 181 PRINTS PR01100 Shikimate kinase family signature 31 44 2.1E-24 T 28-03-2018 MKLM6_RS01120 75b52aa366010051364a7cd94623c545 181 PRINTS PR01100 Shikimate kinase family signature 77 86 2.1E-24 T 28-03-2018 MKLM6_RS01120 75b52aa366010051364a7cd94623c545 181 PRINTS PR01100 Shikimate kinase family signature 59 67 2.1E-24 T 28-03-2018 MKLM6_RS01120 75b52aa366010051364a7cd94623c545 181 Hamap MF_00109 Shikimate kinase [aroK]. 4 170 28.999 T 28-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MKLM6_RS18300 77bd9b251091041fee04b871ae8058da 350 PIRSF PIRSF000149 1 348 2.0E-66 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS18300 77bd9b251091041fee04b871ae8058da 350 Gene3D G3DSA:3.40.50.720 1 170 1.7E-38 T 28-03-2018 MKLM6_RS18300 77bd9b251091041fee04b871ae8058da 350 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 4 109 8.9E-14 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS18300 77bd9b251091041fee04b871ae8058da 350 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 156 174 1.6E-10 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS18300 77bd9b251091041fee04b871ae8058da 350 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 183 199 1.6E-10 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS18300 77bd9b251091041fee04b871ae8058da 350 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 239 256 1.6E-10 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS18300 77bd9b251091041fee04b871ae8058da 350 SUPERFAMILY SSF55347 162 318 1.8E-35 T 28-03-2018 MKLM6_RS18300 77bd9b251091041fee04b871ae8058da 350 SMART SM00846 3 162 5.3E-17 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS18300 77bd9b251091041fee04b871ae8058da 350 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 168 321 9.6E-31 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS18300 77bd9b251091041fee04b871ae8058da 350 Gene3D G3DSA:3.30.360.10 171 329 5.3E-34 T 28-03-2018 MKLM6_RS18300 77bd9b251091041fee04b871ae8058da 350 SUPERFAMILY SSF51735 3 180 9.05E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 Gene3D G3DSA:1.25.40.10 954 1014 3.8E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 Pfam PF13432 Tetratricopeptide repeat 823 881 0.0041 T 28-03-2018 MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 Pfam PF13432 Tetratricopeptide repeat 894 955 8.1E-6 T 28-03-2018 MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 Gene3D G3DSA:3.40.50.150 79 261 4.3E-28 T 28-03-2018 MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 Gene3D G3DSA:3.40.50.150 520 721 8.4E-20 T 28-03-2018 MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 SUPERFAMILY SSF53335 533 711 1.04E-22 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 SUPERFAMILY SSF53335 55 247 2.54E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 Pfam PF05050 Methyltransferase FkbM domain 89 242 2.7E-11 T 28-03-2018 IPR006342 Methyltransferase FkbM MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 Pfam PF05050 Methyltransferase FkbM domain 554 705 3.0E-15 T 28-03-2018 IPR006342 Methyltransferase FkbM MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 Gene3D G3DSA:1.10.287.1110 941 953 0.001 T 28-03-2018 MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 Gene3D G3DSA:1.25.40.10 789 901 6.7E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 SUPERFAMILY SSF48452 823 989 3.8E-31 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 Gene3D G3DSA:3.40.50.2000 1224 1410 1.6E-25 T 28-03-2018 MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 SMART SM00028 888 921 6.4E-5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 SMART SM00028 956 989 0.032 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 SMART SM00028 922 955 0.0097 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 SMART SM00028 852 885 160.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 SMART SM00028 818 851 120.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 Pfam PF13176 Tetratricopeptide repeat 958 984 0.003 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 534 672 1.3E-14 T 28-03-2018 IPR006342 Methyltransferase FkbM MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 88 224 8.6E-21 T 28-03-2018 IPR006342 Methyltransferase FkbM MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 Gene3D G3DSA:1.25.40.10 902 940 5.7E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 Pfam PF13844 Glycosyl transferase family 41 1072 1222 1.1E-37 T 28-03-2018 IPR029489 O-GlcNAc transferase, C-terminal Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 MKLM6_RS18105 f25390ac3c097024d5cf1c7ee8baafab 1434 Pfam PF13844 Glycosyl transferase family 41 1233 1423 3.4E-52 T 28-03-2018 IPR029489 O-GlcNAc transferase, C-terminal Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 MKLM6_RS02845 a44ec65233e2d97dca9621679ae4f349 582 SUPERFAMILY SSF90123 8 320 3.79E-73 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MKLM6_RS02845 a44ec65233e2d97dca9621679ae4f349 582 Pfam PF00664 ABC transporter transmembrane region 23 280 1.8E-42 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MKLM6_RS02845 a44ec65233e2d97dca9621679ae4f349 582 SMART SM00382 359 546 8.9E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS02845 a44ec65233e2d97dca9621679ae4f349 582 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS02845 a44ec65233e2d97dca9621679ae4f349 582 Gene3D G3DSA:3.40.50.300 330 567 1.0E-75 T 28-03-2018 MKLM6_RS02845 a44ec65233e2d97dca9621679ae4f349 582 SUPERFAMILY SSF52540 323 571 3.48E-94 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS02845 a44ec65233e2d97dca9621679ae4f349 582 Gene3D G3DSA:1.20.1560.10 1 323 2.2E-66 T 28-03-2018 MKLM6_RS02845 a44ec65233e2d97dca9621679ae4f349 582 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 7 573 9.5E-224 T 28-03-2018 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 MKLM6_RS02845 a44ec65233e2d97dca9621679ae4f349 582 Pfam PF00005 ABC transporter 352 500 8.4E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS09020 6e11c2ba28bad07eace993e8442d7a0f 264 SUPERFAMILY SSF52172 38 162 2.42E-38 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS09020 6e11c2ba28bad07eace993e8442d7a0f 264 Pfam PF00072 Response regulator receiver domain 43 151 5.3E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS09020 6e11c2ba28bad07eace993e8442d7a0f 264 SMART SM00862 186 261 2.6E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS09020 6e11c2ba28bad07eace993e8442d7a0f 264 Gene3D G3DSA:3.40.50.2300 31 163 3.4E-33 T 28-03-2018 MKLM6_RS09020 6e11c2ba28bad07eace993e8442d7a0f 264 Pfam PF00486 Transcriptional regulatory protein, C terminal 188 261 1.2E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS09020 6e11c2ba28bad07eace993e8442d7a0f 264 Gene3D G3DSA:1.10.10.10 164 264 2.6E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS09020 6e11c2ba28bad07eace993e8442d7a0f 264 SUPERFAMILY SSF46894 171 262 1.28E-25 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MKLM6_RS09020 6e11c2ba28bad07eace993e8442d7a0f 264 SMART SM00448 41 151 1.6E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS09690 c21e4bdaa385b98de7041d45d54694f2 740 Pfam PF00990 Diguanylate cyclase, GGDEF domain 312 469 6.1E-54 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS09690 c21e4bdaa385b98de7041d45d54694f2 740 SUPERFAMILY SSF55073 317 475 6.28E-53 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS09690 c21e4bdaa385b98de7041d45d54694f2 740 Pfam PF13426 PAS domain 196 300 1.3E-13 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09690 c21e4bdaa385b98de7041d45d54694f2 740 Pfam PF08448 PAS fold 78 179 3.8E-6 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS09690 c21e4bdaa385b98de7041d45d54694f2 740 Gene3D G3DSA:3.30.70.270 314 481 4.8E-63 T 28-03-2018 MKLM6_RS09690 c21e4bdaa385b98de7041d45d54694f2 740 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 65 184 4.0E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09690 c21e4bdaa385b98de7041d45d54694f2 740 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 197 306 2.4E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09690 c21e4bdaa385b98de7041d45d54694f2 740 SMART SM00052 483 730 1.1E-100 T 28-03-2018 IPR001633 EAL domain MKLM6_RS09690 c21e4bdaa385b98de7041d45d54694f2 740 SMART SM00091 68 134 0.013 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09690 c21e4bdaa385b98de7041d45d54694f2 740 SMART SM00091 185 253 0.0013 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09690 c21e4bdaa385b98de7041d45d54694f2 740 SUPERFAMILY SSF55785 68 155 2.09E-11 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09690 c21e4bdaa385b98de7041d45d54694f2 740 SMART SM00267 301 473 2.2E-67 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS09690 c21e4bdaa385b98de7041d45d54694f2 740 Pfam PF00563 EAL domain 489 725 2.0E-70 T 28-03-2018 IPR001633 EAL domain MKLM6_RS09690 c21e4bdaa385b98de7041d45d54694f2 740 Gene3D G3DSA:3.30.450.20 49 188 3.0E-17 T 28-03-2018 MKLM6_RS09690 c21e4bdaa385b98de7041d45d54694f2 740 Gene3D G3DSA:3.30.450.20 189 313 1.3E-24 T 28-03-2018 MKLM6_RS09690 c21e4bdaa385b98de7041d45d54694f2 740 SUPERFAMILY SSF55785 201 309 2.9E-25 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09690 c21e4bdaa385b98de7041d45d54694f2 740 SUPERFAMILY SSF141868 489 737 8.76E-85 T 28-03-2018 IPR001633 EAL domain MKLM6_RS09690 c21e4bdaa385b98de7041d45d54694f2 740 Gene3D G3DSA:3.20.20.450 482 740 5.7E-95 T 28-03-2018 IPR001633 EAL domain MKLM6_RS09690 c21e4bdaa385b98de7041d45d54694f2 740 SMART SM00086 259 301 9.8E-6 T 28-03-2018 IPR001610 PAC motif MKLM6_RS09690 c21e4bdaa385b98de7041d45d54694f2 740 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 308 471 1.1E-47 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS12125 a37a9387a4b6bcaae944d865046388a8 446 Gene3D G3DSA:1.10.1140.10 341 446 5.2E-28 T 28-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MKLM6_RS12125 a37a9387a4b6bcaae944d865046388a8 446 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 327 336 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MKLM6_RS12125 a37a9387a4b6bcaae944d865046388a8 446 SMART SM00382 135 375 0.0038 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS12125 a37a9387a4b6bcaae944d865046388a8 446 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 4 443 5.2E-172 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 MKLM6_RS12125 a37a9387a4b6bcaae944d865046388a8 446 Gene3D G3DSA:2.40.10.170 1 52 2.4E-13 T 28-03-2018 MKLM6_RS12125 a37a9387a4b6bcaae944d865046388a8 446 SUPERFAMILY SSF50615 3 66 4.45E-12 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MKLM6_RS12125 a37a9387a4b6bcaae944d865046388a8 446 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 4 66 1.0E-6 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MKLM6_RS12125 a37a9387a4b6bcaae944d865046388a8 446 SUPERFAMILY SSF47917 339 444 2.88E-36 T 28-03-2018 MKLM6_RS12125 a37a9387a4b6bcaae944d865046388a8 446 SUPERFAMILY SSF52540 70 342 3.68E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS12125 a37a9387a4b6bcaae944d865046388a8 446 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 123 336 3.4E-63 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MKLM6_RS12125 a37a9387a4b6bcaae944d865046388a8 446 Gene3D G3DSA:3.40.50.300 53 336 1.4E-79 T 28-03-2018 MKLM6_RS10185 d8fdda3db569f68973840d25fd06bc99 636 SMART SM00487 19 282 2.0E-6 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MKLM6_RS10185 d8fdda3db569f68973840d25fd06bc99 636 Pfam PF13307 Helicase C-terminal domain 463 619 8.4E-35 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 MKLM6_RS10185 d8fdda3db569f68973840d25fd06bc99 636 Gene3D G3DSA:3.40.50.300 449 631 2.5E-9 T 28-03-2018 MKLM6_RS10185 d8fdda3db569f68973840d25fd06bc99 636 Pfam PF06733 DEAD_2 183 251 4.8E-6 T 28-03-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 MKLM6_RS10185 d8fdda3db569f68973840d25fd06bc99 636 SUPERFAMILY SSF52540 20 112 3.43E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS10185 d8fdda3db569f68973840d25fd06bc99 636 SUPERFAMILY SSF52540 189 246 3.43E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS10185 d8fdda3db569f68973840d25fd06bc99 636 SUPERFAMILY SSF52540 566 603 3.43E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS10185 d8fdda3db569f68973840d25fd06bc99 636 SUPERFAMILY SSF52540 577 593 1.0E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS10185 d8fdda3db569f68973840d25fd06bc99 636 SUPERFAMILY SSF52540 190 232 1.0E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS10185 d8fdda3db569f68973840d25fd06bc99 636 SUPERFAMILY SSF52540 392 546 1.0E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS10185 d8fdda3db569f68973840d25fd06bc99 636 SMART SM00491 478 607 2.1E-41 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 MKLM6_RS10185 d8fdda3db569f68973840d25fd06bc99 636 SMART SM00488 21 273 0.0051 T 28-03-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 MKLM6_RS10185 d8fdda3db569f68973840d25fd06bc99 636 Pfam PF00270 DEAD/DEAH box helicase 34 85 1.2E-5 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MKLM6_RS10185 d8fdda3db569f68973840d25fd06bc99 636 Gene3D G3DSA:3.40.50.300 22 417 2.2E-30 T 28-03-2018 MKLM6_RS06460 ddf99b48d6a41c573f25a50e46031814 353 PIRSF PIRSF018266 7 350 2.7E-68 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component MKLM6_RS06460 ddf99b48d6a41c573f25a50e46031814 353 Pfam PF16220 Domain of unknown function (DUF4880) 14 56 9.5E-6 T 28-03-2018 IPR032623 FecR, N-terminal MKLM6_RS06460 ddf99b48d6a41c573f25a50e46031814 353 Pfam PF16344 Domain of unknown function (DUF4974) 261 338 2.0E-10 T 28-03-2018 IPR032508 Protein FecR, C-terminal MKLM6_RS06460 ddf99b48d6a41c573f25a50e46031814 353 Pfam PF04773 FecR protein 115 207 8.2E-21 T 28-03-2018 IPR006860 FecR protein MKLM6_RS03900 feecb23f84e7bffa60b9a56ce3e2c574 427 Gene3D G3DSA:3.40.50.10070 24 162 2.0E-32 T 28-03-2018 MKLM6_RS03900 feecb23f84e7bffa60b9a56ce3e2c574 427 Gene3D G3DSA:2.140.10.30 336 427 5.0E-12 T 28-03-2018 MKLM6_RS03900 feecb23f84e7bffa60b9a56ce3e2c574 427 SUPERFAMILY SSF52964 30 159 2.88E-34 T 28-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 MKLM6_RS03900 feecb23f84e7bffa60b9a56ce3e2c574 427 Gene3D G3DSA:2.60.120.20 164 234 1.8E-10 T 28-03-2018 MKLM6_RS03900 feecb23f84e7bffa60b9a56ce3e2c574 427 Gene3D G3DSA:2.60.120.20 280 330 6.8E-14 T 28-03-2018 MKLM6_RS03900 feecb23f84e7bffa60b9a56ce3e2c574 427 Gene3D G3DSA:2.60.120.20 235 279 6.6E-7 T 28-03-2018 MKLM6_RS03900 feecb23f84e7bffa60b9a56ce3e2c574 427 Hamap MF_00671 Protein TolB [tolB]. 6 425 34.527 T 28-03-2018 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 MKLM6_RS03900 feecb23f84e7bffa60b9a56ce3e2c574 427 Pfam PF07676 WD40-like Beta Propeller Repeat 279 314 1.3E-12 T 28-03-2018 IPR011659 WD40-like Beta Propeller MKLM6_RS03900 feecb23f84e7bffa60b9a56ce3e2c574 427 Pfam PF07676 WD40-like Beta Propeller Repeat 196 227 1.5E-8 T 28-03-2018 IPR011659 WD40-like Beta Propeller MKLM6_RS03900 feecb23f84e7bffa60b9a56ce3e2c574 427 Pfam PF07676 WD40-like Beta Propeller Repeat 238 271 9.7E-10 T 28-03-2018 IPR011659 WD40-like Beta Propeller MKLM6_RS03900 feecb23f84e7bffa60b9a56ce3e2c574 427 Pfam PF07676 WD40-like Beta Propeller Repeat 375 398 3.6E-4 T 28-03-2018 IPR011659 WD40-like Beta Propeller MKLM6_RS03900 feecb23f84e7bffa60b9a56ce3e2c574 427 Pfam PF04052 TolB amino-terminal domain 25 126 2.4E-25 T 28-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 MKLM6_RS03900 feecb23f84e7bffa60b9a56ce3e2c574 427 SUPERFAMILY SSF69304 152 427 3.79E-56 T 28-03-2018 MKLM6_RS03900 feecb23f84e7bffa60b9a56ce3e2c574 427 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 18 425 1.7E-157 T 28-03-2018 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 MKLM6_RS08255 89cb50014ca1cf240eca9e9b36e3e72c 1173 SMART SM00490 697 783 1.0E-17 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS08255 89cb50014ca1cf240eca9e9b36e3e72c 1173 Pfam PF00271 Helicase conserved C-terminal domain 668 783 1.0E-16 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS08255 89cb50014ca1cf240eca9e9b36e3e72c 1173 Gene3D G3DSA:3.40.50.10810 185 494 9.2E-25 T 28-03-2018 MKLM6_RS08255 89cb50014ca1cf240eca9e9b36e3e72c 1173 SUPERFAMILY SSF52540 389 449 3.19E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS08255 89cb50014ca1cf240eca9e9b36e3e72c 1173 SUPERFAMILY SSF52540 657 831 3.19E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS08255 89cb50014ca1cf240eca9e9b36e3e72c 1173 SMART SM00487 249 455 8.6E-7 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MKLM6_RS08255 89cb50014ca1cf240eca9e9b36e3e72c 1173 Pfam PF00176 SNF2 family N-terminal domain 273 571 3.9E-14 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 MKLM6_RS08255 89cb50014ca1cf240eca9e9b36e3e72c 1173 Gene3D G3DSA:3.40.50.300 651 1138 8.5E-30 T 28-03-2018 MKLM6_RS08255 89cb50014ca1cf240eca9e9b36e3e72c 1173 SUPERFAMILY SSF52540 238 456 4.47E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS16040 3e1f2dea1f0d5a5da572eb4b85ea8d4b 110 Pfam PF01740 STAS domain 3 104 6.4E-16 T 28-03-2018 IPR002645 STAS domain MKLM6_RS16040 3e1f2dea1f0d5a5da572eb4b85ea8d4b 110 Gene3D G3DSA:3.30.750.24 1 108 3.2E-19 T 28-03-2018 IPR002645 STAS domain MKLM6_RS16040 3e1f2dea1f0d5a5da572eb4b85ea8d4b 110 SUPERFAMILY SSF52091 1 106 3.14E-24 T 28-03-2018 IPR002645 STAS domain MKLM6_RS16040 3e1f2dea1f0d5a5da572eb4b85ea8d4b 110 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 103 9.1E-23 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 MKLM6_RS05520 8ae819463442561380d1caaa5460ad80 299 SUPERFAMILY SSF53850 90 294 1.38E-43 T 28-03-2018 MKLM6_RS05520 8ae819463442561380d1caaa5460ad80 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 6.6E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS05520 8ae819463442561380d1caaa5460ad80 299 Gene3D G3DSA:3.40.190.10 180 266 3.7E-20 T 28-03-2018 MKLM6_RS05520 8ae819463442561380d1caaa5460ad80 299 Gene3D G3DSA:3.40.190.10 93 179 3.1E-17 T 28-03-2018 MKLM6_RS05520 8ae819463442561380d1caaa5460ad80 299 SUPERFAMILY SSF46785 3 113 3.06E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS05520 8ae819463442561380d1caaa5460ad80 299 Pfam PF03466 LysR substrate binding domain 89 294 6.5E-41 T 28-03-2018 IPR005119 LysR, substrate-binding MKLM6_RS05520 8ae819463442561380d1caaa5460ad80 299 Gene3D G3DSA:1.10.10.10 1 83 3.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS02630 32d1a8cdc6fdaa264beb407d7077b1bd 426 Gene3D G3DSA:1.10.3210.10 144 412 2.4E-32 T 28-03-2018 MKLM6_RS02630 32d1a8cdc6fdaa264beb407d7077b1bd 426 SUPERFAMILY SSF109604 163 419 6.51E-45 T 28-03-2018 MKLM6_RS02630 32d1a8cdc6fdaa264beb407d7077b1bd 426 Gene3D G3DSA:2.60.120.10 24 129 3.9E-9 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS02630 32d1a8cdc6fdaa264beb407d7077b1bd 426 SUPERFAMILY SSF51206 25 128 3.67E-12 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like MKLM6_RS02630 32d1a8cdc6fdaa264beb407d7077b1bd 426 Pfam PF08668 HDOD domain 167 348 4.7E-35 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD MKLM6_RS05875 cd82c2d8d81d1fee2a55debc2ac13062 226 SUPERFAMILY SSF46894 126 225 9.64E-31 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MKLM6_RS05875 cd82c2d8d81d1fee2a55debc2ac13062 226 SUPERFAMILY SSF52172 1 123 1.29E-39 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS05875 cd82c2d8d81d1fee2a55debc2ac13062 226 Gene3D G3DSA:3.40.50.2300 1 123 7.6E-36 T 28-03-2018 MKLM6_RS05875 cd82c2d8d81d1fee2a55debc2ac13062 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 223 9.2E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS05875 cd82c2d8d81d1fee2a55debc2ac13062 226 SMART SM00862 148 223 5.9E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS05875 cd82c2d8d81d1fee2a55debc2ac13062 226 Pfam PF00072 Response regulator receiver domain 3 113 5.1E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS05875 cd82c2d8d81d1fee2a55debc2ac13062 226 SMART SM00448 1 112 1.3E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS05875 cd82c2d8d81d1fee2a55debc2ac13062 226 Gene3D G3DSA:1.10.10.10 124 226 9.8E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS18840 3a01494c8e07934dd5b4b45ca12dbd40 470 PIRSF PIRSF500217 1 470 5.6E-143 T 28-03-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 MKLM6_RS18840 3a01494c8e07934dd5b4b45ca12dbd40 470 PIRSF PIRSF016636 1 470 1.9E-140 T 28-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB MKLM6_RS18840 3a01494c8e07934dd5b4b45ca12dbd40 470 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 145 350 4.4E-22 T 28-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT MKLM6_RS20145 4d1679ecc375ed2a61404ac403f0b9fe 168 Hamap MF_00286 Disulfide bond formation protein B [dsbB]. 4 164 21.496 T 28-03-2018 IPR022920 Disulphide bond formation protein DsbB MKLM6_RS20145 4d1679ecc375ed2a61404ac403f0b9fe 168 Pfam PF02600 Disulfide bond formation protein DsbB 9 155 3.5E-40 T 28-03-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 MKLM6_RS20145 4d1679ecc375ed2a61404ac403f0b9fe 168 SUPERFAMILY SSF158442 12 157 1.05E-36 T 28-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain MKLM6_RS20145 4d1679ecc375ed2a61404ac403f0b9fe 168 Gene3D G3DSA:1.20.1550.10 4 165 5.0E-43 T 28-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain MKLM6_RS16900 168a8309c1f798eef7df64be8098f752 578 SUPERFAMILY SSF52518 371 567 3.32E-70 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS16900 168a8309c1f798eef7df64be8098f752 578 Gene3D G3DSA:3.40.50.970 351 563 2.9E-52 T 28-03-2018 MKLM6_RS16900 168a8309c1f798eef7df64be8098f752 578 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 393 541 3.3E-50 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MKLM6_RS16900 168a8309c1f798eef7df64be8098f752 578 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 170 1.5E-58 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MKLM6_RS16900 168a8309c1f798eef7df64be8098f752 578 Gene3D G3DSA:3.40.50.1220 192 350 9.2E-51 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MKLM6_RS16900 168a8309c1f798eef7df64be8098f752 578 SUPERFAMILY SSF52518 3 179 6.48E-66 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS16900 168a8309c1f798eef7df64be8098f752 578 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 3 563 2.9E-262 T 28-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MKLM6_RS16900 168a8309c1f798eef7df64be8098f752 578 Gene3D G3DSA:3.40.50.970 1 191 2.7E-64 T 28-03-2018 MKLM6_RS16900 168a8309c1f798eef7df64be8098f752 578 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 195 329 1.6E-44 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MKLM6_RS16900 168a8309c1f798eef7df64be8098f752 578 SUPERFAMILY SSF52467 188 361 1.69E-64 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MKLM6_RS18035 6e7ca3d8e6bd4f96ce6128dd21ceefc9 362 TIGRFAM TIGR03569 NeuB_NnaB: N-acetylneuraminate synthase 4 354 9.6E-145 T 28-03-2018 IPR020007 N-acetylneuraminate synthase KEGG: 00520+2.5.1.101|KEGG: 00900+2.5.1.10|MetaCyc: PWY-5123|MetaCyc: PWY-6749|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7131|MetaCyc: PWY-7721|MetaCyc: PWY-7736 MKLM6_RS18035 6e7ca3d8e6bd4f96ce6128dd21ceefc9 362 Pfam PF03102 NeuB family 24 286 5.1E-98 T 28-03-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 MKLM6_RS18035 6e7ca3d8e6bd4f96ce6128dd21ceefc9 362 Gene3D G3DSA:3.90.1210.10 293 358 4.5E-17 T 28-03-2018 MKLM6_RS18035 6e7ca3d8e6bd4f96ce6128dd21ceefc9 362 Gene3D G3DSA:3.20.20.70 1 288 8.9E-89 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS18035 6e7ca3d8e6bd4f96ce6128dd21ceefc9 362 SUPERFAMILY SSF51269 295 355 2.67E-16 T 28-03-2018 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal Reactome: R-HSA-4085001 MKLM6_RS18035 6e7ca3d8e6bd4f96ce6128dd21ceefc9 362 SUPERFAMILY SSF51569 3 312 7.33E-80 T 28-03-2018 MKLM6_RS18065 63a9b9bf80e6985d7a3c006d5f0f21d5 326 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 306 5.9E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS18065 63a9b9bf80e6985d7a3c006d5f0f21d5 326 Gene3D G3DSA:3.40.50.720 2 175 2.9E-40 T 28-03-2018 MKLM6_RS18065 63a9b9bf80e6985d7a3c006d5f0f21d5 326 TIGRFAM TIGR04180 EDH_00030: NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family 4 296 8.4E-160 T 28-03-2018 IPR026390 NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family MKLM6_RS18065 63a9b9bf80e6985d7a3c006d5f0f21d5 326 Gene3D G3DSA:3.90.25.10 176 322 7.1E-37 T 28-03-2018 MKLM6_RS18065 63a9b9bf80e6985d7a3c006d5f0f21d5 326 SUPERFAMILY SSF51735 1 320 5.65E-95 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS06465 6a1b1cb35c7693bfe9e10f73e47bcfea 797 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 153 796 5.5E-115 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 MKLM6_RS06465 6a1b1cb35c7693bfe9e10f73e47bcfea 797 Gene3D G3DSA:2.170.130.10 105 259 1.6E-22 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS06465 6a1b1cb35c7693bfe9e10f73e47bcfea 797 Pfam PF00593 TonB dependent receptor 323 795 4.9E-58 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS06465 6a1b1cb35c7693bfe9e10f73e47bcfea 797 SUPERFAMILY SSF56935 109 797 1.59E-133 T 28-03-2018 MKLM6_RS06465 6a1b1cb35c7693bfe9e10f73e47bcfea 797 Pfam PF07660 Secretin and TonB N terminus short domain 55 101 9.0E-8 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MKLM6_RS06465 6a1b1cb35c7693bfe9e10f73e47bcfea 797 Gene3D G3DSA:2.40.170.20 260 797 2.4E-92 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS06465 6a1b1cb35c7693bfe9e10f73e47bcfea 797 Pfam PF07715 TonB-dependent Receptor Plug Domain 151 246 5.9E-15 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS06465 6a1b1cb35c7693bfe9e10f73e47bcfea 797 SMART SM00965 53 104 2.1E-11 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MKLM6_RS01930 7784f76558fead566676f4331913a4db 175 SUPERFAMILY SSF52540 2 173 7.97E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS01930 7784f76558fead566676f4331913a4db 175 PIRSF PIRSF006135 1 175 4.3E-55 T 28-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MKLM6_RS01930 7784f76558fead566676f4331913a4db 175 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 4 170 5.2E-61 T 28-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MKLM6_RS01930 7784f76558fead566676f4331913a4db 175 Gene3D G3DSA:3.40.50.300 2 173 4.3E-63 T 28-03-2018 MKLM6_RS14095 39f50d732b4b4331c8ad91bda5dc3d21 406 Gene3D G3DSA:3.30.70.270 116 291 2.4E-32 T 28-03-2018 MKLM6_RS14095 39f50d732b4b4331c8ad91bda5dc3d21 406 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 144 162 1.1E-5 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MKLM6_RS14095 39f50d732b4b4331c8ad91bda5dc3d21 406 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 220 233 1.1E-5 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MKLM6_RS14095 39f50d732b4b4331c8ad91bda5dc3d21 406 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 76 89 1.1E-5 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MKLM6_RS14095 39f50d732b4b4331c8ad91bda5dc3d21 406 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 202 215 1.1E-5 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MKLM6_RS14095 39f50d732b4b4331c8ad91bda5dc3d21 406 SUPERFAMILY SSF56672 31 360 1.38E-47 T 28-03-2018 MKLM6_RS14095 39f50d732b4b4331c8ad91bda5dc3d21 406 Pfam PF08388 Group II intron, maturase-specific domain 304 374 5.8E-16 T 28-03-2018 IPR013597 Group II intron, maturase-specific MKLM6_RS14095 39f50d732b4b4331c8ad91bda5dc3d21 406 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 81 291 5.8E-42 T 28-03-2018 IPR000477 Reverse transcriptase domain MKLM6_RS14095 39f50d732b4b4331c8ad91bda5dc3d21 406 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 26 366 3.8E-119 T 28-03-2018 IPR030931 Group II intron reverse transcriptase/maturase MKLM6_RS02720 f886948361af2a1db1452d30ea7e5c09 137 TIGRFAM TIGR03500 FliO_TIGR: flagellar biosynthetic protein FliO 35 102 4.2E-17 T 28-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 MKLM6_RS02720 f886948361af2a1db1452d30ea7e5c09 137 Pfam PF04347 Flagellar biosynthesis protein, FliO 47 129 4.6E-14 T 28-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 MKLM6_RS03155 834bc730de16f8fadf610977373654a7 375 Pfam PF07687 Peptidase dimerisation domain 175 282 1.0E-22 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain MKLM6_RS03155 834bc730de16f8fadf610977373654a7 375 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 2 375 51.056 T 28-03-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 MKLM6_RS03155 834bc730de16f8fadf610977373654a7 375 SUPERFAMILY SSF53187 292 374 2.88E-64 T 28-03-2018 MKLM6_RS03155 834bc730de16f8fadf610977373654a7 375 SUPERFAMILY SSF53187 3 178 2.88E-64 T 28-03-2018 MKLM6_RS03155 834bc730de16f8fadf610977373654a7 375 Gene3D G3DSA:3.40.630.10 1 280 4.7E-60 T 28-03-2018 MKLM6_RS03155 834bc730de16f8fadf610977373654a7 375 Pfam PF01546 Peptidase family M20/M25/M40 63 371 1.7E-43 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 MKLM6_RS03155 834bc730de16f8fadf610977373654a7 375 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 97 135 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MKLM6_RS03155 834bc730de16f8fadf610977373654a7 375 Gene3D G3DSA:3.40.630.10 293 373 2.9E-5 T 28-03-2018 MKLM6_RS03155 834bc730de16f8fadf610977373654a7 375 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 5 373 6.5E-165 T 28-03-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 MKLM6_RS03155 834bc730de16f8fadf610977373654a7 375 SUPERFAMILY SSF55031 179 288 2.24E-27 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain MKLM6_RS17460 99a834ac7f8d23b3fc64e59f74d46493 307 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 96 266 4.3E-14 T 28-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 MKLM6_RS17460 99a834ac7f8d23b3fc64e59f74d46493 307 Gene3D G3DSA:3.40.50.150 91 292 1.0E-28 T 28-03-2018 MKLM6_RS17460 99a834ac7f8d23b3fc64e59f74d46493 307 Gene3D G3DSA:2.60.40.1180 37 90 6.6E-15 T 28-03-2018 MKLM6_RS17460 99a834ac7f8d23b3fc64e59f74d46493 307 SUPERFAMILY SSF53335 33 271 1.05E-48 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS11160 c2e6144f51c1141e5fa5397026f268a1 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 194 213 7.2E-6 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MKLM6_RS11160 c2e6144f51c1141e5fa5397026f268a1 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 56 78 7.2E-6 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MKLM6_RS11160 c2e6144f51c1141e5fa5397026f268a1 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 174 193 7.2E-6 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MKLM6_RS11160 c2e6144f51c1141e5fa5397026f268a1 254 PIRSF PIRSF006648 2 251 6.1E-25 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MKLM6_RS11160 c2e6144f51c1141e5fa5397026f268a1 254 Pfam PF01061 ABC-2 type transporter 7 216 3.3E-31 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MKLM6_RS00475 ed702242559cd537cd7b391d9e5392a4 134 ProDom PD080812 PLASMID Y4OB BMEII097 AGR_L_107P MLL2216 BMEII0977 ATU4831 20 129 7.0E-35 T 28-03-2018 IPR020358 Uncharacterised protein family Y4oB MKLM6_RS00475 ed702242559cd537cd7b391d9e5392a4 134 Pfam PF09722 Protein of unknown function (DUF2384) 80 129 1.5E-7 T 28-03-2018 IPR024467 Domain of unknown function DUF2384 MKLM6_RS08250 fe3a98bbbb851835422dae0137fd5717 68 Pfam PF02416 mttA/Hcf106 family 4 48 3.3E-14 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 MKLM6_RS08250 fe3a98bbbb851835422dae0137fd5717 68 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 2 47 7.2E-20 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 MKLM6_RS08250 fe3a98bbbb851835422dae0137fd5717 68 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 67 19.415 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 MKLM6_RS07655 3dceeb90f46016e8f962a304a8ade989 204 Gene3D G3DSA:3.40.50.150 8 199 6.9E-16 T 28-03-2018 MKLM6_RS07655 3dceeb90f46016e8f962a304a8ade989 204 Pfam PF06080 Protein of unknown function (DUF938) 5 197 1.6E-64 T 28-03-2018 IPR010342 Protein of unknown function DUF938 MKLM6_RS07655 3dceeb90f46016e8f962a304a8ade989 204 SUPERFAMILY SSF53335 17 190 2.67E-22 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS01185 c7b6617e056c48b8b4997647ce5ac085 324 Pfam PF01699 Sodium/calcium exchanger protein 174 318 8.3E-34 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 MKLM6_RS01185 c7b6617e056c48b8b4997647ce5ac085 324 Pfam PF01699 Sodium/calcium exchanger protein 5 141 1.4E-22 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 MKLM6_RS01185 c7b6617e056c48b8b4997647ce5ac085 324 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 5 313 2.1E-74 T 28-03-2018 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 MKLM6_RS20625 07a5e143c5ff525c00f935af11bc1739 281 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 82 95 - T 28-03-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 MKLM6_RS20625 07a5e143c5ff525c00f935af11bc1739 281 Pfam PF17284 Spermidine synthase tetramerisation domain 6 53 2.7E-15 T 28-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 MKLM6_RS20625 07a5e143c5ff525c00f935af11bc1739 281 Gene3D G3DSA:3.40.50.150 59 281 2.1E-33 T 28-03-2018 MKLM6_RS20625 07a5e143c5ff525c00f935af11bc1739 281 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 5 281 35.368 T 28-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 MKLM6_RS20625 07a5e143c5ff525c00f935af11bc1739 281 TIGRFAM TIGR00417 speE: spermidine synthase 6 275 7.0E-84 T 28-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 MKLM6_RS20625 07a5e143c5ff525c00f935af11bc1739 281 Pfam PF01564 Spermine/spermidine synthase domain 62 242 2.8E-49 T 28-03-2018 MKLM6_RS20625 07a5e143c5ff525c00f935af11bc1739 281 Gene3D G3DSA:2.30.140.10 6 54 1.1E-19 T 28-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 MKLM6_RS20625 07a5e143c5ff525c00f935af11bc1739 281 SUPERFAMILY SSF53335 5 279 1.22E-74 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS17670 bdeb13d58c0c5e3a7ceac862cbc2dc70 232 SUPERFAMILY SSF52172 6 187 8.82E-39 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS17670 bdeb13d58c0c5e3a7ceac862cbc2dc70 232 SMART SM00862 153 229 5.7E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS17670 bdeb13d58c0c5e3a7ceac862cbc2dc70 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 229 9.1E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS17670 bdeb13d58c0c5e3a7ceac862cbc2dc70 232 Pfam PF00072 Response regulator receiver domain 8 117 1.5E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS17670 bdeb13d58c0c5e3a7ceac862cbc2dc70 232 Gene3D G3DSA:1.10.10.10 128 231 1.8E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS17670 bdeb13d58c0c5e3a7ceac862cbc2dc70 232 Gene3D G3DSA:3.40.50.2300 1 127 3.4E-33 T 28-03-2018 MKLM6_RS17670 bdeb13d58c0c5e3a7ceac862cbc2dc70 232 SMART SM00448 6 116 7.6E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS15415 dea524fea610aec377aac428a435add6 157 Gene3D G3DSA:2.60.120.10 19 145 1.1E-16 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS15415 dea524fea610aec377aac428a435add6 157 Pfam PF00027 Cyclic nucleotide-binding domain 24 108 4.8E-14 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain MKLM6_RS15415 dea524fea610aec377aac428a435add6 157 SUPERFAMILY SSF51206 19 128 1.19E-18 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like MKLM6_RS15415 dea524fea610aec377aac428a435add6 157 SMART SM00100 4 125 2.8E-6 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain MKLM6_RS15415 dea524fea610aec377aac428a435add6 157 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 31 47 - T 28-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site MKLM6_RS03815 b963e0678333fd3e707d59735d16b1c6 397 Gene3D G3DSA:1.10.240.10 217 307 8.0E-27 T 28-03-2018 MKLM6_RS03815 b963e0678333fd3e707d59735d16b1c6 397 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 1 395 47.058 T 28-03-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 MKLM6_RS03815 b963e0678333fd3e707d59735d16b1c6 397 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 12 395 9.0E-121 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MKLM6_RS03815 b963e0678333fd3e707d59735d16b1c6 397 SUPERFAMILY SSF55174 296 394 1.11E-15 T 28-03-2018 MKLM6_RS03815 b963e0678333fd3e707d59735d16b1c6 397 Gene3D G3DSA:3.40.50.620 2 216 5.5E-60 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS03815 b963e0678333fd3e707d59735d16b1c6 397 SUPERFAMILY SSF52374 7 314 3.6E-96 T 28-03-2018 MKLM6_RS03815 b963e0678333fd3e707d59735d16b1c6 397 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 40 50 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS03815 b963e0678333fd3e707d59735d16b1c6 397 Pfam PF00579 tRNA synthetases class I (W and Y) 28 315 4.5E-82 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS03815 b963e0678333fd3e707d59735d16b1c6 397 SMART SM00363 335 396 4.6E-6 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MKLM6_RS03815 b963e0678333fd3e707d59735d16b1c6 397 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 159 174 7.2E-26 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MKLM6_RS03815 b963e0678333fd3e707d59735d16b1c6 397 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 176 198 7.2E-26 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MKLM6_RS03815 b963e0678333fd3e707d59735d16b1c6 397 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 44 66 7.2E-26 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MKLM6_RS03815 b963e0678333fd3e707d59735d16b1c6 397 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 209 221 7.2E-26 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MKLM6_RS03815 b963e0678333fd3e707d59735d16b1c6 397 Gene3D G3DSA:3.10.290.10 308 397 8.3E-20 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MKLM6_RS03815 b963e0678333fd3e707d59735d16b1c6 397 Pfam PF01479 S4 domain 336 376 1.0E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MKLM6_RS12260 c5e61e6985bfbe6d56ea508bf29c905a 236 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS12260 c5e61e6985bfbe6d56ea508bf29c905a 236 Pfam PF00005 ABC transporter 25 174 1.5E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS12260 c5e61e6985bfbe6d56ea508bf29c905a 236 Gene3D G3DSA:3.40.50.300 1 236 3.0E-64 T 28-03-2018 MKLM6_RS12260 c5e61e6985bfbe6d56ea508bf29c905a 236 SMART SM00382 34 222 2.7E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS12260 c5e61e6985bfbe6d56ea508bf29c905a 236 SUPERFAMILY SSF52540 5 228 7.86E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS03635 4f4dc5108b97fbd9af98dd156da533c3 621 Gene3D G3DSA:2.60.40.1180 523 618 0.0029 T 28-03-2018 MKLM6_RS03635 4f4dc5108b97fbd9af98dd156da533c3 621 SMART SM00642 122 516 2.0E-7 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MKLM6_RS03635 4f4dc5108b97fbd9af98dd156da533c3 621 Pfam PF00128 Alpha amylase, catalytic domain 158 474 8.9E-15 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MKLM6_RS03635 4f4dc5108b97fbd9af98dd156da533c3 621 Gene3D G3DSA:3.20.20.80 93 522 2.1E-52 T 28-03-2018 MKLM6_RS03635 4f4dc5108b97fbd9af98dd156da533c3 621 SUPERFAMILY SSF51445 139 261 7.35E-51 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily MKLM6_RS03635 4f4dc5108b97fbd9af98dd156da533c3 621 SUPERFAMILY SSF51445 295 522 7.35E-51 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily MKLM6_RS21955 d46d479242d052caf0edca8d37e615b5 428 Gene3D G3DSA:2.30.40.10 21 102 4.8E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MKLM6_RS21955 d46d479242d052caf0edca8d37e615b5 428 Gene3D G3DSA:2.30.40.10 347 423 6.7E-7 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MKLM6_RS21955 d46d479242d052caf0edca8d37e615b5 428 SUPERFAMILY SSF51338 44 99 5.32E-8 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MKLM6_RS21955 d46d479242d052caf0edca8d37e615b5 428 Pfam PF01979 Amidohydrolase family 85 420 5.1E-9 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MKLM6_RS21955 d46d479242d052caf0edca8d37e615b5 428 SUPERFAMILY SSF51556 89 383 8.46E-23 T 28-03-2018 IPR032466 Metal-dependent hydrolase MKLM6_RS21955 d46d479242d052caf0edca8d37e615b5 428 Gene3D G3DSA:3.20.20.140 103 273 1.7E-12 T 28-03-2018 MKLM6_RS21955 d46d479242d052caf0edca8d37e615b5 428 SUPERFAMILY SSF51338 366 421 7.2E-7 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MKLM6_RS09615 ebde213ce5d02c4cd1927c3db78cd111 2911 SUPERFAMILY SSF74650 2109 2375 2.13E-87 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 MKLM6_RS09615 ebde213ce5d02c4cd1927c3db78cd111 2911 Gene3D G3DSA:2.70.98.40 1617 1889 9.1E-86 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 MKLM6_RS09615 ebde213ce5d02c4cd1927c3db78cd111 2911 Gene3D G3DSA:2.70.98.40 2110 2387 4.5E-95 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 MKLM6_RS09615 ebde213ce5d02c4cd1927c3db78cd111 2911 SMART SM01068 2109 2174 1.6E-32 T 28-03-2018 IPR009342 Putative carbohydrate binding domain MKLM6_RS09615 ebde213ce5d02c4cd1927c3db78cd111 2911 SMART SM01068 1604 1665 9.9E-23 T 28-03-2018 IPR009342 Putative carbohydrate binding domain MKLM6_RS09615 ebde213ce5d02c4cd1927c3db78cd111 2911 Pfam PF06165 Glycosyltransferase family 36 1628 1874 1.8E-82 T 28-03-2018 IPR010383 Glycosyl hydrolase 94 MKLM6_RS09615 ebde213ce5d02c4cd1927c3db78cd111 2911 Pfam PF06165 Glycosyltransferase family 36 2132 2373 1.7E-80 T 28-03-2018 IPR010383 Glycosyl hydrolase 94 MKLM6_RS09615 ebde213ce5d02c4cd1927c3db78cd111 2911 SUPERFAMILY SSF48208 2391 2905 1.94E-101 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 MKLM6_RS09615 ebde213ce5d02c4cd1927c3db78cd111 2911 Pfam PF17167 Glycosyl hydrolase 36 superfamily, catalytic domain 2404 2829 1.9E-118 T 28-03-2018 IPR033432 Glycosyl hydrolase 36, catalytic domain MKLM6_RS09615 ebde213ce5d02c4cd1927c3db78cd111 2911 Gene3D G3DSA:1.50.10.10 2418 2793 3.6E-84 T 28-03-2018 MKLM6_RS09615 ebde213ce5d02c4cd1927c3db78cd111 2911 Gene3D G3DSA:2.60.420.10 2820 2904 3.9E-26 T 28-03-2018 MKLM6_RS09615 ebde213ce5d02c4cd1927c3db78cd111 2911 SUPERFAMILY SSF74650 1617 1877 4.39E-81 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 MKLM6_RS09615 ebde213ce5d02c4cd1927c3db78cd111 2911 Pfam PF10091 Putative glucoamylase 1365 1576 2.5E-13 T 28-03-2018 IPR019282 Domain of unknown function DUF2329 MKLM6_RS16545 9e4e88c3e9ee9d9a9bfdf2ae34a8f3ec 401 Pfam PF00563 EAL domain 80 191 5.3E-17 T 28-03-2018 IPR001633 EAL domain MKLM6_RS16545 9e4e88c3e9ee9d9a9bfdf2ae34a8f3ec 401 PIRSF PIRSF003180 1 395 5.9E-119 T 28-03-2018 IPR014408 Signal transduction c-di-GMP phosphodiesterase, EAL/HD-GYP domain-containing MKLM6_RS16545 9e4e88c3e9ee9d9a9bfdf2ae34a8f3ec 401 Pfam PF08668 HDOD domain 206 320 4.5E-18 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD MKLM6_RS16545 9e4e88c3e9ee9d9a9bfdf2ae34a8f3ec 401 Gene3D G3DSA:1.10.3210.10 195 326 8.2E-22 T 28-03-2018 MKLM6_RS16545 9e4e88c3e9ee9d9a9bfdf2ae34a8f3ec 401 SMART SM00052 2 196 2.0E-6 T 28-03-2018 IPR001633 EAL domain MKLM6_RS16545 9e4e88c3e9ee9d9a9bfdf2ae34a8f3ec 401 SUPERFAMILY SSF109604 182 392 7.22E-40 T 28-03-2018 MKLM6_RS16545 9e4e88c3e9ee9d9a9bfdf2ae34a8f3ec 401 SUPERFAMILY SSF141868 4 194 3.27E-31 T 28-03-2018 IPR001633 EAL domain MKLM6_RS16545 9e4e88c3e9ee9d9a9bfdf2ae34a8f3ec 401 Gene3D G3DSA:3.20.20.450 53 194 3.6E-25 T 28-03-2018 IPR001633 EAL domain MKLM6_RS06890 7b1b2613a1e75c1b0eac1d3b87b3e8d3 325 TIGRFAM TIGR00109 hemH: ferrochelatase 7 323 4.4E-96 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MKLM6_RS06890 7b1b2613a1e75c1b0eac1d3b87b3e8d3 325 Pfam PF00762 Ferrochelatase 8 323 7.3E-109 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MKLM6_RS06890 7b1b2613a1e75c1b0eac1d3b87b3e8d3 325 ProSitePatterns PS00534 Ferrochelatase signature. 194 214 - T 28-03-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MKLM6_RS06890 7b1b2613a1e75c1b0eac1d3b87b3e8d3 325 Hamap MF_00323 Ferrochelatase [hemH]. 7 325 37.186 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MKLM6_RS06890 7b1b2613a1e75c1b0eac1d3b87b3e8d3 325 Gene3D G3DSA:3.40.50.1400 178 305 1.4E-42 T 28-03-2018 MKLM6_RS06890 7b1b2613a1e75c1b0eac1d3b87b3e8d3 325 SUPERFAMILY SSF53800 7 323 3.92E-104 T 28-03-2018 MKLM6_RS06890 7b1b2613a1e75c1b0eac1d3b87b3e8d3 325 Gene3D G3DSA:3.40.50.1400 4 177 1.2E-48 T 28-03-2018 MKLM6_RS00125 9511edfb5a7aedac99ffd975822499c3 221 Pfam PF02586 SOS response associated peptidase (SRAP) 1 206 3.6E-65 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) MKLM6_RS00125 9511edfb5a7aedac99ffd975822499c3 221 Gene3D G3DSA:3.90.1680.10 1 221 1.6E-75 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) MKLM6_RS00125 9511edfb5a7aedac99ffd975822499c3 221 SUPERFAMILY SSF143081 2 216 1.83E-72 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) MKLM6_RS05755 75ffe332fdd193cf4fb0c4cb02b69266 405 SUPERFAMILY SSF52540 8 331 2.21E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS05755 75ffe332fdd193cf4fb0c4cb02b69266 405 Gene3D G3DSA:3.30.1220.10 246 379 1.0E-32 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MKLM6_RS05755 75ffe332fdd193cf4fb0c4cb02b69266 405 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 262 378 3.5E-28 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MKLM6_RS05755 75ffe332fdd193cf4fb0c4cb02b69266 405 Gene3D G3DSA:3.40.50.300 8 235 2.3E-51 T 28-03-2018 MKLM6_RS05755 75ffe332fdd193cf4fb0c4cb02b69266 405 SMART SM00833 262 378 1.6E-49 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MKLM6_RS05755 75ffe332fdd193cf4fb0c4cb02b69266 405 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 12 216 7.6E-55 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain MKLM6_RS14715 7567affa989a919a432f0d1050b45072 233 Gene3D G3DSA:3.40.50.2300 3 149 2.9E-28 T 28-03-2018 MKLM6_RS14715 7567affa989a919a432f0d1050b45072 233 Pfam PF00072 Response regulator receiver domain 5 115 4.8E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14715 7567affa989a919a432f0d1050b45072 233 SMART SM01248 139 221 1.5E-15 T 28-03-2018 IPR011649 KaiB domain GO:0048511 MKLM6_RS14715 7567affa989a919a432f0d1050b45072 233 SMART SM00448 3 117 2.5E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14715 7567affa989a919a432f0d1050b45072 233 Pfam PF07689 KaiB domain 146 211 2.4E-7 T 28-03-2018 IPR011649 KaiB domain GO:0048511 MKLM6_RS14715 7567affa989a919a432f0d1050b45072 233 SUPERFAMILY SSF52172 4 189 4.7E-27 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS14715 7567affa989a919a432f0d1050b45072 233 Gene3D G3DSA:3.40.30.10 150 218 1.7E-6 T 28-03-2018 MKLM6_RS15185 95ee41964f98220e5b2249ecd8baade0 193 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 31 190 1.6E-48 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MKLM6_RS15185 95ee41964f98220e5b2249ecd8baade0 193 SUPERFAMILY SSF50891 27 192 3.94E-58 T 28-03-2018 IPR029000 Cyclophilin-like domain MKLM6_RS15185 95ee41964f98220e5b2249ecd8baade0 193 PIRSF PIRSF001467 14 193 7.1E-27 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 MKLM6_RS15185 95ee41964f98220e5b2249ecd8baade0 193 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 70 82 3.3E-12 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MKLM6_RS15185 95ee41964f98220e5b2249ecd8baade0 193 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 44 59 3.3E-12 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MKLM6_RS15185 95ee41964f98220e5b2249ecd8baade0 193 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 147 162 3.3E-12 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MKLM6_RS15185 95ee41964f98220e5b2249ecd8baade0 193 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 65 82 - T 28-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 MKLM6_RS15185 95ee41964f98220e5b2249ecd8baade0 193 Gene3D G3DSA:2.40.100.10 12 193 1.2E-53 T 28-03-2018 IPR029000 Cyclophilin-like domain MKLM6_RS05765 5cac0316869d991284ac7adba82f5657 398 PIRSF PIRSF000722 1 397 5.6E-146 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MKLM6_RS05765 5cac0316869d991284ac7adba82f5657 398 Pfam PF00871 Acetokinase family 2 386 1.1E-143 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MKLM6_RS05765 5cac0316869d991284ac7adba82f5657 398 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 201 218 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MKLM6_RS05765 5cac0316869d991284ac7adba82f5657 398 Gene3D G3DSA:3.30.420.40 194 398 1.2E-78 T 28-03-2018 MKLM6_RS05765 5cac0316869d991284ac7adba82f5657 398 SUPERFAMILY SSF53067 155 391 2.89E-84 T 28-03-2018 MKLM6_RS05765 5cac0316869d991284ac7adba82f5657 398 Hamap MF_00020 Acetate kinase [ackA]. 1 396 176.187 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MKLM6_RS05765 5cac0316869d991284ac7adba82f5657 398 PRINTS PR00471 Acetate kinase family signature 374 386 1.0E-43 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MKLM6_RS05765 5cac0316869d991284ac7adba82f5657 398 PRINTS PR00471 Acetate kinase family signature 297 310 1.0E-43 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MKLM6_RS05765 5cac0316869d991284ac7adba82f5657 398 PRINTS PR00471 Acetate kinase family signature 201 222 1.0E-43 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MKLM6_RS05765 5cac0316869d991284ac7adba82f5657 398 PRINTS PR00471 Acetate kinase family signature 3 14 1.0E-43 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MKLM6_RS05765 5cac0316869d991284ac7adba82f5657 398 PRINTS PR00471 Acetate kinase family signature 319 335 1.0E-43 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MKLM6_RS05765 5cac0316869d991284ac7adba82f5657 398 PRINTS PR00471 Acetate kinase family signature 171 184 1.0E-43 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MKLM6_RS05765 5cac0316869d991284ac7adba82f5657 398 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 3 14 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MKLM6_RS05765 5cac0316869d991284ac7adba82f5657 398 Gene3D G3DSA:3.30.420.40 2 193 9.8E-73 T 28-03-2018 MKLM6_RS05765 5cac0316869d991284ac7adba82f5657 398 TIGRFAM TIGR00016 ackA: acetate kinase 1 390 7.9E-145 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MKLM6_RS05765 5cac0316869d991284ac7adba82f5657 398 SUPERFAMILY SSF53067 1 194 1.17E-66 T 28-03-2018 MKLM6_RS04295 8486a82010c459e6e4f232c7161edd0e 941 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 254 273 3.6E-13 T 28-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 MKLM6_RS04295 8486a82010c459e6e4f232c7161edd0e 941 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 481 495 3.6E-13 T 28-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 MKLM6_RS04295 8486a82010c459e6e4f232c7161edd0e 941 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 458 480 3.6E-13 T 28-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 MKLM6_RS04295 8486a82010c459e6e4f232c7161edd0e 941 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 192 204 3.6E-13 T 28-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 MKLM6_RS04295 8486a82010c459e6e4f232c7161edd0e 941 SUPERFAMILY SSF53335 165 205 3.23E-54 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS04295 8486a82010c459e6e4f232c7161edd0e 941 SUPERFAMILY SSF53335 242 356 3.23E-54 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS04295 8486a82010c459e6e4f232c7161edd0e 941 SUPERFAMILY SSF53335 440 525 3.23E-54 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS04295 8486a82010c459e6e4f232c7161edd0e 941 Pfam PF01555 DNA methylase 192 516 2.3E-31 T 28-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 MKLM6_RS04295 8486a82010c459e6e4f232c7161edd0e 941 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 195 201 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MKLM6_RS04295 8486a82010c459e6e4f232c7161edd0e 941 Gene3D G3DSA:3.40.50.150 167 526 5.8E-48 T 28-03-2018 MKLM6_RS15970 88db2457d8589e870e9dbb5a7d3d220d 102 Pfam PF09907 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system 22 92 1.1E-28 T 28-03-2018 IPR018669 Toxin-antitoxin system, toxin component, HigB, putative GO:0016788 MKLM6_RS12935 d94e2f8f2be35ebc83fac9def7666cd8 151 Gene3D G3DSA:3.90.1010.10 2 142 1.8E-48 T 28-03-2018 MKLM6_RS12935 d94e2f8f2be35ebc83fac9def7666cd8 151 SUPERFAMILY SSF82649 3 144 8.11E-47 T 28-03-2018 MKLM6_RS12935 d94e2f8f2be35ebc83fac9def7666cd8 151 Pfam PF01592 NifU-like N terminal domain 9 129 2.2E-22 T 28-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 MKLM6_RS12935 d94e2f8f2be35ebc83fac9def7666cd8 151 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 6 142 2.4E-46 T 28-03-2018 MKLM6_RS08905 44d0e6377c56a835c7176046287437e8 317 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 18 249 3.0E-40 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 MKLM6_RS08905 44d0e6377c56a835c7176046287437e8 317 Gene3D G3DSA:3.20.20.360 3 285 4.8E-64 T 28-03-2018 MKLM6_RS08905 44d0e6377c56a835c7176046287437e8 317 SUPERFAMILY SSF51621 12 260 7.18E-62 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MKLM6_RS08905 44d0e6377c56a835c7176046287437e8 317 PIRSF PIRSF015582 1 317 5.7E-82 T 28-03-2018 IPR011206 Citrate lyase beta subunit-like MKLM6_RS08725 7a3202e0263e5bbf4e11954f01156e6e 653 Gene3D G3DSA:1.20.120.140 349 449 1.3E-16 T 28-03-2018 MKLM6_RS08725 7a3202e0263e5bbf4e11954f01156e6e 653 Pfam PF02628 Cytochrome oxidase assembly protein 4 307 6.1E-69 T 28-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 MKLM6_RS08725 7a3202e0263e5bbf4e11954f01156e6e 653 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 380 650 5.4E-112 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 MKLM6_RS08725 7a3202e0263e5bbf4e11954f01156e6e 653 Gene3D G3DSA:3.40.50.300 450 556 4.3E-16 T 28-03-2018 MKLM6_RS08725 7a3202e0263e5bbf4e11954f01156e6e 653 SMART SM00962 450 651 2.0E-121 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MKLM6_RS08725 7a3202e0263e5bbf4e11954f01156e6e 653 Gene3D G3DSA:1.20.120.140 557 653 2.5E-22 T 28-03-2018 MKLM6_RS08725 7a3202e0263e5bbf4e11954f01156e6e 653 SMART SM00963 354 435 8.9E-14 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MKLM6_RS08725 7a3202e0263e5bbf4e11954f01156e6e 653 SMART SM00382 449 640 7.8E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS08725 7a3202e0263e5bbf4e11954f01156e6e 653 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 378 651 62.184 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 MKLM6_RS08725 7a3202e0263e5bbf4e11954f01156e6e 653 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 624 637 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MKLM6_RS08725 7a3202e0263e5bbf4e11954f01156e6e 653 Pfam PF00448 SRP54-type protein, GTPase domain 450 650 3.4E-78 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MKLM6_RS08725 7a3202e0263e5bbf4e11954f01156e6e 653 SUPERFAMILY SSF52540 446 649 2.01E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS08725 7a3202e0263e5bbf4e11954f01156e6e 653 Pfam PF02881 SRP54-type protein, helical bundle domain 365 431 2.7E-9 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MKLM6_RS08725 7a3202e0263e5bbf4e11954f01156e6e 653 SUPERFAMILY SSF47364 350 428 8.11E-15 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MKLM6_RS14880 997601cbabeed106a7eb31bf7873c545 113 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 8 104 8.5E-36 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS MKLM6_RS14880 997601cbabeed106a7eb31bf7873c545 113 Gene3D G3DSA:3.30.460.10 1 112 1.3E-34 T 28-03-2018 MKLM6_RS14880 997601cbabeed106a7eb31bf7873c545 113 Pfam PF02410 Ribosomal silencing factor during starvation 14 104 1.8E-27 T 28-03-2018 MKLM6_RS14880 997601cbabeed106a7eb31bf7873c545 113 SUPERFAMILY SSF81301 1 106 3.76E-36 T 28-03-2018 MKLM6_RS14880 997601cbabeed106a7eb31bf7873c545 113 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 23.96 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS MKLM6_RS17970 3b232c228b7fc75098119526fe0d7915 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 28-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS17970 3b232c228b7fc75098119526fe0d7915 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 8.3E-26 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS17970 3b232c228b7fc75098119526fe0d7915 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.594 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS17970 3b232c228b7fc75098119526fe0d7915 44 Pfam PF00468 Ribosomal protein L34 1 44 2.0E-24 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS17970 3b232c228b7fc75098119526fe0d7915 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 42 1.0E-11 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS10575 a1e8bf3ae589267fd1cf6d0aa30a1802 576 Pfam PF00270 DEAD/DEAH box helicase 35 200 2.5E-49 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MKLM6_RS10575 a1e8bf3ae589267fd1cf6d0aa30a1802 576 Pfam PF03880 DbpA RNA binding domain 480 549 4.4E-24 T 28-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain MKLM6_RS10575 a1e8bf3ae589267fd1cf6d0aa30a1802 576 Hamap MF_00964 ATP-dependent RNA helicase DeaD [deaD]. 5 551 46.67 T 28-03-2018 IPR028618 ATP-dependent RNA helicase DeaD GO:0000027|GO:0004004|GO:0070417 MKLM6_RS10575 a1e8bf3ae589267fd1cf6d0aa30a1802 576 SMART SM00490 263 344 2.0E-33 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS10575 a1e8bf3ae589267fd1cf6d0aa30a1802 576 Gene3D G3DSA:3.40.50.300 2 223 1.2E-60 T 28-03-2018 MKLM6_RS10575 a1e8bf3ae589267fd1cf6d0aa30a1802 576 SMART SM00487 29 227 4.4E-62 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MKLM6_RS10575 a1e8bf3ae589267fd1cf6d0aa30a1802 576 SUPERFAMILY SSF52540 78 366 9.21E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS10575 a1e8bf3ae589267fd1cf6d0aa30a1802 576 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 158 166 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MKLM6_RS10575 a1e8bf3ae589267fd1cf6d0aa30a1802 576 Pfam PF00271 Helicase conserved C-terminal domain 236 344 5.8E-29 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS10575 a1e8bf3ae589267fd1cf6d0aa30a1802 576 Gene3D G3DSA:3.40.50.300 224 379 1.0E-46 T 28-03-2018 MKLM6_RS15100 d51df19a04e80d461ca1537f4a8d155c 309 Gene3D G3DSA:1.10.3210.10 13 297 3.1E-41 T 28-03-2018 MKLM6_RS15100 d51df19a04e80d461ca1537f4a8d155c 309 Pfam PF08668 HDOD domain 38 238 9.0E-47 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD MKLM6_RS15100 d51df19a04e80d461ca1537f4a8d155c 309 SUPERFAMILY SSF109604 30 293 6.28E-60 T 28-03-2018 MKLM6_RS05575 6da0b572921f67864fb369d58b363d7f 83 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 19 53 4.4E-8 T 28-03-2018 MKLM6_RS05575 6da0b572921f67864fb369d58b363d7f 83 Gene3D G3DSA:3.40.1620.10 3 50 5.1E-11 T 28-03-2018 MKLM6_RS05575 6da0b572921f67864fb369d58b363d7f 83 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 4 67 2.7E-12 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MKLM6_RS05575 6da0b572921f67864fb369d58b363d7f 83 SUPERFAMILY SSF143120 4 51 4.05E-12 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MKLM6_RS00300 6b679b4a4fb88b64f8e755e11aff8587 97 SMART SM00465 3 81 1.5E-4 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily MKLM6_RS00300 6b679b4a4fb88b64f8e755e11aff8587 97 Pfam PF01541 GIY-YIG catalytic domain 5 76 2.1E-15 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily MKLM6_RS00300 6b679b4a4fb88b64f8e755e11aff8587 97 Gene3D G3DSA:3.40.1440.10 2 96 2.7E-19 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily MKLM6_RS00300 6b679b4a4fb88b64f8e755e11aff8587 97 SUPERFAMILY SSF82771 3 90 2.75E-22 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily MKLM6_RS00320 b5e8744c3d2af6db556cbeca5e510662 488 Pfam PF00571 CBS domain 148 202 5.9E-7 T 28-03-2018 IPR000644 CBS domain MKLM6_RS00320 b5e8744c3d2af6db556cbeca5e510662 488 Pfam PF00571 CBS domain 94 138 3.4E-11 T 28-03-2018 IPR000644 CBS domain MKLM6_RS00320 b5e8744c3d2af6db556cbeca5e510662 488 SMART SM00116 156 204 1.8E-6 T 28-03-2018 IPR000644 CBS domain MKLM6_RS00320 b5e8744c3d2af6db556cbeca5e510662 488 SMART SM00116 95 142 1.3E-11 T 28-03-2018 IPR000644 CBS domain MKLM6_RS00320 b5e8744c3d2af6db556cbeca5e510662 488 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 7 456 2.2E-193 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MKLM6_RS00320 b5e8744c3d2af6db556cbeca5e510662 488 SUPERFAMILY SSF54631 93 202 1.34E-27 T 28-03-2018 MKLM6_RS00320 b5e8744c3d2af6db556cbeca5e510662 488 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 7 487 85.709 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MKLM6_RS00320 b5e8744c3d2af6db556cbeca5e510662 488 Gene3D G3DSA:3.20.20.70 2 485 2.9E-123 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS00320 b5e8744c3d2af6db556cbeca5e510662 488 SUPERFAMILY SSF51412 215 478 2.75E-128 T 28-03-2018 MKLM6_RS00320 b5e8744c3d2af6db556cbeca5e510662 488 SUPERFAMILY SSF51412 3 89 2.75E-128 T 28-03-2018 MKLM6_RS00320 b5e8744c3d2af6db556cbeca5e510662 488 PIRSF PIRSF000130 1 488 4.8E-209 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MKLM6_RS00320 b5e8744c3d2af6db556cbeca5e510662 488 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 7 474 1.2E-166 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 MKLM6_RS00320 b5e8744c3d2af6db556cbeca5e510662 488 SMART SM01240 6 474 0.0 T 28-03-2018 MKLM6_RS00320 b5e8744c3d2af6db556cbeca5e510662 488 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 293 305 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 MKLM6_RS08675 b587f9b8e09b9474ec846a938d64eeb5 261 Pfam PF08241 Methyltransferase domain 51 144 2.4E-21 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MKLM6_RS08675 b587f9b8e09b9474ec846a938d64eeb5 261 SUPERFAMILY SSF53335 12 248 2.28E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS08675 b587f9b8e09b9474ec846a938d64eeb5 261 Gene3D G3DSA:3.40.50.150 43 261 8.0E-33 T 28-03-2018 MKLM6_RS08675 b587f9b8e09b9474ec846a938d64eeb5 261 TIGRFAM TIGR02072 BioC: malonyl-acyl carrier protein O-methyltransferase BioC 15 259 3.6E-62 T 28-03-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 MKLM6_RS08675 b587f9b8e09b9474ec846a938d64eeb5 261 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 7 261 29.186 T 28-03-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 MKLM6_RS18865 d5c1c688ca4cb4cfd388eb0bc5a2d9d1 299 Pfam PF04085 rod shape-determining protein MreC 127 269 5.9E-36 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 MKLM6_RS18865 d5c1c688ca4cb4cfd388eb0bc5a2d9d1 299 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 5 274 8.4E-56 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 MKLM6_RS18865 d5c1c688ca4cb4cfd388eb0bc5a2d9d1 299 PIRSF PIRSF038471 3 283 4.8E-77 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 SUPERFAMILY SSF82693 672 722 3.66E-23 T 28-03-2018 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 SUPERFAMILY SSF82693 809 858 3.66E-23 T 28-03-2018 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 Gene3D G3DSA:3.30.70.1320 137 198 2.1E-4 T 28-03-2018 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 SUPERFAMILY SSF82866 297 498 1.26E-49 T 28-03-2018 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 Gene3D G3DSA:1.20.1640.10 287 510 2.0E-49 T 28-03-2018 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 SUPERFAMILY SSF82693 569 671 2.88E-22 T 28-03-2018 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 PRINTS PR00702 Acriflavin resistance protein family signature 446 469 1.8E-87 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 PRINTS PR00702 Acriflavin resistance protein family signature 471 494 1.8E-87 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 PRINTS PR00702 Acriflavin resistance protein family signature 337 360 1.8E-87 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 PRINTS PR00702 Acriflavin resistance protein family signature 392 416 1.8E-87 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 PRINTS PR00702 Acriflavin resistance protein family signature 556 573 1.8E-87 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 PRINTS PR00702 Acriflavin resistance protein family signature 625 639 1.8E-87 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 PRINTS PR00702 Acriflavin resistance protein family signature 364 385 1.8E-87 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 1.8E-87 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 1.8E-87 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 Gene3D G3DSA:3.30.2090.10 199 273 4.7E-10 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 Gene3D G3DSA:1.20.1640.10 811 1031 4.5E-39 T 28-03-2018 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 Gene3D G3DSA:3.30.70.1430 38 136 5.0E-19 T 28-03-2018 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 SUPERFAMILY SSF82714 723 807 3.27E-11 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 SUPERFAMILY SSF82693 275 331 1.03E-20 T 28-03-2018 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 SUPERFAMILY SSF82693 135 182 1.03E-20 T 28-03-2018 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 SUPERFAMILY SSF82714 183 272 9.94E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 Gene3D G3DSA:3.30.70.1430 571 671 1.7E-20 T 28-03-2018 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 SUPERFAMILY SSF82693 38 123 1.99E-18 T 28-03-2018 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1040 3.2E-304 T 28-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 Pfam PF00873 AcrB/AcrD/AcrF family 1 1027 3.2E-288 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 Gene3D G3DSA:3.30.70.1440 672 769 3.1E-11 T 28-03-2018 MKLM6_RS14430 3fdfac128aa9977040d2c636bfa0f00b 1058 SUPERFAMILY SSF82866 832 1028 2.62E-44 T 28-03-2018 MKLM6_RS21970 3af3151a8f2d82b3c652628b1e311bd1 251 Pfam PF00498 FHA domain 44 108 1.9E-15 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MKLM6_RS21970 3af3151a8f2d82b3c652628b1e311bd1 251 SMART SM00240 43 93 2.0E-12 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MKLM6_RS21970 3af3151a8f2d82b3c652628b1e311bd1 251 SUPERFAMILY SSF49879 17 117 2.49E-24 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MKLM6_RS21970 3af3151a8f2d82b3c652628b1e311bd1 251 SUPERFAMILY SSF49879 160 248 2.28E-10 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MKLM6_RS21970 3af3151a8f2d82b3c652628b1e311bd1 251 Gene3D G3DSA:2.60.200.20 158 251 1.2E-6 T 28-03-2018 MKLM6_RS21970 3af3151a8f2d82b3c652628b1e311bd1 251 Gene3D G3DSA:2.60.200.20 20 137 1.8E-22 T 28-03-2018 MKLM6_RS16630 cdac9a3d6873ca8ace22549180eb698c 772 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 13 185 2.9E-40 T 28-03-2018 IPR025199 DNA translocase FtsK, 4TM region MKLM6_RS16630 cdac9a3d6873ca8ace22549180eb698c 772 SUPERFAMILY SSF52540 364 677 7.04E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS16630 cdac9a3d6873ca8ace22549180eb698c 772 Pfam PF01580 FtsK/SpoIIIE family 390 604 3.9E-66 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MKLM6_RS16630 cdac9a3d6873ca8ace22549180eb698c 772 SMART SM00843 706 771 1.0E-41 T 28-03-2018 IPR018541 FtsK gamma domain MKLM6_RS16630 cdac9a3d6873ca8ace22549180eb698c 772 Pfam PF09397 Ftsk gamma domain 708 768 1.9E-28 T 28-03-2018 IPR018541 FtsK gamma domain MKLM6_RS16630 cdac9a3d6873ca8ace22549180eb698c 772 Gene3D G3DSA:3.40.50.300 219 650 1.0E-54 T 28-03-2018 MKLM6_RS16630 cdac9a3d6873ca8ace22549180eb698c 772 SUPERFAMILY SSF46785 706 770 1.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS16630 cdac9a3d6873ca8ace22549180eb698c 772 Gene3D G3DSA:1.10.10.10 708 762 6.4E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS10385 e23f34c8fa6da1e050cdcb86a16a57b9 3368 Gene3D G3DSA:2.160.20.10 665 872 3.9E-9 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS10385 e23f34c8fa6da1e050cdcb86a16a57b9 3368 Gene3D G3DSA:2.160.20.10 342 654 6.3E-4 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS10385 e23f34c8fa6da1e050cdcb86a16a57b9 3368 Gene3D G3DSA:2.160.20.10 1306 1833 9.0E-7 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS10385 e23f34c8fa6da1e050cdcb86a16a57b9 3368 Gene3D G3DSA:2.160.20.10 1963 2169 0.026 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS10385 e23f34c8fa6da1e050cdcb86a16a57b9 3368 Gene3D G3DSA:2.160.20.10 41 341 7.9E-40 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS10385 e23f34c8fa6da1e050cdcb86a16a57b9 3368 Pfam PF05860 haemagglutination activity domain 51 155 6.8E-20 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MKLM6_RS10385 e23f34c8fa6da1e050cdcb86a16a57b9 3368 Pfam PF12545 Filamentous haemagglutinin family outer membrane protein 3202 3311 6.0E-39 T 28-03-2018 IPR021026 Filamentous haemagglutinin family outer membrane protein, domain of unknown function DUF3739 MKLM6_RS10385 e23f34c8fa6da1e050cdcb86a16a57b9 3368 Gene3D G3DSA:2.160.20.20 946 1279 0.0068 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like MKLM6_RS10385 e23f34c8fa6da1e050cdcb86a16a57b9 3368 SUPERFAMILY SSF51126 57 314 5.02E-26 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS10385 e23f34c8fa6da1e050cdcb86a16a57b9 3368 SMART SM00912 48 156 7.2E-26 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MKLM6_RS10385 e23f34c8fa6da1e050cdcb86a16a57b9 3368 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 78 153 6.7E-21 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MKLM6_RS03240 d68d4d64c228732aea94793d41c40bca 67 Gene3D G3DSA:2.40.50.140 1 66 3.8E-27 T 28-03-2018 MKLM6_RS03240 d68d4d64c228732aea94793d41c40bca 67 SMART SM00357 3 67 4.6E-25 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 MKLM6_RS03240 d68d4d64c228732aea94793d41c40bca 67 SUPERFAMILY SSF50249 1 65 4.07E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS03240 d68d4d64c228732aea94793d41c40bca 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 4.5E-28 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MKLM6_RS03240 d68d4d64c228732aea94793d41c40bca 67 PIRSF PIRSF002599 1 67 2.6E-22 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 MKLM6_RS03240 d68d4d64c228732aea94793d41c40bca 67 PRINTS PR00050 Cold shock protein signature 40 58 9.0E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MKLM6_RS03240 d68d4d64c228732aea94793d41c40bca 67 PRINTS PR00050 Cold shock protein signature 4 19 9.0E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MKLM6_RS03240 d68d4d64c228732aea94793d41c40bca 67 PRINTS PR00050 Cold shock protein signature 25 34 9.0E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MKLM6_RS03240 d68d4d64c228732aea94793d41c40bca 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 28-03-2018 IPR019844 Cold-shock conserved site MKLM6_RS00785 0ca0d2c7c03ce87c1b258cda87790b73 274 Gene3D G3DSA:3.40.50.1860 4 116 2.6E-29 T 28-03-2018 MKLM6_RS00785 0ca0d2c7c03ce87c1b258cda87790b73 274 SUPERFAMILY SSF53681 110 259 6.38E-34 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS00785 0ca0d2c7c03ce87c1b258cda87790b73 274 TIGRFAM TIGR00067 glut_race: glutamate racemase 8 237 2.3E-60 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS00785 0ca0d2c7c03ce87c1b258cda87790b73 274 Gene3D G3DSA:3.40.50.1860 117 266 1.6E-38 T 28-03-2018 MKLM6_RS00785 0ca0d2c7c03ce87c1b258cda87790b73 274 Hamap MF_00258 Glutamate racemase [murI]. 6 255 33.513 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS00785 0ca0d2c7c03ce87c1b258cda87790b73 274 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 216 1.6E-35 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS00785 0ca0d2c7c03ce87c1b258cda87790b73 274 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 181 191 - T 28-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS00785 0ca0d2c7c03ce87c1b258cda87790b73 274 SUPERFAMILY SSF53681 7 108 2.26E-32 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS00785 0ca0d2c7c03ce87c1b258cda87790b73 274 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 72 80 - T 28-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS13320 d75311d49ca9f98eb47401230ff4d9a8 406 PIRSF PIRSF004640 1 406 2.1E-130 T 28-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MKLM6_RS13320 d75311d49ca9f98eb47401230ff4d9a8 406 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 6 395 3.9E-117 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MKLM6_RS13320 d75311d49ca9f98eb47401230ff4d9a8 406 Pfam PF04551 GcpE protein 9 396 2.1E-113 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MKLM6_RS13320 d75311d49ca9f98eb47401230ff4d9a8 406 Gene3D G3DSA:3.20.20.70 5 384 4.3E-5 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS13320 d75311d49ca9f98eb47401230ff4d9a8 406 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 4 398 29.293 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MKLM6_RS17370 f177cb9ad0366728b083066714b81c4b 291 PIRSF PIRSF000363 3 279 2.1E-125 T 28-03-2018 IPR000392 NifH/frxC family GO:0005524|GO:0016491|GO:0055114 MKLM6_RS17370 f177cb9ad0366728b083066714b81c4b 291 PRINTS PR00091 Nitrogenase component II signature 32 47 8.4E-38 T 28-03-2018 MKLM6_RS17370 f177cb9ad0366728b083066714b81c4b 291 PRINTS PR00091 Nitrogenase component II signature 126 141 8.4E-38 T 28-03-2018 MKLM6_RS17370 f177cb9ad0366728b083066714b81c4b 291 PRINTS PR00091 Nitrogenase component II signature 10 23 8.4E-38 T 28-03-2018 MKLM6_RS17370 f177cb9ad0366728b083066714b81c4b 291 PRINTS PR00091 Nitrogenase component II signature 87 101 8.4E-38 T 28-03-2018 MKLM6_RS17370 f177cb9ad0366728b083066714b81c4b 291 Pfam PF00142 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family 5 276 4.2E-139 T 28-03-2018 IPR000392 NifH/frxC family GO:0005524|GO:0016491|GO:0055114 MKLM6_RS17370 f177cb9ad0366728b083066714b81c4b 291 TIGRFAM TIGR01287 nifH: nitrogenase iron protein 5 279 1.6E-142 T 28-03-2018 IPR005977 Nitrogenase iron protein NifH GO:0009399|GO:0016163|GO:0016612|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 MKLM6_RS17370 f177cb9ad0366728b083066714b81c4b 291 Hamap MF_00533 Nitrogenase iron protein [nifH]. 4 277 52.24 T 28-03-2018 IPR005977 Nitrogenase iron protein NifH GO:0009399|GO:0016163|GO:0016612|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 MKLM6_RS17370 f177cb9ad0366728b083066714b81c4b 291 Gene3D G3DSA:3.40.50.300 5 273 6.1E-45 T 28-03-2018 MKLM6_RS17370 f177cb9ad0366728b083066714b81c4b 291 SUPERFAMILY SSF52540 7 279 4.41E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS17370 f177cb9ad0366728b083066714b81c4b 291 ProSitePatterns PS00692 NifH/frxC family signature 2. 127 140 - T 28-03-2018 IPR030655 NifH/chlL conserved site MKLM6_RS17370 f177cb9ad0366728b083066714b81c4b 291 ProSitePatterns PS00746 NifH/frxC family signature 1. 89 101 - T 28-03-2018 IPR030655 NifH/chlL conserved site MKLM6_RS01835 516399083a06798ffea10102bcc6936f 277 SUPERFAMILY SSF51735 4 272 5.42E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS01835 516399083a06798ffea10102bcc6936f 277 Gene3D G3DSA:3.40.50.720 3 266 2.0E-59 T 28-03-2018 MKLM6_RS01835 516399083a06798ffea10102bcc6936f 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 6.0E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS01835 516399083a06798ffea10102bcc6936f 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 6.0E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS01835 516399083a06798ffea10102bcc6936f 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 6.0E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS01835 516399083a06798ffea10102bcc6936f 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 6.0E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS01835 516399083a06798ffea10102bcc6936f 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 6.0E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS01835 516399083a06798ffea10102bcc6936f 277 Pfam PF00106 short chain dehydrogenase 5 190 1.0E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS01835 516399083a06798ffea10102bcc6936f 277 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MKLM6_RS15625 d590cff9beb89a3839767a54303cd539 196 Gene3D G3DSA:3.30.420.10 3 196 8.4E-65 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS15625 d590cff9beb89a3839767a54303cd539 196 SUPERFAMILY SSF53098 11 196 3.95E-66 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS15625 d590cff9beb89a3839767a54303cd539 196 Hamap MF_00052_B Ribonuclease HII [rnhB]. 13 192 37.586 T 28-03-2018 IPR022898 Ribonuclease HII GO:0004523 MKLM6_RS15625 d590cff9beb89a3839767a54303cd539 196 Pfam PF01351 Ribonuclease HII 15 191 2.4E-40 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain MKLM6_RS10525 f26b91fb2cb46a0f15c8043896c05740 325 TIGRFAM TIGR01139 cysK: cysteine synthase A 9 314 4.4E-138 T 28-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MKLM6_RS10525 f26b91fb2cb46a0f15c8043896c05740 325 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 303 6.4E-66 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MKLM6_RS10525 f26b91fb2cb46a0f15c8043896c05740 325 Gene3D G3DSA:3.40.50.1100 43 138 1.0E-31 T 28-03-2018 MKLM6_RS10525 f26b91fb2cb46a0f15c8043896c05740 325 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 314 1.1E-133 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MKLM6_RS10525 f26b91fb2cb46a0f15c8043896c05740 325 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 34 52 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 MKLM6_RS10525 f26b91fb2cb46a0f15c8043896c05740 325 SUPERFAMILY SSF53686 4 311 7.2E-97 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MKLM6_RS10525 f26b91fb2cb46a0f15c8043896c05740 325 Gene3D G3DSA:3.40.50.1100 139 318 4.6E-59 T 28-03-2018 MKLM6_RS17770 b0c15238fbf2fc6dde8ffdc9f76da457 135 SUPERFAMILY SSF88723 1 132 1.18E-27 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS17770 b0c15238fbf2fc6dde8ffdc9f76da457 135 Pfam PF01850 PIN domain 2 117 1.2E-14 T 28-03-2018 IPR002716 PIN domain MKLM6_RS17770 b0c15238fbf2fc6dde8ffdc9f76da457 135 Gene3D G3DSA:3.40.50.1010 1 134 4.8E-29 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS09370 2a89f6ca6f4245215a10461e2f3f36d2 613 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 220 233 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MKLM6_RS09370 2a89f6ca6f4245215a10461e2f3f36d2 613 Pfam PF00012 Hsp70 protein 127 339 1.4E-16 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MKLM6_RS09370 2a89f6ca6f4245215a10461e2f3f36d2 613 SUPERFAMILY SSF53067 215 366 9.51E-26 T 28-03-2018 MKLM6_RS09370 2a89f6ca6f4245215a10461e2f3f36d2 613 SUPERFAMILY SSF53067 402 461 9.51E-26 T 28-03-2018 MKLM6_RS09370 2a89f6ca6f4245215a10461e2f3f36d2 613 Gene3D G3DSA:3.30.420.40 4 224 8.7E-33 T 28-03-2018 MKLM6_RS09370 2a89f6ca6f4245215a10461e2f3f36d2 613 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 10 17 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MKLM6_RS09370 2a89f6ca6f4245215a10461e2f3f36d2 613 SUPERFAMILY SSF53067 5 201 4.89E-28 T 28-03-2018 MKLM6_RS09370 2a89f6ca6f4245215a10461e2f3f36d2 613 PRINTS PR00301 70kDa heat shock protein signature 226 236 2.2E-9 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MKLM6_RS09370 2a89f6ca6f4245215a10461e2f3f36d2 613 PRINTS PR00301 70kDa heat shock protein signature 6 19 2.2E-9 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MKLM6_RS09370 2a89f6ca6f4245215a10461e2f3f36d2 613 PRINTS PR00301 70kDa heat shock protein signature 159 179 2.2E-9 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MKLM6_RS09370 2a89f6ca6f4245215a10461e2f3f36d2 613 PRINTS PR00301 70kDa heat shock protein signature 402 422 2.2E-9 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MKLM6_RS09370 2a89f6ca6f4245215a10461e2f3f36d2 613 Gene3D G3DSA:3.30.420.40 225 430 4.0E-16 T 28-03-2018 MKLM6_RS02155 170207f0c9ba1ab62927c7c0808dc02d 429 Pfam PF01595 Domain of unknown function DUF21 5 196 2.2E-45 T 28-03-2018 IPR002550 Domain of unknown function DUF21 MKLM6_RS02155 170207f0c9ba1ab62927c7c0808dc02d 429 Pfam PF03471 Transporter associated domain 344 425 1.6E-18 T 28-03-2018 IPR005170 Transporter-associated domain MKLM6_RS02155 170207f0c9ba1ab62927c7c0808dc02d 429 Gene3D G3DSA:3.20.20.70 140 351 3.7E-19 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS02155 170207f0c9ba1ab62927c7c0808dc02d 429 Gene3D G3DSA:3.30.465.10 352 429 1.1E-20 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MKLM6_RS02155 170207f0c9ba1ab62927c7c0808dc02d 429 SUPERFAMILY SSF54631 199 333 1.77E-21 T 28-03-2018 MKLM6_RS02155 170207f0c9ba1ab62927c7c0808dc02d 429 SUPERFAMILY SSF56176 342 424 2.04E-20 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MKLM6_RS02155 170207f0c9ba1ab62927c7c0808dc02d 429 Pfam PF00571 CBS domain 283 330 1.9E-6 T 28-03-2018 IPR000644 CBS domain MKLM6_RS02155 170207f0c9ba1ab62927c7c0808dc02d 429 SMART SM01091 343 426 5.7E-23 T 28-03-2018 IPR005170 Transporter-associated domain MKLM6_RS03790 8af38cfd0dbbda82451d122e2980fc25 379 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 284 370 8.7E-7 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain MKLM6_RS03790 8af38cfd0dbbda82451d122e2980fc25 379 PIRSF PIRSF037420 14 379 1.8E-130 T 28-03-2018 MKLM6_RS03790 8af38cfd0dbbda82451d122e2980fc25 379 Gene3D G3DSA:3.20.20.70 20 333 3.8E-45 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS03790 8af38cfd0dbbda82451d122e2980fc25 379 SUPERFAMILY SSF102114 17 350 1.7E-66 T 28-03-2018 MKLM6_RS03790 8af38cfd0dbbda82451d122e2980fc25 379 Pfam PF04055 Radical SAM superfamily 32 177 1.6E-19 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS03790 8af38cfd0dbbda82451d122e2980fc25 379 Pfam PF13353 4Fe-4S single cluster domain 28 146 1.5E-9 T 28-03-2018 MKLM6_RS03790 8af38cfd0dbbda82451d122e2980fc25 379 TIGRFAM TIGR04051 rSAM_NirJ: heme d1 biosynthesis radical SAM protein NirJ 25 377 2.6E-189 T 28-03-2018 IPR023992 Heme D1 biosynthesis, radical SAM protein NirJ MKLM6_RS15105 fc364fd479678fae2664c73e32c2d48b 431 Gene3D G3DSA:1.10.10.60 358 431 2.4E-10 T 28-03-2018 MKLM6_RS15105 fc364fd479678fae2664c73e32c2d48b 431 Pfam PF02954 Bacterial regulatory protein, Fis family 388 427 1.8E-5 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS15105 fc364fd479678fae2664c73e32c2d48b 431 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 332 341 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site MKLM6_RS15105 fc364fd479678fae2664c73e32c2d48b 431 Pfam PF00158 Sigma-54 interaction domain 121 287 3.9E-63 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MKLM6_RS15105 fc364fd479678fae2664c73e32c2d48b 431 SMART SM00382 141 293 2.7E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS15105 fc364fd479678fae2664c73e32c2d48b 431 SUPERFAMILY SSF46689 332 430 2.47E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS15105 fc364fd479678fae2664c73e32c2d48b 431 Gene3D G3DSA:1.10.8.60 294 357 1.9E-17 T 28-03-2018 MKLM6_RS15105 fc364fd479678fae2664c73e32c2d48b 431 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 207 222 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MKLM6_RS15105 fc364fd479678fae2664c73e32c2d48b 431 Gene3D G3DSA:3.30.450.20 3 106 1.2E-5 T 28-03-2018 MKLM6_RS15105 fc364fd479678fae2664c73e32c2d48b 431 SUPERFAMILY SSF55785 8 67 5.33E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS15105 fc364fd479678fae2664c73e32c2d48b 431 SUPERFAMILY SSF52540 121 360 3.82E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS15105 fc364fd479678fae2664c73e32c2d48b 431 Gene3D G3DSA:3.40.50.300 116 293 6.4E-26 T 28-03-2018 MKLM6_RS07750 63e4ae0c4275f96520e1246984889605 451 Pfam PF07690 Major Facilitator Superfamily 13 349 7.1E-43 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MKLM6_RS07750 63e4ae0c4275f96520e1246984889605 451 Gene3D G3DSA:1.20.1250.20 1 194 5.0E-33 T 28-03-2018 MKLM6_RS07750 63e4ae0c4275f96520e1246984889605 451 Gene3D G3DSA:1.20.1250.20 195 388 4.5E-20 T 28-03-2018 MKLM6_RS07750 63e4ae0c4275f96520e1246984889605 451 SUPERFAMILY SSF103473 6 387 3.4E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain MKLM6_RS03175 997314fa254a8c889f9d34a98de10589 396 SUPERFAMILY SSF52507 1 167 8.63E-61 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MKLM6_RS03175 997314fa254a8c889f9d34a98de10589 396 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 1 383 8.0E-139 T 28-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 MKLM6_RS03175 997314fa254a8c889f9d34a98de10589 396 Gene3D G3DSA:3.40.50.10300 172 392 5.1E-66 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MKLM6_RS03175 997314fa254a8c889f9d34a98de10589 396 Pfam PF02441 Flavoprotein 1 168 3.9E-47 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MKLM6_RS03175 997314fa254a8c889f9d34a98de10589 396 SUPERFAMILY SSF102645 174 388 4.71E-74 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MKLM6_RS03175 997314fa254a8c889f9d34a98de10589 396 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 176 358 8.6E-69 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MKLM6_RS03175 997314fa254a8c889f9d34a98de10589 396 Gene3D G3DSA:3.40.50.1950 1 171 2.6E-59 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MKLM6_RS10505 de10bceb5d5a52ba7bc9f9bdddf6ff97 275 Gene3D G3DSA:1.10.3720.10 13 274 7.8E-48 T 28-03-2018 MKLM6_RS10505 de10bceb5d5a52ba7bc9f9bdddf6ff97 275 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 7 270 1.7E-116 T 28-03-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 MKLM6_RS10505 de10bceb5d5a52ba7bc9f9bdddf6ff97 275 SUPERFAMILY SSF161098 11 262 1.21E-52 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MKLM6_RS10505 de10bceb5d5a52ba7bc9f9bdddf6ff97 275 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 10 266 1.9E-91 T 28-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 MKLM6_RS10505 de10bceb5d5a52ba7bc9f9bdddf6ff97 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 271 7.9E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MKLM6_RS11175 e85bfa8aa56153e99b68cbe70850901c 501 Pfam PF02120 Flagellar hook-length control protein FliK 410 485 5.1E-12 T 28-03-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal MKLM6_RS14725 be9fca7710e011daade2fd4cca6cf526 223 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 216 5.3E-98 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MKLM6_RS14725 be9fca7710e011daade2fd4cca6cf526 223 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 136 158 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MKLM6_RS14725 be9fca7710e011daade2fd4cca6cf526 223 PIRSF PIRSF001461 1 223 5.6E-104 T 28-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MKLM6_RS14725 be9fca7710e011daade2fd4cca6cf526 223 SUPERFAMILY SSF51366 5 218 2.25E-75 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MKLM6_RS14725 be9fca7710e011daade2fd4cca6cf526 223 Gene3D G3DSA:3.20.20.70 2 220 1.7E-86 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS14725 be9fca7710e011daade2fd4cca6cf526 223 Pfam PF00834 Ribulose-phosphate 3 epimerase family 6 203 4.6E-91 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MKLM6_RS14725 be9fca7710e011daade2fd4cca6cf526 223 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MKLM6_RS15335 e81203785e1ec911d60ee66ae88e21f7 401 Pfam PF13692 Glycosyl transferases group 1 218 361 3.0E-28 T 28-03-2018 MKLM6_RS15335 e81203785e1ec911d60ee66ae88e21f7 401 Pfam PF13579 Glycosyl transferase 4-like domain 15 190 8.9E-23 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MKLM6_RS15335 e81203785e1ec911d60ee66ae88e21f7 401 SUPERFAMILY SSF53756 2 397 8.72E-72 T 28-03-2018 MKLM6_RS15335 e81203785e1ec911d60ee66ae88e21f7 401 TIGRFAM TIGR04063 stp3: PEP-CTERM/exosortase A-associated glycosyltransferase, Daro_2409 family 2 397 6.7E-188 T 28-03-2018 IPR024004 Glycosyltransferase family 1, Daro2409 family MKLM6_RS15335 e81203785e1ec911d60ee66ae88e21f7 401 Gene3D G3DSA:3.40.50.2000 4 203 5.2E-22 T 28-03-2018 MKLM6_RS15335 e81203785e1ec911d60ee66ae88e21f7 401 Gene3D G3DSA:3.40.50.2000 204 380 1.3E-35 T 28-03-2018 MKLM6_RS03075 ff4f70d4e0cee8c262ed566cb63aeb6e 230 Gene3D G3DSA:3.40.50.2300 1 125 9.7E-37 T 28-03-2018 MKLM6_RS03075 ff4f70d4e0cee8c262ed566cb63aeb6e 230 Gene3D G3DSA:1.10.10.10 126 229 1.5E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS03075 ff4f70d4e0cee8c262ed566cb63aeb6e 230 SMART SM00862 151 226 3.4E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS03075 ff4f70d4e0cee8c262ed566cb63aeb6e 230 SUPERFAMILY SSF52172 1 188 6.88E-44 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS03075 ff4f70d4e0cee8c262ed566cb63aeb6e 230 SMART SM00448 4 117 1.2E-43 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS03075 ff4f70d4e0cee8c262ed566cb63aeb6e 230 Pfam PF00072 Response regulator receiver domain 6 118 1.0E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS03075 ff4f70d4e0cee8c262ed566cb63aeb6e 230 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 4 227 1.5E-99 T 28-03-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 MKLM6_RS03075 ff4f70d4e0cee8c262ed566cb63aeb6e 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 226 6.7E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS14915 7bd1fa945dd06bd67e5455b640d24108 220 Pfam PF00034 Cytochrome c 45 119 7.4E-7 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS14915 7bd1fa945dd06bd67e5455b640d24108 220 PIRSF PIRSF000005 4 220 1.1E-52 T 28-03-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 MKLM6_RS14915 7bd1fa945dd06bd67e5455b640d24108 220 SUPERFAMILY SSF46626 132 216 9.61E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS14915 7bd1fa945dd06bd67e5455b640d24108 220 Gene3D G3DSA:1.10.760.10 16 119 4.2E-19 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS14915 7bd1fa945dd06bd67e5455b640d24108 220 Gene3D G3DSA:1.10.760.10 122 217 7.0E-14 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS14915 7bd1fa945dd06bd67e5455b640d24108 220 SUPERFAMILY SSF46626 51 120 4.22E-19 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS22330 d4768e4761857c3ddac05ef6afb911b4 870 Pfam PF13166 AAA domain 384 705 2.4E-21 T 28-03-2018 IPR026866 Protein CR006, P-loop domain MKLM6_RS22330 d4768e4761857c3ddac05ef6afb911b4 870 SUPERFAMILY SSF52540 85 211 5.16E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS22330 d4768e4761857c3ddac05ef6afb911b4 870 SUPERFAMILY SSF52540 576 699 5.16E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS22330 d4768e4761857c3ddac05ef6afb911b4 870 Gene3D G3DSA:3.40.50.300 80 703 2.7E-22 T 28-03-2018 MKLM6_RS20210 7d154dde41038d582b5988f40873e380 287 SUPERFAMILY SSF109604 14 279 6.15E-56 T 28-03-2018 MKLM6_RS20210 7d154dde41038d582b5988f40873e380 287 Pfam PF08668 HDOD domain 19 211 1.5E-45 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD MKLM6_RS20210 7d154dde41038d582b5988f40873e380 287 Gene3D G3DSA:1.10.3210.10 1 272 3.0E-41 T 28-03-2018 MKLM6_RS04760 daea1097aa37baeaf26dca99bc0b0648 159 Gene3D G3DSA:3.40.30.10 1 156 2.7E-35 T 28-03-2018 MKLM6_RS04760 daea1097aa37baeaf26dca99bc0b0648 159 PIRSF PIRSF000239 3 159 1.9E-24 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MKLM6_RS04760 daea1097aa37baeaf26dca99bc0b0648 159 Pfam PF00578 AhpC/TSA family 7 135 7.8E-34 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MKLM6_RS04760 daea1097aa37baeaf26dca99bc0b0648 159 SUPERFAMILY SSF52833 3 156 2.06E-46 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS04575 86102c76189f42c2cf6c27cc90f5e93b 374 TIGRFAM TIGR02660 nifV_homocitr: homocitrate synthase 8 370 4.5E-157 T 28-03-2018 IPR013477 Homocitrate synthase NifV-type GO:0004410|GO:0051188 KEGG: 00300+2.3.3.14|KEGG: 00620+2.3.3.14|MetaCyc: PWY-3081|MetaCyc: PWY-7710 MKLM6_RS04575 86102c76189f42c2cf6c27cc90f5e93b 374 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 194 207 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MKLM6_RS04575 86102c76189f42c2cf6c27cc90f5e93b 374 Pfam PF00682 HMGL-like 8 264 3.7E-77 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MKLM6_RS04575 86102c76189f42c2cf6c27cc90f5e93b 374 SUPERFAMILY SSF51569 4 282 8.79E-80 T 28-03-2018 MKLM6_RS04575 86102c76189f42c2cf6c27cc90f5e93b 374 Gene3D G3DSA:3.20.20.70 1 323 2.5E-92 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS04575 86102c76189f42c2cf6c27cc90f5e93b 374 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 15 31 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MKLM6_RS18740 f84ee7cf4a4d5b0bf7112e706e77c7c2 339 Pfam PF09952 Transcriptional regulator, AbiEi antitoxin, Type IV TA system 192 332 1.4E-44 T 28-03-2018 IPR019238 Transcriptional regulator, AbiEi 2 antitoxin, Type IV TA system MKLM6_RS18740 f84ee7cf4a4d5b0bf7112e706e77c7c2 339 PIRSF PIRSF012611 12 336 3.2E-76 T 28-03-2018 IPR016600 Uncharacterised conserved protein UCP012611 MKLM6_RS21495 d0c30316783bfdd93f570ec78f431463 230 Gene3D G3DSA:3.40.50.300 2 159 9.8E-10 T 28-03-2018 MKLM6_RS21495 d0c30316783bfdd93f570ec78f431463 230 SUPERFAMILY SSF52540 9 207 1.56E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS21495 d0c30316783bfdd93f570ec78f431463 230 Gene3D G3DSA:1.10.8.60 162 227 7.4E-10 T 28-03-2018 MKLM6_RS21495 d0c30316783bfdd93f570ec78f431463 230 Pfam PF00308 Bacterial dnaA protein 12 205 2.9E-15 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA MKLM6_RS21495 d0c30316783bfdd93f570ec78f431463 230 TIGRFAM TIGR03420 DnaA_homol_Hda: DnaA regulatory inactivator Hda 2 226 5.8E-78 T 28-03-2018 IPR017788 DnaA regulatory inactivator Hda GO:0032297 MKLM6_RS01390 ce2c6bb45d7abd89215b926d8b5a9c20 467 SMART SM00387 353 464 1.2E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS01390 ce2c6bb45d7abd89215b926d8b5a9c20 467 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 356 457 1.1E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS01390 ce2c6bb45d7abd89215b926d8b5a9c20 467 SMART SM00388 244 309 3.1E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS01390 ce2c6bb45d7abd89215b926d8b5a9c20 467 Pfam PF00512 His Kinase A (phospho-acceptor) domain 246 308 3.9E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS01390 ce2c6bb45d7abd89215b926d8b5a9c20 467 Pfam PF08521 Two-component sensor kinase N-terminal 24 167 5.8E-8 T 28-03-2018 IPR013727 Two-component sensor kinase, N-terminal MKLM6_RS01390 ce2c6bb45d7abd89215b926d8b5a9c20 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 404 2.0E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS01390 ce2c6bb45d7abd89215b926d8b5a9c20 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 442 2.0E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS01390 ce2c6bb45d7abd89215b926d8b5a9c20 467 Gene3D G3DSA:1.10.287.130 234 305 4.6E-14 T 28-03-2018 MKLM6_RS01390 ce2c6bb45d7abd89215b926d8b5a9c20 467 SUPERFAMILY SSF47384 228 308 1.04E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS01390 ce2c6bb45d7abd89215b926d8b5a9c20 467 Gene3D G3DSA:1.20.5.1040 136 191 9.6E-8 T 28-03-2018 MKLM6_RS01390 ce2c6bb45d7abd89215b926d8b5a9c20 467 Gene3D G3DSA:1.20.5.1040 10 62 1.2E-11 T 28-03-2018 MKLM6_RS01390 ce2c6bb45d7abd89215b926d8b5a9c20 467 Gene3D G3DSA:3.30.565.10 314 465 1.6E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS01390 ce2c6bb45d7abd89215b926d8b5a9c20 467 SUPERFAMILY SSF55874 299 460 2.36E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS15250 eb074f978206b30fcace62169faf96e5 317 SUPERFAMILY SSF64182 5 315 6.54E-41 T 28-03-2018 MKLM6_RS18820 5e6b206bb2815a0e381e95d1de895a6d 350 Pfam PF10135 Rod binding protein 48 95 3.4E-15 T 28-03-2018 IPR019301 Flagellar protein FlgJ, N-terminal MKLM6_RS18820 5e6b206bb2815a0e381e95d1de895a6d 350 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 201 338 5.2E-20 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 MKLM6_RS18820 5e6b206bb2815a0e381e95d1de895a6d 350 Gene3D G3DSA:1.10.530.10 184 343 1.2E-33 T 28-03-2018 MKLM6_RS18820 5e6b206bb2815a0e381e95d1de895a6d 350 SMART SM00047 181 348 8.1E-32 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 MKLM6_RS18820 5e6b206bb2815a0e381e95d1de895a6d 350 PRINTS PR01002 Flagellar protein FlgJ signature 51 71 1.9E-13 T 28-03-2018 MKLM6_RS18820 5e6b206bb2815a0e381e95d1de895a6d 350 PRINTS PR01002 Flagellar protein FlgJ signature 72 94 1.9E-13 T 28-03-2018 MKLM6_RS18820 5e6b206bb2815a0e381e95d1de895a6d 350 PRINTS PR01002 Flagellar protein FlgJ signature 26 49 1.9E-13 T 28-03-2018 MKLM6_RS18820 5e6b206bb2815a0e381e95d1de895a6d 350 TIGRFAM TIGR02541 flagell_FlgJ: flagellar rod assembly protein/muramidase FlgJ 11 336 9.7E-95 T 28-03-2018 IPR013377 Peptidoglycan hydrolase FlgJ GO:0016798|GO:0044780 MKLM6_RS13290 9446c4f9a4121268e4d6d02e57d6c943 202 Hamap MF_00429 Na(+)-translocating NADH-quinone reductase subunit E [nqrE]. 1 202 28.713 T 28-03-2018 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 MKLM6_RS13290 9446c4f9a4121268e4d6d02e57d6c943 202 TIGRFAM TIGR01940 nqrE: NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit 3 201 9.7E-99 T 28-03-2018 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 MKLM6_RS13290 9446c4f9a4121268e4d6d02e57d6c943 202 Pfam PF02508 Rnf-Nqr subunit, membrane protein 4 200 1.1E-55 T 28-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 MKLM6_RS13290 9446c4f9a4121268e4d6d02e57d6c943 202 PIRSF PIRSF006102 1 202 2.6E-58 T 28-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 MKLM6_RS05050 a8e660dbe6b666fe157355e0c3c92446 206 Gene3D G3DSA:3.90.79.10 1 199 1.5E-39 T 28-03-2018 MKLM6_RS05050 a8e660dbe6b666fe157355e0c3c92446 206 Pfam PF00293 NUDIX domain 48 166 1.9E-13 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MKLM6_RS05050 a8e660dbe6b666fe157355e0c3c92446 206 ProSitePatterns PS00893 Nudix box signature. 87 108 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MKLM6_RS05050 a8e660dbe6b666fe157355e0c3c92446 206 SUPERFAMILY SSF55811 4 196 9.21E-42 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MKLM6_RS05050 a8e660dbe6b666fe157355e0c3c92446 206 TIGRFAM TIGR00052 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family 7 188 2.0E-50 T 28-03-2018 IPR004385 Nucleoside diphosphate pyrophosphatase GO:0016818|GO:0046872 Reactome: R-HSA-480985 MKLM6_RS11060 472c4d28b4ec76d5298730f5e719afd7 391 Gene3D G3DSA:2.40.50.100 281 352 3.0E-15 T 28-03-2018 MKLM6_RS11060 472c4d28b4ec76d5298730f5e719afd7 391 Gene3D G3DSA:3.40.50.300 1 238 2.0E-39 T 28-03-2018 MKLM6_RS11060 472c4d28b4ec76d5298730f5e719afd7 391 SMART SM00382 23 216 1.0E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS11060 472c4d28b4ec76d5298730f5e719afd7 391 Pfam PF03459 TOBE domain 296 351 1.6E-6 T 28-03-2018 IPR005116 Transport-associated OB, type 1 MKLM6_RS11060 472c4d28b4ec76d5298730f5e719afd7 391 SUPERFAMILY SSF50331 237 356 1.38E-18 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal MKLM6_RS11060 472c4d28b4ec76d5298730f5e719afd7 391 SUPERFAMILY SSF52540 6 231 3.39E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS11060 472c4d28b4ec76d5298730f5e719afd7 391 Pfam PF00005 ABC transporter 26 160 1.3E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS11060 472c4d28b4ec76d5298730f5e719afd7 391 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS11790 a914b3c17f50adc46933de43f0bd35a3 316 Gene3D G3DSA:3.90.420.10 29 276 1.4E-54 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 MKLM6_RS11790 a914b3c17f50adc46933de43f0bd35a3 316 Pfam PF00174 Oxidoreductase molybdopterin binding domain 95 247 2.0E-29 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 MKLM6_RS11790 a914b3c17f50adc46933de43f0bd35a3 316 Hamap MF_01206 Protein-methionine-sulfoxide reductase catalytic subunit MsrP [msrP]. 7 316 50.509 T 28-03-2018 IPR022867 Protein-methionine-sulfoxide reductase subunit MsrP GO:0016667|GO:0030091|GO:0043546|GO:0055114 MKLM6_RS11790 a914b3c17f50adc46933de43f0bd35a3 316 SUPERFAMILY SSF56524 63 312 3.01E-83 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 MKLM6_RS08155 b5a96334431351086b2e6ff0bd90473a 151 SUPERFAMILY SSF51182 38 144 2.81E-15 T 28-03-2018 IPR011051 RmlC-like cupin domain MKLM6_RS08155 b5a96334431351086b2e6ff0bd90473a 151 Gene3D G3DSA:2.60.120.10 35 150 1.5E-11 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS11475 88b43ce4f49cfac0d306ef16f0f718b6 553 Pfam PF02872 5'-nucleotidase, C-terminal domain 336 503 3.5E-32 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MKLM6_RS11475 88b43ce4f49cfac0d306ef16f0f718b6 553 Gene3D G3DSA:3.60.21.10 28 339 1.3E-45 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS11475 88b43ce4f49cfac0d306ef16f0f718b6 553 PRINTS PR01607 Apyrase family signature 242 265 1.5E-8 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MKLM6_RS11475 88b43ce4f49cfac0d306ef16f0f718b6 553 PRINTS PR01607 Apyrase family signature 392 415 1.5E-8 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MKLM6_RS11475 88b43ce4f49cfac0d306ef16f0f718b6 553 PRINTS PR01607 Apyrase family signature 223 240 1.5E-8 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MKLM6_RS11475 88b43ce4f49cfac0d306ef16f0f718b6 553 PRINTS PR01607 Apyrase family signature 477 496 1.5E-8 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MKLM6_RS11475 88b43ce4f49cfac0d306ef16f0f718b6 553 SUPERFAMILY SSF56300 34 326 8.16E-48 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS11475 88b43ce4f49cfac0d306ef16f0f718b6 553 SUPERFAMILY SSF55816 333 509 1.29E-36 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MKLM6_RS11475 88b43ce4f49cfac0d306ef16f0f718b6 553 Gene3D G3DSA:3.90.780.10 340 549 8.5E-39 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MKLM6_RS11475 88b43ce4f49cfac0d306ef16f0f718b6 553 Pfam PF00149 Calcineurin-like phosphoesterase 39 258 9.0E-10 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MKLM6_RS21585 32782cc0ba7f2a8c2ec020e951a874c6 550 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 318 541 5.2E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MKLM6_RS21585 32782cc0ba7f2a8c2ec020e951a874c6 550 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 282 542 3.4E-75 T 28-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 MKLM6_RS21585 32782cc0ba7f2a8c2ec020e951a874c6 550 SUPERFAMILY SSF161098 280 533 5.76E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MKLM6_RS21585 32782cc0ba7f2a8c2ec020e951a874c6 550 Gene3D G3DSA:1.10.3720.10 172 547 3.1E-39 T 28-03-2018 MKLM6_RS03535 796b72bd7f255c78e35a748d833d8ae4 439 SMART SM01086 331 425 8.3E-24 T 28-03-2018 IPR019489 Clp ATPase, C-terminal MKLM6_RS03535 796b72bd7f255c78e35a748d833d8ae4 439 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 1 439 43.334 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 MKLM6_RS03535 796b72bd7f255c78e35a748d833d8ae4 439 SMART SM00382 49 328 2.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS03535 796b72bd7f255c78e35a748d833d8ae4 439 Pfam PF07724 AAA domain (Cdc48 subfamily) 52 149 1.4E-8 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MKLM6_RS03535 796b72bd7f255c78e35a748d833d8ae4 439 Pfam PF07724 AAA domain (Cdc48 subfamily) 168 325 3.9E-42 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MKLM6_RS03535 796b72bd7f255c78e35a748d833d8ae4 439 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 4 439 1.9E-211 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 MKLM6_RS03535 796b72bd7f255c78e35a748d833d8ae4 439 Gene3D G3DSA:3.40.50.300 1 345 1.7E-51 T 28-03-2018 MKLM6_RS03535 796b72bd7f255c78e35a748d833d8ae4 439 Gene3D G3DSA:1.10.8.60 346 427 5.4E-31 T 28-03-2018 MKLM6_RS03535 796b72bd7f255c78e35a748d833d8ae4 439 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 331 401 3.2E-6 T 28-03-2018 IPR019489 Clp ATPase, C-terminal MKLM6_RS03535 796b72bd7f255c78e35a748d833d8ae4 439 SUPERFAMILY SSF52540 3 425 1.54E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS17375 f7832076e0f207ca140b565df60b1630 493 ProSitePatterns PS00090 Nitrogenases component 1 alpha and beta subunits signature 2. 152 166 - T 28-03-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 MKLM6_RS17375 f7832076e0f207ca140b565df60b1630 493 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 62 467 1.1E-111 T 28-03-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 MKLM6_RS17375 f7832076e0f207ca140b565df60b1630 493 TIGRFAM TIGR01862 N2-ase-Ialpha: nitrogenase component I, alpha chain 27 473 1.5E-201 T 28-03-2018 IPR010143 Nitrogenase component 1, alpha chain GO:0009399|GO:0016163|GO:0051536|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 MKLM6_RS17375 f7832076e0f207ca140b565df60b1630 493 Gene3D G3DSA:3.40.50.1980 1 74 2.6E-22 T 28-03-2018 MKLM6_RS17375 f7832076e0f207ca140b565df60b1630 493 Gene3D G3DSA:3.40.50.1980 210 311 3.4E-30 T 28-03-2018 MKLM6_RS17375 f7832076e0f207ca140b565df60b1630 493 Gene3D G3DSA:3.40.50.1980 75 209 2.2E-38 T 28-03-2018 MKLM6_RS17375 f7832076e0f207ca140b565df60b1630 493 Gene3D G3DSA:3.40.50.1980 389 479 4.7E-30 T 28-03-2018 MKLM6_RS17375 f7832076e0f207ca140b565df60b1630 493 Gene3D G3DSA:3.40.50.1980 312 388 9.6E-27 T 28-03-2018 MKLM6_RS17375 f7832076e0f207ca140b565df60b1630 493 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 81 88 - T 28-03-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 MKLM6_RS17375 f7832076e0f207ca140b565df60b1630 493 SUPERFAMILY SSF53807 7 479 2.78E-166 T 28-03-2018 MKLM6_RS17375 f7832076e0f207ca140b565df60b1630 493 TIGRFAM TIGR01282 nifD: nitrogenase molybdenum-iron protein alpha chain 12 479 2.6E-264 T 28-03-2018 IPR005972 Nitrogenase molybdenum-iron protein alpha chain GO:0009399|GO:0016163|GO:0016612|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 MKLM6_RS13570 2678b07a54f3e3ab450b932bf90d5a01 503 SUPERFAMILY SSF69705 3 134 1.12E-36 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 MKLM6_RS13570 2678b07a54f3e3ab450b932bf90d5a01 503 Gene3D G3DSA:3.30.300.20 207 280 3.1E-31 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta MKLM6_RS13570 2678b07a54f3e3ab450b932bf90d5a01 503 Gene3D G3DSA:2.40.50.140 137 206 7.1E-14 T 28-03-2018 MKLM6_RS13570 2678b07a54f3e3ab450b932bf90d5a01 503 Gene3D G3DSA:3.30.300.20 281 350 5.9E-13 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta MKLM6_RS13570 2678b07a54f3e3ab450b932bf90d5a01 503 Pfam PF00575 S1 RNA binding domain 140 203 1.3E-5 T 28-03-2018 IPR003029 S1 domain GO:0003676 MKLM6_RS13570 2678b07a54f3e3ab450b932bf90d5a01 503 SUPERFAMILY SSF50249 140 207 1.95E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS13570 2678b07a54f3e3ab450b932bf90d5a01 503 Pfam PF08529 NusA N-terminal domain 5 132 3.4E-35 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 MKLM6_RS13570 2678b07a54f3e3ab450b932bf90d5a01 503 Pfam PF14520 Helix-hairpin-helix domain 441 495 2.2E-7 T 28-03-2018 MKLM6_RS13570 2678b07a54f3e3ab450b932bf90d5a01 503 Gene3D G3DSA:3.30.1480.10 2 136 6.4E-40 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 MKLM6_RS13570 2678b07a54f3e3ab450b932bf90d5a01 503 Pfam PF13184 NusA-like KH domain 238 305 2.6E-26 T 28-03-2018 IPR025249 KH domain, NusA-like GO:0003723 MKLM6_RS13570 2678b07a54f3e3ab450b932bf90d5a01 503 SMART SM00316 141 208 1.8E-9 T 28-03-2018 IPR022967 RNA-binding domain, S1 MKLM6_RS13570 2678b07a54f3e3ab450b932bf90d5a01 503 SMART SM00322 238 298 11.0 T 28-03-2018 IPR004087 K Homology domain GO:0003676 MKLM6_RS13570 2678b07a54f3e3ab450b932bf90d5a01 503 SMART SM00322 309 372 0.0023 T 28-03-2018 IPR004087 K Homology domain GO:0003676 MKLM6_RS13570 2678b07a54f3e3ab450b932bf90d5a01 503 SUPERFAMILY SSF47794 363 424 1.73E-15 T 28-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 MKLM6_RS13570 2678b07a54f3e3ab450b932bf90d5a01 503 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 7 349 7.3E-122 T 28-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 MKLM6_RS13570 2678b07a54f3e3ab450b932bf90d5a01 503 SUPERFAMILY SSF54814 289 349 1.05E-14 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 MKLM6_RS13570 2678b07a54f3e3ab450b932bf90d5a01 503 SUPERFAMILY SSF47794 437 498 3.61E-13 T 28-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 MKLM6_RS13570 2678b07a54f3e3ab450b932bf90d5a01 503 Gene3D G3DSA:1.10.150.20 437 503 3.9E-14 T 28-03-2018 MKLM6_RS13570 2678b07a54f3e3ab450b932bf90d5a01 503 Gene3D G3DSA:1.10.150.20 360 429 1.2E-11 T 28-03-2018 MKLM6_RS13570 2678b07a54f3e3ab450b932bf90d5a01 503 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 448 497 5.1E-15 T 28-03-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication MKLM6_RS13570 2678b07a54f3e3ab450b932bf90d5a01 503 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 373 422 6.1E-18 T 28-03-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication MKLM6_RS13570 2678b07a54f3e3ab450b932bf90d5a01 503 SUPERFAMILY SSF54814 208 285 1.83E-28 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 MKLM6_RS13570 2678b07a54f3e3ab450b932bf90d5a01 503 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 3 418 28.651 T 28-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 MKLM6_RS15800 193879b0b0f6cc9e356bee7375586455 593 Pfam PF00005 ABC transporter 372 521 1.8E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS15800 193879b0b0f6cc9e356bee7375586455 593 SMART SM00382 380 568 1.8E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS15800 193879b0b0f6cc9e356bee7375586455 593 Gene3D G3DSA:3.40.50.300 344 588 1.1E-59 T 28-03-2018 MKLM6_RS15800 193879b0b0f6cc9e356bee7375586455 593 ProSitePatterns PS00211 ABC transporters family signature. 494 508 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS15800 193879b0b0f6cc9e356bee7375586455 593 SUPERFAMILY SSF90123 16 320 4.84E-13 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MKLM6_RS15800 193879b0b0f6cc9e356bee7375586455 593 Gene3D G3DSA:1.20.1560.10 3 343 3.6E-9 T 28-03-2018 MKLM6_RS15800 193879b0b0f6cc9e356bee7375586455 593 SUPERFAMILY SSF52540 346 578 3.84E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS17900 50273148c027896540368507d66c6dee 338 Pfam PF03793 PASTA domain 174 235 1.4E-9 T 28-03-2018 IPR005543 PASTA domain MKLM6_RS17900 50273148c027896540368507d66c6dee 338 Pfam PF03793 PASTA domain 240 301 2.7E-13 T 28-03-2018 IPR005543 PASTA domain MKLM6_RS17900 50273148c027896540368507d66c6dee 338 SMART SM00740 237 302 5.6E-12 T 28-03-2018 IPR005543 PASTA domain MKLM6_RS17900 50273148c027896540368507d66c6dee 338 SMART SM00740 169 236 5.4E-6 T 28-03-2018 IPR005543 PASTA domain MKLM6_RS17855 6ad19b8c14c237f44bcb3b50b01179c1 399 Pfam PF17482 Phage tail sheath C-terminal domain 280 384 1.4E-17 T 28-03-2018 IPR020287 Tail sheath protein, C-terminal domain MKLM6_RS17855 6ad19b8c14c237f44bcb3b50b01179c1 399 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 111 278 1.8E-16 T 28-03-2018 IPR035089 Tail sheath protein, subtilisin-like domain MKLM6_RS14905 e9f2920d627acbdb7946bc531841d90a 174 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 84 156 9.0E-9 T 28-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS14905 e9f2920d627acbdb7946bc531841d90a 174 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 102 150 - T 28-03-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS14905 e9f2920d627acbdb7946bc531841d90a 174 Gene3D G3DSA:2.60.40.420 21 170 1.4E-21 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS14905 e9f2920d627acbdb7946bc531841d90a 174 SUPERFAMILY SSF49503 63 168 4.97E-26 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS07485 844e8a802c507af69cec75a622267962 550 SMART SM00387 442 550 6.4E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS07485 844e8a802c507af69cec75a622267962 550 SMART SM00388 301 402 1.4E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS07485 844e8a802c507af69cec75a622267962 550 SMART SM00091 3 70 0.0023 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07485 844e8a802c507af69cec75a622267962 550 SMART SM00091 127 198 0.0031 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07485 844e8a802c507af69cec75a622267962 550 Pfam PF13426 PAS domain 15 70 0.0014 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07485 844e8a802c507af69cec75a622267962 550 PRINTS PR00344 Bacterial sensor protein C-terminal signature 497 507 6.7E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS07485 844e8a802c507af69cec75a622267962 550 PRINTS PR00344 Bacterial sensor protein C-terminal signature 479 493 6.7E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS07485 844e8a802c507af69cec75a622267962 550 PRINTS PR00344 Bacterial sensor protein C-terminal signature 510 528 6.7E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS07485 844e8a802c507af69cec75a622267962 550 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 547 6.7E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS07485 844e8a802c507af69cec75a622267962 550 Gene3D G3DSA:3.30.450.20 121 249 1.2E-19 T 28-03-2018 MKLM6_RS07485 844e8a802c507af69cec75a622267962 550 Gene3D G3DSA:3.30.565.10 400 549 8.2E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS07485 844e8a802c507af69cec75a622267962 550 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 445 547 5.3E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS07485 844e8a802c507af69cec75a622267962 550 SUPERFAMILY SSF47384 370 398 3.14E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS07485 844e8a802c507af69cec75a622267962 550 SUPERFAMILY SSF47384 293 336 3.14E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS07485 844e8a802c507af69cec75a622267962 550 Pfam PF12860 PAS fold 133 245 3.0E-6 T 28-03-2018 MKLM6_RS07485 844e8a802c507af69cec75a622267962 550 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 8 121 4.2E-11 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07485 844e8a802c507af69cec75a622267962 550 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 127 247 3.3E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07485 844e8a802c507af69cec75a622267962 550 SUPERFAMILY SSF55785 8 112 1.65E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07485 844e8a802c507af69cec75a622267962 550 Pfam PF00512 His Kinase A (phospho-acceptor) domain 302 399 6.3E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS07485 844e8a802c507af69cec75a622267962 550 Gene3D G3DSA:1.10.287.130 250 398 1.1E-10 T 28-03-2018 MKLM6_RS07485 844e8a802c507af69cec75a622267962 550 SUPERFAMILY SSF55785 139 249 1.65E-12 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07485 844e8a802c507af69cec75a622267962 550 Gene3D G3DSA:3.30.450.20 3 120 2.7E-9 T 28-03-2018 MKLM6_RS07485 844e8a802c507af69cec75a622267962 550 SUPERFAMILY SSF55874 392 548 2.49E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS08440 4e2cd92df4fb508d17a65794340393be 345 Pfam PF01548 Transposase 18 163 6.7E-22 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 MKLM6_RS08440 4e2cd92df4fb508d17a65794340393be 345 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 296 5.7E-19 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 MKLM6_RS06715 4e2cd92df4fb508d17a65794340393be 345 Pfam PF01548 Transposase 18 163 6.7E-22 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 MKLM6_RS06715 4e2cd92df4fb508d17a65794340393be 345 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 296 5.7E-19 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 MKLM6_RS18720 d70a5818f67118f369b5e1c3621078bc 981 Gene3D G3DSA:3.40.50.300 247 436 2.7E-25 T 28-03-2018 MKLM6_RS18720 d70a5818f67118f369b5e1c3621078bc 981 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 9 675 1.4E-132 T 28-03-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 MKLM6_RS18720 d70a5818f67118f369b5e1c3621078bc 981 Pfam PF04851 Type III restriction enzyme, res subunit 264 423 6.3E-22 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MKLM6_RS18720 d70a5818f67118f369b5e1c3621078bc 981 Gene3D G3DSA:3.40.50.300 490 653 0.0066 T 28-03-2018 MKLM6_RS18720 d70a5818f67118f369b5e1c3621078bc 981 SUPERFAMILY SSF52540 229 451 3.75E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS18720 d70a5818f67118f369b5e1c3621078bc 981 SMART SM00487 262 451 1.8E-15 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MKLM6_RS18720 d70a5818f67118f369b5e1c3621078bc 981 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 6 196 3.3E-18 T 28-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 MKLM6_RS14335 ba93395b727ed2e799bbd6a5bb33911f 211 Pfam PF01794 Ferric reductase like transmembrane component 51 163 1.2E-17 T 28-03-2018 IPR013130 Ferric reductase transmembrane component-like domain MKLM6_RS14335 ba93395b727ed2e799bbd6a5bb33911f 211 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 6 204 21.498 T 28-03-2018 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 MKLM6_RS10520 7e68be15dab8c5bf29c976318ac21bb8 300 SUPERFAMILY SSF53850 92 293 3.89E-40 T 28-03-2018 MKLM6_RS10520 7e68be15dab8c5bf29c976318ac21bb8 300 SUPERFAMILY SSF46785 1 112 3.06E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS10520 7e68be15dab8c5bf29c976318ac21bb8 300 Pfam PF03466 LysR substrate binding domain 91 292 4.2E-40 T 28-03-2018 IPR005119 LysR, substrate-binding MKLM6_RS10520 7e68be15dab8c5bf29c976318ac21bb8 300 Gene3D G3DSA:1.10.10.10 1 90 9.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS10520 7e68be15dab8c5bf29c976318ac21bb8 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 64 9.7E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS10520 7e68be15dab8c5bf29c976318ac21bb8 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS10520 7e68be15dab8c5bf29c976318ac21bb8 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS10520 7e68be15dab8c5bf29c976318ac21bb8 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS10520 7e68be15dab8c5bf29c976318ac21bb8 300 Gene3D G3DSA:3.40.190.10 91 181 3.6E-19 T 28-03-2018 MKLM6_RS10520 7e68be15dab8c5bf29c976318ac21bb8 300 Gene3D G3DSA:3.40.190.10 182 266 5.7E-19 T 28-03-2018 MKLM6_RS07380 4721ead213888b98c2550f35e021c3a0 866 SUPERFAMILY SSF55681 2 244 1.59E-108 T 28-03-2018 MKLM6_RS07380 4721ead213888b98c2550f35e021c3a0 866 PRINTS PR00980 Alanyl-tRNA synthetase signature 74 85 9.2E-33 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MKLM6_RS07380 4721ead213888b98c2550f35e021c3a0 866 PRINTS PR00980 Alanyl-tRNA synthetase signature 198 209 9.2E-33 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MKLM6_RS07380 4721ead213888b98c2550f35e021c3a0 866 PRINTS PR00980 Alanyl-tRNA synthetase signature 271 287 9.2E-33 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MKLM6_RS07380 4721ead213888b98c2550f35e021c3a0 866 PRINTS PR00980 Alanyl-tRNA synthetase signature 225 238 9.2E-33 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MKLM6_RS07380 4721ead213888b98c2550f35e021c3a0 866 PRINTS PR00980 Alanyl-tRNA synthetase signature 295 308 9.2E-33 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MKLM6_RS07380 4721ead213888b98c2550f35e021c3a0 866 Pfam PF01411 tRNA synthetases class II (A) 5 544 7.6E-220 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 MKLM6_RS07380 4721ead213888b98c2550f35e021c3a0 866 SMART SM00863 643 686 1.5E-21 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 MKLM6_RS07380 4721ead213888b98c2550f35e021c3a0 866 SUPERFAMILY SSF101353 245 453 2.62E-60 T 28-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 MKLM6_RS07380 4721ead213888b98c2550f35e021c3a0 866 Pfam PF02272 DHHA1 domain 722 858 1.8E-28 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 MKLM6_RS07380 4721ead213888b98c2550f35e021c3a0 866 Gene3D G3DSA:1.20.58.60 696 791 0.0015 T 28-03-2018 MKLM6_RS07380 4721ead213888b98c2550f35e021c3a0 866 Gene3D G3DSA:3.30.980.10 544 695 1.1E-44 T 28-03-2018 MKLM6_RS07380 4721ead213888b98c2550f35e021c3a0 866 SUPERFAMILY SSF55186 542 701 7.72E-50 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 MKLM6_RS07380 4721ead213888b98c2550f35e021c3a0 866 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 643 686 1.2E-17 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 MKLM6_RS07380 4721ead213888b98c2550f35e021c3a0 866 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 865 200.388 T 28-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 MKLM6_RS07380 4721ead213888b98c2550f35e021c3a0 866 SUPERFAMILY SSF50447 444 540 4.94E-17 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain MKLM6_RS07380 4721ead213888b98c2550f35e021c3a0 866 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 844 0.0 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MKLM6_RS07380 4721ead213888b98c2550f35e021c3a0 866 Gene3D G3DSA:3.30.930.10 1 241 4.2E-114 T 28-03-2018 MKLM6_RS16045 e3f586145ac79711497c7101ccbc1252 546 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 201 317 1.1E-20 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MKLM6_RS16045 e3f586145ac79711497c7101ccbc1252 546 SUPERFAMILY SSF52518 9 176 4.42E-40 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS16045 e3f586145ac79711497c7101ccbc1252 546 SUPERFAMILY SSF52518 360 544 1.61E-45 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS16045 e3f586145ac79711497c7101ccbc1252 546 PIRSF PIRSF036565 2 545 5.6E-154 T 28-03-2018 IPR012110 Thiamine pyrophosphate (TPP)-dependent enzyme GO:0016831 MKLM6_RS16045 e3f586145ac79711497c7101ccbc1252 546 Gene3D G3DSA:3.40.50.970 1 196 1.7E-46 T 28-03-2018 MKLM6_RS16045 e3f586145ac79711497c7101ccbc1252 546 Gene3D G3DSA:3.40.50.1220 197 342 9.0E-28 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MKLM6_RS16045 e3f586145ac79711497c7101ccbc1252 546 SUPERFAMILY SSF52467 166 337 1.4E-30 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MKLM6_RS16045 e3f586145ac79711497c7101ccbc1252 546 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 382 524 1.3E-23 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MKLM6_RS16045 e3f586145ac79711497c7101ccbc1252 546 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 172 4.3E-37 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MKLM6_RS16045 e3f586145ac79711497c7101ccbc1252 546 Gene3D G3DSA:3.40.50.970 343 540 1.2E-33 T 28-03-2018 MKLM6_RS18295 37d51d10e422a7071bde688ba746527c 536 Gene3D G3DSA:1.20.120.420 144 194 6.7E-15 T 28-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 MKLM6_RS18295 37d51d10e422a7071bde688ba746527c 536 SMART SM00028 179 211 0.13 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18295 37d51d10e422a7071bde688ba746527c 536 SMART SM00028 77 110 2.9E-6 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18295 37d51d10e422a7071bde688ba746527c 536 SMART SM00028 111 144 3.0E-5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18295 37d51d10e422a7071bde688ba746527c 536 SMART SM00028 43 76 0.46 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18295 37d51d10e422a7071bde688ba746527c 536 SMART SM00028 246 279 42.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18295 37d51d10e422a7071bde688ba746527c 536 SMART SM00028 212 245 1.7E-8 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18295 37d51d10e422a7071bde688ba746527c 536 SMART SM00028 145 178 0.017 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18295 37d51d10e422a7071bde688ba746527c 536 Gene3D G3DSA:1.20.58.280 121 143 1.8E-9 T 28-03-2018 MKLM6_RS18295 37d51d10e422a7071bde688ba746527c 536 Gene3D G3DSA:1.25.40.10 233 259 2.2E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18295 37d51d10e422a7071bde688ba746527c 536 SUPERFAMILY SSF48439 47 269 5.75E-38 T 28-03-2018 MKLM6_RS18295 37d51d10e422a7071bde688ba746527c 536 Gene3D G3DSA:2.60.120.620 338 536 2.5E-26 T 28-03-2018 MKLM6_RS18295 37d51d10e422a7071bde688ba746527c 536 Pfam PF13759 Putative 2OG-Fe(II) oxygenase 431 525 1.9E-23 T 28-03-2018 IPR012668 Conserved hypothetical protein CHP02466 MKLM6_RS18295 37d51d10e422a7071bde688ba746527c 536 Gene3D G3DSA:1.25.40.10 195 232 4.1E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18295 37d51d10e422a7071bde688ba746527c 536 SUPERFAMILY SSF51197 468 530 3.71E-5 T 28-03-2018 MKLM6_RS18295 37d51d10e422a7071bde688ba746527c 536 Pfam PF07719 Tetratricopeptide repeat 178 210 1.1E-5 T 28-03-2018 IPR013105 Tetratricopeptide repeat 2 MKLM6_RS18295 37d51d10e422a7071bde688ba746527c 536 Pfam PF13432 Tetratricopeptide repeat 16 75 2.2E-5 T 28-03-2018 MKLM6_RS18295 37d51d10e422a7071bde688ba746527c 536 Pfam PF13414 TPR repeat 84 124 2.0E-8 T 28-03-2018 MKLM6_RS18295 37d51d10e422a7071bde688ba746527c 536 Gene3D G3DSA:1.25.40.10 85 120 9.9E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18295 37d51d10e422a7071bde688ba746527c 536 Gene3D G3DSA:1.25.40.10 3 84 1.5E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18295 37d51d10e422a7071bde688ba746527c 536 Pfam PF13181 Tetratricopeptide repeat 146 177 0.01 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18295 37d51d10e422a7071bde688ba746527c 536 Pfam PF00515 Tetratricopeptide repeat 212 245 3.0E-9 T 28-03-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 MKLM6_RS18295 37d51d10e422a7071bde688ba746527c 536 Gene3D G3DSA:1.25.40.10 260 337 0.0027 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS17565 bc562d272fb9cd54a218ff8268656dbe 379 Gene3D G3DSA:2.60.40.420 245 340 5.8E-5 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS17565 bc562d272fb9cd54a218ff8268656dbe 379 SUPERFAMILY SSF49503 250 339 2.19E-8 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS17565 bc562d272fb9cd54a218ff8268656dbe 379 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 18 215 3.8E-42 T 28-03-2018 MKLM6_RS13765 711f4320a525188e0fd842cad5900ee5 400 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 276 378 6.3E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13765 711f4320a525188e0fd842cad5900ee5 400 Gene3D G3DSA:3.30.565.10 245 398 1.0E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13765 711f4320a525188e0fd842cad5900ee5 400 SUPERFAMILY SSF47384 166 235 7.26E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS13765 711f4320a525188e0fd842cad5900ee5 400 SMART SM00091 66 129 1.7E-6 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13765 711f4320a525188e0fd842cad5900ee5 400 Pfam PF13188 PAS domain 66 128 3.5E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13765 711f4320a525188e0fd842cad5900ee5 400 Gene3D G3DSA:1.10.287.130 168 234 2.3E-9 T 28-03-2018 MKLM6_RS13765 711f4320a525188e0fd842cad5900ee5 400 SMART SM00387 276 380 3.5E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13765 711f4320a525188e0fd842cad5900ee5 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 377 9.3E-22 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13765 711f4320a525188e0fd842cad5900ee5 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 311 325 9.3E-22 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13765 711f4320a525188e0fd842cad5900ee5 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 329 339 9.3E-22 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13765 711f4320a525188e0fd842cad5900ee5 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 340 358 9.3E-22 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13765 711f4320a525188e0fd842cad5900ee5 400 Pfam PF00512 His Kinase A (phospho-acceptor) domain 173 235 4.5E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS13765 711f4320a525188e0fd842cad5900ee5 400 Gene3D G3DSA:3.30.450.20 60 167 1.1E-11 T 28-03-2018 MKLM6_RS13765 711f4320a525188e0fd842cad5900ee5 400 SUPERFAMILY SSF55874 241 380 7.99E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13765 711f4320a525188e0fd842cad5900ee5 400 SUPERFAMILY SSF55785 53 146 2.09E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13765 711f4320a525188e0fd842cad5900ee5 400 SMART SM00388 172 238 4.5E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS09230 7390a30d8dd099bed16cd6d3a490fabd 598 Gene3D G3DSA:2.40.50.100 529 598 1.1E-17 T 28-03-2018 MKLM6_RS09230 7390a30d8dd099bed16cd6d3a490fabd 598 SUPERFAMILY SSF51569 5 303 8.06E-89 T 28-03-2018 MKLM6_RS09230 7390a30d8dd099bed16cd6d3a490fabd 598 SUPERFAMILY SSF89000 300 457 1.02E-47 T 28-03-2018 MKLM6_RS09230 7390a30d8dd099bed16cd6d3a490fabd 598 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 555 572 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MKLM6_RS09230 7390a30d8dd099bed16cd6d3a490fabd 598 SUPERFAMILY SSF51230 525 598 1.05E-19 T 28-03-2018 IPR011053 Single hybrid motif MKLM6_RS09230 7390a30d8dd099bed16cd6d3a490fabd 598 Gene3D G3DSA:3.20.20.70 1 287 3.6E-72 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS09230 7390a30d8dd099bed16cd6d3a490fabd 598 Pfam PF00364 Biotin-requiring enzyme 533 598 2.4E-15 T 28-03-2018 IPR000089 Biotin/lipoyl attachment MKLM6_RS09230 7390a30d8dd099bed16cd6d3a490fabd 598 TIGRFAM TIGR01108 oadA: oxaloacetate decarboxylase alpha subunit 10 595 4.4E-259 T 28-03-2018 IPR005776 Oxaloacetate decarboxylase, alpha subunit GO:0006814|GO:0008948 MKLM6_RS09230 7390a30d8dd099bed16cd6d3a490fabd 598 Pfam PF02436 Conserved carboxylase domain 295 497 2.0E-55 T 28-03-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 MKLM6_RS09230 7390a30d8dd099bed16cd6d3a490fabd 598 Gene3D G3DSA:1.10.10.60 402 456 7.0E-7 T 28-03-2018 MKLM6_RS09230 7390a30d8dd099bed16cd6d3a490fabd 598 Pfam PF00682 HMGL-like 10 273 5.6E-58 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MKLM6_RS03160 ba302351a3be0404ed9ed0a0878a5bc8 781 SMART SM00091 364 432 1.3E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03160 ba302351a3be0404ed9ed0a0878a5bc8 781 SMART SM00091 486 552 3.0E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03160 ba302351a3be0404ed9ed0a0878a5bc8 781 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 491 607 4.9E-20 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03160 ba302351a3be0404ed9ed0a0878a5bc8 781 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 360 485 2.0E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03160 ba302351a3be0404ed9ed0a0878a5bc8 781 SUPERFAMILY SSF55073 616 774 1.73E-50 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS03160 ba302351a3be0404ed9ed0a0878a5bc8 781 Pfam PF00990 Diguanylate cyclase, GGDEF domain 611 768 4.1E-50 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS03160 ba302351a3be0404ed9ed0a0878a5bc8 781 Pfam PF13426 PAS domain 376 477 1.2E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03160 ba302351a3be0404ed9ed0a0878a5bc8 781 Pfam PF13426 PAS domain 497 599 2.2E-19 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03160 ba302351a3be0404ed9ed0a0878a5bc8 781 Gene3D G3DSA:3.40.50.10600 488 604 6.9E-29 T 28-03-2018 MKLM6_RS03160 ba302351a3be0404ed9ed0a0878a5bc8 781 SMART SM00267 600 772 8.9E-69 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS03160 ba302351a3be0404ed9ed0a0878a5bc8 781 SUPERFAMILY SSF55785 356 476 1.48E-19 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03160 ba302351a3be0404ed9ed0a0878a5bc8 781 Gene3D G3DSA:3.30.450.20 351 487 2.9E-25 T 28-03-2018 MKLM6_RS03160 ba302351a3be0404ed9ed0a0878a5bc8 781 Pfam PF03924 CHASE domain 84 271 1.2E-62 T 28-03-2018 IPR006189 CHASE domain MKLM6_RS03160 ba302351a3be0404ed9ed0a0878a5bc8 781 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 607 770 1.4E-45 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS03160 ba302351a3be0404ed9ed0a0878a5bc8 781 Gene3D G3DSA:3.30.70.270 605 775 9.9E-64 T 28-03-2018 MKLM6_RS03160 ba302351a3be0404ed9ed0a0878a5bc8 781 SUPERFAMILY SSF55785 495 597 2.27E-31 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03160 ba302351a3be0404ed9ed0a0878a5bc8 781 SMART SM01079 81 273 1.0E-77 T 28-03-2018 IPR006189 CHASE domain MKLM6_RS03160 ba302351a3be0404ed9ed0a0878a5bc8 781 SMART SM00086 437 478 9.5 T 28-03-2018 IPR001610 PAC motif MKLM6_RS03160 ba302351a3be0404ed9ed0a0878a5bc8 781 SMART SM00086 558 600 8.5E-6 T 28-03-2018 IPR001610 PAC motif MKLM6_RS22285 0c1abbf1fafda76356ab8fa6e4dc49ea 1180 SUPERFAMILY SSF52540 222 304 3.41E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS22285 0c1abbf1fafda76356ab8fa6e4dc49ea 1180 SUPERFAMILY SSF52540 29 91 3.41E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS22285 0c1abbf1fafda76356ab8fa6e4dc49ea 1180 Gene3D G3DSA:3.40.50.300 36 327 1.1E-7 T 28-03-2018 MKLM6_RS22285 0c1abbf1fafda76356ab8fa6e4dc49ea 1180 Gene3D G3DSA:1.20.120.20 872 1099 0.0019 T 28-03-2018 MKLM6_RS18115 23f3bdc944ff8d53b3ed8b4c9ffd9e6e 220 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 16 216 2.5E-59 T 28-03-2018 MKLM6_RS18115 23f3bdc944ff8d53b3ed8b4c9ffd9e6e 220 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 11 220 36.894 T 28-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 MKLM6_RS18115 23f3bdc944ff8d53b3ed8b4c9ffd9e6e 220 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 12 218 1.1E-63 T 28-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 MKLM6_RS18115 23f3bdc944ff8d53b3ed8b4c9ffd9e6e 220 SUPERFAMILY SSF53335 14 218 2.67E-41 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS18115 23f3bdc944ff8d53b3ed8b4c9ffd9e6e 220 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 141 156 - T 28-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 MKLM6_RS18115 23f3bdc944ff8d53b3ed8b4c9ffd9e6e 220 Gene3D G3DSA:3.40.50.150 6 220 3.6E-33 T 28-03-2018 MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 SUPERFAMILY SSF54975 977 1076 3.14E-31 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 SUPERFAMILY SSF55073 543 701 7.06E-52 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 Pfam PF00989 PAS fold 414 524 7.5E-12 T 28-03-2018 IPR013767 PAS fold GO:0006355 MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 52 70 5.7E-5 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 33 49 5.7E-5 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 11 27 5.7E-5 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 SMART SM00086 487 527 2.1E-4 T 28-03-2018 IPR001610 PAC motif MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 SMART SM00091 410 476 2.2E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 SMART SM00052 709 956 2.3E-97 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 SMART SM01034 977 1069 1.2E-29 T 28-03-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 Pfam PF00990 Diguanylate cyclase, GGDEF domain 538 694 1.1E-50 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 Gene3D G3DSA:3.40.50.2300 8 197 2.8E-28 T 28-03-2018 MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 SUPERFAMILY SSF53822 10 365 9.76E-80 T 28-03-2018 IPR028082 Periplasmic binding protein-like I MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 Gene3D G3DSA:3.20.20.450 700 958 3.5E-93 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 536 695 6.9E-45 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 Gene3D G3DSA:3.40.50.2300 198 349 2.8E-12 T 28-03-2018 MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 SUPERFAMILY SSF55785 422 534 1.7E-25 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 SMART SM00267 527 699 6.5E-65 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 414 534 4.1E-23 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 Gene3D G3DSA:3.30.450.20 377 538 1.6E-22 T 28-03-2018 MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 Pfam PF04940 Sensors of blue-light using FAD 978 1067 4.4E-25 T 28-03-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 Pfam PF13458 Periplasmic binding protein 10 359 5.5E-62 T 28-03-2018 IPR028081 Leucine-binding protein domain MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 Pfam PF00563 EAL domain 717 951 7.9E-72 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 Gene3D G3DSA:3.30.70.270 539 699 1.5E-63 T 28-03-2018 MKLM6_RS14895 86f37fd9aca21d45121740ec0ab147d7 1113 SUPERFAMILY SSF141868 715 961 2.75E-83 T 28-03-2018 IPR001633 EAL domain MKLM6_RS08260 9779109844296eb3ded15c018a0cf6fe 1055 SUPERFAMILY SSF55874 26 127 5.64E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS08260 9779109844296eb3ded15c018a0cf6fe 1055 Gene3D G3DSA:3.30.565.10 18 331 3.2E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS10540 195037a33a82237071b9a4cf16f69f91 599 Gene3D G3DSA:3.90.1150.10 472 590 6.6E-39 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS10540 195037a33a82237071b9a4cf16f69f91 599 Gene3D G3DSA:3.40.640.10 223 471 8.3E-58 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS10540 195037a33a82237071b9a4cf16f69f91 599 Pfam PF00266 Aminotransferase class-V 215 583 1.3E-144 T 28-03-2018 IPR000192 Aminotransferase class V domain MKLM6_RS10540 195037a33a82237071b9a4cf16f69f91 599 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 196 590 8.6E-171 T 28-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 MKLM6_RS10540 195037a33a82237071b9a4cf16f69f91 599 SUPERFAMILY SSF53383 192 590 1.25E-122 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS11165 6f288682a6bd3174cb78952a8994989e 235 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 181 197 8.3E-11 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MKLM6_RS11165 6f288682a6bd3174cb78952a8994989e 235 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 197 212 8.3E-11 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MKLM6_RS11165 6f288682a6bd3174cb78952a8994989e 235 SUPERFAMILY SSF51206 12 147 1.7E-26 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like MKLM6_RS11165 6f288682a6bd3174cb78952a8994989e 235 Gene3D G3DSA:2.60.120.10 14 152 2.4E-19 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS11165 6f288682a6bd3174cb78952a8994989e 235 SMART SM00100 19 140 4.3E-14 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain MKLM6_RS11165 6f288682a6bd3174cb78952a8994989e 235 SUPERFAMILY SSF46785 154 231 3.87E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS11165 6f288682a6bd3174cb78952a8994989e 235 Gene3D G3DSA:1.10.10.10 153 232 8.8E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS11165 6f288682a6bd3174cb78952a8994989e 235 SMART SM00419 175 223 6.3E-13 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MKLM6_RS11165 6f288682a6bd3174cb78952a8994989e 235 Pfam PF13545 Crp-like helix-turn-helix domain 156 229 8.9E-17 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MKLM6_RS11165 6f288682a6bd3174cb78952a8994989e 235 Pfam PF00027 Cyclic nucleotide-binding domain 39 123 6.0E-14 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain MKLM6_RS21880 d0aeac44769e8ac6eb0ef6d637ddb3d3 312 Gene3D G3DSA:1.10.150.130 141 254 1.6E-12 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal MKLM6_RS21880 d0aeac44769e8ac6eb0ef6d637ddb3d3 312 Pfam PF00589 Phage integrase family 257 304 4.8E-5 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS21880 d0aeac44769e8ac6eb0ef6d637ddb3d3 312 SUPERFAMILY SSF56349 146 306 2.35E-17 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS21880 d0aeac44769e8ac6eb0ef6d637ddb3d3 312 Gene3D G3DSA:1.10.443.10 255 311 4.9E-6 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS15195 ff4bf57537c06bc30fbbaa51e51eeec0 259 SUPERFAMILY SSF50494 29 255 1.48E-32 T 28-03-2018 IPR009003 Peptidase S1, PA clan MKLM6_RS15195 ff4bf57537c06bc30fbbaa51e51eeec0 259 Gene3D G3DSA:2.40.10.10 24 132 3.3E-17 T 28-03-2018 MKLM6_RS15195 ff4bf57537c06bc30fbbaa51e51eeec0 259 Gene3D G3DSA:2.40.10.10 133 259 6.8E-20 T 28-03-2018 MKLM6_RS15195 ff4bf57537c06bc30fbbaa51e51eeec0 259 Pfam PF13365 Trypsin-like peptidase domain 58 220 4.9E-22 T 28-03-2018 MKLM6_RS22045 aa79c78903b0fcd58345d376835e96aa 594 SMART SM00327 416 591 1.3E-4 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS22045 aa79c78903b0fcd58345d376835e96aa 594 Gene3D G3DSA:3.40.50.410 410 582 3.5E-11 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS22045 aa79c78903b0fcd58345d376835e96aa 594 SUPERFAMILY SSF53300 418 563 6.33E-12 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS22045 aa79c78903b0fcd58345d376835e96aa 594 Pfam PF06213 Cobalamin biosynthesis protein CobT 7 268 2.0E-7 T 28-03-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 MKLM6_RS00015 d8ff2108b9332dda1e00c87de1859eeb 268 Gene3D G3DSA:3.40.50.1980 3 108 1.5E-19 T 28-03-2018 MKLM6_RS00015 d8ff2108b9332dda1e00c87de1859eeb 268 Pfam PF01497 Periplasmic binding protein 7 235 3.4E-37 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 MKLM6_RS00015 d8ff2108b9332dda1e00c87de1859eeb 268 Gene3D G3DSA:3.40.50.1980 109 260 2.1E-24 T 28-03-2018 MKLM6_RS00015 d8ff2108b9332dda1e00c87de1859eeb 268 SUPERFAMILY SSF53807 4 255 2.32E-44 T 28-03-2018 MKLM6_RS21810 553dd11c8ba4284f07bc703017fcad9b 687 SUPERFAMILY SSF52540 227 263 2.66E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS21810 553dd11c8ba4284f07bc703017fcad9b 687 SUPERFAMILY SSF52540 546 642 2.66E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS21810 553dd11c8ba4284f07bc703017fcad9b 687 SUPERFAMILY SSF52540 5 194 2.66E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS21810 553dd11c8ba4284f07bc703017fcad9b 687 SUPERFAMILY SSF52540 419 483 2.66E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS21810 553dd11c8ba4284f07bc703017fcad9b 687 Gene3D G3DSA:3.40.50.300 5 662 8.1E-17 T 28-03-2018 MKLM6_RS21810 553dd11c8ba4284f07bc703017fcad9b 687 Pfam PF13476 AAA domain 8 290 4.9E-14 T 28-03-2018 MKLM6_RS09060 1033d73aa450ee52ce4885af0136fb44 327 Hamap MF_00486 Methenyltetrahydromethanopterin cyclohydrolase [mch]. 1 327 146.537 T 28-03-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 MKLM6_RS09060 1033d73aa450ee52ce4885af0136fb44 327 Pfam PF02289 Cyclohydrolase (MCH) 6 325 1.8E-134 T 28-03-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 MKLM6_RS09060 1033d73aa450ee52ce4885af0136fb44 327 Gene3D G3DSA:3.10.340.11 6 64 4.9E-10 T 28-03-2018 MKLM6_RS09060 1033d73aa450ee52ce4885af0136fb44 327 Gene3D G3DSA:3.30.1030.10 65 125 9.7E-16 T 28-03-2018 MKLM6_RS09060 1033d73aa450ee52ce4885af0136fb44 327 Gene3D G3DSA:3.30.1030.10 131 327 9.8E-85 T 28-03-2018 MKLM6_RS09060 1033d73aa450ee52ce4885af0136fb44 327 TIGRFAM TIGR03120 one_C_mch: methenyltetrahydromethanopterin cyclohydrolase 6 326 2.2E-134 T 28-03-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 MKLM6_RS09060 1033d73aa450ee52ce4885af0136fb44 327 SUPERFAMILY SSF56199 5 326 8.63E-131 T 28-03-2018 MKLM6_RS16885 d0f01f020740dbbb52a7d65507bf83b8 142 Gene3D G3DSA:3.90.1180.10 1 142 6.6E-64 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MKLM6_RS16885 d0f01f020740dbbb52a7d65507bf83b8 142 PIRSF PIRSF002181 1 142 3.3E-51 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MKLM6_RS16885 d0f01f020740dbbb52a7d65507bf83b8 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 28.61 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MKLM6_RS16885 d0f01f020740dbbb52a7d65507bf83b8 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 141 2.3E-64 T 28-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS16885 d0f01f020740dbbb52a7d65507bf83b8 142 SUPERFAMILY SSF52161 1 140 4.58E-61 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MKLM6_RS16885 d0f01f020740dbbb52a7d65507bf83b8 142 Pfam PF00572 Ribosomal protein L13 15 138 9.4E-57 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MKLM6_RS10865 c8f4ec59225a7368bdb962717f6fede3 210 Gene3D G3DSA:3.40.50.300 1 206 1.6E-41 T 28-03-2018 MKLM6_RS10865 c8f4ec59225a7368bdb962717f6fede3 210 Pfam PF00005 ABC transporter 26 161 6.2E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS10865 c8f4ec59225a7368bdb962717f6fede3 210 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 9 204 9.3E-70 T 28-03-2018 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004|GO:0030288 MKLM6_RS10865 c8f4ec59225a7368bdb962717f6fede3 210 SUPERFAMILY SSF52540 8 204 7.93E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS10865 c8f4ec59225a7368bdb962717f6fede3 210 SMART SM00382 33 210 7.1E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS10865 c8f4ec59225a7368bdb962717f6fede3 210 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS02235 e9e0bafa51b5bd36763d72392e110b73 272 Gene3D G3DSA:3.60.110.10 2 270 1.2E-72 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS02235 e9e0bafa51b5bd36763d72392e110b73 272 Pfam PF00795 Carbon-nitrogen hydrolase 5 258 1.4E-54 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS02235 e9e0bafa51b5bd36763d72392e110b73 272 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 152 172 - T 28-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site MKLM6_RS02235 e9e0bafa51b5bd36763d72392e110b73 272 SUPERFAMILY SSF56317 4 267 1.57E-78 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS14620 ded9b53e91539067348e1ab35834560f 137 SUPERFAMILY SSF103196 13 133 7.06E-21 T 28-03-2018 MKLM6_RS14620 ded9b53e91539067348e1ab35834560f 137 Pfam PF03259 Roadblock/LC7 domain 19 106 4.2E-9 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain MKLM6_RS14620 ded9b53e91539067348e1ab35834560f 137 Gene3D G3DSA:3.30.450.30 6 136 4.4E-21 T 28-03-2018 MKLM6_RS14620 ded9b53e91539067348e1ab35834560f 137 SMART SM00960 18 107 3.2E-10 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain MKLM6_RS16200 9895953f02ac11234e1d50d7973a1ac2 188 Gene3D G3DSA:1.25.40.10 103 161 9.6E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS16200 9895953f02ac11234e1d50d7973a1ac2 188 Gene3D G3DSA:1.25.40.10 41 102 4.5E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS16200 9895953f02ac11234e1d50d7973a1ac2 188 SUPERFAMILY SSF48452 55 158 2.3E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS10970 51a90f41a661d803006526e9dae097dd 634 Gene3D G3DSA:3.30.450.40 173 347 5.6E-10 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS10970 51a90f41a661d803006526e9dae097dd 634 SUPERFAMILY SSF55781 196 342 8.29E-10 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS10970 51a90f41a661d803006526e9dae097dd 634 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 389 611 4.9E-29 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MKLM6_RS10970 51a90f41a661d803006526e9dae097dd 634 SUPERFAMILY SSF111369 400 550 8.89E-14 T 28-03-2018 MKLM6_RS10970 51a90f41a661d803006526e9dae097dd 634 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 392 574 1.2E-19 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MKLM6_RS10970 51a90f41a661d803006526e9dae097dd 634 Gene3D G3DSA:2.40.50.100 401 490 4.4E-10 T 28-03-2018 MKLM6_RS10970 51a90f41a661d803006526e9dae097dd 634 Gene3D G3DSA:2.40.50.100 491 580 1.3E-4 T 28-03-2018 MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 SUPERFAMILY SSF82714 704 789 4.71E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 SUPERFAMILY SSF82866 290 490 1.7E-49 T 28-03-2018 MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 Gene3D G3DSA:3.30.70.1430 558 654 4.1E-13 T 28-03-2018 MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 SUPERFAMILY SSF82693 790 835 1.49E-9 T 28-03-2018 MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 SUPERFAMILY SSF82693 655 703 1.49E-9 T 28-03-2018 MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 SUPERFAMILY SSF82693 40 133 9.94E-22 T 28-03-2018 MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 Gene3D G3DSA:3.30.2090.10 704 790 1.4E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 Gene3D G3DSA:3.30.2090.10 181 269 1.6E-13 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 SUPERFAMILY SSF82693 556 651 3.66E-14 T 28-03-2018 MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 5.9E-77 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 5.9E-77 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 5.9E-77 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 PRINTS PR00702 Acriflavin resistance protein family signature 543 560 5.9E-77 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 5.9E-77 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 5.9E-77 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 5.9E-77 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 5.9E-77 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 PRINTS PR00702 Acriflavin resistance protein family signature 607 621 5.9E-77 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 SUPERFAMILY SSF82866 813 1011 1.57E-43 T 28-03-2018 MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 SUPERFAMILY SSF82714 183 266 5.1E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 Gene3D G3DSA:1.20.1640.10 803 1023 5.2E-36 T 28-03-2018 MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 Gene3D G3DSA:1.20.1640.10 281 502 2.2E-49 T 28-03-2018 MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 Gene3D G3DSA:3.30.70.1430 40 142 1.9E-23 T 28-03-2018 MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 SUPERFAMILY SSF82693 137 182 4.36E-23 T 28-03-2018 MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 SUPERFAMILY SSF82693 268 324 4.36E-23 T 28-03-2018 MKLM6_RS16975 18647dcfb6c9ee0d0151534fd06a1bd2 1033 Pfam PF00873 AcrB/AcrD/AcrF family 4 1010 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS08940 0d653682087a502fcbc0e2a196ef6d35 82 Pfam PF10387 Protein of unknown function (DUF2442) 5 73 7.5E-19 T 28-03-2018 IPR018841 Protein of unknown function DUF2442 MKLM6_RS08940 0d653682087a502fcbc0e2a196ef6d35 82 SUPERFAMILY SSF143880 1 73 2.22E-21 T 28-03-2018 IPR018841 Protein of unknown function DUF2442 MKLM6_RS08940 0d653682087a502fcbc0e2a196ef6d35 82 Gene3D G3DSA:3.30.2020.10 1 77 1.4E-25 T 28-03-2018 IPR018841 Protein of unknown function DUF2442 MKLM6_RS05020 9facc43a33496982b12270776e784ade 666 Pfam PF01757 Acyltransferase family 21 367 3.4E-28 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 MKLM6_RS05020 9facc43a33496982b12270776e784ade 666 Gene3D G3DSA:3.40.50.1110 439 660 6.6E-8 T 28-03-2018 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 Gene3D G3DSA:3.40.50.1000 502 618 3.7E-16 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 SMART SM00831 14 87 2.7E-22 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 Pfam PF00690 Cation transporter/ATPase, N-terminus 16 82 6.0E-17 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 335 341 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 SUPERFAMILY SSF81665 234 327 4.05E-96 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 SUPERFAMILY SSF81665 644 845 4.05E-96 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 SUPERFAMILY SSF81665 13 125 4.05E-96 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 Gene3D G3DSA:3.40.1110.10 296 501 1.5E-34 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 23 843 8.5E-236 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 PRINTS PR01836 Magnesium-transporting ATPase signature 802 823 1.4E-41 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 PRINTS PR01836 Magnesium-transporting ATPase signature 263 282 1.4E-41 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 PRINTS PR01836 Magnesium-transporting ATPase signature 723 739 1.4E-41 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 PRINTS PR01836 Magnesium-transporting ATPase signature 753 774 1.4E-41 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 PRINTS PR01836 Magnesium-transporting ATPase signature 367 380 1.4E-41 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 PRINTS PR01836 Magnesium-transporting ATPase signature 653 668 1.4E-41 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 PRINTS PR01836 Magnesium-transporting ATPase signature 246 262 1.4E-41 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 PRINTS PR01836 Magnesium-transporting ATPase signature 703 716 1.4E-41 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 PRINTS PR01836 Magnesium-transporting ATPase signature 671 682 1.4E-41 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 Pfam PF00122 E1-E2 ATPase 125 313 1.2E-45 T 28-03-2018 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 Pfam PF00702 haloacid dehalogenase-like hydrolase 329 609 7.8E-22 T 28-03-2018 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 SUPERFAMILY SSF56784 331 351 9.07E-35 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 SUPERFAMILY SSF56784 451 694 9.07E-35 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 Gene3D G3DSA:1.20.1110.10 619 846 4.3E-34 T 28-03-2018 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 Gene3D G3DSA:2.70.150.10 23 234 5.1E-43 T 28-03-2018 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 SUPERFAMILY SSF81653 128 231 4.58E-28 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 Pfam PF00689 Cation transporting ATPase, C-terminus 678 839 1.2E-17 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 566 683 9.4E-24 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS14540 1f3fa00e86db7901af3c3e231762cd07 847 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 226 541 5.1E-31 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS11420 2eaa90c7cd0e42737e1645c35094acbe 406 SUPERFAMILY SSF56672 31 360 4.75E-48 T 28-03-2018 MKLM6_RS11420 2eaa90c7cd0e42737e1645c35094acbe 406 Gene3D G3DSA:3.30.70.270 116 291 9.2E-33 T 28-03-2018 MKLM6_RS11420 2eaa90c7cd0e42737e1645c35094acbe 406 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 144 162 1.1E-5 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MKLM6_RS11420 2eaa90c7cd0e42737e1645c35094acbe 406 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 220 233 1.1E-5 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MKLM6_RS11420 2eaa90c7cd0e42737e1645c35094acbe 406 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 76 89 1.1E-5 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MKLM6_RS11420 2eaa90c7cd0e42737e1645c35094acbe 406 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 202 215 1.1E-5 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MKLM6_RS11420 2eaa90c7cd0e42737e1645c35094acbe 406 Pfam PF08388 Group II intron, maturase-specific domain 304 374 5.8E-16 T 28-03-2018 IPR013597 Group II intron, maturase-specific MKLM6_RS11420 2eaa90c7cd0e42737e1645c35094acbe 406 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 81 291 3.0E-42 T 28-03-2018 IPR000477 Reverse transcriptase domain MKLM6_RS11420 2eaa90c7cd0e42737e1645c35094acbe 406 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 26 366 1.8E-119 T 28-03-2018 IPR030931 Group II intron reverse transcriptase/maturase MKLM6_RS01955 d3e9655d24f46eb997d22c4e1e0475b1 494 SUPERFAMILY SSF52540 9 243 1.4E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS01955 d3e9655d24f46eb997d22c4e1e0475b1 494 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 490 196.774 T 28-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 MKLM6_RS01955 d3e9655d24f46eb997d22c4e1e0475b1 494 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 258 437 3.6E-52 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 MKLM6_RS01955 d3e9655d24f46eb997d22c4e1e0475b1 494 SUPERFAMILY SSF52317 258 449 2.44E-37 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS01955 d3e9655d24f46eb997d22c4e1e0475b1 494 Gene3D G3DSA:3.40.50.300 7 232 8.0E-54 T 28-03-2018 MKLM6_RS01955 d3e9655d24f46eb997d22c4e1e0475b1 494 Gene3D G3DSA:3.40.50.880 233 393 8.4E-20 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS01955 d3e9655d24f46eb997d22c4e1e0475b1 494 Pfam PF13500 AAA domain 9 236 4.8E-22 T 28-03-2018 MKLM6_RS01955 d3e9655d24f46eb997d22c4e1e0475b1 494 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 10 480 7.9E-142 T 28-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 MKLM6_RS10140 60cbba1c11f03d40030e54682e9527c9 278 Gene3D G3DSA:1.10.155.10 4 77 2.0E-18 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MKLM6_RS10140 60cbba1c11f03d40030e54682e9527c9 278 SMART SM00138 12 276 6.0E-113 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS10140 60cbba1c11f03d40030e54682e9527c9 278 Pfam PF01739 CheR methyltransferase, SAM binding domain 79 271 8.1E-69 T 28-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal MKLM6_RS10140 60cbba1c11f03d40030e54682e9527c9 278 PRINTS PR00996 Glutamate methyltransferase family signature 34 47 5.5E-46 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS10140 60cbba1c11f03d40030e54682e9527c9 278 PRINTS PR00996 Glutamate methyltransferase family signature 145 161 5.5E-46 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS10140 60cbba1c11f03d40030e54682e9527c9 278 PRINTS PR00996 Glutamate methyltransferase family signature 235 258 5.5E-46 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS10140 60cbba1c11f03d40030e54682e9527c9 278 PRINTS PR00996 Glutamate methyltransferase family signature 112 132 5.5E-46 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS10140 60cbba1c11f03d40030e54682e9527c9 278 PRINTS PR00996 Glutamate methyltransferase family signature 72 84 5.5E-46 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS10140 60cbba1c11f03d40030e54682e9527c9 278 PRINTS PR00996 Glutamate methyltransferase family signature 216 230 5.5E-46 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS10140 60cbba1c11f03d40030e54682e9527c9 278 SUPERFAMILY SSF53335 79 275 1.15E-59 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS10140 60cbba1c11f03d40030e54682e9527c9 278 Gene3D G3DSA:3.40.50.150 78 276 6.1E-55 T 28-03-2018 MKLM6_RS10140 60cbba1c11f03d40030e54682e9527c9 278 SUPERFAMILY SSF47757 5 78 1.31E-16 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MKLM6_RS10140 60cbba1c11f03d40030e54682e9527c9 278 Pfam PF03705 CheR methyltransferase, all-alpha domain 13 65 9.5E-13 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MKLM6_RS10140 60cbba1c11f03d40030e54682e9527c9 278 PIRSF PIRSF000410 1 278 3.3E-107 T 28-03-2018 IPR026024 Chemotaxis protein methyltransferase CheR MKLM6_RS04435 0909afd1f82b94eafc5b766fc2584ba1 435 SUPERFAMILY SSF55920 174 433 3.27E-84 T 28-03-2018 IPR000994 Peptidase M24 MKLM6_RS04435 0909afd1f82b94eafc5b766fc2584ba1 435 Gene3D G3DSA:3.90.230.10 164 435 1.5E-85 T 28-03-2018 MKLM6_RS04435 0909afd1f82b94eafc5b766fc2584ba1 435 Pfam PF00557 Metallopeptidase family M24 180 412 4.2E-64 T 28-03-2018 IPR000994 Peptidase M24 MKLM6_RS04435 0909afd1f82b94eafc5b766fc2584ba1 435 SUPERFAMILY SSF53092 2 173 2.44E-52 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal MKLM6_RS04435 0909afd1f82b94eafc5b766fc2584ba1 435 Gene3D G3DSA:3.40.350.10 1 163 2.2E-51 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MKLM6_RS04435 0909afd1f82b94eafc5b766fc2584ba1 435 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 347 359 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site MKLM6_RS04435 0909afd1f82b94eafc5b766fc2584ba1 435 SMART SM01011 1 135 3.6E-59 T 28-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 MKLM6_RS04435 0909afd1f82b94eafc5b766fc2584ba1 435 Pfam PF05195 Aminopeptidase P, N-terminal domain 6 124 2.6E-36 T 28-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 MKLM6_RS17840 9d6d1345c33544bf38905a0312a04e34 1276 Gene3D G3DSA:1.25.40.10 441 534 0.0018 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS17840 9d6d1345c33544bf38905a0312a04e34 1276 Pfam PF12770 CHAT domain 975 1276 1.5E-66 T 28-03-2018 IPR024983 CHAT domain MKLM6_RS17840 9d6d1345c33544bf38905a0312a04e34 1276 Gene3D G3DSA:1.25.40.10 575 641 0.11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS17840 9d6d1345c33544bf38905a0312a04e34 1276 Gene3D G3DSA:1.25.40.10 50 420 2.0E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS17840 9d6d1345c33544bf38905a0312a04e34 1276 Gene3D G3DSA:3.40.50.1460 1035 1276 2.1E-31 T 28-03-2018 MKLM6_RS17840 9d6d1345c33544bf38905a0312a04e34 1276 Gene3D G3DSA:1.25.40.10 642 763 0.0038 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS17840 9d6d1345c33544bf38905a0312a04e34 1276 SMART SM00028 478 511 150.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS17840 9d6d1345c33544bf38905a0312a04e34 1276 SMART SM00028 726 759 29.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS17840 9d6d1345c33544bf38905a0312a04e34 1276 SMART SM00028 239 272 45.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS17840 9d6d1345c33544bf38905a0312a04e34 1276 SMART SM00028 81 114 7.7 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS17840 9d6d1345c33544bf38905a0312a04e34 1276 SUPERFAMILY SSF48452 621 659 7.8E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS17840 9d6d1345c33544bf38905a0312a04e34 1276 SUPERFAMILY SSF48452 82 116 7.8E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS17840 9d6d1345c33544bf38905a0312a04e34 1276 SUPERFAMILY SSF48452 700 755 7.8E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS17840 9d6d1345c33544bf38905a0312a04e34 1276 SUPERFAMILY SSF48452 484 511 7.8E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS17840 9d6d1345c33544bf38905a0312a04e34 1276 SUPERFAMILY SSF48452 420 508 6.64E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS14590 b0f6ae601f0d20c2459841042c757a6b 575 SMART SM01274 90 270 1.8E-79 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MKLM6_RS14590 b0f6ae601f0d20c2459841042c757a6b 575 PRINTS PR00072 Malic enzyme signature 417 433 3.7E-67 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MKLM6_RS14590 b0f6ae601f0d20c2459841042c757a6b 575 PRINTS PR00072 Malic enzyme signature 307 323 3.7E-67 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MKLM6_RS14590 b0f6ae601f0d20c2459841042c757a6b 575 PRINTS PR00072 Malic enzyme signature 96 120 3.7E-67 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MKLM6_RS14590 b0f6ae601f0d20c2459841042c757a6b 575 PRINTS PR00072 Malic enzyme signature 276 292 3.7E-67 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MKLM6_RS14590 b0f6ae601f0d20c2459841042c757a6b 575 PRINTS PR00072 Malic enzyme signature 192 214 3.7E-67 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MKLM6_RS14590 b0f6ae601f0d20c2459841042c757a6b 575 PRINTS PR00072 Malic enzyme signature 251 269 3.7E-67 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MKLM6_RS14590 b0f6ae601f0d20c2459841042c757a6b 575 PRINTS PR00072 Malic enzyme signature 156 185 3.7E-67 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MKLM6_RS14590 b0f6ae601f0d20c2459841042c757a6b 575 Pfam PF03949 Malic enzyme, NAD binding domain 280 539 1.9E-84 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MKLM6_RS14590 b0f6ae601f0d20c2459841042c757a6b 575 Gene3D G3DSA:3.40.50.10380 24 277 1.5E-97 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MKLM6_RS14590 b0f6ae601f0d20c2459841042c757a6b 575 Gene3D G3DSA:3.40.50.720 278 574 1.2E-90 T 28-03-2018 MKLM6_RS14590 b0f6ae601f0d20c2459841042c757a6b 575 PIRSF PIRSF000106 2 574 1.1E-197 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MKLM6_RS14590 b0f6ae601f0d20c2459841042c757a6b 575 SUPERFAMILY SSF53223 12 279 3.53E-94 T 28-03-2018 MKLM6_RS14590 b0f6ae601f0d20c2459841042c757a6b 575 Pfam PF00390 Malic enzyme, N-terminal domain 90 270 8.6E-65 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MKLM6_RS14590 b0f6ae601f0d20c2459841042c757a6b 575 SMART SM00919 280 540 2.4E-93 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MKLM6_RS14590 b0f6ae601f0d20c2459841042c757a6b 575 SUPERFAMILY SSF51735 280 573 5.99E-77 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS13995 b1acd0632942a74d449ebc3236e7eca1 497 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 461 8.6E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13995 b1acd0632942a74d449ebc3236e7eca1 497 PRINTS PR00344 Bacterial sensor protein C-terminal signature 467 480 8.6E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13995 b1acd0632942a74d449ebc3236e7eca1 497 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 438 8.6E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13995 b1acd0632942a74d449ebc3236e7eca1 497 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 424 8.6E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13995 b1acd0632942a74d449ebc3236e7eca1 497 Gene3D G3DSA:3.30.450.40 171 253 9.6E-4 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS13995 b1acd0632942a74d449ebc3236e7eca1 497 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 376 482 1.5E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13995 b1acd0632942a74d449ebc3236e7eca1 497 Pfam PF00512 His Kinase A (phospho-acceptor) domain 262 329 4.4E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS13995 b1acd0632942a74d449ebc3236e7eca1 497 SUPERFAMILY SSF55781 112 247 1.24E-6 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS13995 b1acd0632942a74d449ebc3236e7eca1 497 SUPERFAMILY SSF47384 255 330 1.18E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS13995 b1acd0632942a74d449ebc3236e7eca1 497 Pfam PF13493 Domain of unknown function (DUF4118) 8 114 2.7E-28 T 28-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain MKLM6_RS13995 b1acd0632942a74d449ebc3236e7eca1 497 SMART SM00388 261 329 8.9E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS13995 b1acd0632942a74d449ebc3236e7eca1 497 Gene3D G3DSA:1.10.287.130 254 323 1.8E-13 T 28-03-2018 MKLM6_RS13995 b1acd0632942a74d449ebc3236e7eca1 497 Gene3D G3DSA:3.30.565.10 324 483 6.3E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13995 b1acd0632942a74d449ebc3236e7eca1 497 Gene3D G3DSA:1.20.120.620 7 106 2.5E-24 T 28-03-2018 MKLM6_RS13995 b1acd0632942a74d449ebc3236e7eca1 497 SMART SM00387 373 483 1.5E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13995 b1acd0632942a74d449ebc3236e7eca1 497 SUPERFAMILY SSF55874 319 486 4.45E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13995 b1acd0632942a74d449ebc3236e7eca1 497 Gene3D G3DSA:3.30.450.40 110 170 3.6E-4 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS17545 dbc988af266dd6d608c51ac3e77adfa0 147 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 32 111 9.3E-7 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS17545 dbc988af266dd6d608c51ac3e77adfa0 147 SUPERFAMILY SSF46626 11 109 8.15E-12 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS17545 dbc988af266dd6d608c51ac3e77adfa0 147 Gene3D G3DSA:1.10.760.10 16 147 1.2E-12 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS09200 369fc3f4215c57924902a4de8b2ad6c0 640 Gene3D G3DSA:3.20.20.370 54 542 3.1E-50 T 28-03-2018 MKLM6_RS09200 369fc3f4215c57924902a4de8b2ad6c0 640 SUPERFAMILY SSF88713 201 326 1.39E-41 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MKLM6_RS09200 369fc3f4215c57924902a4de8b2ad6c0 640 SUPERFAMILY SSF88713 50 173 1.39E-41 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MKLM6_RS09200 369fc3f4215c57924902a4de8b2ad6c0 640 TIGRFAM TIGR03938 deacetyl_PgaB: poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB 31 634 8.8E-227 T 28-03-2018 IPR023854 Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB GO:0016810|GO:0042710 MKLM6_RS09200 369fc3f4215c57924902a4de8b2ad6c0 640 Pfam PF01522 Polysaccharide deacetylase 87 245 7.5E-31 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MKLM6_RS09200 369fc3f4215c57924902a4de8b2ad6c0 640 Pfam PF14883 Hypothetical glycosyl hydrolase family 13 295 616 1.9E-128 T 28-03-2018 IPR032772 Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, C-terminal MKLM6_RS16440 8f8ead11dfaedf0dde58ef3903ca1383 212 SUPERFAMILY SSF46894 139 209 6.46E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MKLM6_RS16440 8f8ead11dfaedf0dde58ef3903ca1383 212 SUPERFAMILY SSF52172 1 130 1.99E-34 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS16440 8f8ead11dfaedf0dde58ef3903ca1383 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 203 4.7E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS16440 8f8ead11dfaedf0dde58ef3903ca1383 212 SMART SM00448 2 115 6.9E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS16440 8f8ead11dfaedf0dde58ef3903ca1383 212 Gene3D G3DSA:1.10.10.10 126 211 5.4E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS16440 8f8ead11dfaedf0dde58ef3903ca1383 212 Pfam PF00072 Response regulator receiver domain 4 116 1.9E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS16440 8f8ead11dfaedf0dde58ef3903ca1383 212 SMART SM00421 146 203 4.9E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS16440 8f8ead11dfaedf0dde58ef3903ca1383 212 Gene3D G3DSA:3.40.50.2300 1 125 1.1E-36 T 28-03-2018 MKLM6_RS16440 8f8ead11dfaedf0dde58ef3903ca1383 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 1.1E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS16440 8f8ead11dfaedf0dde58ef3903ca1383 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 1.1E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS16440 8f8ead11dfaedf0dde58ef3903ca1383 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 1.1E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS21130 53e60937d673d8860e313fa3b0c3fe08 224 Hamap MF_01681 Enolase-phosphatase E1 [mtnC]. 1 222 42.953 T 28-03-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 MKLM6_RS21130 53e60937d673d8860e313fa3b0c3fe08 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 7.5E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MKLM6_RS21130 53e60937d673d8860e313fa3b0c3fe08 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 190 203 7.5E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MKLM6_RS21130 53e60937d673d8860e313fa3b0c3fe08 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 113 126 7.5E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MKLM6_RS21130 53e60937d673d8860e313fa3b0c3fe08 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 163 183 7.5E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MKLM6_RS21130 53e60937d673d8860e313fa3b0c3fe08 224 TIGRFAM TIGR01691 enolase-ppase: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 2 221 1.5E-82 T 28-03-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 MKLM6_RS21130 53e60937d673d8860e313fa3b0c3fe08 224 Gene3D G3DSA:3.40.50.1000 85 222 1.2E-14 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS21130 53e60937d673d8860e313fa3b0c3fe08 224 SUPERFAMILY SSF56784 1 206 2.36E-59 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS21130 53e60937d673d8860e313fa3b0c3fe08 224 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 116 195 4.0E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MKLM6_RS05380 1ccf43516bc68cd4470fad79dd3f9aaa 393 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 89 229 5.8E-19 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MKLM6_RS05380 1ccf43516bc68cd4470fad79dd3f9aaa 393 Gene3D G3DSA:3.40.47.10 7 235 5.2E-35 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS05380 1ccf43516bc68cd4470fad79dd3f9aaa 393 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 236 336 2.3E-26 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MKLM6_RS05380 1ccf43516bc68cd4470fad79dd3f9aaa 393 Gene3D G3DSA:3.40.47.10 241 393 1.9E-40 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS05380 1ccf43516bc68cd4470fad79dd3f9aaa 393 SUPERFAMILY SSF53901 7 228 5.0E-34 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS05380 1ccf43516bc68cd4470fad79dd3f9aaa 393 SUPERFAMILY SSF53901 204 392 2.66E-44 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS05380 1ccf43516bc68cd4470fad79dd3f9aaa 393 SMART SM00825 Beta-ketoacyl synthase 19 393 8.4E-8 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MKLM6_RS05380 1ccf43516bc68cd4470fad79dd3f9aaa 393 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 148 164 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site MKLM6_RS07110 322ae1677ad3a815f25c63c74bbd7a3e 431 SUPERFAMILY SSF52954 331 424 4.74E-20 T 28-03-2018 IPR004154 Anticodon-binding MKLM6_RS07110 322ae1677ad3a815f25c63c74bbd7a3e 431 Gene3D G3DSA:3.30.930.10 3 325 3.4E-72 T 28-03-2018 MKLM6_RS07110 322ae1677ad3a815f25c63c74bbd7a3e 431 PIRSF PIRSF001549 4 425 1.3E-118 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 MKLM6_RS07110 322ae1677ad3a815f25c63c74bbd7a3e 431 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 9 410 4.3E-151 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 MKLM6_RS07110 322ae1677ad3a815f25c63c74bbd7a3e 431 Gene3D G3DSA:3.40.50.800 326 426 1.3E-12 T 28-03-2018 IPR004154 Anticodon-binding MKLM6_RS07110 322ae1677ad3a815f25c63c74bbd7a3e 431 SUPERFAMILY SSF55681 8 320 3.19E-102 T 28-03-2018 MKLM6_RS07110 322ae1677ad3a815f25c63c74bbd7a3e 431 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 6 424 32.862 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 MKLM6_RS07110 322ae1677ad3a815f25c63c74bbd7a3e 431 Pfam PF13393 Histidyl-tRNA synthetase 13 315 1.7E-45 T 28-03-2018 MKLM6_RS07110 322ae1677ad3a815f25c63c74bbd7a3e 431 Pfam PF03129 Anticodon binding domain 333 424 1.5E-9 T 28-03-2018 IPR004154 Anticodon-binding MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 SUPERFAMILY SSF55785 368 482 1.5E-21 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 SUPERFAMILY SSF55073 754 912 5.02E-48 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 SMART SM00091 492 560 210.0 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 SMART SM00091 623 689 7.5E-4 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 SMART SM00091 362 430 4.3E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 Pfam PF08447 PAS fold 515 602 6.4E-10 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 Pfam PF08447 PAS fold 385 473 2.3E-22 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 SUPERFAMILY SSF141868 927 1173 7.85E-81 T 28-03-2018 IPR001633 EAL domain MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 SUPERFAMILY SSF55785 477 606 1.47E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 Pfam PF00563 EAL domain 927 1162 5.8E-67 T 28-03-2018 IPR001633 EAL domain MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 SMART SM01079 72 268 5.5E-76 T 28-03-2018 IPR006189 CHASE domain MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 SMART SM00086 694 738 14.0 T 28-03-2018 IPR001610 PAC motif MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 SMART SM00086 566 608 1.2E-4 T 28-03-2018 IPR001610 PAC motif MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 SMART SM00086 437 480 1.6E-9 T 28-03-2018 IPR001610 PAC motif MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 Pfam PF03924 CHASE domain 75 266 1.9E-63 T 28-03-2018 IPR006189 CHASE domain MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 SMART SM00052 921 1167 1.9E-94 T 28-03-2018 IPR001633 EAL domain MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 745 910 1.4E-42 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 Pfam PF08448 PAS fold 634 736 1.3E-13 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 SUPERFAMILY SSF55785 605 736 1.22E-19 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 Pfam PF13682 Chemoreceptor zinc-binding domain 1203 1265 1.5E-8 T 28-03-2018 IPR025991 Chemoreceptor zinc-binding domain MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 Pfam PF00990 Diguanylate cyclase, GGDEF domain 749 907 8.8E-48 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 Gene3D G3DSA:3.30.70.270 744 910 8.2E-57 T 28-03-2018 MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 SMART SM00267 738 911 4.7E-60 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 Gene3D G3DSA:3.30.450.20 621 743 1.0E-20 T 28-03-2018 MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 Gene3D G3DSA:3.30.450.20 330 494 2.7E-35 T 28-03-2018 MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 Gene3D G3DSA:3.30.450.20 495 620 2.5E-21 T 28-03-2018 MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 Gene3D G3DSA:3.20.20.450 911 1170 2.2E-86 T 28-03-2018 IPR001633 EAL domain MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 501 615 7.9E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 359 487 3.8E-12 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17495 a2e88c1376cec728829361a5c00e66ad 1301 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 622 744 4.3E-11 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11170 62d6e627ad9458afb731e323dca5b870 335 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 6 334 46.398 T 28-03-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MKLM6_RS11170 62d6e627ad9458afb731e323dca5b870 335 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 68 94 1.2E-69 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MKLM6_RS11170 62d6e627ad9458afb731e323dca5b870 335 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 149 172 1.2E-69 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MKLM6_RS11170 62d6e627ad9458afb731e323dca5b870 335 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 308 333 1.2E-69 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MKLM6_RS11170 62d6e627ad9458afb731e323dca5b870 335 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 206 233 1.2E-69 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MKLM6_RS11170 62d6e627ad9458afb731e323dca5b870 335 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 31 58 1.2E-69 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MKLM6_RS11170 62d6e627ad9458afb731e323dca5b870 335 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 180 203 1.2E-69 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MKLM6_RS11170 62d6e627ad9458afb731e323dca5b870 335 PIRSF PIRSF500210 2 335 2.2E-124 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MKLM6_RS11170 62d6e627ad9458afb731e323dca5b870 335 PIRSF PIRSF000904 2 335 4.0E-123 T 28-03-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MKLM6_RS11170 62d6e627ad9458afb731e323dca5b870 335 Gene3D G3DSA:3.40.190.80 197 335 2.1E-53 T 28-03-2018 MKLM6_RS11170 62d6e627ad9458afb731e323dca5b870 335 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 7 194 1.3E-66 T 28-03-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MKLM6_RS11170 62d6e627ad9458afb731e323dca5b870 335 SUPERFAMILY SSF56655 3 332 1.62E-114 T 28-03-2018 MKLM6_RS11170 62d6e627ad9458afb731e323dca5b870 335 Gene3D G3DSA:3.30.540.10 5 196 9.1E-61 T 28-03-2018 MKLM6_RS02520 d0232a1a259b44ea648ac590188c6f2e 670 Gene3D G3DSA:2.60.500.10 168 254 1.4E-15 T 28-03-2018 MKLM6_RS02520 d0232a1a259b44ea648ac590188c6f2e 670 Gene3D G3DSA:2.40.128.130 303 670 1.7E-39 T 28-03-2018 MKLM6_RS02520 d0232a1a259b44ea648ac590188c6f2e 670 Pfam PF03797 Autotransporter beta-domain 392 649 1.1E-42 T 28-03-2018 IPR005546 Autotransporter beta-domain MKLM6_RS02520 d0232a1a259b44ea648ac590188c6f2e 670 SMART SM00869 388 659 4.0E-22 T 28-03-2018 IPR005546 Autotransporter beta-domain MKLM6_RS02520 d0232a1a259b44ea648ac590188c6f2e 670 SUPERFAMILY SSF103515 329 343 1.09E-34 T 28-03-2018 IPR005546 Autotransporter beta-domain MKLM6_RS02520 d0232a1a259b44ea648ac590188c6f2e 670 SUPERFAMILY SSF103515 381 670 1.09E-34 T 28-03-2018 IPR005546 Autotransporter beta-domain MKLM6_RS15820 28cb52515dcd0671ab3ef66c0eda211a 347 SMART SM00858 289 347 1.7E-9 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 MKLM6_RS15820 28cb52515dcd0671ab3ef66c0eda211a 347 Gene3D G3DSA:3.90.1210.10 277 346 5.1E-26 T 28-03-2018 MKLM6_RS15820 28cb52515dcd0671ab3ef66c0eda211a 347 Pfam PF03102 NeuB family 34 274 2.3E-89 T 28-03-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 MKLM6_RS15820 28cb52515dcd0671ab3ef66c0eda211a 347 SUPERFAMILY SSF51269 285 346 2.49E-19 T 28-03-2018 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal Reactome: R-HSA-4085001 MKLM6_RS15820 28cb52515dcd0671ab3ef66c0eda211a 347 SUPERFAMILY SSF51569 1 299 6.72E-91 T 28-03-2018 MKLM6_RS15820 28cb52515dcd0671ab3ef66c0eda211a 347 Gene3D G3DSA:3.20.20.70 1 276 5.9E-90 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS15820 28cb52515dcd0671ab3ef66c0eda211a 347 TIGRFAM TIGR03586 PseI: pseudaminic acid synthase 14 341 2.4E-154 T 28-03-2018 IPR020030 Pseudaminic acid biosynthesis, PseI KEGG: 00520+2.5.1.97|MetaCyc: PWY-6143 MKLM6_RS15820 28cb52515dcd0671ab3ef66c0eda211a 347 Pfam PF08666 SAF domain 290 346 1.6E-11 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 MKLM6_RS19780 f85fe001fbf1351810efe75e67d8abe5 78 TIGRFAM TIGR02450 TIGR02450: tryptophan-rich conserved hypothetical protein 15 77 3.9E-10 T 28-03-2018 IPR012663 Conserved hypothetical protein CHP02450, tryptophan-rich MKLM6_RS19780 f85fe001fbf1351810efe75e67d8abe5 78 Pfam PF09493 Tryptophan-rich protein (DUF2389) 17 77 1.0E-16 T 28-03-2018 IPR012663 Conserved hypothetical protein CHP02450, tryptophan-rich MKLM6_RS01090 402e4b27efb77f4cd1d8835cad7d854c 972 SUPERFAMILY SSF51445 470 716 4.88E-5 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily MKLM6_RS01090 402e4b27efb77f4cd1d8835cad7d854c 972 Gene3D G3DSA:2.60.120.260 178 401 0.51 T 28-03-2018 IPR008979 Galactose-binding domain-like MKLM6_RS01090 402e4b27efb77f4cd1d8835cad7d854c 972 Gene3D G3DSA:2.60.120.260 27 159 0.026 T 28-03-2018 IPR008979 Galactose-binding domain-like MKLM6_RS01090 402e4b27efb77f4cd1d8835cad7d854c 972 Gene3D G3DSA:3.20.20.80 407 739 3.6E-6 T 28-03-2018 MKLM6_RS01090 402e4b27efb77f4cd1d8835cad7d854c 972 Pfam PF02638 Glycosyl hydrolase-like 10 463 701 1.6E-11 T 28-03-2018 IPR003790 Glycosyl hydrolase-like 10 MKLM6_RS10550 7d18ab19ef07e10f4b271038c77e9528 193 Pfam PF03861 ANTAR domain 137 185 1.6E-16 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 MKLM6_RS10550 7d18ab19ef07e10f4b271038c77e9528 193 SMART SM01012 130 185 1.5E-19 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 MKLM6_RS10550 7d18ab19ef07e10f4b271038c77e9528 193 Gene3D G3DSA:1.10.10.10 136 186 1.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS10550 7d18ab19ef07e10f4b271038c77e9528 193 PIRSF PIRSF036382 1 192 3.1E-49 T 28-03-2018 IPR008327 Signal transduction response regulator, antiterminator MKLM6_RS10550 7d18ab19ef07e10f4b271038c77e9528 193 Gene3D G3DSA:3.40.50.2300 1 135 5.0E-15 T 28-03-2018 MKLM6_RS10550 7d18ab19ef07e10f4b271038c77e9528 193 Pfam PF00072 Response regulator receiver domain 7 114 1.8E-9 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS10550 7d18ab19ef07e10f4b271038c77e9528 193 SUPERFAMILY SSF52172 4 185 6.69E-40 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS18450 03d99d9b08c39aa8233e0893e3d8c268 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 145 6.8E-15 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MKLM6_RS18450 03d99d9b08c39aa8233e0893e3d8c268 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 8.5E-18 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MKLM6_RS18450 03d99d9b08c39aa8233e0893e3d8c268 396 Gene3D G3DSA:3.40.50.300 1 74 2.2E-12 T 28-03-2018 MKLM6_RS18450 03d99d9b08c39aa8233e0893e3d8c268 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 7.0E-226 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MKLM6_RS18450 03d99d9b08c39aa8233e0893e3d8c268 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.8E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18450 03d99d9b08c39aa8233e0893e3d8c268 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 3.8E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18450 03d99d9b08c39aa8233e0893e3d8c268 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.8E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18450 03d99d9b08c39aa8233e0893e3d8c268 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 3.8E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18450 03d99d9b08c39aa8233e0893e3d8c268 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.8E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18450 03d99d9b08c39aa8233e0893e3d8c268 396 SUPERFAMILY SSF52540 6 221 4.5E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS18450 03d99d9b08c39aa8233e0893e3d8c268 396 Gene3D G3DSA:2.40.30.10 302 395 3.6E-33 T 28-03-2018 MKLM6_RS18450 03d99d9b08c39aa8233e0893e3d8c268 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 59.86 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MKLM6_RS18450 03d99d9b08c39aa8233e0893e3d8c268 396 SUPERFAMILY SSF50465 304 396 1.78E-36 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MKLM6_RS18450 03d99d9b08c39aa8233e0893e3d8c268 396 Gene3D G3DSA:2.40.30.10 208 298 9.0E-31 T 28-03-2018 MKLM6_RS18450 03d99d9b08c39aa8233e0893e3d8c268 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 2.8E-34 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal MKLM6_RS18450 03d99d9b08c39aa8233e0893e3d8c268 396 SUPERFAMILY SSF50447 207 303 4.12E-30 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain MKLM6_RS18450 03d99d9b08c39aa8233e0893e3d8c268 396 Gene3D G3DSA:3.40.50.300 75 205 7.8E-29 T 28-03-2018 MKLM6_RS18450 03d99d9b08c39aa8233e0893e3d8c268 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 5.9E-59 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18450 03d99d9b08c39aa8233e0893e3d8c268 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site MKLM6_RS05200 0c7827711b83e5b2d177307d42bd8896 446 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 6 441 2.5E-194 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS05200 0c7827711b83e5b2d177307d42bd8896 446 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 253 1.8E-17 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS05200 0c7827711b83e5b2d177307d42bd8896 446 SUPERFAMILY SSF53738 257 363 1.41E-29 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS05200 0c7827711b83e5b2d177307d42bd8896 446 Gene3D G3DSA:3.40.120.10 2 153 1.2E-46 T 28-03-2018 MKLM6_RS05200 0c7827711b83e5b2d177307d42bd8896 446 SUPERFAMILY SSF53738 3 180 3.14E-47 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS05200 0c7827711b83e5b2d177307d42bd8896 446 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 95 104 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS05200 0c7827711b83e5b2d177307d42bd8896 446 SUPERFAMILY SSF53738 155 256 2.28E-29 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS05200 0c7827711b83e5b2d177307d42bd8896 446 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 2 443 47.686 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS05200 0c7827711b83e5b2d177307d42bd8896 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 3.8E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS05200 0c7827711b83e5b2d177307d42bd8896 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 3.8E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS05200 0c7827711b83e5b2d177307d42bd8896 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 3.8E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS05200 0c7827711b83e5b2d177307d42bd8896 446 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 372 438 7.2E-15 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS05200 0c7827711b83e5b2d177307d42bd8896 446 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 368 6.7E-31 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS05200 0c7827711b83e5b2d177307d42bd8896 446 Gene3D G3DSA:3.30.310.50 373 445 8.0E-21 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS05200 0c7827711b83e5b2d177307d42bd8896 446 Gene3D G3DSA:3.40.120.10 154 266 3.8E-30 T 28-03-2018 MKLM6_RS05200 0c7827711b83e5b2d177307d42bd8896 446 SUPERFAMILY SSF55957 356 444 5.36E-23 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS05200 0c7827711b83e5b2d177307d42bd8896 446 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 4 133 6.2E-42 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS05200 0c7827711b83e5b2d177307d42bd8896 446 Gene3D G3DSA:3.40.120.10 267 372 2.2E-28 T 28-03-2018 MKLM6_RS12515 d6b86e4f4e268eabb5e9e71dcd91eeb1 573 Gene3D G3DSA:3.40.1130.10 33 285 6.4E-35 T 28-03-2018 MKLM6_RS12515 d6b86e4f4e268eabb5e9e71dcd91eeb1 573 SMART SM00563 80 198 5.8E-8 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MKLM6_RS12515 d6b86e4f4e268eabb5e9e71dcd91eeb1 573 SUPERFAMILY SSF69593 41 264 5.75E-13 T 28-03-2018 MKLM6_RS12515 d6b86e4f4e268eabb5e9e71dcd91eeb1 573 SUPERFAMILY SSF55729 307 475 1.17E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS12515 d6b86e4f4e268eabb5e9e71dcd91eeb1 573 Gene3D G3DSA:3.40.630.30 309 514 1.4E-23 T 28-03-2018 MKLM6_RS12515 d6b86e4f4e268eabb5e9e71dcd91eeb1 573 Pfam PF13444 Acetyltransferase (GNAT) domain 325 425 3.8E-21 T 28-03-2018 MKLM6_RS12515 d6b86e4f4e268eabb5e9e71dcd91eeb1 573 Pfam PF01553 Acyltransferase 72 195 2.8E-10 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MKLM6_RS21580 f774d5dbd3fb182381a8be78ea2f47c7 277 ProSitePatterns PS00211 ABC transporters family signature. 174 188 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS21580 f774d5dbd3fb182381a8be78ea2f47c7 277 Gene3D G3DSA:3.40.50.300 16 275 3.2E-62 T 28-03-2018 MKLM6_RS21580 f774d5dbd3fb182381a8be78ea2f47c7 277 Pfam PF00005 ABC transporter 46 201 8.1E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS21580 f774d5dbd3fb182381a8be78ea2f47c7 277 SUPERFAMILY SSF52540 30 264 2.89E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS21580 f774d5dbd3fb182381a8be78ea2f47c7 277 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 31 277 9.1E-127 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 MKLM6_RS21580 f774d5dbd3fb182381a8be78ea2f47c7 277 SMART SM00382 55 258 1.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 517 679 1.9E-44 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 Pfam PF00990 Diguanylate cyclase, GGDEF domain 520 677 1.2E-52 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 Gene3D G3DSA:3.30.450.20 395 515 9.3E-23 T 28-03-2018 MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 SUPERFAMILY SSF55785 130 255 4.36E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 SUPERFAMILY SSF55785 254 385 6.81E-23 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 Gene3D G3DSA:3.30.450.20 146 263 2.8E-25 T 28-03-2018 MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 SMART SM00448 5 116 1.7E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 SMART SM00086 344 387 1.3E-10 T 28-03-2018 IPR001610 PAC motif MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 SMART SM00086 215 257 3.0E-4 T 28-03-2018 IPR001610 PAC motif MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 SMART SM00086 467 509 0.0015 T 28-03-2018 IPR001610 PAC motif MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 SMART SM00052 691 937 1.2E-115 T 28-03-2018 IPR001633 EAL domain MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 Pfam PF00072 Response regulator receiver domain 7 116 1.6E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 Gene3D G3DSA:3.20.20.450 688 941 6.7E-99 T 28-03-2018 IPR001633 EAL domain MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 392 515 1.5E-19 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 138 264 1.0E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 266 394 2.3E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 SMART SM00267 509 681 2.9E-69 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 Pfam PF08448 PAS fold 155 259 1.1E-10 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 SUPERFAMILY SSF55073 525 683 2.38E-52 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 SUPERFAMILY SSF141868 696 941 9.02E-87 T 28-03-2018 IPR001633 EAL domain MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 Gene3D G3DSA:3.30.70.270 516 687 7.8E-61 T 28-03-2018 MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 Pfam PF00563 EAL domain 699 932 3.0E-70 T 28-03-2018 IPR001633 EAL domain MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 Pfam PF13426 PAS domain 406 508 9.1E-12 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 SUPERFAMILY SSF55785 406 516 5.8E-23 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 SMART SM00091 395 462 0.0028 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 SMART SM00091 141 209 6.2E-4 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 SMART SM00091 269 337 6.5E-4 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 Pfam PF08447 PAS fold 294 381 1.1E-22 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 Gene3D G3DSA:3.40.50.2300 2 145 3.2E-39 T 28-03-2018 MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 Gene3D G3DSA:3.30.450.20 264 394 1.2E-35 T 28-03-2018 MKLM6_RS13395 0ba57f558c6ef461a687748046e6e0db 945 SUPERFAMILY SSF52172 6 167 3.27E-40 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS20885 d8397ae33a0e3c1fcfc15493a95e003c 277 Gene3D G3DSA:3.30.572.10 1 277 9.4E-115 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MKLM6_RS20885 d8397ae33a0e3c1fcfc15493a95e003c 277 PRINTS PR00108 Thymidylate synthase family signature 172 198 5.3E-35 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MKLM6_RS20885 d8397ae33a0e3c1fcfc15493a95e003c 277 PRINTS PR00108 Thymidylate synthase family signature 210 227 5.3E-35 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MKLM6_RS20885 d8397ae33a0e3c1fcfc15493a95e003c 277 PRINTS PR00108 Thymidylate synthase family signature 154 169 5.3E-35 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MKLM6_RS20885 d8397ae33a0e3c1fcfc15493a95e003c 277 PRINTS PR00108 Thymidylate synthase family signature 42 63 5.3E-35 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MKLM6_RS20885 d8397ae33a0e3c1fcfc15493a95e003c 277 Pfam PF00303 Thymidylate synthase 3 277 3.9E-108 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MKLM6_RS20885 d8397ae33a0e3c1fcfc15493a95e003c 277 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 3 84 1.6E-39 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MKLM6_RS20885 d8397ae33a0e3c1fcfc15493a95e003c 277 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 85 277 7.1E-71 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MKLM6_RS20885 d8397ae33a0e3c1fcfc15493a95e003c 277 SUPERFAMILY SSF55831 1 277 1.31E-114 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MKLM6_RS20885 d8397ae33a0e3c1fcfc15493a95e003c 277 Hamap MF_00008 Thymidylate synthase [thyA]. 1 277 37.722 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MKLM6_RS05640 d495e28efd75845018d909f87ef514a8 312 Gene3D G3DSA:3.40.50.720 1 131 4.0E-40 T 28-03-2018 MKLM6_RS05640 d495e28efd75845018d909f87ef514a8 312 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 120 3.0E-31 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MKLM6_RS05640 d495e28efd75845018d909f87ef514a8 312 Gene3D G3DSA:3.30.360.10 132 309 1.1E-22 T 28-03-2018 MKLM6_RS05640 d495e28efd75845018d909f87ef514a8 312 SUPERFAMILY SSF55347 145 293 5.89E-11 T 28-03-2018 MKLM6_RS05640 d495e28efd75845018d909f87ef514a8 312 SUPERFAMILY SSF51735 3 158 1.03E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS17675 d6e08dc479a1bdae0286990f79d46ea4 433 SUPERFAMILY SSF56935 219 412 7.06E-8 T 28-03-2018 MKLM6_RS17675 d6e08dc479a1bdae0286990f79d46ea4 433 Pfam PF07642 Putative beta-barrel porin-2, OmpL-like. bbp2 50 433 1.6E-85 T 28-03-2018 IPR011486 Putative beta-barrel porin-2, OmpL-like. bbp2 MKLM6_RS17675 d6e08dc479a1bdae0286990f79d46ea4 433 Gene3D G3DSA:2.40.160.10 45 433 3.2E-20 T 28-03-2018 MKLM6_RS20710 193d97ea29771e6622ee06e93e8392fc 409 TIGRFAM TIGR00127 nadp_idh_euk: isocitrate dehydrogenase, NADP-dependent 2 407 1.2E-218 T 28-03-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 MKLM6_RS20710 193d97ea29771e6622ee06e93e8392fc 409 PIRSF PIRSF000108 1 409 2.5E-229 T 28-03-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 MKLM6_RS20710 193d97ea29771e6622ee06e93e8392fc 409 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 8 395 5.1E-74 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MKLM6_RS20710 193d97ea29771e6622ee06e93e8392fc 409 Gene3D G3DSA:3.40.718.10 1 409 1.0E-136 T 28-03-2018 MKLM6_RS20710 193d97ea29771e6622ee06e93e8392fc 409 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 270 289 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 MKLM6_RS20710 193d97ea29771e6622ee06e93e8392fc 409 SUPERFAMILY SSF53659 1 406 2.3E-154 T 28-03-2018 MKLM6_RS20710 193d97ea29771e6622ee06e93e8392fc 409 SMART SM01329 9 399 1.5E-133 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MKLM6_RS12650 938b36574d5b6ff4feba01c3506a6bd7 311 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 282 2.5E-127 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MKLM6_RS12650 938b36574d5b6ff4feba01c3506a6bd7 311 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 253 262 1.2E-36 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MKLM6_RS12650 938b36574d5b6ff4feba01c3506a6bd7 311 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 165 183 1.2E-36 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MKLM6_RS12650 938b36574d5b6ff4feba01c3506a6bd7 311 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 131 145 1.2E-36 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MKLM6_RS12650 938b36574d5b6ff4feba01c3506a6bd7 311 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 231 242 1.2E-36 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MKLM6_RS12650 938b36574d5b6ff4feba01c3506a6bd7 311 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 202 219 1.2E-36 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MKLM6_RS12650 938b36574d5b6ff4feba01c3506a6bd7 311 SUPERFAMILY SSF52096 27 281 1.64E-83 T 28-03-2018 IPR029045 ClpP/crotonase-like domain MKLM6_RS12650 938b36574d5b6ff4feba01c3506a6bd7 311 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 283 38.151 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MKLM6_RS12650 938b36574d5b6ff4feba01c3506a6bd7 311 Gene3D G3DSA:3.90.226.10 14 290 6.0E-66 T 28-03-2018 MKLM6_RS12650 938b36574d5b6ff4feba01c3506a6bd7 311 Pfam PF01039 Carboxyl transferase domain 101 242 2.4E-15 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 MKLM6_RS20230 8fcc8858707b1b2f1d107553f095b54f 193 SUPERFAMILY SSF46609 1 84 2.49E-36 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MKLM6_RS20230 8fcc8858707b1b2f1d107553f095b54f 193 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 3.4E-22 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MKLM6_RS20230 8fcc8858707b1b2f1d107553f095b54f 193 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 3.4E-22 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MKLM6_RS20230 8fcc8858707b1b2f1d107553f095b54f 193 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 3.4E-22 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MKLM6_RS20230 8fcc8858707b1b2f1d107553f095b54f 193 PRINTS PR01703 Manganese superoxide dismutase signature 155 167 3.4E-22 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MKLM6_RS20230 8fcc8858707b1b2f1d107553f095b54f 193 PRINTS PR01703 Manganese superoxide dismutase signature 65 78 3.4E-22 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MKLM6_RS20230 8fcc8858707b1b2f1d107553f095b54f 193 Gene3D G3DSA:1.10.287.990 20 82 1.8E-27 T 28-03-2018 MKLM6_RS20230 8fcc8858707b1b2f1d107553f095b54f 193 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 89 189 2.4E-39 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MKLM6_RS20230 8fcc8858707b1b2f1d107553f095b54f 193 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 82 3.8E-35 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MKLM6_RS20230 8fcc8858707b1b2f1d107553f095b54f 193 SUPERFAMILY SSF54719 82 192 2.36E-46 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MKLM6_RS20230 8fcc8858707b1b2f1d107553f095b54f 193 PIRSF PIRSF000349 1 193 2.0E-86 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MKLM6_RS20230 8fcc8858707b1b2f1d107553f095b54f 193 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 157 164 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MKLM6_RS11885 5c0b39c0386ed3652a076b1af1d07266 138 SUPERFAMILY SSF46785 4 133 4.05E-42 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS11885 5c0b39c0386ed3652a076b1af1d07266 138 Pfam PF01475 Ferric uptake regulator family 9 129 9.3E-45 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 MKLM6_RS11885 5c0b39c0386ed3652a076b1af1d07266 138 Gene3D G3DSA:1.10.10.10 2 89 1.5E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS10115 5e7fa5279188b5e19e16984f28f59919 162 Gene3D G3DSA:2.40.50.180 31 92 1.4E-16 T 28-03-2018 MKLM6_RS10115 5e7fa5279188b5e19e16984f28f59919 162 Pfam PF01584 CheW-like domain 14 152 4.4E-36 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS10115 5e7fa5279188b5e19e16984f28f59919 162 Gene3D G3DSA:2.30.30.40 93 145 6.1E-16 T 28-03-2018 MKLM6_RS10115 5e7fa5279188b5e19e16984f28f59919 162 SMART SM00260 10 151 3.8E-44 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS10115 5e7fa5279188b5e19e16984f28f59919 162 SUPERFAMILY SSF50341 9 152 7.85E-38 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS15720 63a6ead28fd7654ad525d05c7631db9e 380 Pfam PF00534 Glycosyl transferases group 1 188 350 1.4E-35 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 MKLM6_RS15720 63a6ead28fd7654ad525d05c7631db9e 380 Gene3D G3DSA:3.40.50.2000 22 191 1.7E-16 T 28-03-2018 MKLM6_RS15720 63a6ead28fd7654ad525d05c7631db9e 380 SUPERFAMILY SSF53756 27 374 3.84E-73 T 28-03-2018 MKLM6_RS15720 63a6ead28fd7654ad525d05c7631db9e 380 Gene3D G3DSA:3.40.50.2000 192 356 4.2E-44 T 28-03-2018 MKLM6_RS15720 63a6ead28fd7654ad525d05c7631db9e 380 Pfam PF13477 Glycosyl transferase 4-like 4 154 6.0E-19 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MKLM6_RS12240 c4ba950702d99298ef9198d4dc21002d 255 Gene3D G3DSA:3.90.470.20 20 137 1.1E-21 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 MKLM6_RS12240 c4ba950702d99298ef9198d4dc21002d 255 Gene3D G3DSA:3.90.470.20 138 233 8.1E-15 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 MKLM6_RS12240 c4ba950702d99298ef9198d4dc21002d 255 SUPERFAMILY SSF56214 126 242 3.53E-23 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 MKLM6_RS12240 c4ba950702d99298ef9198d4dc21002d 255 SUPERFAMILY SSF56214 21 118 5.13E-22 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 MKLM6_RS12240 c4ba950702d99298ef9198d4dc21002d 255 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 127 220 5.6E-13 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 MKLM6_RS20305 b4678034522edf94f2458c116b55d618 515 SMART SM00331 287 514 1.4E-17 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS20305 b4678034522edf94f2458c116b55d618 515 TIGRFAM TIGR03373 VI_minor_4: type VI secretion-associated protein, BMA_A0400 family 15 145 1.2E-46 T 28-03-2018 IPR017748 Type VI secretion system-associated, BMAA0400 MKLM6_RS20305 b4678034522edf94f2458c116b55d618 515 Pfam PF13672 Protein phosphatase 2C 292 477 1.8E-12 T 28-03-2018 MKLM6_RS20305 b4678034522edf94f2458c116b55d618 515 SUPERFAMILY SSF81606 280 514 5.62E-53 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS20305 b4678034522edf94f2458c116b55d618 515 SMART SM00332 273 512 1.6E-15 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS20305 b4678034522edf94f2458c116b55d618 515 Pfam PF09867 Uncharacterized protein conserved in bacteria (DUF2094) 15 146 3.1E-46 T 28-03-2018 IPR017748 Type VI secretion system-associated, BMAA0400 MKLM6_RS20305 b4678034522edf94f2458c116b55d618 515 Gene3D G3DSA:3.40.1730.10 12 249 1.1E-62 T 28-03-2018 MKLM6_RS20305 b4678034522edf94f2458c116b55d618 515 Gene3D G3DSA:3.60.40.10 282 514 4.6E-34 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS15770 b1642a93e078db4faf4af398062314dc 260 Pfam PF04989 Cephalosporin hydroxylase 39 258 1.6E-95 T 28-03-2018 IPR007072 Rhamnosyl O-methyltransferase/Cephalosporin hydroxylase GO:0008168|GO:0008610 MKLM6_RS15770 b1642a93e078db4faf4af398062314dc 260 SUPERFAMILY SSF53335 21 258 6.16E-46 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS15770 b1642a93e078db4faf4af398062314dc 260 Gene3D G3DSA:3.40.50.150 6 249 3.1E-8 T 28-03-2018 MKLM6_RS14655 17fdd52cb494fa5ddd968168a11abba5 488 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 8 488 1.8E-180 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MKLM6_RS14655 17fdd52cb494fa5ddd968168a11abba5 488 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 8 488 82.727 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MKLM6_RS14655 17fdd52cb494fa5ddd968168a11abba5 488 Gene3D G3DSA:3.30.360.10 187 488 4.5E-122 T 28-03-2018 MKLM6_RS14655 17fdd52cb494fa5ddd968168a11abba5 488 SUPERFAMILY SSF51735 4 188 7.87E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS14655 17fdd52cb494fa5ddd968168a11abba5 488 Gene3D G3DSA:3.40.50.720 6 186 2.9E-57 T 28-03-2018 MKLM6_RS14655 17fdd52cb494fa5ddd968168a11abba5 488 PIRSF PIRSF000110 1 488 3.4E-167 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MKLM6_RS14655 17fdd52cb494fa5ddd968168a11abba5 488 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 187 486 1.0E-113 T 28-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MKLM6_RS14655 17fdd52cb494fa5ddd968168a11abba5 488 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 217 234 4.4E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MKLM6_RS14655 17fdd52cb494fa5ddd968168a11abba5 488 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 141 154 4.4E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MKLM6_RS14655 17fdd52cb494fa5ddd968168a11abba5 488 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 235 251 4.4E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MKLM6_RS14655 17fdd52cb494fa5ddd968168a11abba5 488 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 165 193 4.4E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MKLM6_RS14655 17fdd52cb494fa5ddd968168a11abba5 488 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 326 352 4.4E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MKLM6_RS14655 17fdd52cb494fa5ddd968168a11abba5 488 SUPERFAMILY SSF55347 175 486 2.78E-110 T 28-03-2018 MKLM6_RS14655 17fdd52cb494fa5ddd968168a11abba5 488 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 12 185 7.4E-52 T 28-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MKLM6_RS14655 17fdd52cb494fa5ddd968168a11abba5 488 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 175 181 - T 28-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MKLM6_RS20760 86d7067d67f0d52431df7cb8924d6357 190 Pfam PF12804 MobA-like NTP transferase domain 6 163 6.0E-37 T 28-03-2018 IPR025877 MobA-like NTP transferase MKLM6_RS20760 86d7067d67f0d52431df7cb8924d6357 190 SUPERFAMILY SSF53448 3 187 1.03E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS20760 86d7067d67f0d52431df7cb8924d6357 190 Gene3D G3DSA:3.90.550.10 1 190 4.4E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS01270 6ae6ddab2ecd7c1a39a4fa28f4dd5e89 157 Gene3D G3DSA:1.20.120.10 37 136 7.0E-5 T 28-03-2018 MKLM6_RS01270 6ae6ddab2ecd7c1a39a4fa28f4dd5e89 157 SUPERFAMILY SSF47175 96 135 5.59E-5 T 28-03-2018 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 MKLM6_RS10135 2af8fb249c76146785165beaa2f24b94 166 Pfam PF13466 STAS domain 82 152 4.6E-10 T 28-03-2018 IPR002645 STAS domain MKLM6_RS10135 2af8fb249c76146785165beaa2f24b94 166 SUPERFAMILY SSF52091 81 158 3.34E-6 T 28-03-2018 IPR002645 STAS domain MKLM6_RS10135 2af8fb249c76146785165beaa2f24b94 166 Gene3D G3DSA:3.30.750.24 67 165 3.6E-4 T 28-03-2018 IPR002645 STAS domain MKLM6_RS02215 a964081d3b8588c500af0c71e826616c 150 Gene3D G3DSA:3.90.1170.40 1 149 1.2E-47 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MKLM6_RS02215 a964081d3b8588c500af0c71e826616c 150 SUPERFAMILY SSF54690 14 146 1.07E-42 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MKLM6_RS02215 a964081d3b8588c500af0c71e826616c 150 Pfam PF02391 MoaE protein 24 122 1.7E-30 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MKLM6_RS20335 ddd30452b37b3c3fcd2f716e7ed1fbd1 414 TIGRFAM TIGR03079 CH4_NH3mon_ox_B: methane monooxygenase/ammonia monooxygenase, subunit B 19 413 1.5E-158 T 28-03-2018 IPR006833 Ammonia monooxygenase/particulate methane monooxygenase, subunit B MKLM6_RS20335 ddd30452b37b3c3fcd2f716e7ed1fbd1 414 Pfam PF04744 Monooxygenase subunit B protein 34 413 4.7E-179 T 28-03-2018 IPR006833 Ammonia monooxygenase/particulate methane monooxygenase, subunit B MKLM6_RS20335 ddd30452b37b3c3fcd2f716e7ed1fbd1 414 Gene3D G3DSA:2.60.40.1580 277 414 2.8E-41 T 28-03-2018 MKLM6_RS20335 ddd30452b37b3c3fcd2f716e7ed1fbd1 414 Gene3D G3DSA:2.60.120.570 33 184 1.1E-69 T 28-03-2018 IPR023301 Ammonia/methane monooxygenase, subunitB, N-terminal MKLM6_RS16635 5a2ec42bda925e596afa61e8ef6f23b0 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 199 215 5.3E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MKLM6_RS16635 5a2ec42bda925e596afa61e8ef6f23b0 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 294 5.3E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MKLM6_RS16635 5a2ec42bda925e596afa61e8ef6f23b0 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 5.3E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MKLM6_RS16635 5a2ec42bda925e596afa61e8ef6f23b0 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 5.3E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MKLM6_RS16635 5a2ec42bda925e596afa61e8ef6f23b0 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 5.3E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MKLM6_RS16635 5a2ec42bda925e596afa61e8ef6f23b0 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 5.3E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MKLM6_RS16635 5a2ec42bda925e596afa61e8ef6f23b0 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 5.3E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MKLM6_RS16635 5a2ec42bda925e596afa61e8ef6f23b0 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 238 259 5.3E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MKLM6_RS16635 5a2ec42bda925e596afa61e8ef6f23b0 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 5.3E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MKLM6_RS16635 5a2ec42bda925e596afa61e8ef6f23b0 318 Gene3D G3DSA:3.50.50.60 265 316 2.7E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS16635 5a2ec42bda925e596afa61e8ef6f23b0 318 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 MKLM6_RS16635 5a2ec42bda925e596afa61e8ef6f23b0 318 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 313 3.3E-122 T 28-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 MKLM6_RS16635 5a2ec42bda925e596afa61e8ef6f23b0 318 Gene3D G3DSA:3.40.50.720 137 264 1.3E-23 T 28-03-2018 MKLM6_RS16635 5a2ec42bda925e596afa61e8ef6f23b0 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 5.8E-40 T 28-03-2018 MKLM6_RS16635 5a2ec42bda925e596afa61e8ef6f23b0 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 5.8E-40 T 28-03-2018 MKLM6_RS16635 5a2ec42bda925e596afa61e8ef6f23b0 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 5.8E-40 T 28-03-2018 MKLM6_RS16635 5a2ec42bda925e596afa61e8ef6f23b0 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 5.8E-40 T 28-03-2018 MKLM6_RS16635 5a2ec42bda925e596afa61e8ef6f23b0 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 5.8E-40 T 28-03-2018 MKLM6_RS16635 5a2ec42bda925e596afa61e8ef6f23b0 318 Gene3D G3DSA:3.50.50.60 1 136 4.2E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS16635 5a2ec42bda925e596afa61e8ef6f23b0 318 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 301 2.3E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS16635 5a2ec42bda925e596afa61e8ef6f23b0 318 SUPERFAMILY SSF51905 2 313 9.16E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS02940 a1f65f3069c76773924711fd58b1c22c 193 Pfam PF02441 Flavoprotein 5 167 1.7E-24 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MKLM6_RS02940 a1f65f3069c76773924711fd58b1c22c 193 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 5 190 35.592 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 MKLM6_RS02940 a1f65f3069c76773924711fd58b1c22c 193 SUPERFAMILY SSF52507 5 181 2.35E-59 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MKLM6_RS02940 a1f65f3069c76773924711fd58b1c22c 193 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 6 181 6.6E-70 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 MKLM6_RS02940 a1f65f3069c76773924711fd58b1c22c 193 Gene3D G3DSA:3.40.50.1950 5 191 1.1E-49 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MKLM6_RS15630 328171b903eb3da593f62784638aba43 256 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 2 30 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MKLM6_RS15630 328171b903eb3da593f62784638aba43 256 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 174 254 7.9E-28 T 28-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 MKLM6_RS15630 328171b903eb3da593f62784638aba43 256 PIRSF PIRSF000456 1 256 4.6E-101 T 28-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 MKLM6_RS15630 328171b903eb3da593f62784638aba43 256 Gene3D G3DSA:1.20.1180.10 191 256 3.7E-21 T 28-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 MKLM6_RS15630 328171b903eb3da593f62784638aba43 256 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 16 46 1.2E-7 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS15630 328171b903eb3da593f62784638aba43 256 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 104 137 8.3E-8 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS15630 328171b903eb3da593f62784638aba43 256 Gene3D G3DSA:2.160.10.10 1 190 1.2E-46 T 28-03-2018 MKLM6_RS15630 328171b903eb3da593f62784638aba43 256 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 1 256 41.994 T 28-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 MKLM6_RS15630 328171b903eb3da593f62784638aba43 256 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 2 254 1.9E-99 T 28-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 MKLM6_RS15630 328171b903eb3da593f62784638aba43 256 SUPERFAMILY SSF51161 1 256 5.33E-79 T 28-03-2018 IPR011004 Trimeric LpxA-like MKLM6_RS16810 5d1993e2271af06c20819d1b55173327 425 Pfam PF07724 AAA domain (Cdc48 subfamily) 113 311 8.0E-47 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MKLM6_RS16810 5d1993e2271af06c20819d1b55173327 425 Gene3D G3DSA:3.40.50.300 60 315 1.6E-68 T 28-03-2018 MKLM6_RS16810 5d1993e2271af06c20819d1b55173327 425 SMART SM01086 317 412 1.2E-31 T 28-03-2018 IPR019489 Clp ATPase, C-terminal MKLM6_RS16810 5d1993e2271af06c20819d1b55173327 425 SMART SM00382 112 333 1.6E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS16810 5d1993e2271af06c20819d1b55173327 425 Gene3D G3DSA:1.10.8.60 317 408 1.7E-32 T 28-03-2018 MKLM6_RS16810 5d1993e2271af06c20819d1b55173327 425 SUPERFAMILY SSF52540 65 401 1.8E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS16810 5d1993e2271af06c20819d1b55173327 425 SUPERFAMILY SSF57716 14 49 1.13E-11 T 28-03-2018 MKLM6_RS16810 5d1993e2271af06c20819d1b55173327 425 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 415 52.687 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 MKLM6_RS16810 5d1993e2271af06c20819d1b55173327 425 Pfam PF06689 ClpX C4-type zinc finger 14 50 6.1E-20 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 MKLM6_RS16810 5d1993e2271af06c20819d1b55173327 425 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 317 395 4.5E-16 T 28-03-2018 IPR019489 Clp ATPase, C-terminal MKLM6_RS16810 5d1993e2271af06c20819d1b55173327 425 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 10 411 1.1E-202 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 MKLM6_RS16810 5d1993e2271af06c20819d1b55173327 425 SMART SM00994 13 52 4.0E-23 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 MKLM6_RS19995 1792e90f8324ed576c65f85b29de467f 114 Pfam PF04355 SmpA / OmlA family 43 106 8.7E-6 T 28-03-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 MKLM6_RS02980 fc2f96c217f485a60f97c2a36c731fcd 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 8.8E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS02980 fc2f96c217f485a60f97c2a36c731fcd 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 8.8E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS02980 fc2f96c217f485a60f97c2a36c731fcd 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 8.8E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS02980 fc2f96c217f485a60f97c2a36c731fcd 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 8.8E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS02980 fc2f96c217f485a60f97c2a36c731fcd 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 8.8E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS02980 fc2f96c217f485a60f97c2a36c731fcd 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 8.8E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS02980 fc2f96c217f485a60f97c2a36c731fcd 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MKLM6_RS02980 fc2f96c217f485a60f97c2a36c731fcd 243 SUPERFAMILY SSF51735 3 241 3.19E-66 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS02980 fc2f96c217f485a60f97c2a36c731fcd 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 238 8.3E-49 T 28-03-2018 MKLM6_RS02980 fc2f96c217f485a60f97c2a36c731fcd 243 Gene3D G3DSA:3.40.50.720 2 243 2.3E-57 T 28-03-2018 MKLM6_RS02980 fc2f96c217f485a60f97c2a36c731fcd 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.6E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS02980 fc2f96c217f485a60f97c2a36c731fcd 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.6E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS02980 fc2f96c217f485a60f97c2a36c731fcd 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.6E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS04880 83b72938b25057eebf3b63eccbaaea7e 294 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 7 86 6.8E-18 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MKLM6_RS04880 83b72938b25057eebf3b63eccbaaea7e 294 SUPERFAMILY SSF56349 107 292 1.8E-59 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS04880 83b72938b25057eebf3b63eccbaaea7e 294 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 5 294 58.369 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD MKLM6_RS04880 83b72938b25057eebf3b63eccbaaea7e 294 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 3 294 59.83 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 MKLM6_RS04880 83b72938b25057eebf3b63eccbaaea7e 294 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 9 293 1.4E-118 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 MKLM6_RS04880 83b72938b25057eebf3b63eccbaaea7e 294 Gene3D G3DSA:1.10.150.130 3 103 5.3E-23 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal MKLM6_RS04880 83b72938b25057eebf3b63eccbaaea7e 294 Gene3D G3DSA:1.10.443.10 108 288 6.1E-52 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS04880 83b72938b25057eebf3b63eccbaaea7e 294 SUPERFAMILY SSF47823 4 97 3.53E-28 T 28-03-2018 IPR010998 Integrase, Lambda-type, N-terminal MKLM6_RS04880 83b72938b25057eebf3b63eccbaaea7e 294 Pfam PF00589 Phage integrase family 110 280 9.0E-54 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS21600 66582a78439cfa0386aff9ddc0b97d55 171 Pfam PF00186 Dihydrofolate reductase 2 160 1.3E-59 T 28-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 MKLM6_RS21600 66582a78439cfa0386aff9ddc0b97d55 171 PRINTS PR00070 Dihydrofolate reductase signature 41 52 1.8E-14 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 MKLM6_RS21600 66582a78439cfa0386aff9ddc0b97d55 171 PRINTS PR00070 Dihydrofolate reductase signature 14 24 1.8E-14 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 MKLM6_RS21600 66582a78439cfa0386aff9ddc0b97d55 171 PRINTS PR00070 Dihydrofolate reductase signature 92 106 1.8E-14 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 MKLM6_RS21600 66582a78439cfa0386aff9ddc0b97d55 171 PRINTS PR00070 Dihydrofolate reductase signature 28 36 1.8E-14 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 MKLM6_RS21600 66582a78439cfa0386aff9ddc0b97d55 171 Gene3D G3DSA:3.40.430.10 38 161 8.2E-40 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 MKLM6_RS21600 66582a78439cfa0386aff9ddc0b97d55 171 Gene3D G3DSA:3.40.430.10 1 37 1.8E-13 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 MKLM6_RS21600 66582a78439cfa0386aff9ddc0b97d55 171 SUPERFAMILY SSF53597 1 160 8.9E-54 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 MKLM6_RS21600 66582a78439cfa0386aff9ddc0b97d55 171 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 14 36 - T 28-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 MKLM6_RS21600 66582a78439cfa0386aff9ddc0b97d55 171 PIRSF PIRSF000194 1 163 3.2E-62 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 MKLM6_RS03165 bb5d2baf5604fe39b83b04a7384da59e 243 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 7 226 5.1E-38 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 MKLM6_RS03165 bb5d2baf5604fe39b83b04a7384da59e 243 SUPERFAMILY SSF51219 6 235 1.46E-78 T 28-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain MKLM6_RS03165 bb5d2baf5604fe39b83b04a7384da59e 243 Pfam PF01987 Mitochondrial biogenesis AIM24 8 222 6.2E-65 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 MKLM6_RS03165 bb5d2baf5604fe39b83b04a7384da59e 243 Gene3D G3DSA:3.60.160.10 1 243 1.5E-72 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 MKLM6_RS13640 e2663e0d1b119c3ce62eae0d4442f68e 438 SUPERFAMILY SSF55729 292 418 5.4E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS13640 e2663e0d1b119c3ce62eae0d4442f68e 438 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 437 198.345 T 28-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 MKLM6_RS13640 e2663e0d1b119c3ce62eae0d4442f68e 438 PIRSF PIRSF000423 1 437 9.2E-187 T 28-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 MKLM6_RS13640 e2663e0d1b119c3ce62eae0d4442f68e 438 Pfam PF00583 Acetyltransferase (GNAT) family 331 398 8.9E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 MKLM6_RS13640 e2663e0d1b119c3ce62eae0d4442f68e 438 SUPERFAMILY SSF53633 5 286 8.1E-67 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MKLM6_RS13640 e2663e0d1b119c3ce62eae0d4442f68e 438 Pfam PF00696 Amino acid kinase family 25 264 1.5E-24 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MKLM6_RS13640 e2663e0d1b119c3ce62eae0d4442f68e 438 Gene3D G3DSA:3.40.630.30 292 437 1.7E-21 T 28-03-2018 MKLM6_RS13640 e2663e0d1b119c3ce62eae0d4442f68e 438 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 7 435 3.5E-174 T 28-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 MKLM6_RS13640 e2663e0d1b119c3ce62eae0d4442f68e 438 Gene3D G3DSA:3.40.1160.10 5 290 1.4E-60 T 28-03-2018 MKLM6_RS09240 3156599c1d0e8c1f145ce85a940670cb 413 Pfam PF13439 Glycosyltransferase Family 4 29 206 1.6E-13 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MKLM6_RS09240 3156599c1d0e8c1f145ce85a940670cb 413 SUPERFAMILY SSF53756 28 405 1.36E-79 T 28-03-2018 MKLM6_RS09240 3156599c1d0e8c1f145ce85a940670cb 413 Pfam PF00534 Glycosyl transferases group 1 220 385 6.9E-43 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 MKLM6_RS09240 3156599c1d0e8c1f145ce85a940670cb 413 Gene3D G3DSA:3.40.50.2000 213 385 2.4E-43 T 28-03-2018 MKLM6_RS09240 3156599c1d0e8c1f145ce85a940670cb 413 Gene3D G3DSA:3.40.50.2000 29 212 3.6E-11 T 28-03-2018 MKLM6_RS09400 1d4d6482ebf7e54b839931a68982a645 542 Gene3D G3DSA:3.30.70.270 108 278 2.3E-37 T 28-03-2018 MKLM6_RS09400 1d4d6482ebf7e54b839931a68982a645 542 Pfam PF00990 Diguanylate cyclase, GGDEF domain 116 268 1.8E-31 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS09400 1d4d6482ebf7e54b839931a68982a645 542 SMART SM00052 285 530 3.8E-109 T 28-03-2018 IPR001633 EAL domain MKLM6_RS09400 1d4d6482ebf7e54b839931a68982a645 542 Gene3D G3DSA:3.20.20.450 279 542 2.1E-100 T 28-03-2018 IPR001633 EAL domain MKLM6_RS09400 1d4d6482ebf7e54b839931a68982a645 542 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 114 271 1.7E-24 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS09400 1d4d6482ebf7e54b839931a68982a645 542 SUPERFAMILY SSF55073 121 273 7.06E-30 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS09400 1d4d6482ebf7e54b839931a68982a645 542 Pfam PF00563 EAL domain 291 525 7.9E-74 T 28-03-2018 IPR001633 EAL domain MKLM6_RS09400 1d4d6482ebf7e54b839931a68982a645 542 SUPERFAMILY SSF141868 291 537 2.75E-90 T 28-03-2018 IPR001633 EAL domain MKLM6_RS09400 1d4d6482ebf7e54b839931a68982a645 542 SMART SM00267 104 276 9.0E-30 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS05770 47e6f4ecf2727c9f59c4c5aef21d35dd 176 Gene3D G3DSA:3.40.50.10070 10 156 3.6E-6 T 28-03-2018 MKLM6_RS05770 47e6f4ecf2727c9f59c4c5aef21d35dd 176 Pfam PF11684 Protein of unknown function (DUF2380) 22 138 1.5E-17 T 28-03-2018 IPR021698 Protein of unknown function DUF2380 MKLM6_RS04535 b7944424ba5427d866826265be5bbe38 188 Pfam PF00196 Bacterial regulatory proteins, luxR family 122 176 1.8E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS04535 b7944424ba5427d866826265be5bbe38 188 SMART SM00421 120 177 2.2E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS04535 b7944424ba5427d866826265be5bbe38 188 SUPERFAMILY SSF46894 111 180 1.63E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MKLM6_RS04535 b7944424ba5427d866826265be5bbe38 188 ProSitePatterns PS00622 LuxR-type HTH domain signature. 137 164 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS04535 b7944424ba5427d866826265be5bbe38 188 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 137 153 2.9E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS04535 b7944424ba5427d866826265be5bbe38 188 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 123 137 2.9E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS04535 b7944424ba5427d866826265be5bbe38 188 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 165 2.9E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS04535 b7944424ba5427d866826265be5bbe38 188 Gene3D G3DSA:1.10.10.10 56 184 5.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS03870 a7bd83e3756aa1407a4e4ccef67471bb 200 Pfam PF07499 RuvA, C-terminal domain 155 196 3.1E-12 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 MKLM6_RS03870 a7bd83e3756aa1407a4e4ccef67471bb 200 SMART SM00278 108 127 0.094 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MKLM6_RS03870 a7bd83e3756aa1407a4e4ccef67471bb 200 SMART SM00278 73 92 1.4 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MKLM6_RS03870 a7bd83e3756aa1407a4e4ccef67471bb 200 Gene3D G3DSA:2.40.50.140 1 55 3.4E-24 T 28-03-2018 MKLM6_RS03870 a7bd83e3756aa1407a4e4ccef67471bb 200 Gene3D G3DSA:1.10.8.10 153 198 1.4E-13 T 28-03-2018 MKLM6_RS03870 a7bd83e3756aa1407a4e4ccef67471bb 200 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 198 4.8E-56 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 MKLM6_RS03870 a7bd83e3756aa1407a4e4ccef67471bb 200 Gene3D G3DSA:1.10.150.280 56 80 0.13 T 28-03-2018 MKLM6_RS03870 a7bd83e3756aa1407a4e4ccef67471bb 200 SUPERFAMILY SSF47781 67 136 3.95E-21 T 28-03-2018 IPR010994 RuvA domain 2-like MKLM6_RS03870 a7bd83e3756aa1407a4e4ccef67471bb 200 SUPERFAMILY SSF50249 2 63 2.17E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS03870 a7bd83e3756aa1407a4e4ccef67471bb 200 Pfam PF14520 Helix-hairpin-helix domain 72 128 2.2E-16 T 28-03-2018 MKLM6_RS03870 a7bd83e3756aa1407a4e4ccef67471bb 200 SUPERFAMILY SSF46929 154 196 1.57E-9 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 MKLM6_RS03870 a7bd83e3756aa1407a4e4ccef67471bb 200 Pfam PF01330 RuvA N terminal domain 2 62 1.4E-21 T 28-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 MKLM6_RS03870 a7bd83e3756aa1407a4e4ccef67471bb 200 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 199 30.117 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 MKLM6_RS03870 a7bd83e3756aa1407a4e4ccef67471bb 200 Gene3D G3DSA:1.10.150.20 81 142 8.9E-14 T 28-03-2018 MKLM6_RS14705 5c74518ec8fdd8cce20ca614e0ceb4aa 188 Pfam PF00578 AhpC/TSA family 12 130 1.0E-12 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MKLM6_RS14705 5c74518ec8fdd8cce20ca614e0ceb4aa 188 SUPERFAMILY SSF52833 5 186 1.56E-48 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS14705 5c74518ec8fdd8cce20ca614e0ceb4aa 188 Gene3D G3DSA:3.40.30.10 1 188 2.0E-41 T 28-03-2018 MKLM6_RS17255 bbca48f27315579058b60c2e1e64bc4d 238 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 75 3.3E-12 T 28-03-2018 MKLM6_RS17255 bbca48f27315579058b60c2e1e64bc4d 238 PIRSF PIRSF000309 1 233 1.5E-73 T 28-03-2018 IPR016214 NAD-reducing hydrogenase, HoxS gamma subunit MetaCyc: PWY-5382|MetaCyc: PWY-6758 MKLM6_RS17255 bbca48f27315579058b60c2e1e64bc4d 238 SMART SM00929 82 122 2.7E-8 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS17255 bbca48f27315579058b60c2e1e64bc4d 238 SUPERFAMILY SSF54292 4 71 5.79E-15 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MKLM6_RS17255 bbca48f27315579058b60c2e1e64bc4d 238 Gene3D G3DSA:3.10.20.30 2 148 7.0E-16 T 28-03-2018 IPR012675 Beta-grasp domain MKLM6_RS17255 bbca48f27315579058b60c2e1e64bc4d 238 SUPERFAMILY SSF54862 74 209 4.18E-27 T 28-03-2018 MKLM6_RS17255 bbca48f27315579058b60c2e1e64bc4d 238 Gene3D G3DSA:3.30.70.20 149 208 2.6E-5 T 28-03-2018 MKLM6_RS17255 bbca48f27315579058b60c2e1e64bc4d 238 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 86 118 8.9E-10 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS17255 bbca48f27315579058b60c2e1e64bc4d 238 Pfam PF13459 4Fe-4S single cluster domain 138 206 1.4E-11 T 28-03-2018 MKLM6_RS17255 bbca48f27315579058b60c2e1e64bc4d 238 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 97 109 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS10035 c77adb02e75df3f63896f27a057836c3 442 SUPERFAMILY SSF48256 8 435 1.14E-162 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 MKLM6_RS10035 c77adb02e75df3f63896f27a057836c3 442 ProSitePatterns PS00480 Citrate synthase signature. 310 322 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MKLM6_RS10035 c77adb02e75df3f63896f27a057836c3 442 Pfam PF00285 Citrate synthase, C-terminal domain 51 418 6.1E-136 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 MKLM6_RS10035 c77adb02e75df3f63896f27a057836c3 442 Gene3D G3DSA:1.10.580.10 349 411 2.5E-9 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain MKLM6_RS10035 c77adb02e75df3f63896f27a057836c3 442 PRINTS PR00143 Citrate synthase signature 248 276 4.7E-53 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 MKLM6_RS10035 c77adb02e75df3f63896f27a057836c3 442 PRINTS PR00143 Citrate synthase signature 366 382 4.7E-53 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 MKLM6_RS10035 c77adb02e75df3f63896f27a057836c3 442 PRINTS PR00143 Citrate synthase signature 226 241 4.7E-53 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 MKLM6_RS10035 c77adb02e75df3f63896f27a057836c3 442 PRINTS PR00143 Citrate synthase signature 303 323 4.7E-53 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 MKLM6_RS10035 c77adb02e75df3f63896f27a057836c3 442 PRINTS PR00143 Citrate synthase signature 167 180 4.7E-53 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 MKLM6_RS10035 c77adb02e75df3f63896f27a057836c3 442 PRINTS PR00143 Citrate synthase signature 386 400 4.7E-53 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 MKLM6_RS10035 c77adb02e75df3f63896f27a057836c3 442 PIRSF PIRSF001369 40 436 5.5E-163 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type MKLM6_RS10035 c77adb02e75df3f63896f27a057836c3 442 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 15 429 2.9E-204 T 28-03-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 MKLM6_RS10035 c77adb02e75df3f63896f27a057836c3 442 Gene3D G3DSA:1.10.580.10 53 315 9.0E-93 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain MKLM6_RS14970 722cb785ca499cc518d4247373732de2 258 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 2 254 5.6E-65 T 28-03-2018 MKLM6_RS14970 722cb785ca499cc518d4247373732de2 258 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 249 2.5E-18 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MKLM6_RS14970 722cb785ca499cc518d4247373732de2 258 SUPERFAMILY SSF56219 2 256 3.27E-73 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MKLM6_RS14970 722cb785ca499cc518d4247373732de2 258 Gene3D G3DSA:3.60.10.10 1 257 1.3E-52 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MKLM6_RS14970 722cb785ca499cc518d4247373732de2 258 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 29 38 - T 28-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 MKLM6_RS14970 722cb785ca499cc518d4247373732de2 258 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 2 255 1.1E-72 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 MKLM6_RS22290 f52a08c724d3dcc96cdb9c6dc4616053 372 Gene3D G3DSA:3.40.50.300 154 327 1.2E-7 T 28-03-2018 MKLM6_RS22290 f52a08c724d3dcc96cdb9c6dc4616053 372 SUPERFAMILY SSF52540 1 315 6.78E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS22290 f52a08c724d3dcc96cdb9c6dc4616053 372 Gene3D G3DSA:3.40.50.300 1 132 2.9E-16 T 28-03-2018 MKLM6_RS22290 f52a08c724d3dcc96cdb9c6dc4616053 372 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 24 310 6.9E-21 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MKLM6_RS07025 15f8af3fb5a1b77e2eff175dd5cf3e6e 58 Gene3D G3DSA:3.30.50.10 3 57 2.0E-4 T 28-03-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 MKLM6_RS18515 dcc8dcf61352ae3bfb0b5df671502114 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.8E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18515 dcc8dcf61352ae3bfb0b5df671502114 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 3.8E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18515 dcc8dcf61352ae3bfb0b5df671502114 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.8E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18515 dcc8dcf61352ae3bfb0b5df671502114 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 3.8E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18515 dcc8dcf61352ae3bfb0b5df671502114 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.8E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18515 dcc8dcf61352ae3bfb0b5df671502114 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 8.5E-18 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MKLM6_RS18515 dcc8dcf61352ae3bfb0b5df671502114 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 145 6.6E-15 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MKLM6_RS18515 dcc8dcf61352ae3bfb0b5df671502114 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 2.3E-225 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MKLM6_RS18515 dcc8dcf61352ae3bfb0b5df671502114 396 Gene3D G3DSA:2.40.30.10 302 395 3.6E-33 T 28-03-2018 MKLM6_RS18515 dcc8dcf61352ae3bfb0b5df671502114 396 SUPERFAMILY SSF50465 304 396 1.78E-36 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MKLM6_RS18515 dcc8dcf61352ae3bfb0b5df671502114 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.9E-58 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS18515 dcc8dcf61352ae3bfb0b5df671502114 396 Gene3D G3DSA:3.40.50.300 75 205 1.8E-28 T 28-03-2018 MKLM6_RS18515 dcc8dcf61352ae3bfb0b5df671502114 396 SUPERFAMILY SSF50447 207 303 4.12E-30 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain MKLM6_RS18515 dcc8dcf61352ae3bfb0b5df671502114 396 Gene3D G3DSA:2.40.30.10 208 298 9.0E-31 T 28-03-2018 MKLM6_RS18515 dcc8dcf61352ae3bfb0b5df671502114 396 Gene3D G3DSA:3.40.50.300 1 74 3.7E-12 T 28-03-2018 MKLM6_RS18515 dcc8dcf61352ae3bfb0b5df671502114 396 SUPERFAMILY SSF52540 6 221 1.85E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS18515 dcc8dcf61352ae3bfb0b5df671502114 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 59.796 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MKLM6_RS18515 dcc8dcf61352ae3bfb0b5df671502114 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 2.8E-34 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal MKLM6_RS18515 dcc8dcf61352ae3bfb0b5df671502114 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site MKLM6_RS02640 208b1a1100522069d4571dc7b573b9ad 335 Gene3D G3DSA:3.20.20.70 2 335 2.3E-150 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS02640 208b1a1100522069d4571dc7b573b9ad 335 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 276 291 1.4E-58 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MKLM6_RS02640 208b1a1100522069d4571dc7b573b9ad 335 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 128 142 1.4E-58 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MKLM6_RS02640 208b1a1100522069d4571dc7b573b9ad 335 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 197 216 1.4E-58 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MKLM6_RS02640 208b1a1100522069d4571dc7b573b9ad 335 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 159 178 1.4E-58 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MKLM6_RS02640 208b1a1100522069d4571dc7b573b9ad 335 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 251 267 1.4E-58 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MKLM6_RS02640 208b1a1100522069d4571dc7b573b9ad 335 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 306 325 1.4E-58 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MKLM6_RS02640 208b1a1100522069d4571dc7b573b9ad 335 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 251 263 - T 28-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MKLM6_RS02640 208b1a1100522069d4571dc7b573b9ad 335 SMART SM01004 8 332 1.7E-242 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MKLM6_RS02640 208b1a1100522069d4571dc7b573b9ad 335 Pfam PF00490 Delta-aminolevulinic acid dehydratase 11 331 4.6E-140 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MKLM6_RS02640 208b1a1100522069d4571dc7b573b9ad 335 SUPERFAMILY SSF51569 6 334 1.61E-143 T 28-03-2018 MKLM6_RS02640 208b1a1100522069d4571dc7b573b9ad 335 PIRSF PIRSF001415 2 335 1.6E-147 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MKLM6_RS13305 fd1f3b9167bd174d7b220403af12eb14 399 TIGRFAM TIGR01937 nqrB: NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit 4 394 1.6E-164 T 28-03-2018 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 MKLM6_RS13305 fd1f3b9167bd174d7b220403af12eb14 399 Hamap MF_00426 Na(+)-translocating NADH-quinone reductase subunit B [nqrB]. 2 398 36.671 T 28-03-2018 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 MKLM6_RS13305 fd1f3b9167bd174d7b220403af12eb14 399 PIRSF PIRSF016055 1 399 2.9E-185 T 28-03-2018 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 MKLM6_RS13305 fd1f3b9167bd174d7b220403af12eb14 399 Pfam PF03116 NQR2, RnfD, RnfE family 42 391 4.8E-102 T 28-03-2018 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 MKLM6_RS06765 c5878e2abaac77d79fd55a0a2beedcc1 257 SUPERFAMILY SSF52540 196 250 5.94E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS06765 c5878e2abaac77d79fd55a0a2beedcc1 257 SMART SM00382 26 214 1.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS06765 c5878e2abaac77d79fd55a0a2beedcc1 257 SUPERFAMILY SSF52540 2 182 3.75E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS06765 c5878e2abaac77d79fd55a0a2beedcc1 257 Pfam PF00005 ABC transporter 19 161 4.0E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS06765 c5878e2abaac77d79fd55a0a2beedcc1 257 Gene3D G3DSA:3.40.50.300 1 256 2.4E-52 T 28-03-2018 MKLM6_RS16305 8e64d883ffdc5f99e8f7a51538bb53d0 367 Pfam PF01420 Type I restriction modification DNA specificity domain 5 159 2.8E-8 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MKLM6_RS16305 8e64d883ffdc5f99e8f7a51538bb53d0 367 SUPERFAMILY SSF116734 4 165 2.29E-21 T 28-03-2018 MKLM6_RS16305 8e64d883ffdc5f99e8f7a51538bb53d0 367 SUPERFAMILY SSF116734 193 365 2.62E-19 T 28-03-2018 MKLM6_RS16305 8e64d883ffdc5f99e8f7a51538bb53d0 367 Gene3D G3DSA:3.90.220.20 181 329 5.6E-15 T 28-03-2018 MKLM6_RS16305 8e64d883ffdc5f99e8f7a51538bb53d0 367 Gene3D G3DSA:3.90.220.20 2 165 1.8E-21 T 28-03-2018 MKLM6_RS08525 8fc950b890f23759849b06afab5434ee 182 TIGRFAM TIGR01752 flav_long: flavodoxin 3 176 1.7E-54 T 28-03-2018 IPR010086 Flavodoxin, long chain GO:0010181 MKLM6_RS08525 8fc950b890f23759849b06afab5434ee 182 PRINTS PR00369 Flavodoxin signature 89 99 2.5E-5 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MKLM6_RS08525 8fc950b890f23759849b06afab5434ee 182 PRINTS PR00369 Flavodoxin signature 52 63 2.5E-5 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MKLM6_RS08525 8fc950b890f23759849b06afab5434ee 182 PRINTS PR00369 Flavodoxin signature 5 18 2.5E-5 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MKLM6_RS08525 8fc950b890f23759849b06afab5434ee 182 Pfam PF00258 Flavodoxin 6 168 1.1E-20 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MKLM6_RS08525 8fc950b890f23759849b06afab5434ee 182 Gene3D G3DSA:3.40.50.360 1 178 3.3E-30 T 28-03-2018 IPR029039 Flavoprotein-like domain MKLM6_RS08525 8fc950b890f23759849b06afab5434ee 182 PIRSF PIRSF038996 1 180 4.1E-52 T 28-03-2018 IPR010086 Flavodoxin, long chain GO:0010181 MKLM6_RS08525 8fc950b890f23759849b06afab5434ee 182 SUPERFAMILY SSF52218 1 176 1.71E-40 T 28-03-2018 IPR029039 Flavoprotein-like domain MKLM6_RS07825 3417b1fd5b8c4d1b43247b6da3012e9d 368 Gene3D G3DSA:3.40.718.10 1 366 2.0E-107 T 28-03-2018 MKLM6_RS07825 3417b1fd5b8c4d1b43247b6da3012e9d 368 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 248 267 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 MKLM6_RS07825 3417b1fd5b8c4d1b43247b6da3012e9d 368 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 358 2.3E-108 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MKLM6_RS07825 3417b1fd5b8c4d1b43247b6da3012e9d 368 SMART SM01329 5 358 3.5E-154 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MKLM6_RS07825 3417b1fd5b8c4d1b43247b6da3012e9d 368 SUPERFAMILY SSF53659 1 362 5.4E-106 T 28-03-2018 MKLM6_RS07825 3417b1fd5b8c4d1b43247b6da3012e9d 368 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 5 355 4.5E-111 T 28-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 MKLM6_RS03740 0a88abbb0c450b027fec6d355ed3ca61 347 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 31 320 7.2E-107 T 28-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 MKLM6_RS03740 0a88abbb0c450b027fec6d355ed3ca61 347 SUPERFAMILY SSF53659 3 326 7.56E-115 T 28-03-2018 MKLM6_RS03740 0a88abbb0c450b027fec6d355ed3ca61 347 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 5 323 4.4E-126 T 28-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 MKLM6_RS03740 0a88abbb0c450b027fec6d355ed3ca61 347 Gene3D G3DSA:3.40.718.10 1 328 9.7E-129 T 28-03-2018 MKLM6_RS03740 0a88abbb0c450b027fec6d355ed3ca61 347 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 2 324 35.579 T 28-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 MKLM6_RS21205 c340753505331e1a7dbb7a9a8b124a19 115 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 67 9.3E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS21205 c340753505331e1a7dbb7a9a8b124a19 115 Gene3D G3DSA:1.10.10.10 1 87 1.2E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS21205 c340753505331e1a7dbb7a9a8b124a19 115 SUPERFAMILY SSF46785 1 87 2.18E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS05625 5e9cb601f54637e57d4cfc2aa19fc9ae 469 SUPERFAMILY SSF46785 4 76 1.21E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS05625 5e9cb601f54637e57d4cfc2aa19fc9ae 469 SUPERFAMILY SSF53383 97 466 2.89E-97 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS05625 5e9cb601f54637e57d4cfc2aa19fc9ae 469 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 67 1.3E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MKLM6_RS05625 5e9cb601f54637e57d4cfc2aa19fc9ae 469 Gene3D G3DSA:1.10.10.10 2 69 1.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS05625 5e9cb601f54637e57d4cfc2aa19fc9ae 469 Gene3D G3DSA:3.40.640.10 133 345 4.7E-44 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS05625 5e9cb601f54637e57d4cfc2aa19fc9ae 469 Gene3D G3DSA:3.90.1150.10 346 468 4.5E-31 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS05625 5e9cb601f54637e57d4cfc2aa19fc9ae 469 Pfam PF00155 Aminotransferase class I and II 140 463 2.2E-35 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MKLM6_RS05625 5e9cb601f54637e57d4cfc2aa19fc9ae 469 SMART SM00345 8 67 1.4E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MKLM6_RS09435 cba1d3c551cff328fb78e84e70798fab 371 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 173 198 - T 28-03-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 Reactome: R-HSA-71403 MKLM6_RS09435 cba1d3c551cff328fb78e84e70798fab 371 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 195 1.0E-6 T 28-03-2018 MKLM6_RS09435 cba1d3c551cff328fb78e84e70798fab 371 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 15 37 1.0E-6 T 28-03-2018 MKLM6_RS09435 cba1d3c551cff328fb78e84e70798fab 371 PIRSF PIRSF000183 1 371 1.2E-154 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 MKLM6_RS09435 cba1d3c551cff328fb78e84e70798fab 371 SMART SM01002 149 297 1.2E-82 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MKLM6_RS09435 cba1d3c551cff328fb78e84e70798fab 371 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 1.1E-81 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MKLM6_RS09435 cba1d3c551cff328fb78e84e70798fab 371 SUPERFAMILY SSF52283 305 359 1.53E-65 T 28-03-2018 MKLM6_RS09435 cba1d3c551cff328fb78e84e70798fab 371 SUPERFAMILY SSF52283 1 137 1.53E-65 T 28-03-2018 MKLM6_RS09435 cba1d3c551cff328fb78e84e70798fab 371 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 2.2E-45 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MKLM6_RS09435 cba1d3c551cff328fb78e84e70798fab 371 SUPERFAMILY SSF51735 137 303 1.34E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS09435 cba1d3c551cff328fb78e84e70798fab 371 SMART SM01003 4 137 3.0E-74 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MKLM6_RS09435 cba1d3c551cff328fb78e84e70798fab 371 Gene3D G3DSA:3.40.50.720 191 371 3.0E-41 T 28-03-2018 MKLM6_RS09435 cba1d3c551cff328fb78e84e70798fab 371 Gene3D G3DSA:3.40.50.720 1 190 1.9E-49 T 28-03-2018 MKLM6_RS09435 cba1d3c551cff328fb78e84e70798fab 371 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 368 1.6E-155 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 MKLM6_RS16450 dfaf4cbef6848e83de6a22014c5d3faf 56 PRINTS PR00163 Rubredoxin signature 36 52 2.2E-9 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 MKLM6_RS16450 dfaf4cbef6848e83de6a22014c5d3faf 56 PRINTS PR00163 Rubredoxin signature 6 22 2.2E-9 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 MKLM6_RS16450 dfaf4cbef6848e83de6a22014c5d3faf 56 Pfam PF00301 Rubredoxin 6 52 8.9E-24 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 MKLM6_RS16450 dfaf4cbef6848e83de6a22014c5d3faf 56 ProSitePatterns PS00202 Rubredoxin signature. 36 46 - T 28-03-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 MKLM6_RS16450 dfaf4cbef6848e83de6a22014c5d3faf 56 Gene3D G3DSA:2.20.28.10 17 56 3.8E-24 T 28-03-2018 MKLM6_RS16450 dfaf4cbef6848e83de6a22014c5d3faf 56 SUPERFAMILY SSF57802 3 55 1.36E-21 T 28-03-2018 MKLM6_RS16450 dfaf4cbef6848e83de6a22014c5d3faf 56 Gene3D G3DSA:2.20.25.10 1 16 0.087 T 28-03-2018 MKLM6_RS16450 dfaf4cbef6848e83de6a22014c5d3faf 56 PIRSF PIRSF000071 3 56 1.7E-24 T 28-03-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 MKLM6_RS01330 b7a80cbdf3de116cdcd7e9df3d0d6f88 930 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 741 763 - T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MKLM6_RS01330 b7a80cbdf3de116cdcd7e9df3d0d6f88 930 PRINTS PR01183 Ribonucleotide reductase large chain signature 752 779 4.5E-42 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MKLM6_RS01330 b7a80cbdf3de116cdcd7e9df3d0d6f88 930 PRINTS PR01183 Ribonucleotide reductase large chain signature 611 634 4.5E-42 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MKLM6_RS01330 b7a80cbdf3de116cdcd7e9df3d0d6f88 930 PRINTS PR01183 Ribonucleotide reductase large chain signature 435 454 4.5E-42 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MKLM6_RS01330 b7a80cbdf3de116cdcd7e9df3d0d6f88 930 PRINTS PR01183 Ribonucleotide reductase large chain signature 677 700 4.5E-42 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MKLM6_RS01330 b7a80cbdf3de116cdcd7e9df3d0d6f88 930 PRINTS PR01183 Ribonucleotide reductase large chain signature 570 581 4.5E-42 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MKLM6_RS01330 b7a80cbdf3de116cdcd7e9df3d0d6f88 930 PRINTS PR01183 Ribonucleotide reductase large chain signature 649 671 4.5E-42 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MKLM6_RS01330 b7a80cbdf3de116cdcd7e9df3d0d6f88 930 Pfam PF02867 Ribonucleotide reductase, barrel domain 360 897 8.1E-182 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MKLM6_RS01330 b7a80cbdf3de116cdcd7e9df3d0d6f88 930 SUPERFAMILY SSF48168 148 358 1.24E-60 T 28-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MKLM6_RS01330 b7a80cbdf3de116cdcd7e9df3d0d6f88 930 Pfam PF03477 ATP cone domain 31 127 1.1E-17 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 MKLM6_RS01330 b7a80cbdf3de116cdcd7e9df3d0d6f88 930 Gene3D G3DSA:3.20.70.20 265 904 4.3E-211 T 28-03-2018 MKLM6_RS01330 b7a80cbdf3de116cdcd7e9df3d0d6f88 930 SUPERFAMILY SSF51998 359 801 7.94E-181 T 28-03-2018 MKLM6_RS01330 b7a80cbdf3de116cdcd7e9df3d0d6f88 930 SUPERFAMILY SSF51998 832 900 7.94E-181 T 28-03-2018 MKLM6_RS01330 b7a80cbdf3de116cdcd7e9df3d0d6f88 930 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 283 356 5.5E-24 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MKLM6_RS01330 b7a80cbdf3de116cdcd7e9df3d0d6f88 930 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 286 900 1.2E-214 T 28-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MKLM6_RS15340 7d9423c8624bbcebbb3ba7862f889a38 355 Pfam PF14907 Uncharacterised nucleotidyltransferase 23 270 1.2E-41 T 28-03-2018 MKLM6_RS10405 d837961593544c535528557891781f97 564 SUPERFAMILY SSF56935 187 374 7.32E-7 T 28-03-2018 MKLM6_RS10405 d837961593544c535528557891781f97 564 SUPERFAMILY SSF56935 418 540 7.32E-7 T 28-03-2018 MKLM6_RS10405 d837961593544c535528557891781f97 564 Pfam PF16930 Putative porin 31 564 3.8E-188 T 28-03-2018 IPR032638 Putative bacterial porin MKLM6_RS10405 d837961593544c535528557891781f97 564 Gene3D G3DSA:2.40.160.10 117 564 2.0E-33 T 28-03-2018 MKLM6_RS07215 8663d435dd5518c52cdf122ca934e1ca 317 SUPERFAMILY SSF46689 220 314 2.58E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS07215 8663d435dd5518c52cdf122ca934e1ca 317 SUPERFAMILY SSF52540 6 249 1.3E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS07215 8663d435dd5518c52cdf122ca934e1ca 317 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 220 229 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site MKLM6_RS07215 8663d435dd5518c52cdf122ca934e1ca 317 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 278 295 1.2E-13 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS07215 8663d435dd5518c52cdf122ca934e1ca 317 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 295 315 1.2E-13 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS07215 8663d435dd5518c52cdf122ca934e1ca 317 Pfam PF02954 Bacterial regulatory protein, Fis family 272 312 1.4E-13 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS07215 8663d435dd5518c52cdf122ca934e1ca 317 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 93 108 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MKLM6_RS07215 8663d435dd5518c52cdf122ca934e1ca 317 Gene3D G3DSA:1.10.8.60 180 248 1.9E-24 T 28-03-2018 MKLM6_RS07215 8663d435dd5518c52cdf122ca934e1ca 317 SMART SM00382 27 170 1.3E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS07215 8663d435dd5518c52cdf122ca934e1ca 317 Gene3D G3DSA:1.10.10.60 249 315 3.4E-17 T 28-03-2018 MKLM6_RS07215 8663d435dd5518c52cdf122ca934e1ca 317 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 31 44 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MKLM6_RS07215 8663d435dd5518c52cdf122ca934e1ca 317 Gene3D G3DSA:3.40.50.300 2 179 2.9E-29 T 28-03-2018 MKLM6_RS07215 8663d435dd5518c52cdf122ca934e1ca 317 Pfam PF00158 Sigma-54 interaction domain 7 173 6.3E-68 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MKLM6_RS02585 7f0fb2eb2b26eda78e45391a8346a74b 410 TIGRFAM TIGR00540 TPR_hemY_coli: heme biosynthesis-associated TPR protein 12 391 4.3E-83 T 28-03-2018 IPR005254 Heme biosynthesis-associated TPR protein GO:0016020|GO:0042168 MKLM6_RS02585 7f0fb2eb2b26eda78e45391a8346a74b 410 Gene3D G3DSA:1.25.40.10 224 402 1.5E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS02585 7f0fb2eb2b26eda78e45391a8346a74b 410 Pfam PF13181 Tetratricopeptide repeat 369 398 0.19 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS02585 7f0fb2eb2b26eda78e45391a8346a74b 410 Pfam PF07219 HemY protein N-terminus 32 138 2.5E-31 T 28-03-2018 IPR010817 HemY, N-terminal MKLM6_RS02585 7f0fb2eb2b26eda78e45391a8346a74b 410 Gene3D G3DSA:1.25.40.10 89 223 1.4E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS02585 7f0fb2eb2b26eda78e45391a8346a74b 410 SUPERFAMILY SSF48452 327 396 1.06E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS02585 7f0fb2eb2b26eda78e45391a8346a74b 410 SUPERFAMILY SSF48452 157 219 1.06E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS16785 ce169c2917b97418c289c3c671477067 622 SUPERFAMILY SSF54534 249 354 7.2E-28 T 28-03-2018 MKLM6_RS16785 ce169c2917b97418c289c3c671477067 622 SUPERFAMILY SSF109998 41 161 2.09E-25 T 28-03-2018 IPR027304 Trigger factor/SurA domain MKLM6_RS16785 ce169c2917b97418c289c3c671477067 622 SUPERFAMILY SSF109998 193 235 2.09E-25 T 28-03-2018 IPR027304 Trigger factor/SurA domain MKLM6_RS16785 ce169c2917b97418c289c3c671477067 622 Gene3D G3DSA:3.10.50.40 376 488 2.2E-7 T 28-03-2018 MKLM6_RS16785 ce169c2917b97418c289c3c671477067 622 Gene3D G3DSA:3.10.50.40 247 375 4.3E-34 T 28-03-2018 MKLM6_RS16785 ce169c2917b97418c289c3c671477067 622 Gene3D G3DSA:3.10.50.40 489 595 0.1 T 28-03-2018 MKLM6_RS16785 ce169c2917b97418c289c3c671477067 622 Pfam PF13624 SurA N-terminal domain 1 155 6.8E-38 T 28-03-2018 MKLM6_RS16785 ce169c2917b97418c289c3c671477067 622 Gene3D G3DSA:1.10.4030.10 37 161 7.2E-21 T 28-03-2018 MKLM6_RS16785 ce169c2917b97418c289c3c671477067 622 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 293 314 - T 28-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 MKLM6_RS16785 ce169c2917b97418c289c3c671477067 622 Pfam PF13616 PPIC-type PPIASE domain 254 354 2.7E-23 T 28-03-2018 MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 Gene3D G3DSA:3.30.450.20 83 214 6.4E-30 T 28-03-2018 MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 Pfam PF13185 GAF domain 547 686 2.4E-11 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 SUPERFAMILY SSF55073 825 983 7.85E-55 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 SMART SM00304 346 398 7.4E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 Pfam PF13426 PAS domain 706 808 2.5E-12 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 Pfam PF00990 Diguanylate cyclase, GGDEF domain 820 977 5.3E-55 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 Gene3D G3DSA:3.30.450.20 387 527 4.3E-26 T 28-03-2018 MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 SUPERFAMILY SSF55781 561 695 1.92E-20 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 SMART SM00052 991 1237 1.1E-112 T 28-03-2018 IPR001633 EAL domain MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 Pfam PF00563 EAL domain 998 1232 2.4E-72 T 28-03-2018 IPR001633 EAL domain MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 SUPERFAMILY SSF158472 346 394 9.29E-6 T 28-03-2018 MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 Gene3D G3DSA:3.30.450.20 703 815 6.8E-23 T 28-03-2018 MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 819 980 3.2E-48 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 Gene3D G3DSA:3.30.450.40 528 702 4.5E-21 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 SMART SM00267 808 981 1.5E-72 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 SUPERFAMILY SSF141868 997 1243 3.66E-89 T 28-03-2018 IPR001633 EAL domain MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 Pfam PF08448 PAS fold 411 522 7.4E-15 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 699 814 1.8E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 402 525 9.3E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 Gene3D G3DSA:3.20.20.450 990 1249 2.4E-100 T 28-03-2018 IPR001633 EAL domain MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 SMART SM00091 405 472 2.3E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 SMART SM00091 695 761 3.4E-4 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 SMART SM00065 543 695 1.7E-8 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 SUPERFAMILY SSF103190 37 214 2.12E-30 T 28-03-2018 IPR029151 Periplasmic sensor domain-like MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 SMART SM00086 479 521 0.26 T 28-03-2018 IPR001610 PAC motif MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 SMART SM00086 767 809 0.002 T 28-03-2018 IPR001610 PAC motif MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 SUPERFAMILY SSF55785 396 519 1.52E-19 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 Gene3D G3DSA:3.30.70.270 821 989 1.5E-64 T 28-03-2018 MKLM6_RS03955 2cd0d6d7ab01f86bfd3fe92282b238cb 1249 SUPERFAMILY SSF55785 701 807 8.38E-26 T 28-03-2018 IPR000014 PAS domain MKLM6_RS20345 d07872b7b6aae4021d478deb6d80dd82 250 Pfam PF04896 Ammonia monooxygenase/methane monooxygenase, subunit C 9 247 9.3E-120 T 28-03-2018 IPR006980 Ammonia monooxygenase/particulate methane monooxygenase, subunit C MKLM6_RS20345 d07872b7b6aae4021d478deb6d80dd82 250 TIGRFAM TIGR03078 CH4_NH3mon_ox_C: methane monooxygenase/ammonia monooxygenase, subunit C 16 235 1.2E-107 T 28-03-2018 IPR006980 Ammonia monooxygenase/particulate methane monooxygenase, subunit C MKLM6_RS20345 d07872b7b6aae4021d478deb6d80dd82 250 Gene3D G3DSA:1.20.1050.50 5 248 1.2E-93 T 28-03-2018 MKLM6_RS11725 9925fc85198cec300ac1ae99c9992557 135 SUPERFAMILY SSF46955 4 116 4.4E-33 T 28-03-2018 IPR009061 Putative DNA-binding domain MKLM6_RS11725 9925fc85198cec300ac1ae99c9992557 135 Pfam PF00376 MerR family regulatory protein 5 42 6.9E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MKLM6_RS11725 9925fc85198cec300ac1ae99c9992557 135 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 40 60 2.3E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MKLM6_RS11725 9925fc85198cec300ac1ae99c9992557 135 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 5 16 2.3E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MKLM6_RS11725 9925fc85198cec300ac1ae99c9992557 135 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 2.3E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MKLM6_RS11725 9925fc85198cec300ac1ae99c9992557 135 Gene3D G3DSA:1.10.1660.10 2 59 3.2E-22 T 28-03-2018 MKLM6_RS11725 9925fc85198cec300ac1ae99c9992557 135 SMART SM00422 4 73 1.1E-26 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MKLM6_RS11725 9925fc85198cec300ac1ae99c9992557 135 Pfam PF09278 MerR, DNA binding 47 108 3.0E-19 T 28-03-2018 IPR015358 Transcription regulator MerR, DNA binding MKLM6_RS11725 9925fc85198cec300ac1ae99c9992557 135 Gene3D G3DSA:1.10.1660.10 60 135 4.6E-20 T 28-03-2018 MKLM6_RS11725 9925fc85198cec300ac1ae99c9992557 135 ProSitePatterns PS00552 MerR-type HTH domain signature. 7 29 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MKLM6_RS21620 ccff09ee6bbebfacdefdb1fef148a2a3 586 Pfam PF05746 DALR anticodon binding domain 465 586 5.0E-34 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MKLM6_RS21620 ccff09ee6bbebfacdefdb1fef148a2a3 586 PRINTS PR01038 Arginyl-tRNA synthetase signature 135 151 4.5E-21 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MKLM6_RS21620 ccff09ee6bbebfacdefdb1fef148a2a3 586 PRINTS PR01038 Arginyl-tRNA synthetase signature 159 172 4.5E-21 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MKLM6_RS21620 ccff09ee6bbebfacdefdb1fef148a2a3 586 PRINTS PR01038 Arginyl-tRNA synthetase signature 120 135 4.5E-21 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MKLM6_RS21620 ccff09ee6bbebfacdefdb1fef148a2a3 586 PRINTS PR01038 Arginyl-tRNA synthetase signature 334 355 4.5E-21 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MKLM6_RS21620 ccff09ee6bbebfacdefdb1fef148a2a3 586 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 28 586 2.2E-135 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MKLM6_RS21620 ccff09ee6bbebfacdefdb1fef148a2a3 586 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 130 139 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS21620 ccff09ee6bbebfacdefdb1fef148a2a3 586 Gene3D G3DSA:1.10.730.10 431 586 5.2E-43 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS21620 ccff09ee6bbebfacdefdb1fef148a2a3 586 Gene3D G3DSA:3.30.1360.70 1 103 6.5E-32 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MKLM6_RS21620 ccff09ee6bbebfacdefdb1fef148a2a3 586 SUPERFAMILY SSF47323 460 586 3.27E-36 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS21620 ccff09ee6bbebfacdefdb1fef148a2a3 586 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 5 91 1.9E-26 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MKLM6_RS21620 ccff09ee6bbebfacdefdb1fef148a2a3 586 SUPERFAMILY SSF55190 28 111 5.1E-27 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MKLM6_RS21620 ccff09ee6bbebfacdefdb1fef148a2a3 586 SMART SM01016 3 91 5.1E-39 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MKLM6_RS21620 ccff09ee6bbebfacdefdb1fef148a2a3 586 Pfam PF00750 tRNA synthetases class I (R) 295 434 1.2E-10 T 28-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 MKLM6_RS21620 ccff09ee6bbebfacdefdb1fef148a2a3 586 Pfam PF00750 tRNA synthetases class I (R) 102 178 6.4E-11 T 28-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 MKLM6_RS21620 ccff09ee6bbebfacdefdb1fef148a2a3 586 SUPERFAMILY SSF52374 115 476 3.94E-84 T 28-03-2018 MKLM6_RS21620 ccff09ee6bbebfacdefdb1fef148a2a3 586 Gene3D G3DSA:3.40.50.620 104 392 4.4E-52 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS21620 ccff09ee6bbebfacdefdb1fef148a2a3 586 SMART SM00836 465 586 1.7E-52 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MKLM6_RS21620 ccff09ee6bbebfacdefdb1fef148a2a3 586 Hamap MF_00123 Arginine--tRNA ligase [argS]. 3 586 26.036 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MKLM6_RS22445 aa88a06fefd55961ebf15df45e7f7dc6 849 Gene3D G3DSA:2.60.40.10 704 797 2.0E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS22445 aa88a06fefd55961ebf15df45e7f7dc6 849 ProSitePatterns PS00018 EF-hand calcium-binding domain. 822 834 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site MKLM6_RS22445 aa88a06fefd55961ebf15df45e7f7dc6 849 Gene3D G3DSA:3.40.1850.10 611 703 1.6E-17 T 28-03-2018 MKLM6_RS22445 aa88a06fefd55961ebf15df45e7f7dc6 849 Gene3D G3DSA:3.40.1850.10 513 607 3.3E-15 T 28-03-2018 MKLM6_RS22445 aa88a06fefd55961ebf15df45e7f7dc6 849 Gene3D G3DSA:2.60.500.10 229 325 4.7E-16 T 28-03-2018 MKLM6_RS22445 aa88a06fefd55961ebf15df45e7f7dc6 849 Gene3D G3DSA:2.60.500.10 326 418 7.3E-27 T 28-03-2018 MKLM6_RS22445 aa88a06fefd55961ebf15df45e7f7dc6 849 Gene3D G3DSA:2.60.500.10 419 510 2.2E-27 T 28-03-2018 MKLM6_RS22445 aa88a06fefd55961ebf15df45e7f7dc6 849 SUPERFAMILY SSF49299 506 589 2.75E-6 T 28-03-2018 IPR000601 PKD domain MKLM6_RS11115 5dacf1aaf4b645a7b2edf0262eb38003 107 SUPERFAMILY SSF52821 3 100 1.05E-32 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS11115 5dacf1aaf4b645a7b2edf0262eb38003 107 Pfam PF00581 Rhodanese-like domain 7 97 1.5E-17 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS11115 5dacf1aaf4b645a7b2edf0262eb38003 107 Gene3D G3DSA:3.40.250.10 1 106 1.3E-28 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS11115 5dacf1aaf4b645a7b2edf0262eb38003 107 SMART SM00450 7 102 2.4E-23 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 SUPERFAMILY SSF55785 543 670 5.41E-14 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 SUPERFAMILY SSF47384 807 885 7.06E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1025 1038 3.0E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 PRINTS PR00344 Bacterial sensor protein C-terminal signature 984 994 3.0E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1001 1019 3.0E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 PRINTS PR00344 Bacterial sensor protein C-terminal signature 966 980 3.0E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 Gene3D G3DSA:3.30.450.20 668 817 2.5E-32 T 28-03-2018 MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 Gene3D G3DSA:3.30.450.20 530 667 3.4E-16 T 28-03-2018 MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 SUPERFAMILY SSF55785 669 798 9.83E-30 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 Gene3D G3DSA:1.20.120.160 1208 1320 3.6E-13 T 28-03-2018 MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 SMART SM00388 820 883 2.4E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 SMART SM00448 1062 1176 3.1E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 Pfam PF00672 HAMP domain 367 411 4.1E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 Gene3D G3DSA:1.10.287.130 818 879 6.8E-17 T 28-03-2018 MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 SUPERFAMILY SSF55785 436 546 8.54E-21 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 Gene3D G3DSA:3.30.450.20 414 529 4.0E-19 T 28-03-2018 MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 Pfam PF01627 Hpt domain 1242 1317 1.3E-5 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 Pfam PF00072 Response regulator receiver domain 1064 1176 1.7E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 930 1040 3.1E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 Pfam PF00512 His Kinase A (phospho-acceptor) domain 821 883 1.5E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 SUPERFAMILY SSF55874 872 1040 3.93E-50 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 Pfam PF00989 PAS fold 426 539 7.2E-16 T 28-03-2018 IPR013767 PAS fold GO:0006355 MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 Pfam PF00989 PAS fold 685 797 7.1E-20 T 28-03-2018 IPR013767 PAS fold GO:0006355 MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 SMART SM00304 366 418 2.3E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 SUPERFAMILY SSF47226 1211 1315 1.44E-15 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 SUPERFAMILY SSF47226 1159 1172 1.44E-15 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 424 546 3.3E-20 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 551 678 4.7E-12 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 681 805 7.4E-28 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 SMART SM00086 632 672 7.7 T 28-03-2018 IPR001610 PAC motif MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 SMART SM00086 502 542 11.0 T 28-03-2018 IPR001610 PAC motif MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 SMART SM00086 760 800 0.0027 T 28-03-2018 IPR001610 PAC motif MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 SMART SM00091 425 492 6.0E-8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 SMART SM00091 684 750 6.6E-14 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 SMART SM00091 554 622 11.0 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 SUPERFAMILY SSF158472 369 413 1.31E-6 T 28-03-2018 MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 Gene3D G3DSA:3.40.50.2300 1057 1192 1.8E-37 T 28-03-2018 MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 Pfam PF13188 PAS domain 554 604 1.6E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 SMART SM00387 930 1041 2.6E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 Gene3D G3DSA:3.30.565.10 887 1049 8.3E-51 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS10010 ca00c230282525b9d001afc16ec98d92 1321 SUPERFAMILY SSF52172 1060 1187 2.56E-37 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS01240 3e3d36c919a7a882f8f44d1c041adaec 455 Pfam PF04955 HupE / UreJ protein 44 185 9.8E-43 T 28-03-2018 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 SMART SM00388 677 743 2.5E-22 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 Gene3D G3DSA:3.30.450.20 368 544 1.8E-38 T 28-03-2018 MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 Gene3D G3DSA:1.20.120.160 1035 1234 6.0E-15 T 28-03-2018 MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 SUPERFAMILY SSF52172 926 1047 8.82E-33 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 SMART SM00387 790 903 4.2E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 SUPERFAMILY SSF158472 332 380 3.4E-10 T 28-03-2018 MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 SMART SM00091 540 606 6.4E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 SMART SM00091 401 469 0.0011 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 SUPERFAMILY SSF55874 732 899 1.83E-45 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 Pfam PF01627 Hpt domain 1098 1176 1.5E-9 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 Gene3D G3DSA:3.30.565.10 747 910 1.1E-47 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 543 664 5.1E-27 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 397 524 1.3E-17 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 Pfam PF08447 PAS fold 425 510 2.9E-24 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 Pfam PF00072 Response regulator receiver domain 930 1042 2.8E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 SUPERFAMILY SSF55785 552 666 2.39E-29 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 SMART SM00448 928 1043 2.4E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 SUPERFAMILY SSF47226 1091 1218 2.57E-15 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 SUPERFAMILY SSF55785 409 520 7.41E-29 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 Pfam PF00989 PAS fold 541 654 4.7E-15 T 28-03-2018 IPR013767 PAS fold GO:0006355 MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 Gene3D G3DSA:1.10.287.130 681 739 1.5E-18 T 28-03-2018 MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 PRINTS PR00344 Bacterial sensor protein C-terminal signature 828 842 9.1E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 PRINTS PR00344 Bacterial sensor protein C-terminal signature 846 856 9.1E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 PRINTS PR00344 Bacterial sensor protein C-terminal signature 863 881 9.1E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 PRINTS PR00344 Bacterial sensor protein C-terminal signature 887 900 9.1E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 Gene3D G3DSA:3.40.50.2300 919 1034 8.0E-36 T 28-03-2018 MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 SMART SM00086 616 657 42.0 T 28-03-2018 IPR001610 PAC motif MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 SMART SM00086 475 517 1.3E-13 T 28-03-2018 IPR001610 PAC motif MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 SUPERFAMILY SSF47384 662 744 4.12E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 Pfam PF00512 His Kinase A (phospho-acceptor) domain 678 743 8.7E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 Pfam PF00672 HAMP domain 331 379 1.0E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 Gene3D G3DSA:3.30.450.20 553 680 6.6E-25 T 28-03-2018 MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 SMART SM00304 331 383 1.3E-14 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 Gene3D G3DSA:3.30.450.20 206 310 0.0015 T 28-03-2018 MKLM6_RS11850 5ed090069e748fb8307a24ef75b87f68 1270 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 790 902 2.3E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS04745 e658ab9d05d9b7de773b464dae988118 717 Gene3D G3DSA:3.40.1110.10 325 477 1.4E-18 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MKLM6_RS04745 e658ab9d05d9b7de773b464dae988118 717 Gene3D G3DSA:1.20.1110.10 31 324 4.7E-24 T 28-03-2018 MKLM6_RS04745 e658ab9d05d9b7de773b464dae988118 717 Pfam PF00122 E1-E2 ATPase 119 293 1.0E-30 T 28-03-2018 MKLM6_RS04745 e658ab9d05d9b7de773b464dae988118 717 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 74 340 2.5E-29 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS04745 e658ab9d05d9b7de773b464dae988118 717 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 451 634 3.0E-43 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MKLM6_RS04745 e658ab9d05d9b7de773b464dae988118 717 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 315 321 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MKLM6_RS04745 e658ab9d05d9b7de773b464dae988118 717 Gene3D G3DSA:3.40.50.1000 478 609 4.5E-32 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS04745 e658ab9d05d9b7de773b464dae988118 717 SUPERFAMILY SSF81665 210 307 3.27E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS04745 e658ab9d05d9b7de773b464dae988118 717 SUPERFAMILY SSF81665 31 105 3.27E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MKLM6_RS04745 e658ab9d05d9b7de773b464dae988118 717 Pfam PF00702 haloacid dehalogenase-like hydrolase 309 565 1.8E-31 T 28-03-2018 MKLM6_RS04745 e658ab9d05d9b7de773b464dae988118 717 SUPERFAMILY SSF81653 120 209 2.09E-19 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MKLM6_RS04745 e658ab9d05d9b7de773b464dae988118 717 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 10 715 41.153 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 MKLM6_RS04745 e658ab9d05d9b7de773b464dae988118 717 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 8 399 5.6E-174 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 MKLM6_RS04745 e658ab9d05d9b7de773b464dae988118 717 SUPERFAMILY SSF56784 470 594 4.04E-36 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS04745 e658ab9d05d9b7de773b464dae988118 717 SUPERFAMILY SSF56784 383 439 4.04E-36 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS04745 e658ab9d05d9b7de773b464dae988118 717 SUPERFAMILY SSF56784 301 325 4.04E-36 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS04745 e658ab9d05d9b7de773b464dae988118 717 SUPERFAMILY SSF81660 426 485 5.89E-30 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MKLM6_RS04745 e658ab9d05d9b7de773b464dae988118 717 SUPERFAMILY SSF81660 324 398 5.89E-30 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MKLM6_RS04745 e658ab9d05d9b7de773b464dae988118 717 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 574 586 4.4E-24 T 28-03-2018 MKLM6_RS04745 e658ab9d05d9b7de773b464dae988118 717 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 156 170 4.4E-24 T 28-03-2018 MKLM6_RS04745 e658ab9d05d9b7de773b464dae988118 717 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 313 327 4.4E-24 T 28-03-2018 MKLM6_RS04745 e658ab9d05d9b7de773b464dae988118 717 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 551 570 4.4E-24 T 28-03-2018 MKLM6_RS04745 e658ab9d05d9b7de773b464dae988118 717 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 498 508 4.4E-24 T 28-03-2018 MKLM6_RS10895 cef104facfc2d9b02c081e7cb301efcb 176 SUPERFAMILY SSF52833 38 171 3.93E-38 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS10895 cef104facfc2d9b02c081e7cb301efcb 176 Pfam PF08534 Redoxin 35 157 6.4E-20 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 MKLM6_RS10895 cef104facfc2d9b02c081e7cb301efcb 176 ProSitePatterns PS00194 Thioredoxin family active site. 63 81 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MKLM6_RS10895 cef104facfc2d9b02c081e7cb301efcb 176 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 4 169 4.5E-54 T 28-03-2018 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 MKLM6_RS10895 cef104facfc2d9b02c081e7cb301efcb 176 Gene3D G3DSA:3.40.30.10 25 174 4.0E-32 T 28-03-2018 MKLM6_RS04000 63453a2a52021bb3b6f64f11f309e6ca 617 SUPERFAMILY SSF50998 34 614 7.72E-168 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MKLM6_RS04000 63453a2a52021bb3b6f64f11f309e6ca 617 Gene3D G3DSA:2.140.10.10 27 617 1.4E-121 T 28-03-2018 MKLM6_RS04000 63453a2a52021bb3b6f64f11f309e6ca 617 Pfam PF01011 PQQ enzyme repeat 482 510 1.8E-4 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat MKLM6_RS04000 63453a2a52021bb3b6f64f11f309e6ca 617 Pfam PF01011 PQQ enzyme repeat 515 547 1.6E-7 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat MKLM6_RS04000 63453a2a52021bb3b6f64f11f309e6ca 617 Pfam PF13360 PQQ-like domain 70 218 9.6E-18 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat MKLM6_RS04000 63453a2a52021bb3b6f64f11f309e6ca 617 TIGRFAM TIGR03075 PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family 23 569 1.6E-227 T 28-03-2018 IPR017512 PQQ-dependent dehydrogenase, methanol/ethanol family GO:0005509|GO:0016020|GO:0016614|GO:0055114 MKLM6_RS04000 63453a2a52021bb3b6f64f11f309e6ca 617 SMART SM00564 84 116 17.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MKLM6_RS04000 63453a2a52021bb3b6f64f11f309e6ca 617 SMART SM00564 182 219 29.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MKLM6_RS04000 63453a2a52021bb3b6f64f11f309e6ca 617 SMART SM00564 465 500 13.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MKLM6_RS04000 63453a2a52021bb3b6f64f11f309e6ca 617 SMART SM00564 509 541 3.2E-5 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MKLM6_RS04000 63453a2a52021bb3b6f64f11f309e6ca 617 SMART SM00564 272 319 3.4 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MKLM6_RS04000 63453a2a52021bb3b6f64f11f309e6ca 617 SMART SM00564 136 168 0.11 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MKLM6_RS04000 63453a2a52021bb3b6f64f11f309e6ca 617 ProSitePatterns PS00364 Bacterial quinoprotein dehydrogenases signature 2. 267 288 - T 28-03-2018 IPR001479 Quinoprotein dehydrogenase, conserved site GO:0030288|GO:0055114 MKLM6_RS12385 05122cc92478f3cdf620a2f19f225e05 421 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 9 420 37.231 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MKLM6_RS12385 05122cc92478f3cdf620a2f19f225e05 421 Pfam PF00171 Aldehyde dehydrogenase family 7 289 4.5E-15 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MKLM6_RS12385 05122cc92478f3cdf620a2f19f225e05 421 Pfam PF00171 Aldehyde dehydrogenase family 313 375 1.2E-6 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MKLM6_RS12385 05122cc92478f3cdf620a2f19f225e05 421 Gene3D G3DSA:3.40.605.10 2 240 1.7E-40 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MKLM6_RS12385 05122cc92478f3cdf620a2f19f225e05 421 Gene3D G3DSA:3.40.605.10 241 421 1.6E-35 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MKLM6_RS12385 05122cc92478f3cdf620a2f19f225e05 421 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 327 348 - T 28-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MKLM6_RS12385 05122cc92478f3cdf620a2f19f225e05 421 SUPERFAMILY SSF53720 10 420 3.14E-107 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MKLM6_RS12385 05122cc92478f3cdf620a2f19f225e05 421 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 18 410 2.5E-131 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MKLM6_RS12385 05122cc92478f3cdf620a2f19f225e05 421 PIRSF PIRSF000151 3 421 1.3E-157 T 28-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 MKLM6_RS14770 357c92d9f7e3ae808bfa132e0e43025d 145 Gene3D G3DSA:3.90.79.10 3 134 1.7E-31 T 28-03-2018 MKLM6_RS14770 357c92d9f7e3ae808bfa132e0e43025d 145 SUPERFAMILY SSF55811 6 135 8.12E-29 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MKLM6_RS14770 357c92d9f7e3ae808bfa132e0e43025d 145 PRINTS PR00502 NUDIX hydrolase family signature 37 51 1.4E-8 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MKLM6_RS14770 357c92d9f7e3ae808bfa132e0e43025d 145 PRINTS PR00502 NUDIX hydrolase family signature 51 66 1.4E-8 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MKLM6_RS14770 357c92d9f7e3ae808bfa132e0e43025d 145 Pfam PF00293 NUDIX domain 21 130 1.5E-20 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MKLM6_RS14770 357c92d9f7e3ae808bfa132e0e43025d 145 ProSitePatterns PS00893 Nudix box signature. 42 63 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MKLM6_RS13235 0906de42e9b0e1b4ed4ce31eb8a8a03e 247 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 226 40.344 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS13235 0906de42e9b0e1b4ed4ce31eb8a8a03e 247 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 159 183 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 MKLM6_RS13235 0906de42e9b0e1b4ed4ce31eb8a8a03e 247 Pfam PF00318 Ribosomal protein S2 9 225 2.2E-93 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS13235 0906de42e9b0e1b4ed4ce31eb8a8a03e 247 SUPERFAMILY SSF52313 6 231 7.19E-91 T 28-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain MKLM6_RS13235 0906de42e9b0e1b4ed4ce31eb8a8a03e 247 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 4 227 2.4E-101 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS13235 0906de42e9b0e1b4ed4ce31eb8a8a03e 247 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 MKLM6_RS13235 0906de42e9b0e1b4ed4ce31eb8a8a03e 247 PRINTS PR00395 Ribosomal protein S2 signature 159 176 4.1E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS13235 0906de42e9b0e1b4ed4ce31eb8a8a03e 247 PRINTS PR00395 Ribosomal protein S2 signature 6 24 4.1E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS13235 0906de42e9b0e1b4ed4ce31eb8a8a03e 247 PRINTS PR00395 Ribosomal protein S2 signature 37 46 4.1E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS13235 0906de42e9b0e1b4ed4ce31eb8a8a03e 247 PRINTS PR00395 Ribosomal protein S2 signature 176 187 4.1E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS13235 0906de42e9b0e1b4ed4ce31eb8a8a03e 247 PRINTS PR00395 Ribosomal protein S2 signature 87 104 4.1E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS13235 0906de42e9b0e1b4ed4ce31eb8a8a03e 247 PRINTS PR00395 Ribosomal protein S2 signature 197 211 4.1E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS13235 0906de42e9b0e1b4ed4ce31eb8a8a03e 247 Gene3D G3DSA:3.40.50.10490 5 246 3.0E-93 T 28-03-2018 MKLM6_RS06965 4a067b9d584c3e15c9f8f2d569313edf 720 Pfam PF00580 UvrD/REP helicase N-terminal domain 10 271 1.7E-77 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MKLM6_RS06965 4a067b9d584c3e15c9f8f2d569313edf 720 Gene3D G3DSA:3.40.50.300 3 149 2.7E-29 T 28-03-2018 MKLM6_RS06965 4a067b9d584c3e15c9f8f2d569313edf 720 Gene3D G3DSA:3.40.50.300 150 281 1.4E-30 T 28-03-2018 MKLM6_RS06965 4a067b9d584c3e15c9f8f2d569313edf 720 SUPERFAMILY SSF52540 5 643 3.4E-172 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS06965 4a067b9d584c3e15c9f8f2d569313edf 720 Gene3D G3DSA:3.40.50.300 383 659 2.1E-49 T 28-03-2018 MKLM6_RS06965 4a067b9d584c3e15c9f8f2d569313edf 720 Gene3D G3DSA:3.40.50.300 282 382 4.1E-25 T 28-03-2018 MKLM6_RS06965 4a067b9d584c3e15c9f8f2d569313edf 720 Pfam PF13361 UvrD-like helicase C-terminal domain 277 617 3.6E-70 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MKLM6_RS15885 ce6fee2d680b975e43b26616fe54efde 298 Gene3D G3DSA:3.40.50.720 2 171 7.4E-22 T 28-03-2018 MKLM6_RS15885 ce6fee2d680b975e43b26616fe54efde 298 SUPERFAMILY SSF51735 2 296 3.1E-103 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS15885 ce6fee2d680b975e43b26616fe54efde 298 Gene3D G3DSA:3.90.25.10 172 203 1.1E-7 T 28-03-2018 MKLM6_RS15885 ce6fee2d680b975e43b26616fe54efde 298 Pfam PF04321 RmlD substrate binding domain 2 295 1.2E-108 T 28-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 MKLM6_RS15885 ce6fee2d680b975e43b26616fe54efde 298 Gene3D G3DSA:3.90.25.10 204 282 2.0E-22 T 28-03-2018 MKLM6_RS15885 ce6fee2d680b975e43b26616fe54efde 298 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 294 8.3E-100 T 28-03-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 MKLM6_RS22675 aa7cbea96b360f9e0edc96b7b0cea80b 291 Pfam PF03466 LysR substrate binding domain 93 288 2.1E-36 T 28-03-2018 IPR005119 LysR, substrate-binding MKLM6_RS22675 aa7cbea96b360f9e0edc96b7b0cea80b 291 SUPERFAMILY SSF53850 93 287 5.43E-32 T 28-03-2018 MKLM6_RS22675 aa7cbea96b360f9e0edc96b7b0cea80b 291 Gene3D G3DSA:3.40.190.10 89 176 6.3E-17 T 28-03-2018 MKLM6_RS22675 aa7cbea96b360f9e0edc96b7b0cea80b 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.3E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS22675 aa7cbea96b360f9e0edc96b7b0cea80b 291 SUPERFAMILY SSF46785 3 110 1.31E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS22675 aa7cbea96b360f9e0edc96b7b0cea80b 291 Gene3D G3DSA:3.40.190.10 177 261 1.5E-15 T 28-03-2018 MKLM6_RS22675 aa7cbea96b360f9e0edc96b7b0cea80b 291 Gene3D G3DSA:1.10.10.10 1 83 1.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS22675 aa7cbea96b360f9e0edc96b7b0cea80b 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.2E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS22675 aa7cbea96b360f9e0edc96b7b0cea80b 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.2E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS22675 aa7cbea96b360f9e0edc96b7b0cea80b 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.2E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS01355 1f63f501e921ff8e5c149ebcfdeef5c3 221 Pfam PF00072 Response regulator receiver domain 4 112 4.3E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS01355 1f63f501e921ff8e5c149ebcfdeef5c3 221 Gene3D G3DSA:3.40.50.2300 1 129 2.5E-30 T 28-03-2018 MKLM6_RS01355 1f63f501e921ff8e5c149ebcfdeef5c3 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 217 7.8E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS01355 1f63f501e921ff8e5c149ebcfdeef5c3 221 Gene3D G3DSA:1.10.10.10 130 221 5.0E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS01355 1f63f501e921ff8e5c149ebcfdeef5c3 221 SUPERFAMILY SSF46894 121 217 1.33E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MKLM6_RS01355 1f63f501e921ff8e5c149ebcfdeef5c3 221 SUPERFAMILY SSF52172 1 118 1.14E-34 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS01355 1f63f501e921ff8e5c149ebcfdeef5c3 221 SMART SM00862 146 217 5.0E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS01355 1f63f501e921ff8e5c149ebcfdeef5c3 221 SMART SM00448 1 112 2.0E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS16445 6f4e2291d866ace9ee47bbbad9b70807 581 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 577 7.2E-236 T 28-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MKLM6_RS16445 6f4e2291d866ace9ee47bbbad9b70807 581 PIRSF PIRSF001535 1 581 7.1E-264 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MKLM6_RS16445 6f4e2291d866ace9ee47bbbad9b70807 581 SUPERFAMILY SSF52954 474 580 6.8E-32 T 28-03-2018 IPR004154 Anticodon-binding MKLM6_RS16445 6f4e2291d866ace9ee47bbbad9b70807 581 Gene3D G3DSA:3.40.50.800 468 581 3.3E-30 T 28-03-2018 IPR004154 Anticodon-binding MKLM6_RS16445 6f4e2291d866ace9ee47bbbad9b70807 581 Gene3D G3DSA:3.30.930.10 393 467 7.7E-11 T 28-03-2018 MKLM6_RS16445 6f4e2291d866ace9ee47bbbad9b70807 581 Gene3D G3DSA:3.30.930.10 23 261 3.5E-70 T 28-03-2018 MKLM6_RS16445 6f4e2291d866ace9ee47bbbad9b70807 581 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 8.6E-20 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MKLM6_RS16445 6f4e2291d866ace9ee47bbbad9b70807 581 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 8.6E-20 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MKLM6_RS16445 6f4e2291d866ace9ee47bbbad9b70807 581 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 8.6E-20 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MKLM6_RS16445 6f4e2291d866ace9ee47bbbad9b70807 581 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 8.6E-20 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MKLM6_RS16445 6f4e2291d866ace9ee47bbbad9b70807 581 Gene3D G3DSA:3.90.960.10 262 392 1.1E-29 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MKLM6_RS16445 6f4e2291d866ace9ee47bbbad9b70807 581 SUPERFAMILY SSF55826 218 397 9.29E-28 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MKLM6_RS16445 6f4e2291d866ace9ee47bbbad9b70807 581 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 581 41.763 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MKLM6_RS16445 6f4e2291d866ace9ee47bbbad9b70807 581 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 468 1.9E-47 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS16445 6f4e2291d866ace9ee47bbbad9b70807 581 Pfam PF04073 Aminoacyl-tRNA editing domain 257 384 6.9E-27 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MKLM6_RS16445 6f4e2291d866ace9ee47bbbad9b70807 581 SUPERFAMILY SSF55681 417 488 1.32E-107 T 28-03-2018 MKLM6_RS16445 6f4e2291d866ace9ee47bbbad9b70807 581 SUPERFAMILY SSF55681 10 237 1.32E-107 T 28-03-2018 MKLM6_RS16445 6f4e2291d866ace9ee47bbbad9b70807 581 Pfam PF03129 Anticodon binding domain 485 578 3.7E-21 T 28-03-2018 IPR004154 Anticodon-binding MKLM6_RS00425 f5685d24d9924e3604175916e421d3b6 365 Pfam PF01609 Transposase DDE domain 199 346 8.4E-14 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS00425 f5685d24d9924e3604175916e421d3b6 365 Pfam PF05598 Transposase domain (DUF772) 53 128 1.7E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS13165 2e8d64372030b98fbc938eb39758d07c 324 SUPERFAMILY SSF56349 62 291 3.24E-23 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS13165 2e8d64372030b98fbc938eb39758d07c 324 Gene3D G3DSA:1.10.150.130 55 170 1.4E-6 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal MKLM6_RS13165 2e8d64372030b98fbc938eb39758d07c 324 Gene3D G3DSA:1.10.443.10 176 305 6.2E-11 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS13060 81261d74dd77421114af17e181554064 554 SUPERFAMILY SSF52374 17 339 6.26E-97 T 28-03-2018 MKLM6_RS13060 81261d74dd77421114af17e181554064 554 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 342 530 5.6E-61 T 28-03-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MKLM6_RS13060 81261d74dd77421114af17e181554064 554 Gene3D G3DSA:3.40.50.620 26 164 8.5E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS13060 81261d74dd77421114af17e181554064 554 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 30 339 1.6E-111 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 MKLM6_RS13060 81261d74dd77421114af17e181554064 554 Gene3D G3DSA:2.40.240.10 466 550 7.1E-30 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MKLM6_RS13060 81261d74dd77421114af17e181554064 554 Gene3D G3DSA:1.10.1160.10 263 340 7.7E-35 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 MKLM6_RS13060 81261d74dd77421114af17e181554064 554 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 31 554 9.0E-237 T 28-03-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MKLM6_RS13060 81261d74dd77421114af17e181554064 554 Gene3D G3DSA:2.40.240.10 346 465 5.7E-49 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MKLM6_RS13060 81261d74dd77421114af17e181554064 554 PRINTS PR00987 Glutamyl-tRNA synthetase signature 63 76 9.5E-8 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MKLM6_RS13060 81261d74dd77421114af17e181554064 554 PRINTS PR00987 Glutamyl-tRNA synthetase signature 212 222 9.5E-8 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MKLM6_RS13060 81261d74dd77421114af17e181554064 554 PRINTS PR00987 Glutamyl-tRNA synthetase signature 34 46 9.5E-8 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MKLM6_RS13060 81261d74dd77421114af17e181554064 554 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 37 48 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS13060 81261d74dd77421114af17e181554064 554 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 552 52.648 T 28-03-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 MKLM6_RS13060 81261d74dd77421114af17e181554064 554 Gene3D G3DSA:3.40.50.620 165 262 3.0E-23 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS13060 81261d74dd77421114af17e181554064 554 SUPERFAMILY SSF50715 342 551 9.42E-74 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MKLM6_RS14000 a1c55f9112ae5574d2dbec3b42d6df8b 481 Pfam PF03600 Citrate transporter 52 426 6.1E-41 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 MKLM6_RS20965 7896c2094bd088a854a7cd507d1a2f34 847 Pfam PF07715 TonB-dependent Receptor Plug Domain 168 265 4.3E-18 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS20965 7896c2094bd088a854a7cd507d1a2f34 847 SMART SM00965 65 116 4.0E-14 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MKLM6_RS20965 7896c2094bd088a854a7cd507d1a2f34 847 SUPERFAMILY SSF56935 123 847 4.51E-131 T 28-03-2018 MKLM6_RS20965 7896c2094bd088a854a7cd507d1a2f34 847 Pfam PF00593 TonB dependent receptor 339 836 3.9E-57 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS20965 7896c2094bd088a854a7cd507d1a2f34 847 Gene3D G3DSA:2.170.130.10 121 278 4.6E-28 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS20965 7896c2094bd088a854a7cd507d1a2f34 847 Gene3D G3DSA:2.40.170.20 279 847 2.7E-87 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS20965 7896c2094bd088a854a7cd507d1a2f34 847 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 169 847 2.8E-103 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 MKLM6_RS20965 7896c2094bd088a854a7cd507d1a2f34 847 Pfam PF07660 Secretin and TonB N terminus short domain 65 115 3.8E-11 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MKLM6_RS18185 3dd6ceb448cf54264c99e9a047bad56d 200 Gene3D G3DSA:3.40.30.10 1 97 6.4E-32 T 28-03-2018 MKLM6_RS18185 3dd6ceb448cf54264c99e9a047bad56d 200 Pfam PF00043 Glutathione S-transferase, C-terminal domain 130 189 9.3E-11 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal MKLM6_RS18185 3dd6ceb448cf54264c99e9a047bad56d 200 SUPERFAMILY SSF47616 89 194 1.32E-25 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like MKLM6_RS18185 3dd6ceb448cf54264c99e9a047bad56d 200 SUPERFAMILY SSF52833 1 83 3.01E-27 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS18185 3dd6ceb448cf54264c99e9a047bad56d 200 Gene3D G3DSA:1.20.1050.10 98 187 8.1E-21 T 28-03-2018 MKLM6_RS18185 3dd6ceb448cf54264c99e9a047bad56d 200 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 79 1.1E-17 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MKLM6_RS20225 a5ace0f9c6e745664079581a0c1f8007 216 SUPERFAMILY SSF52833 1 96 1.48E-19 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS20225 a5ace0f9c6e745664079581a0c1f8007 216 SUPERFAMILY SSF47616 74 206 5.01E-19 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like MKLM6_RS20225 a5ace0f9c6e745664079581a0c1f8007 216 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 76 6.7E-17 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MKLM6_RS20225 a5ace0f9c6e745664079581a0c1f8007 216 Pfam PF13410 Glutathione S-transferase, C-terminal domain 121 190 6.3E-10 T 28-03-2018 MKLM6_RS20225 a5ace0f9c6e745664079581a0c1f8007 216 Gene3D G3DSA:3.40.30.10 1 88 7.9E-22 T 28-03-2018 MKLM6_RS20225 a5ace0f9c6e745664079581a0c1f8007 216 Gene3D G3DSA:1.20.1050.10 89 216 1.5E-22 T 28-03-2018 MKLM6_RS17525 1c34ea8e5f23ce99d79437a7265f6ad4 109 Pfam PF12840 Helix-turn-helix domain 9 69 1.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS17525 1c34ea8e5f23ce99d79437a7265f6ad4 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 6.8E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MKLM6_RS17525 1c34ea8e5f23ce99d79437a7265f6ad4 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 6.8E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MKLM6_RS17525 1c34ea8e5f23ce99d79437a7265f6ad4 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 6.8E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MKLM6_RS17525 1c34ea8e5f23ce99d79437a7265f6ad4 109 SUPERFAMILY SSF46785 5 93 1.32E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS17525 1c34ea8e5f23ce99d79437a7265f6ad4 109 Gene3D G3DSA:1.10.10.10 1 90 1.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS17525 1c34ea8e5f23ce99d79437a7265f6ad4 109 SMART SM00418 8 89 4.6E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MKLM6_RS10980 d248abbe5b6384795dda918fa74cf6c4 681 Pfam PF07517 SecA DEAD-like domain 72 452 1.5E-77 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MKLM6_RS10980 d248abbe5b6384795dda918fa74cf6c4 681 SUPERFAMILY SSF52540 419 464 1.39E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS10980 d248abbe5b6384795dda918fa74cf6c4 681 SUPERFAMILY SSF52540 105 284 1.39E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS10980 d248abbe5b6384795dda918fa74cf6c4 681 ProSitePatterns PS01312 SecA family signature. 551 566 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 MKLM6_RS10980 d248abbe5b6384795dda918fa74cf6c4 681 Hamap MF_01382 Protein translocase subunit SecA [secA]. 35 681 11.231 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MKLM6_RS10980 d248abbe5b6384795dda918fa74cf6c4 681 SMART SM00957 47 453 4.1E-100 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MKLM6_RS10980 d248abbe5b6384795dda918fa74cf6c4 681 Gene3D G3DSA:3.40.50.300 62 298 1.8E-32 T 28-03-2018 MKLM6_RS10980 d248abbe5b6384795dda918fa74cf6c4 681 SMART SM00958 288 409 6.9E-17 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 MKLM6_RS10980 d248abbe5b6384795dda918fa74cf6c4 681 SUPERFAMILY SSF52540 467 624 3.27E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS10980 d248abbe5b6384795dda918fa74cf6c4 681 Gene3D G3DSA:3.40.50.300 468 675 1.9E-31 T 28-03-2018 MKLM6_RS10980 d248abbe5b6384795dda918fa74cf6c4 681 PRINTS PR00906 SecA protein signature 427 444 3.0E-35 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MKLM6_RS10980 d248abbe5b6384795dda918fa74cf6c4 681 PRINTS PR00906 SecA protein signature 138 152 3.0E-35 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MKLM6_RS10980 d248abbe5b6384795dda918fa74cf6c4 681 PRINTS PR00906 SecA protein signature 390 412 3.0E-35 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MKLM6_RS10980 d248abbe5b6384795dda918fa74cf6c4 681 PRINTS PR00906 SecA protein signature 464 477 3.0E-35 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MKLM6_RS10980 d248abbe5b6384795dda918fa74cf6c4 681 PRINTS PR00906 SecA protein signature 100 124 3.0E-35 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MKLM6_RS10980 d248abbe5b6384795dda918fa74cf6c4 681 PRINTS PR00906 SecA protein signature 154 164 3.0E-35 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MKLM6_RS10980 d248abbe5b6384795dda918fa74cf6c4 681 PRINTS PR00906 SecA protein signature 207 227 3.0E-35 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MKLM6_RS10980 d248abbe5b6384795dda918fa74cf6c4 681 Gene3D G3DSA:3.90.1440.10 299 418 2.2E-26 T 28-03-2018 MKLM6_RS10980 d248abbe5b6384795dda918fa74cf6c4 681 SUPERFAMILY SSF81767 292 416 3.66E-26 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 MKLM6_RS10980 d248abbe5b6384795dda918fa74cf6c4 681 Pfam PF01043 SecA preprotein cross-linking domain 292 409 1.1E-22 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 MKLM6_RS01715 b01de14889a0006210224f6b13115e03 1223 SUPERFAMILY SSF82282 6 398 3.01E-114 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 MKLM6_RS01715 b01de14889a0006210224f6b13115e03 1223 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 936 1207 1.2E-128 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MKLM6_RS01715 b01de14889a0006210224f6b13115e03 1223 Gene3D G3DSA:3.20.20.20 344 643 6.3E-76 T 28-03-2018 MKLM6_RS01715 b01de14889a0006210224f6b13115e03 1223 Pfam PF02607 B12 binding domain 657 729 2.9E-24 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MKLM6_RS01715 b01de14889a0006210224f6b13115e03 1223 Gene3D G3DSA:3.20.20.330 1 337 9.4E-111 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 MKLM6_RS01715 b01de14889a0006210224f6b13115e03 1223 SUPERFAMILY SSF56507 904 1222 5.89E-129 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MKLM6_RS01715 b01de14889a0006210224f6b13115e03 1223 Gene3D G3DSA:3.40.50.280 742 894 1.1E-55 T 28-03-2018 MKLM6_RS01715 b01de14889a0006210224f6b13115e03 1223 Pfam PF02310 B12 binding domain 747 837 1.9E-19 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MKLM6_RS01715 b01de14889a0006210224f6b13115e03 1223 Gene3D G3DSA:1.10.1240.10 649 734 8.7E-37 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MKLM6_RS01715 b01de14889a0006210224f6b13115e03 1223 SUPERFAMILY SSF51717 355 629 1.31E-90 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MKLM6_RS01715 b01de14889a0006210224f6b13115e03 1223 Pfam PF02574 Homocysteine S-methyltransferase 16 323 5.1E-78 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 MKLM6_RS01715 b01de14889a0006210224f6b13115e03 1223 SMART SM01018 654 737 6.4E-44 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MKLM6_RS01715 b01de14889a0006210224f6b13115e03 1223 Gene3D G3DSA:3.10.196.10 954 1076 4.2E-51 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MKLM6_RS01715 b01de14889a0006210224f6b13115e03 1223 Gene3D G3DSA:3.10.196.10 1077 1223 7.9E-60 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MKLM6_RS01715 b01de14889a0006210224f6b13115e03 1223 SUPERFAMILY SSF47644 650 736 2.09E-28 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MKLM6_RS01715 b01de14889a0006210224f6b13115e03 1223 TIGRFAM TIGR02082 metH: methionine synthase 11 1191 0.0 T 28-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MKLM6_RS01715 b01de14889a0006210224f6b13115e03 1223 Pfam PF00809 Pterin binding enzyme 359 597 2.8E-62 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MKLM6_RS01715 b01de14889a0006210224f6b13115e03 1223 SUPERFAMILY SSF52242 743 893 1.13E-45 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MKLM6_RS01715 b01de14889a0006210224f6b13115e03 1223 PIRSF PIRSF000381 1 1194 0.0 T 28-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MKLM6_RS19990 2559eac50cc66dffaf83a73e21a779a0 534 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 11 516 42.531 T 28-03-2018 IPR003846 Uncharacterised protein family UPF0061 MKLM6_RS19990 2559eac50cc66dffaf83a73e21a779a0 534 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 38 499 1.3E-135 T 28-03-2018 IPR003846 Uncharacterised protein family UPF0061 MKLM6_RS13040 b67e60d551611f0152c2c67b1b628a90 159 Gene3D G3DSA:1.10.443.10 60 157 5.3E-7 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS13040 b67e60d551611f0152c2c67b1b628a90 159 SUPERFAMILY SSF56349 7 141 1.56E-21 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS13040 b67e60d551611f0152c2c67b1b628a90 159 Gene3D G3DSA:1.10.150.130 1 59 1.7E-5 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal MKLM6_RS19515 be914e2e62e2875f286140c2a52350cb 296 Gene3D G3DSA:3.40.50.300 71 229 4.9E-24 T 28-03-2018 MKLM6_RS19515 be914e2e62e2875f286140c2a52350cb 296 Gene3D G3DSA:2.40.50.140 1 60 2.3E-10 T 28-03-2018 MKLM6_RS19515 be914e2e62e2875f286140c2a52350cb 296 Gene3D G3DSA:1.10.40.50 231 293 2.8E-17 T 28-03-2018 MKLM6_RS19515 be914e2e62e2875f286140c2a52350cb 296 Pfam PF03193 RsgA GTPase 58 229 4.2E-50 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 MKLM6_RS19515 be914e2e62e2875f286140c2a52350cb 296 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 5 294 32.569 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 MKLM6_RS19515 be914e2e62e2875f286140c2a52350cb 296 SUPERFAMILY SSF50249 5 62 4.97E-5 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS19515 be914e2e62e2875f286140c2a52350cb 296 SUPERFAMILY SSF52540 72 289 5.53E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS19515 be914e2e62e2875f286140c2a52350cb 296 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 37 287 8.1E-72 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 MKLM6_RS16465 9e741f30f6eb1deb5a59b008097fca2d 165 Pfam PF04390 Lipopolysaccharide-assembly 43 156 3.1E-9 T 28-03-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 MKLM6_RS16465 9e741f30f6eb1deb5a59b008097fca2d 165 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 4 162 20.357 T 28-03-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 MKLM6_RS16465 9e741f30f6eb1deb5a59b008097fca2d 165 Gene3D G3DSA:3.30.160.150 19 165 2.1E-31 T 28-03-2018 MKLM6_RS19155 08613a1d70f630157b53450322506ae1 412 Gene3D G3DSA:2.60.120.570 29 180 1.8E-66 T 28-03-2018 IPR023301 Ammonia/methane monooxygenase, subunitB, N-terminal MKLM6_RS19155 08613a1d70f630157b53450322506ae1 412 Pfam PF04744 Monooxygenase subunit B protein 30 411 4.6E-150 T 28-03-2018 IPR006833 Ammonia monooxygenase/particulate methane monooxygenase, subunit B MKLM6_RS19155 08613a1d70f630157b53450322506ae1 412 Gene3D G3DSA:2.60.40.1580 274 412 6.9E-23 T 28-03-2018 MKLM6_RS19155 08613a1d70f630157b53450322506ae1 412 TIGRFAM TIGR03079 CH4_NH3mon_ox_B: methane monooxygenase/ammonia monooxygenase, subunit B 12 411 4.7E-129 T 28-03-2018 IPR006833 Ammonia monooxygenase/particulate methane monooxygenase, subunit B MKLM6_RS08785 d67137501772c43f05e44b8b2f526684 79 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 61 16.775 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS08785 d67137501772c43f05e44b8b2f526684 79 SUPERFAMILY SSF63562 1 68 2.27E-22 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 MKLM6_RS08785 d67137501772c43f05e44b8b2f526684 79 Gene3D G3DSA:3.90.940.10 1 78 9.0E-23 T 28-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 MKLM6_RS08785 d67137501772c43f05e44b8b2f526684 79 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 58 1.1E-20 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS08785 d67137501772c43f05e44b8b2f526684 79 Pfam PF01192 RNA polymerase Rpb6 8 58 8.3E-15 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 MKLM6_RS08785 d67137501772c43f05e44b8b2f526684 79 SMART SM01409 8 60 3.8E-16 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 MKLM6_RS09750 fd3cff05fea19a1d53395e9c0f4597b3 161 Pfam PF03330 Lytic transglycolase 48 137 7.2E-24 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain MKLM6_RS09750 fd3cff05fea19a1d53395e9c0f4597b3 161 SUPERFAMILY SSF50685 53 136 1.15E-11 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain MKLM6_RS09750 fd3cff05fea19a1d53395e9c0f4597b3 161 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 50 144 1.1E-36 T 28-03-2018 IPR012997 Rare lipoprotein A MKLM6_RS09750 fd3cff05fea19a1d53395e9c0f4597b3 161 Gene3D G3DSA:2.40.40.10 27 140 9.1E-23 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain MKLM6_RS09750 fd3cff05fea19a1d53395e9c0f4597b3 161 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 18 140 20.86 T 28-03-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 MKLM6_RS12120 10510e8f741ddc89310895afb708459e 136 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 30 80 2.0E-5 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12120 10510e8f741ddc89310895afb708459e 136 SUPERFAMILY SSF51344 4 83 8.76E-14 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12120 10510e8f741ddc89310895afb708459e 136 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 12 80 6.1E-14 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12120 10510e8f741ddc89310895afb708459e 136 Gene3D G3DSA:2.60.15.10 1 88 1.4E-13 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12120 10510e8f741ddc89310895afb708459e 136 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 130 11.051 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS15110 766d7c2fcb17be3bfbafdc6bd980f3d0 154 Gene3D G3DSA:1.20.5.420 85 138 1.1E-23 T 28-03-2018 MKLM6_RS15110 766d7c2fcb17be3bfbafdc6bd980f3d0 154 Pfam PF00210 Ferritin-like domain 8 144 4.8E-41 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MKLM6_RS15110 766d7c2fcb17be3bfbafdc6bd980f3d0 154 Gene3D G3DSA:1.20.1260.10 1 77 5.5E-18 T 28-03-2018 IPR012347 Ferritin-related MKLM6_RS15110 766d7c2fcb17be3bfbafdc6bd980f3d0 154 TIGRFAM TIGR00754 bfr: bacterioferritin 1 154 7.7E-78 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MKLM6_RS15110 766d7c2fcb17be3bfbafdc6bd980f3d0 154 SUPERFAMILY SSF47240 1 154 1.48E-57 T 28-03-2018 IPR009078 Ferritin-like superfamily MKLM6_RS15110 766d7c2fcb17be3bfbafdc6bd980f3d0 154 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MKLM6_RS15110 766d7c2fcb17be3bfbafdc6bd980f3d0 154 PIRSF PIRSF002560 1 154 2.3E-74 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MKLM6_RS15110 766d7c2fcb17be3bfbafdc6bd980f3d0 154 PRINTS PR00601 Bacterioferritin signature 23 43 3.9E-74 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MKLM6_RS15110 766d7c2fcb17be3bfbafdc6bd980f3d0 154 PRINTS PR00601 Bacterioferritin signature 107 127 3.9E-74 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MKLM6_RS15110 766d7c2fcb17be3bfbafdc6bd980f3d0 154 PRINTS PR00601 Bacterioferritin signature 65 85 3.9E-74 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MKLM6_RS15110 766d7c2fcb17be3bfbafdc6bd980f3d0 154 PRINTS PR00601 Bacterioferritin signature 44 64 3.9E-74 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MKLM6_RS15110 766d7c2fcb17be3bfbafdc6bd980f3d0 154 PRINTS PR00601 Bacterioferritin signature 86 106 3.9E-74 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MKLM6_RS15110 766d7c2fcb17be3bfbafdc6bd980f3d0 154 PRINTS PR00601 Bacterioferritin signature 3 22 3.9E-74 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MKLM6_RS15110 766d7c2fcb17be3bfbafdc6bd980f3d0 154 PRINTS PR00601 Bacterioferritin signature 128 149 3.9E-74 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MKLM6_RS01890 6e934a0d6c6da37840b27f87e0ff534c 736 Pfam PF03150 Di-haem cytochrome c peroxidase 61 389 4.6E-23 T 28-03-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 MKLM6_RS01890 6e934a0d6c6da37840b27f87e0ff534c 736 Gene3D G3DSA:1.10.760.10 383 687 1.5E-34 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS01890 6e934a0d6c6da37840b27f87e0ff534c 736 SUPERFAMILY SSF46626 591 682 1.21E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS01890 6e934a0d6c6da37840b27f87e0ff534c 736 SUPERFAMILY SSF46626 396 432 1.21E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS01890 6e934a0d6c6da37840b27f87e0ff534c 736 Gene3D G3DSA:1.10.760.10 56 382 1.2E-26 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS01890 6e934a0d6c6da37840b27f87e0ff534c 736 SUPERFAMILY SSF46626 198 218 8.17E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS01890 6e934a0d6c6da37840b27f87e0ff534c 736 SUPERFAMILY SSF46626 55 105 8.17E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS01890 6e934a0d6c6da37840b27f87e0ff534c 736 SUPERFAMILY SSF46626 256 282 8.17E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS05645 d0cfa9a363edcd830e36356690dd5274 365 SUPERFAMILY SSF53383 12 363 1.05E-115 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS05645 d0cfa9a363edcd830e36356690dd5274 365 PIRSF PIRSF000390 1 365 1.6E-110 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MKLM6_RS05645 d0cfa9a363edcd830e36356690dd5274 365 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 14 359 1.1E-127 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MKLM6_RS05645 d0cfa9a363edcd830e36356690dd5274 365 Gene3D G3DSA:3.90.1150.10 238 365 5.3E-38 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS05645 d0cfa9a363edcd830e36356690dd5274 365 Gene3D G3DSA:3.40.640.10 1 237 3.1E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS10125 e26b697d08358c9210ff3be97de44807 158 Gene3D G3DSA:2.40.50.180 26 86 9.8E-17 T 28-03-2018 MKLM6_RS10125 e26b697d08358c9210ff3be97de44807 158 Pfam PF01584 CheW-like domain 9 147 4.6E-34 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS10125 e26b697d08358c9210ff3be97de44807 158 Gene3D G3DSA:2.30.30.40 87 140 6.8E-12 T 28-03-2018 MKLM6_RS10125 e26b697d08358c9210ff3be97de44807 158 SMART SM00260 5 146 1.4E-38 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS10125 e26b697d08358c9210ff3be97de44807 158 SUPERFAMILY SSF50341 4 151 6.28E-37 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS10015 f29282b8340b1ceeff7c4c8bed6883de 302 Gene3D G3DSA:3.40.190.10 90 181 1.1E-21 T 28-03-2018 MKLM6_RS10015 f29282b8340b1ceeff7c4c8bed6883de 302 Pfam PF03466 LysR substrate binding domain 91 294 2.2E-40 T 28-03-2018 IPR005119 LysR, substrate-binding MKLM6_RS10015 f29282b8340b1ceeff7c4c8bed6883de 302 SUPERFAMILY SSF46785 1 113 8.16E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS10015 f29282b8340b1ceeff7c4c8bed6883de 302 Gene3D G3DSA:1.10.10.10 1 86 2.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS10015 f29282b8340b1ceeff7c4c8bed6883de 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 64 4.9E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS10015 f29282b8340b1ceeff7c4c8bed6883de 302 Gene3D G3DSA:3.40.190.10 182 266 8.1E-16 T 28-03-2018 MKLM6_RS10015 f29282b8340b1ceeff7c4c8bed6883de 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 5.0E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS10015 f29282b8340b1ceeff7c4c8bed6883de 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 5.0E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS10015 f29282b8340b1ceeff7c4c8bed6883de 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 5.0E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS10015 f29282b8340b1ceeff7c4c8bed6883de 302 SUPERFAMILY SSF53850 91 296 2.76E-41 T 28-03-2018 MKLM6_RS11460 63f55b33af267eee8586aeed7cd7e4ef 916 SMART SM00052 660 907 4.1E-99 T 28-03-2018 IPR001633 EAL domain MKLM6_RS11460 63f55b33af267eee8586aeed7cd7e4ef 916 Pfam PF00563 EAL domain 667 902 5.2E-70 T 28-03-2018 IPR001633 EAL domain MKLM6_RS11460 63f55b33af267eee8586aeed7cd7e4ef 916 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 488 648 6.3E-45 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS11460 63f55b33af267eee8586aeed7cd7e4ef 916 Pfam PF13426 PAS domain 375 477 1.1E-14 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11460 63f55b33af267eee8586aeed7cd7e4ef 916 SMART SM00304 168 223 1.6E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS11460 63f55b33af267eee8586aeed7cd7e4ef 916 Pfam PF00990 Diguanylate cyclase, GGDEF domain 489 645 9.1E-53 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS11460 63f55b33af267eee8586aeed7cd7e4ef 916 SUPERFAMILY SSF55785 372 475 5.76E-26 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11460 63f55b33af267eee8586aeed7cd7e4ef 916 SUPERFAMILY SSF55073 494 652 6.59E-53 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS11460 63f55b33af267eee8586aeed7cd7e4ef 916 Pfam PF08447 PAS fold 272 341 6.0E-12 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS11460 63f55b33af267eee8586aeed7cd7e4ef 916 SMART SM00086 320 356 4.2 T 28-03-2018 IPR001610 PAC motif MKLM6_RS11460 63f55b33af267eee8586aeed7cd7e4ef 916 SMART SM00086 436 478 0.0045 T 28-03-2018 IPR001610 PAC motif MKLM6_RS11460 63f55b33af267eee8586aeed7cd7e4ef 916 SUPERFAMILY SSF55785 254 359 2.84E-22 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11460 63f55b33af267eee8586aeed7cd7e4ef 916 SMART SM00267 478 650 3.1E-69 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS11460 63f55b33af267eee8586aeed7cd7e4ef 916 SMART SM00091 364 430 3.8E-4 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11460 63f55b33af267eee8586aeed7cd7e4ef 916 SMART SM00091 248 314 2.7E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11460 63f55b33af267eee8586aeed7cd7e4ef 916 SUPERFAMILY SSF141868 666 913 5.89E-85 T 28-03-2018 IPR001633 EAL domain MKLM6_RS11460 63f55b33af267eee8586aeed7cd7e4ef 916 Gene3D G3DSA:3.30.450.20 359 475 4.9E-26 T 28-03-2018 MKLM6_RS11460 63f55b33af267eee8586aeed7cd7e4ef 916 Gene3D G3DSA:3.20.20.450 659 916 1.5E-95 T 28-03-2018 IPR001633 EAL domain MKLM6_RS11460 63f55b33af267eee8586aeed7cd7e4ef 916 Gene3D G3DSA:3.30.70.270 490 658 1.2E-63 T 28-03-2018 MKLM6_RS11460 63f55b33af267eee8586aeed7cd7e4ef 916 Gene3D G3DSA:3.30.450.20 214 358 8.9E-28 T 28-03-2018 MKLM6_RS11460 63f55b33af267eee8586aeed7cd7e4ef 916 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 246 363 2.4E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11460 63f55b33af267eee8586aeed7cd7e4ef 916 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 368 484 3.1E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS21570 226bcdfc1ffedcc3b568490dde7b7624 510 Gene3D G3DSA:1.10.287.130 267 337 9.7E-18 T 28-03-2018 MKLM6_RS21570 226bcdfc1ffedcc3b568490dde7b7624 510 Pfam PF00672 HAMP domain 203 250 4.1E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS21570 226bcdfc1ffedcc3b568490dde7b7624 510 SUPERFAMILY SSF47384 260 345 2.16E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS21570 226bcdfc1ffedcc3b568490dde7b7624 510 SMART SM00304 201 254 1.2E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS21570 226bcdfc1ffedcc3b568490dde7b7624 510 Pfam PF00512 His Kinase A (phospho-acceptor) domain 276 344 2.0E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS21570 226bcdfc1ffedcc3b568490dde7b7624 510 SUPERFAMILY SSF55874 334 498 2.49E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS21570 226bcdfc1ffedcc3b568490dde7b7624 510 SMART SM00387 390 501 1.8E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS21570 226bcdfc1ffedcc3b568490dde7b7624 510 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 391 498 8.3E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS21570 226bcdfc1ffedcc3b568490dde7b7624 510 Gene3D G3DSA:3.30.565.10 338 499 4.3E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS21570 226bcdfc1ffedcc3b568490dde7b7624 510 Gene3D G3DSA:3.30.450.20 41 177 6.3E-6 T 28-03-2018 MKLM6_RS21570 226bcdfc1ffedcc3b568490dde7b7624 510 SUPERFAMILY SSF158472 203 251 1.7E-8 T 28-03-2018 MKLM6_RS21570 226bcdfc1ffedcc3b568490dde7b7624 510 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 441 5.9E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS21570 226bcdfc1ffedcc3b568490dde7b7624 510 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 455 5.9E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS21570 226bcdfc1ffedcc3b568490dde7b7624 510 PRINTS PR00344 Bacterial sensor protein C-terminal signature 485 498 5.9E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS21570 226bcdfc1ffedcc3b568490dde7b7624 510 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 479 5.9E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS21570 226bcdfc1ffedcc3b568490dde7b7624 510 SMART SM00388 276 344 4.0E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS21570 226bcdfc1ffedcc3b568490dde7b7624 510 Pfam PF17152 Periplasmic sensor domain 47 163 5.9E-17 T 28-03-2018 IPR033417 Periplasmic sensor domain CHASE8 MKLM6_RS13560 14c316e747120a29c50226ee31c92fc1 131 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 98 1.0E-21 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 MKLM6_RS13560 14c316e747120a29c50226ee31c92fc1 131 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 115 2.4E-34 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 MKLM6_RS13560 14c316e747120a29c50226ee31c92fc1 131 SUPERFAMILY SSF89919 4 114 1.7E-31 T 28-03-2018 IPR023799 Ribosome-binding factor A domain MKLM6_RS13560 14c316e747120a29c50226ee31c92fc1 131 Gene3D G3DSA:3.30.300.20 1 104 6.8E-34 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta MKLM6_RS13560 14c316e747120a29c50226ee31c92fc1 131 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 3 118 20.704 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 MKLM6_RS13560 14c316e747120a29c50226ee31c92fc1 131 Pfam PF02033 Ribosome-binding factor A 7 111 2.6E-30 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 MKLM6_RS11075 a6dc60c0d1a387e983efebd3d0fd2010 464 Pfam PF07690 Major Facilitator Superfamily 50 394 6.0E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MKLM6_RS11075 a6dc60c0d1a387e983efebd3d0fd2010 464 Gene3D G3DSA:1.20.1250.20 15 221 3.9E-19 T 28-03-2018 MKLM6_RS11075 a6dc60c0d1a387e983efebd3d0fd2010 464 Gene3D G3DSA:1.20.1250.20 239 449 2.0E-21 T 28-03-2018 MKLM6_RS11075 a6dc60c0d1a387e983efebd3d0fd2010 464 SUPERFAMILY SSF103473 16 445 8.11E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain MKLM6_RS00630 edd0491d23352548c2c92b906d25d95d 176 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 176 2.9E-48 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00630 edd0491d23352548c2c92b906d25d95d 176 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 176 16.063 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00630 edd0491d23352548c2c92b906d25d95d 176 PRINTS PR00125 ATP synthase delta subunit signature 7 26 4.7E-22 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00630 edd0491d23352548c2c92b906d25d95d 176 PRINTS PR00125 ATP synthase delta subunit signature 86 100 4.7E-22 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00630 edd0491d23352548c2c92b906d25d95d 176 PRINTS PR00125 ATP synthase delta subunit signature 136 151 4.7E-22 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00630 edd0491d23352548c2c92b906d25d95d 176 PRINTS PR00125 ATP synthase delta subunit signature 75 86 4.7E-22 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00630 edd0491d23352548c2c92b906d25d95d 176 PRINTS PR00125 ATP synthase delta subunit signature 151 169 4.7E-22 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00630 edd0491d23352548c2c92b906d25d95d 176 SUPERFAMILY SSF47928 3 106 3.79E-22 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00630 edd0491d23352548c2c92b906d25d95d 176 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 8 176 3.7E-42 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00630 edd0491d23352548c2c92b906d25d95d 176 Gene3D G3DSA:1.10.520.20 2 107 8.7E-27 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS19145 1885a6b5b4eb45cf3edb8d3b52c8f684 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 2.1E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS19145 1885a6b5b4eb45cf3edb8d3b52c8f684 311 Gene3D G3DSA:1.10.10.10 2 91 6.6E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS19145 1885a6b5b4eb45cf3edb8d3b52c8f684 311 Pfam PF03466 LysR substrate binding domain 96 297 1.2E-20 T 28-03-2018 IPR005119 LysR, substrate-binding MKLM6_RS19145 1885a6b5b4eb45cf3edb8d3b52c8f684 311 SUPERFAMILY SSF53850 91 299 1.04E-41 T 28-03-2018 MKLM6_RS19145 1885a6b5b4eb45cf3edb8d3b52c8f684 311 SUPERFAMILY SSF46785 4 86 1.9E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS19145 1885a6b5b4eb45cf3edb8d3b52c8f684 311 Gene3D G3DSA:3.40.190.10 92 210 1.2E-22 T 28-03-2018 MKLM6_RS19145 1885a6b5b4eb45cf3edb8d3b52c8f684 311 Gene3D G3DSA:3.40.190.10 230 309 3.0E-5 T 28-03-2018 MKLM6_RS10855 1f2853f7f91c11b6f699abb62de4816a 364 SUPERFAMILY SSF51246 297 357 3.37E-12 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MKLM6_RS10855 1f2853f7f91c11b6f699abb62de4816a 364 Gene3D G3DSA:3.40.50.20 1 85 3.2E-22 T 28-03-2018 MKLM6_RS10855 1f2853f7f91c11b6f699abb62de4816a 364 Pfam PF02222 ATP-grasp domain 106 271 2.7E-52 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type MKLM6_RS10855 1f2853f7f91c11b6f699abb62de4816a 364 Gene3D G3DSA:3.30.470.20 175 359 7.5E-29 T 28-03-2018 MKLM6_RS10855 1f2853f7f91c11b6f699abb62de4816a 364 SUPERFAMILY SSF56059 97 292 1.56E-56 T 28-03-2018 MKLM6_RS10855 1f2853f7f91c11b6f699abb62de4816a 364 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 2 344 40.177 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 MKLM6_RS10855 1f2853f7f91c11b6f699abb62de4816a 364 Gene3D G3DSA:3.30.1490.20 112 174 2.4E-21 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MKLM6_RS10855 1f2853f7f91c11b6f699abb62de4816a 364 SUPERFAMILY SSF52440 2 94 8.78E-23 T 28-03-2018 IPR016185 Pre-ATP-grasp domain MKLM6_RS10855 1f2853f7f91c11b6f699abb62de4816a 364 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 2 345 2.3E-108 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 MKLM6_RS13085 0edf585db587ecd4c87ca4b1b855dc17 440 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 257 437 1.9E-24 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 MKLM6_RS13085 0edf585db587ecd4c87ca4b1b855dc17 440 Pfam PF01938 TRAM domain 12 62 5.2E-7 T 28-03-2018 IPR002792 TRAM domain MKLM6_RS13085 0edf585db587ecd4c87ca4b1b855dc17 440 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 423 433 - T 28-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site MKLM6_RS13085 0edf585db587ecd4c87ca4b1b855dc17 440 Gene3D G3DSA:2.40.50.140 1 77 1.1E-24 T 28-03-2018 MKLM6_RS13085 0edf585db587ecd4c87ca4b1b855dc17 440 Gene3D G3DSA:3.40.50.150 78 439 5.2E-55 T 28-03-2018 MKLM6_RS13085 0edf585db587ecd4c87ca4b1b855dc17 440 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 371 401 - T 28-03-2018 IPR030390 RNA methyltransferase TrmA, active site MKLM6_RS13085 0edf585db587ecd4c87ca4b1b855dc17 440 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 19 433 1.8E-102 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 MKLM6_RS13085 0edf585db587ecd4c87ca4b1b855dc17 440 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 13 440 64.925 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 MKLM6_RS13085 0edf585db587ecd4c87ca4b1b855dc17 440 SUPERFAMILY SSF53335 71 440 1.6E-84 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS13085 0edf585db587ecd4c87ca4b1b855dc17 440 SUPERFAMILY SSF50249 11 69 7.42E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS08930 a08656e276fb107752acbce835b2e250 716 Gene3D G3DSA:3.20.70.20 2 657 1.4E-148 T 28-03-2018 MKLM6_RS08930 a08656e276fb107752acbce835b2e250 716 PRINTS PR01183 Ribonucleotide reductase large chain signature 394 416 3.1E-17 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MKLM6_RS08930 a08656e276fb107752acbce835b2e250 716 PRINTS PR01183 Ribonucleotide reductase large chain signature 318 329 3.1E-17 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MKLM6_RS08930 a08656e276fb107752acbce835b2e250 716 PRINTS PR01183 Ribonucleotide reductase large chain signature 177 196 3.1E-17 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MKLM6_RS08930 a08656e276fb107752acbce835b2e250 716 PRINTS PR01183 Ribonucleotide reductase large chain signature 356 379 3.1E-17 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MKLM6_RS08930 a08656e276fb107752acbce835b2e250 716 PRINTS PR01183 Ribonucleotide reductase large chain signature 510 537 3.1E-17 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MKLM6_RS08930 a08656e276fb107752acbce835b2e250 716 PRINTS PR01183 Ribonucleotide reductase large chain signature 422 445 3.1E-17 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MKLM6_RS08930 a08656e276fb107752acbce835b2e250 716 SUPERFAMILY SSF51998 284 442 6.41E-169 T 28-03-2018 MKLM6_RS08930 a08656e276fb107752acbce835b2e250 716 SUPERFAMILY SSF51998 12 219 6.41E-169 T 28-03-2018 MKLM6_RS08930 a08656e276fb107752acbce835b2e250 716 SUPERFAMILY SSF51998 510 692 6.41E-169 T 28-03-2018 MKLM6_RS08930 a08656e276fb107752acbce835b2e250 716 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 20 91 1.3E-7 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MKLM6_RS08930 a08656e276fb107752acbce835b2e250 716 Pfam PF02867 Ribonucleotide reductase, barrel domain 102 652 4.7E-140 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MKLM6_RS08930 a08656e276fb107752acbce835b2e250 716 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 23 660 5.0E-170 T 28-03-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MKLM6_RS16965 b4198c69a92f0e38eca45fce83846bec 396 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 81 302 1.1E-13 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MKLM6_RS16965 b4198c69a92f0e38eca45fce83846bec 396 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 71 383 1.3E-71 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MKLM6_RS16965 b4198c69a92f0e38eca45fce83846bec 396 Gene3D G3DSA:2.40.50.100 79 151 1.2E-16 T 28-03-2018 MKLM6_RS16965 b4198c69a92f0e38eca45fce83846bec 396 Gene3D G3DSA:2.40.50.100 183 369 2.7E-7 T 28-03-2018 MKLM6_RS16965 b4198c69a92f0e38eca45fce83846bec 396 SUPERFAMILY SSF111369 72 306 2.75E-54 T 28-03-2018 MKLM6_RS13740 071e60a919ef9d94533a3a51fff2094b 235 Pfam PF02108 Flagellar assembly protein FliH 94 219 1.5E-35 T 28-03-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE MKLM6_RS13740 071e60a919ef9d94533a3a51fff2094b 235 PRINTS PR01003 Flagellar assembly protein FliH signature 116 133 1.3E-13 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 MKLM6_RS13740 071e60a919ef9d94533a3a51fff2094b 235 PRINTS PR01003 Flagellar assembly protein FliH signature 185 201 1.3E-13 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 MKLM6_RS13740 071e60a919ef9d94533a3a51fff2094b 235 PRINTS PR01003 Flagellar assembly protein FliH signature 157 184 1.3E-13 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 MKLM6_RS13740 071e60a919ef9d94533a3a51fff2094b 235 PRINTS PR01003 Flagellar assembly protein FliH signature 54 76 1.3E-13 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 MKLM6_RS13740 071e60a919ef9d94533a3a51fff2094b 235 PRINTS PR01003 Flagellar assembly protein FliH signature 202 227 1.3E-13 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 MKLM6_RS07150 c6c5ebd217a133b2b13be3d9f00c22b4 129 Gene3D G3DSA:3.30.1130.10 1 126 3.8E-29 T 28-03-2018 MKLM6_RS07150 c6c5ebd217a133b2b13be3d9f00c22b4 129 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 129 47.526 T 28-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MKLM6_RS07150 c6c5ebd217a133b2b13be3d9f00c22b4 129 Pfam PF14489 QueF-like protein 40 119 1.7E-31 T 28-03-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MKLM6_RS07150 c6c5ebd217a133b2b13be3d9f00c22b4 129 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 8 117 7.0E-49 T 28-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MKLM6_RS07150 c6c5ebd217a133b2b13be3d9f00c22b4 129 SUPERFAMILY SSF55620 4 112 1.63E-25 T 28-03-2018 MKLM6_RS07150 c6c5ebd217a133b2b13be3d9f00c22b4 129 PIRSF PIRSF027377 1 124 5.5E-52 T 28-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MKLM6_RS04500 3fa5ea376434f481749d39f166da6941 427 PRINTS PR00148 Enolase signature 311 322 1.5E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MKLM6_RS04500 3fa5ea376434f481749d39f166da6941 427 PRINTS PR00148 Enolase signature 37 51 1.5E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MKLM6_RS04500 3fa5ea376434f481749d39f166da6941 427 PRINTS PR00148 Enolase signature 363 380 1.5E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MKLM6_RS04500 3fa5ea376434f481749d39f166da6941 427 PRINTS PR00148 Enolase signature 107 123 1.5E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MKLM6_RS04500 3fa5ea376434f481749d39f166da6941 427 PRINTS PR00148 Enolase signature 334 348 1.5E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MKLM6_RS04500 3fa5ea376434f481749d39f166da6941 427 PRINTS PR00148 Enolase signature 161 174 1.5E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MKLM6_RS04500 3fa5ea376434f481749d39f166da6941 427 SUPERFAMILY SSF54826 4 136 2.92E-53 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MKLM6_RS04500 3fa5ea376434f481749d39f166da6941 427 ProSitePatterns PS00164 Enolase signature. 334 347 - T 28-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS04500 3fa5ea376434f481749d39f166da6941 427 SUPERFAMILY SSF51604 139 424 3.28E-131 T 28-03-2018 IPR029065 Enolase C-terminal domain-like MKLM6_RS04500 3fa5ea376434f481749d39f166da6941 427 Hamap MF_00318 Enolase [eno]. 2 411 44.593 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MKLM6_RS04500 3fa5ea376434f481749d39f166da6941 427 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 424 4.0E-136 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MKLM6_RS04500 3fa5ea376434f481749d39f166da6941 427 PIRSF PIRSF001400 1 425 3.9E-190 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MKLM6_RS04500 3fa5ea376434f481749d39f166da6941 427 Gene3D G3DSA:3.30.390.10 3 127 7.1E-50 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MKLM6_RS04500 3fa5ea376434f481749d39f166da6941 427 SMART SM01193 4 134 4.4E-87 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MKLM6_RS04500 3fa5ea376434f481749d39f166da6941 427 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 424 9.4E-209 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MKLM6_RS04500 3fa5ea376434f481749d39f166da6941 427 Gene3D G3DSA:3.20.20.120 129 427 8.1E-105 T 28-03-2018 IPR029065 Enolase C-terminal domain-like MKLM6_RS04500 3fa5ea376434f481749d39f166da6941 427 SMART SM01192 139 425 3.2E-221 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MKLM6_RS04500 3fa5ea376434f481749d39f166da6941 427 Pfam PF03952 Enolase, N-terminal domain 4 133 1.1E-56 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MKLM6_RS07850 236c87a558f7f790197226b8e48c2cbe 530 SMART SM00382 26 238 1.2E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS07850 236c87a558f7f790197226b8e48c2cbe 530 SMART SM00382 344 512 5.8E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS07850 236c87a558f7f790197226b8e48c2cbe 530 SUPERFAMILY SSF52540 297 526 3.33E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS07850 236c87a558f7f790197226b8e48c2cbe 530 Gene3D G3DSA:3.40.50.300 283 530 7.4E-47 T 28-03-2018 MKLM6_RS07850 236c87a558f7f790197226b8e48c2cbe 530 Gene3D G3DSA:3.40.50.300 2 282 3.6E-53 T 28-03-2018 MKLM6_RS07850 236c87a558f7f790197226b8e48c2cbe 530 Pfam PF00005 ABC transporter 336 467 7.7E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS07850 236c87a558f7f790197226b8e48c2cbe 530 Pfam PF00005 ABC transporter 18 184 9.0E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS07850 236c87a558f7f790197226b8e48c2cbe 530 SUPERFAMILY SSF52540 6 237 2.94E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS07850 236c87a558f7f790197226b8e48c2cbe 530 Pfam PF12848 ABC transporter 224 308 9.6E-22 T 28-03-2018 IPR032781 ABC-transporter extension domain MKLM6_RS01850 7101fcef2efa6df4d4d2353c2a14d555 1171 Gene3D G3DSA:3.90.320.10 895 1171 2.1E-64 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 MKLM6_RS01850 7101fcef2efa6df4d4d2353c2a14d555 1171 TIGRFAM TIGR00609 recB: exodeoxyribonuclease V, beta subunit 16 1167 6.3E-253 T 28-03-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 MKLM6_RS01850 7101fcef2efa6df4d4d2353c2a14d555 1171 SUPERFAMILY SSF52540 111 195 9.27E-103 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS01850 7101fcef2efa6df4d4d2353c2a14d555 1171 SUPERFAMILY SSF52540 326 765 9.27E-103 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS01850 7101fcef2efa6df4d4d2353c2a14d555 1171 SUPERFAMILY SSF52540 802 828 9.27E-103 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS01850 7101fcef2efa6df4d4d2353c2a14d555 1171 SUPERFAMILY SSF52540 12 71 9.27E-103 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS01850 7101fcef2efa6df4d4d2353c2a14d555 1171 Pfam PF00580 UvrD/REP helicase N-terminal domain 15 437 4.6E-56 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MKLM6_RS01850 7101fcef2efa6df4d4d2353c2a14d555 1171 Pfam PF13361 UvrD-like helicase C-terminal domain 522 825 1.1E-19 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MKLM6_RS01850 7101fcef2efa6df4d4d2353c2a14d555 1171 Pfam PF12705 PD-(D/E)XK nuclease superfamily 941 1141 2.9E-5 T 28-03-2018 MKLM6_RS01850 7101fcef2efa6df4d4d2353c2a14d555 1171 Gene3D G3DSA:3.40.50.300 2 446 7.3E-45 T 28-03-2018 MKLM6_RS01850 7101fcef2efa6df4d4d2353c2a14d555 1171 Hamap MF_01485 RecBCD enzyme subunit RecB [recB]. 4 1169 20.19 T 28-03-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 MKLM6_RS01850 7101fcef2efa6df4d4d2353c2a14d555 1171 SUPERFAMILY SSF52980 907 1168 3.27E-59 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MKLM6_RS01850 7101fcef2efa6df4d4d2353c2a14d555 1171 Gene3D G3DSA:3.40.50.300 520 841 9.0E-42 T 28-03-2018 MKLM6_RS00615 e297a981532a18ce75c4246b7851f499 254 Hamap MF_01393 ATP synthase subunit a [atpB]. 3 254 14.616 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00615 e297a981532a18ce75c4246b7851f499 254 Pfam PF00119 ATP synthase A chain 34 248 3.3E-51 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00615 e297a981532a18ce75c4246b7851f499 254 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 24 248 2.3E-39 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00615 e297a981532a18ce75c4246b7851f499 254 PRINTS PR00123 ATP synthase A subunit signature 167 182 4.6E-14 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00615 e297a981532a18ce75c4246b7851f499 254 PRINTS PR00123 ATP synthase A subunit signature 187 209 4.6E-14 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00615 e297a981532a18ce75c4246b7851f499 254 PRINTS PR00123 ATP synthase A subunit signature 90 106 4.6E-14 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00615 e297a981532a18ce75c4246b7851f499 254 PRINTS PR00123 ATP synthase A subunit signature 234 249 4.6E-14 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00615 e297a981532a18ce75c4246b7851f499 254 ProSitePatterns PS00449 ATP synthase a subunit signature. 190 199 - T 28-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00615 e297a981532a18ce75c4246b7851f499 254 Gene3D G3DSA:1.20.120.220 81 254 3.3E-44 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00615 e297a981532a18ce75c4246b7851f499 254 SUPERFAMILY SSF81336 83 248 2.09E-39 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS19895 101185ef5de2bbd83ab89e28eb77c533 285 Gene3D G3DSA:3.40.50.300 1 156 5.6E-10 T 28-03-2018 MKLM6_RS19895 101185ef5de2bbd83ab89e28eb77c533 285 SUPERFAMILY SSF52540 1 157 1.65E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS19895 101185ef5de2bbd83ab89e28eb77c533 285 PIRSF PIRSF005052 1 285 2.3E-111 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 MKLM6_RS19895 101185ef5de2bbd83ab89e28eb77c533 285 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 285 39.413 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 MKLM6_RS19895 101185ef5de2bbd83ab89e28eb77c533 285 Pfam PF03668 P-loop ATPase protein family 1 284 3.5E-97 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 MKLM6_RS14650 a89ef362cfe8d0c9f63770d5b8be2ccc 185 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 10 184 1.4E-62 T 28-03-2018 IPR027623 AmmeMemoRadiSam system protein A MKLM6_RS14650 a89ef362cfe8d0c9f63770d5b8be2ccc 185 Gene3D G3DSA:3.30.700.20 1 125 1.9E-35 T 28-03-2018 IPR027485 AMMECR1, N-terminal MKLM6_RS14650 a89ef362cfe8d0c9f63770d5b8be2ccc 185 Pfam PF01871 AMMECR1 13 183 2.2E-46 T 28-03-2018 IPR002733 AMMECR1 domain MKLM6_RS14650 a89ef362cfe8d0c9f63770d5b8be2ccc 185 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 3 184 4.7E-33 T 28-03-2018 IPR023473 AMMECR1 MKLM6_RS14650 a89ef362cfe8d0c9f63770d5b8be2ccc 185 SUPERFAMILY SSF143447 2 185 4.19E-55 T 28-03-2018 IPR002733 AMMECR1 domain MKLM6_RS14650 a89ef362cfe8d0c9f63770d5b8be2ccc 185 Gene3D G3DSA:3.30.1490.150 126 179 3.3E-16 T 28-03-2018 MKLM6_RS17445 24ccd9b52d01552a02f93cadc1c897c3 163 Pfam PF11684 Protein of unknown function (DUF2380) 22 154 3.9E-21 T 28-03-2018 IPR021698 Protein of unknown function DUF2380 MKLM6_RS17445 24ccd9b52d01552a02f93cadc1c897c3 163 Gene3D G3DSA:3.40.50.10070 13 162 1.9E-6 T 28-03-2018 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 Gene3D G3DSA:1.25.40.10 328 368 1.9E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 Gene3D G3DSA:1.25.40.10 369 472 1.1E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 Gene3D G3DSA:1.25.40.10 200 277 2.3E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 Gene3D G3DSA:1.25.40.10 473 537 2.6E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 SMART SM00028 148 181 0.0067 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 SMART SM00028 284 317 79.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 SMART SM00028 114 147 120.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 SMART SM00028 454 487 0.13 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 SMART SM00028 216 249 320.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 SMART SM00028 386 419 11.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 SMART SM00028 182 215 420.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 SMART SM00028 522 555 51.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 SMART SM00028 488 521 160.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 SMART SM00028 318 351 5.1E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 Pfam PF13432 Tetratricopeptide repeat 460 512 2.9E-4 T 28-03-2018 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 Gene3D G3DSA:1.25.40.10 278 327 3.9E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 Pfam PF13181 Tetratricopeptide repeat 319 351 1.2E-5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 SUPERFAMILY SSF48452 121 375 3.48E-32 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 Pfam PF07721 Tetratricopeptide repeat 356 375 0.38 T 28-03-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 Gene3D G3DSA:1.25.40.10 69 199 2.7E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 TIGRFAM TIGR02917 PEP_TPR_lipo: putative PEP-CTERM system TPR-repeat lipoprotein 84 582 3.0E-111 T 28-03-2018 IPR014266 PEP-CTERM system TPR-repeat lipoprotein, putative MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 Gene3D G3DSA:1.25.40.10 538 604 3.8E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 Pfam PF14559 Tetratricopeptide repeat 227 286 1.3E-5 T 28-03-2018 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 Pfam PF14559 Tetratricopeptide repeat 532 600 2.2E-7 T 28-03-2018 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 Pfam PF14559 Tetratricopeptide repeat 397 453 1.7E-5 T 28-03-2018 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 Pfam PF14559 Tetratricopeptide repeat 163 215 1.2E-6 T 28-03-2018 MKLM6_RS15220 648c3644fed2549079aa48d38b577917 604 SUPERFAMILY SSF48452 392 580 9.86E-26 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS14330 0432d82c1f457250409a747f1e7cd9ca 310 Pfam PF00174 Oxidoreductase molybdopterin binding domain 94 248 5.3E-29 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 MKLM6_RS14330 0432d82c1f457250409a747f1e7cd9ca 310 Gene3D G3DSA:3.90.420.10 51 273 5.0E-59 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 MKLM6_RS14330 0432d82c1f457250409a747f1e7cd9ca 310 Hamap MF_01206 Protein-methionine-sulfoxide reductase catalytic subunit MsrP [msrP]. 7 310 56.692 T 28-03-2018 IPR022867 Protein-methionine-sulfoxide reductase subunit MsrP GO:0016667|GO:0030091|GO:0043546|GO:0055114 MKLM6_RS14330 0432d82c1f457250409a747f1e7cd9ca 310 SUPERFAMILY SSF56524 62 306 2.22E-92 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 MKLM6_RS20275 6493bdf08c87bf2b08ad907018cb7edd 166 Gene3D G3DSA:3.10.450.40 13 158 2.3E-23 T 28-03-2018 MKLM6_RS20275 6493bdf08c87bf2b08ad907018cb7edd 166 SUPERFAMILY SSF160719 37 151 5.62E-9 T 28-03-2018 MKLM6_RS20275 6493bdf08c87bf2b08ad907018cb7edd 166 TIGRFAM TIGR03357 VI_zyme: type VI secretion system lysozyme-like protein 11 160 1.2E-25 T 28-03-2018 IPR017737 Type VI secretion system, lysozyme-related protein MKLM6_RS20275 6493bdf08c87bf2b08ad907018cb7edd 166 Pfam PF04965 Gene 25-like lysozyme 39 142 1.1E-24 T 28-03-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD MKLM6_RS05040 4b320db92fbe706e832d6e5a3016b747 157 SUPERFAMILY SSF48657 5 148 3.66E-34 T 28-03-2018 IPR016103 ProQ/FinO domain MKLM6_RS05040 4b320db92fbe706e832d6e5a3016b747 157 SMART SM00945 36 150 1.5E-34 T 28-03-2018 IPR016103 ProQ/FinO domain MKLM6_RS05040 4b320db92fbe706e832d6e5a3016b747 157 Pfam PF04352 ProQ/FINO family 39 144 2.6E-32 T 28-03-2018 IPR016103 ProQ/FinO domain MKLM6_RS05040 4b320db92fbe706e832d6e5a3016b747 157 Gene3D G3DSA:1.10.1710.10 4 152 8.6E-39 T 28-03-2018 IPR016103 ProQ/FinO domain MKLM6_RS20390 4eb59f14a26c191b9e41beb2f2eec8f7 415 SUPERFAMILY SSF50621 253 413 2.72E-55 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MKLM6_RS20390 4eb59f14a26c191b9e41beb2f2eec8f7 415 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 15 412 41.602 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MKLM6_RS20390 4eb59f14a26c191b9e41beb2f2eec8f7 415 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 225 241 - T 28-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site MKLM6_RS20390 4eb59f14a26c191b9e41beb2f2eec8f7 415 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 7 411 3.6E-158 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MKLM6_RS20390 4eb59f14a26c191b9e41beb2f2eec8f7 415 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 29 369 4.7E-24 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 MKLM6_RS20390 4eb59f14a26c191b9e41beb2f2eec8f7 415 PRINTS PR01181 Diaminopimelate decarboxylase signature 164 173 5.4E-30 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MKLM6_RS20390 4eb59f14a26c191b9e41beb2f2eec8f7 415 PRINTS PR01181 Diaminopimelate decarboxylase signature 298 316 5.4E-30 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MKLM6_RS20390 4eb59f14a26c191b9e41beb2f2eec8f7 415 PRINTS PR01181 Diaminopimelate decarboxylase signature 379 401 5.4E-30 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MKLM6_RS20390 4eb59f14a26c191b9e41beb2f2eec8f7 415 PRINTS PR01181 Diaminopimelate decarboxylase signature 75 92 5.4E-30 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MKLM6_RS20390 4eb59f14a26c191b9e41beb2f2eec8f7 415 Gene3D G3DSA:2.40.37.10 267 415 5.7E-48 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MKLM6_RS20390 4eb59f14a26c191b9e41beb2f2eec8f7 415 SUPERFAMILY SSF51419 26 282 2.22E-80 T 28-03-2018 IPR029066 PLP-binding barrel MKLM6_RS20390 4eb59f14a26c191b9e41beb2f2eec8f7 415 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 369 382 5.6E-27 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MKLM6_RS20390 4eb59f14a26c191b9e41beb2f2eec8f7 415 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 77 89 5.6E-27 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MKLM6_RS20390 4eb59f14a26c191b9e41beb2f2eec8f7 415 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 190 203 5.6E-27 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MKLM6_RS20390 4eb59f14a26c191b9e41beb2f2eec8f7 415 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 270 289 5.6E-27 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MKLM6_RS20390 4eb59f14a26c191b9e41beb2f2eec8f7 415 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 57 75 5.6E-27 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MKLM6_RS20390 4eb59f14a26c191b9e41beb2f2eec8f7 415 Gene3D G3DSA:3.20.20.10 34 266 3.9E-61 T 28-03-2018 IPR029066 PLP-binding barrel MKLM6_RS20390 4eb59f14a26c191b9e41beb2f2eec8f7 415 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 57 75 - T 28-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site MKLM6_RS20390 4eb59f14a26c191b9e41beb2f2eec8f7 415 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 35 280 7.3E-70 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 MKLM6_RS19620 889405ec83081c9a20973b8a2a2779b4 301 Pfam PF00990 Diguanylate cyclase, GGDEF domain 138 298 1.4E-49 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS19620 889405ec83081c9a20973b8a2a2779b4 301 SUPERFAMILY SSF52172 5 132 2.85E-39 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS19620 889405ec83081c9a20973b8a2a2779b4 301 SMART SM00267 127 301 2.2E-61 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS19620 889405ec83081c9a20973b8a2a2779b4 301 SMART SM00448 8 121 2.0E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS19620 889405ec83081c9a20973b8a2a2779b4 301 Pfam PF00072 Response regulator receiver domain 10 121 3.7E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS19620 889405ec83081c9a20973b8a2a2779b4 301 Gene3D G3DSA:3.30.70.270 135 301 6.0E-52 T 28-03-2018 MKLM6_RS19620 889405ec83081c9a20973b8a2a2779b4 301 SUPERFAMILY SSF55073 143 300 2.2E-46 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS19620 889405ec83081c9a20973b8a2a2779b4 301 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 134 299 4.7E-52 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS19620 889405ec83081c9a20973b8a2a2779b4 301 Gene3D G3DSA:3.40.50.2300 2 134 9.9E-36 T 28-03-2018 MKLM6_RS13860 7ea58b0ab1df168baea3967be3eb0065 199 PIRSF PIRSF006806 1 190 8.2E-39 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase MKLM6_RS13860 7ea58b0ab1df168baea3967be3eb0065 199 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 3 187 1.3E-38 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase MKLM6_RS13860 7ea58b0ab1df168baea3967be3eb0065 199 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 3 187 3.4E-39 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase MKLM6_RS13860 7ea58b0ab1df168baea3967be3eb0065 199 SUPERFAMILY SSF100950 1 192 9.63E-43 T 28-03-2018 MKLM6_RS13860 7ea58b0ab1df168baea3967be3eb0065 199 Gene3D G3DSA:3.40.50.10420 1 191 6.0E-49 T 28-03-2018 MKLM6_RS12500 73bee5d35f33f1f9a6abc26d1dab2f35 519 TIGRFAM TIGR00561 pntA: NAD(P)(+) transhydrogenase (AB-specific), alpha subunit 2 519 5.2E-247 T 28-03-2018 IPR026255 NAD(P) transhydrogenase, alpha subunit GO:0008746|GO:0015992|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 MKLM6_RS12500 73bee5d35f33f1f9a6abc26d1dab2f35 519 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 145 1.6E-47 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MKLM6_RS12500 73bee5d35f33f1f9a6abc26d1dab2f35 519 SMART SM01003 4 145 4.9E-69 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MKLM6_RS12500 73bee5d35f33f1f9a6abc26d1dab2f35 519 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 149 375 5.0E-77 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MKLM6_RS12500 73bee5d35f33f1f9a6abc26d1dab2f35 519 Gene3D G3DSA:3.40.50.720 204 384 7.0E-57 T 28-03-2018 MKLM6_RS12500 73bee5d35f33f1f9a6abc26d1dab2f35 519 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 178 203 - T 28-03-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 Reactome: R-HSA-71403 MKLM6_RS12500 73bee5d35f33f1f9a6abc26d1dab2f35 519 SUPERFAMILY SSF52283 1 176 5.95E-54 T 28-03-2018 MKLM6_RS12500 73bee5d35f33f1f9a6abc26d1dab2f35 519 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 436 519 1.5E-34 T 28-03-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 MKLM6_RS12500 73bee5d35f33f1f9a6abc26d1dab2f35 519 SUPERFAMILY SSF51735 145 324 2.7E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS12500 73bee5d35f33f1f9a6abc26d1dab2f35 519 SMART SM01002 154 318 4.1E-88 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MKLM6_RS12500 73bee5d35f33f1f9a6abc26d1dab2f35 519 Gene3D G3DSA:3.40.50.720 1 203 1.7E-48 T 28-03-2018 MKLM6_RS12500 73bee5d35f33f1f9a6abc26d1dab2f35 519 PIRSF PIRSF000203 1 519 1.4E-265 T 28-03-2018 IPR026255 NAD(P) transhydrogenase, alpha subunit GO:0008746|GO:0015992|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 MKLM6_RS22020 143c6936934a52953cc3488da2aaf47f 157 Pfam PF04002 RadC-like JAB domain 37 155 2.2E-44 T 28-03-2018 IPR025657 RadC-like JAB domain MKLM6_RS22020 143c6936934a52953cc3488da2aaf47f 157 Gene3D G3DSA:3.40.140.10 33 157 3.5E-45 T 28-03-2018 MKLM6_RS22020 143c6936934a52953cc3488da2aaf47f 157 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 107 112 - T 28-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site MKLM6_RS22020 143c6936934a52953cc3488da2aaf47f 157 SUPERFAMILY SSF102712 70 128 4.18E-5 T 28-03-2018 MKLM6_RS22020 143c6936934a52953cc3488da2aaf47f 157 TIGRFAM TIGR00608 radc: DNA repair protein RadC 31 157 1.4E-41 T 28-03-2018 IPR001405 RadC protein MKLM6_RS08890 27d9013f095123f67f833ed3c4dde9c6 225 Gene3D G3DSA:1.10.10.10 119 225 2.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS08890 27d9013f095123f67f833ed3c4dde9c6 225 SMART SM00862 145 218 4.1E-14 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS08890 27d9013f095123f67f833ed3c4dde9c6 225 Pfam PF00072 Response regulator receiver domain 3 112 1.3E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS08890 27d9013f095123f67f833ed3c4dde9c6 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 218 7.7E-16 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS08890 27d9013f095123f67f833ed3c4dde9c6 225 SMART SM00448 1 112 4.9E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS08890 27d9013f095123f67f833ed3c4dde9c6 225 SUPERFAMILY SSF52172 1 166 1.31E-36 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS08890 27d9013f095123f67f833ed3c4dde9c6 225 Gene3D G3DSA:3.40.50.2300 1 118 1.5E-34 T 28-03-2018 MKLM6_RS03385 7255c3e6967b376cf23593e10d4949cb 338 Gene3D G3DSA:3.40.1570.10 191 334 3.6E-20 T 28-03-2018 MKLM6_RS03385 7255c3e6967b376cf23593e10d4949cb 338 SUPERFAMILY SSF144064 17 332 1.28E-76 T 28-03-2018 MKLM6_RS03385 7255c3e6967b376cf23593e10d4949cb 338 Pfam PF05171 Haemin-degrading HemS.ChuX domain 218 330 1.2E-16 T 28-03-2018 IPR007845 Haemin-degrading HemS/ChuX domain GO:0006826 MKLM6_RS03385 7255c3e6967b376cf23593e10d4949cb 338 Pfam PF05171 Haemin-degrading HemS.ChuX domain 41 168 6.8E-38 T 28-03-2018 IPR007845 Haemin-degrading HemS/ChuX domain GO:0006826 MKLM6_RS03385 7255c3e6967b376cf23593e10d4949cb 338 Gene3D G3DSA:3.40.1570.10 17 186 2.2E-51 T 28-03-2018 MKLM6_RS18540 cfdf9cb07f650dc33bef3cb670730267 198 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 5 97 21.196 T 28-03-2018 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 MKLM6_RS18540 cfdf9cb07f650dc33bef3cb670730267 198 Pfam PF01386 Ribosomal L25p family 9 94 8.6E-24 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 MKLM6_RS18540 cfdf9cb07f650dc33bef3cb670730267 198 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 5 190 28.939 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 MKLM6_RS18540 cfdf9cb07f650dc33bef3cb670730267 198 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 9 172 7.4E-46 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 MKLM6_RS18540 cfdf9cb07f650dc33bef3cb670730267 198 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 7 97 4.0E-23 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 MKLM6_RS18540 cfdf9cb07f650dc33bef3cb670730267 198 Gene3D G3DSA:2.40.240.10 4 97 2.5E-28 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MKLM6_RS18540 cfdf9cb07f650dc33bef3cb670730267 198 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 103 191 2.5E-28 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain MKLM6_RS18540 cfdf9cb07f650dc33bef3cb670730267 198 Gene3D G3DSA:2.170.120.20 101 196 7.1E-30 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain MKLM6_RS18540 cfdf9cb07f650dc33bef3cb670730267 198 SUPERFAMILY SSF50715 5 197 4.53E-55 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MKLM6_RS13910 2a6289a0cd8a38f2ad92d7780ead22e2 775 Gene3D G3DSA:3.40.710.10 360 757 3.5E-99 T 28-03-2018 MKLM6_RS13910 2a6289a0cd8a38f2ad92d7780ead22e2 775 TIGRFAM TIGR02071 PBP_1b: penicillin-binding protein 1B 29 753 3.0E-262 T 28-03-2018 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MKLM6_RS13910 2a6289a0cd8a38f2ad92d7780ead22e2 775 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 172 710 1.6E-155 T 28-03-2018 MKLM6_RS13910 2a6289a0cd8a38f2ad92d7780ead22e2 775 Pfam PF14814 Bifunctional transglycosylase second domain 72 156 7.2E-21 T 28-03-2018 IPR028166 Bifunctional transglycosylase second domain KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MKLM6_RS13910 2a6289a0cd8a38f2ad92d7780ead22e2 775 Gene3D G3DSA:3.30.2060.10 71 155 1.7E-21 T 28-03-2018 MKLM6_RS13910 2a6289a0cd8a38f2ad92d7780ead22e2 775 Gene3D G3DSA:1.10.3810.10 156 356 4.9E-67 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 MKLM6_RS13910 2a6289a0cd8a38f2ad92d7780ead22e2 775 SUPERFAMILY SSF53955 152 362 1.1E-67 T 28-03-2018 IPR023346 Lysozyme-like domain MKLM6_RS13910 2a6289a0cd8a38f2ad92d7780ead22e2 775 Pfam PF00912 Transglycosylase 167 339 1.7E-58 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 MKLM6_RS13910 2a6289a0cd8a38f2ad92d7780ead22e2 775 Gene3D G3DSA:1.20.5.100 13 54 5.4E-6 T 28-03-2018 MKLM6_RS13910 2a6289a0cd8a38f2ad92d7780ead22e2 775 Pfam PF00905 Penicillin binding protein transpeptidase domain 433 672 6.9E-16 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MKLM6_RS13910 2a6289a0cd8a38f2ad92d7780ead22e2 775 PIRSF PIRSF002799 1 774 5.8E-303 T 28-03-2018 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MKLM6_RS13910 2a6289a0cd8a38f2ad92d7780ead22e2 775 SUPERFAMILY SSF56601 321 343 1.6E-113 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MKLM6_RS13910 2a6289a0cd8a38f2ad92d7780ead22e2 775 SUPERFAMILY SSF56601 372 759 1.6E-113 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MKLM6_RS13695 26a596098023adba544052580768c2e1 797 Gene3D G3DSA:3.20.20.60 484 794 1.1E-99 T 28-03-2018 MKLM6_RS13695 26a596098023adba544052580768c2e1 797 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 697 715 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 MKLM6_RS13695 26a596098023adba544052580768c2e1 797 SUPERFAMILY SSF52009 355 468 8.5E-32 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MKLM6_RS13695 26a596098023adba544052580768c2e1 797 Gene3D G3DSA:3.30.1490.20 3 196 5.5E-55 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MKLM6_RS13695 26a596098023adba544052580768c2e1 797 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 20 345 9.4E-118 T 28-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 MKLM6_RS13695 26a596098023adba544052580768c2e1 797 Gene3D G3DSA:3.30.470.20 197 359 2.4E-43 T 28-03-2018 MKLM6_RS13695 26a596098023adba544052580768c2e1 797 SUPERFAMILY SSF51621 463 794 2.2E-93 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MKLM6_RS13695 26a596098023adba544052580768c2e1 797 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 7 793 0.0 T 28-03-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 MKLM6_RS13695 26a596098023adba544052580768c2e1 797 Gene3D G3DSA:3.50.30.10 360 483 1.8E-35 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MKLM6_RS13695 26a596098023adba544052580768c2e1 797 PIRSF PIRSF000854 2 797 0.0 T 28-03-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 MKLM6_RS13695 26a596098023adba544052580768c2e1 797 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 416 427 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 MKLM6_RS13695 26a596098023adba544052580768c2e1 797 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 482 789 1.0E-57 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 MKLM6_RS13695 26a596098023adba544052580768c2e1 797 Pfam PF00391 PEP-utilising enzyme, mobile domain 386 457 6.0E-25 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MKLM6_RS13695 26a596098023adba544052580768c2e1 797 SUPERFAMILY SSF56059 5 386 4.36E-108 T 28-03-2018 MKLM6_RS15790 15c96c38fec4fe3a9fd124f8aaa4b25f 358 SUPERFAMILY SSF51735 2 334 3.74E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS15790 15c96c38fec4fe3a9fd124f8aaa4b25f 358 Pfam PF16363 GDP-mannose 4,6 dehydratase 12 321 7.3E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS15790 15c96c38fec4fe3a9fd124f8aaa4b25f 358 Gene3D G3DSA:3.90.25.10 196 350 1.2E-25 T 28-03-2018 MKLM6_RS15790 15c96c38fec4fe3a9fd124f8aaa4b25f 358 Gene3D G3DSA:3.40.50.720 1 195 7.2E-34 T 28-03-2018 MKLM6_RS15790 15c96c38fec4fe3a9fd124f8aaa4b25f 358 TIGRFAM TIGR02622 CDP_4_6_dhtase: CDP-glucose 4,6-dehydratase 5 346 9.3E-147 T 28-03-2018 IPR013445 CDP-glucose 4,6-dehydratase KEGG: 00520+4.2.1.45|MetaCyc: PWY-5833 MKLM6_RS10095 0bc491a952e7236aa541c3a7e8d93c60 164 Pfam PF07963 Prokaryotic N-terminal methylation motif 22 45 3.9E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS10095 0bc491a952e7236aa541c3a7e8d93c60 164 TIGRFAM TIGR02523 type_IV_pilV: type IV pilus modification protein PilV 24 148 3.1E-24 T 28-03-2018 IPR013362 Pilus modification type IV, PilV MKLM6_RS10095 0bc491a952e7236aa541c3a7e8d93c60 164 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 28 45 2.3E-4 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS14545 36782a68281cd382e35e200b361fc690 704 Pfam PF04607 Region found in RelA / SpoT proteins 235 345 2.7E-37 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 MKLM6_RS14545 36782a68281cd382e35e200b361fc690 704 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 46 702 2.4E-182 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 MKLM6_RS14545 36782a68281cd382e35e200b361fc690 704 SUPERFAMILY SSF109604 44 190 2.73E-38 T 28-03-2018 MKLM6_RS14545 36782a68281cd382e35e200b361fc690 704 SUPERFAMILY SSF81301 180 388 5.72E-63 T 28-03-2018 MKLM6_RS14545 36782a68281cd382e35e200b361fc690 704 SMART SM00954 235 345 2.2E-64 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 MKLM6_RS14545 36782a68281cd382e35e200b361fc690 704 SUPERFAMILY SSF55021 626 702 7.08E-10 T 28-03-2018 MKLM6_RS14545 36782a68281cd382e35e200b361fc690 704 Pfam PF02824 TGS domain 384 443 1.2E-20 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 MKLM6_RS14545 36782a68281cd382e35e200b361fc690 704 Pfam PF13328 HD domain 45 175 3.0E-33 T 28-03-2018 IPR003607 HD/PDEase domain MKLM6_RS14545 36782a68281cd382e35e200b361fc690 704 Gene3D G3DSA:3.30.70.260 620 703 4.3E-9 T 28-03-2018 MKLM6_RS14545 36782a68281cd382e35e200b361fc690 704 Gene3D G3DSA:3.30.460.10 192 325 1.9E-43 T 28-03-2018 MKLM6_RS14545 36782a68281cd382e35e200b361fc690 704 Pfam PF13291 ACT domain 628 702 2.1E-16 T 28-03-2018 IPR002912 ACT domain MKLM6_RS14545 36782a68281cd382e35e200b361fc690 704 Gene3D G3DSA:3.10.20.30 378 453 7.6E-22 T 28-03-2018 IPR012675 Beta-grasp domain MKLM6_RS14545 36782a68281cd382e35e200b361fc690 704 SUPERFAMILY SSF81271 374 443 4.8E-20 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MKLM6_RS20465 fbd9e6b7aef4670e87638498ff2eaef1 145 Gene3D G3DSA:3.40.250.10 26 145 3.4E-29 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS20465 fbd9e6b7aef4670e87638498ff2eaef1 145 SMART SM00450 40 137 1.4E-25 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS20465 fbd9e6b7aef4670e87638498ff2eaef1 145 SUPERFAMILY SSF52821 16 138 2.88E-32 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS20465 fbd9e6b7aef4670e87638498ff2eaef1 145 Pfam PF00581 Rhodanese-like domain 46 132 3.8E-18 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS15645 24a9951e5de3712c1b8ac1fc5b9ec8dd 790 Gene3D G3DSA:3.10.20.310 281 360 4.6E-13 T 28-03-2018 MKLM6_RS15645 24a9951e5de3712c1b8ac1fc5b9ec8dd 790 Gene3D G3DSA:3.10.20.310 34 105 1.2E-8 T 28-03-2018 MKLM6_RS15645 24a9951e5de3712c1b8ac1fc5b9ec8dd 790 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 15 790 24.135 T 28-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 MKLM6_RS15645 24a9951e5de3712c1b8ac1fc5b9ec8dd 790 Gene3D G3DSA:3.10.20.310 189 280 8.5E-20 T 28-03-2018 MKLM6_RS15645 24a9951e5de3712c1b8ac1fc5b9ec8dd 790 Pfam PF01103 Surface antigen 462 790 1.6E-59 T 28-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 MKLM6_RS15645 24a9951e5de3712c1b8ac1fc5b9ec8dd 790 Gene3D G3DSA:2.40.160.50 393 790 4.0E-70 T 28-03-2018 MKLM6_RS15645 24a9951e5de3712c1b8ac1fc5b9ec8dd 790 Pfam PF07244 Surface antigen variable number repeat 107 186 1.8E-11 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 MKLM6_RS15645 24a9951e5de3712c1b8ac1fc5b9ec8dd 790 Pfam PF07244 Surface antigen variable number repeat 282 358 1.1E-11 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 MKLM6_RS15645 24a9951e5de3712c1b8ac1fc5b9ec8dd 790 Pfam PF07244 Surface antigen variable number repeat 39 104 5.8E-5 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 MKLM6_RS15645 24a9951e5de3712c1b8ac1fc5b9ec8dd 790 Pfam PF07244 Surface antigen variable number repeat 361 435 1.4E-12 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 MKLM6_RS15645 24a9951e5de3712c1b8ac1fc5b9ec8dd 790 Pfam PF07244 Surface antigen variable number repeat 190 277 1.8E-18 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 MKLM6_RS15645 24a9951e5de3712c1b8ac1fc5b9ec8dd 790 Gene3D G3DSA:3.10.20.310 106 188 8.6E-14 T 28-03-2018 MKLM6_RS15645 24a9951e5de3712c1b8ac1fc5b9ec8dd 790 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 38 790 1.5E-250 T 28-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 MKLM6_RS15645 24a9951e5de3712c1b8ac1fc5b9ec8dd 790 PIRSF PIRSF006076 1 790 1.3E-243 T 28-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 MKLM6_RS00535 57eae5852a3023375d6d89e468f8f121 623 SUPERFAMILY SSF55073 188 351 2.75E-45 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS00535 57eae5852a3023375d6d89e468f8f121 623 SUPERFAMILY SSF141868 365 612 1.96E-86 T 28-03-2018 IPR001633 EAL domain MKLM6_RS00535 57eae5852a3023375d6d89e468f8f121 623 SMART SM00267 172 349 2.8E-45 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS00535 57eae5852a3023375d6d89e468f8f121 623 SMART SM00052 359 605 1.3E-111 T 28-03-2018 IPR001633 EAL domain MKLM6_RS00535 57eae5852a3023375d6d89e468f8f121 623 Gene3D G3DSA:3.20.20.450 357 618 4.1E-98 T 28-03-2018 IPR001633 EAL domain MKLM6_RS00535 57eae5852a3023375d6d89e468f8f121 623 Gene3D G3DSA:3.30.70.270 177 356 3.7E-55 T 28-03-2018 MKLM6_RS00535 57eae5852a3023375d6d89e468f8f121 623 Pfam PF00990 Diguanylate cyclase, GGDEF domain 183 345 1.8E-43 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS00535 57eae5852a3023375d6d89e468f8f121 623 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 180 348 2.4E-39 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS00535 57eae5852a3023375d6d89e468f8f121 623 Pfam PF00563 EAL domain 365 600 1.1E-71 T 28-03-2018 IPR001633 EAL domain MKLM6_RS21460 760b2807cde5dc05e2507a36b7c65221 544 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 271 286 9.6E-21 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS21460 760b2807cde5dc05e2507a36b7c65221 544 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 242 255 9.6E-21 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS21460 760b2807cde5dc05e2507a36b7c65221 544 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 206 225 9.6E-21 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS21460 760b2807cde5dc05e2507a36b7c65221 544 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 106 120 9.6E-21 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS21460 760b2807cde5dc05e2507a36b7c65221 544 Gene3D G3DSA:3.40.120.10 301 402 2.6E-38 T 28-03-2018 MKLM6_RS21460 760b2807cde5dc05e2507a36b7c65221 544 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 467 515 7.1E-6 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS21460 760b2807cde5dc05e2507a36b7c65221 544 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 14 152 8.7E-36 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS21460 760b2807cde5dc05e2507a36b7c65221 544 SUPERFAMILY SSF53738 183 292 2.0E-27 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS21460 760b2807cde5dc05e2507a36b7c65221 544 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 184 287 6.6E-9 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS21460 760b2807cde5dc05e2507a36b7c65221 544 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 296 408 2.7E-30 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS21460 760b2807cde5dc05e2507a36b7c65221 544 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 107 116 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS21460 760b2807cde5dc05e2507a36b7c65221 544 Gene3D G3DSA:3.30.310.50 403 544 2.4E-63 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS21460 760b2807cde5dc05e2507a36b7c65221 544 SUPERFAMILY SSF53738 279 415 9.42E-36 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS21460 760b2807cde5dc05e2507a36b7c65221 544 SUPERFAMILY SSF55957 410 544 8.89E-47 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS21460 760b2807cde5dc05e2507a36b7c65221 544 Gene3D G3DSA:3.40.120.10 2 187 7.8E-39 T 28-03-2018 MKLM6_RS21460 760b2807cde5dc05e2507a36b7c65221 544 Gene3D G3DSA:3.40.120.10 188 300 7.5E-25 T 28-03-2018 MKLM6_RS21460 760b2807cde5dc05e2507a36b7c65221 544 SUPERFAMILY SSF53738 3 198 4.32E-47 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MKLM6_RS15295 39d1eb6149bbaf672b8b7d0ad461f563 758 Pfam PF00575 S1 RNA binding domain 648 717 9.4E-22 T 28-03-2018 IPR003029 S1 domain GO:0003676 MKLM6_RS15295 39d1eb6149bbaf672b8b7d0ad461f563 758 Gene3D G3DSA:1.10.10.650 1 100 1.4E-33 T 28-03-2018 IPR023319 Tex-like protein, HTH domain MKLM6_RS15295 39d1eb6149bbaf672b8b7d0ad461f563 758 SUPERFAMILY SSF47781 557 629 7.78E-20 T 28-03-2018 IPR010994 RuvA domain 2-like MKLM6_RS15295 39d1eb6149bbaf672b8b7d0ad461f563 758 SUPERFAMILY SSF53098 318 466 8.34E-53 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS15295 39d1eb6149bbaf672b8b7d0ad461f563 758 Pfam PF12836 Helix-hairpin-helix motif 488 552 2.1E-27 T 28-03-2018 MKLM6_RS15295 39d1eb6149bbaf672b8b7d0ad461f563 758 SMART SM00316 646 717 6.1E-26 T 28-03-2018 IPR022967 RNA-binding domain, S1 MKLM6_RS15295 39d1eb6149bbaf672b8b7d0ad461f563 758 SUPERFAMILY SSF158832 1 317 3.4E-116 T 28-03-2018 MKLM6_RS15295 39d1eb6149bbaf672b8b7d0ad461f563 758 Pfam PF16921 Tex protein YqgF-like domain 322 448 2.2E-54 T 28-03-2018 IPR032639 Tex protein, YqgF-like domain MKLM6_RS15295 39d1eb6149bbaf672b8b7d0ad461f563 758 Gene3D G3DSA:2.40.50.140 650 749 1.2E-26 T 28-03-2018 MKLM6_RS15295 39d1eb6149bbaf672b8b7d0ad461f563 758 SMART SM00732 322 421 3.7E-40 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 MKLM6_RS15295 39d1eb6149bbaf672b8b7d0ad461f563 758 Gene3D G3DSA:1.10.3500.10 101 351 6.9E-77 T 28-03-2018 IPR023323 Tex-like domain MKLM6_RS15295 39d1eb6149bbaf672b8b7d0ad461f563 758 SUPERFAMILY SSF47781 467 554 4.45E-27 T 28-03-2018 IPR010994 RuvA domain 2-like MKLM6_RS15295 39d1eb6149bbaf672b8b7d0ad461f563 758 SUPERFAMILY SSF50249 635 734 4.72E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS15295 39d1eb6149bbaf672b8b7d0ad461f563 758 Gene3D G3DSA:1.10.150.310 496 627 1.6E-41 T 28-03-2018 MKLM6_RS15295 39d1eb6149bbaf672b8b7d0ad461f563 758 Gene3D G3DSA:1.10.3500.10 352 495 4.4E-43 T 28-03-2018 IPR023323 Tex-like domain MKLM6_RS15295 39d1eb6149bbaf672b8b7d0ad461f563 758 Pfam PF09371 Tex-like protein N-terminal domain 7 190 2.4E-71 T 28-03-2018 IPR018974 Tex-like protein, N-terminal MKLM6_RS11315 a55b9e3ee37b479f88616234d228170d 413 SUPERFAMILY SSF53187 20 214 1.29E-86 T 28-03-2018 MKLM6_RS11315 a55b9e3ee37b479f88616234d228170d 413 SUPERFAMILY SSF53187 315 410 1.29E-86 T 28-03-2018 MKLM6_RS11315 a55b9e3ee37b479f88616234d228170d 413 Gene3D G3DSA:3.40.630.10 2 258 1.1E-50 T 28-03-2018 MKLM6_RS11315 a55b9e3ee37b479f88616234d228170d 413 Gene3D G3DSA:3.40.630.10 264 413 5.5E-23 T 28-03-2018 MKLM6_RS11315 a55b9e3ee37b479f88616234d228170d 413 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 33 398 9.5E-104 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 MKLM6_RS11315 a55b9e3ee37b479f88616234d228170d 413 PIRSF PIRSF005962 18 412 2.3E-123 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 MKLM6_RS11315 a55b9e3ee37b479f88616234d228170d 413 Pfam PF01546 Peptidase family M20/M25/M40 90 371 5.6E-33 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 MKLM6_RS11315 a55b9e3ee37b479f88616234d228170d 413 Pfam PF07687 Peptidase dimerisation domain 202 297 1.3E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain MKLM6_RS11315 a55b9e3ee37b479f88616234d228170d 413 SUPERFAMILY SSF55031 201 313 2.75E-29 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain MKLM6_RS13660 afc013b66a2976fc14506c1d04509f8a 217 Pfam PF12710 haloacid dehalogenase-like hydrolase 4 187 1.0E-38 T 28-03-2018 MKLM6_RS13660 afc013b66a2976fc14506c1d04509f8a 217 Gene3D G3DSA:1.20.1440.100 16 79 9.7E-29 T 28-03-2018 MKLM6_RS13660 afc013b66a2976fc14506c1d04509f8a 217 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 3 190 1.2E-26 T 28-03-2018 MKLM6_RS13660 afc013b66a2976fc14506c1d04509f8a 217 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 3 201 2.9E-45 T 28-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like MKLM6_RS13660 afc013b66a2976fc14506c1d04509f8a 217 Gene3D G3DSA:3.40.50.1000 80 209 1.1E-13 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS13660 afc013b66a2976fc14506c1d04509f8a 217 SUPERFAMILY SSF56784 3 209 6.64E-35 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS21170 268471813890ddbf35fb71380971eb11 494 Gene3D G3DSA:3.60.120.10 13 485 3.9E-169 T 28-03-2018 IPR005801 ADC synthase GO:0009058 MKLM6_RS21170 268471813890ddbf35fb71380971eb11 494 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 26 483 1.8E-173 T 28-03-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MKLM6_RS21170 268471813890ddbf35fb71380971eb11 494 Pfam PF04715 Anthranilate synthase component I, N terminal region 26 168 6.9E-32 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MKLM6_RS21170 268471813890ddbf35fb71380971eb11 494 SUPERFAMILY SSF56322 14 484 1.05E-158 T 28-03-2018 IPR005801 ADC synthase GO:0009058 MKLM6_RS21170 268471813890ddbf35fb71380971eb11 494 Pfam PF00425 chorismate binding enzyme 222 475 2.1E-98 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal MKLM6_RS21170 268471813890ddbf35fb71380971eb11 494 PRINTS PR00095 Anthranilate synthase component I signature 337 350 2.6E-24 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MKLM6_RS21170 268471813890ddbf35fb71380971eb11 494 PRINTS PR00095 Anthranilate synthase component I signature 432 446 2.6E-24 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MKLM6_RS21170 268471813890ddbf35fb71380971eb11 494 PRINTS PR00095 Anthranilate synthase component I signature 323 336 2.6E-24 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MKLM6_RS21170 268471813890ddbf35fb71380971eb11 494 PRINTS PR00095 Anthranilate synthase component I signature 417 431 2.6E-24 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MKLM6_RS12565 617b3e71dfe238fbf9cc9d54ee4ce6c9 311 Pfam PF00586 AIR synthase related protein, N-terminal domain 29 138 5.2E-24 T 28-03-2018 IPR016188 PurM-like, N-terminal domain MKLM6_RS12565 617b3e71dfe238fbf9cc9d54ee4ce6c9 311 Pfam PF02769 AIR synthase related protein, C-terminal domain 150 249 2.3E-8 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MKLM6_RS12565 617b3e71dfe238fbf9cc9d54ee4ce6c9 311 SUPERFAMILY SSF55326 4 138 1.26E-34 T 28-03-2018 IPR016188 PurM-like, N-terminal domain MKLM6_RS12565 617b3e71dfe238fbf9cc9d54ee4ce6c9 311 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 4 310 2.2E-96 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 MKLM6_RS12565 617b3e71dfe238fbf9cc9d54ee4ce6c9 311 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 3 307 30.017 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 MKLM6_RS12565 617b3e71dfe238fbf9cc9d54ee4ce6c9 311 Gene3D G3DSA:3.90.650.10 145 310 1.1E-38 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MKLM6_RS12565 617b3e71dfe238fbf9cc9d54ee4ce6c9 311 SUPERFAMILY SSF56042 143 295 4.19E-37 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MKLM6_RS12565 617b3e71dfe238fbf9cc9d54ee4ce6c9 311 Gene3D G3DSA:3.30.1330.10 1 144 1.8E-36 T 28-03-2018 IPR016188 PurM-like, N-terminal domain MKLM6_RS12565 617b3e71dfe238fbf9cc9d54ee4ce6c9 311 PIRSF PIRSF005303 1 310 3.0E-82 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 MKLM6_RS10585 9ff16e1986e94484f4209e24ac24a953 280 Pfam PF08668 HDOD domain 24 201 1.9E-41 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD MKLM6_RS10585 9ff16e1986e94484f4209e24ac24a953 280 SUPERFAMILY SSF109604 15 253 2.43E-51 T 28-03-2018 MKLM6_RS10585 9ff16e1986e94484f4209e24ac24a953 280 Gene3D G3DSA:1.10.3210.10 2 228 6.9E-40 T 28-03-2018 MKLM6_RS17285 c253137accf9240785800087ce6133d3 262 SMART SM00563 90 198 6.1E-15 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MKLM6_RS17285 c253137accf9240785800087ce6133d3 262 Pfam PF01553 Acyltransferase 83 194 3.8E-12 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MKLM6_RS17285 c253137accf9240785800087ce6133d3 262 Gene3D G3DSA:3.40.1130.10 46 262 1.5E-22 T 28-03-2018 MKLM6_RS17285 c253137accf9240785800087ce6133d3 262 SUPERFAMILY SSF69593 55 252 7.32E-25 T 28-03-2018 MKLM6_RS20450 b553d8632160e63f7981fd6ef1f06706 454 Pfam PF03572 Peptidase family S41 206 371 1.9E-56 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 MKLM6_RS20450 b553d8632160e63f7981fd6ef1f06706 454 SUPERFAMILY SSF50156 98 191 2.75E-20 T 28-03-2018 IPR001478 PDZ domain GO:0005515 MKLM6_RS20450 b553d8632160e63f7981fd6ef1f06706 454 Gene3D G3DSA:3.30.750.44 40 115 3.0E-16 T 28-03-2018 MKLM6_RS20450 b553d8632160e63f7981fd6ef1f06706 454 SMART SM00245 181 373 2.8E-72 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 MKLM6_RS20450 b553d8632160e63f7981fd6ef1f06706 454 Pfam PF13180 PDZ domain 108 185 6.4E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 MKLM6_RS20450 b553d8632160e63f7981fd6ef1f06706 454 Gene3D G3DSA:2.30.42.10 116 181 2.7E-17 T 28-03-2018 MKLM6_RS20450 b553d8632160e63f7981fd6ef1f06706 454 Gene3D G3DSA:3.90.226.10 182 448 5.0E-70 T 28-03-2018 MKLM6_RS20450 b553d8632160e63f7981fd6ef1f06706 454 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 60 378 3.1E-104 T 28-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 MKLM6_RS20450 b553d8632160e63f7981fd6ef1f06706 454 SUPERFAMILY SSF52096 200 373 1.33E-83 T 28-03-2018 IPR029045 ClpP/crotonase-like domain MKLM6_RS20450 b553d8632160e63f7981fd6ef1f06706 454 SUPERFAMILY SSF52096 45 126 1.33E-83 T 28-03-2018 IPR029045 ClpP/crotonase-like domain MKLM6_RS20450 b553d8632160e63f7981fd6ef1f06706 454 SMART SM00228 108 179 2.1E-16 T 28-03-2018 IPR001478 PDZ domain GO:0005515 MKLM6_RS08815 50e4e77ee5156ef0073672661fd05092 247 SUPERFAMILY SSF53067 1 117 3.82E-21 T 28-03-2018 MKLM6_RS08815 50e4e77ee5156ef0073672661fd05092 247 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 244 20.34 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MKLM6_RS08815 50e4e77ee5156ef0073672661fd05092 247 Pfam PF03309 Type III pantothenate kinase 2 199 1.5E-46 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MKLM6_RS08815 50e4e77ee5156ef0073672661fd05092 247 Gene3D G3DSA:3.30.420.40 84 244 2.5E-48 T 28-03-2018 MKLM6_RS08815 50e4e77ee5156ef0073672661fd05092 247 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 3 237 5.0E-31 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MKLM6_RS08815 50e4e77ee5156ef0073672661fd05092 247 SUPERFAMILY SSF53067 120 239 1.64E-27 T 28-03-2018 MKLM6_RS05845 a374c9d396b3c5c173df2980e47ac627 289 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 118 278 5.1E-63 T 28-03-2018 IPR005273 Uracil-DNA glycosylase family 4 MKLM6_RS05845 a374c9d396b3c5c173df2980e47ac627 289 SUPERFAMILY SSF52141 108 285 2.43E-60 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MKLM6_RS05845 a374c9d396b3c5c173df2980e47ac627 289 SMART SM00987 132 278 1.7E-40 T 28-03-2018 MKLM6_RS05845 a374c9d396b3c5c173df2980e47ac627 289 SMART SM00986 132 278 1.7E-40 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MKLM6_RS05845 a374c9d396b3c5c173df2980e47ac627 289 Gene3D G3DSA:3.40.470.10 91 288 5.6E-61 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MKLM6_RS05845 a374c9d396b3c5c173df2980e47ac627 289 Pfam PF03167 Uracil DNA glycosylase superfamily 132 278 9.2E-45 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MKLM6_RS17500 2059c62f526df9818af29ae7fcf911ac 237 Gene3D G3DSA:3.30.460.10 36 231 7.5E-45 T 28-03-2018 MKLM6_RS17500 2059c62f526df9818af29ae7fcf911ac 237 SUPERFAMILY SSF81301 42 229 9.81E-39 T 28-03-2018 MKLM6_RS17500 2059c62f526df9818af29ae7fcf911ac 237 Pfam PF04229 GrpB protein 41 222 1.9E-39 T 28-03-2018 IPR007344 GrpB/Dephospho-CoA kinase MKLM6_RS00290 20bb40e3fb292a43e5c11c41c1d284ff 416 SUPERFAMILY SSF116734 13 188 3.92E-25 T 28-03-2018 MKLM6_RS00290 20bb40e3fb292a43e5c11c41c1d284ff 416 Gene3D G3DSA:3.90.220.20 9 127 4.3E-11 T 28-03-2018 MKLM6_RS00290 20bb40e3fb292a43e5c11c41c1d284ff 416 Gene3D G3DSA:1.10.287.1120 128 172 1.6E-5 T 28-03-2018 MKLM6_RS00290 20bb40e3fb292a43e5c11c41c1d284ff 416 SUPERFAMILY SSF116734 197 409 2.78E-33 T 28-03-2018 MKLM6_RS00290 20bb40e3fb292a43e5c11c41c1d284ff 416 Pfam PF01420 Type I restriction modification DNA specificity domain 211 379 2.1E-5 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MKLM6_RS00290 20bb40e3fb292a43e5c11c41c1d284ff 416 Pfam PF01420 Type I restriction modification DNA specificity domain 17 170 5.5E-8 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MKLM6_RS00290 20bb40e3fb292a43e5c11c41c1d284ff 416 Gene3D G3DSA:3.90.220.20 173 383 3.9E-28 T 28-03-2018 MKLM6_RS05665 d107c8f413cee00f55890ac185ddc699 356 SMART SM00448 49 164 1.2E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS05665 d107c8f413cee00f55890ac185ddc699 356 SUPERFAMILY SSF55874 266 328 6.52E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS05665 d107c8f413cee00f55890ac185ddc699 356 SUPERFAMILY SSF55874 206 238 6.52E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS05665 d107c8f413cee00f55890ac185ddc699 356 Gene3D G3DSA:3.40.50.2300 39 174 2.9E-34 T 28-03-2018 MKLM6_RS05665 d107c8f413cee00f55890ac185ddc699 356 Gene3D G3DSA:3.30.565.10 175 327 2.4E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS05665 d107c8f413cee00f55890ac185ddc699 356 SUPERFAMILY SSF52172 48 182 6.69E-37 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS05665 d107c8f413cee00f55890ac185ddc699 356 Pfam PF00072 Response regulator receiver domain 51 164 4.7E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS05665 d107c8f413cee00f55890ac185ddc699 356 Pfam PF13581 Histidine kinase-like ATPase domain 223 337 2.1E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS16865 a665b52fa2ddae3ea78dbdbc1d5c0e9b 431 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 364 380 1.9E-27 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MKLM6_RS16865 a665b52fa2ddae3ea78dbdbc1d5c0e9b 431 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 314 326 1.9E-27 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MKLM6_RS16865 a665b52fa2ddae3ea78dbdbc1d5c0e9b 431 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 218 232 1.9E-27 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MKLM6_RS16865 a665b52fa2ddae3ea78dbdbc1d5c0e9b 431 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 412 429 1.9E-27 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MKLM6_RS16865 a665b52fa2ddae3ea78dbdbc1d5c0e9b 431 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 247 257 1.9E-27 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MKLM6_RS16865 a665b52fa2ddae3ea78dbdbc1d5c0e9b 431 Gene3D G3DSA:3.30.70.1170 169 226 4.1E-17 T 28-03-2018 MKLM6_RS16865 a665b52fa2ddae3ea78dbdbc1d5c0e9b 431 SUPERFAMILY SSF53335 141 429 4.76E-66 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS16865 a665b52fa2ddae3ea78dbdbc1d5c0e9b 431 Gene3D G3DSA:1.10.287.730 142 167 1.3E-7 T 28-03-2018 MKLM6_RS16865 a665b52fa2ddae3ea78dbdbc1d5c0e9b 431 Gene3D G3DSA:3.40.50.150 227 431 4.5E-52 T 28-03-2018 MKLM6_RS16865 a665b52fa2ddae3ea78dbdbc1d5c0e9b 431 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 4 429 2.6E-123 T 28-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MKLM6_RS16865 a665b52fa2ddae3ea78dbdbc1d5c0e9b 431 Pfam PF01189 16S rRNA methyltransferase RsmB/F 237 428 8.8E-60 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MKLM6_RS16865 a665b52fa2ddae3ea78dbdbc1d5c0e9b 431 Gene3D G3DSA:1.10.940.10 1 141 5.8E-30 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MKLM6_RS16865 a665b52fa2ddae3ea78dbdbc1d5c0e9b 431 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 313 324 - T 28-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MKLM6_RS16865 a665b52fa2ddae3ea78dbdbc1d5c0e9b 431 SUPERFAMILY SSF48013 1 145 1.39E-32 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MKLM6_RS16865 a665b52fa2ddae3ea78dbdbc1d5c0e9b 431 Pfam PF01029 NusB family 2 122 3.1E-22 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MKLM6_RS16905 c0c73ebe62fea05b81be1da4d13a38cf 163 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 4.0E-35 T 28-03-2018 MKLM6_RS16905 c0c73ebe62fea05b81be1da4d13a38cf 163 SUPERFAMILY SSF55021 79 161 3.97E-26 T 28-03-2018 MKLM6_RS16905 c0c73ebe62fea05b81be1da4d13a38cf 163 Pfam PF10369 Small subunit of acetolactate synthase 84 157 2.6E-27 T 28-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MKLM6_RS16905 c0c73ebe62fea05b81be1da4d13a38cf 163 Gene3D G3DSA:3.30.70.260 1 87 3.1E-24 T 28-03-2018 MKLM6_RS16905 c0c73ebe62fea05b81be1da4d13a38cf 163 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 158 6.0E-66 T 28-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MKLM6_RS16905 c0c73ebe62fea05b81be1da4d13a38cf 163 SUPERFAMILY SSF55021 1 74 4.31E-23 T 28-03-2018 MKLM6_RS16905 c0c73ebe62fea05b81be1da4d13a38cf 163 Gene3D G3DSA:3.30.70.1150 88 160 2.6E-28 T 28-03-2018 MKLM6_RS16905 c0c73ebe62fea05b81be1da4d13a38cf 163 Pfam PF13710 ACT domain 12 72 1.1E-16 T 28-03-2018 MKLM6_RS08120 c257373c51de68a73b8976c1ea1ea09a 230 SUPERFAMILY SSF56436 35 208 2.5E-26 T 28-03-2018 IPR016187 C-type lectin fold MKLM6_RS08120 c257373c51de68a73b8976c1ea1ea09a 230 Gene3D G3DSA:3.10.100.10 30 229 6.6E-35 T 28-03-2018 IPR016186 C-type lectin-like/link domain MKLM6_RS12195 cd9be0fbde2ac40af4f7368e93d7a8bb 177 Pfam PF13689 Domain of unknown function (DUF4154) 40 174 2.9E-35 T 28-03-2018 IPR025293 Protein of unknown function DUF4154 MKLM6_RS02500 8dc2a54dbe49cdbebd83fca55b84eacc 358 Gene3D G3DSA:1.10.530.10 147 332 6.6E-22 T 28-03-2018 MKLM6_RS02500 8dc2a54dbe49cdbebd83fca55b84eacc 358 SUPERFAMILY SSF90123 36 116 9.03E-5 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MKLM6_RS02500 8dc2a54dbe49cdbebd83fca55b84eacc 358 Pfam PF01464 Transglycosylase SLT domain 189 289 2.4E-11 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 MKLM6_RS02500 8dc2a54dbe49cdbebd83fca55b84eacc 358 SUPERFAMILY SSF53955 185 332 1.27E-18 T 28-03-2018 IPR023346 Lysozyme-like domain MKLM6_RS18055 7f6113cd6a96a2f27595e07bb567b05a 391 Gene3D G3DSA:3.40.50.2000 210 346 1.5E-22 T 28-03-2018 MKLM6_RS18055 7f6113cd6a96a2f27595e07bb567b05a 391 TIGRFAM TIGR03568 NeuC_NnaA: UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing 5 371 9.0E-145 T 28-03-2018 IPR020004 UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing GO:0004553|GO:0006047 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-4085001 MKLM6_RS18055 7f6113cd6a96a2f27595e07bb567b05a 391 Gene3D G3DSA:3.40.50.2000 5 209 2.0E-50 T 28-03-2018 MKLM6_RS18055 7f6113cd6a96a2f27595e07bb567b05a 391 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 25 371 1.2E-93 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 MKLM6_RS18055 7f6113cd6a96a2f27595e07bb567b05a 391 SUPERFAMILY SSF53756 5 385 4.02E-98 T 28-03-2018 MKLM6_RS16610 8fa6bd47226f2393a751a9b72e1ee9e7 136 TIGRFAM TIGR02096 TIGR02096: conserved hypothetical protein 6 132 7.3E-43 T 28-03-2018 IPR011721 Conserved hypothetical protein CHP02096 MKLM6_RS16610 8fa6bd47226f2393a751a9b72e1ee9e7 136 Gene3D G3DSA:3.10.450.50 1 133 3.3E-25 T 28-03-2018 MKLM6_RS16610 8fa6bd47226f2393a751a9b72e1ee9e7 136 SUPERFAMILY SSF54427 1 128 9.85E-32 T 28-03-2018 IPR032710 NTF2-like domain MKLM6_RS16610 8fa6bd47226f2393a751a9b72e1ee9e7 136 Pfam PF12680 SnoaL-like domain 9 118 5.4E-19 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MKLM6_RS09925 9e55c8500192b640341e3c31f15218dd 390 Gene3D G3DSA:1.20.1600.10 1 388 1.5E-33 T 28-03-2018 MKLM6_RS09925 9e55c8500192b640341e3c31f15218dd 390 Pfam PF02321 Outer membrane efflux protein 203 374 6.7E-17 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS09925 9e55c8500192b640341e3c31f15218dd 390 Pfam PF02321 Outer membrane efflux protein 2 179 9.6E-5 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS09925 9e55c8500192b640341e3c31f15218dd 390 SUPERFAMILY SSF56954 2 383 1.1E-46 T 28-03-2018 MKLM6_RS02790 d2f49ebef7507b0717cc7e847c09bddd 294 Pfam PF00691 OmpA family 146 244 7.2E-20 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS02790 d2f49ebef7507b0717cc7e847c09bddd 294 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 4 59 1.3E-21 T 28-03-2018 IPR025713 Motility protein B, N-terminal domain MKLM6_RS02790 d2f49ebef7507b0717cc7e847c09bddd 294 Gene3D G3DSA:3.30.1330.60 45 279 6.0E-41 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS02790 d2f49ebef7507b0717cc7e847c09bddd 294 SUPERFAMILY SSF103088 139 250 3.66E-33 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS09145 8088ece8cd9314d07ea22c31cb29a51d 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 8.4E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MKLM6_RS09145 8088ece8cd9314d07ea22c31cb29a51d 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 8.4E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MKLM6_RS09145 8088ece8cd9314d07ea22c31cb29a51d 219 SUPERFAMILY SSF46689 5 73 4.57E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS09145 8088ece8cd9314d07ea22c31cb29a51d 219 Pfam PF09209 Domain of unknown function (DUF1956) 85 205 3.4E-20 T 28-03-2018 IPR015292 Transcription regulator YbiH, C-terminal MKLM6_RS09145 8088ece8cd9314d07ea22c31cb29a51d 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 1.6E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MKLM6_RS09145 8088ece8cd9314d07ea22c31cb29a51d 219 SUPERFAMILY SSF48498 82 208 4.6E-13 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MKLM6_RS09145 8088ece8cd9314d07ea22c31cb29a51d 219 Gene3D G3DSA:1.10.357.10 51 214 1.1E-30 T 28-03-2018 MKLM6_RS09145 8088ece8cd9314d07ea22c31cb29a51d 219 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 57 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MKLM6_RS09145 8088ece8cd9314d07ea22c31cb29a51d 219 Gene3D G3DSA:1.10.10.60 3 50 2.3E-15 T 28-03-2018 MKLM6_RS03975 261a7c9bca35c5ab9834971653d98fe7 726 SMART SM00642 253 598 6.4E-7 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MKLM6_RS03975 261a7c9bca35c5ab9834971653d98fe7 726 PIRSF PIRSF000463 11 726 2.9E-299 T 28-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 MKLM6_RS03975 261a7c9bca35c5ab9834971653d98fe7 726 SUPERFAMILY SSF51011 627 725 5.85E-31 T 28-03-2018 MKLM6_RS03975 261a7c9bca35c5ab9834971653d98fe7 726 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 125 209 4.7E-23 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 MKLM6_RS03975 261a7c9bca35c5ab9834971653d98fe7 726 Gene3D G3DSA:3.20.20.80 238 638 1.5E-81 T 28-03-2018 MKLM6_RS03975 261a7c9bca35c5ab9834971653d98fe7 726 Pfam PF00128 Alpha amylase, catalytic domain 278 350 1.5E-11 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MKLM6_RS03975 261a7c9bca35c5ab9834971653d98fe7 726 Gene3D G3DSA:2.60.40.10 106 225 2.5E-31 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS03975 261a7c9bca35c5ab9834971653d98fe7 726 Gene3D G3DSA:2.60.40.10 6 105 2.5E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS03975 261a7c9bca35c5ab9834971653d98fe7 726 SUPERFAMILY SSF81296 21 116 1.85E-12 T 28-03-2018 IPR014756 Immunoglobulin E-set MKLM6_RS03975 261a7c9bca35c5ab9834971653d98fe7 726 SUPERFAMILY SSF51445 181 620 1.87E-121 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily MKLM6_RS03975 261a7c9bca35c5ab9834971653d98fe7 726 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 110 725 4.0E-283 T 28-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 MKLM6_RS03975 261a7c9bca35c5ab9834971653d98fe7 726 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 102 726 45.107 T 28-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 MKLM6_RS03975 261a7c9bca35c5ab9834971653d98fe7 726 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 631 725 1.6E-20 T 28-03-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 MKLM6_RS03975 261a7c9bca35c5ab9834971653d98fe7 726 SUPERFAMILY SSF81296 139 193 5.18E-11 T 28-03-2018 IPR014756 Immunoglobulin E-set MKLM6_RS03975 261a7c9bca35c5ab9834971653d98fe7 726 Gene3D G3DSA:2.60.40.1180 639 726 5.3E-33 T 28-03-2018 MKLM6_RS22210 20d52e6bbbf6ecb6cc58e89d98b94176 105 Pfam PF00816 H-NS histone family 11 98 9.6E-23 T 28-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 MKLM6_RS22210 20d52e6bbbf6ecb6cc58e89d98b94176 105 SMART SM00528 60 105 5.2E-14 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 MKLM6_RS22210 20d52e6bbbf6ecb6cc58e89d98b94176 105 SUPERFAMILY SSF81273 64 105 3.57E-12 T 28-03-2018 MKLM6_RS22210 20d52e6bbbf6ecb6cc58e89d98b94176 105 Gene3D G3DSA:4.10.430.10 66 105 7.3E-18 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 MKLM6_RS14805 c385096ac6cdddd85e9416a24a4dbcd9 645 PRINTS PR00301 70kDa heat shock protein signature 334 350 9.2E-82 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MKLM6_RS14805 c385096ac6cdddd85e9416a24a4dbcd9 645 PRINTS PR00301 70kDa heat shock protein signature 469 485 9.2E-82 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MKLM6_RS14805 c385096ac6cdddd85e9416a24a4dbcd9 645 PRINTS PR00301 70kDa heat shock protein signature 54 62 9.2E-82 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MKLM6_RS14805 c385096ac6cdddd85e9416a24a4dbcd9 645 PRINTS PR00301 70kDa heat shock protein signature 138 158 9.2E-82 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MKLM6_RS14805 c385096ac6cdddd85e9416a24a4dbcd9 645 PRINTS PR00301 70kDa heat shock protein signature 198 208 9.2E-82 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MKLM6_RS14805 c385096ac6cdddd85e9416a24a4dbcd9 645 PRINTS PR00301 70kDa heat shock protein signature 365 385 9.2E-82 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MKLM6_RS14805 c385096ac6cdddd85e9416a24a4dbcd9 645 PRINTS PR00301 70kDa heat shock protein signature 388 407 9.2E-82 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MKLM6_RS14805 c385096ac6cdddd85e9416a24a4dbcd9 645 PRINTS PR00301 70kDa heat shock protein signature 3 16 9.2E-82 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MKLM6_RS14805 c385096ac6cdddd85e9416a24a4dbcd9 645 PRINTS PR00301 70kDa heat shock protein signature 31 43 9.2E-82 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MKLM6_RS14805 c385096ac6cdddd85e9416a24a4dbcd9 645 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 337 351 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MKLM6_RS14805 c385096ac6cdddd85e9416a24a4dbcd9 645 SUPERFAMILY SSF53067 187 382 3.62E-67 T 28-03-2018 MKLM6_RS14805 c385096ac6cdddd85e9416a24a4dbcd9 645 SUPERFAMILY SSF100920 384 540 4.32E-62 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 MKLM6_RS14805 c385096ac6cdddd85e9416a24a4dbcd9 645 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 603 7.7E-290 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 MKLM6_RS14805 c385096ac6cdddd85e9416a24a4dbcd9 645 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MKLM6_RS14805 c385096ac6cdddd85e9416a24a4dbcd9 645 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 640 36.866 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 MKLM6_RS14805 c385096ac6cdddd85e9416a24a4dbcd9 645 SUPERFAMILY SSF53067 4 184 4.26E-64 T 28-03-2018 MKLM6_RS14805 c385096ac6cdddd85e9416a24a4dbcd9 645 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 192 205 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MKLM6_RS14805 c385096ac6cdddd85e9416a24a4dbcd9 645 Gene3D G3DSA:3.30.420.40 1 196 9.0E-80 T 28-03-2018 MKLM6_RS14805 c385096ac6cdddd85e9416a24a4dbcd9 645 Gene3D G3DSA:1.20.1270.10 532 618 2.1E-22 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain MKLM6_RS14805 c385096ac6cdddd85e9416a24a4dbcd9 645 Gene3D G3DSA:3.30.420.40 197 366 2.9E-44 T 28-03-2018 MKLM6_RS14805 c385096ac6cdddd85e9416a24a4dbcd9 645 Pfam PF00012 Hsp70 protein 4 603 5.3E-262 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MKLM6_RS14805 c385096ac6cdddd85e9416a24a4dbcd9 645 Gene3D G3DSA:2.60.34.10 390 531 4.0E-64 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 MKLM6_RS14805 c385096ac6cdddd85e9416a24a4dbcd9 645 SUPERFAMILY SSF100934 507 605 1.22E-22 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain MKLM6_RS16560 4c3e8fc666aa610490f47f7bddfc8680 271 SUPERFAMILY SSF46946 132 224 7.95E-28 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MKLM6_RS16560 4c3e8fc666aa610490f47f7bddfc8680 271 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 115 1.8E-34 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MKLM6_RS16560 4c3e8fc666aa610490f47f7bddfc8680 271 SMART SM00898 2 116 4.0E-54 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MKLM6_RS16560 4c3e8fc666aa610490f47f7bddfc8680 271 SUPERFAMILY SSF81624 2 136 1.23E-42 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MKLM6_RS16560 4c3e8fc666aa610490f47f7bddfc8680 271 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 271 43.058 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 MKLM6_RS16560 4c3e8fc666aa610490f47f7bddfc8680 271 ProSitePatterns PS01242 Zinc finger FPG-type signature. 246 270 - T 28-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 MKLM6_RS16560 4c3e8fc666aa610490f47f7bddfc8680 271 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 270 1.1E-93 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 MKLM6_RS16560 4c3e8fc666aa610490f47f7bddfc8680 271 Gene3D G3DSA:3.20.190.10 1 132 7.5E-42 T 28-03-2018 MKLM6_RS16560 4c3e8fc666aa610490f47f7bddfc8680 271 SMART SM01232 131 223 5.6E-46 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MKLM6_RS16560 4c3e8fc666aa610490f47f7bddfc8680 271 Gene3D G3DSA:1.10.8.50 133 271 1.2E-45 T 28-03-2018 MKLM6_RS16560 4c3e8fc666aa610490f47f7bddfc8680 271 SUPERFAMILY SSF57716 219 270 2.77E-15 T 28-03-2018 MKLM6_RS16560 4c3e8fc666aa610490f47f7bddfc8680 271 Pfam PF06827 Zinc finger found in FPG and IleRS 243 270 3.4E-7 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 MKLM6_RS16560 4c3e8fc666aa610490f47f7bddfc8680 271 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 131 220 1.2E-23 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MKLM6_RS04185 d87c597f3369c0e9f1709b6b084bebf9 220 Pfam PF10552 ORF6C domain 84 145 6.6E-5 T 28-03-2018 IPR018878 ORF6C domain MKLM6_RS15685 d0d5d59f6025bf3a9c2d3eb998afdfe0 994 Gene3D G3DSA:3.30.1330.60 567 977 7.4E-12 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS15685 d0d5d59f6025bf3a9c2d3eb998afdfe0 994 Pfam PF05359 Domain of Unknown Function (DUF748) 371 522 5.7E-37 T 28-03-2018 IPR008023 Protein of unknown function DUF748 MKLM6_RS15685 d0d5d59f6025bf3a9c2d3eb998afdfe0 994 Pfam PF05359 Domain of Unknown Function (DUF748) 595 738 9.4E-33 T 28-03-2018 IPR008023 Protein of unknown function DUF748 MKLM6_RS15685 d0d5d59f6025bf3a9c2d3eb998afdfe0 994 Pfam PF05359 Domain of Unknown Function (DUF748) 151 303 5.8E-20 T 28-03-2018 IPR008023 Protein of unknown function DUF748 MKLM6_RS10565 ce434600a10c3f77f497ac43cc0632d6 110 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 3 107 1.0E-33 T 28-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 MKLM6_RS10565 ce434600a10c3f77f497ac43cc0632d6 110 SUPERFAMILY SSF50022 1 109 1.43E-37 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MKLM6_RS10565 ce434600a10c3f77f497ac43cc0632d6 110 Pfam PF13806 Rieske-like [2Fe-2S] domain 3 107 4.0E-39 T 28-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 MKLM6_RS10565 ce434600a10c3f77f497ac43cc0632d6 110 Gene3D G3DSA:2.102.10.10 1 110 1.5E-19 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MKLM6_RS00900 e89a67a8dabc5a79847c90b38cb42722 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 9.4E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS00900 e89a67a8dabc5a79847c90b38cb42722 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 9.4E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS00900 e89a67a8dabc5a79847c90b38cb42722 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 9.4E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS00900 e89a67a8dabc5a79847c90b38cb42722 210 SUPERFAMILY SSF52172 1 131 1.37E-33 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS00900 e89a67a8dabc5a79847c90b38cb42722 210 Gene3D G3DSA:1.10.10.10 124 209 3.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS00900 e89a67a8dabc5a79847c90b38cb42722 210 SUPERFAMILY SSF46894 137 203 4.76E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MKLM6_RS00900 e89a67a8dabc5a79847c90b38cb42722 210 Pfam PF00072 Response regulator receiver domain 5 116 4.3E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS00900 e89a67a8dabc5a79847c90b38cb42722 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 202 3.5E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS00900 e89a67a8dabc5a79847c90b38cb42722 210 Gene3D G3DSA:3.40.50.2300 1 123 5.0E-34 T 28-03-2018 MKLM6_RS00900 e89a67a8dabc5a79847c90b38cb42722 210 SMART SM00448 2 115 2.9E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS00900 e89a67a8dabc5a79847c90b38cb42722 210 SMART SM00421 146 203 5.0E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS18220 bf23aa02002861d513d5b6c00d35e20c 745 SUPERFAMILY SSF101904 496 739 1.31E-49 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal MKLM6_RS18220 bf23aa02002861d513d5b6c00d35e20c 745 Gene3D G3DSA:3.90.199.10 33 215 1.1E-74 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS18220 bf23aa02002861d513d5b6c00d35e20c 745 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 594 631 0.018 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS18220 bf23aa02002861d513d5b6c00d35e20c 745 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 643 694 4.7E-5 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS18220 bf23aa02002861d513d5b6c00d35e20c 745 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 8 740 0.0 T 28-03-2018 MKLM6_RS18220 bf23aa02002861d513d5b6c00d35e20c 745 Gene3D G3DSA:3.30.1360.40 237 330 5.8E-23 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 MKLM6_RS18220 bf23aa02002861d513d5b6c00d35e20c 745 SMART SM00434 10 460 4.2E-232 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS18220 bf23aa02002861d513d5b6c00d35e20c 745 Gene3D G3DSA:1.10.268.10 343 482 1.0E-44 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS18220 bf23aa02002861d513d5b6c00d35e20c 745 Gene3D G3DSA:2.120.10.90 493 741 2.9E-45 T 28-03-2018 MKLM6_RS18220 bf23aa02002861d513d5b6c00d35e20c 745 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 3 741 33.483 T 28-03-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS18220 bf23aa02002861d513d5b6c00d35e20c 745 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 31 467 8.6E-135 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS18220 bf23aa02002861d513d5b6c00d35e20c 745 SUPERFAMILY SSF56719 30 482 4.97E-155 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MKLM6_RS11245 dae06a99d07929166ae17204f65b3fa8 402 SUPERFAMILY SSF53756 2 365 1.07E-28 T 28-03-2018 MKLM6_RS11245 dae06a99d07929166ae17204f65b3fa8 402 Pfam PF13692 Glycosyl transferases group 1 196 332 1.5E-21 T 28-03-2018 MKLM6_RS11245 dae06a99d07929166ae17204f65b3fa8 402 Gene3D G3DSA:3.40.50.2000 189 352 1.8E-17 T 28-03-2018 MKLM6_RS17640 ff992ddfaf8a23acb22d53c5d887a290 514 SUPERFAMILY SSF142984 340 420 3.14E-22 T 28-03-2018 MKLM6_RS17640 ff992ddfaf8a23acb22d53c5d887a290 514 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 426 508 1.1E-29 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS17640 ff992ddfaf8a23acb22d53c5d887a290 514 Pfam PF10531 SLBB domain 341 384 2.2E-7 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS17640 ff992ddfaf8a23acb22d53c5d887a290 514 SUPERFAMILY SSF142019 96 336 2.09E-85 T 28-03-2018 MKLM6_RS17640 ff992ddfaf8a23acb22d53c5d887a290 514 SUPERFAMILY SSF140490 422 509 1.7E-28 T 28-03-2018 MKLM6_RS17640 ff992ddfaf8a23acb22d53c5d887a290 514 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 438 449 - T 28-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS17640 ff992ddfaf8a23acb22d53c5d887a290 514 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 144 315 1.5E-43 T 28-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS17640 ff992ddfaf8a23acb22d53c5d887a290 514 SUPERFAMILY SSF52833 4 87 6.26E-7 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS17640 ff992ddfaf8a23acb22d53c5d887a290 514 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 263 278 - T 28-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS17640 ff992ddfaf8a23acb22d53c5d887a290 514 Gene3D G3DSA:3.40.30.10 5 97 8.6E-5 T 28-03-2018 MKLM6_RS17640 ff992ddfaf8a23acb22d53c5d887a290 514 SMART SM00928 425 470 1.1E-17 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS19240 d0a3a0d2d1810826a85d408d0e8588e5 75 Gene3D G3DSA:3.40.50.1010 1 70 2.1E-5 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS19240 d0a3a0d2d1810826a85d408d0e8588e5 75 SUPERFAMILY SSF88723 10 70 7.36E-7 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS01035 ce8dfc492740f6b60b7bfba0af156bb7 196 Gene3D G3DSA:1.10.530.10 33 195 1.8E-19 T 28-03-2018 MKLM6_RS01035 ce8dfc492740f6b60b7bfba0af156bb7 196 SUPERFAMILY SSF53955 18 181 5.2E-22 T 28-03-2018 IPR023346 Lysozyme-like domain MKLM6_RS00195 414a704b773b83bb9e3316dfc43407d9 253 Pfam PF01061 ABC-2 type transporter 6 216 2.1E-31 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MKLM6_RS00195 414a704b773b83bb9e3316dfc43407d9 253 PIRSF PIRSF006648 7 250 2.0E-29 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MKLM6_RS00195 414a704b773b83bb9e3316dfc43407d9 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 173 192 5.5E-11 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MKLM6_RS00195 414a704b773b83bb9e3316dfc43407d9 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 193 212 5.5E-11 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MKLM6_RS00195 414a704b773b83bb9e3316dfc43407d9 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 99 124 5.5E-11 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MKLM6_RS00195 414a704b773b83bb9e3316dfc43407d9 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 55 77 5.5E-11 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MKLM6_RS03460 9babeec116e10f1d36dbfc10987f2166 96 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 24.893 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MKLM6_RS03460 9babeec116e10f1d36dbfc10987f2166 96 SUPERFAMILY SSF50129 1 94 8.01E-32 T 28-03-2018 IPR011032 GroES-like MKLM6_RS03460 9babeec116e10f1d36dbfc10987f2166 96 Gene3D G3DSA:2.30.33.40 1 95 5.8E-35 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MKLM6_RS03460 9babeec116e10f1d36dbfc10987f2166 96 PRINTS PR00297 10kDa chaperonin signature 25 46 2.0E-29 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MKLM6_RS03460 9babeec116e10f1d36dbfc10987f2166 96 PRINTS PR00297 10kDa chaperonin signature 3 18 2.0E-29 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MKLM6_RS03460 9babeec116e10f1d36dbfc10987f2166 96 PRINTS PR00297 10kDa chaperonin signature 60 72 2.0E-29 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MKLM6_RS03460 9babeec116e10f1d36dbfc10987f2166 96 PRINTS PR00297 10kDa chaperonin signature 81 94 2.0E-29 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MKLM6_RS03460 9babeec116e10f1d36dbfc10987f2166 96 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 28-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 MKLM6_RS03460 9babeec116e10f1d36dbfc10987f2166 96 SMART SM00883 2 94 4.3E-51 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MKLM6_RS03460 9babeec116e10f1d36dbfc10987f2166 96 Pfam PF00166 Chaperonin 10 Kd subunit 3 93 3.4E-31 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MKLM6_RS17950 e0ceb2d67333ae239f09c0d39281b8d6 446 Pfam PF10396 GTP-binding protein TrmE N-terminus 6 120 3.9E-35 T 28-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 MKLM6_RS17950 e0ceb2d67333ae239f09c0d39281b8d6 446 Gene3D G3DSA:1.20.120.430 122 279 2.4E-23 T 28-03-2018 MKLM6_RS17950 e0ceb2d67333ae239f09c0d39281b8d6 446 Gene3D G3DSA:3.30.1360.120 1 121 4.9E-41 T 28-03-2018 MKLM6_RS17950 e0ceb2d67333ae239f09c0d39281b8d6 446 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 217 334 1.1E-18 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MKLM6_RS17950 e0ceb2d67333ae239f09c0d39281b8d6 446 Pfam PF01926 50S ribosome-binding GTPase 219 315 1.0E-22 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS17950 e0ceb2d67333ae239f09c0d39281b8d6 446 SUPERFAMILY SSF52540 204 365 8.5E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS17950 e0ceb2d67333ae239f09c0d39281b8d6 446 SUPERFAMILY SSF52540 73 170 8.5E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS17950 e0ceb2d67333ae239f09c0d39281b8d6 446 Pfam PF12631 MnmE helical domain 123 443 1.9E-55 T 28-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 MKLM6_RS17950 e0ceb2d67333ae239f09c0d39281b8d6 446 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 5 446 32.013 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 MKLM6_RS17950 e0ceb2d67333ae239f09c0d39281b8d6 446 SUPERFAMILY SSF116878 121 220 7.32E-48 T 28-03-2018 MKLM6_RS17950 e0ceb2d67333ae239f09c0d39281b8d6 446 SUPERFAMILY SSF116878 372 446 7.32E-48 T 28-03-2018 MKLM6_RS17950 e0ceb2d67333ae239f09c0d39281b8d6 446 Gene3D G3DSA:1.20.120.430 280 446 5.6E-30 T 28-03-2018 MKLM6_RS17950 e0ceb2d67333ae239f09c0d39281b8d6 446 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 446 3.5E-97 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 MKLM6_RS05590 910ef8949968b3781001fd4fa09f26c1 142 Gene3D G3DSA:3.10.50.30 45 142 1.1E-18 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MKLM6_RS05590 910ef8949968b3781001fd4fa09f26c1 142 Pfam PF14760 Rnk N-terminus 8 50 2.2E-6 T 28-03-2018 IPR029462 Regulator of nucleoside diphosphate kinase, N-terminal domain MKLM6_RS05590 910ef8949968b3781001fd4fa09f26c1 142 SUPERFAMILY SSF54534 57 132 2.62E-16 T 28-03-2018 MKLM6_RS05590 910ef8949968b3781001fd4fa09f26c1 142 Gene3D G3DSA:1.10.286.20 9 44 8.3E-8 T 28-03-2018 MKLM6_RS05590 910ef8949968b3781001fd4fa09f26c1 142 PIRSF PIRSF006092 25 134 5.9E-22 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 MKLM6_RS05590 910ef8949968b3781001fd4fa09f26c1 142 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 60 130 7.8E-19 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MKLM6_RS01135 2e414eab57ad4062b8759d7d7a42d370 357 Gene3D G3DSA:3.20.20.210 1 357 4.3E-114 T 28-03-2018 MKLM6_RS01135 2e414eab57ad4062b8759d7d7a42d370 357 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 5 347 1.3E-139 T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MKLM6_RS01135 2e414eab57ad4062b8759d7d7a42d370 357 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 6 349 50.249 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MKLM6_RS01135 2e414eab57ad4062b8759d7d7a42d370 357 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 142 158 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MKLM6_RS01135 2e414eab57ad4062b8759d7d7a42d370 357 SUPERFAMILY SSF51726 2 352 5.89E-122 T 28-03-2018 MKLM6_RS01135 2e414eab57ad4062b8759d7d7a42d370 357 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 9 347 7.2E-133 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MKLM6_RS10260 086f7b5e463df11ed310cb58ce0d67f2 258 Gene3D G3DSA:3.90.550.10 3 255 2.9E-25 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS10260 086f7b5e463df11ed310cb58ce0d67f2 258 SUPERFAMILY SSF53448 4 217 1.97E-37 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS10260 086f7b5e463df11ed310cb58ce0d67f2 258 Pfam PF00535 Glycosyl transferase family 2 9 168 6.6E-19 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MKLM6_RS17325 fa1f797feada489b27c3b8acb816b129 545 Gene3D G3DSA:1.10.275.10 40 237 4.2E-61 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal MKLM6_RS17325 fa1f797feada489b27c3b8acb816b129 545 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 179 195 - T 28-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 MKLM6_RS17325 fa1f797feada489b27c3b8acb816b129 545 SUPERFAMILY SSF48557 31 542 3.77E-173 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 MKLM6_RS17325 fa1f797feada489b27c3b8acb816b129 545 Pfam PF00221 Aromatic amino acid lyase 49 514 2.0E-162 T 28-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 MKLM6_RS17325 fa1f797feada489b27c3b8acb816b129 545 Gene3D G3DSA:1.20.200.10 238 543 4.0E-105 T 28-03-2018 MKLM6_RS03205 3130fd4f89a4f51af19752b9712f0a62 275 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 6 267 1.1E-81 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 MKLM6_RS03205 3130fd4f89a4f51af19752b9712f0a62 275 PIRSF PIRSF000193 3 271 1.1E-79 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 MKLM6_RS03205 3130fd4f89a4f51af19752b9712f0a62 275 Gene3D G3DSA:1.10.3730.10 166 273 3.6E-37 T 28-03-2018 MKLM6_RS03205 3130fd4f89a4f51af19752b9712f0a62 275 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 4 268 26.475 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 MKLM6_RS03205 3130fd4f89a4f51af19752b9712f0a62 275 SUPERFAMILY SSF48179 163 272 1.7E-34 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MKLM6_RS03205 3130fd4f89a4f51af19752b9712f0a62 275 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 164 268 2.6E-33 T 28-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MKLM6_RS03205 3130fd4f89a4f51af19752b9712f0a62 275 SUPERFAMILY SSF51735 4 160 5.88E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS03205 3130fd4f89a4f51af19752b9712f0a62 275 Gene3D G3DSA:3.40.50.720 1 165 4.8E-35 T 28-03-2018 MKLM6_RS03205 3130fd4f89a4f51af19752b9712f0a62 275 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 5 100 3.0E-22 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal MKLM6_RS15760 1058a1a4b24fbed2992c272398ca7b17 384 SUPERFAMILY SSF53756 5 379 1.92E-118 T 28-03-2018 MKLM6_RS15760 1058a1a4b24fbed2992c272398ca7b17 384 Gene3D G3DSA:3.40.50.2000 1 219 8.0E-70 T 28-03-2018 MKLM6_RS15760 1058a1a4b24fbed2992c272398ca7b17 384 Gene3D G3DSA:3.40.50.2000 220 355 1.0E-35 T 28-03-2018 MKLM6_RS15760 1058a1a4b24fbed2992c272398ca7b17 384 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 28 378 4.5E-110 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 MKLM6_RS15760 1058a1a4b24fbed2992c272398ca7b17 384 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 7 380 5.9E-128 T 28-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 MKLM6_RS05350 cc01e1f95fe0478d66ea48d146922459 365 Gene3D G3DSA:3.30.1360.120 3 135 2.3E-28 T 28-03-2018 MKLM6_RS05350 cc01e1f95fe0478d66ea48d146922459 365 Gene3D G3DSA:3.30.1360.120 136 231 3.7E-26 T 28-03-2018 MKLM6_RS05350 cc01e1f95fe0478d66ea48d146922459 365 SUPERFAMILY SSF103025 3 273 2.83E-84 T 28-03-2018 MKLM6_RS05350 cc01e1f95fe0478d66ea48d146922459 365 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 5 357 3.2E-107 T 28-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 MKLM6_RS05350 cc01e1f95fe0478d66ea48d146922459 365 PIRSF PIRSF006487 1 365 9.8E-80 T 28-03-2018 MKLM6_RS05350 cc01e1f95fe0478d66ea48d146922459 365 Pfam PF01571 Aminomethyltransferase folate-binding domain 10 253 5.6E-85 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal MKLM6_RS05350 cc01e1f95fe0478d66ea48d146922459 365 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 261 352 9.0E-21 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MKLM6_RS05350 cc01e1f95fe0478d66ea48d146922459 365 SUPERFAMILY SSF101790 268 362 2.45E-24 T 28-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain MKLM6_RS05350 cc01e1f95fe0478d66ea48d146922459 365 Gene3D G3DSA:2.40.30.110 276 365 3.4E-24 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MKLM6_RS05350 cc01e1f95fe0478d66ea48d146922459 365 Gene3D G3DSA:4.10.1250.10 232 273 3.2E-17 T 28-03-2018 MKLM6_RS12145 bd5abc2284f5358bebd5bb2736fc90ca 404 TIGRFAM TIGR02570 cas7_GSU0053: CRISPR-associated protein GSU0053/csb1, Dpsyc system 27 190 3.2E-18 T 28-03-2018 IPR013403 CRISPR-associated protein GSU0053 MKLM6_RS12145 bd5abc2284f5358bebd5bb2736fc90ca 404 Pfam PF09617 CRISPR-associated protein GSU0053 (Cas_GSU0053) 25 194 1.2E-50 T 28-03-2018 IPR013403 CRISPR-associated protein GSU0053 MKLM6_RS22260 71c0c1d786b5a11ceb6b8a7b7472ecab 206 Pfam PF02796 Helix-turn-helix domain of resolvase 147 187 5.6E-10 T 28-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 MKLM6_RS22260 71c0c1d786b5a11ceb6b8a7b7472ecab 206 SUPERFAMILY SSF46689 147 189 1.49E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS22260 71c0c1d786b5a11ceb6b8a7b7472ecab 206 SMART SM00857 4 145 1.6E-49 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MKLM6_RS22260 71c0c1d786b5a11ceb6b8a7b7472ecab 206 Pfam PF00239 Resolvase, N terminal domain 4 144 2.3E-39 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MKLM6_RS22260 71c0c1d786b5a11ceb6b8a7b7472ecab 206 Gene3D G3DSA:3.40.50.1390 1 114 1.3E-33 T 28-03-2018 MKLM6_RS22260 71c0c1d786b5a11ceb6b8a7b7472ecab 206 SUPERFAMILY SSF53041 3 144 5.1E-38 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MKLM6_RS22260 71c0c1d786b5a11ceb6b8a7b7472ecab 206 Gene3D G3DSA:1.10.10.60 145 191 5.0E-8 T 28-03-2018 MKLM6_RS22260 71c0c1d786b5a11ceb6b8a7b7472ecab 206 ProSitePatterns PS00398 Site-specific recombinases signature 2. 63 75 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 MKLM6_RS22260 71c0c1d786b5a11ceb6b8a7b7472ecab 206 Gene3D G3DSA:1.20.5.40 115 143 3.1E-15 T 28-03-2018 MKLM6_RS22260 71c0c1d786b5a11ceb6b8a7b7472ecab 206 ProSitePatterns PS00397 Site-specific recombinases active site. 7 15 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 MKLM6_RS13175 6f8a80cfd28358b653d7ea66f680f6a7 846 SUPERFAMILY SSF48334 257 554 8.24E-88 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 MKLM6_RS13175 6f8a80cfd28358b653d7ea66f680f6a7 846 Pfam PF01624 MutS domain I 1 109 1.3E-39 T 28-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 MKLM6_RS13175 6f8a80cfd28358b653d7ea66f680f6a7 846 SUPERFAMILY SSF52540 556 787 2.08E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS13175 6f8a80cfd28358b653d7ea66f680f6a7 846 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 1 833 24.745 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 MKLM6_RS13175 6f8a80cfd28358b653d7ea66f680f6a7 846 Gene3D G3DSA:1.10.1420.10 253 396 7.1E-35 T 28-03-2018 MKLM6_RS13175 6f8a80cfd28358b653d7ea66f680f6a7 846 Pfam PF05190 MutS family domain IV 417 507 1.2E-30 T 28-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 MKLM6_RS13175 6f8a80cfd28358b653d7ea66f680f6a7 846 SMART SM00533 273 580 1.8E-99 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 MKLM6_RS13175 6f8a80cfd28358b653d7ea66f680f6a7 846 PIRSF PIRSF037677 204 814 3.5E-126 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 MKLM6_RS13175 6f8a80cfd28358b653d7ea66f680f6a7 846 PIRSF PIRSF037677 1 178 6.7E-25 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 MKLM6_RS13175 6f8a80cfd28358b653d7ea66f680f6a7 846 Gene3D G3DSA:3.40.50.300 556 809 2.4E-42 T 28-03-2018 MKLM6_RS13175 6f8a80cfd28358b653d7ea66f680f6a7 846 Gene3D G3DSA:3.30.420.110 118 252 8.3E-29 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 MKLM6_RS13175 6f8a80cfd28358b653d7ea66f680f6a7 846 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 677 693 - T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MKLM6_RS13175 6f8a80cfd28358b653d7ea66f680f6a7 846 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 1 837 0.0 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 MKLM6_RS13175 6f8a80cfd28358b653d7ea66f680f6a7 846 Gene3D G3DSA:3.40.1170.10 1 117 7.6E-43 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 MKLM6_RS13175 6f8a80cfd28358b653d7ea66f680f6a7 846 Gene3D G3DSA:1.10.1420.10 397 524 5.4E-32 T 28-03-2018 MKLM6_RS13175 6f8a80cfd28358b653d7ea66f680f6a7 846 SUPERFAMILY SSF55271 1 105 3.01E-38 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 MKLM6_RS13175 6f8a80cfd28358b653d7ea66f680f6a7 846 Pfam PF05188 MutS domain II 118 243 5.4E-27 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 MKLM6_RS13175 6f8a80cfd28358b653d7ea66f680f6a7 846 SUPERFAMILY SSF53150 104 255 2.09E-43 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 MKLM6_RS13175 6f8a80cfd28358b653d7ea66f680f6a7 846 SMART SM00534 596 783 1.2E-116 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MKLM6_RS13175 6f8a80cfd28358b653d7ea66f680f6a7 846 Pfam PF00488 MutS domain V 599 786 1.8E-85 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MKLM6_RS13175 6f8a80cfd28358b653d7ea66f680f6a7 846 Pfam PF05192 MutS domain III 260 548 1.8E-37 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 MKLM6_RS05185 3a76fe7c8f672dffd079dea016d884dd 88 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 5 85 4.2E-24 T 28-03-2018 IPR017924 RNA-binding protein YhbY GO:0003723 MKLM6_RS05185 3a76fe7c8f672dffd079dea016d884dd 88 SUPERFAMILY SSF75471 4 87 6.15E-24 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 MKLM6_RS05185 3a76fe7c8f672dffd079dea016d884dd 88 Gene3D G3DSA:3.30.110.60 2 88 8.1E-21 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 MKLM6_RS05185 3a76fe7c8f672dffd079dea016d884dd 88 Pfam PF01985 CRS1 / YhbY (CRM) domain 5 83 7.0E-20 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 MKLM6_RS05185 3a76fe7c8f672dffd079dea016d884dd 88 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 17 88 1.0E-17 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 MKLM6_RS05185 3a76fe7c8f672dffd079dea016d884dd 88 SMART SM01103 1 83 1.0E-34 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 MKLM6_RS08470 49b70a361d5a5ba57852249513a95423 270 Pfam PF01226 Formate/nitrite transporter 8 257 9.0E-63 T 28-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 MKLM6_RS08470 49b70a361d5a5ba57852249513a95423 270 Gene3D G3DSA:1.20.1080.10 4 270 1.0E-66 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MKLM6_RS14405 2d7b7ebea491986d8367a2f46bbfdcf5 365 Pfam PF01609 Transposase DDE domain 199 346 8.4E-14 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS14405 2d7b7ebea491986d8367a2f46bbfdcf5 365 Pfam PF05598 Transposase domain (DUF772) 53 128 2.5E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS00720 2d7b7ebea491986d8367a2f46bbfdcf5 365 Pfam PF01609 Transposase DDE domain 199 346 8.4E-14 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS00720 2d7b7ebea491986d8367a2f46bbfdcf5 365 Pfam PF05598 Transposase domain (DUF772) 53 128 2.5E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS12155 ed9cc6d3eaf1cea8afbf7343b09b4e6b 961 Gene3D G3DSA:1.10.3210.10 741 948 1.5E-10 T 28-03-2018 MKLM6_RS12155 ed9cc6d3eaf1cea8afbf7343b09b4e6b 961 TIGRFAM TIGR02621 cas3_GSU0051: CRISPR-associated helicase Cas3, subtype Dpsyc 4 522 2.2E-113 T 28-03-2018 IPR013444 Helicase Cas3, CRISPR-associated, Anaes-subtype MKLM6_RS12155 ed9cc6d3eaf1cea8afbf7343b09b4e6b 961 Gene3D G3DSA:3.40.50.300 2 258 2.1E-11 T 28-03-2018 MKLM6_RS12155 ed9cc6d3eaf1cea8afbf7343b09b4e6b 961 Pfam PF01966 HD domain 761 881 1.3E-5 T 28-03-2018 IPR006674 HD domain MKLM6_RS12155 ed9cc6d3eaf1cea8afbf7343b09b4e6b 961 SUPERFAMILY SSF52540 132 406 2.04E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS12155 ed9cc6d3eaf1cea8afbf7343b09b4e6b 961 SUPERFAMILY SSF52540 38 93 2.04E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS12155 ed9cc6d3eaf1cea8afbf7343b09b4e6b 961 SUPERFAMILY SSF109604 839 884 6.04E-7 T 28-03-2018 MKLM6_RS12155 ed9cc6d3eaf1cea8afbf7343b09b4e6b 961 SUPERFAMILY SSF109604 762 800 6.04E-7 T 28-03-2018 MKLM6_RS12155 ed9cc6d3eaf1cea8afbf7343b09b4e6b 961 Gene3D G3DSA:3.40.50.300 278 428 4.4E-6 T 28-03-2018 MKLM6_RS12155 ed9cc6d3eaf1cea8afbf7343b09b4e6b 961 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 760 919 4.8E-16 T 28-03-2018 IPR006483 CRISPR-associated Cas3-HD domain MKLM6_RS12155 ed9cc6d3eaf1cea8afbf7343b09b4e6b 961 SMART SM00471 756 928 0.0013 T 28-03-2018 IPR003607 HD/PDEase domain MKLM6_RS12840 81fb100cb3412e873d0a956f8013fc3c 204 Gene3D G3DSA:1.10.10.10 115 204 3.3E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS12840 81fb100cb3412e873d0a956f8013fc3c 204 SUPERFAMILY SSF53155 37 113 2.55E-13 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MKLM6_RS12840 81fb100cb3412e873d0a956f8013fc3c 204 Gene3D G3DSA:3.30.160.70 24 114 1.3E-10 T 28-03-2018 MKLM6_RS12840 81fb100cb3412e873d0a956f8013fc3c 204 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 117 196 7.0E-28 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MKLM6_RS12840 81fb100cb3412e873d0a956f8013fc3c 204 SUPERFAMILY SSF46767 116 197 5.89E-26 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MKLM6_RS12840 81fb100cb3412e873d0a956f8013fc3c 204 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 118 197 3.4E-27 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MKLM6_RS19740 f584db3fdb5bd07157b76004193a57fb 605 SUPERFAMILY SSF52172 482 597 1.57E-17 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS19740 f584db3fdb5bd07157b76004193a57fb 605 SUPERFAMILY SSF47384 218 300 9.81E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS19740 f584db3fdb5bd07157b76004193a57fb 605 Gene3D G3DSA:3.30.565.10 304 468 2.8E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS19740 f584db3fdb5bd07157b76004193a57fb 605 Gene3D G3DSA:1.10.287.130 225 296 1.8E-9 T 28-03-2018 MKLM6_RS19740 f584db3fdb5bd07157b76004193a57fb 605 Gene3D G3DSA:3.40.50.2300 477 604 1.4E-15 T 28-03-2018 MKLM6_RS19740 f584db3fdb5bd07157b76004193a57fb 605 SUPERFAMILY SSF55874 289 456 1.57E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS19740 f584db3fdb5bd07157b76004193a57fb 605 SMART SM00387 346 457 2.8E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS19740 f584db3fdb5bd07157b76004193a57fb 605 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 410 3.0E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS19740 f584db3fdb5bd07157b76004193a57fb 605 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 396 3.0E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS19740 f584db3fdb5bd07157b76004193a57fb 605 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 435 3.0E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS19740 f584db3fdb5bd07157b76004193a57fb 605 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 454 3.0E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS19740 f584db3fdb5bd07157b76004193a57fb 605 SMART SM00388 235 300 1.3E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS19740 f584db3fdb5bd07157b76004193a57fb 605 Pfam PF00072 Response regulator receiver domain 484 592 2.0E-9 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS19740 f584db3fdb5bd07157b76004193a57fb 605 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 347 455 4.1E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS19740 f584db3fdb5bd07157b76004193a57fb 605 Pfam PF00512 His Kinase A (phospho-acceptor) domain 235 299 1.4E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS19740 f584db3fdb5bd07157b76004193a57fb 605 SMART SM00448 481 593 8.4E-10 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS03780 12f5c189c09eaf254adb56ec6197458d 147 Gene3D G3DSA:3.30.70.920 52 141 2.3E-8 T 28-03-2018 MKLM6_RS06825 d45db265d7cbdf56912b242b4223c3f3 1123 SUPERFAMILY SSF55874 729 894 1.01E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS06825 d45db265d7cbdf56912b242b4223c3f3 1123 SUPERFAMILY SSF47384 661 741 6.08E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS06825 d45db265d7cbdf56912b242b4223c3f3 1123 SMART SM00388 674 740 1.5E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS06825 d45db265d7cbdf56912b242b4223c3f3 1123 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 787 896 1.8E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS06825 d45db265d7cbdf56912b242b4223c3f3 1123 Gene3D G3DSA:3.40.50.2300 915 1120 2.0E-36 T 28-03-2018 MKLM6_RS06825 d45db265d7cbdf56912b242b4223c3f3 1123 Pfam PF00072 Response regulator receiver domain 921 1030 1.1E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS06825 d45db265d7cbdf56912b242b4223c3f3 1123 PRINTS PR00344 Bacterial sensor protein C-terminal signature 823 837 1.9E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS06825 d45db265d7cbdf56912b242b4223c3f3 1123 PRINTS PR00344 Bacterial sensor protein C-terminal signature 858 876 1.9E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS06825 d45db265d7cbdf56912b242b4223c3f3 1123 PRINTS PR00344 Bacterial sensor protein C-terminal signature 882 895 1.9E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS06825 d45db265d7cbdf56912b242b4223c3f3 1123 PRINTS PR00344 Bacterial sensor protein C-terminal signature 841 851 1.9E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS06825 d45db265d7cbdf56912b242b4223c3f3 1123 Gene3D G3DSA:3.30.450.20 334 677 8.9E-5 T 28-03-2018 MKLM6_RS06825 d45db265d7cbdf56912b242b4223c3f3 1123 Pfam PF00512 His Kinase A (phospho-acceptor) domain 674 739 1.8E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS06825 d45db265d7cbdf56912b242b4223c3f3 1123 Gene3D G3DSA:3.30.565.10 735 898 1.2E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS06825 d45db265d7cbdf56912b242b4223c3f3 1123 Gene3D G3DSA:1.10.287.130 678 734 9.5E-18 T 28-03-2018 MKLM6_RS06825 d45db265d7cbdf56912b242b4223c3f3 1123 SMART SM00448 919 1030 4.2E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS06825 d45db265d7cbdf56912b242b4223c3f3 1123 SMART SM00387 787 898 7.2E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS06825 d45db265d7cbdf56912b242b4223c3f3 1123 SUPERFAMILY SSF52172 918 1044 5.98E-36 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS21325 504099bc2ea7bfc52b5a0fb2615804d0 247 Pfam PF00912 Transglycosylase 79 242 1.7E-50 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 MKLM6_RS21325 504099bc2ea7bfc52b5a0fb2615804d0 247 SUPERFAMILY SSF53955 63 244 2.81E-59 T 28-03-2018 IPR023346 Lysozyme-like domain MKLM6_RS21325 504099bc2ea7bfc52b5a0fb2615804d0 247 Gene3D G3DSA:1.10.3810.10 66 246 2.6E-56 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 MKLM6_RS21325 504099bc2ea7bfc52b5a0fb2615804d0 247 Hamap MF_00766 Monofunctional biosynthetic peptidoglycan transglycosylase [mtgA]. 24 247 38.538 T 28-03-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 MKLM6_RS21325 504099bc2ea7bfc52b5a0fb2615804d0 247 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 31 244 2.5E-78 T 28-03-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 MKLM6_RS11055 5309bf18a9211aa9af2cd3cda35e325f 524 Gene3D G3DSA:3.60.110.10 211 470 2.1E-31 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS11055 5309bf18a9211aa9af2cd3cda35e325f 524 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 5 508 16.776 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 MKLM6_RS11055 5309bf18a9211aa9af2cd3cda35e325f 524 SUPERFAMILY SSF56317 222 467 1.26E-32 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS11055 5309bf18a9211aa9af2cd3cda35e325f 524 Pfam PF00795 Carbon-nitrogen hydrolase 266 461 8.8E-19 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS11055 5309bf18a9211aa9af2cd3cda35e325f 524 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 60 459 5.2E-72 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 MKLM6_RS20340 af27b2032215e87aebf1f3591c44572e 249 Gene3D G3DSA:1.20.1450.10 26 240 8.1E-106 T 28-03-2018 IPR003393 Ammonia monooxygenase/particulate methane monooxygenase, subunit A MKLM6_RS20340 af27b2032215e87aebf1f3591c44572e 249 TIGRFAM TIGR03080 CH4_NH3mon_ox_A: methane monooxygenase/ammonia monooxygenase, subunit A 5 241 2.8E-105 T 28-03-2018 IPR003393 Ammonia monooxygenase/particulate methane monooxygenase, subunit A MKLM6_RS20340 af27b2032215e87aebf1f3591c44572e 249 Pfam PF02461 Ammonia monooxygenase 9 244 2.8E-122 T 28-03-2018 IPR003393 Ammonia monooxygenase/particulate methane monooxygenase, subunit A MKLM6_RS15425 3c323a71f59ac2b44d5f31e03e45c432 455 SMART SM00448 5 119 1.2E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS15425 3c323a71f59ac2b44d5f31e03e45c432 455 Gene3D G3DSA:1.10.8.60 316 402 6.6E-20 T 28-03-2018 MKLM6_RS15425 3c323a71f59ac2b44d5f31e03e45c432 455 Gene3D G3DSA:3.40.50.2300 2 140 2.2E-24 T 28-03-2018 MKLM6_RS15425 3c323a71f59ac2b44d5f31e03e45c432 455 Pfam PF00158 Sigma-54 interaction domain 145 309 7.6E-70 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MKLM6_RS15425 3c323a71f59ac2b44d5f31e03e45c432 455 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 168 181 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MKLM6_RS15425 3c323a71f59ac2b44d5f31e03e45c432 455 Pfam PF00072 Response regulator receiver domain 8 115 2.6E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS15425 3c323a71f59ac2b44d5f31e03e45c432 455 Gene3D G3DSA:1.10.10.60 403 447 9.3E-14 T 28-03-2018 MKLM6_RS15425 3c323a71f59ac2b44d5f31e03e45c432 455 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 230 245 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MKLM6_RS15425 3c323a71f59ac2b44d5f31e03e45c432 455 Gene3D G3DSA:3.40.50.300 141 315 1.3E-28 T 28-03-2018 MKLM6_RS15425 3c323a71f59ac2b44d5f31e03e45c432 455 SUPERFAMILY SSF46689 357 445 5.08E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS15425 3c323a71f59ac2b44d5f31e03e45c432 455 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 409 426 1.7E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS15425 3c323a71f59ac2b44d5f31e03e45c432 455 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 426 446 1.7E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS15425 3c323a71f59ac2b44d5f31e03e45c432 455 SMART SM00382 164 307 1.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS15425 3c323a71f59ac2b44d5f31e03e45c432 455 SUPERFAMILY SSF52540 144 386 3.8E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS15425 3c323a71f59ac2b44d5f31e03e45c432 455 SUPERFAMILY SSF52172 7 189 7.68E-32 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS15425 3c323a71f59ac2b44d5f31e03e45c432 455 Pfam PF02954 Bacterial regulatory protein, Fis family 403 437 1.6E-9 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS15425 3c323a71f59ac2b44d5f31e03e45c432 455 TIGRFAM TIGR02915 PEP_resp_reg: PEP-CTERM-box response regulator transcription factor 7 445 4.6E-210 T 28-03-2018 IPR014264 Signal transduction response regulator, PEP-CTERM system, putative MKLM6_RS13700 e4664dbe82be6d3d8bb16b9172b081d4 313 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 2 312 6.7E-134 T 28-03-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 MKLM6_RS13700 e4664dbe82be6d3d8bb16b9172b081d4 313 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 241 1.9E-48 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MKLM6_RS13700 e4664dbe82be6d3d8bb16b9172b081d4 313 Gene3D G3DSA:3.40.50.720 1 165 3.5E-14 T 28-03-2018 MKLM6_RS13700 e4664dbe82be6d3d8bb16b9172b081d4 313 Gene3D G3DSA:3.90.25.10 166 313 4.0E-27 T 28-03-2018 MKLM6_RS13700 e4664dbe82be6d3d8bb16b9172b081d4 313 SUPERFAMILY SSF51735 2 311 9.76E-62 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS13700 e4664dbe82be6d3d8bb16b9172b081d4 313 Hamap MF_01601 ADP-L-glycero-D-manno-heptose-6-epimerase [hldD]. 1 313 49.97 T 28-03-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 MKLM6_RS03690 0b44697a0172eeb455e257ef1c24897c 95 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 28.111 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MKLM6_RS03690 0b44697a0172eeb455e257ef1c24897c 95 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 1.6E-37 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MKLM6_RS03690 0b44697a0172eeb455e257ef1c24897c 95 SMART SM00883 2 94 5.8E-61 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MKLM6_RS03690 0b44697a0172eeb455e257ef1c24897c 95 SUPERFAMILY SSF50129 1 94 1.02E-36 T 28-03-2018 IPR011032 GroES-like MKLM6_RS03690 0b44697a0172eeb455e257ef1c24897c 95 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 28-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 MKLM6_RS03690 0b44697a0172eeb455e257ef1c24897c 95 PRINTS PR00297 10kDa chaperonin signature 81 94 6.6E-34 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MKLM6_RS03690 0b44697a0172eeb455e257ef1c24897c 95 PRINTS PR00297 10kDa chaperonin signature 60 72 6.6E-34 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MKLM6_RS03690 0b44697a0172eeb455e257ef1c24897c 95 PRINTS PR00297 10kDa chaperonin signature 3 18 6.6E-34 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MKLM6_RS03690 0b44697a0172eeb455e257ef1c24897c 95 PRINTS PR00297 10kDa chaperonin signature 25 46 6.6E-34 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MKLM6_RS03690 0b44697a0172eeb455e257ef1c24897c 95 Gene3D G3DSA:2.30.33.40 1 95 2.1E-42 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MKLM6_RS03295 d7b049180553a6ae0b982c9d35837bbf 419 Gene3D G3DSA:3.40.228.10 217 277 3.1E-4 T 28-03-2018 MKLM6_RS03295 d7b049180553a6ae0b982c9d35837bbf 419 Gene3D G3DSA:3.40.50.1220 53 216 3.4E-17 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MKLM6_RS03295 d7b049180553a6ae0b982c9d35837bbf 419 PIRSF PIRSF005646 1 419 1.3E-48 T 28-03-2018 IPR016457 Formylmethanofuran dehydrogenase, subunit B GO:0015948|GO:0018493 KEGG: 00680+1.2.99.5|MetaCyc: PWY-5209|MetaCyc: PWY-7784 MKLM6_RS03295 d7b049180553a6ae0b982c9d35837bbf 419 TIGRFAM TIGR03129 one_C_dehyd_B: formylmethanofuran dehydrogenase subunit B 7 418 2.5E-101 T 28-03-2018 IPR016457 Formylmethanofuran dehydrogenase, subunit B GO:0015948|GO:0018493 KEGG: 00680+1.2.99.5|MetaCyc: PWY-5209|MetaCyc: PWY-7784 MKLM6_RS03295 d7b049180553a6ae0b982c9d35837bbf 419 SUPERFAMILY SSF53706 200 341 2.51E-11 T 28-03-2018 MKLM6_RS03295 d7b049180553a6ae0b982c9d35837bbf 419 SUPERFAMILY SSF53706 57 167 2.51E-11 T 28-03-2018 MKLM6_RS12170 39ef87d6ea8efd9d486de5ebe100edc2 102 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 41 2.2E-7 T 28-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 MKLM6_RS12170 39ef87d6ea8efd9d486de5ebe100edc2 102 Gene3D G3DSA:1.10.1220.10 2 47 2.1E-9 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 MKLM6_RS12170 39ef87d6ea8efd9d486de5ebe100edc2 102 SUPERFAMILY SSF47598 2 46 3.11E-6 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 MKLM6_RS20180 505f6a98b2dce0433339ab82e2dff1cc 152 SUPERFAMILY SSF53163 4 143 8.37E-28 T 28-03-2018 IPR023430 Peptidase HybD-like domain MKLM6_RS20180 505f6a98b2dce0433339ab82e2dff1cc 152 PRINTS PR00446 Hydrogen uptake protein signature 34 51 9.6E-7 T 28-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MKLM6_RS20180 505f6a98b2dce0433339ab82e2dff1cc 152 PRINTS PR00446 Hydrogen uptake protein signature 3 15 9.6E-7 T 28-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MKLM6_RS20180 505f6a98b2dce0433339ab82e2dff1cc 152 PRINTS PR00446 Hydrogen uptake protein signature 15 26 9.6E-7 T 28-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MKLM6_RS20180 505f6a98b2dce0433339ab82e2dff1cc 152 PRINTS PR00446 Hydrogen uptake protein signature 66 82 9.6E-7 T 28-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MKLM6_RS20180 505f6a98b2dce0433339ab82e2dff1cc 152 Pfam PF01750 Hydrogenase maturation protease 25 141 1.1E-11 T 28-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MKLM6_RS20180 505f6a98b2dce0433339ab82e2dff1cc 152 Gene3D G3DSA:3.40.50.1450 1 152 7.4E-32 T 28-03-2018 IPR023430 Peptidase HybD-like domain MKLM6_RS20180 505f6a98b2dce0433339ab82e2dff1cc 152 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 5 142 8.3E-28 T 28-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MKLM6_RS15985 43f42fa0d56a7cfd25bd9afc590ff984 558 Gene3D G3DSA:1.10.150.200 330 362 5.8E-8 T 28-03-2018 MKLM6_RS15985 43f42fa0d56a7cfd25bd9afc590ff984 558 Gene3D G3DSA:1.20.1250.10 22 129 4.0E-18 T 28-03-2018 MKLM6_RS15985 43f42fa0d56a7cfd25bd9afc590ff984 558 Gene3D G3DSA:1.20.1250.10 130 209 1.8E-21 T 28-03-2018 MKLM6_RS15985 43f42fa0d56a7cfd25bd9afc590ff984 558 Gene3D G3DSA:1.20.1250.10 363 424 1.2E-10 T 28-03-2018 MKLM6_RS15985 43f42fa0d56a7cfd25bd9afc590ff984 558 Gene3D G3DSA:1.20.1250.10 232 299 7.7E-18 T 28-03-2018 MKLM6_RS15985 43f42fa0d56a7cfd25bd9afc590ff984 558 Gene3D G3DSA:1.20.5.1140 300 329 0.014 T 28-03-2018 MKLM6_RS15985 43f42fa0d56a7cfd25bd9afc590ff984 558 SMART SM00028 51 84 15.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15985 43f42fa0d56a7cfd25bd9afc590ff984 558 SMART SM00028 97 130 80.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15985 43f42fa0d56a7cfd25bd9afc590ff984 558 SMART SM00028 189 222 25.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15985 43f42fa0d56a7cfd25bd9afc590ff984 558 SMART SM00028 373 406 230.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15985 43f42fa0d56a7cfd25bd9afc590ff984 558 SMART SM00028 143 176 35.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15985 43f42fa0d56a7cfd25bd9afc590ff984 558 SMART SM00028 327 360 0.03 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15985 43f42fa0d56a7cfd25bd9afc590ff984 558 SMART SM00028 281 314 260.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS15985 43f42fa0d56a7cfd25bd9afc590ff984 558 Pfam PF13374 Tetratricopeptide repeat 373 406 2.3E-6 T 28-03-2018 MKLM6_RS15985 43f42fa0d56a7cfd25bd9afc590ff984 558 Pfam PF13374 Tetratricopeptide repeat 235 268 3.4E-6 T 28-03-2018 MKLM6_RS15985 43f42fa0d56a7cfd25bd9afc590ff984 558 Pfam PF13374 Tetratricopeptide repeat 189 222 2.0E-9 T 28-03-2018 MKLM6_RS15985 43f42fa0d56a7cfd25bd9afc590ff984 558 Pfam PF13374 Tetratricopeptide repeat 143 176 4.1E-8 T 28-03-2018 MKLM6_RS15985 43f42fa0d56a7cfd25bd9afc590ff984 558 Pfam PF13424 Tetratricopeptide repeat 51 128 4.8E-8 T 28-03-2018 MKLM6_RS15985 43f42fa0d56a7cfd25bd9afc590ff984 558 Pfam PF13424 Tetratricopeptide repeat 284 358 1.9E-9 T 28-03-2018 MKLM6_RS15985 43f42fa0d56a7cfd25bd9afc590ff984 558 Gene3D G3DSA:1.10.287.1110 210 231 0.0073 T 28-03-2018 MKLM6_RS15985 43f42fa0d56a7cfd25bd9afc590ff984 558 SUPERFAMILY SSF48452 41 405 5.87E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS10165 3b904a1b5d06bec1d6a258508f2f1a49 366 Pfam PF01594 AI-2E family transporter 29 355 3.6E-65 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like MKLM6_RS04985 0d3671d5787dbf1b5da1d1db2de67a34 168 SUPERFAMILY SSF48452 35 76 3.22E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS04985 0d3671d5787dbf1b5da1d1db2de67a34 168 Gene3D G3DSA:1.25.40.10 14 163 9.2E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS06255 86c5080dd899e2d297f30ef1831e0016 1086 Gene3D G3DSA:3.30.2090.10 192 280 2.9E-16 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS06255 86c5080dd899e2d297f30ef1831e0016 1086 SUPERFAMILY SSF82714 196 276 5.36E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS06255 86c5080dd899e2d297f30ef1831e0016 1086 SUPERFAMILY SSF82693 51 145 3.14E-20 T 28-03-2018 MKLM6_RS06255 86c5080dd899e2d297f30ef1831e0016 1086 Pfam PF00873 AcrB/AcrD/AcrF family 25 1074 2.2E-151 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS06255 86c5080dd899e2d297f30ef1831e0016 1086 PRINTS PR00702 Acriflavin resistance protein family signature 497 520 3.6E-26 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS06255 86c5080dd899e2d297f30ef1831e0016 1086 PRINTS PR00702 Acriflavin resistance protein family signature 21 45 3.6E-26 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS06255 86c5080dd899e2d297f30ef1831e0016 1086 PRINTS PR00702 Acriflavin resistance protein family signature 364 387 3.6E-26 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS06255 86c5080dd899e2d297f30ef1831e0016 1086 PRINTS PR00702 Acriflavin resistance protein family signature 49 67 3.6E-26 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS06255 86c5080dd899e2d297f30ef1831e0016 1086 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 3.6E-26 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS06255 86c5080dd899e2d297f30ef1831e0016 1086 PRINTS PR00702 Acriflavin resistance protein family signature 418 442 3.6E-26 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS06255 86c5080dd899e2d297f30ef1831e0016 1086 Gene3D G3DSA:3.30.70.1430 51 152 6.9E-22 T 28-03-2018 MKLM6_RS06255 86c5080dd899e2d297f30ef1831e0016 1086 SUPERFAMILY SSF82693 592 706 3.3E-11 T 28-03-2018 MKLM6_RS06255 86c5080dd899e2d297f30ef1831e0016 1086 SUPERFAMILY SSF82866 323 524 7.85E-37 T 28-03-2018 MKLM6_RS06255 86c5080dd899e2d297f30ef1831e0016 1086 Gene3D G3DSA:3.30.70.1430 594 705 5.8E-18 T 28-03-2018 MKLM6_RS06255 86c5080dd899e2d297f30ef1831e0016 1086 Gene3D G3DSA:1.20.1640.10 847 1078 7.3E-27 T 28-03-2018 MKLM6_RS06255 86c5080dd899e2d297f30ef1831e0016 1086 Gene3D G3DSA:1.20.1640.10 304 525 5.8E-34 T 28-03-2018 MKLM6_RS06255 86c5080dd899e2d297f30ef1831e0016 1086 SUPERFAMILY SSF82693 301 354 1.2E-7 T 28-03-2018 MKLM6_RS06255 86c5080dd899e2d297f30ef1831e0016 1086 SUPERFAMILY SSF82693 152 193 1.2E-7 T 28-03-2018 MKLM6_RS06255 86c5080dd899e2d297f30ef1831e0016 1086 Gene3D G3DSA:3.30.2090.10 758 846 1.3E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS06255 86c5080dd899e2d297f30ef1831e0016 1086 SUPERFAMILY SSF82866 842 1077 3.4E-36 T 28-03-2018 MKLM6_RS06255 86c5080dd899e2d297f30ef1831e0016 1086 SUPERFAMILY SSF82714 760 843 9.29E-12 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS00005 c757655f7c8e60ea7b09c859981f4e83 438 Gene3D G3DSA:3.40.50.300 100 267 3.1E-22 T 28-03-2018 MKLM6_RS00005 c757655f7c8e60ea7b09c859981f4e83 438 ProSitePatterns PS01008 DnaA protein signature. 396 415 - T 28-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MKLM6_RS00005 c757655f7c8e60ea7b09c859981f4e83 438 Gene3D G3DSA:1.10.8.60 269 340 1.4E-26 T 28-03-2018 MKLM6_RS00005 c757655f7c8e60ea7b09c859981f4e83 438 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 2 437 31.842 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MKLM6_RS00005 c757655f7c8e60ea7b09c859981f4e83 438 Gene3D G3DSA:1.10.1750.10 341 437 2.4E-33 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 MKLM6_RS00005 c757655f7c8e60ea7b09c859981f4e83 438 SUPERFAMILY SSF48295 335 437 2.49E-35 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 MKLM6_RS00005 c757655f7c8e60ea7b09c859981f4e83 438 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 347 415 1.1E-30 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 MKLM6_RS00005 c757655f7c8e60ea7b09c859981f4e83 438 Pfam PF11638 DnaA N-terminal domain 4 63 2.0E-16 T 28-03-2018 IPR024633 DnaA N-terminal domain MKLM6_RS00005 c757655f7c8e60ea7b09c859981f4e83 438 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 5 436 3.0E-176 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MKLM6_RS00005 c757655f7c8e60ea7b09c859981f4e83 438 SMART SM00760 346 415 1.2E-40 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 MKLM6_RS00005 c757655f7c8e60ea7b09c859981f4e83 438 SUPERFAMILY SSF52540 104 315 2.2E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS00005 c757655f7c8e60ea7b09c859981f4e83 438 SMART SM00382 135 266 1.5E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS00005 c757655f7c8e60ea7b09c859981f4e83 438 Pfam PF00308 Bacterial dnaA protein 103 320 4.5E-94 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA MKLM6_RS00005 c757655f7c8e60ea7b09c859981f4e83 438 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 200 214 3.5E-51 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MKLM6_RS00005 c757655f7c8e60ea7b09c859981f4e83 438 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 396 415 3.5E-51 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MKLM6_RS00005 c757655f7c8e60ea7b09c859981f4e83 438 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 234 261 3.5E-51 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MKLM6_RS00005 c757655f7c8e60ea7b09c859981f4e83 438 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 168 182 3.5E-51 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MKLM6_RS00005 c757655f7c8e60ea7b09c859981f4e83 438 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 136 156 3.5E-51 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MKLM6_RS10190 d46d5401c278ee5ecc7655c2f743c5ed 229 SUPERFAMILY SSF53067 112 217 1.68E-18 T 28-03-2018 MKLM6_RS10190 d46d5401c278ee5ecc7655c2f743c5ed 229 Gene3D G3DSA:3.30.420.40 1 138 3.8E-35 T 28-03-2018 MKLM6_RS10190 d46d5401c278ee5ecc7655c2f743c5ed 229 SUPERFAMILY SSF53067 3 100 4.1E-27 T 28-03-2018 MKLM6_RS10190 d46d5401c278ee5ecc7655c2f743c5ed 229 Gene3D G3DSA:3.30.420.40 149 229 0.0039 T 28-03-2018 MKLM6_RS10190 d46d5401c278ee5ecc7655c2f743c5ed 229 Pfam PF00814 Glycoprotease family 29 146 8.2E-26 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MKLM6_RS10190 d46d5401c278ee5ecc7655c2f743c5ed 229 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 219 4.0E-55 T 28-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 MKLM6_RS09190 0df08936bae010580e96fbbdb83c0e0e 292 Pfam PF03411 Penicillin-insensitive murein endopeptidase 51 289 2.0E-97 T 28-03-2018 IPR005073 Peptidase M74, penicillin-insensitive murein endopeptidase GO:0004252|GO:0006508|GO:0030288 MKLM6_RS09190 0df08936bae010580e96fbbdb83c0e0e 292 Gene3D G3DSA:3.30.1380.10 33 292 4.0E-95 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MKLM6_RS09190 0df08936bae010580e96fbbdb83c0e0e 292 SUPERFAMILY SSF55166 47 291 1.02E-89 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MKLM6_RS09190 0df08936bae010580e96fbbdb83c0e0e 292 PIRSF PIRSF018455 11 292 2.9E-100 T 28-03-2018 IPR005073 Peptidase M74, penicillin-insensitive murein endopeptidase GO:0004252|GO:0006508|GO:0030288 MKLM6_RS05610 de401374938915855f4929742a8e428f 585 SUPERFAMILY SSF55874 410 574 1.15E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS05610 de401374938915855f4929742a8e428f 585 SMART SM00388 352 420 1.6E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS05610 de401374938915855f4929742a8e428f 585 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 472 575 4.7E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS05610 de401374938915855f4929742a8e428f 585 SUPERFAMILY SSF47384 339 419 1.02E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS05610 de401374938915855f4929742a8e428f 585 SUPERFAMILY SSF158472 293 334 7.98E-5 T 28-03-2018 MKLM6_RS05610 de401374938915855f4929742a8e428f 585 Gene3D G3DSA:1.10.287.130 343 416 1.0E-15 T 28-03-2018 MKLM6_RS05610 de401374938915855f4929742a8e428f 585 PRINTS PR00344 Bacterial sensor protein C-terminal signature 503 517 9.0E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS05610 de401374938915855f4929742a8e428f 585 PRINTS PR00344 Bacterial sensor protein C-terminal signature 536 554 9.0E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS05610 de401374938915855f4929742a8e428f 585 PRINTS PR00344 Bacterial sensor protein C-terminal signature 560 573 9.0E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS05610 de401374938915855f4929742a8e428f 585 Gene3D G3DSA:3.30.565.10 424 584 1.9E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS05610 de401374938915855f4929742a8e428f 585 SMART SM00387 466 576 3.3E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS05610 de401374938915855f4929742a8e428f 585 Pfam PF00512 His Kinase A (phospho-acceptor) domain 353 418 2.5E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS05610 de401374938915855f4929742a8e428f 585 Pfam PF00672 HAMP domain 293 338 1.6E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS15385 de939a9239dac402b59bcf9260821f09 555 Gene3D G3DSA:2.40.170.20 31 394 3.0E-4 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS15385 de939a9239dac402b59bcf9260821f09 555 Gene3D G3DSA:2.40.170.20 429 555 8.2E-4 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS15385 de939a9239dac402b59bcf9260821f09 555 TIGRFAM TIGR03016 pepcterm_hypo_1: uncharacterized protein, PEP-CTERM system associated 37 303 2.1E-40 T 28-03-2018 IPR017467 Conserved hypothetical protein CHP03016, PEP-CTERM MKLM6_RS07130 5b561e3e29415be285945275cd3665e2 615 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 123 600 7.3E-141 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 MKLM6_RS07130 5b561e3e29415be285945275cd3665e2 615 Pfam PF07549 SecD/SecF GG Motif 115 140 3.8E-7 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site MKLM6_RS07130 5b561e3e29415be285945275cd3665e2 615 Pfam PF02355 Protein export membrane protein 433 593 1.8E-18 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial MKLM6_RS07130 5b561e3e29415be285945275cd3665e2 615 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 3 615 48.157 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 MKLM6_RS07130 5b561e3e29415be285945275cd3665e2 615 Gene3D G3DSA:1.20.1640.10 373 604 1.4E-30 T 28-03-2018 MKLM6_RS07130 5b561e3e29415be285945275cd3665e2 615 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 344 593 1.5E-74 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MKLM6_RS07130 5b561e3e29415be285945275cd3665e2 615 SUPERFAMILY SSF82866 410 605 1.07E-41 T 28-03-2018 MKLM6_RS07130 5b561e3e29415be285945275cd3665e2 615 Pfam PF13721 SecD export protein N-terminal TM region 3 103 2.1E-29 T 28-03-2018 IPR027398 SecD export protein N-terminal TM domain MKLM6_RS15840 16e63b0bcfa16ed1dc0f1e7d358ede26 429 Gene3D G3DSA:3.90.1150.10 2 174 9.4E-34 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS15840 16e63b0bcfa16ed1dc0f1e7d358ede26 429 Gene3D G3DSA:3.40.640.10 175 308 7.9E-41 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS15840 16e63b0bcfa16ed1dc0f1e7d358ede26 429 SUPERFAMILY SSF53383 6 401 3.31E-96 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS15840 16e63b0bcfa16ed1dc0f1e7d358ede26 429 Pfam PF00202 Aminotransferase class-III 38 338 6.4E-55 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MKLM6_RS20470 8dcebe0d43f2d57a5940505f36a79099 158 Hamap MF_00821 Protein-export protein SecB [secB]. 1 146 33.258 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MKLM6_RS20470 8dcebe0d43f2d57a5940505f36a79099 158 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 9 141 1.0E-50 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MKLM6_RS20470 8dcebe0d43f2d57a5940505f36a79099 158 Pfam PF02556 Preprotein translocase subunit SecB 8 144 7.9E-55 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MKLM6_RS20470 8dcebe0d43f2d57a5940505f36a79099 158 SUPERFAMILY SSF54611 11 150 1.02E-50 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MKLM6_RS20470 8dcebe0d43f2d57a5940505f36a79099 158 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 14 31 2.3E-37 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MKLM6_RS20470 8dcebe0d43f2d57a5940505f36a79099 158 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 98 120 2.3E-37 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MKLM6_RS20470 8dcebe0d43f2d57a5940505f36a79099 158 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 124 142 2.3E-37 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MKLM6_RS20470 8dcebe0d43f2d57a5940505f36a79099 158 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 74 94 2.3E-37 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MKLM6_RS20470 8dcebe0d43f2d57a5940505f36a79099 158 Gene3D G3DSA:3.10.420.10 2 154 7.8E-53 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MKLM6_RS07095 f3c01457874b0561e5a65d79ae39d7ea 463 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 431 2.1E-24 T 28-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like MKLM6_RS07095 f3c01457874b0561e5a65d79ae39d7ea 463 Hamap MF_00195 GTPase Der [der]. 2 434 37.987 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 MKLM6_RS07095 f3c01457874b0561e5a65d79ae39d7ea 463 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 27 45 3.1E-9 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS07095 f3c01457874b0561e5a65d79ae39d7ea 463 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 72 90 3.1E-9 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS07095 f3c01457874b0561e5a65d79ae39d7ea 463 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 3.1E-9 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS07095 f3c01457874b0561e5a65d79ae39d7ea 463 Gene3D G3DSA:1.20.120.430 243 366 2.9E-14 T 28-03-2018 MKLM6_RS07095 f3c01457874b0561e5a65d79ae39d7ea 463 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 431 1.7E-171 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 MKLM6_RS07095 f3c01457874b0561e5a65d79ae39d7ea 463 Gene3D G3DSA:1.20.120.430 3 69 2.7E-14 T 28-03-2018 MKLM6_RS07095 f3c01457874b0561e5a65d79ae39d7ea 463 SUPERFAMILY SSF52540 4 169 5.84E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS07095 f3c01457874b0561e5a65d79ae39d7ea 463 Pfam PF01926 50S ribosome-binding GTPase 178 295 3.2E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS07095 f3c01457874b0561e5a65d79ae39d7ea 463 Pfam PF01926 50S ribosome-binding GTPase 5 119 4.5E-28 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS07095 f3c01457874b0561e5a65d79ae39d7ea 463 Gene3D G3DSA:3.30.300.20 367 432 3.8E-24 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta MKLM6_RS07095 f3c01457874b0561e5a65d79ae39d7ea 463 Gene3D G3DSA:1.20.120.430 70 242 3.2E-47 T 28-03-2018 MKLM6_RS07095 f3c01457874b0561e5a65d79ae39d7ea 463 PIRSF PIRSF006485 1 439 1.3E-172 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 MKLM6_RS07095 f3c01457874b0561e5a65d79ae39d7ea 463 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 176 341 2.9E-26 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MKLM6_RS07095 f3c01457874b0561e5a65d79ae39d7ea 463 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 156 2.6E-22 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MKLM6_RS07095 f3c01457874b0561e5a65d79ae39d7ea 463 SUPERFAMILY SSF52540 137 437 2.42E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS06370 453df735ff051d7262f0cebb69c4dd8e 363 SUPERFAMILY SSF48576 24 346 3.74E-61 T 28-03-2018 IPR008949 Isoprenoid synthase domain MKLM6_RS06370 453df735ff051d7262f0cebb69c4dd8e 363 Gene3D G3DSA:1.10.600.10 10 334 6.7E-71 T 28-03-2018 IPR008949 Isoprenoid synthase domain MKLM6_RS06370 453df735ff051d7262f0cebb69c4dd8e 363 Pfam PF00494 Squalene/phytoene synthase 29 317 1.9E-51 T 28-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 MKLM6_RS21835 7f8219031fd025672653a58a4aac5dc4 298 Gene3D G3DSA:3.30.70.20 50 97 3.8E-8 T 28-03-2018 MKLM6_RS21835 7f8219031fd025672653a58a4aac5dc4 298 SUPERFAMILY SSF54862 24 108 1.11E-11 T 28-03-2018 MKLM6_RS21835 7f8219031fd025672653a58a4aac5dc4 298 PIRSF PIRSF000371 1 294 2.9E-75 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 MKLM6_RS21835 7f8219031fd025672653a58a4aac5dc4 298 ProSitePatterns PS01087 Radical activating enzymes signature. 18 39 - T 28-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 MKLM6_RS21835 7f8219031fd025672653a58a4aac5dc4 298 TIGRFAM TIGR02494 PFLE_PFLC: glycyl-radical enzyme activating protein 7 290 4.4E-77 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 MKLM6_RS21835 7f8219031fd025672653a58a4aac5dc4 298 Gene3D G3DSA:3.30.70.20 98 136 0.0021 T 28-03-2018 MKLM6_RS21835 7f8219031fd025672653a58a4aac5dc4 298 Pfam PF13353 4Fe-4S single cluster domain 17 169 1.1E-7 T 28-03-2018 MKLM6_RS21835 7f8219031fd025672653a58a4aac5dc4 298 Gene3D G3DSA:3.80.30.10 137 297 8.2E-28 T 28-03-2018 MKLM6_RS21835 7f8219031fd025672653a58a4aac5dc4 298 Pfam PF04055 Radical SAM superfamily 25 237 5.0E-21 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS21835 7f8219031fd025672653a58a4aac5dc4 298 SUPERFAMILY SSF102114 88 278 4.12E-17 T 28-03-2018 MKLM6_RS22615 2d9ae8e3cdc6452f7a51216c754adbc2 900 Gene3D G3DSA:3.40.190.10 509 606 0.053 T 28-03-2018 MKLM6_RS22615 2d9ae8e3cdc6452f7a51216c754adbc2 900 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 615 691 1.1E-24 T 28-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 MKLM6_RS22615 2d9ae8e3cdc6452f7a51216c754adbc2 900 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 269 306 1.8E-5 T 28-03-2018 IPR006530 YD repeat MKLM6_RS22615 2d9ae8e3cdc6452f7a51216c754adbc2 900 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 353 381 1.7E-4 T 28-03-2018 IPR006530 YD repeat MKLM6_RS22615 2d9ae8e3cdc6452f7a51216c754adbc2 900 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 214 244 1.9E-4 T 28-03-2018 IPR006530 YD repeat MKLM6_RS22615 2d9ae8e3cdc6452f7a51216c754adbc2 900 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 332 370 1.1E-5 T 28-03-2018 IPR006530 YD repeat MKLM6_RS22615 2d9ae8e3cdc6452f7a51216c754adbc2 900 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 143 172 0.0011 T 28-03-2018 IPR006530 YD repeat MKLM6_RS22615 2d9ae8e3cdc6452f7a51216c754adbc2 900 Pfam PF05593 RHS Repeat 311 346 4.1E-7 T 28-03-2018 IPR031325 RHS repeat MKLM6_RS22615 2d9ae8e3cdc6452f7a51216c754adbc2 900 Pfam PF05593 RHS Repeat 353 386 5.3E-6 T 28-03-2018 IPR031325 RHS repeat MKLM6_RS17155 898a1e5b94af989a921f511b54fe11e9 355 Pfam PF13847 Methyltransferase domain 175 304 2.2E-15 T 28-03-2018 IPR025714 Methyltransferase domain MKLM6_RS17155 898a1e5b94af989a921f511b54fe11e9 355 SUPERFAMILY SSF53335 121 341 1.05E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS17155 898a1e5b94af989a921f511b54fe11e9 355 Gene3D G3DSA:1.10.10.10 29 79 2.1E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS17155 898a1e5b94af989a921f511b54fe11e9 355 Gene3D G3DSA:3.40.50.150 80 355 4.8E-23 T 28-03-2018 MKLM6_RS17155 898a1e5b94af989a921f511b54fe11e9 355 SUPERFAMILY SSF46785 31 98 9.66E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS00940 1370a276cbf1df0e1f0c667e666c200f 312 SUPERFAMILY SSF51391 119 310 7.59E-38 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MKLM6_RS00940 1370a276cbf1df0e1f0c667e666c200f 312 Gene3D G3DSA:3.20.20.70 119 312 3.3E-23 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS00940 1370a276cbf1df0e1f0c667e666c200f 312 Pfam PF02581 Thiamine monophosphate synthase 137 309 2.2E-34 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MKLM6_RS00940 1370a276cbf1df0e1f0c667e666c200f 312 PRINTS PR00502 NUDIX hydrolase family signature 51 66 6.5E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MKLM6_RS00940 1370a276cbf1df0e1f0c667e666c200f 312 PRINTS PR00502 NUDIX hydrolase family signature 37 51 6.5E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MKLM6_RS00940 1370a276cbf1df0e1f0c667e666c200f 312 Gene3D G3DSA:3.90.79.10 6 118 4.4E-29 T 28-03-2018 MKLM6_RS00940 1370a276cbf1df0e1f0c667e666c200f 312 SUPERFAMILY SSF55811 7 130 2.03E-37 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MKLM6_RS00940 1370a276cbf1df0e1f0c667e666c200f 312 TIGRFAM TIGR00586 mutt: mutator mutT protein 8 129 8.7E-32 T 28-03-2018 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 MKLM6_RS00940 1370a276cbf1df0e1f0c667e666c200f 312 ProSitePatterns PS00893 Nudix box signature. 42 63 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MKLM6_RS00940 1370a276cbf1df0e1f0c667e666c200f 312 Pfam PF14815 NUDIX domain 11 128 6.2E-19 T 28-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MKLM6_RS09570 f5086351a411d09790d3ee55c84830c1 295 Pfam PF00691 OmpA family 184 279 7.1E-24 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS09570 f5086351a411d09790d3ee55c84830c1 295 Pfam PF14346 Domain of unknown function (DUF4398) 15 114 1.9E-14 T 28-03-2018 IPR025511 Domain of unknown function DUF4398 MKLM6_RS09570 f5086351a411d09790d3ee55c84830c1 295 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 248 267 1.0E-7 T 28-03-2018 MKLM6_RS09570 f5086351a411d09790d3ee55c84830c1 295 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 268 288 1.0E-7 T 28-03-2018 MKLM6_RS09570 f5086351a411d09790d3ee55c84830c1 295 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 230 247 1.0E-7 T 28-03-2018 MKLM6_RS09570 f5086351a411d09790d3ee55c84830c1 295 SUPERFAMILY SSF103088 174 285 1.7E-38 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS09570 f5086351a411d09790d3ee55c84830c1 295 PRINTS PR01021 OMPA domain signature 230 246 2.9E-12 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MKLM6_RS09570 f5086351a411d09790d3ee55c84830c1 295 PRINTS PR01021 OMPA domain signature 215 230 2.9E-12 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MKLM6_RS09570 f5086351a411d09790d3ee55c84830c1 295 PRINTS PR01021 OMPA domain signature 185 207 2.9E-12 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MKLM6_RS09570 f5086351a411d09790d3ee55c84830c1 295 Gene3D G3DSA:3.30.1330.60 153 295 5.7E-43 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS21235 a79244c7e2ce713cf6c4f2ea678b03e6 224 Gene3D G3DSA:3.30.1150.10 128 222 4.3E-8 T 28-03-2018 MKLM6_RS21235 a79244c7e2ce713cf6c4f2ea678b03e6 224 Pfam PF13103 TonB C terminal 134 218 3.9E-7 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 MKLM6_RS21235 a79244c7e2ce713cf6c4f2ea678b03e6 224 SUPERFAMILY SSF74653 78 91 7.32E-14 T 28-03-2018 MKLM6_RS21235 a79244c7e2ce713cf6c4f2ea678b03e6 224 SUPERFAMILY SSF74653 122 220 7.32E-14 T 28-03-2018 MKLM6_RS10455 a79244c7e2ce713cf6c4f2ea678b03e6 224 Gene3D G3DSA:3.30.1150.10 128 222 4.3E-8 T 28-03-2018 MKLM6_RS10455 a79244c7e2ce713cf6c4f2ea678b03e6 224 Pfam PF13103 TonB C terminal 134 218 3.9E-7 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 MKLM6_RS10455 a79244c7e2ce713cf6c4f2ea678b03e6 224 SUPERFAMILY SSF74653 78 91 7.32E-14 T 28-03-2018 MKLM6_RS10455 a79244c7e2ce713cf6c4f2ea678b03e6 224 SUPERFAMILY SSF74653 122 220 7.32E-14 T 28-03-2018 MKLM6_RS00580 ff38caa39a6f7909a44374854ae4a751 202 SUPERFAMILY SSF142695 4 173 5.49E-63 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 MKLM6_RS00580 ff38caa39a6f7909a44374854ae4a751 202 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 3 198 38.04 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 MKLM6_RS00580 ff38caa39a6f7909a44374854ae4a751 202 Pfam PF00925 GTP cyclohydrolase II 9 171 2.1E-69 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 MKLM6_RS00580 ff38caa39a6f7909a44374854ae4a751 202 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 8 196 7.1E-74 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 MKLM6_RS21590 5fb18961fd7dbb0324184f8ab6700d7b 760 Gene3D G3DSA:2.130.10.10 85 414 6.7E-12 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MKLM6_RS21590 5fb18961fd7dbb0324184f8ab6700d7b 760 SUPERFAMILY SSF161098 565 746 5.49E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MKLM6_RS21590 5fb18961fd7dbb0324184f8ab6700d7b 760 SUPERFAMILY SSF50978 239 421 1.65E-11 T 28-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 MKLM6_RS21590 5fb18961fd7dbb0324184f8ab6700d7b 760 SUPERFAMILY SSF50978 104 172 1.65E-11 T 28-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 MKLM6_RS21590 5fb18961fd7dbb0324184f8ab6700d7b 760 SUPERFAMILY SSF161098 456 547 9.03E-6 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MKLM6_RS21590 5fb18961fd7dbb0324184f8ab6700d7b 760 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 480 754 1.4E-10 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MKLM6_RS21590 5fb18961fd7dbb0324184f8ab6700d7b 760 Gene3D G3DSA:1.10.3720.10 451 556 3.7E-5 T 28-03-2018 MKLM6_RS21590 5fb18961fd7dbb0324184f8ab6700d7b 760 Gene3D G3DSA:1.10.3720.10 562 747 1.5E-27 T 28-03-2018 MKLM6_RS04715 5176fb8cb62aef51ac1cdf4d4ec53be5 416 Gene3D G3DSA:3.40.50.300 1 403 5.4E-17 T 28-03-2018 MKLM6_RS04715 5176fb8cb62aef51ac1cdf4d4ec53be5 416 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 49 362 2.0E-26 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MKLM6_RS04715 5176fb8cb62aef51ac1cdf4d4ec53be5 416 SUPERFAMILY SSF52540 49 363 2.07E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS02540 e10df44ab5783204e66fa60ea3e5425e 375 SUPERFAMILY SSF52317 36 241 9.47E-32 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS02540 e10df44ab5783204e66fa60ea3e5425e 375 SUPERFAMILY SSF46689 260 309 3.08E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS02540 e10df44ab5783204e66fa60ea3e5425e 375 Gene3D G3DSA:1.10.10.60 315 374 1.4E-15 T 28-03-2018 MKLM6_RS02540 e10df44ab5783204e66fa60ea3e5425e 375 Pfam PF12833 Helix-turn-helix domain 283 361 1.2E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MKLM6_RS02540 e10df44ab5783204e66fa60ea3e5425e 375 SUPERFAMILY SSF46689 312 364 3.36E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS02540 e10df44ab5783204e66fa60ea3e5425e 375 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 313 355 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MKLM6_RS02540 e10df44ab5783204e66fa60ea3e5425e 375 Gene3D G3DSA:3.40.50.880 33 254 1.2E-36 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS02540 e10df44ab5783204e66fa60ea3e5425e 375 Gene3D G3DSA:1.10.10.60 255 314 5.0E-15 T 28-03-2018 MKLM6_RS02540 e10df44ab5783204e66fa60ea3e5425e 375 SMART SM00342 276 359 1.6E-27 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MKLM6_RS09140 11e6096361f8f3644ab64219ce1f9c4b 421 SUPERFAMILY SSF111369 79 317 5.49E-53 T 28-03-2018 MKLM6_RS09140 11e6096361f8f3644ab64219ce1f9c4b 421 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 65 393 1.2E-68 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MKLM6_RS09140 11e6096361f8f3644ab64219ce1f9c4b 421 Gene3D G3DSA:1.10.287.470 147 195 7.1E-6 T 28-03-2018 MKLM6_RS09140 11e6096361f8f3644ab64219ce1f9c4b 421 Pfam PF13437 HlyD family secretion protein 201 303 6.7E-10 T 28-03-2018 MKLM6_RS09140 11e6096361f8f3644ab64219ce1f9c4b 421 Gene3D G3DSA:2.40.50.100 89 146 3.9E-18 T 28-03-2018 MKLM6_RS09140 11e6096361f8f3644ab64219ce1f9c4b 421 Pfam PF13533 Biotin-lipoyl like 90 138 1.6E-15 T 28-03-2018 MKLM6_RS09140 11e6096361f8f3644ab64219ce1f9c4b 421 Gene3D G3DSA:2.40.50.100 196 404 9.4E-6 T 28-03-2018 MKLM6_RS05005 dd1ae08238a16d3be133b6c37f09dd96 422 Pfam PF12838 4Fe-4S dicluster domain 33 95 2.6E-10 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MKLM6_RS05005 dd1ae08238a16d3be133b6c37f09dd96 422 Pfam PF02754 Cysteine-rich domain 194 274 2.0E-12 T 28-03-2018 IPR004017 Cysteine-rich domain MKLM6_RS05005 dd1ae08238a16d3be133b6c37f09dd96 422 Pfam PF02754 Cysteine-rich domain 317 400 2.7E-7 T 28-03-2018 IPR004017 Cysteine-rich domain MKLM6_RS05005 dd1ae08238a16d3be133b6c37f09dd96 422 SUPERFAMILY SSF54862 26 116 7.11E-17 T 28-03-2018 MKLM6_RS05005 dd1ae08238a16d3be133b6c37f09dd96 422 PIRSF PIRSF000139 19 422 2.9E-90 T 28-03-2018 MKLM6_RS05005 dd1ae08238a16d3be133b6c37f09dd96 422 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 33 44 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MKLM6_RS05005 dd1ae08238a16d3be133b6c37f09dd96 422 Gene3D G3DSA:1.10.1060.10 16 116 2.0E-15 T 28-03-2018 MKLM6_RS05005 dd1ae08238a16d3be133b6c37f09dd96 422 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MKLM6_RS07310 916b04a5d8a66735e4d1358d44e69c68 428 SUPERFAMILY SSF54534 283 381 8.5E-30 T 28-03-2018 MKLM6_RS07310 916b04a5d8a66735e4d1358d44e69c68 428 Pfam PF13616 PPIC-type PPIASE domain 282 380 1.8E-27 T 28-03-2018 MKLM6_RS07310 916b04a5d8a66735e4d1358d44e69c68 428 Pfam PF00639 PPIC-type PPIASE domain 178 270 8.2E-21 T 28-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 MKLM6_RS07310 916b04a5d8a66735e4d1358d44e69c68 428 SUPERFAMILY SSF54534 173 274 1.24E-25 T 28-03-2018 MKLM6_RS07310 916b04a5d8a66735e4d1358d44e69c68 428 Gene3D G3DSA:1.10.4030.10 21 148 1.5E-21 T 28-03-2018 MKLM6_RS07310 916b04a5d8a66735e4d1358d44e69c68 428 Gene3D G3DSA:3.10.50.40 279 405 1.5E-31 T 28-03-2018 MKLM6_RS07310 916b04a5d8a66735e4d1358d44e69c68 428 Pfam PF09312 SurA N-terminal domain 25 142 9.2E-39 T 28-03-2018 IPR015391 SurA N-terminal MKLM6_RS07310 916b04a5d8a66735e4d1358d44e69c68 428 Gene3D G3DSA:3.10.50.40 167 278 9.0E-25 T 28-03-2018 MKLM6_RS07310 916b04a5d8a66735e4d1358d44e69c68 428 Hamap MF_01183 Chaperone SurA [surA]. 6 426 33.253 T 28-03-2018 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0042710|GO:0043165|GO:0050821|GO:0051082|GO:0051085|GO:0060274 MKLM6_RS07310 916b04a5d8a66735e4d1358d44e69c68 428 SUPERFAMILY SSF109998 25 201 4.05E-43 T 28-03-2018 IPR027304 Trigger factor/SurA domain MKLM6_RS11190 a67ff69799ebe100fc73dafb9a2816fe 308 Gene3D G3DSA:1.10.8.300 195 303 5.7E-30 T 28-03-2018 MKLM6_RS11190 a67ff69799ebe100fc73dafb9a2816fe 308 PIRSF PIRSF002849 1 308 6.7E-123 T 28-03-2018 MKLM6_RS11190 a67ff69799ebe100fc73dafb9a2816fe 308 SMART SM00382 31 172 3.1E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS11190 a67ff69799ebe100fc73dafb9a2816fe 308 Gene3D G3DSA:3.40.50.300 15 181 2.4E-26 T 28-03-2018 MKLM6_RS11190 a67ff69799ebe100fc73dafb9a2816fe 308 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 34 163 6.2E-60 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 MKLM6_RS11190 a67ff69799ebe100fc73dafb9a2816fe 308 SUPERFAMILY SSF52540 5 278 4.42E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS18010 60e12db0ac0564d397f6c2ab625a78d6 467 Pfam PF07196 Flagellin hook IN motif 128 191 3.5E-6 T 28-03-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 MKLM6_RS18010 60e12db0ac0564d397f6c2ab625a78d6 467 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 11 107 1.1E-21 T 28-03-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 MKLM6_RS18010 60e12db0ac0564d397f6c2ab625a78d6 467 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 228 454 1.6E-50 T 28-03-2018 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 MKLM6_RS18010 60e12db0ac0564d397f6c2ab625a78d6 467 Gene3D G3DSA:3.90.20.10 321 458 2.7E-4 T 28-03-2018 MKLM6_RS04975 c84fa16e535411241728624bead05d15 103 Gene3D G3DSA:3.30.70.20 16 81 2.0E-11 T 28-03-2018 MKLM6_RS04975 c84fa16e535411241728624bead05d15 103 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 80 91 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MKLM6_RS04975 c84fa16e535411241728624bead05d15 103 Pfam PF14697 4Fe-4S dicluster domain 23 96 3.9E-10 T 28-03-2018 MKLM6_RS04975 c84fa16e535411241728624bead05d15 103 SUPERFAMILY SSF54862 9 98 1.03E-15 T 28-03-2018 MKLM6_RS04975 c84fa16e535411241728624bead05d15 103 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 28 39 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MKLM6_RS04975 c84fa16e535411241728624bead05d15 103 Gene3D G3DSA:3.30.70.20 82 102 0.0017 T 28-03-2018 MKLM6_RS04975 c84fa16e535411241728624bead05d15 103 TIGRFAM TIGR02936 fdxN_nitrog: ferredoxin III, nif-specific 7 98 4.0E-35 T 28-03-2018 IPR014283 Ferredoxin III 4[4Fe-4S], nif-specific MKLM6_RS07530 401c15211fea1bea622e38a4028e9ab0 508 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 291 297 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MKLM6_RS07530 401c15211fea1bea622e38a4028e9ab0 508 SUPERFAMILY SSF53335 14 507 2.61E-141 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS07530 401c15211fea1bea622e38a4028e9ab0 508 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 288 300 5.8E-14 T 28-03-2018 MKLM6_RS07530 401c15211fea1bea622e38a4028e9ab0 508 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 213 227 5.8E-14 T 28-03-2018 MKLM6_RS07530 401c15211fea1bea622e38a4028e9ab0 508 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 189 205 5.8E-14 T 28-03-2018 MKLM6_RS07530 401c15211fea1bea622e38a4028e9ab0 508 Pfam PF12161 HsdM N-terminal domain 17 151 3.9E-28 T 28-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain MKLM6_RS07530 401c15211fea1bea622e38a4028e9ab0 508 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 14 486 2.3E-91 T 28-03-2018 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 MKLM6_RS07530 401c15211fea1bea622e38a4028e9ab0 508 Pfam PF02384 N-6 DNA Methylase 167 471 2.7E-108 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 MKLM6_RS07530 401c15211fea1bea622e38a4028e9ab0 508 Gene3D G3DSA:3.40.50.150 187 466 3.2E-69 T 28-03-2018 MKLM6_RS12430 ffe930b416e2ec36ebe4e95b9e0a62d6 354 Pfam PF01545 Cation efflux family 30 272 1.4E-36 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MKLM6_RS12430 ffe930b416e2ec36ebe4e95b9e0a62d6 354 Gene3D G3DSA:1.20.1510.10 22 272 2.1E-51 T 28-03-2018 MKLM6_RS12430 ffe930b416e2ec36ebe4e95b9e0a62d6 354 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 23 344 2.2E-58 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MKLM6_RS12430 ffe930b416e2ec36ebe4e95b9e0a62d6 354 SUPERFAMILY SSF161111 205 273 6.28E-47 T 28-03-2018 MKLM6_RS12430 ffe930b416e2ec36ebe4e95b9e0a62d6 354 SUPERFAMILY SSF161111 20 152 6.28E-47 T 28-03-2018 MKLM6_RS04490 87270cea34682459d1f7618180e1cc04 277 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 8 270 51.751 T 28-03-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MKLM6_RS04490 87270cea34682459d1f7618180e1cc04 277 Pfam PF00793 DAHP synthetase I family 7 265 7.1E-69 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MKLM6_RS04490 87270cea34682459d1f7618180e1cc04 277 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 13 268 1.3E-123 T 28-03-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MKLM6_RS04490 87270cea34682459d1f7618180e1cc04 277 SUPERFAMILY SSF51569 2 270 6.59E-107 T 28-03-2018 MKLM6_RS04490 87270cea34682459d1f7618180e1cc04 277 Gene3D G3DSA:3.20.20.70 11 273 2.2E-76 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS19535 69730b725bbe135d000b39d700fd3a80 285 Gene3D G3DSA:3.40.630.30 4 202 2.3E-8 T 28-03-2018 MKLM6_RS19535 69730b725bbe135d000b39d700fd3a80 285 SUPERFAMILY SSF55729 5 94 1.28E-7 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 Gene3D G3DSA:3.30.565.10 486 654 1.7E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 SUPERFAMILY SSF158472 183 232 1.24E-5 T 28-03-2018 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 SUPERFAMILY SSF47384 403 483 9.81E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 SMART SM00073 977 1073 0.0039 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 SUPERFAMILY SSF52172 667 795 2.85E-34 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 Pfam PF00512 His Kinase A (phospho-acceptor) domain 418 482 3.7E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 SMART SM00387 529 646 5.7E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 SUPERFAMILY SSF47226 920 933 2.88E-15 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 SUPERFAMILY SSF47226 966 1064 2.88E-15 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 SMART SM00304 183 236 8.9E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 SMART SM00388 417 482 2.5E-23 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 SUPERFAMILY SSF55874 471 642 3.8E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 Pfam PF12860 PAS fold 288 401 2.4E-28 T 28-03-2018 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 Gene3D G3DSA:1.20.120.160 961 1160 1.6E-12 T 28-03-2018 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 Gene3D G3DSA:1.10.287.130 413 478 6.2E-19 T 28-03-2018 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 Pfam PF01627 Hpt domain 988 1067 3.0E-6 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 Gene3D G3DSA:3.30.450.20 292 412 5.9E-12 T 28-03-2018 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 529 644 5.2E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 Pfam PF17152 Periplasmic sensor domain 42 145 1.2E-15 T 28-03-2018 IPR033417 Periplasmic sensor domain CHASE8 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 PRINTS PR00344 Bacterial sensor protein C-terminal signature 588 598 1.9E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 PRINTS PR00344 Bacterial sensor protein C-terminal signature 605 623 1.9E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 PRINTS PR00344 Bacterial sensor protein C-terminal signature 570 584 1.9E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 PRINTS PR00344 Bacterial sensor protein C-terminal signature 630 643 1.9E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 SUPERFAMILY SSF55785 272 395 3.14E-6 T 28-03-2018 IPR000014 PAS domain MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 Gene3D G3DSA:3.90.20.10 171 291 0.028 T 28-03-2018 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 Gene3D G3DSA:3.40.50.2300 811 960 9.5E-42 T 28-03-2018 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 SUPERFAMILY SSF52172 816 948 2.85E-38 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 Pfam PF00072 Response regulator receiver domain 821 937 9.3E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 Pfam PF00072 Response regulator receiver domain 670 785 5.1E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 SMART SM00448 818 937 2.7E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 SMART SM00448 668 785 1.1E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS12190 76c42d280ce52a3e4a6fdd7fdd2ddbb5 1160 Gene3D G3DSA:3.40.50.2300 665 808 3.6E-35 T 28-03-2018 MKLM6_RS22495 ec5db9e1038f505febe2e0fd9407717c 315 Pfam PF13728 F plasmid transfer operon protein 33 260 5.8E-74 T 28-03-2018 MKLM6_RS22495 ec5db9e1038f505febe2e0fd9407717c 315 SUPERFAMILY SSF52833 155 259 9.19E-11 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS22495 ec5db9e1038f505febe2e0fd9407717c 315 TIGRFAM TIGR02740 TraF-like: TraF-like protein 15 270 9.5E-86 T 28-03-2018 IPR014111 Type IV conjugative transfer system protein TraF MKLM6_RS22495 ec5db9e1038f505febe2e0fd9407717c 315 Gene3D G3DSA:3.40.30.10 140 266 2.8E-10 T 28-03-2018 MKLM6_RS11780 3bb33cf01498de57d816c10c76c2927e 151 Gene3D G3DSA:3.30.450.20 14 143 6.8E-28 T 28-03-2018 MKLM6_RS11780 3bb33cf01498de57d816c10c76c2927e 151 SUPERFAMILY SSF55785 26 131 1.92E-27 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11780 3bb33cf01498de57d816c10c76c2927e 151 SMART SM00091 14 83 2.9E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11780 3bb33cf01498de57d816c10c76c2927e 151 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 35 137 1.1E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11780 3bb33cf01498de57d816c10c76c2927e 151 SMART SM00086 89 131 7.5E-11 T 28-03-2018 IPR001610 PAC motif MKLM6_RS11780 3bb33cf01498de57d816c10c76c2927e 151 Pfam PF13426 PAS domain 26 130 2.6E-22 T 28-03-2018 IPR000014 PAS domain MKLM6_RS20480 a4c48eab09188e329da70c44bf733114 155 Gene3D G3DSA:2.10.260.10 4 46 6.3E-4 T 28-03-2018 MKLM6_RS20480 a4c48eab09188e329da70c44bf733114 155 Gene3D G3DSA:2.10.260.10 86 135 7.7E-8 T 28-03-2018 MKLM6_RS20480 a4c48eab09188e329da70c44bf733114 155 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 131 1.0E-40 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 MKLM6_RS20480 a4c48eab09188e329da70c44bf733114 155 Pfam PF02381 MraZ protein, putative antitoxin-like 84 137 3.8E-18 T 28-03-2018 IPR020603 MraZ domain MKLM6_RS20480 a4c48eab09188e329da70c44bf733114 155 Pfam PF02381 MraZ protein, putative antitoxin-like 1 78 2.2E-13 T 28-03-2018 IPR020603 MraZ domain MKLM6_RS20480 a4c48eab09188e329da70c44bf733114 155 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 138 4.9E-43 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 MKLM6_RS20480 a4c48eab09188e329da70c44bf733114 155 SUPERFAMILY SSF89447 2 140 6.28E-43 T 28-03-2018 MKLM6_RS20480 a4c48eab09188e329da70c44bf733114 155 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 155 50.835 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 MKLM6_RS17270 9034b25a5c356054f9e5714ed8f51a65 163 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 7 142 5.9E-20 T 28-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MKLM6_RS17270 9034b25a5c356054f9e5714ed8f51a65 163 SUPERFAMILY SSF53163 5 147 7.32E-26 T 28-03-2018 IPR023430 Peptidase HybD-like domain MKLM6_RS17270 9034b25a5c356054f9e5714ed8f51a65 163 Gene3D G3DSA:3.40.50.1450 5 157 1.9E-24 T 28-03-2018 IPR023430 Peptidase HybD-like domain MKLM6_RS16770 eb5146c9213eaf275262403fe00da003 393 Gene3D G3DSA:1.10.3720.10 8 375 5.2E-35 T 28-03-2018 MKLM6_RS16770 eb5146c9213eaf275262403fe00da003 393 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 204 386 5.8E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MKLM6_RS16770 eb5146c9213eaf275262403fe00da003 393 SUPERFAMILY SSF161098 182 367 2.62E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MKLM6_RS02660 72efb2b49f6eea3536b5f1824a28fbca 103 SMART SM00278 59 78 13.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MKLM6_RS02660 72efb2b49f6eea3536b5f1824a28fbca 103 SMART SM00278 29 48 1.1 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MKLM6_RS02660 72efb2b49f6eea3536b5f1824a28fbca 103 Gene3D G3DSA:1.10.150.20 64 91 0.068 T 28-03-2018 MKLM6_RS02660 72efb2b49f6eea3536b5f1824a28fbca 103 Gene3D G3DSA:1.10.150.20 6 45 2.3E-11 T 28-03-2018 MKLM6_RS02660 72efb2b49f6eea3536b5f1824a28fbca 103 Pfam PF12836 Helix-hairpin-helix motif 16 79 2.2E-20 T 28-03-2018 MKLM6_RS02660 72efb2b49f6eea3536b5f1824a28fbca 103 Gene3D G3DSA:1.10.150.20 46 63 2.2E-4 T 28-03-2018 MKLM6_RS02660 72efb2b49f6eea3536b5f1824a28fbca 103 SUPERFAMILY SSF47781 17 86 1.11E-21 T 28-03-2018 IPR010994 RuvA domain 2-like MKLM6_RS02660 72efb2b49f6eea3536b5f1824a28fbca 103 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 20 81 6.6E-21 T 28-03-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain MKLM6_RS15875 e3a02fa7b1bcba4d77252b537c7d4825 99 SUPERFAMILY SSF81301 10 81 9.22E-11 T 28-03-2018 MKLM6_RS15875 e3a02fa7b1bcba4d77252b537c7d4825 99 Pfam PF01909 Nucleotidyltransferase domain 11 80 4.3E-6 T 28-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 MKLM6_RS15875 e3a02fa7b1bcba4d77252b537c7d4825 99 Gene3D G3DSA:3.30.460.10 1 97 4.8E-10 T 28-03-2018 MKLM6_RS14440 a44b1734a7aa6789d7dab809a1490c1e 221 SUPERFAMILY SSF46785 149 215 3.43E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS14440 a44b1734a7aa6789d7dab809a1490c1e 221 SMART SM00100 14 135 7.6E-22 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain MKLM6_RS14440 a44b1734a7aa6789d7dab809a1490c1e 221 SUPERFAMILY SSF51206 8 145 1.57E-34 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like MKLM6_RS14440 a44b1734a7aa6789d7dab809a1490c1e 221 Pfam PF00027 Cyclic nucleotide-binding domain 33 120 1.0E-19 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain MKLM6_RS14440 a44b1734a7aa6789d7dab809a1490c1e 221 SMART SM00419 165 215 3.2E-7 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MKLM6_RS14440 a44b1734a7aa6789d7dab809a1490c1e 221 Gene3D G3DSA:2.60.120.10 2 142 2.3E-35 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS14440 a44b1734a7aa6789d7dab809a1490c1e 221 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 82 99 - T 28-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site MKLM6_RS14440 a44b1734a7aa6789d7dab809a1490c1e 221 Gene3D G3DSA:1.10.10.10 143 218 1.8E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS14440 a44b1734a7aa6789d7dab809a1490c1e 221 PRINTS PR00103 cAMP-dependent protein kinase signature 92 103 6.4E-6 T 28-03-2018 MKLM6_RS14440 a44b1734a7aa6789d7dab809a1490c1e 221 PRINTS PR00103 cAMP-dependent protein kinase signature 50 64 6.4E-6 T 28-03-2018 MKLM6_RS14440 a44b1734a7aa6789d7dab809a1490c1e 221 PRINTS PR00103 cAMP-dependent protein kinase signature 35 49 6.4E-6 T 28-03-2018 MKLM6_RS14440 a44b1734a7aa6789d7dab809a1490c1e 221 PRINTS PR00103 cAMP-dependent protein kinase signature 80 89 6.4E-6 T 28-03-2018 MKLM6_RS14440 a44b1734a7aa6789d7dab809a1490c1e 221 Pfam PF13545 Crp-like helix-turn-helix domain 152 214 1.4E-9 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MKLM6_RS08875 cc9f45a6d2fb6368b7791fc1c2bdd24c 388 SUPERFAMILY SSF53383 4 363 8.78E-98 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS08875 cc9f45a6d2fb6368b7791fc1c2bdd24c 388 Pfam PF00266 Aminotransferase class-V 7 334 2.3E-33 T 28-03-2018 IPR000192 Aminotransferase class V domain MKLM6_RS08875 cc9f45a6d2fb6368b7791fc1c2bdd24c 388 PIRSF PIRSF000524 1 388 1.3E-128 T 28-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 MKLM6_RS08875 cc9f45a6d2fb6368b7791fc1c2bdd24c 388 Gene3D G3DSA:3.90.1150.10 271 388 3.5E-33 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS08875 cc9f45a6d2fb6368b7791fc1c2bdd24c 388 Gene3D G3DSA:3.40.640.10 13 270 2.9E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS07780 a6d85073283844b3e53b2951eba7bf4a 173 Pfam PF10688 Bacterial inner membrane protein 10 170 2.8E-33 T 28-03-2018 IPR019629 Uncharacterised protein family HI1736/YgjV MKLM6_RS06390 dc57811bb960fb8ef39f97873c465134 171 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 4 171 1.3E-63 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 MKLM6_RS06390 dc57811bb960fb8ef39f97873c465134 171 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 4 171 36.401 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 MKLM6_RS06390 dc57811bb960fb8ef39f97873c465134 171 Gene3D G3DSA:3.40.50.2020 1 171 1.9E-36 T 28-03-2018 MKLM6_RS06390 dc57811bb960fb8ef39f97873c465134 171 Pfam PF00156 Phosphoribosyl transferase domain 48 149 8.1E-13 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MKLM6_RS06390 dc57811bb960fb8ef39f97873c465134 171 SUPERFAMILY SSF53271 5 165 8.0E-49 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like MKLM6_RS10170 5115b32301ca321585d5aaf7c7188457 470 Gene3D G3DSA:3.40.50.300 262 464 3.4E-21 T 28-03-2018 MKLM6_RS10170 5115b32301ca321585d5aaf7c7188457 470 SMART SM00670 9 150 1.5E-10 T 28-03-2018 IPR002716 PIN domain MKLM6_RS10170 5115b32301ca321585d5aaf7c7188457 470 SUPERFAMILY SSF52540 257 449 4.56E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS10170 5115b32301ca321585d5aaf7c7188457 470 Gene3D G3DSA:3.40.50.1010 8 261 2.4E-43 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS10170 5115b32301ca321585d5aaf7c7188457 470 Pfam PF13638 PIN domain 11 163 3.2E-40 T 28-03-2018 IPR002716 PIN domain MKLM6_RS10170 5115b32301ca321585d5aaf7c7188457 470 SUPERFAMILY SSF88723 9 70 6.87E-12 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS10170 5115b32301ca321585d5aaf7c7188457 470 SUPERFAMILY SSF88723 113 164 6.87E-12 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS10170 5115b32301ca321585d5aaf7c7188457 470 Pfam PF02562 PhoH-like protein 258 457 2.4E-51 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 MKLM6_RS16060 0fafe9184bfce84870d9a1b298060056 337 SUPERFAMILY SSF51395 1 307 7.0E-56 T 28-03-2018 MKLM6_RS16060 0fafe9184bfce84870d9a1b298060056 337 Gene3D G3DSA:3.20.20.70 1 322 3.3E-35 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS16060 0fafe9184bfce84870d9a1b298060056 337 Pfam PF01180 Dihydroorotate dehydrogenase 87 291 1.3E-10 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 MKLM6_RS16060 0fafe9184bfce84870d9a1b298060056 337 PIRSF PIRSF000164 1 61 3.4E-4 T 28-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 MKLM6_RS16060 0fafe9184bfce84870d9a1b298060056 337 PIRSF PIRSF000164 87 308 1.6E-30 T 28-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 MKLM6_RS15755 bb148b558b95b69fbda3f155625fdb5c 416 Gene3D G3DSA:3.40.50.2000 222 381 4.1E-12 T 28-03-2018 MKLM6_RS15755 bb148b558b95b69fbda3f155625fdb5c 416 SUPERFAMILY SSF53756 82 408 2.33E-21 T 28-03-2018 MKLM6_RS15755 bb148b558b95b69fbda3f155625fdb5c 416 Gene3D G3DSA:3.40.50.2000 19 221 3.7E-9 T 28-03-2018 MKLM6_RS15755 bb148b558b95b69fbda3f155625fdb5c 416 Pfam PF13579 Glycosyl transferase 4-like domain 79 206 1.1E-9 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MKLM6_RS16775 dd8fff41136dcd5260d0080d0116c9d2 357 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 138 355 5.0E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MKLM6_RS16775 dd8fff41136dcd5260d0080d0116c9d2 357 SUPERFAMILY SSF161098 219 338 2.4E-9 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MKLM6_RS16775 dd8fff41136dcd5260d0080d0116c9d2 357 SUPERFAMILY SSF161098 114 183 2.4E-9 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MKLM6_RS16775 dd8fff41136dcd5260d0080d0116c9d2 357 Gene3D G3DSA:1.10.3720.10 2 344 6.8E-35 T 28-03-2018 MKLM6_RS17825 e498735ddee7e9d0abd6b825936185d2 225 Pfam PF00959 Phage lysozyme 78 191 1.1E-11 T 28-03-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 MKLM6_RS17825 e498735ddee7e9d0abd6b825936185d2 225 Gene3D G3DSA:1.10.530.40 37 200 3.1E-38 T 28-03-2018 IPR023347 Lysozyme domain GO:0003796 MKLM6_RS17825 e498735ddee7e9d0abd6b825936185d2 225 SUPERFAMILY SSF53955 45 200 1.28E-36 T 28-03-2018 IPR023346 Lysozyme-like domain MKLM6_RS17990 808d5b2bd7cc3d6244f2ff4a9c0ea610 212 Pfam PF00043 Glutathione S-transferase, C-terminal domain 117 192 2.4E-5 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal MKLM6_RS17990 808d5b2bd7cc3d6244f2ff4a9c0ea610 212 SUPERFAMILY SSF52833 11 111 2.84E-18 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS17990 808d5b2bd7cc3d6244f2ff4a9c0ea610 212 Pfam PF02798 Glutathione S-transferase, N-terminal domain 10 81 9.6E-13 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MKLM6_RS17990 808d5b2bd7cc3d6244f2ff4a9c0ea610 212 Gene3D G3DSA:1.20.1050.10 107 212 6.5E-16 T 28-03-2018 MKLM6_RS17990 808d5b2bd7cc3d6244f2ff4a9c0ea610 212 Gene3D G3DSA:3.40.30.10 2 106 1.8E-22 T 28-03-2018 MKLM6_RS17990 808d5b2bd7cc3d6244f2ff4a9c0ea610 212 SUPERFAMILY SSF47616 82 207 7.25E-19 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like MKLM6_RS12700 45e33ec0df4d3580a72e512866b0c57c 93 Pfam PF03658 RnfH family Ubiquitin 6 88 3.0E-31 T 28-03-2018 IPR005346 RnfH protein MKLM6_RS12700 45e33ec0df4d3580a72e512866b0c57c 93 Hamap MF_00460 Protein RnfH [rnfH]. 6 93 23.186 T 28-03-2018 IPR005346 RnfH protein MKLM6_RS12700 45e33ec0df4d3580a72e512866b0c57c 93 SUPERFAMILY SSF54285 5 79 1.92E-24 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MKLM6_RS12700 45e33ec0df4d3580a72e512866b0c57c 93 Gene3D G3DSA:3.10.20.280 1 89 4.9E-31 T 28-03-2018 IPR005346 RnfH protein MKLM6_RS03565 4dc116d59118fc3757361f7f6062e57e 503 SUPERFAMILY SSF52242 38 131 8.63E-7 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MKLM6_RS03565 4dc116d59118fc3757361f7f6062e57e 503 Pfam PF13311 Protein of unknown function (DUF4080) 358 487 4.3E-12 T 28-03-2018 IPR025288 Domain of unknown function DUF4080 MKLM6_RS03565 4dc116d59118fc3757361f7f6062e57e 503 Pfam PF04055 Radical SAM superfamily 168 322 9.1E-11 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS03565 4dc116d59118fc3757361f7f6062e57e 503 Gene3D G3DSA:3.40.50.280 5 141 5.8E-12 T 28-03-2018 MKLM6_RS03565 4dc116d59118fc3757361f7f6062e57e 503 Gene3D G3DSA:3.20.20.70 146 395 1.9E-26 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS03565 4dc116d59118fc3757361f7f6062e57e 503 SUPERFAMILY SSF102114 157 358 7.46E-37 T 28-03-2018 MKLM6_RS03565 4dc116d59118fc3757361f7f6062e57e 503 Pfam PF02310 B12 binding domain 10 123 2.6E-12 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MKLM6_RS03565 4dc116d59118fc3757361f7f6062e57e 503 SMART SM00729 163 377 2.4E-18 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MKLM6_RS10210 d7167eb4412ac403d716446057812284 273 Hamap MF_01805 Segregation and condensation protein A [scpA]. 37 267 21.522 T 28-03-2018 IPR003768 Segregation and condensation protein A MKLM6_RS10210 d7167eb4412ac403d716446057812284 273 Pfam PF02616 Segregation and condensation protein ScpA 54 264 1.9E-29 T 28-03-2018 IPR003768 Segregation and condensation protein A MKLM6_RS10210 d7167eb4412ac403d716446057812284 273 Gene3D G3DSA:1.10.10.580 200 265 3.0E-11 T 28-03-2018 MKLM6_RS12460 bf0a7bfceb8131dd1e16383cc94e7990 248 SUPERFAMILY SSF53167 1 242 1.28E-77 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MKLM6_RS12460 bf0a7bfceb8131dd1e16383cc94e7990 248 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 1 247 34.092 T 28-03-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 MKLM6_RS12460 bf0a7bfceb8131dd1e16383cc94e7990 248 Gene3D G3DSA:3.40.50.1580 1 245 5.8E-39 T 28-03-2018 MKLM6_RS12460 bf0a7bfceb8131dd1e16383cc94e7990 248 Pfam PF01048 Phosphorylase superfamily 3 241 2.3E-44 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MKLM6_RS02380 72fd33fb1e4691f67b9bf85224ad56e9 448 Pfam PF05598 Transposase domain (DUF772) 54 122 4.3E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS21400 72fd33fb1e4691f67b9bf85224ad56e9 448 Pfam PF05598 Transposase domain (DUF772) 54 122 4.3E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS06045 72fd33fb1e4691f67b9bf85224ad56e9 448 Pfam PF05598 Transposase domain (DUF772) 54 122 4.3E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS08520 72fd33fb1e4691f67b9bf85224ad56e9 448 Pfam PF05598 Transposase domain (DUF772) 54 122 4.3E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS11975 72fd33fb1e4691f67b9bf85224ad56e9 448 Pfam PF05598 Transposase domain (DUF772) 54 122 4.3E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS11675 72fd33fb1e4691f67b9bf85224ad56e9 448 Pfam PF05598 Transposase domain (DUF772) 54 122 4.3E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS09295 72fd33fb1e4691f67b9bf85224ad56e9 448 Pfam PF05598 Transposase domain (DUF772) 54 122 4.3E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS20080 72fd33fb1e4691f67b9bf85224ad56e9 448 Pfam PF05598 Transposase domain (DUF772) 54 122 4.3E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS02045 72fd33fb1e4691f67b9bf85224ad56e9 448 Pfam PF05598 Transposase domain (DUF772) 54 122 4.3E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS22130 72fd33fb1e4691f67b9bf85224ad56e9 448 Pfam PF05598 Transposase domain (DUF772) 54 122 4.3E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS08005 72fd33fb1e4691f67b9bf85224ad56e9 448 Pfam PF05598 Transposase domain (DUF772) 54 122 4.3E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS07190 e93bc86363b0550de56a9070d8045c8d 227 SMART SM00535 20 148 6.6E-50 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 MKLM6_RS07190 e93bc86363b0550de56a9070d8045c8d 227 Gene3D G3DSA:1.10.1520.10 4 149 1.0E-40 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 MKLM6_RS07190 e93bc86363b0550de56a9070d8045c8d 227 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 10 220 1.5E-69 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 MKLM6_RS07190 e93bc86363b0550de56a9070d8045c8d 227 Gene3D G3DSA:3.30.160.20 150 227 4.0E-20 T 28-03-2018 MKLM6_RS07190 e93bc86363b0550de56a9070d8045c8d 227 Hamap MF_00104 Ribonuclease 3 [rnc]. 8 219 28.82 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 MKLM6_RS07190 e93bc86363b0550de56a9070d8045c8d 227 Pfam PF00035 Double-stranded RNA binding motif 155 222 8.3E-12 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain MKLM6_RS07190 e93bc86363b0550de56a9070d8045c8d 227 SUPERFAMILY SSF54768 108 222 1.12E-23 T 28-03-2018 MKLM6_RS07190 e93bc86363b0550de56a9070d8045c8d 227 ProSitePatterns PS00517 Ribonuclease III family signature. 37 45 - T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 MKLM6_RS07190 e93bc86363b0550de56a9070d8045c8d 227 Pfam PF14622 Ribonuclease-III-like 18 138 8.5E-30 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 MKLM6_RS07190 e93bc86363b0550de56a9070d8045c8d 227 SUPERFAMILY SSF69065 8 157 5.41E-47 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 MKLM6_RS07190 e93bc86363b0550de56a9070d8045c8d 227 SMART SM00358 155 223 4.6E-21 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain MKLM6_RS16805 6291a1186ba0e087116d07cc247aa1f3 802 Gene3D G3DSA:2.30.130.40 2 118 7.4E-28 T 28-03-2018 MKLM6_RS16805 6291a1186ba0e087116d07cc247aa1f3 802 SMART SM00382 349 493 4.5E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS16805 6291a1186ba0e087116d07cc247aa1f3 802 TIGRFAM TIGR00763 lon: endopeptidase La 12 772 4.2E-298 T 28-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 MKLM6_RS16805 6291a1186ba0e087116d07cc247aa1f3 802 SMART SM00464 10 203 1.1E-67 T 28-03-2018 IPR003111 Lon, substrate-binding domain MKLM6_RS16805 6291a1186ba0e087116d07cc247aa1f3 802 SUPERFAMILY SSF88697 11 202 3.73E-48 T 28-03-2018 IPR015947 PUA-like domain MKLM6_RS16805 6291a1186ba0e087116d07cc247aa1f3 802 Gene3D G3DSA:1.10.4060.10 123 212 6.2E-30 T 28-03-2018 MKLM6_RS16805 6291a1186ba0e087116d07cc247aa1f3 802 Hamap MF_01973 Lon protease [lon]. 11 773 70.605 T 28-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 MKLM6_RS16805 6291a1186ba0e087116d07cc247aa1f3 802 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 353 490 6.6E-19 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MKLM6_RS16805 6291a1186ba0e087116d07cc247aa1f3 802 PIRSF PIRSF001174 1 776 0.0 T 28-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 MKLM6_RS16805 6291a1186ba0e087116d07cc247aa1f3 802 Gene3D G3DSA:3.40.50.300 314 491 2.4E-31 T 28-03-2018 MKLM6_RS16805 6291a1186ba0e087116d07cc247aa1f3 802 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 571 773 4.6E-96 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 MKLM6_RS16805 6291a1186ba0e087116d07cc247aa1f3 802 SUPERFAMILY SSF54211 596 771 9.48E-58 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS16805 6291a1186ba0e087116d07cc247aa1f3 802 SUPERFAMILY SSF52540 314 589 2.82E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS16805 6291a1186ba0e087116d07cc247aa1f3 802 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 11 202 3.5E-40 T 28-03-2018 IPR003111 Lon, substrate-binding domain MKLM6_RS16805 6291a1186ba0e087116d07cc247aa1f3 802 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 674 693 9.2E-55 T 28-03-2018 MKLM6_RS16805 6291a1186ba0e087116d07cc247aa1f3 802 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 596 612 9.2E-55 T 28-03-2018 MKLM6_RS16805 6291a1186ba0e087116d07cc247aa1f3 802 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 704 723 9.2E-55 T 28-03-2018 MKLM6_RS16805 6291a1186ba0e087116d07cc247aa1f3 802 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 357 376 9.2E-55 T 28-03-2018 MKLM6_RS16805 6291a1186ba0e087116d07cc247aa1f3 802 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 727 745 9.2E-55 T 28-03-2018 MKLM6_RS16805 6291a1186ba0e087116d07cc247aa1f3 802 Gene3D G3DSA:3.30.230.10 578 793 3.8E-67 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MKLM6_RS16805 6291a1186ba0e087116d07cc247aa1f3 802 Gene3D G3DSA:1.10.8.60 492 577 3.7E-33 T 28-03-2018 MKLM6_RS22540 59ae18ce4d325ae0d7f8c25309d17d2c 799 Gene3D G3DSA:3.40.50.300 274 720 4.8E-22 T 28-03-2018 MKLM6_RS22540 59ae18ce4d325ae0d7f8c25309d17d2c 799 Pfam PF11130 F pilus assembly Type-IV secretion system for plasmid transfer 10 239 1.3E-44 T 28-03-2018 IPR025955 Type-IV secretion system protein TraC/Conjugative transfer ATPase MKLM6_RS22540 59ae18ce4d325ae0d7f8c25309d17d2c 799 SUPERFAMILY SSF52540 387 713 1.02E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS22540 59ae18ce4d325ae0d7f8c25309d17d2c 799 TIGRFAM TIGR02746 TraC-F-type: type-IV secretion system protein TraC 15 791 8.1E-203 T 28-03-2018 IPR014117 Type-IV secretion system protein TraC MKLM6_RS22540 59ae18ce4d325ae0d7f8c25309d17d2c 799 Pfam PF12846 AAA-like domain 434 684 8.7E-14 T 28-03-2018 MKLM6_RS07625 72fcb6e15ce2ffc8b4a5e778a4bb145d 409 Pfam PF00375 Sodium:dicarboxylate symporter family 6 405 1.1E-117 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS07625 72fcb6e15ce2ffc8b4a5e778a4bb145d 409 SUPERFAMILY SSF118215 8 405 9.42E-106 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS07625 72fcb6e15ce2ffc8b4a5e778a4bb145d 409 PRINTS PR00173 Glutamate-aspartate symporter signature 80 105 2.0E-50 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS07625 72fcb6e15ce2ffc8b4a5e778a4bb145d 409 PRINTS PR00173 Glutamate-aspartate symporter signature 298 324 2.0E-50 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS07625 72fcb6e15ce2ffc8b4a5e778a4bb145d 409 PRINTS PR00173 Glutamate-aspartate symporter signature 333 352 2.0E-50 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS07625 72fcb6e15ce2ffc8b4a5e778a4bb145d 409 PRINTS PR00173 Glutamate-aspartate symporter signature 196 215 2.0E-50 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS07625 72fcb6e15ce2ffc8b4a5e778a4bb145d 409 PRINTS PR00173 Glutamate-aspartate symporter signature 360 380 2.0E-50 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS07625 72fcb6e15ce2ffc8b4a5e778a4bb145d 409 PRINTS PR00173 Glutamate-aspartate symporter signature 149 171 2.0E-50 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS07625 72fcb6e15ce2ffc8b4a5e778a4bb145d 409 PRINTS PR00173 Glutamate-aspartate symporter signature 231 250 2.0E-50 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS07625 72fcb6e15ce2ffc8b4a5e778a4bb145d 409 PRINTS PR00173 Glutamate-aspartate symporter signature 50 70 2.0E-50 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS07625 72fcb6e15ce2ffc8b4a5e778a4bb145d 409 Gene3D G3DSA:1.10.3860.10 1 408 1.2E-120 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS14775 fcae7c8314120446c023028de9ab1331 268 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 2 265 34.899 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MKLM6_RS14775 fcae7c8314120446c023028de9ab1331 268 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 125 1.9E-39 T 28-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MKLM6_RS14775 fcae7c8314120446c023028de9ab1331 268 PIRSF PIRSF000161 1 268 3.7E-88 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MKLM6_RS14775 fcae7c8314120446c023028de9ab1331 268 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 150 167 - T 28-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MKLM6_RS14775 fcae7c8314120446c023028de9ab1331 268 SUPERFAMILY SSF51735 236 266 1.08E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS14775 fcae7c8314120446c023028de9ab1331 268 SUPERFAMILY SSF51735 1 126 1.08E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS14775 fcae7c8314120446c023028de9ab1331 268 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 128 264 1.5E-42 T 28-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MKLM6_RS14775 fcae7c8314120446c023028de9ab1331 268 Gene3D G3DSA:3.40.50.720 1 122 1.8E-28 T 28-03-2018 MKLM6_RS14775 fcae7c8314120446c023028de9ab1331 268 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 3 265 1.3E-103 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MKLM6_RS14775 fcae7c8314120446c023028de9ab1331 268 SUPERFAMILY SSF55347 127 236 8.07E-37 T 28-03-2018 MKLM6_RS14775 fcae7c8314120446c023028de9ab1331 268 Gene3D G3DSA:3.30.360.10 126 234 4.3E-35 T 28-03-2018 MKLM6_RS05205 9786f63d8e617ef081ca29c0a1010c5e 248 ProSitePatterns PS00171 Triosephosphate isomerase active site. 164 174 - T 28-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS05205 9786f63d8e617ef081ca29c0a1010c5e 248 Gene3D G3DSA:3.20.20.70 1 248 7.9E-103 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS05205 9786f63d8e617ef081ca29c0a1010c5e 248 SUPERFAMILY SSF51351 1 247 9.82E-92 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS05205 9786f63d8e617ef081ca29c0a1010c5e 248 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 238 3.8E-69 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS05205 9786f63d8e617ef081ca29c0a1010c5e 248 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 248 40.758 T 28-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS05205 9786f63d8e617ef081ca29c0a1010c5e 248 Pfam PF00121 Triosephosphate isomerase 5 245 5.0E-93 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS01690 68fc133e2c433624f3f09ae4d623547e 182 PIRSF PIRSF004682 1 180 1.9E-51 T 28-03-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 MKLM6_RS01690 68fc133e2c433624f3f09ae4d623547e 182 SUPERFAMILY SSF56784 4 176 1.65E-43 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS01690 68fc133e2c433624f3f09ae4d623547e 182 Pfam PF13242 HAD-hyrolase-like 101 172 1.7E-12 T 28-03-2018 MKLM6_RS01690 68fc133e2c433624f3f09ae4d623547e 182 Gene3D G3DSA:3.40.50.1000 4 180 4.2E-31 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS01690 68fc133e2c433624f3f09ae4d623547e 182 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 6 146 8.7E-43 T 28-03-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 MKLM6_RS01690 68fc133e2c433624f3f09ae4d623547e 182 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 5 148 1.3E-34 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 MKLM6_RS07295 42cbb22c742a32f3a552191f26fa8766 238 Gene3D G3DSA:3.90.550.10 1 224 4.7E-42 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS07295 42cbb22c742a32f3a552191f26fa8766 238 Pfam PF00483 Nucleotidyl transferase 2 142 1.6E-19 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MKLM6_RS07295 42cbb22c742a32f3a552191f26fa8766 238 SUPERFAMILY SSF53448 1 219 1.13E-53 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS11260 5da1a3d75f9daab17b416b5f9ea93652 408 Pfam PF14524 Wzt C-terminal domain 267 366 1.4E-9 T 28-03-2018 IPR029439 Wzt, C-terminal MKLM6_RS11260 5da1a3d75f9daab17b416b5f9ea93652 408 Gene3D G3DSA:3.40.50.300 1 260 3.1E-45 T 28-03-2018 MKLM6_RS11260 5da1a3d75f9daab17b416b5f9ea93652 408 SMART SM00382 55 227 2.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS11260 5da1a3d75f9daab17b416b5f9ea93652 408 SUPERFAMILY SSF52540 41 239 3.66E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS11260 5da1a3d75f9daab17b416b5f9ea93652 408 Gene3D G3DSA:2.70.50.60 261 391 2.1E-13 T 28-03-2018 MKLM6_RS11260 5da1a3d75f9daab17b416b5f9ea93652 408 Pfam PF00005 ABC transporter 46 177 9.6E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS01990 6431a70a92008e7414468ae497ee18f3 200 SUPERFAMILY SSF55469 6 197 2.62E-46 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MKLM6_RS01990 6431a70a92008e7414468ae497ee18f3 200 Pfam PF00881 Nitroreductase family 16 162 5.0E-23 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MKLM6_RS01990 6431a70a92008e7414468ae497ee18f3 200 Gene3D G3DSA:3.40.109.10 1 199 1.5E-41 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MKLM6_RS14820 2a6ed407094fd1c6fe7a6ccb8fa5970b 408 Pfam PF08668 HDOD domain 142 339 1.5E-49 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD MKLM6_RS14820 2a6ed407094fd1c6fe7a6ccb8fa5970b 408 Gene3D G3DSA:1.10.3210.10 125 388 3.0E-39 T 28-03-2018 MKLM6_RS14820 2a6ed407094fd1c6fe7a6ccb8fa5970b 408 Pfam PF00072 Response regulator receiver domain 7 116 8.9E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14820 2a6ed407094fd1c6fe7a6ccb8fa5970b 408 SUPERFAMILY SSF52172 4 132 1.27E-26 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS14820 2a6ed407094fd1c6fe7a6ccb8fa5970b 408 SMART SM00448 5 117 1.6E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14820 2a6ed407094fd1c6fe7a6ccb8fa5970b 408 Gene3D G3DSA:3.40.50.2300 2 124 2.5E-23 T 28-03-2018 MKLM6_RS14820 2a6ed407094fd1c6fe7a6ccb8fa5970b 408 PIRSF PIRSF036883 1 388 1.1E-58 T 28-03-2018 IPR014626 Signal transduction response regulator with modified HD-GYP domain, putative MKLM6_RS14820 2a6ed407094fd1c6fe7a6ccb8fa5970b 408 SUPERFAMILY SSF109604 137 380 4.32E-52 T 28-03-2018 MKLM6_RS16140 71fc6bb7b5a29c80aa42688e15309d71 983 SUPERFAMILY SSF141868 737 982 5.36E-92 T 28-03-2018 IPR001633 EAL domain MKLM6_RS16140 71fc6bb7b5a29c80aa42688e15309d71 983 Gene3D G3DSA:3.30.70.270 559 724 2.2E-63 T 28-03-2018 MKLM6_RS16140 71fc6bb7b5a29c80aa42688e15309d71 983 SMART SM00267 550 721 7.5E-69 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS16140 71fc6bb7b5a29c80aa42688e15309d71 983 SUPERFAMILY SSF55781 379 550 6.76E-25 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS16140 71fc6bb7b5a29c80aa42688e15309d71 983 SUPERFAMILY SSF55781 233 386 5.67E-18 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS16140 71fc6bb7b5a29c80aa42688e15309d71 983 Pfam PF13185 GAF domain 406 549 1.3E-15 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS16140 71fc6bb7b5a29c80aa42688e15309d71 983 Pfam PF13185 GAF domain 231 375 1.2E-16 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS16140 71fc6bb7b5a29c80aa42688e15309d71 983 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 560 718 1.8E-47 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS16140 71fc6bb7b5a29c80aa42688e15309d71 983 Gene3D G3DSA:3.30.450.40 381 558 1.4E-24 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS16140 71fc6bb7b5a29c80aa42688e15309d71 983 Gene3D G3DSA:3.30.450.40 184 380 5.8E-23 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS16140 71fc6bb7b5a29c80aa42688e15309d71 983 Gene3D G3DSA:3.20.20.450 725 983 1.4E-103 T 28-03-2018 IPR001633 EAL domain MKLM6_RS16140 71fc6bb7b5a29c80aa42688e15309d71 983 SMART SM00065 406 558 3.3E-10 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS16140 71fc6bb7b5a29c80aa42688e15309d71 983 SMART SM00065 231 385 0.13 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS16140 71fc6bb7b5a29c80aa42688e15309d71 983 SMART SM00052 731 977 6.4E-128 T 28-03-2018 IPR001633 EAL domain MKLM6_RS16140 71fc6bb7b5a29c80aa42688e15309d71 983 SUPERFAMILY SSF55073 566 723 2.9E-52 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS16140 71fc6bb7b5a29c80aa42688e15309d71 983 Pfam PF00990 Diguanylate cyclase, GGDEF domain 561 715 8.5E-51 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS16140 71fc6bb7b5a29c80aa42688e15309d71 983 Pfam PF00563 EAL domain 739 972 1.7E-74 T 28-03-2018 IPR001633 EAL domain MKLM6_RS16140 71fc6bb7b5a29c80aa42688e15309d71 983 PIRSF PIRSF005925 373 983 2.0E-195 T 28-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase MKLM6_RS16140 71fc6bb7b5a29c80aa42688e15309d71 983 PIRSF PIRSF005925 208 391 96.0 T 28-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase MKLM6_RS17755 4659e87a6156208b7912a2eceda0d48b 133 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 130 11.377 T 28-03-2018 IPR022907 VapC family GO:0004540 MKLM6_RS17755 4659e87a6156208b7912a2eceda0d48b 133 SMART SM00670 2 121 2.1E-5 T 28-03-2018 IPR002716 PIN domain MKLM6_RS17755 4659e87a6156208b7912a2eceda0d48b 133 SUPERFAMILY SSF88723 1 131 3.08E-37 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS17755 4659e87a6156208b7912a2eceda0d48b 133 Pfam PF01850 PIN domain 4 116 2.7E-16 T 28-03-2018 IPR002716 PIN domain MKLM6_RS17755 4659e87a6156208b7912a2eceda0d48b 133 Gene3D G3DSA:3.40.50.1010 2 133 3.9E-28 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS13540 0c7046bd10f4c6d113022e4723c22318 215 SUPERFAMILY SSF52141 11 211 6.87E-45 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MKLM6_RS13540 0c7046bd10f4c6d113022e4723c22318 215 Gene3D G3DSA:3.40.470.10 5 213 1.8E-47 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MKLM6_RS13540 0c7046bd10f4c6d113022e4723c22318 215 SMART SM00987 37 204 3.8E-27 T 28-03-2018 MKLM6_RS13540 0c7046bd10f4c6d113022e4723c22318 215 SMART SM00986 37 204 3.8E-27 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MKLM6_RS13540 0c7046bd10f4c6d113022e4723c22318 215 Pfam PF03167 Uracil DNA glycosylase superfamily 38 205 7.1E-31 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MKLM6_RS07775 01132691ce7a4152712e578e22529192 357 SUPERFAMILY SSF46785 22 98 3.9E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS07775 01132691ce7a4152712e578e22529192 357 Gene3D G3DSA:1.10.10.10 12 114 1.7E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS07775 01132691ce7a4152712e578e22529192 357 Gene3D G3DSA:3.40.50.150 124 356 3.3E-24 T 28-03-2018 MKLM6_RS07775 01132691ce7a4152712e578e22529192 357 Pfam PF13847 Methyltransferase domain 177 337 2.3E-17 T 28-03-2018 IPR025714 Methyltransferase domain MKLM6_RS07775 01132691ce7a4152712e578e22529192 357 SUPERFAMILY SSF53335 117 343 1.93E-30 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS16080 53d765f617b19d95581c03b596e70ec9 566 Pfam PF01471 Putative peptidoglycan binding domain 228 289 4.4E-9 T 28-03-2018 IPR002477 Peptidoglycan binding-like MKLM6_RS16080 53d765f617b19d95581c03b596e70ec9 566 Gene3D G3DSA:1.10.101.10 216 294 3.6E-16 T 28-03-2018 IPR002477 Peptidoglycan binding-like MKLM6_RS16080 53d765f617b19d95581c03b596e70ec9 566 SUPERFAMILY SSF47090 217 295 6.98E-13 T 28-03-2018 IPR002477 Peptidoglycan binding-like MKLM6_RS16080 53d765f617b19d95581c03b596e70ec9 566 Gene3D G3DSA:2.40.440.10 310 486 2.1E-20 T 28-03-2018 MKLM6_RS16080 53d765f617b19d95581c03b596e70ec9 566 SUPERFAMILY SSF141523 315 373 2.75E-15 T 28-03-2018 MKLM6_RS16080 53d765f617b19d95581c03b596e70ec9 566 SUPERFAMILY SSF141523 424 482 2.75E-15 T 28-03-2018 MKLM6_RS16080 53d765f617b19d95581c03b596e70ec9 566 Pfam PF03734 L,D-transpeptidase catalytic domain 318 485 5.8E-27 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MKLM6_RS02485 00dfd1ded93dfe379489824e3b064ecb 334 Pfam PF13353 4Fe-4S single cluster domain 25 124 2.7E-8 T 28-03-2018 MKLM6_RS02485 00dfd1ded93dfe379489824e3b064ecb 334 Pfam PF04055 Radical SAM superfamily 22 182 6.1E-31 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS02485 00dfd1ded93dfe379489824e3b064ecb 334 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 24 35 - T 28-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 MKLM6_RS02485 00dfd1ded93dfe379489824e3b064ecb 334 SMART SM00729 18 222 5.4E-14 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MKLM6_RS02485 00dfd1ded93dfe379489824e3b064ecb 334 Gene3D G3DSA:3.20.20.70 7 334 8.7E-76 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS02485 00dfd1ded93dfe379489824e3b064ecb 334 SUPERFAMILY SSF102114 9 281 1.02E-74 T 28-03-2018 MKLM6_RS02485 00dfd1ded93dfe379489824e3b064ecb 334 Pfam PF06463 Molybdenum Cofactor Synthesis C 189 317 1.8E-36 T 28-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 MKLM6_RS02485 00dfd1ded93dfe379489824e3b064ecb 334 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 9 334 39.994 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 MKLM6_RS02485 00dfd1ded93dfe379489824e3b064ecb 334 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 9 334 6.0E-115 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 MKLM6_RS10965 91a14e707e9cf85f4276a8ede1fb800b 206 Gene3D G3DSA:2.60.40.680 16 179 2.7E-10 T 28-03-2018 MKLM6_RS15510 eb99b9999d3d9c3542ad63c17f45d256 280 Gene3D G3DSA:3.20.10.10 132 279 6.1E-42 T 28-03-2018 MKLM6_RS15510 eb99b9999d3d9c3542ad63c17f45d256 280 ProSitePatterns PS00770 Aminotransferases class-IV signature. 177 206 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 MKLM6_RS15510 eb99b9999d3d9c3542ad63c17f45d256 280 SUPERFAMILY SSF56752 4 275 6.8E-79 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 MKLM6_RS15510 eb99b9999d3d9c3542ad63c17f45d256 280 Pfam PF01063 Amino-transferase class IV 31 250 8.2E-45 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 MKLM6_RS15510 eb99b9999d3d9c3542ad63c17f45d256 280 Gene3D G3DSA:3.30.470.10 1 131 1.7E-33 T 28-03-2018 MKLM6_RS18405 1bf54b586051e7e400758b049283d181 137 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 39.176 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18405 1bf54b586051e7e400758b049283d181 137 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18405 1bf54b586051e7e400758b049283d181 137 Pfam PF00252 Ribosomal protein L16p/L10e 4 131 1.7E-49 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18405 1bf54b586051e7e400758b049283d181 137 PRINTS PR00060 Ribosomal protein L16 signature 42 53 4.1E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18405 1bf54b586051e7e400758b049283d181 137 PRINTS PR00060 Ribosomal protein L16 signature 88 117 4.1E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18405 1bf54b586051e7e400758b049283d181 137 PRINTS PR00060 Ribosomal protein L16 signature 24 36 4.1E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18405 1bf54b586051e7e400758b049283d181 137 PRINTS PR00060 Ribosomal protein L16 signature 58 87 4.1E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18405 1bf54b586051e7e400758b049283d181 137 SUPERFAMILY SSF54686 1 133 6.54E-55 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18405 1bf54b586051e7e400758b049283d181 137 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.0E-60 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18405 1bf54b586051e7e400758b049283d181 137 Gene3D G3DSA:3.90.1170.10 1 136 2.5E-50 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18405 1bf54b586051e7e400758b049283d181 137 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS21945 59cfd7ce653b03e6ca489f2e89701120 157 PIRSF PIRSF021700 1 156 1.5E-61 T 28-03-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase MKLM6_RS21945 59cfd7ce653b03e6ca489f2e89701120 157 SUPERFAMILY SSF54593 3 154 1.08E-45 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MKLM6_RS21945 59cfd7ce653b03e6ca489f2e89701120 157 Gene3D G3DSA:3.10.180.10 1 122 6.0E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MKLM6_RS21945 59cfd7ce653b03e6ca489f2e89701120 157 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 3 116 4.3E-43 T 28-03-2018 IPR028973 PhnB-like MKLM6_RS20025 e264395558687cb8712ad035e39224eb 217 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 32 48 - T 28-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site MKLM6_RS20025 e264395558687cb8712ad035e39224eb 217 Pfam PF00027 Cyclic nucleotide-binding domain 24 111 1.3E-16 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain MKLM6_RS20025 e264395558687cb8712ad035e39224eb 217 Pfam PF00325 Bacterial regulatory proteins, crp family 173 204 1.4E-13 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MKLM6_RS20025 e264395558687cb8712ad035e39224eb 217 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 189 204 1.4E-7 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MKLM6_RS20025 e264395558687cb8712ad035e39224eb 217 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 173 189 1.4E-7 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MKLM6_RS20025 e264395558687cb8712ad035e39224eb 217 SUPERFAMILY SSF51206 10 144 3.14E-25 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like MKLM6_RS20025 e264395558687cb8712ad035e39224eb 217 SUPERFAMILY SSF46785 146 214 2.62E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS20025 e264395558687cb8712ad035e39224eb 217 SMART SM00419 167 215 7.8E-15 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MKLM6_RS20025 e264395558687cb8712ad035e39224eb 217 Gene3D G3DSA:1.10.10.10 152 217 6.8E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS20025 e264395558687cb8712ad035e39224eb 217 Gene3D G3DSA:2.60.120.10 2 151 3.1E-23 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS20025 e264395558687cb8712ad035e39224eb 217 SMART SM00100 5 124 1.0E-15 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain MKLM6_RS20025 e264395558687cb8712ad035e39224eb 217 ProSitePatterns PS00042 Crp-type HTH domain signature. 175 198 - T 28-03-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 MKLM6_RS11970 c90b26cdb76aff16b4dc260740210c7e 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 208 4.1E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS11970 c90b26cdb76aff16b4dc260740210c7e 224 SMART SM00421 153 210 9.8E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS11970 c90b26cdb76aff16b4dc260740210c7e 224 SUPERFAMILY SSF46894 146 216 4.76E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MKLM6_RS11970 c90b26cdb76aff16b4dc260740210c7e 224 Pfam PF00072 Response regulator receiver domain 3 114 1.3E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS11970 c90b26cdb76aff16b4dc260740210c7e 224 SMART SM00448 1 114 2.9E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS11970 c90b26cdb76aff16b4dc260740210c7e 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 5.0E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS11970 c90b26cdb76aff16b4dc260740210c7e 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 5.0E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS11970 c90b26cdb76aff16b4dc260740210c7e 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 5.0E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS11970 c90b26cdb76aff16b4dc260740210c7e 224 SUPERFAMILY SSF52172 2 127 2.85E-28 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS11970 c90b26cdb76aff16b4dc260740210c7e 224 Gene3D G3DSA:1.10.10.10 125 217 1.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS11970 c90b26cdb76aff16b4dc260740210c7e 224 Gene3D G3DSA:3.40.50.2300 1 124 7.9E-27 T 28-03-2018 MKLM6_RS19775 ef605b420723e1e3bf2938074e319f30 507 Gene3D G3DSA:1.10.579.10 285 464 5.4E-47 T 28-03-2018 MKLM6_RS19775 ef605b420723e1e3bf2938074e319f30 507 SUPERFAMILY SSF52425 3 167 6.41E-40 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 MKLM6_RS19775 ef605b420723e1e3bf2938074e319f30 507 Pfam PF03441 FAD binding domain of DNA photolyase 264 461 6.3E-52 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 MKLM6_RS19775 ef605b420723e1e3bf2938074e319f30 507 SUPERFAMILY SSF48173 187 465 2.09E-75 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 MKLM6_RS19775 ef605b420723e1e3bf2938074e319f30 507 Gene3D G3DSA:1.25.40.80 129 284 2.9E-19 T 28-03-2018 MKLM6_RS19775 ef605b420723e1e3bf2938074e319f30 507 Pfam PF00875 DNA photolyase 5 127 5.4E-24 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 MKLM6_RS19775 ef605b420723e1e3bf2938074e319f30 507 Gene3D G3DSA:3.40.50.620 1 128 2.3E-29 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS11600 efb373b0717e893000f420d92806d0c9 198 Gene3D G3DSA:3.30.530.20 15 194 2.9E-35 T 28-03-2018 IPR023393 START-like domain MKLM6_RS11600 efb373b0717e893000f420d92806d0c9 198 SUPERFAMILY SSF55961 28 184 1.31E-26 T 28-03-2018 MKLM6_RS11600 efb373b0717e893000f420d92806d0c9 198 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 27 185 2.2E-28 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase MKLM6_RS02170 e1b0221c92c863090c09e89c0c30b341 558 Pfam PF13584 Oxygen tolerance 18 473 6.4E-109 T 28-03-2018 IPR025738 Aerotolerance-related protein BatD MKLM6_RS10420 bbabbef63c2272772291a48ad7add5f0 345 Gene3D G3DSA:3.40.250.10 128 323 6.0E-19 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS10420 bbabbef63c2272772291a48ad7add5f0 345 SMART SM00450 137 277 3.1E-7 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS10420 bbabbef63c2272772291a48ad7add5f0 345 SUPERFAMILY SSF52821 218 270 2.49E-18 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS10420 bbabbef63c2272772291a48ad7add5f0 345 SUPERFAMILY SSF52821 148 175 2.49E-18 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS10420 bbabbef63c2272772291a48ad7add5f0 345 Pfam PF00581 Rhodanese-like domain 147 269 2.9E-8 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS10825 ad94113f227ee1ebfafe7bc062cd0120 101 SUPERFAMILY SSF47729 1 91 5.0E-29 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 MKLM6_RS10825 ad94113f227ee1ebfafe7bc062cd0120 101 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 2 91 2.6E-42 T 28-03-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 MKLM6_RS10825 ad94113f227ee1ebfafe7bc062cd0120 101 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 2.0E-18 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MKLM6_RS10825 ad94113f227ee1ebfafe7bc062cd0120 101 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 2.0E-18 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MKLM6_RS10825 ad94113f227ee1ebfafe7bc062cd0120 101 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 2.0E-18 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MKLM6_RS10825 ad94113f227ee1ebfafe7bc062cd0120 101 Pfam PF00216 Bacterial DNA-binding protein 1 90 2.4E-27 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MKLM6_RS10825 ad94113f227ee1ebfafe7bc062cd0120 101 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 MKLM6_RS10825 ad94113f227ee1ebfafe7bc062cd0120 101 Hamap MF_00381 Integration host factor subunit beta [ihfB]. 1 94 29.029 T 28-03-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 MKLM6_RS10825 ad94113f227ee1ebfafe7bc062cd0120 101 Gene3D G3DSA:4.10.520.10 1 94 5.3E-29 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 MKLM6_RS10825 ad94113f227ee1ebfafe7bc062cd0120 101 SMART SM00411 1 91 7.3E-39 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MKLM6_RS05180 9afa46c27587befa382c9480f058d3a3 158 Gene3D G3DSA:1.10.287.180 3 75 1.5E-31 T 28-03-2018 MKLM6_RS05180 9afa46c27587befa382c9480f058d3a3 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 156 33.383 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 MKLM6_RS05180 9afa46c27587befa382c9480f058d3a3 158 Pfam PF03449 Transcription elongation factor, N-terminal 5 74 1.8E-30 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 MKLM6_RS05180 9afa46c27587befa382c9480f058d3a3 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 MKLM6_RS05180 9afa46c27587befa382c9480f058d3a3 158 Gene3D G3DSA:3.10.50.30 76 158 6.9E-29 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MKLM6_RS05180 9afa46c27587befa382c9480f058d3a3 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 157 2.7E-30 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MKLM6_RS05180 9afa46c27587befa382c9480f058d3a3 158 SUPERFAMILY SSF46557 3 78 7.32E-28 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 MKLM6_RS05180 9afa46c27587befa382c9480f058d3a3 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 156 1.9E-58 T 28-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 MKLM6_RS05180 9afa46c27587befa382c9480f058d3a3 158 SUPERFAMILY SSF54534 82 157 3.53E-24 T 28-03-2018 MKLM6_RS05180 9afa46c27587befa382c9480f058d3a3 158 PIRSF PIRSF006092 1 158 2.6E-53 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 MKLM6_RS05850 e56caf485b0bbc84b44de1c5ac023ee0 514 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 5 498 1.3E-221 T 28-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MKLM6_RS05850 e56caf485b0bbc84b44de1c5ac023ee0 514 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MKLM6_RS05850 e56caf485b0bbc84b44de1c5ac023ee0 514 SUPERFAMILY SSF51569 1 291 3.66E-101 T 28-03-2018 MKLM6_RS05850 e56caf485b0bbc84b44de1c5ac023ee0 514 SMART SM00917 370 501 4.0E-39 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MKLM6_RS05850 e56caf485b0bbc84b44de1c5ac023ee0 514 Gene3D G3DSA:3.20.20.70 1 335 9.4E-113 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS05850 e56caf485b0bbc84b44de1c5ac023ee0 514 Pfam PF00682 HMGL-like 5 273 1.9E-101 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MKLM6_RS05850 e56caf485b0bbc84b44de1c5ac023ee0 514 SUPERFAMILY SSF110921 391 500 6.54E-24 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MKLM6_RS05850 e56caf485b0bbc84b44de1c5ac023ee0 514 Pfam PF08502 LeuA allosteric (dimerisation) domain 370 500 1.3E-34 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MKLM6_RS05850 e56caf485b0bbc84b44de1c5ac023ee0 514 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 199 212 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MKLM6_RS05850 e56caf485b0bbc84b44de1c5ac023ee0 514 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 2 510 44.035 T 28-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MKLM6_RS02985 2e852f348b962cac95e72398fb25d143 164 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 130 2.0E-26 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MKLM6_RS02985 2e852f348b962cac95e72398fb25d143 164 SUPERFAMILY SSF55083 2 153 7.32E-44 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MKLM6_RS02985 2e852f348b962cac95e72398fb25d143 164 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 5 130 2.6E-29 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MKLM6_RS02985 2e852f348b962cac95e72398fb25d143 164 Gene3D G3DSA:3.30.70.560 1 164 5.5E-45 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MKLM6_RS02430 e2d2e33ccf440c59174871f6ae0e60e4 298 Pfam PF01259 SAICAR synthetase 18 272 3.8E-102 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MKLM6_RS02430 e2d2e33ccf440c59174871f6ae0e60e4 298 Gene3D G3DSA:3.30.200.20 8 115 2.8E-36 T 28-03-2018 MKLM6_RS02430 e2d2e33ccf440c59174871f6ae0e60e4 298 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 15 297 26.572 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MKLM6_RS02430 e2d2e33ccf440c59174871f6ae0e60e4 298 Gene3D G3DSA:3.30.470.20 116 253 2.8E-54 T 28-03-2018 MKLM6_RS02430 e2d2e33ccf440c59174871f6ae0e60e4 298 SUPERFAMILY SSF56104 7 297 1.6E-100 T 28-03-2018 MKLM6_RS02430 e2d2e33ccf440c59174871f6ae0e60e4 298 ProSitePatterns PS01057 SAICAR synthetase signature 1. 110 124 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MKLM6_RS02430 e2d2e33ccf440c59174871f6ae0e60e4 298 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 18 291 4.8E-80 T 28-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 MKLM6_RS02430 e2d2e33ccf440c59174871f6ae0e60e4 298 ProSitePatterns PS01058 SAICAR synthetase signature 2. 209 217 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MKLM6_RS22625 79ba18b3a673f928af55591871e7f897 1906 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1311 1347 7.5E-9 T 28-03-2018 IPR006530 YD repeat MKLM6_RS22625 79ba18b3a673f928af55591871e7f897 1906 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1436 1474 5.4E-6 T 28-03-2018 IPR006530 YD repeat MKLM6_RS22625 79ba18b3a673f928af55591871e7f897 1906 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1227 1267 5.7E-4 T 28-03-2018 IPR006530 YD repeat MKLM6_RS22625 79ba18b3a673f928af55591871e7f897 1906 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1353 1393 3.0E-6 T 28-03-2018 IPR006530 YD repeat MKLM6_RS22625 79ba18b3a673f928af55591871e7f897 1906 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1082 1111 0.0025 T 28-03-2018 IPR006530 YD repeat MKLM6_RS22625 79ba18b3a673f928af55591871e7f897 1906 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1185 1213 1.2E-5 T 28-03-2018 IPR006530 YD repeat MKLM6_RS22625 79ba18b3a673f928af55591871e7f897 1906 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1395 1434 3.3E-6 T 28-03-2018 IPR006530 YD repeat MKLM6_RS22625 79ba18b3a673f928af55591871e7f897 1906 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1415 1443 7.3E-9 T 28-03-2018 IPR006530 YD repeat MKLM6_RS22625 79ba18b3a673f928af55591871e7f897 1906 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1153 1183 0.0013 T 28-03-2018 IPR006530 YD repeat MKLM6_RS22625 79ba18b3a673f928af55591871e7f897 1906 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1272 1298 7.0E-4 T 28-03-2018 IPR006530 YD repeat MKLM6_RS22625 79ba18b3a673f928af55591871e7f897 1906 SUPERFAMILY SSF54001 147 204 1.67E-10 T 28-03-2018 MKLM6_RS22625 79ba18b3a673f928af55591871e7f897 1906 SUPERFAMILY SSF54001 253 288 1.67E-10 T 28-03-2018 MKLM6_RS22625 79ba18b3a673f928af55591871e7f897 1906 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1688 1766 4.5E-25 T 28-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 MKLM6_RS22625 79ba18b3a673f928af55591871e7f897 1906 PRINTS PR00394 RHS protein signature 1655 1675 5.2E-6 T 28-03-2018 IPR001826 RHS protein MKLM6_RS22625 79ba18b3a673f928af55591871e7f897 1906 PRINTS PR00394 RHS protein signature 1710 1730 5.2E-6 T 28-03-2018 IPR001826 RHS protein MKLM6_RS22625 79ba18b3a673f928af55591871e7f897 1906 PRINTS PR00394 RHS protein signature 1733 1752 5.2E-6 T 28-03-2018 IPR001826 RHS protein MKLM6_RS22625 79ba18b3a673f928af55591871e7f897 1906 Pfam PF01841 Transglutaminase-like superfamily 141 220 6.0E-7 T 28-03-2018 IPR002931 Transglutaminase-like MKLM6_RS22625 79ba18b3a673f928af55591871e7f897 1906 Pfam PF05593 RHS Repeat 1185 1214 4.3E-6 T 28-03-2018 IPR031325 RHS repeat MKLM6_RS22625 79ba18b3a673f928af55591871e7f897 1906 Pfam PF05593 RHS Repeat 1353 1388 1.0E-4 T 28-03-2018 IPR031325 RHS repeat MKLM6_RS22625 79ba18b3a673f928af55591871e7f897 1906 Pfam PF05593 RHS Repeat 1415 1449 1.8E-12 T 28-03-2018 IPR031325 RHS repeat MKLM6_RS22625 79ba18b3a673f928af55591871e7f897 1906 Pfam PF05593 RHS Repeat 1311 1346 3.1E-9 T 28-03-2018 IPR031325 RHS repeat MKLM6_RS18910 c59039d1deefda4ee25513cfb4bdc2e5 198 SUPERFAMILY SSF48498 84 191 1.49E-20 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MKLM6_RS18910 c59039d1deefda4ee25513cfb4bdc2e5 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 9.9E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MKLM6_RS18910 c59039d1deefda4ee25513cfb4bdc2e5 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 9.9E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MKLM6_RS18910 c59039d1deefda4ee25513cfb4bdc2e5 198 SUPERFAMILY SSF46689 5 77 5.64E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS18910 c59039d1deefda4ee25513cfb4bdc2e5 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 2.8E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MKLM6_RS18910 c59039d1deefda4ee25513cfb4bdc2e5 198 Pfam PF16925 Bacterial transcriptional repressor C-terminal 85 193 6.4E-26 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MKLM6_RS18910 c59039d1deefda4ee25513cfb4bdc2e5 198 Gene3D G3DSA:1.10.357.10 62 193 2.6E-22 T 28-03-2018 MKLM6_RS18910 c59039d1deefda4ee25513cfb4bdc2e5 198 Gene3D G3DSA:1.10.10.60 9 61 1.2E-15 T 28-03-2018 MKLM6_RS21825 6b69aae62e0675edb14f8a104f0b6014 287 SUPERFAMILY SSF53474 14 237 1.82E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS21825 6b69aae62e0675edb14f8a104f0b6014 287 Gene3D G3DSA:3.40.50.1820 5 271 6.0E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS18890 17a9fb6846a3e83dc2f753f69ae6f2f8 478 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 145 159 - T 28-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 MKLM6_RS18890 17a9fb6846a3e83dc2f753f69ae6f2f8 478 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 4 477 38.9 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 MKLM6_RS18890 17a9fb6846a3e83dc2f753f69ae6f2f8 478 SUPERFAMILY SSF55931 6 297 7.19E-124 T 28-03-2018 MKLM6_RS18890 17a9fb6846a3e83dc2f753f69ae6f2f8 478 SMART SM00845 329 476 1.1E-77 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 MKLM6_RS18890 17a9fb6846a3e83dc2f753f69ae6f2f8 478 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 4 476 3.0E-179 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 MKLM6_RS18890 17a9fb6846a3e83dc2f753f69ae6f2f8 478 Pfam PF02934 GatB/GatE catalytic domain 7 288 8.7E-115 T 28-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 MKLM6_RS18890 17a9fb6846a3e83dc2f753f69ae6f2f8 478 Gene3D G3DSA:1.10.10.410 416 477 7.9E-22 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal MKLM6_RS18890 17a9fb6846a3e83dc2f753f69ae6f2f8 478 Pfam PF02637 GatB domain 329 476 4.5E-53 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 MKLM6_RS18890 17a9fb6846a3e83dc2f753f69ae6f2f8 478 SUPERFAMILY SSF89095 298 402 3.01E-32 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 MKLM6_RS00800 bd32bbe4f1f7d08e08791357453d285a 90 PIRSF PIRSF029827 1 90 2.4E-35 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MKLM6_RS00800 bd32bbe4f1f7d08e08791357453d285a 90 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 25.866 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MKLM6_RS00800 bd32bbe4f1f7d08e08791357453d285a 90 Gene3D G3DSA:1.10.3880.10 2 89 2.7E-36 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MKLM6_RS00800 bd32bbe4f1f7d08e08791357453d285a 90 Pfam PF04362 Bacterial Fe(2+) trafficking 1 87 6.6E-38 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MKLM6_RS00800 bd32bbe4f1f7d08e08791357453d285a 90 SUPERFAMILY SSF111148 1 89 2.62E-34 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MKLM6_RS00800 bd32bbe4f1f7d08e08791357453d285a 90 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 75 9.0E-28 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MKLM6_RS03980 4ef4b3f6b413dc521e122e355aaf3697 426 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 17 419 50.75 T 28-03-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 MKLM6_RS03980 4ef4b3f6b413dc521e122e355aaf3697 426 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 113 121 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 MKLM6_RS03980 4ef4b3f6b413dc521e122e355aaf3697 426 SUPERFAMILY SSF53448 18 290 2.82E-78 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS03980 4ef4b3f6b413dc521e122e355aaf3697 426 SUPERFAMILY SSF53448 357 373 2.82E-78 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS03980 4ef4b3f6b413dc521e122e355aaf3697 426 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 20 393 1.7E-157 T 28-03-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 MKLM6_RS03980 4ef4b3f6b413dc521e122e355aaf3697 426 Gene3D G3DSA:2.160.10.10 310 423 5.5E-11 T 28-03-2018 MKLM6_RS03980 4ef4b3f6b413dc521e122e355aaf3697 426 SUPERFAMILY SSF51161 308 411 5.6E-18 T 28-03-2018 IPR011004 Trimeric LpxA-like MKLM6_RS03980 4ef4b3f6b413dc521e122e355aaf3697 426 Pfam PF00483 Nucleotidyl transferase 22 286 3.9E-64 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MKLM6_RS03980 4ef4b3f6b413dc521e122e355aaf3697 426 Gene3D G3DSA:3.90.550.10 10 290 3.9E-59 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS13820 41c3ba85d450ff171b01009c7498b060 80 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 3 64 28.121 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 MKLM6_RS13820 41c3ba85d450ff171b01009c7498b060 80 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 5 64 1.8E-29 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 MKLM6_RS13820 41c3ba85d450ff171b01009c7498b060 80 Gene3D G3DSA:2.30.30.100 4 73 2.0E-33 T 28-03-2018 MKLM6_RS13820 41c3ba85d450ff171b01009c7498b060 80 Pfam PF17209 Hfq protein 7 68 1.4E-30 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 MKLM6_RS13820 41c3ba85d450ff171b01009c7498b060 80 SUPERFAMILY SSF50182 6 69 2.34E-24 T 28-03-2018 IPR010920 LSM domain MKLM6_RS14215 4481e59d5de64c67371f5b03c49e7c04 407 Pfam PF00483 Nucleotidyl transferase 8 275 7.5E-60 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MKLM6_RS14215 4481e59d5de64c67371f5b03c49e7c04 407 SUPERFAMILY SSF53448 4 279 7.04E-71 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS14215 4481e59d5de64c67371f5b03c49e7c04 407 SUPERFAMILY SSF53448 307 322 7.04E-71 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS14215 4481e59d5de64c67371f5b03c49e7c04 407 Gene3D G3DSA:2.160.10.10 276 398 8.3E-14 T 28-03-2018 MKLM6_RS14215 4481e59d5de64c67371f5b03c49e7c04 407 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 3 402 42.872 T 28-03-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 MKLM6_RS14215 4481e59d5de64c67371f5b03c49e7c04 407 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 326 359 0.0018 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS14215 4481e59d5de64c67371f5b03c49e7c04 407 SUPERFAMILY SSF51161 296 399 3.74E-16 T 28-03-2018 IPR011004 Trimeric LpxA-like MKLM6_RS14215 4481e59d5de64c67371f5b03c49e7c04 407 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 12 31 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 MKLM6_RS14215 4481e59d5de64c67371f5b03c49e7c04 407 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 6 375 7.1E-129 T 28-03-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 MKLM6_RS14215 4481e59d5de64c67371f5b03c49e7c04 407 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 98 106 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 MKLM6_RS14215 4481e59d5de64c67371f5b03c49e7c04 407 Gene3D G3DSA:3.90.550.10 1 275 1.8E-59 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS13440 22af8f4ac5daa4008881134597fed25c 104 SUPERFAMILY SSF88946 9 89 1.53E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS13440 22af8f4ac5daa4008881134597fed25c 104 Pfam PF04542 Sigma-70 region 2 11 76 9.4E-13 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS13440 22af8f4ac5daa4008881134597fed25c 104 Gene3D G3DSA:1.10.1740.10 5 80 3.7E-14 T 28-03-2018 MKLM6_RS00200 ef04c696142a1c05c8ed7c0c9fd6bd89 306 Pfam PF00005 ABC transporter 15 157 6.7E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS00200 ef04c696142a1c05c8ed7c0c9fd6bd89 306 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS00200 ef04c696142a1c05c8ed7c0c9fd6bd89 306 SMART SM00382 24 204 1.8E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS00200 ef04c696142a1c05c8ed7c0c9fd6bd89 306 SUPERFAMILY SSF52540 1 222 3.01E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS00200 ef04c696142a1c05c8ed7c0c9fd6bd89 306 Gene3D G3DSA:3.40.50.300 1 275 6.8E-60 T 28-03-2018 MKLM6_RS14285 3c8d49d2ca049d98d8dce818b9a17488 761 Pfam PF00563 EAL domain 501 743 1.8E-73 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14285 3c8d49d2ca049d98d8dce818b9a17488 761 SMART SM00267 313 485 2.0E-67 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS14285 3c8d49d2ca049d98d8dce818b9a17488 761 SUPERFAMILY SSF55781 147 320 9.53E-27 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS14285 3c8d49d2ca049d98d8dce818b9a17488 761 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 320 483 3.7E-44 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS14285 3c8d49d2ca049d98d8dce818b9a17488 761 SMART SM00052 495 748 5.0E-119 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14285 3c8d49d2ca049d98d8dce818b9a17488 761 Gene3D G3DSA:3.30.450.40 118 321 3.9E-25 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS14285 3c8d49d2ca049d98d8dce818b9a17488 761 Pfam PF13185 GAF domain 169 305 3.2E-16 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS14285 3c8d49d2ca049d98d8dce818b9a17488 761 SMART SM00065 167 314 1.5E-14 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS14285 3c8d49d2ca049d98d8dce818b9a17488 761 Gene3D G3DSA:3.10.580.10 12 117 1.7E-7 T 28-03-2018 MKLM6_RS14285 3c8d49d2ca049d98d8dce818b9a17488 761 SUPERFAMILY SSF141868 500 755 1.31E-90 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14285 3c8d49d2ca049d98d8dce818b9a17488 761 Gene3D G3DSA:3.20.20.450 493 750 1.1E-99 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14285 3c8d49d2ca049d98d8dce818b9a17488 761 Pfam PF00990 Diguanylate cyclase, GGDEF domain 324 481 4.0E-51 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS14285 3c8d49d2ca049d98d8dce818b9a17488 761 Gene3D G3DSA:3.30.70.270 325 492 1.4E-62 T 28-03-2018 MKLM6_RS14285 3c8d49d2ca049d98d8dce818b9a17488 761 SUPERFAMILY SSF55073 329 487 2.35E-51 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS14285 3c8d49d2ca049d98d8dce818b9a17488 761 SUPERFAMILY SSF54631 38 116 2.07E-7 T 28-03-2018 MKLM6_RS13185 f7b56b4b7497ce4d5ec973bb27814d64 148 Pfam PF04773 FecR protein 59 145 2.9E-10 T 28-03-2018 IPR006860 FecR protein MKLM6_RS21725 c1020a2158d8fb4a32bfbb987e77317c 70 Gene3D G3DSA:3.40.1620.10 6 59 1.0E-8 T 28-03-2018 MKLM6_RS21725 c1020a2158d8fb4a32bfbb987e77317c 70 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 6 54 2.7E-9 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MKLM6_RS21725 c1020a2158d8fb4a32bfbb987e77317c 70 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 13 55 5.2E-8 T 28-03-2018 MKLM6_RS21725 c1020a2158d8fb4a32bfbb987e77317c 70 SUPERFAMILY SSF143120 6 58 1.03E-10 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MKLM6_RS01655 7d722f5319655cd08eb1608eaab60196 1037 Gene3D G3DSA:3.30.70.1430 548 649 2.5E-17 T 28-03-2018 MKLM6_RS01655 7d722f5319655cd08eb1608eaab60196 1037 SUPERFAMILY SSF82866 291 488 3.14E-45 T 28-03-2018 MKLM6_RS01655 7d722f5319655cd08eb1608eaab60196 1037 Gene3D G3DSA:3.30.2090.10 180 267 6.0E-13 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS01655 7d722f5319655cd08eb1608eaab60196 1037 PRINTS PR00702 Acriflavin resistance protein family signature 532 549 7.4E-52 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS01655 7d722f5319655cd08eb1608eaab60196 1037 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 7.4E-52 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS01655 7d722f5319655cd08eb1608eaab60196 1037 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 7.4E-52 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS01655 7d722f5319655cd08eb1608eaab60196 1037 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 7.4E-52 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS01655 7d722f5319655cd08eb1608eaab60196 1037 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 7.4E-52 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS01655 7d722f5319655cd08eb1608eaab60196 1037 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 7.4E-52 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS01655 7d722f5319655cd08eb1608eaab60196 1037 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 7.4E-52 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS01655 7d722f5319655cd08eb1608eaab60196 1037 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 7.4E-52 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS01655 7d722f5319655cd08eb1608eaab60196 1037 Gene3D G3DSA:3.30.70.1430 40 140 4.2E-24 T 28-03-2018 MKLM6_RS01655 7d722f5319655cd08eb1608eaab60196 1037 SUPERFAMILY SSF82714 698 789 8.24E-7 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS01655 7d722f5319655cd08eb1608eaab60196 1037 Pfam PF00873 AcrB/AcrD/AcrF family 5 1008 8.1E-224 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS01655 7d722f5319655cd08eb1608eaab60196 1037 SUPERFAMILY SSF82693 41 132 1.62E-20 T 28-03-2018 MKLM6_RS01655 7d722f5319655cd08eb1608eaab60196 1037 SUPERFAMILY SSF82693 545 647 6.1E-11 T 28-03-2018 MKLM6_RS01655 7d722f5319655cd08eb1608eaab60196 1037 SUPERFAMILY SSF82693 267 311 2.35E-12 T 28-03-2018 MKLM6_RS01655 7d722f5319655cd08eb1608eaab60196 1037 SUPERFAMILY SSF82693 137 181 2.35E-12 T 28-03-2018 MKLM6_RS01655 7d722f5319655cd08eb1608eaab60196 1037 Gene3D G3DSA:3.30.2090.10 697 790 2.8E-11 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS01655 7d722f5319655cd08eb1608eaab60196 1037 Gene3D G3DSA:1.20.1640.10 270 491 1.3E-39 T 28-03-2018 MKLM6_RS01655 7d722f5319655cd08eb1608eaab60196 1037 Gene3D G3DSA:1.20.1640.10 798 1011 1.5E-39 T 28-03-2018 MKLM6_RS01655 7d722f5319655cd08eb1608eaab60196 1037 SUPERFAMILY SSF82714 183 264 3.27E-11 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS01655 7d722f5319655cd08eb1608eaab60196 1037 SUPERFAMILY SSF82866 787 1015 3.53E-45 T 28-03-2018 MKLM6_RS20825 044cc79d433e948ee3d938ada88781b1 1083 SMART SM00304 479 531 4.2 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS20825 044cc79d433e948ee3d938ada88781b1 1083 SMART SM00304 661 713 2.3 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS20825 044cc79d433e948ee3d938ada88781b1 1083 SMART SM00304 570 622 7.4 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS20825 044cc79d433e948ee3d938ada88781b1 1083 SMART SM00304 752 804 8.3 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS20825 044cc79d433e948ee3d938ada88781b1 1083 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 865 1006 6.3E-36 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS20825 044cc79d433e948ee3d938ada88781b1 1083 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 23 111 7.6E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS20825 044cc79d433e948ee3d938ada88781b1 1083 Gene3D G3DSA:1.20.1420.10 641 729 4.0E-17 T 28-03-2018 MKLM6_RS20825 044cc79d433e948ee3d938ada88781b1 1083 Gene3D G3DSA:1.20.1420.10 730 850 2.1E-5 T 28-03-2018 MKLM6_RS20825 044cc79d433e948ee3d938ada88781b1 1083 Gene3D G3DSA:1.20.1420.10 213 640 8.7E-15 T 28-03-2018 MKLM6_RS20825 044cc79d433e948ee3d938ada88781b1 1083 SMART SM00283 805 1038 2.8E-76 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS20825 044cc79d433e948ee3d938ada88781b1 1083 SUPERFAMILY SSF58104 772 1039 6.02E-65 T 28-03-2018 MKLM6_RS20825 044cc79d433e948ee3d938ada88781b1 1083 Gene3D G3DSA:3.40.50.10600 9 128 4.6E-26 T 28-03-2018 MKLM6_RS20825 044cc79d433e948ee3d938ada88781b1 1083 SUPERFAMILY SSF55785 22 113 6.46E-24 T 28-03-2018 IPR000014 PAS domain MKLM6_RS20825 044cc79d433e948ee3d938ada88781b1 1083 Pfam PF08447 PAS fold 31 111 1.5E-11 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS20825 044cc79d433e948ee3d938ada88781b1 1083 Gene3D G3DSA:1.10.287.950 860 1042 1.1E-46 T 28-03-2018 MKLM6_RS20825 044cc79d433e948ee3d938ada88781b1 1083 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 819 848 8.2E-27 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MKLM6_RS20825 044cc79d433e948ee3d938ada88781b1 1083 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 896 923 8.2E-27 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MKLM6_RS20825 044cc79d433e948ee3d938ada88781b1 1083 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 925 954 8.2E-27 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MKLM6_RS15270 1a8b42a70cf43a975293d6ca405fd543 518 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 7 518 2.5E-238 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MKLM6_RS15270 1a8b42a70cf43a975293d6ca405fd543 518 Gene3D G3DSA:3.40.50.1380 2 194 9.6E-78 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain MKLM6_RS15270 1a8b42a70cf43a975293d6ca405fd543 518 SMART SM00798 135 450 6.3E-210 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MKLM6_RS15270 1a8b42a70cf43a975293d6ca405fd543 518 SUPERFAMILY SSF52335 5 196 1.15E-68 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain MKLM6_RS15270 1a8b42a70cf43a975293d6ca405fd543 518 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 5 518 44.95 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MKLM6_RS15270 1a8b42a70cf43a975293d6ca405fd543 518 SMART SM00851 17 130 1.9E-61 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain MKLM6_RS15270 1a8b42a70cf43a975293d6ca405fd543 518 Gene3D G3DSA:3.40.140.20 364 508 1.6E-51 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MKLM6_RS15270 1a8b42a70cf43a975293d6ca405fd543 518 Pfam PF01808 AICARFT/IMPCHase bienzyme 135 449 7.1E-119 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MKLM6_RS15270 1a8b42a70cf43a975293d6ca405fd543 518 Pfam PF02142 MGS-like domain 17 130 7.1E-28 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain MKLM6_RS15270 1a8b42a70cf43a975293d6ca405fd543 518 Gene3D G3DSA:3.40.140.20 214 362 1.3E-51 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MKLM6_RS15270 1a8b42a70cf43a975293d6ca405fd543 518 PIRSF PIRSF000414 1 518 6.1E-221 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MKLM6_RS15270 1a8b42a70cf43a975293d6ca405fd543 518 SUPERFAMILY SSF53927 209 518 1.4E-125 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 MKLM6_RS10730 06274d8bd4174865fd5bedd01a3c11fc 293 Pfam PF00701 Dihydrodipicolinate synthetase family 2 287 1.8E-103 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MKLM6_RS10730 06274d8bd4174865fd5bedd01a3c11fc 293 SMART SM01130 1 289 2.3E-141 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MKLM6_RS10730 06274d8bd4174865fd5bedd01a3c11fc 293 PIRSF PIRSF001365 1 291 3.9E-94 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MKLM6_RS10730 06274d8bd4174865fd5bedd01a3c11fc 293 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 4 287 2.7E-111 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MKLM6_RS10730 06274d8bd4174865fd5bedd01a3c11fc 293 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 38 55 - T 28-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MKLM6_RS10730 06274d8bd4174865fd5bedd01a3c11fc 293 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 133 163 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 MKLM6_RS10730 06274d8bd4174865fd5bedd01a3c11fc 293 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 287 66.166 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MKLM6_RS10730 06274d8bd4174865fd5bedd01a3c11fc 293 Gene3D G3DSA:3.20.20.70 1 293 9.6E-100 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS10730 06274d8bd4174865fd5bedd01a3c11fc 293 SUPERFAMILY SSF51569 1 291 9.52E-103 T 28-03-2018 MKLM6_RS10730 06274d8bd4174865fd5bedd01a3c11fc 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 3.1E-35 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MKLM6_RS10730 06274d8bd4174865fd5bedd01a3c11fc 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 3.1E-35 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MKLM6_RS10730 06274d8bd4174865fd5bedd01a3c11fc 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 3.1E-35 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MKLM6_RS10730 06274d8bd4174865fd5bedd01a3c11fc 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 3.1E-35 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MKLM6_RS20750 c37dde9c9c2d2b40b40e22490210c32a 155 Gene3D G3DSA:3.10.20.30 2 73 9.6E-24 T 28-03-2018 IPR012675 Beta-grasp domain MKLM6_RS20750 c37dde9c9c2d2b40b40e22490210c32a 155 Gene3D G3DSA:1.10.150.120 74 155 2.9E-28 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 MKLM6_RS20750 c37dde9c9c2d2b40b40e22490210c32a 155 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 62 1.5E-6 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MKLM6_RS20750 c37dde9c9c2d2b40b40e22490210c32a 155 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MKLM6_RS20750 c37dde9c9c2d2b40b40e22490210c32a 155 SUPERFAMILY SSF54292 4 77 3.41E-24 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MKLM6_RS20750 c37dde9c9c2d2b40b40e22490210c32a 155 SUPERFAMILY SSF47741 83 151 2.22E-28 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 MKLM6_RS20750 c37dde9c9c2d2b40b40e22490210c32a 155 Pfam PF01799 [2Fe-2S] binding domain 72 145 5.8E-26 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 MKLM6_RS16310 7d20a3e0e626a31d70ec9901259ace71 804 SUPERFAMILY SSF52540 416 560 1.31E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS16310 7d20a3e0e626a31d70ec9901259ace71 804 SUPERFAMILY SSF52540 186 334 1.31E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS16310 7d20a3e0e626a31d70ec9901259ace71 804 SMART SM00487 162 362 1.6E-16 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MKLM6_RS16310 7d20a3e0e626a31d70ec9901259ace71 804 Gene3D G3DSA:3.40.50.300 153 347 4.0E-23 T 28-03-2018 MKLM6_RS16310 7d20a3e0e626a31d70ec9901259ace71 804 Gene3D G3DSA:3.40.50.300 429 594 7.5E-13 T 28-03-2018 MKLM6_RS16310 7d20a3e0e626a31d70ec9901259ace71 804 Pfam PF00271 Helicase conserved C-terminal domain 441 557 4.2E-7 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS16310 7d20a3e0e626a31d70ec9901259ace71 804 Pfam PF04851 Type III restriction enzyme, res subunit 166 332 4.4E-29 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MKLM6_RS03035 ffc050c1913360cfaf6d15691d7167d9 430 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 6 422 4.4E-195 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MKLM6_RS03035 ffc050c1913360cfaf6d15691d7167d9 430 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 5 141 4.4E-73 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MKLM6_RS03035 ffc050c1913360cfaf6d15691d7167d9 430 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 77 91 - T 28-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MKLM6_RS03035 ffc050c1913360cfaf6d15691d7167d9 430 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 191 350 1.2E-83 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MKLM6_RS03035 ffc050c1913360cfaf6d15691d7167d9 430 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 1 422 49.114 T 28-03-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508 MKLM6_RS03035 ffc050c1913360cfaf6d15691d7167d9 430 SMART SM00996 5 429 0.0 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MKLM6_RS03035 ffc050c1913360cfaf6d15691d7167d9 430 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 213 229 - T 28-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MKLM6_RS03035 ffc050c1913360cfaf6d15691d7167d9 430 Gene3D G3DSA:3.40.50.1480 208 403 2.1E-86 T 28-03-2018 MKLM6_RS03035 ffc050c1913360cfaf6d15691d7167d9 430 Gene3D G3DSA:3.40.50.1480 145 207 5.3E-12 T 28-03-2018 MKLM6_RS03035 ffc050c1913360cfaf6d15691d7167d9 430 SUPERFAMILY SSF52283 2 190 1.42E-118 T 28-03-2018 MKLM6_RS03035 ffc050c1913360cfaf6d15691d7167d9 430 SUPERFAMILY SSF52283 351 430 1.42E-118 T 28-03-2018 MKLM6_RS03035 ffc050c1913360cfaf6d15691d7167d9 430 SUPERFAMILY SSF51735 191 350 4.23E-81 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS03035 ffc050c1913360cfaf6d15691d7167d9 430 PIRSF PIRSF001109 1 430 1.3E-198 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MKLM6_RS03035 ffc050c1913360cfaf6d15691d7167d9 430 Gene3D G3DSA:3.40.50.1480 1 144 3.6E-73 T 28-03-2018 MKLM6_RS03035 ffc050c1913360cfaf6d15691d7167d9 430 SMART SM00997 191 350 9.5E-116 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MKLM6_RS19880 fe621e2e7c04b3827454db8f7d7fdbb9 270 PIRSF PIRSF003092 1 270 2.0E-92 T 28-03-2018 IPR025501 ATP binding protein MinD MKLM6_RS19880 fe621e2e7c04b3827454db8f7d7fdbb9 270 Gene3D G3DSA:3.40.50.300 1 259 4.0E-54 T 28-03-2018 MKLM6_RS19880 fe621e2e7c04b3827454db8f7d7fdbb9 270 Pfam PF13614 AAA domain 3 159 7.6E-20 T 28-03-2018 IPR025669 AAA domain MKLM6_RS19880 fe621e2e7c04b3827454db8f7d7fdbb9 270 SUPERFAMILY SSF52540 2 268 1.35E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS19880 fe621e2e7c04b3827454db8f7d7fdbb9 270 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 2 268 3.9E-110 T 28-03-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 MKLM6_RS20540 804117669a9666436424dbb8b4949100 316 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 15 307 2.5E-99 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS20540 804117669a9666436424dbb8b4949100 316 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 73 84 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS20540 804117669a9666436424dbb8b4949100 316 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 251 279 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS20540 804117669a9666436424dbb8b4949100 316 Pfam PF07478 D-ala D-ala ligase C-terminus 114 306 1.2E-54 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS20540 804117669a9666436424dbb8b4949100 316 SUPERFAMILY SSF52440 14 106 6.43E-27 T 28-03-2018 IPR016185 Pre-ATP-grasp domain MKLM6_RS20540 804117669a9666436424dbb8b4949100 316 Gene3D G3DSA:3.40.50.20 7 107 4.8E-28 T 28-03-2018 MKLM6_RS20540 804117669a9666436424dbb8b4949100 316 Gene3D G3DSA:3.30.1490.20 108 175 2.4E-22 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MKLM6_RS20540 804117669a9666436424dbb8b4949100 316 Pfam PF01820 D-ala D-ala ligase N-terminus 14 96 1.2E-15 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS20540 804117669a9666436424dbb8b4949100 316 PIRSF PIRSF039102 51 314 9.8E-84 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS20540 804117669a9666436424dbb8b4949100 316 PIRSF PIRSF039102 11 58 6.2E-7 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS20540 804117669a9666436424dbb8b4949100 316 SUPERFAMILY SSF56059 107 305 1.23E-57 T 28-03-2018 MKLM6_RS20540 804117669a9666436424dbb8b4949100 316 Gene3D G3DSA:3.30.470.20 176 314 1.0E-36 T 28-03-2018 MKLM6_RS20540 804117669a9666436424dbb8b4949100 316 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 13 309 33.57 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS07760 141d082eddbbb1883e9e51b9ca63f469 853 Gene3D G3DSA:1.10.150.200 305 371 0.0021 T 28-03-2018 MKLM6_RS07760 141d082eddbbb1883e9e51b9ca63f469 853 Gene3D G3DSA:1.10.150.200 220 265 7.0E-9 T 28-03-2018 MKLM6_RS07760 141d082eddbbb1883e9e51b9ca63f469 853 Gene3D G3DSA:1.10.150.200 40 99 8.0E-16 T 28-03-2018 MKLM6_RS07760 141d082eddbbb1883e9e51b9ca63f469 853 Gene3D G3DSA:1.10.150.200 266 304 5.5E-10 T 28-03-2018 MKLM6_RS07760 141d082eddbbb1883e9e51b9ca63f469 853 Gene3D G3DSA:3.40.50.1460 546 852 1.4E-34 T 28-03-2018 MKLM6_RS07760 141d082eddbbb1883e9e51b9ca63f469 853 SUPERFAMILY SSF48452 12 168 2.85E-22 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS07760 141d082eddbbb1883e9e51b9ca63f469 853 Pfam PF13374 Tetratricopeptide repeat 134 165 1.3E-5 T 28-03-2018 MKLM6_RS07760 141d082eddbbb1883e9e51b9ca63f469 853 Pfam PF13424 Tetratricopeptide repeat 258 327 2.0E-12 T 28-03-2018 MKLM6_RS07760 141d082eddbbb1883e9e51b9ca63f469 853 Pfam PF13424 Tetratricopeptide repeat 174 247 2.9E-13 T 28-03-2018 MKLM6_RS07760 141d082eddbbb1883e9e51b9ca63f469 853 Pfam PF13424 Tetratricopeptide repeat 51 120 3.5E-17 T 28-03-2018 MKLM6_RS07760 141d082eddbbb1883e9e51b9ca63f469 853 Pfam PF12770 CHAT domain 558 851 6.5E-55 T 28-03-2018 IPR024983 CHAT domain MKLM6_RS07760 141d082eddbbb1883e9e51b9ca63f469 853 SUPERFAMILY SSF48452 173 374 2.09E-30 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS07760 141d082eddbbb1883e9e51b9ca63f469 853 Gene3D G3DSA:3.30.70.100 136 172 2.7E-7 T 28-03-2018 MKLM6_RS07760 141d082eddbbb1883e9e51b9ca63f469 853 Gene3D G3DSA:3.30.70.100 173 219 1.2E-13 T 28-03-2018 MKLM6_RS07760 141d082eddbbb1883e9e51b9ca63f469 853 SMART SM00028 256 289 2.6 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS07760 141d082eddbbb1883e9e51b9ca63f469 853 SMART SM00028 176 209 8.4E-5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS07760 141d082eddbbb1883e9e51b9ca63f469 853 SMART SM00028 51 84 0.0024 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS07760 141d082eddbbb1883e9e51b9ca63f469 853 SMART SM00028 296 329 11.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS07760 141d082eddbbb1883e9e51b9ca63f469 853 SMART SM00028 91 124 1.5E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS07760 141d082eddbbb1883e9e51b9ca63f469 853 SMART SM00028 133 166 16.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS07760 141d082eddbbb1883e9e51b9ca63f469 853 SMART SM00028 216 249 9.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS07760 141d082eddbbb1883e9e51b9ca63f469 853 SMART SM00028 12 45 6.7 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS07760 141d082eddbbb1883e9e51b9ca63f469 853 Gene3D G3DSA:1.25.40.10 100 135 3.2E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS02070 41c4f43c0b73808cbc2f33bf977f6eb1 447 SMART SM00100 147 266 6.9E-19 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain MKLM6_RS02070 41c4f43c0b73808cbc2f33bf977f6eb1 447 Gene3D G3DSA:1.20.5.400 378 443 4.4E-5 T 28-03-2018 MKLM6_RS02070 41c4f43c0b73808cbc2f33bf977f6eb1 447 SUPERFAMILY SSF51206 134 253 5.37E-30 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like MKLM6_RS02070 41c4f43c0b73808cbc2f33bf977f6eb1 447 PRINTS PR00103 cAMP-dependent protein kinase signature 183 197 1.5E-7 T 28-03-2018 MKLM6_RS02070 41c4f43c0b73808cbc2f33bf977f6eb1 447 PRINTS PR00103 cAMP-dependent protein kinase signature 214 223 1.5E-7 T 28-03-2018 MKLM6_RS02070 41c4f43c0b73808cbc2f33bf977f6eb1 447 PRINTS PR00103 cAMP-dependent protein kinase signature 168 182 1.5E-7 T 28-03-2018 MKLM6_RS02070 41c4f43c0b73808cbc2f33bf977f6eb1 447 PRINTS PR00103 cAMP-dependent protein kinase signature 226 237 1.5E-7 T 28-03-2018 MKLM6_RS02070 41c4f43c0b73808cbc2f33bf977f6eb1 447 SMART SM00450 259 352 1.4E-6 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS02070 41c4f43c0b73808cbc2f33bf977f6eb1 447 Gene3D G3DSA:2.60.120.10 129 262 1.5E-30 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS02070 41c4f43c0b73808cbc2f33bf977f6eb1 447 Gene3D G3DSA:3.40.250.10 263 352 1.1E-19 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS02070 41c4f43c0b73808cbc2f33bf977f6eb1 447 SUPERFAMILY SSF52821 244 346 1.96E-21 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS02070 41c4f43c0b73808cbc2f33bf977f6eb1 447 SUPERFAMILY SSF51206 12 118 2.75E-10 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like MKLM6_RS02070 41c4f43c0b73808cbc2f33bf977f6eb1 447 Gene3D G3DSA:2.60.120.10 4 127 8.5E-9 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS02070 41c4f43c0b73808cbc2f33bf977f6eb1 447 Pfam PF00581 Rhodanese-like domain 263 346 2.1E-10 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS02070 41c4f43c0b73808cbc2f33bf977f6eb1 447 Pfam PF00027 Cyclic nucleotide-binding domain 167 253 1.1E-20 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain MKLM6_RS19250 64da07375456ed365a35cf2ac439dba0 91 SUPERFAMILY SSF143011 1 91 6.93E-16 T 28-03-2018 IPR035095 Toxin RelE-like domain MKLM6_RS19250 64da07375456ed365a35cf2ac439dba0 91 Gene3D G3DSA:3.30.2310.20 1 91 6.0E-19 T 28-03-2018 MKLM6_RS12545 2e8dbef0d05767ddd36fb3403c8d7113 394 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MKLM6_RS12545 2e8dbef0d05767ddd36fb3403c8d7113 394 Gene3D G3DSA:3.90.1170.30 66 91 0.26 T 28-03-2018 MKLM6_RS12545 2e8dbef0d05767ddd36fb3403c8d7113 394 SUPERFAMILY SSF47005 88 132 2.09E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MKLM6_RS12545 2e8dbef0d05767ddd36fb3403c8d7113 394 Gene3D G3DSA:3.30.559.10 149 392 3.7E-89 T 28-03-2018 MKLM6_RS12545 2e8dbef0d05767ddd36fb3403c8d7113 394 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 165 391 3.2E-81 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MKLM6_RS12545 2e8dbef0d05767ddd36fb3403c8d7113 394 Pfam PF02817 e3 binding domain 94 128 1.4E-13 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MKLM6_RS12545 2e8dbef0d05767ddd36fb3403c8d7113 394 SUPERFAMILY SSF51230 1 93 2.22E-24 T 28-03-2018 IPR011053 Single hybrid motif MKLM6_RS12545 2e8dbef0d05767ddd36fb3403c8d7113 394 SUPERFAMILY SSF52777 164 393 3.91E-88 T 28-03-2018 MKLM6_RS12545 2e8dbef0d05767ddd36fb3403c8d7113 394 Gene3D G3DSA:4.10.320.10 92 148 4.4E-18 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MKLM6_RS12545 2e8dbef0d05767ddd36fb3403c8d7113 394 Gene3D G3DSA:2.40.50.100 2 65 6.0E-12 T 28-03-2018 MKLM6_RS12545 2e8dbef0d05767ddd36fb3403c8d7113 394 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 4 393 4.2E-163 T 28-03-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 MKLM6_RS12545 2e8dbef0d05767ddd36fb3403c8d7113 394 Pfam PF00364 Biotin-requiring enzyme 5 76 6.4E-18 T 28-03-2018 IPR000089 Biotin/lipoyl attachment MKLM6_RS12960 efc833948db3ec22792212948aad09da 249 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS12960 efc833948db3ec22792212948aad09da 249 Pfam PF00005 ABC transporter 17 172 1.6E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS12960 efc833948db3ec22792212948aad09da 249 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 244 1.4E-109 T 28-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 MKLM6_RS12960 efc833948db3ec22792212948aad09da 249 SMART SM00382 26 230 0.0029 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS12960 efc833948db3ec22792212948aad09da 249 Gene3D G3DSA:3.40.50.300 1 249 3.6E-44 T 28-03-2018 MKLM6_RS12960 efc833948db3ec22792212948aad09da 249 SUPERFAMILY SSF52540 2 231 3.59E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS14130 47b1a7ad46a74039dabf2b938ab9e37e 332 Pfam PF01966 HD domain 153 273 5.0E-18 T 28-03-2018 IPR006674 HD domain MKLM6_RS14130 47b1a7ad46a74039dabf2b938ab9e37e 332 SUPERFAMILY SSF109604 141 314 2.1E-41 T 28-03-2018 MKLM6_RS14130 47b1a7ad46a74039dabf2b938ab9e37e 332 Pfam PF00072 Response regulator receiver domain 6 116 6.3E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14130 47b1a7ad46a74039dabf2b938ab9e37e 332 SMART SM00448 4 116 5.3E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14130 47b1a7ad46a74039dabf2b938ab9e37e 332 Gene3D G3DSA:3.40.50.2300 5 123 9.8E-33 T 28-03-2018 MKLM6_RS14130 47b1a7ad46a74039dabf2b938ab9e37e 332 Gene3D G3DSA:1.10.3210.10 124 323 2.2E-50 T 28-03-2018 MKLM6_RS14130 47b1a7ad46a74039dabf2b938ab9e37e 332 SMART SM00471 146 283 3.2E-6 T 28-03-2018 IPR003607 HD/PDEase domain MKLM6_RS14130 47b1a7ad46a74039dabf2b938ab9e37e 332 SUPERFAMILY SSF52172 5 124 4.27E-37 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS19800 2c554c091c16dfbd01d401036e93a2a9 155 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 7 148 44.998 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 MKLM6_RS19800 2c554c091c16dfbd01d401036e93a2a9 155 SUPERFAMILY SSF53927 2 152 9.03E-54 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 MKLM6_RS19800 2c554c091c16dfbd01d401036e93a2a9 155 Pfam PF14437 MafB19-like deaminase 2 148 1.5E-28 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 MKLM6_RS19800 2c554c091c16dfbd01d401036e93a2a9 155 Gene3D G3DSA:3.40.140.10 1 155 1.6E-48 T 28-03-2018 MKLM6_RS19800 2c554c091c16dfbd01d401036e93a2a9 155 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 52 89 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MKLM6_RS14750 85571dc305104718606824c16d2505d2 115 Pfam PF07883 Cupin domain 50 105 6.0E-7 T 28-03-2018 IPR013096 Cupin 2, conserved barrel MKLM6_RS14750 85571dc305104718606824c16d2505d2 115 Gene3D G3DSA:2.60.120.10 18 110 4.3E-15 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS14750 85571dc305104718606824c16d2505d2 115 SUPERFAMILY SSF51182 8 109 1.38E-15 T 28-03-2018 IPR011051 RmlC-like cupin domain MKLM6_RS18825 c76eb5dd85b79b662544bebb1ce40036 559 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 6 327 6.2E-79 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MKLM6_RS18825 c76eb5dd85b79b662544bebb1ce40036 559 PRINTS PR01005 Flagellar hook-associated protein signature 124 144 4.7E-37 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MKLM6_RS18825 c76eb5dd85b79b662544bebb1ce40036 559 PRINTS PR01005 Flagellar hook-associated protein signature 12 35 4.7E-37 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MKLM6_RS18825 c76eb5dd85b79b662544bebb1ce40036 559 PRINTS PR01005 Flagellar hook-associated protein signature 477 498 4.7E-37 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MKLM6_RS18825 c76eb5dd85b79b662544bebb1ce40036 559 PRINTS PR01005 Flagellar hook-associated protein signature 50 72 4.7E-37 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MKLM6_RS18825 c76eb5dd85b79b662544bebb1ce40036 559 PRINTS PR01005 Flagellar hook-associated protein signature 218 236 4.7E-37 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MKLM6_RS18825 c76eb5dd85b79b662544bebb1ce40036 559 PRINTS PR01005 Flagellar hook-associated protein signature 157 181 4.7E-37 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MKLM6_RS18825 c76eb5dd85b79b662544bebb1ce40036 559 PRINTS PR01005 Flagellar hook-associated protein signature 524 548 4.7E-37 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MKLM6_RS18825 c76eb5dd85b79b662544bebb1ce40036 559 PRINTS PR01005 Flagellar hook-associated protein signature 418 435 4.7E-37 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MKLM6_RS18825 c76eb5dd85b79b662544bebb1ce40036 559 SUPERFAMILY SSF64518 135 559 2.48E-33 T 28-03-2018 MKLM6_RS18825 c76eb5dd85b79b662544bebb1ce40036 559 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 12 32 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site MKLM6_RS18825 c76eb5dd85b79b662544bebb1ce40036 559 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 499 556 1.9E-10 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain MKLM6_RS18825 c76eb5dd85b79b662544bebb1ce40036 559 Pfam PF00460 Flagella basal body rod protein 8 35 4.8E-10 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 MKLM6_RS05880 d90cfeb02bec83501ee8612b9d124e31 526 SMART SM00388 299 366 7.4E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS05880 d90cfeb02bec83501ee8612b9d124e31 526 Pfam PF00672 HAMP domain 214 262 1.7E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS05880 d90cfeb02bec83501ee8612b9d124e31 526 Gene3D G3DSA:1.10.287.130 289 362 9.0E-17 T 28-03-2018 MKLM6_RS05880 d90cfeb02bec83501ee8612b9d124e31 526 Gene3D G3DSA:3.30.565.10 370 526 7.5E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS05880 d90cfeb02bec83501ee8612b9d124e31 526 SUPERFAMILY SSF55874 355 523 3.54E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS05880 d90cfeb02bec83501ee8612b9d124e31 526 SMART SM00387 412 524 2.2E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS05880 d90cfeb02bec83501ee8612b9d124e31 526 SUPERFAMILY SSF158472 214 262 4.05E-10 T 28-03-2018 MKLM6_RS05880 d90cfeb02bec83501ee8612b9d124e31 526 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 412 522 1.1E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS05880 d90cfeb02bec83501ee8612b9d124e31 526 Pfam PF00512 His Kinase A (phospho-acceptor) domain 299 365 1.3E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS05880 d90cfeb02bec83501ee8612b9d124e31 526 SMART SM00304 214 266 1.7E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS05880 d90cfeb02bec83501ee8612b9d124e31 526 PRINTS PR00344 Bacterial sensor protein C-terminal signature 508 521 5.9E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS05880 d90cfeb02bec83501ee8612b9d124e31 526 PRINTS PR00344 Bacterial sensor protein C-terminal signature 449 463 5.9E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS05880 d90cfeb02bec83501ee8612b9d124e31 526 PRINTS PR00344 Bacterial sensor protein C-terminal signature 467 477 5.9E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS05880 d90cfeb02bec83501ee8612b9d124e31 526 PRINTS PR00344 Bacterial sensor protein C-terminal signature 484 502 5.9E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS05880 d90cfeb02bec83501ee8612b9d124e31 526 SUPERFAMILY SSF47384 284 365 1.06E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS11655 a7ec422c8e80e24678d5a5798261c04d 379 Pfam PF05155 Phage X family 289 373 4.0E-24 T 28-03-2018 IPR022688 Replication-associated protein G2P, C-terminal GO:0006260 MKLM6_RS11655 a7ec422c8e80e24678d5a5798261c04d 379 Pfam PF05144 Phage replication protein CRI 54 250 2.4E-7 T 28-03-2018 IPR022686 Replication-associated protein G2P, N-terminal GO:0006260 MKLM6_RS22380 6b765c2a866075c9bfce045aabd81b83 614 TIGRFAM TIGR03743 SXT_TraD: conjugative coupling factor TraD, SXT/TOL subfamily 9 598 1.9E-201 T 28-03-2018 IPR022458 Conjugative coupling factor TraG/TraD MKLM6_RS22380 6b765c2a866075c9bfce045aabd81b83 614 Pfam PF12696 TraM recognition site of TraD and TraG 450 575 1.5E-11 T 28-03-2018 IPR032689 TraD/TraG, TraM recognition site MKLM6_RS22380 6b765c2a866075c9bfce045aabd81b83 614 Pfam PF12846 AAA-like domain 152 238 1.2E-7 T 28-03-2018 MKLM6_RS22380 6b765c2a866075c9bfce045aabd81b83 614 Gene3D G3DSA:3.40.50.300 105 607 3.4E-29 T 28-03-2018 MKLM6_RS22380 6b765c2a866075c9bfce045aabd81b83 614 SUPERFAMILY SSF52540 128 304 2.21E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS22380 6b765c2a866075c9bfce045aabd81b83 614 SUPERFAMILY SSF52540 352 592 2.21E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS12270 77f7669a485a5a1676e9278400b3370b 429 SUPERFAMILY SSF51998 17 398 4.49E-63 T 28-03-2018 MKLM6_RS12270 77f7669a485a5a1676e9278400b3370b 429 Pfam PF05167 Uncharacterised ACR (DUF711) 19 386 1.7E-64 T 28-03-2018 IPR007841 Uncharacterised protein family UPF0210 MKLM6_RS12270 77f7669a485a5a1676e9278400b3370b 429 Gene3D G3DSA:3.20.70.20 15 403 2.2E-72 T 28-03-2018 MKLM6_RS01865 9fcde9243b2720a78d59750d1e95685c 560 SUPERFAMILY SSF110296 68 242 4.97E-13 T 28-03-2018 MKLM6_RS01865 9fcde9243b2720a78d59750d1e95685c 560 SUPERFAMILY SSF110296 333 416 4.97E-13 T 28-03-2018 MKLM6_RS01865 9fcde9243b2720a78d59750d1e95685c 560 Gene3D G3DSA:2.120.10.10 307 476 1.5E-12 T 28-03-2018 MKLM6_RS01865 9fcde9243b2720a78d59750d1e95685c 560 Gene3D G3DSA:2.130.10.10 37 268 3.1E-16 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MKLM6_RS06875 a8b3a88912eb85089c07bd6f90d259a7 191 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 89 117 - T 28-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 MKLM6_RS06875 a8b3a88912eb85089c07bd6f90d259a7 191 SUPERFAMILY SSF53955 51 189 2.82E-47 T 28-03-2018 IPR023346 Lysozyme-like domain MKLM6_RS06875 a8b3a88912eb85089c07bd6f90d259a7 191 Gene3D G3DSA:1.10.530.10 38 191 1.0E-47 T 28-03-2018 MKLM6_RS06875 a8b3a88912eb85089c07bd6f90d259a7 191 Pfam PF01464 Transglycosylase SLT domain 71 171 1.4E-30 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 MKLM6_RS04420 b75f20c086db55fda58e31a3049cd5d6 222 Pfam PF14113 Type VI secretion system (T6SS), amidase effector protein 4 79 219 1.8E-28 T 28-03-2018 IPR025562 Type VI secretion system (T6SS), amidase effector protein 4 MKLM6_RS21150 7517b68581b8a80be5180c6e01e33f36 263 PRINTS PR01217 Proline rich extensin signature 113 129 4.4E-9 T 28-03-2018 MKLM6_RS21150 7517b68581b8a80be5180c6e01e33f36 263 PRINTS PR01217 Proline rich extensin signature 143 160 4.4E-9 T 28-03-2018 MKLM6_RS21150 7517b68581b8a80be5180c6e01e33f36 263 PRINTS PR01217 Proline rich extensin signature 92 113 4.4E-9 T 28-03-2018 MKLM6_RS21150 7517b68581b8a80be5180c6e01e33f36 263 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 185 261 1.2E-20 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 MKLM6_RS21150 7517b68581b8a80be5180c6e01e33f36 263 Gene3D G3DSA:3.30.1150.10 86 263 3.6E-19 T 28-03-2018 MKLM6_RS21150 7517b68581b8a80be5180c6e01e33f36 263 SUPERFAMILY SSF74653 180 259 1.83E-22 T 28-03-2018 MKLM6_RS21150 7517b68581b8a80be5180c6e01e33f36 263 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 183 261 4.0E-22 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 MKLM6_RS20815 ab178b9cb36e111643be3eaedd92856a 279 Gene3D G3DSA:3.40.50.150 83 276 5.6E-49 T 28-03-2018 MKLM6_RS20815 ab178b9cb36e111643be3eaedd92856a 279 SUPERFAMILY SSF53335 84 273 5.68E-53 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS20815 ab178b9cb36e111643be3eaedd92856a 279 PRINTS PR00996 Glutamate methyltransferase family signature 145 161 2.8E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS20815 ab178b9cb36e111643be3eaedd92856a 279 PRINTS PR00996 Glutamate methyltransferase family signature 235 258 2.8E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS20815 ab178b9cb36e111643be3eaedd92856a 279 PRINTS PR00996 Glutamate methyltransferase family signature 77 89 2.8E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS20815 ab178b9cb36e111643be3eaedd92856a 279 PRINTS PR00996 Glutamate methyltransferase family signature 113 133 2.8E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS20815 ab178b9cb36e111643be3eaedd92856a 279 PRINTS PR00996 Glutamate methyltransferase family signature 38 51 2.8E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS20815 ab178b9cb36e111643be3eaedd92856a 279 PRINTS PR00996 Glutamate methyltransferase family signature 216 230 2.8E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS20815 ab178b9cb36e111643be3eaedd92856a 279 PIRSF PIRSF000410 1 277 6.8E-95 T 28-03-2018 IPR026024 Chemotaxis protein methyltransferase CheR MKLM6_RS20815 ab178b9cb36e111643be3eaedd92856a 279 Gene3D G3DSA:1.10.155.10 9 82 3.1E-15 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MKLM6_RS20815 ab178b9cb36e111643be3eaedd92856a 279 Pfam PF01739 CheR methyltransferase, SAM binding domain 84 268 1.2E-55 T 28-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal MKLM6_RS20815 ab178b9cb36e111643be3eaedd92856a 279 Pfam PF03705 CheR methyltransferase, all-alpha domain 18 64 4.0E-17 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MKLM6_RS20815 ab178b9cb36e111643be3eaedd92856a 279 SMART SM00138 16 276 1.0E-83 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS20815 ab178b9cb36e111643be3eaedd92856a 279 SUPERFAMILY SSF47757 12 83 4.18E-17 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MKLM6_RS03210 5a919102ad0a2e3158b908f530c7eab6 516 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 6 470 19.751 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MKLM6_RS03210 5a919102ad0a2e3158b908f530c7eab6 516 Pfam PF03023 MviN-like protein 31 465 9.7E-129 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MKLM6_RS03210 5a919102ad0a2e3158b908f530c7eab6 516 PIRSF PIRSF002869 2 513 3.5E-153 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MKLM6_RS03210 5a919102ad0a2e3158b908f530c7eab6 516 PRINTS PR01806 Virulence factor MviN signature 360 379 1.2E-76 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MKLM6_RS03210 5a919102ad0a2e3158b908f530c7eab6 516 PRINTS PR01806 Virulence factor MviN signature 55 71 1.2E-76 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MKLM6_RS03210 5a919102ad0a2e3158b908f530c7eab6 516 PRINTS PR01806 Virulence factor MviN signature 136 160 1.2E-76 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MKLM6_RS03210 5a919102ad0a2e3158b908f530c7eab6 516 PRINTS PR01806 Virulence factor MviN signature 160 181 1.2E-76 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MKLM6_RS03210 5a919102ad0a2e3158b908f530c7eab6 516 PRINTS PR01806 Virulence factor MviN signature 262 288 1.2E-76 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MKLM6_RS03210 5a919102ad0a2e3158b908f530c7eab6 516 PRINTS PR01806 Virulence factor MviN signature 412 429 1.2E-76 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MKLM6_RS03210 5a919102ad0a2e3158b908f530c7eab6 516 PRINTS PR01806 Virulence factor MviN signature 36 55 1.2E-76 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MKLM6_RS03210 5a919102ad0a2e3158b908f530c7eab6 516 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 6 502 9.7E-135 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MKLM6_RS16215 35f62ce53a7885877fc9fa75d67a29f6 284 Gene3D G3DSA:3.40.50.410 45 254 3.3E-11 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS16215 35f62ce53a7885877fc9fa75d67a29f6 284 SUPERFAMILY SSF53300 74 143 8.89E-5 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS06300 b6b8d15f477541d4675de1300c83a106 318 Gene3D G3DSA:3.30.160.60 290 318 4.9E-12 T 28-03-2018 MKLM6_RS06300 b6b8d15f477541d4675de1300c83a106 318 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 18 316 3.7E-87 T 28-03-2018 IPR003770 Endolytic murein transglycosylase MKLM6_RS06300 b6b8d15f477541d4675de1300c83a106 318 Gene3D G3DSA:3.30.160.60 63 94 7.5E-5 T 28-03-2018 MKLM6_RS06300 b6b8d15f477541d4675de1300c83a106 318 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 2 318 33.189 T 28-03-2018 IPR003770 Endolytic murein transglycosylase MKLM6_RS06300 b6b8d15f477541d4675de1300c83a106 318 Pfam PF02618 YceG-like family 29 314 2.4E-86 T 28-03-2018 IPR003770 Endolytic murein transglycosylase MKLM6_RS22170 399a06c54aa85eb34d993562cd0285c9 645 Gene3D G3DSA:3.90.1530.10 1 104 7.7E-30 T 28-03-2018 MKLM6_RS22170 399a06c54aa85eb34d993562cd0285c9 645 SUPERFAMILY SSF109709 98 202 1.44E-15 T 28-03-2018 MKLM6_RS22170 399a06c54aa85eb34d993562cd0285c9 645 TIGRFAM TIGR03734 PRTRC_parB: PRTRC system ParB family protein 21 583 4.8E-125 T 28-03-2018 IPR022396 ParB-related, ThiF-related cassette, ParB MKLM6_RS22170 399a06c54aa85eb34d993562cd0285c9 645 Gene3D G3DSA:1.10.10.730 105 151 1.5E-4 T 28-03-2018 MKLM6_RS22170 399a06c54aa85eb34d993562cd0285c9 645 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 12 187 5.3E-35 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 MKLM6_RS22170 399a06c54aa85eb34d993562cd0285c9 645 SUPERFAMILY SSF110849 9 108 6.63E-24 T 28-03-2018 IPR003115 ParB/Sulfiredoxin MKLM6_RS22170 399a06c54aa85eb34d993562cd0285c9 645 Pfam PF02195 ParB-like nuclease domain 15 103 1.4E-18 T 28-03-2018 IPR003115 ParB/Sulfiredoxin MKLM6_RS22170 399a06c54aa85eb34d993562cd0285c9 645 SMART SM00470 12 104 1.4E-21 T 28-03-2018 IPR003115 ParB/Sulfiredoxin MKLM6_RS15445 06f53926b1d5a3799a9675463340a8bb 313 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 309 7.2E-102 T 28-03-2018 IPR007296 Domain of unknown function DUF403 MKLM6_RS18765 bd766cf28a7ab92bfe97fddeb9cf477f 229 Pfam PF13144 Chaperone for flagella basal body P-ring formation 28 227 1.3E-50 T 28-03-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal MKLM6_RS18765 bd766cf28a7ab92bfe97fddeb9cf477f 229 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 92 228 2.2E-35 T 28-03-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal MKLM6_RS18765 bd766cf28a7ab92bfe97fddeb9cf477f 229 SMART SM00858 104 166 4.1E-5 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 MKLM6_RS18765 bd766cf28a7ab92bfe97fddeb9cf477f 229 Gene3D G3DSA:3.90.1210.10 103 169 2.3E-10 T 28-03-2018 MKLM6_RS05395 8d15aa48cbfe05dc3d1f7409e2f0b365 406 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2 245 9.3E-39 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MKLM6_RS05395 8d15aa48cbfe05dc3d1f7409e2f0b365 406 SMART SM00825 Beta-ketoacyl synthase 4 406 5.7E-11 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MKLM6_RS05395 8d15aa48cbfe05dc3d1f7409e2f0b365 406 Gene3D G3DSA:3.40.47.10 1 257 1.9E-54 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS05395 8d15aa48cbfe05dc3d1f7409e2f0b365 406 Gene3D G3DSA:3.40.47.10 259 406 3.4E-40 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS05395 8d15aa48cbfe05dc3d1f7409e2f0b365 406 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 154 170 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site MKLM6_RS05395 8d15aa48cbfe05dc3d1f7409e2f0b365 406 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 253 362 1.8E-28 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MKLM6_RS05395 8d15aa48cbfe05dc3d1f7409e2f0b365 406 SUPERFAMILY SSF53901 2 252 4.12E-56 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS05395 8d15aa48cbfe05dc3d1f7409e2f0b365 406 SUPERFAMILY SSF53901 214 405 3.53E-63 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS20615 0132f718bcda2fe05c7f81ca6d512715 284 Gene3D G3DSA:3.40.50.720 1 169 5.2E-35 T 28-03-2018 MKLM6_RS20615 0132f718bcda2fe05c7f81ca6d512715 284 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 162 281 4.2E-31 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MKLM6_RS20615 0132f718bcda2fe05c7f81ca6d512715 284 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 28-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 MKLM6_RS20615 0132f718bcda2fe05c7f81ca6d512715 284 Gene3D G3DSA:1.10.1040.10 170 282 8.6E-30 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MKLM6_RS20615 0132f718bcda2fe05c7f81ca6d512715 284 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 159 2.1E-48 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 MKLM6_RS20615 0132f718bcda2fe05c7f81ca6d512715 284 PIRSF PIRSF000103 1 284 7.4E-74 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 MKLM6_RS20615 0132f718bcda2fe05c7f81ca6d512715 284 SUPERFAMILY SSF48179 160 281 2.38E-34 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MKLM6_RS20615 0132f718bcda2fe05c7f81ca6d512715 284 SUPERFAMILY SSF51735 1 160 5.71E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS04920 70b2f8b7593d8b231a7d4d596598316b 425 Gene3D G3DSA:3.50.50.60 120 262 1.8E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS04920 70b2f8b7593d8b231a7d4d596598316b 425 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 311 2.1E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS04920 70b2f8b7593d8b231a7d4d596598316b 425 SUPERFAMILY SSF51905 262 343 6.79E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS04920 70b2f8b7593d8b231a7d4d596598316b 425 SUPERFAMILY SSF51905 3 109 6.79E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS04920 70b2f8b7593d8b231a7d4d596598316b 425 Gene3D G3DSA:3.50.50.60 1 106 1.4E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS07710 d3c243d0b5edbdeb8394a793ec9d32e5 848 SUPERFAMILY SSF69593 651 834 2.22E-29 T 28-03-2018 MKLM6_RS07710 d3c243d0b5edbdeb8394a793ec9d32e5 848 Pfam PF00501 AMP-binding enzyme 11 420 7.1E-81 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MKLM6_RS07710 d3c243d0b5edbdeb8394a793ec9d32e5 848 SMART SM00563 668 786 6.0E-22 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MKLM6_RS07710 d3c243d0b5edbdeb8394a793ec9d32e5 848 Gene3D G3DSA:3.40.50.980 159 341 7.8E-42 T 28-03-2018 MKLM6_RS07710 d3c243d0b5edbdeb8394a793ec9d32e5 848 Gene3D G3DSA:3.40.50.980 2 158 1.4E-32 T 28-03-2018 MKLM6_RS07710 d3c243d0b5edbdeb8394a793ec9d32e5 848 ProSitePatterns PS00455 Putative AMP-binding domain signature. 153 164 - T 28-03-2018 IPR020845 AMP-binding, conserved site MKLM6_RS07710 d3c243d0b5edbdeb8394a793ec9d32e5 848 SUPERFAMILY SSF47336 543 628 6.67E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS07710 d3c243d0b5edbdeb8394a793ec9d32e5 848 Pfam PF00550 Phosphopantetheine attachment site 544 608 2.8E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS07710 d3c243d0b5edbdeb8394a793ec9d32e5 848 Gene3D G3DSA:2.30.38.10 342 413 1.7E-17 T 28-03-2018 MKLM6_RS07710 d3c243d0b5edbdeb8394a793ec9d32e5 848 SUPERFAMILY SSF56801 5 258 3.14E-107 T 28-03-2018 MKLM6_RS07710 d3c243d0b5edbdeb8394a793ec9d32e5 848 SUPERFAMILY SSF56801 290 524 3.14E-107 T 28-03-2018 MKLM6_RS07710 d3c243d0b5edbdeb8394a793ec9d32e5 848 Gene3D G3DSA:3.30.300.30 415 528 4.6E-11 T 28-03-2018 MKLM6_RS07710 d3c243d0b5edbdeb8394a793ec9d32e5 848 Gene3D G3DSA:1.10.1200.10 541 617 7.3E-11 T 28-03-2018 MKLM6_RS07710 d3c243d0b5edbdeb8394a793ec9d32e5 848 Pfam PF01553 Acyltransferase 653 784 1.5E-19 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MKLM6_RS07710 d3c243d0b5edbdeb8394a793ec9d32e5 848 Gene3D G3DSA:3.40.1130.10 637 846 8.9E-33 T 28-03-2018 MKLM6_RS00485 f82783830b5208b1e71e1fddfb347fe4 158 Pfam PF08670 MEKHLA domain 16 155 1.3E-47 T 28-03-2018 IPR013978 MEKHLA MKLM6_RS00485 f82783830b5208b1e71e1fddfb347fe4 158 Gene3D G3DSA:3.30.450.20 23 146 2.5E-5 T 28-03-2018 MKLM6_RS00485 f82783830b5208b1e71e1fddfb347fe4 158 SUPERFAMILY SSF55785 57 140 2.66E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17650 708c667020a53bb55808264b01767736 279 Gene3D G3DSA:3.10.20.10 36 122 6.4E-18 T 28-03-2018 MKLM6_RS17650 708c667020a53bb55808264b01767736 279 SUPERFAMILY SSF53927 20 271 1.44E-78 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 MKLM6_RS17650 708c667020a53bb55808264b01767736 279 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 11 272 33.319 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MKLM6_RS17650 708c667020a53bb55808264b01767736 279 PIRSF PIRSF015626 10 275 2.5E-81 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MKLM6_RS17650 708c667020a53bb55808264b01767736 279 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 29 272 1.4E-68 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MKLM6_RS17650 708c667020a53bb55808264b01767736 279 Gene3D G3DSA:3.40.140.10 137 276 1.1E-48 T 28-03-2018 MKLM6_RS17650 708c667020a53bb55808264b01767736 279 Pfam PF02634 FdhD/NarQ family 34 271 7.9E-76 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MKLM6_RS11570 2e798f3168a05979033082c3a0f338c7 408 ProSitePatterns PS01007 Transposases, Mutator family, signature. 239 263 - T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS11570 2e798f3168a05979033082c3a0f338c7 408 Pfam PF00872 Transposase, Mutator family 20 384 1.2E-119 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS00875 355eaeb5d922bc0754077cf4911496d8 637 Pfam PF01434 Peptidase family M41 382 589 5.1E-74 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 MKLM6_RS00875 355eaeb5d922bc0754077cf4911496d8 637 Gene3D G3DSA:1.10.8.60 334 410 6.3E-23 T 28-03-2018 MKLM6_RS00875 355eaeb5d922bc0754077cf4911496d8 637 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 101 590 1.6E-222 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 MKLM6_RS00875 355eaeb5d922bc0754077cf4911496d8 637 SUPERFAMILY SSF140990 403 599 7.46E-69 T 28-03-2018 MKLM6_RS00875 355eaeb5d922bc0754077cf4911496d8 637 Pfam PF06480 FtsH Extracellular 9 88 4.0E-7 T 28-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 MKLM6_RS00875 355eaeb5d922bc0754077cf4911496d8 637 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 189 321 3.5E-45 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MKLM6_RS00875 355eaeb5d922bc0754077cf4911496d8 637 SUPERFAMILY SSF52540 143 391 3.11E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS00875 355eaeb5d922bc0754077cf4911496d8 637 SMART SM00382 185 324 8.4E-25 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS00875 355eaeb5d922bc0754077cf4911496d8 637 ProSitePatterns PS00674 AAA-protein family signature. 292 310 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 MKLM6_RS00875 355eaeb5d922bc0754077cf4911496d8 637 Gene3D G3DSA:3.40.50.300 126 333 1.0E-63 T 28-03-2018 MKLM6_RS00875 355eaeb5d922bc0754077cf4911496d8 637 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 2 599 35.926 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 MKLM6_RS11275 dd62bcb55a1a7c3587608804dc143dc4 408 Pfam PF00534 Glycosyl transferases group 1 216 384 2.5E-31 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 MKLM6_RS11275 dd62bcb55a1a7c3587608804dc143dc4 408 SUPERFAMILY SSF53756 10 407 8.0E-72 T 28-03-2018 MKLM6_RS11275 dd62bcb55a1a7c3587608804dc143dc4 408 Gene3D G3DSA:3.40.50.2000 215 391 1.6E-41 T 28-03-2018 MKLM6_RS11275 dd62bcb55a1a7c3587608804dc143dc4 408 Pfam PF13439 Glycosyltransferase Family 4 19 205 2.3E-12 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MKLM6_RS11275 dd62bcb55a1a7c3587608804dc143dc4 408 Gene3D G3DSA:3.40.50.2000 2 214 4.9E-17 T 28-03-2018 MKLM6_RS22485 9d26d5b91a3f52c0eb133bac31204da8 1225 Pfam PF01464 Transglycosylase SLT domain 1111 1216 2.3E-22 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 MKLM6_RS22485 9d26d5b91a3f52c0eb133bac31204da8 1225 Pfam PF07916 TraG-like protein, N-terminal region 4 458 7.1E-92 T 28-03-2018 IPR012931 TraG-like, N-terminal MKLM6_RS22485 9d26d5b91a3f52c0eb133bac31204da8 1225 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 1127 1155 - T 28-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 MKLM6_RS22485 9d26d5b91a3f52c0eb133bac31204da8 1225 Gene3D G3DSA:1.10.530.10 1060 1225 1.6E-39 T 28-03-2018 MKLM6_RS22485 9d26d5b91a3f52c0eb133bac31204da8 1225 SUPERFAMILY SSF53955 1095 1223 4.73E-39 T 28-03-2018 IPR023346 Lysozyme-like domain MKLM6_RS04865 eab4e2ea656249e9d9274dd2abf654f0 246 PIRSF PIRSF000386 1 245 5.2E-91 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MKLM6_RS04865 eab4e2ea656249e9d9274dd2abf654f0 246 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 246 104.54 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MKLM6_RS04865 eab4e2ea656249e9d9274dd2abf654f0 246 Gene3D G3DSA:1.10.1270.20 171 246 3.7E-32 T 28-03-2018 MKLM6_RS04865 eab4e2ea656249e9d9274dd2abf654f0 246 SUPERFAMILY SSF75217 1 244 4.77E-94 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases MKLM6_RS04865 eab4e2ea656249e9d9274dd2abf654f0 246 Gene3D G3DSA:3.40.1280.10 1 170 1.6E-67 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MKLM6_RS04865 eab4e2ea656249e9d9274dd2abf654f0 246 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 222 4.3E-61 T 28-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MKLM6_RS04865 eab4e2ea656249e9d9274dd2abf654f0 246 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 234 3.1E-90 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MKLM6_RS09560 c454933535978e27650835f05c3a71b9 188 Gene3D G3DSA:3.30.450.20 47 188 4.7E-19 T 28-03-2018 MKLM6_RS09560 c454933535978e27650835f05c3a71b9 188 SMART SM00091 68 134 0.0048 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09560 c454933535978e27650835f05c3a71b9 188 SUPERFAMILY SSF55785 55 181 4.54E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09560 c454933535978e27650835f05c3a71b9 188 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 65 187 8.0E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10220 60a161afbb4128e91c35bd39a631c84f 250 SMART SM00363 9 69 2.0E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MKLM6_RS10220 60a161afbb4128e91c35bd39a631c84f 250 SUPERFAMILY SSF55174 10 101 3.39E-19 T 28-03-2018 MKLM6_RS10220 60a161afbb4128e91c35bd39a631c84f 250 SUPERFAMILY SSF55120 72 241 8.87E-41 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS10220 60a161afbb4128e91c35bd39a631c84f 250 Gene3D G3DSA:3.30.70.1560 155 223 1.3E-18 T 28-03-2018 MKLM6_RS10220 60a161afbb4128e91c35bd39a631c84f 250 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 77 226 1.1E-50 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 MKLM6_RS10220 60a161afbb4128e91c35bd39a631c84f 250 Pfam PF01479 S4 domain 9 53 1.2E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MKLM6_RS10220 60a161afbb4128e91c35bd39a631c84f 250 Pfam PF00849 RNA pseudouridylate synthase 73 201 5.1E-14 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS10220 60a161afbb4128e91c35bd39a631c84f 250 Gene3D G3DSA:3.10.290.10 3 65 1.4E-16 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MKLM6_RS10220 60a161afbb4128e91c35bd39a631c84f 250 Gene3D G3DSA:3.30.70.580 66 154 8.6E-16 T 28-03-2018 MKLM6_RS10220 60a161afbb4128e91c35bd39a631c84f 250 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 111 125 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 MKLM6_RS07075 17961e0016c2c2e544dc24ccd519e53d 188 Pfam PF07209 Protein of unknown function (DUF1415) 5 172 5.6E-67 T 28-03-2018 IPR009858 Protein of unknown function DUF1415 MKLM6_RS01770 c4464b6a82292fe3b7c095ffd1d13759 203 Gene3D G3DSA:3.40.50.300 8 76 5.6E-11 T 28-03-2018 MKLM6_RS01770 c4464b6a82292fe3b7c095ffd1d13759 203 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 8 192 1.4E-74 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 MKLM6_RS01770 c4464b6a82292fe3b7c095ffd1d13759 203 SUPERFAMILY SSF52540 10 196 3.16E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS01770 c4464b6a82292fe3b7c095ffd1d13759 203 Pfam PF01926 50S ribosome-binding GTPase 27 145 2.3E-19 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS01770 c4464b6a82292fe3b7c095ffd1d13759 203 Gene3D G3DSA:3.40.50.300 77 195 5.9E-13 T 28-03-2018 MKLM6_RS01770 c4464b6a82292fe3b7c095ffd1d13759 203 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 13 196 27.272 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 MKLM6_RS06650 2884d897e99530bddb997135c97f194c 91 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 6 76 8.1E-20 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MKLM6_RS06650 2884d897e99530bddb997135c97f194c 91 SUPERFAMILY SSF143120 6 77 1.31E-19 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MKLM6_RS06650 2884d897e99530bddb997135c97f194c 91 Gene3D G3DSA:3.40.1620.10 5 55 2.2E-13 T 28-03-2018 MKLM6_RS06650 2884d897e99530bddb997135c97f194c 91 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 9 60 1.3E-12 T 28-03-2018 MKLM6_RS06495 10161aa522519183288c70269cd8677b 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 4.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MKLM6_RS06495 10161aa522519183288c70269cd8677b 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 4.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MKLM6_RS06495 10161aa522519183288c70269cd8677b 204 Gene3D G3DSA:1.10.10.60 5 40 1.9E-14 T 28-03-2018 MKLM6_RS06495 10161aa522519183288c70269cd8677b 204 Gene3D G3DSA:1.10.357.10 72 204 3.7E-29 T 28-03-2018 MKLM6_RS06495 10161aa522519183288c70269cd8677b 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 3.2E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MKLM6_RS06495 10161aa522519183288c70269cd8677b 204 SUPERFAMILY SSF46689 8 82 3.69E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS06495 10161aa522519183288c70269cd8677b 204 SUPERFAMILY SSF48498 82 200 5.93E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MKLM6_RS06495 10161aa522519183288c70269cd8677b 204 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 153 199 4.3E-7 T 28-03-2018 MKLM6_RS06495 10161aa522519183288c70269cd8677b 204 Gene3D G3DSA:1.10.260.40 41 71 5.4E-9 T 28-03-2018 MKLM6_RS00435 2a045610360174f2d4e5dec0e64101f6 269 SUPERFAMILY SSF53213 7 249 4.45E-77 T 28-03-2018 MKLM6_RS00435 2a045610360174f2d4e5dec0e64101f6 269 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 8 246 1.8E-36 T 28-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 MKLM6_RS00435 2a045610360174f2d4e5dec0e64101f6 269 Gene3D G3DSA:3.40.830.10 2 263 1.4E-73 T 28-03-2018 MKLM6_RS00435 2a045610360174f2d4e5dec0e64101f6 269 PIRSF PIRSF006157 1 268 9.7E-83 T 28-03-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 MKLM6_RS19950 d2abd26aaf4dd2f474f38a0a4fdcb2b8 103 Pfam PF13466 STAS domain 37 93 3.1E-11 T 28-03-2018 IPR002645 STAS domain MKLM6_RS19950 d2abd26aaf4dd2f474f38a0a4fdcb2b8 103 Gene3D G3DSA:3.30.750.24 6 102 4.1E-11 T 28-03-2018 IPR002645 STAS domain MKLM6_RS19950 d2abd26aaf4dd2f474f38a0a4fdcb2b8 103 SUPERFAMILY SSF52091 13 95 5.89E-12 T 28-03-2018 IPR002645 STAS domain MKLM6_RS03485 ae3d0f73d2d3d7c622b3913b783276f7 958 Gene3D G3DSA:1.20.120.330 826 958 4.6E-36 T 28-03-2018 MKLM6_RS03485 ae3d0f73d2d3d7c622b3913b783276f7 958 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 51 292 6.4E-82 T 28-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 MKLM6_RS03485 ae3d0f73d2d3d7c622b3913b783276f7 958 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 566 818 4.6E-80 T 28-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 MKLM6_RS03485 ae3d0f73d2d3d7c622b3913b783276f7 958 SUPERFAMILY SSF81593 305 454 1.02E-38 T 28-03-2018 MKLM6_RS03485 ae3d0f73d2d3d7c622b3913b783276f7 958 Gene3D G3DSA:1.10.4050.10 2 129 6.4E-19 T 28-03-2018 MKLM6_RS03485 ae3d0f73d2d3d7c622b3913b783276f7 958 Gene3D G3DSA:1.10.4050.10 536 651 1.9E-21 T 28-03-2018 MKLM6_RS03485 ae3d0f73d2d3d7c622b3913b783276f7 958 SUPERFAMILY SSF81593 829 957 3.69E-30 T 28-03-2018 MKLM6_RS03485 ae3d0f73d2d3d7c622b3913b783276f7 958 SUPERFAMILY SSF81301 42 304 1.18E-83 T 28-03-2018 MKLM6_RS03485 ae3d0f73d2d3d7c622b3913b783276f7 958 SUPERFAMILY SSF81301 539 829 4.25E-82 T 28-03-2018 MKLM6_RS03485 ae3d0f73d2d3d7c622b3913b783276f7 958 Gene3D G3DSA:1.20.120.330 303 458 3.1E-42 T 28-03-2018 MKLM6_RS03485 ae3d0f73d2d3d7c622b3913b783276f7 958 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 45 955 19.023 T 28-03-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 MKLM6_RS03485 ae3d0f73d2d3d7c622b3913b783276f7 958 Pfam PF08335 GlnD PII-uridylyltransferase 316 454 4.0E-39 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 MKLM6_RS03485 ae3d0f73d2d3d7c622b3913b783276f7 958 Pfam PF08335 GlnD PII-uridylyltransferase 840 927 7.9E-10 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 MKLM6_RS03485 ae3d0f73d2d3d7c622b3913b783276f7 958 Gene3D G3DSA:3.30.460.10 652 825 1.2E-52 T 28-03-2018 MKLM6_RS03485 ae3d0f73d2d3d7c622b3913b783276f7 958 Gene3D G3DSA:3.30.460.10 131 302 1.6E-58 T 28-03-2018 MKLM6_RS11935 349946b4ac8673b46f447356279db12d 256 Gene3D G3DSA:3.40.50.300 71 256 4.2E-28 T 28-03-2018 MKLM6_RS11935 349946b4ac8673b46f447356279db12d 256 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 54 247 3.4E-32 T 28-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 MKLM6_RS11935 349946b4ac8673b46f447356279db12d 256 Pfam PF13614 AAA domain 73 198 1.1E-8 T 28-03-2018 IPR025669 AAA domain MKLM6_RS11935 349946b4ac8673b46f447356279db12d 256 SUPERFAMILY SSF52540 73 246 5.76E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS22125 7904c0b2d5f276b7ac7d1984099e4f37 51 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.6E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS22125 7904c0b2d5f276b7ac7d1984099e4f37 51 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.6E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS22125 7904c0b2d5f276b7ac7d1984099e4f37 51 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.6E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS22125 7904c0b2d5f276b7ac7d1984099e4f37 51 SUPERFAMILY SSF46785 2 50 7.86E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS22125 7904c0b2d5f276b7ac7d1984099e4f37 51 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 50 7.0E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS22125 7904c0b2d5f276b7ac7d1984099e4f37 51 Gene3D G3DSA:1.10.10.10 1 51 3.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS13420 af56661ffc9dea4685a6d55d6755649b 406 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 152 168 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site MKLM6_RS13420 af56661ffc9dea4685a6d55d6755649b 406 SMART SM00825 Beta-ketoacyl synthase 4 406 6.1E-11 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MKLM6_RS13420 af56661ffc9dea4685a6d55d6755649b 406 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2 244 8.9E-39 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MKLM6_RS13420 af56661ffc9dea4685a6d55d6755649b 406 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 252 360 3.3E-28 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MKLM6_RS13420 af56661ffc9dea4685a6d55d6755649b 406 Gene3D G3DSA:3.40.47.10 258 404 9.8E-39 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS13420 af56661ffc9dea4685a6d55d6755649b 406 SUPERFAMILY SSF53901 213 404 6.17E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS13420 af56661ffc9dea4685a6d55d6755649b 406 Gene3D G3DSA:3.40.47.10 4 257 1.2E-56 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS13420 af56661ffc9dea4685a6d55d6755649b 406 SUPERFAMILY SSF53901 1 251 2.0E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS13530 45cc6b202e786e6894a372263f6d6f94 184 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 4 181 2.7E-53 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 MKLM6_RS13530 45cc6b202e786e6894a372263f6d6f94 184 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 49 71 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MKLM6_RS13530 45cc6b202e786e6894a372263f6d6f94 184 PIRSF PIRSF000847 1 184 1.8E-44 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 MKLM6_RS13530 45cc6b202e786e6894a372263f6d6f94 184 Pfam PF01066 CDP-alcohol phosphatidyltransferase 5 71 6.1E-16 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MKLM6_RS16235 365ef5818b86b062aa31db5c08dd7a82 158 TIGRFAM TIGR03872 cytochrome_MoxG: cytochrome c(L), periplasmic 27 158 7.2E-63 T 28-03-2018 IPR009153 Cytochrome cL GO:0005506|GO:0009055|GO:0020037|GO:0042597 MKLM6_RS16235 365ef5818b86b062aa31db5c08dd7a82 158 PIRSF PIRSF000008 1 158 2.0E-61 T 28-03-2018 IPR009153 Cytochrome cL GO:0005506|GO:0009055|GO:0020037|GO:0042597 MKLM6_RS16235 365ef5818b86b062aa31db5c08dd7a82 158 SUPERFAMILY SSF46626 5 157 3.62E-26 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS16235 365ef5818b86b062aa31db5c08dd7a82 158 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 68 143 6.3E-9 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS16235 365ef5818b86b062aa31db5c08dd7a82 158 Gene3D G3DSA:1.10.760.10 40 158 4.1E-23 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS19450 d10d978b7898f67aa5ceb6c1592be7c8 1148 SMART SM00487 599 788 4.1E-36 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MKLM6_RS19450 d10d978b7898f67aa5ceb6c1592be7c8 1148 SUPERFAMILY SSF52540 522 783 1.07E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS19450 d10d978b7898f67aa5ceb6c1592be7c8 1148 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 30 1109 28.274 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 MKLM6_RS19450 d10d978b7898f67aa5ceb6c1592be7c8 1148 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 150 1081 0.0 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 MKLM6_RS19450 d10d978b7898f67aa5ceb6c1592be7c8 1148 SUPERFAMILY SSF52540 352 463 1.86E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS19450 d10d978b7898f67aa5ceb6c1592be7c8 1148 Pfam PF00271 Helicase conserved C-terminal domain 807 908 1.2E-15 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS19450 d10d978b7898f67aa5ceb6c1592be7c8 1148 SUPERFAMILY SSF143517 993 1145 1.83E-40 T 28-03-2018 MKLM6_RS19450 d10d978b7898f67aa5ceb6c1592be7c8 1148 SUPERFAMILY SSF52540 11 344 1.04E-98 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS19450 d10d978b7898f67aa5ceb6c1592be7c8 1148 SUPERFAMILY SSF52540 781 989 2.48E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS19450 d10d978b7898f67aa5ceb6c1592be7c8 1148 Pfam PF03461 TRCF domain 1008 1099 7.7E-27 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 MKLM6_RS19450 d10d978b7898f67aa5ceb6c1592be7c8 1148 SMART SM00982 1007 1107 4.3E-45 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 MKLM6_RS19450 d10d978b7898f67aa5ceb6c1592be7c8 1148 Pfam PF02559 CarD-like/TRCF domain 479 572 5.7E-24 T 28-03-2018 IPR003711 CarD-like/TRCF domain MKLM6_RS19450 d10d978b7898f67aa5ceb6c1592be7c8 1148 Pfam PF00270 DEAD/DEAH box helicase 604 763 1.3E-19 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MKLM6_RS19450 d10d978b7898f67aa5ceb6c1592be7c8 1148 SMART SM01058 478 575 4.4E-47 T 28-03-2018 IPR003711 CarD-like/TRCF domain MKLM6_RS19450 d10d978b7898f67aa5ceb6c1592be7c8 1148 Gene3D G3DSA:3.40.50.300 788 955 6.3E-23 T 28-03-2018 MKLM6_RS19450 d10d978b7898f67aa5ceb6c1592be7c8 1148 SUPERFAMILY SSF141259 472 547 3.14E-23 T 28-03-2018 IPR003711 CarD-like/TRCF domain MKLM6_RS19450 d10d978b7898f67aa5ceb6c1592be7c8 1148 SMART SM00490 825 909 8.0E-16 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS19450 d10d978b7898f67aa5ceb6c1592be7c8 1148 Gene3D G3DSA:3.40.50.300 437 780 1.1E-39 T 28-03-2018 MKLM6_RS02410 0ce7a9d1fcc1d6a092b789a080dd672d 443 Gene3D G3DSA:1.20.1600.10 18 432 7.1E-63 T 28-03-2018 MKLM6_RS02410 0ce7a9d1fcc1d6a092b789a080dd672d 443 SUPERFAMILY SSF56954 4 430 1.57E-71 T 28-03-2018 MKLM6_RS02410 0ce7a9d1fcc1d6a092b789a080dd672d 443 Pfam PF02321 Outer membrane efflux protein 32 222 1.8E-21 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS02410 0ce7a9d1fcc1d6a092b789a080dd672d 443 Pfam PF02321 Outer membrane efflux protein 251 428 4.2E-24 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS15895 c4ec7a503a96a610b3f1362a5eee24eb 227 PRINTS PR00344 Bacterial sensor protein C-terminal signature 184 202 1.9E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS15895 c4ec7a503a96a610b3f1362a5eee24eb 227 PRINTS PR00344 Bacterial sensor protein C-terminal signature 153 167 1.9E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS15895 c4ec7a503a96a610b3f1362a5eee24eb 227 PRINTS PR00344 Bacterial sensor protein C-terminal signature 214 227 1.9E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS15895 c4ec7a503a96a610b3f1362a5eee24eb 227 Gene3D G3DSA:3.30.565.10 18 227 2.9E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS15895 c4ec7a503a96a610b3f1362a5eee24eb 227 SUPERFAMILY SSF55874 82 227 5.63E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS08715 5e0f7e353509c1a85a7a34ac2d7f8865 247 Pfam PF02104 SURF1 family 23 230 1.9E-32 T 28-03-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS05990 ffa6b0f16923ac739afd25b3ceb0ed97 683 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 128 253 6.9E-20 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05990 ffa6b0f16923ac739afd25b3ceb0ed97 683 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 16 125 3.5E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05990 ffa6b0f16923ac739afd25b3ceb0ed97 683 SMART SM00091 131 197 0.0013 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05990 ffa6b0f16923ac739afd25b3ceb0ed97 683 SMART SM00091 1 71 5.0 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05990 ffa6b0f16923ac739afd25b3ceb0ed97 683 SMART SM00086 77 119 1.2E-6 T 28-03-2018 IPR001610 PAC motif MKLM6_RS05990 ffa6b0f16923ac739afd25b3ceb0ed97 683 SMART SM00086 205 247 1.4E-7 T 28-03-2018 IPR001610 PAC motif MKLM6_RS05990 ffa6b0f16923ac739afd25b3ceb0ed97 683 SMART SM00052 429 675 5.4E-121 T 28-03-2018 IPR001633 EAL domain MKLM6_RS05990 ffa6b0f16923ac739afd25b3ceb0ed97 683 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 254 417 2.7E-43 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS05990 ffa6b0f16923ac739afd25b3ceb0ed97 683 SUPERFAMILY SSF55785 116 245 5.76E-23 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05990 ffa6b0f16923ac739afd25b3ceb0ed97 683 SMART SM00267 247 419 1.0E-59 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS05990 ffa6b0f16923ac739afd25b3ceb0ed97 683 Gene3D G3DSA:3.30.70.270 260 427 5.0E-60 T 28-03-2018 MKLM6_RS05990 ffa6b0f16923ac739afd25b3ceb0ed97 683 SUPERFAMILY SSF141868 436 682 3.92E-89 T 28-03-2018 IPR001633 EAL domain MKLM6_RS05990 ffa6b0f16923ac739afd25b3ceb0ed97 683 Pfam PF00990 Diguanylate cyclase, GGDEF domain 258 415 1.0E-48 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS05990 ffa6b0f16923ac739afd25b3ceb0ed97 683 Gene3D G3DSA:3.20.20.450 428 683 3.9E-99 T 28-03-2018 IPR001633 EAL domain MKLM6_RS05990 ffa6b0f16923ac739afd25b3ceb0ed97 683 Pfam PF08447 PAS fold 25 112 4.5E-18 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS05990 ffa6b0f16923ac739afd25b3ceb0ed97 683 SUPERFAMILY SSF55073 263 420 1.65E-50 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS05990 ffa6b0f16923ac739afd25b3ceb0ed97 683 SUPERFAMILY SSF55785 15 121 5.48E-22 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05990 ffa6b0f16923ac739afd25b3ceb0ed97 683 Gene3D G3DSA:3.30.450.20 3 125 2.1E-25 T 28-03-2018 MKLM6_RS05990 ffa6b0f16923ac739afd25b3ceb0ed97 683 Pfam PF13426 PAS domain 142 246 2.4E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS05990 ffa6b0f16923ac739afd25b3ceb0ed97 683 Pfam PF00563 EAL domain 436 670 2.1E-70 T 28-03-2018 IPR001633 EAL domain MKLM6_RS05990 ffa6b0f16923ac739afd25b3ceb0ed97 683 Gene3D G3DSA:3.30.450.20 126 259 7.9E-32 T 28-03-2018 MKLM6_RS00355 38f76407b751eb2484519cb9de36c21a 1626 SUPERFAMILY SSF48239 1112 1387 1.69E-20 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid MKLM6_RS00355 38f76407b751eb2484519cb9de36c21a 1626 Gene3D G3DSA:2.60.40.10 800 962 1.5E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS00355 38f76407b751eb2484519cb9de36c21a 1626 Pfam PF01835 MG2 domain 325 422 7.3E-13 T 28-03-2018 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 MKLM6_RS00355 38f76407b751eb2484519cb9de36c21a 1626 Pfam PF10569 Alpha-macro-globulin thiol-ester bond-forming region 1116 1139 5.1E-5 T 28-03-2018 IPR019565 Alpha-2-macroglobulin, thiol-ester bond-forming MKLM6_RS00355 38f76407b751eb2484519cb9de36c21a 1626 SMART SM01359 705 851 5.0E-13 T 28-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 MKLM6_RS00355 38f76407b751eb2484519cb9de36c21a 1626 Gene3D G3DSA:1.50.10.20 1109 1389 5.5E-22 T 28-03-2018 MKLM6_RS00355 38f76407b751eb2484519cb9de36c21a 1626 Gene3D G3DSA:2.60.40.10 224 316 0.039 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS00355 38f76407b751eb2484519cb9de36c21a 1626 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 706 850 3.8E-7 T 28-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 MKLM6_RS00355 38f76407b751eb2484519cb9de36c21a 1626 SMART SM01360 912 1002 2.2E-18 T 28-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 MKLM6_RS00355 38f76407b751eb2484519cb9de36c21a 1626 Gene3D G3DSA:2.60.40.1310 546 697 0.12 T 28-03-2018 MKLM6_RS00355 38f76407b751eb2484519cb9de36c21a 1626 Gene3D G3DSA:2.60.40.10 324 417 0.1 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS00355 38f76407b751eb2484519cb9de36c21a 1626 Pfam PF00207 Alpha-2-macroglobulin family 912 998 2.8E-12 T 28-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 MKLM6_RS14550 b75e581df21012f33a886d547266d96b 72 Gene3D G3DSA:2.40.50.140 1 72 1.1E-35 T 28-03-2018 MKLM6_RS14550 b75e581df21012f33a886d547266d96b 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.345 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 MKLM6_RS14550 b75e581df21012f33a886d547266d96b 72 SMART SM00316 4 72 2.3E-6 T 28-03-2018 IPR022967 RNA-binding domain, S1 MKLM6_RS14550 b75e581df21012f33a886d547266d96b 72 SUPERFAMILY SSF50249 1 70 2.69E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS14550 b75e581df21012f33a886d547266d96b 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 9.7E-28 T 28-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 MKLM6_RS14550 b75e581df21012f33a886d547266d96b 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 1.7E-38 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 MKLM6_RS17665 ff742e5a65c0e14e3959ecd8dfd14be3 912 SUPERFAMILY SSF47384 672 749 2.35E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS17665 ff742e5a65c0e14e3959ecd8dfd14be3 912 SUPERFAMILY SSF52402 253 369 1.42E-12 T 28-03-2018 MKLM6_RS17665 ff742e5a65c0e14e3959ecd8dfd14be3 912 Pfam PF13492 GAF domain 577 660 3.4E-8 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS17665 ff742e5a65c0e14e3959ecd8dfd14be3 912 SUPERFAMILY SSF55874 738 902 1.31E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS17665 ff742e5a65c0e14e3959ecd8dfd14be3 912 Gene3D G3DSA:1.10.287.130 677 743 3.8E-15 T 28-03-2018 MKLM6_RS17665 ff742e5a65c0e14e3959ecd8dfd14be3 912 Gene3D G3DSA:3.30.450.40 515 676 1.8E-15 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS17665 ff742e5a65c0e14e3959ecd8dfd14be3 912 Pfam PF00512 His Kinase A (phospho-acceptor) domain 682 749 2.4E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS17665 ff742e5a65c0e14e3959ecd8dfd14be3 912 Pfam PF00582 Universal stress protein family 253 369 2.7E-8 T 28-03-2018 IPR006016 UspA GO:0006950 MKLM6_RS17665 ff742e5a65c0e14e3959ecd8dfd14be3 912 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 794 902 2.0E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS17665 ff742e5a65c0e14e3959ecd8dfd14be3 912 Gene3D G3DSA:3.40.50.620 229 370 5.5E-17 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS17665 ff742e5a65c0e14e3959ecd8dfd14be3 912 SMART SM00387 793 903 4.3E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS17665 ff742e5a65c0e14e3959ecd8dfd14be3 912 SUPERFAMILY SSF55781 524 677 2.4E-10 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS17665 ff742e5a65c0e14e3959ecd8dfd14be3 912 Gene3D G3DSA:3.40.50.300 23 155 1.7E-21 T 28-03-2018 MKLM6_RS17665 ff742e5a65c0e14e3959ecd8dfd14be3 912 PRINTS PR00344 Bacterial sensor protein C-terminal signature 863 881 4.6E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS17665 ff742e5a65c0e14e3959ecd8dfd14be3 912 PRINTS PR00344 Bacterial sensor protein C-terminal signature 830 844 4.6E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS17665 ff742e5a65c0e14e3959ecd8dfd14be3 912 PRINTS PR00344 Bacterial sensor protein C-terminal signature 848 858 4.6E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS17665 ff742e5a65c0e14e3959ecd8dfd14be3 912 PRINTS PR00344 Bacterial sensor protein C-terminal signature 887 900 4.6E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS17665 ff742e5a65c0e14e3959ecd8dfd14be3 912 Gene3D G3DSA:3.30.565.10 744 903 3.6E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS17665 ff742e5a65c0e14e3959ecd8dfd14be3 912 SMART SM00065 525 670 0.0048 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS17665 ff742e5a65c0e14e3959ecd8dfd14be3 912 SMART SM00388 681 749 6.7E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS17665 ff742e5a65c0e14e3959ecd8dfd14be3 912 Gene3D G3DSA:1.20.120.620 416 514 2.8E-26 T 28-03-2018 MKLM6_RS17665 ff742e5a65c0e14e3959ecd8dfd14be3 912 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 23 232 9.7E-97 T 28-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 MKLM6_RS17665 ff742e5a65c0e14e3959ecd8dfd14be3 912 Pfam PF13493 Domain of unknown function (DUF4118) 417 523 4.3E-29 T 28-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain MKLM6_RS02745 1e7eda534dec7e19b26c1594d9947229 698 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 21 695 3.5E-270 T 28-03-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 MKLM6_RS02745 1e7eda534dec7e19b26c1594d9947229 698 PIRSF PIRSF005419 4 698 2.6E-248 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MKLM6_RS02745 1e7eda534dec7e19b26c1594d9947229 698 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 143 166 - T 28-03-2018 IPR025505 FHIPEP conserved site MKLM6_RS02745 1e7eda534dec7e19b26c1594d9947229 698 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 157 175 3.0E-55 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MKLM6_RS02745 1e7eda534dec7e19b26c1594d9947229 698 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 187 204 3.0E-55 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MKLM6_RS02745 1e7eda534dec7e19b26c1594d9947229 698 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 34 47 3.0E-55 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MKLM6_RS02745 1e7eda534dec7e19b26c1594d9947229 698 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 238 252 3.0E-55 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MKLM6_RS02745 1e7eda534dec7e19b26c1594d9947229 698 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 71 90 3.0E-55 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MKLM6_RS02745 1e7eda534dec7e19b26c1594d9947229 698 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 138 154 3.0E-55 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MKLM6_RS02745 1e7eda534dec7e19b26c1594d9947229 698 Pfam PF00771 FHIPEP family 28 687 1.9E-272 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MKLM6_RS16255 69137cabb1f4c5e2c7a9d15f64a1568a 169 Pfam PF08463 EcoEI R protein C-terminal 10 125 4.1E-13 T 28-03-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 MKLM6_RS17750 9e6e57b8edd91d547cd875a0fea52614 77 SUPERFAMILY SSF89447 4 54 3.45E-6 T 28-03-2018 MKLM6_RS17750 9e6e57b8edd91d547cd875a0fea52614 77 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 56 1.7E-8 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 SMART SM00267 783 962 1.4E-57 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 Gene3D G3DSA:3.20.20.450 970 1222 1.6E-94 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 SUPERFAMILY SSF55785 678 780 1.5E-27 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 SUPERFAMILY SSF55073 799 964 3.77E-47 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 Pfam PF05231 MASE1 19 214 9.0E-18 T 28-03-2018 IPR007895 MASE1 MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 790 960 1.4E-40 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 Gene3D G3DSA:3.30.70.270 810 969 3.7E-57 T 28-03-2018 MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 Pfam PF00563 EAL domain 978 1214 6.8E-72 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 SMART SM00091 549 620 3.4E-8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 SMART SM00091 669 735 4.7E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 Pfam PF03924 CHASE domain 268 460 5.2E-37 T 28-03-2018 IPR006189 CHASE domain MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 Pfam PF00990 Diguanylate cyclase, GGDEF domain 794 957 1.3E-46 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 SUPERFAMILY SSF141868 977 1228 1.7E-84 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 553 669 1.3E-20 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 677 789 3.5E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 Gene3D G3DSA:3.30.450.20 531 675 6.4E-27 T 28-03-2018 MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 SUPERFAMILY SSF55785 560 670 3.38E-23 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 SMART SM00052 972 1219 8.5E-108 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 Pfam PF13426 PAS domain 680 781 2.5E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 Pfam PF13426 PAS domain 560 661 5.1E-13 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 SMART SM01079 264 462 5.3E-42 T 28-03-2018 IPR006189 CHASE domain MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 Gene3D G3DSA:3.30.450.20 676 809 2.9E-26 T 28-03-2018 MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 SMART SM00086 622 662 0.0021 T 28-03-2018 IPR001610 PAC motif MKLM6_RS14455 a49fb5041d1fdeec791f44e7bcb84ac6 1246 SMART SM00086 741 783 3.0E-4 T 28-03-2018 IPR001610 PAC motif MKLM6_RS12095 6c0974093afdbeaeb56d663501e97866 479 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 344 353 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MKLM6_RS12095 6c0974093afdbeaeb56d663501e97866 479 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 11 453 9.7E-162 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12095 6c0974093afdbeaeb56d663501e97866 479 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 479 35.877 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12095 6c0974093afdbeaeb56d663501e97866 479 SUPERFAMILY SSF52540 85 359 1.26E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS12095 6c0974093afdbeaeb56d663501e97866 479 SUPERFAMILY SSF47917 362 458 1.57E-21 T 28-03-2018 MKLM6_RS12095 6c0974093afdbeaeb56d663501e97866 479 Gene3D G3DSA:3.40.50.300 68 353 4.0E-93 T 28-03-2018 MKLM6_RS12095 6c0974093afdbeaeb56d663501e97866 479 Gene3D G3DSA:2.40.30.20 15 67 2.4E-14 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12095 6c0974093afdbeaeb56d663501e97866 479 SUPERFAMILY SSF50615 7 81 1.15E-14 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MKLM6_RS12095 6c0974093afdbeaeb56d663501e97866 479 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 360 453 6.0E-21 T 28-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12095 6c0974093afdbeaeb56d663501e97866 479 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 138 353 6.0E-61 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MKLM6_RS12095 6c0974093afdbeaeb56d663501e97866 479 Gene3D G3DSA:1.20.150.20 362 472 1.6E-22 T 28-03-2018 MKLM6_RS19235 b57c21621fc6198b680bd8d0b57e2b4d 408 Pfam PF00872 Transposase, Mutator family 20 384 5.7E-120 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS19235 b57c21621fc6198b680bd8d0b57e2b4d 408 ProSitePatterns PS01007 Transposases, Mutator family, signature. 239 263 - T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS21445 b57c21621fc6198b680bd8d0b57e2b4d 408 Pfam PF00872 Transposase, Mutator family 20 384 5.7E-120 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS21445 b57c21621fc6198b680bd8d0b57e2b4d 408 ProSitePatterns PS01007 Transposases, Mutator family, signature. 239 263 - T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS00270 b57c21621fc6198b680bd8d0b57e2b4d 408 Pfam PF00872 Transposase, Mutator family 20 384 5.7E-120 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS00270 b57c21621fc6198b680bd8d0b57e2b4d 408 ProSitePatterns PS01007 Transposases, Mutator family, signature. 239 263 - T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS05425 b57c21621fc6198b680bd8d0b57e2b4d 408 Pfam PF00872 Transposase, Mutator family 20 384 5.7E-120 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS05425 b57c21621fc6198b680bd8d0b57e2b4d 408 ProSitePatterns PS01007 Transposases, Mutator family, signature. 239 263 - T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS14460 b57c21621fc6198b680bd8d0b57e2b4d 408 Pfam PF00872 Transposase, Mutator family 20 384 5.7E-120 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS14460 b57c21621fc6198b680bd8d0b57e2b4d 408 ProSitePatterns PS01007 Transposases, Mutator family, signature. 239 263 - T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS18245 e314e96f1a1360afed9ec7d862afef07 314 Gene3D G3DSA:2.60.260.20 130 210 2.1E-16 T 28-03-2018 MKLM6_RS18245 e314e96f1a1360afed9ec7d862afef07 314 SUPERFAMILY SSF49493 216 297 1.31E-16 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MKLM6_RS18245 e314e96f1a1360afed9ec7d862afef07 314 PRINTS PR00625 DnaJ domain signature 61 80 1.1E-23 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS18245 e314e96f1a1360afed9ec7d862afef07 314 PRINTS PR00625 DnaJ domain signature 25 40 1.1E-23 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS18245 e314e96f1a1360afed9ec7d862afef07 314 PRINTS PR00625 DnaJ domain signature 41 61 1.1E-23 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS18245 e314e96f1a1360afed9ec7d862afef07 314 PRINTS PR00625 DnaJ domain signature 7 25 1.1E-23 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS18245 e314e96f1a1360afed9ec7d862afef07 314 Pfam PF00226 DnaJ domain 5 66 1.6E-24 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS18245 e314e96f1a1360afed9ec7d862afef07 314 SUPERFAMILY SSF46565 2 111 1.44E-31 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS18245 e314e96f1a1360afed9ec7d862afef07 314 Gene3D G3DSA:1.10.287.110 1 116 7.6E-33 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS18245 e314e96f1a1360afed9ec7d862afef07 314 Pfam PF01556 DnaJ C terminal domain 135 286 1.1E-29 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal MKLM6_RS18245 e314e96f1a1360afed9ec7d862afef07 314 Gene3D G3DSA:2.60.260.20 215 291 8.9E-17 T 28-03-2018 MKLM6_RS18245 e314e96f1a1360afed9ec7d862afef07 314 SMART SM00271 4 61 1.5E-27 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS18245 e314e96f1a1360afed9ec7d862afef07 314 SUPERFAMILY SSF49493 125 221 1.2E-16 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MKLM6_RS18245 e314e96f1a1360afed9ec7d862afef07 314 Gene3D G3DSA:1.20.5.460 292 311 1.1E-7 T 28-03-2018 MKLM6_RS00070 a94eec5a064dee24ed8d6a78e221c957 602 SMART SM00382 185 324 1.6E-25 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS00070 a94eec5a064dee24ed8d6a78e221c957 602 SUPERFAMILY SSF52540 145 391 2.36E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS00070 a94eec5a064dee24ed8d6a78e221c957 602 Pfam PF01434 Peptidase family M41 382 588 8.8E-72 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 MKLM6_RS00070 a94eec5a064dee24ed8d6a78e221c957 602 SUPERFAMILY SSF140990 404 597 1.44E-66 T 28-03-2018 MKLM6_RS00070 a94eec5a064dee24ed8d6a78e221c957 602 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 2 598 35.698 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 MKLM6_RS00070 a94eec5a064dee24ed8d6a78e221c957 602 Pfam PF06480 FtsH Extracellular 4 93 6.9E-8 T 28-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 MKLM6_RS00070 a94eec5a064dee24ed8d6a78e221c957 602 Gene3D G3DSA:3.40.50.300 128 332 1.8E-61 T 28-03-2018 MKLM6_RS00070 a94eec5a064dee24ed8d6a78e221c957 602 ProSitePatterns PS00674 AAA-protein family signature. 292 310 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 MKLM6_RS00070 a94eec5a064dee24ed8d6a78e221c957 602 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 189 321 5.7E-45 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MKLM6_RS00070 a94eec5a064dee24ed8d6a78e221c957 602 Gene3D G3DSA:1.10.8.60 333 408 9.2E-23 T 28-03-2018 MKLM6_RS00070 a94eec5a064dee24ed8d6a78e221c957 602 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 102 590 1.7E-219 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 MKLM6_RS12550 9f29ebb6617a4d4f7138ed5512fdd72c 215 Pfam PF00753 Metallo-beta-lactamase superfamily 9 192 2.7E-30 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS12550 9f29ebb6617a4d4f7138ed5512fdd72c 215 Gene3D G3DSA:3.60.15.10 1 213 9.2E-43 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS12550 9f29ebb6617a4d4f7138ed5512fdd72c 215 SUPERFAMILY SSF56281 1 209 2.23E-56 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS12550 9f29ebb6617a4d4f7138ed5512fdd72c 215 SMART SM00849 12 192 2.8E-40 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS00620 3fac6021826898b340489644d83399d2 94 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 26 82 7.4E-29 T 28-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MKLM6_RS00620 3fac6021826898b340489644d83399d2 94 ProSitePatterns PS00605 ATP synthase c subunit signature. 45 66 - T 28-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00620 3fac6021826898b340489644d83399d2 94 SUPERFAMILY SSF81333 9 84 2.62E-18 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 MKLM6_RS00620 3fac6021826898b340489644d83399d2 94 PRINTS PR00124 ATP synthase C subunit signature 55 80 9.8E-7 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00620 3fac6021826898b340489644d83399d2 94 PRINTS PR00124 ATP synthase C subunit signature 17 36 9.8E-7 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00620 3fac6021826898b340489644d83399d2 94 PRINTS PR00124 ATP synthase C subunit signature 38 53 9.8E-7 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00620 3fac6021826898b340489644d83399d2 94 Pfam PF00137 ATP synthase subunit C 16 79 6.8E-9 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 MKLM6_RS00620 3fac6021826898b340489644d83399d2 94 Gene3D G3DSA:1.20.20.10 10 82 4.2E-14 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 MKLM6_RS00620 3fac6021826898b340489644d83399d2 94 Hamap MF_01396 ATP synthase subunit c [atpH]. 15 80 13.9 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS22415 5e25adf5cb2fc8c25782371ffa7b1b9c 711 Gene3D G3DSA:2.60.40.10 432 528 5.4E-12 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS22415 5e25adf5cb2fc8c25782371ffa7b1b9c 711 SUPERFAMILY SSF49313 439 529 1.37E-7 T 28-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 MKLM6_RS09680 14fb0fabe368057efb4707d895557540 351 SUPERFAMILY SSF103088 242 348 8.5E-30 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS09680 14fb0fabe368057efb4707d895557540 351 SUPERFAMILY SSF103647 204 239 1.7E-5 T 28-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 MKLM6_RS09680 14fb0fabe368057efb4707d895557540 351 Gene3D G3DSA:2.40.160.20 15 208 8.1E-18 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MKLM6_RS09680 14fb0fabe368057efb4707d895557540 351 Pfam PF13505 Outer membrane protein beta-barrel domain 13 177 1.0E-10 T 28-03-2018 IPR027385 Outer membrane protein beta-barrel MKLM6_RS09680 14fb0fabe368057efb4707d895557540 351 SUPERFAMILY SSF56925 28 176 1.86E-16 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MKLM6_RS09680 14fb0fabe368057efb4707d895557540 351 PRINTS PR01021 OMPA domain signature 279 294 1.3E-13 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MKLM6_RS09680 14fb0fabe368057efb4707d895557540 351 PRINTS PR01021 OMPA domain signature 294 310 1.3E-13 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MKLM6_RS09680 14fb0fabe368057efb4707d895557540 351 PRINTS PR01021 OMPA domain signature 248 270 1.3E-13 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MKLM6_RS09680 14fb0fabe368057efb4707d895557540 351 Pfam PF00691 OmpA family 248 342 6.1E-22 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS09680 14fb0fabe368057efb4707d895557540 351 Gene3D G3DSA:3.30.1330.60 220 351 8.3E-33 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS16430 52d6bc0a74da2bfbfa3515aaf0d4f7b3 302 SUPERFAMILY SSF51735 115 228 3.72E-13 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS16430 52d6bc0a74da2bfbfa3515aaf0d4f7b3 302 Pfam PF09176 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal 18 98 8.8E-36 T 28-03-2018 IPR015259 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal MKLM6_RS16430 52d6bc0a74da2bfbfa3515aaf0d4f7b3 302 Gene3D G3DSA:3.40.50.720 115 271 2.1E-11 T 28-03-2018 MKLM6_RS16430 52d6bc0a74da2bfbfa3515aaf0d4f7b3 302 SUPERFAMILY SSF53223 5 98 3.74E-37 T 28-03-2018 MKLM6_RS16430 52d6bc0a74da2bfbfa3515aaf0d4f7b3 302 Gene3D G3DSA:3.40.50.10280 5 114 6.3E-51 T 28-03-2018 IPR015259 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal MKLM6_RS10715 30f11bb5bfa984bf5196148f6a53570a 581 Pfam PF01368 DHH family 77 181 7.2E-8 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MKLM6_RS10715 30f11bb5bfa984bf5196148f6a53570a 581 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 26 574 4.5E-140 T 28-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 MKLM6_RS10715 30f11bb5bfa984bf5196148f6a53570a 581 Gene3D G3DSA:3.90.1640.10 57 247 1.0E-18 T 28-03-2018 MKLM6_RS10715 30f11bb5bfa984bf5196148f6a53570a 581 SUPERFAMILY SSF64182 51 470 5.36E-109 T 28-03-2018 MKLM6_RS10715 30f11bb5bfa984bf5196148f6a53570a 581 Pfam PF02272 DHHA1 domain 325 455 1.4E-26 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 MKLM6_RS06030 56241d61737beb84ab97bd48a7763177 175 Gene3D G3DSA:3.30.530.20 11 175 2.9E-25 T 28-03-2018 IPR023393 START-like domain MKLM6_RS06030 56241d61737beb84ab97bd48a7763177 175 SUPERFAMILY SSF55961 25 174 5.9E-24 T 28-03-2018 MKLM6_RS06030 56241d61737beb84ab97bd48a7763177 175 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 26 174 7.9E-23 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase MKLM6_RS18705 51dc9038f19cbcb2d3a3db4d4d2457e8 354 SUPERFAMILY SSF52317 314 334 1.0E-71 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS18705 51dc9038f19cbcb2d3a3db4d4d2457e8 354 SUPERFAMILY SSF52317 18 285 1.0E-71 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS18705 51dc9038f19cbcb2d3a3db4d4d2457e8 354 PIRSF PIRSF000450 275 341 0.0091 T 28-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 MKLM6_RS18705 51dc9038f19cbcb2d3a3db4d4d2457e8 354 PIRSF PIRSF000450 1 294 1.8E-59 T 28-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 MKLM6_RS18705 51dc9038f19cbcb2d3a3db4d4d2457e8 354 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 35 255 3.0E-98 T 28-03-2018 MKLM6_RS18705 51dc9038f19cbcb2d3a3db4d4d2457e8 354 Gene3D G3DSA:3.40.50.880 34 338 1.1E-39 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS18705 51dc9038f19cbcb2d3a3db4d4d2457e8 354 Pfam PF04204 Homoserine O-succinyltransferase 2 334 1.5E-89 T 28-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 MKLM6_RS20440 fab3438a9d73a28640f8bc254c627682 550 SUPERFAMILY SSF55124 1 125 1.44E-28 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MKLM6_RS20440 fab3438a9d73a28640f8bc254c627682 550 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 413 546 4.7E-11 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MKLM6_RS20440 fab3438a9d73a28640f8bc254c627682 550 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 119 272 2.6E-45 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MKLM6_RS20440 fab3438a9d73a28640f8bc254c627682 550 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 53 109 8.8E-16 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MKLM6_RS20440 fab3438a9d73a28640f8bc254c627682 550 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 346 397 3.7E-16 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MKLM6_RS20440 fab3438a9d73a28640f8bc254c627682 550 Gene3D G3DSA:3.30.413.10 404 549 4.5E-31 T 28-03-2018 MKLM6_RS20440 fab3438a9d73a28640f8bc254c627682 550 Gene3D G3DSA:3.30.413.10 120 238 3.4E-29 T 28-03-2018 MKLM6_RS20440 fab3438a9d73a28640f8bc254c627682 550 SUPERFAMILY SSF55124 252 276 2.29E-25 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MKLM6_RS20440 fab3438a9d73a28640f8bc254c627682 550 SUPERFAMILY SSF55124 314 420 2.29E-25 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MKLM6_RS20440 fab3438a9d73a28640f8bc254c627682 550 SUPERFAMILY SSF56014 120 277 9.03E-49 T 28-03-2018 MKLM6_RS20440 fab3438a9d73a28640f8bc254c627682 550 SUPERFAMILY SSF56014 406 547 3.14E-38 T 28-03-2018 MKLM6_RS20440 fab3438a9d73a28640f8bc254c627682 550 Gene3D G3DSA:3.90.480.10 239 403 4.8E-19 T 28-03-2018 MKLM6_RS21155 e7e3037541645665b36508498bddd4f5 627 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 8 627 33.607 T 28-03-2018 IPR023051 Potassium uptake protein, low affinity, Kup MKLM6_RS21155 e7e3037541645665b36508498bddd4f5 627 Pfam PF02705 K+ potassium transporter 16 549 2.1E-213 T 28-03-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 MKLM6_RS13925 36cd58b64a0a219c119bfa5289390890 295 Pfam PF00990 Diguanylate cyclase, GGDEF domain 134 290 8.3E-48 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS13925 36cd58b64a0a219c119bfa5289390890 295 SUPERFAMILY SSF55073 139 292 2.28E-49 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS13925 36cd58b64a0a219c119bfa5289390890 295 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 132 292 1.7E-53 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS13925 36cd58b64a0a219c119bfa5289390890 295 SMART SM00267 123 294 5.8E-64 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS13925 36cd58b64a0a219c119bfa5289390890 295 Gene3D G3DSA:3.30.70.270 127 294 2.4E-57 T 28-03-2018 MKLM6_RS02310 d1d313baa10986cd26ec265b9f30efa9 511 Pfam PF00361 Proton-conducting membrane transporter 144 426 1.5E-37 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS02310 d1d313baa10986cd26ec265b9f30efa9 511 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 17 493 9.0E-83 T 28-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS02310 d1d313baa10986cd26ec265b9f30efa9 511 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 332 351 7.5E-7 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS02310 d1d313baa10986cd26ec265b9f30efa9 511 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 244 268 7.5E-7 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS02310 d1d313baa10986cd26ec265b9f30efa9 511 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 384 410 7.5E-7 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS16090 5fbccff75ab0a3d83b0e00f11da5090e 171 Gene3D G3DSA:3.40.220.10 1 170 3.2E-73 T 28-03-2018 MKLM6_RS16090 5fbccff75ab0a3d83b0e00f11da5090e 171 Pfam PF01661 Macro domain 21 133 1.5E-44 T 28-03-2018 IPR002589 Macro domain MKLM6_RS16090 5fbccff75ab0a3d83b0e00f11da5090e 171 SUPERFAMILY SSF52949 3 169 5.38E-64 T 28-03-2018 MKLM6_RS16090 5fbccff75ab0a3d83b0e00f11da5090e 171 SMART SM00506 4 133 3.5E-47 T 28-03-2018 IPR002589 Macro domain MKLM6_RS00880 686868b67e59e9a914cdb3d3fd1beba8 209 Gene3D G3DSA:1.10.10.10 1 69 1.9E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS00880 686868b67e59e9a914cdb3d3fd1beba8 209 Gene3D G3DSA:2.10.109.10 88 205 2.2E-21 T 28-03-2018 MKLM6_RS00880 686868b67e59e9a914cdb3d3fd1beba8 209 SUPERFAMILY SSF51306 83 203 3.14E-27 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MKLM6_RS00880 686868b67e59e9a914cdb3d3fd1beba8 209 SUPERFAMILY SSF46785 1 69 1.17E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS00880 686868b67e59e9a914cdb3d3fd1beba8 209 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 118 128 3.5E-6 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MKLM6_RS00880 686868b67e59e9a914cdb3d3fd1beba8 209 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 129 140 3.5E-6 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MKLM6_RS00880 686868b67e59e9a914cdb3d3fd1beba8 209 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 158 170 3.5E-6 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MKLM6_RS00880 686868b67e59e9a914cdb3d3fd1beba8 209 Pfam PF00717 Peptidase S24-like 121 186 7.1E-12 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MKLM6_RS00880 686868b67e59e9a914cdb3d3fd1beba8 209 TIGRFAM TIGR00498 lexA: repressor LexA 2 204 1.6E-46 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 MKLM6_RS00880 686868b67e59e9a914cdb3d3fd1beba8 209 Pfam PF01726 LexA DNA binding domain 2 64 2.3E-10 T 28-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 MKLM6_RS00880 686868b67e59e9a914cdb3d3fd1beba8 209 Hamap MF_00015 LexA repressor [lexA]. 2 205 27.831 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 MKLM6_RS04280 4d5221d9501bb33c11a2402ba178dd3a 108 Pfam PF11985 Protein of unknown function (DUF3486) 3 62 8.8E-8 T 28-03-2018 IPR021874 Bacteriophage Mu, Gp27 MKLM6_RS13590 eec19976a9ab0165ed06a40a7983dce6 273 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 11 240 1.0E-40 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA MKLM6_RS13590 eec19976a9ab0165ed06a40a7983dce6 273 Pfam PF13242 HAD-hyrolase-like 191 263 1.2E-20 T 28-03-2018 MKLM6_RS13590 eec19976a9ab0165ed06a40a7983dce6 273 Pfam PF13344 Haloacid dehalogenase-like hydrolase 11 112 1.1E-23 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA MKLM6_RS13590 eec19976a9ab0165ed06a40a7983dce6 273 PIRSF PIRSF000915 2 269 4.5E-56 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA MKLM6_RS13590 eec19976a9ab0165ed06a40a7983dce6 273 Gene3D G3DSA:3.40.50.1000 7 87 2.1E-7 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS13590 eec19976a9ab0165ed06a40a7983dce6 273 SUPERFAMILY SSF56784 7 263 7.46E-62 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS13590 eec19976a9ab0165ed06a40a7983dce6 273 Gene3D G3DSA:3.40.50.1000 88 191 3.6E-30 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS10215 45a956b74d7124834705f77132b0bed9 236 PIRSF PIRSF019345 1 205 2.7E-65 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 MKLM6_RS10215 45a956b74d7124834705f77132b0bed9 236 SUPERFAMILY SSF46785 81 157 1.2E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS10215 45a956b74d7124834705f77132b0bed9 236 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 3 172 6.0E-37 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 MKLM6_RS10215 45a956b74d7124834705f77132b0bed9 236 Pfam PF04079 Segregation and condensation complex subunit ScpB 5 166 5.2E-53 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 MKLM6_RS10215 45a956b74d7124834705f77132b0bed9 236 SUPERFAMILY SSF46785 2 79 1.97E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS10215 45a956b74d7124834705f77132b0bed9 236 Gene3D G3DSA:1.10.10.10 1 81 3.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS10215 45a956b74d7124834705f77132b0bed9 236 Gene3D G3DSA:1.10.10.10 82 173 3.8E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS16565 002c09aac90209d9c910367ac53c537e 557 Gene3D G3DSA:3.60.40.10 133 377 2.7E-16 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS16565 002c09aac90209d9c910367ac53c537e 557 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 187 373 9.6E-28 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS16565 002c09aac90209d9c910367ac53c537e 557 SUPERFAMILY SSF55874 414 545 5.42E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS16565 002c09aac90209d9c910367ac53c537e 557 Gene3D G3DSA:3.30.565.10 393 546 4.8E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS16565 002c09aac90209d9c910367ac53c537e 557 Pfam PF13581 Histidine kinase-like ATPase domain 424 552 1.8E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS16565 002c09aac90209d9c910367ac53c537e 557 SUPERFAMILY SSF52172 18 135 2.85E-11 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS16565 002c09aac90209d9c910367ac53c537e 557 Gene3D G3DSA:3.40.50.2300 13 132 9.3E-9 T 28-03-2018 MKLM6_RS16565 002c09aac90209d9c910367ac53c537e 557 SMART SM00331 161 374 1.5E-8 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS07285 5a1c42e06d62dc582d115e756204ff16 163 Pfam PF13511 Domain of unknown function (DUF4124) 9 60 8.9E-12 T 28-03-2018 IPR025392 Domain of unknown function DUF4124 MKLM6_RS06710 b198b6a8e9a874c323b9a9e9d04e5057 105 Pfam PF00699 Urease beta subunit 3 99 7.2E-47 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MKLM6_RS06710 b198b6a8e9a874c323b9a9e9d04e5057 105 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 102 1.8E-46 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MKLM6_RS06710 b198b6a8e9a874c323b9a9e9d04e5057 105 SUPERFAMILY SSF51278 1 103 2.35E-49 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MKLM6_RS06710 b198b6a8e9a874c323b9a9e9d04e5057 105 Gene3D G3DSA:2.10.150.10 1 101 9.2E-48 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MKLM6_RS06710 b198b6a8e9a874c323b9a9e9d04e5057 105 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 33.049 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MKLM6_RS12910 fa675f2b22fc4589f72ca8dd839ef179 451 SUPERFAMILY SSF51230 64 100 9.6E-6 T 28-03-2018 IPR011053 Single hybrid motif MKLM6_RS12910 fa675f2b22fc4589f72ca8dd839ef179 451 SUPERFAMILY SSF51230 275 315 9.11E-5 T 28-03-2018 IPR011053 Single hybrid motif MKLM6_RS12910 fa675f2b22fc4589f72ca8dd839ef179 451 Gene3D G3DSA:1.20.1600.10 116 369 5.1E-10 T 28-03-2018 MKLM6_RS12910 fa675f2b22fc4589f72ca8dd839ef179 451 Pfam PF13533 Biotin-lipoyl like 68 105 5.5E-9 T 28-03-2018 MKLM6_RS12910 fa675f2b22fc4589f72ca8dd839ef179 451 Pfam PF13437 HlyD family secretion protein 279 345 9.3E-9 T 28-03-2018 MKLM6_RS12910 fa675f2b22fc4589f72ca8dd839ef179 451 Gene3D G3DSA:3.90.1170.30 18 115 3.5E-9 T 28-03-2018 MKLM6_RS12910 fa675f2b22fc4589f72ca8dd839ef179 451 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 325 349 3.1E-9 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MKLM6_RS12910 fa675f2b22fc4589f72ca8dd839ef179 451 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 79 99 3.1E-9 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MKLM6_RS12910 fa675f2b22fc4589f72ca8dd839ef179 451 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 292 313 3.1E-9 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MKLM6_RS17745 82e090ed9d980ebc534b3610eea05062 127 Pfam PF01850 PIN domain 1 104 1.1E-9 T 28-03-2018 IPR002716 PIN domain MKLM6_RS17745 82e090ed9d980ebc534b3610eea05062 127 Gene3D G3DSA:3.40.50.1010 1 122 2.5E-22 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS17745 82e090ed9d980ebc534b3610eea05062 127 SUPERFAMILY SSF88723 2 121 8.97E-22 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS22635 b0c32e6bbc41fafd13dce9bd2e949f06 208 Pfam PF00589 Phage integrase family 41 192 2.3E-19 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS22635 b0c32e6bbc41fafd13dce9bd2e949f06 208 SUPERFAMILY SSF56349 22 205 5.59E-35 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS22635 b0c32e6bbc41fafd13dce9bd2e949f06 208 Gene3D G3DSA:1.10.443.10 22 198 5.5E-24 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS16590 d6537923cc0257e693a493d56d1daf2c 211 Pfam PF09335 SNARE associated Golgi protein 49 171 2.5E-24 T 28-03-2018 IPR032816 SNARE associated Golgi protein MKLM6_RS09415 19ac5816a8aa5e63d17c7482d08d915b 451 Gene3D G3DSA:3.40.1480.10 270 451 3.1E-57 T 28-03-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 MKLM6_RS09415 19ac5816a8aa5e63d17c7482d08d915b 451 Pfam PF05161 MOFRL family 334 441 3.6E-36 T 28-03-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 MKLM6_RS09415 19ac5816a8aa5e63d17c7482d08d915b 451 Pfam PF13660 Domain of unknown function (DUF4147) 13 252 5.5E-78 T 28-03-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 MKLM6_RS09415 19ac5816a8aa5e63d17c7482d08d915b 451 SUPERFAMILY SSF82544 10 447 3.27E-125 T 28-03-2018 MKLM6_RS09415 19ac5816a8aa5e63d17c7482d08d915b 451 Gene3D G3DSA:3.40.50.10180 25 269 3.4E-84 T 28-03-2018 MKLM6_RS05970 5736ba4de1265965e6023d4d4b0e111b 288 Gene3D G3DSA:3.90.550.10 2 234 6.4E-24 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS05970 5736ba4de1265965e6023d4d4b0e111b 288 SUPERFAMILY SSF53448 1 250 1.03E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS05970 5736ba4de1265965e6023d4d4b0e111b 288 Pfam PF00535 Glycosyl transferase family 2 14 133 8.4E-16 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MKLM6_RS17120 c8f0ea536d025b96e5f5befed8675ea6 407 PRINTS PR00812 Bacterial general secretion pathway protein F signature 372 386 9.5E-10 T 28-03-2018 IPR003004 GspF/PilC family MKLM6_RS17120 c8f0ea536d025b96e5f5befed8675ea6 407 PRINTS PR00812 Bacterial general secretion pathway protein F signature 388 407 9.5E-10 T 28-03-2018 IPR003004 GspF/PilC family MKLM6_RS17120 c8f0ea536d025b96e5f5befed8675ea6 407 PRINTS PR00812 Bacterial general secretion pathway protein F signature 71 83 9.5E-10 T 28-03-2018 IPR003004 GspF/PilC family MKLM6_RS17120 c8f0ea536d025b96e5f5befed8675ea6 407 PRINTS PR00812 Bacterial general secretion pathway protein F signature 170 198 9.5E-10 T 28-03-2018 IPR003004 GspF/PilC family MKLM6_RS17120 c8f0ea536d025b96e5f5befed8675ea6 407 Gene3D G3DSA:3.30.70.1120 108 176 0.031 T 28-03-2018 MKLM6_RS17120 c8f0ea536d025b96e5f5befed8675ea6 407 Pfam PF00482 Type II secretion system (T2SS), protein F 75 198 5.5E-30 T 28-03-2018 IPR018076 Type II secretion system F domain MKLM6_RS17120 c8f0ea536d025b96e5f5befed8675ea6 407 Pfam PF00482 Type II secretion system (T2SS), protein F 282 396 5.0E-23 T 28-03-2018 IPR018076 Type II secretion system F domain MKLM6_RS16615 d98b8cebd7cd0d8e5c1a48f8ec53c150 178 PIRSF PIRSF015617 1 178 2.7E-66 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 MKLM6_RS16615 d98b8cebd7cd0d8e5c1a48f8ec53c150 178 SUPERFAMILY SSF52540 6 178 2.69E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS16615 d98b8cebd7cd0d8e5c1a48f8ec53c150 178 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 6 178 2.7E-59 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 MKLM6_RS16615 d98b8cebd7cd0d8e5c1a48f8ec53c150 178 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 8 178 3.1E-62 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 MKLM6_RS16615 d98b8cebd7cd0d8e5c1a48f8ec53c150 178 Gene3D G3DSA:3.40.50.300 1 178 5.6E-70 T 28-03-2018 MKLM6_RS14380 468324729f01770dedcea34ce9eee9c3 473 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 359 368 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site MKLM6_RS14380 468324729f01770dedcea34ce9eee9c3 473 Gene3D G3DSA:3.40.50.300 153 318 5.2E-26 T 28-03-2018 MKLM6_RS14380 468324729f01770dedcea34ce9eee9c3 473 Pfam PF00072 Response regulator receiver domain 5 113 9.0E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14380 468324729f01770dedcea34ce9eee9c3 473 Pfam PF00158 Sigma-54 interaction domain 146 312 4.0E-65 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MKLM6_RS14380 468324729f01770dedcea34ce9eee9c3 473 Gene3D G3DSA:1.10.10.60 380 473 8.1E-10 T 28-03-2018 MKLM6_RS14380 468324729f01770dedcea34ce9eee9c3 473 Gene3D G3DSA:3.40.50.2300 2 152 4.4E-24 T 28-03-2018 MKLM6_RS14380 468324729f01770dedcea34ce9eee9c3 473 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 436 453 7.2E-6 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS14380 468324729f01770dedcea34ce9eee9c3 473 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 453 473 7.2E-6 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS14380 468324729f01770dedcea34ce9eee9c3 473 SUPERFAMILY SSF52172 4 190 1.57E-31 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS14380 468324729f01770dedcea34ce9eee9c3 473 SMART SM00448 3 116 4.4E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS14380 468324729f01770dedcea34ce9eee9c3 473 SMART SM00382 166 309 6.4E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS14380 468324729f01770dedcea34ce9eee9c3 473 Pfam PF02954 Bacterial regulatory protein, Fis family 430 470 2.7E-6 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS14380 468324729f01770dedcea34ce9eee9c3 473 SUPERFAMILY SSF46689 423 472 1.25E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS14380 468324729f01770dedcea34ce9eee9c3 473 SUPERFAMILY SSF52540 147 387 4.2E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS14380 468324729f01770dedcea34ce9eee9c3 473 Gene3D G3DSA:1.10.8.60 319 379 8.5E-19 T 28-03-2018 MKLM6_RS14685 a7b08d1811286400b31319d5f4ba4862 139 Gene3D G3DSA:3.30.70.100 20 134 2.4E-13 T 28-03-2018 MKLM6_RS14685 a7b08d1811286400b31319d5f4ba4862 139 SUPERFAMILY SSF54909 33 134 8.26E-14 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel MKLM6_RS14685 a7b08d1811286400b31319d5f4ba4862 139 SMART SM00886 33 135 5.9E-10 T 28-03-2018 IPR013097 Stress responsive alpha-beta barrel MKLM6_RS14685 a7b08d1811286400b31319d5f4ba4862 139 Pfam PF07876 Stress responsive A/B Barrel Domain 34 133 3.5E-7 T 28-03-2018 IPR013097 Stress responsive alpha-beta barrel MKLM6_RS12850 458b5ed5bb7d00aebcbab0395b917fd5 314 PIRSF PIRSF006278 9 314 1.5E-83 T 28-03-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase MKLM6_RS12850 458b5ed5bb7d00aebcbab0395b917fd5 314 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 25 305 1.5E-21 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MKLM6_RS12850 458b5ed5bb7d00aebcbab0395b917fd5 314 SUPERFAMILY SSF53686 24 310 1.2E-58 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MKLM6_RS12850 458b5ed5bb7d00aebcbab0395b917fd5 314 Gene3D G3DSA:3.40.50.1100 149 312 9.7E-18 T 28-03-2018 MKLM6_RS12850 458b5ed5bb7d00aebcbab0395b917fd5 314 Gene3D G3DSA:3.40.50.1100 57 148 2.4E-25 T 28-03-2018 MKLM6_RS15600 4736df01b9cb48b0eadd7ca5f09be5d8 137 SMART SM00671 21 57 1.8E-6 T 28-03-2018 IPR006597 Sel1-like repeat MKLM6_RS15600 4736df01b9cb48b0eadd7ca5f09be5d8 137 SMART SM00671 58 93 3.5E-11 T 28-03-2018 IPR006597 Sel1-like repeat MKLM6_RS15600 4736df01b9cb48b0eadd7ca5f09be5d8 137 Gene3D G3DSA:2.60.40.1180 3 94 2.3E-18 T 28-03-2018 MKLM6_RS15600 4736df01b9cb48b0eadd7ca5f09be5d8 137 Pfam PF08238 Sel1 repeat 21 56 1.3E-8 T 28-03-2018 IPR006597 Sel1-like repeat MKLM6_RS15600 4736df01b9cb48b0eadd7ca5f09be5d8 137 Pfam PF08238 Sel1 repeat 59 93 5.1E-10 T 28-03-2018 IPR006597 Sel1-like repeat MKLM6_RS15600 4736df01b9cb48b0eadd7ca5f09be5d8 137 SUPERFAMILY SSF81901 11 102 1.27E-22 T 28-03-2018 MKLM6_RS08385 7b4a8b69c43721d354b9520cee376774 462 Pfam PF00589 Phage integrase family 248 447 7.6E-38 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS08385 7b4a8b69c43721d354b9520cee376774 462 Gene3D G3DSA:1.10.443.10 246 451 2.4E-38 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS08385 7b4a8b69c43721d354b9520cee376774 462 Gene3D G3DSA:1.10.150.130 145 232 5.2E-10 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal MKLM6_RS08385 7b4a8b69c43721d354b9520cee376774 462 TIGRFAM TIGR02249 integrase_gron: integron integrase 150 461 3.1E-113 T 28-03-2018 IPR011946 Integrase, integron-type GO:0003677|GO:0006310|GO:0015074 MKLM6_RS08385 7b4a8b69c43721d354b9520cee376774 462 SUPERFAMILY SSF56349 147 452 1.0E-39 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS08385 7b4a8b69c43721d354b9520cee376774 462 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 149 230 4.0E-18 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MKLM6_RS17220 3bdc6131b2753b2e2aa98d7000907ea9 843 Pfam PF14403 Circularly permuted ATP-grasp type 2 87 463 4.5E-154 T 28-03-2018 IPR025841 Circularly permuted ATP-grasp type 2 MKLM6_RS17220 3bdc6131b2753b2e2aa98d7000907ea9 843 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 509 833 3.4E-69 T 28-03-2018 IPR007296 Domain of unknown function DUF403 MKLM6_RS17220 3bdc6131b2753b2e2aa98d7000907ea9 843 SUPERFAMILY SSF56059 332 461 4.94E-23 T 28-03-2018 MKLM6_RS17220 3bdc6131b2753b2e2aa98d7000907ea9 843 SUPERFAMILY SSF56059 31 225 4.94E-23 T 28-03-2018 MKLM6_RS19195 9cb36e25b676277f5badab2521878fdc 819 Pfam PF02412 Thrombospondin type 3 repeat 726 747 1.4E-4 T 28-03-2018 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 MKLM6_RS19195 9cb36e25b676277f5badab2521878fdc 819 ProSitePatterns PS00018 EF-hand calcium-binding domain. 789 801 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site MKLM6_RS19195 9cb36e25b676277f5badab2521878fdc 819 Gene3D G3DSA:1.10.780.10 182 478 3.1E-21 T 28-03-2018 MKLM6_RS19195 9cb36e25b676277f5badab2521878fdc 819 SUPERFAMILY SSF49785 21 183 6.46E-8 T 28-03-2018 IPR008979 Galactose-binding domain-like MKLM6_RS19195 9cb36e25b676277f5badab2521878fdc 819 Gene3D G3DSA:4.10.1080.10 544 802 2.7E-11 T 28-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 MKLM6_RS19195 9cb36e25b676277f5badab2521878fdc 819 SUPERFAMILY SSF63446 764 810 1.28E-5 T 28-03-2018 IPR016134 Dockerin domain GO:0000272 MKLM6_RS19195 9cb36e25b676277f5badab2521878fdc 819 SUPERFAMILY SSF103647 724 778 1.05E-8 T 28-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 MKLM6_RS19195 9cb36e25b676277f5badab2521878fdc 819 Pfam PF13435 Cytochrome c554 and c-prime 217 324 3.1E-4 T 28-03-2018 IPR023155 Cytochrome c-552/4 MKLM6_RS19195 9cb36e25b676277f5badab2521878fdc 819 Pfam PF04862 Protein of unknown function (DUF642) 24 170 7.9E-8 T 28-03-2018 IPR006946 Domain of unknown function DUF642 MKLM6_RS19195 9cb36e25b676277f5badab2521878fdc 819 SUPERFAMILY SSF48695 212 438 6.99E-16 T 28-03-2018 IPR011031 Multihaem cytochrome MKLM6_RS19195 9cb36e25b676277f5badab2521878fdc 819 Gene3D G3DSA:2.60.120.260 16 181 4.6E-17 T 28-03-2018 IPR008979 Galactose-binding domain-like MKLM6_RS03085 e831243085702508b6e76b02906730ea 790 Gene3D G3DSA:3.30.450.20 360 497 2.0E-16 T 28-03-2018 MKLM6_RS03085 e831243085702508b6e76b02906730ea 790 Pfam PF00990 Diguanylate cyclase, GGDEF domain 624 780 4.7E-37 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS03085 e831243085702508b6e76b02906730ea 790 SUPERFAMILY SSF55785 366 489 2.44E-14 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03085 e831243085702508b6e76b02906730ea 790 Pfam PF05231 MASE1 92 358 1.3E-24 T 28-03-2018 IPR007895 MASE1 MKLM6_RS03085 e831243085702508b6e76b02906730ea 790 SUPERFAMILY SSF55073 629 780 1.73E-35 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS03085 e831243085702508b6e76b02906730ea 790 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 620 780 4.0E-33 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS03085 e831243085702508b6e76b02906730ea 790 SMART SM00267 613 784 7.6E-45 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS03085 e831243085702508b6e76b02906730ea 790 SMART SM00086 453 491 3.0 T 28-03-2018 IPR001610 PAC motif MKLM6_RS03085 e831243085702508b6e76b02906730ea 790 SMART SM00086 571 613 0.0031 T 28-03-2018 IPR001610 PAC motif MKLM6_RS03085 e831243085702508b6e76b02906730ea 790 Gene3D G3DSA:3.30.70.270 617 783 2.5E-47 T 28-03-2018 MKLM6_RS03085 e831243085702508b6e76b02906730ea 790 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 504 620 7.2E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03085 e831243085702508b6e76b02906730ea 790 Pfam PF08447 PAS fold 410 473 1.3E-8 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS03085 e831243085702508b6e76b02906730ea 790 Pfam PF13426 PAS domain 510 612 1.1E-14 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03085 e831243085702508b6e76b02906730ea 790 SMART SM00091 499 565 6.7E-4 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03085 e831243085702508b6e76b02906730ea 790 SUPERFAMILY SSF55785 507 610 3.49E-26 T 28-03-2018 IPR000014 PAS domain MKLM6_RS03085 e831243085702508b6e76b02906730ea 790 Gene3D G3DSA:3.40.50.10600 498 616 8.8E-26 T 28-03-2018 MKLM6_RS20125 2d19330d696d585eebdd4da3707ea405 716 Gene3D G3DSA:2.170.130.10 33 171 1.9E-28 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS20125 2d19330d696d585eebdd4da3707ea405 716 Pfam PF07715 TonB-dependent Receptor Plug Domain 53 162 7.0E-22 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS20125 2d19330d696d585eebdd4da3707ea405 716 SUPERFAMILY SSF56935 44 716 1.47E-109 T 28-03-2018 MKLM6_RS20125 2d19330d696d585eebdd4da3707ea405 716 Pfam PF00593 TonB dependent receptor 260 714 4.6E-49 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS20125 2d19330d696d585eebdd4da3707ea405 716 Gene3D G3DSA:2.40.170.20 172 716 3.4E-71 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS18470 283c76b9d5baaf510b1b6e678e7e7f2c 1399 Pfam PF05000 RNA polymerase Rpb1, domain 4 669 759 9.1E-19 T 28-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18470 283c76b9d5baaf510b1b6e678e7e7f2c 1399 Gene3D G3DSA:2.40.50.100 1018 1122 9.4E-13 T 28-03-2018 MKLM6_RS18470 283c76b9d5baaf510b1b6e678e7e7f2c 1399 Gene3D G3DSA:2.40.50.100 903 1017 1.1E-30 T 28-03-2018 MKLM6_RS18470 283c76b9d5baaf510b1b6e678e7e7f2c 1399 Gene3D G3DSA:2.40.50.100 1149 1208 8.3E-14 T 28-03-2018 MKLM6_RS18470 283c76b9d5baaf510b1b6e678e7e7f2c 1399 SUPERFAMILY SSF64484 12 940 0.0 T 28-03-2018 MKLM6_RS18470 283c76b9d5baaf510b1b6e678e7e7f2c 1399 SUPERFAMILY SSF64484 1129 1361 0.0 T 28-03-2018 MKLM6_RS18470 283c76b9d5baaf510b1b6e678e7e7f2c 1399 Pfam PF04998 RNA polymerase Rpb1, domain 5 762 1310 6.8E-78 T 28-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18470 283c76b9d5baaf510b1b6e678e7e7f2c 1399 Pfam PF04997 RNA polymerase Rpb1, domain 1 12 338 4.8E-86 T 28-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18470 283c76b9d5baaf510b1b6e678e7e7f2c 1399 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 1 1372 18.773 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18470 283c76b9d5baaf510b1b6e678e7e7f2c 1399 Pfam PF00623 RNA polymerase Rpb1, domain 2 388 481 3.1E-27 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18470 283c76b9d5baaf510b1b6e678e7e7f2c 1399 Pfam PF00623 RNA polymerase Rpb1, domain 2 340 392 3.5E-8 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18470 283c76b9d5baaf510b1b6e678e7e7f2c 1399 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 16 1036 0.0 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18470 283c76b9d5baaf510b1b6e678e7e7f2c 1399 Pfam PF04983 RNA polymerase Rpb1, domain 3 485 640 3.7E-27 T 28-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS18470 283c76b9d5baaf510b1b6e678e7e7f2c 1399 Gene3D G3DSA:2.40.40.20 342 484 7.0E-40 T 28-03-2018 MKLM6_RS18470 283c76b9d5baaf510b1b6e678e7e7f2c 1399 SMART SM00663 231 510 1.4E-178 T 28-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MKLM6_RS20430 f2d272db1fb7a648ef07a9ee49395d65 423 SUPERFAMILY SSF103473 2 418 9.16E-29 T 28-03-2018 IPR020846 Major facilitator superfamily domain MKLM6_RS20430 f2d272db1fb7a648ef07a9ee49395d65 423 Gene3D G3DSA:1.20.1250.20 1 194 8.1E-13 T 28-03-2018 MKLM6_RS20430 f2d272db1fb7a648ef07a9ee49395d65 423 Pfam PF07690 Major Facilitator Superfamily 2 377 7.1E-14 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MKLM6_RS20430 f2d272db1fb7a648ef07a9ee49395d65 423 Gene3D G3DSA:1.20.1250.20 226 423 5.5E-14 T 28-03-2018 MKLM6_RS20610 4c5bd8437aeb4c67f063382d169a813a 439 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 204 296 4.0E-39 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MKLM6_RS20610 4c5bd8437aeb4c67f063382d169a813a 439 Gene3D G3DSA:3.40.50.720 1 201 3.0E-63 T 28-03-2018 MKLM6_RS20610 4c5bd8437aeb4c67f063382d169a813a 439 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 420 7.9E-144 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MKLM6_RS20610 4c5bd8437aeb4c67f063382d169a813a 439 SUPERFAMILY SSF52413 307 435 4.71E-39 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MKLM6_RS20610 4c5bd8437aeb4c67f063382d169a813a 439 Gene3D G3DSA:1.20.5.100 205 227 1.4E-14 T 28-03-2018 MKLM6_RS20610 4c5bd8437aeb4c67f063382d169a813a 439 SUPERFAMILY SSF48179 203 301 3.67E-35 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MKLM6_RS20610 4c5bd8437aeb4c67f063382d169a813a 439 SUPERFAMILY SSF51735 1 193 6.36E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS20610 4c5bd8437aeb4c67f063382d169a813a 439 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 186 4.3E-68 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MKLM6_RS20610 4c5bd8437aeb4c67f063382d169a813a 439 PIRSF PIRSF500134 1 439 2.0E-197 T 28-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 MKLM6_RS20610 4c5bd8437aeb4c67f063382d169a813a 439 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 320 423 8.7E-32 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MKLM6_RS20610 4c5bd8437aeb4c67f063382d169a813a 439 Gene3D G3DSA:3.40.50.720 228 436 6.7E-73 T 28-03-2018 MKLM6_RS20610 4c5bd8437aeb4c67f063382d169a813a 439 SMART SM00984 320 424 4.0E-50 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MKLM6_RS20610 4c5bd8437aeb4c67f063382d169a813a 439 PIRSF PIRSF000124 1 439 2.2E-157 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MKLM6_RS09075 3e202272ce49c99bb529426f9e4481eb 171 Gene3D G3DSA:3.30.230.60 7 167 2.4E-75 T 28-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 MKLM6_RS09075 3e202272ce49c99bb529426f9e4481eb 171 SUPERFAMILY SSF54211 4 167 9.1E-67 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS09075 3e202272ce49c99bb529426f9e4481eb 171 TIGRFAM TIGR03126 one_C_fae: formaldehyde-activating enzyme 7 166 2.9E-73 T 28-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 MKLM6_RS09075 3e202272ce49c99bb529426f9e4481eb 171 Pfam PF08714 Formaldehyde-activating enzyme (Fae) 9 166 6.2E-69 T 28-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 MKLM6_RS14140 3f7bb7ef2b2c63d56186949e0e4761ed 349 SUPERFAMILY SSF55103 186 345 1.86E-9 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MKLM6_RS14140 3f7bb7ef2b2c63d56186949e0e4761ed 349 Pfam PF01565 FAD binding domain 7 135 1.3E-18 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MKLM6_RS14140 3f7bb7ef2b2c63d56186949e0e4761ed 349 SUPERFAMILY SSF56176 7 173 2.76E-26 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MKLM6_RS14140 3f7bb7ef2b2c63d56186949e0e4761ed 349 Gene3D G3DSA:3.30.465.10 50 172 6.3E-25 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MKLM6_RS09480 d7e6c0791f5fe4ed39f2fc6e1aa4bb07 174 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 10 173 3.1E-68 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MKLM6_RS09480 d7e6c0791f5fe4ed39f2fc6e1aa4bb07 174 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 86 171 4.1E-36 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 MKLM6_RS09480 d7e6c0791f5fe4ed39f2fc6e1aa4bb07 174 ProSitePatterns PS00938 Initiation factor 3 signature. 61 74 - T 28-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 MKLM6_RS09480 d7e6c0791f5fe4ed39f2fc6e1aa4bb07 174 SUPERFAMILY SSF54364 8 81 6.93E-28 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MKLM6_RS09480 d7e6c0791f5fe4ed39f2fc6e1aa4bb07 174 Gene3D G3DSA:3.30.110.10 82 174 2.0E-34 T 28-03-2018 MKLM6_RS09480 d7e6c0791f5fe4ed39f2fc6e1aa4bb07 174 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 3 173 30.292 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MKLM6_RS09480 d7e6c0791f5fe4ed39f2fc6e1aa4bb07 174 Gene3D G3DSA:3.10.20.80 5 81 5.4E-30 T 28-03-2018 MKLM6_RS09480 d7e6c0791f5fe4ed39f2fc6e1aa4bb07 174 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 10 77 7.6E-30 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MKLM6_RS09480 d7e6c0791f5fe4ed39f2fc6e1aa4bb07 174 SUPERFAMILY SSF55200 86 174 1.02E-31 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 MKLM6_RS09290 5525430d81aef804febd82ef3fb1f942 349 Gene3D G3DSA:3.40.50.2000 128 296 1.4E-15 T 28-03-2018 MKLM6_RS09290 5525430d81aef804febd82ef3fb1f942 349 SUPERFAMILY SSF53756 20 306 1.99E-22 T 28-03-2018 MKLM6_RS09290 5525430d81aef804febd82ef3fb1f942 349 Pfam PF13524 Glycosyl transferases group 1 214 306 6.8E-11 T 28-03-2018 MKLM6_RS01785 c243e0df83157a127822d14e3cb0fefd 512 Pfam PF00990 Diguanylate cyclase, GGDEF domain 352 507 9.5E-44 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS01785 c243e0df83157a127822d14e3cb0fefd 512 Gene3D G3DSA:1.10.287.510 261 350 0.05 T 28-03-2018 MKLM6_RS01785 c243e0df83157a127822d14e3cb0fefd 512 Gene3D G3DSA:1.10.287.510 68 260 0.015 T 28-03-2018 MKLM6_RS01785 c243e0df83157a127822d14e3cb0fefd 512 Gene3D G3DSA:3.30.70.270 351 512 1.1E-52 T 28-03-2018 MKLM6_RS01785 c243e0df83157a127822d14e3cb0fefd 512 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 349 509 1.2E-47 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS01785 c243e0df83157a127822d14e3cb0fefd 512 SUPERFAMILY SSF55073 357 511 2.59E-46 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS01785 c243e0df83157a127822d14e3cb0fefd 512 SMART SM00267 341 512 3.4E-55 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS01790 ea908c7538c3fe18077c389cb943afd3 440 SMART SM00267 261 435 3.0E-51 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS01790 ea908c7538c3fe18077c389cb943afd3 440 Gene3D G3DSA:3.30.70.270 269 440 3.2E-53 T 28-03-2018 MKLM6_RS01790 ea908c7538c3fe18077c389cb943afd3 440 Pfam PF00990 Diguanylate cyclase, GGDEF domain 276 431 7.5E-46 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS01790 ea908c7538c3fe18077c389cb943afd3 440 SUPERFAMILY SSF55073 280 436 5.41E-49 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS01790 ea908c7538c3fe18077c389cb943afd3 440 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 274 434 1.4E-48 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS15535 6d625f0fa8bca5cc8b197093ffbe4dd5 99 Gene3D G3DSA:2.40.10.220 2 99 1.0E-10 T 28-03-2018 MKLM6_RS15535 6d625f0fa8bca5cc8b197093ffbe4dd5 99 SUPERFAMILY SSF141371 2 80 5.89E-6 T 28-03-2018 MKLM6_RS15535 6d625f0fa8bca5cc8b197093ffbe4dd5 99 Pfam PF07238 PilZ domain 6 89 3.5E-8 T 28-03-2018 IPR009875 PilZ domain GO:0035438 MKLM6_RS09930 5ae7107f7ae97c5e0c84dee12e15eb60 1035 Gene3D G3DSA:1.20.1640.10 288 504 5.9E-35 T 28-03-2018 MKLM6_RS09930 5ae7107f7ae97c5e0c84dee12e15eb60 1035 Gene3D G3DSA:1.20.1640.10 814 1030 2.0E-33 T 28-03-2018 MKLM6_RS09930 5ae7107f7ae97c5e0c84dee12e15eb60 1035 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1021 2.4E-276 T 28-03-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 MKLM6_RS09930 5ae7107f7ae97c5e0c84dee12e15eb60 1035 Pfam PF00873 AcrB/AcrD/AcrF family 6 1016 2.8E-253 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09930 5ae7107f7ae97c5e0c84dee12e15eb60 1035 SUPERFAMILY SSF82866 290 493 2.75E-33 T 28-03-2018 MKLM6_RS09930 5ae7107f7ae97c5e0c84dee12e15eb60 1035 SUPERFAMILY SSF82714 182 261 5.62E-16 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS09930 5ae7107f7ae97c5e0c84dee12e15eb60 1035 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 4.8E-27 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09930 5ae7107f7ae97c5e0c84dee12e15eb60 1035 PRINTS PR00702 Acriflavin resistance protein family signature 441 464 4.8E-27 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09930 5ae7107f7ae97c5e0c84dee12e15eb60 1035 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 4.8E-27 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09930 5ae7107f7ae97c5e0c84dee12e15eb60 1035 PRINTS PR00702 Acriflavin resistance protein family signature 540 557 4.8E-27 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09930 5ae7107f7ae97c5e0c84dee12e15eb60 1035 PRINTS PR00702 Acriflavin resistance protein family signature 466 489 4.8E-27 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09930 5ae7107f7ae97c5e0c84dee12e15eb60 1035 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 4.8E-27 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09930 5ae7107f7ae97c5e0c84dee12e15eb60 1035 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 4.8E-27 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09930 5ae7107f7ae97c5e0c84dee12e15eb60 1035 SUPERFAMILY SSF82866 798 1020 1.7E-42 T 28-03-2018 MKLM6_RS09930 5ae7107f7ae97c5e0c84dee12e15eb60 1035 Gene3D G3DSA:3.30.70.1430 42 134 2.6E-18 T 28-03-2018 MKLM6_RS09930 5ae7107f7ae97c5e0c84dee12e15eb60 1035 SUPERFAMILY SSF82714 711 793 1.31E-13 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS09930 5ae7107f7ae97c5e0c84dee12e15eb60 1035 Gene3D G3DSA:3.30.2090.10 179 266 7.1E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS09930 5ae7107f7ae97c5e0c84dee12e15eb60 1035 SUPERFAMILY SSF82693 42 127 2.2E-19 T 28-03-2018 MKLM6_RS09930 5ae7107f7ae97c5e0c84dee12e15eb60 1035 Gene3D G3DSA:3.30.2090.10 710 798 7.0E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS09930 5ae7107f7ae97c5e0c84dee12e15eb60 1035 Gene3D G3DSA:3.30.70.1430 555 657 1.3E-16 T 28-03-2018 MKLM6_RS09930 5ae7107f7ae97c5e0c84dee12e15eb60 1035 SUPERFAMILY SSF82693 554 654 2.46E-10 T 28-03-2018 MKLM6_RS09930 5ae7107f7ae97c5e0c84dee12e15eb60 1035 SUPERFAMILY SSF82693 137 180 1.26E-15 T 28-03-2018 MKLM6_RS09930 5ae7107f7ae97c5e0c84dee12e15eb60 1035 SUPERFAMILY SSF82693 266 324 1.26E-15 T 28-03-2018 MKLM6_RS18125 8bb0f933e2dd4672ecd9c7c8118ef860 188 Pfam PF01713 Smr domain 95 176 9.8E-25 T 28-03-2018 IPR002625 Smr domain MKLM6_RS18125 8bb0f933e2dd4672ecd9c7c8118ef860 188 SUPERFAMILY SSF160443 93 176 2.75E-18 T 28-03-2018 IPR002625 Smr domain MKLM6_RS18125 8bb0f933e2dd4672ecd9c7c8118ef860 188 SMART SM00463 92 176 1.5E-14 T 28-03-2018 IPR002625 Smr domain MKLM6_RS17725 59783e851dd9447bb4b977627d2ef46c 605 SUPERFAMILY SSF90123 27 324 5.89E-42 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MKLM6_RS17725 59783e851dd9447bb4b977627d2ef46c 605 SUPERFAMILY SSF90123 501 516 5.89E-42 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MKLM6_RS17725 59783e851dd9447bb4b977627d2ef46c 605 Pfam PF00005 ABC transporter 377 525 8.3E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS17725 59783e851dd9447bb4b977627d2ef46c 605 Pfam PF00664 ABC transporter transmembrane region 38 309 5.5E-16 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MKLM6_RS17725 59783e851dd9447bb4b977627d2ef46c 605 SUPERFAMILY SSF52540 351 595 2.19E-89 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS17725 59783e851dd9447bb4b977627d2ef46c 605 ProSitePatterns PS00211 ABC transporters family signature. 497 511 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS17725 59783e851dd9447bb4b977627d2ef46c 605 SMART SM00382 385 571 1.3E-20 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS17725 59783e851dd9447bb4b977627d2ef46c 605 Gene3D G3DSA:3.40.50.300 348 598 5.3E-75 T 28-03-2018 MKLM6_RS17725 59783e851dd9447bb4b977627d2ef46c 605 Gene3D G3DSA:1.20.1560.10 20 347 2.6E-35 T 28-03-2018 MKLM6_RS20190 9f5ad35fe51f92d63ff96b9b05167e46 313 SUPERFAMILY SSF56770 3 270 7.51E-68 T 28-03-2018 MKLM6_RS20190 9f5ad35fe51f92d63ff96b9b05167e46 313 PIRSF PIRSF000310 1 312 5.1E-75 T 28-03-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 MKLM6_RS20190 9f5ad35fe51f92d63ff96b9b05167e46 313 Gene3D G3DSA:3.40.50.700 1 192 8.6E-40 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS20190 9f5ad35fe51f92d63ff96b9b05167e46 313 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 12 173 3.3E-30 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS20190 9f5ad35fe51f92d63ff96b9b05167e46 313 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 193 270 2.9E-23 T 28-03-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal MKLM6_RS20190 9f5ad35fe51f92d63ff96b9b05167e46 313 Gene3D G3DSA:4.10.480.10 193 271 4.1E-22 T 28-03-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal MKLM6_RS20190 9f5ad35fe51f92d63ff96b9b05167e46 313 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 218 244 3.4E-7 T 28-03-2018 MKLM6_RS20190 9f5ad35fe51f92d63ff96b9b05167e46 313 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 245 258 3.4E-7 T 28-03-2018 MKLM6_RS20190 9f5ad35fe51f92d63ff96b9b05167e46 313 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 97 111 3.4E-7 T 28-03-2018 MKLM6_RS19170 434b7b2c3192dfcd73fa660d3709ffc3 415 Gene3D G3DSA:1.20.1250.20 2 203 2.1E-25 T 28-03-2018 MKLM6_RS19170 434b7b2c3192dfcd73fa660d3709ffc3 415 Pfam PF07690 Major Facilitator Superfamily 19 286 3.2E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MKLM6_RS19170 434b7b2c3192dfcd73fa660d3709ffc3 415 SUPERFAMILY SSF103473 8 405 1.96E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain MKLM6_RS19170 434b7b2c3192dfcd73fa660d3709ffc3 415 Gene3D G3DSA:1.20.1250.20 217 409 7.7E-27 T 28-03-2018 MKLM6_RS17695 b89f2db3d5413edb057f7f71c57f04fc 243 Pfam PF09347 Domain of unknown function (DUF1989) 15 187 6.5E-55 T 28-03-2018 IPR018959 Domain of unknown function DUF1989 MKLM6_RS17695 b89f2db3d5413edb057f7f71c57f04fc 243 TIGRFAM TIGR03425 urea_degr_2: urea carboxylase-associated protein 2 11 242 2.0E-107 T 28-03-2018 IPR017792 Urea carboxylase-associated protein 2 MKLM6_RS18155 8931e46d70aecf64530b779f6b6f405e 306 Pfam PF03466 LysR substrate binding domain 95 301 6.7E-29 T 28-03-2018 IPR005119 LysR, substrate-binding MKLM6_RS18155 8931e46d70aecf64530b779f6b6f405e 306 SUPERFAMILY SSF46785 5 85 1.36E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS18155 8931e46d70aecf64530b779f6b6f405e 306 Gene3D G3DSA:1.10.10.10 2 89 9.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS18155 8931e46d70aecf64530b779f6b6f405e 306 Gene3D G3DSA:3.40.190.10 184 273 9.3E-21 T 28-03-2018 MKLM6_RS18155 8931e46d70aecf64530b779f6b6f405e 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 4.3E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS18155 8931e46d70aecf64530b779f6b6f405e 306 Gene3D G3DSA:3.40.190.10 95 183 1.7E-15 T 28-03-2018 MKLM6_RS18155 8931e46d70aecf64530b779f6b6f405e 306 SUPERFAMILY SSF53850 91 299 3.14E-50 T 28-03-2018 MKLM6_RS16945 7999dfa24b1cd41b38c744734db0a23f 387 Gene3D G3DSA:1.10.3210.10 104 307 1.8E-29 T 28-03-2018 MKLM6_RS16945 7999dfa24b1cd41b38c744734db0a23f 387 Pfam PF13487 HD domain 193 254 7.3E-15 T 28-03-2018 MKLM6_RS16945 7999dfa24b1cd41b38c744734db0a23f 387 Pfam PF11871 Domain of unknown function (DUF3391) 6 80 5.0E-19 T 28-03-2018 IPR021812 Protein of unknown function DUF3391 MKLM6_RS16945 7999dfa24b1cd41b38c744734db0a23f 387 SUPERFAMILY SSF109604 145 303 1.52E-19 T 28-03-2018 MKLM6_RS08555 c817ef095c4c22c995515a616531710c 427 Gene3D G3DSA:1.10.287.620 82 394 0.0036 T 28-03-2018 MKLM6_RS08555 c817ef095c4c22c995515a616531710c 427 Pfam PF09903 Uncharacterized protein conserved in bacteria (DUF2130) 173 417 3.1E-73 T 28-03-2018 IPR019219 Protein of unknown function DUF2130 MKLM6_RS12885 29ebdcc8c98e08f4042170d1d2552b6b 365 Pfam PF03462 PCRF domain 32 220 4.6E-55 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 MKLM6_RS12885 29ebdcc8c98e08f4042170d1d2552b6b 365 SMART SM00937 85 195 1.1E-52 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 MKLM6_RS12885 29ebdcc8c98e08f4042170d1d2552b6b 365 SUPERFAMILY SSF75620 4 364 6.02E-134 T 28-03-2018 MKLM6_RS12885 29ebdcc8c98e08f4042170d1d2552b6b 365 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 3 365 39.678 T 28-03-2018 IPR020853 Peptide chain release factor 2, bacterial GO:0005737|GO:0006415|GO:0016149 MKLM6_RS12885 29ebdcc8c98e08f4042170d1d2552b6b 365 Gene3D G3DSA:3.30.160.20 226 307 4.5E-33 T 28-03-2018 MKLM6_RS12885 29ebdcc8c98e08f4042170d1d2552b6b 365 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 245 261 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MKLM6_RS12885 29ebdcc8c98e08f4042170d1d2552b6b 365 Pfam PF00472 RF-1 domain 228 337 3.2E-39 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MKLM6_RS12885 29ebdcc8c98e08f4042170d1d2552b6b 365 Gene3D G3DSA:1.20.58.410 3 116 3.1E-22 T 28-03-2018 MKLM6_RS12885 29ebdcc8c98e08f4042170d1d2552b6b 365 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 4 363 3.7E-162 T 28-03-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 MKLM6_RS11875 33ec3a67054a9a647b198f5d146dd8b8 232 SMART SM00382 35 223 2.8E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS11875 33ec3a67054a9a647b198f5d146dd8b8 232 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS11875 33ec3a67054a9a647b198f5d146dd8b8 232 Pfam PF00005 ABC transporter 26 174 1.4E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS11875 33ec3a67054a9a647b198f5d146dd8b8 232 TIGRFAM TIGR02211 LolD_lipo_ex: lipoprotein releasing system, ATP-binding protein 6 224 2.6E-103 T 28-03-2018 IPR011924 Lipoprotein releasing system, ATP-binding protein GO:0005524|GO:0006810|GO:0016020 MKLM6_RS11875 33ec3a67054a9a647b198f5d146dd8b8 232 SUPERFAMILY SSF52540 6 229 4.18E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS11875 33ec3a67054a9a647b198f5d146dd8b8 232 Gene3D G3DSA:3.40.50.300 2 232 1.5E-64 T 28-03-2018 MKLM6_RS01370 e2eb54e608c7bb807d2b24a611b385ce 366 Pfam PF13795 HupE / UreJ protein 189 337 1.6E-48 T 28-03-2018 IPR032809 Putative HupE/UreJ protein MKLM6_RS05790 fbe0e5fcf0618cb220dbbb548cf90757 160 SUPERFAMILY SSF52833 35 154 5.25E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS05790 fbe0e5fcf0618cb220dbbb548cf90757 160 Pfam PF00578 AhpC/TSA family 42 139 3.2E-11 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MKLM6_RS05790 fbe0e5fcf0618cb220dbbb548cf90757 160 Gene3D G3DSA:3.40.30.10 24 154 8.5E-20 T 28-03-2018 MKLM6_RS06530 ed92564a78a949cd344e709d3a254567 356 TIGRFAM TIGR04043 rSAM_MSMEG_0568: radical SAM protein, MSMEG_0568 family 3 355 2.2E-175 T 28-03-2018 IPR016779 Radical SAM enzyme, MSMEG0568 MKLM6_RS06530 ed92564a78a949cd344e709d3a254567 356 PIRSF PIRSF020870 1 356 1.4E-169 T 28-03-2018 IPR016779 Radical SAM enzyme, MSMEG0568 MKLM6_RS06530 ed92564a78a949cd344e709d3a254567 356 SUPERFAMILY SSF102114 125 330 9.55E-32 T 28-03-2018 MKLM6_RS06530 ed92564a78a949cd344e709d3a254567 356 Pfam PF04055 Radical SAM superfamily 125 282 5.4E-12 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS06530 ed92564a78a949cd344e709d3a254567 356 SMART SM00729 111 326 7.2E-4 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MKLM6_RS06530 ed92564a78a949cd344e709d3a254567 356 Gene3D G3DSA:3.20.20.70 107 355 3.3E-28 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS21795 027909fe3643efe0019c72cdbb8b4500 357 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 357 77.478 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 MKLM6_RS21795 027909fe3643efe0019c72cdbb8b4500 357 Gene3D G3DSA:3.40.50.300 1 351 6.2E-28 T 28-03-2018 MKLM6_RS21795 027909fe3643efe0019c72cdbb8b4500 357 Pfam PF02463 RecF/RecN/SMC N terminal domain 5 329 4.8E-26 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal MKLM6_RS21795 027909fe3643efe0019c72cdbb8b4500 357 SUPERFAMILY SSF52540 1 338 1.25E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS21795 027909fe3643efe0019c72cdbb8b4500 357 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 MKLM6_RS21795 027909fe3643efe0019c72cdbb8b4500 357 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 352 3.6E-90 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 MKLM6_RS13655 8fda5462a3b2557dfbcb5f2e8e3622ff 175 PRINTS PR00502 NUDIX hydrolase family signature 47 62 4.0E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MKLM6_RS13655 8fda5462a3b2557dfbcb5f2e8e3622ff 175 PRINTS PR00502 NUDIX hydrolase family signature 33 47 4.0E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MKLM6_RS13655 8fda5462a3b2557dfbcb5f2e8e3622ff 175 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MKLM6_RS13655 8fda5462a3b2557dfbcb5f2e8e3622ff 175 SUPERFAMILY SSF55811 5 151 5.15E-32 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MKLM6_RS13655 8fda5462a3b2557dfbcb5f2e8e3622ff 175 Gene3D G3DSA:3.90.79.10 1 163 7.9E-35 T 28-03-2018 MKLM6_RS13655 8fda5462a3b2557dfbcb5f2e8e3622ff 175 Pfam PF00293 NUDIX domain 7 144 1.1E-26 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MKLM6_RS13655 8fda5462a3b2557dfbcb5f2e8e3622ff 175 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 156 35.662 T 28-03-2018 IPR022927 RNA pyrophosphohydrolase RppH MKLM6_RS18725 812b3af813e079245ee5e68b32b68257 426 SUPERFAMILY SSF116734 202 414 4.58E-34 T 28-03-2018 MKLM6_RS18725 812b3af813e079245ee5e68b32b68257 426 Gene3D G3DSA:3.90.220.20 2 173 1.5E-27 T 28-03-2018 MKLM6_RS18725 812b3af813e079245ee5e68b32b68257 426 Gene3D G3DSA:3.90.220.20 174 392 1.3E-30 T 28-03-2018 MKLM6_RS18725 812b3af813e079245ee5e68b32b68257 426 Pfam PF01420 Type I restriction modification DNA specificity domain 11 178 9.9E-13 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MKLM6_RS18725 812b3af813e079245ee5e68b32b68257 426 Pfam PF01420 Type I restriction modification DNA specificity domain 210 395 8.0E-10 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MKLM6_RS18725 812b3af813e079245ee5e68b32b68257 426 SUPERFAMILY SSF116734 7 197 4.58E-40 T 28-03-2018 MKLM6_RS18445 b03e3c7b671cb82af26878cc22a9b326 103 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 2.7E-16 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18445 b03e3c7b671cb82af26878cc22a9b326 103 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 2.7E-16 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18445 b03e3c7b671cb82af26878cc22a9b326 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 2.7E-16 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18445 b03e3c7b671cb82af26878cc22a9b326 103 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 9.0E-35 T 28-03-2018 IPR027486 Ribosomal protein S10 domain MKLM6_RS18445 b03e3c7b671cb82af26878cc22a9b326 103 SUPERFAMILY SSF54999 6 102 7.59E-37 T 28-03-2018 IPR027486 Ribosomal protein S10 domain MKLM6_RS18445 b03e3c7b671cb82af26878cc22a9b326 103 SMART SM01403 7 101 9.6E-57 T 28-03-2018 IPR027486 Ribosomal protein S10 domain MKLM6_RS18445 b03e3c7b671cb82af26878cc22a9b326 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 4.2E-45 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18445 b03e3c7b671cb82af26878cc22a9b326 103 Gene3D G3DSA:3.30.70.600 3 103 3.9E-36 T 28-03-2018 IPR027486 Ribosomal protein S10 domain MKLM6_RS18445 b03e3c7b671cb82af26878cc22a9b326 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 28-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18445 b03e3c7b671cb82af26878cc22a9b326 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 26.562 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS19560 3fbdb135dc59c9c7ca17cfdb58ff24af 539 SUPERFAMILY SSF52540 28 222 7.84E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS19560 3fbdb135dc59c9c7ca17cfdb58ff24af 539 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 354 3.1E-130 T 28-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 MKLM6_RS19560 3fbdb135dc59c9c7ca17cfdb58ff24af 539 Pfam PF12170 DNA polymerase III tau subunit V interacting with alpha 410 532 2.2E-16 T 28-03-2018 IPR021029 DNA polymerase III, tau subunit, domain V GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS19560 3fbdb135dc59c9c7ca17cfdb58ff24af 539 Gene3D G3DSA:3.40.50.300 1 166 1.8E-38 T 28-03-2018 MKLM6_RS19560 3fbdb135dc59c9c7ca17cfdb58ff24af 539 Gene3D G3DSA:1.20.272.10 243 361 1.8E-15 T 28-03-2018 MKLM6_RS19560 3fbdb135dc59c9c7ca17cfdb58ff24af 539 SMART SM00382 37 179 2.9E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS19560 3fbdb135dc59c9c7ca17cfdb58ff24af 539 Gene3D G3DSA:1.10.8.60 167 242 5.5E-20 T 28-03-2018 MKLM6_RS19560 3fbdb135dc59c9c7ca17cfdb58ff24af 539 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 2.7E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 MKLM6_RS19560 3fbdb135dc59c9c7ca17cfdb58ff24af 539 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 2.7E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 MKLM6_RS19560 3fbdb135dc59c9c7ca17cfdb58ff24af 539 SUPERFAMILY SSF48019 246 361 5.44E-27 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MKLM6_RS19560 3fbdb135dc59c9c7ca17cfdb58ff24af 539 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 232 359 7.0E-27 T 28-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 MKLM6_RS19560 3fbdb135dc59c9c7ca17cfdb58ff24af 539 Pfam PF13177 DNA polymerase III, delta subunit 20 178 7.7E-42 T 28-03-2018 MKLM6_RS21890 df66fef504e62f6d5ad1b8f9dd2977e4 160 Pfam PF00589 Phage integrase family 24 140 4.0E-5 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS21890 df66fef504e62f6d5ad1b8f9dd2977e4 160 SUPERFAMILY SSF56349 33 143 3.83E-11 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS21890 df66fef504e62f6d5ad1b8f9dd2977e4 160 Gene3D G3DSA:1.10.443.10 13 145 2.4E-10 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS15465 67b489844b4547223a5642d98cc54e84 385 Gene3D G3DSA:2.40.50.100 57 225 1.3E-13 T 28-03-2018 MKLM6_RS15465 67b489844b4547223a5642d98cc54e84 385 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 55 283 3.8E-17 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MKLM6_RS15465 67b489844b4547223a5642d98cc54e84 385 Pfam PF00529 HlyD membrane-fusion protein of T1SS 31 335 7.5E-11 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MKLM6_RS15465 67b489844b4547223a5642d98cc54e84 385 SUPERFAMILY SSF111369 51 103 1.07E-10 T 28-03-2018 MKLM6_RS15465 67b489844b4547223a5642d98cc54e84 385 SUPERFAMILY SSF111369 188 266 1.07E-10 T 28-03-2018 MKLM6_RS15465 67b489844b4547223a5642d98cc54e84 385 SUPERFAMILY SSF111369 132 155 1.07E-10 T 28-03-2018 MKLM6_RS15465 67b489844b4547223a5642d98cc54e84 385 Gene3D G3DSA:2.40.50.100 226 376 1.1E-5 T 28-03-2018 MKLM6_RS21340 8ca65e7a295613dc53204beca57925ae 195 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 2 192 36.095 T 28-03-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 MKLM6_RS21340 8ca65e7a295613dc53204beca57925ae 195 Gene3D G3DSA:3.40.50.10490 2 193 8.4E-37 T 28-03-2018 MKLM6_RS21340 8ca65e7a295613dc53204beca57925ae 195 Pfam PF13580 SIS domain 11 146 1.0E-33 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MKLM6_RS21340 8ca65e7a295613dc53204beca57925ae 195 SUPERFAMILY SSF53697 3 193 1.72E-54 T 28-03-2018 MKLM6_RS02820 e3953986d62818c50b584bb337eb62c0 268 Pfam PF00535 Glycosyl transferase family 2 18 130 2.7E-17 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MKLM6_RS02820 e3953986d62818c50b584bb337eb62c0 268 Gene3D G3DSA:3.90.550.10 3 259 6.3E-24 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS02820 e3953986d62818c50b584bb337eb62c0 268 SUPERFAMILY SSF53448 14 171 1.69E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS11255 5d93e63edc20a93a971f528d3eb2ada8 306 SUPERFAMILY SSF53335 44 184 5.63E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS11255 5d93e63edc20a93a971f528d3eb2ada8 306 Pfam PF08241 Methyltransferase domain 53 146 3.2E-23 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MKLM6_RS11255 5d93e63edc20a93a971f528d3eb2ada8 306 Gene3D G3DSA:3.40.50.150 34 204 9.1E-33 T 28-03-2018 MKLM6_RS18380 ad3b427c9764c3e64989a5325dc58c0c 179 PIRSF PIRSF002161 1 179 5.1E-65 T 28-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18380 ad3b427c9764c3e64989a5325dc58c0c 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 43.58 T 28-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18380 ad3b427c9764c3e64989a5325dc58c0c 179 Gene3D G3DSA:3.30.1440.10 1 179 9.6E-78 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18380 ad3b427c9764c3e64989a5325dc58c0c 179 Pfam PF00281 Ribosomal protein L5 25 80 3.1E-26 T 28-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18380 ad3b427c9764c3e64989a5325dc58c0c 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 28-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18380 ad3b427c9764c3e64989a5325dc58c0c 179 SUPERFAMILY SSF55282 3 179 9.65E-78 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18380 ad3b427c9764c3e64989a5325dc58c0c 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 4.9E-41 T 28-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 Pfam PF01568 Molydopterin dinucleotide binding domain 810 914 1.3E-28 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 101 140 1.2E-15 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 Gene3D G3DSA:3.40.228.10 398 494 5.6E-18 T 28-03-2018 MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 238 288 2.7E-14 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 Gene3D G3DSA:3.40.50.740 495 778 6.0E-78 T 28-03-2018 MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 242 918 2.4E-283 T 28-03-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 Gene3D G3DSA:3.30.70.20 122 176 0.0054 T 28-03-2018 MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 Gene3D G3DSA:3.30.70.20 212 232 0.0018 T 28-03-2018 MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 SUPERFAMILY SSF54862 94 232 1.3E-37 T 28-03-2018 MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 Gene3D G3DSA:3.10.20.30 16 121 1.5E-14 T 28-03-2018 IPR012675 Beta-grasp domain MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 SMART SM00926 237 291 1.1E-14 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 Gene3D G3DSA:3.40.50.740 296 397 4.7E-24 T 28-03-2018 MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 SUPERFAMILY SSF54292 20 92 8.56E-19 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 Gene3D G3DSA:2.20.25.90 233 295 4.7E-15 T 28-03-2018 MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 Gene3D G3DSA:3.30.70.20 177 211 3.7E-9 T 28-03-2018 MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 SMART SM00929 101 141 1.1E-17 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 210 221 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 Pfam PF00037 4Fe-4S binding domain 206 223 1.2E-5 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 SUPERFAMILY SSF50692 778 920 6.33E-42 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 18 94 1.6E-23 T 28-03-2018 MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 SUPERFAMILY SSF53706 237 767 1.1E-189 T 28-03-2018 MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 Gene3D G3DSA:2.40.40.20 792 941 1.3E-38 T 28-03-2018 MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 PIRSF PIRSF036643 15 948 0.0 T 28-03-2018 MKLM6_RS17645 2146a778aa842b1439e9855a1454800e 950 Pfam PF00384 Molybdopterin oxidoreductase 294 726 2.0E-76 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS21215 b649fb4291d2c9d5715a04912aa89df7 292 Gene3D G3DSA:1.20.120.330 38 135 3.7E-4 T 28-03-2018 MKLM6_RS10475 b649fb4291d2c9d5715a04912aa89df7 292 Gene3D G3DSA:1.20.120.330 38 135 3.7E-4 T 28-03-2018 MKLM6_RS15505 1b64ca544ead39286ff7b4456e1c7f05 387 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 146 159 1.5E-18 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MKLM6_RS15505 1b64ca544ead39286ff7b4456e1c7f05 387 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 66 77 1.5E-18 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MKLM6_RS15505 1b64ca544ead39286ff7b4456e1c7f05 387 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 119 136 1.5E-18 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MKLM6_RS15505 1b64ca544ead39286ff7b4456e1c7f05 387 Gene3D G3DSA:3.40.710.10 27 293 7.2E-59 T 28-03-2018 MKLM6_RS15505 1b64ca544ead39286ff7b4456e1c7f05 387 SUPERFAMILY SSF56601 14 279 8.53E-88 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MKLM6_RS15505 1b64ca544ead39286ff7b4456e1c7f05 387 Gene3D G3DSA:2.60.410.10 294 369 5.5E-17 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MKLM6_RS15505 1b64ca544ead39286ff7b4456e1c7f05 387 SUPERFAMILY SSF69189 279 371 1.2E-19 T 28-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MKLM6_RS15505 1b64ca544ead39286ff7b4456e1c7f05 387 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 32 258 7.1E-87 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 MKLM6_RS15505 1b64ca544ead39286ff7b4456e1c7f05 387 SMART SM00936 279 369 5.1E-24 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MKLM6_RS15505 1b64ca544ead39286ff7b4456e1c7f05 387 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 279 368 1.8E-16 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MKLM6_RS02370 29f2287fd0c59abcff14c5c41d2ed049 283 SUPERFAMILY SSF116734 43 257 3.92E-40 T 28-03-2018 MKLM6_RS02370 29f2287fd0c59abcff14c5c41d2ed049 283 Gene3D G3DSA:1.10.287.1120 212 273 1.6E-11 T 28-03-2018 MKLM6_RS02370 29f2287fd0c59abcff14c5c41d2ed049 283 Gene3D G3DSA:3.90.220.20 2 211 3.7E-33 T 28-03-2018 MKLM6_RS02370 29f2287fd0c59abcff14c5c41d2ed049 283 Pfam PF01420 Type I restriction modification DNA specificity domain 77 216 1.3E-6 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MKLM6_RS20530 fa1193217bb5e91e4f14c9abbdbc3a4b 483 Gene3D G3DSA:3.40.50.720 18 104 1.5E-18 T 28-03-2018 MKLM6_RS20530 fa1193217bb5e91e4f14c9abbdbc3a4b 483 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 16 474 44.001 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS20530 fa1193217bb5e91e4f14c9abbdbc3a4b 483 Pfam PF08245 Mur ligase middle domain 121 301 5.0E-25 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MKLM6_RS20530 fa1193217bb5e91e4f14c9abbdbc3a4b 483 Gene3D G3DSA:3.90.190.20 323 474 4.8E-40 T 28-03-2018 MKLM6_RS20530 fa1193217bb5e91e4f14c9abbdbc3a4b 483 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 18 468 2.3E-172 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS20530 fa1193217bb5e91e4f14c9abbdbc3a4b 483 SUPERFAMILY SSF53623 102 320 5.49E-70 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MKLM6_RS20530 fa1193217bb5e91e4f14c9abbdbc3a4b 483 Pfam PF02875 Mur ligase family, glutamate ligase domain 323 411 4.6E-22 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MKLM6_RS20530 fa1193217bb5e91e4f14c9abbdbc3a4b 483 Pfam PF01225 Mur ligase family, catalytic domain 18 115 5.4E-27 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MKLM6_RS20530 fa1193217bb5e91e4f14c9abbdbc3a4b 483 Gene3D G3DSA:3.40.1190.10 105 322 1.4E-48 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MKLM6_RS20530 fa1193217bb5e91e4f14c9abbdbc3a4b 483 SUPERFAMILY SSF51984 17 103 1.44E-29 T 28-03-2018 MKLM6_RS20530 fa1193217bb5e91e4f14c9abbdbc3a4b 483 SUPERFAMILY SSF53244 321 470 2.93E-48 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MKLM6_RS13300 d24511508fe716cca62d14f0327f90ad 286 PIRSF PIRSF009437 29 286 1.2E-90 T 28-03-2018 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 MKLM6_RS13300 d24511508fe716cca62d14f0327f90ad 286 SMART SM00900 172 273 1.9E-24 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 MKLM6_RS13300 d24511508fe716cca62d14f0327f90ad 286 TIGRFAM TIGR01938 nqrC: NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit 34 281 3.9E-79 T 28-03-2018 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 MKLM6_RS13300 d24511508fe716cca62d14f0327f90ad 286 Hamap MF_00427 Na(+)-translocating NADH-quinone reductase subunit C [nqrC]. 35 286 35.049 T 28-03-2018 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 MKLM6_RS13300 d24511508fe716cca62d14f0327f90ad 286 Pfam PF04205 FMN-binding domain 172 269 2.2E-14 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 MKLM6_RS18210 05a23f3ee11defe24cb083b7ced61e60 393 SUPERFAMILY SSF51695 19 369 1.54E-69 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MKLM6_RS18210 05a23f3ee11defe24cb083b7ced61e60 393 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 25 364 1.3E-47 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 MKLM6_RS18210 05a23f3ee11defe24cb083b7ced61e60 393 Gene3D G3DSA:3.20.20.190 5 375 2.0E-70 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MKLM6_RS02800 9429c2dc25b9c9d8c8df9e1b4f327c56 245 Gene3D G3DSA:2.40.50.180 128 222 1.0E-5 T 28-03-2018 MKLM6_RS02800 9429c2dc25b9c9d8c8df9e1b4f327c56 245 Pfam PF01584 CheW-like domain 108 242 1.5E-11 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS02800 9429c2dc25b9c9d8c8df9e1b4f327c56 245 SMART SM00260 104 241 0.001 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS02800 9429c2dc25b9c9d8c8df9e1b4f327c56 245 SUPERFAMILY SSF50341 102 242 1.96E-13 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS11700 e08d78abc7eda68b3a7fc2eab1ebe385 138 Gene3D G3DSA:1.10.260.40 77 134 6.1E-8 T 28-03-2018 MKLM6_RS11700 e08d78abc7eda68b3a7fc2eab1ebe385 138 SUPERFAMILY SSF143100 3 64 3.92E-14 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like MKLM6_RS11700 e08d78abc7eda68b3a7fc2eab1ebe385 138 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 5 65 2.1E-6 T 28-03-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system MKLM6_RS11700 e08d78abc7eda68b3a7fc2eab1ebe385 138 Gene3D G3DSA:3.30.2390.10 4 73 8.5E-13 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like MKLM6_RS11700 e08d78abc7eda68b3a7fc2eab1ebe385 138 SUPERFAMILY SSF47413 81 133 4.74E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MKLM6_RS13095 b752694fee73a3330a212b6db13a914c 689 Pfam PF02503 Polyphosphate kinase middle domain 127 329 1.4E-59 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 MKLM6_RS13095 b752694fee73a3330a212b6db13a914c 689 Gene3D G3DSA:3.30.870.10 327 507 8.9E-23 T 28-03-2018 MKLM6_RS13095 b752694fee73a3330a212b6db13a914c 689 Hamap MF_00347 Polyphosphate kinase [ppk]. 10 689 29.114 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MKLM6_RS13095 b752694fee73a3330a212b6db13a914c 689 PIRSF PIRSF015589 1 689 1.0E-274 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MKLM6_RS13095 b752694fee73a3330a212b6db13a914c 689 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 12 685 3.9E-287 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MKLM6_RS13095 b752694fee73a3330a212b6db13a914c 689 Pfam PF13090 Polyphosphate kinase C-terminal domain 339 684 1.5E-154 T 28-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 MKLM6_RS13095 b752694fee73a3330a212b6db13a914c 689 SUPERFAMILY SSF143724 115 321 2.75E-61 T 28-03-2018 MKLM6_RS13095 b752694fee73a3330a212b6db13a914c 689 SUPERFAMILY SSF140356 9 112 6.15E-36 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 MKLM6_RS13095 b752694fee73a3330a212b6db13a914c 689 SUPERFAMILY SSF56024 322 499 1.57E-57 T 28-03-2018 MKLM6_RS13095 b752694fee73a3330a212b6db13a914c 689 Gene3D G3DSA:3.30.1840.10 117 314 1.5E-59 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 MKLM6_RS13095 b752694fee73a3330a212b6db13a914c 689 SUPERFAMILY SSF56024 508 687 2.69E-70 T 28-03-2018 MKLM6_RS13095 b752694fee73a3330a212b6db13a914c 689 Pfam PF13089 Polyphosphate kinase N-terminal domain 12 117 1.9E-33 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 MKLM6_RS13095 b752694fee73a3330a212b6db13a914c 689 Gene3D G3DSA:1.20.58.310 14 116 1.4E-32 T 28-03-2018 MKLM6_RS13095 b752694fee73a3330a212b6db13a914c 689 Gene3D G3DSA:3.30.870.10 508 689 1.0E-37 T 28-03-2018 MKLM6_RS18850 2c03e7d0f45828fa588eb1b35a8b6fb5 376 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 26 372 3.0E-129 T 28-03-2018 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 MKLM6_RS18850 2c03e7d0f45828fa588eb1b35a8b6fb5 376 Pfam PF01098 Cell cycle protein 29 372 1.8E-110 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 MKLM6_RS18850 2c03e7d0f45828fa588eb1b35a8b6fb5 376 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 329 353 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 MKLM6_RS17705 880df5c99565ecd4514c92cda8b83f04 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 260 3.2E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MKLM6_RS17705 880df5c99565ecd4514c92cda8b83f04 269 SUPERFAMILY SSF161098 69 255 3.66E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MKLM6_RS17705 880df5c99565ecd4514c92cda8b83f04 269 Gene3D G3DSA:1.10.3720.10 22 265 9.4E-30 T 28-03-2018 MKLM6_RS22695 5fa2858c4ceef8219f7d7a3ce839d3e9 342 SUPERFAMILY SSF47823 30 105 4.32E-7 T 28-03-2018 IPR010998 Integrase, Lambda-type, N-terminal MKLM6_RS22695 5fa2858c4ceef8219f7d7a3ce839d3e9 342 Gene3D G3DSA:1.10.443.10 144 323 1.9E-37 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS22695 5fa2858c4ceef8219f7d7a3ce839d3e9 342 SUPERFAMILY SSF56349 141 322 5.42E-43 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS22695 5fa2858c4ceef8219f7d7a3ce839d3e9 342 Gene3D G3DSA:1.10.150.130 16 125 1.7E-13 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal MKLM6_RS22695 5fa2858c4ceef8219f7d7a3ce839d3e9 342 Pfam PF00589 Phage integrase family 147 313 4.2E-32 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS01160 a92ccece52f88c2237a47803648f1ba7 592 SUPERFAMILY SSF51735 261 527 1.45E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS01160 a92ccece52f88c2237a47803648f1ba7 592 Pfam PF13727 CoA-binding domain 45 219 7.6E-18 T 28-03-2018 MKLM6_RS01160 a92ccece52f88c2237a47803648f1ba7 592 Pfam PF02719 Polysaccharide biosynthesis protein 266 547 3.6E-119 T 28-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain MKLM6_RS01160 a92ccece52f88c2237a47803648f1ba7 592 SUPERFAMILY SSF51735 124 253 1.14E-16 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS01160 a92ccece52f88c2237a47803648f1ba7 592 Gene3D G3DSA:3.40.50.720 259 584 1.8E-66 T 28-03-2018 MKLM6_RS01160 a92ccece52f88c2237a47803648f1ba7 592 Gene3D G3DSA:3.40.50.720 122 247 1.2E-26 T 28-03-2018 MKLM6_RS06380 854c73ff9743601e067517621d20177e 201 TIGRFAM TIGR03481 HpnM: hopanoid biosynthesis associated membrane protein HpnM 17 200 2.9E-66 T 28-03-2018 IPR017842 Hopanoid biosynthesis-associated membrane protein HpnM MKLM6_RS06380 854c73ff9743601e067517621d20177e 201 Pfam PF05494 MlaC protein 35 192 6.0E-40 T 28-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC MKLM6_RS06380 854c73ff9743601e067517621d20177e 201 Gene3D G3DSA:3.10.450.50 65 166 1.7E-16 T 28-03-2018 MKLM6_RS06380 854c73ff9743601e067517621d20177e 201 PIRSF PIRSF004649 1 201 3.7E-42 T 28-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC MKLM6_RS18410 6bb32ae77f513fac2af3f788a67b7a68 223 Gene3D G3DSA:3.30.300.20 17 107 4.8E-28 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta MKLM6_RS18410 6bb32ae77f513fac2af3f788a67b7a68 223 SUPERFAMILY SSF54821 108 206 5.49E-41 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18410 6bb32ae77f513fac2af3f788a67b7a68 223 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 28-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18410 6bb32ae77f513fac2af3f788a67b7a68 223 SMART SM00322 60 125 6.8E-9 T 28-03-2018 IPR004087 K Homology domain GO:0003676 MKLM6_RS18410 6bb32ae77f513fac2af3f788a67b7a68 223 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 39.46 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 MKLM6_RS18410 6bb32ae77f513fac2af3f788a67b7a68 223 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 8.5E-96 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 MKLM6_RS18410 6bb32ae77f513fac2af3f788a67b7a68 223 SUPERFAMILY SSF54814 2 106 8.11E-38 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 MKLM6_RS18410 6bb32ae77f513fac2af3f788a67b7a68 223 Pfam PF07650 KH domain 38 111 6.0E-20 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18410 6bb32ae77f513fac2af3f788a67b7a68 223 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 5.9E-41 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18410 6bb32ae77f513fac2af3f788a67b7a68 223 Gene3D G3DSA:3.30.1140.32 108 207 3.5E-39 T 28-03-2018 MKLM6_RS03120 c66ba459634c07fa0e5bd27d0cb6ff5a 272 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 3 69 5.7E-27 T 28-03-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 MKLM6_RS03120 c66ba459634c07fa0e5bd27d0cb6ff5a 272 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 1 272 56.402 T 28-03-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 MKLM6_RS03120 c66ba459634c07fa0e5bd27d0cb6ff5a 272 Gene3D G3DSA:1.10.166.10 3 69 1.1E-28 T 28-03-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 MKLM6_RS03120 c66ba459634c07fa0e5bd27d0cb6ff5a 272 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 4 271 8.5E-141 T 28-03-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 MKLM6_RS03120 c66ba459634c07fa0e5bd27d0cb6ff5a 272 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 134 162 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MKLM6_RS03120 c66ba459634c07fa0e5bd27d0cb6ff5a 272 SUPERFAMILY SSF51161 2 256 3.47E-74 T 28-03-2018 IPR011004 Trimeric LpxA-like MKLM6_RS03120 c66ba459634c07fa0e5bd27d0cb6ff5a 272 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 175 209 1.3E-15 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS03120 c66ba459634c07fa0e5bd27d0cb6ff5a 272 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 133 166 0.0021 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS03120 c66ba459634c07fa0e5bd27d0cb6ff5a 272 Gene3D G3DSA:2.160.10.10 87 257 4.2E-35 T 28-03-2018 MKLM6_RS01470 8c6c1cf8d632f878550aa1c5aa56489f 194 SUPERFAMILY SSF53335 4 181 4.92E-49 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS01470 8c6c1cf8d632f878550aa1c5aa56489f 194 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 117 123 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MKLM6_RS01470 8c6c1cf8d632f878550aa1c5aa56489f 194 PIRSF PIRSF004553 4 184 3.7E-52 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 MKLM6_RS01470 8c6c1cf8d632f878550aa1c5aa56489f 194 Gene3D G3DSA:3.40.50.150 1 192 3.8E-37 T 28-03-2018 MKLM6_RS01470 8c6c1cf8d632f878550aa1c5aa56489f 194 Pfam PF03602 Conserved hypothetical protein 95 5 180 8.0E-56 T 28-03-2018 MKLM6_RS01470 8c6c1cf8d632f878550aa1c5aa56489f 194 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 3 182 9.7E-54 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 MKLM6_RS04765 9527dc9e663f31bd6223c31c2c6e4f4c 225 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 1 223 27.84 T 28-03-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MKLM6_RS04765 9527dc9e663f31bd6223c31c2c6e4f4c 225 SUPERFAMILY SSF75445 129 205 1.03E-19 T 28-03-2018 MKLM6_RS04765 9527dc9e663f31bd6223c31c2c6e4f4c 225 SUPERFAMILY SSF100950 2 146 6.9E-40 T 28-03-2018 MKLM6_RS04765 9527dc9e663f31bd6223c31c2c6e4f4c 225 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 49 217 1.5E-52 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MKLM6_RS04765 9527dc9e663f31bd6223c31c2c6e4f4c 225 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 4 219 7.6E-66 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MKLM6_RS04765 9527dc9e663f31bd6223c31c2c6e4f4c 225 Gene3D G3DSA:3.30.70.260 139 203 2.5E-21 T 28-03-2018 MKLM6_RS04765 9527dc9e663f31bd6223c31c2c6e4f4c 225 Gene3D G3DSA:3.40.50.1360 1 138 7.5E-39 T 28-03-2018 MKLM6_RS22690 1cf908a9d13614699c5fba1d60ceff07 727 Gene3D G3DSA:1.10.443.10 402 600 6.9E-19 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS22690 1cf908a9d13614699c5fba1d60ceff07 727 Gene3D G3DSA:1.10.150.130 245 371 3.3E-6 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal MKLM6_RS22690 1cf908a9d13614699c5fba1d60ceff07 727 Pfam PF00589 Phage integrase family 420 590 3.6E-6 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS22690 1cf908a9d13614699c5fba1d60ceff07 727 SUPERFAMILY SSF56349 251 594 3.53E-17 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS15390 a5da61943828f209cad4efac1af799b4 302 TIGRFAM TIGR03018 pepcterm_TyrKin: exopolysaccharide/PEP-CTERM locus tyrosine autokinase 73 281 2.7E-75 T 28-03-2018 MKLM6_RS15390 a5da61943828f209cad4efac1af799b4 302 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 104 297 2.1E-32 T 28-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 MKLM6_RS15390 a5da61943828f209cad4efac1af799b4 302 Pfam PF13614 AAA domain 120 255 4.8E-10 T 28-03-2018 IPR025669 AAA domain MKLM6_RS15390 a5da61943828f209cad4efac1af799b4 302 Gene3D G3DSA:3.40.50.300 108 291 3.9E-26 T 28-03-2018 MKLM6_RS15390 a5da61943828f209cad4efac1af799b4 302 SUPERFAMILY SSF52540 110 292 1.88E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS14765 794762edeb9f4a7b35635442ff068af7 921 Pfam PF12137 RNA polymerase recycling family C-terminal 562 920 7.6E-134 T 28-03-2018 IPR022737 RNA polymerase recycling, bacterial, C-terminal GO:0016817 MKLM6_RS14765 794762edeb9f4a7b35635442ff068af7 921 SMART SM00487 149 340 6.9E-17 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MKLM6_RS14765 794762edeb9f4a7b35635442ff068af7 921 Pfam PF00176 SNF2 family N-terminal domain 173 376 5.8E-12 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 MKLM6_RS14765 794762edeb9f4a7b35635442ff068af7 921 Gene3D G3DSA:3.40.50.10810 128 397 1.9E-23 T 28-03-2018 MKLM6_RS14765 794762edeb9f4a7b35635442ff068af7 921 Hamap MF_01821 RNA polymerase-associated protein RapA [rapA]. 2 921 26.828 T 28-03-2018 IPR023949 RNA polymerase-associated protein RapA GO:0006355 MKLM6_RS14765 794762edeb9f4a7b35635442ff068af7 921 SUPERFAMILY SSF52540 152 343 2.13E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS14765 794762edeb9f4a7b35635442ff068af7 921 Pfam PF00271 Helicase conserved C-terminal domain 457 557 1.1E-13 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS14765 794762edeb9f4a7b35635442ff068af7 921 SMART SM00490 473 557 3.8E-15 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS14765 794762edeb9f4a7b35635442ff068af7 921 Gene3D G3DSA:3.40.50.300 398 592 4.2E-22 T 28-03-2018 MKLM6_RS14765 794762edeb9f4a7b35635442ff068af7 921 SUPERFAMILY SSF52540 436 602 3.4E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS14765 794762edeb9f4a7b35635442ff068af7 921 SUPERFAMILY SSF52540 271 335 3.4E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS21625 5d3e0d25f5d3201551a5646ed2a1d1f3 227 SUPERFAMILY SSF51419 1 222 3.01E-75 T 28-03-2018 IPR029066 PLP-binding barrel MKLM6_RS21625 5d3e0d25f5d3201551a5646ed2a1d1f3 227 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 76 90 - T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein MKLM6_RS21625 5d3e0d25f5d3201551a5646ed2a1d1f3 227 PIRSF PIRSF004848 2 227 2.9E-65 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein MKLM6_RS21625 5d3e0d25f5d3201551a5646ed2a1d1f3 227 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 1 224 3.0E-68 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein MKLM6_RS21625 5d3e0d25f5d3201551a5646ed2a1d1f3 227 Pfam PF01168 Alanine racemase, N-terminal domain 25 225 4.9E-29 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MKLM6_RS21625 5d3e0d25f5d3201551a5646ed2a1d1f3 227 Gene3D G3DSA:3.20.20.10 2 227 1.3E-64 T 28-03-2018 IPR029066 PLP-binding barrel MKLM6_RS10705 d2eb5751628bc2b82052b092f423a4c8 436 Pfam PF00742 Homoserine dehydrogenase 137 315 8.7E-65 T 28-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MKLM6_RS10705 d2eb5751628bc2b82052b092f423a4c8 436 SUPERFAMILY SSF51735 2 158 2.45E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS10705 d2eb5751628bc2b82052b092f423a4c8 436 Gene3D G3DSA:3.30.360.10 158 298 2.4E-53 T 28-03-2018 MKLM6_RS10705 d2eb5751628bc2b82052b092f423a4c8 436 SUPERFAMILY SSF55021 353 423 1.02E-11 T 28-03-2018 MKLM6_RS10705 d2eb5751628bc2b82052b092f423a4c8 436 SUPERFAMILY SSF55347 137 302 1.83E-54 T 28-03-2018 MKLM6_RS10705 d2eb5751628bc2b82052b092f423a4c8 436 PIRSF PIRSF000098 1 435 1.2E-166 T 28-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MKLM6_RS10705 d2eb5751628bc2b82052b092f423a4c8 436 Pfam PF01842 ACT domain 354 420 1.3E-10 T 28-03-2018 IPR002912 ACT domain MKLM6_RS10705 d2eb5751628bc2b82052b092f423a4c8 436 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 1.6E-18 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 MKLM6_RS10705 d2eb5751628bc2b82052b092f423a4c8 436 Gene3D G3DSA:3.30.70.260 350 431 2.0E-19 T 28-03-2018 MKLM6_RS10705 d2eb5751628bc2b82052b092f423a4c8 436 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 28-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MKLM6_RS10705 d2eb5751628bc2b82052b092f423a4c8 436 Gene3D G3DSA:3.40.50.720 1 157 5.7E-33 T 28-03-2018 MKLM6_RS20165 f51d728e26f3fae9025773575a712d55 237 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 183 0.0035 T 28-03-2018 MKLM6_RS20165 f51d728e26f3fae9025773575a712d55 237 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MKLM6_RS20165 f51d728e26f3fae9025773575a712d55 237 SUPERFAMILY SSF51735 6 217 1.61E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS20165 f51d728e26f3fae9025773575a712d55 237 Gene3D G3DSA:3.40.50.720 4 226 6.4E-53 T 28-03-2018 MKLM6_RS20165 f51d728e26f3fae9025773575a712d55 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 215 4.9E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS20165 f51d728e26f3fae9025773575a712d55 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 4.9E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS20165 f51d728e26f3fae9025773575a712d55 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 4.9E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS20165 f51d728e26f3fae9025773575a712d55 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.9E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS20165 f51d728e26f3fae9025773575a712d55 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 4.9E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS20165 f51d728e26f3fae9025773575a712d55 237 Pfam PF00106 short chain dehydrogenase 7 186 7.1E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS19665 551ebf0d8397607081b2a5c73a6194fb 935 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 615 9.0E-210 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS19665 551ebf0d8397607081b2a5c73a6194fb 935 SUPERFAMILY SSF46589 868 932 6.28E-17 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 MKLM6_RS19665 551ebf0d8397607081b2a5c73a6194fb 935 Hamap MF_02004 Valine--tRNA ligase [valS]. 1 933 16.114 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MKLM6_RS19665 551ebf0d8397607081b2a5c73a6194fb 935 SUPERFAMILY SSF50677 188 355 1.44E-56 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MKLM6_RS19665 551ebf0d8397607081b2a5c73a6194fb 935 Pfam PF08264 Anticodon-binding domain of tRNA 658 809 9.9E-43 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 MKLM6_RS19665 551ebf0d8397607081b2a5c73a6194fb 935 SUPERFAMILY SSF47323 626 883 7.29E-70 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS19665 551ebf0d8397607081b2a5c73a6194fb 935 PRINTS PR00986 Valyl-tRNA synthetase signature 33 44 7.9E-39 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MKLM6_RS19665 551ebf0d8397607081b2a5c73a6194fb 935 PRINTS PR00986 Valyl-tRNA synthetase signature 490 508 7.9E-39 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MKLM6_RS19665 551ebf0d8397607081b2a5c73a6194fb 935 PRINTS PR00986 Valyl-tRNA synthetase signature 459 480 7.9E-39 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MKLM6_RS19665 551ebf0d8397607081b2a5c73a6194fb 935 PRINTS PR00986 Valyl-tRNA synthetase signature 359 372 7.9E-39 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MKLM6_RS19665 551ebf0d8397607081b2a5c73a6194fb 935 PRINTS PR00986 Valyl-tRNA synthetase signature 227 244 7.9E-39 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MKLM6_RS19665 551ebf0d8397607081b2a5c73a6194fb 935 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 868 933 5.2E-17 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 MKLM6_RS19665 551ebf0d8397607081b2a5c73a6194fb 935 Gene3D G3DSA:3.40.50.620 1 603 1.3E-138 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS19665 551ebf0d8397607081b2a5c73a6194fb 935 TIGRFAM TIGR00422 valS: valine--tRNA ligase 1 915 0.0 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MKLM6_RS19665 551ebf0d8397607081b2a5c73a6194fb 935 SUPERFAMILY SSF52374 1 189 4.12E-139 T 28-03-2018 MKLM6_RS19665 551ebf0d8397607081b2a5c73a6194fb 935 SUPERFAMILY SSF52374 354 555 4.12E-139 T 28-03-2018 MKLM6_RS19665 551ebf0d8397607081b2a5c73a6194fb 935 SUPERFAMILY SSF52374 593 625 4.12E-139 T 28-03-2018 MKLM6_RS19665 551ebf0d8397607081b2a5c73a6194fb 935 Gene3D G3DSA:1.10.730.10 604 774 1.3E-54 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS19665 551ebf0d8397607081b2a5c73a6194fb 935 Gene3D G3DSA:1.10.287.380 861 931 1.0E-25 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 MKLM6_RS19665 551ebf0d8397607081b2a5c73a6194fb 935 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 40 51 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS04190 34488cf9348f9b1582796d80c94e1244 144 Pfam PF01381 Helix-turn-helix 7 52 2.4E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MKLM6_RS04190 34488cf9348f9b1582796d80c94e1244 144 SMART SM00530 6 60 2.3E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MKLM6_RS04190 34488cf9348f9b1582796d80c94e1244 144 Gene3D G3DSA:1.10.260.40 2 142 7.7E-14 T 28-03-2018 MKLM6_RS04190 34488cf9348f9b1582796d80c94e1244 144 SUPERFAMILY SSF47413 1 64 4.02E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MKLM6_RS21770 63088fa6db0f2e3b29de67c85ee87481 415 Gene3D G3DSA:3.40.50.1820 17 386 3.2E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS21770 63088fa6db0f2e3b29de67c85ee87481 415 Pfam PF03283 Pectinacetylesterase 50 229 3.4E-18 T 28-03-2018 IPR004963 Pectinacetylesterase/NOTUM GO:0016787 Reactome: R-HSA-381426|Reactome: R-HSA-5362798|Reactome: R-HSA-8957275 MKLM6_RS08820 581f30ca3659e62276f9fb0a9fa2a933 246 Gene3D G3DSA:3.30.70.1070 183 239 0.024 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 MKLM6_RS12895 423a2ad90f44dd840d510613fe4d742d 320 Gene3D G3DSA:3.40.190.10 89 230 8.8E-8 T 28-03-2018 MKLM6_RS12895 423a2ad90f44dd840d510613fe4d742d 320 Gene3D G3DSA:1.10.10.10 1 86 1.4E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS12895 423a2ad90f44dd840d510613fe4d742d 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 6.1E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS12895 423a2ad90f44dd840d510613fe4d742d 320 Pfam PF03466 LysR substrate binding domain 90 293 1.3E-15 T 28-03-2018 IPR005119 LysR, substrate-binding MKLM6_RS12895 423a2ad90f44dd840d510613fe4d742d 320 SUPERFAMILY SSF46785 2 85 6.53E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS12895 423a2ad90f44dd840d510613fe4d742d 320 SUPERFAMILY SSF53850 90 292 6.7E-25 T 28-03-2018 MKLM6_RS11110 2829d9fe20ccc9880babe37b7376fc79 387 Gene3D G3DSA:3.90.1150.10 200 387 6.9E-46 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS11110 2829d9fe20ccc9880babe37b7376fc79 387 Gene3D G3DSA:3.90.1150.10 1 149 4.7E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS11110 2829d9fe20ccc9880babe37b7376fc79 387 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 231 244 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 MKLM6_RS11110 2829d9fe20ccc9880babe37b7376fc79 387 SUPERFAMILY SSF53383 4 385 2.13E-99 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS11110 2829d9fe20ccc9880babe37b7376fc79 387 Pfam PF00155 Aminotransferase class I and II 33 373 1.7E-57 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MKLM6_RS01975 5cdbadab2a0cbe6614acbaad9844efd4 159 Pfam PF01252 Signal peptidase (SPase) II 8 147 6.3E-41 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MKLM6_RS01975 5cdbadab2a0cbe6614acbaad9844efd4 159 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 93 108 1.0E-18 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MKLM6_RS01975 5cdbadab2a0cbe6614acbaad9844efd4 159 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 129 145 1.0E-18 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MKLM6_RS01975 5cdbadab2a0cbe6614acbaad9844efd4 159 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 45 53 1.0E-18 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MKLM6_RS01975 5cdbadab2a0cbe6614acbaad9844efd4 159 ProSitePatterns PS00855 Signal peptidases II signature. 96 108 - T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MKLM6_RS01975 5cdbadab2a0cbe6614acbaad9844efd4 159 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 154 16.464 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MKLM6_RS01975 5cdbadab2a0cbe6614acbaad9844efd4 159 TIGRFAM TIGR00077 lspA: signal peptidase II 2 149 5.3E-44 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MKLM6_RS10180 333e1f4944ae45696448e5adec2c4fb0 241 Gene3D G3DSA:1.25.40.10 130 239 1.7E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS10180 333e1f4944ae45696448e5adec2c4fb0 241 SUPERFAMILY SSF48452 137 235 4.11E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS16160 c5638a3a642ccfbe570b292c9d6fe43e 1026 Gene3D G3DSA:1.20.1640.10 287 499 1.3E-29 T 28-03-2018 MKLM6_RS16160 c5638a3a642ccfbe570b292c9d6fe43e 1026 SUPERFAMILY SSF82693 43 139 1.57E-18 T 28-03-2018 MKLM6_RS16160 c5638a3a642ccfbe570b292c9d6fe43e 1026 SUPERFAMILY SSF82714 707 792 4.97E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS16160 c5638a3a642ccfbe570b292c9d6fe43e 1026 Gene3D G3DSA:3.30.2090.10 184 270 8.0E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS16160 c5638a3a642ccfbe570b292c9d6fe43e 1026 Gene3D G3DSA:3.30.70.1430 556 658 2.4E-16 T 28-03-2018 MKLM6_RS16160 c5638a3a642ccfbe570b292c9d6fe43e 1026 Pfam PF00873 AcrB/AcrD/AcrF family 8 1007 1.6E-159 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16160 c5638a3a642ccfbe570b292c9d6fe43e 1026 SUPERFAMILY SSF82714 188 268 1.44E-10 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS16160 c5638a3a642ccfbe570b292c9d6fe43e 1026 SUPERFAMILY SSF82866 790 1012 3.92E-42 T 28-03-2018 MKLM6_RS16160 c5638a3a642ccfbe570b292c9d6fe43e 1026 Gene3D G3DSA:1.20.1640.10 800 1012 8.8E-33 T 28-03-2018 MKLM6_RS16160 c5638a3a642ccfbe570b292c9d6fe43e 1026 PRINTS PR00702 Acriflavin resistance protein family signature 359 380 5.4E-17 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16160 c5638a3a642ccfbe570b292c9d6fe43e 1026 PRINTS PR00702 Acriflavin resistance protein family signature 387 411 5.4E-17 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16160 c5638a3a642ccfbe570b292c9d6fe43e 1026 PRINTS PR00702 Acriflavin resistance protein family signature 41 59 5.4E-17 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16160 c5638a3a642ccfbe570b292c9d6fe43e 1026 PRINTS PR00702 Acriflavin resistance protein family signature 465 488 5.4E-17 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16160 c5638a3a642ccfbe570b292c9d6fe43e 1026 PRINTS PR00702 Acriflavin resistance protein family signature 440 463 5.4E-17 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS16160 c5638a3a642ccfbe570b292c9d6fe43e 1026 SUPERFAMILY SSF82693 271 326 5.75E-16 T 28-03-2018 MKLM6_RS16160 c5638a3a642ccfbe570b292c9d6fe43e 1026 SUPERFAMILY SSF82693 139 185 5.75E-16 T 28-03-2018 MKLM6_RS16160 c5638a3a642ccfbe570b292c9d6fe43e 1026 Gene3D G3DSA:3.30.70.1430 43 147 4.3E-30 T 28-03-2018 MKLM6_RS16160 c5638a3a642ccfbe570b292c9d6fe43e 1026 SUPERFAMILY SSF82866 298 492 3.01E-33 T 28-03-2018 MKLM6_RS16160 c5638a3a642ccfbe570b292c9d6fe43e 1026 Gene3D G3DSA:3.30.2090.10 706 793 2.6E-16 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS16160 c5638a3a642ccfbe570b292c9d6fe43e 1026 SUPERFAMILY SSF82693 556 642 6.8E-8 T 28-03-2018 MKLM6_RS18630 97cbc74710e27b987480bcdc92f52a66 513 Pfam PF00512 His Kinase A (phospho-acceptor) domain 294 357 2.5E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS18630 97cbc74710e27b987480bcdc92f52a66 513 SMART SM00387 402 507 8.7E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS18630 97cbc74710e27b987480bcdc92f52a66 513 Gene3D G3DSA:3.30.450.20 167 279 7.8E-5 T 28-03-2018 MKLM6_RS18630 97cbc74710e27b987480bcdc92f52a66 513 Gene3D G3DSA:1.10.287.130 283 356 1.8E-14 T 28-03-2018 MKLM6_RS18630 97cbc74710e27b987480bcdc92f52a66 513 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 468 5.9E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS18630 97cbc74710e27b987480bcdc92f52a66 513 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 454 5.9E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS18630 97cbc74710e27b987480bcdc92f52a66 513 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 487 5.9E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS18630 97cbc74710e27b987480bcdc92f52a66 513 Gene3D G3DSA:3.30.565.10 358 504 5.4E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS18630 97cbc74710e27b987480bcdc92f52a66 513 SUPERFAMILY SSF55874 388 503 1.7E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS18630 97cbc74710e27b987480bcdc92f52a66 513 Pfam PF13188 PAS domain 186 241 1.7E-4 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18630 97cbc74710e27b987480bcdc92f52a66 513 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 403 503 3.2E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS18630 97cbc74710e27b987480bcdc92f52a66 513 SMART SM00388 294 360 8.3E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS18630 97cbc74710e27b987480bcdc92f52a66 513 SUPERFAMILY SSF47384 288 357 4.9E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS12290 c94a2c463c2f80319de3d4743e9dcae4 1364 Gene3D G3DSA:3.40.50.980 659 820 9.3E-37 T 28-03-2018 MKLM6_RS12290 c94a2c463c2f80319de3d4743e9dcae4 1364 SUPERFAMILY SSF55469 997 1067 4.49E-13 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MKLM6_RS12290 c94a2c463c2f80319de3d4743e9dcae4 1364 SUPERFAMILY SSF55469 1094 1180 4.49E-13 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MKLM6_RS12290 c94a2c463c2f80319de3d4743e9dcae4 1364 Gene3D G3DSA:1.10.1200.10 1270 1363 5.0E-20 T 28-03-2018 MKLM6_RS12290 c94a2c463c2f80319de3d4743e9dcae4 1364 Gene3D G3DSA:3.30.300.30 909 1269 5.4E-31 T 28-03-2018 MKLM6_RS12290 c94a2c463c2f80319de3d4743e9dcae4 1364 SUPERFAMILY SSF52777 51 245 4.89E-27 T 28-03-2018 MKLM6_RS12290 c94a2c463c2f80319de3d4743e9dcae4 1364 Gene3D G3DSA:3.30.559.10 26 246 7.0E-25 T 28-03-2018 MKLM6_RS12290 c94a2c463c2f80319de3d4743e9dcae4 1364 SUPERFAMILY SSF56801 1200 1278 3.27E-137 T 28-03-2018 MKLM6_RS12290 c94a2c463c2f80319de3d4743e9dcae4 1364 SUPERFAMILY SSF56801 487 967 3.27E-137 T 28-03-2018 MKLM6_RS12290 c94a2c463c2f80319de3d4743e9dcae4 1364 SUPERFAMILY SSF52777 232 478 1.45E-48 T 28-03-2018 MKLM6_RS12290 c94a2c463c2f80319de3d4743e9dcae4 1364 SMART SM00823 Phosphopantetheine attachment site 1265 1335 0.0035 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MKLM6_RS12290 c94a2c463c2f80319de3d4743e9dcae4 1364 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 1035 1169 4.2E-23 T 28-03-2018 IPR020051 SagB-type dehydrogenase domain MKLM6_RS12290 c94a2c463c2f80319de3d4743e9dcae4 1364 ProSitePatterns PS00455 Putative AMP-binding domain signature. 654 665 - T 28-03-2018 IPR020845 AMP-binding, conserved site MKLM6_RS12290 c94a2c463c2f80319de3d4743e9dcae4 1364 Gene3D G3DSA:3.40.50.980 507 658 8.4E-39 T 28-03-2018 MKLM6_RS12290 c94a2c463c2f80319de3d4743e9dcae4 1364 PRINTS PR00154 AMP-binding signature 661 669 8.3E-5 T 28-03-2018 IPR020459 AMP-binding MKLM6_RS12290 c94a2c463c2f80319de3d4743e9dcae4 1364 PRINTS PR00154 AMP-binding signature 649 660 8.3E-5 T 28-03-2018 IPR020459 AMP-binding MKLM6_RS12290 c94a2c463c2f80319de3d4743e9dcae4 1364 Pfam PF00501 AMP-binding enzyme 515 912 4.4E-89 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MKLM6_RS12290 c94a2c463c2f80319de3d4743e9dcae4 1364 Gene3D G3DSA:2.30.38.10 824 903 7.1E-20 T 28-03-2018 MKLM6_RS12290 c94a2c463c2f80319de3d4743e9dcae4 1364 Pfam PF00881 Nitroreductase family 1003 1171 6.2E-9 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MKLM6_RS12290 c94a2c463c2f80319de3d4743e9dcae4 1364 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 535 936 4.9E-119 T 28-03-2018 IPR010071 Amino acid adenylation domain MKLM6_RS12290 c94a2c463c2f80319de3d4743e9dcae4 1364 Pfam PF00550 Phosphopantetheine attachment site 1266 1331 2.0E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS12290 c94a2c463c2f80319de3d4743e9dcae4 1364 SUPERFAMILY SSF47336 1260 1347 3.14E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS12290 c94a2c463c2f80319de3d4743e9dcae4 1364 Pfam PF00668 Condensation domain 55 494 3.9E-41 T 28-03-2018 IPR001242 Condensation domain MKLM6_RS18425 b0a4d9cdf6bf08e1c41677bcbab31804 275 SMART SM01382 124 252 1.9E-91 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18425 b0a4d9cdf6bf08e1c41677bcbab31804 275 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 4 273 6.6E-129 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 MKLM6_RS18425 b0a4d9cdf6bf08e1c41677bcbab31804 275 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 28-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18425 b0a4d9cdf6bf08e1c41677bcbab31804 275 Gene3D G3DSA:2.30.30.30 119 195 1.5E-29 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 MKLM6_RS18425 b0a4d9cdf6bf08e1c41677bcbab31804 275 SMART SM01383 42 118 2.1E-45 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18425 b0a4d9cdf6bf08e1c41677bcbab31804 275 Gene3D G3DSA:2.40.50.140 1 114 8.4E-46 T 28-03-2018 MKLM6_RS18425 b0a4d9cdf6bf08e1c41677bcbab31804 275 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 250 1.1E-56 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18425 b0a4d9cdf6bf08e1c41677bcbab31804 275 SUPERFAMILY SSF50104 126 272 1.02E-61 T 28-03-2018 IPR008991 Translation protein SH3-like domain MKLM6_RS18425 b0a4d9cdf6bf08e1c41677bcbab31804 275 SUPERFAMILY SSF50249 2 125 2.36E-47 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS18425 b0a4d9cdf6bf08e1c41677bcbab31804 275 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 2.3E-32 T 28-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18425 b0a4d9cdf6bf08e1c41677bcbab31804 275 PIRSF PIRSF002158 13 275 8.8E-101 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18425 b0a4d9cdf6bf08e1c41677bcbab31804 275 Gene3D G3DSA:4.10.950.10 197 273 3.0E-37 T 28-03-2018 IPR014726 Ribosomal protein L2, domain 3 MKLM6_RS18425 b0a4d9cdf6bf08e1c41677bcbab31804 275 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 46.362 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 MKLM6_RS11945 42b86a3c09302fa05f85ece154026a22 204 SUPERFAMILY SSF52980 11 179 8.58E-22 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MKLM6_RS11945 42b86a3c09302fa05f85ece154026a22 204 Gene3D G3DSA:3.90.1570.10 6 183 3.4E-40 T 28-03-2018 MKLM6_RS11945 42b86a3c09302fa05f85ece154026a22 204 Pfam PF05685 Putative restriction endonuclease 15 159 1.7E-29 T 28-03-2018 IPR008538 Domain of unknown function DUF820 MKLM6_RS16385 d4db26bc93c161e7a96a62a32490c740 304 SMART SM00849 49 232 1.3E-18 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS16385 d4db26bc93c161e7a96a62a32490c740 304 TIGRFAM TIGR04559 SoxH_rel_PQQ_2: quinoprotein relay system zinc metallohydrolase 2 22 303 1.0E-124 T 28-03-2018 IPR030829 Quinoprotein relay system zinc metallohydrolase 2 MKLM6_RS16385 d4db26bc93c161e7a96a62a32490c740 304 Pfam PF00753 Metallo-beta-lactamase superfamily 49 232 7.9E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS16385 d4db26bc93c161e7a96a62a32490c740 304 Gene3D G3DSA:3.60.15.10 45 303 1.4E-24 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS16385 d4db26bc93c161e7a96a62a32490c740 304 SUPERFAMILY SSF56281 8 287 1.82E-54 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS15160 88c9441825e5cca5daf2b2c0f7908411 508 Pfam PF13185 GAF domain 29 159 3.1E-10 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS15160 88c9441825e5cca5daf2b2c0f7908411 508 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 467 484 1.1E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS15160 88c9441825e5cca5daf2b2c0f7908411 508 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 484 504 1.1E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS15160 88c9441825e5cca5daf2b2c0f7908411 508 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 407 416 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site MKLM6_RS15160 88c9441825e5cca5daf2b2c0f7908411 508 SUPERFAMILY SSF52540 193 435 1.69E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS15160 88c9441825e5cca5daf2b2c0f7908411 508 Gene3D G3DSA:3.30.450.40 8 177 1.1E-16 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS15160 88c9441825e5cca5daf2b2c0f7908411 508 Pfam PF02954 Bacterial regulatory protein, Fis family 465 499 7.9E-11 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS15160 88c9441825e5cca5daf2b2c0f7908411 508 SMART SM00065 27 171 9.6E-12 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS15160 88c9441825e5cca5daf2b2c0f7908411 508 TIGRFAM TIGR01817 nifA: Nif-specific regulatory protein 10 508 9.6E-193 T 28-03-2018 IPR010113 Nif-specific regulatory protein GO:0003700|GO:0006355|GO:0009399 MKLM6_RS15160 88c9441825e5cca5daf2b2c0f7908411 508 SUPERFAMILY SSF55781 8 161 1.45E-17 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS15160 88c9441825e5cca5daf2b2c0f7908411 508 SMART SM00382 214 357 1.4E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS15160 88c9441825e5cca5daf2b2c0f7908411 508 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 218 231 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MKLM6_RS15160 88c9441825e5cca5daf2b2c0f7908411 508 Gene3D G3DSA:1.10.8.60 367 439 1.1E-21 T 28-03-2018 MKLM6_RS15160 88c9441825e5cca5daf2b2c0f7908411 508 Gene3D G3DSA:1.10.10.60 440 499 5.5E-7 T 28-03-2018 MKLM6_RS15160 88c9441825e5cca5daf2b2c0f7908411 508 Pfam PF00158 Sigma-54 interaction domain 194 360 8.2E-70 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MKLM6_RS15160 88c9441825e5cca5daf2b2c0f7908411 508 Gene3D G3DSA:3.40.50.300 189 366 2.4E-28 T 28-03-2018 MKLM6_RS15160 88c9441825e5cca5daf2b2c0f7908411 508 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 280 295 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MKLM6_RS20555 1e5c3c1e37e012b055f96883f8a8812e 385 SMART SM00864 13 205 2.1E-99 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MKLM6_RS20555 1e5c3c1e37e012b055f96883f8a8812e 385 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 362 35.939 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 MKLM6_RS20555 1e5c3c1e37e012b055f96883f8a8812e 385 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 3 323 9.8E-122 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 MKLM6_RS20555 1e5c3c1e37e012b055f96883f8a8812e 385 SMART SM00865 207 325 8.0E-49 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 MKLM6_RS20555 1e5c3c1e37e012b055f96883f8a8812e 385 SUPERFAMILY SSF52490 13 208 8.24E-66 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MKLM6_RS20555 1e5c3c1e37e012b055f96883f8a8812e 385 Gene3D G3DSA:3.30.1330.20 215 325 3.5E-42 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 MKLM6_RS20555 1e5c3c1e37e012b055f96883f8a8812e 385 SUPERFAMILY SSF55307 204 319 3.66E-39 T 28-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 MKLM6_RS20555 1e5c3c1e37e012b055f96883f8a8812e 385 Gene3D G3DSA:3.40.50.1440 7 214 6.5E-42 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MKLM6_RS20555 1e5c3c1e37e012b055f96883f8a8812e 385 Pfam PF12327 FtsZ family, C-terminal domain 222 316 1.5E-28 T 28-03-2018 IPR024757 Cell division protein FtsZ, C-terminal MKLM6_RS20555 1e5c3c1e37e012b055f96883f8a8812e 385 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 170 2.8E-37 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MKLM6_RS20555 1e5c3c1e37e012b055f96883f8a8812e 385 PRINTS PR00423 Cell division protein FtsZ signature 212 233 3.1E-47 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MKLM6_RS20555 1e5c3c1e37e012b055f96883f8a8812e 385 PRINTS PR00423 Cell division protein FtsZ signature 98 118 3.1E-47 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MKLM6_RS20555 1e5c3c1e37e012b055f96883f8a8812e 385 PRINTS PR00423 Cell division protein FtsZ signature 126 147 3.1E-47 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MKLM6_RS20555 1e5c3c1e37e012b055f96883f8a8812e 385 PRINTS PR00423 Cell division protein FtsZ signature 189 211 3.1E-47 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MKLM6_RS06305 699ab6205da6a8fefafd7582cd9c0faa 208 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 196 3.9E-53 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 MKLM6_RS06305 699ab6205da6a8fefafd7582cd9c0faa 208 SUPERFAMILY SSF52540 1 188 2.41E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS06305 699ab6205da6a8fefafd7582cd9c0faa 208 Gene3D G3DSA:3.40.50.300 1 196 4.6E-53 T 28-03-2018 MKLM6_RS06305 699ab6205da6a8fefafd7582cd9c0faa 208 Pfam PF02223 Thymidylate kinase 9 196 1.7E-52 T 28-03-2018 MKLM6_RS06305 699ab6205da6a8fefafd7582cd9c0faa 208 Hamap MF_00165 Thymidylate kinase [tmk]. 5 206 29.359 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 MKLM6_RS19290 d83366a71864bb2f276151137bcbac02 369 PIRSF PIRSF005622 1 368 2.9E-159 T 28-03-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 MKLM6_RS19290 d83366a71864bb2f276151137bcbac02 369 Pfam PF01924 Hydrogenase formation hypA family 12 364 1.5E-156 T 28-03-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 MKLM6_RS19290 d83366a71864bb2f276151137bcbac02 369 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 3 367 7.5E-147 T 28-03-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 MKLM6_RS17250 2cf008fdc8340bfc48d05081a5ce8563 593 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 6 144 8.0E-30 T 28-03-2018 MKLM6_RS17250 2cf008fdc8340bfc48d05081a5ce8563 593 SMART SM00928 471 516 2.0E-18 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS17250 2cf008fdc8340bfc48d05081a5ce8563 593 SUPERFAMILY SSF142019 189 393 5.49E-64 T 28-03-2018 MKLM6_RS17250 2cf008fdc8340bfc48d05081a5ce8563 593 SUPERFAMILY SSF52833 4 167 4.58E-32 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS17250 2cf008fdc8340bfc48d05081a5ce8563 593 Gene3D G3DSA:3.40.30.10 80 160 0.0012 T 28-03-2018 MKLM6_RS17250 2cf008fdc8340bfc48d05081a5ce8563 593 SUPERFAMILY SSF142984 394 465 6.15E-15 T 28-03-2018 MKLM6_RS17250 2cf008fdc8340bfc48d05081a5ce8563 593 SUPERFAMILY SSF140490 468 557 3.79E-26 T 28-03-2018 MKLM6_RS17250 2cf008fdc8340bfc48d05081a5ce8563 593 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 484 495 - T 28-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS17250 2cf008fdc8340bfc48d05081a5ce8563 593 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 473 554 1.7E-24 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS17250 2cf008fdc8340bfc48d05081a5ce8563 593 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 202 370 8.0E-40 T 28-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS12855 bde9221c90c89ca6814e862f888aa373 272 SUPERFAMILY SSF51717 3 269 8.5E-97 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MKLM6_RS12855 bde9221c90c89ca6814e862f888aa373 272 Pfam PF00809 Pterin binding enzyme 11 253 1.5E-89 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MKLM6_RS12855 bde9221c90c89ca6814e862f888aa373 272 Gene3D G3DSA:3.20.20.20 1 272 2.0E-109 T 28-03-2018 MKLM6_RS12855 bde9221c90c89ca6814e862f888aa373 272 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 10 25 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MKLM6_RS12855 bde9221c90c89ca6814e862f888aa373 272 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 9 265 5.6E-99 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 MKLM6_RS12855 bde9221c90c89ca6814e862f888aa373 272 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 44 57 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MKLM6_RS18805 da8c8bba696b0273ac724eac1048025f 262 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 137 2.9E-47 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G MKLM6_RS18805 da8c8bba696b0273ac724eac1048025f 262 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 147 244 1.3E-33 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G MKLM6_RS18805 da8c8bba696b0273ac724eac1048025f 262 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 12 32 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site MKLM6_RS18805 da8c8bba696b0273ac724eac1048025f 262 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 183 258 3.8E-27 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain MKLM6_RS18805 da8c8bba696b0273ac724eac1048025f 262 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 5 261 2.2E-116 T 28-03-2018 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 MKLM6_RS18805 da8c8bba696b0273ac724eac1048025f 262 Pfam PF00460 Flagella basal body rod protein 6 36 1.8E-15 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 MKLM6_RS18805 da8c8bba696b0273ac724eac1048025f 262 SUPERFAMILY SSF117143 93 223 4.32E-36 T 28-03-2018 MKLM6_RS21780 3b0bef145ec7f891197cf92e6d41b6ae 459 Gene3D G3DSA:1.10.4100.10 233 443 1.1E-32 T 28-03-2018 MKLM6_RS21780 3b0bef145ec7f891197cf92e6d41b6ae 459 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 456 6.7E-217 T 28-03-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 MKLM6_RS21780 3b0bef145ec7f891197cf92e6d41b6ae 459 Pfam PF03315 Serine dehydratase beta chain 4 154 3.0E-60 T 28-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 MKLM6_RS21780 3b0bef145ec7f891197cf92e6d41b6ae 459 SUPERFAMILY SSF143548 17 155 5.23E-46 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 MKLM6_RS21780 3b0bef145ec7f891197cf92e6d41b6ae 459 Gene3D G3DSA:3.30.1330.90 11 159 7.5E-58 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 MKLM6_RS21780 3b0bef145ec7f891197cf92e6d41b6ae 459 Pfam PF03313 Serine dehydratase alpha chain 187 453 4.3E-104 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit MKLM6_RS00695 efd5dc0ce56930659bae42cafc98e34b 173 Pfam PF04542 Sigma-70 region 2 20 83 9.3E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS00695 efd5dc0ce56930659bae42cafc98e34b 173 Gene3D G3DSA:1.10.10.10 82 173 6.5E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS00695 efd5dc0ce56930659bae42cafc98e34b 173 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 169 3.5E-21 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS00695 efd5dc0ce56930659bae42cafc98e34b 173 SUPERFAMILY SSF88946 15 95 1.33E-12 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS00695 efd5dc0ce56930659bae42cafc98e34b 173 Pfam PF08281 Sigma-70, region 4 114 166 4.1E-19 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS00695 efd5dc0ce56930659bae42cafc98e34b 173 SUPERFAMILY SSF88659 84 170 6.11E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS00695 efd5dc0ce56930659bae42cafc98e34b 173 Gene3D G3DSA:1.10.1740.10 9 81 4.7E-14 T 28-03-2018 MKLM6_RS19140 a19dfdb5067b2d0cda2a4047c40d5a41 364 SUPERFAMILY SSF101898 216 328 7.59E-17 T 28-03-2018 MKLM6_RS19140 a19dfdb5067b2d0cda2a4047c40d5a41 364 SUPERFAMILY SSF101898 29 186 7.59E-17 T 28-03-2018 MKLM6_RS19140 a19dfdb5067b2d0cda2a4047c40d5a41 364 Pfam PF03022 Major royal jelly protein 90 344 8.6E-17 T 28-03-2018 IPR017996 Major royal jelly protein/protein yellow MKLM6_RS19140 a19dfdb5067b2d0cda2a4047c40d5a41 364 Gene3D G3DSA:2.120.10.30 18 364 1.5E-34 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MKLM6_RS21110 cd066f8c7b5f80026df7e65e6dd8579e 151 Pfam PF04364 DNA polymerase III chi subunit, HolC 11 146 8.1E-33 T 28-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 MKLM6_RS21110 cd066f8c7b5f80026df7e65e6dd8579e 151 SUPERFAMILY SSF102400 11 150 6.41E-34 T 28-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 MKLM6_RS21110 cd066f8c7b5f80026df7e65e6dd8579e 151 Gene3D G3DSA:3.40.50.10110 7 151 4.3E-40 T 28-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 MKLM6_RS07040 1d363c1d7d114c3aa155c3e57c11a416 373 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 4 357 55.625 T 28-03-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 MKLM6_RS07040 1d363c1d7d114c3aa155c3e57c11a416 373 Gene3D G3DSA:3.90.25.10 250 373 3.4E-32 T 28-03-2018 MKLM6_RS07040 1d363c1d7d114c3aa155c3e57c11a416 373 Gene3D G3DSA:3.90.25.10 207 249 1.3E-19 T 28-03-2018 MKLM6_RS07040 1d363c1d7d114c3aa155c3e57c11a416 373 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 4 354 9.1E-177 T 28-03-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 MKLM6_RS07040 1d363c1d7d114c3aa155c3e57c11a416 373 SUPERFAMILY SSF51735 4 353 1.39E-87 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS07040 1d363c1d7d114c3aa155c3e57c11a416 373 Pfam PF16363 GDP-mannose 4,6 dehydratase 7 347 8.6E-159 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS07040 1d363c1d7d114c3aa155c3e57c11a416 373 Gene3D G3DSA:3.40.50.720 1 206 5.5E-24 T 28-03-2018 MKLM6_RS13340 fd0ea572fd39e0174ba08b12458927f0 125 Pfam PF04892 VanZ like family 40 113 3.3E-10 T 28-03-2018 IPR006976 VanZ-like MKLM6_RS11150 b7fc0ca4ffdb14b1a128f4b80f76949f 500 Gene3D G3DSA:3.30.420.150 122 302 2.1E-31 T 28-03-2018 MKLM6_RS11150 b7fc0ca4ffdb14b1a128f4b80f76949f 500 Gene3D G3DSA:3.30.420.40 1 121 1.0E-38 T 28-03-2018 MKLM6_RS11150 b7fc0ca4ffdb14b1a128f4b80f76949f 500 PIRSF PIRSF001267 1 499 1.6E-172 T 28-03-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 MKLM6_RS11150 b7fc0ca4ffdb14b1a128f4b80f76949f 500 SUPERFAMILY SSF53067 134 306 3.7E-40 T 28-03-2018 MKLM6_RS11150 b7fc0ca4ffdb14b1a128f4b80f76949f 500 SUPERFAMILY SSF53067 9 128 9.07E-36 T 28-03-2018 MKLM6_RS11150 b7fc0ca4ffdb14b1a128f4b80f76949f 500 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 9 303 3.5E-95 T 28-03-2018 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 MKLM6_RS11150 b7fc0ca4ffdb14b1a128f4b80f76949f 500 SUPERFAMILY SSF109604 310 497 5.97E-41 T 28-03-2018 MKLM6_RS11150 b7fc0ca4ffdb14b1a128f4b80f76949f 500 Pfam PF02541 Ppx/GppA phosphatase family 23 304 1.6E-68 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 Hamap MF_01417 Biosynthetic arginine decarboxylase [speA]. 11 614 39.632 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 Gene3D G3DSA:2.40.37.10 355 561 1.8E-65 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 Gene3D G3DSA:2.40.37.10 6 86 2.7E-19 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 281 294 - T 28-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 524 537 1.5E-16 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 337 356 1.5E-16 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 106 124 1.5E-16 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 243 256 1.5E-16 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 127 139 1.5E-16 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 TIGRFAM TIGR01273 speA: arginine decarboxylase 13 613 2.0E-238 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 Gene3D G3DSA:3.20.20.10 87 349 6.2E-40 T 28-03-2018 IPR029066 PLP-binding barrel MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 SUPERFAMILY SSF51419 75 349 1.6E-64 T 28-03-2018 IPR029066 PLP-binding barrel MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 PIRSF PIRSF001336 2 614 1.6E-234 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 SUPERFAMILY SSF50621 441 546 1.43E-6 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 92 347 1.2E-45 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 PRINTS PR01180 Arginine decarboxylase signature 74 89 4.0E-67 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 PRINTS PR01180 Arginine decarboxylase signature 98 112 4.0E-67 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 PRINTS PR01180 Arginine decarboxylase signature 150 165 4.0E-67 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 PRINTS PR01180 Arginine decarboxylase signature 471 496 4.0E-67 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 PRINTS PR01180 Arginine decarboxylase signature 200 222 4.0E-67 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 PRINTS PR01180 Arginine decarboxylase signature 176 197 4.0E-67 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 PRINTS PR01180 Arginine decarboxylase signature 327 344 4.0E-67 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 PRINTS PR01180 Arginine decarboxylase signature 524 545 4.0E-67 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MKLM6_RS20620 0ebf9c6f7b88b1b4eaf5dfc825607c6e 614 PRINTS PR01180 Arginine decarboxylase signature 446 467 4.0E-67 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MKLM6_RS17430 152e401ce8f15116b568508e1cef68b0 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 1.6E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS17430 152e401ce8f15116b568508e1cef68b0 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 1.6E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS17430 152e401ce8f15116b568508e1cef68b0 216 Pfam PF00072 Response regulator receiver domain 4 115 5.5E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS17430 152e401ce8f15116b568508e1cef68b0 216 Gene3D G3DSA:3.40.50.2300 1 126 1.1E-34 T 28-03-2018 MKLM6_RS17430 152e401ce8f15116b568508e1cef68b0 216 SUPERFAMILY SSF52172 1 130 1.11E-32 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS17430 152e401ce8f15116b568508e1cef68b0 216 SUPERFAMILY SSF46894 141 209 4.42E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MKLM6_RS17430 152e401ce8f15116b568508e1cef68b0 216 SMART SM00448 2 115 5.4E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS17430 152e401ce8f15116b568508e1cef68b0 216 Gene3D G3DSA:1.10.10.10 127 212 4.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS17430 152e401ce8f15116b568508e1cef68b0 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 202 2.7E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS17430 152e401ce8f15116b568508e1cef68b0 216 SMART SM00421 145 202 1.8E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS08130 1da8b6d8ddd1fd689c1d4c846bc698e2 125 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 5 124 1.3E-24 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 MKLM6_RS08130 1da8b6d8ddd1fd689c1d4c846bc698e2 125 Gene3D G3DSA:3.30.479.10 1 125 5.7E-24 T 28-03-2018 MKLM6_RS08130 1da8b6d8ddd1fd689c1d4c846bc698e2 125 SUPERFAMILY SSF55620 1 123 6.12E-24 T 28-03-2018 MKLM6_RS18025 2918908e9893c116236a509e0f6ee802 350 Pfam PF00483 Nucleotidyl transferase 125 344 3.4E-37 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MKLM6_RS18025 2918908e9893c116236a509e0f6ee802 350 SMART SM00116 70 118 88.0 T 28-03-2018 IPR000644 CBS domain MKLM6_RS18025 2918908e9893c116236a509e0f6ee802 350 SMART SM00116 6 54 0.0064 T 28-03-2018 IPR000644 CBS domain MKLM6_RS18025 2918908e9893c116236a509e0f6ee802 350 Gene3D G3DSA:3.10.580.10 1 116 4.6E-17 T 28-03-2018 MKLM6_RS18025 2918908e9893c116236a509e0f6ee802 350 SUPERFAMILY SSF53448 48 349 3.29E-65 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS18025 2918908e9893c116236a509e0f6ee802 350 Pfam PF00571 CBS domain 9 53 2.6E-7 T 28-03-2018 IPR000644 CBS domain MKLM6_RS18025 2918908e9893c116236a509e0f6ee802 350 Pfam PF00571 CBS domain 63 105 0.0053 T 28-03-2018 IPR000644 CBS domain MKLM6_RS18025 2918908e9893c116236a509e0f6ee802 350 Gene3D G3DSA:3.90.550.10 121 349 7.6E-53 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS21010 c804fd563d6ed2b7d9497f0b2b9bf896 811 Pfam PF00593 TonB dependent receptor 326 809 3.9E-58 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS21010 c804fd563d6ed2b7d9497f0b2b9bf896 811 Gene3D G3DSA:2.170.130.10 112 265 9.8E-24 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS21010 c804fd563d6ed2b7d9497f0b2b9bf896 811 Gene3D G3DSA:2.40.170.20 267 811 3.2E-90 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS21010 c804fd563d6ed2b7d9497f0b2b9bf896 811 SMART SM00965 56 107 2.9E-10 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MKLM6_RS21010 c804fd563d6ed2b7d9497f0b2b9bf896 811 SUPERFAMILY SSF56935 116 811 7.85E-137 T 28-03-2018 MKLM6_RS21010 c804fd563d6ed2b7d9497f0b2b9bf896 811 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 159 811 7.1E-111 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 MKLM6_RS21010 c804fd563d6ed2b7d9497f0b2b9bf896 811 Pfam PF07715 TonB-dependent Receptor Plug Domain 158 252 2.4E-15 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS18200 930100a5c2ba9188153f5c93eb91b8ea 677 Pfam PF00067 Cytochrome P450 562 651 4.1E-9 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MKLM6_RS18200 930100a5c2ba9188153f5c93eb91b8ea 677 Pfam PF00067 Cytochrome P450 450 550 2.8E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MKLM6_RS18200 930100a5c2ba9188153f5c93eb91b8ea 677 SUPERFAMILY SSF48264 299 657 2.62E-49 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MKLM6_RS18200 930100a5c2ba9188153f5c93eb91b8ea 677 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 625 634 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MKLM6_RS18200 930100a5c2ba9188153f5c93eb91b8ea 677 SUPERFAMILY SSF47616 145 231 8.67E-7 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like MKLM6_RS18200 930100a5c2ba9188153f5c93eb91b8ea 677 Gene3D G3DSA:1.20.1050.10 109 261 1.8E-7 T 28-03-2018 MKLM6_RS18200 930100a5c2ba9188153f5c93eb91b8ea 677 Gene3D G3DSA:3.40.30.10 4 108 1.4E-5 T 28-03-2018 MKLM6_RS18200 930100a5c2ba9188153f5c93eb91b8ea 677 SUPERFAMILY SSF52833 18 106 1.79E-5 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS18200 930100a5c2ba9188153f5c93eb91b8ea 677 Gene3D G3DSA:1.10.630.10 279 658 6.3E-42 T 28-03-2018 MKLM6_RS18200 930100a5c2ba9188153f5c93eb91b8ea 677 PRINTS PR00359 B-class P450 signature 632 643 9.0E-10 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MKLM6_RS18200 930100a5c2ba9188153f5c93eb91b8ea 677 PRINTS PR00359 B-class P450 signature 574 601 9.0E-10 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MKLM6_RS18200 930100a5c2ba9188153f5c93eb91b8ea 677 PRINTS PR00359 B-class P450 signature 405 421 9.0E-10 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MKLM6_RS18200 930100a5c2ba9188153f5c93eb91b8ea 677 PRINTS PR00359 B-class P450 signature 623 632 9.0E-10 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MKLM6_RS18200 930100a5c2ba9188153f5c93eb91b8ea 677 PRINTS PR00359 B-class P450 signature 422 437 9.0E-10 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MKLM6_RS21525 9d786f0141ada5f67b29398a20369730 1020 SUPERFAMILY SSF82693 267 323 6.54E-18 T 28-03-2018 MKLM6_RS21525 9d786f0141ada5f67b29398a20369730 1020 SUPERFAMILY SSF82693 138 181 6.54E-18 T 28-03-2018 MKLM6_RS21525 9d786f0141ada5f67b29398a20369730 1020 Gene3D G3DSA:3.30.70.1430 41 141 5.8E-19 T 28-03-2018 MKLM6_RS21525 9d786f0141ada5f67b29398a20369730 1020 Gene3D G3DSA:1.20.1640.10 281 503 3.8E-41 T 28-03-2018 MKLM6_RS21525 9d786f0141ada5f67b29398a20369730 1020 Pfam PF00873 AcrB/AcrD/AcrF family 5 1012 5.1E-288 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS21525 9d786f0141ada5f67b29398a20369730 1020 SUPERFAMILY SSF82693 41 126 4.19E-19 T 28-03-2018 MKLM6_RS21525 9d786f0141ada5f67b29398a20369730 1020 Gene3D G3DSA:1.20.1640.10 809 1015 2.7E-39 T 28-03-2018 MKLM6_RS21525 9d786f0141ada5f67b29398a20369730 1020 SUPERFAMILY SSF82714 183 264 1.26E-12 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS21525 9d786f0141ada5f67b29398a20369730 1020 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 2.8E-37 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS21525 9d786f0141ada5f67b29398a20369730 1020 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 2.8E-37 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS21525 9d786f0141ada5f67b29398a20369730 1020 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 2.8E-37 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS21525 9d786f0141ada5f67b29398a20369730 1020 PRINTS PR00702 Acriflavin resistance protein family signature 540 557 2.8E-37 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS21525 9d786f0141ada5f67b29398a20369730 1020 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 2.8E-37 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS21525 9d786f0141ada5f67b29398a20369730 1020 PRINTS PR00702 Acriflavin resistance protein family signature 611 625 2.8E-37 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS21525 9d786f0141ada5f67b29398a20369730 1020 PRINTS PR00702 Acriflavin resistance protein family signature 468 491 2.8E-37 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS21525 9d786f0141ada5f67b29398a20369730 1020 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 2.8E-37 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS21525 9d786f0141ada5f67b29398a20369730 1020 Gene3D G3DSA:3.30.2090.10 712 794 1.6E-10 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS21525 9d786f0141ada5f67b29398a20369730 1020 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 3 1013 0.0 T 28-03-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 MKLM6_RS21525 9d786f0141ada5f67b29398a20369730 1020 SUPERFAMILY SSF82714 713 790 2.49E-9 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS21525 9d786f0141ada5f67b29398a20369730 1020 SUPERFAMILY SSF82866 290 495 2.75E-41 T 28-03-2018 MKLM6_RS21525 9d786f0141ada5f67b29398a20369730 1020 SUPERFAMILY SSF82866 791 1014 1.44E-53 T 28-03-2018 MKLM6_RS21525 9d786f0141ada5f67b29398a20369730 1020 Gene3D G3DSA:3.30.2090.10 181 267 1.1E-13 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS21525 9d786f0141ada5f67b29398a20369730 1020 Gene3D G3DSA:3.30.70.1430 555 659 2.5E-10 T 28-03-2018 MKLM6_RS02465 4fdc1e288ca560e0b933ef731a6b7854 1091 SMART SM00091 542 608 3.0E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS02465 4fdc1e288ca560e0b933ef731a6b7854 1091 Gene3D G3DSA:3.30.450.20 517 664 9.0E-27 T 28-03-2018 MKLM6_RS02465 4fdc1e288ca560e0b933ef731a6b7854 1091 Pfam PF00990 Diguanylate cyclase, GGDEF domain 667 828 4.2E-51 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS02465 4fdc1e288ca560e0b933ef731a6b7854 1091 Pfam PF03924 CHASE domain 258 430 1.5E-30 T 28-03-2018 IPR006189 CHASE domain MKLM6_RS02465 4fdc1e288ca560e0b933ef731a6b7854 1091 SMART SM00052 843 1088 3.0E-115 T 28-03-2018 IPR001633 EAL domain MKLM6_RS02465 4fdc1e288ca560e0b933ef731a6b7854 1091 SUPERFAMILY SSF55073 672 835 3.92E-50 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS02465 4fdc1e288ca560e0b933ef731a6b7854 1091 Pfam PF13426 PAS domain 553 655 1.2E-14 T 28-03-2018 IPR000014 PAS domain MKLM6_RS02465 4fdc1e288ca560e0b933ef731a6b7854 1091 Gene3D G3DSA:3.20.20.450 840 1091 9.5E-102 T 28-03-2018 IPR001633 EAL domain MKLM6_RS02465 4fdc1e288ca560e0b933ef731a6b7854 1091 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 539 662 1.2E-19 T 28-03-2018 IPR000014 PAS domain MKLM6_RS02465 4fdc1e288ca560e0b933ef731a6b7854 1091 SMART SM00086 614 656 1.0E-6 T 28-03-2018 IPR001610 PAC motif MKLM6_RS02465 4fdc1e288ca560e0b933ef731a6b7854 1091 Gene3D G3DSA:3.30.70.270 665 839 1.8E-63 T 28-03-2018 MKLM6_RS02465 4fdc1e288ca560e0b933ef731a6b7854 1091 SMART SM01079 256 436 4.6E-29 T 28-03-2018 IPR006189 CHASE domain MKLM6_RS02465 4fdc1e288ca560e0b933ef731a6b7854 1091 SUPERFAMILY SSF55785 553 665 7.09E-26 T 28-03-2018 IPR000014 PAS domain MKLM6_RS02465 4fdc1e288ca560e0b933ef731a6b7854 1091 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 665 831 7.9E-45 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS02465 4fdc1e288ca560e0b933ef731a6b7854 1091 SMART SM00267 656 833 4.4E-68 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS02465 4fdc1e288ca560e0b933ef731a6b7854 1091 Pfam PF00563 EAL domain 849 1083 9.4E-75 T 28-03-2018 IPR001633 EAL domain MKLM6_RS02465 4fdc1e288ca560e0b933ef731a6b7854 1091 SUPERFAMILY SSF141868 848 1090 1.96E-89 T 28-03-2018 IPR001633 EAL domain MKLM6_RS02465 4fdc1e288ca560e0b933ef731a6b7854 1091 Pfam PF05231 MASE1 13 211 1.9E-22 T 28-03-2018 IPR007895 MASE1 MKLM6_RS09105 8fff1bc893012197a358f5dd750e328f 221 Pfam PF11172 Protein of unknown function (DUF2959) 13 206 3.4E-75 T 28-03-2018 IPR021342 Protein of unknown function DUF2959 MKLM6_RS09105 8fff1bc893012197a358f5dd750e328f 221 Gene3D G3DSA:1.20.120.330 14 165 2.7E-5 T 28-03-2018 MKLM6_RS18675 cbbda32095901a93a5ad74a6b8f43744 787 SUPERFAMILY SSF56935 126 785 3.4E-94 T 28-03-2018 MKLM6_RS18675 cbbda32095901a93a5ad74a6b8f43744 787 Gene3D G3DSA:2.170.130.10 121 267 7.5E-24 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS18675 cbbda32095901a93a5ad74a6b8f43744 787 SMART SM00965 62 113 3.0E-9 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MKLM6_RS18675 cbbda32095901a93a5ad74a6b8f43744 787 Pfam PF07715 TonB-dependent Receptor Plug Domain 147 255 4.7E-20 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS18675 cbbda32095901a93a5ad74a6b8f43744 787 Gene3D G3DSA:2.40.170.20 269 785 9.8E-59 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS18675 cbbda32095901a93a5ad74a6b8f43744 787 Pfam PF07660 Secretin and TonB N terminus short domain 64 112 1.1E-7 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MKLM6_RS18675 cbbda32095901a93a5ad74a6b8f43744 787 Pfam PF00593 TonB dependent receptor 364 784 1.0E-31 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS09970 4941d51a7723af9a745e658f997cb40d 545 Pfam PF13432 Tetratricopeptide repeat 186 244 1.4E-4 T 28-03-2018 MKLM6_RS09970 4941d51a7723af9a745e658f997cb40d 545 Pfam PF13432 Tetratricopeptide repeat 127 181 1.3E-7 T 28-03-2018 MKLM6_RS09970 4941d51a7723af9a745e658f997cb40d 545 Pfam PF13432 Tetratricopeptide repeat 48 82 0.019 T 28-03-2018 MKLM6_RS09970 4941d51a7723af9a745e658f997cb40d 545 Pfam PF02810 SEC-C motif 11 28 2.5E-9 T 28-03-2018 IPR004027 SEC-C motif MKLM6_RS09970 4941d51a7723af9a745e658f997cb40d 545 Pfam PF13469 Sulfotransferase family 293 486 1.2E-26 T 28-03-2018 MKLM6_RS09970 4941d51a7723af9a745e658f997cb40d 545 SUPERFAMILY SSF103642 10 29 7.19E-7 T 28-03-2018 MKLM6_RS09970 4941d51a7723af9a745e658f997cb40d 545 SUPERFAMILY SSF48452 119 252 5.84E-20 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS09970 4941d51a7723af9a745e658f997cb40d 545 Gene3D G3DSA:1.25.40.10 112 171 2.9E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS09970 4941d51a7723af9a745e658f997cb40d 545 SUPERFAMILY SSF52540 288 544 7.59E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS09970 4941d51a7723af9a745e658f997cb40d 545 SMART SM00028 147 180 4.6E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS09970 4941d51a7723af9a745e658f997cb40d 545 SMART SM00028 39 73 490.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS09970 4941d51a7723af9a745e658f997cb40d 545 SMART SM00028 218 251 12.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS09970 4941d51a7723af9a745e658f997cb40d 545 SMART SM00028 181 214 120.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS09970 4941d51a7723af9a745e658f997cb40d 545 Gene3D G3DSA:1.25.40.10 45 111 8.5E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS09970 4941d51a7723af9a745e658f997cb40d 545 Gene3D G3DSA:1.25.40.10 192 261 1.8E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS09970 4941d51a7723af9a745e658f997cb40d 545 Gene3D G3DSA:1.25.40.10 172 191 2.8E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS09970 4941d51a7723af9a745e658f997cb40d 545 Gene3D G3DSA:3.10.450.50 2 30 1.0E-8 T 28-03-2018 MKLM6_RS09970 4941d51a7723af9a745e658f997cb40d 545 Gene3D G3DSA:3.40.50.300 290 528 2.2E-32 T 28-03-2018 MKLM6_RS21030 5a33846aa27d91c514d99df8c7b3e3d7 402 Pfam PF03929 PepSY-associated TM region 10 393 1.4E-59 T 28-03-2018 IPR005625 PepSY-associated TM protein MKLM6_RS16730 00c3d942bd3ea751e0fb0e59fb91c9a9 759 SUPERFAMILY SSF46626 397 451 4.37E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS16730 00c3d942bd3ea751e0fb0e59fb91c9a9 759 SUPERFAMILY SSF46626 612 702 4.37E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS16730 00c3d942bd3ea751e0fb0e59fb91c9a9 759 Gene3D G3DSA:1.10.760.10 48 371 7.0E-28 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS16730 00c3d942bd3ea751e0fb0e59fb91c9a9 759 Gene3D G3DSA:1.10.760.10 372 706 5.3E-28 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS16730 00c3d942bd3ea751e0fb0e59fb91c9a9 759 SUPERFAMILY SSF46626 249 285 5.03E-13 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS16730 00c3d942bd3ea751e0fb0e59fb91c9a9 759 SUPERFAMILY SSF46626 180 211 5.03E-13 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS16730 00c3d942bd3ea751e0fb0e59fb91c9a9 759 SUPERFAMILY SSF46626 52 78 5.03E-13 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS16730 00c3d942bd3ea751e0fb0e59fb91c9a9 759 Pfam PF03150 Di-haem cytochrome c peroxidase 53 377 1.8E-22 T 28-03-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 MKLM6_RS20775 2b4349f2308ec6afc6aa7477bb78285d 275 SUPERFAMILY SSF51690 107 270 5.49E-58 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MKLM6_RS20775 2b4349f2308ec6afc6aa7477bb78285d 275 Gene3D G3DSA:3.90.1170.20 2 131 9.8E-42 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 MKLM6_RS20775 2b4349f2308ec6afc6aa7477bb78285d 275 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 107 269 5.2E-57 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MKLM6_RS20775 2b4349f2308ec6afc6aa7477bb78285d 275 SUPERFAMILY SSF54675 6 104 9.81E-31 T 28-03-2018 MKLM6_RS20775 2b4349f2308ec6afc6aa7477bb78285d 275 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 8 270 3.7E-92 T 28-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 MKLM6_RS20775 2b4349f2308ec6afc6aa7477bb78285d 275 PIRSF PIRSF006250 2 273 5.1E-93 T 28-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 MKLM6_RS20775 2b4349f2308ec6afc6aa7477bb78285d 275 Gene3D G3DSA:3.20.20.70 132 260 8.0E-40 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS20775 2b4349f2308ec6afc6aa7477bb78285d 275 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 16 104 2.6E-26 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 MKLM6_RS00420 5423c542e65ac1f2e55461c5fddfc469 79 Gene3D G3DSA:2.30.30.400 5 79 1.0E-24 T 28-03-2018 MKLM6_RS00420 5423c542e65ac1f2e55461c5fddfc469 79 Pfam PF07073 Modulator of Rho-dependent transcription termination (ROF) 4 79 1.9E-26 T 28-03-2018 IPR009778 Modulator of Rho-dependent transcription termination MKLM6_RS00420 5423c542e65ac1f2e55461c5fddfc469 79 SUPERFAMILY SSF101744 3 77 5.07E-19 T 28-03-2018 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 MKLM6_RS22560 301d7e4b61d9ee66a8e82ea9d5351491 259 Pfam PF10411 Disulfide bond isomerase protein N-terminus 42 88 9.2E-6 T 28-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal MKLM6_RS22560 301d7e4b61d9ee66a8e82ea9d5351491 259 Gene3D G3DSA:3.40.30.10 118 259 1.9E-9 T 28-03-2018 MKLM6_RS22560 301d7e4b61d9ee66a8e82ea9d5351491 259 Pfam PF13098 Thioredoxin-like domain 122 239 4.0E-7 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS22560 301d7e4b61d9ee66a8e82ea9d5351491 259 SUPERFAMILY SSF52833 106 249 8.01E-17 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS22560 301d7e4b61d9ee66a8e82ea9d5351491 259 Gene3D G3DSA:3.10.450.70 37 89 2.3E-6 T 28-03-2018 MKLM6_RS21165 80f77f30c3351da06c3617eaf31eaa29 291 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 76 279 9.8E-75 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MKLM6_RS21165 80f77f30c3351da06c3617eaf31eaa29 291 Gene3D G3DSA:3.90.850.10 34 287 2.1E-86 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MKLM6_RS21165 80f77f30c3351da06c3617eaf31eaa29 291 SUPERFAMILY SSF56529 62 278 8.5E-85 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MKLM6_RS01210 4bdd1c5b1e64efc98c84f94bae0a463a 824 SUPERFAMILY SSF56935 321 824 1.83E-105 T 28-03-2018 MKLM6_RS01210 4bdd1c5b1e64efc98c84f94bae0a463a 824 SUPERFAMILY SSF56935 91 282 1.83E-105 T 28-03-2018 MKLM6_RS01210 4bdd1c5b1e64efc98c84f94bae0a463a 824 Pfam PF07715 TonB-dependent Receptor Plug Domain 114 223 5.6E-22 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS01210 4bdd1c5b1e64efc98c84f94bae0a463a 824 Gene3D G3DSA:2.170.130.10 89 224 6.1E-27 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS01210 4bdd1c5b1e64efc98c84f94bae0a463a 824 Pfam PF00593 TonB dependent receptor 359 823 1.5E-52 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS01210 4bdd1c5b1e64efc98c84f94bae0a463a 824 Gene3D G3DSA:2.40.170.20 225 824 1.7E-75 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS06905 ccb47391c6a8a4571ffbd4e64d2bb7c6 1279 SUPERFAMILY SSF55073 845 1000 1.65E-23 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS06905 ccb47391c6a8a4571ffbd4e64d2bb7c6 1279 Pfam PF07793 Protein of unknown function (DUF1631) 170 830 2.5E-87 T 28-03-2018 IPR012434 Protein of unknown function DUF1631 MKLM6_RS06905 ccb47391c6a8a4571ffbd4e64d2bb7c6 1279 SUPERFAMILY SSF141868 1042 1263 4.97E-63 T 28-03-2018 IPR001633 EAL domain MKLM6_RS06905 ccb47391c6a8a4571ffbd4e64d2bb7c6 1279 Pfam PF00563 EAL domain 1044 1253 7.4E-57 T 28-03-2018 IPR001633 EAL domain MKLM6_RS06905 ccb47391c6a8a4571ffbd4e64d2bb7c6 1279 SUPERFAMILY SSF141371 9 109 1.26E-8 T 28-03-2018 MKLM6_RS06905 ccb47391c6a8a4571ffbd4e64d2bb7c6 1279 Gene3D G3DSA:2.40.10.220 4 118 9.2E-10 T 28-03-2018 MKLM6_RS06905 ccb47391c6a8a4571ffbd4e64d2bb7c6 1279 SMART SM00267 828 998 3.0E-17 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS06905 ccb47391c6a8a4571ffbd4e64d2bb7c6 1279 Pfam PF00990 Diguanylate cyclase, GGDEF domain 839 993 1.2E-20 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS06905 ccb47391c6a8a4571ffbd4e64d2bb7c6 1279 SMART SM00052 1010 1258 1.0E-54 T 28-03-2018 IPR001633 EAL domain MKLM6_RS06905 ccb47391c6a8a4571ffbd4e64d2bb7c6 1279 Gene3D G3DSA:3.30.70.270 833 1012 7.4E-30 T 28-03-2018 MKLM6_RS06905 ccb47391c6a8a4571ffbd4e64d2bb7c6 1279 Gene3D G3DSA:3.20.20.450 1013 1266 2.0E-67 T 28-03-2018 IPR001633 EAL domain MKLM6_RS06905 ccb47391c6a8a4571ffbd4e64d2bb7c6 1279 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 838 997 1.2E-18 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS08030 6f7217dabec5623617d58b8cc8e164f4 205 Gene3D G3DSA:3.40.30.10 20 205 4.3E-26 T 28-03-2018 MKLM6_RS08030 6f7217dabec5623617d58b8cc8e164f4 205 Pfam PF00578 AhpC/TSA family 28 154 9.1E-14 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MKLM6_RS08030 6f7217dabec5623617d58b8cc8e164f4 205 SUPERFAMILY SSF52833 26 203 7.59E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS20995 2125c69572a148d531a8ddeb44949822 321 Pfam PF04773 FecR protein 112 206 3.4E-19 T 28-03-2018 IPR006860 FecR protein MKLM6_RS20995 2125c69572a148d531a8ddeb44949822 321 PIRSF PIRSF018266 4 321 1.4E-89 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component MKLM6_RS20995 2125c69572a148d531a8ddeb44949822 321 Pfam PF16220 Domain of unknown function (DUF4880) 16 55 5.7E-11 T 28-03-2018 IPR032623 FecR, N-terminal MKLM6_RS14505 73fa2bec8b2a57949bceab8b30a7ecee 238 Gene3D G3DSA:2.40.160.60 50 233 7.4E-5 T 28-03-2018 MKLM6_RS14505 73fa2bec8b2a57949bceab8b30a7ecee 238 Pfam PF10677 Protein of unknown function (DUF2490) 35 223 7.4E-42 T 28-03-2018 IPR019619 Protein of unknown function DUF2490 MKLM6_RS21530 ebc4262aac70da0da8fcb948cf324815 354 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 41 345 5.7E-34 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MKLM6_RS21530 ebc4262aac70da0da8fcb948cf324815 354 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 42 268 2.8E-38 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MKLM6_RS21530 ebc4262aac70da0da8fcb948cf324815 354 Gene3D G3DSA:2.40.50.100 43 208 3.1E-14 T 28-03-2018 MKLM6_RS21530 ebc4262aac70da0da8fcb948cf324815 354 SUPERFAMILY SSF111369 50 275 4.84E-11 T 28-03-2018 MKLM6_RS13190 e6270843441e61c5b9e33a04f6ef7eec 198 Gene3D G3DSA:3.30.1330.60 45 198 3.7E-24 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS13190 e6270843441e61c5b9e33a04f6ef7eec 198 SUPERFAMILY SSF103088 95 197 3.53E-22 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS13190 e6270843441e61c5b9e33a04f6ef7eec 198 Pfam PF00691 OmpA family 96 191 2.0E-13 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS13190 e6270843441e61c5b9e33a04f6ef7eec 198 PRINTS PR01021 OMPA domain signature 127 142 8.4E-5 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MKLM6_RS13190 e6270843441e61c5b9e33a04f6ef7eec 198 PRINTS PR01021 OMPA domain signature 97 119 8.4E-5 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MKLM6_RS13190 e6270843441e61c5b9e33a04f6ef7eec 198 PRINTS PR01021 OMPA domain signature 142 158 8.4E-5 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MKLM6_RS12685 1e5e6ccf1eac26788eeb47f15c596b48 161 Gene3D G3DSA:2.40.280.10 17 136 6.5E-47 T 28-03-2018 IPR023620 Small protein B MKLM6_RS12685 1e5e6ccf1eac26788eeb47f15c596b48 161 ProSitePatterns PS01317 SsrA-binding protein. 35 47 - T 28-03-2018 IPR020081 SsrA-binding protein, conserved site MKLM6_RS12685 1e5e6ccf1eac26788eeb47f15c596b48 161 SUPERFAMILY SSF74982 11 141 5.23E-50 T 28-03-2018 IPR023620 Small protein B MKLM6_RS12685 1e5e6ccf1eac26788eeb47f15c596b48 161 Pfam PF01668 SmpB protein 17 160 3.2E-58 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 MKLM6_RS12685 1e5e6ccf1eac26788eeb47f15c596b48 161 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 17 121 2.0E-33 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 MKLM6_RS12685 1e5e6ccf1eac26788eeb47f15c596b48 161 TIGRFAM TIGR00086 smpB: SsrA-binding protein 17 159 1.0E-52 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 MKLM6_RS12685 1e5e6ccf1eac26788eeb47f15c596b48 161 Hamap MF_00023 SsrA-binding protein [smpB]. 1 161 70.197 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 MKLM6_RS21435 f73913ebebdadedc8990ce1486e78b7a 432 Gene3D G3DSA:3.50.50.60 140 180 0.068 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS21435 f73913ebebdadedc8990ce1486e78b7a 432 SUPERFAMILY SSF51905 2 347 1.72E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS21435 f73913ebebdadedc8990ce1486e78b7a 432 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 337 1.2E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS21435 f73913ebebdadedc8990ce1486e78b7a 432 Gene3D G3DSA:3.40.50.720 181 392 3.5E-34 T 28-03-2018 MKLM6_RS21435 f73913ebebdadedc8990ce1486e78b7a 432 Gene3D G3DSA:3.50.50.60 1 139 7.5E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS21435 f73913ebebdadedc8990ce1486e78b7a 432 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 7.7E-7 T 28-03-2018 MKLM6_RS21435 f73913ebebdadedc8990ce1486e78b7a 432 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 7.7E-7 T 28-03-2018 MKLM6_RS21435 f73913ebebdadedc8990ce1486e78b7a 432 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 173 198 7.7E-7 T 28-03-2018 MKLM6_RS21435 f73913ebebdadedc8990ce1486e78b7a 432 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 113 131 5.2E-18 T 28-03-2018 MKLM6_RS21435 f73913ebebdadedc8990ce1486e78b7a 432 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 5.2E-18 T 28-03-2018 MKLM6_RS21435 f73913ebebdadedc8990ce1486e78b7a 432 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 5.2E-18 T 28-03-2018 MKLM6_RS21435 f73913ebebdadedc8990ce1486e78b7a 432 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 5.2E-18 T 28-03-2018 MKLM6_RS05905 a4f2b6307ce6677cf78fe3de9a433970 133 Pfam PF01850 PIN domain 3 124 7.9E-15 T 28-03-2018 IPR002716 PIN domain MKLM6_RS05905 a4f2b6307ce6677cf78fe3de9a433970 133 Gene3D G3DSA:3.40.50.1010 1 133 7.0E-26 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS05905 a4f2b6307ce6677cf78fe3de9a433970 133 SUPERFAMILY SSF88723 1 131 1.46E-31 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS18505 07b16f50be5e824ce3c8ef616f5cdcaf 126 Hamap MF_00422 Protein translocase subunit SecE [secE]. 61 119 11.875 T 28-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MKLM6_RS18505 07b16f50be5e824ce3c8ef616f5cdcaf 126 PRINTS PR01650 Bacterial translocase SecE signature 42 63 1.7E-16 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 MKLM6_RS18505 07b16f50be5e824ce3c8ef616f5cdcaf 126 PRINTS PR01650 Bacterial translocase SecE signature 107 123 1.7E-16 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 MKLM6_RS18505 07b16f50be5e824ce3c8ef616f5cdcaf 126 PRINTS PR01650 Bacterial translocase SecE signature 87 107 1.7E-16 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 MKLM6_RS18505 07b16f50be5e824ce3c8ef616f5cdcaf 126 PRINTS PR01650 Bacterial translocase SecE signature 63 83 1.7E-16 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 MKLM6_RS18505 07b16f50be5e824ce3c8ef616f5cdcaf 126 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 68 120 1.7E-17 T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MKLM6_RS18505 07b16f50be5e824ce3c8ef616f5cdcaf 126 Gene3D G3DSA:1.20.5.1030 66 117 4.2E-16 T 28-03-2018 MKLM6_RS18505 07b16f50be5e824ce3c8ef616f5cdcaf 126 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 69 121 1.5E-15 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 MKLM6_RS17450 db2c8d6daa6d981b70cf9b766a743b5f 224 SUPERFAMILY SSF51569 3 215 2.62E-58 T 28-03-2018 MKLM6_RS17450 db2c8d6daa6d981b70cf9b766a743b5f 224 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 4 210 8.9E-38 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 MKLM6_RS17450 db2c8d6daa6d981b70cf9b766a743b5f 224 Gene3D G3DSA:3.20.20.70 2 221 1.3E-52 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS17450 db2c8d6daa6d981b70cf9b766a743b5f 224 ProSitePatterns PS01054 Transaldolase signature 1. 25 33 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 MKLM6_RS10835 89a99796dc4ef10e276e2335687beadd 242 SUPERFAMILY SSF53474 4 240 5.26E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS10835 89a99796dc4ef10e276e2335687beadd 242 Gene3D G3DSA:3.40.50.1820 2 242 4.6E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS10835 89a99796dc4ef10e276e2335687beadd 242 Pfam PF00756 Putative esterase 65 233 4.3E-7 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 MKLM6_RS13735 4e0b3f64b20b7bbb11b25f8a2a9efd18 448 TIGRFAM TIGR03496 FliI_clade1: flagellar protein export ATPase FliI 32 445 3.5E-195 T 28-03-2018 IPR020005 Flagellar export ATPase FliI, clade 1 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MKLM6_RS13735 4e0b3f64b20b7bbb11b25f8a2a9efd18 448 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 155 366 1.0E-72 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MKLM6_RS13735 4e0b3f64b20b7bbb11b25f8a2a9efd18 448 SMART SM00382 167 350 3.1E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS13735 4e0b3f64b20b7bbb11b25f8a2a9efd18 448 Gene3D G3DSA:3.40.50.300 50 366 1.5E-82 T 28-03-2018 MKLM6_RS13735 4e0b3f64b20b7bbb11b25f8a2a9efd18 448 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 18 446 6.4E-176 T 28-03-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MKLM6_RS13735 4e0b3f64b20b7bbb11b25f8a2a9efd18 448 SUPERFAMILY SSF52540 104 372 1.0E-94 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS13735 4e0b3f64b20b7bbb11b25f8a2a9efd18 448 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 357 366 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MKLM6_RS10695 9b08c04975acdf85a15e84572cb1146d 366 Pfam PF00583 Acetyltransferase (GNAT) family 26 125 6.2E-19 T 28-03-2018 IPR000182 GNAT domain GO:0008080 MKLM6_RS10695 9b08c04975acdf85a15e84572cb1146d 366 Gene3D G3DSA:3.40.630.30 75 143 1.0E-19 T 28-03-2018 MKLM6_RS10695 9b08c04975acdf85a15e84572cb1146d 366 Gene3D G3DSA:3.40.630.30 1 74 2.6E-14 T 28-03-2018 MKLM6_RS10695 9b08c04975acdf85a15e84572cb1146d 366 Gene3D G3DSA:3.90.70.10 165 350 2.2E-18 T 28-03-2018 MKLM6_RS10695 9b08c04975acdf85a15e84572cb1146d 366 Pfam PF11814 Peptidase_C39 like family 160 364 6.5E-89 T 28-03-2018 IPR021770 Protein of unknown function DUF3335 MKLM6_RS10695 9b08c04975acdf85a15e84572cb1146d 366 SUPERFAMILY SSF55729 2 148 1.46E-32 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS20810 3b1b5c290069192f8601d39579efce78 168 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 4 162 24.174 T 28-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 MKLM6_RS20810 3b1b5c290069192f8601d39579efce78 168 Pfam PF03975 CheD chemotactic sensory transduction 52 157 1.9E-25 T 28-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 MKLM6_RS20810 3b1b5c290069192f8601d39579efce78 168 SUPERFAMILY SSF64438 9 163 4.12E-42 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic MKLM6_RS08775 cf7260785802b88fa835efbbc5bb48d9 131 Gene3D G3DSA:3.30.1330.40 1 130 1.5E-47 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MKLM6_RS08775 cf7260785802b88fa835efbbc5bb48d9 131 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 102 120 - T 28-03-2018 IPR019897 RidA, conserved site MKLM6_RS08775 cf7260785802b88fa835efbbc5bb48d9 131 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 125 6.5E-51 T 28-03-2018 IPR006056 RidA family MKLM6_RS08775 cf7260785802b88fa835efbbc5bb48d9 131 SUPERFAMILY SSF55298 1 128 7.23E-46 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MKLM6_RS08775 cf7260785802b88fa835efbbc5bb48d9 131 Pfam PF01042 Endoribonuclease L-PSP 11 125 1.1E-41 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family MKLM6_RS15525 189d271ffd1a1b80bb3133a333c76fcc 320 SMART SM00729 84 293 6.9E-10 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MKLM6_RS15525 189d271ffd1a1b80bb3133a333c76fcc 320 SUPERFAMILY SSF102114 52 314 8.63E-64 T 28-03-2018 MKLM6_RS15525 189d271ffd1a1b80bb3133a333c76fcc 320 Hamap MF_00206 Lipoyl synthase [lipA]. 1 320 150.925 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MKLM6_RS15525 189d271ffd1a1b80bb3133a333c76fcc 320 TIGRFAM TIGR00510 lipA: lipoyl synthase 28 317 1.8E-133 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MKLM6_RS15525 189d271ffd1a1b80bb3133a333c76fcc 320 Gene3D G3DSA:3.20.20.70 42 317 1.0E-25 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS15525 189d271ffd1a1b80bb3133a333c76fcc 320 PIRSF PIRSF005963 2 318 4.0E-133 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MKLM6_RS15525 189d271ffd1a1b80bb3133a333c76fcc 320 Pfam PF04055 Radical SAM superfamily 91 251 5.7E-15 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS15525 189d271ffd1a1b80bb3133a333c76fcc 320 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 29 73 1.5E-10 T 28-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MKLM6_RS20845 58c783552a0c24cafd18e63072e1ac5c 334 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 135 270 2.4E-24 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS20845 58c783552a0c24cafd18e63072e1ac5c 334 SMART SM00283 67 302 2.3E-5 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS20845 58c783552a0c24cafd18e63072e1ac5c 334 SUPERFAMILY SSF58104 103 292 4.19E-35 T 28-03-2018 MKLM6_RS20845 58c783552a0c24cafd18e63072e1ac5c 334 Gene3D G3DSA:1.10.287.950 64 280 5.1E-32 T 28-03-2018 MKLM6_RS20845 58c783552a0c24cafd18e63072e1ac5c 334 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 185 214 2.7E-15 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MKLM6_RS20845 58c783552a0c24cafd18e63072e1ac5c 334 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 156 183 2.7E-15 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MKLM6_RS05570 f3247913087d081384b5a3e004e60ff7 128 Gene3D G3DSA:1.10.260.40 52 128 5.7E-9 T 28-03-2018 MKLM6_RS05570 f3247913087d081384b5a3e004e60ff7 128 SUPERFAMILY SSF47413 56 116 3.56E-21 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MKLM6_RS00955 7014d71a0ac16de128dd4284e1176f0e 257 SUPERFAMILY SSF160950 3 255 3.27E-76 T 28-03-2018 IPR009777 Cell division protein ZapD MKLM6_RS00955 7014d71a0ac16de128dd4284e1176f0e 257 Pfam PF07072 Cell division protein 19 230 1.1E-74 T 28-03-2018 IPR009777 Cell division protein ZapD MKLM6_RS00955 7014d71a0ac16de128dd4284e1176f0e 257 Hamap MF_01092 Cell division protein ZapD [zapD]. 4 255 31.509 T 28-03-2018 IPR009777 Cell division protein ZapD MKLM6_RS00955 7014d71a0ac16de128dd4284e1176f0e 257 Gene3D G3DSA:1.10.3900.10 13 175 1.2E-58 T 28-03-2018 MKLM6_RS00955 7014d71a0ac16de128dd4284e1176f0e 257 Gene3D G3DSA:2.60.440.10 176 255 5.4E-25 T 28-03-2018 IPR027462 Z ring-associated protein D, C-terminal domain MKLM6_RS13260 b112e34529edf398f10aa935fc5364e2 580 PIRSF PIRSF000207 8 580 1.4E-229 T 28-03-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MKLM6_RS13260 b112e34529edf398f10aa935fc5364e2 580 Pfam PF00258 Flavodoxin 48 171 9.6E-30 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MKLM6_RS13260 b112e34529edf398f10aa935fc5364e2 580 Pfam PF00667 FAD binding domain 210 405 2.1E-34 T 28-03-2018 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 MKLM6_RS13260 b112e34529edf398f10aa935fc5364e2 580 SUPERFAMILY SSF63380 206 427 1.55E-63 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MKLM6_RS13260 b112e34529edf398f10aa935fc5364e2 580 Gene3D G3DSA:3.40.50.80 434 580 3.1E-37 T 28-03-2018 MKLM6_RS13260 b112e34529edf398f10aa935fc5364e2 580 SUPERFAMILY SSF52218 45 187 1.99E-44 T 28-03-2018 IPR029039 Flavoprotein-like domain MKLM6_RS13260 b112e34529edf398f10aa935fc5364e2 580 Gene3D G3DSA:3.40.50.360 27 199 3.0E-38 T 28-03-2018 IPR029039 Flavoprotein-like domain MKLM6_RS13260 b112e34529edf398f10aa935fc5364e2 580 Pfam PF00175 Oxidoreductase NAD-binding domain 438 544 3.7E-17 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MKLM6_RS13260 b112e34529edf398f10aa935fc5364e2 580 SUPERFAMILY SSF52343 425 580 1.31E-50 T 28-03-2018 MKLM6_RS13260 b112e34529edf398f10aa935fc5364e2 580 PRINTS PR00369 Flavodoxin signature 95 106 3.8E-13 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MKLM6_RS13260 b112e34529edf398f10aa935fc5364e2 580 PRINTS PR00369 Flavodoxin signature 47 60 3.8E-13 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MKLM6_RS13260 b112e34529edf398f10aa935fc5364e2 580 PRINTS PR00369 Flavodoxin signature 127 137 3.8E-13 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MKLM6_RS13260 b112e34529edf398f10aa935fc5364e2 580 PRINTS PR00369 Flavodoxin signature 151 170 3.8E-13 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MKLM6_RS13260 b112e34529edf398f10aa935fc5364e2 580 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 400 409 7.3E-30 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MKLM6_RS13260 b112e34529edf398f10aa935fc5364e2 580 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 529 537 7.3E-30 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MKLM6_RS13260 b112e34529edf398f10aa935fc5364e2 580 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 437 456 7.3E-30 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MKLM6_RS13260 b112e34529edf398f10aa935fc5364e2 580 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 462 471 7.3E-30 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MKLM6_RS13260 b112e34529edf398f10aa935fc5364e2 580 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 367 374 7.3E-30 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MKLM6_RS13260 b112e34529edf398f10aa935fc5364e2 580 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 248 258 7.3E-30 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MKLM6_RS13260 b112e34529edf398f10aa935fc5364e2 580 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 475 486 7.3E-30 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MKLM6_RS13260 b112e34529edf398f10aa935fc5364e2 580 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 506 522 7.3E-30 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MKLM6_RS13260 b112e34529edf398f10aa935fc5364e2 580 Gene3D G3DSA:2.40.30.10 200 419 1.6E-50 T 28-03-2018 MKLM6_RS18815 a2d0bfb46bc69b66d8a734037a6231a2 361 Pfam PF02119 Flagellar P-ring protein 20 360 8.4E-137 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MKLM6_RS18815 a2d0bfb46bc69b66d8a734037a6231a2 361 Hamap MF_00416 Flagellar P-ring protein [flgI]. 2 361 38.248 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MKLM6_RS18815 a2d0bfb46bc69b66d8a734037a6231a2 361 PRINTS PR01010 Flagellar P-ring protein signature 78 97 1.5E-78 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MKLM6_RS18815 a2d0bfb46bc69b66d8a734037a6231a2 361 PRINTS PR01010 Flagellar P-ring protein signature 117 135 1.5E-78 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MKLM6_RS18815 a2d0bfb46bc69b66d8a734037a6231a2 361 PRINTS PR01010 Flagellar P-ring protein signature 158 176 1.5E-78 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MKLM6_RS18815 a2d0bfb46bc69b66d8a734037a6231a2 361 PRINTS PR01010 Flagellar P-ring protein signature 248 260 1.5E-78 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MKLM6_RS18815 a2d0bfb46bc69b66d8a734037a6231a2 361 PRINTS PR01010 Flagellar P-ring protein signature 52 67 1.5E-78 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MKLM6_RS18815 a2d0bfb46bc69b66d8a734037a6231a2 361 PRINTS PR01010 Flagellar P-ring protein signature 184 202 1.5E-78 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MKLM6_RS18815 a2d0bfb46bc69b66d8a734037a6231a2 361 PRINTS PR01010 Flagellar P-ring protein signature 20 35 1.5E-78 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MKLM6_RS18815 a2d0bfb46bc69b66d8a734037a6231a2 361 PRINTS PR01010 Flagellar P-ring protein signature 35 50 1.5E-78 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MKLM6_RS18815 a2d0bfb46bc69b66d8a734037a6231a2 361 PRINTS PR01010 Flagellar P-ring protein signature 100 117 1.5E-78 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MKLM6_RS01420 9238710aed0351d7065c5915769762e7 325 SUPERFAMILY SSF54285 1 66 7.36E-16 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MKLM6_RS01420 9238710aed0351d7065c5915769762e7 325 SUPERFAMILY SSF110399 69 311 7.72E-89 T 28-03-2018 MKLM6_RS01420 9238710aed0351d7065c5915769762e7 325 Pfam PF05690 Thiazole biosynthesis protein ThiG 73 319 1.7E-110 T 28-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 MKLM6_RS01420 9238710aed0351d7065c5915769762e7 325 Gene3D G3DSA:3.10.20.30 1 66 8.2E-22 T 28-03-2018 IPR012675 Beta-grasp domain MKLM6_RS01420 9238710aed0351d7065c5915769762e7 325 Hamap MF_00443 Thiazole synthase [thiG]. 70 325 42.364 T 28-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 MKLM6_RS01420 9238710aed0351d7065c5915769762e7 325 Pfam PF02597 ThiS family 3 66 1.5E-13 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 MKLM6_RS01420 9238710aed0351d7065c5915769762e7 325 Gene3D G3DSA:3.20.20.70 68 325 2.1E-49 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS01420 9238710aed0351d7065c5915769762e7 325 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 8.7E-20 T 28-03-2018 IPR010035 ThiS, thiamine-biosynthesis MKLM6_RS01065 1f0188f74780cb3d4aa83d534c27ebbd 319 Gene3D G3DSA:3.40.109.10 146 319 6.0E-26 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MKLM6_RS01065 1f0188f74780cb3d4aa83d534c27ebbd 319 Pfam PF00881 Nitroreductase family 235 295 3.0E-6 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MKLM6_RS01065 1f0188f74780cb3d4aa83d534c27ebbd 319 Pfam PF00881 Nitroreductase family 152 206 3.8E-8 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MKLM6_RS01065 1f0188f74780cb3d4aa83d534c27ebbd 319 SUPERFAMILY SSF55469 150 317 5.89E-27 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MKLM6_RS04465 7db69aa6779583930f5a351974c600f6 325 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 3 322 2.3E-156 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MKLM6_RS04465 7db69aa6779583930f5a351974c600f6 325 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 148 7.0E-66 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MKLM6_RS04465 7db69aa6779583930f5a351974c600f6 325 Gene3D G3DSA:3.90.226.10 28 324 1.7E-68 T 28-03-2018 MKLM6_RS04465 7db69aa6779583930f5a351974c600f6 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 169 182 4.5E-48 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MKLM6_RS04465 7db69aa6779583930f5a351974c600f6 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 153 166 4.5E-48 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MKLM6_RS04465 7db69aa6779583930f5a351974c600f6 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 134 150 4.5E-48 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MKLM6_RS04465 7db69aa6779583930f5a351974c600f6 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 197 206 4.5E-48 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MKLM6_RS04465 7db69aa6779583930f5a351974c600f6 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 88 99 4.5E-48 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MKLM6_RS04465 7db69aa6779583930f5a351974c600f6 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 113 131 4.5E-48 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MKLM6_RS04465 7db69aa6779583930f5a351974c600f6 325 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 319 49.854 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MKLM6_RS04465 7db69aa6779583930f5a351974c600f6 325 SUPERFAMILY SSF52096 6 319 7.85E-101 T 28-03-2018 IPR029045 ClpP/crotonase-like domain MKLM6_RS13000 3da650a6a5bc5d465ccd3f0ce7b70316 324 Gene3D G3DSA:3.90.550.10 9 240 8.0E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS13000 3da650a6a5bc5d465ccd3f0ce7b70316 324 SUPERFAMILY SSF53448 9 241 4.08E-36 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS13000 3da650a6a5bc5d465ccd3f0ce7b70316 324 Pfam PF00535 Glycosyl transferase family 2 14 156 3.4E-22 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MKLM6_RS00445 0808b2f1b4b89f2fe54250954689fe94 198 SUPERFAMILY SSF52980 5 177 5.36E-23 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MKLM6_RS00445 0808b2f1b4b89f2fe54250954689fe94 198 Pfam PF05685 Putative restriction endonuclease 13 163 1.0E-28 T 28-03-2018 IPR008538 Domain of unknown function DUF820 MKLM6_RS00445 0808b2f1b4b89f2fe54250954689fe94 198 Gene3D G3DSA:3.90.1570.10 1 181 7.5E-41 T 28-03-2018 MKLM6_RS08475 ff0b1340ec8b6f0e0ec999a0bb214f89 147 PIRSF PIRSF001263 1 147 7.4E-51 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MKLM6_RS08475 ff0b1340ec8b6f0e0ec999a0bb214f89 147 SUPERFAMILY SSF55234 80 147 2.48E-30 T 28-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MKLM6_RS08475 ff0b1340ec8b6f0e0ec999a0bb214f89 147 TIGRFAM TIGR00673 cynS: cyanase 4 147 5.2E-51 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MKLM6_RS08475 ff0b1340ec8b6f0e0ec999a0bb214f89 147 Hamap MF_00535 Cyanate hydratase [cynS]. 1 147 83.389 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MKLM6_RS08475 ff0b1340ec8b6f0e0ec999a0bb214f89 147 Pfam PF02560 Cyanate lyase C-terminal domain 79 145 6.2E-36 T 28-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MKLM6_RS08475 ff0b1340ec8b6f0e0ec999a0bb214f89 147 Gene3D G3DSA:3.30.1160.10 81 146 2.6E-37 T 28-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MKLM6_RS08475 ff0b1340ec8b6f0e0ec999a0bb214f89 147 PRINTS PR01693 Cyanase signature 101 117 2.3E-28 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MKLM6_RS08475 ff0b1340ec8b6f0e0ec999a0bb214f89 147 PRINTS PR01693 Cyanase signature 34 51 2.3E-28 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MKLM6_RS08475 ff0b1340ec8b6f0e0ec999a0bb214f89 147 PRINTS PR01693 Cyanase signature 83 97 2.3E-28 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MKLM6_RS08475 ff0b1340ec8b6f0e0ec999a0bb214f89 147 PRINTS PR01693 Cyanase signature 14 29 2.3E-28 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MKLM6_RS08475 ff0b1340ec8b6f0e0ec999a0bb214f89 147 PRINTS PR01693 Cyanase signature 132 142 2.3E-28 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MKLM6_RS08475 ff0b1340ec8b6f0e0ec999a0bb214f89 147 SMART SM01116 75 147 1.4E-50 T 28-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MKLM6_RS08475 ff0b1340ec8b6f0e0ec999a0bb214f89 147 SUPERFAMILY SSF47413 1 77 5.63E-21 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MKLM6_RS08475 ff0b1340ec8b6f0e0ec999a0bb214f89 147 Gene3D G3DSA:1.10.260.40 1 80 2.8E-9 T 28-03-2018 MKLM6_RS04995 b618d5d6f738b0073840ae339a03c2c1 320 Pfam PF04016 Putative heavy-metal chelation 113 249 9.5E-39 T 28-03-2018 IPR007161 Putative heavy-metal chelation domain MKLM6_RS04995 b618d5d6f738b0073840ae339a03c2c1 320 Pfam PF13938 Putative heavy-metal chelation 8 90 1.9E-18 T 28-03-2018 IPR025251 Domain of unknown function DUF4213 MKLM6_RS04995 b618d5d6f738b0073840ae339a03c2c1 320 SUPERFAMILY SSF159713 6 248 2.75E-66 T 28-03-2018 MKLM6_RS01980 7dfbbd7f27d809b78b8403113976e1a5 943 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 16 848 5.6E-292 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MKLM6_RS01980 7dfbbd7f27d809b78b8403113976e1a5 943 SUPERFAMILY SSF50677 205 410 1.83E-54 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MKLM6_RS01980 7dfbbd7f27d809b78b8403113976e1a5 943 Gene3D G3DSA:3.90.740.10 210 401 6.6E-67 T 28-03-2018 MKLM6_RS01980 7dfbbd7f27d809b78b8403113976e1a5 943 Gene3D G3DSA:3.40.50.620 402 635 7.7E-74 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS01980 7dfbbd7f27d809b78b8403113976e1a5 943 SUPERFAMILY SSF47323 658 934 1.76E-72 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS01980 7dfbbd7f27d809b78b8403113976e1a5 943 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 29 646 1.3E-216 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS01980 7dfbbd7f27d809b78b8403113976e1a5 943 Pfam PF08264 Anticodon-binding domain of tRNA 691 847 1.3E-25 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 MKLM6_RS01980 7dfbbd7f27d809b78b8403113976e1a5 943 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 3 934 21.653 T 28-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 MKLM6_RS01980 7dfbbd7f27d809b78b8403113976e1a5 943 Gene3D G3DSA:3.40.50.620 48 209 8.9E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS01980 7dfbbd7f27d809b78b8403113976e1a5 943 SUPERFAMILY SSF52374 3 203 3.9E-144 T 28-03-2018 MKLM6_RS01980 7dfbbd7f27d809b78b8403113976e1a5 943 SUPERFAMILY SSF52374 410 654 3.9E-144 T 28-03-2018 MKLM6_RS01980 7dfbbd7f27d809b78b8403113976e1a5 943 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 408 423 2.0E-33 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MKLM6_RS01980 7dfbbd7f27d809b78b8403113976e1a5 943 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 242 265 2.0E-33 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MKLM6_RS01980 7dfbbd7f27d809b78b8403113976e1a5 943 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 533 546 2.0E-33 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MKLM6_RS01980 7dfbbd7f27d809b78b8403113976e1a5 943 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 567 576 2.0E-33 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MKLM6_RS01980 7dfbbd7f27d809b78b8403113976e1a5 943 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 52 63 2.0E-33 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MKLM6_RS01980 7dfbbd7f27d809b78b8403113976e1a5 943 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 59 70 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS01980 7dfbbd7f27d809b78b8403113976e1a5 943 Gene3D G3DSA:1.10.730.10 636 800 5.5E-31 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS01980 7dfbbd7f27d809b78b8403113976e1a5 943 Gene3D G3DSA:3.30.2320.20 808 901 2.9E-21 T 28-03-2018 MKLM6_RS08215 32d23338730aa6078e4305ab97792e40 487 Gene3D G3DSA:3.40.720.10 37 478 5.4E-19 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MKLM6_RS08215 32d23338730aa6078e4305ab97792e40 487 SUPERFAMILY SSF53649 295 474 8.11E-20 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MKLM6_RS08215 32d23338730aa6078e4305ab97792e40 487 Pfam PF07394 Protein of unknown function (DUF1501) 62 486 1.8E-131 T 28-03-2018 IPR010869 Protein of unknown function DUF1501 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 Gene3D G3DSA:1.25.40.10 570 640 1.7E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 TIGRFAM TIGR02917 PEP_TPR_lipo: putative PEP-CTERM system TPR-repeat lipoprotein 35 918 2.4E-173 T 28-03-2018 IPR014266 PEP-CTERM system TPR-repeat lipoprotein, putative MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 Gene3D G3DSA:1.25.40.10 402 447 0.011 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 Gene3D G3DSA:1.10.287.1110 225 236 2.5E-4 T 28-03-2018 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 Gene3D G3DSA:1.10.287.1110 504 517 2.5E-4 T 28-03-2018 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 Gene3D G3DSA:1.25.40.10 363 401 2.3E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SUPERFAMILY SSF48452 36 118 9.87E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 Pfam PF13181 Tetratricopeptide repeat 206 237 6.7E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SUPERFAMILY SSF48452 317 479 5.84E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 Gene3D G3DSA:1.25.40.10 33 128 2.8E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 Pfam PF13432 Tetratricopeptide repeat 142 203 2.9E-4 T 28-03-2018 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 Gene3D G3DSA:1.25.40.10 851 938 1.4E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SUPERFAMILY SSF48452 461 645 1.63E-23 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SUPERFAMILY SSF48452 655 839 6.64E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 Gene3D G3DSA:1.25.40.10 641 783 1.4E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 Gene3D G3DSA:1.25.40.10 237 303 8.5E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 Gene3D G3DSA:1.25.40.10 518 569 3.6E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 Gene3D G3DSA:1.25.40.10 448 503 2.1E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SMART SM00028 136 169 0.0065 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SMART SM00028 314 347 370.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SMART SM00028 484 517 6.7E-5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SMART SM00028 654 687 9.5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SMART SM00028 68 101 240.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SMART SM00028 348 381 53.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SMART SM00028 552 585 110.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SMART SM00028 722 755 120.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SMART SM00028 382 415 100.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SMART SM00028 34 67 74.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SMART SM00028 238 271 330.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SMART SM00028 204 237 4.8E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SMART SM00028 824 856 39.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SMART SM00028 790 823 14.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SMART SM00028 891 924 8.7 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SMART SM00028 170 203 18.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SMART SM00028 416 449 110.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SMART SM00028 857 890 470.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SUPERFAMILY SSF48452 795 921 8.35E-22 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 Gene3D G3DSA:1.25.40.10 784 850 5.9E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 Pfam PF13429 Tetratricopeptide repeat 757 921 1.4E-6 T 28-03-2018 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 Gene3D G3DSA:1.25.40.10 129 224 1.6E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 SUPERFAMILY SSF48452 137 301 4.25E-26 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 Gene3D G3DSA:1.25.40.10 304 362 3.6E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 Pfam PF14559 Tetratricopeptide repeat 461 517 3.0E-6 T 28-03-2018 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 Pfam PF14559 Tetratricopeptide repeat 530 582 7.8E-7 T 28-03-2018 MKLM6_RS13770 ea51863de8557ee5ac93dcc711dfc63c 938 Pfam PF14559 Tetratricopeptide repeat 328 389 3.5E-6 T 28-03-2018 MKLM6_RS21355 6b13f3b708b13da9b23d90917ab50453 284 Gene3D G3DSA:3.30.950.10 113 227 1.5E-36 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MKLM6_RS21355 6b13f3b708b13da9b23d90917ab50453 284 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 5 276 3.7E-83 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MKLM6_RS21355 6b13f3b708b13da9b23d90917ab50453 284 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 82 93 - T 28-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MKLM6_RS21355 6b13f3b708b13da9b23d90917ab50453 284 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 204 2.3E-28 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MKLM6_RS21355 6b13f3b708b13da9b23d90917ab50453 284 PIRSF PIRSF005917 1 280 2.1E-101 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MKLM6_RS21355 6b13f3b708b13da9b23d90917ab50453 284 Gene3D G3DSA:3.40.1010.10 2 112 2.3E-40 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MKLM6_RS21355 6b13f3b708b13da9b23d90917ab50453 284 SUPERFAMILY SSF53790 2 222 1.57E-77 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MKLM6_RS21355 6b13f3b708b13da9b23d90917ab50453 284 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 4 225 36.717 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MKLM6_RS01595 3e3df61586ea6632b695ffa2fd9cd207 247 SUPERFAMILY SSF51366 1 235 3.38E-73 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MKLM6_RS01595 3e3df61586ea6632b695ffa2fd9cd207 247 Pfam PF00977 Histidine biosynthesis protein 3 231 2.6E-79 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 MKLM6_RS01595 3e3df61586ea6632b695ffa2fd9cd207 247 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 239 36.217 T 28-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 MKLM6_RS01595 3e3df61586ea6632b695ffa2fd9cd207 247 Gene3D G3DSA:3.20.20.70 2 242 9.4E-59 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS01595 3e3df61586ea6632b695ffa2fd9cd207 247 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 234 7.8E-79 T 28-03-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 MKLM6_RS07240 bd5f1a8aa70828a31f5b8d1634f73cfe 189 Pfam PF01132 Elongation factor P (EF-P) OB domain 70 123 5.8E-22 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 MKLM6_RS07240 bd5f1a8aa70828a31f5b8d1634f73cfe 189 Hamap MF_00141 Elongation factor P [efp]. 3 187 50.042 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 MKLM6_RS07240 bd5f1a8aa70828a31f5b8d1634f73cfe 189 ProSitePatterns PS01275 Elongation factor P signature. 152 171 - T 28-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site MKLM6_RS07240 bd5f1a8aa70828a31f5b8d1634f73cfe 189 SUPERFAMILY SSF50249 130 187 5.65E-19 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS07240 bd5f1a8aa70828a31f5b8d1634f73cfe 189 SMART SM00841 131 186 4.9E-34 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 MKLM6_RS07240 bd5f1a8aa70828a31f5b8d1634f73cfe 189 Pfam PF09285 Elongation factor P, C-terminal 131 186 6.8E-27 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 MKLM6_RS07240 bd5f1a8aa70828a31f5b8d1634f73cfe 189 Gene3D G3DSA:2.40.50.140 67 129 4.6E-25 T 28-03-2018 MKLM6_RS07240 bd5f1a8aa70828a31f5b8d1634f73cfe 189 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 5 62 8.5E-27 T 28-03-2018 IPR013185 Translation elongation factor, KOW-like MKLM6_RS07240 bd5f1a8aa70828a31f5b8d1634f73cfe 189 Gene3D G3DSA:2.40.50.140 131 186 1.3E-28 T 28-03-2018 MKLM6_RS07240 bd5f1a8aa70828a31f5b8d1634f73cfe 189 TIGRFAM TIGR00038 efp: translation elongation factor P 5 187 1.8E-79 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 MKLM6_RS07240 bd5f1a8aa70828a31f5b8d1634f73cfe 189 Gene3D G3DSA:2.30.30.30 4 63 2.9E-25 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 MKLM6_RS07240 bd5f1a8aa70828a31f5b8d1634f73cfe 189 SMART SM01185 69 123 9.7E-25 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 MKLM6_RS07240 bd5f1a8aa70828a31f5b8d1634f73cfe 189 SUPERFAMILY SSF50249 69 128 1.33E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS07240 bd5f1a8aa70828a31f5b8d1634f73cfe 189 SUPERFAMILY SSF50104 2 63 3.31E-21 T 28-03-2018 IPR008991 Translation protein SH3-like domain MKLM6_RS07240 bd5f1a8aa70828a31f5b8d1634f73cfe 189 PIRSF PIRSF005901 2 188 1.3E-68 T 28-03-2018 IPR020599 Translation elongation factor P/YeiP MKLM6_RS12030 aecfa173919cc60687de0944523dfed1 248 Gene3D G3DSA:3.40.190.10 11 89 0.0015 T 28-03-2018 MKLM6_RS12030 aecfa173919cc60687de0944523dfed1 248 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 5 235 9.8E-35 T 28-03-2018 MKLM6_RS12030 aecfa173919cc60687de0944523dfed1 248 Gene3D G3DSA:3.40.190.10 90 232 1.6E-8 T 28-03-2018 MKLM6_RS12030 aecfa173919cc60687de0944523dfed1 248 SUPERFAMILY SSF53850 20 177 8.52E-15 T 28-03-2018 MKLM6_RS02920 98f85a33b4343b71d63fd256638a01d3 347 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 3 337 49.546 T 28-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 MKLM6_RS02920 98f85a33b4343b71d63fd256638a01d3 347 SUPERFAMILY SSF51395 4 337 2.6E-103 T 28-03-2018 MKLM6_RS02920 98f85a33b4343b71d63fd256638a01d3 347 Gene3D G3DSA:3.20.20.70 2 338 8.0E-84 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS02920 98f85a33b4343b71d63fd256638a01d3 347 Pfam PF01180 Dihydroorotate dehydrogenase 47 338 3.7E-94 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 MKLM6_RS02920 98f85a33b4343b71d63fd256638a01d3 347 PIRSF PIRSF000164 14 346 5.6E-96 T 28-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 MKLM6_RS02920 98f85a33b4343b71d63fd256638a01d3 347 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 4 337 1.9E-132 T 28-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 MKLM6_RS02920 98f85a33b4343b71d63fd256638a01d3 347 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 81 100 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 MKLM6_RS09080 9bfdf37aa0366d3523fe8fd4d7351009 226 Gene3D G3DSA:3.20.20.70 130 226 2.2E-7 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS09080 9bfdf37aa0366d3523fe8fd4d7351009 226 SUPERFAMILY SSF51366 1 223 1.35E-23 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MKLM6_RS09080 9bfdf37aa0366d3523fe8fd4d7351009 226 Pfam PF00977 Histidine biosynthesis protein 2 218 5.9E-19 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 MKLM6_RS09080 9bfdf37aa0366d3523fe8fd4d7351009 226 Gene3D G3DSA:3.20.20.70 1 100 3.0E-5 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS09730 3add07bd04b72a7e1416612526413bae 241 Pfam PF13545 Crp-like helix-turn-helix domain 151 216 6.7E-12 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MKLM6_RS09730 3add07bd04b72a7e1416612526413bae 241 Gene3D G3DSA:2.60.120.10 3 152 9.8E-8 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS09730 3add07bd04b72a7e1416612526413bae 241 SUPERFAMILY SSF46785 149 222 1.74E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS09730 3add07bd04b72a7e1416612526413bae 241 SUPERFAMILY SSF51206 11 136 5.89E-8 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like MKLM6_RS09730 3add07bd04b72a7e1416612526413bae 241 Gene3D G3DSA:1.10.10.10 153 236 1.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS04385 9a338dd0253870a49fb0859f717a4371 347 Gene3D G3DSA:1.10.443.10 168 343 7.7E-43 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS04385 9a338dd0253870a49fb0859f717a4371 347 Gene3D G3DSA:1.10.150.130 58 167 9.7E-19 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal MKLM6_RS04385 9a338dd0253870a49fb0859f717a4371 347 SUPERFAMILY SSF56349 64 331 1.06E-64 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS04385 9a338dd0253870a49fb0859f717a4371 347 Pfam PF00589 Phage integrase family 167 328 1.4E-31 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS16085 403d78a6cb873a865660e1e4b7efcdda 427 SUPERFAMILY SSF56059 284 411 3.53E-8 T 28-03-2018 MKLM6_RS16085 403d78a6cb873a865660e1e4b7efcdda 427 SUPERFAMILY SSF56059 100 183 3.53E-8 T 28-03-2018 MKLM6_RS03735 b710b9938fe04ce8b7eb04ea02f78c35 263 Pfam PF00398 Ribosomal RNA adenine dimethylase 3 254 1.6E-63 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm MKLM6_RS03735 b710b9938fe04ce8b7eb04ea02f78c35 263 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 4 256 2.0E-84 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 MKLM6_RS03735 b710b9938fe04ce8b7eb04ea02f78c35 263 Gene3D G3DSA:3.40.50.150 1 198 9.9E-58 T 28-03-2018 MKLM6_RS03735 b710b9938fe04ce8b7eb04ea02f78c35 263 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 3 258 56.758 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 MKLM6_RS03735 b710b9938fe04ce8b7eb04ea02f78c35 263 SMART SM00650 19 191 1.9E-82 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 MKLM6_RS03735 b710b9938fe04ce8b7eb04ea02f78c35 263 SUPERFAMILY SSF53335 3 258 4.18E-78 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS03735 b710b9938fe04ce8b7eb04ea02f78c35 263 Gene3D G3DSA:1.10.8.100 199 257 1.6E-18 T 28-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 MKLM6_RS07465 9a0ea5110828cf159453113eb4553e74 286 SUPERFAMILY SSF51182 4 285 6.64E-80 T 28-03-2018 IPR011051 RmlC-like cupin domain MKLM6_RS07465 9a0ea5110828cf159453113eb4553e74 286 PIRSF PIRSF006232 2 286 3.0E-86 T 28-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 MKLM6_RS07465 9a0ea5110828cf159453113eb4553e74 286 Pfam PF02678 Pirin 21 127 8.2E-33 T 28-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 MKLM6_RS07465 9a0ea5110828cf159453113eb4553e74 286 Gene3D G3DSA:2.60.120.10 1 257 1.0E-78 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS07465 9a0ea5110828cf159453113eb4553e74 286 Pfam PF05726 Pirin C-terminal cupin domain 182 284 2.7E-26 T 28-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 MKLM6_RS02525 19f640d0e7a480882e4c8701362e445d 162 SUPERFAMILY SSF103642 136 156 1.8E-7 T 28-03-2018 MKLM6_RS02525 19f640d0e7a480882e4c8701362e445d 162 Pfam PF02810 SEC-C motif 3 18 3.3E-4 T 28-03-2018 IPR004027 SEC-C motif MKLM6_RS02525 19f640d0e7a480882e4c8701362e445d 162 Pfam PF02810 SEC-C motif 139 156 1.9E-9 T 28-03-2018 IPR004027 SEC-C motif MKLM6_RS02525 19f640d0e7a480882e4c8701362e445d 162 SUPERFAMILY SSF54427 23 124 2.55E-30 T 28-03-2018 IPR032710 NTF2-like domain MKLM6_RS02525 19f640d0e7a480882e4c8701362e445d 162 Gene3D G3DSA:3.10.450.50 2 126 3.1E-38 T 28-03-2018 MKLM6_RS20785 564df4b465a11ee5c18deadb156de1f0 642 SUPERFAMILY SSF52540 43 143 1.82E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS20785 564df4b465a11ee5c18deadb156de1f0 642 SUPERFAMILY SSF52540 189 359 1.82E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS20785 564df4b465a11ee5c18deadb156de1f0 642 Pfam PF00350 Dynamin family 60 258 1.5E-12 T 28-03-2018 IPR022812 Dynamin superfamily MKLM6_RS20785 564df4b465a11ee5c18deadb156de1f0 642 Gene3D G3DSA:3.40.50.300 39 596 1.8E-30 T 28-03-2018 MKLM6_RS04290 368e3b2d9131ab5afefae81222ccc4a6 934 Gene3D G3DSA:3.40.50.300 399 586 4.7E-7 T 28-03-2018 MKLM6_RS04290 368e3b2d9131ab5afefae81222ccc4a6 934 SUPERFAMILY SSF52540 234 278 1.93E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS04290 368e3b2d9131ab5afefae81222ccc4a6 934 SUPERFAMILY SSF52540 395 450 1.93E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS04290 368e3b2d9131ab5afefae81222ccc4a6 934 SUPERFAMILY SSF52540 134 187 1.93E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS04290 368e3b2d9131ab5afefae81222ccc4a6 934 SUPERFAMILY SSF52540 501 578 1.93E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS04290 368e3b2d9131ab5afefae81222ccc4a6 934 SUPERFAMILY SSF52540 307 321 1.93E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS04290 368e3b2d9131ab5afefae81222ccc4a6 934 Gene3D G3DSA:3.40.1350.10 761 909 2.4E-9 T 28-03-2018 MKLM6_RS04290 368e3b2d9131ab5afefae81222ccc4a6 934 Gene3D G3DSA:3.40.50.300 88 329 1.6E-11 T 28-03-2018 MKLM6_RS04290 368e3b2d9131ab5afefae81222ccc4a6 934 Pfam PF04851 Type III restriction enzyme, res subunit 94 318 2.9E-14 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MKLM6_RS13450 324076ca9839725091b6539374b6c684 462 Gene3D G3DSA:1.20.5.1040 127 186 2.0E-5 T 28-03-2018 MKLM6_RS13450 324076ca9839725091b6539374b6c684 462 Gene3D G3DSA:1.20.5.1040 5 55 1.3E-4 T 28-03-2018 MKLM6_RS13450 324076ca9839725091b6539374b6c684 462 SUPERFAMILY SSF55874 309 454 4.19E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13450 324076ca9839725091b6539374b6c684 462 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 351 453 1.7E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13450 324076ca9839725091b6539374b6c684 462 Gene3D G3DSA:3.30.565.10 311 461 1.9E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13450 324076ca9839725091b6539374b6c684 462 Pfam PF08521 Two-component sensor kinase N-terminal 19 162 3.3E-39 T 28-03-2018 IPR013727 Two-component sensor kinase, N-terminal MKLM6_RS13450 324076ca9839725091b6539374b6c684 462 Gene3D G3DSA:1.10.287.130 220 299 1.2E-9 T 28-03-2018 MKLM6_RS13450 324076ca9839725091b6539374b6c684 462 SUPERFAMILY SSF47384 222 301 3.53E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS13450 324076ca9839725091b6539374b6c684 462 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 414 3.4E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13450 324076ca9839725091b6539374b6c684 462 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 400 3.4E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13450 324076ca9839725091b6539374b6c684 462 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 436 3.4E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13450 324076ca9839725091b6539374b6c684 462 SMART SM00388 239 304 1.0E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS13450 324076ca9839725091b6539374b6c684 462 SMART SM00387 351 459 2.2E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13450 324076ca9839725091b6539374b6c684 462 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 299 9.0E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS20835 ed3a21801f391d854f4e6d743698481e 97 Pfam PF13466 STAS domain 4 82 1.4E-14 T 28-03-2018 IPR002645 STAS domain MKLM6_RS20835 ed3a21801f391d854f4e6d743698481e 97 Gene3D G3DSA:3.30.750.24 1 96 8.8E-11 T 28-03-2018 IPR002645 STAS domain MKLM6_RS20835 ed3a21801f391d854f4e6d743698481e 97 SUPERFAMILY SSF52091 2 87 1.81E-14 T 28-03-2018 IPR002645 STAS domain MKLM6_RS15020 1cfb0dd561e2be3f992941763660cd66 833 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 671 683 - T 28-03-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 MKLM6_RS15020 1cfb0dd561e2be3f992941763660cd66 833 Gene3D G3DSA:3.40.50.2000 15 496 9.2E-207 T 28-03-2018 MKLM6_RS15020 1cfb0dd561e2be3f992941763660cd66 833 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 26 826 0.0 T 28-03-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 MKLM6_RS15020 1cfb0dd561e2be3f992941763660cd66 833 PIRSF PIRSF000460 12 833 1.6E-224 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 MKLM6_RS15020 1cfb0dd561e2be3f992941763660cd66 833 SUPERFAMILY SSF53756 21 831 0.0 T 28-03-2018 MKLM6_RS15020 1cfb0dd561e2be3f992941763660cd66 833 Pfam PF00343 Carbohydrate phosphorylase 113 826 0.0 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 MKLM6_RS15020 1cfb0dd561e2be3f992941763660cd66 833 Gene3D G3DSA:3.40.50.2000 497 811 1.5E-134 T 28-03-2018 MKLM6_RS10765 8afe36924f6991cc09e88bf292d1bb03 583 Pfam PF11845 Protein of unknown function (DUF3365) 21 216 1.2E-30 T 28-03-2018 IPR021796 Protein of unknown function DUF3365 MKLM6_RS10765 8afe36924f6991cc09e88bf292d1bb03 583 SMART SM00283 321 582 4.0E-88 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS10765 8afe36924f6991cc09e88bf292d1bb03 583 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 365 549 1.4E-44 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS10765 8afe36924f6991cc09e88bf292d1bb03 583 SUPERFAMILY SSF58104 274 583 1.05E-80 T 28-03-2018 MKLM6_RS10765 8afe36924f6991cc09e88bf292d1bb03 583 SMART SM00304 252 306 5.2E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS10765 8afe36924f6991cc09e88bf292d1bb03 583 Gene3D G3DSA:1.10.287.950 355 583 7.0E-56 T 28-03-2018 MKLM6_RS10765 8afe36924f6991cc09e88bf292d1bb03 583 Gene3D G3DSA:1.10.287.950 220 354 7.1E-8 T 28-03-2018 MKLM6_RS02445 bdfca41779ad3c492fa43efd613c5668 186 Pfam PF09186 Domain of unknown function (DUF1949) 137 186 1.5E-8 T 28-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal MKLM6_RS02445 bdfca41779ad3c492fa43efd613c5668 186 SUPERFAMILY SSF54211 3 129 2.5E-38 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS02445 bdfca41779ad3c492fa43efd613c5668 186 SUPERFAMILY SSF54980 134 185 3.45E-8 T 28-03-2018 IPR035647 EF-G domain III/V-like MKLM6_RS02445 bdfca41779ad3c492fa43efd613c5668 186 Gene3D G3DSA:3.30.70.240 132 186 5.0E-10 T 28-03-2018 MKLM6_RS02445 bdfca41779ad3c492fa43efd613c5668 186 Gene3D G3DSA:3.30.230.30 1 130 1.6E-39 T 28-03-2018 IPR001498 Impact, N-terminal MKLM6_RS02445 bdfca41779ad3c492fa43efd613c5668 186 Pfam PF01205 Uncharacterized protein family UPF0029 15 121 7.4E-29 T 28-03-2018 IPR001498 Impact, N-terminal MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 Gene3D G3DSA:1.25.40.10 338 431 5.3E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 Gene3D G3DSA:1.25.40.10 512 573 2.0E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 Gene3D G3DSA:1.25.40.10 300 337 1.9E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 SUPERFAMILY SSF48452 392 560 3.13E-27 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 SUPERFAMILY SSF48452 172 348 2.2E-20 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 Gene3D G3DSA:1.25.40.10 273 299 3.2E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 Gene3D G3DSA:1.25.40.10 432 480 7.9E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 Gene3D G3DSA:1.25.40.10 36 217 7.7E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 Gene3D G3DSA:1.25.40.10 218 272 1.1E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 Gene3D G3DSA:1.20.58.280 481 511 3.8E-8 T 28-03-2018 MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 SMART SM00028 390 423 0.48 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 SMART SM00028 527 559 130.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 SMART SM00028 288 320 46.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 SMART SM00028 50 83 67.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 SMART SM00028 220 253 3.7 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 SMART SM00028 322 355 190.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 SMART SM00028 458 492 18.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 SMART SM00028 186 219 230.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 SMART SM00028 493 526 13.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 Pfam PF14559 Tetratricopeptide repeat 265 315 7.3E-10 T 28-03-2018 MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 Pfam PF14559 Tetratricopeptide repeat 503 562 2.5E-8 T 28-03-2018 MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 Pfam PF13181 Tetratricopeptide repeat 460 491 0.0011 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 Pfam PF13181 Tetratricopeptide repeat 227 253 0.016 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS18565 1d071f76614ade8abf56f6c9de5a0204 574 Pfam PF13181 Tetratricopeptide repeat 391 423 0.026 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS19435 0249b584965d95b4353057fb09353d54 97 Gene3D G3DSA:3.40.1260.10 1 93 3.6E-14 T 28-03-2018 MKLM6_RS19435 0249b584965d95b4353057fb09353d54 97 TIGRFAM TIGR03011 sulf_tusB_dsrH: sulfur relay protein TusB/DsrH 2 96 4.0E-16 T 28-03-2018 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 MKLM6_RS19435 0249b584965d95b4353057fb09353d54 97 Pfam PF04077 DsrH like protein 13 91 2.1E-13 T 28-03-2018 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 MKLM6_RS19435 0249b584965d95b4353057fb09353d54 97 SUPERFAMILY SSF75169 1 96 1.46E-14 T 28-03-2018 IPR027396 DsrEFH-like MKLM6_RS15845 3ebaf9d83e898d5bb0c6890dc980e93d 258 Gene3D G3DSA:3.90.550.10 1 239 8.2E-23 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS15845 3ebaf9d83e898d5bb0c6890dc980e93d 258 Pfam PF02348 Cytidylyltransferase 4 196 8.3E-31 T 28-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 MKLM6_RS15845 3ebaf9d83e898d5bb0c6890dc980e93d 258 SUPERFAMILY SSF53448 1 207 4.33E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS20310 d5cb7ea2597e1f26006bdfca0a2ad317 1185 TIGRFAM TIGR03348 VI_IcmF: type VI secretion protein IcmF 15 1183 0.0 T 28-03-2018 IPR017731 Type VI secretion system, IcmF MKLM6_RS20310 d5cb7ea2597e1f26006bdfca0a2ad317 1185 Pfam PF14331 ImcF-related N-terminal domain 200 460 7.6E-96 T 28-03-2018 IPR025743 ImcF-related, N-terminal domain MKLM6_RS20310 d5cb7ea2597e1f26006bdfca0a2ad317 1185 SUPERFAMILY SSF52540 130 304 1.15E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS20310 d5cb7ea2597e1f26006bdfca0a2ad317 1185 Pfam PF06744 Type VI secretion protein IcmF C-terminal 937 1133 7.0E-57 T 28-03-2018 IPR010623 Type VI secretion system IcmF, C-terminal MKLM6_RS20310 d5cb7ea2597e1f26006bdfca0a2ad317 1185 Gene3D G3DSA:3.40.50.300 134 363 2.7E-8 T 28-03-2018 MKLM6_RS20310 d5cb7ea2597e1f26006bdfca0a2ad317 1185 Pfam PF06761 Intracellular multiplication and human macrophage-killing 511 809 2.4E-68 T 28-03-2018 IPR009612 ImcF-related MKLM6_RS03200 e511e3e812ca05a46e59e51cd465438e 191 Pfam PF02325 YGGT family 16 83 1.7E-20 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 MKLM6_RS03200 e511e3e812ca05a46e59e51cd465438e 191 Pfam PF02325 YGGT family 110 179 6.9E-19 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 MKLM6_RS16105 b1987168c19c59891b822adfb5e6973e 148 SUPERFAMILY SSF143422 1 138 6.28E-34 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS16105 b1987168c19c59891b822adfb5e6973e 148 Gene3D G3DSA:3.30.70.1290 1 140 7.4E-34 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS16105 b1987168c19c59891b822adfb5e6973e 148 SMART SM01321 9 133 1.2E-35 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS16105 b1987168c19c59891b822adfb5e6973e 148 Pfam PF01797 Transposase IS200 like 22 131 3.7E-12 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS20685 8e395cad3fa1ae167f6f2a0344c6665f 378 SUPERFAMILY SSF111369 47 258 1.31E-17 T 28-03-2018 MKLM6_RS20685 8e395cad3fa1ae167f6f2a0344c6665f 378 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 37 376 5.3E-49 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MKLM6_RS20685 8e395cad3fa1ae167f6f2a0344c6665f 378 Pfam PF00529 HlyD membrane-fusion protein of T1SS 38 360 4.4E-8 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MKLM6_RS20685 8e395cad3fa1ae167f6f2a0344c6665f 378 Gene3D G3DSA:1.20.1600.10 32 288 1.8E-23 T 28-03-2018 MKLM6_RS20685 8e395cad3fa1ae167f6f2a0344c6665f 378 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 56 287 2.3E-21 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MKLM6_RS16950 dfc418beb9a635becddc2924a43ede01 407 Gene3D G3DSA:1.10.3210.10 82 315 1.7E-38 T 28-03-2018 MKLM6_RS16950 dfc418beb9a635becddc2924a43ede01 407 SMART SM00471 147 283 4.7E-7 T 28-03-2018 IPR003607 HD/PDEase domain MKLM6_RS16950 dfc418beb9a635becddc2924a43ede01 407 Pfam PF13487 HD domain 202 264 2.9E-10 T 28-03-2018 MKLM6_RS16950 dfc418beb9a635becddc2924a43ede01 407 Pfam PF11871 Domain of unknown function (DUF3391) 10 118 3.9E-14 T 28-03-2018 IPR021812 Protein of unknown function DUF3391 MKLM6_RS16950 dfc418beb9a635becddc2924a43ede01 407 SUPERFAMILY SSF109604 142 313 1.02E-30 T 28-03-2018 MKLM6_RS00115 03ccec20cdccd4dc332eb859c5a4d02c 186 Gene3D G3DSA:3.10.290.30 1 173 3.8E-52 T 28-03-2018 IPR024047 Protein MM3350-like domain MKLM6_RS00115 03ccec20cdccd4dc332eb859c5a4d02c 186 SUPERFAMILY SSF159941 9 172 2.35E-50 T 28-03-2018 IPR024047 Protein MM3350-like domain MKLM6_RS00115 03ccec20cdccd4dc332eb859c5a4d02c 186 Pfam PF07929 Plasmid pRiA4b ORF-3-like protein 8 168 1.2E-51 T 28-03-2018 IPR012912 Plasmid pRiA4b, Orf3 MKLM6_RS03065 f701217c835b33db3b5dce1e86f89325 359 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 213 241 - T 28-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 MKLM6_RS03065 f701217c835b33db3b5dce1e86f89325 359 SUPERFAMILY SSF53955 193 335 2.57E-28 T 28-03-2018 IPR023346 Lysozyme-like domain MKLM6_RS03065 f701217c835b33db3b5dce1e86f89325 359 Pfam PF01464 Transglycosylase SLT domain 207 301 3.8E-20 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 MKLM6_RS03065 f701217c835b33db3b5dce1e86f89325 359 Gene3D G3DSA:1.10.530.10 175 347 1.2E-28 T 28-03-2018 MKLM6_RS14035 e2b93c3647e3d41afd830f0a6155e4a1 248 Hamap MF_01974 Methionine aminopeptidase [map]. 1 248 32.982 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MKLM6_RS14035 e2b93c3647e3d41afd830f0a6155e4a1 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 66 79 2.7E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MKLM6_RS14035 e2b93c3647e3d41afd830f0a6155e4a1 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 158 170 2.7E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MKLM6_RS14035 e2b93c3647e3d41afd830f0a6155e4a1 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 2.7E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MKLM6_RS14035 e2b93c3647e3d41afd830f0a6155e4a1 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 88 104 2.7E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MKLM6_RS14035 e2b93c3647e3d41afd830f0a6155e4a1 248 Gene3D G3DSA:3.90.230.10 1 248 1.9E-63 T 28-03-2018 MKLM6_RS14035 e2b93c3647e3d41afd830f0a6155e4a1 248 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 1 247 3.3E-78 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MKLM6_RS14035 e2b93c3647e3d41afd830f0a6155e4a1 248 Pfam PF00557 Metallopeptidase family M24 12 239 2.8E-43 T 28-03-2018 IPR000994 Peptidase M24 MKLM6_RS14035 e2b93c3647e3d41afd830f0a6155e4a1 248 SUPERFAMILY SSF55920 3 246 2.22E-65 T 28-03-2018 IPR000994 Peptidase M24 MKLM6_RS19550 17df95233908fdf594ce5c95c5e97a43 198 TIGRFAM TIGR00615 recR: recombination protein RecR 3 196 9.7E-74 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 MKLM6_RS19550 17df95233908fdf594ce5c95c5e97a43 198 Gene3D G3DSA:3.40.1360.10 77 170 4.7E-33 T 28-03-2018 MKLM6_RS19550 17df95233908fdf594ce5c95c5e97a43 198 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 28-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 MKLM6_RS19550 17df95233908fdf594ce5c95c5e97a43 198 SUPERFAMILY SSF111304 3 198 6.67E-72 T 28-03-2018 IPR023627 Recombination protein RecR MKLM6_RS19550 17df95233908fdf594ce5c95c5e97a43 198 Pfam PF13662 Toprim domain 81 171 3.6E-23 T 28-03-2018 IPR006171 TOPRIM domain MKLM6_RS19550 17df95233908fdf594ce5c95c5e97a43 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 98.756 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 MKLM6_RS19550 17df95233908fdf594ce5c95c5e97a43 198 SMART SM00493 80 165 3.5E-8 T 28-03-2018 IPR006171 TOPRIM domain MKLM6_RS19550 17df95233908fdf594ce5c95c5e97a43 198 Pfam PF02132 RecR protein 41 78 4.2E-12 T 28-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger MKLM6_RS18150 d278445ec62261d5521eff4417d75550 240 Gene3D G3DSA:3.40.30.10 2 97 2.0E-9 T 28-03-2018 MKLM6_RS18150 d278445ec62261d5521eff4417d75550 240 SUPERFAMILY SSF52833 2 101 3.22E-12 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS18150 d278445ec62261d5521eff4417d75550 240 Gene3D G3DSA:1.20.1050.10 98 228 5.7E-15 T 28-03-2018 MKLM6_RS18150 d278445ec62261d5521eff4417d75550 240 Pfam PF17171 Glutathione S-transferase, C-terminal domain 165 226 3.6E-12 T 28-03-2018 IPR033468 Metaxin, glutathione S-transferase domain MKLM6_RS18150 d278445ec62261d5521eff4417d75550 240 Pfam PF17172 Glutathione S-transferase N-terminal domain 19 115 1.2E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS18150 d278445ec62261d5521eff4417d75550 240 SUPERFAMILY SSF47616 157 227 4.49E-6 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like MKLM6_RS18150 d278445ec62261d5521eff4417d75550 240 SUPERFAMILY SSF47616 83 115 4.49E-6 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like MKLM6_RS14555 9c4052a46bc1929d506732f92afcba78 758 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 518 536 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 MKLM6_RS14555 9c4052a46bc1929d506732f92afcba78 758 SMART SM00382 206 352 7.0E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS14555 9c4052a46bc1929d506732f92afcba78 758 SMART SM00382 487 636 3.7E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS14555 9c4052a46bc1929d506732f92afcba78 758 SUPERFAMILY SSF52540 437 733 3.92E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS14555 9c4052a46bc1929d506732f92afcba78 758 Pfam PF07724 AAA domain (Cdc48 subfamily) 487 647 5.3E-48 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MKLM6_RS14555 9c4052a46bc1929d506732f92afcba78 758 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 211 324 3.6E-13 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MKLM6_RS14555 9c4052a46bc1929d506732f92afcba78 758 SUPERFAMILY SSF52540 168 421 4.88E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS14555 9c4052a46bc1929d506732f92afcba78 758 SMART SM01086 653 742 1.7E-32 T 28-03-2018 IPR019489 Clp ATPase, C-terminal MKLM6_RS14555 9c4052a46bc1929d506732f92afcba78 758 Gene3D G3DSA:1.10.8.60 653 756 7.6E-20 T 28-03-2018 MKLM6_RS14555 9c4052a46bc1929d506732f92afcba78 758 Gene3D G3DSA:1.10.1780.10 1 155 1.5E-21 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 MKLM6_RS14555 9c4052a46bc1929d506732f92afcba78 758 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 562 580 1.5E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 MKLM6_RS14555 9c4052a46bc1929d506732f92afcba78 758 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 595 609 1.5E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 MKLM6_RS14555 9c4052a46bc1929d506732f92afcba78 758 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 533 551 1.5E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 MKLM6_RS14555 9c4052a46bc1929d506732f92afcba78 758 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 491 509 1.5E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 MKLM6_RS14555 9c4052a46bc1929d506732f92afcba78 758 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 653 733 1.0E-21 T 28-03-2018 IPR019489 Clp ATPase, C-terminal MKLM6_RS14555 9c4052a46bc1929d506732f92afcba78 758 Gene3D G3DSA:1.10.8.60 351 450 5.0E-28 T 28-03-2018 MKLM6_RS14555 9c4052a46bc1929d506732f92afcba78 758 Gene3D G3DSA:3.40.50.300 165 350 4.4E-27 T 28-03-2018 MKLM6_RS14555 9c4052a46bc1929d506732f92afcba78 758 SUPERFAMILY SSF81923 1 141 1.96E-55 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 MKLM6_RS14555 9c4052a46bc1929d506732f92afcba78 758 Gene3D G3DSA:3.40.50.300 451 652 3.3E-43 T 28-03-2018 MKLM6_RS14555 9c4052a46bc1929d506732f92afcba78 758 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 302 314 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 MKLM6_RS14555 9c4052a46bc1929d506732f92afcba78 758 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 62 1.7E-9 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 MKLM6_RS14555 9c4052a46bc1929d506732f92afcba78 758 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 734 0.0 T 28-03-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0004176 MKLM6_RS17415 0a9b887b0754a0c5c90c093e1980aea1 178 Gene3D G3DSA:3.30.70.1290 1 149 1.5E-22 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS17415 0a9b887b0754a0c5c90c093e1980aea1 178 SUPERFAMILY SSF143422 5 149 5.62E-21 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS17415 0a9b887b0754a0c5c90c093e1980aea1 178 SMART SM01321 10 143 1.0E-6 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS02950 f87ee39892d98f59be6e284af74bad29 669 Gene3D G3DSA:3.40.50.970 1 370 9.0E-122 T 28-03-2018 MKLM6_RS02950 f87ee39892d98f59be6e284af74bad29 669 ProSitePatterns PS00802 Transketolase signature 2. 474 490 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MKLM6_RS02950 f87ee39892d98f59be6e284af74bad29 669 Pfam PF02780 Transketolase, C-terminal domain 553 661 4.3E-15 T 28-03-2018 IPR033248 Transketolase, C-terminal domain MKLM6_RS02950 f87ee39892d98f59be6e284af74bad29 669 SUPERFAMILY SSF52518 6 335 1.18E-116 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS02950 f87ee39892d98f59be6e284af74bad29 669 Gene3D G3DSA:3.40.50.970 371 547 5.3E-39 T 28-03-2018 MKLM6_RS02950 f87ee39892d98f59be6e284af74bad29 669 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 4 340 2.0E-164 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MKLM6_RS02950 f87ee39892d98f59be6e284af74bad29 669 SUPERFAMILY SSF52518 351 532 1.79E-67 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS02950 f87ee39892d98f59be6e284af74bad29 669 SMART SM00861 361 532 1.6E-66 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MKLM6_RS02950 f87ee39892d98f59be6e284af74bad29 669 ProSitePatterns PS00801 Transketolase signature 1. 12 32 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MKLM6_RS02950 f87ee39892d98f59be6e284af74bad29 669 Gene3D G3DSA:3.40.50.920 548 668 6.7E-33 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MKLM6_RS02950 f87ee39892d98f59be6e284af74bad29 669 Pfam PF02779 Transketolase, pyrimidine binding domain 360 532 1.2E-45 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MKLM6_RS02950 f87ee39892d98f59be6e284af74bad29 669 SUPERFAMILY SSF52922 540 669 3.53E-43 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MKLM6_RS02950 f87ee39892d98f59be6e284af74bad29 669 TIGRFAM TIGR00232 tktlase_bact: transketolase 6 668 0.0 T 28-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 MKLM6_RS16800 afe5dcd0cb29387a7267e10c063c0cb9 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.1E-35 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MKLM6_RS16800 afe5dcd0cb29387a7267e10c063c0cb9 90 SMART SM00411 1 90 8.3E-45 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MKLM6_RS16800 afe5dcd0cb29387a7267e10c063c0cb9 90 SUPERFAMILY SSF47729 1 90 7.51E-33 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 MKLM6_RS16800 afe5dcd0cb29387a7267e10c063c0cb9 90 Gene3D G3DSA:4.10.520.10 1 90 9.4E-37 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 MKLM6_RS16800 afe5dcd0cb29387a7267e10c063c0cb9 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 3.0E-20 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MKLM6_RS16800 afe5dcd0cb29387a7267e10c063c0cb9 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 3.0E-20 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MKLM6_RS16800 afe5dcd0cb29387a7267e10c063c0cb9 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 3.0E-20 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MKLM6_RS16800 afe5dcd0cb29387a7267e10c063c0cb9 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 MKLM6_RS02490 4a212a1efc8848a81e5ed260faa21901 147 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 103 7.7E-6 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily MKLM6_RS02490 4a212a1efc8848a81e5ed260faa21901 147 SMART SM00226 3 141 1.4E-4 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily MKLM6_RS02490 4a212a1efc8848a81e5ed260faa21901 147 Gene3D G3DSA:3.40.50.2300 2 145 2.1E-19 T 28-03-2018 MKLM6_RS02490 4a212a1efc8848a81e5ed260faa21901 147 SUPERFAMILY SSF52788 2 142 2.09E-19 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily MKLM6_RS08370 da3a3bbc6fdd0d0761473855ed05573e 187 Gene3D G3DSA:1.10.490.10 2 161 2.4E-22 T 28-03-2018 MKLM6_RS08370 da3a3bbc6fdd0d0761473855ed05573e 187 SUPERFAMILY SSF46458 18 141 5.14E-18 T 28-03-2018 IPR009050 Globin-like MKLM6_RS08370 da3a3bbc6fdd0d0761473855ed05573e 187 Pfam PF11563 Protoglobin 10 157 2.2E-22 T 28-03-2018 MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 SUPERFAMILY SSF55785 247 366 2.44E-22 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 SMART SM00267 368 540 1.6E-66 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 Gene3D G3DSA:3.30.450.20 253 365 3.6E-22 T 28-03-2018 MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 SUPERFAMILY SSF141868 556 804 1.7E-87 T 28-03-2018 IPR001633 EAL domain MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 SMART SM00086 326 368 16.0 T 28-03-2018 IPR001610 PAC motif MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 SMART SM00086 92 131 130.0 T 28-03-2018 IPR001610 PAC motif MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 SMART SM00086 210 250 13.0 T 28-03-2018 IPR001610 PAC motif MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 Gene3D G3DSA:3.30.70.270 380 548 1.9E-60 T 28-03-2018 MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 SMART SM00091 258 324 1.1E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 SMART SM00091 139 204 2.1 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 SMART SM00091 16 84 0.36 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 262 372 3.4E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 145 257 8.3E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 12 138 2.0E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 Pfam PF12860 PAS fold 22 134 7.1E-9 T 28-03-2018 MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 Gene3D G3DSA:3.20.20.450 549 807 6.8E-97 T 28-03-2018 IPR001633 EAL domain MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 377 537 1.4E-45 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 Pfam PF00990 Diguanylate cyclase, GGDEF domain 379 536 3.1E-51 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 Gene3D G3DSA:3.30.450.20 1 138 2.4E-19 T 28-03-2018 MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 SMART SM00052 550 797 1.2E-105 T 28-03-2018 IPR001633 EAL domain MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 SUPERFAMILY SSF55073 384 540 2.35E-49 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 SUPERFAMILY SSF55785 9 129 8.55E-12 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 Pfam PF13426 PAS domain 269 367 4.8E-13 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 Pfam PF13426 PAS domain 152 249 1.4E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 SUPERFAMILY SSF55785 153 259 1.29E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 Pfam PF00563 EAL domain 556 792 5.3E-71 T 28-03-2018 IPR001633 EAL domain MKLM6_RS18930 0c31d93255b948506ab599217b9ce310 807 Gene3D G3DSA:3.30.450.20 139 252 3.0E-18 T 28-03-2018 MKLM6_RS04930 c483182bd3dff37b27e0726ecdec3011 156 Gene3D G3DSA:2.60.40.790 19 138 3.3E-22 T 28-03-2018 IPR008978 HSP20-like chaperone MKLM6_RS04930 c483182bd3dff37b27e0726ecdec3011 156 Pfam PF00011 Hsp20/alpha crystallin family 44 137 2.2E-19 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain MKLM6_RS04930 c483182bd3dff37b27e0726ecdec3011 156 SUPERFAMILY SSF49764 32 138 1.33E-21 T 28-03-2018 IPR008978 HSP20-like chaperone MKLM6_RS13665 b38db0de30b747b66c79e66c031545dd 76 SUPERFAMILY SSF64307 2 75 6.28E-20 T 28-03-2018 IPR001455 TusA-like domain MKLM6_RS13665 b38db0de30b747b66c79e66c031545dd 76 Pfam PF01206 Sulfurtransferase TusA 7 75 2.1E-16 T 28-03-2018 IPR001455 TusA-like domain MKLM6_RS13665 b38db0de30b747b66c79e66c031545dd 76 Gene3D G3DSA:3.30.110.40 2 76 3.8E-20 T 28-03-2018 IPR001455 TusA-like domain MKLM6_RS13665 b38db0de30b747b66c79e66c031545dd 76 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 8 32 - T 28-03-2018 IPR001455 TusA-like domain MKLM6_RS12940 a644ea2bdf9075e41328cd285d146258 406 Gene3D G3DSA:3.90.1150.10 283 401 8.9E-40 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS12940 a644ea2bdf9075e41328cd285d146258 406 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 7 405 7.1E-185 T 28-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 MKLM6_RS12940 a644ea2bdf9075e41328cd285d146258 406 PIRSF PIRSF005572 22 405 3.6E-51 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 MKLM6_RS12940 a644ea2bdf9075e41328cd285d146258 406 Pfam PF00266 Aminotransferase class-V 25 394 1.3E-151 T 28-03-2018 IPR000192 Aminotransferase class V domain MKLM6_RS12940 a644ea2bdf9075e41328cd285d146258 406 Gene3D G3DSA:3.40.640.10 34 282 5.6E-58 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS12940 a644ea2bdf9075e41328cd285d146258 406 SUPERFAMILY SSF53383 4 402 4.73E-125 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS12940 a644ea2bdf9075e41328cd285d146258 406 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 217 236 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MKLM6_RS05840 e95ee25121541795b9ff879e34d40111 184 SUPERFAMILY SSF55729 36 179 2.66E-32 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS05840 e95ee25121541795b9ff879e34d40111 184 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 44 175 1.7E-38 T 28-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 MKLM6_RS05840 e95ee25121541795b9ff879e34d40111 184 Pfam PF00583 Acetyltransferase (GNAT) family 63 154 3.5E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 MKLM6_RS05840 e95ee25121541795b9ff879e34d40111 184 Gene3D G3DSA:3.40.630.30 34 182 5.2E-32 T 28-03-2018 MKLM6_RS18575 cbe1cd602230eb79cabf7e1653d59873 361 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 357 1.1E-170 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 MKLM6_RS18575 cbe1cd602230eb79cabf7e1653d59873 361 Pfam PF00472 RF-1 domain 215 323 2.3E-41 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MKLM6_RS18575 cbe1cd602230eb79cabf7e1653d59873 361 SUPERFAMILY SSF75620 12 355 2.22E-136 T 28-03-2018 MKLM6_RS18575 cbe1cd602230eb79cabf7e1653d59873 361 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 359 41.391 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 MKLM6_RS18575 cbe1cd602230eb79cabf7e1653d59873 361 SMART SM00937 67 180 1.2E-66 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 MKLM6_RS18575 cbe1cd602230eb79cabf7e1653d59873 361 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 230 246 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MKLM6_RS18575 cbe1cd602230eb79cabf7e1653d59873 361 Pfam PF03462 PCRF domain 14 205 1.9E-75 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 MKLM6_RS18575 cbe1cd602230eb79cabf7e1653d59873 361 Gene3D G3DSA:3.30.160.20 211 293 1.4E-33 T 28-03-2018 MKLM6_RS18575 cbe1cd602230eb79cabf7e1653d59873 361 Gene3D G3DSA:1.20.58.410 3 103 1.9E-18 T 28-03-2018 MKLM6_RS15700 588ffd325ee1d433c1d6025ba1e8a66e 119 Gene3D G3DSA:3.40.250.10 2 119 2.7E-28 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS15700 588ffd325ee1d433c1d6025ba1e8a66e 119 ProSitePatterns PS00380 Rhodanese signature 1. 42 53 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 MKLM6_RS15700 588ffd325ee1d433c1d6025ba1e8a66e 119 SUPERFAMILY SSF52821 6 118 2.88E-31 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS15700 588ffd325ee1d433c1d6025ba1e8a66e 119 SMART SM00450 17 117 1.2E-20 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS15700 588ffd325ee1d433c1d6025ba1e8a66e 119 Pfam PF00581 Rhodanese-like domain 30 113 1.6E-16 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS19590 4a7c00844bc6333320b250f39cd14fc9 294 SUPERFAMILY SSF56317 3 290 2.88E-84 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS19590 4a7c00844bc6333320b250f39cd14fc9 294 Pfam PF00795 Carbon-nitrogen hydrolase 10 272 1.2E-54 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS19590 4a7c00844bc6333320b250f39cd14fc9 294 Gene3D G3DSA:3.60.110.10 5 287 2.4E-78 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS17310 6725e2183223dc5fd5e102b706bb253d 244 Gene3D G3DSA:3.90.550.10 4 240 3.5E-25 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS17310 6725e2183223dc5fd5e102b706bb253d 244 SUPERFAMILY SSF53448 5 238 2.63E-29 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS17310 6725e2183223dc5fd5e102b706bb253d 244 Pfam PF00535 Glycosyl transferase family 2 5 139 5.6E-16 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MKLM6_RS02415 9d54a23e9c1d2712df33f91cf54c3675 386 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 76 302 6.4E-48 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MKLM6_RS02415 9d54a23e9c1d2712df33f91cf54c3675 386 Gene3D G3DSA:2.40.50.100 85 134 7.3E-7 T 28-03-2018 MKLM6_RS02415 9d54a23e9c1d2712df33f91cf54c3675 386 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 85 381 4.3E-63 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MKLM6_RS02415 9d54a23e9c1d2712df33f91cf54c3675 386 SUPERFAMILY SSF111369 86 307 3.01E-30 T 28-03-2018 MKLM6_RS02415 9d54a23e9c1d2712df33f91cf54c3675 386 Gene3D G3DSA:1.20.1600.10 135 307 1.3E-30 T 28-03-2018 MKLM6_RS06580 72eac229353816a959fc64e9539a2f2a 472 Gene3D G3DSA:2.120.10.30 34 424 2.2E-15 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MKLM6_RS06580 72eac229353816a959fc64e9539a2f2a 472 Pfam PF13449 Esterase-like activity of phytase 46 369 1.3E-67 T 28-03-2018 IPR027372 Phytase-like domain MKLM6_RS06580 72eac229353816a959fc64e9539a2f2a 472 SUPERFAMILY SSF75011 338 370 2.09E-14 T 28-03-2018 MKLM6_RS06580 72eac229353816a959fc64e9539a2f2a 472 SUPERFAMILY SSF75011 124 309 2.09E-14 T 28-03-2018 MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 SMART SM00387 598 698 1.7E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 Gene3D G3DSA:3.30.450.20 118 234 1.7E-24 T 28-03-2018 MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 SMART SM00086 199 239 1.2 T 28-03-2018 IPR001610 PAC motif MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 SMART SM00086 78 118 4.7 T 28-03-2018 IPR001610 PAC motif MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 SMART SM00086 319 361 3.8E-4 T 28-03-2018 IPR001610 PAC motif MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 SMART SM00086 442 482 0.094 T 28-03-2018 IPR001610 PAC motif MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 245 367 1.1E-29 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 363 488 5.1E-28 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 122 245 3.6E-26 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 4 124 6.5E-23 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 Pfam PF00989 PAS fold 248 356 1.8E-20 T 28-03-2018 IPR013767 PAS fold GO:0006355 MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 Pfam PF00989 PAS fold 124 236 5.7E-15 T 28-03-2018 IPR013767 PAS fold GO:0006355 MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 Pfam PF07568 Histidine kinase 502 577 1.0E-26 T 28-03-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 SUPERFAMILY SSF55874 564 693 5.5E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 SMART SM00091 247 313 1.3E-13 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 SMART SM00091 123 189 2.6E-11 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 SMART SM00091 2 68 1.4E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 SMART SM00091 366 432 6.8E-11 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 Gene3D G3DSA:3.30.565.10 554 704 1.3E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 SUPERFAMILY SSF55785 134 245 2.65E-27 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 Pfam PF13426 PAS domain 12 117 7.1E-15 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 Pfam PF13426 PAS domain 376 481 5.1E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 SUPERFAMILY SSF55785 377 489 1.68E-28 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 Gene3D G3DSA:3.30.450.20 236 363 1.0E-30 T 28-03-2018 MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 Gene3D G3DSA:3.30.450.20 364 523 6.7E-26 T 28-03-2018 MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 Gene3D G3DSA:3.30.450.20 2 117 9.3E-21 T 28-03-2018 MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 SUPERFAMILY SSF55785 13 126 8.52E-26 T 28-03-2018 IPR000014 PAS domain MKLM6_RS07895 7d64047655096263a6568426dda0c766 704 SUPERFAMILY SSF55785 238 359 8.55E-27 T 28-03-2018 IPR000014 PAS domain MKLM6_RS00075 0127117e1a33e3b764c45820645887a1 158 SMART SM00347 27 127 8.5E-27 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MKLM6_RS00075 0127117e1a33e3b764c45820645887a1 158 Gene3D G3DSA:1.10.10.10 5 127 1.8E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS00075 0127117e1a33e3b764c45820645887a1 158 ProSitePatterns PS01117 MarR-type HTH domain signature. 66 100 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MKLM6_RS00075 0127117e1a33e3b764c45820645887a1 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 1.5E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MKLM6_RS00075 0127117e1a33e3b764c45820645887a1 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 1.5E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MKLM6_RS00075 0127117e1a33e3b764c45820645887a1 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 1.5E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MKLM6_RS00075 0127117e1a33e3b764c45820645887a1 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 1.5E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MKLM6_RS00075 0127117e1a33e3b764c45820645887a1 158 SUPERFAMILY SSF46785 9 142 1.09E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS00075 0127117e1a33e3b764c45820645887a1 158 Pfam PF01047 MarR family 34 91 4.4E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MKLM6_RS05865 2eb4df68d29eb16c2797556ae2bb84ff 239 Hamap MF_00689 Putative arginyl-tRNA--protein transferase [ate]. 1 232 40.66 T 28-03-2018 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic MetaCyc: PWY-7799 MKLM6_RS05865 2eb4df68d29eb16c2797556ae2bb84ff 239 Gene3D G3DSA:3.40.630.30 72 215 4.2E-9 T 28-03-2018 MKLM6_RS05865 2eb4df68d29eb16c2797556ae2bb84ff 239 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 103 220 2.7E-38 T 28-03-2018 IPR007472 Arginine-tRNA-protein transferase, C-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7799 MKLM6_RS05865 2eb4df68d29eb16c2797556ae2bb84ff 239 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 13 82 1.9E-20 T 28-03-2018 IPR007471 Arginine-tRNA-protein transferase, N-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7799 MKLM6_RS05865 2eb4df68d29eb16c2797556ae2bb84ff 239 SUPERFAMILY SSF55729 76 234 6.22E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS05865 2eb4df68d29eb16c2797556ae2bb84ff 239 PIRSF PIRSF037208 2 239 4.2E-83 T 28-03-2018 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic MetaCyc: PWY-7799 MKLM6_RS07950 bbc25fb0aba80a6dfdd040c7199c0818 450 TIGRFAM TIGR00937 2A51: chromate efflux transporter 22 439 1.9E-69 T 28-03-2018 IPR014047 Chromate transporter, long chain MKLM6_RS07950 bbc25fb0aba80a6dfdd040c7199c0818 450 PIRSF PIRSF004810 2 446 3.0E-126 T 28-03-2018 IPR014047 Chromate transporter, long chain MKLM6_RS07950 bbc25fb0aba80a6dfdd040c7199c0818 450 Pfam PF02417 Chromate transporter 255 440 1.5E-33 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 MKLM6_RS07950 bbc25fb0aba80a6dfdd040c7199c0818 450 Pfam PF02417 Chromate transporter 18 179 3.7E-35 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 MKLM6_RS10375 9affe61c23faf1128c815db735344572 536 Gene3D G3DSA:3.40.190.10 235 426 4.0E-10 T 28-03-2018 MKLM6_RS20215 002381a3f56b58dd0fe21aa5824ec844 491 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 350 481 4.4E-13 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain MKLM6_RS03040 dd097cfc883942c1b6a125a831434cdf 453 Gene3D G3DSA:3.40.640.10 208 332 5.8E-38 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS03040 dd097cfc883942c1b6a125a831434cdf 453 PIRSF PIRSF000521 19 442 1.5E-26 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MKLM6_RS03040 dd097cfc883942c1b6a125a831434cdf 453 Gene3D G3DSA:3.90.1150.10 333 453 1.3E-28 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS03040 dd097cfc883942c1b6a125a831434cdf 453 SUPERFAMILY SSF53383 12 445 3.42E-130 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS03040 dd097cfc883942c1b6a125a831434cdf 453 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 5 450 49.437 T 28-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 MKLM6_RS03040 dd097cfc883942c1b6a125a831434cdf 453 Gene3D G3DSA:3.90.1150.10 3 207 5.8E-48 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS03040 dd097cfc883942c1b6a125a831434cdf 453 Pfam PF00202 Aminotransferase class-III 28 442 1.0E-123 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MKLM6_RS03040 dd097cfc883942c1b6a125a831434cdf 453 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 17 444 9.4E-172 T 28-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 MKLM6_RS03040 dd097cfc883942c1b6a125a831434cdf 453 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 255 292 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MKLM6_RS04060 51beff130e05e6e9453a660ad8aa1d11 530 Pfam PF13091 PLD-like domain 372 522 6.6E-15 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MKLM6_RS04060 51beff130e05e6e9453a660ad8aa1d11 530 Pfam PF13091 PLD-like domain 218 332 2.1E-13 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MKLM6_RS04060 51beff130e05e6e9453a660ad8aa1d11 530 SMART SM00155 279 306 0.099 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MKLM6_RS04060 51beff130e05e6e9453a660ad8aa1d11 530 SMART SM00155 469 496 48.0 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MKLM6_RS04060 51beff130e05e6e9453a660ad8aa1d11 530 SUPERFAMILY SSF56024 369 522 1.7E-18 T 28-03-2018 MKLM6_RS04060 51beff130e05e6e9453a660ad8aa1d11 530 Gene3D G3DSA:3.30.870.10 354 525 1.6E-15 T 28-03-2018 MKLM6_RS04060 51beff130e05e6e9453a660ad8aa1d11 530 Gene3D G3DSA:3.30.870.10 179 335 1.4E-15 T 28-03-2018 MKLM6_RS04060 51beff130e05e6e9453a660ad8aa1d11 530 SUPERFAMILY SSF56024 211 332 4.26E-17 T 28-03-2018 MKLM6_RS17020 493041cbcc1e9cdbf63465f86fc36bac 95 Gene3D G3DSA:3.10.20.30 1 94 1.6E-19 T 28-03-2018 IPR012675 Beta-grasp domain MKLM6_RS17020 493041cbcc1e9cdbf63465f86fc36bac 95 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 85 1.2E-14 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MKLM6_RS17020 493041cbcc1e9cdbf63465f86fc36bac 95 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MKLM6_RS17020 493041cbcc1e9cdbf63465f86fc36bac 95 SUPERFAMILY SSF54292 3 88 8.52E-21 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MKLM6_RS14135 80775a6b9ed3e619492e8e713a794ce1 485 Gene3D G3DSA:1.10.45.10 418 456 8.8E-13 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 MKLM6_RS14135 80775a6b9ed3e619492e8e713a794ce1 485 Gene3D G3DSA:3.30.43.10 3 93 2.0E-22 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 MKLM6_RS14135 80775a6b9ed3e619492e8e713a794ce1 485 Pfam PF01565 FAD binding domain 42 180 9.8E-40 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MKLM6_RS14135 80775a6b9ed3e619492e8e713a794ce1 485 SUPERFAMILY SSF55103 220 469 5.89E-72 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MKLM6_RS14135 80775a6b9ed3e619492e8e713a794ce1 485 SUPERFAMILY SSF56176 12 217 7.01E-67 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MKLM6_RS14135 80775a6b9ed3e619492e8e713a794ce1 485 Pfam PF02913 FAD linked oxidases, C-terminal domain 217 456 1.1E-68 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 MKLM6_RS14135 80775a6b9ed3e619492e8e713a794ce1 485 Gene3D G3DSA:3.30.465.10 94 239 4.7E-40 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MKLM6_RS09170 1d32b07040dac6fcb7847ef3809ceb56 334 Pfam PF13379 NMT1-like family 36 261 3.2E-19 T 28-03-2018 MKLM6_RS09170 1d32b07040dac6fcb7847ef3809ceb56 334 SUPERFAMILY SSF53850 40 258 8.61E-32 T 28-03-2018 MKLM6_RS09170 1d32b07040dac6fcb7847ef3809ceb56 334 Gene3D G3DSA:3.40.190.10 36 136 4.0E-6 T 28-03-2018 MKLM6_RS09170 1d32b07040dac6fcb7847ef3809ceb56 334 Gene3D G3DSA:3.40.190.10 137 333 1.4E-29 T 28-03-2018 MKLM6_RS12105 8db088c8883bbc4f16545367dd7f3f2d 88 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 26 78 1.5E-13 T 28-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MKLM6_RS12105 8db088c8883bbc4f16545367dd7f3f2d 88 Hamap MF_01396 ATP synthase subunit c [atpH]. 12 77 13.759 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12105 8db088c8883bbc4f16545367dd7f3f2d 88 SUPERFAMILY SSF81333 14 81 2.75E-18 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 MKLM6_RS12105 8db088c8883bbc4f16545367dd7f3f2d 88 PRINTS PR00124 ATP synthase C subunit signature 35 50 5.2E-14 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12105 8db088c8883bbc4f16545367dd7f3f2d 88 PRINTS PR00124 ATP synthase C subunit signature 52 77 5.2E-14 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12105 8db088c8883bbc4f16545367dd7f3f2d 88 PRINTS PR00124 ATP synthase C subunit signature 14 33 5.2E-14 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12105 8db088c8883bbc4f16545367dd7f3f2d 88 Gene3D G3DSA:1.20.20.10 4 80 1.2E-17 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 MKLM6_RS12105 8db088c8883bbc4f16545367dd7f3f2d 88 ProSitePatterns PS00605 ATP synthase c subunit signature. 42 63 - T 28-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12105 8db088c8883bbc4f16545367dd7f3f2d 88 Pfam PF00137 ATP synthase subunit C 15 75 9.5E-15 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 MKLM6_RS21730 b2d962bfbb1996549819d0cc79f1af11 399 Pfam PF03235 Protein of unknown function DUF262 68 204 5.2E-25 T 28-03-2018 IPR004919 Domain of unknown function DUF262 MKLM6_RS08660 5c85bef20b9bd80b5ccf3d115b33bb1f 328 SUPERFAMILY SSF102114 15 321 3.27E-89 T 28-03-2018 MKLM6_RS08660 5c85bef20b9bd80b5ccf3d115b33bb1f 328 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 230 320 3.1E-20 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MKLM6_RS08660 5c85bef20b9bd80b5ccf3d115b33bb1f 328 Pfam PF04055 Radical SAM superfamily 60 213 5.9E-15 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS08660 5c85bef20b9bd80b5ccf3d115b33bb1f 328 SMART SM00876 230 322 4.6E-44 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MKLM6_RS08660 5c85bef20b9bd80b5ccf3d115b33bb1f 328 Gene3D G3DSA:3.20.20.70 14 324 1.9E-55 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS08660 5c85bef20b9bd80b5ccf3d115b33bb1f 328 PIRSF PIRSF001619 2 327 3.6E-133 T 28-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MKLM6_RS08660 5c85bef20b9bd80b5ccf3d115b33bb1f 328 Hamap MF_01694 Biotin synthase [bioB]. 15 323 41.907 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MKLM6_RS08660 5c85bef20b9bd80b5ccf3d115b33bb1f 328 SMART SM00729 53 265 7.2E-38 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MKLM6_RS08660 5c85bef20b9bd80b5ccf3d115b33bb1f 328 TIGRFAM TIGR00433 bioB: biotin synthase 25 320 2.9E-124 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MKLM6_RS02420 7534ba1a616542cdfa8fcbd1f544c52b 1022 Gene3D G3DSA:1.20.1640.10 802 1018 1.1E-43 T 28-03-2018 MKLM6_RS02420 7534ba1a616542cdfa8fcbd1f544c52b 1022 SUPERFAMILY SSF82866 289 494 3.53E-35 T 28-03-2018 MKLM6_RS02420 7534ba1a616542cdfa8fcbd1f544c52b 1022 SUPERFAMILY SSF82866 794 1017 7.59E-56 T 28-03-2018 MKLM6_RS02420 7534ba1a616542cdfa8fcbd1f544c52b 1022 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1018 0.0 T 28-03-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 MKLM6_RS02420 7534ba1a616542cdfa8fcbd1f544c52b 1022 SUPERFAMILY SSF82714 712 796 2.49E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS02420 7534ba1a616542cdfa8fcbd1f544c52b 1022 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 1.2E-23 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS02420 7534ba1a616542cdfa8fcbd1f544c52b 1022 PRINTS PR00702 Acriflavin resistance protein family signature 443 466 1.2E-23 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS02420 7534ba1a616542cdfa8fcbd1f544c52b 1022 PRINTS PR00702 Acriflavin resistance protein family signature 541 558 1.2E-23 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS02420 7534ba1a616542cdfa8fcbd1f544c52b 1022 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 1.2E-23 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS02420 7534ba1a616542cdfa8fcbd1f544c52b 1022 PRINTS PR00702 Acriflavin resistance protein family signature 468 491 1.2E-23 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS02420 7534ba1a616542cdfa8fcbd1f544c52b 1022 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 1.2E-23 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS02420 7534ba1a616542cdfa8fcbd1f544c52b 1022 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 1.2E-23 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS02420 7534ba1a616542cdfa8fcbd1f544c52b 1022 SUPERFAMILY SSF82693 137 180 6.28E-15 T 28-03-2018 MKLM6_RS02420 7534ba1a616542cdfa8fcbd1f544c52b 1022 SUPERFAMILY SSF82693 266 324 6.28E-15 T 28-03-2018 MKLM6_RS02420 7534ba1a616542cdfa8fcbd1f544c52b 1022 Gene3D G3DSA:3.30.2090.10 711 798 4.5E-20 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS02420 7534ba1a616542cdfa8fcbd1f544c52b 1022 SUPERFAMILY SSF82693 44 126 1.46E-18 T 28-03-2018 MKLM6_RS02420 7534ba1a616542cdfa8fcbd1f544c52b 1022 Pfam PF00873 AcrB/AcrD/AcrF family 6 1016 3.6E-275 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS02420 7534ba1a616542cdfa8fcbd1f544c52b 1022 Gene3D G3DSA:3.30.70.1430 556 655 3.0E-10 T 28-03-2018 MKLM6_RS02420 7534ba1a616542cdfa8fcbd1f544c52b 1022 SUPERFAMILY SSF82714 182 264 3.4E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS02420 7534ba1a616542cdfa8fcbd1f544c52b 1022 Gene3D G3DSA:3.30.70.1430 42 137 6.5E-17 T 28-03-2018 MKLM6_RS02420 7534ba1a616542cdfa8fcbd1f544c52b 1022 Gene3D G3DSA:1.20.1640.10 287 506 4.9E-38 T 28-03-2018 MKLM6_RS02420 7534ba1a616542cdfa8fcbd1f544c52b 1022 Gene3D G3DSA:3.30.2090.10 179 266 5.2E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS14760 7029f7dd041ffee77cd68836218bcf70 118 Pfam PF07238 PilZ domain 3 96 3.4E-6 T 28-03-2018 IPR009875 PilZ domain GO:0035438 MKLM6_RS14760 7029f7dd041ffee77cd68836218bcf70 118 SUPERFAMILY SSF141371 1 93 1.67E-6 T 28-03-2018 MKLM6_RS14760 7029f7dd041ffee77cd68836218bcf70 118 Gene3D G3DSA:2.40.10.220 1 109 1.7E-10 T 28-03-2018 MKLM6_RS18590 1d89239011359b1ceaf21c35aa141512 462 Gene3D G3DSA:3.40.50.2300 2 127 3.0E-23 T 28-03-2018 MKLM6_RS18590 1d89239011359b1ceaf21c35aa141512 462 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 359 368 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site MKLM6_RS18590 1d89239011359b1ceaf21c35aa141512 462 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 170 183 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MKLM6_RS18590 1d89239011359b1ceaf21c35aa141512 462 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 232 247 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MKLM6_RS18590 1d89239011359b1ceaf21c35aa141512 462 SMART SM00382 166 309 3.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS18590 1d89239011359b1ceaf21c35aa141512 462 Pfam PF00072 Response regulator receiver domain 6 114 6.2E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS18590 1d89239011359b1ceaf21c35aa141512 462 Pfam PF02954 Bacterial regulatory protein, Fis family 415 455 2.1E-12 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS18590 1d89239011359b1ceaf21c35aa141512 462 Gene3D G3DSA:1.10.10.60 420 459 1.7E-13 T 28-03-2018 MKLM6_RS18590 1d89239011359b1ceaf21c35aa141512 462 Gene3D G3DSA:1.10.8.60 318 419 2.2E-22 T 28-03-2018 MKLM6_RS18590 1d89239011359b1ceaf21c35aa141512 462 SUPERFAMILY SSF52540 145 381 5.41E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS18590 1d89239011359b1ceaf21c35aa141512 462 SMART SM00448 3 116 5.5E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS18590 1d89239011359b1ceaf21c35aa141512 462 SUPERFAMILY SSF46689 359 457 2.42E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS18590 1d89239011359b1ceaf21c35aa141512 462 Gene3D G3DSA:3.40.50.300 128 317 1.4E-25 T 28-03-2018 MKLM6_RS18590 1d89239011359b1ceaf21c35aa141512 462 Pfam PF00158 Sigma-54 interaction domain 145 312 1.8E-60 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MKLM6_RS18590 1d89239011359b1ceaf21c35aa141512 462 SUPERFAMILY SSF52172 4 189 4.27E-29 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS18590 1d89239011359b1ceaf21c35aa141512 462 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 421 438 1.7E-9 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS18590 1d89239011359b1ceaf21c35aa141512 462 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 438 458 1.7E-9 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS14420 79825faf183ae387b730bc6ebe2496f5 283 SUPERFAMILY SSF53335 13 272 1.67E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS14420 79825faf183ae387b730bc6ebe2496f5 283 Gene3D G3DSA:3.40.50.150 3 266 1.2E-44 T 28-03-2018 MKLM6_RS14420 79825faf183ae387b730bc6ebe2496f5 283 Pfam PF01209 ubiE/COQ5 methyltransferase family 11 149 9.8E-22 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MKLM6_RS02185 ee458bfc42003de1335f81b01edc6d9b 225 Pfam PF13419 Haloacid dehalogenase-like hydrolase 12 184 7.0E-13 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS02185 ee458bfc42003de1335f81b01edc6d9b 225 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 86 184 1.1E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MKLM6_RS02185 ee458bfc42003de1335f81b01edc6d9b 225 SUPERFAMILY SSF56784 2 213 5.35E-36 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS02185 ee458bfc42003de1335f81b01edc6d9b 225 Gene3D G3DSA:3.40.50.1000 2 218 6.1E-23 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS18320 a7e794b032194f59e89a4330e532f58d 206 ProSitePatterns PS00632 Ribosomal protein S4 signature. 94 118 - T 28-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18320 a7e794b032194f59e89a4330e532f58d 206 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 95 9.3E-29 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 MKLM6_RS18320 a7e794b032194f59e89a4330e532f58d 206 SMART SM00363 96 160 3.5E-17 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MKLM6_RS18320 a7e794b032194f59e89a4330e532f58d 206 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 206 4.7E-78 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 MKLM6_RS18320 a7e794b032194f59e89a4330e532f58d 206 SMART SM01390 3 95 1.1E-44 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 MKLM6_RS18320 a7e794b032194f59e89a4330e532f58d 206 Gene3D G3DSA:1.10.1050.10 1 101 2.7E-40 T 28-03-2018 MKLM6_RS18320 a7e794b032194f59e89a4330e532f58d 206 Gene3D G3DSA:1.10.1050.10 144 206 7.2E-16 T 28-03-2018 MKLM6_RS18320 a7e794b032194f59e89a4330e532f58d 206 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 206 34.34 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 MKLM6_RS18320 a7e794b032194f59e89a4330e532f58d 206 SUPERFAMILY SSF55174 3 206 3.93E-67 T 28-03-2018 MKLM6_RS18320 a7e794b032194f59e89a4330e532f58d 206 Pfam PF01479 S4 domain 97 143 8.9E-18 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MKLM6_RS18320 a7e794b032194f59e89a4330e532f58d 206 Gene3D G3DSA:3.10.290.10 102 143 1.4E-15 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MKLM6_RS08430 644d755bd945540e505915c7cdb43ffd 265 SUPERFAMILY SSF74653 182 262 3.4E-24 T 28-03-2018 MKLM6_RS08430 644d755bd945540e505915c7cdb43ffd 265 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 188 264 3.1E-21 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 MKLM6_RS08430 644d755bd945540e505915c7cdb43ffd 265 Gene3D G3DSA:3.30.1150.10 127 265 4.3E-24 T 28-03-2018 MKLM6_RS08430 644d755bd945540e505915c7cdb43ffd 265 PRINTS PR01374 Gram-negative bacterial tonB protein signature 203 221 7.2E-8 T 28-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 MKLM6_RS08430 644d755bd945540e505915c7cdb43ffd 265 PRINTS PR01374 Gram-negative bacterial tonB protein signature 120 130 7.2E-8 T 28-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 MKLM6_RS08430 644d755bd945540e505915c7cdb43ffd 265 PRINTS PR01374 Gram-negative bacterial tonB protein signature 182 203 7.2E-8 T 28-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 MKLM6_RS08430 644d755bd945540e505915c7cdb43ffd 265 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 186 264 3.3E-23 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 MKLM6_RS04870 8fd98e590e12000de7baee4b6fb2f32a 115 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 31.399 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS04870 8fd98e590e12000de7baee4b6fb2f32a 115 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 28-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS04870 8fd98e590e12000de7baee4b6fb2f32a 115 PIRSF PIRSF002191 1 115 1.2E-49 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS04870 8fd98e590e12000de7baee4b6fb2f32a 115 Pfam PF01245 Ribosomal protein L19 4 113 1.2E-50 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS04870 8fd98e590e12000de7baee4b6fb2f32a 115 PRINTS PR00061 Ribosomal protein L19 signature 4 33 1.6E-41 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS04870 8fd98e590e12000de7baee4b6fb2f32a 115 PRINTS PR00061 Ribosomal protein L19 signature 88 113 1.6E-41 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS04870 8fd98e590e12000de7baee4b6fb2f32a 115 PRINTS PR00061 Ribosomal protein L19 signature 34 63 1.6E-41 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS04870 8fd98e590e12000de7baee4b6fb2f32a 115 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 6.7E-51 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS04870 8fd98e590e12000de7baee4b6fb2f32a 115 SUPERFAMILY SSF50104 2 114 1.2E-47 T 28-03-2018 IPR008991 Translation protein SH3-like domain MKLM6_RS12540 3aa69de76eacf37dc360f8dd0183539f 945 PIRSF PIRSF000157 1 936 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MKLM6_RS12540 3aa69de76eacf37dc360f8dd0183539f 945 Gene3D G3DSA:3.40.50.970 165 522 1.7E-86 T 28-03-2018 MKLM6_RS12540 3aa69de76eacf37dc360f8dd0183539f 945 Pfam PF00676 Dehydrogenase E1 component 213 517 1.0E-50 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 MKLM6_RS12540 3aa69de76eacf37dc360f8dd0183539f 945 SUPERFAMILY SSF52518 578 795 4.12E-52 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS12540 3aa69de76eacf37dc360f8dd0183539f 945 Gene3D G3DSA:1.10.287.1150 82 164 3.2E-19 T 28-03-2018 MKLM6_RS12540 3aa69de76eacf37dc360f8dd0183539f 945 Gene3D G3DSA:3.40.50.970 594 803 4.1E-55 T 28-03-2018 MKLM6_RS12540 3aa69de76eacf37dc360f8dd0183539f 945 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 793 934 2.0E-47 T 28-03-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MKLM6_RS12540 3aa69de76eacf37dc360f8dd0183539f 945 SUPERFAMILY SSF52518 121 548 1.1E-85 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS12540 3aa69de76eacf37dc360f8dd0183539f 945 SMART SM00861 595 788 2.2E-57 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MKLM6_RS12540 3aa69de76eacf37dc360f8dd0183539f 945 Pfam PF02779 Transketolase, pyrimidine binding domain 594 789 2.2E-62 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MKLM6_RS12540 3aa69de76eacf37dc360f8dd0183539f 945 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 16 933 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MKLM6_RS12540 3aa69de76eacf37dc360f8dd0183539f 945 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 11 50 8.5E-12 T 28-03-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 SUPERFAMILY SSF55785 384 498 1.44E-28 T 28-03-2018 IPR000014 PAS domain MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 Gene3D G3DSA:3.60.40.10 506 747 3.1E-37 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 Pfam PF00989 PAS fold 373 486 5.5E-14 T 28-03-2018 IPR013767 PAS fold GO:0006355 MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 SMART SM00091 372 439 7.3E-8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 SMART SM00091 249 315 2.2E-6 T 28-03-2018 IPR000014 PAS domain MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 SMART SM00091 8 73 7.8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 SMART SM00091 123 189 2.4E-8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 369 495 1.1E-26 T 28-03-2018 IPR000014 PAS domain MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 245 367 1.5E-14 T 28-03-2018 IPR000014 PAS domain MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 126 244 2.0E-23 T 28-03-2018 IPR000014 PAS domain MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 Pfam PF13426 PAS domain 265 359 1.4E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 Pfam PF13426 PAS domain 135 235 4.9E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 Pfam PF13426 PAS domain 28 89 0.022 T 28-03-2018 IPR000014 PAS domain MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 SMART SM00086 195 237 2.0E-8 T 28-03-2018 IPR001610 PAC motif MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 SMART SM00086 449 489 0.091 T 28-03-2018 IPR001610 PAC motif MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 SMART SM00086 318 360 0.0014 T 28-03-2018 IPR001610 PAC motif MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 Gene3D G3DSA:3.30.450.20 2 116 1.2E-7 T 28-03-2018 MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 SUPERFAMILY SSF55785 128 235 8.9E-28 T 28-03-2018 IPR000014 PAS domain MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 Gene3D G3DSA:3.30.450.20 124 239 2.7E-30 T 28-03-2018 MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 SUPERFAMILY SSF55785 234 358 1.02E-19 T 28-03-2018 IPR000014 PAS domain MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 SUPERFAMILY SSF81606 542 745 2.28E-8 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 SMART SM00331 528 746 1.9E-47 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 SUPERFAMILY SSF55785 29 92 2.23E-6 T 28-03-2018 IPR000014 PAS domain MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 Gene3D G3DSA:3.30.450.20 360 505 9.3E-30 T 28-03-2018 MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 Gene3D G3DSA:3.30.450.20 240 359 1.6E-23 T 28-03-2018 MKLM6_RS16050 fe503082c92691febcb8410cd84f10ff 747 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 555 746 3.4E-51 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS22750 0d0b4c8de2eeb6675c92c4eb4f3c9a0a 351 SUPERFAMILY SSF110849 80 140 2.09E-5 T 28-03-2018 IPR003115 ParB/Sulfiredoxin MKLM6_RS22750 0d0b4c8de2eeb6675c92c4eb4f3c9a0a 351 Gene3D G3DSA:3.90.1530.10 33 196 9.2E-13 T 28-03-2018 MKLM6_RS08115 b672d37b9d4965825637a7ce5e47fea3 432 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 16 404 2.1E-25 T 28-03-2018 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) MKLM6_RS08115 b672d37b9d4965825637a7ce5e47fea3 432 Gene3D G3DSA:2.40.160.60 24 432 4.3E-46 T 28-03-2018 MKLM6_RS08115 b672d37b9d4965825637a7ce5e47fea3 432 SUPERFAMILY SSF56935 25 432 6.32E-44 T 28-03-2018 MKLM6_RS12695 0a1baa214bc82819ceae605f09d84b85 144 SUPERFAMILY SSF55961 4 143 3.74E-30 T 28-03-2018 MKLM6_RS12695 0a1baa214bc82819ceae605f09d84b85 144 Gene3D G3DSA:3.30.530.20 1 144 2.0E-25 T 28-03-2018 IPR023393 START-like domain MKLM6_RS12695 0a1baa214bc82819ceae605f09d84b85 144 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 11 134 6.7E-27 T 28-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 MKLM6_RS10470 7427bbea75078397c8170d184435f195 635 Gene3D G3DSA:2.40.160.10 168 635 3.1E-27 T 28-03-2018 MKLM6_RS10470 7427bbea75078397c8170d184435f195 635 SUPERFAMILY SSF56935 250 444 7.33E-10 T 28-03-2018 MKLM6_RS10470 7427bbea75078397c8170d184435f195 635 SUPERFAMILY SSF56935 484 616 7.33E-10 T 28-03-2018 MKLM6_RS10470 7427bbea75078397c8170d184435f195 635 Pfam PF16930 Putative porin 40 635 1.2E-165 T 28-03-2018 IPR032638 Putative bacterial porin MKLM6_RS21220 7427bbea75078397c8170d184435f195 635 Gene3D G3DSA:2.40.160.10 168 635 3.1E-27 T 28-03-2018 MKLM6_RS21220 7427bbea75078397c8170d184435f195 635 SUPERFAMILY SSF56935 250 444 7.33E-10 T 28-03-2018 MKLM6_RS21220 7427bbea75078397c8170d184435f195 635 SUPERFAMILY SSF56935 484 616 7.33E-10 T 28-03-2018 MKLM6_RS21220 7427bbea75078397c8170d184435f195 635 Pfam PF16930 Putative porin 40 635 1.2E-165 T 28-03-2018 IPR032638 Putative bacterial porin MKLM6_RS10045 2dced9f169b3ada9e6a9d7e2cfea91db 123 SUPERFAMILY SSF81343 1 121 1.59E-31 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MKLM6_RS10045 2dced9f169b3ada9e6a9d7e2cfea91db 123 Gene3D G3DSA:1.20.1300.10 13 123 2.7E-27 T 28-03-2018 MKLM6_RS10045 2dced9f169b3ada9e6a9d7e2cfea91db 123 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 1 117 6.8E-27 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MKLM6_RS10045 2dced9f169b3ada9e6a9d7e2cfea91db 123 ProSitePatterns PS01000 Succinate dehydrogenase cytochrome b subunit signature 1. 5 29 - T 28-03-2018 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MKLM6_RS10045 2dced9f169b3ada9e6a9d7e2cfea91db 123 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 4 121 8.9E-35 T 28-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MKLM6_RS10045 2dced9f169b3ada9e6a9d7e2cfea91db 123 ProSitePatterns PS01001 Succinate dehydrogenase cytochrome b subunit signature 2. 80 93 - T 28-03-2018 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MKLM6_RS10045 2dced9f169b3ada9e6a9d7e2cfea91db 123 PIRSF PIRSF000178 1 123 5.8E-34 T 28-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MKLM6_RS10045 2dced9f169b3ada9e6a9d7e2cfea91db 123 Gene3D G3DSA:1.20.5.540 1 12 6.9E-5 T 28-03-2018 MKLM6_RS08435 f1aa51908e0e9e3189bbd05d27edd67e 355 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 47 60 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MKLM6_RS08435 f1aa51908e0e9e3189bbd05d27edd67e 355 SUPERFAMILY SSF52540 24 265 2.5E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS08435 f1aa51908e0e9e3189bbd05d27edd67e 355 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 109 124 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MKLM6_RS08435 f1aa51908e0e9e3189bbd05d27edd67e 355 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 236 245 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site MKLM6_RS08435 f1aa51908e0e9e3189bbd05d27edd67e 355 Pfam PF00158 Sigma-54 interaction domain 25 189 1.5E-67 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MKLM6_RS08435 f1aa51908e0e9e3189bbd05d27edd67e 355 Gene3D G3DSA:1.10.10.60 270 342 1.6E-10 T 28-03-2018 MKLM6_RS08435 f1aa51908e0e9e3189bbd05d27edd67e 355 SUPERFAMILY SSF46689 236 341 7.62E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS08435 f1aa51908e0e9e3189bbd05d27edd67e 355 Pfam PF02954 Bacterial regulatory protein, Fis family 300 336 4.0E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS08435 f1aa51908e0e9e3189bbd05d27edd67e 355 SMART SM00382 43 186 6.3E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS08435 f1aa51908e0e9e3189bbd05d27edd67e 355 Gene3D G3DSA:3.40.50.300 18 194 4.3E-25 T 28-03-2018 MKLM6_RS08435 f1aa51908e0e9e3189bbd05d27edd67e 355 Gene3D G3DSA:1.10.8.60 196 267 6.4E-21 T 28-03-2018 MKLM6_RS00100 0d91eb0c01b9da2a4d4b87b5eab53305 2029 Gene3D G3DSA:3.40.50.300 235 266 0.0069 T 28-03-2018 MKLM6_RS00100 0d91eb0c01b9da2a4d4b87b5eab53305 2029 Gene3D G3DSA:3.40.50.300 267 738 0.002 T 28-03-2018 MKLM6_RS00100 0d91eb0c01b9da2a4d4b87b5eab53305 2029 Gene3D G3DSA:1.25.40.10 1336 1696 0.039 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS00100 0d91eb0c01b9da2a4d4b87b5eab53305 2029 SUPERFAMILY SSF52540 245 465 3.94E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS02510 131f450576681dcf17fcb79705cb59fc 305 Pfam PF01218 Coproporphyrinogen III oxidase 10 303 6.5E-138 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MKLM6_RS02510 131f450576681dcf17fcb79705cb59fc 305 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 167 191 - T 28-03-2018 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MKLM6_RS02510 131f450576681dcf17fcb79705cb59fc 305 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 4 278 58.084 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MKLM6_RS02510 131f450576681dcf17fcb79705cb59fc 305 PRINTS PR00073 Coprogen oxidase signature 163 192 9.2E-88 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MKLM6_RS02510 131f450576681dcf17fcb79705cb59fc 305 PRINTS PR00073 Coprogen oxidase signature 263 289 9.2E-88 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MKLM6_RS02510 131f450576681dcf17fcb79705cb59fc 305 PRINTS PR00073 Coprogen oxidase signature 49 70 9.2E-88 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MKLM6_RS02510 131f450576681dcf17fcb79705cb59fc 305 PRINTS PR00073 Coprogen oxidase signature 235 262 9.2E-88 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MKLM6_RS02510 131f450576681dcf17fcb79705cb59fc 305 PRINTS PR00073 Coprogen oxidase signature 32 48 9.2E-88 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MKLM6_RS02510 131f450576681dcf17fcb79705cb59fc 305 PRINTS PR00073 Coprogen oxidase signature 91 115 9.2E-88 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MKLM6_RS02510 131f450576681dcf17fcb79705cb59fc 305 PRINTS PR00073 Coprogen oxidase signature 126 148 9.2E-88 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MKLM6_RS02510 131f450576681dcf17fcb79705cb59fc 305 Gene3D G3DSA:3.40.1500.10 1 303 2.3E-145 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MKLM6_RS02510 131f450576681dcf17fcb79705cb59fc 305 SUPERFAMILY SSF102886 6 303 3.4E-143 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MKLM6_RS02510 131f450576681dcf17fcb79705cb59fc 305 PIRSF PIRSF000166 1 304 2.0E-133 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MKLM6_RS15835 3fd5d02ff7c02d366e2e842a329baf05 509 Gene3D G3DSA:3.40.50.2000 179 347 4.0E-18 T 28-03-2018 MKLM6_RS15835 3fd5d02ff7c02d366e2e842a329baf05 509 SUPERFAMILY SSF53756 16 361 2.83E-13 T 28-03-2018 MKLM6_RS15835 3fd5d02ff7c02d366e2e842a329baf05 509 SUPERFAMILY SSF55729 362 497 2.93E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS15835 3fd5d02ff7c02d366e2e842a329baf05 509 Gene3D G3DSA:3.40.50.2000 11 116 1.1E-8 T 28-03-2018 MKLM6_RS15835 3fd5d02ff7c02d366e2e842a329baf05 509 Pfam PF13302 Acetyltransferase (GNAT) domain 363 496 2.3E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 MKLM6_RS15835 3fd5d02ff7c02d366e2e842a329baf05 509 TIGRFAM TIGR03590 PseG: UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase 4 297 7.1E-92 T 28-03-2018 IPR020023 UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase MKLM6_RS15835 3fd5d02ff7c02d366e2e842a329baf05 509 Gene3D G3DSA:3.40.630.30 362 500 1.1E-17 T 28-03-2018 MKLM6_RS12185 6505b5f9083f7d40dfbe8112278b26b8 98 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 7 78 1.7E-10 T 28-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 MKLM6_RS12185 6505b5f9083f7d40dfbe8112278b26b8 98 SUPERFAMILY SSF143430 6 78 2.22E-21 T 28-03-2018 MKLM6_RS12185 6505b5f9083f7d40dfbe8112278b26b8 98 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 6 97 14.981 T 28-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 MKLM6_RS12185 6505b5f9083f7d40dfbe8112278b26b8 98 Pfam PF09827 CRISPR associated protein Cas2 7 72 3.6E-16 T 28-03-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 MKLM6_RS12185 6505b5f9083f7d40dfbe8112278b26b8 98 Gene3D G3DSA:3.30.70.240 2 98 6.9E-23 T 28-03-2018 MKLM6_RS09055 2c8c5925b39002f2fd5ae7b3e8a05883 366 SUPERFAMILY SSF56059 109 275 5.48E-15 T 28-03-2018 MKLM6_RS09055 2c8c5925b39002f2fd5ae7b3e8a05883 366 Pfam PF02655 ATP-grasp domain 119 264 3.6E-14 T 28-03-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 MKLM6_RS09055 2c8c5925b39002f2fd5ae7b3e8a05883 366 Gene3D G3DSA:3.30.470.20 115 355 7.1E-16 T 28-03-2018 MKLM6_RS09055 2c8c5925b39002f2fd5ae7b3e8a05883 366 Gene3D G3DSA:3.40.50.20 14 114 1.5E-6 T 28-03-2018 MKLM6_RS09055 2c8c5925b39002f2fd5ae7b3e8a05883 366 PIRSF PIRSF016817 2 365 2.0E-97 T 28-03-2018 IPR016677 Uncharacterised conserved protein UCP016817, ATP-dependent carboligase MKLM6_RS01525 54106a68600bccc640c30691f3c6b336 335 SUPERFAMILY SSF47648 1 69 2.49E-20 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 MKLM6_RS01525 54106a68600bccc640c30691f3c6b336 335 Pfam PF00591 Glycosyl transferase family, a/b domain 74 325 1.9E-95 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MKLM6_RS01525 54106a68600bccc640c30691f3c6b336 335 SUPERFAMILY SSF52418 73 334 1.13E-93 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MKLM6_RS01525 54106a68600bccc640c30691f3c6b336 335 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 5 334 37.385 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 MKLM6_RS01525 54106a68600bccc640c30691f3c6b336 335 Gene3D G3DSA:1.20.970.10 1 70 1.1E-23 T 28-03-2018 MKLM6_RS01525 54106a68600bccc640c30691f3c6b336 335 Gene3D G3DSA:3.40.1030.10 71 335 2.2E-102 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MKLM6_RS01525 54106a68600bccc640c30691f3c6b336 335 Pfam PF02885 Glycosyl transferase family, helical bundle domain 7 64 7.3E-21 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 MKLM6_RS01525 54106a68600bccc640c30691f3c6b336 335 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 7 333 2.2E-123 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 MKLM6_RS11225 2f5fb2803f027f4d50fa74ec2aa630b7 617 Pfam PF00733 Asparagine synthase 253 575 9.0E-52 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 MKLM6_RS11225 2f5fb2803f027f4d50fa74ec2aa630b7 617 Gene3D G3DSA:3.60.20.10 1 225 9.1E-52 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MKLM6_RS11225 2f5fb2803f027f4d50fa74ec2aa630b7 617 PIRSF PIRSF001589 1 601 7.7E-126 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MKLM6_RS11225 2f5fb2803f027f4d50fa74ec2aa630b7 617 SUPERFAMILY SSF52402 224 391 7.82E-42 T 28-03-2018 MKLM6_RS11225 2f5fb2803f027f4d50fa74ec2aa630b7 617 SUPERFAMILY SSF52402 486 576 7.82E-42 T 28-03-2018 MKLM6_RS11225 2f5fb2803f027f4d50fa74ec2aa630b7 617 Gene3D G3DSA:3.40.50.620 226 601 7.3E-39 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS11225 2f5fb2803f027f4d50fa74ec2aa630b7 617 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 567 2.6E-116 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MKLM6_RS11225 2f5fb2803f027f4d50fa74ec2aa630b7 617 Pfam PF13537 Glutamine amidotransferase domain 51 170 4.7E-45 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain MKLM6_RS11225 2f5fb2803f027f4d50fa74ec2aa630b7 617 SUPERFAMILY SSF56235 1 228 1.03E-62 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MKLM6_RS09685 fd30be846aa85d202f6c27c5e96dc3b6 872 Gene3D G3DSA:3.30.450.20 541 709 1.7E-8 T 28-03-2018 MKLM6_RS09685 fd30be846aa85d202f6c27c5e96dc3b6 872 SUPERFAMILY SSF47757 236 307 4.45E-15 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MKLM6_RS09685 fd30be846aa85d202f6c27c5e96dc3b6 872 Gene3D G3DSA:1.10.155.10 235 301 7.0E-16 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MKLM6_RS09685 fd30be846aa85d202f6c27c5e96dc3b6 872 Pfam PF01339 CheB methylesterase 39 213 3.6E-53 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MKLM6_RS09685 fd30be846aa85d202f6c27c5e96dc3b6 872 Pfam PF03705 CheR methyltransferase, all-alpha domain 241 291 5.2E-15 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MKLM6_RS09685 fd30be846aa85d202f6c27c5e96dc3b6 872 SUPERFAMILY SSF52738 33 220 4.18E-56 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MKLM6_RS09685 fd30be846aa85d202f6c27c5e96dc3b6 872 Pfam PF01739 CheR methyltransferase, SAM binding domain 305 494 2.4E-50 T 28-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal MKLM6_RS09685 fd30be846aa85d202f6c27c5e96dc3b6 872 SMART SM00138 238 501 1.3E-73 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS09685 fd30be846aa85d202f6c27c5e96dc3b6 872 Pfam PF13596 PAS domain 750 854 1.1E-31 T 28-03-2018 MKLM6_RS09685 fd30be846aa85d202f6c27c5e96dc3b6 872 PRINTS PR00996 Glutamate methyltransferase family signature 297 309 6.2E-25 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS09685 fd30be846aa85d202f6c27c5e96dc3b6 872 PRINTS PR00996 Glutamate methyltransferase family signature 337 357 6.2E-25 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS09685 fd30be846aa85d202f6c27c5e96dc3b6 872 PRINTS PR00996 Glutamate methyltransferase family signature 375 391 6.2E-25 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS09685 fd30be846aa85d202f6c27c5e96dc3b6 872 PRINTS PR00996 Glutamate methyltransferase family signature 441 455 6.2E-25 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS09685 fd30be846aa85d202f6c27c5e96dc3b6 872 PRINTS PR00996 Glutamate methyltransferase family signature 460 483 6.2E-25 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS09685 fd30be846aa85d202f6c27c5e96dc3b6 872 PRINTS PR00996 Glutamate methyltransferase family signature 260 273 6.2E-25 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS09685 fd30be846aa85d202f6c27c5e96dc3b6 872 SUPERFAMILY SSF55785 761 865 2.09E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS09685 fd30be846aa85d202f6c27c5e96dc3b6 872 Gene3D G3DSA:3.40.50.150 303 503 7.4E-39 T 28-03-2018 MKLM6_RS09685 fd30be846aa85d202f6c27c5e96dc3b6 872 SUPERFAMILY SSF53335 304 500 2.17E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS09685 fd30be846aa85d202f6c27c5e96dc3b6 872 Gene3D G3DSA:3.40.50.150 710 753 2.2E-4 T 28-03-2018 MKLM6_RS09685 fd30be846aa85d202f6c27c5e96dc3b6 872 Gene3D G3DSA:3.40.50.180 27 225 1.2E-65 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MKLM6_RS09685 fd30be846aa85d202f6c27c5e96dc3b6 872 Gene3D G3DSA:3.30.450.20 754 871 5.8E-17 T 28-03-2018 MKLM6_RS20260 ddc94e7800d4ee2eb364cd24dfa5d1b8 896 Gene3D G3DSA:1.10.1780.10 2 163 7.6E-17 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 MKLM6_RS20260 ddc94e7800d4ee2eb364cd24dfa5d1b8 896 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 234 367 3.2E-9 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MKLM6_RS20260 ddc94e7800d4ee2eb364cd24dfa5d1b8 896 Gene3D G3DSA:1.10.8.60 817 896 4.5E-12 T 28-03-2018 MKLM6_RS20260 ddc94e7800d4ee2eb364cd24dfa5d1b8 896 Gene3D G3DSA:3.40.50.300 583 816 9.1E-36 T 28-03-2018 MKLM6_RS20260 ddc94e7800d4ee2eb364cd24dfa5d1b8 896 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 325 337 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 MKLM6_RS20260 ddc94e7800d4ee2eb364cd24dfa5d1b8 896 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 708 726 3.2E-30 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 MKLM6_RS20260 ddc94e7800d4ee2eb364cd24dfa5d1b8 896 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 634 652 3.2E-30 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 MKLM6_RS20260 ddc94e7800d4ee2eb364cd24dfa5d1b8 896 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 679 697 3.2E-30 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 MKLM6_RS20260 ddc94e7800d4ee2eb364cd24dfa5d1b8 896 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 741 755 3.2E-30 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 MKLM6_RS20260 ddc94e7800d4ee2eb364cd24dfa5d1b8 896 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 802 876 2.2E-13 T 28-03-2018 IPR019489 Clp ATPase, C-terminal MKLM6_RS20260 ddc94e7800d4ee2eb364cd24dfa5d1b8 896 Pfam PF07724 AAA domain (Cdc48 subfamily) 629 796 4.0E-38 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MKLM6_RS20260 ddc94e7800d4ee2eb364cd24dfa5d1b8 896 SUPERFAMILY SSF52540 579 883 5.14E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS20260 ddc94e7800d4ee2eb364cd24dfa5d1b8 896 Gene3D G3DSA:1.10.8.60 375 580 9.8E-38 T 28-03-2018 MKLM6_RS20260 ddc94e7800d4ee2eb364cd24dfa5d1b8 896 SUPERFAMILY SSF81923 12 130 2.94E-12 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 MKLM6_RS20260 ddc94e7800d4ee2eb364cd24dfa5d1b8 896 Gene3D G3DSA:3.40.50.300 188 373 6.0E-23 T 28-03-2018 MKLM6_RS20260 ddc94e7800d4ee2eb364cd24dfa5d1b8 896 SUPERFAMILY SSF52540 190 578 1.21E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS20260 ddc94e7800d4ee2eb364cd24dfa5d1b8 896 SMART SM01086 802 894 9.4E-13 T 28-03-2018 IPR019489 Clp ATPase, C-terminal MKLM6_RS20260 ddc94e7800d4ee2eb364cd24dfa5d1b8 896 TIGRFAM TIGR03345 VI_ClpV1: type VI secretion ATPase, ClpV1 family 13 887 0.0 T 28-03-2018 IPR017729 Type VI secretion system, ATPase ClpV1 MKLM6_RS20260 ddc94e7800d4ee2eb364cd24dfa5d1b8 896 SMART SM00382 229 374 1.9E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS20260 ddc94e7800d4ee2eb364cd24dfa5d1b8 896 SMART SM00382 630 773 2.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS11270 c12a71e6998ae7e48d0c980f32126fb6 202 SMART SM00028 118 151 3.2E-5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS11270 c12a71e6998ae7e48d0c980f32126fb6 202 SMART SM00028 152 185 13.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS11270 c12a71e6998ae7e48d0c980f32126fb6 202 Gene3D G3DSA:1.25.40.10 150 197 1.1E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS11270 c12a71e6998ae7e48d0c980f32126fb6 202 Pfam PF14559 Tetratricopeptide repeat 131 192 2.3E-8 T 28-03-2018 MKLM6_RS11270 c12a71e6998ae7e48d0c980f32126fb6 202 SUPERFAMILY SSF48452 118 195 2.8E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS11270 c12a71e6998ae7e48d0c980f32126fb6 202 Gene3D G3DSA:1.20.58.280 117 149 3.4E-7 T 28-03-2018 MKLM6_RS21410 b5976c56ce1e798ec7316a5a866cf0d6 428 Pfam PF13460 NAD(P)H-binding 7 197 3.4E-14 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS21410 b5976c56ce1e798ec7316a5a866cf0d6 428 SUPERFAMILY SSF51735 1 218 4.78E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS21410 b5976c56ce1e798ec7316a5a866cf0d6 428 Pfam PF13781 DoxX-like family 317 417 9.8E-25 T 28-03-2018 IPR025695 DoxX-like family MKLM6_RS21410 b5976c56ce1e798ec7316a5a866cf0d6 428 Gene3D G3DSA:3.40.50.720 1 300 6.4E-42 T 28-03-2018 MKLM6_RS21410 b5976c56ce1e798ec7316a5a866cf0d6 428 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 9.3E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS21410 b5976c56ce1e798ec7316a5a866cf0d6 428 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 65 76 9.3E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS21410 b5976c56ce1e798ec7316a5a866cf0d6 428 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 100 116 9.3E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS21410 b5976c56ce1e798ec7316a5a866cf0d6 428 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 143 9.3E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS09490 eac18633186d6ac180c78f4466e7aff5 120 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 71 8.0E-20 T 28-03-2018 MKLM6_RS09490 eac18633186d6ac180c78f4466e7aff5 120 Pfam PF00453 Ribosomal protein L20 3 108 6.6E-49 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS09490 eac18633186d6ac180c78f4466e7aff5 120 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS09490 eac18633186d6ac180c78f4466e7aff5 120 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 29.984 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS09490 eac18633186d6ac180c78f4466e7aff5 120 Gene3D G3DSA:1.10.1900.20 55 116 4.1E-25 T 28-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS09490 eac18633186d6ac180c78f4466e7aff5 120 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 112 4.1E-50 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS09490 eac18633186d6ac180c78f4466e7aff5 120 SUPERFAMILY SSF74731 3 114 1.29E-48 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS09490 eac18633186d6ac180c78f4466e7aff5 120 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.0E-40 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS09490 eac18633186d6ac180c78f4466e7aff5 120 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.0E-40 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS09490 eac18633186d6ac180c78f4466e7aff5 120 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.0E-40 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS08090 930b066082443a1af7337da1db719687 393 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 150 172 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MKLM6_RS08090 930b066082443a1af7337da1db719687 393 Pfam PF01066 CDP-alcohol phosphatidyltransferase 106 171 1.1E-6 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MKLM6_RS19635 f5734f58f805a4bde44fc4518c583d1f 431 Gene3D G3DSA:1.10.580.10 342 408 4.4E-8 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain MKLM6_RS19635 f5734f58f805a4bde44fc4518c583d1f 431 PIRSF PIRSF001369 39 431 2.8E-164 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type MKLM6_RS19635 f5734f58f805a4bde44fc4518c583d1f 431 SUPERFAMILY SSF48256 13 431 5.5E-165 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 MKLM6_RS19635 f5734f58f805a4bde44fc4518c583d1f 431 ProSitePatterns PS00480 Citrate synthase signature. 305 317 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MKLM6_RS19635 f5734f58f805a4bde44fc4518c583d1f 431 Gene3D G3DSA:1.10.580.10 33 300 1.3E-88 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain MKLM6_RS19635 f5734f58f805a4bde44fc4518c583d1f 431 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 15 425 1.7E-232 T 28-03-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 MKLM6_RS19635 f5734f58f805a4bde44fc4518c583d1f 431 Pfam PF00285 Citrate synthase, C-terminal domain 48 414 8.9E-131 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 MKLM6_RS19635 f5734f58f805a4bde44fc4518c583d1f 431 PRINTS PR00143 Citrate synthase signature 382 396 4.3E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 MKLM6_RS19635 f5734f58f805a4bde44fc4518c583d1f 431 PRINTS PR00143 Citrate synthase signature 362 378 4.3E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 MKLM6_RS19635 f5734f58f805a4bde44fc4518c583d1f 431 PRINTS PR00143 Citrate synthase signature 221 236 4.3E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 MKLM6_RS19635 f5734f58f805a4bde44fc4518c583d1f 431 PRINTS PR00143 Citrate synthase signature 298 318 4.3E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 MKLM6_RS19635 f5734f58f805a4bde44fc4518c583d1f 431 PRINTS PR00143 Citrate synthase signature 167 180 4.3E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 MKLM6_RS19635 f5734f58f805a4bde44fc4518c583d1f 431 PRINTS PR00143 Citrate synthase signature 243 271 4.3E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 MKLM6_RS01760 c81ea269c77d719d2337666aef636110 301 SUPERFAMILY SSF52540 16 279 8.57E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS01760 c81ea269c77d719d2337666aef636110 301 Gene3D G3DSA:1.10.8.300 196 292 4.7E-20 T 28-03-2018 MKLM6_RS01760 c81ea269c77d719d2337666aef636110 301 Gene3D G3DSA:3.40.50.300 16 182 5.7E-27 T 28-03-2018 MKLM6_RS01760 c81ea269c77d719d2337666aef636110 301 PIRSF PIRSF002849 1 299 2.0E-114 T 28-03-2018 MKLM6_RS01760 c81ea269c77d719d2337666aef636110 301 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 35 165 1.2E-62 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 MKLM6_RS05965 099088c81b851348e9d7c160eaf52005 263 Gene3D G3DSA:3.90.550.10 1 229 1.2E-22 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS05965 099088c81b851348e9d7c160eaf52005 263 SUPERFAMILY SSF53448 1 134 1.33E-25 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS05965 099088c81b851348e9d7c160eaf52005 263 Pfam PF00535 Glycosyl transferase family 2 3 93 1.3E-16 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MKLM6_RS17335 647feffd8aeb063baefdf687d233489d 183 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 25 172 6.3E-8 T 28-03-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like MKLM6_RS17335 647feffd8aeb063baefdf687d233489d 183 Gene3D G3DSA:2.50.20.10 7 174 2.7E-14 T 28-03-2018 MKLM6_RS17335 647feffd8aeb063baefdf687d233489d 183 SUPERFAMILY SSF89392 10 167 1.18E-13 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX MKLM6_RS22470 afc54a9e892e8ae2c9e700eb7a8db512 137 Pfam PF01464 Transglycosylase SLT domain 36 119 1.2E-6 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 MKLM6_RS22470 afc54a9e892e8ae2c9e700eb7a8db512 137 Gene3D G3DSA:1.10.530.10 1 136 1.2E-9 T 28-03-2018 MKLM6_RS22470 afc54a9e892e8ae2c9e700eb7a8db512 137 SUPERFAMILY SSF53955 15 23 2.53E-13 T 28-03-2018 IPR023346 Lysozyme-like domain MKLM6_RS22470 afc54a9e892e8ae2c9e700eb7a8db512 137 SUPERFAMILY SSF53955 50 131 2.53E-13 T 28-03-2018 IPR023346 Lysozyme-like domain MKLM6_RS01080 7bb9c190af20020ffd1d81fbc5f2d7fe 383 SUPERFAMILY SSF53756 2 380 4.24E-51 T 28-03-2018 MKLM6_RS01080 7bb9c190af20020ffd1d81fbc5f2d7fe 383 Gene3D G3DSA:3.40.50.2000 180 368 7.8E-32 T 28-03-2018 MKLM6_RS01080 7bb9c190af20020ffd1d81fbc5f2d7fe 383 Pfam PF00534 Glycosyl transferases group 1 191 355 1.8E-30 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 MKLM6_RS05170 cce8b281bbec3e3bf35db3670edba666 375 Gene3D G3DSA:3.40.50.880 152 375 4.0E-64 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS05170 cce8b281bbec3e3bf35db3670edba666 375 PRINTS PR00096 Glutamine amidotransferase superfamily signature 346 359 4.1E-11 T 28-03-2018 MKLM6_RS05170 cce8b281bbec3e3bf35db3670edba666 375 PRINTS PR00096 Glutamine amidotransferase superfamily signature 233 242 4.1E-11 T 28-03-2018 MKLM6_RS05170 cce8b281bbec3e3bf35db3670edba666 375 PRINTS PR00096 Glutamine amidotransferase superfamily signature 261 272 4.1E-11 T 28-03-2018 MKLM6_RS05170 cce8b281bbec3e3bf35db3670edba666 375 Pfam PF00117 Glutamine amidotransferase class-I 194 369 1.0E-46 T 28-03-2018 IPR017926 Glutamine amidotransferase MKLM6_RS05170 cce8b281bbec3e3bf35db3670edba666 375 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 261 277 2.2E-39 T 28-03-2018 MKLM6_RS05170 cce8b281bbec3e3bf35db3670edba666 375 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 303 314 2.2E-39 T 28-03-2018 MKLM6_RS05170 cce8b281bbec3e3bf35db3670edba666 375 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 191 205 2.2E-39 T 28-03-2018 MKLM6_RS05170 cce8b281bbec3e3bf35db3670edba666 375 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 230 244 2.2E-39 T 28-03-2018 MKLM6_RS05170 cce8b281bbec3e3bf35db3670edba666 375 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 278 295 2.2E-39 T 28-03-2018 MKLM6_RS05170 cce8b281bbec3e3bf35db3670edba666 375 Gene3D G3DSA:3.50.30.20 2 151 2.3E-59 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS05170 cce8b281bbec3e3bf35db3670edba666 375 PRINTS PR00097 Anthranilate synthase component II signature 261 272 1.5E-5 T 28-03-2018 MKLM6_RS05170 cce8b281bbec3e3bf35db3670edba666 375 PRINTS PR00097 Anthranilate synthase component II signature 233 242 1.5E-5 T 28-03-2018 MKLM6_RS05170 cce8b281bbec3e3bf35db3670edba666 375 PRINTS PR00097 Anthranilate synthase component II signature 346 359 1.5E-5 T 28-03-2018 MKLM6_RS05170 cce8b281bbec3e3bf35db3670edba666 375 SUPERFAMILY SSF52317 155 372 2.9E-60 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS05170 cce8b281bbec3e3bf35db3670edba666 375 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 5 132 1.9E-49 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS05170 cce8b281bbec3e3bf35db3670edba666 375 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 372 2.3E-146 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS05170 cce8b281bbec3e3bf35db3670edba666 375 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 3 375 48.555 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS05170 cce8b281bbec3e3bf35db3670edba666 375 SUPERFAMILY SSF52021 4 139 1.57E-55 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS05170 cce8b281bbec3e3bf35db3670edba666 375 SMART SM01097 3 133 4.5E-88 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS00460 b7edf53b7481293675405620175b0acf 476 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 331 471 1.7E-58 T 28-03-2018 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 MKLM6_RS00460 b7edf53b7481293675405620175b0acf 476 Gene3D G3DSA:3.40.1190.20 2 308 8.4E-56 T 28-03-2018 IPR029056 Ribokinase-like MKLM6_RS00460 b7edf53b7481293675405620175b0acf 476 SUPERFAMILY SSF53613 9 311 1.71E-55 T 28-03-2018 IPR029056 Ribokinase-like MKLM6_RS00460 b7edf53b7481293675405620175b0acf 476 Gene3D G3DSA:3.40.50.620 325 476 2.8E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS00460 b7edf53b7481293675405620175b0acf 476 Pfam PF00294 pfkB family carbohydrate kinase 10 300 2.0E-45 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB MKLM6_RS00460 b7edf53b7481293675405620175b0acf 476 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 340 406 3.7E-18 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MKLM6_RS00460 b7edf53b7481293675405620175b0acf 476 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 3 310 5.8E-124 T 28-03-2018 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 MKLM6_RS00460 b7edf53b7481293675405620175b0acf 476 Hamap MF_01603 Bifunctional protein HldE [hldE]. 2 473 42.001 T 28-03-2018 IPR023030 Bifunctional protein HldE GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 MKLM6_RS00460 b7edf53b7481293675405620175b0acf 476 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 48 72 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MKLM6_RS00460 b7edf53b7481293675405620175b0acf 476 SUPERFAMILY SSF52374 338 470 8.16E-25 T 28-03-2018 MKLM6_RS00460 b7edf53b7481293675405620175b0acf 476 Pfam PF01467 Cytidylyltransferase-like 343 434 6.9E-19 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MKLM6_RS07160 9ee3b6e4cad686206c8cd2e0ea3cde47 394 Pfam PF00990 Diguanylate cyclase, GGDEF domain 223 380 2.3E-45 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS07160 9ee3b6e4cad686206c8cd2e0ea3cde47 394 Gene3D G3DSA:3.30.70.270 216 391 8.1E-54 T 28-03-2018 MKLM6_RS07160 9ee3b6e4cad686206c8cd2e0ea3cde47 394 SMART SM00267 212 384 4.2E-56 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS07160 9ee3b6e4cad686206c8cd2e0ea3cde47 394 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 219 382 6.7E-50 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS07160 9ee3b6e4cad686206c8cd2e0ea3cde47 394 SUPERFAMILY SSF55073 228 385 5.1E-48 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 Gene3D G3DSA:3.30.230.10 495 616 2.0E-41 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 Gene3D G3DSA:2.40.30.10 278 397 6.4E-31 T 28-03-2018 MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 SUPERFAMILY SSF50447 268 405 4.86E-33 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 SUPERFAMILY SSF54980 606 694 2.63E-29 T 28-03-2018 IPR035647 EF-G domain III/V-like MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 48 63 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 SUPERFAMILY SSF54980 405 483 2.63E-21 T 28-03-2018 IPR035647 EF-G domain III/V-like MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 SMART SM00889 483 601 7.6E-62 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 Pfam PF14492 Elongation Factor G, domain II 407 481 7.1E-30 T 28-03-2018 MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 Pfam PF03144 Elongation factor Tu domain 2 327 394 2.2E-17 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 Hamap MF_00054_B Elongation factor G [fusA]. 3 694 103.064 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 Gene3D G3DSA:3.40.50.300 3 277 2.5E-53 T 28-03-2018 MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 Gene3D G3DSA:3.30.70.240 617 694 1.5E-28 T 28-03-2018 MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 Pfam PF00679 Elongation factor G C-terminus 603 689 3.5E-28 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 SMART SM00838 603 690 1.4E-45 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 Pfam PF03764 Elongation factor G, domain IV 482 599 2.3E-43 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 SUPERFAMILY SSF54211 482 602 3.03E-40 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 PRINTS PR00315 GTP-binding elongation factor signature 9 22 2.4E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 PRINTS PR00315 GTP-binding elongation factor signature 82 92 2.4E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 PRINTS PR00315 GTP-binding elongation factor signature 134 143 2.4E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 PRINTS PR00315 GTP-binding elongation factor signature 55 63 2.4E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 TIGRFAM TIGR00484 EF-G: translation elongation factor G 2 695 3.1E-296 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 Gene3D G3DSA:3.30.70.870 398 494 3.4E-31 T 28-03-2018 MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 183 1.3E-23 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 Pfam PF00009 Elongation factor Tu GTP binding domain 7 284 2.7E-57 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MKLM6_RS21505 673040971574da4a3cade12f85b178b1 703 SUPERFAMILY SSF52540 3 285 5.58E-96 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS19655 9ffe3cfbaf52bb7cdde896fe4c469d46 264 SUPERFAMILY SSF52172 7 131 1.24E-23 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS19655 9ffe3cfbaf52bb7cdde896fe4c469d46 264 SUPERFAMILY SSF52172 143 264 7.26E-29 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS19655 9ffe3cfbaf52bb7cdde896fe4c469d46 264 Gene3D G3DSA:3.40.50.2300 137 264 9.4E-29 T 28-03-2018 MKLM6_RS19655 9ffe3cfbaf52bb7cdde896fe4c469d46 264 Gene3D G3DSA:3.40.50.2300 4 135 2.6E-19 T 28-03-2018 MKLM6_RS19655 9ffe3cfbaf52bb7cdde896fe4c469d46 264 Pfam PF00072 Response regulator receiver domain 147 257 5.5E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS19655 9ffe3cfbaf52bb7cdde896fe4c469d46 264 Pfam PF00072 Response regulator receiver domain 11 123 3.3E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS19655 9ffe3cfbaf52bb7cdde896fe4c469d46 264 SMART SM00448 9 123 4.3E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS19655 9ffe3cfbaf52bb7cdde896fe4c469d46 264 SMART SM00448 145 259 1.2E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS15735 06cddeef251e3455d2f4835808c7dae6 267 SUPERFAMILY SSF53335 225 254 1.17E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS15735 06cddeef251e3455d2f4835808c7dae6 267 SUPERFAMILY SSF53335 22 174 1.17E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS15735 06cddeef251e3455d2f4835808c7dae6 267 Pfam PF08242 Methyltransferase domain 53 151 2.2E-13 T 28-03-2018 IPR013217 Methyltransferase type 12 MKLM6_RS15735 06cddeef251e3455d2f4835808c7dae6 267 Gene3D G3DSA:3.40.50.150 7 265 9.1E-27 T 28-03-2018 MKLM6_RS11290 c955bebbd0d92774a8056cc95b4a0074 503 TIGRFAM TIGR02914 EpsI_fam: EpsI family protein 339 496 5.8E-28 T 28-03-2018 IPR014263 Methanolan biosynthesis EpsI MKLM6_RS11290 c955bebbd0d92774a8056cc95b4a0074 503 TIGRFAM TIGR02602 8TM_EpsH: exosortase 37 273 1.7E-72 T 28-03-2018 IPR013426 Exosortase, EpsH MKLM6_RS11290 c955bebbd0d92774a8056cc95b4a0074 503 Pfam PF11984 Protein of unknown function (DUF3485) 307 498 3.3E-28 T 28-03-2018 IPR014263 Methanolan biosynthesis EpsI MKLM6_RS11290 c955bebbd0d92774a8056cc95b4a0074 503 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 180 271 1.6E-19 T 28-03-2018 IPR026392 Exosortase/Archaeosortase domain MKLM6_RS11290 c955bebbd0d92774a8056cc95b4a0074 503 TIGRFAM TIGR03109 exosortase_1: exosortase A 11 274 3.7E-94 T 28-03-2018 IPR017540 Exosortase 1 MKLM6_RS11290 c955bebbd0d92774a8056cc95b4a0074 503 Pfam PF09721 Transmembrane exosortase (Exosortase_EpsH) 25 272 1.9E-56 T 28-03-2018 IPR019127 Exosortase EpsH-related MKLM6_RS15180 e031665278e22af9745c98888b3255bb 457 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 455 3.7E-178 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 MKLM6_RS15180 e031665278e22af9745c98888b3255bb 457 SUPERFAMILY SSF52374 1 311 2.01E-99 T 28-03-2018 MKLM6_RS15180 e031665278e22af9745c98888b3255bb 457 Pfam PF09190 DALR domain 340 396 6.3E-21 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 MKLM6_RS15180 e031665278e22af9745c98888b3255bb 457 SMART SM00840 340 396 3.6E-26 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 MKLM6_RS15180 e031665278e22af9745c98888b3255bb 457 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 1.1E-30 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MKLM6_RS15180 e031665278e22af9745c98888b3255bb 457 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 1.1E-30 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MKLM6_RS15180 e031665278e22af9745c98888b3255bb 457 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 1.1E-30 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MKLM6_RS15180 e031665278e22af9745c98888b3255bb 457 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 1.1E-30 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MKLM6_RS15180 e031665278e22af9745c98888b3255bb 457 SUPERFAMILY SSF47323 316 454 3.4E-36 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS15180 e031665278e22af9745c98888b3255bb 457 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 455 39.879 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 MKLM6_RS15180 e031665278e22af9745c98888b3255bb 457 Gene3D G3DSA:3.40.50.620 1 305 5.2E-91 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS15180 e031665278e22af9745c98888b3255bb 457 Gene3D G3DSA:1.20.120.640 306 388 2.1E-20 T 28-03-2018 MKLM6_RS15180 e031665278e22af9745c98888b3255bb 457 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 312 6.6E-135 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 MKLM6_RS18570 9a9326e9f35cb7402bbeea0c3d64db0c 416 PIRSF PIRSF000445 1 416 1.4E-158 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MKLM6_RS18570 9a9326e9f35cb7402bbeea0c3d64db0c 416 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 416 30.899 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MKLM6_RS18570 9a9326e9f35cb7402bbeea0c3d64db0c 416 SUPERFAMILY SSF69742 1 156 1.11E-46 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MKLM6_RS18570 9a9326e9f35cb7402bbeea0c3d64db0c 416 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 97 120 - T 28-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MKLM6_RS18570 9a9326e9f35cb7402bbeea0c3d64db0c 416 Gene3D G3DSA:3.40.50.720 177 343 4.8E-24 T 28-03-2018 MKLM6_RS18570 9a9326e9f35cb7402bbeea0c3d64db0c 416 SUPERFAMILY SSF69075 315 415 2.88E-29 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MKLM6_RS18570 9a9326e9f35cb7402bbeea0c3d64db0c 416 SUPERFAMILY SSF51735 161 313 5.52E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS18570 9a9326e9f35cb7402bbeea0c3d64db0c 416 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 154 5.3E-50 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MKLM6_RS18570 9a9326e9f35cb7402bbeea0c3d64db0c 416 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 415 7.0E-142 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MKLM6_RS18570 9a9326e9f35cb7402bbeea0c3d64db0c 416 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 169 303 6.9E-48 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase MKLM6_RS18570 9a9326e9f35cb7402bbeea0c3d64db0c 416 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 318 415 6.7E-28 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MKLM6_RS18570 9a9326e9f35cb7402bbeea0c3d64db0c 416 Gene3D G3DSA:1.10.1200.70 344 416 4.5E-25 T 28-03-2018 MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 SUPERFAMILY SSF47226 807 913 1.57E-21 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 Gene3D G3DSA:3.30.565.10 344 510 8.3E-50 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 SMART SM00304 189 242 2.5E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 SMART SM00448 666 782 1.9E-43 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 SMART SM00448 525 643 1.9E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 PRINTS PR00344 Bacterial sensor protein C-terminal signature 491 504 1.3E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 PRINTS PR00344 Bacterial sensor protein C-terminal signature 467 485 1.3E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 446 1.3E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 PRINTS PR00344 Bacterial sensor protein C-terminal signature 450 460 1.3E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 Pfam PF01627 Hpt domain 828 910 1.1E-11 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 Pfam PF00672 HAMP domain 190 239 8.9E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 Pfam PF00072 Response regulator receiver domain 527 642 7.8E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 Pfam PF00072 Response regulator receiver domain 668 782 2.9E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 Gene3D G3DSA:3.40.50.2300 657 798 8.9E-45 T 28-03-2018 MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 SUPERFAMILY SSF158472 190 239 4.71E-7 T 28-03-2018 MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 SUPERFAMILY SSF55874 329 505 2.62E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 387 506 3.2E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 Pfam PF17152 Periplasmic sensor domain 43 150 1.9E-12 T 28-03-2018 IPR033417 Periplasmic sensor domain CHASE8 MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 Gene3D G3DSA:3.40.50.2300 524 656 1.1E-26 T 28-03-2018 MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 SMART SM00388 275 340 4.0E-26 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 Gene3D G3DSA:1.10.287.130 266 336 2.5E-18 T 28-03-2018 MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 SMART SM00073 819 912 1.4E-6 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 SUPERFAMILY SSF52172 522 647 6.4E-26 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 SUPERFAMILY SSF52172 663 787 5.27E-41 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 Gene3D G3DSA:1.20.120.160 801 916 8.3E-19 T 28-03-2018 MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 Pfam PF00512 His Kinase A (phospho-acceptor) domain 275 340 9.2E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 SMART SM00387 387 507 2.4E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13385 c50df3210520d8637ee8dd52a5abd466 917 SUPERFAMILY SSF47384 261 341 4.71E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS18335 c10d09b65695d25b8f0293802369478b 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18335 c10d09b65695d25b8f0293802369478b 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 9.0E-7 T 28-03-2018 MKLM6_RS18335 c10d09b65695d25b8f0293802369478b 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 2 37 2.0E-18 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18335 c10d09b65695d25b8f0293802369478b 37 Pfam PF00444 Ribosomal protein L36 2 37 3.7E-15 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18335 c10d09b65695d25b8f0293802369478b 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 15.688 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18335 c10d09b65695d25b8f0293802369478b 37 SUPERFAMILY SSF57840 2 37 1.44E-14 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS21510 604c3c89e62ffe11b634bae239390aff 107 Pfam PF11953 Domain of unknown function (DUF3470) 66 107 5.6E-21 T 28-03-2018 IPR022569 Ferredoxin, C-terminal MKLM6_RS21510 604c3c89e62ffe11b634bae239390aff 107 SUPERFAMILY SSF54862 3 95 2.03E-24 T 28-03-2018 MKLM6_RS21510 604c3c89e62ffe11b634bae239390aff 107 Gene3D G3DSA:3.30.70.20 46 106 1.5E-9 T 28-03-2018 MKLM6_RS21510 604c3c89e62ffe11b634bae239390aff 107 Gene3D G3DSA:3.30.70.20 2 45 5.1E-13 T 28-03-2018 MKLM6_RS21510 604c3c89e62ffe11b634bae239390aff 107 Pfam PF00037 4Fe-4S binding domain 34 55 3.7E-7 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MKLM6_RS21510 604c3c89e62ffe11b634bae239390aff 107 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.4E-16 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 MKLM6_RS21510 604c3c89e62ffe11b634bae239390aff 107 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.4E-16 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 MKLM6_RS21510 604c3c89e62ffe11b634bae239390aff 107 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.4E-16 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 MKLM6_RS21510 604c3c89e62ffe11b634bae239390aff 107 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MKLM6_RS21395 68debeed79a882af71ea7671ba820a68 195 Gene3D G3DSA:3.90.1570.10 2 184 1.2E-42 T 28-03-2018 MKLM6_RS21395 68debeed79a882af71ea7671ba820a68 195 Pfam PF05685 Putative restriction endonuclease 13 173 2.1E-29 T 28-03-2018 IPR008538 Domain of unknown function DUF820 MKLM6_RS21395 68debeed79a882af71ea7671ba820a68 195 SUPERFAMILY SSF52980 4 180 3.0E-26 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MKLM6_RS06310 c517f8092779c68090eacd6da65f1774 331 SUPERFAMILY SSF52540 7 207 3.76E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS06310 c517f8092779c68090eacd6da65f1774 331 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 217 327 1.2E-17 T 28-03-2018 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS06310 c517f8092779c68090eacd6da65f1774 331 Gene3D G3DSA:3.40.50.300 10 169 4.2E-25 T 28-03-2018 MKLM6_RS06310 c517f8092779c68090eacd6da65f1774 331 Gene3D G3DSA:1.20.272.10 212 331 1.2E-23 T 28-03-2018 MKLM6_RS06310 c517f8092779c68090eacd6da65f1774 331 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 14 201 3.1E-60 T 28-03-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS06310 c517f8092779c68090eacd6da65f1774 331 Pfam PF13177 DNA polymerase III, delta subunit 10 166 8.3E-45 T 28-03-2018 MKLM6_RS06310 c517f8092779c68090eacd6da65f1774 331 SUPERFAMILY SSF48019 229 327 5.1E-6 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MKLM6_RS18355 8298cea38224734273d0cf19b958ba04 168 Pfam PF03719 Ribosomal protein S5, C-terminal domain 90 159 8.0E-28 T 28-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18355 8298cea38224734273d0cf19b958ba04 168 Pfam PF00333 Ribosomal protein S5, N-terminal domain 13 76 1.9E-25 T 28-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18355 8298cea38224734273d0cf19b958ba04 168 Gene3D G3DSA:3.30.230.10 78 168 4.2E-27 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MKLM6_RS18355 8298cea38224734273d0cf19b958ba04 168 SUPERFAMILY SSF54768 11 77 5.13E-21 T 28-03-2018 MKLM6_RS18355 8298cea38224734273d0cf19b958ba04 168 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 165 32.646 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 MKLM6_RS18355 8298cea38224734273d0cf19b958ba04 168 ProSitePatterns PS00585 Ribosomal protein S5 signature. 30 62 - T 28-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site MKLM6_RS18355 8298cea38224734273d0cf19b958ba04 168 SUPERFAMILY SSF54211 81 160 1.39E-23 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS18355 8298cea38224734273d0cf19b958ba04 168 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 12 164 5.4E-61 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 MKLM6_RS18355 8298cea38224734273d0cf19b958ba04 168 Gene3D G3DSA:3.30.160.20 12 73 2.6E-23 T 28-03-2018 MKLM6_RS13965 8792331637eec0a29a7f58c1b133d703 548 Gene3D G3DSA:1.20.120.50 1 133 1.3E-32 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 MKLM6_RS13965 8792331637eec0a29a7f58c1b133d703 548 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 339 452 6.7E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13965 8792331637eec0a29a7f58c1b133d703 548 Gene3D G3DSA:1.10.287.130 217 288 9.4E-17 T 28-03-2018 MKLM6_RS13965 8792331637eec0a29a7f58c1b133d703 548 SUPERFAMILY SSF47384 212 293 1.96E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS13965 8792331637eec0a29a7f58c1b133d703 548 SUPERFAMILY SSF47188 1 131 8.24E-28 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 MKLM6_RS13965 8792331637eec0a29a7f58c1b133d703 548 SMART SM00388 227 292 1.7E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS13965 8792331637eec0a29a7f58c1b133d703 548 Pfam PF01814 Hemerythrin HHE cation binding domain 13 130 1.2E-11 T 28-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 MKLM6_RS13965 8792331637eec0a29a7f58c1b133d703 548 SUPERFAMILY SSF55874 282 450 8.38E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13965 8792331637eec0a29a7f58c1b133d703 548 Pfam PF00512 His Kinase A (phospho-acceptor) domain 227 292 1.4E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS13965 8792331637eec0a29a7f58c1b133d703 548 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 5 131 7.6E-29 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 MKLM6_RS13965 8792331637eec0a29a7f58c1b133d703 548 Gene3D G3DSA:3.30.565.10 296 461 5.6E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13965 8792331637eec0a29a7f58c1b133d703 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 4.2E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13965 8792331637eec0a29a7f58c1b133d703 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 451 4.2E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13965 8792331637eec0a29a7f58c1b133d703 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 393 4.2E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13965 8792331637eec0a29a7f58c1b133d703 548 SMART SM00387 338 454 1.6E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS07915 616c1c529591b3c5ddad04330e09022f 405 Gene3D G3DSA:1.10.287.470 144 190 7.5E-8 T 28-03-2018 MKLM6_RS07915 616c1c529591b3c5ddad04330e09022f 405 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 76 386 2.8E-61 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MKLM6_RS07915 616c1c529591b3c5ddad04330e09022f 405 SUPERFAMILY SSF111369 81 311 2.35E-32 T 28-03-2018 MKLM6_RS07915 616c1c529591b3c5ddad04330e09022f 405 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 91 306 2.5E-23 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MKLM6_RS07915 616c1c529591b3c5ddad04330e09022f 405 Gene3D G3DSA:2.40.50.100 89 143 2.2E-10 T 28-03-2018 MKLM6_RS07915 616c1c529591b3c5ddad04330e09022f 405 Gene3D G3DSA:2.40.50.100 191 363 3.3E-5 T 28-03-2018 MKLM6_RS20955 75db2c3282534fd82b39551b7de603ce 238 TIGRFAM TIGR03370 VPLPA-CTERM: VPLPA-CTERM protein sorting domain 210 234 3.6E-7 T 28-03-2018 IPR022472 VPLPA-CTERM protein sorting domain MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 SUPERFAMILY SSF55785 186 315 4.36E-20 T 28-03-2018 IPR000014 PAS domain MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 SMART SM00086 275 317 2.1E-6 T 28-03-2018 IPR001610 PAC motif MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 SMART SM00086 397 439 1.4E-5 T 28-03-2018 IPR001610 PAC motif MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 SMART SM00086 147 189 0.8 T 28-03-2018 IPR001610 PAC motif MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 SUPERFAMILY SSF55785 330 437 1.92E-25 T 28-03-2018 IPR000014 PAS domain MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 PIRSF PIRSF005925 315 443 4.6E-13 T 28-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 PIRSF PIRSF005925 437 873 8.8E-150 T 28-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 PIRSF PIRSF005925 224 326 10.0 T 28-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 SUPERFAMILY SSF55073 455 612 1.33E-52 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 Pfam PF00990 Diguanylate cyclase, GGDEF domain 450 606 4.2E-54 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 SMART SM00267 439 611 7.6E-74 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 SMART SM00052 621 867 4.5E-121 T 28-03-2018 IPR001633 EAL domain MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 Pfam PF08447 PAS fold 224 311 2.0E-20 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 Gene3D G3DSA:3.30.70.270 446 613 6.1E-64 T 28-03-2018 MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 SMART SM00091 64 130 19.0 T 28-03-2018 IPR000014 PAS domain MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 SMART SM00091 325 395 3.2E-4 T 28-03-2018 IPR000014 PAS domain MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 SMART SM00091 201 269 0.45 T 28-03-2018 IPR000014 PAS domain MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 448 609 1.4E-44 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 198 322 7.8E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 328 444 3.4E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 SUPERFAMILY SSF55785 52 187 3.32E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 SUPERFAMILY SSF141868 626 871 5.36E-92 T 28-03-2018 IPR001633 EAL domain MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 Gene3D G3DSA:3.40.50.10600 324 445 1.7E-25 T 28-03-2018 MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 Gene3D G3DSA:3.30.450.20 40 195 1.5E-19 T 28-03-2018 MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 Gene3D G3DSA:3.30.450.20 196 323 1.9E-27 T 28-03-2018 MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 Pfam PF13426 PAS domain 336 438 9.0E-11 T 28-03-2018 IPR000014 PAS domain MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 Gene3D G3DSA:3.20.20.450 614 870 3.8E-106 T 28-03-2018 IPR001633 EAL domain MKLM6_RS20175 941bbd6a94838434f1bbee76331a044a 874 Pfam PF00563 EAL domain 627 862 5.3E-77 T 28-03-2018 IPR001633 EAL domain MKLM6_RS21175 7e8d4e1f4977cbc0562a399833c66c4d 196 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 78 94 1.1E-6 T 28-03-2018 MKLM6_RS21175 7e8d4e1f4977cbc0562a399833c66c4d 196 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 48 62 1.1E-6 T 28-03-2018 MKLM6_RS21175 7e8d4e1f4977cbc0562a399833c66c4d 196 PRINTS PR00096 Glutamine amidotransferase superfamily signature 51 60 5.9E-14 T 28-03-2018 MKLM6_RS21175 7e8d4e1f4977cbc0562a399833c66c4d 196 PRINTS PR00096 Glutamine amidotransferase superfamily signature 78 89 5.9E-14 T 28-03-2018 MKLM6_RS21175 7e8d4e1f4977cbc0562a399833c66c4d 196 PRINTS PR00096 Glutamine amidotransferase superfamily signature 173 186 5.9E-14 T 28-03-2018 MKLM6_RS21175 7e8d4e1f4977cbc0562a399833c66c4d 196 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 6 196 2.5E-84 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MKLM6_RS21175 7e8d4e1f4977cbc0562a399833c66c4d 196 PRINTS PR00097 Anthranilate synthase component II signature 6 20 9.8E-37 T 28-03-2018 MKLM6_RS21175 7e8d4e1f4977cbc0562a399833c66c4d 196 PRINTS PR00097 Anthranilate synthase component II signature 173 186 9.8E-37 T 28-03-2018 MKLM6_RS21175 7e8d4e1f4977cbc0562a399833c66c4d 196 PRINTS PR00097 Anthranilate synthase component II signature 123 135 9.8E-37 T 28-03-2018 MKLM6_RS21175 7e8d4e1f4977cbc0562a399833c66c4d 196 PRINTS PR00097 Anthranilate synthase component II signature 103 111 9.8E-37 T 28-03-2018 MKLM6_RS21175 7e8d4e1f4977cbc0562a399833c66c4d 196 PRINTS PR00097 Anthranilate synthase component II signature 51 60 9.8E-37 T 28-03-2018 MKLM6_RS21175 7e8d4e1f4977cbc0562a399833c66c4d 196 PRINTS PR00097 Anthranilate synthase component II signature 78 89 9.8E-37 T 28-03-2018 MKLM6_RS21175 7e8d4e1f4977cbc0562a399833c66c4d 196 Pfam PF00117 Glutamine amidotransferase class-I 8 194 7.6E-56 T 28-03-2018 IPR017926 Glutamine amidotransferase MKLM6_RS21175 7e8d4e1f4977cbc0562a399833c66c4d 196 Gene3D G3DSA:3.40.50.880 4 196 9.6E-59 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS21175 7e8d4e1f4977cbc0562a399833c66c4d 196 SUPERFAMILY SSF52317 4 195 3.82E-57 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS10780 98fb7e24a13231b7aa565b18781aa460 868 SUPERFAMILY SSF56719 30 522 1.57E-182 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MKLM6_RS10780 98fb7e24a13231b7aa565b18781aa460 868 SMART SM00434 11 499 2.0E-287 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS10780 98fb7e24a13231b7aa565b18781aa460 868 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 506 3.3E-153 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS10780 98fb7e24a13231b7aa565b18781aa460 868 Gene3D G3DSA:3.90.199.10 287 376 2.4E-8 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS10780 98fb7e24a13231b7aa565b18781aa460 868 Gene3D G3DSA:1.10.268.10 377 497 2.4E-50 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS10780 98fb7e24a13231b7aa565b18781aa460 868 SUPERFAMILY SSF101904 533 852 4.19E-111 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal MKLM6_RS10780 98fb7e24a13231b7aa565b18781aa460 868 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 8 838 0.0 T 28-03-2018 MKLM6_RS10780 98fb7e24a13231b7aa565b18781aa460 868 Gene3D G3DSA:2.120.10.90 533 858 8.6E-133 T 28-03-2018 MKLM6_RS10780 98fb7e24a13231b7aa565b18781aa460 868 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 1 840 24.483 T 28-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS10780 98fb7e24a13231b7aa565b18781aa460 868 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 792 838 9.1E-13 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS10780 98fb7e24a13231b7aa565b18781aa460 868 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 645 688 1.2E-9 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS10780 98fb7e24a13231b7aa565b18781aa460 868 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 692 738 1.4E-13 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS10780 98fb7e24a13231b7aa565b18781aa460 868 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 588 637 5.1E-8 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS10780 98fb7e24a13231b7aa565b18781aa460 868 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 538 584 1.2E-9 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS10780 98fb7e24a13231b7aa565b18781aa460 868 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 746 789 9.9E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MKLM6_RS10780 98fb7e24a13231b7aa565b18781aa460 868 Gene3D G3DSA:3.90.199.10 34 286 3.2E-116 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 MKLM6_RS12865 bc2c2f24b83b8f6f22f2cc5b60d469d0 162 SUPERFAMILY SSF50475 3 158 1.72E-50 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MKLM6_RS12865 bc2c2f24b83b8f6f22f2cc5b60d469d0 162 Pfam PF01613 Flavin reductase like domain 16 158 5.1E-41 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 MKLM6_RS12865 bc2c2f24b83b8f6f22f2cc5b60d469d0 162 SMART SM00903 12 157 8.4E-60 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 MKLM6_RS12865 bc2c2f24b83b8f6f22f2cc5b60d469d0 162 Gene3D G3DSA:2.30.110.10 1 161 3.1E-48 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MKLM6_RS22465 8b449496e0e51bad6565aaba6d11222b 365 Pfam PF01609 Transposase DDE domain 199 346 5.6E-14 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS22465 8b449496e0e51bad6565aaba6d11222b 365 Pfam PF05598 Transposase domain (DUF772) 53 128 1.7E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS17475 8b449496e0e51bad6565aaba6d11222b 365 Pfam PF01609 Transposase DDE domain 199 346 5.6E-14 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS17475 8b449496e0e51bad6565aaba6d11222b 365 Pfam PF05598 Transposase domain (DUF772) 53 128 1.7E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS05420 8b449496e0e51bad6565aaba6d11222b 365 Pfam PF01609 Transposase DDE domain 199 346 5.6E-14 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS05420 8b449496e0e51bad6565aaba6d11222b 365 Pfam PF05598 Transposase domain (DUF772) 53 128 1.7E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS09285 8b449496e0e51bad6565aaba6d11222b 365 Pfam PF01609 Transposase DDE domain 199 346 5.6E-14 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS09285 8b449496e0e51bad6565aaba6d11222b 365 Pfam PF05598 Transposase domain (DUF772) 53 128 1.7E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS15565 ec0bb15b8eb797febe3de2b0a1e9d9a4 528 Pfam PF04262 Glutamate-cysteine ligase 13 385 7.1E-163 T 28-03-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MKLM6_RS15565 ec0bb15b8eb797febe3de2b0a1e9d9a4 528 Hamap MF_00578 Glutamate--cysteine ligase [gshA]. 1 528 206.168 T 28-03-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MKLM6_RS15565 ec0bb15b8eb797febe3de2b0a1e9d9a4 528 SUPERFAMILY SSF55931 12 521 4.32E-186 T 28-03-2018 MKLM6_RS15565 ec0bb15b8eb797febe3de2b0a1e9d9a4 528 TIGRFAM TIGR01434 glu_cys_ligase: glutamate--cysteine ligase 19 523 1.7E-184 T 28-03-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MKLM6_RS02850 d09d469ca84046a11aef93f10498e0db 374 Pfam PF13353 4Fe-4S single cluster domain 21 121 2.3E-7 T 28-03-2018 MKLM6_RS02850 d09d469ca84046a11aef93f10498e0db 374 TIGRFAM TIGR02109 PQQ_syn_pqqE: coenzyme PQQ biosynthesis enzyme PqqE 9 356 8.4E-168 T 28-03-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 MKLM6_RS02850 d09d469ca84046a11aef93f10498e0db 374 Hamap MF_00660 Coenzyme PQQ synthesis protein E [pqqE]. 1 374 182.668 T 28-03-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 MKLM6_RS02850 d09d469ca84046a11aef93f10498e0db 374 Pfam PF13186 Iron-sulfur cluster-binding domain 242 308 2.7E-8 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain MKLM6_RS02850 d09d469ca84046a11aef93f10498e0db 374 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 19 30 - T 28-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 MKLM6_RS02850 d09d469ca84046a11aef93f10498e0db 374 Gene3D G3DSA:3.20.20.70 7 316 2.6E-49 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS02850 d09d469ca84046a11aef93f10498e0db 374 SUPERFAMILY SSF102114 10 317 2.62E-80 T 28-03-2018 MKLM6_RS02850 d09d469ca84046a11aef93f10498e0db 374 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 242 335 3.7E-9 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain MKLM6_RS02850 d09d469ca84046a11aef93f10498e0db 374 PIRSF PIRSF037420 1 357 4.0E-127 T 28-03-2018 MKLM6_RS02850 d09d469ca84046a11aef93f10498e0db 374 Pfam PF04055 Radical SAM superfamily 21 173 3.8E-25 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS02850 d09d469ca84046a11aef93f10498e0db 374 SMART SM00729 13 215 3.1E-6 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MKLM6_RS03615 df03c8c4a2bc46b98c6d6910e041f000 215 SMART SM00448 10 121 2.9E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS03615 df03c8c4a2bc46b98c6d6910e041f000 215 SMART SM00421 145 202 2.1E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS03615 df03c8c4a2bc46b98c6d6910e041f000 215 Gene3D G3DSA:3.40.50.2300 7 149 5.9E-30 T 28-03-2018 MKLM6_RS03615 df03c8c4a2bc46b98c6d6910e041f000 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 4.3E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS03615 df03c8c4a2bc46b98c6d6910e041f000 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 4.3E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS03615 df03c8c4a2bc46b98c6d6910e041f000 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 4.3E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS03615 df03c8c4a2bc46b98c6d6910e041f000 215 SUPERFAMILY SSF52172 10 159 5.83E-32 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS03615 df03c8c4a2bc46b98c6d6910e041f000 215 SUPERFAMILY SSF46894 140 203 1.19E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MKLM6_RS03615 df03c8c4a2bc46b98c6d6910e041f000 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 202 5.6E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS03615 df03c8c4a2bc46b98c6d6910e041f000 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS03615 df03c8c4a2bc46b98c6d6910e041f000 215 Pfam PF00072 Response regulator receiver domain 12 121 2.6E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS03615 df03c8c4a2bc46b98c6d6910e041f000 215 Gene3D G3DSA:1.10.10.10 150 207 1.4E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS13870 3b88ae43200209e7bc8558e115983637 631 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 93 99 - T 28-03-2018 IPR014762 DNA mismatch repair, conserved site MKLM6_RS13870 3b88ae43200209e7bc8558e115983637 631 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 212 329 1.7E-38 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 MKLM6_RS13870 3b88ae43200209e7bc8558e115983637 631 SUPERFAMILY SSF118116 440 629 4.58E-59 T 28-03-2018 MKLM6_RS13870 3b88ae43200209e7bc8558e115983637 631 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 24 130 1.5E-11 T 28-03-2018 MKLM6_RS13870 3b88ae43200209e7bc8558e115983637 631 Gene3D G3DSA:3.30.230.10 205 328 6.7E-29 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MKLM6_RS13870 3b88ae43200209e7bc8558e115983637 631 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 1 310 1.2E-100 T 28-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 MKLM6_RS13870 3b88ae43200209e7bc8558e115983637 631 SMART SM00853 444 587 6.9E-48 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 MKLM6_RS13870 3b88ae43200209e7bc8558e115983637 631 SUPERFAMILY SSF55874 1 204 3.14E-52 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13870 3b88ae43200209e7bc8558e115983637 631 Pfam PF08676 MutL C terminal dimerisation domain 440 587 5.9E-48 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 MKLM6_RS13870 3b88ae43200209e7bc8558e115983637 631 Gene3D G3DSA:3.30.565.10 1 204 1.7E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13870 3b88ae43200209e7bc8558e115983637 631 SMART SM01340 212 330 1.3E-58 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 MKLM6_RS13870 3b88ae43200209e7bc8558e115983637 631 SUPERFAMILY SSF54211 191 330 1.97E-38 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS13870 3b88ae43200209e7bc8558e115983637 631 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 1 627 28.996 T 28-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 MKLM6_RS03265 6bdd51479566ed8de72d765fa1d82acc 298 SUPERFAMILY SSF55112 1 144 1.15E-63 T 28-03-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like domain MKLM6_RS03265 6bdd51479566ed8de72d765fa1d82acc 298 PIRSF PIRSF006414 1 298 6.0E-119 T 28-03-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 MKLM6_RS03265 6bdd51479566ed8de72d765fa1d82acc 298 TIGRFAM TIGR03119 one_C_fhcD: formylmethanofuran--tetrahydromethanopterin N-formyltransferase 8 296 3.9E-140 T 28-03-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 MKLM6_RS03265 6bdd51479566ed8de72d765fa1d82acc 298 Gene3D G3DSA:3.30.70.520 158 296 1.4E-62 T 28-03-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like domain MKLM6_RS03265 6bdd51479566ed8de72d765fa1d82acc 298 Gene3D G3DSA:3.30.70.520 19 157 3.1E-66 T 28-03-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like domain MKLM6_RS03265 6bdd51479566ed8de72d765fa1d82acc 298 Hamap MF_00579 Formylmethanofuran--tetrahydromethanopterin formyltransferase [ftr]. 1 297 47.306 T 28-03-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 MKLM6_RS03265 6bdd51479566ed8de72d765fa1d82acc 298 SUPERFAMILY SSF55112 145 297 2.16E-61 T 28-03-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like domain MKLM6_RS03265 6bdd51479566ed8de72d765fa1d82acc 298 Pfam PF01913 Formylmethanofuran-tetrahydromethanopterin formyltransferase 1 143 1.8E-63 T 28-03-2018 IPR022667 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, N-terminal GO:0006730|GO:0016740 MKLM6_RS03265 6bdd51479566ed8de72d765fa1d82acc 298 Pfam PF02741 FTR, proximal lobe 146 296 7.7E-66 T 28-03-2018 IPR002770 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, C-terminal GO:0006730|GO:0016740 MKLM6_RS08640 77f2e43bb8121258ccf5d836caa78ce3 464 Gene3D G3DSA:3.20.20.20 103 348 2.8E-8 T 28-03-2018 MKLM6_RS08640 77f2e43bb8121258ccf5d836caa78ce3 464 SUPERFAMILY SSF51717 121 327 2.62E-25 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MKLM6_RS10335 37beafc25b07a4d8086d64f02f489926 624 Pfam PF08376 Nitrate and nitrite sensing 57 295 5.4E-48 T 28-03-2018 IPR013587 Nitrate/nitrite sensing protein MKLM6_RS10335 37beafc25b07a4d8086d64f02f489926 624 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 403 432 8.1E-22 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MKLM6_RS10335 37beafc25b07a4d8086d64f02f489926 624 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 480 507 8.1E-22 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MKLM6_RS10335 37beafc25b07a4d8086d64f02f489926 624 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 509 538 8.1E-22 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MKLM6_RS10335 37beafc25b07a4d8086d64f02f489926 624 SUPERFAMILY SSF58104 384 623 8.72E-50 T 28-03-2018 MKLM6_RS10335 37beafc25b07a4d8086d64f02f489926 624 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 449 588 1.1E-27 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS10335 37beafc25b07a4d8086d64f02f489926 624 Gene3D G3DSA:1.10.287.950 282 442 5.6E-13 T 28-03-2018 MKLM6_RS10335 37beafc25b07a4d8086d64f02f489926 624 Gene3D G3DSA:1.10.287.950 443 624 7.9E-37 T 28-03-2018 MKLM6_RS10335 37beafc25b07a4d8086d64f02f489926 624 SMART SM00283 389 622 1.7E-50 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS22565 8a57a536ae301d98c90a952dcadb22bf 442 Pfam PF03743 Bacterial conjugation TrbI-like protein 230 435 1.6E-33 T 28-03-2018 IPR005498 Type IV secretion system, VirB10 / TraB / TrbI MKLM6_RS22565 8a57a536ae301d98c90a952dcadb22bf 442 Gene3D G3DSA:1.20.1170.10 45 372 1.5E-4 T 28-03-2018 MKLM6_RS02995 34f839b1ed61a866bd5ff4e49780e744 190 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 6 190 4.3E-61 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MKLM6_RS02995 34f839b1ed61a866bd5ff4e49780e744 190 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 5 190 18.757 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MKLM6_RS02995 34f839b1ed61a866bd5ff4e49780e744 190 SMART SM01207 8 185 9.5E-84 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MKLM6_RS02995 34f839b1ed61a866bd5ff4e49780e744 190 Pfam PF02660 Glycerol-3-phosphate acyltransferase 9 184 7.9E-52 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MKLM6_RS04300 7971f44049188207e3f34c40ee50412d 176 Pfam PF14367 Domain of unknown function (DUF4411) 7 167 2.6E-42 T 28-03-2018 IPR016541 Uncharacterised conserved protein UCP008505 MKLM6_RS04300 7971f44049188207e3f34c40ee50412d 176 Gene3D G3DSA:3.40.50.1010 7 148 5.9E-8 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS04300 7971f44049188207e3f34c40ee50412d 176 SUPERFAMILY SSF88723 6 147 3.36E-6 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS10500 f014feb463a081181fa67b45b324aa85 334 Gene3D G3DSA:3.40.190.10 134 334 1.6E-45 T 28-03-2018 MKLM6_RS10500 f014feb463a081181fa67b45b324aa85 334 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 150 158 - T 28-03-2018 IPR034408 Sulphate/thiosulphate-binding site GO:1901681 MKLM6_RS10500 f014feb463a081181fa67b45b324aa85 334 Pfam PF13531 Bacterial extracellular solute-binding protein 46 284 1.5E-40 T 28-03-2018 MKLM6_RS10500 f014feb463a081181fa67b45b324aa85 334 Gene3D G3DSA:3.40.190.10 24 133 2.2E-24 T 28-03-2018 MKLM6_RS10500 f014feb463a081181fa67b45b324aa85 334 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 23 331 2.1E-137 T 28-03-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 MKLM6_RS10500 f014feb463a081181fa67b45b324aa85 334 SUPERFAMILY SSF53850 24 333 1.09E-86 T 28-03-2018 MKLM6_RS17150 38fdbd0fa4f31f6a89d45e7660563bdb 346 Pfam PF12833 Helix-turn-helix domain 263 337 5.2E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MKLM6_RS17150 38fdbd0fa4f31f6a89d45e7660563bdb 346 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 304 319 3.4E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MKLM6_RS17150 38fdbd0fa4f31f6a89d45e7660563bdb 346 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 319 335 3.4E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MKLM6_RS17150 38fdbd0fa4f31f6a89d45e7660563bdb 346 SUPERFAMILY SSF52317 27 217 3.36E-31 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS17150 38fdbd0fa4f31f6a89d45e7660563bdb 346 Gene3D G3DSA:1.10.10.60 293 346 1.7E-15 T 28-03-2018 MKLM6_RS17150 38fdbd0fa4f31f6a89d45e7660563bdb 346 Pfam PF01965 DJ-1/PfpI family 31 155 5.6E-10 T 28-03-2018 IPR002818 DJ-1/PfpI MKLM6_RS17150 38fdbd0fa4f31f6a89d45e7660563bdb 346 SMART SM00342 252 335 2.3E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MKLM6_RS17150 38fdbd0fa4f31f6a89d45e7660563bdb 346 Gene3D G3DSA:3.40.50.880 10 252 7.3E-40 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS17150 38fdbd0fa4f31f6a89d45e7660563bdb 346 SUPERFAMILY SSF46689 288 339 4.48E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS17150 38fdbd0fa4f31f6a89d45e7660563bdb 346 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 289 331 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MKLM6_RS17150 38fdbd0fa4f31f6a89d45e7660563bdb 346 Gene3D G3DSA:1.10.10.60 253 292 1.4E-5 T 28-03-2018 MKLM6_RS09345 1236943fd799be84620057546f6dfd94 698 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 377 397 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 MKLM6_RS09345 1236943fd799be84620057546f6dfd94 698 TIGRFAM TIGR03904 SAM_YgiQ: uncharacterized radical SAM protein YgiQ 25 641 1.6E-258 T 28-03-2018 IPR022946 Uncharacterised protein family UPF0313 MKLM6_RS09345 1236943fd799be84620057546f6dfd94 698 Gene3D G3DSA:3.20.20.70 303 698 8.9E-33 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS09345 1236943fd799be84620057546f6dfd94 698 Gene3D G3DSA:3.40.50.280 42 213 0.027 T 28-03-2018 MKLM6_RS09345 1236943fd799be84620057546f6dfd94 698 SMART SM00729 373 620 8.6E-5 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MKLM6_RS09345 1236943fd799be84620057546f6dfd94 698 Pfam PF08497 Radical SAM N-terminal 25 376 1.1E-142 T 28-03-2018 IPR013704 Uncharacterised protein family UPF0313, N-terminal MKLM6_RS09345 1236943fd799be84620057546f6dfd94 698 Pfam PF11842 Domain of unknown function (DUF3362) 591 691 2.1E-47 T 28-03-2018 IPR024560 Uncharacterised protein family UPF0313, C-terminal MKLM6_RS09345 1236943fd799be84620057546f6dfd94 698 Hamap MF_01251 UPF0313 protein YgiQ [ygiQ]. 24 643 48.687 T 28-03-2018 IPR022946 Uncharacterised protein family UPF0313 MKLM6_RS09345 1236943fd799be84620057546f6dfd94 698 Pfam PF04055 Radical SAM superfamily 378 582 3.6E-20 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS09345 1236943fd799be84620057546f6dfd94 698 SUPERFAMILY SSF102114 470 645 4.32E-10 T 28-03-2018 MKLM6_RS09345 1236943fd799be84620057546f6dfd94 698 SUPERFAMILY SSF102114 377 440 4.32E-10 T 28-03-2018 MKLM6_RS19530 ecbe1529d3f859c776c881ddb323a11b 88 SUPERFAMILY SSF47336 19 86 4.89E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS19530 ecbe1529d3f859c776c881ddb323a11b 88 Gene3D G3DSA:1.10.1200.10 1 87 1.9E-7 T 28-03-2018 MKLM6_RS02080 c1ee95ff089f0dcb79d0ad0e6d57595e 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 5.5E-28 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS02080 c1ee95ff089f0dcb79d0ad0e6d57595e 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 21.399 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS02080 c1ee95ff089f0dcb79d0ad0e6d57595e 78 Pfam PF00830 Ribosomal L28 family 3 62 1.3E-26 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS02080 c1ee95ff089f0dcb79d0ad0e6d57595e 78 Gene3D G3DSA:2.30.170.40 2 75 2.1E-29 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS02080 c1ee95ff089f0dcb79d0ad0e6d57595e 78 SUPERFAMILY SSF143800 2 76 1.12E-30 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS15815 833114219744b89935c1709c13fb9625 356 TIGRFAM TIGR04421 FemAB_IMCC1989: FemAB family protein 25 352 1.1E-91 T 28-03-2018 IPR030952 FemAB family protein MKLM6_RS15815 833114219744b89935c1709c13fb9625 356 SUPERFAMILY SSF55729 183 349 2.7E-13 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS15815 833114219744b89935c1709c13fb9625 356 Gene3D G3DSA:3.40.630.30 142 348 1.5E-16 T 28-03-2018 MKLM6_RS19730 406289c1c1cc766cc28a64549a9dc8de 294 Pfam PF07603 Protein of unknown function (DUF1566) 83 255 3.0E-15 T 28-03-2018 IPR011460 Protein of unknown function DUF1566 MKLM6_RS15210 5c225420efea4d98876eb54fa52939db 354 SUPERFAMILY SSF55469 5 82 8.38E-8 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MKLM6_RS15210 5c225420efea4d98876eb54fa52939db 354 Gene3D G3DSA:3.40.109.10 87 341 3.0E-16 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MKLM6_RS15210 5c225420efea4d98876eb54fa52939db 354 SUPERFAMILY SSF55469 108 163 9.01E-9 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MKLM6_RS15210 5c225420efea4d98876eb54fa52939db 354 SUPERFAMILY SSF55469 237 351 9.01E-9 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MKLM6_RS15210 5c225420efea4d98876eb54fa52939db 354 Gene3D G3DSA:3.40.109.30 2 82 6.5E-7 T 28-03-2018 MKLM6_RS03015 c82bfb95d0408f6380d4782140ff42e7 580 TIGRFAM TIGR01391 dnaG: DNA primase 4 415 1.6E-133 T 28-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 MKLM6_RS03015 c82bfb95d0408f6380d4782140ff42e7 580 SMART SM00400 36 90 5.9E-33 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MKLM6_RS03015 c82bfb95d0408f6380d4782140ff42e7 580 Pfam PF08275 DNA primase catalytic core, N-terminal domain 128 247 2.8E-37 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal MKLM6_RS03015 c82bfb95d0408f6380d4782140ff42e7 580 SMART SM00493 257 328 1.5E-17 T 28-03-2018 IPR006171 TOPRIM domain MKLM6_RS03015 c82bfb95d0408f6380d4782140ff42e7 580 Gene3D G3DSA:1.10.860.10 439 580 2.0E-24 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal MKLM6_RS03015 c82bfb95d0408f6380d4782140ff42e7 580 Pfam PF10410 DnaB-helicase binding domain of primase 367 413 2.1E-4 T 28-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 MKLM6_RS03015 c82bfb95d0408f6380d4782140ff42e7 580 Gene3D G3DSA:3.40.1360.10 239 365 5.9E-31 T 28-03-2018 MKLM6_RS03015 c82bfb95d0408f6380d4782140ff42e7 580 Gene3D G3DSA:3.90.980.10 111 238 7.1E-42 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal MKLM6_RS03015 c82bfb95d0408f6380d4782140ff42e7 580 Pfam PF08278 DNA primase DnaG DnaB-binding 452 575 2.3E-22 T 28-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 MKLM6_RS03015 c82bfb95d0408f6380d4782140ff42e7 580 SUPERFAMILY SSF57783 4 100 9.35E-35 T 28-03-2018 MKLM6_RS03015 c82bfb95d0408f6380d4782140ff42e7 580 SUPERFAMILY SSF56731 118 416 6.28E-100 T 28-03-2018 MKLM6_RS03015 c82bfb95d0408f6380d4782140ff42e7 580 SUPERFAMILY SSF117023 448 578 4.32E-23 T 28-03-2018 MKLM6_RS03015 c82bfb95d0408f6380d4782140ff42e7 580 Gene3D G3DSA:3.90.580.10 1 102 3.9E-34 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MKLM6_RS03015 c82bfb95d0408f6380d4782140ff42e7 580 Hamap MF_00974 DNA primase [dnaG]. 4 577 28.385 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 MKLM6_RS03015 c82bfb95d0408f6380d4782140ff42e7 580 Pfam PF01807 CHC2 zinc finger 6 100 2.2E-37 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MKLM6_RS03015 c82bfb95d0408f6380d4782140ff42e7 580 Gene3D G3DSA:1.20.50.20 366 414 5.8E-15 T 28-03-2018 MKLM6_RS03015 c82bfb95d0408f6380d4782140ff42e7 580 PIRSF PIRSF002811 2 579 6.7E-138 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 MKLM6_RS03015 c82bfb95d0408f6380d4782140ff42e7 580 SMART SM00766 450 576 3.5E-20 T 28-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 MKLM6_RS03015 c82bfb95d0408f6380d4782140ff42e7 580 Pfam PF13155 Toprim-like 261 348 4.6E-15 T 28-03-2018 MKLM6_RS05890 82b8f0caf9f5402934d3d32489bc773f 486 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 370 482 4.9E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS05890 82b8f0caf9f5402934d3d32489bc773f 486 Gene3D G3DSA:3.30.565.10 320 484 8.8E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS05890 82b8f0caf9f5402934d3d32489bc773f 486 SUPERFAMILY SSF55874 314 482 4.71E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS05890 82b8f0caf9f5402934d3d32489bc773f 486 Pfam PF00512 His Kinase A (phospho-acceptor) domain 257 324 2.8E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS05890 82b8f0caf9f5402934d3d32489bc773f 486 Gene3D G3DSA:1.10.287.130 247 319 2.2E-10 T 28-03-2018 MKLM6_RS05890 82b8f0caf9f5402934d3d32489bc773f 486 SMART SM00388 257 325 4.5E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS05890 82b8f0caf9f5402934d3d32489bc773f 486 SMART SM00387 369 484 3.7E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS05890 82b8f0caf9f5402934d3d32489bc773f 486 SUPERFAMILY SSF47384 242 324 4.9E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS05890 82b8f0caf9f5402934d3d32489bc773f 486 SMART SM00304 204 256 0.0063 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS05890 82b8f0caf9f5402934d3d32489bc773f 486 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 420 1.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS05890 82b8f0caf9f5402934d3d32489bc773f 486 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 460 1.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS05890 82b8f0caf9f5402934d3d32489bc773f 486 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 434 1.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS05890 82b8f0caf9f5402934d3d32489bc773f 486 PRINTS PR00344 Bacterial sensor protein C-terminal signature 468 481 1.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS15260 2770ef050868b20e44b9db00df13ff3b 325 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 1 321 46.194 T 28-03-2018 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 MKLM6_RS15260 2770ef050868b20e44b9db00df13ff3b 325 Gene3D G3DSA:3.20.20.70 6 247 7.5E-54 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS15260 2770ef050868b20e44b9db00df13ff3b 325 SUPERFAMILY SSF51395 10 289 2.75E-81 T 28-03-2018 MKLM6_RS15260 2770ef050868b20e44b9db00df13ff3b 325 Pfam PF01207 Dihydrouridine synthase (Dus) 13 314 5.6E-105 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MKLM6_RS15260 2770ef050868b20e44b9db00df13ff3b 325 PIRSF PIRSF006621 1 320 3.1E-100 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MKLM6_RS15260 2770ef050868b20e44b9db00df13ff3b 325 Gene3D G3DSA:1.10.1200.80 250 324 8.8E-16 T 28-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 MKLM6_RS15260 2770ef050868b20e44b9db00df13ff3b 325 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 94 112 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 MKLM6_RS15260 2770ef050868b20e44b9db00df13ff3b 325 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 318 1.1E-117 T 28-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 MKLM6_RS09885 8686e7073f52697dbbc9065ac8f6a610 340 TIGRFAM TIGR02566 cas_Csy3: CRISPR type I-F/YPEST-associated protein Csy3 7 338 2.7E-124 T 28-03-2018 IPR013399 CRISPR-associated protein Csy3 MKLM6_RS09885 8686e7073f52697dbbc9065ac8f6a610 340 Pfam PF09615 CRISPR-associated protein (Cas_Csy3) 7 335 8.7E-143 T 28-03-2018 IPR013399 CRISPR-associated protein Csy3 MKLM6_RS12820 18fdb3a18b860fbfaa29541bd395ab21 259 SUPERFAMILY SSF53613 1 257 1.4E-63 T 28-03-2018 IPR029056 Ribokinase-like MKLM6_RS12820 18fdb3a18b860fbfaa29541bd395ab21 259 Gene3D G3DSA:3.40.1190.20 1 259 2.8E-49 T 28-03-2018 IPR029056 Ribokinase-like MKLM6_RS12820 18fdb3a18b860fbfaa29541bd395ab21 259 Pfam PF08543 Phosphomethylpyrimidine kinase 13 248 1.1E-71 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 MKLM6_RS06325 422f3fa20bf1f5586611cdf2de806027 377 SUPERFAMILY SSF53335 204 348 2.04E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS06325 422f3fa20bf1f5586611cdf2de806027 377 Pfam PF05175 Methyltransferase small domain 204 372 1.3E-53 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 MKLM6_RS06325 422f3fa20bf1f5586611cdf2de806027 377 Hamap MF_01859 Ribosomal RNA large subunit methyltransferase G [rlmG]. 2 376 46.447 T 28-03-2018 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MKLM6_RS06325 422f3fa20bf1f5586611cdf2de806027 377 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 305 311 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MKLM6_RS06325 422f3fa20bf1f5586611cdf2de806027 377 PIRSF PIRSF037565 1 377 2.0E-143 T 28-03-2018 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MKLM6_RS06325 422f3fa20bf1f5586611cdf2de806027 377 Gene3D G3DSA:3.40.50.150 34 183 0.2 T 28-03-2018 MKLM6_RS06325 422f3fa20bf1f5586611cdf2de806027 377 Gene3D G3DSA:3.40.50.150 193 377 1.1E-30 T 28-03-2018 MKLM6_RS03080 f084e30c32598fc27e8626035d29792c 424 Pfam PF11808 Domain of unknown function (DUF3329) 4 88 1.9E-19 T 28-03-2018 IPR021766 Protein of unknown function DUF3329 GO:0004673 MKLM6_RS03080 f084e30c32598fc27e8626035d29792c 424 Gene3D G3DSA:1.10.287.130 197 263 4.8E-18 T 28-03-2018 MKLM6_RS03080 f084e30c32598fc27e8626035d29792c 424 SUPERFAMILY SSF55874 256 420 1.31E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS03080 f084e30c32598fc27e8626035d29792c 424 SMART SM00387 309 422 5.4E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS03080 f084e30c32598fc27e8626035d29792c 424 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 309 420 9.9E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS03080 f084e30c32598fc27e8626035d29792c 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 419 1.6E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS03080 f084e30c32598fc27e8626035d29792c 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 400 1.6E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS03080 f084e30c32598fc27e8626035d29792c 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 347 361 1.6E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS03080 f084e30c32598fc27e8626035d29792c 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 375 1.6E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS03080 f084e30c32598fc27e8626035d29792c 424 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 92 418 1.1E-119 T 28-03-2018 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 MKLM6_RS03080 f084e30c32598fc27e8626035d29792c 424 Gene3D G3DSA:3.30.450.20 77 196 1.7E-5 T 28-03-2018 MKLM6_RS03080 f084e30c32598fc27e8626035d29792c 424 Pfam PF00512 His Kinase A (phospho-acceptor) domain 201 266 1.5E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS03080 f084e30c32598fc27e8626035d29792c 424 SMART SM00388 201 267 2.0E-22 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS03080 f084e30c32598fc27e8626035d29792c 424 SUPERFAMILY SSF47384 188 267 9.42E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS03080 f084e30c32598fc27e8626035d29792c 424 Gene3D G3DSA:3.30.565.10 281 423 2.8E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS03190 d7783948caea5a29a05d6bce979f0040 297 TIGRFAM TIGR00761 argB: acetylglutamate kinase 27 271 5.7E-74 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MKLM6_RS03190 d7783948caea5a29a05d6bce979f0040 297 SUPERFAMILY SSF53633 6 295 2.49E-94 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MKLM6_RS03190 d7783948caea5a29a05d6bce979f0040 297 Gene3D G3DSA:3.40.1160.10 7 297 1.3E-72 T 28-03-2018 MKLM6_RS03190 d7783948caea5a29a05d6bce979f0040 297 PRINTS PR00474 Glutamate 5-kinase family signature 57 71 2.4E-7 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MKLM6_RS03190 d7783948caea5a29a05d6bce979f0040 297 PRINTS PR00474 Glutamate 5-kinase family signature 246 266 2.4E-7 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MKLM6_RS03190 d7783948caea5a29a05d6bce979f0040 297 PRINTS PR00474 Glutamate 5-kinase family signature 196 223 2.4E-7 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MKLM6_RS03190 d7783948caea5a29a05d6bce979f0040 297 Pfam PF00696 Amino acid kinase family 27 273 1.6E-41 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MKLM6_RS03190 d7783948caea5a29a05d6bce979f0040 297 Hamap MF_00082_B Acetylglutamate kinase [argB]. 24 296 36.758 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MKLM6_RS03190 d7783948caea5a29a05d6bce979f0040 297 PIRSF PIRSF000728 11 296 1.4E-105 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MKLM6_RS07755 34179ff9f91f1e32e4d734bb54ca8698 155 Gene3D G3DSA:2.40.50.140 1 122 3.8E-44 T 28-03-2018 MKLM6_RS07755 34179ff9f91f1e32e4d734bb54ca8698 155 SUPERFAMILY SSF50249 1 155 2.23E-59 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS07755 34179ff9f91f1e32e4d734bb54ca8698 155 Pfam PF00436 Single-strand binding protein family 2 106 2.6E-41 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 MKLM6_RS07755 34179ff9f91f1e32e4d734bb54ca8698 155 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 155 3.4E-53 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MKLM6_RS07755 34179ff9f91f1e32e4d734bb54ca8698 155 Hamap MF_00984 Single-stranded DNA-binding protein. 2 110 38.626 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MKLM6_RS04775 b0b7640d21cd31bd64f80907e35e627c 742 SUPERFAMILY SSF103473 16 413 2.09E-6 T 28-03-2018 IPR020846 Major facilitator superfamily domain MKLM6_RS04775 b0b7640d21cd31bd64f80907e35e627c 742 SUPERFAMILY SSF53335 544 670 2.49E-21 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS04775 b0b7640d21cd31bd64f80907e35e627c 742 Gene3D G3DSA:1.20.1250.20 9 216 1.1E-5 T 28-03-2018 MKLM6_RS04775 b0b7640d21cd31bd64f80907e35e627c 742 Gene3D G3DSA:3.40.50.150 492 722 2.2E-12 T 28-03-2018 MKLM6_RS00045 49a6bd27d93da14f6845e38e0f5d410b 471 Gene3D G3DSA:1.20.1600.10 17 470 2.1E-96 T 28-03-2018 MKLM6_RS00045 49a6bd27d93da14f6845e38e0f5d410b 471 SUPERFAMILY SSF56954 4 28 1.7E-103 T 28-03-2018 MKLM6_RS00045 49a6bd27d93da14f6845e38e0f5d410b 471 SUPERFAMILY SSF56954 56 466 1.7E-103 T 28-03-2018 MKLM6_RS00045 49a6bd27d93da14f6845e38e0f5d410b 471 Pfam PF02321 Outer membrane efflux protein 279 459 3.9E-20 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS00045 49a6bd27d93da14f6845e38e0f5d410b 471 Pfam PF02321 Outer membrane efflux protein 65 252 4.3E-30 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS00045 49a6bd27d93da14f6845e38e0f5d410b 471 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 14 464 9.4E-101 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 MKLM6_RS14090 f4aaa3d2947356b217e4c8e34e947e5c 320 Pfam PF13673 Acetyltransferase (GNAT) domain 43 141 6.1E-20 T 28-03-2018 IPR000182 GNAT domain GO:0008080 MKLM6_RS14090 f4aaa3d2947356b217e4c8e34e947e5c 320 Gene3D G3DSA:3.40.630.30 6 165 1.3E-36 T 28-03-2018 MKLM6_RS14090 f4aaa3d2947356b217e4c8e34e947e5c 320 SUPERFAMILY SSF55729 1 144 3.37E-39 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS17735 f18f3039915245b992849940245727c7 137 Gene3D G3DSA:3.40.50.1010 1 135 1.4E-24 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS17735 f18f3039915245b992849940245727c7 137 SUPERFAMILY SSF88723 1 134 5.89E-29 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS17735 f18f3039915245b992849940245727c7 137 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 132 11.426 T 28-03-2018 IPR022907 VapC family GO:0004540 MKLM6_RS17735 f18f3039915245b992849940245727c7 137 Pfam PF01850 PIN domain 3 126 3.3E-12 T 28-03-2018 IPR002716 PIN domain MKLM6_RS19410 717ac02faee5f77e19f11a1fdc1aa128 1199 Gene3D G3DSA:3.50.50.60 537 751 2.6E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS19410 717ac02faee5f77e19f11a1fdc1aa128 1199 SUPERFAMILY SSF51971 401 454 3.85E-17 T 28-03-2018 MKLM6_RS19410 717ac02faee5f77e19f11a1fdc1aa128 1199 SUPERFAMILY SSF51971 488 599 3.85E-17 T 28-03-2018 MKLM6_RS19410 717ac02faee5f77e19f11a1fdc1aa128 1199 SUPERFAMILY SSF51971 668 731 3.85E-17 T 28-03-2018 MKLM6_RS19410 717ac02faee5f77e19f11a1fdc1aa128 1199 SUPERFAMILY SSF52343 983 1160 1.23E-14 T 28-03-2018 MKLM6_RS19410 717ac02faee5f77e19f11a1fdc1aa128 1199 Gene3D G3DSA:1.10.1060.10 229 379 2.9E-17 T 28-03-2018 MKLM6_RS19410 717ac02faee5f77e19f11a1fdc1aa128 1199 Gene3D G3DSA:2.40.30.10 873 969 3.7E-6 T 28-03-2018 MKLM6_RS19410 717ac02faee5f77e19f11a1fdc1aa128 1199 Gene3D G3DSA:3.40.50.80 970 1112 9.6E-4 T 28-03-2018 MKLM6_RS19410 717ac02faee5f77e19f11a1fdc1aa128 1199 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 404 625 2.3E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS19410 717ac02faee5f77e19f11a1fdc1aa128 1199 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 578 596 6.0E-5 T 28-03-2018 MKLM6_RS19410 717ac02faee5f77e19f11a1fdc1aa128 1199 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 405 424 6.0E-5 T 28-03-2018 MKLM6_RS19410 717ac02faee5f77e19f11a1fdc1aa128 1199 SUPERFAMILY SSF63380 876 977 6.32E-10 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MKLM6_RS19410 717ac02faee5f77e19f11a1fdc1aa128 1199 Gene3D G3DSA:3.40.50.720 392 536 1.6E-7 T 28-03-2018 MKLM6_RS21520 65bce8163444670b149f8eb06855af0c 101 Pfam PF11582 Protein of unknown function (DUF3240) 6 100 7.9E-20 T 28-03-2018 IPR021634 Protein of unknown function DUF3240 MKLM6_RS21950 29e520fa83506130a9eb85f30d4394ac 160 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 19 132 2.3E-7 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MKLM6_RS21950 29e520fa83506130a9eb85f30d4394ac 160 SUPERFAMILY SSF54593 14 146 1.75E-32 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MKLM6_RS21950 29e520fa83506130a9eb85f30d4394ac 160 Gene3D G3DSA:3.10.180.10 11 149 1.0E-29 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MKLM6_RS03150 6131b2933aaa9c0972bc7b76fbe3fae5 112 Pfam PF03960 ArsC family 5 109 3.2E-19 T 28-03-2018 IPR006660 Arsenate reductase-like MKLM6_RS03150 6131b2933aaa9c0972bc7b76fbe3fae5 112 Gene3D G3DSA:3.40.30.10 2 112 1.8E-34 T 28-03-2018 MKLM6_RS03150 6131b2933aaa9c0972bc7b76fbe3fae5 112 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 4 109 4.9E-30 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR MKLM6_RS03150 6131b2933aaa9c0972bc7b76fbe3fae5 112 SUPERFAMILY SSF52833 1 109 1.28E-32 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS21605 30c21a35b9492ac8b1fbf2cb2feafa71 350 SMART SM00870 4 326 4.4E-12 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MKLM6_RS21605 30c21a35b9492ac8b1fbf2cb2feafa71 350 Pfam PF00710 Asparaginase, N-terminal 4 141 1.9E-25 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 MKLM6_RS21605 30c21a35b9492ac8b1fbf2cb2feafa71 350 Gene3D G3DSA:3.40.50.1170 2 161 5.4E-29 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 MKLM6_RS21605 30c21a35b9492ac8b1fbf2cb2feafa71 350 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 7 15 - T 28-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 MKLM6_RS21605 30c21a35b9492ac8b1fbf2cb2feafa71 350 PIRSF PIRSF001220 1 337 4.8E-32 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MKLM6_RS21605 30c21a35b9492ac8b1fbf2cb2feafa71 350 PIRSF PIRSF500176 1 335 9.8E-33 T 28-03-2018 MKLM6_RS21605 30c21a35b9492ac8b1fbf2cb2feafa71 350 Gene3D G3DSA:3.40.50.40 213 340 2.6E-9 T 28-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 MKLM6_RS21605 30c21a35b9492ac8b1fbf2cb2feafa71 350 SUPERFAMILY SSF53774 3 338 4.06E-42 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MKLM6_RS21605 30c21a35b9492ac8b1fbf2cb2feafa71 350 PRINTS PR00139 Asparaginase/glutaminase family signature 83 101 6.6E-9 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MKLM6_RS21605 30c21a35b9492ac8b1fbf2cb2feafa71 350 PRINTS PR00139 Asparaginase/glutaminase family signature 5 16 6.6E-9 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MKLM6_RS06335 e412f551eb9e08cb92dc20a5121c3308 255 SUPERFAMILY SSF56281 2 254 1.54E-69 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS06335 e412f551eb9e08cb92dc20a5121c3308 255 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 2 254 42.185 T 28-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 MKLM6_RS06335 e412f551eb9e08cb92dc20a5121c3308 255 Gene3D G3DSA:3.60.15.10 1 254 4.0E-65 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS06335 e412f551eb9e08cb92dc20a5121c3308 255 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 5 254 1.5E-97 T 28-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 MKLM6_RS06335 e412f551eb9e08cb92dc20a5121c3308 255 Pfam PF00753 Metallo-beta-lactamase superfamily 16 170 1.7E-19 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS06335 e412f551eb9e08cb92dc20a5121c3308 255 PIRSF PIRSF005457 1 254 3.9E-105 T 28-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 MKLM6_RS06335 e412f551eb9e08cb92dc20a5121c3308 255 SMART SM00849 12 170 4.3E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS06335 e412f551eb9e08cb92dc20a5121c3308 255 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 171 254 1.8E-24 T 28-03-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 MKLM6_RS05820 752e83f8380e6007a669394a904d107a 199 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 105 116 - T 28-03-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 MKLM6_RS05820 752e83f8380e6007a669394a904d107a 199 Gene3D G3DSA:2.40.70.10 79 187 4.5E-16 T 28-03-2018 IPR021109 Aspartic peptidase domain MKLM6_RS05820 752e83f8380e6007a669394a904d107a 199 Pfam PF13975 gag-polyprotein putative aspartyl protease 96 180 2.6E-19 T 28-03-2018 MKLM6_RS05820 752e83f8380e6007a669394a904d107a 199 SUPERFAMILY SSF50630 86 184 4.5E-17 T 28-03-2018 IPR021109 Aspartic peptidase domain MKLM6_RS05820 752e83f8380e6007a669394a904d107a 199 TIGRFAM TIGR02281 clan_AA_DTGA: clan AA aspartic protease, TIGR02281 family 82 194 2.8E-23 T 28-03-2018 IPR011969 Clan AA aspartic peptidase, C-terminal MKLM6_RS06630 de13d056c5223fee38452bc0f664911f 80 SUPERFAMILY SSF143880 1 78 1.31E-23 T 28-03-2018 IPR018841 Protein of unknown function DUF2442 MKLM6_RS06630 de13d056c5223fee38452bc0f664911f 80 Gene3D G3DSA:3.30.2020.10 1 79 1.4E-22 T 28-03-2018 IPR018841 Protein of unknown function DUF2442 MKLM6_RS06630 de13d056c5223fee38452bc0f664911f 80 Pfam PF10387 Protein of unknown function (DUF2442) 5 76 2.4E-17 T 28-03-2018 IPR018841 Protein of unknown function DUF2442 MKLM6_RS16685 dad8772b4eec90a926a5a200f3ad5c30 78 Gene3D G3DSA:1.10.1200.10 2 76 7.1E-6 T 28-03-2018 MKLM6_RS16685 dad8772b4eec90a926a5a200f3ad5c30 78 Pfam PF00550 Phosphopantetheine attachment site 12 71 1.4E-4 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS16685 dad8772b4eec90a926a5a200f3ad5c30 78 SUPERFAMILY SSF47336 9 74 1.73E-7 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS03855 0d83afb78e9d76fc5a782a984f419fda 213 SUPERFAMILY SSF56784 2 212 1.38E-36 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS03855 0d83afb78e9d76fc5a782a984f419fda 213 Gene3D G3DSA:1.10.150.210 16 65 2.8E-15 T 28-03-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 MKLM6_RS03855 0d83afb78e9d76fc5a782a984f419fda 213 Gene3D G3DSA:3.40.50.1000 66 212 8.8E-15 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS03855 0d83afb78e9d76fc5a782a984f419fda 213 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 5 173 5.3E-18 T 28-03-2018 MKLM6_RS03855 0d83afb78e9d76fc5a782a984f419fda 213 Pfam PF12710 haloacid dehalogenase-like hydrolase 6 173 5.7E-10 T 28-03-2018 MKLM6_RS19625 cfafd8ab132ef9705fc2b7a0758c3459 90 SUPERFAMILY SSF54975 2 90 3.71E-29 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MKLM6_RS19625 cfafd8ab132ef9705fc2b7a0758c3459 90 Gene3D G3DSA:3.30.70.100 1 90 5.3E-29 T 28-03-2018 MKLM6_RS19625 cfafd8ab132ef9705fc2b7a0758c3459 90 ProSitePatterns PS00151 Acylphosphatase signature 2. 33 49 - T 28-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MKLM6_RS19625 cfafd8ab132ef9705fc2b7a0758c3459 90 Pfam PF00708 Acylphosphatase 6 89 8.7E-28 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MKLM6_RS19625 cfafd8ab132ef9705fc2b7a0758c3459 90 ProSitePatterns PS00150 Acylphosphatase signature 1. 9 19 - T 28-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MKLM6_RS19315 6a6b18e8fab78843cf6f91357c985b64 113 Hamap MF_00213 Probable hydrogenase nickel incorporation protein HypA [hypA]. 1 113 24.26 T 28-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 MKLM6_RS19315 6a6b18e8fab78843cf6f91357c985b64 113 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 28-03-2018 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site MKLM6_RS19315 6a6b18e8fab78843cf6f91357c985b64 113 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 112 3.9E-33 T 28-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 MKLM6_RS19315 6a6b18e8fab78843cf6f91357c985b64 113 PIRSF PIRSF004761 1 113 2.7E-38 T 28-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 MKLM6_RS19315 6a6b18e8fab78843cf6f91357c985b64 113 TIGRFAM TIGR00100 hypA: hydrogenase nickel insertion protein HypA 1 113 1.1E-33 T 28-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 MKLM6_RS15360 95d26020a7638ecc961dd24ebabe709c 398 Gene3D G3DSA:3.40.50.2000 79 218 9.4E-6 T 28-03-2018 MKLM6_RS15360 95d26020a7638ecc961dd24ebabe709c 398 Gene3D G3DSA:3.40.50.2000 219 378 1.9E-20 T 28-03-2018 MKLM6_RS15360 95d26020a7638ecc961dd24ebabe709c 398 Pfam PF13692 Glycosyl transferases group 1 228 366 5.3E-30 T 28-03-2018 MKLM6_RS15360 95d26020a7638ecc961dd24ebabe709c 398 TIGRFAM TIGR03087 stp1: sugar transferase, PEP-CTERM/EpsH1 system associated 5 395 7.1E-163 T 28-03-2018 IPR017521 Sugar transferase, PEP-CTERM, Stp1 MKLM6_RS15360 95d26020a7638ecc961dd24ebabe709c 398 SUPERFAMILY SSF53756 14 395 1.02E-33 T 28-03-2018 MKLM6_RS19050 8a1a7f789b40a3ff5f580fc97c596e35 441 SUPERFAMILY SSF116734 3 199 2.94E-32 T 28-03-2018 MKLM6_RS19050 8a1a7f789b40a3ff5f580fc97c596e35 441 Pfam PF01420 Type I restriction modification DNA specificity domain 5 172 8.8E-13 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MKLM6_RS19050 8a1a7f789b40a3ff5f580fc97c596e35 441 Pfam PF01420 Type I restriction modification DNA specificity domain 205 382 1.0E-9 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MKLM6_RS19050 8a1a7f789b40a3ff5f580fc97c596e35 441 SUPERFAMILY SSF116734 205 415 6.38E-41 T 28-03-2018 MKLM6_RS19050 8a1a7f789b40a3ff5f580fc97c596e35 441 Gene3D G3DSA:1.10.287.1120 371 431 4.3E-11 T 28-03-2018 MKLM6_RS19050 8a1a7f789b40a3ff5f580fc97c596e35 441 Gene3D G3DSA:3.90.220.20 170 370 2.6E-35 T 28-03-2018 MKLM6_RS19050 8a1a7f789b40a3ff5f580fc97c596e35 441 Gene3D G3DSA:3.90.220.20 1 169 1.1E-30 T 28-03-2018 MKLM6_RS02675 46590fbcc67304a55072a0c5dbc7d0e3 215 Gene3D G3DSA:3.20.20.70 5 211 7.5E-37 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS02675 46590fbcc67304a55072a0c5dbc7d0e3 215 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 6 209 1.0E-84 T 28-03-2018 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 MKLM6_RS02675 46590fbcc67304a55072a0c5dbc7d0e3 215 SUPERFAMILY SSF51366 1 212 6.1E-43 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MKLM6_RS02675 46590fbcc67304a55072a0c5dbc7d0e3 215 SMART SM00934 5 206 1.2E-42 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MKLM6_RS02675 46590fbcc67304a55072a0c5dbc7d0e3 215 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 6 206 1.7E-29 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MKLM6_RS18370 72d1a100eca51e926803d056509c0ee8 131 ProSitePatterns PS00053 Ribosomal protein S8 signature. 101 118 - T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18370 72d1a100eca51e926803d056509c0ee8 131 Gene3D G3DSA:3.30.1370.30 2 70 3.6E-26 T 28-03-2018 MKLM6_RS18370 72d1a100eca51e926803d056509c0ee8 131 Gene3D G3DSA:3.30.1490.10 71 128 1.6E-19 T 28-03-2018 MKLM6_RS18370 72d1a100eca51e926803d056509c0ee8 131 Pfam PF00410 Ribosomal protein S8 5 130 9.4E-49 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18370 72d1a100eca51e926803d056509c0ee8 131 SUPERFAMILY SSF56047 2 130 8.5E-46 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18370 72d1a100eca51e926803d056509c0ee8 131 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 131 31.369 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS11910 8bfe8de6d1a47796af4dae6aab591e55 351 Gene3D G3DSA:3.50.50.60 1 165 6.2E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS11910 8bfe8de6d1a47796af4dae6aab591e55 351 SUPERFAMILY SSF54373 204 288 1.83E-8 T 28-03-2018 MKLM6_RS11910 8bfe8de6d1a47796af4dae6aab591e55 351 SUPERFAMILY SSF51971 2 216 6.36E-19 T 28-03-2018 MKLM6_RS11910 8bfe8de6d1a47796af4dae6aab591e55 351 SUPERFAMILY SSF51971 274 332 6.36E-19 T 28-03-2018 MKLM6_RS11910 8bfe8de6d1a47796af4dae6aab591e55 351 Gene3D G3DSA:3.30.9.10 173 288 1.2E-12 T 28-03-2018 MKLM6_RS11910 8bfe8de6d1a47796af4dae6aab591e55 351 Pfam PF01266 FAD dependent oxidoreductase 4 327 3.5E-21 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MKLM6_RS09280 2fc87a9b009bd72979e079e3874efdda 150 Pfam PF13565 Homeodomain-like domain 62 126 5.3E-9 T 28-03-2018 MKLM6_RS09280 2fc87a9b009bd72979e079e3874efdda 150 Gene3D G3DSA:1.10.10.10 5 97 5.2E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS09280 2fc87a9b009bd72979e079e3874efdda 150 SUPERFAMILY SSF46689 13 132 3.94E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS09395 4a6ec0d6eccd8194cd3b1a40462bdb3f 698 Pfam PF00271 Helicase conserved C-terminal domain 464 574 1.6E-18 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS09395 4a6ec0d6eccd8194cd3b1a40462bdb3f 698 Pfam PF12344 Ultra-violet resistance protein B 581 622 1.2E-19 T 28-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain MKLM6_RS09395 4a6ec0d6eccd8194cd3b1a40462bdb3f 698 Gene3D G3DSA:4.10.860.10 638 697 3.9E-16 T 28-03-2018 IPR001943 UVR domain GO:0005515 MKLM6_RS09395 4a6ec0d6eccd8194cd3b1a40462bdb3f 698 Gene3D G3DSA:3.40.50.300 444 618 2.2E-32 T 28-03-2018 MKLM6_RS09395 4a6ec0d6eccd8194cd3b1a40462bdb3f 698 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 35 692 0.0 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 MKLM6_RS09395 4a6ec0d6eccd8194cd3b1a40462bdb3f 698 Pfam PF02151 UvrB/uvrC motif 661 694 3.9E-10 T 28-03-2018 IPR001943 UVR domain GO:0005515 MKLM6_RS09395 4a6ec0d6eccd8194cd3b1a40462bdb3f 698 SMART SM00487 39 454 1.9E-26 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MKLM6_RS09395 4a6ec0d6eccd8194cd3b1a40462bdb3f 698 SUPERFAMILY SSF46600 648 694 3.14E-12 T 28-03-2018 IPR001943 UVR domain GO:0005515 MKLM6_RS09395 4a6ec0d6eccd8194cd3b1a40462bdb3f 698 Pfam PF04851 Type III restriction enzyme, res subunit 45 122 1.3E-7 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MKLM6_RS09395 4a6ec0d6eccd8194cd3b1a40462bdb3f 698 SMART SM00490 489 575 6.1E-21 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS09395 4a6ec0d6eccd8194cd3b1a40462bdb3f 698 Hamap MF_00204 UvrABC system protein B [uvrB]. 33 695 43.196 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 MKLM6_RS09395 4a6ec0d6eccd8194cd3b1a40462bdb3f 698 SUPERFAMILY SSF52540 64 110 1.13E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS09395 4a6ec0d6eccd8194cd3b1a40462bdb3f 698 SUPERFAMILY SSF52540 499 620 1.13E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS09395 4a6ec0d6eccd8194cd3b1a40462bdb3f 698 Gene3D G3DSA:3.40.50.300 41 442 1.0E-31 T 28-03-2018 MKLM6_RS09395 4a6ec0d6eccd8194cd3b1a40462bdb3f 698 SUPERFAMILY SSF52540 33 444 4.5E-134 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS14950 e287c711c16869c7736fcaab9f405dcc 467 ProSitePatterns PS01219 Ammonium transporters signature. 213 238 - T 28-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 MKLM6_RS14950 e287c711c16869c7736fcaab9f405dcc 467 Gene3D G3DSA:1.10.3430.10 29 446 2.6E-127 T 28-03-2018 MKLM6_RS14950 e287c711c16869c7736fcaab9f405dcc 467 TIGRFAM TIGR00836 amt: ammonium transporter 37 465 7.3E-127 T 28-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 MKLM6_RS14950 e287c711c16869c7736fcaab9f405dcc 467 SUPERFAMILY SSF111352 33 446 1.27E-122 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 MKLM6_RS14950 e287c711c16869c7736fcaab9f405dcc 467 Pfam PF00909 Ammonium Transporter Family 39 465 6.1E-110 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 MKLM6_RS12150 041e13a8be9ab00ea0b3862bfb846839 490 Pfam PF09609 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) 11 480 2.0E-16 T 28-03-2018 IPR019089 CRISPR-associated protein, GSU0054 MKLM6_RS12150 041e13a8be9ab00ea0b3862bfb846839 490 TIGRFAM TIGR02165 cas5_6_GSU0054: CRISPR-associated protein GSU0054/csb2, Dpsyc system 1 481 4.1E-81 T 28-03-2018 IPR019089 CRISPR-associated protein, GSU0054 MKLM6_RS06795 a0eb02b385b4ec3d9c44b8f966d0d96e 433 Gene3D G3DSA:3.40.50.2300 166 318 3.4E-26 T 28-03-2018 MKLM6_RS06795 a0eb02b385b4ec3d9c44b8f966d0d96e 433 SUPERFAMILY SSF53822 33 405 7.5E-90 T 28-03-2018 IPR028082 Periplasmic binding protein-like I MKLM6_RS06795 a0eb02b385b4ec3d9c44b8f966d0d96e 433 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 34 399 1.2E-173 T 28-03-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like MKLM6_RS06795 a0eb02b385b4ec3d9c44b8f966d0d96e 433 Pfam PF13433 Periplasmic binding protein domain 34 402 5.5E-173 T 28-03-2018 MKLM6_RS06795 a0eb02b385b4ec3d9c44b8f966d0d96e 433 Gene3D G3DSA:3.40.50.2300 29 165 3.4E-22 T 28-03-2018 MKLM6_RS18810 a48a310e1ab114af55034c34f08d4596 237 Pfam PF02107 Flagellar L-ring protein 51 236 4.4E-59 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 MKLM6_RS18810 a48a310e1ab114af55034c34f08d4596 237 PRINTS PR01008 Flagellar L-ring protein signature 150 165 3.2E-24 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 MKLM6_RS18810 a48a310e1ab114af55034c34f08d4596 237 PRINTS PR01008 Flagellar L-ring protein signature 197 211 3.2E-24 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 MKLM6_RS18810 a48a310e1ab114af55034c34f08d4596 237 PRINTS PR01008 Flagellar L-ring protein signature 73 85 3.2E-24 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 MKLM6_RS18810 a48a310e1ab114af55034c34f08d4596 237 PRINTS PR01008 Flagellar L-ring protein signature 213 227 3.2E-24 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 MKLM6_RS18810 a48a310e1ab114af55034c34f08d4596 237 PRINTS PR01008 Flagellar L-ring protein signature 176 192 3.2E-24 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 MKLM6_RS18810 a48a310e1ab114af55034c34f08d4596 237 Hamap MF_00415 Flagellar L-ring protein [flgH]. 7 234 26.684 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 MKLM6_RS12750 b09339c8c88f471947bb42f2f6a70709 292 SUPERFAMILY SSF109604 24 287 2.1E-53 T 28-03-2018 MKLM6_RS12750 b09339c8c88f471947bb42f2f6a70709 292 Gene3D G3DSA:1.10.3210.10 8 291 3.4E-47 T 28-03-2018 MKLM6_RS12750 b09339c8c88f471947bb42f2f6a70709 292 Pfam PF08668 HDOD domain 33 218 5.4E-41 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD MKLM6_RS08570 c6242e467180dbbf2be29ab9bbf53ae4 111 Pfam PF07411 Domain of unknown function (DUF1508) 64 108 1.1E-4 T 28-03-2018 IPR010879 Domain of unknown function DUF1508 MKLM6_RS08570 c6242e467180dbbf2be29ab9bbf53ae4 111 Gene3D G3DSA:3.30.160.160 57 99 0.2 T 28-03-2018 IPR010879 Domain of unknown function DUF1508 MKLM6_RS08570 c6242e467180dbbf2be29ab9bbf53ae4 111 Gene3D G3DSA:3.30.160.160 5 48 1.4E-6 T 28-03-2018 IPR010879 Domain of unknown function DUF1508 MKLM6_RS08570 c6242e467180dbbf2be29ab9bbf53ae4 111 SUPERFAMILY SSF160113 1 50 6.41E-10 T 28-03-2018 IPR010879 Domain of unknown function DUF1508 MKLM6_RS08570 c6242e467180dbbf2be29ab9bbf53ae4 111 SUPERFAMILY SSF160113 63 109 4.58E-6 T 28-03-2018 IPR010879 Domain of unknown function DUF1508 MKLM6_RS11125 debeb11219056ff77fd1d6242d55f292 414 SMART SM00852 188 325 3.2E-35 T 28-03-2018 IPR001453 MoaB/Mog domain MKLM6_RS11125 debeb11219056ff77fd1d6242d55f292 414 SUPERFAMILY SSF63882 12 183 2.88E-51 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MKLM6_RS11125 debeb11219056ff77fd1d6242d55f292 414 Gene3D G3DSA:3.90.105.10 32 70 1.9E-10 T 28-03-2018 MKLM6_RS11125 debeb11219056ff77fd1d6242d55f292 414 Pfam PF00994 Probable molybdopterin binding domain 190 323 8.4E-25 T 28-03-2018 IPR001453 MoaB/Mog domain MKLM6_RS11125 debeb11219056ff77fd1d6242d55f292 414 Gene3D G3DSA:2.170.190.11 71 149 3.4E-22 T 28-03-2018 MKLM6_RS11125 debeb11219056ff77fd1d6242d55f292 414 Gene3D G3DSA:2.40.340.10 336 408 1.0E-16 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MKLM6_RS11125 debeb11219056ff77fd1d6242d55f292 414 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 185 321 2.0E-30 T 28-03-2018 IPR001453 MoaB/Mog domain MKLM6_RS11125 debeb11219056ff77fd1d6242d55f292 414 Gene3D G3DSA:3.40.980.10 160 331 1.6E-49 T 28-03-2018 IPR001453 MoaB/Mog domain MKLM6_RS11125 debeb11219056ff77fd1d6242d55f292 414 SUPERFAMILY SSF53218 185 329 1.07E-41 T 28-03-2018 IPR001453 MoaB/Mog domain MKLM6_RS11125 debeb11219056ff77fd1d6242d55f292 414 Pfam PF03453 MoeA N-terminal region (domain I and II) 14 175 4.8E-39 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MKLM6_RS11125 debeb11219056ff77fd1d6242d55f292 414 SUPERFAMILY SSF63867 334 410 5.76E-19 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MKLM6_RS11125 debeb11219056ff77fd1d6242d55f292 414 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 261 294 - T 28-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 MKLM6_RS11125 debeb11219056ff77fd1d6242d55f292 414 Pfam PF03454 MoeA C-terminal region (domain IV) 339 410 3.3E-14 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MKLM6_RS00060 c54425cb56c713b800d8d81807008055 125 Gene3D G3DSA:3.90.840.10 2 119 2.7E-4 T 28-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 MKLM6_RS00780 c7056a00a9972c90cbaa88d7863c3367 159 Gene3D G3DSA:2.60.120.10 10 159 5.2E-26 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS00780 c7056a00a9972c90cbaa88d7863c3367 159 SUPERFAMILY SSF51182 25 144 1.97E-19 T 28-03-2018 IPR011051 RmlC-like cupin domain MKLM6_RS00780 c7056a00a9972c90cbaa88d7863c3367 159 Pfam PF07883 Cupin domain 53 124 3.4E-16 T 28-03-2018 IPR013096 Cupin 2, conserved barrel MKLM6_RS10480 92a460ed8fcaaea022cdfa33eb11690a 559 Pfam PF08479 POTRA domain, ShlB-type 64 139 3.9E-17 T 28-03-2018 IPR013686 Polypeptide-transport-associated, ShlB-type MKLM6_RS10480 92a460ed8fcaaea022cdfa33eb11690a 559 Gene3D G3DSA:3.10.20.310 68 139 8.0E-14 T 28-03-2018 MKLM6_RS10480 92a460ed8fcaaea022cdfa33eb11690a 559 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 203 522 5.0E-21 T 28-03-2018 IPR005565 Haemolysin activator HlyB, C-terminal MKLM6_RS10480 92a460ed8fcaaea022cdfa33eb11690a 559 Gene3D G3DSA:2.40.160.50 171 559 5.1E-42 T 28-03-2018 MKLM6_RS21210 92a460ed8fcaaea022cdfa33eb11690a 559 Pfam PF08479 POTRA domain, ShlB-type 64 139 3.9E-17 T 28-03-2018 IPR013686 Polypeptide-transport-associated, ShlB-type MKLM6_RS21210 92a460ed8fcaaea022cdfa33eb11690a 559 Gene3D G3DSA:3.10.20.310 68 139 8.0E-14 T 28-03-2018 MKLM6_RS21210 92a460ed8fcaaea022cdfa33eb11690a 559 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 203 522 5.0E-21 T 28-03-2018 IPR005565 Haemolysin activator HlyB, C-terminal MKLM6_RS21210 92a460ed8fcaaea022cdfa33eb11690a 559 Gene3D G3DSA:2.40.160.50 171 559 5.1E-42 T 28-03-2018 MKLM6_RS00675 47feeb1c73006109242243041117092c 164 SUPERFAMILY SSF55729 1 163 9.43E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS00675 47feeb1c73006109242243041117092c 164 Pfam PF00583 Acetyltransferase (GNAT) family 33 139 1.1E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 MKLM6_RS00675 47feeb1c73006109242243041117092c 164 Gene3D G3DSA:3.40.630.30 1 164 6.7E-33 T 28-03-2018 MKLM6_RS00400 5f4ae4c0e57aef1930d0869c37a410b0 213 Gene3D G3DSA:3.40.50.150 16 193 2.3E-16 T 28-03-2018 MKLM6_RS00400 5f4ae4c0e57aef1930d0869c37a410b0 213 TIGRFAM TIGR03840 TMPT_Se_Te: thiopurine S-methyltransferase, Se/Te detoxification family 4 210 6.6E-75 T 28-03-2018 IPR022474 Thiopurine S-methyltransferase, Se/Te detoxification GO:0008119|GO:0010038|GO:0032259 KEGG: 00983+2.1.1.67 MKLM6_RS00400 5f4ae4c0e57aef1930d0869c37a410b0 213 SUPERFAMILY SSF53335 1 191 3.55E-50 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS00400 5f4ae4c0e57aef1930d0869c37a410b0 213 Pfam PF05724 Thiopurine S-methyltransferase (TPMT) 1 192 7.4E-56 T 28-03-2018 IPR008854 TPMT family GO:0008757 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581 MKLM6_RS00400 5f4ae4c0e57aef1930d0869c37a410b0 213 Hamap MF_00812 Thiopurine S-methyltransferase [tpm]. 1 211 37.351 T 28-03-2018 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581 MKLM6_RS00400 5f4ae4c0e57aef1930d0869c37a410b0 213 PIRSF PIRSF023956 1 213 1.7E-76 T 28-03-2018 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581 MKLM6_RS00610 26294026075601c71912cc321168a35b 122 Pfam PF03899 ATP synthase I chain 12 107 3.0E-17 T 28-03-2018 IPR005598 ATP synthase protein I MKLM6_RS14415 2689c541fa2e9bf5a6e1d3ba778390f9 133 TIGRFAM TIGR02044 CueR: Cu(I)-responsive transcriptional regulator 1 126 2.4E-54 T 28-03-2018 IPR011789 Cu(I)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0005507|GO:0045893 MKLM6_RS14415 2689c541fa2e9bf5a6e1d3ba778390f9 133 Gene3D G3DSA:1.10.1660.10 1 55 4.0E-24 T 28-03-2018 MKLM6_RS14415 2689c541fa2e9bf5a6e1d3ba778390f9 133 Gene3D G3DSA:1.10.1660.10 56 130 1.5E-21 T 28-03-2018 MKLM6_RS14415 2689c541fa2e9bf5a6e1d3ba778390f9 133 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MKLM6_RS14415 2689c541fa2e9bf5a6e1d3ba778390f9 133 Pfam PF09278 MerR, DNA binding 45 108 7.5E-20 T 28-03-2018 IPR015358 Transcription regulator MerR, DNA binding MKLM6_RS14415 2689c541fa2e9bf5a6e1d3ba778390f9 133 SMART SM00422 1 70 1.9E-31 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MKLM6_RS14415 2689c541fa2e9bf5a6e1d3ba778390f9 133 SUPERFAMILY SSF46955 1 126 2.2E-38 T 28-03-2018 IPR009061 Putative DNA-binding domain MKLM6_RS14415 2689c541fa2e9bf5a6e1d3ba778390f9 133 Pfam PF00376 MerR family regulatory protein 2 39 8.4E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MKLM6_RS14415 2689c541fa2e9bf5a6e1d3ba778390f9 133 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.9E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MKLM6_RS14415 2689c541fa2e9bf5a6e1d3ba778390f9 133 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 2.9E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MKLM6_RS14415 2689c541fa2e9bf5a6e1d3ba778390f9 133 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.9E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MKLM6_RS15880 3e1f86db695d46a003b79904ab2645c6 294 Pfam PF00483 Nucleotidyl transferase 5 241 4.5E-72 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MKLM6_RS15880 3e1f86db695d46a003b79904ab2645c6 294 Gene3D G3DSA:3.90.550.10 5 293 1.4E-72 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS15880 3e1f86db695d46a003b79904ab2645c6 294 SUPERFAMILY SSF53448 4 289 1.8E-93 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS15880 3e1f86db695d46a003b79904ab2645c6 294 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 5 289 3.4E-161 T 28-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 MKLM6_RS19400 c392fc111b0870de8ebbfeaccb49db5a 485 PIRSF PIRSF006247 1 485 2.1E-160 T 28-03-2018 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 MKLM6_RS19400 c392fc111b0870de8ebbfeaccb49db5a 485 Pfam PF02386 Cation transport protein 305 479 2.7E-24 T 28-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 MKLM6_RS19400 c392fc111b0870de8ebbfeaccb49db5a 485 Pfam PF02386 Cation transport protein 39 267 1.1E-43 T 28-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 MKLM6_RS14945 552a1d780828a5405c7e12d168d37e50 112 SMART SM00938 4 105 2.2E-66 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MKLM6_RS14945 552a1d780828a5405c7e12d168d37e50 112 Gene3D G3DSA:3.30.70.120 1 109 1.6E-48 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MKLM6_RS14945 552a1d780828a5405c7e12d168d37e50 112 PRINTS PR00340 P-II protein signature 2 17 1.5E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MKLM6_RS14945 552a1d780828a5405c7e12d168d37e50 112 PRINTS PR00340 P-II protein signature 83 103 1.5E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MKLM6_RS14945 552a1d780828a5405c7e12d168d37e50 112 PRINTS PR00340 P-II protein signature 23 41 1.5E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MKLM6_RS14945 552a1d780828a5405c7e12d168d37e50 112 PRINTS PR00340 P-II protein signature 52 75 1.5E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MKLM6_RS14945 552a1d780828a5405c7e12d168d37e50 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 4.3E-43 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MKLM6_RS14945 552a1d780828a5405c7e12d168d37e50 112 SUPERFAMILY SSF54913 1 112 9.53E-46 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MKLM6_RS14945 552a1d780828a5405c7e12d168d37e50 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 28-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 MKLM6_RS14945 552a1d780828a5405c7e12d168d37e50 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 28-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 MKLM6_RS14945 552a1d780828a5405c7e12d168d37e50 112 PIRSF PIRSF039144 1 112 4.5E-54 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MKLM6_RS12830 ada14761be8fee89f28a3eb610c561dc 68 SUPERFAMILY SSF89807 5 68 1.03E-25 T 28-03-2018 IPR009923 Dodecin MKLM6_RS12830 ada14761be8fee89f28a3eb610c561dc 68 Pfam PF07311 Dodecin 5 68 1.1E-28 T 28-03-2018 IPR009923 Dodecin MKLM6_RS12830 ada14761be8fee89f28a3eb610c561dc 68 Gene3D G3DSA:3.30.1660.10 4 68 7.7E-30 T 28-03-2018 IPR025543 Dodecin-like MKLM6_RS21975 5995acc0d5197d491ae02bca66da0c55 425 Pfam PF00202 Aminotransferase class-III 33 396 9.1E-79 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MKLM6_RS21975 5995acc0d5197d491ae02bca66da0c55 425 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 4 424 5.2E-194 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 MKLM6_RS21975 5995acc0d5197d491ae02bca66da0c55 425 Gene3D G3DSA:3.40.640.10 181 304 4.2E-45 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS21975 5995acc0d5197d491ae02bca66da0c55 425 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 270 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MKLM6_RS21975 5995acc0d5197d491ae02bca66da0c55 425 Gene3D G3DSA:3.90.1150.10 1 180 2.7E-46 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS21975 5995acc0d5197d491ae02bca66da0c55 425 Gene3D G3DSA:3.90.1150.10 305 425 1.6E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS21975 5995acc0d5197d491ae02bca66da0c55 425 SUPERFAMILY SSF53383 2 424 1.25E-136 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS21975 5995acc0d5197d491ae02bca66da0c55 425 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 3 425 105.695 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 MKLM6_RS03665 f9672153fa7c783e6936a50fc5c27840 155 Gene3D G3DSA:3.10.450.50 11 155 3.1E-72 T 28-03-2018 MKLM6_RS03665 f9672153fa7c783e6936a50fc5c27840 155 SUPERFAMILY SSF54427 2 155 3.95E-80 T 28-03-2018 IPR032710 NTF2-like domain MKLM6_RS03665 f9672153fa7c783e6936a50fc5c27840 155 Pfam PF07080 Protein of unknown function (DUF1348) 8 137 6.6E-67 T 28-03-2018 IPR009783 Protein of unknown function DUF1348 MKLM6_RS20990 d680c79ab5b56a4318a86727437bd1bc 165 Pfam PF08281 Sigma-70, region 4 108 160 1.4E-16 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS20990 d680c79ab5b56a4318a86727437bd1bc 165 Pfam PF04542 Sigma-70 region 2 12 76 2.2E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS20990 d680c79ab5b56a4318a86727437bd1bc 165 Gene3D G3DSA:1.10.1740.10 4 72 3.2E-14 T 28-03-2018 MKLM6_RS20990 d680c79ab5b56a4318a86727437bd1bc 165 SUPERFAMILY SSF88946 3 74 3.37E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS20990 d680c79ab5b56a4318a86727437bd1bc 165 SUPERFAMILY SSF88659 86 160 3.55E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS20990 d680c79ab5b56a4318a86727437bd1bc 165 Gene3D G3DSA:1.10.10.10 73 160 3.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS20990 d680c79ab5b56a4318a86727437bd1bc 165 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 160 8.2E-21 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS00465 a42959fa8d33cfdcabd7cc9962683ef4 115 Pfam PF03960 ArsC family 6 113 1.5E-19 T 28-03-2018 IPR006660 Arsenate reductase-like MKLM6_RS00465 a42959fa8d33cfdcabd7cc9962683ef4 115 Gene3D G3DSA:3.40.30.10 1 115 2.8E-40 T 28-03-2018 MKLM6_RS00465 a42959fa8d33cfdcabd7cc9962683ef4 115 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 3 115 2.1E-47 T 28-03-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 MKLM6_RS00465 a42959fa8d33cfdcabd7cc9962683ef4 115 SUPERFAMILY SSF52833 2 115 2.64E-37 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS10805 7423084ff9bee973812049f49b9530db 439 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 11 426 2.4E-121 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MKLM6_RS10805 7423084ff9bee973812049f49b9530db 439 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 15 435 32.605 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MKLM6_RS10805 7423084ff9bee973812049f49b9530db 439 Gene3D G3DSA:3.65.10.10 227 439 7.2E-51 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MKLM6_RS10805 7423084ff9bee973812049f49b9530db 439 PIRSF PIRSF000505 6 438 5.2E-116 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MKLM6_RS10805 7423084ff9bee973812049f49b9530db 439 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 19 433 1.4E-127 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MKLM6_RS10805 7423084ff9bee973812049f49b9530db 439 Gene3D G3DSA:3.65.10.10 26 226 4.6E-50 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MKLM6_RS10805 7423084ff9bee973812049f49b9530db 439 ProSitePatterns PS00104 EPSP synthase signature 1. 94 108 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MKLM6_RS10805 7423084ff9bee973812049f49b9530db 439 SUPERFAMILY SSF55205 9 434 7.36E-131 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 MKLM6_RS10805 7423084ff9bee973812049f49b9530db 439 ProSitePatterns PS00885 EPSP synthase signature 2. 347 365 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MKLM6_RS01040 a5a668b11bb8fa85a191a32513b4e8d0 159 Gene3D G3DSA:3.10.50.40 44 159 1.9E-43 T 28-03-2018 MKLM6_RS01040 a5a668b11bb8fa85a191a32513b4e8d0 159 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 69 156 1.7E-27 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MKLM6_RS01040 a5a668b11bb8fa85a191a32513b4e8d0 159 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 29 61 2.0E-11 T 28-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 MKLM6_RS01040 a5a668b11bb8fa85a191a32513b4e8d0 159 SUPERFAMILY SSF54534 21 158 4.32E-51 T 28-03-2018 MKLM6_RS01040 a5a668b11bb8fa85a191a32513b4e8d0 159 Gene3D G3DSA:1.10.287.460 11 43 5.6E-7 T 28-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 MKLM6_RS22345 00033640faa21423554161ae012202ec 138 Gene3D G3DSA:3.40.50.1010 4 129 1.2E-15 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS22345 00033640faa21423554161ae012202ec 138 SUPERFAMILY SSF88723 6 124 7.85E-19 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS22345 00033640faa21423554161ae012202ec 138 Pfam PF01850 PIN domain 7 116 6.0E-13 T 28-03-2018 IPR002716 PIN domain MKLM6_RS21655 5857502523255dce4db4fffa74d84d5f 192 SUPERFAMILY SSF53335 8 171 1.07E-24 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS21655 5857502523255dce4db4fffa74d84d5f 192 Pfam PF13649 Methyltransferase domain 39 125 6.9E-10 T 28-03-2018 MKLM6_RS21655 5857502523255dce4db4fffa74d84d5f 192 Gene3D G3DSA:3.40.50.150 1 187 2.2E-20 T 28-03-2018 MKLM6_RS09160 961e78b9fef624dc6288d6bcaa4cb748 157 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 154 26.536 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 MKLM6_RS09160 961e78b9fef624dc6288d6bcaa4cb748 157 Hamap MF_00930 Transcription elongation factor GreB [greB]. 1 156 52.466 T 28-03-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 MKLM6_RS09160 961e78b9fef624dc6288d6bcaa4cb748 157 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 119 135 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 MKLM6_RS09160 961e78b9fef624dc6288d6bcaa4cb748 157 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 3 157 1.1E-78 T 28-03-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 MKLM6_RS09160 961e78b9fef624dc6288d6bcaa4cb748 157 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 MKLM6_RS09160 961e78b9fef624dc6288d6bcaa4cb748 157 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 81 155 2.1E-21 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MKLM6_RS09160 961e78b9fef624dc6288d6bcaa4cb748 157 Pfam PF03449 Transcription elongation factor, N-terminal 5 74 3.7E-27 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 MKLM6_RS09160 961e78b9fef624dc6288d6bcaa4cb748 157 SUPERFAMILY SSF46557 4 78 4.84E-28 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 MKLM6_RS09160 961e78b9fef624dc6288d6bcaa4cb748 157 PIRSF PIRSF006092 1 157 3.1E-44 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 MKLM6_RS09160 961e78b9fef624dc6288d6bcaa4cb748 157 Gene3D G3DSA:3.10.50.30 76 157 7.5E-21 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MKLM6_RS09160 961e78b9fef624dc6288d6bcaa4cb748 157 Gene3D G3DSA:1.10.287.180 3 75 8.1E-30 T 28-03-2018 MKLM6_RS09160 961e78b9fef624dc6288d6bcaa4cb748 157 SUPERFAMILY SSF54534 81 156 9.68E-19 T 28-03-2018 MKLM6_RS10080 b5c52dd866fa168786aabcc34660aa4f 1327 Gene3D G3DSA:3.40.50.410 49 704 8.9E-27 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS10080 b5c52dd866fa168786aabcc34660aa4f 1327 Pfam PF05567 Neisseria PilC beta-propeller domain 811 1147 4.8E-73 T 28-03-2018 IPR008707 PilC beta-propeller domain MKLM6_RS10080 b5c52dd866fa168786aabcc34660aa4f 1327 SUPERFAMILY SSF50998 855 1160 8.63E-6 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MKLM6_RS00960 75512b4c74a727f211f13a76b7a3f8a2 203 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 188 6.0E-61 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 MKLM6_RS00960 75512b4c74a727f211f13a76b7a3f8a2 203 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 191 29.455 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 MKLM6_RS00960 75512b4c74a727f211f13a76b7a3f8a2 203 Gene3D G3DSA:3.40.50.300 1 200 2.7E-45 T 28-03-2018 MKLM6_RS00960 75512b4c74a727f211f13a76b7a3f8a2 203 Pfam PF01121 Dephospho-CoA kinase 4 177 2.1E-67 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 MKLM6_RS00960 75512b4c74a727f211f13a76b7a3f8a2 203 SUPERFAMILY SSF52540 1 190 1.62E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS11350 79e5f1d9bb4dd32c088afded7cda133a 323 SUPERFAMILY SSF158544 100 197 4.71E-24 T 28-03-2018 MKLM6_RS11350 79e5f1d9bb4dd32c088afded7cda133a 323 PIRSF PIRSF002786 5 297 5.7E-37 T 28-03-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 MKLM6_RS11350 79e5f1d9bb4dd32c088afded7cda133a 323 Pfam PF03934 Type II secretion system (T2SS), protein K 37 262 9.7E-30 T 28-03-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 MKLM6_RS11350 79e5f1d9bb4dd32c088afded7cda133a 323 Gene3D G3DSA:1.10.40.60 65 200 8.9E-25 T 28-03-2018 MKLM6_RS16075 06a363095e092c4820ba53a611a69e54 158 Gene3D G3DSA:3.30.530.20 6 156 5.8E-16 T 28-03-2018 IPR023393 START-like domain MKLM6_RS16075 06a363095e092c4820ba53a611a69e54 158 SUPERFAMILY SSF55961 6 150 2.2E-20 T 28-03-2018 MKLM6_RS05070 3bc6251c6d17b94c636e215392251c66 253 Pfam PF00990 Diguanylate cyclase, GGDEF domain 98 252 2.8E-50 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS05070 3bc6251c6d17b94c636e215392251c66 253 SUPERFAMILY SSF55073 103 251 2.9E-45 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS05070 3bc6251c6d17b94c636e215392251c66 253 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 97 252 2.5E-44 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS05070 3bc6251c6d17b94c636e215392251c66 253 Gene3D G3DSA:3.30.70.270 101 253 9.8E-54 T 28-03-2018 MKLM6_RS05070 3bc6251c6d17b94c636e215392251c66 253 Gene3D G3DSA:1.10.10.10 45 100 0.0011 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS05070 3bc6251c6d17b94c636e215392251c66 253 SMART SM00267 87 253 8.6E-47 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS04980 c04191c569a5f2fe02d3f999cc802edf 107 Gene3D G3DSA:3.40.30.10 3 106 1.1E-27 T 28-03-2018 MKLM6_RS04980 c04191c569a5f2fe02d3f999cc802edf 107 SUPERFAMILY SSF52833 5 102 2.01E-27 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS04980 c04191c569a5f2fe02d3f999cc802edf 107 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 23 89 2.0E-6 T 28-03-2018 MKLM6_RS03805 692e6cb6459423c4f3a7f9db503a2537 371 SUPERFAMILY SSF53067 143 340 2.91E-24 T 28-03-2018 MKLM6_RS03805 692e6cb6459423c4f3a7f9db503a2537 371 SUPERFAMILY SSF53067 66 111 2.91E-24 T 28-03-2018 MKLM6_RS03805 692e6cb6459423c4f3a7f9db503a2537 371 SUPERFAMILY SSF53067 4 36 2.91E-24 T 28-03-2018 MKLM6_RS03805 692e6cb6459423c4f3a7f9db503a2537 371 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 3 366 40.599 T 28-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 MKLM6_RS03805 692e6cb6459423c4f3a7f9db503a2537 371 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 4 365 3.2E-143 T 28-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 MKLM6_RS03805 692e6cb6459423c4f3a7f9db503a2537 371 Gene3D G3DSA:3.30.420.40 217 369 8.4E-25 T 28-03-2018 MKLM6_RS03805 692e6cb6459423c4f3a7f9db503a2537 371 Gene3D G3DSA:3.30.420.40 2 180 1.9E-57 T 28-03-2018 MKLM6_RS18465 740a1081714c46be096367dae2ead86f 124 PIRSF PIRSF002133 1 124 1.3E-53 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18465 740a1081714c46be096367dae2ead86f 124 Pfam PF00164 Ribosomal protein S12/S23 12 123 2.7E-42 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18465 740a1081714c46be096367dae2ead86f 124 Gene3D G3DSA:2.40.50.140 1 124 3.1E-63 T 28-03-2018 MKLM6_RS18465 740a1081714c46be096367dae2ead86f 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18465 740a1081714c46be096367dae2ead86f 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 124 2.0E-69 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18465 740a1081714c46be096367dae2ead86f 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 4.5E-60 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18465 740a1081714c46be096367dae2ead86f 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 4.5E-60 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18465 740a1081714c46be096367dae2ead86f 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 4.5E-60 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18465 740a1081714c46be096367dae2ead86f 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 4.5E-60 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18465 740a1081714c46be096367dae2ead86f 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 4.5E-60 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18465 740a1081714c46be096367dae2ead86f 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 4.5E-60 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18465 740a1081714c46be096367dae2ead86f 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 38.973 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18465 740a1081714c46be096367dae2ead86f 124 SUPERFAMILY SSF50249 3 123 1.37E-50 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS12475 6191bb4a5b839ab670550d50c178f196 106 Pfam PF08770 Sulphur oxidation protein SoxZ 8 99 8.3E-29 T 28-03-2018 IPR014880 Sulphur oxidation protein SoxZ MKLM6_RS12475 6191bb4a5b839ab670550d50c178f196 106 TIGRFAM TIGR04490 SoxZ_true: thiosulfate oxidation carrier complex protein SoxZ 6 102 1.7E-31 T 28-03-2018 IPR030995 Thiosulfate oxidation carrier complex protein SoxZ MKLM6_RS12475 6191bb4a5b839ab670550d50c178f196 106 Gene3D G3DSA:2.60.40.10 4 102 7.8E-31 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS12475 6191bb4a5b839ab670550d50c178f196 106 SUPERFAMILY SSF81296 1 103 5.32E-27 T 28-03-2018 IPR014756 Immunoglobulin E-set MKLM6_RS04445 810ac4bbcebd874b229131f8ea199a64 75 TIGRFAM TIGR02449 TIGR02449: TIGR02449 family protein 11 75 1.9E-18 T 28-03-2018 IPR012662 Conserved hypothetical protein CHP02449 MKLM6_RS04445 810ac4bbcebd874b229131f8ea199a64 75 Gene3D G3DSA:1.20.5.400 7 74 2.4E-4 T 28-03-2018 MKLM6_RS00860 47dcd08fcad5beb1d8d1025b7c440c2c 199 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 3 40 2.0E-10 T 28-03-2018 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 MKLM6_RS00860 47dcd08fcad5beb1d8d1025b7c440c2c 199 Gene3D G3DSA:1.20.5.510 4 33 7.8E-14 T 28-03-2018 MKLM6_RS00860 47dcd08fcad5beb1d8d1025b7c440c2c 199 Pfam PF00355 Rieske [2Fe-2S] domain 113 179 5.9E-11 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MKLM6_RS00860 47dcd08fcad5beb1d8d1025b7c440c2c 199 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 9 191 7.2E-70 T 28-03-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 MKLM6_RS00860 47dcd08fcad5beb1d8d1025b7c440c2c 199 PRINTS PR00162 Rieske 2Fe-2S subunit signature 150 162 4.4E-7 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 MKLM6_RS00860 47dcd08fcad5beb1d8d1025b7c440c2c 199 PRINTS PR00162 Rieske 2Fe-2S subunit signature 119 130 4.4E-7 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 MKLM6_RS00860 47dcd08fcad5beb1d8d1025b7c440c2c 199 PRINTS PR00162 Rieske 2Fe-2S subunit signature 163 175 4.4E-7 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 MKLM6_RS00860 47dcd08fcad5beb1d8d1025b7c440c2c 199 Gene3D G3DSA:2.102.10.10 34 199 2.7E-45 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MKLM6_RS00860 47dcd08fcad5beb1d8d1025b7c440c2c 199 SUPERFAMILY SSF50022 30 190 3.01E-44 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MKLM6_RS08500 2523f02c3553b70d47dc3ec58de744ee 597 Gene3D G3DSA:3.40.50.300 342 597 1.6E-74 T 28-03-2018 MKLM6_RS08500 2523f02c3553b70d47dc3ec58de744ee 597 Gene3D G3DSA:1.20.1560.10 9 341 2.9E-64 T 28-03-2018 MKLM6_RS08500 2523f02c3553b70d47dc3ec58de744ee 597 Pfam PF00664 ABC transporter transmembrane region 30 308 8.4E-48 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MKLM6_RS08500 2523f02c3553b70d47dc3ec58de744ee 597 Pfam PF00005 ABC transporter 375 523 2.2E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS08500 2523f02c3553b70d47dc3ec58de744ee 597 ProSitePatterns PS00211 ABC transporters family signature. 495 509 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS08500 2523f02c3553b70d47dc3ec58de744ee 597 SUPERFAMILY SSF90123 18 334 1.83E-66 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MKLM6_RS08500 2523f02c3553b70d47dc3ec58de744ee 597 SMART SM00382 383 569 2.7E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS08500 2523f02c3553b70d47dc3ec58de744ee 597 SUPERFAMILY SSF52540 352 594 1.1E-88 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS02685 df7ea7d628e33873e78505884f158705 669 ProSitePatterns PS00802 Transketolase signature 2. 474 490 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MKLM6_RS02685 df7ea7d628e33873e78505884f158705 669 Gene3D G3DSA:3.40.50.970 371 547 5.3E-39 T 28-03-2018 MKLM6_RS02685 df7ea7d628e33873e78505884f158705 669 Gene3D G3DSA:3.40.50.920 548 668 5.6E-33 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MKLM6_RS02685 df7ea7d628e33873e78505884f158705 669 SUPERFAMILY SSF52518 351 532 1.79E-67 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS02685 df7ea7d628e33873e78505884f158705 669 SUPERFAMILY SSF52922 540 669 3.27E-43 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MKLM6_RS02685 df7ea7d628e33873e78505884f158705 669 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 4 340 1.6E-164 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MKLM6_RS02685 df7ea7d628e33873e78505884f158705 669 TIGRFAM TIGR00232 tktlase_bact: transketolase 6 668 0.0 T 28-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 MKLM6_RS02685 df7ea7d628e33873e78505884f158705 669 Pfam PF02780 Transketolase, C-terminal domain 553 661 2.7E-15 T 28-03-2018 IPR033248 Transketolase, C-terminal domain MKLM6_RS02685 df7ea7d628e33873e78505884f158705 669 ProSitePatterns PS00801 Transketolase signature 1. 12 32 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MKLM6_RS02685 df7ea7d628e33873e78505884f158705 669 SMART SM00861 361 532 1.6E-66 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MKLM6_RS02685 df7ea7d628e33873e78505884f158705 669 Pfam PF02779 Transketolase, pyrimidine binding domain 360 532 1.2E-45 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MKLM6_RS02685 df7ea7d628e33873e78505884f158705 669 Gene3D G3DSA:3.40.50.970 1 370 1.0E-121 T 28-03-2018 MKLM6_RS02685 df7ea7d628e33873e78505884f158705 669 SUPERFAMILY SSF52518 6 335 7.5E-117 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS06320 ad19e3a7e69ed06d7ef12d8796429e28 265 Gene3D G3DSA:3.20.20.140 1 264 8.8E-80 T 28-03-2018 MKLM6_RS06320 ad19e3a7e69ed06d7ef12d8796429e28 265 SUPERFAMILY SSF51556 1 259 1.7E-87 T 28-03-2018 IPR032466 Metal-dependent hydrolase MKLM6_RS06320 ad19e3a7e69ed06d7ef12d8796429e28 265 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 MKLM6_RS06320 ad19e3a7e69ed06d7ef12d8796429e28 265 Pfam PF01026 TatD related DNase 3 254 8.9E-72 T 28-03-2018 IPR001130 TatD family GO:0016788 MKLM6_RS06320 ad19e3a7e69ed06d7ef12d8796429e28 265 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 255 8.3E-81 T 28-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 MKLM6_RS06320 ad19e3a7e69ed06d7ef12d8796429e28 265 PIRSF PIRSF005902 1 258 3.1E-75 T 28-03-2018 IPR001130 TatD family GO:0016788 MKLM6_RS17365 327677fb58a784e6772e4562cb83a30a 215 Pfam PF07603 Protein of unknown function (DUF1566) 34 185 1.1E-9 T 28-03-2018 IPR011460 Protein of unknown function DUF1566 MKLM6_RS12870 ce67e930ac380540f463e3241511a440 498 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 9 497 5.6E-213 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MKLM6_RS12870 ce67e930ac380540f463e3241511a440 498 PIRSF PIRSF039101 1 498 1.6E-194 T 28-03-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MKLM6_RS12870 ce67e930ac380540f463e3241511a440 498 SUPERFAMILY SSF50249 6 148 1.86E-45 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS12870 ce67e930ac380540f463e3241511a440 498 Gene3D G3DSA:2.40.50.140 8 147 1.1E-38 T 28-03-2018 MKLM6_RS12870 ce67e930ac380540f463e3241511a440 498 SUPERFAMILY SSF55681 155 495 3.64E-121 T 28-03-2018 MKLM6_RS12870 ce67e930ac380540f463e3241511a440 498 Pfam PF00152 tRNA synthetases class II (D, K and N) 155 494 4.2E-81 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS12870 ce67e930ac380540f463e3241511a440 498 Gene3D G3DSA:3.30.930.10 149 494 4.4E-101 T 28-03-2018 MKLM6_RS12870 ce67e930ac380540f463e3241511a440 498 Pfam PF01336 OB-fold nucleic acid binding domain 61 139 2.0E-14 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MKLM6_RS12870 ce67e930ac380540f463e3241511a440 498 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 14 497 44.612 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MKLM6_RS12870 ce67e930ac380540f463e3241511a440 498 PRINTS PR00982 Lysyl-tRNA synthetase signature 255 272 1.8E-37 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MKLM6_RS12870 ce67e930ac380540f463e3241511a440 498 PRINTS PR00982 Lysyl-tRNA synthetase signature 379 395 1.8E-37 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MKLM6_RS12870 ce67e930ac380540f463e3241511a440 498 PRINTS PR00982 Lysyl-tRNA synthetase signature 237 250 1.8E-37 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MKLM6_RS12870 ce67e930ac380540f463e3241511a440 498 PRINTS PR00982 Lysyl-tRNA synthetase signature 208 224 1.8E-37 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MKLM6_RS12870 ce67e930ac380540f463e3241511a440 498 PRINTS PR00982 Lysyl-tRNA synthetase signature 192 202 1.8E-37 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MKLM6_RS12795 bd536f195889d394d10e30c0cb212fab 393 Gene3D G3DSA:3.50.50.60 2 196 7.0E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS12795 bd536f195889d394d10e30c0cb212fab 393 Gene3D G3DSA:1.10.8.260 270 321 1.4E-14 T 28-03-2018 IPR023166 HI0933 insert-like domain MKLM6_RS12795 bd536f195889d394d10e30c0cb212fab 393 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 346 368 3.1E-6 T 28-03-2018 MKLM6_RS12795 bd536f195889d394d10e30c0cb212fab 393 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 3.1E-6 T 28-03-2018 MKLM6_RS12795 bd536f195889d394d10e30c0cb212fab 393 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.1E-6 T 28-03-2018 MKLM6_RS12795 bd536f195889d394d10e30c0cb212fab 393 Gene3D G3DSA:2.40.30.10 197 269 1.3E-23 T 28-03-2018 MKLM6_RS12795 bd536f195889d394d10e30c0cb212fab 393 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 361 368 3.4E-8 T 28-03-2018 MKLM6_RS12795 bd536f195889d394d10e30c0cb212fab 393 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 165 3.4E-8 T 28-03-2018 MKLM6_RS12795 bd536f195889d394d10e30c0cb212fab 393 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 3.4E-8 T 28-03-2018 MKLM6_RS12795 bd536f195889d394d10e30c0cb212fab 393 Pfam PF03486 HI0933-like protein 5 391 2.5E-147 T 28-03-2018 MKLM6_RS12795 bd536f195889d394d10e30c0cb212fab 393 SUPERFAMILY SSF160996 191 339 2.22E-38 T 28-03-2018 MKLM6_RS12795 bd536f195889d394d10e30c0cb212fab 393 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 6 391 5.2E-125 T 28-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like MKLM6_RS12795 bd536f195889d394d10e30c0cb212fab 393 SUPERFAMILY SSF51905 1 189 8.11E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS12795 bd536f195889d394d10e30c0cb212fab 393 SUPERFAMILY SSF51905 336 393 8.11E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS12470 e5095c6debfa87c09c584bf43a7437b2 153 Pfam PF13501 Sulfur oxidation protein SoxY 48 150 3.4E-29 T 28-03-2018 IPR032711 Ig-like SoxY domain MKLM6_RS12470 e5095c6debfa87c09c584bf43a7437b2 153 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 4 25 4.3E-6 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal MKLM6_RS12470 e5095c6debfa87c09c584bf43a7437b2 153 PIRSF PIRSF010312 1 152 2.7E-34 T 28-03-2018 IPR016568 Sulphur oxidation, SoxY MKLM6_RS12470 e5095c6debfa87c09c584bf43a7437b2 153 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 30 0.0014 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal MKLM6_RS14700 ee100da1b9d89dd2be85924369f12eae 525 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 23 111 5.3E-11 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14700 ee100da1b9d89dd2be85924369f12eae 525 SMART SM00283 260 521 1.5E-67 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS14700 ee100da1b9d89dd2be85924369f12eae 525 Pfam PF08447 PAS fold 32 114 8.5E-15 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS14700 ee100da1b9d89dd2be85924369f12eae 525 Gene3D G3DSA:1.10.287.1060 215 298 0.012 T 28-03-2018 MKLM6_RS14700 ee100da1b9d89dd2be85924369f12eae 525 Gene3D G3DSA:3.40.50.10600 2 125 2.7E-25 T 28-03-2018 MKLM6_RS14700 ee100da1b9d89dd2be85924369f12eae 525 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 333 487 1.3E-40 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS14700 ee100da1b9d89dd2be85924369f12eae 525 SUPERFAMILY SSF58104 216 521 3.75E-69 T 28-03-2018 MKLM6_RS14700 ee100da1b9d89dd2be85924369f12eae 525 Gene3D G3DSA:1.10.287.950 299 524 2.3E-50 T 28-03-2018 MKLM6_RS14700 ee100da1b9d89dd2be85924369f12eae 525 SUPERFAMILY SSF55785 23 114 5.76E-24 T 28-03-2018 IPR000014 PAS domain MKLM6_RS19935 91a8620a8d5ace6a08a476893bc42691 272 SMART SM00382 36 224 8.7E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS19935 91a8620a8d5ace6a08a476893bc42691 272 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS19935 91a8620a8d5ace6a08a476893bc42691 272 Pfam PF00005 ABC transporter 28 175 4.9E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS19935 91a8620a8d5ace6a08a476893bc42691 272 Gene3D G3DSA:3.40.50.300 8 254 1.4E-62 T 28-03-2018 MKLM6_RS19935 91a8620a8d5ace6a08a476893bc42691 272 SUPERFAMILY SSF52540 11 241 2.66E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS15855 a07e9b46f0b252915c27e726e8133b8e 384 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 12 379 8.1E-112 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MKLM6_RS15855 a07e9b46f0b252915c27e726e8133b8e 384 PIRSF PIRSF000390 1 384 4.1E-106 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MKLM6_RS15855 a07e9b46f0b252915c27e726e8133b8e 384 Gene3D G3DSA:3.40.640.10 7 255 8.6E-50 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS15855 a07e9b46f0b252915c27e726e8133b8e 384 TIGRFAM TIGR03588 PseC: UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase 4 381 8.3E-173 T 28-03-2018 IPR020026 UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase MKLM6_RS15855 a07e9b46f0b252915c27e726e8133b8e 384 SUPERFAMILY SSF53383 4 382 2.67E-112 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS15855 a07e9b46f0b252915c27e726e8133b8e 384 Gene3D G3DSA:3.90.1150.10 256 384 2.7E-39 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS19605 5df559c6dfe6ccbd3c91a6c40dee4d60 364 SUPERFAMILY SSF159245 51 355 2.09E-65 T 28-03-2018 MKLM6_RS19605 5df559c6dfe6ccbd3c91a6c40dee4d60 364 Gene3D G3DSA:2.40.370.10 228 359 5.6E-35 T 28-03-2018 IPR023374 AttH-like domain MKLM6_RS19605 5df559c6dfe6ccbd3c91a6c40dee4d60 364 Gene3D G3DSA:2.40.370.10 54 227 1.5E-29 T 28-03-2018 IPR023374 AttH-like domain MKLM6_RS19605 5df559c6dfe6ccbd3c91a6c40dee4d60 364 Pfam PF07143 CrtC N-terminal lipocalin domain 67 224 1.0E-29 T 28-03-2018 IPR010791 AttH domain MKLM6_RS19605 5df559c6dfe6ccbd3c91a6c40dee4d60 364 Pfam PF17186 Lipocalin-like domain 230 354 7.6E-33 T 28-03-2018 MKLM6_RS21920 10146807caa19bd0220b01588a3ac4bd 345 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 341 2.1E-154 T 28-03-2018 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 MKLM6_RS21920 10146807caa19bd0220b01588a3ac4bd 345 Pfam PF00437 Type II/IV secretion system protein 12 266 1.3E-46 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 MKLM6_RS21920 10146807caa19bd0220b01588a3ac4bd 345 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 193 207 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 MKLM6_RS21920 10146807caa19bd0220b01588a3ac4bd 345 Gene3D G3DSA:3.30.450.90 1 100 9.9E-25 T 28-03-2018 MKLM6_RS21920 10146807caa19bd0220b01588a3ac4bd 345 SMART SM00382 122 229 0.0014 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS21920 10146807caa19bd0220b01588a3ac4bd 345 SUPERFAMILY SSF52540 5 334 4.37E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS21920 10146807caa19bd0220b01588a3ac4bd 345 Gene3D G3DSA:3.40.50.300 116 273 7.1E-28 T 28-03-2018 MKLM6_RS21920 10146807caa19bd0220b01588a3ac4bd 345 Gene3D G3DSA:3.40.50.300 274 345 1.3E-13 T 28-03-2018 MKLM6_RS04895 f0ebded07edce1198ce6817536f2e1d2 708 Pfam PF00593 TonB dependent receptor 255 704 1.1E-36 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS04895 f0ebded07edce1198ce6817536f2e1d2 708 Pfam PF07715 TonB-dependent Receptor Plug Domain 57 164 9.5E-21 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS04895 f0ebded07edce1198ce6817536f2e1d2 708 Gene3D G3DSA:2.170.130.10 31 171 3.2E-30 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS04895 f0ebded07edce1198ce6817536f2e1d2 708 Gene3D G3DSA:2.40.170.20 172 707 8.9E-61 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS04895 f0ebded07edce1198ce6817536f2e1d2 708 SUPERFAMILY SSF56935 50 706 2.18E-100 T 28-03-2018 MKLM6_RS14300 83af22ffd96b563fcfef1235308c4863 621 SUPERFAMILY SSF55781 26 164 1.32E-15 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS14300 83af22ffd96b563fcfef1235308c4863 621 Pfam PF02954 Bacterial regulatory protein, Fis family 572 615 8.4E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS14300 83af22ffd96b563fcfef1235308c4863 621 SUPERFAMILY SSF52540 309 547 3.06E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS14300 83af22ffd96b563fcfef1235308c4863 621 SUPERFAMILY SSF55785 158 278 1.17E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14300 83af22ffd96b563fcfef1235308c4863 621 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 396 411 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MKLM6_RS14300 83af22ffd96b563fcfef1235308c4863 621 Pfam PF13188 PAS domain 167 227 1.2E-6 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14300 83af22ffd96b563fcfef1235308c4863 621 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 334 347 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MKLM6_RS14300 83af22ffd96b563fcfef1235308c4863 621 SMART SM00382 330 474 2.9E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS14300 83af22ffd96b563fcfef1235308c4863 621 Pfam PF00158 Sigma-54 interaction domain 310 476 1.7E-73 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MKLM6_RS14300 83af22ffd96b563fcfef1235308c4863 621 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 165 285 7.6E-8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14300 83af22ffd96b563fcfef1235308c4863 621 Gene3D G3DSA:1.10.8.60 482 562 2.8E-23 T 28-03-2018 MKLM6_RS14300 83af22ffd96b563fcfef1235308c4863 621 Gene3D G3DSA:3.30.450.40 13 164 3.7E-14 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS14300 83af22ffd96b563fcfef1235308c4863 621 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 523 532 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site MKLM6_RS14300 83af22ffd96b563fcfef1235308c4863 621 SMART SM00065 23 163 0.0025 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS14300 83af22ffd96b563fcfef1235308c4863 621 Gene3D G3DSA:3.40.50.300 303 481 1.5E-28 T 28-03-2018 MKLM6_RS14300 83af22ffd96b563fcfef1235308c4863 621 Gene3D G3DSA:3.30.450.20 165 300 1.6E-19 T 28-03-2018 MKLM6_RS14300 83af22ffd96b563fcfef1235308c4863 621 Gene3D G3DSA:1.10.10.60 567 619 5.0E-11 T 28-03-2018 MKLM6_RS00245 fe232055662ab7342c393d182d51253c 437 Gene3D G3DSA:1.10.150.130 109 239 0.0046 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal MKLM6_RS00245 fe232055662ab7342c393d182d51253c 437 Pfam PF13356 Arm DNA-binding domain 6 94 1.1E-13 T 28-03-2018 IPR025166 Integrase, DNA-binding domain MKLM6_RS00245 fe232055662ab7342c393d182d51253c 437 SUPERFAMILY SSF56349 163 397 5.3E-33 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS00245 fe232055662ab7342c393d182d51253c 437 Pfam PF00589 Phage integrase family 265 397 5.3E-16 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS00245 fe232055662ab7342c393d182d51253c 437 Gene3D G3DSA:1.10.443.10 240 412 1.3E-27 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS09425 bbab11a89cc1c5682654bce9c5f9443e 325 PIRSF PIRSF000102 1 324 6.7E-61 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MKLM6_RS09425 bbab11a89cc1c5682654bce9c5f9443e 325 Gene3D G3DSA:3.90.110.10 156 323 3.7E-50 T 28-03-2018 MKLM6_RS09425 bbab11a89cc1c5682654bce9c5f9443e 325 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 155 167 - T 28-03-2018 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MKLM6_RS09425 bbab11a89cc1c5682654bce9c5f9443e 325 Gene3D G3DSA:3.40.50.720 6 155 6.1E-24 T 28-03-2018 MKLM6_RS09425 bbab11a89cc1c5682654bce9c5f9443e 325 SUPERFAMILY SSF51735 1 154 6.22E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS09425 bbab11a89cc1c5682654bce9c5f9443e 325 SUPERFAMILY SSF56327 156 325 1.22E-55 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 MKLM6_RS09425 bbab11a89cc1c5682654bce9c5f9443e 325 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 145 1.1E-30 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 MKLM6_RS09425 bbab11a89cc1c5682654bce9c5f9443e 325 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 156 322 2.7E-32 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 MKLM6_RS09425 bbab11a89cc1c5682654bce9c5f9443e 325 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 3 320 2.1E-140 T 28-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 MKLM6_RS09425 bbab11a89cc1c5682654bce9c5f9443e 325 Hamap MF_01517 Malate dehydrogenase [mdh]. 1 325 51.829 T 28-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 MKLM6_RS09460 473ee70f2b8238df8823622d965b3e57 269 PRINTS PR00164 ABC-2 type transport system membrane protein signature 182 201 3.5E-9 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MKLM6_RS09460 473ee70f2b8238df8823622d965b3e57 269 PRINTS PR00164 ABC-2 type transport system membrane protein signature 145 169 3.5E-9 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MKLM6_RS09460 473ee70f2b8238df8823622d965b3e57 269 PRINTS PR00164 ABC-2 type transport system membrane protein signature 28 49 3.5E-9 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MKLM6_RS09460 473ee70f2b8238df8823622d965b3e57 269 Pfam PF01061 ABC-2 type transporter 13 228 1.2E-29 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MKLM6_RS09460 473ee70f2b8238df8823622d965b3e57 269 PIRSF PIRSF006648 3 258 1.1E-33 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MKLM6_RS09460 473ee70f2b8238df8823622d965b3e57 269 TIGRFAM TIGR03861 phenyl_ABC_PedC: alcohol ABC transporter, permease protein 7 259 6.4E-121 T 28-03-2018 IPR022403 Alcohol ABC transporter, permease protein MKLM6_RS04635 42564db19310c4022b3372cc609d334e 360 SUPERFAMILY SSF52540 11 235 3.77E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS04635 42564db19310c4022b3372cc609d334e 360 Gene3D G3DSA:3.40.50.300 9 259 1.3E-53 T 28-03-2018 MKLM6_RS04635 42564db19310c4022b3372cc609d334e 360 SUPERFAMILY SSF50331 242 359 2.76E-19 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal MKLM6_RS04635 42564db19310c4022b3372cc609d334e 360 TIGRFAM TIGR02142 modC_ABC: molybdate ABC transporter, ATP-binding protein 7 358 4.7E-131 T 28-03-2018 IPR011868 Molybdate ABC transporter, ATP-binding protein GO:0005524|GO:0015098|GO:0015689|GO:0016020 MKLM6_RS04635 42564db19310c4022b3372cc609d334e 360 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS04635 42564db19310c4022b3372cc609d334e 360 Pfam PF03459 TOBE domain 297 358 1.1E-14 T 28-03-2018 IPR005116 Transport-associated OB, type 1 MKLM6_RS04635 42564db19310c4022b3372cc609d334e 360 SMART SM00382 27 214 3.1E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS04635 42564db19310c4022b3372cc609d334e 360 Gene3D G3DSA:2.40.50.100 274 357 7.3E-22 T 28-03-2018 MKLM6_RS04635 42564db19310c4022b3372cc609d334e 360 Pfam PF00005 ABC transporter 20 164 6.3E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS11405 6fcd2874da3ffb9b1d8a2525888e09b5 752 PRINTS PR00133 Glycosyl hydrolase family 3 signature 229 245 3.1E-19 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MKLM6_RS11405 6fcd2874da3ffb9b1d8a2525888e09b5 752 PRINTS PR00133 Glycosyl hydrolase family 3 signature 122 138 3.1E-19 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MKLM6_RS11405 6fcd2874da3ffb9b1d8a2525888e09b5 752 PRINTS PR00133 Glycosyl hydrolase family 3 signature 299 317 3.1E-19 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MKLM6_RS11405 6fcd2874da3ffb9b1d8a2525888e09b5 752 PRINTS PR00133 Glycosyl hydrolase family 3 signature 146 165 3.1E-19 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MKLM6_RS11405 6fcd2874da3ffb9b1d8a2525888e09b5 752 PRINTS PR00133 Glycosyl hydrolase family 3 signature 192 208 3.1E-19 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MKLM6_RS11405 6fcd2874da3ffb9b1d8a2525888e09b5 752 SUPERFAMILY SSF52279 418 642 1.07E-53 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 MKLM6_RS11405 6fcd2874da3ffb9b1d8a2525888e09b5 752 Gene3D G3DSA:3.20.20.300 30 410 4.0E-110 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MKLM6_RS11405 6fcd2874da3ffb9b1d8a2525888e09b5 752 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 418 639 4.6E-48 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 MKLM6_RS11405 6fcd2874da3ffb9b1d8a2525888e09b5 752 Pfam PF14310 Fibronectin type III-like domain 676 744 3.6E-22 T 28-03-2018 IPR026891 Fibronectin type III-like domain MKLM6_RS11405 6fcd2874da3ffb9b1d8a2525888e09b5 752 SMART SM01217 676 745 5.3E-31 T 28-03-2018 IPR026891 Fibronectin type III-like domain MKLM6_RS11405 6fcd2874da3ffb9b1d8a2525888e09b5 752 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 45 381 1.1E-69 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MKLM6_RS11405 6fcd2874da3ffb9b1d8a2525888e09b5 752 Gene3D G3DSA:2.60.40.10 640 750 1.2E-31 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS11405 6fcd2874da3ffb9b1d8a2525888e09b5 752 Gene3D G3DSA:3.40.50.1700 411 639 1.8E-67 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 MKLM6_RS11405 6fcd2874da3ffb9b1d8a2525888e09b5 752 SUPERFAMILY SSF51445 29 417 9.58E-108 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily MKLM6_RS21865 1766d2f865db31bda7f4b962620fb906 682 PRINTS PR01041 Methionyl-tRNA synthetase signature 40 54 1.8E-24 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MKLM6_RS21865 1766d2f865db31bda7f4b962620fb906 682 PRINTS PR01041 Methionyl-tRNA synthetase signature 381 392 1.8E-24 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MKLM6_RS21865 1766d2f865db31bda7f4b962620fb906 682 PRINTS PR01041 Methionyl-tRNA synthetase signature 288 303 1.8E-24 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MKLM6_RS21865 1766d2f865db31bda7f4b962620fb906 682 PRINTS PR01041 Methionyl-tRNA synthetase signature 88 99 1.8E-24 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MKLM6_RS21865 1766d2f865db31bda7f4b962620fb906 682 PRINTS PR01041 Methionyl-tRNA synthetase signature 249 260 1.8E-24 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MKLM6_RS21865 1766d2f865db31bda7f4b962620fb906 682 PRINTS PR01041 Methionyl-tRNA synthetase signature 8 21 1.8E-24 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MKLM6_RS21865 1766d2f865db31bda7f4b962620fb906 682 Gene3D G3DSA:3.40.50.620 249 368 2.5E-22 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS21865 1766d2f865db31bda7f4b962620fb906 682 Pfam PF01588 Putative tRNA binding domain 587 679 8.4E-26 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 MKLM6_RS21865 1766d2f865db31bda7f4b962620fb906 682 SUPERFAMILY SSF50249 577 681 4.65E-32 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS21865 1766d2f865db31bda7f4b962620fb906 682 Gene3D G3DSA:2.40.50.140 573 682 7.7E-29 T 28-03-2018 MKLM6_RS21865 1766d2f865db31bda7f4b962620fb906 682 Gene3D G3DSA:2.170.220.10 164 248 1.1E-19 T 28-03-2018 MKLM6_RS21865 1766d2f865db31bda7f4b962620fb906 682 Gene3D G3DSA:2.20.28.20 140 163 6.9E-15 T 28-03-2018 MKLM6_RS21865 1766d2f865db31bda7f4b962620fb906 682 SUPERFAMILY SSF47323 387 545 3.66E-41 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS21865 1766d2f865db31bda7f4b962620fb906 682 Pfam PF09334 tRNA synthetases class I (M) 6 393 7.7E-158 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS21865 1766d2f865db31bda7f4b962620fb906 682 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 13 24 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS21865 1766d2f865db31bda7f4b962620fb906 682 Hamap MF_00098 Methionine--tRNA ligase [metG]. 4 543 40.291 T 28-03-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MKLM6_RS21865 1766d2f865db31bda7f4b962620fb906 682 Gene3D G3DSA:1.10.730.10 370 532 1.5E-32 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS21865 1766d2f865db31bda7f4b962620fb906 682 Gene3D G3DSA:3.40.50.620 2 79 2.4E-21 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS21865 1766d2f865db31bda7f4b962620fb906 682 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 6 532 1.8E-176 T 28-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MKLM6_RS21865 1766d2f865db31bda7f4b962620fb906 682 SUPERFAMILY SSF52374 3 139 5.38E-102 T 28-03-2018 MKLM6_RS21865 1766d2f865db31bda7f4b962620fb906 682 SUPERFAMILY SSF52374 174 384 5.38E-102 T 28-03-2018 MKLM6_RS21865 1766d2f865db31bda7f4b962620fb906 682 SUPERFAMILY SSF57770 140 173 3.14E-11 T 28-03-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MKLM6_RS21865 1766d2f865db31bda7f4b962620fb906 682 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 555 682 2.3E-45 T 28-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MKLM6_RS14745 723f9386ca446674aef2f1e7aa71e9a2 194 Pfam PF07681 DoxX 19 103 4.2E-20 T 28-03-2018 IPR032808 DoxX family MKLM6_RS11465 259ae34baa6a55803057f1c4fb825b01 638 Pfam PF06097 Bacterial protein of unknown function (DUF945) 4 369 1.9E-24 T 28-03-2018 IPR010352 Protein of unknown function DUF945 MKLM6_RS11465 259ae34baa6a55803057f1c4fb825b01 638 Pfam PF07007 Lysozyme inhibitor LprI 563 636 3.7E-8 T 28-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal MKLM6_RS13455 0871efeddb8e4cf366f9c247889bce68 222 Pfam PF00072 Response regulator receiver domain 3 113 5.2E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS13455 0871efeddb8e4cf366f9c247889bce68 222 SUPERFAMILY SSF52172 1 182 4.84E-37 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS13455 0871efeddb8e4cf366f9c247889bce68 222 Gene3D G3DSA:3.40.50.2300 1 118 2.8E-34 T 28-03-2018 MKLM6_RS13455 0871efeddb8e4cf366f9c247889bce68 222 Gene3D G3DSA:1.10.10.10 119 222 6.6E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS13455 0871efeddb8e4cf366f9c247889bce68 222 SMART SM00448 1 113 9.9E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS13455 0871efeddb8e4cf366f9c247889bce68 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 219 1.9E-17 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS13455 0871efeddb8e4cf366f9c247889bce68 222 SMART SM00862 146 219 6.1E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS15440 e1cb359f4aa8abda4d9b4481321a5489 418 Gene3D G3DSA:3.10.180.10 348 405 0.02 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MKLM6_RS15440 e1cb359f4aa8abda4d9b4481321a5489 418 SUPERFAMILY SSF54593 75 389 7.79E-8 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MKLM6_RS15440 e1cb359f4aa8abda4d9b4481321a5489 418 Gene3D G3DSA:3.10.180.10 220 347 5.3E-5 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MKLM6_RS01555 72508f88a5affff85e0a32f206393c9a 321 Gene3D G3DSA:3.30.1380.10 199 321 6.3E-22 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MKLM6_RS01555 72508f88a5affff85e0a32f206393c9a 321 Pfam PF05951 Bacterial protein of unknown function (DUF882) 173 319 2.0E-52 T 28-03-2018 IPR010275 Protein of unknown function DUF882 MKLM6_RS01555 72508f88a5affff85e0a32f206393c9a 321 SUPERFAMILY SSF55166 203 320 5.1E-30 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MKLM6_RS03520 0c3bfd198adb41905ea6c32530e8f2f0 179 Gene3D G3DSA:3.90.1570.10 4 161 1.3E-29 T 28-03-2018 MKLM6_RS03520 0c3bfd198adb41905ea6c32530e8f2f0 179 Pfam PF05685 Putative restriction endonuclease 5 137 2.7E-21 T 28-03-2018 IPR008538 Domain of unknown function DUF820 MKLM6_RS03520 0c3bfd198adb41905ea6c32530e8f2f0 179 SUPERFAMILY SSF52980 11 153 3.65E-17 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MKLM6_RS14870 fffb06a61e30fdf416cb3080669ba324 393 Pfam PF16539 Flagellar assembly protein T, middle domain 110 268 8.3E-26 T 28-03-2018 IPR032386 Flagellar assembly protein T, middle domain MKLM6_RS19020 4b9144ee891adf92ebb7c8ca1c633e92 596 SMART SM00091 164 230 2.2E-4 T 28-03-2018 IPR000014 PAS domain MKLM6_RS19020 4b9144ee891adf92ebb7c8ca1c633e92 596 Gene3D G3DSA:3.30.565.10 440 591 1.3E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS19020 4b9144ee891adf92ebb7c8ca1c633e92 596 SMART SM00388 339 442 0.0061 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS19020 4b9144ee891adf92ebb7c8ca1c633e92 596 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 5 128 3.6E-32 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 MKLM6_RS19020 4b9144ee891adf92ebb7c8ca1c633e92 596 SUPERFAMILY SSF55785 156 276 3.66E-21 T 28-03-2018 IPR000014 PAS domain MKLM6_RS19020 4b9144ee891adf92ebb7c8ca1c633e92 596 Gene3D G3DSA:1.10.287.130 336 438 8.5E-13 T 28-03-2018 MKLM6_RS19020 4b9144ee891adf92ebb7c8ca1c633e92 596 Gene3D G3DSA:3.30.450.20 153 335 1.9E-31 T 28-03-2018 MKLM6_RS19020 4b9144ee891adf92ebb7c8ca1c633e92 596 Pfam PF08447 PAS fold 187 269 5.3E-13 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS19020 4b9144ee891adf92ebb7c8ca1c633e92 596 SUPERFAMILY SSF47188 1 128 1.2E-28 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 MKLM6_RS19020 4b9144ee891adf92ebb7c8ca1c633e92 596 SUPERFAMILY SSF47384 333 370 7.46E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS19020 4b9144ee891adf92ebb7c8ca1c633e92 596 SMART SM00387 482 591 3.9E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS19020 4b9144ee891adf92ebb7c8ca1c633e92 596 PRINTS PR00344 Bacterial sensor protein C-terminal signature 551 569 1.5E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS19020 4b9144ee891adf92ebb7c8ca1c633e92 596 PRINTS PR00344 Bacterial sensor protein C-terminal signature 520 534 1.5E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS19020 4b9144ee891adf92ebb7c8ca1c633e92 596 PRINTS PR00344 Bacterial sensor protein C-terminal signature 575 588 1.5E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS19020 4b9144ee891adf92ebb7c8ca1c633e92 596 PRINTS PR00344 Bacterial sensor protein C-terminal signature 538 548 1.5E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS19020 4b9144ee891adf92ebb7c8ca1c633e92 596 Pfam PF01814 Hemerythrin HHE cation binding domain 14 127 3.5E-13 T 28-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 MKLM6_RS19020 4b9144ee891adf92ebb7c8ca1c633e92 596 Gene3D G3DSA:1.20.120.50 1 134 6.2E-34 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 MKLM6_RS19020 4b9144ee891adf92ebb7c8ca1c633e92 596 SUPERFAMILY SSF55874 432 591 1.83E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS19020 4b9144ee891adf92ebb7c8ca1c633e92 596 Pfam PF00512 His Kinase A (phospho-acceptor) domain 340 441 4.9E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS19020 4b9144ee891adf92ebb7c8ca1c633e92 596 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 160 285 2.7E-13 T 28-03-2018 IPR000014 PAS domain MKLM6_RS19020 4b9144ee891adf92ebb7c8ca1c633e92 596 SMART SM00086 236 278 8.0E-4 T 28-03-2018 IPR001610 PAC motif MKLM6_RS19020 4b9144ee891adf92ebb7c8ca1c633e92 596 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 486 590 2.9E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS01180 78990e03255b99e94f0cbaee11962093 888 Pfam PF03176 MMPL family 55 434 4.6E-21 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MKLM6_RS01180 78990e03255b99e94f0cbaee11962093 888 Pfam PF03176 MMPL family 734 879 7.6E-6 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MKLM6_RS01180 78990e03255b99e94f0cbaee11962093 888 SUPERFAMILY SSF82866 243 436 7.85E-28 T 28-03-2018 MKLM6_RS01180 78990e03255b99e94f0cbaee11962093 888 Gene3D G3DSA:1.20.1640.10 687 884 7.7E-29 T 28-03-2018 MKLM6_RS01180 78990e03255b99e94f0cbaee11962093 888 SUPERFAMILY SSF82866 702 883 5.36E-31 T 28-03-2018 MKLM6_RS01180 78990e03255b99e94f0cbaee11962093 888 Gene3D G3DSA:1.20.1640.10 235 446 5.2E-31 T 28-03-2018 MKLM6_RS01180 78990e03255b99e94f0cbaee11962093 888 TIGRFAM TIGR03480 HpnN: hopanoid biosynthesis associated RND transporter like protein HpnN 12 880 2.3E-278 T 28-03-2018 IPR017841 Hopanoid biosynthesis associated RND transporter-like protein HpnN MKLM6_RS13620 0a7846a64e544dbe53a43cda5e577ad8 212 Gene3D G3DSA:2.30.30.410 15 97 1.2E-9 T 28-03-2018 MKLM6_RS13620 0a7846a64e544dbe53a43cda5e577ad8 212 TIGRFAM TIGR04211 SH3_and_anchor: SH3 domain protein 24 209 1.8E-54 T 28-03-2018 IPR016476 SH3 domain protein MKLM6_RS13620 0a7846a64e544dbe53a43cda5e577ad8 212 Pfam PF08239 Bacterial SH3 domain 31 83 2.8E-7 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type MKLM6_RS13620 0a7846a64e544dbe53a43cda5e577ad8 212 SMART SM00287 20 86 5.7E-5 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type MKLM6_RS10815 0bbcf3982162b0408792ccca16707788 219 Gene3D G3DSA:3.40.50.300 4 219 4.9E-41 T 28-03-2018 MKLM6_RS10815 0bbcf3982162b0408792ccca16707788 219 Hamap MF_00238 Cytidylate kinase [cmk]. 5 219 29.539 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MKLM6_RS10815 0bbcf3982162b0408792ccca16707788 219 TIGRFAM TIGR00017 cmk: cytidylate kinase 5 216 4.0E-70 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MKLM6_RS10815 0bbcf3982162b0408792ccca16707788 219 SUPERFAMILY SSF52540 5 218 5.09E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS10815 0bbcf3982162b0408792ccca16707788 219 Pfam PF02224 Cytidylate kinase 8 218 6.1E-68 T 28-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MKLM6_RS17925 cc6b0c6464ed11d7385415530a7b091b 383 Pfam PF13533 Biotin-lipoyl like 55 101 1.2E-15 T 28-03-2018 MKLM6_RS17925 cc6b0c6464ed11d7385415530a7b091b 383 SUPERFAMILY SSF111369 182 288 2.48E-8 T 28-03-2018 MKLM6_RS17925 cc6b0c6464ed11d7385415530a7b091b 383 Pfam PF13437 HlyD family secretion protein 238 318 6.8E-10 T 28-03-2018 MKLM6_RS17925 cc6b0c6464ed11d7385415530a7b091b 383 Gene3D G3DSA:1.20.1600.10 30 336 4.3E-22 T 28-03-2018 MKLM6_RS17925 cc6b0c6464ed11d7385415530a7b091b 383 SUPERFAMILY SSF111369 52 137 9.15E-15 T 28-03-2018 MKLM6_RS03710 5001f6f371d2526165f818b9816f7e72 340 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 7 337 4.3E-140 T 28-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MKLM6_RS03710 5001f6f371d2526165f818b9816f7e72 340 SUPERFAMILY SSF51735 5 159 2.78E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS03710 5001f6f371d2526165f818b9816f7e72 340 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 4 336 38.749 T 28-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MKLM6_RS03710 5001f6f371d2526165f818b9816f7e72 340 SMART SM00859 6 121 1.4E-46 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MKLM6_RS03710 5001f6f371d2526165f818b9816f7e72 340 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 7 120 2.6E-33 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MKLM6_RS03710 5001f6f371d2526165f818b9816f7e72 340 Gene3D G3DSA:3.40.50.720 1 143 2.6E-34 T 28-03-2018 MKLM6_RS03710 5001f6f371d2526165f818b9816f7e72 340 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 141 322 2.1E-62 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MKLM6_RS03710 5001f6f371d2526165f818b9816f7e72 340 PIRSF PIRSF000148 4 340 5.4E-136 T 28-03-2018 MKLM6_RS03710 5001f6f371d2526165f818b9816f7e72 340 SUPERFAMILY SSF55347 131 323 7.44E-78 T 28-03-2018 MKLM6_RS03710 5001f6f371d2526165f818b9816f7e72 340 Gene3D G3DSA:3.30.360.10 144 318 7.7E-75 T 28-03-2018 MKLM6_RS05525 b3681f9a3f5c8d65c27829d5749e3644 199 SUPERFAMILY SSF52218 1 198 2.64E-57 T 28-03-2018 IPR029039 Flavoprotein-like domain MKLM6_RS05525 b3681f9a3f5c8d65c27829d5749e3644 199 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 198 31.74 T 28-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 MKLM6_RS05525 b3681f9a3f5c8d65c27829d5749e3644 199 Pfam PF02525 Flavodoxin-like fold 1 196 3.0E-50 T 28-03-2018 IPR003680 Flavodoxin-like fold MKLM6_RS05525 b3681f9a3f5c8d65c27829d5749e3644 199 Gene3D G3DSA:3.40.50.360 1 199 1.7E-45 T 28-03-2018 IPR029039 Flavoprotein-like domain MKLM6_RS05530 08a826d225fada9ec3b19927dd911c55 294 Pfam PF05726 Pirin C-terminal cupin domain 186 289 6.1E-28 T 28-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 MKLM6_RS05530 08a826d225fada9ec3b19927dd911c55 294 PIRSF PIRSF006232 13 294 7.9E-98 T 28-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 MKLM6_RS05530 08a826d225fada9ec3b19927dd911c55 294 Gene3D G3DSA:2.60.120.10 11 262 7.8E-80 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS05530 08a826d225fada9ec3b19927dd911c55 294 SUPERFAMILY SSF51182 17 292 4.07E-87 T 28-03-2018 IPR011051 RmlC-like cupin domain MKLM6_RS05530 08a826d225fada9ec3b19927dd911c55 294 Pfam PF02678 Pirin 32 132 4.8E-35 T 28-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 MKLM6_RS03000 dd421bc3e25a45fff03968dc95a0be30 336 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 312 6.0E-133 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MKLM6_RS03000 dd421bc3e25a45fff03968dc95a0be30 336 ProSitePatterns PS01016 Glycoprotease family signature. 96 116 - T 28-03-2018 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 MKLM6_RS03000 dd421bc3e25a45fff03968dc95a0be30 336 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 305 8.1E-120 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MKLM6_RS03000 dd421bc3e25a45fff03968dc95a0be30 336 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 2.5E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MKLM6_RS03000 dd421bc3e25a45fff03968dc95a0be30 336 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 2.5E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MKLM6_RS03000 dd421bc3e25a45fff03968dc95a0be30 336 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 262 271 2.5E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MKLM6_RS03000 dd421bc3e25a45fff03968dc95a0be30 336 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 2.5E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MKLM6_RS03000 dd421bc3e25a45fff03968dc95a0be30 336 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 2.5E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MKLM6_RS03000 dd421bc3e25a45fff03968dc95a0be30 336 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 2.5E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MKLM6_RS03000 dd421bc3e25a45fff03968dc95a0be30 336 Pfam PF00814 Glycoprotease family 24 306 3.4E-102 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MKLM6_RS03000 dd421bc3e25a45fff03968dc95a0be30 336 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 330 62.91 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MKLM6_RS03000 dd421bc3e25a45fff03968dc95a0be30 336 Gene3D G3DSA:3.30.420.40 1 144 1.2E-38 T 28-03-2018 MKLM6_RS03000 dd421bc3e25a45fff03968dc95a0be30 336 SUPERFAMILY SSF53067 3 122 1.35E-30 T 28-03-2018 MKLM6_RS03000 dd421bc3e25a45fff03968dc95a0be30 336 Gene3D G3DSA:3.30.420.40 145 288 1.5E-19 T 28-03-2018 MKLM6_RS03000 dd421bc3e25a45fff03968dc95a0be30 336 SUPERFAMILY SSF53067 101 308 3.67E-44 T 28-03-2018 MKLM6_RS16925 3682c5761043723e6c3aac831089b920 281 SMART SM00880 12 266 6.2E-18 T 28-03-2018 IPR007899 CHAD domain MKLM6_RS16925 3682c5761043723e6c3aac831089b920 281 Pfam PF05235 CHAD domain 16 232 1.1E-26 T 28-03-2018 IPR007899 CHAD domain MKLM6_RS15920 0eb1a89b617de2ece6e88164674413b8 328 Pfam PF02371 Transposase IS116/IS110/IS902 family 201 285 2.1E-24 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 MKLM6_RS15920 0eb1a89b617de2ece6e88164674413b8 328 Pfam PF01548 Transposase 4 154 5.2E-25 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 MKLM6_RS15920 0eb1a89b617de2ece6e88164674413b8 328 Gene3D G3DSA:1.10.150.20 26 240 0.0012 T 28-03-2018 MKLM6_RS02040 0eb1a89b617de2ece6e88164674413b8 328 Pfam PF02371 Transposase IS116/IS110/IS902 family 201 285 2.1E-24 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 MKLM6_RS02040 0eb1a89b617de2ece6e88164674413b8 328 Pfam PF01548 Transposase 4 154 5.2E-25 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 MKLM6_RS02040 0eb1a89b617de2ece6e88164674413b8 328 Gene3D G3DSA:1.10.150.20 26 240 0.0012 T 28-03-2018 MKLM6_RS16025 0eb1a89b617de2ece6e88164674413b8 328 Pfam PF02371 Transposase IS116/IS110/IS902 family 201 285 2.1E-24 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 MKLM6_RS16025 0eb1a89b617de2ece6e88164674413b8 328 Pfam PF01548 Transposase 4 154 5.2E-25 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 MKLM6_RS16025 0eb1a89b617de2ece6e88164674413b8 328 Gene3D G3DSA:1.10.150.20 26 240 0.0012 T 28-03-2018 MKLM6_RS01520 0eb1a89b617de2ece6e88164674413b8 328 Pfam PF02371 Transposase IS116/IS110/IS902 family 201 285 2.1E-24 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 MKLM6_RS01520 0eb1a89b617de2ece6e88164674413b8 328 Pfam PF01548 Transposase 4 154 5.2E-25 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 MKLM6_RS01520 0eb1a89b617de2ece6e88164674413b8 328 Gene3D G3DSA:1.10.150.20 26 240 0.0012 T 28-03-2018 MKLM6_RS09165 8bd810264b3c19b0ed3f62da628bb3c0 158 SUPERFAMILY SSF54534 3 139 1.81E-37 T 28-03-2018 MKLM6_RS09165 8bd810264b3c19b0ed3f62da628bb3c0 158 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 135 1.1E-12 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MKLM6_RS09165 8bd810264b3c19b0ed3f62da628bb3c0 158 Gene3D G3DSA:3.10.50.40 1 158 6.4E-28 T 28-03-2018 MKLM6_RS19695 29d5918ef422d8ce85aa835e3ef9673c 276 SUPERFAMILY SSF49503 39 149 1.93E-12 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS19695 29d5918ef422d8ce85aa835e3ef9673c 276 Gene3D G3DSA:2.60.40.420 40 162 2.2E-11 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 Pfam PF13426 PAS domain 552 654 1.0E-12 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 SUPERFAMILY SSF55785 274 390 5.41E-14 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 Gene3D G3DSA:3.30.70.270 661 833 4.6E-62 T 28-03-2018 MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 Gene3D G3DSA:3.30.450.20 406 538 8.3E-23 T 28-03-2018 MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 Gene3D G3DSA:3.30.450.20 539 660 2.7E-25 T 28-03-2018 MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 SMART SM00052 837 1084 3.8E-106 T 28-03-2018 IPR001633 EAL domain MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 SMART SM00267 655 827 2.7E-69 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 SMART SM00086 491 533 0.23 T 28-03-2018 IPR001610 PAC motif MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 SMART SM00086 613 655 0.0028 T 28-03-2018 IPR001610 PAC motif MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 SUPERFAMILY SSF55073 671 828 8.63E-52 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 SUPERFAMILY SSF55785 552 660 5.8E-23 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 Pfam PF08448 PAS fold 425 534 1.4E-13 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 Pfam PF00990 Diguanylate cyclase, GGDEF domain 666 823 2.5E-52 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 Gene3D G3DSA:3.20.20.450 834 1088 1.2E-96 T 28-03-2018 IPR001633 EAL domain MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 SUPERFAMILY SSF141868 843 1091 7.85E-87 T 28-03-2018 IPR001633 EAL domain MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 SUPERFAMILY SSF55785 402 531 1.05E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 Gene3D G3DSA:3.30.450.20 265 405 1.0E-18 T 28-03-2018 MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 664 826 6.8E-45 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 549 660 4.7E-19 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 415 539 5.5E-13 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 282 412 9.7E-11 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 Pfam PF17159 Membrane-associated sensor domain 44 269 5.0E-63 T 28-03-2018 IPR033425 Membrane-associated sensor domain MASE3 MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 SMART SM00091 417 484 40.0 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 SMART SM00091 541 607 1.8E-6 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 SMART SM00091 285 354 7.6E-6 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 Pfam PF13188 PAS domain 286 342 8.6E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS11385 437ac9b00671116e787a03ac358d8c36 1100 Pfam PF00563 EAL domain 843 1079 3.8E-69 T 28-03-2018 IPR001633 EAL domain MKLM6_RS01015 0a3fde2ea30ca137cae521b230766ed5 373 Gene3D G3DSA:2.30.130.10 281 372 4.0E-29 T 28-03-2018 IPR002478 PUA domain GO:0003723 MKLM6_RS01015 0a3fde2ea30ca137cae521b230766ed5 373 TIGRFAM TIGR01027 proB: glutamate 5-kinase 10 371 6.1E-127 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MKLM6_RS01015 0a3fde2ea30ca137cae521b230766ed5 373 PIRSF PIRSF000729 6 373 7.8E-127 T 28-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 MKLM6_RS01015 0a3fde2ea30ca137cae521b230766ed5 373 ProSitePatterns PS00902 Glutamate 5-kinase signature. 212 229 - T 28-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MKLM6_RS01015 0a3fde2ea30ca137cae521b230766ed5 373 PRINTS PR00474 Glutamate 5-kinase family signature 47 61 1.6E-47 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MKLM6_RS01015 0a3fde2ea30ca137cae521b230766ed5 373 PRINTS PR00474 Glutamate 5-kinase family signature 121 142 1.6E-47 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MKLM6_RS01015 0a3fde2ea30ca137cae521b230766ed5 373 PRINTS PR00474 Glutamate 5-kinase family signature 153 180 1.6E-47 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MKLM6_RS01015 0a3fde2ea30ca137cae521b230766ed5 373 PRINTS PR00474 Glutamate 5-kinase family signature 81 109 1.6E-47 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MKLM6_RS01015 0a3fde2ea30ca137cae521b230766ed5 373 PRINTS PR00474 Glutamate 5-kinase family signature 214 234 1.6E-47 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MKLM6_RS01015 0a3fde2ea30ca137cae521b230766ed5 373 SUPERFAMILY SSF53633 10 262 1.57E-68 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MKLM6_RS01015 0a3fde2ea30ca137cae521b230766ed5 373 Gene3D G3DSA:3.40.1160.10 1 270 3.9E-62 T 28-03-2018 MKLM6_RS01015 0a3fde2ea30ca137cae521b230766ed5 373 SUPERFAMILY SSF88697 282 372 2.05E-22 T 28-03-2018 IPR015947 PUA-like domain MKLM6_RS01015 0a3fde2ea30ca137cae521b230766ed5 373 Hamap MF_00456 Glutamate 5-kinase [proB]. 10 268 35.571 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MKLM6_RS01015 0a3fde2ea30ca137cae521b230766ed5 373 Pfam PF00696 Amino acid kinase family 10 239 3.5E-44 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MKLM6_RS01015 0a3fde2ea30ca137cae521b230766ed5 373 SMART SM00359 282 365 1.8E-11 T 28-03-2018 IPR002478 PUA domain GO:0003723 MKLM6_RS01015 0a3fde2ea30ca137cae521b230766ed5 373 Pfam PF01472 PUA domain 282 356 2.9E-19 T 28-03-2018 IPR002478 PUA domain GO:0003723 MKLM6_RS00755 5eee3716200f635312dd5e241f44f822 238 Gene3D G3DSA:1.10.10.200 3 76 1.9E-19 T 28-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like MKLM6_RS00755 5eee3716200f635312dd5e241f44f822 238 Pfam PF01709 Transcriptional regulator 4 235 1.0E-68 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS00755 5eee3716200f635312dd5e241f44f822 238 Gene3D G3DSA:3.30.70.980 179 237 4.9E-4 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS00755 5eee3716200f635312dd5e241f44f822 238 Gene3D G3DSA:3.30.70.980 80 175 1.9E-23 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS00755 5eee3716200f635312dd5e241f44f822 238 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 238 26.079 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS00755 5eee3716200f635312dd5e241f44f822 238 SUPERFAMILY SSF75625 1 237 1.57E-71 T 28-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS14890 6a26d09210b3e4cb753453a9400191f6 412 PIRSF PIRSF000151 1 412 2.2E-179 T 28-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 MKLM6_RS14890 6a26d09210b3e4cb753453a9400191f6 412 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 1 411 41.258 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MKLM6_RS14890 6a26d09210b3e4cb753453a9400191f6 412 Gene3D G3DSA:3.40.605.10 237 412 6.7E-45 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MKLM6_RS14890 6a26d09210b3e4cb753453a9400191f6 412 Pfam PF00171 Aldehyde dehydrogenase family 6 277 1.4E-16 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MKLM6_RS14890 6a26d09210b3e4cb753453a9400191f6 412 Pfam PF00171 Aldehyde dehydrogenase family 293 368 2.5E-9 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MKLM6_RS14890 6a26d09210b3e4cb753453a9400191f6 412 SUPERFAMILY SSF53720 2 411 4.06E-121 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MKLM6_RS14890 6a26d09210b3e4cb753453a9400191f6 412 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 318 339 - T 28-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MKLM6_RS14890 6a26d09210b3e4cb753453a9400191f6 412 Gene3D G3DSA:3.40.605.10 1 236 1.5E-43 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MKLM6_RS14890 6a26d09210b3e4cb753453a9400191f6 412 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 8 401 1.2E-151 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MKLM6_RS12810 50d3f95c1d8dce156ae35ec6d0e0854a 173 Pfam PF01475 Ferric uptake regulator family 34 151 1.2E-10 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 MKLM6_RS12810 50d3f95c1d8dce156ae35ec6d0e0854a 173 Gene3D G3DSA:1.10.10.10 11 103 1.4E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS12810 50d3f95c1d8dce156ae35ec6d0e0854a 173 SUPERFAMILY SSF46785 27 157 3.82E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS00645 046a71f2fe0e108027d29c382210670e 457 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 70 3.9E-21 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MKLM6_RS00645 046a71f2fe0e108027d29c382210670e 457 SUPERFAMILY SSF50615 1 71 2.28E-25 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MKLM6_RS00645 046a71f2fe0e108027d29c382210670e 457 Gene3D G3DSA:1.10.1140.10 345 455 3.8E-45 T 28-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MKLM6_RS00645 046a71f2fe0e108027d29c382210670e 457 Gene3D G3DSA:2.40.10.170 1 72 8.3E-29 T 28-03-2018 MKLM6_RS00645 046a71f2fe0e108027d29c382210670e 457 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 127 339 5.7E-64 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MKLM6_RS00645 046a71f2fe0e108027d29c382210670e 457 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 330 339 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MKLM6_RS00645 046a71f2fe0e108027d29c382210670e 457 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 457 56.769 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 MKLM6_RS00645 046a71f2fe0e108027d29c382210670e 457 SUPERFAMILY SSF47917 342 456 7.59E-54 T 28-03-2018 MKLM6_RS00645 046a71f2fe0e108027d29c382210670e 457 Gene3D G3DSA:3.40.50.300 73 344 9.3E-91 T 28-03-2018 MKLM6_RS00645 046a71f2fe0e108027d29c382210670e 457 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 457 3.6E-257 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 MKLM6_RS00645 046a71f2fe0e108027d29c382210670e 457 SUPERFAMILY SSF52540 74 345 6.77E-92 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS09865 f65b24736c04eff27c3ad6e70210c071 328 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 17 291 9.2E-60 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 MKLM6_RS09865 f65b24736c04eff27c3ad6e70210c071 328 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 14 325 15.856 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 MKLM6_RS09865 f65b24736c04eff27c3ad6e70210c071 328 Pfam PF01867 CRISPR associated protein Cas1 22 287 1.2E-12 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 MKLM6_RS09865 f65b24736c04eff27c3ad6e70210c071 328 TIGRFAM TIGR03637 cas1_YPEST: CRISPR-associated endonuclease Cas1, subtype I-F/YPEST 10 309 3.6E-145 T 28-03-2018 IPR019857 CRISPR-associated protein Cas1, YPEST subtype GO:0004520|GO:0043571|GO:0046872 MKLM6_RS15710 4b9f73ce0339dd1017cb6b521dbb47d3 161 TIGRFAM TIGR01935 NOT-MenG: RraA family 5 156 2.0E-58 T 28-03-2018 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 MKLM6_RS15710 4b9f73ce0339dd1017cb6b521dbb47d3 161 Pfam PF03737 Aldolase/RraA 5 155 5.5E-38 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MKLM6_RS15710 4b9f73ce0339dd1017cb6b521dbb47d3 161 Gene3D G3DSA:3.50.30.40 1 161 3.6E-39 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MKLM6_RS15710 4b9f73ce0339dd1017cb6b521dbb47d3 161 SUPERFAMILY SSF89562 1 159 1.57E-41 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MKLM6_RS07470 c81181adc569b63af6d5095b2e34074d 301 Gene3D G3DSA:3.40.190.10 81 174 2.3E-13 T 28-03-2018 MKLM6_RS07470 c81181adc569b63af6d5095b2e34074d 301 SUPERFAMILY SSF53850 89 295 8.87E-37 T 28-03-2018 MKLM6_RS07470 c81181adc569b63af6d5095b2e34074d 301 Gene3D G3DSA:1.10.10.10 2 80 1.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS07470 c81181adc569b63af6d5095b2e34074d 301 Pfam PF03466 LysR substrate binding domain 88 294 3.5E-36 T 28-03-2018 IPR005119 LysR, substrate-binding MKLM6_RS07470 c81181adc569b63af6d5095b2e34074d 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.2E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS07470 c81181adc569b63af6d5095b2e34074d 301 Gene3D G3DSA:3.40.190.10 175 266 3.6E-19 T 28-03-2018 MKLM6_RS07470 c81181adc569b63af6d5095b2e34074d 301 SUPERFAMILY SSF46785 3 86 9.85E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS10830 ca2dadc52f379ac01b157f699972c4fa 319 SUPERFAMILY SSF53474 13 314 1.99E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS10830 ca2dadc52f379ac01b157f699972c4fa 319 Gene3D G3DSA:3.40.50.1820 24 315 1.3E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS10830 ca2dadc52f379ac01b157f699972c4fa 319 Pfam PF05448 Acetyl xylan esterase (AXE1) 26 306 4.7E-28 T 28-03-2018 IPR008391 Acetyl xylan esterase MKLM6_RS13950 85eed3b64eda256f0ba7b68c66e59f5e 436 Pfam PF01979 Amidohydrolase family 60 408 1.1E-70 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MKLM6_RS13950 85eed3b64eda256f0ba7b68c66e59f5e 436 Gene3D G3DSA:2.30.40.10 1 75 1.2E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MKLM6_RS13950 85eed3b64eda256f0ba7b68c66e59f5e 436 Gene3D G3DSA:3.20.20.140 76 360 5.3E-59 T 28-03-2018 MKLM6_RS13950 85eed3b64eda256f0ba7b68c66e59f5e 436 SUPERFAMILY SSF51338 4 62 3.02E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MKLM6_RS13950 85eed3b64eda256f0ba7b68c66e59f5e 436 SUPERFAMILY SSF51338 360 434 3.02E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MKLM6_RS13950 85eed3b64eda256f0ba7b68c66e59f5e 436 SUPERFAMILY SSF51556 62 361 1.15E-95 T 28-03-2018 IPR032466 Metal-dependent hydrolase MKLM6_RS20380 a02a312b7faa562f8441c4639578b57c 229 Pfam PF04340 Protein of unknown function, DUF484 5 218 4.7E-52 T 28-03-2018 IPR007435 Protein of unknown function DUF484 MKLM6_RS20380 a02a312b7faa562f8441c4639578b57c 229 Gene3D G3DSA:3.30.450.40 43 226 4.5E-9 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 SUPERFAMILY SSF55785 413 536 8.23E-22 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 920 1082 3.4E-48 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 Pfam PF13426 PAS domain 683 788 7.5E-8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 Pfam PF13426 PAS domain 808 910 4.8E-12 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 Gene3D G3DSA:3.40.50.10600 798 923 5.3E-24 T 28-03-2018 MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 676 794 2.6E-13 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 421 543 4.0E-17 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 305 408 4.1E-11 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 546 671 1.6E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 807 917 1.2E-14 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 Pfam PF05231 MASE1 18 289 1.2E-20 T 28-03-2018 IPR007895 MASE1 MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 SMART SM00267 911 1083 1.1E-71 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 Gene3D G3DSA:3.30.450.20 414 546 1.7E-26 T 28-03-2018 MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 Pfam PF08448 PAS fold 430 539 3.4E-21 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 Pfam PF08448 PAS fold 308 408 5.1E-12 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 Gene3D G3DSA:3.30.70.270 924 1091 1.4E-62 T 28-03-2018 MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 SUPERFAMILY SSF55785 807 906 5.39E-25 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 Pfam PF00990 Diguanylate cyclase, GGDEF domain 922 1079 3.9E-55 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 SMART SM00086 496 538 320.0 T 28-03-2018 IPR001610 PAC motif MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 SMART SM00086 869 911 0.0018 T 28-03-2018 IPR001610 PAC motif MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 SMART SM00086 749 789 4.3 T 28-03-2018 IPR001610 PAC motif MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 SMART SM00086 625 667 1.0E-5 T 28-03-2018 IPR001610 PAC motif MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 SMART SM00091 550 618 2.1E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 SMART SM00091 424 490 1.1E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 SMART SM00091 797 863 1.9E-8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 SMART SM00091 302 368 1.6E-7 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 SMART SM00091 673 739 2.6 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 SUPERFAMILY SSF55073 927 1084 5.57E-52 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 SUPERFAMILY SSF141868 1099 1346 2.48E-88 T 28-03-2018 IPR001633 EAL domain MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 Pfam PF08447 PAS fold 573 660 1.7E-16 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 SMART SM00052 1093 1340 7.8E-114 T 28-03-2018 IPR001633 EAL domain MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 Gene3D G3DSA:3.30.450.20 547 674 1.5E-26 T 28-03-2018 MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 SUPERFAMILY SSF55785 288 404 1.74E-17 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 Gene3D G3DSA:3.20.20.450 1092 1350 3.9E-98 T 28-03-2018 IPR001633 EAL domain MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 Gene3D G3DSA:3.30.450.20 675 797 2.3E-15 T 28-03-2018 MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 SUPERFAMILY SSF55785 557 669 2.74E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 SUPERFAMILY SSF55785 686 797 1.5E-16 T 28-03-2018 IPR000014 PAS domain MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 Gene3D G3DSA:3.30.450.20 283 413 2.0E-18 T 28-03-2018 MKLM6_RS17230 c8dd7197f6dc56a567fdbd090334d899 1375 Pfam PF00563 EAL domain 1099 1335 3.1E-73 T 28-03-2018 IPR001633 EAL domain MKLM6_RS04690 65c5f62dd27acb974f896cf3a145c36c 160 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 160 28.46 T 28-03-2018 IPR007551 Protein of unknown function DUF520 MKLM6_RS04690 65c5f62dd27acb974f896cf3a145c36c 160 Pfam PF04461 Protein of unknown function (DUF520) 2 159 5.8E-65 T 28-03-2018 IPR007551 Protein of unknown function DUF520 MKLM6_RS04690 65c5f62dd27acb974f896cf3a145c36c 160 Gene3D G3DSA:3.30.70.990 10 94 7.5E-29 T 28-03-2018 IPR035570 UPF0234 N-terminal domain MKLM6_RS04690 65c5f62dd27acb974f896cf3a145c36c 160 SUPERFAMILY SSF89963 88 160 1.44E-30 T 28-03-2018 IPR007551 Protein of unknown function DUF520 MKLM6_RS04690 65c5f62dd27acb974f896cf3a145c36c 160 SUPERFAMILY SSF89963 2 85 5.23E-29 T 28-03-2018 IPR007551 Protein of unknown function DUF520 MKLM6_RS04690 65c5f62dd27acb974f896cf3a145c36c 160 Gene3D G3DSA:3.30.70.860 95 159 2.4E-34 T 28-03-2018 IPR035571 UPF0234/UPF0381 domain MKLM6_RS09155 78e6d89e28a7861bdde3bdbcb70eb832 405 Gene3D G3DSA:1.20.1250.20 6 201 2.3E-19 T 28-03-2018 MKLM6_RS09155 78e6d89e28a7861bdde3bdbcb70eb832 405 Pfam PF05977 Transmembrane secretion effector 26 394 9.6E-28 T 28-03-2018 IPR010290 Transmembrane secretion effector MKLM6_RS09155 78e6d89e28a7861bdde3bdbcb70eb832 405 Gene3D G3DSA:1.20.1250.20 218 405 3.3E-11 T 28-03-2018 MKLM6_RS09155 78e6d89e28a7861bdde3bdbcb70eb832 405 SUPERFAMILY SSF103473 11 403 9.68E-35 T 28-03-2018 IPR020846 Major facilitator superfamily domain MKLM6_RS01455 5888980bd49a27016f6380649505240a 148 Gene3D G3DSA:3.40.630.30 1 146 3.2E-33 T 28-03-2018 MKLM6_RS01455 5888980bd49a27016f6380649505240a 148 Pfam PF00583 Acetyltransferase (GNAT) family 33 135 5.9E-20 T 28-03-2018 IPR000182 GNAT domain GO:0008080 MKLM6_RS01455 5888980bd49a27016f6380649505240a 148 SUPERFAMILY SSF55729 1 142 1.58E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS10120 76e239ec974204eab65b12015ee471bf 782 Pfam PF13426 PAS domain 281 383 0.0061 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10120 76e239ec974204eab65b12015ee471bf 782 SMART SM00091 269 338 70.0 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10120 76e239ec974204eab65b12015ee471bf 782 SMART SM00091 8 75 0.044 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10120 76e239ec974204eab65b12015ee471bf 782 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 24 112 2.6E-13 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10120 76e239ec974204eab65b12015ee471bf 782 SUPERFAMILY SSF58104 449 730 1.48E-69 T 28-03-2018 MKLM6_RS10120 76e239ec974204eab65b12015ee471bf 782 SUPERFAMILY SSF55785 20 114 4.89E-26 T 28-03-2018 IPR000014 PAS domain MKLM6_RS10120 76e239ec974204eab65b12015ee471bf 782 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 580 607 3.6E-50 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MKLM6_RS10120 76e239ec974204eab65b12015ee471bf 782 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 503 532 3.6E-50 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MKLM6_RS10120 76e239ec974204eab65b12015ee471bf 782 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 657 686 3.6E-50 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MKLM6_RS10120 76e239ec974204eab65b12015ee471bf 782 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 609 638 3.6E-50 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MKLM6_RS10120 76e239ec974204eab65b12015ee471bf 782 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 542 697 5.9E-52 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS10120 76e239ec974204eab65b12015ee471bf 782 SMART SM00283 482 729 2.9E-89 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS10120 76e239ec974204eab65b12015ee471bf 782 Gene3D G3DSA:1.10.287.950 251 539 3.0E-19 T 28-03-2018 MKLM6_RS10120 76e239ec974204eab65b12015ee471bf 782 Gene3D G3DSA:1.10.287.950 540 733 1.1E-45 T 28-03-2018 MKLM6_RS10120 76e239ec974204eab65b12015ee471bf 782 Gene3D G3DSA:3.40.50.10600 12 129 1.4E-26 T 28-03-2018 MKLM6_RS10120 76e239ec974204eab65b12015ee471bf 782 Pfam PF08447 PAS fold 31 114 4.4E-17 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS01725 5d1dd4b99e38cc0636aa94c6f3d6bd44 229 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 50 228 3.7E-53 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 MKLM6_RS01725 5d1dd4b99e38cc0636aa94c6f3d6bd44 229 SUPERFAMILY SSF53335 6 228 2.39E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS01725 5d1dd4b99e38cc0636aa94c6f3d6bd44 229 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 16 229 30.042 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 MKLM6_RS01725 5d1dd4b99e38cc0636aa94c6f3d6bd44 229 Pfam PF02390 Putative methyltransferase 54 224 1.0E-52 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 MKLM6_RS01725 5d1dd4b99e38cc0636aa94c6f3d6bd44 229 Gene3D G3DSA:3.40.50.150 22 229 5.1E-22 T 28-03-2018 MKLM6_RS05720 46111363988a334ff451eafcba34accc 184 Pfam PF05706 Cyclin-dependent kinase inhibitor 3 (CDKN3) 45 149 1.2E-9 T 28-03-2018 IPR022778 CDKN3 domain GO:0004721|GO:0004725 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS05720 46111363988a334ff451eafcba34accc 184 Gene3D G3DSA:3.90.190.10 8 184 7.2E-22 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like MKLM6_RS05720 46111363988a334ff451eafcba34accc 184 SMART SM00404 87 183 0.0018 T 28-03-2018 IPR003595 Protein-tyrosine phosphatase, catalytic MKLM6_RS05720 46111363988a334ff451eafcba34accc 184 SUPERFAMILY SSF52799 38 180 2.99E-35 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like MKLM6_RS18635 cfe967a19a287a2fca7dce88cd467de0 389 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 42.006 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MKLM6_RS18635 cfe967a19a287a2fca7dce88cd467de0 389 Pfam PF00549 CoA-ligase 262 381 1.2E-22 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MKLM6_RS18635 cfe967a19a287a2fca7dce88cd467de0 389 SUPERFAMILY SSF56059 1 238 1.73E-74 T 28-03-2018 MKLM6_RS18635 cfe967a19a287a2fca7dce88cd467de0 389 Pfam PF08442 ATP-grasp domain 2 202 4.9E-74 T 28-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MKLM6_RS18635 cfe967a19a287a2fca7dce88cd467de0 389 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 28-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MKLM6_RS18635 cfe967a19a287a2fca7dce88cd467de0 389 Gene3D G3DSA:3.30.1490.20 21 95 3.0E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MKLM6_RS18635 cfe967a19a287a2fca7dce88cd467de0 389 SUPERFAMILY SSF52210 241 385 1.11E-49 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MKLM6_RS18635 cfe967a19a287a2fca7dce88cd467de0 389 Gene3D G3DSA:3.40.50.261 240 385 2.6E-41 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MKLM6_RS18635 cfe967a19a287a2fca7dce88cd467de0 389 PIRSF PIRSF001554 1 388 1.0E-145 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MKLM6_RS18635 cfe967a19a287a2fca7dce88cd467de0 389 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 7.8E-155 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MKLM6_RS18635 cfe967a19a287a2fca7dce88cd467de0 389 Gene3D G3DSA:3.30.470.20 96 239 5.6E-53 T 28-03-2018 MKLM6_RS13795 db81c1a2c2cebf999c2db77657e55a55 431 Pfam PF00709 Adenylosuccinate synthetase 5 423 4.8E-178 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MKLM6_RS13795 db81c1a2c2cebf999c2db77657e55a55 431 SMART SM00788 4 424 1.0E-291 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MKLM6_RS13795 db81c1a2c2cebf999c2db77657e55a55 431 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 431 208.843 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MKLM6_RS13795 db81c1a2c2cebf999c2db77657e55a55 431 Gene3D G3DSA:3.40.440.10 1 155 4.2E-53 T 28-03-2018 MKLM6_RS13795 db81c1a2c2cebf999c2db77657e55a55 431 Gene3D G3DSA:3.40.440.10 156 266 1.9E-25 T 28-03-2018 MKLM6_RS13795 db81c1a2c2cebf999c2db77657e55a55 431 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 429 1.6E-184 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MKLM6_RS13795 db81c1a2c2cebf999c2db77657e55a55 431 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 133 144 - T 28-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MKLM6_RS13795 db81c1a2c2cebf999c2db77657e55a55 431 SUPERFAMILY SSF52540 3 429 4.36E-176 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS13795 db81c1a2c2cebf999c2db77657e55a55 431 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 11 18 - T 28-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MKLM6_RS13795 db81c1a2c2cebf999c2db77657e55a55 431 Gene3D G3DSA:3.90.170.10 267 431 1.2E-65 T 28-03-2018 MKLM6_RS13595 d5ed629e17eebe8d36124c8cd69eb30b 328 Gene3D G3DSA:3.30.1180.20 180 328 2.6E-48 T 28-03-2018 MKLM6_RS13595 d5ed629e17eebe8d36124c8cd69eb30b 328 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 324 1.1E-130 T 28-03-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 MKLM6_RS13595 d5ed629e17eebe8d36124c8cd69eb30b 328 Gene3D G3DSA:3.40.50.10440 11 179 9.7E-62 T 28-03-2018 MKLM6_RS13595 d5ed629e17eebe8d36124c8cd69eb30b 328 Pfam PF02733 Dak1 domain 17 322 3.4E-119 T 28-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MKLM6_RS13595 d5ed629e17eebe8d36124c8cd69eb30b 328 SUPERFAMILY SSF82549 1 326 5.23E-113 T 28-03-2018 MKLM6_RS03875 218a2830f2b28731ca50479d3db67944 345 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 345 180.276 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 MKLM6_RS03875 218a2830f2b28731ca50479d3db67944 345 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 7 238 2.3E-117 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 MKLM6_RS03875 218a2830f2b28731ca50479d3db67944 345 Gene3D G3DSA:1.10.10.10 260 330 3.5E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS03875 218a2830f2b28731ca50479d3db67944 345 Gene3D G3DSA:3.40.50.300 21 184 1.5E-28 T 28-03-2018 MKLM6_RS03875 218a2830f2b28731ca50479d3db67944 345 SUPERFAMILY SSF52540 23 255 1.37E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS03875 218a2830f2b28731ca50479d3db67944 345 SUPERFAMILY SSF46785 260 333 1.36E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS03875 218a2830f2b28731ca50479d3db67944 345 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 256 329 1.1E-33 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 MKLM6_RS03875 218a2830f2b28731ca50479d3db67944 345 SMART SM00382 54 181 5.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS03875 218a2830f2b28731ca50479d3db67944 345 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 253 330 7.0E-30 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 MKLM6_RS03875 218a2830f2b28731ca50479d3db67944 345 Gene3D G3DSA:1.10.8.60 187 257 8.6E-33 T 28-03-2018 MKLM6_RS03875 218a2830f2b28731ca50479d3db67944 345 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 26 329 9.7E-148 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 MKLM6_RS08190 f8e7dcc06837962c43ca7447c331e2b5 319 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 51 299 4.3E-42 T 28-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region MKLM6_RS08190 f8e7dcc06837962c43ca7447c331e2b5 319 Gene3D G3DSA:2.120.10.30 40 310 2.6E-31 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MKLM6_RS08190 f8e7dcc06837962c43ca7447c331e2b5 319 SUPERFAMILY SSF63829 25 313 2.45E-52 T 28-03-2018 MKLM6_RS07385 57482a3b3b513a5792733248b9ce7648 406 Pfam PF00696 Amino acid kinase family 4 229 1.0E-50 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MKLM6_RS07385 57482a3b3b513a5792733248b9ce7648 406 Gene3D G3DSA:3.30.70.260 328 402 4.3E-22 T 28-03-2018 MKLM6_RS07385 57482a3b3b513a5792733248b9ce7648 406 SUPERFAMILY SSF55021 332 404 1.3E-23 T 28-03-2018 MKLM6_RS07385 57482a3b3b513a5792733248b9ce7648 406 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 1 402 7.8E-134 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MKLM6_RS07385 57482a3b3b513a5792733248b9ce7648 406 Gene3D G3DSA:3.40.1160.10 1 234 2.0E-72 T 28-03-2018 MKLM6_RS07385 57482a3b3b513a5792733248b9ce7648 406 SUPERFAMILY SSF53633 4 241 1.07E-73 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MKLM6_RS07385 57482a3b3b513a5792733248b9ce7648 406 Pfam PF13840 ACT domain 338 398 1.2E-16 T 28-03-2018 IPR027795 GATS-like ACT domain MKLM6_RS07385 57482a3b3b513a5792733248b9ce7648 406 PIRSF PIRSF000726 1 62 5.2E-21 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MKLM6_RS07385 57482a3b3b513a5792733248b9ce7648 406 PIRSF PIRSF000726 59 406 1.7E-142 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MKLM6_RS07385 57482a3b3b513a5792733248b9ce7648 406 Gene3D G3DSA:3.30.70.260 235 327 1.1E-22 T 28-03-2018 MKLM6_RS07385 57482a3b3b513a5792733248b9ce7648 406 SUPERFAMILY SSF55021 247 324 1.66E-18 T 28-03-2018 MKLM6_RS07385 57482a3b3b513a5792733248b9ce7648 406 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MKLM6_RS07385 57482a3b3b513a5792733248b9ce7648 406 Pfam PF01842 ACT domain 267 323 8.5E-9 T 28-03-2018 IPR002912 ACT domain MKLM6_RS07385 57482a3b3b513a5792733248b9ce7648 406 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 2 402 5.0E-131 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MKLM6_RS14015 5b227236993717c223b7b68ab1ad8cfe 287 Gene3D G3DSA:3.90.730.10 41 242 3.2E-22 T 28-03-2018 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 Reactome: R-HSA-6798695 MKLM6_RS14015 5b227236993717c223b7b68ab1ad8cfe 287 Pfam PF00445 Ribonuclease T2 family 47 165 1.1E-11 T 28-03-2018 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 Reactome: R-HSA-6798695 MKLM6_RS14015 5b227236993717c223b7b68ab1ad8cfe 287 SUPERFAMILY SSF55895 46 222 1.44E-23 T 28-03-2018 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 Reactome: R-HSA-6798695 MKLM6_RS14015 5b227236993717c223b7b68ab1ad8cfe 287 ProSitePatterns PS00530 Ribonuclease T2 family histidine active site 1. 84 91 - T 28-03-2018 IPR018188 Ribonuclease T2, His active site 1 GO:0003723|GO:0033897 Reactome: R-HSA-6798695 MKLM6_RS16645 1363d7636364c74ad570d0c92dbf317c 231 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS16645 1363d7636364c74ad570d0c92dbf317c 231 SUPERFAMILY SSF52540 4 226 2.05E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS16645 1363d7636364c74ad570d0c92dbf317c 231 SMART SM00382 33 221 3.0E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS16645 1363d7636364c74ad570d0c92dbf317c 231 Pfam PF00005 ABC transporter 24 173 1.9E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS16645 1363d7636364c74ad570d0c92dbf317c 231 Gene3D G3DSA:3.40.50.300 1 229 1.4E-64 T 28-03-2018 MKLM6_RS11795 face38835e2a6a70cd505424d884bf01 213 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 4 197 19.242 T 28-03-2018 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 MKLM6_RS11795 face38835e2a6a70cd505424d884bf01 213 Pfam PF01794 Ferric reductase like transmembrane component 47 157 4.8E-13 T 28-03-2018 IPR013130 Ferric reductase transmembrane component-like domain MKLM6_RS19120 bddef326e4f5f43eff03022420b9691b 450 Pfam PF02954 Bacterial regulatory protein, Fis family 412 448 1.2E-8 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS19120 bddef326e4f5f43eff03022420b9691b 450 Gene3D G3DSA:3.40.50.300 140 316 3.7E-28 T 28-03-2018 MKLM6_RS19120 bddef326e4f5f43eff03022420b9691b 450 SUPERFAMILY SSF55785 32 121 6.28E-9 T 28-03-2018 IPR000014 PAS domain MKLM6_RS19120 bddef326e4f5f43eff03022420b9691b 450 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 168 181 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MKLM6_RS19120 bddef326e4f5f43eff03022420b9691b 450 Pfam PF13426 PAS domain 32 122 4.6E-8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS19120 bddef326e4f5f43eff03022420b9691b 450 SUPERFAMILY SSF52540 144 386 1.3E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS19120 bddef326e4f5f43eff03022420b9691b 450 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 230 245 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MKLM6_RS19120 bddef326e4f5f43eff03022420b9691b 450 SMART SM00382 164 307 2.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS19120 bddef326e4f5f43eff03022420b9691b 450 Pfam PF00158 Sigma-54 interaction domain 145 310 7.8E-69 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MKLM6_RS19120 bddef326e4f5f43eff03022420b9691b 450 Gene3D G3DSA:1.10.8.60 317 387 2.4E-23 T 28-03-2018 MKLM6_RS19120 bddef326e4f5f43eff03022420b9691b 450 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 357 366 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site MKLM6_RS19120 bddef326e4f5f43eff03022420b9691b 450 SUPERFAMILY SSF46689 357 450 6.09E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS19120 bddef326e4f5f43eff03022420b9691b 450 Gene3D G3DSA:3.30.450.20 30 125 2.3E-9 T 28-03-2018 MKLM6_RS19120 bddef326e4f5f43eff03022420b9691b 450 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 431 450 2.8E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS19120 bddef326e4f5f43eff03022420b9691b 450 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 414 431 2.8E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS19120 bddef326e4f5f43eff03022420b9691b 450 Gene3D G3DSA:1.10.10.60 388 450 1.2E-12 T 28-03-2018 MKLM6_RS12305 f1286b2a78077a81800c6d22db74bf37 135 Pfam PF11042 Protein of unknown function (DUF2750) 23 118 4.9E-16 T 28-03-2018 IPR021284 Protein of unknown function DUF2750 MKLM6_RS01045 88f45b0acdfaae70b4348cdc8e1eea46 182 Gene3D G3DSA:2.160.10.10 16 181 2.0E-30 T 28-03-2018 MKLM6_RS01045 88f45b0acdfaae70b4348cdc8e1eea46 182 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 126 158 6.2E-6 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS01045 88f45b0acdfaae70b4348cdc8e1eea46 182 SUPERFAMILY SSF51161 22 180 1.66E-39 T 28-03-2018 IPR011004 Trimeric LpxA-like MKLM6_RS19595 ddac296f4adc1bc9f7dab1e24b9640cd 343 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 3 336 2.1E-111 T 28-03-2018 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 MKLM6_RS19595 ddac296f4adc1bc9f7dab1e24b9640cd 343 Gene3D G3DSA:3.75.10.10 1 342 2.8E-118 T 28-03-2018 MKLM6_RS19595 ddac296f4adc1bc9f7dab1e24b9640cd 343 SUPERFAMILY SSF55909 3 337 2.32E-109 T 28-03-2018 MKLM6_RS02680 ab003b188d3ca18ed9e885a6b54fce96 177 SUPERFAMILY SSF53697 6 176 2.09E-36 T 28-03-2018 MKLM6_RS02680 ab003b188d3ca18ed9e885a6b54fce96 177 Gene3D G3DSA:3.40.50.10490 2 177 3.2E-32 T 28-03-2018 MKLM6_RS02680 ab003b188d3ca18ed9e885a6b54fce96 177 Pfam PF01380 SIS domain 28 136 1.2E-19 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MKLM6_RS02680 ab003b188d3ca18ed9e885a6b54fce96 177 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 4 177 5.7E-65 T 28-03-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 MKLM6_RS21120 b59647ac5a1801e4231e035f2d38f916 207 SUPERFAMILY SSF53639 11 202 1.75E-46 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal MKLM6_RS21120 b59647ac5a1801e4231e035f2d38f916 207 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 15 202 7.2E-69 T 28-03-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 MKLM6_RS21120 b59647ac5a1801e4231e035f2d38f916 207 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 207 102.205 T 28-03-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 MKLM6_RS21120 b59647ac5a1801e4231e035f2d38f916 207 SMART SM01007 13 199 1.3E-55 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal MKLM6_RS21120 b59647ac5a1801e4231e035f2d38f916 207 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 13 198 1.3E-40 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal MKLM6_RS21120 b59647ac5a1801e4231e035f2d38f916 207 Gene3D G3DSA:3.40.225.10 2 206 3.1E-48 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal MKLM6_RS03865 856aaae5787b73b010b975e5f26d4030 165 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 107 126 2.4E-38 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MKLM6_RS03865 856aaae5787b73b010b975e5f26d4030 165 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 61 77 2.4E-38 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MKLM6_RS03865 856aaae5787b73b010b975e5f26d4030 165 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 83 99 2.4E-38 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MKLM6_RS03865 856aaae5787b73b010b975e5f26d4030 165 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 138 150 2.4E-38 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MKLM6_RS03865 856aaae5787b73b010b975e5f26d4030 165 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 5 18 2.4E-38 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MKLM6_RS03865 856aaae5787b73b010b975e5f26d4030 165 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 4 150 2.3E-61 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MKLM6_RS03865 856aaae5787b73b010b975e5f26d4030 165 SUPERFAMILY SSF53098 3 154 7.08E-55 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS03865 856aaae5787b73b010b975e5f26d4030 165 Gene3D G3DSA:3.30.420.10 2 159 1.9E-46 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS03865 856aaae5787b73b010b975e5f26d4030 165 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 4 155 3.0E-65 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MKLM6_RS03865 856aaae5787b73b010b975e5f26d4030 165 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 2 153 45.524 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MKLM6_RS21470 66e101c5360df71a893553a781670f01 92 Pfam PF11839 Alanine-zipper, major outer membrane lipoprotein 24 92 6.6E-17 T 28-03-2018 IPR021793 Major outer membrane lipoprotein Oprl MKLM6_RS21470 66e101c5360df71a893553a781670f01 92 Gene3D G3DSA:1.20.5.320 11 87 4.6E-5 T 28-03-2018 MKLM6_RS02305 e72b4c9aadfb8303bb2feab9ebe83052 523 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 250 276 3.7E-34 T 28-03-2018 MKLM6_RS02305 e72b4c9aadfb8303bb2feab9ebe83052 523 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 88 113 3.7E-34 T 28-03-2018 MKLM6_RS02305 e72b4c9aadfb8303bb2feab9ebe83052 523 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 163 184 3.7E-34 T 28-03-2018 MKLM6_RS02305 e72b4c9aadfb8303bb2feab9ebe83052 523 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 228 249 3.7E-34 T 28-03-2018 MKLM6_RS02305 e72b4c9aadfb8303bb2feab9ebe83052 523 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 318 330 3.7E-34 T 28-03-2018 MKLM6_RS02305 e72b4c9aadfb8303bb2feab9ebe83052 523 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 116 136 3.7E-34 T 28-03-2018 MKLM6_RS02305 e72b4c9aadfb8303bb2feab9ebe83052 523 Pfam PF00361 Proton-conducting membrane transporter 139 360 8.5E-43 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS02305 e72b4c9aadfb8303bb2feab9ebe83052 523 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 72 127 2.2E-7 T 28-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS14585 b3825c1694019cfd60e0c4a9f85b73b8 451 Gene3D G3DSA:1.10.40.30 387 441 9.6E-32 T 28-03-2018 MKLM6_RS14585 b3825c1694019cfd60e0c4a9f85b73b8 451 SUPERFAMILY SSF48557 7 449 8.95E-105 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 MKLM6_RS14585 b3825c1694019cfd60e0c4a9f85b73b8 451 Pfam PF08328 Adenylosuccinate lyase C-terminal 327 441 1.6E-51 T 28-03-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 MKLM6_RS14585 b3825c1694019cfd60e0c4a9f85b73b8 451 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 9 450 1.1E-132 T 28-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MKLM6_RS14585 b3825c1694019cfd60e0c4a9f85b73b8 451 Gene3D G3DSA:1.20.200.10 115 386 2.2E-85 T 28-03-2018 MKLM6_RS14585 b3825c1694019cfd60e0c4a9f85b73b8 451 PRINTS PR00149 Fumarate lyase superfamily signature 290 306 3.4E-17 T 28-03-2018 IPR000362 Fumarate lyase family MKLM6_RS14585 b3825c1694019cfd60e0c4a9f85b73b8 451 PRINTS PR00149 Fumarate lyase superfamily signature 114 132 3.4E-17 T 28-03-2018 IPR000362 Fumarate lyase family MKLM6_RS14585 b3825c1694019cfd60e0c4a9f85b73b8 451 PRINTS PR00149 Fumarate lyase superfamily signature 247 274 3.4E-17 T 28-03-2018 IPR000362 Fumarate lyase family MKLM6_RS14585 b3825c1694019cfd60e0c4a9f85b73b8 451 PRINTS PR00149 Fumarate lyase superfamily signature 159 177 3.4E-17 T 28-03-2018 IPR000362 Fumarate lyase family MKLM6_RS14585 b3825c1694019cfd60e0c4a9f85b73b8 451 Gene3D G3DSA:1.10.275.10 1 114 6.4E-43 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal MKLM6_RS14585 b3825c1694019cfd60e0c4a9f85b73b8 451 ProSitePatterns PS00163 Fumarate lyases signature. 290 299 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MKLM6_RS14585 b3825c1694019cfd60e0c4a9f85b73b8 451 Pfam PF00206 Lyase 11 308 9.5E-66 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal MKLM6_RS02925 a3039e44ffc9b597629d357e2f0a85a3 366 SUPERFAMILY SSF51905 5 217 3.24E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS02925 a3039e44ffc9b597629d357e2f0a85a3 366 SUPERFAMILY SSF51905 308 365 3.24E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS02925 a3039e44ffc9b597629d357e2f0a85a3 366 Gene3D G3DSA:3.50.50.60 1 366 5.8E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS02925 a3039e44ffc9b597629d357e2f0a85a3 366 SUPERFAMILY SSF54373 221 308 4.05E-19 T 28-03-2018 MKLM6_RS02925 a3039e44ffc9b597629d357e2f0a85a3 366 Pfam PF01266 FAD dependent oxidoreductase 6 347 3.3E-62 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MKLM6_RS16820 b02812a083a909fa26ab53d2ba637a8f 430 TIGRFAM TIGR00115 tig: trigger factor 12 412 1.6E-131 T 28-03-2018 IPR005215 Trigger factor GO:0015031 MKLM6_RS16820 b02812a083a909fa26ab53d2ba637a8f 430 SUPERFAMILY SSF54534 130 245 1.14E-30 T 28-03-2018 MKLM6_RS16820 b02812a083a909fa26ab53d2ba637a8f 430 Gene3D G3DSA:1.10.3120.10 209 389 3.1E-44 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 MKLM6_RS16820 b02812a083a909fa26ab53d2ba637a8f 430 Hamap MF_00303 Trigger factor [tig]. 1 418 19.974 T 28-03-2018 IPR005215 Trigger factor GO:0015031 MKLM6_RS16820 b02812a083a909fa26ab53d2ba637a8f 430 Gene3D G3DSA:3.30.70.1050 1 116 3.8E-34 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 MKLM6_RS16820 b02812a083a909fa26ab53d2ba637a8f 430 PIRSF PIRSF003095 1 430 1.0E-117 T 28-03-2018 IPR005215 Trigger factor GO:0015031 MKLM6_RS16820 b02812a083a909fa26ab53d2ba637a8f 430 SUPERFAMILY SSF102735 1 126 2.22E-35 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 MKLM6_RS16820 b02812a083a909fa26ab53d2ba637a8f 430 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 263 412 4.9E-34 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 MKLM6_RS16820 b02812a083a909fa26ab53d2ba637a8f 430 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 154 236 9.3E-15 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MKLM6_RS16820 b02812a083a909fa26ab53d2ba637a8f 430 SUPERFAMILY SSF109998 246 429 1.83E-44 T 28-03-2018 IPR027304 Trigger factor/SurA domain MKLM6_RS16820 b02812a083a909fa26ab53d2ba637a8f 430 Pfam PF05697 Bacterial trigger factor protein (TF) 1 142 1.3E-40 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 MKLM6_RS16670 1e6be384bff9a64d21222af53cf72aed 530 Pfam PF00171 Aldehyde dehydrogenase family 4 449 3.1E-126 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MKLM6_RS16670 1e6be384bff9a64d21222af53cf72aed 530 SUPERFAMILY SSF53720 4 450 5.5E-133 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MKLM6_RS16670 1e6be384bff9a64d21222af53cf72aed 530 Gene3D G3DSA:3.40.605.10 2 252 3.5E-72 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MKLM6_RS16670 1e6be384bff9a64d21222af53cf72aed 530 PIRSF PIRSF036492 17 487 1.6E-89 T 28-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 MKLM6_RS16670 1e6be384bff9a64d21222af53cf72aed 530 Gene3D G3DSA:3.40.309.10 253 439 2.6E-60 T 28-03-2018 MKLM6_RS16670 1e6be384bff9a64d21222af53cf72aed 530 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 233 240 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 MKLM6_RS14210 b76ea706cc5e3a99d375d48da4bb68ee 459 Gene3D G3DSA:2.30.170.30 1 53 5.3E-20 T 28-03-2018 MKLM6_RS14210 b76ea706cc5e3a99d375d48da4bb68ee 459 PIRSF PIRSF018788 1 456 2.6E-229 T 28-03-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 MKLM6_RS14210 b76ea706cc5e3a99d375d48da4bb68ee 459 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 13 442 2.1E-217 T 28-03-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 MKLM6_RS14210 b76ea706cc5e3a99d375d48da4bb68ee 459 Gene3D G3DSA:1.10.220.70 56 137 9.5E-35 T 28-03-2018 MKLM6_RS14210 b76ea706cc5e3a99d375d48da4bb68ee 459 Gene3D G3DSA:3.20.20.70 140 447 2.2E-164 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS02770 f534a2dd91378a0d8fd732ff3c2ac00f 241 PIRSF PIRSF002884 15 241 6.1E-67 T 28-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 MKLM6_RS02770 f534a2dd91378a0d8fd732ff3c2ac00f 241 Gene3D G3DSA:1.10.287.500 58 191 1.4E-18 T 28-03-2018 MKLM6_RS02770 f534a2dd91378a0d8fd732ff3c2ac00f 241 Pfam PF04344 Chemotaxis phosphatase, CheZ 38 241 2.3E-69 T 28-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 MKLM6_RS02770 f534a2dd91378a0d8fd732ff3c2ac00f 241 SUPERFAMILY SSF75708 29 240 1.44E-55 T 28-03-2018 MKLM6_RS04100 2c1897461f4178b4b7b5c374c9f18156 243 TIGRFAM TIGR03370 VPLPA-CTERM: VPLPA-CTERM protein sorting domain 218 241 2.3E-6 T 28-03-2018 IPR022472 VPLPA-CTERM protein sorting domain MKLM6_RS16035 cea48cb7b19754f52f008bd60efc0105 141 SUPERFAMILY SSF55874 26 130 1.14E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS16035 cea48cb7b19754f52f008bd60efc0105 141 Pfam PF13581 Histidine kinase-like ATPase domain 40 138 2.4E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS16035 cea48cb7b19754f52f008bd60efc0105 141 Gene3D G3DSA:3.30.565.10 18 131 5.7E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS16930 baf282726e4c3096620ad4ebac8e1967 308 Pfam PF01063 Amino-transferase class IV 37 267 9.3E-53 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 MKLM6_RS16930 baf282726e4c3096620ad4ebac8e1967 308 Gene3D G3DSA:3.20.10.10 144 296 5.5E-52 T 28-03-2018 MKLM6_RS16930 baf282726e4c3096620ad4ebac8e1967 308 ProSitePatterns PS00770 Aminotransferases class-IV signature. 195 223 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 MKLM6_RS16930 baf282726e4c3096620ad4ebac8e1967 308 Gene3D G3DSA:3.30.470.10 1 143 4.9E-41 T 28-03-2018 MKLM6_RS16930 baf282726e4c3096620ad4ebac8e1967 308 SUPERFAMILY SSF56752 3 304 2.22E-103 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 MKLM6_RS16930 baf282726e4c3096620ad4ebac8e1967 308 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 12 307 3.7E-135 T 28-03-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 MKLM6_RS09980 c0f2cfeac840868e86be99b01aef68ae 766 Pfam PF00801 PKD domain 576 640 1.7E-15 T 28-03-2018 IPR000601 PKD domain MKLM6_RS09980 c0f2cfeac840868e86be99b01aef68ae 766 Gene3D G3DSA:2.60.120.380 411 556 1.8E-9 T 28-03-2018 MKLM6_RS09980 c0f2cfeac840868e86be99b01aef68ae 766 Gene3D G3DSA:3.40.390.10 255 410 1.2E-6 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 MKLM6_RS09980 c0f2cfeac840868e86be99b01aef68ae 766 SUPERFAMILY SSF55486 264 406 6.83E-8 T 28-03-2018 MKLM6_RS09980 c0f2cfeac840868e86be99b01aef68ae 766 SUPERFAMILY SSF49299 564 646 8.11E-21 T 28-03-2018 IPR000601 PKD domain MKLM6_RS09980 c0f2cfeac840868e86be99b01aef68ae 766 SMART SM00089 567 651 9.5E-25 T 28-03-2018 IPR022409 PKD/Chitinase domain MKLM6_RS09980 c0f2cfeac840868e86be99b01aef68ae 766 Gene3D G3DSA:2.60.40.10 560 653 1.1E-21 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS10605 49890bc09d11159960eb9aad97da6178 396 Gene3D G3DSA:3.30.70.270 215 395 2.1E-55 T 28-03-2018 MKLM6_RS10605 49890bc09d11159960eb9aad97da6178 396 Gene3D G3DSA:3.30.450.40 24 214 1.1E-23 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS10605 49890bc09d11159960eb9aad97da6178 396 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 219 388 3.0E-49 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS10605 49890bc09d11159960eb9aad97da6178 396 Pfam PF00990 Diguanylate cyclase, GGDEF domain 222 384 3.3E-45 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS10605 49890bc09d11159960eb9aad97da6178 396 SUPERFAMILY SSF55781 26 191 9.16E-23 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS10605 49890bc09d11159960eb9aad97da6178 396 SMART SM00065 42 193 1.1E-15 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS10605 49890bc09d11159960eb9aad97da6178 396 SUPERFAMILY SSF55073 226 390 5.49E-48 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS10605 49890bc09d11159960eb9aad97da6178 396 Pfam PF13185 GAF domain 42 174 1.9E-12 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS10605 49890bc09d11159960eb9aad97da6178 396 SMART SM00267 210 388 1.2E-61 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS21345 39faa0f0bee8e03489ba6510010feb8f 122 Hamap MF_00048 UPF0102 protein YraN [yraN]. 10 120 20.524 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 MKLM6_RS21345 39faa0f0bee8e03489ba6510010feb8f 122 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 11 121 4.8E-28 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 MKLM6_RS21345 39faa0f0bee8e03489ba6510010feb8f 122 Gene3D G3DSA:3.40.1350.10 16 122 9.7E-36 T 28-03-2018 MKLM6_RS21345 39faa0f0bee8e03489ba6510010feb8f 122 SUPERFAMILY SSF52980 11 121 2.79E-19 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MKLM6_RS21345 39faa0f0bee8e03489ba6510010feb8f 122 Pfam PF02021 Uncharacterised protein family UPF0102 17 107 2.6E-27 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 MKLM6_RS11325 6b59011d0dfa283a1e1ee0998531eac6 248 Pfam PF02308 MgtC family 29 158 1.8E-32 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MKLM6_RS11325 6b59011d0dfa283a1e1ee0998531eac6 248 PRINTS PR01837 MgtC/SapB protein signature 50 68 1.3E-38 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MKLM6_RS11325 6b59011d0dfa283a1e1ee0998531eac6 248 PRINTS PR01837 MgtC/SapB protein signature 113 137 1.3E-38 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MKLM6_RS11325 6b59011d0dfa283a1e1ee0998531eac6 248 PRINTS PR01837 MgtC/SapB protein signature 31 50 1.3E-38 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MKLM6_RS11325 6b59011d0dfa283a1e1ee0998531eac6 248 PRINTS PR01837 MgtC/SapB protein signature 86 108 1.3E-38 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MKLM6_RS05895 d76fbe165759a6e630c4f469514ce327 1259 Gene3D G3DSA:3.20.20.80 919 1162 4.7E-9 T 28-03-2018 MKLM6_RS05895 d76fbe165759a6e630c4f469514ce327 1259 Gene3D G3DSA:2.60.120.260 263 408 4.5E-4 T 28-03-2018 IPR008979 Galactose-binding domain-like MKLM6_RS05895 d76fbe165759a6e630c4f469514ce327 1259 SUPERFAMILY SSF51445 912 1122 2.17E-11 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily MKLM6_RS05895 d76fbe165759a6e630c4f469514ce327 1259 Gene3D G3DSA:2.60.120.260 594 687 0.014 T 28-03-2018 IPR008979 Galactose-binding domain-like MKLM6_RS05895 d76fbe165759a6e630c4f469514ce327 1259 Gene3D G3DSA:2.60.120.260 688 760 0.14 T 28-03-2018 IPR008979 Galactose-binding domain-like MKLM6_RS02355 198b1f3ccefb172a54eb6a3c433b9c24 491 Gene3D G3DSA:3.40.50.150 144 449 2.8E-54 T 28-03-2018 MKLM6_RS02355 198b1f3ccefb172a54eb6a3c433b9c24 491 SUPERFAMILY SSF53335 5 490 1.22E-127 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS02355 198b1f3ccefb172a54eb6a3c433b9c24 491 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 294 318 2.8E-21 T 28-03-2018 MKLM6_RS02355 198b1f3ccefb172a54eb6a3c433b9c24 491 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 146 162 2.8E-21 T 28-03-2018 MKLM6_RS02355 198b1f3ccefb172a54eb6a3c433b9c24 491 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 170 184 2.8E-21 T 28-03-2018 MKLM6_RS02355 198b1f3ccefb172a54eb6a3c433b9c24 491 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 252 264 2.8E-21 T 28-03-2018 MKLM6_RS02355 198b1f3ccefb172a54eb6a3c433b9c24 491 Pfam PF12161 HsdM N-terminal domain 6 112 6.0E-13 T 28-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain MKLM6_RS02355 198b1f3ccefb172a54eb6a3c433b9c24 491 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 255 261 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MKLM6_RS02355 198b1f3ccefb172a54eb6a3c433b9c24 491 Pfam PF02384 N-6 DNA Methylase 124 411 4.2E-73 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 MKLM6_RS01060 166a43e75db06e99f6035f5a61100ec1 304 SUPERFAMILY SSF53448 3 142 9.64E-22 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS01060 166a43e75db06e99f6035f5a61100ec1 304 Gene3D G3DSA:3.90.550.10 3 270 3.1E-21 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS01060 166a43e75db06e99f6035f5a61100ec1 304 Pfam PF00535 Glycosyl transferase family 2 5 92 4.2E-13 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MKLM6_RS15950 06be8e63dbaf615672d8a620c4be5681 562 Pfam PF02463 RecF/RecN/SMC N terminal domain 16 512 1.2E-18 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal MKLM6_RS15950 06be8e63dbaf615672d8a620c4be5681 562 Gene3D G3DSA:3.40.50.300 1 235 1.8E-24 T 28-03-2018 MKLM6_RS15950 06be8e63dbaf615672d8a620c4be5681 562 Gene3D G3DSA:3.40.50.300 248 535 3.0E-22 T 28-03-2018 MKLM6_RS15950 06be8e63dbaf615672d8a620c4be5681 562 SUPERFAMILY SSF52540 1 217 3.85E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS15950 06be8e63dbaf615672d8a620c4be5681 562 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 553 2.2E-168 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 MKLM6_RS15950 06be8e63dbaf615672d8a620c4be5681 562 PIRSF PIRSF003128 1 557 1.1E-162 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 MKLM6_RS15950 06be8e63dbaf615672d8a620c4be5681 562 SUPERFAMILY SSF52540 4 50 3.05E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS15950 06be8e63dbaf615672d8a620c4be5681 562 SUPERFAMILY SSF52540 284 510 3.05E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS17080 0b4edec5eeca593f88072ba819028c3a 316 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 13 36 6.3E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS17080 0b4edec5eeca593f88072ba819028c3a 316 Gene3D G3DSA:3.30.700.10 16 294 2.9E-7 T 28-03-2018 MKLM6_RS17080 0b4edec5eeca593f88072ba819028c3a 316 SUPERFAMILY SSF54523 16 93 1.1E-11 T 28-03-2018 MKLM6_RS17080 0b4edec5eeca593f88072ba819028c3a 316 Pfam PF07963 Prokaryotic N-terminal methylation motif 11 36 6.2E-7 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS17080 0b4edec5eeca593f88072ba819028c3a 316 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 14 34 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS02580 6a1fd3d9243427833fdd5d21b22ad09a 385 Pfam PF04375 HemX, putative uroporphyrinogen-III C-methyltransferase 23 361 4.4E-55 T 28-03-2018 IPR007470 Putative uroporphyrinogen-III C-methyltransferase HemX MKLM6_RS02580 6a1fd3d9243427833fdd5d21b22ad09a 385 Gene3D G3DSA:3.90.20.10 21 201 9.3E-5 T 28-03-2018 MKLM6_RS14450 f7ff151f6a9f925e2490e7f9a09b213c 723 Pfam PF05226 CHASE2 domain 20 366 9.9E-34 T 28-03-2018 IPR007890 CHASE2 MKLM6_RS14450 f7ff151f6a9f925e2490e7f9a09b213c 723 SMART SM01080 25 371 7.1E-33 T 28-03-2018 IPR007890 CHASE2 MKLM6_RS14450 f7ff151f6a9f925e2490e7f9a09b213c 723 SMART SM00044 431 631 1.0E-4 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MKLM6_RS14450 f7ff151f6a9f925e2490e7f9a09b213c 723 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 480 642 4.9E-21 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MKLM6_RS14450 f7ff151f6a9f925e2490e7f9a09b213c 723 SUPERFAMILY SSF55073 475 652 1.05E-37 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS14450 f7ff151f6a9f925e2490e7f9a09b213c 723 SUPERFAMILY SSF48452 655 706 2.85E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS14450 f7ff151f6a9f925e2490e7f9a09b213c 723 Gene3D G3DSA:1.25.40.10 652 714 1.3E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS14450 f7ff151f6a9f925e2490e7f9a09b213c 723 Gene3D G3DSA:3.30.70.1230 459 651 1.1E-30 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MKLM6_RS06700 2dee41fb472f306c68df1ef2d38ed906 143 Hamap MF_00822 Urease accessory protein UreE [ureE]. 2 138 21.244 T 28-03-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 MKLM6_RS06700 2dee41fb472f306c68df1ef2d38ed906 143 Gene3D G3DSA:2.60.260.20 1 70 4.5E-21 T 28-03-2018 MKLM6_RS06700 2dee41fb472f306c68df1ef2d38ed906 143 Pfam PF05194 UreE urease accessory protein, C-terminal domain 71 143 3.2E-23 T 28-03-2018 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 MKLM6_RS06700 2dee41fb472f306c68df1ef2d38ed906 143 Pfam PF02814 UreE urease accessory protein, N-terminal domain 8 61 6.2E-15 T 28-03-2018 IPR004029 UreE urease accessory, N-terminal MKLM6_RS06700 2dee41fb472f306c68df1ef2d38ed906 143 SUPERFAMILY SSF69737 70 137 1.7E-20 T 28-03-2018 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 MKLM6_RS06700 2dee41fb472f306c68df1ef2d38ed906 143 PIRSF PIRSF036402 1 143 3.1E-40 T 28-03-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 MKLM6_RS06700 2dee41fb472f306c68df1ef2d38ed906 143 SUPERFAMILY SSF69287 1 70 1.44E-14 T 28-03-2018 IPR004029 UreE urease accessory, N-terminal MKLM6_RS06700 2dee41fb472f306c68df1ef2d38ed906 143 Gene3D G3DSA:3.30.70.790 71 143 1.4E-28 T 28-03-2018 MKLM6_RS06700 2dee41fb472f306c68df1ef2d38ed906 143 SMART SM00988 1 64 1.8E-14 T 28-03-2018 IPR004029 UreE urease accessory, N-terminal MKLM6_RS14230 e9222d624ef971ee3623cb9250ebcdf9 122 Pfam PF04343 Protein of unknown function, DUF488 10 116 1.0E-33 T 28-03-2018 IPR007438 Protein of unknown function DUF488 MKLM6_RS19210 fbc4c67bbe3d07e5d9ff13b2998b936a 464 Pfam PF03796 DnaB-like helicase C terminal domain 197 452 3.7E-118 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 MKLM6_RS19210 fbc4c67bbe3d07e5d9ff13b2998b936a 464 Gene3D G3DSA:1.10.860.10 10 161 1.2E-47 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal MKLM6_RS19210 fbc4c67bbe3d07e5d9ff13b2998b936a 464 TIGRFAM TIGR03600 phage_DnaB: phage replicative helicase, DnaB family 22 443 6.7E-151 T 28-03-2018 IPR019889 DNA helicase, DnaB-like, phage MKLM6_RS19210 fbc4c67bbe3d07e5d9ff13b2998b936a 464 SUPERFAMILY SSF48024 17 128 4.84E-38 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 MKLM6_RS19210 fbc4c67bbe3d07e5d9ff13b2998b936a 464 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 19 453 3.7E-182 T 28-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 MKLM6_RS19210 fbc4c67bbe3d07e5d9ff13b2998b936a 464 SUPERFAMILY SSF52540 195 266 1.35E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS19210 fbc4c67bbe3d07e5d9ff13b2998b936a 464 SUPERFAMILY SSF52540 293 446 1.35E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS19210 fbc4c67bbe3d07e5d9ff13b2998b936a 464 Pfam PF00772 DnaB-like helicase N terminal domain 19 120 1.2E-35 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 MKLM6_RS19210 fbc4c67bbe3d07e5d9ff13b2998b936a 464 SMART SM00382 214 412 3.2E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS19210 fbc4c67bbe3d07e5d9ff13b2998b936a 464 Gene3D G3DSA:3.40.50.300 179 459 1.2E-71 T 28-03-2018 MKLM6_RS07195 4a1f3746ef42667c25ce18a7e77ec6da 296 SUPERFAMILY SSF52540 6 198 3.39E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS07195 4a1f3746ef42667c25ce18a7e77ec6da 296 Pfam PF01926 50S ribosome-binding GTPase 6 120 2.3E-22 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS07195 4a1f3746ef42667c25ce18a7e77ec6da 296 Gene3D G3DSA:1.20.120.430 2 61 1.8E-16 T 28-03-2018 MKLM6_RS07195 4a1f3746ef42667c25ce18a7e77ec6da 296 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 158 3.2E-27 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MKLM6_RS07195 4a1f3746ef42667c25ce18a7e77ec6da 296 Gene3D G3DSA:3.40.50.300 62 171 2.8E-11 T 28-03-2018 MKLM6_RS07195 4a1f3746ef42667c25ce18a7e77ec6da 296 Gene3D G3DSA:3.30.300.20 181 294 2.3E-44 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta MKLM6_RS07195 4a1f3746ef42667c25ce18a7e77ec6da 296 Hamap MF_00367 GTPase Era [era]. 1 291 36.177 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS07195 4a1f3746ef42667c25ce18a7e77ec6da 296 TIGRFAM TIGR00436 era: GTP-binding protein Era 4 274 1.5E-91 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS07195 4a1f3746ef42667c25ce18a7e77ec6da 296 SUPERFAMILY SSF54814 177 291 4.45E-42 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 MKLM6_RS07195 4a1f3746ef42667c25ce18a7e77ec6da 296 Pfam PF07650 KH domain 204 279 4.9E-21 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS00920 52e6071d3c5740c462d3628c6b905199 165 Gene3D G3DSA:1.20.120.330 12 136 1.5E-10 T 28-03-2018 MKLM6_RS19860 838da2f1d65e168ce76f8779824cf2d9 414 SUPERFAMILY SSF50939 60 314 1.6E-18 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 MKLM6_RS19860 838da2f1d65e168ce76f8779824cf2d9 414 Gene3D G3DSA:2.120.10.10 35 161 1.3E-12 T 28-03-2018 MKLM6_RS19860 838da2f1d65e168ce76f8779824cf2d9 414 Gene3D G3DSA:2.120.10.10 162 280 7.9E-5 T 28-03-2018 MKLM6_RS19860 838da2f1d65e168ce76f8779824cf2d9 414 Gene3D G3DSA:2.120.10.10 282 413 4.9E-9 T 28-03-2018 MKLM6_RS19860 838da2f1d65e168ce76f8779824cf2d9 414 SUPERFAMILY SSF50939 286 411 5.3E-5 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 MKLM6_RS01645 ca51307846da7457f8a1617fcbab9620 393 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 208 362 3.9E-42 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS01645 ca51307846da7457f8a1617fcbab9620 393 SUPERFAMILY SSF58104 88 388 2.35E-64 T 28-03-2018 MKLM6_RS01645 ca51307846da7457f8a1617fcbab9620 393 Gene3D G3DSA:1.10.287.950 69 162 2.7E-8 T 28-03-2018 MKLM6_RS01645 ca51307846da7457f8a1617fcbab9620 393 SMART SM00283 135 391 1.4E-53 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS01645 ca51307846da7457f8a1617fcbab9620 393 Gene3D G3DSA:1.10.287.950 163 382 4.8E-46 T 28-03-2018 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 329 3.6E-65 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 Gene3D G3DSA:3.30.390.30 336 463 3.5E-34 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 SUPERFAMILY SSF51905 3 339 1.62E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 348 454 4.5E-31 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 Gene3D G3DSA:3.40.50.720 166 335 2.1E-32 T 28-03-2018 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 SUPERFAMILY SSF55424 344 467 6.01E-36 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 PIRSF PIRSF000350 1 469 2.1E-86 T 28-03-2018 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 9 462 3.9E-153 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 43 53 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 294 316 3.2E-40 T 28-03-2018 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 3.2E-40 T 28-03-2018 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 139 157 3.2E-40 T 28-03-2018 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 281 3.2E-40 T 28-03-2018 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 3.2E-40 T 28-03-2018 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 309 316 5.7E-71 T 28-03-2018 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 5.7E-71 T 28-03-2018 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 42 57 5.7E-71 T 28-03-2018 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 5.7E-71 T 28-03-2018 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 5.7E-71 T 28-03-2018 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 5.7E-71 T 28-03-2018 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 280 5.7E-71 T 28-03-2018 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 5.7E-71 T 28-03-2018 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 142 151 5.7E-71 T 28-03-2018 MKLM6_RS00815 1295d2131da2981269749c6d564c9113 471 Gene3D G3DSA:3.50.50.60 2 165 1.2E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS11450 9c254c4d05f3bf543cc94a5481898b53 670 Gene3D G3DSA:2.170.130.10 32 169 5.3E-26 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS11450 9c254c4d05f3bf543cc94a5481898b53 670 Gene3D G3DSA:2.40.170.20 170 670 1.5E-54 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS11450 9c254c4d05f3bf543cc94a5481898b53 670 SUPERFAMILY SSF56935 44 667 2.13E-88 T 28-03-2018 MKLM6_RS11450 9c254c4d05f3bf543cc94a5481898b53 670 Pfam PF07715 TonB-dependent Receptor Plug Domain 55 166 2.0E-18 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS11450 9c254c4d05f3bf543cc94a5481898b53 670 Pfam PF00593 TonB dependent receptor 229 663 2.6E-34 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS19850 e976167357f659eda04f70d8971850a7 428 Pfam PF04250 Protein of unknown function (DUF429) 20 231 1.4E-14 T 28-03-2018 IPR007362 Protein of unknown function DUF429 MKLM6_RS00790 6df7a87fd1979f5a9a93f0075ed41e7d 351 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 143 1.6E-26 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MKLM6_RS00790 6df7a87fd1979f5a9a93f0075ed41e7d 351 Pfam PF00107 Zinc-binding dehydrogenase 185 308 7.2E-23 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MKLM6_RS00790 6df7a87fd1979f5a9a93f0075ed41e7d 351 Gene3D G3DSA:3.40.50.20 191 266 1.0E-16 T 28-03-2018 MKLM6_RS00790 6df7a87fd1979f5a9a93f0075ed41e7d 351 Gene3D G3DSA:3.40.50.20 267 342 5.0E-5 T 28-03-2018 MKLM6_RS00790 6df7a87fd1979f5a9a93f0075ed41e7d 351 SUPERFAMILY SSF51735 148 312 9.12E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS00790 6df7a87fd1979f5a9a93f0075ed41e7d 351 Gene3D G3DSA:3.90.180.10 4 190 2.2E-52 T 28-03-2018 MKLM6_RS00790 6df7a87fd1979f5a9a93f0075ed41e7d 351 SMART SM00829 11 342 2.3E-4 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MKLM6_RS00790 6df7a87fd1979f5a9a93f0075ed41e7d 351 SUPERFAMILY SSF50129 8 170 1.31E-50 T 28-03-2018 IPR011032 GroES-like MKLM6_RS00790 6df7a87fd1979f5a9a93f0075ed41e7d 351 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 178 206 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 MKLM6_RS00790 6df7a87fd1979f5a9a93f0075ed41e7d 351 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MKLM6_RS22105 6dc0b09c35d7ac247f39a19db4e16b4d 301 Gene3D G3DSA:1.20.5.730 110 182 0.001 T 28-03-2018 MKLM6_RS22105 6dc0b09c35d7ac247f39a19db4e16b4d 301 Pfam PF11740 Plasmid replication region DNA-binding N-term 17 142 5.2E-18 T 28-03-2018 IPR021104 KfrA, N-terminal DNA-binding domain MKLM6_RS22105 6dc0b09c35d7ac247f39a19db4e16b4d 301 Gene3D G3DSA:1.20.5.170 247 301 0.02 T 28-03-2018 MKLM6_RS22105 6dc0b09c35d7ac247f39a19db4e16b4d 301 Gene3D G3DSA:1.20.5.170 183 246 0.074 T 28-03-2018 MKLM6_RS05945 5f5bab83f4d6dc4c7a9f0e23570907e5 783 SUPERFAMILY SSF52540 555 736 8.52E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS05945 5f5bab83f4d6dc4c7a9f0e23570907e5 783 Gene3D G3DSA:3.40.50.300 531 750 7.9E-34 T 28-03-2018 MKLM6_RS05945 5f5bab83f4d6dc4c7a9f0e23570907e5 783 Pfam PF02706 Chain length determinant protein 24 117 2.0E-11 T 28-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 MKLM6_RS05945 5f5bab83f4d6dc4c7a9f0e23570907e5 783 Gene3D G3DSA:3.30.1890.10 52 455 2.1E-54 T 28-03-2018 MKLM6_RS05945 5f5bab83f4d6dc4c7a9f0e23570907e5 783 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 536 738 5.4E-37 T 28-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 MKLM6_RS05945 5f5bab83f4d6dc4c7a9f0e23570907e5 783 Pfam PF13614 AAA domain 555 706 1.5E-11 T 28-03-2018 IPR025669 AAA domain MKLM6_RS05945 5f5bab83f4d6dc4c7a9f0e23570907e5 783 Pfam PF13807 G-rich domain on putative tyrosine kinase 399 479 2.3E-28 T 28-03-2018 IPR032807 Tyrosine kinase, G-rich domain MKLM6_RS12900 d5251d30623ba7b7e13c8398f63e56cf 932 Gene3D G3DSA:1.20.1440.90 285 417 4.6E-27 T 28-03-2018 MKLM6_RS12900 d5251d30623ba7b7e13c8398f63e56cf 932 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 415 435 4.1E-57 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MKLM6_RS12900 d5251d30623ba7b7e13c8398f63e56cf 932 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 256 271 4.1E-57 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MKLM6_RS12900 d5251d30623ba7b7e13c8398f63e56cf 932 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 621 650 4.1E-57 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MKLM6_RS12900 d5251d30623ba7b7e13c8398f63e56cf 932 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 757 783 4.1E-57 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MKLM6_RS12900 d5251d30623ba7b7e13c8398f63e56cf 932 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 142 155 4.1E-57 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MKLM6_RS12900 d5251d30623ba7b7e13c8398f63e56cf 932 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 195 211 4.1E-57 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MKLM6_RS12900 d5251d30623ba7b7e13c8398f63e56cf 932 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 579 599 4.1E-57 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MKLM6_RS12900 d5251d30623ba7b7e13c8398f63e56cf 932 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 581 593 - T 28-03-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MKLM6_RS12900 d5251d30623ba7b7e13c8398f63e56cf 932 SUPERFAMILY SSF51621 14 932 3.3E-270 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MKLM6_RS12900 d5251d30623ba7b7e13c8398f63e56cf 932 Pfam PF00311 Phosphoenolpyruvate carboxylase 138 932 1.2E-267 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MKLM6_RS12900 d5251d30623ba7b7e13c8398f63e56cf 932 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 143 154 - T 28-03-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MKLM6_RS12900 d5251d30623ba7b7e13c8398f63e56cf 932 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 3 932 16.656 T 28-03-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MKLM6_RS07225 ce683d59ecd039ae9d345a2f6525a6f9 307 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 132 300 1.2E-49 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS07225 ce683d59ecd039ae9d345a2f6525a6f9 307 Pfam PF00072 Response regulator receiver domain 9 119 3.6E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS07225 ce683d59ecd039ae9d345a2f6525a6f9 307 Gene3D G3DSA:3.30.70.270 135 304 4.9E-53 T 28-03-2018 MKLM6_RS07225 ce683d59ecd039ae9d345a2f6525a6f9 307 SMART SM00448 7 119 1.4E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS07225 ce683d59ecd039ae9d345a2f6525a6f9 307 SUPERFAMILY SSF55073 141 300 2.04E-49 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS07225 ce683d59ecd039ae9d345a2f6525a6f9 307 SMART SM00267 125 301 2.4E-60 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS07225 ce683d59ecd039ae9d345a2f6525a6f9 307 SUPERFAMILY SSF52172 5 127 1.99E-35 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS07225 ce683d59ecd039ae9d345a2f6525a6f9 307 Pfam PF00990 Diguanylate cyclase, GGDEF domain 136 297 3.7E-50 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS07225 ce683d59ecd039ae9d345a2f6525a6f9 307 Gene3D G3DSA:3.40.50.2300 6 134 5.6E-30 T 28-03-2018 MKLM6_RS18365 40319dd0ff10427ed1a1fdd8e232b18f 177 Gene3D G3DSA:3.90.930.12 83 177 2.0E-37 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18365 40319dd0ff10427ed1a1fdd8e232b18f 177 Gene3D G3DSA:3.90.930.12 2 82 1.5E-23 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18365 40319dd0ff10427ed1a1fdd8e232b18f 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 28-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18365 40319dd0ff10427ed1a1fdd8e232b18f 177 SUPERFAMILY SSF56053 2 82 9.03E-21 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18365 40319dd0ff10427ed1a1fdd8e232b18f 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 5.5E-31 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MKLM6_RS18365 40319dd0ff10427ed1a1fdd8e232b18f 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 5.5E-31 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MKLM6_RS18365 40319dd0ff10427ed1a1fdd8e232b18f 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 5.5E-31 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MKLM6_RS18365 40319dd0ff10427ed1a1fdd8e232b18f 177 PIRSF PIRSF002162 1 177 1.2E-43 T 28-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18365 40319dd0ff10427ed1a1fdd8e232b18f 177 SUPERFAMILY SSF56053 83 177 6.02E-34 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18365 40319dd0ff10427ed1a1fdd8e232b18f 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 33.739 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MKLM6_RS18365 40319dd0ff10427ed1a1fdd8e232b18f 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 1.5E-68 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MKLM6_RS18365 40319dd0ff10427ed1a1fdd8e232b18f 177 Pfam PF00347 Ribosomal protein L6 90 163 9.4E-19 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18365 40319dd0ff10427ed1a1fdd8e232b18f 177 Pfam PF00347 Ribosomal protein L6 12 82 1.4E-13 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS07205 886653ddcaa87d42985507870c820d63 247 SUPERFAMILY SSF63892 6 243 2.88E-100 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 MKLM6_RS07205 886653ddcaa87d42985507870c820d63 247 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 8 240 1.7E-103 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 MKLM6_RS07205 886653ddcaa87d42985507870c820d63 247 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 245 127.695 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 MKLM6_RS07205 886653ddcaa87d42985507870c820d63 247 Gene3D G3DSA:3.20.20.70 6 240 2.0E-104 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS07205 886653ddcaa87d42985507870c820d63 247 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 8 241 9.9E-99 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 MKLM6_RS11000 74a726b0cd7cedabe9921c51d8d7180b 462 Gene3D G3DSA:3.30.565.10 302 459 5.6E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS11000 74a726b0cd7cedabe9921c51d8d7180b 462 Pfam PF00512 His Kinase A (phospho-acceptor) domain 199 295 5.9E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS11000 74a726b0cd7cedabe9921c51d8d7180b 462 Gene3D G3DSA:1.10.287.130 186 295 3.8E-12 T 28-03-2018 MKLM6_RS11000 74a726b0cd7cedabe9921c51d8d7180b 462 Gene3D G3DSA:3.40.50.2300 9 163 2.9E-7 T 28-03-2018 MKLM6_RS11000 74a726b0cd7cedabe9921c51d8d7180b 462 SMART SM00387 342 450 6.7E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS11000 74a726b0cd7cedabe9921c51d8d7180b 462 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 428 5.1E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS11000 74a726b0cd7cedabe9921c51d8d7180b 462 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 447 5.1E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS11000 74a726b0cd7cedabe9921c51d8d7180b 462 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 393 5.1E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS11000 74a726b0cd7cedabe9921c51d8d7180b 462 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 407 5.1E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS11000 74a726b0cd7cedabe9921c51d8d7180b 462 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 345 448 3.1E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS11000 74a726b0cd7cedabe9921c51d8d7180b 462 SUPERFAMILY SSF47384 268 296 3.73E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS11000 74a726b0cd7cedabe9921c51d8d7180b 462 SUPERFAMILY SSF47384 193 233 3.73E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS11000 74a726b0cd7cedabe9921c51d8d7180b 462 SUPERFAMILY SSF55874 293 448 1.27E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS00965 361c502b2f1ed686c7b0b7391e03a8d8 288 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 144 161 2.4E-28 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial MKLM6_RS00965 361c502b2f1ed686c7b0b7391e03a8d8 288 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 201 211 2.4E-28 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial MKLM6_RS00965 361c502b2f1ed686c7b0b7391e03a8d8 288 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 224 239 2.4E-28 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial MKLM6_RS00965 361c502b2f1ed686c7b0b7391e03a8d8 288 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 212 223 2.4E-28 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial MKLM6_RS00965 361c502b2f1ed686c7b0b7391e03a8d8 288 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 19 124 4.6E-33 T 28-03-2018 IPR010627 Peptidase A24A, N-terminal MKLM6_RS00965 361c502b2f1ed686c7b0b7391e03a8d8 288 Pfam PF01478 Type IV leader peptidase family 137 244 9.5E-27 T 28-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 MKLM6_RS18755 6663fd14a9901be4f57dcb43b4995617 164 Pfam PF05130 FlgN protein 11 153 1.9E-22 T 28-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 MKLM6_RS18755 6663fd14a9901be4f57dcb43b4995617 164 Gene3D G3DSA:1.20.58.300 10 137 5.9E-16 T 28-03-2018 MKLM6_RS18755 6663fd14a9901be4f57dcb43b4995617 164 SUPERFAMILY SSF140566 12 137 4.45E-16 T 28-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 MKLM6_RS14910 86c87e27ee6eec3c2c013ba1235ad6f3 539 SUPERFAMILY SSF81442 7 532 1.44E-104 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS14910 86c87e27ee6eec3c2c013ba1235ad6f3 539 Gene3D G3DSA:1.20.210.10 3 535 1.9E-78 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS14910 86c87e27ee6eec3c2c013ba1235ad6f3 539 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 9 459 2.2E-83 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS14910 86c87e27ee6eec3c2c013ba1235ad6f3 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 211 232 9.8E-14 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS14910 86c87e27ee6eec3c2c013ba1235ad6f3 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 282 303 9.8E-14 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS14910 86c87e27ee6eec3c2c013ba1235ad6f3 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 411 432 9.8E-14 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS14910 86c87e27ee6eec3c2c013ba1235ad6f3 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 113 125 9.8E-14 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS14910 86c87e27ee6eec3c2c013ba1235ad6f3 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 46 69 9.8E-14 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS01805 f6c4e85776374a96a89100a967fb57a6 575 Gene3D G3DSA:2.60.40.420 150 280 6.3E-25 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS01805 f6c4e85776374a96a89100a967fb57a6 575 SUPERFAMILY SSF49503 331 445 8.57E-15 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS01805 f6c4e85776374a96a89100a967fb57a6 575 SUPERFAMILY SSF49503 160 275 3.49E-28 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS01805 f6c4e85776374a96a89100a967fb57a6 575 Pfam PF07732 Multicopper oxidase 361 409 7.0E-5 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 MKLM6_RS01805 f6c4e85776374a96a89100a967fb57a6 575 Pfam PF07732 Multicopper oxidase 175 273 1.2E-15 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 MKLM6_RS01805 f6c4e85776374a96a89100a967fb57a6 575 Gene3D G3DSA:2.60.40.420 291 458 8.6E-18 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS01085 93086652620d9702519088119e4c41c5 266 SUPERFAMILY SSF53448 2 222 2.44E-44 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS01085 93086652620d9702519088119e4c41c5 266 Gene3D G3DSA:3.90.550.10 3 216 2.4E-36 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS01085 93086652620d9702519088119e4c41c5 266 Pfam PF00535 Glycosyl transferase family 2 4 122 1.5E-23 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MKLM6_RS17995 41fed4ea5058978b9da958dd8b83c0fe 127 Pfam PF04386 Stringent starvation protein B 4 119 1.6E-32 T 28-03-2018 IPR007481 Stringent starvation protein B MKLM6_RS17995 41fed4ea5058978b9da958dd8b83c0fe 127 PIRSF PIRSF005276 1 127 6.7E-48 T 28-03-2018 IPR007481 Stringent starvation protein B MKLM6_RS17995 41fed4ea5058978b9da958dd8b83c0fe 127 SUPERFAMILY SSF101738 1 113 1.18E-43 T 28-03-2018 IPR007481 Stringent starvation protein B MKLM6_RS17995 41fed4ea5058978b9da958dd8b83c0fe 127 Gene3D G3DSA:2.30.30.220 5 102 6.9E-38 T 28-03-2018 IPR007481 Stringent starvation protein B MKLM6_RS21480 869fb63ebf2563f819bc61df2bd78041 302 Hamap MF_00194 Recombination-associated protein RdgC [rdgC]. 1 301 38.421 T 28-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 MKLM6_RS21480 869fb63ebf2563f819bc61df2bd78041 302 Pfam PF04381 Putative exonuclease, RdgC 1 298 3.0E-124 T 28-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 MKLM6_RS13730 485371eb7b58128346b3807a7670f650 150 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 5 142 6.9E-24 T 28-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 MKLM6_RS13730 485371eb7b58128346b3807a7670f650 150 PRINTS PR01004 Flagellar FliJ protein signature 44 61 7.5E-6 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 MKLM6_RS13730 485371eb7b58128346b3807a7670f650 150 PRINTS PR01004 Flagellar FliJ protein signature 126 146 7.5E-6 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 MKLM6_RS13730 485371eb7b58128346b3807a7670f650 150 PRINTS PR01004 Flagellar FliJ protein signature 63 84 7.5E-6 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 MKLM6_RS13730 485371eb7b58128346b3807a7670f650 150 PRINTS PR01004 Flagellar FliJ protein signature 4 26 7.5E-6 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 MKLM6_RS13730 485371eb7b58128346b3807a7670f650 150 PRINTS PR01004 Flagellar FliJ protein signature 86 107 7.5E-6 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 MKLM6_RS13730 485371eb7b58128346b3807a7670f650 150 PIRSF PIRSF019404 1 147 7.4E-29 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 MKLM6_RS13730 485371eb7b58128346b3807a7670f650 150 Pfam PF02050 Flagellar FliJ protein 20 141 5.8E-26 T 28-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 MKLM6_RS08770 c61debaae3b7f9f9eb7e0130ce591597 701 Gene3D G3DSA:2.40.50.140 56 149 5.3E-10 T 28-03-2018 MKLM6_RS08770 c61debaae3b7f9f9eb7e0130ce591597 701 SMART SM00490 513 597 8.9E-21 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS08770 c61debaae3b7f9f9eb7e0130ce591597 701 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 33 669 1.6E-219 T 28-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 MKLM6_RS08770 c61debaae3b7f9f9eb7e0130ce591597 701 SUPERFAMILY SSF50249 14 179 3.86E-34 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS08770 c61debaae3b7f9f9eb7e0130ce591597 701 Gene3D G3DSA:3.40.50.300 259 465 1.2E-35 T 28-03-2018 MKLM6_RS08770 c61debaae3b7f9f9eb7e0130ce591597 701 Pfam PF17191 RecG wedge domain 19 176 1.1E-17 T 28-03-2018 IPR033454 RecG, wedge domain MKLM6_RS08770 c61debaae3b7f9f9eb7e0130ce591597 701 Gene3D G3DSA:3.40.50.300 466 638 1.1E-28 T 28-03-2018 MKLM6_RS08770 c61debaae3b7f9f9eb7e0130ce591597 701 SMART SM00487 274 468 1.2E-29 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MKLM6_RS08770 c61debaae3b7f9f9eb7e0130ce591597 701 Gene3D G3DSA:1.10.150.20 12 55 0.0016 T 28-03-2018 MKLM6_RS08770 c61debaae3b7f9f9eb7e0130ce591597 701 SUPERFAMILY SSF52540 188 462 7.8E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS08770 c61debaae3b7f9f9eb7e0130ce591597 701 Pfam PF00271 Helicase conserved C-terminal domain 488 597 4.3E-16 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS08770 c61debaae3b7f9f9eb7e0130ce591597 701 Pfam PF00270 DEAD/DEAH box helicase 302 440 8.0E-18 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MKLM6_RS08770 c61debaae3b7f9f9eb7e0130ce591597 701 SUPERFAMILY SSF52540 516 660 4.86E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS08770 c61debaae3b7f9f9eb7e0130ce591597 701 SUPERFAMILY SSF52540 301 351 4.86E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS01130 60a063784fca89a5591e5a176f6a258c 525 Pfam PF05036 Sporulation related domain 441 505 9.2E-6 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 MKLM6_RS01130 60a063784fca89a5591e5a176f6a258c 525 SUPERFAMILY SSF52540 40 235 1.23E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS01130 60a063784fca89a5591e5a176f6a258c 525 Pfam PF13401 AAA domain 44 153 8.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS01130 60a063784fca89a5591e5a176f6a258c 525 Gene3D G3DSA:3.40.50.300 26 175 1.8E-9 T 28-03-2018 MKLM6_RS01300 71fe2fde92fac3126b238e5cab0893a0 697 SUPERFAMILY SSF56935 44 690 2.75E-103 T 28-03-2018 MKLM6_RS01300 71fe2fde92fac3126b238e5cab0893a0 697 Pfam PF00593 TonB dependent receptor 248 688 4.5E-41 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS01300 71fe2fde92fac3126b238e5cab0893a0 697 Pfam PF07715 TonB-dependent Receptor Plug Domain 64 169 9.1E-21 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS01300 71fe2fde92fac3126b238e5cab0893a0 697 Gene3D G3DSA:2.40.170.20 178 690 6.4E-63 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS01300 71fe2fde92fac3126b238e5cab0893a0 697 Gene3D G3DSA:2.170.130.10 39 177 2.7E-28 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS19660 a7cfa4961d497c9f33bb1dd247a422b4 475 Gene3D G3DSA:1.10.3210.10 5 289 5.4E-27 T 28-03-2018 MKLM6_RS19660 a7cfa4961d497c9f33bb1dd247a422b4 475 Pfam PF01590 GAF domain 326 465 9.2E-6 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS19660 a7cfa4961d497c9f33bb1dd247a422b4 475 SUPERFAMILY SSF55781 310 468 3.05E-14 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS19660 a7cfa4961d497c9f33bb1dd247a422b4 475 Pfam PF08668 HDOD domain 23 213 1.3E-36 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD MKLM6_RS19660 a7cfa4961d497c9f33bb1dd247a422b4 475 SUPERFAMILY SSF109604 16 268 4.11E-43 T 28-03-2018 MKLM6_RS19660 a7cfa4961d497c9f33bb1dd247a422b4 475 Gene3D G3DSA:3.30.450.40 304 469 8.4E-13 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS01670 9bb3cf406f564f5f3f6ccd7523d435bb 222 Gene3D G3DSA:1.10.10.60 1 53 3.3E-20 T 28-03-2018 MKLM6_RS01670 9bb3cf406f564f5f3f6ccd7523d435bb 222 Gene3D G3DSA:1.10.357.10 54 216 2.9E-37 T 28-03-2018 MKLM6_RS01670 9bb3cf406f564f5f3f6ccd7523d435bb 222 SUPERFAMILY SSF48498 83 207 6.67E-12 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MKLM6_RS01670 9bb3cf406f564f5f3f6ccd7523d435bb 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 4.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MKLM6_RS01670 9bb3cf406f564f5f3f6ccd7523d435bb 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 4.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MKLM6_RS01670 9bb3cf406f564f5f3f6ccd7523d435bb 222 SUPERFAMILY SSF46689 10 70 7.18E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS01670 9bb3cf406f564f5f3f6ccd7523d435bb 222 Pfam PF09209 Domain of unknown function (DUF1956) 88 202 1.7E-20 T 28-03-2018 IPR015292 Transcription regulator YbiH, C-terminal MKLM6_RS01670 9bb3cf406f564f5f3f6ccd7523d435bb 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 4.1E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MKLM6_RS12135 e85040dfa00304f0c5730d641a51ef3f 333 PIRSF PIRSF000294 6 332 4.1E-108 T 28-03-2018 IPR026259 Di-c-type haem protein, MauG/cytochrome c peroxidase GO:0016491|GO:0020037|GO:0055114 MKLM6_RS12135 e85040dfa00304f0c5730d641a51ef3f 333 Pfam PF03150 Di-haem cytochrome c peroxidase 40 188 9.1E-56 T 28-03-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 MKLM6_RS12135 e85040dfa00304f0c5730d641a51ef3f 333 SUPERFAMILY SSF46626 21 176 2.56E-53 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS12135 e85040dfa00304f0c5730d641a51ef3f 333 Pfam PF00034 Cytochrome c 201 312 1.7E-5 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS12135 e85040dfa00304f0c5730d641a51ef3f 333 SUPERFAMILY SSF46626 175 325 2.83E-35 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS12135 e85040dfa00304f0c5730d641a51ef3f 333 Gene3D G3DSA:1.10.760.10 28 196 9.7E-51 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS12135 e85040dfa00304f0c5730d641a51ef3f 333 Gene3D G3DSA:1.10.760.10 200 326 1.1E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS09325 ceb82926a6c252822aa309a203d5c7e5 317 Gene3D G3DSA:3.40.630.30 149 307 2.1E-20 T 28-03-2018 MKLM6_RS09325 ceb82926a6c252822aa309a203d5c7e5 317 Gene3D G3DSA:3.40.630.30 7 130 5.3E-4 T 28-03-2018 MKLM6_RS09325 ceb82926a6c252822aa309a203d5c7e5 317 SUPERFAMILY SSF55729 158 305 7.42E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS09325 ceb82926a6c252822aa309a203d5c7e5 317 Pfam PF13480 Acetyltransferase (GNAT) domain 162 286 2.4E-10 T 28-03-2018 MKLM6_RS19905 1eefa377c12587dc405064b996024b42 478 Gene3D G3DSA:1.10.10.10 323 413 1.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS19905 1eefa377c12587dc405064b996024b42 478 PRINTS PR00045 Sigma-54 factor signature 451 469 3.9E-28 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS19905 1eefa377c12587dc405064b996024b42 478 PRINTS PR00045 Sigma-54 factor signature 187 204 3.9E-28 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS19905 1eefa377c12587dc405064b996024b42 478 PRINTS PR00045 Sigma-54 factor signature 377 389 3.9E-28 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS19905 1eefa377c12587dc405064b996024b42 478 PRINTS PR00045 Sigma-54 factor signature 393 404 3.9E-28 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS19905 1eefa377c12587dc405064b996024b42 478 Pfam PF04552 Sigma-54, DNA binding domain 320 476 6.9E-69 T 28-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding MKLM6_RS19905 1eefa377c12587dc405064b996024b42 478 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 456 463 - T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS19905 1eefa377c12587dc405064b996024b42 478 Pfam PF04963 Sigma-54 factor, core binding domain 109 304 1.6E-55 T 28-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 MKLM6_RS19905 1eefa377c12587dc405064b996024b42 478 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 365 384 - T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS19905 1eefa377c12587dc405064b996024b42 478 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 10 475 1.8E-148 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS19905 1eefa377c12587dc405064b996024b42 478 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 4 49 2.1E-15 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS19905 1eefa377c12587dc405064b996024b42 478 PIRSF PIRSF000774 1 478 9.2E-155 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS17000 879d58ef73d2fc78f481d7ebad3a9b27 161 Gene3D G3DSA:3.40.30.10 13 159 2.5E-11 T 28-03-2018 MKLM6_RS17000 879d58ef73d2fc78f481d7ebad3a9b27 161 SUPERFAMILY SSF52833 5 156 1.62E-11 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS16495 8e725b2973593154544638a163d71480 245 Pfam PF01895 PhoU domain 136 218 2.9E-7 T 28-03-2018 IPR026022 PhoU domain MKLM6_RS16495 8e725b2973593154544638a163d71480 245 Pfam PF01895 PhoU domain 30 115 1.2E-11 T 28-03-2018 IPR026022 PhoU domain MKLM6_RS16495 8e725b2973593154544638a163d71480 245 Gene3D G3DSA:1.20.58.220 9 121 5.2E-15 T 28-03-2018 MKLM6_RS16495 8e725b2973593154544638a163d71480 245 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 16 227 4.3E-42 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 MKLM6_RS16495 8e725b2973593154544638a163d71480 245 Gene3D G3DSA:1.20.58.220 123 235 8.0E-14 T 28-03-2018 MKLM6_RS16495 8e725b2973593154544638a163d71480 245 SUPERFAMILY SSF109755 16 232 3.66E-40 T 28-03-2018 MKLM6_RS12605 e35581ea190129a747fab53f3db2d1a3 1125 SUPERFAMILY SSF82689 1012 1111 1.09E-26 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MKLM6_RS12605 e35581ea190129a747fab53f3db2d1a3 1125 Gene3D G3DSA:2.30.30.60 960 1009 1.0E-12 T 28-03-2018 MKLM6_RS12605 e35581ea190129a747fab53f3db2d1a3 1125 Gene3D G3DSA:3.30.70.100 1012 1106 5.8E-22 T 28-03-2018 MKLM6_RS12605 e35581ea190129a747fab53f3db2d1a3 1125 Pfam PF12794 Mechanosensitive ion channel inner membrane domain 1 510 841 9.1E-77 T 28-03-2018 IPR025692 Mechanosensitive ion channel inner membrane domain 1 MKLM6_RS12605 e35581ea190129a747fab53f3db2d1a3 1125 Pfam PF12795 Mechanosensitive ion channel porin domain 46 282 2.8E-20 T 28-03-2018 IPR024393 Mechanosensitive ion channel MscS, porin domain MKLM6_RS12605 e35581ea190129a747fab53f3db2d1a3 1125 SUPERFAMILY SSF50182 945 1010 6.54E-17 T 28-03-2018 IPR010920 LSM domain MKLM6_RS12605 e35581ea190129a747fab53f3db2d1a3 1125 Pfam PF00924 Mechanosensitive ion channel 902 1101 3.8E-51 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MKLM6_RS14755 7e6147d0ff79f81c1cb97b0a53b23465 434 Gene3D G3DSA:3.40.50.300 1 224 4.0E-62 T 28-03-2018 MKLM6_RS14755 7e6147d0ff79f81c1cb97b0a53b23465 434 SUPERFAMILY SSF52540 74 360 1.49E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS14755 7e6147d0ff79f81c1cb97b0a53b23465 434 SMART SM00490 258 339 1.6E-31 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS14755 7e6147d0ff79f81c1cb97b0a53b23465 434 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 153 161 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MKLM6_RS14755 7e6147d0ff79f81c1cb97b0a53b23465 434 Gene3D G3DSA:3.40.50.300 225 429 5.3E-44 T 28-03-2018 MKLM6_RS14755 7e6147d0ff79f81c1cb97b0a53b23465 434 SMART SM00487 20 222 2.1E-62 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MKLM6_RS14755 7e6147d0ff79f81c1cb97b0a53b23465 434 Pfam PF00270 DEAD/DEAH box helicase 25 190 4.1E-50 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MKLM6_RS14755 7e6147d0ff79f81c1cb97b0a53b23465 434 Pfam PF00271 Helicase conserved C-terminal domain 238 339 6.8E-27 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS21385 2e6cab7daf4914da6170760a4fdd636d 242 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 19 239 5.1E-73 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase MKLM6_RS21385 2e6cab7daf4914da6170760a4fdd636d 242 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 28 240 1.2E-58 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase MKLM6_RS21385 2e6cab7daf4914da6170760a4fdd636d 242 SUPERFAMILY SSF64438 2 240 2.2E-82 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic MKLM6_RS21385 2e6cab7daf4914da6170760a4fdd636d 242 Gene3D G3DSA:3.60.140.10 1 242 1.4E-90 T 28-03-2018 MKLM6_RS13515 b5a5099b5803c47ee7f6056401ff8a38 335 Gene3D G3DSA:3.40.50.720 2 189 7.3E-37 T 28-03-2018 MKLM6_RS13515 b5a5099b5803c47ee7f6056401ff8a38 335 PRINTS PR01713 Nucleotide sugar epimerase signature 216 231 8.5E-29 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 MKLM6_RS13515 b5a5099b5803c47ee7f6056401ff8a38 335 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 8.5E-29 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 MKLM6_RS13515 b5a5099b5803c47ee7f6056401ff8a38 335 PRINTS PR01713 Nucleotide sugar epimerase signature 256 271 8.5E-29 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 MKLM6_RS13515 b5a5099b5803c47ee7f6056401ff8a38 335 PRINTS PR01713 Nucleotide sugar epimerase signature 295 312 8.5E-29 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 MKLM6_RS13515 b5a5099b5803c47ee7f6056401ff8a38 335 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 238 4.8E-56 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MKLM6_RS13515 b5a5099b5803c47ee7f6056401ff8a38 335 SUPERFAMILY SSF51735 1 333 5.52E-92 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS13515 b5a5099b5803c47ee7f6056401ff8a38 335 Gene3D G3DSA:3.90.25.10 190 335 6.6E-37 T 28-03-2018 MKLM6_RS10305 38406110776b8f8bf66294182ad57fd8 122 Pfam PF00072 Response regulator receiver domain 5 116 1.6E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS10305 38406110776b8f8bf66294182ad57fd8 122 SUPERFAMILY SSF52172 3 120 4.27E-35 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS10305 38406110776b8f8bf66294182ad57fd8 122 Gene3D G3DSA:3.40.50.2300 1 121 2.0E-34 T 28-03-2018 MKLM6_RS10305 38406110776b8f8bf66294182ad57fd8 122 SMART SM00448 3 116 2.3E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS16765 37402f56f4b48d9b17935f0ae12ec7b4 664 Pfam PF00005 ABC transporter 26 185 1.5E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS16765 37402f56f4b48d9b17935f0ae12ec7b4 664 Pfam PF00005 ABC transporter 432 584 3.1E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS16765 37402f56f4b48d9b17935f0ae12ec7b4 664 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS16765 37402f56f4b48d9b17935f0ae12ec7b4 664 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 635 662 0.0044 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MKLM6_RS16765 37402f56f4b48d9b17935f0ae12ec7b4 664 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 267 1.7E-5 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MKLM6_RS16765 37402f56f4b48d9b17935f0ae12ec7b4 664 ProSitePatterns PS00211 ABC transporters family signature. 556 570 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS16765 37402f56f4b48d9b17935f0ae12ec7b4 664 SUPERFAMILY SSF52540 404 655 2.21E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS16765 37402f56f4b48d9b17935f0ae12ec7b4 664 SMART SM00382 440 633 5.5E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS16765 37402f56f4b48d9b17935f0ae12ec7b4 664 SMART SM00382 34 250 1.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS16765 37402f56f4b48d9b17935f0ae12ec7b4 664 SUPERFAMILY SSF52540 5 257 2.6E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS16765 37402f56f4b48d9b17935f0ae12ec7b4 664 Gene3D G3DSA:3.40.50.300 2 349 3.1E-67 T 28-03-2018 MKLM6_RS16765 37402f56f4b48d9b17935f0ae12ec7b4 664 Gene3D G3DSA:3.40.50.300 401 663 1.6E-72 T 28-03-2018 MKLM6_RS11360 f4d763ab6e7904fdef8d1a365c59d0ad 137 Gene3D G3DSA:3.30.1300.30 31 136 3.0E-5 T 28-03-2018 MKLM6_RS11360 f4d763ab6e7904fdef8d1a365c59d0ad 137 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 27 4.2E-5 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS11360 f4d763ab6e7904fdef8d1a365c59d0ad 137 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 27 1.7E-7 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS11360 f4d763ab6e7904fdef8d1a365c59d0ad 137 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS04860 ecb11eaed59c33f6ac23a83171da2216 163 SUPERFAMILY SSF50447 2 87 2.12E-22 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain MKLM6_RS04860 ecb11eaed59c33f6ac23a83171da2216 163 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 1 163 20.564 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 MKLM6_RS04860 ecb11eaed59c33f6ac23a83171da2216 163 Pfam PF05239 PRC-barrel domain 91 149 8.9E-6 T 28-03-2018 IPR027275 PRC-barrel domain MKLM6_RS04860 ecb11eaed59c33f6ac23a83171da2216 163 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 1 162 1.1E-49 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 MKLM6_RS04860 ecb11eaed59c33f6ac23a83171da2216 163 Pfam PF01782 RimM N-terminal domain 3 83 1.2E-23 T 28-03-2018 IPR002676 RimM protein GO:0006364 MKLM6_RS04860 ecb11eaed59c33f6ac23a83171da2216 163 Gene3D G3DSA:2.30.30.240 89 158 8.5E-20 T 28-03-2018 MKLM6_RS04860 ecb11eaed59c33f6ac23a83171da2216 163 Gene3D G3DSA:2.40.30.60 1 87 3.1E-22 T 28-03-2018 IPR002676 RimM protein GO:0006364 MKLM6_RS04860 ecb11eaed59c33f6ac23a83171da2216 163 SUPERFAMILY SSF50346 93 163 1.16E-17 T 28-03-2018 IPR011033 PRC-barrel-like MKLM6_RS21500 ef3a07c24639744853f3e90298f80eb7 343 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 35 334 4.3E-65 T 28-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 MKLM6_RS21500 ef3a07c24639744853f3e90298f80eb7 343 Gene3D G3DSA:1.10.1040.10 211 343 1.6E-39 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MKLM6_RS21500 ef3a07c24639744853f3e90298f80eb7 343 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 211 332 4.3E-29 T 28-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 MKLM6_RS21500 ef3a07c24639744853f3e90298f80eb7 343 Gene3D G3DSA:3.40.50.720 27 210 1.6E-25 T 28-03-2018 MKLM6_RS21500 ef3a07c24639744853f3e90298f80eb7 343 SUPERFAMILY SSF51735 35 191 4.04E-10 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS21500 ef3a07c24639744853f3e90298f80eb7 343 SUPERFAMILY SSF48179 211 333 3.74E-31 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MKLM6_RS21500 ef3a07c24639744853f3e90298f80eb7 343 Pfam PF02558 Ketopantoate reductase PanE/ApbA 36 184 1.3E-30 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 MKLM6_RS18915 cc61f792a7de5ef349db818f424087c4 188 Pfam PF00692 dUTPase 76 184 6.1E-7 T 28-03-2018 IPR029054 dUTPase-like MKLM6_RS18915 cc61f792a7de5ef349db818f424087c4 188 Gene3D G3DSA:2.70.40.10 1 161 4.6E-61 T 28-03-2018 MKLM6_RS18915 cc61f792a7de5ef349db818f424087c4 188 Hamap MF_00146 dCTP deaminase [dcd]. 1 188 28.262 T 28-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 MKLM6_RS18915 cc61f792a7de5ef349db818f424087c4 188 SUPERFAMILY SSF51283 3 187 5.37E-53 T 28-03-2018 IPR029054 dUTPase-like MKLM6_RS18915 cc61f792a7de5ef349db818f424087c4 188 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 4 187 8.3E-50 T 28-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 MKLM6_RS09420 6758ea6fca62063982ec784fe2734783 285 Gene3D G3DSA:3.40.50.720 109 224 7.4E-10 T 28-03-2018 MKLM6_RS09420 6758ea6fca62063982ec784fe2734783 285 SUPERFAMILY SSF51735 110 222 3.73E-13 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS09420 6758ea6fca62063982ec784fe2734783 285 Gene3D G3DSA:3.40.50.10280 2 108 4.6E-46 T 28-03-2018 IPR015259 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal MKLM6_RS09420 6758ea6fca62063982ec784fe2734783 285 SUPERFAMILY SSF53223 1 96 7.19E-36 T 28-03-2018 MKLM6_RS09420 6758ea6fca62063982ec784fe2734783 285 Pfam PF09176 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal 16 96 1.1E-32 T 28-03-2018 IPR015259 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal MKLM6_RS18500 6ceda88c15b269fe72c9894a97af21d3 177 Pfam PF00467 KOW motif 126 158 2.0E-7 T 28-03-2018 IPR005824 KOW MKLM6_RS18500 6ceda88c15b269fe72c9894a97af21d3 177 SUPERFAMILY SSF82679 4 113 2.22E-38 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MKLM6_RS18500 6ceda88c15b269fe72c9894a97af21d3 177 Gene3D G3DSA:2.30.30.30 118 177 4.3E-21 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 MKLM6_RS18500 6ceda88c15b269fe72c9894a97af21d3 177 SMART SM00739 123 150 6.2E-7 T 28-03-2018 IPR005824 KOW MKLM6_RS18500 6ceda88c15b269fe72c9894a97af21d3 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 28-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site MKLM6_RS18500 6ceda88c15b269fe72c9894a97af21d3 177 Gene3D G3DSA:3.30.70.940 2 115 1.8E-42 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MKLM6_RS18500 6ceda88c15b269fe72c9894a97af21d3 177 Pfam PF02357 Transcription termination factor nusG 4 107 2.5E-27 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MKLM6_RS18500 6ceda88c15b269fe72c9894a97af21d3 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 177 5.1E-69 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MKLM6_RS18500 6ceda88c15b269fe72c9894a97af21d3 177 SMART SM00738 2 111 6.9E-46 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MKLM6_RS18500 6ceda88c15b269fe72c9894a97af21d3 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 2.3E-19 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MKLM6_RS18500 6ceda88c15b269fe72c9894a97af21d3 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 2.3E-19 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MKLM6_RS18500 6ceda88c15b269fe72c9894a97af21d3 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 2.3E-19 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MKLM6_RS18500 6ceda88c15b269fe72c9894a97af21d3 177 SUPERFAMILY SSF50104 121 177 1.2E-19 T 28-03-2018 IPR008991 Translation protein SH3-like domain MKLM6_RS18500 6ceda88c15b269fe72c9894a97af21d3 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 25.502 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MKLM6_RS06815 1198939bbd46d3a6416804600f1d0f63 180 SUPERFAMILY SSF143422 1 143 6.28E-35 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS06815 1198939bbd46d3a6416804600f1d0f63 180 SMART SM01321 9 137 2.0E-33 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS06815 1198939bbd46d3a6416804600f1d0f63 180 Pfam PF01797 Transposase IS200 like 12 136 1.8E-9 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS06815 1198939bbd46d3a6416804600f1d0f63 180 Gene3D G3DSA:3.30.70.1290 1 143 8.8E-34 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS19965 9bffe7c95f88ac46d6e3e41ba1b4373d 433 PRINTS PR00083 Histidinol dehydrogenase signature 367 385 8.8E-87 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MKLM6_RS19965 9bffe7c95f88ac46d6e3e41ba1b4373d 433 PRINTS PR00083 Histidinol dehydrogenase signature 38 62 8.8E-87 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MKLM6_RS19965 9bffe7c95f88ac46d6e3e41ba1b4373d 433 PRINTS PR00083 Histidinol dehydrogenase signature 235 256 8.8E-87 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MKLM6_RS19965 9bffe7c95f88ac46d6e3e41ba1b4373d 433 PRINTS PR00083 Histidinol dehydrogenase signature 257 276 8.8E-87 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MKLM6_RS19965 9bffe7c95f88ac46d6e3e41ba1b4373d 433 PRINTS PR00083 Histidinol dehydrogenase signature 326 351 8.8E-87 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MKLM6_RS19965 9bffe7c95f88ac46d6e3e41ba1b4373d 433 PRINTS PR00083 Histidinol dehydrogenase signature 176 202 8.8E-87 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MKLM6_RS19965 9bffe7c95f88ac46d6e3e41ba1b4373d 433 PRINTS PR00083 Histidinol dehydrogenase signature 206 231 8.8E-87 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MKLM6_RS19965 9bffe7c95f88ac46d6e3e41ba1b4373d 433 PRINTS PR00083 Histidinol dehydrogenase signature 142 168 8.8E-87 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MKLM6_RS19965 9bffe7c95f88ac46d6e3e41ba1b4373d 433 SUPERFAMILY SSF53720 35 432 7.26E-85 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MKLM6_RS19965 9bffe7c95f88ac46d6e3e41ba1b4373d 433 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 38 432 1.5E-157 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MKLM6_RS19965 9bffe7c95f88ac46d6e3e41ba1b4373d 433 Gene3D G3DSA:3.40.50.1980 31 231 1.4E-85 T 28-03-2018 MKLM6_RS19965 9bffe7c95f88ac46d6e3e41ba1b4373d 433 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 10 433 39.938 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MKLM6_RS19965 9bffe7c95f88ac46d6e3e41ba1b4373d 433 Pfam PF00815 Histidinol dehydrogenase 30 432 3.0E-164 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MKLM6_RS19965 9bffe7c95f88ac46d6e3e41ba1b4373d 433 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 235 267 - T 28-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 MKLM6_RS19965 9bffe7c95f88ac46d6e3e41ba1b4373d 433 Gene3D G3DSA:3.40.50.1980 232 377 1.6E-67 T 28-03-2018 MKLM6_RS19965 9bffe7c95f88ac46d6e3e41ba1b4373d 433 PIRSF PIRSF000099 1 433 8.8E-154 T 28-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MKLM6_RS03455 f2a945dd2dbbd65203f364cb99f5a060 540 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MKLM6_RS03455 f2a945dd2dbbd65203f364cb99f5a060 540 Hamap MF_00600 60 kDa chaperonin [groL]. 2 537 41.22 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MKLM6_RS03455 f2a945dd2dbbd65203f364cb99f5a060 540 SUPERFAMILY SSF54849 137 203 3.2E-24 T 28-03-2018 MKLM6_RS03455 f2a945dd2dbbd65203f364cb99f5a060 540 Gene3D G3DSA:1.10.560.10 1 185 1.0E-42 T 28-03-2018 IPR027413 GroEL-like equatorial domain MKLM6_RS03455 f2a945dd2dbbd65203f364cb99f5a060 540 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 522 1.8E-98 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 MKLM6_RS03455 f2a945dd2dbbd65203f364cb99f5a060 540 SUPERFAMILY SSF48592 406 521 3.66E-77 T 28-03-2018 MKLM6_RS03455 f2a945dd2dbbd65203f364cb99f5a060 540 SUPERFAMILY SSF48592 7 134 3.66E-77 T 28-03-2018 MKLM6_RS03455 f2a945dd2dbbd65203f364cb99f5a060 540 Gene3D G3DSA:1.10.560.10 374 516 1.4E-25 T 28-03-2018 IPR027413 GroEL-like equatorial domain MKLM6_RS03455 f2a945dd2dbbd65203f364cb99f5a060 540 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 526 3.4E-258 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MKLM6_RS03455 f2a945dd2dbbd65203f364cb99f5a060 540 SUPERFAMILY SSF52029 185 376 3.66E-84 T 28-03-2018 IPR027409 GroEL-like apical domain MKLM6_RS03455 f2a945dd2dbbd65203f364cb99f5a060 540 PRINTS PR00298 60kDa chaperonin signature 398 419 3.3E-74 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MKLM6_RS03455 f2a945dd2dbbd65203f364cb99f5a060 540 PRINTS PR00298 60kDa chaperonin signature 83 110 3.3E-74 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MKLM6_RS03455 f2a945dd2dbbd65203f364cb99f5a060 540 PRINTS PR00298 60kDa chaperonin signature 268 291 3.3E-74 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MKLM6_RS03455 f2a945dd2dbbd65203f364cb99f5a060 540 PRINTS PR00298 60kDa chaperonin signature 27 53 3.3E-74 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MKLM6_RS03455 f2a945dd2dbbd65203f364cb99f5a060 540 PRINTS PR00298 60kDa chaperonin signature 350 375 3.3E-74 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MKLM6_RS03455 f2a945dd2dbbd65203f364cb99f5a060 540 Gene3D G3DSA:3.50.7.10 186 373 4.1E-99 T 28-03-2018 IPR027409 GroEL-like apical domain MKLM6_RS02435 f31fba3a076a1559334dd519a9fad72c 267 SUPERFAMILY SSF46565 198 262 3.44E-18 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS02435 f31fba3a076a1559334dd519a9fad72c 267 Gene3D G3DSA:1.10.3680.10 30 177 6.6E-29 T 28-03-2018 IPR029024 TerB-like MKLM6_RS02435 f31fba3a076a1559334dd519a9fad72c 267 Gene3D G3DSA:1.10.287.110 178 265 2.6E-18 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS02435 f31fba3a076a1559334dd519a9fad72c 267 Pfam PF05099 Tellurite resistance protein TerB 36 171 1.3E-21 T 28-03-2018 IPR007791 Co-chaperone DjlA, N-terminal MKLM6_RS02435 f31fba3a076a1559334dd519a9fad72c 267 PRINTS PR00625 DnaJ domain signature 222 237 4.2E-11 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS02435 f31fba3a076a1559334dd519a9fad72c 267 PRINTS PR00625 DnaJ domain signature 246 266 4.2E-11 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS02435 f31fba3a076a1559334dd519a9fad72c 267 PRINTS PR00625 DnaJ domain signature 204 222 4.2E-11 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS02435 f31fba3a076a1559334dd519a9fad72c 267 Hamap MF_01153 Co-chaperone protein DjlA [djlA]. 3 267 37.724 T 28-03-2018 IPR023749 Co-chaperone DjlA GO:0051087 MKLM6_RS02435 f31fba3a076a1559334dd519a9fad72c 267 SMART SM00271 201 266 5.2E-20 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS02435 f31fba3a076a1559334dd519a9fad72c 267 SUPERFAMILY SSF158682 48 214 5.75E-30 T 28-03-2018 MKLM6_RS02435 f31fba3a076a1559334dd519a9fad72c 267 SUPERFAMILY SSF158682 5 21 5.75E-30 T 28-03-2018 MKLM6_RS02435 f31fba3a076a1559334dd519a9fad72c 267 Pfam PF00226 DnaJ domain 202 263 1.9E-13 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS16030 5494d964f4173432cac78e9234ba0de3 1111 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 3 1100 0.0 T 28-03-2018 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 MKLM6_RS16030 5494d964f4173432cac78e9234ba0de3 1111 SUPERFAMILY SSF53223 283 453 9.35E-24 T 28-03-2018 MKLM6_RS16030 5494d964f4173432cac78e9234ba0de3 1111 Gene3D G3DSA:3.40.50.720 451 757 6.2E-43 T 28-03-2018 MKLM6_RS16030 5494d964f4173432cac78e9234ba0de3 1111 Gene3D G3DSA:3.40.50.10860 309 447 4.8E-6 T 28-03-2018 MKLM6_RS16030 5494d964f4173432cac78e9234ba0de3 1111 SUPERFAMILY SSF51735 597 698 7.88E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS16030 5494d964f4173432cac78e9234ba0de3 1111 SUPERFAMILY SSF51735 458 561 7.88E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS04585 c4026c9890446dcb80ce9cbf8bdc742d 174 Gene3D G3DSA:1.25.40.10 11 168 7.6E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS21550 82d37df8fc4f00a4bb8d564e4ca2151d 206 SUPERFAMILY SSF53335 10 192 2.63E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS21550 82d37df8fc4f00a4bb8d564e4ca2151d 206 Gene3D G3DSA:3.40.50.150 2 194 1.7E-29 T 28-03-2018 MKLM6_RS21550 82d37df8fc4f00a4bb8d564e4ca2151d 206 Pfam PF08241 Methyltransferase domain 49 142 6.3E-25 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MKLM6_RS18120 42cd7b394f979c529bd5bc5167a3ac49 249 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 248 39.537 T 28-03-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 MKLM6_RS18120 42cd7b394f979c529bd5bc5167a3ac49 249 SUPERFAMILY SSF64167 1 245 2.62E-83 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 MKLM6_RS18120 42cd7b394f979c529bd5bc5167a3ac49 249 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 233 5.2E-69 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 MKLM6_RS18120 42cd7b394f979c529bd5bc5167a3ac49 249 Pfam PF01975 Survival protein SurE 3 182 2.9E-59 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 MKLM6_RS18120 42cd7b394f979c529bd5bc5167a3ac49 249 Gene3D G3DSA:3.40.1210.10 1 248 1.4E-86 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 MKLM6_RS16435 3022703e9aa905c16145f98e149d1cf1 301 SUPERFAMILY SSF51735 115 232 3.86E-10 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS16435 3022703e9aa905c16145f98e149d1cf1 301 SUPERFAMILY SSF53223 4 98 5.47E-36 T 28-03-2018 MKLM6_RS16435 3022703e9aa905c16145f98e149d1cf1 301 Pfam PF09176 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal 18 98 4.5E-35 T 28-03-2018 IPR015259 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal MKLM6_RS16435 3022703e9aa905c16145f98e149d1cf1 301 Gene3D G3DSA:3.40.50.10280 4 113 2.5E-50 T 28-03-2018 IPR015259 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal MKLM6_RS16435 3022703e9aa905c16145f98e149d1cf1 301 Gene3D G3DSA:3.40.50.720 114 272 5.2E-8 T 28-03-2018 MKLM6_RS19680 b2c1464e78a1e550422106895f615a4f 183 Gene3D G3DSA:2.40.33.20 8 181 5.0E-27 T 28-03-2018 MKLM6_RS19680 b2c1464e78a1e550422106895f615a4f 183 SUPERFAMILY SSF50800 12 169 3.3E-27 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain MKLM6_RS19680 b2c1464e78a1e550422106895f615a4f 183 Pfam PF03473 MOSC domain 57 167 2.2E-5 T 28-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 MKLM6_RS08530 da4e978f919affc83f599b3ace547f1d 177 SMART SM01321 9 143 2.4E-6 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS08530 da4e978f919affc83f599b3ace547f1d 177 Gene3D G3DSA:3.30.70.1290 1 149 6.1E-23 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS08530 da4e978f919affc83f599b3ace547f1d 177 SUPERFAMILY SSF143422 5 149 3.14E-18 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS06410 df9f31ca89590470c8830ffa15ae9570 672 SMART SM00487 1 151 0.0061 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MKLM6_RS06410 df9f31ca89590470c8830ffa15ae9570 672 Pfam PF00271 Helicase conserved C-terminal domain 267 374 3.9E-20 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS06410 df9f31ca89590470c8830ffa15ae9570 672 Gene3D G3DSA:3.40.50.300 254 412 6.7E-36 T 28-03-2018 MKLM6_RS06410 df9f31ca89590470c8830ffa15ae9570 672 SUPERFAMILY SSF52540 83 137 2.46E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS06410 df9f31ca89590470c8830ffa15ae9570 672 SUPERFAMILY SSF52540 252 412 2.46E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS06410 df9f31ca89590470c8830ffa15ae9570 672 Pfam PF00176 SNF2 family N-terminal domain 19 252 4.7E-27 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 MKLM6_RS06410 df9f31ca89590470c8830ffa15ae9570 672 Gene3D G3DSA:3.40.50.10810 1 181 2.3E-29 T 28-03-2018 MKLM6_RS06410 df9f31ca89590470c8830ffa15ae9570 672 SMART SM00490 292 374 9.9E-24 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS06410 df9f31ca89590470c8830ffa15ae9570 672 SUPERFAMILY SSF52540 2 180 1.77E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS03360 aa99b7a8b3d65820035ddc7b7a505d30 160 Pfam PF05117 Family of unknown function (DUF695) 25 154 5.8E-17 T 28-03-2018 IPR016097 Domain of unknown function DUF695 MKLM6_RS18970 f66039ac7bd6377796545b9c5abfe055 305 Gene3D G3DSA:3.90.550.10 2 279 2.2E-53 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS18970 f66039ac7bd6377796545b9c5abfe055 305 Pfam PF00535 Glycosyl transferase family 2 7 166 1.3E-36 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MKLM6_RS18970 f66039ac7bd6377796545b9c5abfe055 305 SUPERFAMILY SSF53448 5 225 1.07E-62 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS19105 f8e14b914f43e044681587ddfb0babd0 628 SUPERFAMILY SSF49503 196 311 1.47E-27 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS19105 f8e14b914f43e044681587ddfb0babd0 628 SUPERFAMILY SSF49503 84 192 1.53E-25 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS19105 f8e14b914f43e044681587ddfb0babd0 628 Pfam PF07731 Multicopper oxidase 541 627 2.9E-19 T 28-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 MKLM6_RS19105 f8e14b914f43e044681587ddfb0babd0 628 Pfam PF07732 Multicopper oxidase 83 191 1.2E-23 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 MKLM6_RS19105 f8e14b914f43e044681587ddfb0babd0 628 ProSitePatterns PS00080 Multicopper oxidases signature 2. 610 621 - T 28-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 MKLM6_RS19105 f8e14b914f43e044681587ddfb0babd0 628 Gene3D G3DSA:2.60.40.420 37 188 9.4E-25 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS19105 f8e14b914f43e044681587ddfb0babd0 628 Gene3D G3DSA:2.60.40.420 399 628 5.3E-30 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS19105 f8e14b914f43e044681587ddfb0babd0 628 Gene3D G3DSA:2.60.40.420 189 398 1.6E-30 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS19105 f8e14b914f43e044681587ddfb0babd0 628 SUPERFAMILY SSF49503 544 627 1.22E-23 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS19105 f8e14b914f43e044681587ddfb0babd0 628 SUPERFAMILY SSF49503 383 448 1.22E-23 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS19105 f8e14b914f43e044681587ddfb0babd0 628 ProSitePatterns PS00079 Multicopper oxidases signature 1. 605 625 - T 28-03-2018 IPR033138 Multicopper oxidases, conserved site MKLM6_RS03375 e14c6c92bff97777dba20983df5e753c 300 SUPERFAMILY SSF53807 33 289 2.04E-50 T 28-03-2018 MKLM6_RS03375 e14c6c92bff97777dba20983df5e753c 300 Pfam PF01497 Periplasmic binding protein 36 263 8.7E-32 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 MKLM6_RS03375 e14c6c92bff97777dba20983df5e753c 300 Gene3D G3DSA:3.40.50.1980 32 139 1.8E-24 T 28-03-2018 MKLM6_RS03375 e14c6c92bff97777dba20983df5e753c 300 Gene3D G3DSA:3.40.50.1980 140 295 1.0E-25 T 28-03-2018 MKLM6_RS10680 67dc0756b1fa0c35e4cb07e1bb7578e1 304 PRINTS PR00990 Ribokinase signature 210 221 6.1E-9 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MKLM6_RS10680 67dc0756b1fa0c35e4cb07e1bb7578e1 304 PRINTS PR00990 Ribokinase signature 39 58 6.1E-9 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MKLM6_RS10680 67dc0756b1fa0c35e4cb07e1bb7578e1 304 PRINTS PR00990 Ribokinase signature 12 33 6.1E-9 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MKLM6_RS10680 67dc0756b1fa0c35e4cb07e1bb7578e1 304 Pfam PF00294 pfkB family carbohydrate kinase 9 283 2.0E-48 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB MKLM6_RS10680 67dc0756b1fa0c35e4cb07e1bb7578e1 304 SUPERFAMILY SSF53613 9 290 5.92E-64 T 28-03-2018 IPR029056 Ribokinase-like MKLM6_RS10680 67dc0756b1fa0c35e4cb07e1bb7578e1 304 Gene3D G3DSA:3.40.1190.20 8 300 1.0E-67 T 28-03-2018 IPR029056 Ribokinase-like MKLM6_RS10680 67dc0756b1fa0c35e4cb07e1bb7578e1 304 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 239 252 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MKLM6_RS14345 0222122e420b70e4296857ea2e9678e6 150 SUPERFAMILY SSF69500 1 143 8.89E-50 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain MKLM6_RS14345 0222122e420b70e4296857ea2e9678e6 150 Gene3D G3DSA:3.50.80.10 1 145 9.9E-47 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain MKLM6_RS14345 0222122e420b70e4296857ea2e9678e6 150 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 31.625 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 MKLM6_RS14345 0222122e420b70e4296857ea2e9678e6 150 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 144 2.5E-50 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 MKLM6_RS14345 0222122e420b70e4296857ea2e9678e6 150 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 4 143 3.0E-47 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 MKLM6_RS14660 5eb7026d4d760573456b5ca559f9c15f 236 Gene3D G3DSA:3.40.50.1360 2 236 2.0E-45 T 28-03-2018 MKLM6_RS14660 5eb7026d4d760573456b5ca559f9c15f 236 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 10 225 2.4E-46 T 28-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 MKLM6_RS14660 5eb7026d4d760573456b5ca559f9c15f 236 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 7 228 7.9E-47 T 28-03-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 MKLM6_RS14660 5eb7026d4d760573456b5ca559f9c15f 236 SUPERFAMILY SSF100950 3 228 1.56E-46 T 28-03-2018 MKLM6_RS15695 655071c1e833bd82b4205286b3f0ab12 132 SUPERFAMILY SSF55174 5 101 6.54E-29 T 28-03-2018 MKLM6_RS15695 655071c1e833bd82b4205286b3f0ab12 132 PIRSF PIRSF016821 4 132 5.3E-42 T 28-03-2018 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 MKLM6_RS15695 655071c1e833bd82b4205286b3f0ab12 132 Gene3D G3DSA:3.10.290.10 2 103 6.5E-26 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MKLM6_RS15695 655071c1e833bd82b4205286b3f0ab12 132 SMART SM00363 7 72 9.4E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MKLM6_RS15695 655071c1e833bd82b4205286b3f0ab12 132 Pfam PF01479 S4 domain 8 53 2.9E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MKLM6_RS10155 67169718ec70db77fb1a40d069e87209 400 SUPERFAMILY SSF58104 77 320 5.1E-42 T 28-03-2018 MKLM6_RS10155 67169718ec70db77fb1a40d069e87209 400 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 170 309 6.3E-28 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS10155 67169718ec70db77fb1a40d069e87209 400 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 223 252 5.2E-22 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MKLM6_RS10155 67169718ec70db77fb1a40d069e87209 400 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 272 301 5.2E-22 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MKLM6_RS10155 67169718ec70db77fb1a40d069e87209 400 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 194 221 5.2E-22 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MKLM6_RS10155 67169718ec70db77fb1a40d069e87209 400 SMART SM00283 93 354 2.3E-13 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS10155 67169718ec70db77fb1a40d069e87209 400 Gene3D G3DSA:1.10.287.950 67 137 0.28 T 28-03-2018 MKLM6_RS10155 67169718ec70db77fb1a40d069e87209 400 Gene3D G3DSA:1.10.287.950 138 391 1.1E-33 T 28-03-2018 MKLM6_RS12690 f977cce42c376563b2c56b998bcb2c08 452 Pfam PF00209 Sodium:neurotransmitter symporter family 10 127 4.8E-28 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MKLM6_RS12690 f977cce42c376563b2c56b998bcb2c08 452 Pfam PF00209 Sodium:neurotransmitter symporter family 158 447 1.7E-22 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MKLM6_RS12690 f977cce42c376563b2c56b998bcb2c08 452 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 33 47 - T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MKLM6_RS12690 f977cce42c376563b2c56b998bcb2c08 452 SUPERFAMILY SSF161070 10 449 7.98E-130 T 28-03-2018 MKLM6_RS12690 f977cce42c376563b2c56b998bcb2c08 452 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 17 38 3.1E-12 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MKLM6_RS12690 f977cce42c376563b2c56b998bcb2c08 452 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 306 325 3.1E-12 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MKLM6_RS12690 f977cce42c376563b2c56b998bcb2c08 452 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 46 65 3.1E-12 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MKLM6_RS16055 efa2ceb241a70ce8cedb407ed65c17b0 116 ProDom PD076485 YNEG CYTOPLASMIC ECS2130 STY1535 1 112 1.0E-36 T 28-03-2018 IPR020378 Protein of unknown function DUF4186 MKLM6_RS16055 efa2ceb241a70ce8cedb407ed65c17b0 116 Pfam PF13811 Domain of unknown function (DUF4186) 5 112 1.5E-49 T 28-03-2018 IPR020378 Protein of unknown function DUF4186 MKLM6_RS18135 f5919b439245bffc722dbf641235dad9 87 SMART SM00360 3 75 9.0E-19 T 28-03-2018 IPR000504 RNA recognition motif domain GO:0003676 MKLM6_RS18135 f5919b439245bffc722dbf641235dad9 87 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 4 72 2.2E-16 T 28-03-2018 IPR000504 RNA recognition motif domain GO:0003676 MKLM6_RS18135 f5919b439245bffc722dbf641235dad9 87 SUPERFAMILY SSF54928 2 80 4.57E-22 T 28-03-2018 IPR000504 RNA recognition motif domain GO:0003676 MKLM6_RS18135 f5919b439245bffc722dbf641235dad9 87 Gene3D G3DSA:3.30.70.330 1 87 5.7E-21 T 28-03-2018 MKLM6_RS15470 688e6f39d817edf290b6d55d064f079d 482 Gene3D G3DSA:1.20.1600.10 19 476 2.0E-67 T 28-03-2018 MKLM6_RS15470 688e6f39d817edf290b6d55d064f079d 482 Pfam PF02321 Outer membrane efflux protein 288 458 5.9E-13 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS15470 688e6f39d817edf290b6d55d064f079d 482 Pfam PF02321 Outer membrane efflux protein 69 259 1.2E-18 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS15470 688e6f39d817edf290b6d55d064f079d 482 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 11 471 2.9E-96 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 MKLM6_RS15470 688e6f39d817edf290b6d55d064f079d 482 SUPERFAMILY SSF56954 4 33 1.02E-74 T 28-03-2018 MKLM6_RS15470 688e6f39d817edf290b6d55d064f079d 482 SUPERFAMILY SSF56954 59 473 1.02E-74 T 28-03-2018 MKLM6_RS01100 97962c9ec37b899f724d55c9ac77eacb 395 Pfam PF04932 O-Antigen ligase 168 322 7.2E-6 T 28-03-2018 IPR007016 O-antigen ligase-related MKLM6_RS21645 09e5fb7bc4cb85fca72fd029d7eb0fbf 106 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 5 88 2.6E-33 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 MKLM6_RS21645 09e5fb7bc4cb85fca72fd029d7eb0fbf 106 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 6 91 1.6E-16 T 28-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 MKLM6_RS21645 09e5fb7bc4cb85fca72fd029d7eb0fbf 106 Gene3D G3DSA:1.10.287.1080 1 94 6.2E-27 T 28-03-2018 MKLM6_RS21645 09e5fb7bc4cb85fca72fd029d7eb0fbf 106 SUPERFAMILY SSF101386 4 94 6.73E-28 T 28-03-2018 MKLM6_RS21645 09e5fb7bc4cb85fca72fd029d7eb0fbf 106 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 2 88 21.227 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 MKLM6_RS13205 fd4bd9b29ce7685c6fdeb9df36d37c57 394 Gene3D G3DSA:1.10.1740.10 308 392 4.3E-33 T 28-03-2018 MKLM6_RS13205 fd4bd9b29ce7685c6fdeb9df36d37c57 394 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 133 5.1E-45 T 28-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 MKLM6_RS13205 fd4bd9b29ce7685c6fdeb9df36d37c57 394 Pfam PF13288 DXP reductoisomerase C-terminal domain 267 383 3.7E-45 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 MKLM6_RS13205 fd4bd9b29ce7685c6fdeb9df36d37c57 394 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 147 235 5.2E-38 T 28-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 MKLM6_RS13205 fd4bd9b29ce7685c6fdeb9df36d37c57 394 Gene3D G3DSA:3.40.50.720 1 151 3.0E-49 T 28-03-2018 MKLM6_RS13205 fd4bd9b29ce7685c6fdeb9df36d37c57 394 SUPERFAMILY SSF51735 2 151 1.35E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS13205 fd4bd9b29ce7685c6fdeb9df36d37c57 394 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 388 47.288 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 MKLM6_RS13205 fd4bd9b29ce7685c6fdeb9df36d37c57 394 SUPERFAMILY SSF69055 298 391 1.57E-33 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 MKLM6_RS13205 fd4bd9b29ce7685c6fdeb9df36d37c57 394 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 389 3.0E-158 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 MKLM6_RS13205 fd4bd9b29ce7685c6fdeb9df36d37c57 394 SUPERFAMILY SSF55347 127 270 2.32E-60 T 28-03-2018 MKLM6_RS13205 fd4bd9b29ce7685c6fdeb9df36d37c57 394 PIRSF PIRSF006205 1 394 3.0E-154 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 MKLM6_RS08060 43895c2d29f6e13b0bf39acb8cfb4466 618 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 336 358 1.6E-22 T 28-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 MKLM6_RS08060 43895c2d29f6e13b0bf39acb8cfb4466 618 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 131 150 1.6E-22 T 28-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 MKLM6_RS08060 43895c2d29f6e13b0bf39acb8cfb4466 618 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 97 109 1.6E-22 T 28-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 MKLM6_RS08060 43895c2d29f6e13b0bf39acb8cfb4466 618 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 359 373 1.6E-22 T 28-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 MKLM6_RS08060 43895c2d29f6e13b0bf39acb8cfb4466 618 Pfam PF01555 DNA methylase 97 391 8.9E-52 T 28-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 MKLM6_RS08060 43895c2d29f6e13b0bf39acb8cfb4466 618 SUPERFAMILY SSF53335 307 407 3.64E-75 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS08060 43895c2d29f6e13b0bf39acb8cfb4466 618 SUPERFAMILY SSF53335 73 244 3.64E-75 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS08060 43895c2d29f6e13b0bf39acb8cfb4466 618 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 100 106 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MKLM6_RS08060 43895c2d29f6e13b0bf39acb8cfb4466 618 PIRSF PIRSF015855 523 602 25.0 T 28-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 MKLM6_RS08060 43895c2d29f6e13b0bf39acb8cfb4466 618 PIRSF PIRSF015855 65 503 5.3E-119 T 28-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 MKLM6_RS08060 43895c2d29f6e13b0bf39acb8cfb4466 618 Gene3D G3DSA:3.40.50.150 74 416 1.6E-64 T 28-03-2018 MKLM6_RS20985 6aaf28f426cfb76a4613947e76ab7ee4 383 Pfam PF04773 FecR protein 180 272 5.1E-23 T 28-03-2018 IPR006860 FecR protein MKLM6_RS20985 6aaf28f426cfb76a4613947e76ab7ee4 383 Pfam PF16220 Domain of unknown function (DUF4880) 15 56 8.4E-14 T 28-03-2018 IPR032623 FecR, N-terminal MKLM6_RS20985 6aaf28f426cfb76a4613947e76ab7ee4 383 PIRSF PIRSF018266 4 383 2.5E-73 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component MKLM6_RS11985 31796b9cd17d150278133d2ec4ed31a5 476 Pfam PF09423 PhoD-like phosphatase 149 381 2.1E-29 T 28-03-2018 IPR018946 Alkaline phosphatase D-related MKLM6_RS11985 31796b9cd17d150278133d2ec4ed31a5 476 SUPERFAMILY SSF56300 147 396 2.39E-22 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS11985 31796b9cd17d150278133d2ec4ed31a5 476 Gene3D G3DSA:3.60.21.10 117 456 4.4E-32 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS10325 898cf284e42878ae53e4808079c29097 181 Gene3D G3DSA:2.40.50.180 40 98 4.9E-15 T 28-03-2018 MKLM6_RS10325 898cf284e42878ae53e4808079c29097 181 SUPERFAMILY SSF50341 17 162 2.75E-34 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS10325 898cf284e42878ae53e4808079c29097 181 Gene3D G3DSA:2.30.30.40 99 152 1.0E-16 T 28-03-2018 MKLM6_RS10325 898cf284e42878ae53e4808079c29097 181 Pfam PF01584 CheW-like domain 21 160 1.1E-31 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS10325 898cf284e42878ae53e4808079c29097 181 SMART SM00260 17 158 5.0E-26 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS09220 eb784c2a1b06859dc85c3e3168d7d177 155 PIRSF PIRSF000239 1 155 1.2E-28 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MKLM6_RS09220 eb784c2a1b06859dc85c3e3168d7d177 155 Gene3D G3DSA:3.40.30.10 1 155 2.6E-38 T 28-03-2018 MKLM6_RS09220 eb784c2a1b06859dc85c3e3168d7d177 155 Pfam PF00578 AhpC/TSA family 6 133 3.1E-36 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MKLM6_RS09220 eb784c2a1b06859dc85c3e3168d7d177 155 SUPERFAMILY SSF52833 4 155 1.58E-51 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS16895 89cb3b951deb4ff545ef4523ccd8dd06 232 SUPERFAMILY SSF56214 8 100 1.06E-19 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 MKLM6_RS16895 89cb3b951deb4ff545ef4523ccd8dd06 232 Gene3D G3DSA:3.90.470.20 7 118 6.4E-22 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 MKLM6_RS16895 89cb3b951deb4ff545ef4523ccd8dd06 232 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 109 205 4.5E-13 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 MKLM6_RS16895 89cb3b951deb4ff545ef4523ccd8dd06 232 SUPERFAMILY SSF56214 109 218 3.27E-20 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 MKLM6_RS16895 89cb3b951deb4ff545ef4523ccd8dd06 232 Gene3D G3DSA:3.90.470.20 119 219 5.8E-14 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 MKLM6_RS04680 1df2270fe0fe1884e21e55bae2e19c1d 92 Gene3D G3DSA:3.10.20.30 7 92 2.5E-8 T 28-03-2018 IPR012675 Beta-grasp domain MKLM6_RS04680 1df2270fe0fe1884e21e55bae2e19c1d 92 SUPERFAMILY SSF54285 16 92 2.43E-10 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MKLM6_RS19890 bf94ded4202312abc8c216bf844e30f3 452 Gene3D G3DSA:3.10.580.10 129 266 4.9E-20 T 28-03-2018 MKLM6_RS19890 bf94ded4202312abc8c216bf844e30f3 452 Pfam PF03448 MgtE intracellular N domain 37 136 4.7E-17 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain MKLM6_RS19890 bf94ded4202312abc8c216bf844e30f3 452 Gene3D G3DSA:1.25.60.10 3 128 3.4E-15 T 28-03-2018 MKLM6_RS19890 bf94ded4202312abc8c216bf844e30f3 452 SMART SM00924 36 139 1.6E-24 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain MKLM6_RS19890 bf94ded4202312abc8c216bf844e30f3 452 Gene3D G3DSA:1.10.357.20 279 452 5.6E-34 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 MKLM6_RS19890 bf94ded4202312abc8c216bf844e30f3 452 SUPERFAMILY SSF161093 280 451 1.96E-49 T 28-03-2018 MKLM6_RS19890 bf94ded4202312abc8c216bf844e30f3 452 TIGRFAM TIGR00400 mgtE: magnesium transporter 11 451 9.2E-81 T 28-03-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 MKLM6_RS19890 bf94ded4202312abc8c216bf844e30f3 452 SUPERFAMILY SSF54631 138 277 1.23E-25 T 28-03-2018 MKLM6_RS19890 bf94ded4202312abc8c216bf844e30f3 452 Pfam PF01769 Divalent cation transporter 323 444 3.9E-25 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 MKLM6_RS19890 bf94ded4202312abc8c216bf844e30f3 452 Pfam PF00571 CBS domain 203 257 4.8E-4 T 28-03-2018 IPR000644 CBS domain MKLM6_RS19890 bf94ded4202312abc8c216bf844e30f3 452 Pfam PF00571 CBS domain 140 197 0.0044 T 28-03-2018 IPR000644 CBS domain MKLM6_RS19890 bf94ded4202312abc8c216bf844e30f3 452 SUPERFAMILY SSF158791 13 136 5.1E-23 T 28-03-2018 MKLM6_RS04835 b5ce5bcb741c97d78a4c741c4b2c2611 835 Gene3D G3DSA:1.25.40.10 620 832 3.8E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS04835 b5ce5bcb741c97d78a4c741c4b2c2611 835 Pfam PF01973 Protein of unknown function DUF115 181 344 4.0E-41 T 28-03-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like MKLM6_RS04835 b5ce5bcb741c97d78a4c741c4b2c2611 835 Gene3D G3DSA:3.90.1480.10 184 520 2.3E-35 T 28-03-2018 MKLM6_RS15130 d98ecc3f5ff2c639803c7ad8c10f040c 247 SMART SM00900 144 236 1.9E-31 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 MKLM6_RS15130 d98ecc3f5ff2c639803c7ad8c10f040c 247 TIGRFAM TIGR01947 rnfG: electron transport complex, RnfABCDGE type, G subunit 54 237 4.8E-57 T 28-03-2018 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 MKLM6_RS15130 d98ecc3f5ff2c639803c7ad8c10f040c 247 PIRSF PIRSF006091 41 247 5.0E-66 T 28-03-2018 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 MKLM6_RS15130 d98ecc3f5ff2c639803c7ad8c10f040c 247 Pfam PF04205 FMN-binding domain 144 233 9.6E-17 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 MKLM6_RS15130 d98ecc3f5ff2c639803c7ad8c10f040c 247 Hamap MF_00479 Electron transport complex subunit RsxG [rsxG]. 45 238 23.385 T 28-03-2018 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 MKLM6_RS08185 e7692c2e465de3ffa2047efde23714c4 487 SUPERFAMILY SSF53649 289 474 9.81E-20 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MKLM6_RS08185 e7692c2e465de3ffa2047efde23714c4 487 Pfam PF07394 Protein of unknown function (DUF1501) 62 486 2.3E-132 T 28-03-2018 IPR010869 Protein of unknown function DUF1501 MKLM6_RS08185 e7692c2e465de3ffa2047efde23714c4 487 Gene3D G3DSA:3.40.720.10 58 476 3.2E-19 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MKLM6_RS01485 9e0d5f477c86c708775621522c3ea685 296 Pfam PF01040 UbiA prenyltransferase family 26 271 1.9E-64 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 MKLM6_RS01485 9e0d5f477c86c708775621522c3ea685 296 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 9 290 20.499 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 MKLM6_RS01485 9e0d5f477c86c708775621522c3ea685 296 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 11 289 5.4E-101 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 MKLM6_RS13610 c4bff7db515ef92a9c8d0cfd7bcd510b 390 Gene3D G3DSA:3.40.640.10 48 278 1.1E-74 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS13610 c4bff7db515ef92a9c8d0cfd7bcd510b 390 SUPERFAMILY SSF53383 4 386 2.06E-128 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS13610 c4bff7db515ef92a9c8d0cfd7bcd510b 390 PIRSF PIRSF000521 2 152 3.7E-14 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MKLM6_RS13610 c4bff7db515ef92a9c8d0cfd7bcd510b 390 PIRSF PIRSF000521 160 388 1.5E-36 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MKLM6_RS13610 c4bff7db515ef92a9c8d0cfd7bcd510b 390 Pfam PF00202 Aminotransferase class-III 14 383 5.5E-118 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MKLM6_RS13610 c4bff7db515ef92a9c8d0cfd7bcd510b 390 Gene3D G3DSA:3.90.1150.10 279 390 1.7E-32 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS13610 c4bff7db515ef92a9c8d0cfd7bcd510b 390 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 5 385 3.6E-151 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 MKLM6_RS13610 c4bff7db515ef92a9c8d0cfd7bcd510b 390 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 2 386 45.509 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 MKLM6_RS22250 67714d148a33845589f2315429d312b1 102 Pfam PF14412 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH 11 50 5.6E-6 T 28-03-2018 IPR032871 AHH domain-containing protein MKLM6_RS18925 61868baf92db85ed5662105bf230624a 327 Pfam PF02685 Glucokinase 3 325 3.1E-97 T 28-03-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 MKLM6_RS18925 61868baf92db85ed5662105bf230624a 327 TIGRFAM TIGR00749 glk: glucokinase 3 320 1.7E-72 T 28-03-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 MKLM6_RS18925 61868baf92db85ed5662105bf230624a 327 Gene3D G3DSA:3.40.367.20 109 310 2.3E-29 T 28-03-2018 MKLM6_RS18925 61868baf92db85ed5662105bf230624a 327 SUPERFAMILY SSF53067 1 324 1.46E-49 T 28-03-2018 MKLM6_RS18925 61868baf92db85ed5662105bf230624a 327 Hamap MF_00524 Glucokinase [glk]. 1 327 32.407 T 28-03-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 MKLM6_RS18925 61868baf92db85ed5662105bf230624a 327 Gene3D G3DSA:3.30.420.40 1 108 3.6E-18 T 28-03-2018 MKLM6_RS15005 155e213d0f6b5aa4f736dea8d4028253 112 Gene3D G3DSA:2.20.25.10 2 40 2.4E-16 T 28-03-2018 MKLM6_RS15005 155e213d0f6b5aa4f736dea8d4028253 112 Pfam PF03831 PhnA domain 45 112 6.5E-34 T 28-03-2018 IPR013988 PhnA protein, C-terminal MKLM6_RS15005 155e213d0f6b5aa4f736dea8d4028253 112 SUPERFAMILY SSF82057 40 112 2.93E-29 T 28-03-2018 MKLM6_RS15005 155e213d0f6b5aa4f736dea8d4028253 112 Pfam PF08274 PhnA Zinc-Ribbon 3 32 7.5E-15 T 28-03-2018 IPR013987 PhnA protein, N-terminal MKLM6_RS15005 155e213d0f6b5aa4f736dea8d4028253 112 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 3 112 1.6E-50 T 28-03-2018 IPR004624 PhnA protein MKLM6_RS15005 155e213d0f6b5aa4f736dea8d4028253 112 Gene3D G3DSA:2.30.30.40 44 111 6.0E-37 T 28-03-2018 MKLM6_RS15005 155e213d0f6b5aa4f736dea8d4028253 112 SUPERFAMILY SSF57783 3 37 3.4E-13 T 28-03-2018 MKLM6_RS12495 d71a075e7ec21fa364ec9001672b6421 308 SUPERFAMILY SSF55073 150 306 2.2E-43 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS12495 d71a075e7ec21fa364ec9001672b6421 308 SMART SM00448 1 114 1.3E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS12495 d71a075e7ec21fa364ec9001672b6421 308 Pfam PF00072 Response regulator receiver domain 3 112 1.9E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS12495 d71a075e7ec21fa364ec9001672b6421 308 Pfam PF00990 Diguanylate cyclase, GGDEF domain 146 304 3.1E-45 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS12495 d71a075e7ec21fa364ec9001672b6421 308 Gene3D G3DSA:3.40.50.2300 1 146 1.2E-32 T 28-03-2018 MKLM6_RS12495 d71a075e7ec21fa364ec9001672b6421 308 SUPERFAMILY SSF52172 1 140 4.41E-35 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS12495 d71a075e7ec21fa364ec9001672b6421 308 Gene3D G3DSA:3.30.70.270 147 308 2.8E-48 T 28-03-2018 MKLM6_RS12495 d71a075e7ec21fa364ec9001672b6421 308 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 141 307 1.6E-48 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS12495 d71a075e7ec21fa364ec9001672b6421 308 SMART SM00267 134 308 7.9E-60 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS12595 5c53dd377386f9a96079d178bc2781b7 365 Gene3D G3DSA:3.40.430.10 127 363 2.7E-72 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 MKLM6_RS12595 5c53dd377386f9a96079d178bc2781b7 365 Pfam PF01872 RibD C-terminal domain 149 354 1.7E-51 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MKLM6_RS12595 5c53dd377386f9a96079d178bc2781b7 365 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 148 359 2.5E-63 T 28-03-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 MKLM6_RS12595 5c53dd377386f9a96079d178bc2781b7 365 SUPERFAMILY SSF53927 6 146 3.01E-46 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 MKLM6_RS12595 5c53dd377386f9a96079d178bc2781b7 365 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 4 101 3.9E-19 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain MKLM6_RS12595 5c53dd377386f9a96079d178bc2781b7 365 SUPERFAMILY SSF53597 147 358 6.94E-60 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 MKLM6_RS12595 5c53dd377386f9a96079d178bc2781b7 365 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 10 355 4.1E-122 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 MKLM6_RS12595 5c53dd377386f9a96079d178bc2781b7 365 PIRSF PIRSF006769 1 362 5.2E-127 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 MKLM6_RS12595 5c53dd377386f9a96079d178bc2781b7 365 Gene3D G3DSA:3.40.140.10 1 126 9.3E-34 T 28-03-2018 MKLM6_RS06395 fc8d1284e323221453d891de18ff968d 620 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 13 618 1.4E-270 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MKLM6_RS06395 fc8d1284e323221453d891de18ff968d 620 Gene3D G3DSA:3.40.50.970 1 295 1.5E-82 T 28-03-2018 MKLM6_RS06395 fc8d1284e323221453d891de18ff968d 620 Gene3D G3DSA:3.40.50.970 296 485 2.2E-61 T 28-03-2018 MKLM6_RS06395 fc8d1284e323221453d891de18ff968d 620 Pfam PF02779 Transketolase, pyrimidine binding domain 320 479 3.3E-36 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MKLM6_RS06395 fc8d1284e323221453d891de18ff968d 620 ProSitePatterns PS00802 Transketolase signature 2. 425 441 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MKLM6_RS06395 fc8d1284e323221453d891de18ff968d 620 SUPERFAMILY SSF52922 491 618 9.55E-33 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MKLM6_RS06395 fc8d1284e323221453d891de18ff968d 620 SUPERFAMILY SSF52518 318 503 9.7E-57 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS06395 fc8d1284e323221453d891de18ff968d 620 ProSitePatterns PS00801 Transketolase signature 1. 35 54 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MKLM6_RS06395 fc8d1284e323221453d891de18ff968d 620 Pfam PF02780 Transketolase, C-terminal domain 495 611 1.7E-27 T 28-03-2018 IPR033248 Transketolase, C-terminal domain MKLM6_RS06395 fc8d1284e323221453d891de18ff968d 620 SMART SM00861 319 483 2.3E-64 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MKLM6_RS06395 fc8d1284e323221453d891de18ff968d 620 Gene3D G3DSA:3.40.50.920 495 620 1.0E-35 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MKLM6_RS06395 fc8d1284e323221453d891de18ff968d 620 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 10 281 2.6E-124 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MKLM6_RS06395 fc8d1284e323221453d891de18ff968d 620 SUPERFAMILY SSF52518 8 198 2.85E-78 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS06395 fc8d1284e323221453d891de18ff968d 620 SUPERFAMILY SSF52518 242 381 2.85E-78 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS06395 fc8d1284e323221453d891de18ff968d 620 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 9 620 46.154 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MKLM6_RS10885 0e0e34312c8be8d74c4411f76bc8881c 144 Pfam PF03100 CcmE 5 131 6.1E-45 T 28-03-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 MKLM6_RS10885 0e0e34312c8be8d74c4411f76bc8881c 144 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 2 141 31.594 T 28-03-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 MKLM6_RS10885 0e0e34312c8be8d74c4411f76bc8881c 144 SUPERFAMILY SSF82093 30 136 7.59E-39 T 28-03-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 MKLM6_RS10885 0e0e34312c8be8d74c4411f76bc8881c 144 Gene3D G3DSA:2.40.50.140 27 125 1.6E-32 T 28-03-2018 MKLM6_RS17140 05c5959ad3d8bc7732d380d0b6d9ec69 587 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS17140 05c5959ad3d8bc7732d380d0b6d9ec69 587 SUPERFAMILY SSF52540 338 560 4.8E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS17140 05c5959ad3d8bc7732d380d0b6d9ec69 587 SMART SM00382 35 218 1.2E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS17140 05c5959ad3d8bc7732d380d0b6d9ec69 587 SMART SM00382 364 554 6.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS17140 05c5959ad3d8bc7732d380d0b6d9ec69 587 SUPERFAMILY SSF52540 10 227 1.36E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS17140 05c5959ad3d8bc7732d380d0b6d9ec69 587 Pfam PF00005 ABC transporter 26 169 7.9E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS17140 05c5959ad3d8bc7732d380d0b6d9ec69 587 Pfam PF00005 ABC transporter 356 499 1.1E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS17140 05c5959ad3d8bc7732d380d0b6d9ec69 587 Gene3D G3DSA:3.40.50.300 8 260 1.4E-54 T 28-03-2018 MKLM6_RS17140 05c5959ad3d8bc7732d380d0b6d9ec69 587 Gene3D G3DSA:3.40.50.300 336 573 4.4E-64 T 28-03-2018 MKLM6_RS05510 4b4d2e86a95b830dbd6ee445f4d4c47c 210 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 42 49 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MKLM6_RS05510 4b4d2e86a95b830dbd6ee445f4d4c47c 210 SMART SM00947 30 194 8.7E-62 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MKLM6_RS05510 4b4d2e86a95b830dbd6ee445f4d4c47c 210 Pfam PF00484 Carbonic anhydrase 38 189 1.7E-48 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MKLM6_RS05510 4b4d2e86a95b830dbd6ee445f4d4c47c 210 SUPERFAMILY SSF53056 2 193 1.05E-65 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MKLM6_RS05510 4b4d2e86a95b830dbd6ee445f4d4c47c 210 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 82 102 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MKLM6_RS05510 4b4d2e86a95b830dbd6ee445f4d4c47c 210 Gene3D G3DSA:3.40.1050.10 1 207 7.7E-67 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MKLM6_RS21085 4b2f53910bf5a7439a371d050c9d4f89 154 Pfam PF06271 RDD family 20 144 9.2E-25 T 28-03-2018 IPR010432 RDD MKLM6_RS10930 50de9c695cf688cff69527fb7a85ed56 690 Pfam PF02554 Carbon starvation protein CstA 36 410 2.7E-163 T 28-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 MKLM6_RS10930 50de9c695cf688cff69527fb7a85ed56 690 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 467 591 2.8E-33 T 28-03-2018 IPR025299 CstA, C-terminal domain MKLM6_RS20280 c0bfff3732d3fe54b1c0dbe50654e6e7 268 Pfam PF07024 ImpE protein 139 260 7.4E-46 T 28-03-2018 IPR009211 Predicted virulence protein, SciE type MKLM6_RS20280 c0bfff3732d3fe54b1c0dbe50654e6e7 268 Gene3D G3DSA:1.25.40.10 2 253 1.5E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS20280 c0bfff3732d3fe54b1c0dbe50654e6e7 268 PIRSF PIRSF029288 1 266 6.9E-92 T 28-03-2018 IPR009211 Predicted virulence protein, SciE type MKLM6_RS20280 c0bfff3732d3fe54b1c0dbe50654e6e7 268 SUPERFAMILY SSF144059 3 261 6.67E-89 T 28-03-2018 MKLM6_RS22515 917bc12d1ab347e3869b84bc6fcc7690 932 Pfam PF06986 Type-1V conjugative transfer system mating pair stabilisation 763 838 2.8E-25 T 28-03-2018 IPR014121 Type-F conjugative transfer system mating-pair stabilisation protein TraN MKLM6_RS22515 917bc12d1ab347e3869b84bc6fcc7690 932 Pfam PF06986 Type-1V conjugative transfer system mating pair stabilisation 422 600 1.2E-16 T 28-03-2018 IPR014121 Type-F conjugative transfer system mating-pair stabilisation protein TraN MKLM6_RS01335 20630941adacd923d2941902069c2d78 334 Pfam PF00268 Ribonucleotide reductase, small chain 19 298 4.3E-58 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MKLM6_RS01335 20630941adacd923d2941902069c2d78 334 SUPERFAMILY SSF47240 3 327 2.43E-79 T 28-03-2018 IPR009078 Ferritin-like superfamily MKLM6_RS01335 20630941adacd923d2941902069c2d78 334 PIRSF PIRSF000355 3 334 1.8E-111 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MKLM6_RS01335 20630941adacd923d2941902069c2d78 334 Gene3D G3DSA:1.10.620.20 2 315 9.1E-80 T 28-03-2018 MKLM6_RS20070 fd83a099dc199d1cc1ddb27a1a122c5e 258 Pfam PF11860 N-acetylmuramidase 27 190 2.9E-56 T 28-03-2018 IPR024408 N-acetylmuramidase MKLM6_RS20070 fd83a099dc199d1cc1ddb27a1a122c5e 258 Pfam PF01471 Putative peptidoglycan binding domain 198 246 2.3E-12 T 28-03-2018 IPR002477 Peptidoglycan binding-like MKLM6_RS20070 fd83a099dc199d1cc1ddb27a1a122c5e 258 SUPERFAMILY SSF47090 195 250 2.67E-12 T 28-03-2018 IPR002477 Peptidoglycan binding-like MKLM6_RS20070 fd83a099dc199d1cc1ddb27a1a122c5e 258 Gene3D G3DSA:1.10.530.10 12 195 2.9E-6 T 28-03-2018 MKLM6_RS20070 fd83a099dc199d1cc1ddb27a1a122c5e 258 Gene3D G3DSA:1.10.101.10 196 254 2.1E-12 T 28-03-2018 IPR002477 Peptidoglycan binding-like MKLM6_RS04510 4c3b6d11ac8dbd25a02eb7e95ef6fef3 231 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 9 229 9.7E-70 T 28-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MKLM6_RS04510 4c3b6d11ac8dbd25a02eb7e95ef6fef3 231 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 6 227 43.207 T 28-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MKLM6_RS04510 4c3b6d11ac8dbd25a02eb7e95ef6fef3 231 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 105 112 - T 28-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MKLM6_RS04510 4c3b6d11ac8dbd25a02eb7e95ef6fef3 231 Gene3D G3DSA:3.90.550.10 1 231 3.2E-49 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS04510 4c3b6d11ac8dbd25a02eb7e95ef6fef3 231 SUPERFAMILY SSF53448 7 228 8.02E-60 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS04510 4c3b6d11ac8dbd25a02eb7e95ef6fef3 231 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 8 227 6.8E-69 T 28-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MKLM6_RS11940 283b2a265296a514ce6557997c848ce8 852 Pfam PF00330 Aconitase family (aconitate hydratase) 465 810 4.0E-39 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MKLM6_RS11940 283b2a265296a514ce6557997c848ce8 852 Pfam PF06434 Aconitate hydratase 2 N-terminus 168 375 7.7E-100 T 28-03-2018 IPR015929 Aconitase B, swivel GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MKLM6_RS11940 283b2a265296a514ce6557997c848ce8 852 SUPERFAMILY SSF52016 161 364 4.71E-69 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MKLM6_RS11940 283b2a265296a514ce6557997c848ce8 852 TIGRFAM TIGR00117 acnB: aconitate hydratase 2 1 846 0.0 T 28-03-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MKLM6_RS11940 283b2a265296a514ce6557997c848ce8 852 SUPERFAMILY SSF53732 372 848 1.96E-148 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MKLM6_RS11940 283b2a265296a514ce6557997c848ce8 852 ProSitePatterns PS00450 Aconitase family signature 1. 695 712 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MKLM6_RS11940 283b2a265296a514ce6557997c848ce8 852 SUPERFAMILY SSF74778 1 159 5.62E-68 T 28-03-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MKLM6_RS11940 283b2a265296a514ce6557997c848ce8 852 Gene3D G3DSA:3.30.499.10 676 852 1.1E-51 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 MKLM6_RS11940 283b2a265296a514ce6557997c848ce8 852 Gene3D G3DSA:3.40.1060.10 514 675 2.2E-26 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 MKLM6_RS11940 283b2a265296a514ce6557997c848ce8 852 ProSitePatterns PS01244 Aconitase family signature 2. 753 766 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MKLM6_RS11940 283b2a265296a514ce6557997c848ce8 852 PIRSF PIRSF036687 1 851 0.0 T 28-03-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MKLM6_RS11940 283b2a265296a514ce6557997c848ce8 852 Gene3D G3DSA:3.20.19.10 162 356 1.0E-34 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MKLM6_RS11940 283b2a265296a514ce6557997c848ce8 852 Gene3D G3DSA:3.30.499.10 395 513 1.7E-10 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 MKLM6_RS11940 283b2a265296a514ce6557997c848ce8 852 Pfam PF11791 Aconitate B N-terminal domain 4 156 5.3E-66 T 28-03-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MKLM6_RS02670 35c2261205edd4864d351f9aca6a7e6c 170 Pfam PF02834 LigT like Phosphoesterase 21 82 1.0E-6 T 28-03-2018 IPR014051 Phosphoesterase, HXTX MKLM6_RS02670 35c2261205edd4864d351f9aca6a7e6c 170 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 2 167 15.291 T 28-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 MKLM6_RS02670 35c2261205edd4864d351f9aca6a7e6c 170 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 3 165 5.9E-25 T 28-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 MKLM6_RS02670 35c2261205edd4864d351f9aca6a7e6c 170 SUPERFAMILY SSF55144 2 166 2.62E-28 T 28-03-2018 IPR009097 Cyclic phosphodiesterase MKLM6_RS02670 35c2261205edd4864d351f9aca6a7e6c 170 Gene3D G3DSA:3.90.1140.10 1 166 2.3E-25 T 28-03-2018 MKLM6_RS10150 83633b35f0f5b44bbec49093facd9b84 352 SMART SM00448 4 119 2.6E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS10150 83633b35f0f5b44bbec49093facd9b84 352 SUPERFAMILY SSF52172 3 108 1.17E-26 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS10150 83633b35f0f5b44bbec49093facd9b84 352 Gene3D G3DSA:3.40.50.180 164 352 5.9E-71 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MKLM6_RS10150 83633b35f0f5b44bbec49093facd9b84 352 Pfam PF00072 Response regulator receiver domain 7 109 1.9E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS10150 83633b35f0f5b44bbec49093facd9b84 352 Pfam PF01339 CheB methylesterase 169 347 1.2E-55 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MKLM6_RS10150 83633b35f0f5b44bbec49093facd9b84 352 SUPERFAMILY SSF52738 164 348 1.96E-66 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MKLM6_RS10150 83633b35f0f5b44bbec49093facd9b84 352 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 4 352 38.827 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MKLM6_RS10150 83633b35f0f5b44bbec49093facd9b84 352 PIRSF PIRSF000876 1 352 1.2E-129 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MKLM6_RS10150 83633b35f0f5b44bbec49093facd9b84 352 Gene3D G3DSA:3.40.50.2300 1 163 1.4E-27 T 28-03-2018 MKLM6_RS00540 ddbb26b3d442d2cd2159f3fff39261ab 334 Pfam PF13185 GAF domain 23 155 8.5E-15 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS00540 ddbb26b3d442d2cd2159f3fff39261ab 334 SUPERFAMILY SSF55781 18 159 3.93E-23 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS00540 ddbb26b3d442d2cd2159f3fff39261ab 334 Pfam PF00990 Diguanylate cyclase, GGDEF domain 171 324 1.2E-39 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS00540 ddbb26b3d442d2cd2159f3fff39261ab 334 Gene3D G3DSA:3.30.70.270 187 328 2.6E-47 T 28-03-2018 MKLM6_RS00540 ddbb26b3d442d2cd2159f3fff39261ab 334 Gene3D G3DSA:3.30.450.40 6 186 6.3E-25 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS00540 ddbb26b3d442d2cd2159f3fff39261ab 334 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 170 324 2.6E-37 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS00540 ddbb26b3d442d2cd2159f3fff39261ab 334 SMART SM00267 160 330 1.8E-39 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS00540 ddbb26b3d442d2cd2159f3fff39261ab 334 SUPERFAMILY SSF55073 176 325 9.42E-40 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS00540 ddbb26b3d442d2cd2159f3fff39261ab 334 SMART SM00065 19 166 5.5E-7 T 28-03-2018 IPR003018 GAF domain GO:0005515 MKLM6_RS14670 433fcd8f9802ee6fad6af7f4f9857e22 481 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 168 1.2E-51 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 MKLM6_RS14670 433fcd8f9802ee6fad6af7f4f9857e22 481 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 252 264 - T 28-03-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MKLM6_RS14670 433fcd8f9802ee6fad6af7f4f9857e22 481 Gene3D G3DSA:3.40.50.720 1 179 3.3E-34 T 28-03-2018 MKLM6_RS14670 433fcd8f9802ee6fad6af7f4f9857e22 481 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 178 467 1.6E-130 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MKLM6_RS14670 433fcd8f9802ee6fad6af7f4f9857e22 481 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 4 468 6.9E-233 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MKLM6_RS14670 433fcd8f9802ee6fad6af7f4f9857e22 481 SUPERFAMILY SSF48179 176 471 7.78E-127 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MKLM6_RS14670 433fcd8f9802ee6fad6af7f4f9857e22 481 SMART SM01350 178 468 3.9E-215 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MKLM6_RS14670 433fcd8f9802ee6fad6af7f4f9857e22 481 Gene3D G3DSA:1.10.1040.10 180 433 3.5E-114 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MKLM6_RS14670 433fcd8f9802ee6fad6af7f4f9857e22 481 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 66 95 1.7E-84 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MKLM6_RS14670 433fcd8f9802ee6fad6af7f4f9857e22 481 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 167 195 1.7E-84 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MKLM6_RS14670 433fcd8f9802ee6fad6af7f4f9857e22 481 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 355 377 1.7E-84 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MKLM6_RS14670 433fcd8f9802ee6fad6af7f4f9857e22 481 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 248 275 1.7E-84 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MKLM6_RS14670 433fcd8f9802ee6fad6af7f4f9857e22 481 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 3 26 1.7E-84 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MKLM6_RS14670 433fcd8f9802ee6fad6af7f4f9857e22 481 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 119 144 1.7E-84 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MKLM6_RS14670 433fcd8f9802ee6fad6af7f4f9857e22 481 PIRSF PIRSF000109 1 476 1.1E-239 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MKLM6_RS14670 433fcd8f9802ee6fad6af7f4f9857e22 481 Gene3D G3DSA:1.20.5.320 434 481 2.1E-22 T 28-03-2018 MKLM6_RS14670 433fcd8f9802ee6fad6af7f4f9857e22 481 SUPERFAMILY SSF51735 3 176 2.63E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS12255 8d3ccf01780ad45373b9f3a4c4ad9440 413 Pfam PF02687 FtsX-like permease family 307 404 4.8E-10 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MKLM6_RS12255 8d3ccf01780ad45373b9f3a4c4ad9440 413 Pfam PF12704 MacB-like periplasmic core domain 23 242 2.8E-8 T 28-03-2018 IPR025857 MacB-like periplasmic core domain MKLM6_RS10390 8b63c0791ab260883a2d36af69160096 595 Gene3D G3DSA:2.60.120.200 137 334 7.2E-23 T 28-03-2018 MKLM6_RS10390 8b63c0791ab260883a2d36af69160096 595 Pfam PF10102 Domain of unknown function (DUF2341) 70 137 5.1E-16 T 28-03-2018 IPR018765 Domain of unknown function DUF2341 MKLM6_RS10390 8b63c0791ab260883a2d36af69160096 595 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 183 316 1.6E-14 T 28-03-2018 MKLM6_RS10390 8b63c0791ab260883a2d36af69160096 595 SUPERFAMILY SSF49899 143 320 7.36E-21 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain MKLM6_RS10390 8b63c0791ab260883a2d36af69160096 595 Pfam PF01618 MotA/TolQ/ExbB proton channel family 448 579 6.0E-27 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 MKLM6_RS11280 84f7c98cc59b39ed5e6ade9a6f6bd216 315 SUPERFAMILY SSF53448 2 225 3.7E-57 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS11280 84f7c98cc59b39ed5e6ade9a6f6bd216 315 Pfam PF00535 Glycosyl transferase family 2 4 120 5.3E-30 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MKLM6_RS11280 84f7c98cc59b39ed5e6ade9a6f6bd216 315 Gene3D G3DSA:3.90.550.10 1 297 3.1E-45 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS20375 966b5b738265dd1f60443760c09ee1b8 306 Gene3D G3DSA:1.10.443.10 114 288 8.2E-44 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS20375 966b5b738265dd1f60443760c09ee1b8 306 Pfam PF00589 Phage integrase family 113 280 6.0E-47 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS20375 966b5b738265dd1f60443760c09ee1b8 306 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 11 296 1.5E-107 T 28-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 MKLM6_RS20375 966b5b738265dd1f60443760c09ee1b8 306 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 7 294 56.989 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD MKLM6_RS20375 966b5b738265dd1f60443760c09ee1b8 306 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 10 90 1.7E-20 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MKLM6_RS20375 966b5b738265dd1f60443760c09ee1b8 306 Gene3D G3DSA:1.10.150.130 5 113 2.0E-27 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal MKLM6_RS20375 966b5b738265dd1f60443760c09ee1b8 306 SUPERFAMILY SSF56349 7 286 7.95E-59 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS07985 36187ef4579413242445ee756e577995 173 SUPERFAMILY SSF47175 61 164 1.62E-11 T 28-03-2018 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 MKLM6_RS07985 36187ef4579413242445ee756e577995 173 Gene3D G3DSA:1.20.120.10 52 165 3.1E-12 T 28-03-2018 MKLM6_RS07985 36187ef4579413242445ee756e577995 173 Pfam PF01322 Cytochrome C' 113 164 8.1E-8 T 28-03-2018 IPR002321 Cytochrome c, class II GO:0005506|GO:0009055|GO:0020037 MKLM6_RS06480 d42c835a2fd88c9c54e776bb37e7461e 482 SUPERFAMILY SSF56954 7 473 8.11E-108 T 28-03-2018 MKLM6_RS06480 d42c835a2fd88c9c54e776bb37e7461e 482 Gene3D G3DSA:1.20.1600.10 23 476 4.9E-96 T 28-03-2018 MKLM6_RS06480 d42c835a2fd88c9c54e776bb37e7461e 482 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 15 470 5.9E-113 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 MKLM6_RS06480 d42c835a2fd88c9c54e776bb37e7461e 482 Pfam PF02321 Outer membrane efflux protein 287 468 8.3E-26 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS06480 d42c835a2fd88c9c54e776bb37e7461e 482 Pfam PF02321 Outer membrane efflux protein 67 258 1.7E-30 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS16115 d08470421c37f16e6d20fdb7a4d3874a 167 Gene3D G3DSA:3.40.50.1820 2 165 6.2E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS16115 d08470421c37f16e6d20fdb7a4d3874a 167 SUPERFAMILY SSF53474 4 163 2.04E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS05015 79ca8d651c869d535035df3e8273c34a 263 Pfam PF02698 DUF218 domain 81 228 2.7E-23 T 28-03-2018 IPR003848 Domain of unknown function DUF218 MKLM6_RS05015 79ca8d651c869d535035df3e8273c34a 263 Gene3D G3DSA:3.40.50.620 70 216 9.1E-29 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS06540 0b1ea2782b737025c477023d8bdcbd32 345 SUPERFAMILY SSF56042 172 315 6.73E-20 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MKLM6_RS06540 0b1ea2782b737025c477023d8bdcbd32 345 Gene3D G3DSA:3.90.650.10 158 318 7.6E-16 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MKLM6_RS06540 0b1ea2782b737025c477023d8bdcbd32 345 Gene3D G3DSA:3.30.1330.10 27 157 1.6E-20 T 28-03-2018 IPR016188 PurM-like, N-terminal domain MKLM6_RS06540 0b1ea2782b737025c477023d8bdcbd32 345 Pfam PF02769 AIR synthase related protein, C-terminal domain 201 298 1.5E-9 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MKLM6_RS06540 0b1ea2782b737025c477023d8bdcbd32 345 TIGRFAM TIGR04049 AIR_rel_sll0787: AIR synthase-related protein, sll0787 family 34 323 7.6E-137 T 28-03-2018 IPR024030 AIR synthase-related protein, sll0787 family MKLM6_RS06540 0b1ea2782b737025c477023d8bdcbd32 345 SUPERFAMILY SSF55326 39 155 2.69E-25 T 28-03-2018 IPR016188 PurM-like, N-terminal domain MKLM6_RS06540 0b1ea2782b737025c477023d8bdcbd32 345 PIRSF PIRSF036540 27 326 9.8E-92 T 28-03-2018 IPR011413 Uncharacterised conserved protein UCP036540 MKLM6_RS06540 0b1ea2782b737025c477023d8bdcbd32 345 Pfam PF00586 AIR synthase related protein, N-terminal domain 49 153 3.3E-18 T 28-03-2018 IPR016188 PurM-like, N-terminal domain MKLM6_RS01780 8e3b8c2a9b3ab39add926074c2c4a2e1 201 Pfam PF01323 DSBA-like thioredoxin domain 86 177 4.6E-16 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 MKLM6_RS01780 8e3b8c2a9b3ab39add926074c2c4a2e1 201 SUPERFAMILY SSF52833 34 194 3.21E-43 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS01780 8e3b8c2a9b3ab39add926074c2c4a2e1 201 PIRSF PIRSF001488 1 201 1.7E-51 T 28-03-2018 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL MKLM6_RS01780 8e3b8c2a9b3ab39add926074c2c4a2e1 201 ProSitePatterns PS00194 Thioredoxin family active site. 40 58 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MKLM6_RS01780 8e3b8c2a9b3ab39add926074c2c4a2e1 201 Gene3D G3DSA:3.40.30.10 19 197 4.4E-39 T 28-03-2018 MKLM6_RS20425 6ffa1f7ca79e817edf1cac90ec1f65ba 66 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 65 9.5E-34 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS20425 6ffa1f7ca79e817edf1cac90ec1f65ba 66 ProSitePatterns PS01143 Ribosomal protein L31 signature. 35 56 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS20425 6ffa1f7ca79e817edf1cac90ec1f65ba 66 SUPERFAMILY SSF143800 1 65 2.67E-27 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS20425 6ffa1f7ca79e817edf1cac90ec1f65ba 66 Pfam PF01197 Ribosomal protein L31 1 65 4.8E-32 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS20425 6ffa1f7ca79e817edf1cac90ec1f65ba 66 PRINTS PR01249 Ribosomal protein L31 signature 2 19 5.4E-23 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS20425 6ffa1f7ca79e817edf1cac90ec1f65ba 66 PRINTS PR01249 Ribosomal protein L31 signature 31 46 5.4E-23 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS20425 6ffa1f7ca79e817edf1cac90ec1f65ba 66 PRINTS PR01249 Ribosomal protein L31 signature 46 64 5.4E-23 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS20425 6ffa1f7ca79e817edf1cac90ec1f65ba 66 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 66 28.701 T 28-03-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS21595 1446d19370ecfa68aa0caa9eea0919bc 329 Gene3D G3DSA:3.40.190.10 181 329 2.3E-27 T 28-03-2018 MKLM6_RS21595 1446d19370ecfa68aa0caa9eea0919bc 329 Pfam PF12849 PBP superfamily domain 42 302 9.3E-36 T 28-03-2018 IPR024370 PBP domain MKLM6_RS21595 1446d19370ecfa68aa0caa9eea0919bc 329 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 14 316 2.6E-87 T 28-03-2018 IPR011862 Phosphate binding protein GO:0006810 MKLM6_RS21595 1446d19370ecfa68aa0caa9eea0919bc 329 SUPERFAMILY SSF53850 42 326 2.4E-75 T 28-03-2018 MKLM6_RS21595 1446d19370ecfa68aa0caa9eea0919bc 329 Gene3D G3DSA:3.40.190.10 48 180 5.5E-32 T 28-03-2018 MKLM6_RS07020 53c5c1b2270f2d3ca6200ffcdf382a08 398 Gene3D G3DSA:2.30.130.10 1 74 2.3E-23 T 28-03-2018 IPR002478 PUA domain GO:0003723 MKLM6_RS07020 53c5c1b2270f2d3ca6200ffcdf382a08 398 Gene3D G3DSA:3.30.750.80 78 181 2.1E-31 T 28-03-2018 MKLM6_RS07020 53c5c1b2270f2d3ca6200ffcdf382a08 398 SUPERFAMILY SSF53335 83 391 4.97E-72 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS07020 53c5c1b2270f2d3ca6200ffcdf382a08 398 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 173 353 1.4E-18 T 28-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 MKLM6_RS07020 53c5c1b2270f2d3ca6200ffcdf382a08 398 SMART SM00359 4 92 0.0059 T 28-03-2018 IPR002478 PUA domain GO:0003723 MKLM6_RS07020 53c5c1b2270f2d3ca6200ffcdf382a08 398 Gene3D G3DSA:3.40.50.150 182 398 7.8E-37 T 28-03-2018 MKLM6_RS07020 53c5c1b2270f2d3ca6200ffcdf382a08 398 SUPERFAMILY SSF88697 4 75 1.57E-13 T 28-03-2018 IPR015947 PUA-like domain MKLM6_RS15030 730954c4efb58b2ecd00a3847953c6b1 451 SUPERFAMILY SSF116726 134 217 2.01E-7 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MKLM6_RS15030 730954c4efb58b2ecd00a3847953c6b1 451 SUPERFAMILY SSF51735 231 372 9.97E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS15030 730954c4efb58b2ecd00a3847953c6b1 451 Gene3D G3DSA:3.30.70.1450 137 225 2.7E-10 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MKLM6_RS15030 730954c4efb58b2ecd00a3847953c6b1 451 Gene3D G3DSA:3.30.70.1450 366 451 1.4E-12 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MKLM6_RS15030 730954c4efb58b2ecd00a3847953c6b1 451 SUPERFAMILY SSF51735 1 149 1.58E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS15030 730954c4efb58b2ecd00a3847953c6b1 451 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 9.7E-22 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MKLM6_RS15030 730954c4efb58b2ecd00a3847953c6b1 451 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 9.7E-22 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MKLM6_RS15030 730954c4efb58b2ecd00a3847953c6b1 451 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 9.7E-22 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MKLM6_RS15030 730954c4efb58b2ecd00a3847953c6b1 451 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 9.7E-22 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MKLM6_RS15030 730954c4efb58b2ecd00a3847953c6b1 451 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 9.7E-22 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MKLM6_RS15030 730954c4efb58b2ecd00a3847953c6b1 451 SUPERFAMILY SSF116726 386 440 3.79E-7 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MKLM6_RS15030 730954c4efb58b2ecd00a3847953c6b1 451 Pfam PF02080 TrkA-C domain 387 447 1.9E-8 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MKLM6_RS15030 730954c4efb58b2ecd00a3847953c6b1 451 Gene3D G3DSA:3.40.50.720 226 346 3.9E-14 T 28-03-2018 MKLM6_RS15030 730954c4efb58b2ecd00a3847953c6b1 451 Gene3D G3DSA:3.40.50.720 1 121 7.7E-25 T 28-03-2018 MKLM6_RS15030 730954c4efb58b2ecd00a3847953c6b1 451 Pfam PF02254 TrkA-N domain 3 122 9.4E-28 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MKLM6_RS15030 730954c4efb58b2ecd00a3847953c6b1 451 Pfam PF02254 TrkA-N domain 232 347 2.3E-19 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MKLM6_RS05785 0bf45c4e9e5e64ba63934f14ecd79992 124 Pfam PF07238 PilZ domain 7 104 8.5E-11 T 28-03-2018 IPR009875 PilZ domain GO:0035438 MKLM6_RS05785 0bf45c4e9e5e64ba63934f14ecd79992 124 SUPERFAMILY SSF141371 4 121 1.9E-30 T 28-03-2018 MKLM6_RS05785 0bf45c4e9e5e64ba63934f14ecd79992 124 PIRSF PIRSF028141 4 123 1.3E-36 T 28-03-2018 IPR027021 Cyclic di-GMP binding protein, PA4608 type MKLM6_RS05785 0bf45c4e9e5e64ba63934f14ecd79992 124 Gene3D G3DSA:2.40.10.220 1 123 2.1E-21 T 28-03-2018 MKLM6_RS20045 61e81f4c7742652206a227b846640c63 275 Gene3D G3DSA:3.60.21.10 1 271 1.3E-44 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS20045 61e81f4c7742652206a227b846640c63 275 Hamap MF_00199 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [apaH]. 1 268 44.881 T 28-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 MKLM6_RS20045 61e81f4c7742652206a227b846640c63 275 PIRSF PIRSF000903 1 272 5.4E-107 T 28-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 MKLM6_RS20045 61e81f4c7742652206a227b846640c63 275 SUPERFAMILY SSF56300 1 254 3.14E-54 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS20045 61e81f4c7742652206a227b846640c63 275 Pfam PF00149 Calcineurin-like phosphoesterase 2 163 4.6E-14 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MKLM6_RS20045 61e81f4c7742652206a227b846640c63 275 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 1 256 3.7E-91 T 28-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 MKLM6_RS02505 12178468ad71059201c4629f78e3d58a 362 SMART SM00148 50 190 4.7E-8 T 28-03-2018 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain MKLM6_RS02505 12178468ad71059201c4629f78e3d58a 362 Pfam PF00388 Phosphatidylinositol-specific phospholipase C, X domain 76 186 2.9E-9 T 28-03-2018 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain MKLM6_RS02505 12178468ad71059201c4629f78e3d58a 362 Gene3D G3DSA:3.20.20.190 34 362 6.4E-48 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MKLM6_RS02505 12178468ad71059201c4629f78e3d58a 362 SUPERFAMILY SSF51695 41 260 3.38E-51 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MKLM6_RS02505 12178468ad71059201c4629f78e3d58a 362 SUPERFAMILY SSF51695 318 361 3.38E-51 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MKLM6_RS17710 a0df4be5cde34cf846169a9658f50713 331 SUPERFAMILY SSF53850 31 250 5.37E-48 T 28-03-2018 MKLM6_RS17710 a0df4be5cde34cf846169a9658f50713 331 Gene3D G3DSA:3.40.190.10 27 130 1.8E-18 T 28-03-2018 MKLM6_RS17710 a0df4be5cde34cf846169a9658f50713 331 SMART SM00062 31 245 0.0045 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MKLM6_RS17710 a0df4be5cde34cf846169a9658f50713 331 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 32 324 3.4E-56 T 28-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 MKLM6_RS17710 a0df4be5cde34cf846169a9658f50713 331 Gene3D G3DSA:3.40.190.10 131 327 5.6E-32 T 28-03-2018 MKLM6_RS17710 a0df4be5cde34cf846169a9658f50713 331 Pfam PF09084 NMT1/THI5 like 43 249 4.0E-28 T 28-03-2018 IPR015168 SsuA/THI5-like MKLM6_RS09880 59d50d8e90ffc20339f543fe6ba1cf7a 300 Pfam PF09614 CRISPR-associated protein (Cas_Csy2) 6 289 2.4E-105 T 28-03-2018 IPR013398 CRISPR-associated protein Csy2 MKLM6_RS09880 59d50d8e90ffc20339f543fe6ba1cf7a 300 TIGRFAM TIGR02565 cas_Csy2: CRISPR type I-F/YPEST-associated protein Csy2 5 290 1.7E-64 T 28-03-2018 IPR013398 CRISPR-associated protein Csy2 MKLM6_RS17070 5c2f87ec944dc3d90e3a05683a3b829b 146 SUPERFAMILY SSF81901 35 144 8.5E-18 T 28-03-2018 MKLM6_RS17070 5c2f87ec944dc3d90e3a05683a3b829b 146 Pfam PF08238 Sel1 repeat 71 104 6.4E-7 T 28-03-2018 IPR006597 Sel1-like repeat MKLM6_RS17070 5c2f87ec944dc3d90e3a05683a3b829b 146 Pfam PF08238 Sel1 repeat 41 66 0.15 T 28-03-2018 IPR006597 Sel1-like repeat MKLM6_RS17070 5c2f87ec944dc3d90e3a05683a3b829b 146 Gene3D G3DSA:2.60.40.1180 25 81 1.0E-11 T 28-03-2018 MKLM6_RS17070 5c2f87ec944dc3d90e3a05683a3b829b 146 Gene3D G3DSA:2.60.40.1180 82 145 3.6E-13 T 28-03-2018 MKLM6_RS17070 5c2f87ec944dc3d90e3a05683a3b829b 146 SMART SM00671 70 105 5.0E-7 T 28-03-2018 IPR006597 Sel1-like repeat MKLM6_RS17070 5c2f87ec944dc3d90e3a05683a3b829b 146 SMART SM00671 37 69 71.0 T 28-03-2018 IPR006597 Sel1-like repeat MKLM6_RS04470 29f28ecc973fed76a577164b4b2a009e 448 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 9 308 22.792 T 28-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MKLM6_RS04470 29f28ecc973fed76a577164b4b2a009e 448 Gene3D G3DSA:3.40.50.620 15 224 7.4E-42 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS04470 29f28ecc973fed76a577164b4b2a009e 448 Pfam PF01171 PP-loop family 20 197 1.4E-52 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 MKLM6_RS04470 29f28ecc973fed76a577164b4b2a009e 448 Pfam PF11734 TilS substrate C-terminal domain 364 436 3.2E-22 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MKLM6_RS04470 29f28ecc973fed76a577164b4b2a009e 448 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 20 200 3.7E-48 T 28-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MKLM6_RS04470 29f28ecc973fed76a577164b4b2a009e 448 SMART SM00977 364 436 8.4E-23 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MKLM6_RS04470 29f28ecc973fed76a577164b4b2a009e 448 SUPERFAMILY SSF56037 327 436 2.54E-22 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 MKLM6_RS04470 29f28ecc973fed76a577164b4b2a009e 448 Pfam PF09179 TilS substrate binding domain 248 313 8.5E-6 T 28-03-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MKLM6_RS04470 29f28ecc973fed76a577164b4b2a009e 448 SUPERFAMILY SSF82829 243 317 2.35E-9 T 28-03-2018 MKLM6_RS04470 29f28ecc973fed76a577164b4b2a009e 448 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 365 409 2.6E-15 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MKLM6_RS04470 29f28ecc973fed76a577164b4b2a009e 448 SUPERFAMILY SSF52402 15 228 1.61E-58 T 28-03-2018 MKLM6_RS08415 ce648444e8d07023deb5bd4e678f1a51 297 Gene3D G3DSA:3.40.50.1820 65 293 7.1E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS08415 ce648444e8d07023deb5bd4e678f1a51 297 Pfam PF01738 Dienelactone hydrolase family 85 293 1.3E-50 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 MKLM6_RS08415 ce648444e8d07023deb5bd4e678f1a51 297 SUPERFAMILY SSF53474 70 294 4.88E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS08300 f5b44487196fa5e22aa59ef8e140b265 258 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 52 214 3.5E-48 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MKLM6_RS08300 f5b44487196fa5e22aa59ef8e140b265 258 SUPERFAMILY SSF55068 26 222 1.22E-65 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MKLM6_RS08300 f5b44487196fa5e22aa59ef8e140b265 258 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 49 220 33.451 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MKLM6_RS08300 f5b44487196fa5e22aa59ef8e140b265 258 Gene3D G3DSA:3.30.1060.10 34 224 3.4E-63 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MKLM6_RS08300 f5b44487196fa5e22aa59ef8e140b265 258 Pfam PF01625 Peptide methionine sulfoxide reductase 52 214 3.0E-54 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MKLM6_RS10770 4b9260b82955c8799b241fd33474028f 160 SMART SM00226 4 153 1.1E-53 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily MKLM6_RS10770 4b9260b82955c8799b241fd33474028f 160 SUPERFAMILY SSF52788 2 154 2.35E-53 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily MKLM6_RS10770 4b9260b82955c8799b241fd33474028f 160 Gene3D G3DSA:3.40.50.2300 1 159 2.2E-55 T 28-03-2018 MKLM6_RS10770 4b9260b82955c8799b241fd33474028f 160 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 49 65 2.3E-22 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MKLM6_RS10770 4b9260b82955c8799b241fd33474028f 160 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 83 98 2.3E-22 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MKLM6_RS10770 4b9260b82955c8799b241fd33474028f 160 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 125 140 2.3E-22 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MKLM6_RS10770 4b9260b82955c8799b241fd33474028f 160 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 6 23 2.3E-22 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MKLM6_RS10770 4b9260b82955c8799b241fd33474028f 160 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 6 151 1.2E-42 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily MKLM6_RS02450 2c02556b1433d8bfa061c01af7ee234b 246 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS02450 2c02556b1433d8bfa061c01af7ee234b 246 Pfam PF00005 ABC transporter 27 156 5.7E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS02450 2c02556b1433d8bfa061c01af7ee234b 246 Gene3D G3DSA:3.40.50.300 1 231 6.1E-53 T 28-03-2018 MKLM6_RS02450 2c02556b1433d8bfa061c01af7ee234b 246 SMART SM00382 34 206 5.6E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS02450 2c02556b1433d8bfa061c01af7ee234b 246 SUPERFAMILY SSF52540 24 217 1.42E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS09210 af8b7e31219456cbb4a20f07e1345bb6 145 TIGRFAM TIGR03940 PGA_PgaD: poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD 4 142 4.7E-21 T 28-03-2018 IPR023829 Poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD GO:0042710 MKLM6_RS09210 af8b7e31219456cbb4a20f07e1345bb6 145 Pfam PF13994 PgaD-like protein 5 140 9.7E-24 T 28-03-2018 IPR023829 Poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD GO:0042710 MKLM6_RS06455 f95ea19bb721d86a0202b354a511c28b 175 Gene3D G3DSA:1.10.10.10 77 167 3.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS06455 f95ea19bb721d86a0202b354a511c28b 175 SUPERFAMILY SSF88946 7 89 1.18E-12 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS06455 f95ea19bb721d86a0202b354a511c28b 175 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 163 5.7E-22 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS06455 f95ea19bb721d86a0202b354a511c28b 175 Pfam PF08281 Sigma-70, region 4 108 156 6.0E-9 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS06455 f95ea19bb721d86a0202b354a511c28b 175 SUPERFAMILY SSF88659 88 163 5.23E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS06455 f95ea19bb721d86a0202b354a511c28b 175 Gene3D G3DSA:1.10.1740.10 4 76 3.9E-13 T 28-03-2018 MKLM6_RS06455 f95ea19bb721d86a0202b354a511c28b 175 Pfam PF04542 Sigma-70 region 2 10 68 2.5E-9 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS20740 168bef0e8ca2d3fe79f474b8c75a9bf8 502 SMART SM00382 210 392 0.0068 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS20740 168bef0e8ca2d3fe79f474b8c75a9bf8 502 Gene3D G3DSA:3.40.50.300 187 457 4.3E-22 T 28-03-2018 MKLM6_RS20740 168bef0e8ca2d3fe79f474b8c75a9bf8 502 SUPERFAMILY SSF54211 10 169 9.48E-33 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS20740 168bef0e8ca2d3fe79f474b8c75a9bf8 502 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 405 496 8.8E-30 T 28-03-2018 IPR025158 Mg chelatase-related protein, C-terminal domain MKLM6_RS20740 168bef0e8ca2d3fe79f474b8c75a9bf8 502 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 6 496 8.6E-191 T 28-03-2018 IPR004482 Mg chelatase-related protein MKLM6_RS20740 168bef0e8ca2d3fe79f474b8c75a9bf8 502 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 139 1.9E-45 T 28-03-2018 MKLM6_RS20740 168bef0e8ca2d3fe79f474b8c75a9bf8 502 SUPERFAMILY SSF52540 188 500 2.03E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS20740 168bef0e8ca2d3fe79f474b8c75a9bf8 502 Gene3D G3DSA:3.30.230.10 2 186 6.9E-41 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MKLM6_RS20740 168bef0e8ca2d3fe79f474b8c75a9bf8 502 Pfam PF01078 Magnesium chelatase, subunit ChlI 190 394 2.1E-96 T 28-03-2018 IPR000523 Magnesium chelatase ChlI domain MKLM6_RS20740 168bef0e8ca2d3fe79f474b8c75a9bf8 502 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 209 224 1.4E-6 T 28-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 MKLM6_RS20740 168bef0e8ca2d3fe79f474b8c75a9bf8 502 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 317 330 1.4E-6 T 28-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 MKLM6_RS20740 168bef0e8ca2d3fe79f474b8c75a9bf8 502 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 289 303 1.4E-6 T 28-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 MKLM6_RS20740 168bef0e8ca2d3fe79f474b8c75a9bf8 502 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 341 353 1.4E-6 T 28-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 MKLM6_RS03300 303c9f53e3936faebdd039939469cf69 125 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 9 96 2.7E-24 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 MKLM6_RS03300 303c9f53e3936faebdd039939469cf69 125 Gene3D G3DSA:3.30.1360.20 2 100 4.3E-24 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 MKLM6_RS03300 303c9f53e3936faebdd039939469cf69 125 SUPERFAMILY SSF55248 11 99 8.24E-27 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 MKLM6_RS05210 92c98e34197929e08991d52b4a925cc8 135 PRINTS PR01651 Protein-export SecG membrane protein signature 55 77 3.5E-36 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MKLM6_RS05210 92c98e34197929e08991d52b4a925cc8 135 PRINTS PR01651 Protein-export SecG membrane protein signature 24 38 3.5E-36 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MKLM6_RS05210 92c98e34197929e08991d52b4a925cc8 135 PRINTS PR01651 Protein-export SecG membrane protein signature 4 24 3.5E-36 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MKLM6_RS05210 92c98e34197929e08991d52b4a925cc8 135 PRINTS PR01651 Protein-export SecG membrane protein signature 39 55 3.5E-36 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MKLM6_RS05210 92c98e34197929e08991d52b4a925cc8 135 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 74 4.3E-25 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MKLM6_RS05210 92c98e34197929e08991d52b4a925cc8 135 Pfam PF03840 Preprotein translocase SecG subunit 5 74 5.3E-20 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MKLM6_RS01945 bcfedf2be4f174ba65409b85f9872cbe 240 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 240 45.218 T 28-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MKLM6_RS01945 bcfedf2be4f174ba65409b85f9872cbe 240 Pfam PF02654 Cobalamin-5-phosphate synthase 7 234 2.1E-54 T 28-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MKLM6_RS14425 9e1634646b35739ed403ec263ac819b5 361 SUPERFAMILY SSF111369 45 261 6.28E-44 T 28-03-2018 MKLM6_RS14425 9e1634646b35739ed403ec263ac819b5 361 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 37 344 2.7E-60 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MKLM6_RS14425 9e1634646b35739ed403ec263ac819b5 361 Gene3D G3DSA:2.40.50.100 147 344 2.0E-4 T 28-03-2018 MKLM6_RS14425 9e1634646b35739ed403ec263ac819b5 361 Gene3D G3DSA:1.10.287.470 92 146 7.2E-7 T 28-03-2018 MKLM6_RS14425 9e1634646b35739ed403ec263ac819b5 361 Gene3D G3DSA:2.40.50.100 41 91 1.1E-4 T 28-03-2018 MKLM6_RS14425 9e1634646b35739ed403ec263ac819b5 361 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 60 261 1.6E-19 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MKLM6_RS13905 6cde4e4dbea898d9360e49158f3b422b 404 Gene3D G3DSA:3.40.30.10 28 134 2.4E-6 T 28-03-2018 MKLM6_RS13905 6cde4e4dbea898d9360e49158f3b422b 404 SUPERFAMILY SSF52833 37 125 1.09E-6 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS21615 07410d5a587c5d007287d9968a31a8cb 209 Gene3D G3DSA:3.30.70.1070 129 208 1.8E-13 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 MKLM6_RS21615 07410d5a587c5d007287d9968a31a8cb 209 Pfam PF05036 Sporulation related domain 134 204 1.7E-11 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 MKLM6_RS21615 07410d5a587c5d007287d9968a31a8cb 209 SUPERFAMILY SSF110997 133 201 6.15E-14 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 MKLM6_RS20460 21aed04fc1a688476ed8b9582cbf8079 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 1.9E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MKLM6_RS20460 21aed04fc1a688476ed8b9582cbf8079 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 1.9E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MKLM6_RS20460 21aed04fc1a688476ed8b9582cbf8079 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 22 37 1.9E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MKLM6_RS20460 21aed04fc1a688476ed8b9582cbf8079 103 Gene3D G3DSA:1.10.10.10 1 97 5.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS20460 21aed04fc1a688476ed8b9582cbf8079 103 Pfam PF01022 Bacterial regulatory protein, arsR family 27 72 5.4E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MKLM6_RS20460 21aed04fc1a688476ed8b9582cbf8079 103 SMART SM00418 20 98 1.2E-22 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MKLM6_RS20460 21aed04fc1a688476ed8b9582cbf8079 103 SUPERFAMILY SSF46785 9 101 1.19E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS18965 21eb3ad15d4ced9f7d9498fa60a92c63 410 SUPERFAMILY SSF58104 100 353 5.36E-39 T 28-03-2018 MKLM6_RS18965 21eb3ad15d4ced9f7d9498fa60a92c63 410 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 238 267 2.5E-15 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MKLM6_RS18965 21eb3ad15d4ced9f7d9498fa60a92c63 410 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 209 236 2.5E-15 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MKLM6_RS18965 21eb3ad15d4ced9f7d9498fa60a92c63 410 Gene3D G3DSA:1.10.287.950 62 329 2.7E-33 T 28-03-2018 MKLM6_RS18965 21eb3ad15d4ced9f7d9498fa60a92c63 410 SMART SM00283 99 362 2.0E-6 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS18965 21eb3ad15d4ced9f7d9498fa60a92c63 410 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 181 326 1.9E-27 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS17315 97b8b4f8a05f037085b0b719d0f837ae 306 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 106 305 1.6E-8 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 MKLM6_RS17315 97b8b4f8a05f037085b0b719d0f837ae 306 PIRSF PIRSF028561 2 306 4.0E-88 T 28-03-2018 IPR014548 Predicted acyltransferase MKLM6_RS03045 41a130e53bdf13465d8015121df23df9 242 Gene3D G3DSA:3.40.1280.10 1 242 3.6E-76 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MKLM6_RS03045 41a130e53bdf13465d8015121df23df9 242 PIRSF PIRSF015601 2 240 9.2E-57 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MKLM6_RS03045 41a130e53bdf13465d8015121df23df9 242 SUPERFAMILY SSF75217 74 241 7.41E-50 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases MKLM6_RS03045 41a130e53bdf13465d8015121df23df9 242 SUPERFAMILY SSF88697 3 69 2.31E-14 T 28-03-2018 IPR015947 PUA-like domain MKLM6_RS03045 41a130e53bdf13465d8015121df23df9 242 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 16 240 6.4E-59 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MKLM6_RS03045 41a130e53bdf13465d8015121df23df9 242 Pfam PF04452 RNA methyltransferase 18 235 1.3E-68 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MKLM6_RS20550 e85e8159bf42685edf3921165d3fad9d 408 Gene3D G3DSA:3.90.640.10 249 300 1.9E-21 T 28-03-2018 MKLM6_RS20550 e85e8159bf42685edf3921165d3fad9d 408 SUPERFAMILY SSF53067 198 378 1.09E-50 T 28-03-2018 MKLM6_RS20550 e85e8159bf42685edf3921165d3fad9d 408 Hamap MF_02033 Cell division protein FtsA [ftsA]. 6 408 31.917 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 MKLM6_RS20550 e85e8159bf42685edf3921165d3fad9d 408 Gene3D G3DSA:3.30.420.40 197 248 2.6E-7 T 28-03-2018 MKLM6_RS20550 e85e8159bf42685edf3921165d3fad9d 408 Gene3D G3DSA:3.30.420.40 2 187 1.2E-39 T 28-03-2018 MKLM6_RS20550 e85e8159bf42685edf3921165d3fad9d 408 SUPERFAMILY SSF53067 9 197 8.85E-61 T 28-03-2018 MKLM6_RS20550 e85e8159bf42685edf3921165d3fad9d 408 Pfam PF14450 Cell division protein FtsA 207 374 1.0E-26 T 28-03-2018 MKLM6_RS20550 e85e8159bf42685edf3921165d3fad9d 408 Pfam PF14450 Cell division protein FtsA 11 180 5.2E-12 T 28-03-2018 MKLM6_RS20550 e85e8159bf42685edf3921165d3fad9d 408 SMART SM00842 10 196 7.4E-103 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 MKLM6_RS20550 e85e8159bf42685edf3921165d3fad9d 408 Pfam PF02491 SHS2 domain inserted in FTSA 85 162 7.7E-34 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 MKLM6_RS20550 e85e8159bf42685edf3921165d3fad9d 408 PIRSF PIRSF003101 1 408 3.5E-157 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 MKLM6_RS20550 e85e8159bf42685edf3921165d3fad9d 408 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 10 378 1.7E-155 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 MKLM6_RS19630 708c4c15012b95792bd19b5c90d5ea00 731 Gene3D G3DSA:3.30.750.80 413 518 2.4E-4 T 28-03-2018 MKLM6_RS19630 708c4c15012b95792bd19b5c90d5ea00 731 Pfam PF02926 THUMP domain 25 156 3.0E-12 T 28-03-2018 IPR004114 THUMP domain GO:0003723 MKLM6_RS19630 708c4c15012b95792bd19b5c90d5ea00 731 PIRSF PIRSF037618 1 731 3.1E-298 T 28-03-2018 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MKLM6_RS19630 708c4c15012b95792bd19b5c90d5ea00 731 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 506 684 2.1E-20 T 28-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 MKLM6_RS19630 708c4c15012b95792bd19b5c90d5ea00 731 Hamap MF_01858 Ribosomal RNA large subunit methyltransferase K/L [rlmL]. 6 731 32.131 T 28-03-2018 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MKLM6_RS19630 708c4c15012b95792bd19b5c90d5ea00 731 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 311 317 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MKLM6_RS19630 708c4c15012b95792bd19b5c90d5ea00 731 SUPERFAMILY SSF53335 148 224 2.11E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS19630 708c4c15012b95792bd19b5c90d5ea00 731 SUPERFAMILY SSF53335 264 380 2.11E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS19630 708c4c15012b95792bd19b5c90d5ea00 731 Pfam PF01170 Putative RNA methylase family UPF0020 165 379 1.8E-44 T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MKLM6_RS19630 708c4c15012b95792bd19b5c90d5ea00 731 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 202 213 - T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MKLM6_RS19630 708c4c15012b95792bd19b5c90d5ea00 731 SUPERFAMILY SSF53335 420 728 1.31E-60 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS19630 708c4c15012b95792bd19b5c90d5ea00 731 Gene3D G3DSA:3.40.50.150 163 394 6.3E-27 T 28-03-2018 MKLM6_RS19630 708c4c15012b95792bd19b5c90d5ea00 731 Gene3D G3DSA:3.40.50.150 519 731 2.7E-39 T 28-03-2018 MKLM6_RS19630 708c4c15012b95792bd19b5c90d5ea00 731 SMART SM00981 58 157 9.3E-19 T 28-03-2018 IPR004114 THUMP domain GO:0003723 MKLM6_RS03930 e7c1698ea3c87d2079c9dafeb9d7b35c 242 SMART SM00849 28 217 9.6E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS03930 e7c1698ea3c87d2079c9dafeb9d7b35c 242 Gene3D G3DSA:3.60.15.10 2 241 7.4E-24 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS03930 e7c1698ea3c87d2079c9dafeb9d7b35c 242 Pfam PF00753 Metallo-beta-lactamase superfamily 29 217 2.6E-18 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS03930 e7c1698ea3c87d2079c9dafeb9d7b35c 242 SUPERFAMILY SSF56281 22 235 2.03E-31 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS19835 307db2c83211b6019f6aa4a2acdb5bf2 200 SUPERFAMILY SSF52266 21 195 2.29E-51 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain MKLM6_RS19835 307db2c83211b6019f6aa4a2acdb5bf2 200 ProSitePatterns PS01098 Lipolytic enzymes "G-D-S-L" family, serine active site. 22 32 - T 28-03-2018 IPR008265 Lipase, GDSL, active site GO:0006629|GO:0016298 Reactome: R-HSA-1482788|Reactome: R-HSA-975634 MKLM6_RS19835 307db2c83211b6019f6aa4a2acdb5bf2 200 Gene3D G3DSA:3.40.50.1110 18 200 9.6E-40 T 28-03-2018 MKLM6_RS19835 307db2c83211b6019f6aa4a2acdb5bf2 200 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 24 182 3.8E-23 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain MKLM6_RS17720 57ad9e9045b56c75fca797d92550cb7d 317 Gene3D G3DSA:1.20.1170.10 51 242 7.7E-5 T 28-03-2018 MKLM6_RS13625 c0f38476bdc12ae5357ed1d953684004 616 Gene3D G3DSA:3.40.50.2300 87 247 1.4E-4 T 28-03-2018 MKLM6_RS13625 c0f38476bdc12ae5357ed1d953684004 616 SUPERFAMILY SSF143975 4 421 2.35E-135 T 28-03-2018 MKLM6_RS13625 c0f38476bdc12ae5357ed1d953684004 616 SUPERFAMILY SSF52016 422 610 3.14E-60 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MKLM6_RS13625 c0f38476bdc12ae5357ed1d953684004 616 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 609 3.0E-253 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MKLM6_RS13625 c0f38476bdc12ae5357ed1d953684004 616 Pfam PF00920 Dehydratase family 34 606 2.2E-219 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MKLM6_RS13625 c0f38476bdc12ae5357ed1d953684004 616 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 510 521 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MKLM6_RS13625 c0f38476bdc12ae5357ed1d953684004 616 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MKLM6_RS13625 c0f38476bdc12ae5357ed1d953684004 616 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 609 44.583 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MKLM6_RS14615 3e91973d9b0b55ca612fed34c064a521 147 Gene3D G3DSA:3.30.450.30 30 146 4.4E-8 T 28-03-2018 MKLM6_RS14615 3e91973d9b0b55ca612fed34c064a521 147 SMART SM00960 47 133 0.0013 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain MKLM6_RS14615 3e91973d9b0b55ca612fed34c064a521 147 SUPERFAMILY SSF103196 51 141 3.31E-7 T 28-03-2018 MKLM6_RS12570 a2c3f1d215c3948e6efdca476f1c6983 148 Gene3D G3DSA:1.10.940.10 1 137 5.4E-42 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MKLM6_RS12570 a2c3f1d215c3948e6efdca476f1c6983 148 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 5 132 1.2E-42 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 MKLM6_RS12570 a2c3f1d215c3948e6efdca476f1c6983 148 Pfam PF01029 NusB family 7 130 5.7E-36 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MKLM6_RS12570 a2c3f1d215c3948e6efdca476f1c6983 148 SUPERFAMILY SSF48013 4 133 7.59E-42 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MKLM6_RS12570 a2c3f1d215c3948e6efdca476f1c6983 148 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 3 134 21.361 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 MKLM6_RS11410 101bcd16fb780ec87c87770763aa0e0a 425 Gene3D G3DSA:1.20.1250.20 7 228 2.4E-24 T 28-03-2018 MKLM6_RS11410 101bcd16fb780ec87c87770763aa0e0a 425 Pfam PF07690 Major Facilitator Superfamily 18 371 1.1E-19 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MKLM6_RS11410 101bcd16fb780ec87c87770763aa0e0a 425 TIGRFAM TIGR01272 gluP: glucose/galactose transporter WARNING 92 412 1.1E-108 T 28-03-2018 IPR005964 Bacterial glucose/galactose transporter GO:0005354|GO:0005355|GO:0009276|GO:0015757|GO:0015758|GO:0016021 MKLM6_RS11410 101bcd16fb780ec87c87770763aa0e0a 425 Gene3D G3DSA:1.20.1250.20 234 420 1.6E-17 T 28-03-2018 MKLM6_RS11410 101bcd16fb780ec87c87770763aa0e0a 425 SUPERFAMILY SSF103473 9 415 1.44E-39 T 28-03-2018 IPR020846 Major facilitator superfamily domain MKLM6_RS05320 2fd75d558206821f18de3630fc976d76 331 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 311 327 7.9E-9 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MKLM6_RS05320 2fd75d558206821f18de3630fc976d76 331 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 296 311 7.9E-9 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MKLM6_RS05320 2fd75d558206821f18de3630fc976d76 331 Pfam PF12833 Helix-turn-helix domain 248 328 2.6E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MKLM6_RS05320 2fd75d558206821f18de3630fc976d76 331 SUPERFAMILY SSF46689 278 328 3.67E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS05320 2fd75d558206821f18de3630fc976d76 331 Gene3D G3DSA:2.60.120.10 6 159 1.0E-5 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS05320 2fd75d558206821f18de3630fc976d76 331 SMART SM00342 242 327 3.1E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MKLM6_RS05320 2fd75d558206821f18de3630fc976d76 331 Gene3D G3DSA:1.10.10.60 279 330 4.2E-15 T 28-03-2018 MKLM6_RS05320 2fd75d558206821f18de3630fc976d76 331 Pfam PF14525 AraC-binding-like domain 36 209 5.2E-24 T 28-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like MKLM6_RS05320 2fd75d558206821f18de3630fc976d76 331 SUPERFAMILY SSF51182 58 146 4.66E-7 T 28-03-2018 IPR011051 RmlC-like cupin domain MKLM6_RS05320 2fd75d558206821f18de3630fc976d76 331 Gene3D G3DSA:1.10.10.60 220 278 1.2E-7 T 28-03-2018 MKLM6_RS02020 8d7e27deed1b312b00eabd502fe2f894 362 SUPERFAMILY SSF111369 34 284 1.12E-21 T 28-03-2018 MKLM6_RS02020 8d7e27deed1b312b00eabd502fe2f894 362 Pfam PF13437 HlyD family secretion protein 159 274 8.0E-7 T 28-03-2018 MKLM6_RS02020 8d7e27deed1b312b00eabd502fe2f894 362 Gene3D G3DSA:1.20.1600.10 63 267 1.5E-16 T 28-03-2018 MKLM6_RS02020 8d7e27deed1b312b00eabd502fe2f894 362 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 20 357 5.4E-41 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MKLM6_RS01940 3ad7fe379223fb883b3516a5ec4dae82 137 Pfam PF05154 TM2 domain 69 119 8.3E-10 T 28-03-2018 IPR007829 TM2 domain MKLM6_RS04675 30083280e3ef70c03f79d427c2f64254 394 SUPERFAMILY SSF110296 4 82 1.06E-51 T 28-03-2018 MKLM6_RS04675 30083280e3ef70c03f79d427c2f64254 394 SUPERFAMILY SSF110296 189 391 1.06E-51 T 28-03-2018 MKLM6_RS04675 30083280e3ef70c03f79d427c2f64254 394 SUPERFAMILY SSF110296 109 156 1.06E-51 T 28-03-2018 MKLM6_RS04675 30083280e3ef70c03f79d427c2f64254 394 Gene3D G3DSA:2.130.10.10 2 394 3.5E-61 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MKLM6_RS11815 e45026941e21e194f01f17e50c85de0d 173 Pfam PF08212 Lipocalin-like domain 31 169 2.6E-41 T 28-03-2018 IPR000566 Lipocalin/cytosolic fatty-acid binding domain MKLM6_RS11815 e45026941e21e194f01f17e50c85de0d 173 PRINTS PR01171 Bacterial lipocalin signature 66 75 1.8E-32 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 MKLM6_RS11815 e45026941e21e194f01f17e50c85de0d 173 PRINTS PR01171 Bacterial lipocalin signature 133 144 1.8E-32 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 MKLM6_RS11815 e45026941e21e194f01f17e50c85de0d 173 PRINTS PR01171 Bacterial lipocalin signature 30 44 1.8E-32 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 MKLM6_RS11815 e45026941e21e194f01f17e50c85de0d 173 PRINTS PR01171 Bacterial lipocalin signature 160 170 1.8E-32 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 MKLM6_RS11815 e45026941e21e194f01f17e50c85de0d 173 PRINTS PR01171 Bacterial lipocalin signature 100 114 1.8E-32 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 MKLM6_RS11815 e45026941e21e194f01f17e50c85de0d 173 PRINTS PR01171 Bacterial lipocalin signature 47 63 1.8E-32 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 MKLM6_RS11815 e45026941e21e194f01f17e50c85de0d 173 SUPERFAMILY SSF50814 6 168 8.11E-46 T 28-03-2018 IPR012674 Calycin MKLM6_RS11815 e45026941e21e194f01f17e50c85de0d 173 PIRSF PIRSF036893 1 173 7.5E-44 T 28-03-2018 IPR022271 Lipocalin, ApoD type MKLM6_RS11815 e45026941e21e194f01f17e50c85de0d 173 ProSitePatterns PS00213 Lipocalin signature. 29 42 - T 28-03-2018 IPR022272 Lipocalin family conserved site MKLM6_RS11815 e45026941e21e194f01f17e50c85de0d 173 Gene3D G3DSA:2.40.128.20 1 170 5.8E-38 T 28-03-2018 IPR012674 Calycin MKLM6_RS03260 cd7e2bb6605e0a5d70684d2635ebd35b 271 Gene3D G3DSA:2.160.20.60 83 230 1.3E-29 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 MKLM6_RS03260 cd7e2bb6605e0a5d70684d2635ebd35b 271 SUPERFAMILY SSF69336 15 213 1.01E-41 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 MKLM6_RS03260 cd7e2bb6605e0a5d70684d2635ebd35b 271 Pfam PF01493 GXGXG motif 82 210 2.0E-16 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 MKLM6_RS03260 cd7e2bb6605e0a5d70684d2635ebd35b 271 TIGRFAM TIGR03122 one_C_dehyd_C: formylmethanofuran dehydrogenase subunit C 10 269 1.2E-80 T 28-03-2018 IPR017550 Formylmethanofuran dehydrogenase subunit C GO:0015948|GO:0018493|GO:0046914|GO:0055114 KEGG: 00680+1.2.99.5|MetaCyc: PWY-5209|MetaCyc: PWY-7784 MKLM6_RS06990 31d652ff2bad9184f050be296d415cf0 177 SUPERFAMILY SSF52833 1 174 4.01E-37 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS06990 31d652ff2bad9184f050be296d415cf0 177 Gene3D G3DSA:3.40.30.10 23 177 7.6E-33 T 28-03-2018 MKLM6_RS06990 31d652ff2bad9184f050be296d415cf0 177 ProSitePatterns PS00194 Thioredoxin family active site. 64 82 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MKLM6_RS06990 31d652ff2bad9184f050be296d415cf0 177 Pfam PF08534 Redoxin 42 163 9.0E-22 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 MKLM6_RS07645 11818903695c9c0fd9ac73e0abfb00ec 154 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 3 146 7.0E-24 T 28-03-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 MKLM6_RS07645 11818903695c9c0fd9ac73e0abfb00ec 154 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 4 141 2.3E-32 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 MKLM6_RS07645 11818903695c9c0fd9ac73e0abfb00ec 154 Gene3D G3DSA:3.60.21.10 2 153 3.4E-18 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS07645 11818903695c9c0fd9ac73e0abfb00ec 154 SUPERFAMILY SSF56300 3 152 2.57E-34 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS01665 563f9318a62076c3461af912199b9293 509 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 28 477 3.9E-91 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 MKLM6_RS01665 563f9318a62076c3461af912199b9293 509 Gene3D G3DSA:1.20.1600.10 27 483 2.2E-77 T 28-03-2018 MKLM6_RS01665 563f9318a62076c3461af912199b9293 509 Pfam PF02321 Outer membrane efflux protein 77 260 4.2E-14 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS01665 563f9318a62076c3461af912199b9293 509 Pfam PF02321 Outer membrane efflux protein 297 475 1.4E-23 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS01665 563f9318a62076c3461af912199b9293 509 SUPERFAMILY SSF56954 2 37 4.05E-82 T 28-03-2018 MKLM6_RS01665 563f9318a62076c3461af912199b9293 509 SUPERFAMILY SSF56954 67 479 4.05E-82 T 28-03-2018 MKLM6_RS08125 17a525af59e76229b0f9b95ee7f7f5f4 363 Pfam PF00534 Glycosyl transferases group 1 175 333 1.4E-28 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 MKLM6_RS08125 17a525af59e76229b0f9b95ee7f7f5f4 363 Gene3D G3DSA:3.40.50.2000 156 339 5.6E-34 T 28-03-2018 MKLM6_RS08125 17a525af59e76229b0f9b95ee7f7f5f4 363 SUPERFAMILY SSF53756 8 357 2.3E-53 T 28-03-2018 MKLM6_RS00470 5925c4797e5f467faffbacc58816a3e8 197 Pfam PF03358 NADPH-dependent FMN reductase 4 128 4.5E-11 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 MKLM6_RS00470 5925c4797e5f467faffbacc58816a3e8 197 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 28-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 MKLM6_RS00470 5925c4797e5f467faffbacc58816a3e8 197 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 2 171 5.8E-42 T 28-03-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 MKLM6_RS00470 5925c4797e5f467faffbacc58816a3e8 197 SUPERFAMILY SSF52218 1 194 6.16E-58 T 28-03-2018 IPR029039 Flavoprotein-like domain MKLM6_RS00470 5925c4797e5f467faffbacc58816a3e8 197 Gene3D G3DSA:3.40.50.360 1 197 1.9E-38 T 28-03-2018 IPR029039 Flavoprotein-like domain MKLM6_RS21720 2850854316d3c70edaa58f5d9645f997 210 Pfam PF13835 Domain of unknown function (DUF4194) 20 188 3.0E-46 T 28-03-2018 IPR025449 Protein of unknown function DUF4194 MKLM6_RS21290 5b8850af64b8ac9ec3cacf32671eb129 794 PIRSF PIRSF001227 10 784 4.9E-174 T 28-03-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 MKLM6_RS21290 5b8850af64b8ac9ec3cacf32671eb129 794 SUPERFAMILY SSF56235 46 785 7.2E-183 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MKLM6_RS21290 5b8850af64b8ac9ec3cacf32671eb129 794 Gene3D G3DSA:3.60.20.10 264 789 3.9E-98 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MKLM6_RS21290 5b8850af64b8ac9ec3cacf32671eb129 794 Pfam PF01804 Penicillin amidase 49 778 9.5E-163 T 28-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 MKLM6_RS21290 5b8850af64b8ac9ec3cacf32671eb129 794 Gene3D G3DSA:1.10.439.10 19 181 5.7E-48 T 28-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 MKLM6_RS17040 d82684429542897bca8fe54657a1640a 497 Gene3D G3DSA:3.30.420.130 363 487 7.1E-31 T 28-03-2018 MKLM6_RS17040 d82684429542897bca8fe54657a1640a 497 Pfam PF04055 Radical SAM superfamily 61 240 3.8E-27 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS17040 d82684429542897bca8fe54657a1640a 497 Gene3D G3DSA:3.20.20.70 45 355 5.0E-31 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS17040 d82684429542897bca8fe54657a1640a 497 SUPERFAMILY SSF53146 368 480 7.19E-30 T 28-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis MKLM6_RS17040 d82684429542897bca8fe54657a1640a 497 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 380 477 5.6E-20 T 28-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis MKLM6_RS17040 d82684429542897bca8fe54657a1640a 497 TIGRFAM TIGR01290 nifB: nitrogenase cofactor biosynthesis protein NifB 34 478 2.1E-197 T 28-03-2018 IPR005980 Nitrogenase cofactor biosynthesis protein NifB GO:0009108|GO:0009399 MKLM6_RS17040 d82684429542897bca8fe54657a1640a 497 SUPERFAMILY SSF102114 50 261 3.14E-37 T 28-03-2018 MKLM6_RS17040 d82684429542897bca8fe54657a1640a 497 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 61 72 - T 28-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 MKLM6_RS14610 d3075a3d8f52c3ad19f10fcb5ab4f2cc 229 SUPERFAMILY SSF53098 6 202 2.35E-52 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS14610 d3075a3d8f52c3ad19f10fcb5ab4f2cc 229 Pfam PF00929 Exonuclease 18 192 2.8E-27 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MKLM6_RS14610 d3075a3d8f52c3ad19f10fcb5ab4f2cc 229 TIGRFAM TIGR01298 RNaseT: ribonuclease T 9 203 2.2E-87 T 28-03-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 MKLM6_RS14610 d3075a3d8f52c3ad19f10fcb5ab4f2cc 229 Hamap MF_00157 Ribonuclease T [rnt]. 1 229 90.115 T 28-03-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 MKLM6_RS14610 d3075a3d8f52c3ad19f10fcb5ab4f2cc 229 SMART SM00479 16 201 1.5E-20 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MKLM6_RS14610 d3075a3d8f52c3ad19f10fcb5ab4f2cc 229 Gene3D G3DSA:3.30.420.10 17 184 5.3E-27 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS14610 d3075a3d8f52c3ad19f10fcb5ab4f2cc 229 Gene3D G3DSA:1.20.5.140 185 202 6.0E-4 T 28-03-2018 MKLM6_RS05695 701c5caf6c4162bc2163c453fe40c167 264 SUPERFAMILY SSF56601 27 243 2.47E-33 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MKLM6_RS05695 701c5caf6c4162bc2163c453fe40c167 264 Gene3D G3DSA:3.40.710.10 22 259 5.3E-31 T 28-03-2018 MKLM6_RS05695 701c5caf6c4162bc2163c453fe40c167 264 Pfam PF00905 Penicillin binding protein transpeptidase domain 61 257 1.6E-31 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MKLM6_RS04855 4a8e6786ca25c7b923da7056ba2fb81c 83 Gene3D G3DSA:3.30.1320.10 1 79 1.5E-33 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS04855 4a8e6786ca25c7b923da7056ba2fb81c 83 ProSitePatterns PS00732 Ribosomal protein S16 signature. 2 11 - T 28-03-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS04855 4a8e6786ca25c7b923da7056ba2fb81c 83 SUPERFAMILY SSF54565 1 78 2.35E-30 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS04855 4a8e6786ca25c7b923da7056ba2fb81c 83 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 78 5.0E-29 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS04855 4a8e6786ca25c7b923da7056ba2fb81c 83 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 24.484 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS04855 4a8e6786ca25c7b923da7056ba2fb81c 83 Pfam PF00886 Ribosomal protein S16 8 68 9.4E-26 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS10245 dee16f487309b29e6ca59dd9423c90f6 203 SUPERFAMILY SSF52540 48 160 3.36E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS10245 dee16f487309b29e6ca59dd9423c90f6 203 Gene3D G3DSA:3.40.50.300 47 162 4.9E-32 T 28-03-2018 MKLM6_RS10245 dee16f487309b29e6ca59dd9423c90f6 203 PIRSF PIRSF037290 2 203 9.1E-61 T 28-03-2018 IPR017166 Uncharacterised conserved protein UCP037290 MKLM6_RS17145 3c4f744fdfd55131aca8bb5adbd09edb 342 Gene3D G3DSA:1.10.287.470 128 170 1.1E-7 T 28-03-2018 MKLM6_RS17145 3c4f744fdfd55131aca8bb5adbd09edb 342 SUPERFAMILY SSF111369 179 291 9.15E-7 T 28-03-2018 MKLM6_RS17145 3c4f744fdfd55131aca8bb5adbd09edb 342 Gene3D G3DSA:1.20.1600.10 178 331 7.5E-15 T 28-03-2018 MKLM6_RS17145 3c4f744fdfd55131aca8bb5adbd09edb 342 Gene3D G3DSA:2.40.50.100 44 127 1.1E-8 T 28-03-2018 MKLM6_RS17145 3c4f744fdfd55131aca8bb5adbd09edb 342 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 54 288 2.7E-14 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MKLM6_RS08245 d58b5888a15285bdbdceb6117cac9483 552 Pfam PF03929 PepSY-associated TM region 12 314 1.4E-11 T 28-03-2018 IPR005625 PepSY-associated TM protein MKLM6_RS21940 7d8e8d0e81615ebe0aa9e2e9393d72b4 169 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 18 163 4.1E-31 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 MKLM6_RS21940 7d8e8d0e81615ebe0aa9e2e9393d72b4 169 Gene3D G3DSA:3.30.530.20 3 168 2.9E-27 T 28-03-2018 IPR023393 START-like domain MKLM6_RS21940 7d8e8d0e81615ebe0aa9e2e9393d72b4 169 SUPERFAMILY SSF55961 5 164 1.07E-41 T 28-03-2018 MKLM6_RS14475 343fedd3fabb4da9ecdbb4fb5756634d 450 Pfam PF01609 Transposase DDE domain 274 441 3.7E-21 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS14475 343fedd3fabb4da9ecdbb4fb5756634d 450 Pfam PF05598 Transposase domain (DUF772) 52 121 7.8E-15 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS14475 343fedd3fabb4da9ecdbb4fb5756634d 450 Gene3D G3DSA:3.90.350.10 270 407 2.1E-6 T 28-03-2018 IPR014736 Transposase, Tn5-like, core MKLM6_RS13045 343fedd3fabb4da9ecdbb4fb5756634d 450 Pfam PF01609 Transposase DDE domain 274 441 3.7E-21 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS13045 343fedd3fabb4da9ecdbb4fb5756634d 450 Pfam PF05598 Transposase domain (DUF772) 52 121 7.8E-15 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS13045 343fedd3fabb4da9ecdbb4fb5756634d 450 Gene3D G3DSA:3.90.350.10 270 407 2.1E-6 T 28-03-2018 IPR014736 Transposase, Tn5-like, core MKLM6_RS21885 343fedd3fabb4da9ecdbb4fb5756634d 450 Pfam PF01609 Transposase DDE domain 274 441 3.7E-21 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS21885 343fedd3fabb4da9ecdbb4fb5756634d 450 Pfam PF05598 Transposase domain (DUF772) 52 121 7.8E-15 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS21885 343fedd3fabb4da9ecdbb4fb5756634d 450 Gene3D G3DSA:3.90.350.10 270 407 2.1E-6 T 28-03-2018 IPR014736 Transposase, Tn5-like, core MKLM6_RS19470 343fedd3fabb4da9ecdbb4fb5756634d 450 Pfam PF01609 Transposase DDE domain 274 441 3.7E-21 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS19470 343fedd3fabb4da9ecdbb4fb5756634d 450 Pfam PF05598 Transposase domain (DUF772) 52 121 7.8E-15 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS19470 343fedd3fabb4da9ecdbb4fb5756634d 450 Gene3D G3DSA:3.90.350.10 270 407 2.1E-6 T 28-03-2018 IPR014736 Transposase, Tn5-like, core MKLM6_RS13365 343fedd3fabb4da9ecdbb4fb5756634d 450 Pfam PF01609 Transposase DDE domain 274 441 3.7E-21 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS13365 343fedd3fabb4da9ecdbb4fb5756634d 450 Pfam PF05598 Transposase domain (DUF772) 52 121 7.8E-15 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS13365 343fedd3fabb4da9ecdbb4fb5756634d 450 Gene3D G3DSA:3.90.350.10 270 407 2.1E-6 T 28-03-2018 IPR014736 Transposase, Tn5-like, core MKLM6_RS07460 ac1101062b17bc821f56eb121bfdc8c4 208 Gene3D G3DSA:3.40.50.850 1 208 2.2E-44 T 28-03-2018 MKLM6_RS07460 ac1101062b17bc821f56eb121bfdc8c4 208 SUPERFAMILY SSF52499 4 203 2.22E-54 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 MKLM6_RS07460 ac1101062b17bc821f56eb121bfdc8c4 208 Pfam PF00857 Isochorismatase family 13 165 3.5E-22 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 MKLM6_RS11490 4b518510bce544b2dbe40c8c3dfdc3f1 570 Gene3D G3DSA:2.60.40.420 165 369 9.0E-37 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS11490 4b518510bce544b2dbe40c8c3dfdc3f1 570 SUPERFAMILY SSF49503 164 371 5.73E-51 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS11490 4b518510bce544b2dbe40c8c3dfdc3f1 570 SUPERFAMILY SSF49503 42 176 1.66E-35 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS11490 4b518510bce544b2dbe40c8c3dfdc3f1 570 Pfam PF00394 Multicopper oxidase 168 338 2.8E-26 T 28-03-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 MKLM6_RS11490 4b518510bce544b2dbe40c8c3dfdc3f1 570 SUPERFAMILY SSF49503 434 564 2.72E-33 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS11490 4b518510bce544b2dbe40c8c3dfdc3f1 570 ProSitePatterns PS00079 Multicopper oxidases signature 1. 542 562 - T 28-03-2018 IPR033138 Multicopper oxidases, conserved site MKLM6_RS11490 4b518510bce544b2dbe40c8c3dfdc3f1 570 ProSitePatterns PS00080 Multicopper oxidases signature 2. 547 558 - T 28-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 MKLM6_RS11490 4b518510bce544b2dbe40c8c3dfdc3f1 570 Gene3D G3DSA:2.60.40.420 370 565 2.4E-42 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS11490 4b518510bce544b2dbe40c8c3dfdc3f1 570 Pfam PF07731 Multicopper oxidase 450 565 3.2E-25 T 28-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 MKLM6_RS11490 4b518510bce544b2dbe40c8c3dfdc3f1 570 Pfam PF07732 Multicopper oxidase 50 160 3.4E-37 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 MKLM6_RS11490 4b518510bce544b2dbe40c8c3dfdc3f1 570 Gene3D G3DSA:2.60.40.420 32 164 3.8E-29 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS11490 4b518510bce544b2dbe40c8c3dfdc3f1 570 TIGRFAM TIGR01480 copper_res_A: copper-resistance protein, CopA family 41 564 2.0E-197 T 28-03-2018 IPR006376 Copper-resistance protein CopA GO:0005507|GO:0042597 MKLM6_RS18665 310bf0a59dde24089f6f15beb4d9c492 171 SUPERFAMILY SSF88659 96 168 9.91E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS18665 310bf0a59dde24089f6f15beb4d9c492 171 Gene3D G3DSA:1.10.10.10 74 168 1.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS18665 310bf0a59dde24089f6f15beb4d9c492 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 163 8.6E-29 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS18665 310bf0a59dde24089f6f15beb4d9c492 171 Pfam PF04542 Sigma-70 region 2 14 80 3.8E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS18665 310bf0a59dde24089f6f15beb4d9c492 171 SUPERFAMILY SSF88946 11 97 2.51E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS18665 310bf0a59dde24089f6f15beb4d9c492 171 Pfam PF08281 Sigma-70, region 4 110 162 4.4E-16 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS18665 310bf0a59dde24089f6f15beb4d9c492 171 Gene3D G3DSA:1.10.1740.10 2 73 3.8E-15 T 28-03-2018 MKLM6_RS02195 4143de516d7ba71cf9e780f34cef1490 108 PRINTS PR00421 Thioredoxin family signature 72 83 5.8E-10 T 28-03-2018 MKLM6_RS02195 4143de516d7ba71cf9e780f34cef1490 108 PRINTS PR00421 Thioredoxin family signature 32 41 5.8E-10 T 28-03-2018 MKLM6_RS02195 4143de516d7ba71cf9e780f34cef1490 108 PRINTS PR00421 Thioredoxin family signature 24 32 5.8E-10 T 28-03-2018 MKLM6_RS02195 4143de516d7ba71cf9e780f34cef1490 108 Gene3D G3DSA:3.40.30.10 1 108 3.5E-36 T 28-03-2018 MKLM6_RS02195 4143de516d7ba71cf9e780f34cef1490 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MKLM6_RS02195 4143de516d7ba71cf9e780f34cef1490 108 SUPERFAMILY SSF52833 5 108 1.26E-39 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS02195 4143de516d7ba71cf9e780f34cef1490 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 107 7.6E-39 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MKLM6_RS02195 4143de516d7ba71cf9e780f34cef1490 108 PIRSF PIRSF000077 2 108 2.1E-45 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MKLM6_RS02195 4143de516d7ba71cf9e780f34cef1490 108 Pfam PF00085 Thioredoxin 5 106 9.0E-35 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 MKLM6_RS14365 9f5444c48a252602442d4fa39badc2df 554 Gene3D G3DSA:2.160.20.10 199 551 2.0E-34 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS14365 9f5444c48a252602442d4fa39badc2df 554 Gene3D G3DSA:1.10.287.500 14 198 1.1E-7 T 28-03-2018 MKLM6_RS14365 9f5444c48a252602442d4fa39badc2df 554 SUPERFAMILY SSF58104 7 110 1.44E-5 T 28-03-2018 MKLM6_RS14365 9f5444c48a252602442d4fa39badc2df 554 SUPERFAMILY SSF51126 180 550 6.44E-30 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS06110 98816e9e4e4ec78cf3516a12b6e04f3e 1303 Gene3D G3DSA:3.30.465.10 249 436 1.2E-23 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MKLM6_RS06110 98816e9e4e4ec78cf3516a12b6e04f3e 1303 Pfam PF13183 4Fe-4S dicluster domain 834 913 2.7E-6 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MKLM6_RS06110 98816e9e4e4ec78cf3516a12b6e04f3e 1303 SUPERFAMILY SSF56176 149 414 1.96E-52 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MKLM6_RS06110 98816e9e4e4ec78cf3516a12b6e04f3e 1303 Pfam PF12447 Protein of unknown function (DUF3683) 16 135 5.2E-49 T 28-03-2018 IPR022153 Protein of unknown function DUF3683 MKLM6_RS06110 98816e9e4e4ec78cf3516a12b6e04f3e 1303 Pfam PF11880 Domain of unknown function (DUF3400) 1258 1303 9.7E-20 T 28-03-2018 IPR021817 Protein of unknown function DUF3400 MKLM6_RS06110 98816e9e4e4ec78cf3516a12b6e04f3e 1303 SUPERFAMILY SSF46548 820 929 1.96E-12 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MKLM6_RS06110 98816e9e4e4ec78cf3516a12b6e04f3e 1303 Gene3D G3DSA:3.30.43.10 129 237 2.3E-14 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 MKLM6_RS06110 98816e9e4e4ec78cf3516a12b6e04f3e 1303 Pfam PF02754 Cysteine-rich domain 1044 1133 7.3E-7 T 28-03-2018 IPR004017 Cysteine-rich domain MKLM6_RS06110 98816e9e4e4ec78cf3516a12b6e04f3e 1303 Pfam PF02754 Cysteine-rich domain 1169 1255 3.0E-4 T 28-03-2018 IPR004017 Cysteine-rich domain MKLM6_RS06110 98816e9e4e4ec78cf3516a12b6e04f3e 1303 SUPERFAMILY SSF55103 676 801 8.69E-41 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MKLM6_RS06110 98816e9e4e4ec78cf3516a12b6e04f3e 1303 SUPERFAMILY SSF55103 419 550 8.69E-41 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MKLM6_RS06110 98816e9e4e4ec78cf3516a12b6e04f3e 1303 Gene3D G3DSA:1.10.1060.10 766 935 2.0E-12 T 28-03-2018 MKLM6_RS06110 98816e9e4e4ec78cf3516a12b6e04f3e 1303 Pfam PF01565 FAD binding domain 185 331 9.4E-24 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MKLM6_RS06110 98816e9e4e4ec78cf3516a12b6e04f3e 1303 Pfam PF02913 FAD linked oxidases, C-terminal domain 710 798 1.1E-17 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 MKLM6_RS06110 98816e9e4e4ec78cf3516a12b6e04f3e 1303 Pfam PF02913 FAD linked oxidases, C-terminal domain 451 567 1.7E-5 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 MKLM6_RS20515 9e0b0bf75123cca1067e6f8b1462a22a 456 Gene3D G3DSA:3.90.190.20 316 450 2.3E-41 T 28-03-2018 MKLM6_RS20515 9e0b0bf75123cca1067e6f8b1462a22a 456 Gene3D G3DSA:3.40.50.720 2 111 2.0E-10 T 28-03-2018 MKLM6_RS20515 9e0b0bf75123cca1067e6f8b1462a22a 456 Gene3D G3DSA:3.40.1190.10 112 315 6.1E-64 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MKLM6_RS20515 9e0b0bf75123cca1067e6f8b1462a22a 456 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 21 453 34.532 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS20515 9e0b0bf75123cca1067e6f8b1462a22a 456 SUPERFAMILY SSF51984 19 110 1.14E-8 T 28-03-2018 MKLM6_RS20515 9e0b0bf75123cca1067e6f8b1462a22a 456 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 23 450 1.9E-129 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS20515 9e0b0bf75123cca1067e6f8b1462a22a 456 SUPERFAMILY SSF53623 113 313 1.44E-58 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MKLM6_RS20515 9e0b0bf75123cca1067e6f8b1462a22a 456 SUPERFAMILY SSF53244 315 453 9.16E-44 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MKLM6_RS20515 9e0b0bf75123cca1067e6f8b1462a22a 456 Pfam PF08245 Mur ligase middle domain 127 295 3.0E-32 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MKLM6_RS20515 9e0b0bf75123cca1067e6f8b1462a22a 456 Pfam PF02875 Mur ligase family, glutamate ligase domain 317 384 1.5E-7 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MKLM6_RS03215 2590f297eae4c9cd2dd20352557d9c5c 87 Pfam PF01649 Ribosomal protein S20 2 83 4.7E-28 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS03215 2590f297eae4c9cd2dd20352557d9c5c 87 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 87 1.0E-22 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS03215 2590f297eae4c9cd2dd20352557d9c5c 87 Gene3D G3DSA:1.20.58.110 1 87 8.7E-31 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS03215 2590f297eae4c9cd2dd20352557d9c5c 87 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 18.292 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS03215 2590f297eae4c9cd2dd20352557d9c5c 87 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 85 4.9E-28 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS03215 2590f297eae4c9cd2dd20352557d9c5c 87 SUPERFAMILY SSF46992 3 86 1.44E-30 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS16540 abaa4dd85d76bf8cc015e2e823b9d4ab 69 Gene3D G3DSA:3.30.70.100 1 69 5.1E-20 T 28-03-2018 MKLM6_RS16540 abaa4dd85d76bf8cc015e2e823b9d4ab 69 SUPERFAMILY SSF55008 5 69 5.89E-18 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MKLM6_RS16540 abaa4dd85d76bf8cc015e2e823b9d4ab 69 Pfam PF00403 Heavy-metal-associated domain 6 67 1.4E-14 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MKLM6_RS19735 a8daf30e19eddbf391cb275a500c9ca4 219 Gene3D G3DSA:1.10.10.10 134 217 1.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS19735 a8daf30e19eddbf391cb275a500c9ca4 219 SMART SM00421 155 212 1.5E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS19735 a8daf30e19eddbf391cb275a500c9ca4 219 Gene3D G3DSA:3.40.50.2300 13 133 7.6E-19 T 28-03-2018 MKLM6_RS19735 a8daf30e19eddbf391cb275a500c9ca4 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 210 1.4E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS19735 a8daf30e19eddbf391cb275a500c9ca4 219 SUPERFAMILY SSF52172 15 139 2.99E-17 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS19735 a8daf30e19eddbf391cb275a500c9ca4 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 1.9E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS19735 a8daf30e19eddbf391cb275a500c9ca4 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 1.9E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS19735 a8daf30e19eddbf391cb275a500c9ca4 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 1.9E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS19735 a8daf30e19eddbf391cb275a500c9ca4 219 Pfam PF00072 Response regulator receiver domain 15 125 6.6E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS19735 a8daf30e19eddbf391cb275a500c9ca4 219 SMART SM00448 14 125 6.6E-9 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS19735 a8daf30e19eddbf391cb275a500c9ca4 219 SUPERFAMILY SSF46894 147 215 7.82E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MKLM6_RS11690 1a5def00519d688eb898850dd2c2c7fb 375 Gene3D G3DSA:3.40.50.300 1 206 1.0E-10 T 28-03-2018 MKLM6_RS11690 1a5def00519d688eb898850dd2c2c7fb 375 Pfam PF05707 Zonular occludens toxin (Zot) 7 204 3.6E-20 T 28-03-2018 IPR008900 Zona occludens toxin MKLM6_RS08080 a9e73bb5db2474fb3dfe0648ad9696d5 926 SUPERFAMILY SSF52540 63 252 5.6E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS08080 a9e73bb5db2474fb3dfe0648ad9696d5 926 SUPERFAMILY SSF52540 13 31 5.6E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS08080 a9e73bb5db2474fb3dfe0648ad9696d5 926 Pfam PF04851 Type III restriction enzyme, res subunit 13 235 9.2E-29 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MKLM6_RS08080 a9e73bb5db2474fb3dfe0648ad9696d5 926 Gene3D G3DSA:3.40.50.300 284 463 1.6E-4 T 28-03-2018 MKLM6_RS08080 a9e73bb5db2474fb3dfe0648ad9696d5 926 Gene3D G3DSA:3.40.91.30 799 894 4.3E-5 T 28-03-2018 MKLM6_RS08080 a9e73bb5db2474fb3dfe0648ad9696d5 926 SUPERFAMILY SSF52540 202 426 2.86E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS08080 a9e73bb5db2474fb3dfe0648ad9696d5 926 Gene3D G3DSA:3.40.50.300 10 241 9.2E-9 T 28-03-2018 MKLM6_RS17540 0b721aa21565d121fb6b7e2f1309fa05 354 PIRSF PIRSF005508 2 352 1.1E-135 T 28-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 MKLM6_RS17540 0b721aa21565d121fb6b7e2f1309fa05 354 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 11 341 8.3E-138 T 28-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 MKLM6_RS17540 0b721aa21565d121fb6b7e2f1309fa05 354 Pfam PF01758 Sodium Bile acid symporter family 59 253 1.4E-66 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 MKLM6_RS10440 04236cdd2497c837273cd59b69d9a028 618 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 194 339 3.8E-10 T 28-03-2018 MKLM6_RS10440 04236cdd2497c837273cd59b69d9a028 618 Pfam PF10102 Domain of unknown function (DUF2341) 71 154 2.5E-11 T 28-03-2018 IPR018765 Domain of unknown function DUF2341 MKLM6_RS10440 04236cdd2497c837273cd59b69d9a028 618 SUPERFAMILY SSF49899 136 346 1.7E-20 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain MKLM6_RS10440 04236cdd2497c837273cd59b69d9a028 618 Pfam PF01618 MotA/TolQ/ExbB proton channel family 475 591 7.3E-28 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 MKLM6_RS10440 04236cdd2497c837273cd59b69d9a028 618 Gene3D G3DSA:2.60.120.200 138 355 2.2E-23 T 28-03-2018 MKLM6_RS06635 f29877c32a9efc80cee43f51fd1d8b53 386 TIGRFAM TIGR01869 casC_Cse4: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI 4 348 1.2E-96 T 28-03-2018 IPR010148 CRISPR-associated protein, CT1975 MKLM6_RS06635 f29877c32a9efc80cee43f51fd1d8b53 386 Pfam PF09344 CT1975-like protein 6 364 1.3E-99 T 28-03-2018 IPR010148 CRISPR-associated protein, CT1975 MKLM6_RS02840 8fc3a3fe835a84b01c01a1fc5005387f 369 Gene3D G3DSA:3.40.50.2000 169 369 4.9E-43 T 28-03-2018 MKLM6_RS02840 8fc3a3fe835a84b01c01a1fc5005387f 369 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 94 302 1.7E-32 T 28-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 MKLM6_RS02840 8fc3a3fe835a84b01c01a1fc5005387f 369 SUPERFAMILY SSF53756 19 367 1.32E-69 T 28-03-2018 MKLM6_RS02840 8fc3a3fe835a84b01c01a1fc5005387f 369 Gene3D G3DSA:3.40.50.2000 11 168 2.4E-26 T 28-03-2018 MKLM6_RS04660 d0a1a9b5359de9c4562f3609c82df214 559 Pfam PF01464 Transglycosylase SLT domain 391 503 6.7E-11 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 MKLM6_RS04660 d0a1a9b5359de9c4562f3609c82df214 559 SUPERFAMILY SSF49879 49 127 2.68E-21 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MKLM6_RS04660 d0a1a9b5359de9c4562f3609c82df214 559 Gene3D G3DSA:1.10.530.10 362 544 2.0E-18 T 28-03-2018 MKLM6_RS04660 d0a1a9b5359de9c4562f3609c82df214 559 SMART SM00240 51 101 5.3E-14 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MKLM6_RS04660 d0a1a9b5359de9c4562f3609c82df214 559 Gene3D G3DSA:2.60.200.20 36 305 3.0E-20 T 28-03-2018 MKLM6_RS04660 d0a1a9b5359de9c4562f3609c82df214 559 SUPERFAMILY SSF53955 371 540 1.69E-20 T 28-03-2018 IPR023346 Lysozyme-like domain MKLM6_RS04660 d0a1a9b5359de9c4562f3609c82df214 559 Pfam PF00498 FHA domain 53 115 7.6E-17 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MKLM6_RS08485 983677a7ea64c334e3424fadb88f5d13 491 Gene3D G3DSA:1.20.1250.20 287 484 3.6E-21 T 28-03-2018 MKLM6_RS08485 983677a7ea64c334e3424fadb88f5d13 491 TIGRFAM TIGR00886 2A0108: nitrite transporter 16 436 5.1E-106 T 28-03-2018 IPR004737 Nitrate transporter GO:0015112|GO:0015113|GO:0015706|GO:0015707|GO:0016021 MKLM6_RS08485 983677a7ea64c334e3424fadb88f5d13 491 SUPERFAMILY SSF103473 274 469 9.16E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain MKLM6_RS08485 983677a7ea64c334e3424fadb88f5d13 491 SUPERFAMILY SSF103473 13 203 9.16E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain MKLM6_RS08485 983677a7ea64c334e3424fadb88f5d13 491 Gene3D G3DSA:1.20.1250.20 12 208 1.3E-27 T 28-03-2018 MKLM6_RS08485 983677a7ea64c334e3424fadb88f5d13 491 Pfam PF07690 Major Facilitator Superfamily 22 437 1.2E-36 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MKLM6_RS06590 361cb82676b8c69d82cda87668fc3229 820 Gene3D G3DSA:3.40.50.300 168 505 4.0E-22 T 28-03-2018 MKLM6_RS06590 361cb82676b8c69d82cda87668fc3229 820 SMART SM00487 260 485 5.0E-12 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MKLM6_RS06590 361cb82676b8c69d82cda87668fc3229 820 Pfam PF00270 DEAD/DEAH box helicase 274 461 4.2E-10 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MKLM6_RS06590 361cb82676b8c69d82cda87668fc3229 820 SUPERFAMILY SSF52540 278 329 1.64E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS06590 361cb82676b8c69d82cda87668fc3229 820 SUPERFAMILY SSF52540 503 644 1.64E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS06590 361cb82676b8c69d82cda87668fc3229 820 SUPERFAMILY SSF52540 367 459 1.64E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS06590 361cb82676b8c69d82cda87668fc3229 820 Gene3D G3DSA:3.40.50.300 519 654 7.4E-12 T 28-03-2018 MKLM6_RS06590 361cb82676b8c69d82cda87668fc3229 820 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 281 690 7.9E-91 T 28-03-2018 IPR006474 Helicase Cas3, CRISPR-associated, core MKLM6_RS06590 361cb82676b8c69d82cda87668fc3229 820 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 27 212 2.4E-20 T 28-03-2018 IPR006483 CRISPR-associated Cas3-HD domain MKLM6_RS00855 c58ebd165b92b270b24bbb0fbc6a7897 359 Gene3D G3DSA:3.90.1150.10 248 353 5.4E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS00855 c58ebd165b92b270b24bbb0fbc6a7897 359 Gene3D G3DSA:3.40.640.10 55 247 2.5E-37 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS00855 c58ebd165b92b270b24bbb0fbc6a7897 359 SUPERFAMILY SSF53383 11 358 2.58E-75 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS00855 c58ebd165b92b270b24bbb0fbc6a7897 359 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 9 358 54.642 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MKLM6_RS00855 c58ebd165b92b270b24bbb0fbc6a7897 359 Pfam PF00155 Aminotransferase class I and II 27 354 2.0E-43 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MKLM6_RS00855 c58ebd165b92b270b24bbb0fbc6a7897 359 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 11 355 1.6E-94 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MKLM6_RS07555 b27d382c4623aa1d8e0dda3f5c9fbf15 440 Pfam PF02321 Outer membrane efflux protein 66 236 3.8E-19 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS07555 b27d382c4623aa1d8e0dda3f5c9fbf15 440 Pfam PF02321 Outer membrane efflux protein 260 434 1.1E-23 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS07555 b27d382c4623aa1d8e0dda3f5c9fbf15 440 SUPERFAMILY SSF56954 47 435 4.19E-63 T 28-03-2018 MKLM6_RS07555 b27d382c4623aa1d8e0dda3f5c9fbf15 440 SUPERFAMILY SSF56954 2 22 4.19E-63 T 28-03-2018 MKLM6_RS07555 b27d382c4623aa1d8e0dda3f5c9fbf15 440 Gene3D G3DSA:1.20.1600.10 29 440 6.9E-55 T 28-03-2018 MKLM6_RS08040 9aea78a513195056ec2c81c317765d90 968 SUPERFAMILY SSF52540 395 447 2.31E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS08040 9aea78a513195056ec2c81c317765d90 968 SUPERFAMILY SSF52540 476 592 2.31E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS08040 9aea78a513195056ec2c81c317765d90 968 SUPERFAMILY SSF52540 158 217 2.31E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS08040 9aea78a513195056ec2c81c317765d90 968 Pfam PF00271 Helicase conserved C-terminal domain 440 548 6.4E-19 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS08040 9aea78a513195056ec2c81c317765d90 968 Gene3D G3DSA:3.40.50.300 388 587 3.3E-28 T 28-03-2018 MKLM6_RS08040 9aea78a513195056ec2c81c317765d90 968 SMART SM00487 36 227 9.4E-23 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MKLM6_RS08040 9aea78a513195056ec2c81c317765d90 968 SUPERFAMILY SSF52540 32 233 2.15E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS08040 9aea78a513195056ec2c81c317765d90 968 Pfam PF00176 SNF2 family N-terminal domain 8 260 5.5E-31 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 MKLM6_RS08040 9aea78a513195056ec2c81c317765d90 968 SMART SM00490 468 548 1.1E-21 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS08040 9aea78a513195056ec2c81c317765d90 968 Gene3D G3DSA:1.20.1000.10 597 959 1.4E-15 T 28-03-2018 MKLM6_RS08040 9aea78a513195056ec2c81c317765d90 968 Gene3D G3DSA:3.40.50.10810 27 268 6.3E-37 T 28-03-2018 MKLM6_RS04070 1063171fc4a89671bf24d786799e17d4 455 Hamap MF_01498 DNA repair protein RadA [radA]. 22 453 41.701 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 MKLM6_RS04070 1063171fc4a89671bf24d786799e17d4 455 PRINTS PR01874 DNA repair protein radA signature 172 196 7.2E-86 T 28-03-2018 MKLM6_RS04070 1063171fc4a89671bf24d786799e17d4 455 PRINTS PR01874 DNA repair protein radA signature 320 343 7.2E-86 T 28-03-2018 MKLM6_RS04070 1063171fc4a89671bf24d786799e17d4 455 PRINTS PR01874 DNA repair protein radA signature 211 239 7.2E-86 T 28-03-2018 MKLM6_RS04070 1063171fc4a89671bf24d786799e17d4 455 PRINTS PR01874 DNA repair protein radA signature 11 35 7.2E-86 T 28-03-2018 MKLM6_RS04070 1063171fc4a89671bf24d786799e17d4 455 PRINTS PR01874 DNA repair protein radA signature 122 139 7.2E-86 T 28-03-2018 MKLM6_RS04070 1063171fc4a89671bf24d786799e17d4 455 PRINTS PR01874 DNA repair protein radA signature 246 272 7.2E-86 T 28-03-2018 MKLM6_RS04070 1063171fc4a89671bf24d786799e17d4 455 PRINTS PR01874 DNA repair protein radA signature 81 109 7.2E-86 T 28-03-2018 MKLM6_RS04070 1063171fc4a89671bf24d786799e17d4 455 Gene3D G3DSA:3.30.230.10 284 453 3.0E-28 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MKLM6_RS04070 1063171fc4a89671bf24d786799e17d4 455 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 449 1.4E-187 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 MKLM6_RS04070 1063171fc4a89671bf24d786799e17d4 455 Pfam PF13541 Subunit ChlI of Mg-chelatase 361 428 2.3E-8 T 28-03-2018 MKLM6_RS04070 1063171fc4a89671bf24d786799e17d4 455 Pfam PF13481 AAA domain 70 220 1.5E-19 T 28-03-2018 MKLM6_RS04070 1063171fc4a89671bf24d786799e17d4 455 SUPERFAMILY SSF52540 68 289 5.35E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS04070 1063171fc4a89671bf24d786799e17d4 455 SMART SM00382 89 242 9.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS04070 1063171fc4a89671bf24d786799e17d4 455 Gene3D G3DSA:3.40.50.300 70 282 1.1E-40 T 28-03-2018 MKLM6_RS04070 1063171fc4a89671bf24d786799e17d4 455 SUPERFAMILY SSF54211 291 452 1.02E-38 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS13075 b509c613dd4d5c5eff03f61168f162d5 267 Gene3D G3DSA:3.30.70.660 106 243 2.2E-35 T 28-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS13075 b509c613dd4d5c5eff03f61168f162d5 267 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 244 34.094 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS13075 b509c613dd4d5c5eff03f61168f162d5 267 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 3 238 6.9E-66 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS13075 b509c613dd4d5c5eff03f61168f162d5 267 Gene3D G3DSA:3.30.70.580 1 105 7.1E-34 T 28-03-2018 MKLM6_RS13075 b509c613dd4d5c5eff03f61168f162d5 267 PIRSF PIRSF001430 1 254 1.1E-77 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS13075 b509c613dd4d5c5eff03f61168f162d5 267 Pfam PF01416 tRNA pseudouridine synthase 9 103 1.3E-6 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS13075 b509c613dd4d5c5eff03f61168f162d5 267 Pfam PF01416 tRNA pseudouridine synthase 143 245 7.1E-29 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS13075 b509c613dd4d5c5eff03f61168f162d5 267 SUPERFAMILY SSF55120 1 251 7.48E-91 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS08450 a0e20fed7e2dc45c4cc4520afaf9c97d 386 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 151 383 2.1E-63 T 28-03-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria MKLM6_RS08450 a0e20fed7e2dc45c4cc4520afaf9c97d 386 Pfam PF02405 Permease MlaE 172 380 1.4E-68 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 MKLM6_RS02935 446b47dd0249f93b767f9e9584216df5 315 SUPERFAMILY SSF53474 4 294 4.92E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS02935 446b47dd0249f93b767f9e9584216df5 315 Pfam PF00561 alpha/beta hydrolase fold 38 294 1.5E-26 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS02935 446b47dd0249f93b767f9e9584216df5 315 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 37 45 7.5E-12 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MKLM6_RS02935 446b47dd0249f93b767f9e9584216df5 315 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 63 74 7.5E-12 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MKLM6_RS02935 446b47dd0249f93b767f9e9584216df5 315 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 106 120 7.5E-12 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MKLM6_RS02935 446b47dd0249f93b767f9e9584216df5 315 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 9 310 1.9E-94 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 MKLM6_RS02935 446b47dd0249f93b767f9e9584216df5 315 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 2.9E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS02935 446b47dd0249f93b767f9e9584216df5 315 PRINTS PR00111 Alpha/beta hydrolase fold signature 60 75 2.9E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS02935 446b47dd0249f93b767f9e9584216df5 315 PRINTS PR00111 Alpha/beta hydrolase fold signature 120 133 2.9E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS02935 446b47dd0249f93b767f9e9584216df5 315 PIRSF PIRSF006431 1 314 6.9E-113 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 MKLM6_RS02935 446b47dd0249f93b767f9e9584216df5 315 Gene3D G3DSA:3.40.50.1820 1 312 1.1E-56 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS11240 9bc9464e9b7d4e0ded57cf38eb935754 442 SUPERFAMILY SSF53756 106 367 6.28E-24 T 28-03-2018 MKLM6_RS11240 9bc9464e9b7d4e0ded57cf38eb935754 442 Gene3D G3DSA:3.40.50.2000 157 366 2.3E-29 T 28-03-2018 MKLM6_RS11240 9bc9464e9b7d4e0ded57cf38eb935754 442 Pfam PF00534 Glycosyl transferases group 1 242 364 1.4E-11 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 MKLM6_RS19230 333d3d3c967f111bbe8880d3dccced0e 343 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 11 343 8.5E-140 T 28-03-2018 IPR011854 Hydrogenase expression/formation protein HypE MKLM6_RS19230 333d3d3c967f111bbe8880d3dccced0e 343 Pfam PF00586 AIR synthase related protein, N-terminal domain 56 156 7.7E-17 T 28-03-2018 IPR016188 PurM-like, N-terminal domain MKLM6_RS19230 333d3d3c967f111bbe8880d3dccced0e 343 Gene3D G3DSA:3.30.1330.10 8 159 8.3E-28 T 28-03-2018 IPR016188 PurM-like, N-terminal domain MKLM6_RS19230 333d3d3c967f111bbe8880d3dccced0e 343 Gene3D G3DSA:3.90.650.10 162 331 2.2E-38 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MKLM6_RS19230 333d3d3c967f111bbe8880d3dccced0e 343 SUPERFAMILY SSF55326 11 160 5.98E-34 T 28-03-2018 IPR016188 PurM-like, N-terminal domain MKLM6_RS19230 333d3d3c967f111bbe8880d3dccced0e 343 PIRSF PIRSF005644 7 343 4.1E-125 T 28-03-2018 IPR011854 Hydrogenase expression/formation protein HypE MKLM6_RS19230 333d3d3c967f111bbe8880d3dccced0e 343 SUPERFAMILY SSF56042 162 339 3.74E-44 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MKLM6_RS19230 333d3d3c967f111bbe8880d3dccced0e 343 Pfam PF02769 AIR synthase related protein, C-terminal domain 169 320 2.1E-30 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MKLM6_RS01495 13975bba24663992d39dbbb547d8b15f 410 Pfam PF03486 HI0933-like protein 8 402 1.1E-114 T 28-03-2018 MKLM6_RS01495 13975bba24663992d39dbbb547d8b15f 410 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 9 401 2.8E-91 T 28-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like MKLM6_RS01495 13975bba24663992d39dbbb547d8b15f 410 TIGRFAM TIGR03862 flavo_PP4765: flavoprotein, TIGR03862 family 30 408 5.2E-164 T 28-03-2018 IPR022460 Conserved hyptotheical protein CHP03862, flavoprotein, PP4765 MKLM6_RS01495 13975bba24663992d39dbbb547d8b15f 410 Gene3D G3DSA:3.50.50.60 7 404 5.7E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS01495 13975bba24663992d39dbbb547d8b15f 410 SUPERFAMILY SSF51905 348 405 4.47E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS01495 13975bba24663992d39dbbb547d8b15f 410 SUPERFAMILY SSF51905 8 194 4.47E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS01495 13975bba24663992d39dbbb547d8b15f 410 SUPERFAMILY SSF160996 195 347 6.15E-16 T 28-03-2018 MKLM6_RS18885 3fc0a0636ecd36b9485af98342d5a8de 200 Gene3D G3DSA:3.90.1570.10 7 198 2.3E-43 T 28-03-2018 MKLM6_RS18885 3fc0a0636ecd36b9485af98342d5a8de 200 Pfam PF05685 Putative restriction endonuclease 20 194 6.4E-30 T 28-03-2018 IPR008538 Domain of unknown function DUF820 MKLM6_RS18885 3fc0a0636ecd36b9485af98342d5a8de 200 SUPERFAMILY SSF52980 13 198 1.93E-35 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MKLM6_RS17520 d6afc315657345acbaedd527d0adbb84 520 SMART SM00098 57 517 3.2E-160 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MKLM6_RS17520 d6afc315657345acbaedd527d0adbb84 520 Gene3D G3DSA:3.40.720.10 15 520 4.5E-150 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MKLM6_RS17520 d6afc315657345acbaedd527d0adbb84 520 PRINTS PR00113 Alkaline phosphatase signature 161 181 9.9E-47 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MKLM6_RS17520 d6afc315657345acbaedd527d0adbb84 520 PRINTS PR00113 Alkaline phosphatase signature 56 76 9.9E-47 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MKLM6_RS17520 d6afc315657345acbaedd527d0adbb84 520 PRINTS PR00113 Alkaline phosphatase signature 310 339 9.9E-47 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MKLM6_RS17520 d6afc315657345acbaedd527d0adbb84 520 PRINTS PR00113 Alkaline phosphatase signature 220 230 9.9E-47 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MKLM6_RS17520 d6afc315657345acbaedd527d0adbb84 520 PRINTS PR00113 Alkaline phosphatase signature 112 127 9.9E-47 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MKLM6_RS17520 d6afc315657345acbaedd527d0adbb84 520 SUPERFAMILY SSF53649 33 517 8.11E-146 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MKLM6_RS17520 d6afc315657345acbaedd527d0adbb84 520 Pfam PF00245 Alkaline phosphatase 56 515 6.6E-122 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MKLM6_RS02605 085371a13a3f90c755eb4d84d4fbb01a 161 Pfam PF04116 Fatty acid hydroxylase superfamily 9 150 2.6E-7 T 28-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 MKLM6_RS00370 44b24a969e1a97b241e0c475f6cd2250 355 SUPERFAMILY SSF51395 1 353 3.42E-119 T 28-03-2018 MKLM6_RS00370 44b24a969e1a97b241e0c475f6cd2250 355 Gene3D G3DSA:3.20.20.70 3 355 2.3E-120 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS00370 44b24a969e1a97b241e0c475f6cd2250 355 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 327 9.4E-78 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MKLM6_RS08845 d222401ab5c5de1e93ad79269e31ff16 739 SUPERFAMILY SSF46626 380 461 6.3E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS08845 d222401ab5c5de1e93ad79269e31ff16 739 SUPERFAMILY SSF46626 595 684 6.3E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS08845 d222401ab5c5de1e93ad79269e31ff16 739 SUPERFAMILY SSF46626 232 279 3.2E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS08845 d222401ab5c5de1e93ad79269e31ff16 739 SUPERFAMILY SSF46626 174 194 3.2E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS08845 d222401ab5c5de1e93ad79269e31ff16 739 SUPERFAMILY SSF46626 35 81 3.2E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS08845 d222401ab5c5de1e93ad79269e31ff16 739 Gene3D G3DSA:1.10.760.10 354 690 4.4E-30 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS08845 d222401ab5c5de1e93ad79269e31ff16 739 Gene3D G3DSA:1.10.760.10 31 353 4.3E-28 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS08845 d222401ab5c5de1e93ad79269e31ff16 739 Pfam PF03150 Di-haem cytochrome c peroxidase 37 360 6.9E-21 T 28-03-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 MKLM6_RS09830 c2c1398a5d5f253890408318fcf13ee3 704 Gene3D G3DSA:3.90.70.10 15 145 2.4E-37 T 28-03-2018 MKLM6_RS09830 c2c1398a5d5f253890408318fcf13ee3 704 Gene3D G3DSA:3.40.50.300 474 703 1.6E-58 T 28-03-2018 MKLM6_RS09830 c2c1398a5d5f253890408318fcf13ee3 704 Pfam PF00005 ABC transporter 500 648 2.5E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS09830 c2c1398a5d5f253890408318fcf13ee3 704 Pfam PF03412 Peptidase C39 family 13 141 4.7E-34 T 28-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 MKLM6_RS09830 c2c1398a5d5f253890408318fcf13ee3 704 SUPERFAMILY SSF52540 480 689 1.86E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS09830 c2c1398a5d5f253890408318fcf13ee3 704 SMART SM00382 508 692 5.3E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS09830 c2c1398a5d5f253890408318fcf13ee3 704 SUPERFAMILY SSF90123 156 461 5.23E-54 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MKLM6_RS09830 c2c1398a5d5f253890408318fcf13ee3 704 Pfam PF00664 ABC transporter transmembrane region 171 435 2.1E-34 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MKLM6_RS09830 c2c1398a5d5f253890408318fcf13ee3 704 ProSitePatterns PS00211 ABC transporters family signature. 620 634 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS09830 c2c1398a5d5f253890408318fcf13ee3 704 Gene3D G3DSA:1.20.1560.10 146 469 1.3E-37 T 28-03-2018 MKLM6_RS09595 89519813f725f973351814a2af248fe8 523 SUPERFAMILY SSF51905 9 247 1.14E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS09595 89519813f725f973351814a2af248fe8 523 Pfam PF06100 MCRA family 5 492 1.0E-203 T 28-03-2018 IPR010354 Oleate hydratase GO:0006631|GO:0050151|GO:0071949 MKLM6_RS09595 89519813f725f973351814a2af248fe8 523 Gene3D G3DSA:3.50.50.60 9 318 2.1E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS17345 21b9c61afca957b5389c7adc06009f5a 606 Pfam PF11739 Dicarboxylate transport 401 586 1.2E-40 T 28-03-2018 IPR021730 Dicarboxylate transport MKLM6_RS03995 4d654e9c49492bf9ac76df83744d23f9 286 TIGRFAM TIGR03871 ABC_peri_MoxJ_2: quinoprotein dehydrogenase-associated probable ABC transporter substrate-binding protein 29 273 7.2E-76 T 28-03-2018 IPR022448 Quinoprotein dehydrogenase-associated MKLM6_RS03995 4d654e9c49492bf9ac76df83744d23f9 286 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 30 264 4.8E-9 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MKLM6_RS03995 4d654e9c49492bf9ac76df83744d23f9 286 SMART SM00062 28 267 5.0E-12 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MKLM6_RS03995 4d654e9c49492bf9ac76df83744d23f9 286 Gene3D G3DSA:3.40.190.10 126 228 5.5E-7 T 28-03-2018 MKLM6_RS03995 4d654e9c49492bf9ac76df83744d23f9 286 SUPERFAMILY SSF53850 21 267 1.0E-17 T 28-03-2018 MKLM6_RS03995 4d654e9c49492bf9ac76df83744d23f9 286 Gene3D G3DSA:3.40.190.10 23 125 8.1E-6 T 28-03-2018 MKLM6_RS03380 a5fb72d5cb0b294b73547cb51900532b 178 SUPERFAMILY SSF50475 9 159 6.25E-35 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MKLM6_RS03380 a5fb72d5cb0b294b73547cb51900532b 178 PIRSF PIRSF004633 1 173 1.4E-54 T 28-03-2018 IPR014419 Heme utilization protein with pyridoxamine 5'-phosphate domain MKLM6_RS03380 a5fb72d5cb0b294b73547cb51900532b 178 Gene3D G3DSA:2.30.110.10 5 171 1.2E-31 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MKLM6_RS03380 a5fb72d5cb0b294b73547cb51900532b 178 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 14 101 2.7E-17 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MKLM6_RS01685 9657e70456a46309f49cec54415f7ea3 689 Pfam PF05746 DALR anticodon binding domain 583 676 5.3E-6 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MKLM6_RS01685 9657e70456a46309f49cec54415f7ea3 689 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 4 688 1.3E-232 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MKLM6_RS01685 9657e70456a46309f49cec54415f7ea3 689 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 4 687 24.899 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MKLM6_RS01685 9657e70456a46309f49cec54415f7ea3 689 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 7 552 7.0E-204 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MKLM6_RS01685 9657e70456a46309f49cec54415f7ea3 689 Gene3D G3DSA:1.10.3210.10 340 519 0.0022 T 28-03-2018 MKLM6_RS01685 9657e70456a46309f49cec54415f7ea3 689 SUPERFAMILY SSF109604 346 491 2.51E-13 T 28-03-2018 MKLM6_RS01685 9657e70456a46309f49cec54415f7ea3 689 Gene3D G3DSA:1.10.730.10 577 681 1.7E-9 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS01685 9657e70456a46309f49cec54415f7ea3 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 395 414 4.5E-30 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MKLM6_RS01685 9657e70456a46309f49cec54415f7ea3 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 8 21 4.5E-30 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MKLM6_RS01685 9657e70456a46309f49cec54415f7ea3 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 247 262 4.5E-30 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MKLM6_RS01685 9657e70456a46309f49cec54415f7ea3 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 319 335 4.5E-30 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MKLM6_RS01685 9657e70456a46309f49cec54415f7ea3 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 51 63 4.5E-30 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 SUPERFAMILY SSF82714 193 276 1.31E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 SUPERFAMILY SSF82714 711 794 9.16E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 SUPERFAMILY SSF82693 146 192 9.03E-23 T 28-03-2018 MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 SUPERFAMILY SSF82693 278 334 9.03E-23 T 28-03-2018 MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 Gene3D G3DSA:1.20.1640.10 278 502 9.6E-46 T 28-03-2018 MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 Gene3D G3DSA:1.20.1640.10 810 1019 5.3E-33 T 28-03-2018 MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 Gene3D G3DSA:3.30.2090.10 709 800 1.4E-20 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 Gene3D G3DSA:3.30.2090.10 191 277 1.8E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 SUPERFAMILY SSF82866 300 501 1.26E-46 T 28-03-2018 MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 PRINTS PR00702 Acriflavin resistance protein family signature 448 471 3.7E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 PRINTS PR00702 Acriflavin resistance protein family signature 473 496 3.7E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 PRINTS PR00702 Acriflavin resistance protein family signature 48 66 3.7E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 PRINTS PR00702 Acriflavin resistance protein family signature 367 388 3.7E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 PRINTS PR00702 Acriflavin resistance protein family signature 548 565 3.7E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 PRINTS PR00702 Acriflavin resistance protein family signature 20 44 3.7E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 PRINTS PR00702 Acriflavin resistance protein family signature 395 419 3.7E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 PRINTS PR00702 Acriflavin resistance protein family signature 615 629 3.7E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 PRINTS PR00702 Acriflavin resistance protein family signature 340 363 3.7E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 SUPERFAMILY SSF82866 821 1017 1.44E-42 T 28-03-2018 MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 SUPERFAMILY SSF82693 797 840 7.15E-11 T 28-03-2018 MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 SUPERFAMILY SSF82693 670 710 7.15E-11 T 28-03-2018 MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 Gene3D G3DSA:3.30.70.1430 564 661 4.0E-11 T 28-03-2018 MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 SUPERFAMILY SSF82693 50 141 2.33E-24 T 28-03-2018 MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 Gene3D G3DSA:3.30.70.1430 50 152 6.8E-25 T 28-03-2018 MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 Pfam PF00873 AcrB/AcrD/AcrF family 14 1017 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS09135 aeaec5e46c57d7c339385b19a22016af 1043 SUPERFAMILY SSF82693 561 657 2.09E-13 T 28-03-2018 MKLM6_RS20795 ba6946a84b64cef4ed85b13b996d6276 376 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 4 347 2.0E-113 T 28-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 MKLM6_RS20795 ba6946a84b64cef4ed85b13b996d6276 376 Gene3D G3DSA:3.20.20.70 2 297 6.0E-48 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS20795 ba6946a84b64cef4ed85b13b996d6276 376 Gene3D G3DSA:1.10.10.10 308 374 0.0081 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS20795 ba6946a84b64cef4ed85b13b996d6276 376 SUPERFAMILY SSF102114 3 375 7.46E-106 T 28-03-2018 MKLM6_RS20795 ba6946a84b64cef4ed85b13b996d6276 376 Pfam PF04055 Radical SAM superfamily 8 175 1.6E-19 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS20795 ba6946a84b64cef4ed85b13b996d6276 376 SMART SM00729 3 218 1.1E-46 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MKLM6_RS20795 ba6946a84b64cef4ed85b13b996d6276 376 Pfam PF06969 HemN C-terminal domain 307 364 7.6E-13 T 28-03-2018 IPR010723 HemN, C-terminal MKLM6_RS10630 dd7c75dfa3c438ae8490a7fe5d5b477f 540 Gene3D G3DSA:3.50.50.60 2 257 6.5E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS10630 dd7c75dfa3c438ae8490a7fe5d5b477f 540 Gene3D G3DSA:3.50.50.60 338 407 3.6E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS10630 dd7c75dfa3c438ae8490a7fe5d5b477f 540 SUPERFAMILY SSF46977 424 525 5.36E-31 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MKLM6_RS10630 dd7c75dfa3c438ae8490a7fe5d5b477f 540 Pfam PF00890 FAD binding domain 8 390 5.7E-102 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MKLM6_RS10630 dd7c75dfa3c438ae8490a7fe5d5b477f 540 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 8 518 1.6E-191 T 28-03-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 MKLM6_RS10630 dd7c75dfa3c438ae8490a7fe5d5b477f 540 SUPERFAMILY SSF56425 236 351 1.12E-43 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MKLM6_RS10630 dd7c75dfa3c438ae8490a7fe5d5b477f 540 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 9.7E-10 T 28-03-2018 MKLM6_RS10630 dd7c75dfa3c438ae8490a7fe5d5b477f 540 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 353 375 9.7E-10 T 28-03-2018 MKLM6_RS10630 dd7c75dfa3c438ae8490a7fe5d5b477f 540 PIRSF PIRSF000171 3 538 8.7E-38 T 28-03-2018 MKLM6_RS10630 dd7c75dfa3c438ae8490a7fe5d5b477f 540 Gene3D G3DSA:3.90.700.10 258 337 7.4E-38 T 28-03-2018 MKLM6_RS10630 dd7c75dfa3c438ae8490a7fe5d5b477f 540 Pfam PF02910 Fumarate reductase flavoprotein C-term 439 531 1.4E-15 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MKLM6_RS10630 dd7c75dfa3c438ae8490a7fe5d5b477f 540 SUPERFAMILY SSF51905 354 446 6.05E-70 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS10630 dd7c75dfa3c438ae8490a7fe5d5b477f 540 SUPERFAMILY SSF51905 6 253 6.05E-70 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS10630 dd7c75dfa3c438ae8490a7fe5d5b477f 540 Gene3D G3DSA:1.20.58.100 423 537 2.1E-29 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MKLM6_RS19295 3274c8402131cdb180e81ffd0bad575c 75 Pfam PF01455 HupF/HypC family 1 67 4.7E-28 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MKLM6_RS19295 3274c8402131cdb180e81ffd0bad575c 75 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 19 35 9.1E-18 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MKLM6_RS19295 3274c8402131cdb180e81ffd0bad575c 75 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 58 70 9.1E-18 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MKLM6_RS19295 3274c8402131cdb180e81ffd0bad575c 75 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 9.1E-18 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MKLM6_RS19295 3274c8402131cdb180e81ffd0bad575c 75 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 40 56 9.1E-18 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MKLM6_RS19295 3274c8402131cdb180e81ffd0bad575c 75 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 28-03-2018 IPR019812 Hydrogenase assembly chaperone, conserved site MKLM6_RS19295 3274c8402131cdb180e81ffd0bad575c 75 SUPERFAMILY SSF159127 1 69 3.14E-24 T 28-03-2018 MKLM6_RS19295 3274c8402131cdb180e81ffd0bad575c 75 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 67 1.4E-23 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MKLM6_RS09275 4a49496a3b02f642853e8103065d90b8 161 SUPERFAMILY SSF53098 51 146 4.05E-7 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS09275 4a49496a3b02f642853e8103065d90b8 161 Gene3D G3DSA:3.30.420.10 4 156 2.9E-12 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS09275 4a49496a3b02f642853e8103065d90b8 161 Pfam PF13358 DDE superfamily endonuclease 2 136 1.6E-29 T 28-03-2018 MKLM6_RS19585 5fef5a096fe28f4a12e7535fe8f2e118 735 Pfam PF10150 Ribonuclease E/G family 120 389 2.7E-93 T 28-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 MKLM6_RS19585 5fef5a096fe28f4a12e7535fe8f2e118 735 Hamap MF_00970 Ribonuclease E [rne]. 1 733 28.979 T 28-03-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 MKLM6_RS19585 5fef5a096fe28f4a12e7535fe8f2e118 735 Pfam PF00575 S1 RNA binding domain 36 117 2.4E-10 T 28-03-2018 IPR003029 S1 domain GO:0003676 MKLM6_RS19585 5fef5a096fe28f4a12e7535fe8f2e118 735 SMART SM00316 37 118 8.6E-9 T 28-03-2018 IPR022967 RNA-binding domain, S1 MKLM6_RS19585 5fef5a096fe28f4a12e7535fe8f2e118 735 Gene3D G3DSA:2.40.50.140 32 123 1.1E-29 T 28-03-2018 MKLM6_RS19585 5fef5a096fe28f4a12e7535fe8f2e118 735 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 423 2.7E-159 T 28-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 MKLM6_RS19585 5fef5a096fe28f4a12e7535fe8f2e118 735 SUPERFAMILY SSF50249 40 123 6.86E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS12450 216abae11730f0bf9a48814ff90d51b8 338 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 19 287 8.9E-80 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MKLM6_RS12450 216abae11730f0bf9a48814ff90d51b8 338 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 8 335 48.615 T 28-03-2018 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 MKLM6_RS12450 216abae11730f0bf9a48814ff90d51b8 338 SUPERFAMILY SSF51445 7 289 1.37E-84 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily MKLM6_RS12450 216abae11730f0bf9a48814ff90d51b8 338 Gene3D G3DSA:3.20.20.300 6 331 2.3E-79 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MKLM6_RS05155 677d2f7403f984afeefa8cab39abbbff 483 SUPERFAMILY SSF158472 204 256 7.32E-8 T 28-03-2018 MKLM6_RS05155 677d2f7403f984afeefa8cab39abbbff 483 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 371 477 6.2E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS05155 677d2f7403f984afeefa8cab39abbbff 483 SUPERFAMILY SSF55874 312 477 1.96E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS05155 677d2f7403f984afeefa8cab39abbbff 483 SMART SM00304 203 258 1.5E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS05155 677d2f7403f984afeefa8cab39abbbff 483 SMART SM00388 259 322 9.6E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS05155 677d2f7403f984afeefa8cab39abbbff 483 Gene3D G3DSA:1.10.287.130 249 318 3.7E-14 T 28-03-2018 MKLM6_RS05155 677d2f7403f984afeefa8cab39abbbff 483 Pfam PF00672 HAMP domain 205 253 1.8E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS05155 677d2f7403f984afeefa8cab39abbbff 483 Gene3D G3DSA:3.30.565.10 328 483 2.5E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS05155 677d2f7403f984afeefa8cab39abbbff 483 Pfam PF00512 His Kinase A (phospho-acceptor) domain 260 322 9.3E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS05155 677d2f7403f984afeefa8cab39abbbff 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 434 1.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS05155 677d2f7403f984afeefa8cab39abbbff 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 457 1.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS05155 677d2f7403f984afeefa8cab39abbbff 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 420 1.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS05155 677d2f7403f984afeefa8cab39abbbff 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 476 1.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS05155 677d2f7403f984afeefa8cab39abbbff 483 SUPERFAMILY SSF47384 244 322 1.22E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS05155 677d2f7403f984afeefa8cab39abbbff 483 SMART SM00387 367 479 2.8E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS00905 67ffc761e11946fa6e859e3b52b17431 347 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 4 158 2.1E-11 T 28-03-2018 IPR020536 Thil, AANH domain GO:0004810 MKLM6_RS00905 67ffc761e11946fa6e859e3b52b17431 347 Gene3D G3DSA:3.40.50.620 5 207 6.2E-22 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS00905 67ffc761e11946fa6e859e3b52b17431 347 SUPERFAMILY SSF52402 2 248 1.52E-31 T 28-03-2018 MKLM6_RS12815 7ca7a6eb0935d17068504426d941be2d 651 Gene3D G3DSA:3.40.50.10190 578 649 7.5E-14 T 28-03-2018 IPR001357 BRCT domain MKLM6_RS12815 7ca7a6eb0935d17068504426d941be2d 651 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 312 382 4.8E-16 T 28-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 MKLM6_RS12815 7ca7a6eb0935d17068504426d941be2d 651 SUPERFAMILY SSF47781 387 560 1.85E-23 T 28-03-2018 IPR010994 RuvA domain 2-like MKLM6_RS12815 7ca7a6eb0935d17068504426d941be2d 651 SUPERFAMILY SSF56091 40 303 2.4E-43 T 28-03-2018 MKLM6_RS12815 7ca7a6eb0935d17068504426d941be2d 651 Gene3D G3DSA:2.40.50.140 311 379 4.1E-18 T 28-03-2018 MKLM6_RS12815 7ca7a6eb0935d17068504426d941be2d 651 Gene3D G3DSA:3.30.1490.70 106 310 2.1E-22 T 28-03-2018 MKLM6_RS12815 7ca7a6eb0935d17068504426d941be2d 651 SMART SM00532 36 429 4.2E-18 T 28-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 MKLM6_RS12815 7ca7a6eb0935d17068504426d941be2d 651 SUPERFAMILY SSF52113 570 647 1.54E-14 T 28-03-2018 IPR001357 BRCT domain MKLM6_RS12815 7ca7a6eb0935d17068504426d941be2d 651 Pfam PF14520 Helix-hairpin-helix domain 427 478 1.3E-6 T 28-03-2018 MKLM6_RS12815 7ca7a6eb0935d17068504426d941be2d 651 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 262 303 1.4E-5 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 MKLM6_RS12815 7ca7a6eb0935d17068504426d941be2d 651 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 41 229 3.7E-14 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 MKLM6_RS12815 7ca7a6eb0935d17068504426d941be2d 651 Hamap MF_01588 DNA ligase [ligA]. 38 646 33.72 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MKLM6_RS12815 7ca7a6eb0935d17068504426d941be2d 651 SMART SM00292 571 649 1.5E-7 T 28-03-2018 IPR001357 BRCT domain MKLM6_RS12815 7ca7a6eb0935d17068504426d941be2d 651 SUPERFAMILY SSF50249 308 384 2.4E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS12815 7ca7a6eb0935d17068504426d941be2d 651 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 571 646 1.1E-9 T 28-03-2018 IPR001357 BRCT domain MKLM6_RS12815 7ca7a6eb0935d17068504426d941be2d 651 PIRSF PIRSF001604 246 650 5.4E-103 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MKLM6_RS12815 7ca7a6eb0935d17068504426d941be2d 651 PIRSF PIRSF001604 26 253 1.2E-17 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MKLM6_RS12815 7ca7a6eb0935d17068504426d941be2d 651 Gene3D G3DSA:1.10.150.20 428 480 3.8E-9 T 28-03-2018 MKLM6_RS12815 7ca7a6eb0935d17068504426d941be2d 651 Gene3D G3DSA:1.10.150.20 481 545 2.3E-5 T 28-03-2018 MKLM6_RS07540 98943ba86fc7db51bf60d2a61b984800 169 Gene3D G3DSA:1.20.120.450 1 166 5.5E-63 T 28-03-2018 MKLM6_RS07540 98943ba86fc7db51bf60d2a61b984800 169 SUPERFAMILY SSF109854 4 167 4.3E-57 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MKLM6_RS07540 98943ba86fc7db51bf60d2a61b984800 169 Pfam PF09351 Domain of unknown function (DUF1993) 5 165 4.4E-57 T 28-03-2018 IPR018531 Domain of unknown function DUF1993 MKLM6_RS15925 9a50c674f474cb81761c57458e12ca8e 183 SUPERFAMILY SSF143422 1 143 1.57E-33 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS15925 9a50c674f474cb81761c57458e12ca8e 183 Gene3D G3DSA:3.30.70.1290 1 143 6.7E-34 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS15925 9a50c674f474cb81761c57458e12ca8e 183 SMART SM01321 9 137 7.0E-33 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS15925 9a50c674f474cb81761c57458e12ca8e 183 Pfam PF01797 Transposase IS200 like 13 134 2.9E-7 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS00550 968bf02d10ef10626fe0d035a548f091 184 Pfam PF13673 Acetyltransferase (GNAT) domain 45 146 7.4E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 MKLM6_RS00550 968bf02d10ef10626fe0d035a548f091 184 SUPERFAMILY SSF55729 4 148 9.79E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS00550 968bf02d10ef10626fe0d035a548f091 184 Gene3D G3DSA:3.40.630.30 2 160 3.3E-24 T 28-03-2018 MKLM6_RS13370 06afe22b84db4290cbbb1bb4bb216160 660 Pfam PF00593 TonB dependent receptor 242 658 1.2E-37 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS13370 06afe22b84db4290cbbb1bb4bb216160 660 Pfam PF07715 TonB-dependent Receptor Plug Domain 48 157 5.8E-14 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS13370 06afe22b84db4290cbbb1bb4bb216160 660 Gene3D G3DSA:2.170.130.10 30 165 5.7E-18 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS13370 06afe22b84db4290cbbb1bb4bb216160 660 Gene3D G3DSA:2.40.170.20 166 660 4.9E-50 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS13370 06afe22b84db4290cbbb1bb4bb216160 660 SUPERFAMILY SSF56935 38 660 4.03E-79 T 28-03-2018 MKLM6_RS21870 62960f2641eb196a018feb80aa03577c 190 Pfam PF04060 Putative Fe-S cluster 16 48 1.7E-16 T 28-03-2018 IPR007202 4Fe-4S domain GO:0051536 MKLM6_RS21870 62960f2641eb196a018feb80aa03577c 190 SUPERFAMILY SSF54862 11 138 1.79E-26 T 28-03-2018 MKLM6_RS21870 62960f2641eb196a018feb80aa03577c 190 Pfam PF14697 4Fe-4S dicluster domain 81 135 2.1E-15 T 28-03-2018 MKLM6_RS21870 62960f2641eb196a018feb80aa03577c 190 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 88 99 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MKLM6_RS21870 62960f2641eb196a018feb80aa03577c 190 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 4 145 2.5E-62 T 28-03-2018 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 MKLM6_RS21870 62960f2641eb196a018feb80aa03577c 190 PIRSF PIRSF005784 1 158 5.6E-61 T 28-03-2018 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 MKLM6_RS21870 62960f2641eb196a018feb80aa03577c 190 Gene3D G3DSA:3.30.70.20 1 93 5.1E-8 T 28-03-2018 MKLM6_RS21870 62960f2641eb196a018feb80aa03577c 190 Gene3D G3DSA:3.30.70.20 94 189 7.2E-18 T 28-03-2018 MKLM6_RS21870 62960f2641eb196a018feb80aa03577c 190 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 118 129 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MKLM6_RS00330 5038ae183b5c8d9a6fefded0da81f925 199 Pfam PF02517 CAAX protease self-immunity 93 182 4.1E-18 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 MKLM6_RS10025 02ebc9352ccad9fcc9efb1724ebaa676 335 Pfam PF16220 Domain of unknown function (DUF4880) 15 57 1.0E-12 T 28-03-2018 IPR032623 FecR, N-terminal MKLM6_RS10025 02ebc9352ccad9fcc9efb1724ebaa676 335 PIRSF PIRSF018266 5 335 4.4E-82 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component MKLM6_RS10025 02ebc9352ccad9fcc9efb1724ebaa676 335 Pfam PF04773 FecR protein 132 224 1.3E-21 T 28-03-2018 IPR006860 FecR protein MKLM6_RS09095 c0e5ca331eb7cdbab86b1271152419ff 457 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 103 447 1.2E-120 T 28-03-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 MKLM6_RS09095 c0e5ca331eb7cdbab86b1271152419ff 457 Gene3D G3DSA:3.60.120.10 5 454 1.6E-161 T 28-03-2018 IPR005801 ADC synthase GO:0009058 MKLM6_RS09095 c0e5ca331eb7cdbab86b1271152419ff 457 Pfam PF00425 chorismate binding enzyme 191 444 1.2E-99 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal MKLM6_RS09095 c0e5ca331eb7cdbab86b1271152419ff 457 SUPERFAMILY SSF56322 18 452 2.35E-151 T 28-03-2018 IPR005801 ADC synthase GO:0009058 MKLM6_RS09095 c0e5ca331eb7cdbab86b1271152419ff 457 PRINTS PR00095 Anthranilate synthase component I signature 401 415 1.0E-18 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MKLM6_RS09095 c0e5ca331eb7cdbab86b1271152419ff 457 PRINTS PR00095 Anthranilate synthase component I signature 386 400 1.0E-18 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MKLM6_RS09095 c0e5ca331eb7cdbab86b1271152419ff 457 PRINTS PR00095 Anthranilate synthase component I signature 292 305 1.0E-18 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MKLM6_RS09095 c0e5ca331eb7cdbab86b1271152419ff 457 PRINTS PR00095 Anthranilate synthase component I signature 306 319 1.0E-18 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MKLM6_RS09095 c0e5ca331eb7cdbab86b1271152419ff 457 Pfam PF04715 Anthranilate synthase component I, N terminal region 19 149 2.2E-26 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MKLM6_RS04915 42931d8f459dd0d3e9b3ef422641cb2f 131 Gene3D G3DSA:2.170.150.20 2 131 4.1E-59 T 28-03-2018 MKLM6_RS04915 42931d8f459dd0d3e9b3ef422641cb2f 131 SUPERFAMILY SSF51316 8 129 1.41E-57 T 28-03-2018 IPR011057 Mss4-like MKLM6_RS04915 42931d8f459dd0d3e9b3ef422641cb2f 131 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 2 130 36.652 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MKLM6_RS04915 42931d8f459dd0d3e9b3ef422641cb2f 131 Pfam PF01641 SelR domain 11 127 2.6E-55 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MKLM6_RS04915 42931d8f459dd0d3e9b3ef422641cb2f 131 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 9 126 1.3E-54 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MKLM6_RS08140 39f4dd10e13d3ca1a7a5f1fa92e4704f 240 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 23 226 4.5E-46 T 28-03-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 MKLM6_RS08140 39f4dd10e13d3ca1a7a5f1fa92e4704f 240 Gene3D G3DSA:3.40.430.10 3 233 2.0E-62 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 MKLM6_RS08140 39f4dd10e13d3ca1a7a5f1fa92e4704f 240 SUPERFAMILY SSF53597 21 227 8.51E-52 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 MKLM6_RS08140 39f4dd10e13d3ca1a7a5f1fa92e4704f 240 Pfam PF01872 RibD C-terminal domain 24 225 1.9E-44 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MKLM6_RS02625 76a47cad3c4e48de3c8571319bf9d2dd 429 Gene3D G3DSA:1.10.3210.10 149 388 2.1E-37 T 28-03-2018 MKLM6_RS02625 76a47cad3c4e48de3c8571319bf9d2dd 429 SUPERFAMILY SSF51206 25 131 2.62E-9 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like MKLM6_RS02625 76a47cad3c4e48de3c8571319bf9d2dd 429 Pfam PF08668 HDOD domain 171 349 1.8E-36 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD MKLM6_RS02625 76a47cad3c4e48de3c8571319bf9d2dd 429 SUPERFAMILY SSF109604 155 422 1.26E-48 T 28-03-2018 MKLM6_RS02625 76a47cad3c4e48de3c8571319bf9d2dd 429 Gene3D G3DSA:2.60.120.10 8 148 2.0E-5 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS11620 432f5ceb7ba163d6bdac89c7872fe048 772 Pfam PF02421 Ferrous iron transport protein B 7 164 1.2E-66 T 28-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 MKLM6_RS11620 432f5ceb7ba163d6bdac89c7872fe048 772 Pfam PF07664 Ferrous iron transport protein B C terminus 463 515 7.1E-21 T 28-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 MKLM6_RS11620 432f5ceb7ba163d6bdac89c7872fe048 772 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 12 704 2.6E-192 T 28-03-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 MKLM6_RS11620 432f5ceb7ba163d6bdac89c7872fe048 772 Gene3D G3DSA:3.40.50.300 2 289 3.1E-40 T 28-03-2018 MKLM6_RS11620 432f5ceb7ba163d6bdac89c7872fe048 772 Pfam PF07670 Nucleoside recognition 521 706 3.8E-32 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 MKLM6_RS11620 432f5ceb7ba163d6bdac89c7872fe048 772 Pfam PF07670 Nucleoside recognition 360 452 3.4E-13 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 MKLM6_RS11620 432f5ceb7ba163d6bdac89c7872fe048 772 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 29 47 7.3E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS11620 432f5ceb7ba163d6bdac89c7872fe048 772 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 8 28 7.3E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS11620 432f5ceb7ba163d6bdac89c7872fe048 772 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 165 4.9E-19 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MKLM6_RS11620 432f5ceb7ba163d6bdac89c7872fe048 772 SUPERFAMILY SSF52540 6 173 5.47E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS12110 802177c37c7bbb82d181188193e2a1cd 228 Pfam PF00119 ATP synthase A chain 19 210 4.9E-38 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12110 802177c37c7bbb82d181188193e2a1cd 228 SUPERFAMILY SSF81336 72 210 2.48E-31 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12110 802177c37c7bbb82d181188193e2a1cd 228 PRINTS PR00123 ATP synthase A subunit signature 153 175 3.7E-17 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12110 802177c37c7bbb82d181188193e2a1cd 228 PRINTS PR00123 ATP synthase A subunit signature 197 212 3.7E-17 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12110 802177c37c7bbb82d181188193e2a1cd 228 PRINTS PR00123 ATP synthase A subunit signature 77 93 3.7E-17 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12110 802177c37c7bbb82d181188193e2a1cd 228 PRINTS PR00123 ATP synthase A subunit signature 137 152 3.7E-17 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12110 802177c37c7bbb82d181188193e2a1cd 228 ProSitePatterns PS00449 ATP synthase a subunit signature. 156 165 - T 28-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12110 802177c37c7bbb82d181188193e2a1cd 228 Gene3D G3DSA:1.20.120.220 48 217 1.0E-35 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12110 802177c37c7bbb82d181188193e2a1cd 228 Hamap MF_01393 ATP synthase subunit a [atpB]. 6 217 13.96 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS13405 179e4c1441cd4234432ca57ccd75353a 609 ProSitePatterns PS00211 ABC transporters family signature. 510 524 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS13405 179e4c1441cd4234432ca57ccd75353a 609 Pfam PF00005 ABC transporter 390 538 3.2E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS13405 179e4c1441cd4234432ca57ccd75353a 609 Gene3D G3DSA:1.20.1560.10 19 359 2.1E-42 T 28-03-2018 MKLM6_RS13405 179e4c1441cd4234432ca57ccd75353a 609 Pfam PF00664 ABC transporter transmembrane region 92 327 1.2E-28 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MKLM6_RS13405 179e4c1441cd4234432ca57ccd75353a 609 Gene3D G3DSA:3.40.50.300 368 609 2.4E-70 T 28-03-2018 MKLM6_RS13405 179e4c1441cd4234432ca57ccd75353a 609 SUPERFAMILY SSF90123 26 357 1.44E-49 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MKLM6_RS13405 179e4c1441cd4234432ca57ccd75353a 609 SMART SM00382 399 575 2.1E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS13405 179e4c1441cd4234432ca57ccd75353a 609 SUPERFAMILY SSF52540 371 606 1.52E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS18090 acb24de46b6f92b8f477eac3a5c475e0 575 SUPERFAMILY SSF52540 321 553 3.49E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS18090 acb24de46b6f92b8f477eac3a5c475e0 575 Pfam PF00005 ABC transporter 347 493 2.5E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS18090 acb24de46b6f92b8f477eac3a5c475e0 575 Pfam PF00664 ABC transporter transmembrane region 25 276 1.5E-13 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MKLM6_RS18090 acb24de46b6f92b8f477eac3a5c475e0 575 Gene3D G3DSA:3.40.50.300 315 571 1.0E-64 T 28-03-2018 MKLM6_RS18090 acb24de46b6f92b8f477eac3a5c475e0 575 ProSitePatterns PS00211 ABC transporters family signature. 466 480 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS18090 acb24de46b6f92b8f477eac3a5c475e0 575 SUPERFAMILY SSF90123 11 316 7.85E-43 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MKLM6_RS18090 acb24de46b6f92b8f477eac3a5c475e0 575 SMART SM00382 355 548 7.1E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS18090 acb24de46b6f92b8f477eac3a5c475e0 575 TIGRFAM TIGR01842 type_I_sec_PrtD: type I secretion system ATPase 13 555 1.8E-222 T 28-03-2018 IPR010128 ATPase, type I secretion system, PrtD GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 MKLM6_RS18090 acb24de46b6f92b8f477eac3a5c475e0 575 Gene3D G3DSA:1.20.1560.10 4 314 2.5E-24 T 28-03-2018 MKLM6_RS02805 9178c281fe682359c0f3e9a689a9d0a4 157 SUPERFAMILY SSF50341 8 150 5.49E-42 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS02805 9178c281fe682359c0f3e9a689a9d0a4 157 SMART SM00260 9 146 3.1E-45 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS02805 9178c281fe682359c0f3e9a689a9d0a4 157 Gene3D G3DSA:2.40.50.180 30 94 1.3E-23 T 28-03-2018 MKLM6_RS02805 9178c281fe682359c0f3e9a689a9d0a4 157 Pfam PF01584 CheW-like domain 13 148 5.0E-40 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS02805 9178c281fe682359c0f3e9a689a9d0a4 157 Gene3D G3DSA:2.30.30.40 95 140 4.6E-17 T 28-03-2018 MKLM6_RS06655 ba6bdc4c836da04a813ef5a1f7fa7e97 109 SUPERFAMILY SSF143011 1 96 5.89E-5 T 28-03-2018 IPR035095 Toxin RelE-like domain MKLM6_RS06655 ba6bdc4c836da04a813ef5a1f7fa7e97 109 Gene3D G3DSA:3.30.2310.20 1 98 8.0E-9 T 28-03-2018 MKLM6_RS06655 ba6bdc4c836da04a813ef5a1f7fa7e97 109 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 96 2.8E-15 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MKLM6_RS09495 b68c17fbeef986398397c2f6c6000ac4 339 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 338 7.1E-107 T 28-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MKLM6_RS09495 b68c17fbeef986398397c2f6c6000ac4 339 Pfam PF01409 tRNA synthetases class II core domain (F) 93 338 5.9E-106 T 28-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 MKLM6_RS09495 b68c17fbeef986398397c2f6c6000ac4 339 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 338 49.4 T 28-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 MKLM6_RS09495 b68c17fbeef986398397c2f6c6000ac4 339 SUPERFAMILY SSF46589 14 100 8.37E-23 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 MKLM6_RS09495 b68c17fbeef986398397c2f6c6000ac4 339 SUPERFAMILY SSF55681 93 339 1.04E-83 T 28-03-2018 MKLM6_RS09495 b68c17fbeef986398397c2f6c6000ac4 339 Gene3D G3DSA:3.30.930.10 8 339 5.4E-89 T 28-03-2018 MKLM6_RS09495 b68c17fbeef986398397c2f6c6000ac4 339 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 20 88 2.6E-24 T 28-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MKLM6_RS08495 241f0d2a3bd2ec5a9aff24a45d17b664 576 Gene3D G3DSA:3.30.200.20 260 335 7.7E-8 T 28-03-2018 MKLM6_RS08495 241f0d2a3bd2ec5a9aff24a45d17b664 576 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 387 399 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MKLM6_RS08495 241f0d2a3bd2ec5a9aff24a45d17b664 576 SUPERFAMILY SSF56112 263 527 3.37E-54 T 28-03-2018 IPR011009 Protein kinase-like domain MKLM6_RS08495 241f0d2a3bd2ec5a9aff24a45d17b664 576 SUPERFAMILY SSF81606 7 236 5.62E-52 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS08495 241f0d2a3bd2ec5a9aff24a45d17b664 576 Gene3D G3DSA:1.10.510.10 336 543 3.0E-41 T 28-03-2018 MKLM6_RS08495 241f0d2a3bd2ec5a9aff24a45d17b664 576 SMART SM00331 21 235 1.2E-18 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS08495 241f0d2a3bd2ec5a9aff24a45d17b664 576 Pfam PF00069 Protein kinase domain 281 495 1.1E-36 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MKLM6_RS08495 241f0d2a3bd2ec5a9aff24a45d17b664 576 Gene3D G3DSA:3.60.40.10 2 250 8.5E-36 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS08495 241f0d2a3bd2ec5a9aff24a45d17b664 576 SMART SM00332 1 233 9.3E-20 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS08495 241f0d2a3bd2ec5a9aff24a45d17b664 576 Pfam PF13672 Protein phosphatase 2C 18 196 2.4E-13 T 28-03-2018 MKLM6_RS08495 241f0d2a3bd2ec5a9aff24a45d17b664 576 SMART SM00220 268 530 1.0E-16 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MKLM6_RS15640 74fc0e9ecd550a15f73af407840ac37b 166 SUPERFAMILY SSF111384 20 161 7.59E-32 T 28-03-2018 IPR024930 Skp domain MKLM6_RS15640 74fc0e9ecd550a15f73af407840ac37b 166 PIRSF PIRSF002094 1 164 6.9E-49 T 28-03-2018 IPR005632 Chaperone protein Skp GO:0051082 MKLM6_RS15640 74fc0e9ecd550a15f73af407840ac37b 166 SMART SM00935 9 162 1.2E-46 T 28-03-2018 IPR005632 Chaperone protein Skp GO:0051082 MKLM6_RS15640 74fc0e9ecd550a15f73af407840ac37b 166 Gene3D G3DSA:3.30.910.20 9 162 1.3E-20 T 28-03-2018 MKLM6_RS15640 74fc0e9ecd550a15f73af407840ac37b 166 Pfam PF03938 Outer membrane protein (OmpH-like) 9 161 1.2E-30 T 28-03-2018 IPR005632 Chaperone protein Skp GO:0051082 MKLM6_RS21715 3191e270d62485bc9e4b5c604e3aa4eb 1125 SUPERFAMILY SSF52540 993 1081 6.88E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS21715 3191e270d62485bc9e4b5c604e3aa4eb 1125 SUPERFAMILY SSF52540 23 130 6.88E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS21715 3191e270d62485bc9e4b5c604e3aa4eb 1125 SUPERFAMILY SSF52540 314 338 6.88E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS21715 3191e270d62485bc9e4b5c604e3aa4eb 1125 Gene3D G3DSA:3.40.50.300 22 502 3.3E-14 T 28-03-2018 MKLM6_RS21715 3191e270d62485bc9e4b5c604e3aa4eb 1125 Pfam PF13555 P-loop containing region of AAA domain 24 84 4.3E-25 T 28-03-2018 MKLM6_RS21715 3191e270d62485bc9e4b5c604e3aa4eb 1125 Pfam PF13558 Putative exonuclease SbcCD, C subunit 980 1070 1.8E-23 T 28-03-2018 MKLM6_RS21715 3191e270d62485bc9e4b5c604e3aa4eb 1125 Gene3D G3DSA:3.40.50.300 582 1119 4.4E-9 T 28-03-2018 MKLM6_RS04910 f15c60036a76290ddda5ed7e194314d3 433 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 308 324 3.6E-39 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 MKLM6_RS04910 f15c60036a76290ddda5ed7e194314d3 433 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 265 283 3.6E-39 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 MKLM6_RS04910 f15c60036a76290ddda5ed7e194314d3 433 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 77 93 3.6E-39 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 MKLM6_RS04910 f15c60036a76290ddda5ed7e194314d3 433 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 110 130 3.6E-39 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 MKLM6_RS04910 f15c60036a76290ddda5ed7e194314d3 433 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 397 412 3.6E-39 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 MKLM6_RS04910 f15c60036a76290ddda5ed7e194314d3 433 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 146 163 3.6E-39 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 MKLM6_RS04910 f15c60036a76290ddda5ed7e194314d3 433 SUPERFAMILY SSF53187 6 88 1.21E-93 T 28-03-2018 MKLM6_RS04910 f15c60036a76290ddda5ed7e194314d3 433 SUPERFAMILY SSF53187 214 430 1.21E-93 T 28-03-2018 MKLM6_RS04910 f15c60036a76290ddda5ed7e194314d3 433 Gene3D G3DSA:3.40.630.10 205 433 8.3E-68 T 28-03-2018 MKLM6_RS04910 f15c60036a76290ddda5ed7e194314d3 433 Gene3D G3DSA:3.40.630.10 1 98 1.4E-30 T 28-03-2018 MKLM6_RS04910 f15c60036a76290ddda5ed7e194314d3 433 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 13 430 6.3E-119 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 MKLM6_RS04910 f15c60036a76290ddda5ed7e194314d3 433 SUPERFAMILY SSF101821 89 213 5.49E-26 T 28-03-2018 MKLM6_RS04910 f15c60036a76290ddda5ed7e194314d3 433 Gene3D G3DSA:2.30.250.10 99 204 2.0E-35 T 28-03-2018 MKLM6_RS08590 54cf969aa1385febd05539627c362700 845 Pfam PF13181 Tetratricopeptide repeat 531 560 0.19 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS08590 54cf969aa1385febd05539627c362700 845 SUPERFAMILY SSF48452 535 693 8.54E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS08590 54cf969aa1385febd05539627c362700 845 SUPERFAMILY SSF52540 23 264 6.59E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS08590 54cf969aa1385febd05539627c362700 845 SUPERFAMILY SSF46785 298 366 1.47E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS08590 54cf969aa1385febd05539627c362700 845 Gene3D G3DSA:1.25.40.120 600 844 8.3E-13 T 28-03-2018 MKLM6_RS08590 54cf969aa1385febd05539627c362700 845 SMART SM00418 291 369 9.1E-4 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MKLM6_RS08590 54cf969aa1385febd05539627c362700 845 Gene3D G3DSA:3.40.50.300 11 204 3.5E-9 T 28-03-2018 MKLM6_RS08590 54cf969aa1385febd05539627c362700 845 SMART SM00028 530 563 8.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS08590 54cf969aa1385febd05539627c362700 845 SMART SM00028 606 639 1.7E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS08590 54cf969aa1385febd05539627c362700 845 SMART SM00028 644 677 110.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS08590 54cf969aa1385febd05539627c362700 845 SMART SM00028 568 601 12.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS08590 54cf969aa1385febd05539627c362700 845 Gene3D G3DSA:1.25.40.10 548 599 6.8E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS08590 54cf969aa1385febd05539627c362700 845 Gene3D G3DSA:1.10.10.10 223 386 6.7E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS08590 54cf969aa1385febd05539627c362700 845 Gene3D G3DSA:1.25.40.10 451 547 1.5E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS08590 54cf969aa1385febd05539627c362700 845 Pfam PF01022 Bacterial regulatory protein, arsR family 298 344 1.8E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MKLM6_RS08590 54cf969aa1385febd05539627c362700 845 Pfam PF13174 Tetratricopeptide repeat 608 634 0.15 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS20655 0888ca86c84032f514bc6798d4dc62d8 277 TIGRFAM TIGR03370 VPLPA-CTERM: VPLPA-CTERM protein sorting domain 249 272 1.3E-7 T 28-03-2018 IPR022472 VPLPA-CTERM protein sorting domain MKLM6_RS05090 9d354e9388b1ba8cca7ea51f9a1530f5 218 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 189 206 0.0013 T 28-03-2018 IPR013424 PEP-CTERM protein-sorting domain MKLM6_RS01845 6e8609b283ff4f7f12e203869b86777e 1032 Gene3D G3DSA:1.10.10.160 85 182 1.5E-21 T 28-03-2018 MKLM6_RS01845 6e8609b283ff4f7f12e203869b86777e 1032 SUPERFAMILY SSF52980 746 1028 2.47E-48 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MKLM6_RS01845 6e8609b283ff4f7f12e203869b86777e 1032 TIGRFAM TIGR01450 recC: exodeoxyribonuclease V, gamma subunit 2 978 3.0E-240 T 28-03-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 MKLM6_RS01845 6e8609b283ff4f7f12e203869b86777e 1032 Gene3D G3DSA:3.40.50.300 293 735 1.5E-49 T 28-03-2018 MKLM6_RS01845 6e8609b283ff4f7f12e203869b86777e 1032 SUPERFAMILY SSF52540 1 309 1.38E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS01845 6e8609b283ff4f7f12e203869b86777e 1032 Hamap MF_01486 RecBCD enzyme subunit RecC [recC]. 1 1032 18.32 T 28-03-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 MKLM6_RS01845 6e8609b283ff4f7f12e203869b86777e 1032 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 1 728 1.0E-231 T 28-03-2018 MKLM6_RS01845 6e8609b283ff4f7f12e203869b86777e 1032 SUPERFAMILY SSF52540 309 735 9.16E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS01845 6e8609b283ff4f7f12e203869b86777e 1032 PIRSF PIRSF000980 1 1024 1.8E-266 T 28-03-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 MKLM6_RS11615 d3f59b815810943db74e0572bbaefaac 74 Pfam PF09012 FeoC like transcriptional regulator 2 71 4.5E-23 T 28-03-2018 IPR015102 Transcriptional regulator HTH-type, FeoC MKLM6_RS11615 d3f59b815810943db74e0572bbaefaac 74 SUPERFAMILY SSF46785 1 73 1.02E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS11615 d3f59b815810943db74e0572bbaefaac 74 Gene3D G3DSA:1.10.10.10 1 71 1.7E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS17390 1d33463baf88431029a37a768f8f4f8d 66 Gene3D G3DSA:3.30.70.20 3 63 6.1E-11 T 28-03-2018 MKLM6_RS17390 1d33463baf88431029a37a768f8f4f8d 66 Pfam PF00037 4Fe-4S binding domain 4 26 1.2E-6 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MKLM6_RS17390 1d33463baf88431029a37a768f8f4f8d 66 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 10 21 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MKLM6_RS17390 1d33463baf88431029a37a768f8f4f8d 66 SUPERFAMILY SSF54862 4 59 9.07E-13 T 28-03-2018 MKLM6_RS03030 4a2fb997e85df00885f59140ef84bf99 386 Pfam PF02772 S-adenosylmethionine synthetase, central domain 115 232 1.6E-44 T 28-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MKLM6_RS03030 4a2fb997e85df00885f59140ef84bf99 386 SUPERFAMILY SSF55973 112 233 1.14E-50 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MKLM6_RS03030 4a2fb997e85df00885f59140ef84bf99 386 PIRSF PIRSF000497 1 385 4.8E-175 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MKLM6_RS03030 4a2fb997e85df00885f59140ef84bf99 386 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 3 384 58.162 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MKLM6_RS03030 4a2fb997e85df00885f59140ef84bf99 386 SUPERFAMILY SSF55973 234 385 2.75E-69 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MKLM6_RS03030 4a2fb997e85df00885f59140ef84bf99 386 Gene3D G3DSA:3.30.300.10 12 134 6.4E-44 T 28-03-2018 MKLM6_RS03030 4a2fb997e85df00885f59140ef84bf99 386 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 6 383 2.9E-188 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MKLM6_RS03030 4a2fb997e85df00885f59140ef84bf99 386 Gene3D G3DSA:3.30.300.10 247 386 9.4E-49 T 28-03-2018 MKLM6_RS03030 4a2fb997e85df00885f59140ef84bf99 386 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 117 127 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MKLM6_RS03030 4a2fb997e85df00885f59140ef84bf99 386 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 234 373 2.1E-68 T 28-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MKLM6_RS03030 4a2fb997e85df00885f59140ef84bf99 386 Gene3D G3DSA:3.30.300.10 135 234 2.6E-41 T 28-03-2018 MKLM6_RS03030 4a2fb997e85df00885f59140ef84bf99 386 SUPERFAMILY SSF55973 4 111 3.61E-47 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MKLM6_RS03030 4a2fb997e85df00885f59140ef84bf99 386 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 260 268 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MKLM6_RS03030 4a2fb997e85df00885f59140ef84bf99 386 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 4 102 6.4E-43 T 28-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MKLM6_RS19940 b7963e43ace140baa7b6177043157b40 260 Pfam PF02405 Permease MlaE 43 255 2.9E-74 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 MKLM6_RS19940 b7963e43ace140baa7b6177043157b40 260 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 5 257 5.5E-87 T 28-03-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria MKLM6_RS18310 21f585d609754a2267afccd43ced30d8 126 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 25.579 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18310 21f585d609754a2267afccd43ced30d8 126 Pfam PF01196 Ribosomal protein L17 20 116 1.0E-33 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18310 21f585d609754a2267afccd43ced30d8 126 SUPERFAMILY SSF64263 1 118 2.75E-48 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18310 21f585d609754a2267afccd43ced30d8 126 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 4.8E-44 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18310 21f585d609754a2267afccd43ced30d8 126 Gene3D G3DSA:3.90.1030.10 1 117 2.7E-48 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18310 21f585d609754a2267afccd43ced30d8 126 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS08160 b3df50a369246363456a7f860e82b40d 469 Pfam PF14269 Arylsulfotransferase (ASST) 134 415 1.2E-20 T 28-03-2018 MKLM6_RS08160 b3df50a369246363456a7f860e82b40d 469 Gene3D G3DSA:2.120.10.30 96 434 4.4E-4 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MKLM6_RS08160 b3df50a369246363456a7f860e82b40d 469 SUPERFAMILY SSF50998 331 415 1.0E-6 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MKLM6_RS08160 b3df50a369246363456a7f860e82b40d 469 SUPERFAMILY SSF50998 265 285 1.0E-6 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MKLM6_RS08160 b3df50a369246363456a7f860e82b40d 469 SUPERFAMILY SSF50998 190 227 1.0E-6 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MKLM6_RS19090 b29e8db7e05bfb4789c67934e287ce75 519 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 9 501 1.6E-175 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MKLM6_RS19090 b29e8db7e05bfb4789c67934e287ce75 519 PIRSF PIRSF006446 349 516 1.8E-36 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MKLM6_RS19090 b29e8db7e05bfb4789c67934e287ce75 519 PIRSF PIRSF006446 2 327 1.0E-115 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MKLM6_RS06845 f474ec97e44195f74d6981d024b4c87e 322 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 233 322 3.4E-35 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MKLM6_RS06845 f474ec97e44195f74d6981d024b4c87e 322 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 3 322 68.978 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MKLM6_RS06845 f474ec97e44195f74d6981d024b4c87e 322 SUPERFAMILY SSF53901 6 322 1.37E-71 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS06845 f474ec97e44195f74d6981d024b4c87e 322 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 108 185 1.6E-33 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MKLM6_RS06845 f474ec97e44195f74d6981d024b4c87e 322 Gene3D G3DSA:3.40.47.10 164 322 2.4E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS06845 f474ec97e44195f74d6981d024b4c87e 322 Gene3D G3DSA:3.40.47.10 2 163 1.2E-40 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS06845 f474ec97e44195f74d6981d024b4c87e 322 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 5 321 2.0E-133 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MKLM6_RS00640 7362d58420ec7dda83fb588436d37d7b 287 PRINTS PR00126 ATP synthase gamma subunit signature 265 286 3.0E-36 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00640 7362d58420ec7dda83fb588436d37d7b 287 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 3.0E-36 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00640 7362d58420ec7dda83fb588436d37d7b 287 PRINTS PR00126 ATP synthase gamma subunit signature 234 253 3.0E-36 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00640 7362d58420ec7dda83fb588436d37d7b 287 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 3.0E-36 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00640 7362d58420ec7dda83fb588436d37d7b 287 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 287 1.1E-105 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00640 7362d58420ec7dda83fb588436d37d7b 287 SUPERFAMILY SSF52943 5 287 1.28E-92 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00640 7362d58420ec7dda83fb588436d37d7b 287 Pfam PF00231 ATP synthase 5 286 1.2E-92 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00640 7362d58420ec7dda83fb588436d37d7b 287 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 287 35.298 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00640 7362d58420ec7dda83fb588436d37d7b 287 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 273 286 - T 28-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS00640 7362d58420ec7dda83fb588436d37d7b 287 Gene3D G3DSA:3.40.1380.10 42 239 3.5E-68 T 28-03-2018 MKLM6_RS00640 7362d58420ec7dda83fb588436d37d7b 287 Gene3D G3DSA:1.10.287.80 2 41 8.8E-16 T 28-03-2018 MKLM6_RS00640 7362d58420ec7dda83fb588436d37d7b 287 Gene3D G3DSA:1.10.287.80 240 282 2.4E-14 T 28-03-2018 MKLM6_RS02875 8857c97c633c3ba7cdeba75b0a7c26aa 24 Pfam PF08042 PqqA family 2 20 5.5E-11 T 28-03-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 MKLM6_RS02875 8857c97c633c3ba7cdeba75b0a7c26aa 24 Hamap MF_00656 Coenzyme PQQ synthesis protein A [pqqA]. 2 24 11.105 T 28-03-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 MKLM6_RS02875 8857c97c633c3ba7cdeba75b0a7c26aa 24 TIGRFAM TIGR02107 PQQ_syn_pqqA: coenzyme PQQ precursor peptide PqqA 3 23 4.6E-13 T 28-03-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 MKLM6_RS21635 644642f70a101e44b55b2f036830ad57 106 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 2 66 3.2E-21 T 28-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 MKLM6_RS21635 644642f70a101e44b55b2f036830ad57 106 Pfam PF02416 mttA/Hcf106 family 4 33 1.7E-6 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 MKLM6_RS21635 644642f70a101e44b55b2f036830ad57 106 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 103 14.038 T 28-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 MKLM6_RS21635 644642f70a101e44b55b2f036830ad57 106 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 3.3E-20 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 MKLM6_RS21635 644642f70a101e44b55b2f036830ad57 106 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 3.3E-20 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 MKLM6_RS21635 644642f70a101e44b55b2f036830ad57 106 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 3.3E-20 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 MKLM6_RS21075 0b47bf0d84b91e2f7a5245da3016ae36 434 SUPERFAMILY SSF81301 6 156 1.85E-41 T 28-03-2018 MKLM6_RS21075 0b47bf0d84b91e2f7a5245da3016ae36 434 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 3 429 1.8E-153 T 28-03-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 MKLM6_RS21075 0b47bf0d84b91e2f7a5245da3016ae36 434 Gene3D G3DSA:3.30.460.10 1 160 8.3E-55 T 28-03-2018 MKLM6_RS21075 0b47bf0d84b91e2f7a5245da3016ae36 434 Pfam PF01743 Poly A polymerase head domain 34 162 6.7E-38 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MKLM6_RS21075 0b47bf0d84b91e2f7a5245da3016ae36 434 SUPERFAMILY SSF81891 162 396 4.32E-46 T 28-03-2018 MKLM6_RS21075 0b47bf0d84b91e2f7a5245da3016ae36 434 Gene3D G3DSA:1.10.3090.10 162 406 2.1E-40 T 28-03-2018 MKLM6_RS21075 0b47bf0d84b91e2f7a5245da3016ae36 434 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 190 251 2.1E-20 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MKLM6_RS21075 0b47bf0d84b91e2f7a5245da3016ae36 434 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 2 431 37.099 T 28-03-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 MKLM6_RS21075 0b47bf0d84b91e2f7a5245da3016ae36 434 Pfam PF12626 Polymerase A arginine-rich C-terminus 307 422 5.0E-38 T 28-03-2018 IPR025866 Polymerase A arginine-rich C-terminal domain MKLM6_RS19420 3e83a24d915bc6275c11994afaac49e1 69 SMART SM00357 6 69 1.7E-29 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 MKLM6_RS19420 3e83a24d915bc6275c11994afaac49e1 69 Pfam PF00313 'Cold-shock' DNA-binding domain 6 68 6.3E-29 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MKLM6_RS19420 3e83a24d915bc6275c11994afaac49e1 69 PIRSF PIRSF002599 1 69 1.8E-24 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 MKLM6_RS19420 3e83a24d915bc6275c11994afaac49e1 69 SUPERFAMILY SSF50249 3 68 1.72E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS19420 3e83a24d915bc6275c11994afaac49e1 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 36 - T 28-03-2018 IPR019844 Cold-shock conserved site MKLM6_RS19420 3e83a24d915bc6275c11994afaac49e1 69 Gene3D G3DSA:2.40.50.140 2 69 1.1E-27 T 28-03-2018 MKLM6_RS19420 3e83a24d915bc6275c11994afaac49e1 69 PRINTS PR00050 Cold shock protein signature 7 22 4.1E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MKLM6_RS19420 3e83a24d915bc6275c11994afaac49e1 69 PRINTS PR00050 Cold shock protein signature 27 36 4.1E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MKLM6_RS19420 3e83a24d915bc6275c11994afaac49e1 69 PRINTS PR00050 Cold shock protein signature 42 60 4.1E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MKLM6_RS21070 195b32b695361581ad3f89dbf6de8d4a 167 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 94 105 - T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MKLM6_RS21070 195b32b695361581ad3f89dbf6de8d4a 167 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 11 139 6.2E-37 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MKLM6_RS21070 195b32b695361581ad3f89dbf6de8d4a 167 Gene3D G3DSA:3.30.70.560 8 166 3.7E-55 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MKLM6_RS21070 195b32b695361581ad3f89dbf6de8d4a 167 SUPERFAMILY SSF55083 10 161 3.01E-51 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MKLM6_RS21070 195b32b695361581ad3f89dbf6de8d4a 167 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 10 139 1.3E-43 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MKLM6_RS15090 01788416099fdfa51c37f5498e19497f 531 SUPERFAMILY SSF54106 340 383 1.96E-7 T 28-03-2018 IPR018392 LysM domain MKLM6_RS15090 01788416099fdfa51c37f5498e19497f 531 SMART SM00257 415 459 1.6E-13 T 28-03-2018 IPR018392 LysM domain MKLM6_RS15090 01788416099fdfa51c37f5498e19497f 531 SMART SM00257 478 523 4.6E-11 T 28-03-2018 IPR018392 LysM domain MKLM6_RS15090 01788416099fdfa51c37f5498e19497f 531 SMART SM00257 340 383 2.9E-6 T 28-03-2018 IPR018392 LysM domain MKLM6_RS15090 01788416099fdfa51c37f5498e19497f 531 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 129 157 - T 28-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 MKLM6_RS15090 01788416099fdfa51c37f5498e19497f 531 SUPERFAMILY SSF54106 414 458 2.35E-9 T 28-03-2018 IPR018392 LysM domain MKLM6_RS15090 01788416099fdfa51c37f5498e19497f 531 Pfam PF01476 LysM domain 479 522 3.9E-13 T 28-03-2018 IPR018392 LysM domain MKLM6_RS15090 01788416099fdfa51c37f5498e19497f 531 Pfam PF01476 LysM domain 341 383 5.8E-7 T 28-03-2018 IPR018392 LysM domain MKLM6_RS15090 01788416099fdfa51c37f5498e19497f 531 Pfam PF01476 LysM domain 416 458 3.4E-12 T 28-03-2018 IPR018392 LysM domain MKLM6_RS15090 01788416099fdfa51c37f5498e19497f 531 Gene3D G3DSA:1.10.530.10 29 254 2.2E-32 T 28-03-2018 MKLM6_RS15090 01788416099fdfa51c37f5498e19497f 531 Gene3D G3DSA:3.10.350.10 473 531 1.2E-13 T 28-03-2018 MKLM6_RS15090 01788416099fdfa51c37f5498e19497f 531 Gene3D G3DSA:3.10.350.10 338 401 4.9E-9 T 28-03-2018 MKLM6_RS15090 01788416099fdfa51c37f5498e19497f 531 Gene3D G3DSA:3.10.350.10 408 472 1.6E-14 T 28-03-2018 MKLM6_RS15090 01788416099fdfa51c37f5498e19497f 531 Pfam PF01464 Transglycosylase SLT domain 122 219 2.3E-25 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 MKLM6_RS15090 01788416099fdfa51c37f5498e19497f 531 SUPERFAMILY SSF54106 477 522 5.75E-10 T 28-03-2018 IPR018392 LysM domain MKLM6_RS15090 01788416099fdfa51c37f5498e19497f 531 SUPERFAMILY SSF53955 107 260 2.81E-40 T 28-03-2018 IPR023346 Lysozyme-like domain MKLM6_RS20840 24170378a7e87cf1a94397d2bdb08d06 122 SUPERFAMILY SSF52172 3 120 4.55E-35 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS20840 24170378a7e87cf1a94397d2bdb08d06 122 SMART SM00448 3 116 3.8E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS20840 24170378a7e87cf1a94397d2bdb08d06 122 Gene3D G3DSA:3.40.50.2300 1 121 3.3E-35 T 28-03-2018 MKLM6_RS20840 24170378a7e87cf1a94397d2bdb08d06 122 Pfam PF00072 Response regulator receiver domain 5 116 7.9E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS17795 e58a0f37769dac17a5b9303ddb841105 304 SUPERFAMILY SSF82649 2 131 3.14E-42 T 28-03-2018 MKLM6_RS17795 e58a0f37769dac17a5b9303ddb841105 304 SUPERFAMILY SSF117916 214 289 1.13E-20 T 28-03-2018 IPR034904 Fe-S cluster assembly domain MKLM6_RS17795 e58a0f37769dac17a5b9303ddb841105 304 Pfam PF01106 NifU-like domain 223 287 2.3E-20 T 28-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 MKLM6_RS17795 e58a0f37769dac17a5b9303ddb841105 304 Gene3D G3DSA:3.90.1010.10 1 158 1.1E-56 T 28-03-2018 MKLM6_RS17795 e58a0f37769dac17a5b9303ddb841105 304 Gene3D G3DSA:3.30.300.130 218 294 3.0E-20 T 28-03-2018 IPR034904 Fe-S cluster assembly domain MKLM6_RS17795 e58a0f37769dac17a5b9303ddb841105 304 TIGRFAM TIGR02000 NifU_proper: Fe-S cluster assembly protein NifU 1 289 4.2E-139 T 28-03-2018 IPR010238 NIF system FeS cluster assembly, NifU GO:0005506|GO:0016226|GO:0051536 MKLM6_RS17795 e58a0f37769dac17a5b9303ddb841105 304 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 231 290 4.0E-11 T 28-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 MKLM6_RS17795 e58a0f37769dac17a5b9303ddb841105 304 PIRSF PIRSF000375 1 290 1.8E-125 T 28-03-2018 IPR016217 Nitrogen fixation, NifU MKLM6_RS17795 e58a0f37769dac17a5b9303ddb841105 304 Pfam PF01592 NifU-like N terminal domain 4 125 1.8E-49 T 28-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 MKLM6_RS17795 e58a0f37769dac17a5b9303ddb841105 304 Pfam PF04324 BFD-like [2Fe-2S] binding domain 135 184 3.2E-16 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain MKLM6_RS15495 6a7d753aa89ae08046e5a9d22c50791e 126 SUPERFAMILY SSF46458 7 125 3.14E-38 T 28-03-2018 IPR009050 Globin-like MKLM6_RS15495 6a7d753aa89ae08046e5a9d22c50791e 126 PIRSF PIRSF002030 1 126 2.9E-46 T 28-03-2018 IPR016339 Truncated hemoglobin, group 1 MKLM6_RS15495 6a7d753aa89ae08046e5a9d22c50791e 126 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 54 74 - T 28-03-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 MKLM6_RS15495 6a7d753aa89ae08046e5a9d22c50791e 126 Gene3D G3DSA:1.10.490.10 6 126 8.6E-40 T 28-03-2018 MKLM6_RS15495 6a7d753aa89ae08046e5a9d22c50791e 126 Pfam PF01152 Bacterial-like globin 7 119 3.3E-19 T 28-03-2018 IPR001486 Truncated hemoglobin GO:0019825 MKLM6_RS15955 d91eedbc1ae9879c3ab39889404bedb4 303 SUPERFAMILY SSF103481 51 153 1.44E-12 T 28-03-2018 MKLM6_RS15955 d91eedbc1ae9879c3ab39889404bedb4 303 SUPERFAMILY SSF103481 207 302 3.53E-11 T 28-03-2018 MKLM6_RS15955 d91eedbc1ae9879c3ab39889404bedb4 303 Pfam PF00892 EamA-like transporter family 17 153 2.2E-19 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MKLM6_RS15955 d91eedbc1ae9879c3ab39889404bedb4 303 Pfam PF00892 EamA-like transporter family 166 301 3.6E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MKLM6_RS18800 5f62decfd8535f567495ebfce536a1b5 247 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 5 224 8.3E-57 T 28-03-2018 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 MKLM6_RS18800 5f62decfd8535f567495ebfce536a1b5 247 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 172 243 2.2E-20 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain MKLM6_RS18800 5f62decfd8535f567495ebfce536a1b5 247 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 121 8.5E-34 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G MKLM6_RS18800 5f62decfd8535f567495ebfce536a1b5 247 SUPERFAMILY SSF117143 78 205 6.02E-18 T 28-03-2018 MKLM6_RS18800 5f62decfd8535f567495ebfce536a1b5 247 Pfam PF00460 Flagella basal body rod protein 5 35 2.9E-5 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 MKLM6_RS18800 5f62decfd8535f567495ebfce536a1b5 247 Gene3D G3DSA:2.60.120.10 10 144 0.0015 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS01095 bd7ade02d6feeca686f997a4fb06ac4c 225 SUPERFAMILY SSF51161 13 201 1.52E-41 T 28-03-2018 IPR011004 Trimeric LpxA-like MKLM6_RS01095 bd7ade02d6feeca686f997a4fb06ac4c 225 Gene3D G3DSA:2.160.10.10 3 216 9.0E-45 T 28-03-2018 MKLM6_RS01095 bd7ade02d6feeca686f997a4fb06ac4c 225 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 124 152 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MKLM6_RS01095 bd7ade02d6feeca686f997a4fb06ac4c 225 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 115 150 1.2E-9 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS00765 f263fde4b679faa7659a403ce8587bae 155 SMART SM00116 88 135 2.8E-14 T 28-03-2018 IPR000644 CBS domain MKLM6_RS00765 f263fde4b679faa7659a403ce8587bae 155 SMART SM00116 10 57 7.2E-9 T 28-03-2018 IPR000644 CBS domain MKLM6_RS00765 f263fde4b679faa7659a403ce8587bae 155 Pfam PF00571 CBS domain 3 56 1.1E-12 T 28-03-2018 IPR000644 CBS domain MKLM6_RS00765 f263fde4b679faa7659a403ce8587bae 155 Pfam PF00571 CBS domain 83 135 1.0E-14 T 28-03-2018 IPR000644 CBS domain MKLM6_RS00765 f263fde4b679faa7659a403ce8587bae 155 SUPERFAMILY SSF54631 1 135 6.32E-34 T 28-03-2018 MKLM6_RS00765 f263fde4b679faa7659a403ce8587bae 155 Gene3D G3DSA:3.10.580.10 1 68 1.4E-13 T 28-03-2018 MKLM6_RS00765 f263fde4b679faa7659a403ce8587bae 155 Gene3D G3DSA:3.10.580.10 69 150 6.3E-16 T 28-03-2018 MKLM6_RS03515 c926fe3100cbe4ee854da34a135eb190 211 Gene3D G3DSA:3.30.1050.10 10 122 1.2E-8 T 28-03-2018 IPR003033 SCP2 sterol-binding domain MKLM6_RS03515 c926fe3100cbe4ee854da34a135eb190 211 SUPERFAMILY SSF55718 16 121 5.89E-9 T 28-03-2018 IPR003033 SCP2 sterol-binding domain MKLM6_RS03515 c926fe3100cbe4ee854da34a135eb190 211 Pfam PF02036 SCP-2 sterol transfer family 19 115 1.7E-14 T 28-03-2018 IPR003033 SCP2 sterol-binding domain MKLM6_RS01475 f3e3171b6ff93b5a045a20280e9cbf3b 432 Pfam PF05193 Peptidase M16 inactive domain 188 363 1.7E-37 T 28-03-2018 IPR007863 Peptidase M16, C-terminal MKLM6_RS01475 f3e3171b6ff93b5a045a20280e9cbf3b 432 Gene3D G3DSA:3.30.830.10 17 238 1.6E-44 T 28-03-2018 MKLM6_RS01475 f3e3171b6ff93b5a045a20280e9cbf3b 432 Gene3D G3DSA:3.30.830.10 243 432 3.1E-38 T 28-03-2018 MKLM6_RS01475 f3e3171b6ff93b5a045a20280e9cbf3b 432 SUPERFAMILY SSF63411 245 431 1.83E-46 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MKLM6_RS01475 f3e3171b6ff93b5a045a20280e9cbf3b 432 Pfam PF00675 Insulinase (Peptidase family M16) 34 172 5.0E-11 T 28-03-2018 IPR011765 Peptidase M16, N-terminal MKLM6_RS01475 f3e3171b6ff93b5a045a20280e9cbf3b 432 SUPERFAMILY SSF63411 20 227 3.17E-48 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MKLM6_RS09195 b21ca67ca40515dceccf55d8f80f78e0 540 Gene3D G3DSA:3.30.750.24 447 528 7.2E-7 T 28-03-2018 IPR002645 STAS domain MKLM6_RS09195 b21ca67ca40515dceccf55d8f80f78e0 540 Pfam PF00916 Sulfate permease family 22 405 1.6E-55 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MKLM6_RS09195 b21ca67ca40515dceccf55d8f80f78e0 540 SUPERFAMILY SSF52091 455 523 2.55E-6 T 28-03-2018 IPR002645 STAS domain MKLM6_RS03370 470572d494667d0fdddb9904e0cb45de 364 SUPERFAMILY SSF81345 18 358 7.19E-78 T 28-03-2018 IPR029022 ABC transporter, BtuC-like MKLM6_RS03370 470572d494667d0fdddb9904e0cb45de 364 Gene3D G3DSA:1.10.3470.10 19 363 2.4E-69 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like MKLM6_RS03370 470572d494667d0fdddb9904e0cb45de 364 Pfam PF01032 FecCD transport family 32 358 6.6E-88 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 MKLM6_RS09935 96e1510336d07b9769b741f1f5db3aaa 375 Gene3D G3DSA:2.40.50.100 186 359 4.9E-4 T 28-03-2018 MKLM6_RS09935 96e1510336d07b9769b741f1f5db3aaa 375 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 70 294 1.0E-27 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MKLM6_RS09935 96e1510336d07b9769b741f1f5db3aaa 375 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 61 366 2.2E-41 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MKLM6_RS09935 96e1510336d07b9769b741f1f5db3aaa 375 Gene3D G3DSA:2.40.50.100 85 182 4.7E-10 T 28-03-2018 MKLM6_RS09935 96e1510336d07b9769b741f1f5db3aaa 375 SUPERFAMILY SSF111369 73 299 1.03E-12 T 28-03-2018 MKLM6_RS06285 7465472fc010f21f6902a14fb9e083a0 77 Gene3D G3DSA:1.10.1200.10 1 77 4.9E-27 T 28-03-2018 MKLM6_RS06285 7465472fc010f21f6902a14fb9e083a0 77 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 75 4.3E-34 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 MKLM6_RS06285 7465472fc010f21f6902a14fb9e083a0 77 Hamap MF_01217 Acyl carrier protein [acpP]. 3 76 21.849 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 MKLM6_RS06285 7465472fc010f21f6902a14fb9e083a0 77 SUPERFAMILY SSF47336 2 76 1.01E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS06285 7465472fc010f21f6902a14fb9e083a0 77 ProSitePatterns PS00012 Phosphopantetheine attachment site. 31 46 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site MKLM6_RS06285 7465472fc010f21f6902a14fb9e083a0 77 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 40 76 0.007 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 MKLM6_RS06285 7465472fc010f21f6902a14fb9e083a0 77 Pfam PF00550 Phosphopantetheine attachment site 6 72 4.8E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS06290 c1f10b3053f3ae48dbcd4c0d62e6e7a0 414 SUPERFAMILY SSF53901 215 413 2.1E-75 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS06290 c1f10b3053f3ae48dbcd4c0d62e6e7a0 414 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 248 1.9E-57 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MKLM6_RS06290 c1f10b3053f3ae48dbcd4c0d62e6e7a0 414 Gene3D G3DSA:3.40.47.10 264 414 9.2E-55 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS06290 c1f10b3053f3ae48dbcd4c0d62e6e7a0 414 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 256 370 5.8E-39 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MKLM6_RS06290 c1f10b3053f3ae48dbcd4c0d62e6e7a0 414 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 411 1.7E-198 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 MKLM6_RS06290 c1f10b3053f3ae48dbcd4c0d62e6e7a0 414 SUPERFAMILY SSF53901 4 253 1.69E-76 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS06290 c1f10b3053f3ae48dbcd4c0d62e6e7a0 414 SMART SM00825 Beta-ketoacyl synthase 6 414 7.1E-18 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MKLM6_RS06290 c1f10b3053f3ae48dbcd4c0d62e6e7a0 414 Gene3D G3DSA:3.40.47.10 6 261 2.6E-79 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MKLM6_RS06290 c1f10b3053f3ae48dbcd4c0d62e6e7a0 414 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site MKLM6_RS06290 c1f10b3053f3ae48dbcd4c0d62e6e7a0 414 PIRSF PIRSF000447 1 414 5.1E-189 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 MKLM6_RS04970 82dd361d4447859ac9356f59a43e791e 71 Gene3D G3DSA:1.10.287.660 3 68 5.7E-23 T 28-03-2018 IPR029012 Helix hairpin bin domain MKLM6_RS04970 82dd361d4447859ac9356f59a43e791e 71 PIRSF PIRSF037676 1 70 9.2E-19 T 28-03-2018 IPR007774 Putative nitrogen fixation protein MKLM6_RS04970 82dd361d4447859ac9356f59a43e791e 71 Pfam PF05082 Rop-like 4 66 1.7E-24 T 28-03-2018 IPR007774 Putative nitrogen fixation protein MKLM6_RS12955 20dc673805d807f0de6196b2ebfa1505 434 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 150 419 1.8E-74 T 28-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 MKLM6_RS12955 20dc673805d807f0de6196b2ebfa1505 434 SUPERFAMILY SSF101960 28 427 7.59E-98 T 28-03-2018 MKLM6_RS12955 20dc673805d807f0de6196b2ebfa1505 434 Pfam PF01458 Uncharacterized protein family (UPF0051) 184 404 3.8E-67 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 MKLM6_RS05675 a0202917aad14d51ca49275c82472320 155 SUPERFAMILY SSF47240 1 155 9.35E-48 T 28-03-2018 IPR009078 Ferritin-like superfamily MKLM6_RS05675 a0202917aad14d51ca49275c82472320 155 Gene3D G3DSA:1.20.1260.10 1 78 1.3E-17 T 28-03-2018 IPR012347 Ferritin-related MKLM6_RS05675 a0202917aad14d51ca49275c82472320 155 Pfam PF00210 Ferritin-like domain 8 144 1.4E-37 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MKLM6_RS05675 a0202917aad14d51ca49275c82472320 155 PIRSF PIRSF002560 1 155 1.3E-64 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MKLM6_RS05675 a0202917aad14d51ca49275c82472320 155 TIGRFAM TIGR00754 bfr: bacterioferritin 1 155 3.1E-54 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MKLM6_RS05675 a0202917aad14d51ca49275c82472320 155 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MKLM6_RS05675 a0202917aad14d51ca49275c82472320 155 Gene3D G3DSA:1.20.5.420 85 140 3.0E-18 T 28-03-2018 MKLM6_RS05675 a0202917aad14d51ca49275c82472320 155 PRINTS PR00601 Bacterioferritin signature 129 150 1.7E-51 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MKLM6_RS05675 a0202917aad14d51ca49275c82472320 155 PRINTS PR00601 Bacterioferritin signature 3 22 1.7E-51 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MKLM6_RS05675 a0202917aad14d51ca49275c82472320 155 PRINTS PR00601 Bacterioferritin signature 65 85 1.7E-51 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MKLM6_RS05675 a0202917aad14d51ca49275c82472320 155 PRINTS PR00601 Bacterioferritin signature 23 43 1.7E-51 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MKLM6_RS05675 a0202917aad14d51ca49275c82472320 155 PRINTS PR00601 Bacterioferritin signature 44 64 1.7E-51 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MKLM6_RS05675 a0202917aad14d51ca49275c82472320 155 PRINTS PR00601 Bacterioferritin signature 107 127 1.7E-51 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MKLM6_RS05675 a0202917aad14d51ca49275c82472320 155 PRINTS PR00601 Bacterioferritin signature 86 106 1.7E-51 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MKLM6_RS02710 26e67d3e9b7548b1fe756af38bdb8450 327 SUPERFAMILY SSF101801 250 322 8.37E-14 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) MKLM6_RS02710 26e67d3e9b7548b1fe756af38bdb8450 327 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 5 322 6.7E-111 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MKLM6_RS02710 26e67d3e9b7548b1fe756af38bdb8450 327 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 254 321 4.4E-17 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) MKLM6_RS02710 26e67d3e9b7548b1fe756af38bdb8450 327 Pfam PF02154 Flagellar motor switch protein FliM 41 233 3.6E-76 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MKLM6_RS02710 26e67d3e9b7548b1fe756af38bdb8450 327 PRINTS PR00955 Flagellar motor switch protein FliM signature 117 136 7.5E-24 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MKLM6_RS02710 26e67d3e9b7548b1fe756af38bdb8450 327 PRINTS PR00955 Flagellar motor switch protein FliM signature 4 17 7.5E-24 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MKLM6_RS02710 26e67d3e9b7548b1fe756af38bdb8450 327 PRINTS PR00955 Flagellar motor switch protein FliM signature 215 233 7.5E-24 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MKLM6_RS02710 26e67d3e9b7548b1fe756af38bdb8450 327 PRINTS PR00955 Flagellar motor switch protein FliM signature 92 108 7.5E-24 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MKLM6_RS02710 26e67d3e9b7548b1fe756af38bdb8450 327 Gene3D G3DSA:2.30.330.10 241 326 1.7E-14 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) MKLM6_RS02710 26e67d3e9b7548b1fe756af38bdb8450 327 PIRSF PIRSF002888 3 326 2.3E-97 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MKLM6_RS02710 26e67d3e9b7548b1fe756af38bdb8450 327 Gene3D G3DSA:3.40.1550.10 49 238 7.4E-41 T 28-03-2018 IPR028976 CheC-like domain MKLM6_RS02710 26e67d3e9b7548b1fe756af38bdb8450 327 SUPERFAMILY SSF103039 58 234 2.22E-20 T 28-03-2018 IPR028976 CheC-like domain MKLM6_RS02710 26e67d3e9b7548b1fe756af38bdb8450 327 SUPERFAMILY SSF103039 7 15 2.22E-20 T 28-03-2018 IPR028976 CheC-like domain MKLM6_RS16380 4c308a02b3a7faf2623729fd42d256ca 278 TIGRFAM TIGR04557 fuse_rel_SoxYZ: quinoprotein dehydrogenase-associated SoxYZ-like carrier 30 252 1.2E-82 T 28-03-2018 IPR030831 Quinoprotein dehydrogenase-associated SoxYZ-like carrier MKLM6_RS16380 4c308a02b3a7faf2623729fd42d256ca 278 SUPERFAMILY SSF81296 161 252 8.82E-22 T 28-03-2018 IPR014756 Immunoglobulin E-set MKLM6_RS16380 4c308a02b3a7faf2623729fd42d256ca 278 Gene3D G3DSA:2.60.40.730 37 143 2.1E-15 T 28-03-2018 MKLM6_RS16380 4c308a02b3a7faf2623729fd42d256ca 278 Gene3D G3DSA:2.60.40.10 164 263 4.7E-24 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS16380 4c308a02b3a7faf2623729fd42d256ca 278 Pfam PF08770 Sulphur oxidation protein SoxZ 172 258 1.4E-23 T 28-03-2018 IPR014880 Sulphur oxidation protein SoxZ MKLM6_RS16380 4c308a02b3a7faf2623729fd42d256ca 278 Pfam PF13501 Sulfur oxidation protein SoxY 36 146 2.1E-36 T 28-03-2018 IPR032711 Ig-like SoxY domain MKLM6_RS03005 93e5419d6d85f5afa2db81f572645564 77 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 19.696 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS03005 93e5419d6d85f5afa2db81f572645564 77 Pfam PF01165 Ribosomal protein S21 3 56 1.1E-20 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS03005 93e5419d6d85f5afa2db81f572645564 77 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 4.5E-16 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS03005 93e5419d6d85f5afa2db81f572645564 77 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 4.5E-16 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS03005 93e5419d6d85f5afa2db81f572645564 77 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 4.5E-16 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS03005 93e5419d6d85f5afa2db81f572645564 77 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 4.5E-16 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS03005 93e5419d6d85f5afa2db81f572645564 77 Gene3D G3DSA:1.20.5.1150 16 52 1.7E-17 T 28-03-2018 MKLM6_RS03005 93e5419d6d85f5afa2db81f572645564 77 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 14 56 1.0E-14 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS03005 93e5419d6d85f5afa2db81f572645564 77 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 2.6E-23 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS03005 93e5419d6d85f5afa2db81f572645564 77 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 28-03-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS06745 0130cfee7774a23f717108c6055ee3e8 88 SUPERFAMILY SSF143011 1 83 3.53E-15 T 28-03-2018 IPR035095 Toxin RelE-like domain MKLM6_RS06745 0130cfee7774a23f717108c6055ee3e8 88 Gene3D G3DSA:3.30.2310.20 1 88 6.8E-16 T 28-03-2018 MKLM6_RS06745 0130cfee7774a23f717108c6055ee3e8 88 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 3 84 9.4E-8 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MKLM6_RS05560 90c71cf9f8dd963316ce45dc92c42b1a 52 Pfam PF03466 LysR substrate binding domain 1 45 4.7E-7 T 28-03-2018 IPR005119 LysR, substrate-binding MKLM6_RS05560 90c71cf9f8dd963316ce45dc92c42b1a 52 Gene3D G3DSA:3.40.190.10 1 51 1.0E-4 T 28-03-2018 MKLM6_RS05560 90c71cf9f8dd963316ce45dc92c42b1a 52 SUPERFAMILY SSF53850 1 48 1.43E-7 T 28-03-2018 MKLM6_RS01110 a16c0036d9074580e25dea07e834b61d 473 Gene3D G3DSA:3.40.50.720 142 271 9.9E-17 T 28-03-2018 MKLM6_RS01110 a16c0036d9074580e25dea07e834b61d 473 TIGRFAM TIGR03023 WcaJ_sugtrans: undecaprenyl-phosphate glucose phosphotransferase 25 473 2.1E-160 T 28-03-2018 IPR017473 Undecaprenyl-phosphate glucose phosphotransferase, WcaJ MetaCyc: PWY-6655|MetaCyc: PWY-6658 MKLM6_RS01110 a16c0036d9074580e25dea07e834b61d 473 Pfam PF02397 Bacterial sugar transferase 283 465 6.9E-59 T 28-03-2018 IPR003362 Bacterial sugar transferase MKLM6_RS01110 a16c0036d9074580e25dea07e834b61d 473 SUPERFAMILY SSF51735 146 273 5.91E-6 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS01110 a16c0036d9074580e25dea07e834b61d 473 Pfam PF13727 CoA-binding domain 67 246 2.6E-32 T 28-03-2018 MKLM6_RS01110 a16c0036d9074580e25dea07e834b61d 473 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 24 473 3.1E-141 T 28-03-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase MKLM6_RS11045 00349e493710ae14cb5e93be811514ee 192 SMART SM00947 25 183 2.3E-31 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MKLM6_RS11045 00349e493710ae14cb5e93be811514ee 192 Gene3D G3DSA:3.40.1050.10 2 191 3.1E-36 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MKLM6_RS11045 00349e493710ae14cb5e93be811514ee 192 Pfam PF00484 Carbonic anhydrase 33 179 7.3E-12 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MKLM6_RS11045 00349e493710ae14cb5e93be811514ee 192 SUPERFAMILY SSF53056 6 182 7.06E-39 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MKLM6_RS06830 1194e70654790d643af83afd2f1022ac 309 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 251 265 9.6E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS06830 1194e70654790d643af83afd2f1022ac 309 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 281 293 9.6E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS06830 1194e70654790d643af83afd2f1022ac 309 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 265 281 9.6E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS06830 1194e70654790d643af83afd2f1022ac 309 Gene3D G3DSA:1.10.10.10 145 309 3.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS06830 1194e70654790d643af83afd2f1022ac 309 SMART SM00448 9 122 5.3E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS06830 1194e70654790d643af83afd2f1022ac 309 SUPERFAMILY SSF46894 242 307 1.6E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MKLM6_RS06830 1194e70654790d643af83afd2f1022ac 309 SMART SM00421 248 305 8.9E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS06830 1194e70654790d643af83afd2f1022ac 309 Gene3D G3DSA:3.40.50.2300 2 143 7.9E-34 T 28-03-2018 MKLM6_RS06830 1194e70654790d643af83afd2f1022ac 309 Pfam PF00196 Bacterial regulatory proteins, luxR family 251 304 3.6E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS06830 1194e70654790d643af83afd2f1022ac 309 SUPERFAMILY SSF52172 6 138 3.13E-39 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS06830 1194e70654790d643af83afd2f1022ac 309 Pfam PF00072 Response regulator receiver domain 11 122 1.1E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS03905 25099c042eac05189c817c74c354727b 187 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 84 184 2.5E-42 T 28-03-2018 IPR014169 Peptidoglycan-associated lipoprotein GO:0009279 MKLM6_RS03905 25099c042eac05189c817c74c354727b 187 Gene3D G3DSA:3.30.1330.60 69 187 2.6E-31 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS03905 25099c042eac05189c817c74c354727b 187 ProSitePatterns PS01068 OmpA-like domain. 118 162 - T 28-03-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 MKLM6_RS03905 25099c042eac05189c817c74c354727b 187 Pfam PF00691 OmpA family 85 175 2.4E-19 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS03905 25099c042eac05189c817c74c354727b 187 PRINTS PR01021 OMPA domain signature 86 108 3.3E-11 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MKLM6_RS03905 25099c042eac05189c817c74c354727b 187 PRINTS PR01021 OMPA domain signature 116 131 3.3E-11 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MKLM6_RS03905 25099c042eac05189c817c74c354727b 187 PRINTS PR01021 OMPA domain signature 131 147 3.3E-11 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MKLM6_RS03905 25099c042eac05189c817c74c354727b 187 SUPERFAMILY SSF103088 84 184 2.62E-32 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS10250 905ab86432730118e9125519fcfaa645 202 Gene3D G3DSA:1.10.10.10 1 70 1.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS10250 905ab86432730118e9125519fcfaa645 202 Pfam PF00717 Peptidase S24-like 115 174 1.7E-10 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MKLM6_RS10250 905ab86432730118e9125519fcfaa645 202 Pfam PF01726 LexA DNA binding domain 1 65 7.6E-24 T 28-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 MKLM6_RS10250 905ab86432730118e9125519fcfaa645 202 Hamap MF_00015 LexA repressor [lexA]. 3 200 31.266 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 MKLM6_RS10250 905ab86432730118e9125519fcfaa645 202 Gene3D G3DSA:2.10.109.10 81 200 3.5E-22 T 28-03-2018 MKLM6_RS10250 905ab86432730118e9125519fcfaa645 202 SUPERFAMILY SSF46785 3 70 3.27E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS10250 905ab86432730118e9125519fcfaa645 202 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 151 163 5.8E-11 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MKLM6_RS10250 905ab86432730118e9125519fcfaa645 202 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 112 122 5.8E-11 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MKLM6_RS10250 905ab86432730118e9125519fcfaa645 202 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 123 134 5.8E-11 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MKLM6_RS10250 905ab86432730118e9125519fcfaa645 202 SUPERFAMILY SSF51306 77 198 6.1E-34 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MKLM6_RS10250 905ab86432730118e9125519fcfaa645 202 TIGRFAM TIGR00498 lexA: repressor LexA 1 200 6.6E-67 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 MKLM6_RS18730 32d7328ae48bc47a4028f3f4380c331a 541 Pfam PF12161 HsdM N-terminal domain 16 170 4.8E-25 T 28-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain MKLM6_RS18730 32d7328ae48bc47a4028f3f4380c331a 541 SUPERFAMILY SSF53335 15 53 3.0E-109 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS18730 32d7328ae48bc47a4028f3f4380c331a 541 SUPERFAMILY SSF53335 100 538 3.0E-109 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS18730 32d7328ae48bc47a4028f3f4380c331a 541 Gene3D G3DSA:3.40.50.150 203 497 6.4E-50 T 28-03-2018 MKLM6_RS18730 32d7328ae48bc47a4028f3f4380c331a 541 Pfam PF02384 N-6 DNA Methylase 182 502 2.1E-87 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 MKLM6_RS18730 32d7328ae48bc47a4028f3f4380c331a 541 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 347 371 9.8E-13 T 28-03-2018 MKLM6_RS18730 32d7328ae48bc47a4028f3f4380c331a 541 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 205 221 9.8E-13 T 28-03-2018 MKLM6_RS18730 32d7328ae48bc47a4028f3f4380c331a 541 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 229 243 9.8E-13 T 28-03-2018 MKLM6_RS18730 32d7328ae48bc47a4028f3f4380c331a 541 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 310 322 9.8E-13 T 28-03-2018 MKLM6_RS21105 0c52d7e87e32e66a3bd0b566e4bcf053 494 SUPERFAMILY SSF52949 1 181 1.24E-38 T 28-03-2018 MKLM6_RS21105 0c52d7e87e32e66a3bd0b566e4bcf053 494 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 3 493 36.946 T 28-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 MKLM6_RS21105 0c52d7e87e32e66a3bd0b566e4bcf053 494 Gene3D G3DSA:3.40.220.10 1 159 4.6E-33 T 28-03-2018 MKLM6_RS21105 0c52d7e87e32e66a3bd0b566e4bcf053 494 Gene3D G3DSA:3.40.630.10 167 494 4.6E-130 T 28-03-2018 MKLM6_RS21105 0c52d7e87e32e66a3bd0b566e4bcf053 494 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 183 483 2.3E-120 T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MKLM6_RS21105 0c52d7e87e32e66a3bd0b566e4bcf053 494 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 345 352 - T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MKLM6_RS21105 0c52d7e87e32e66a3bd0b566e4bcf053 494 PRINTS PR00481 Cytosol aminopeptidase signature 369 384 8.5E-52 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MKLM6_RS21105 0c52d7e87e32e66a3bd0b566e4bcf053 494 PRINTS PR00481 Cytosol aminopeptidase signature 319 340 8.5E-52 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MKLM6_RS21105 0c52d7e87e32e66a3bd0b566e4bcf053 494 PRINTS PR00481 Cytosol aminopeptidase signature 282 303 8.5E-52 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MKLM6_RS21105 0c52d7e87e32e66a3bd0b566e4bcf053 494 PRINTS PR00481 Cytosol aminopeptidase signature 260 277 8.5E-52 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MKLM6_RS21105 0c52d7e87e32e66a3bd0b566e4bcf053 494 PRINTS PR00481 Cytosol aminopeptidase signature 341 361 8.5E-52 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MKLM6_RS21105 0c52d7e87e32e66a3bd0b566e4bcf053 494 SUPERFAMILY SSF53187 177 491 1.48E-118 T 28-03-2018 MKLM6_RS21105 0c52d7e87e32e66a3bd0b566e4bcf053 494 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 20 145 3.5E-28 T 28-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MKLM6_RS06095 8af9f25ff6d4c0c7e293645a35130601 272 Gene3D G3DSA:3.40.50.1820 21 270 1.7E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS06095 8af9f25ff6d4c0c7e293645a35130601 272 Pfam PF00561 alpha/beta hydrolase fold 115 186 1.6E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS06095 8af9f25ff6d4c0c7e293645a35130601 272 SUPERFAMILY SSF53474 35 51 5.76E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS06095 8af9f25ff6d4c0c7e293645a35130601 272 SUPERFAMILY SSF53474 114 268 5.76E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS18375 53942e988969d1598fe684e448d49938 101 Gene3D G3DSA:4.10.830.10 1 101 2.5E-34 T 28-03-2018 MKLM6_RS18375 53942e988969d1598fe684e448d49938 101 SUPERFAMILY SSF57716 2 101 1.66E-36 T 28-03-2018 MKLM6_RS18375 53942e988969d1598fe684e448d49938 101 ProSitePatterns PS00527 Ribosomal protein S14 signature. 63 85 - T 28-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18375 53942e988969d1598fe684e448d49938 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 27.236 T 28-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid MKLM6_RS18375 53942e988969d1598fe684e448d49938 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 9.9E-25 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS03420 ddf5105587ba56250e68172a5faf29e0 259 SUPERFAMILY SSF74653 175 255 3.92E-23 T 28-03-2018 MKLM6_RS03420 ddf5105587ba56250e68172a5faf29e0 259 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 181 257 5.0E-22 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 MKLM6_RS03420 ddf5105587ba56250e68172a5faf29e0 259 Gene3D G3DSA:3.30.1150.10 72 259 8.1E-20 T 28-03-2018 MKLM6_RS03420 ddf5105587ba56250e68172a5faf29e0 259 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 179 257 1.0E-22 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 MKLM6_RS03420 ddf5105587ba56250e68172a5faf29e0 259 PRINTS PR01217 Proline rich extensin signature 78 99 8.7E-9 T 28-03-2018 MKLM6_RS03420 ddf5105587ba56250e68172a5faf29e0 259 PRINTS PR01217 Proline rich extensin signature 101 117 8.7E-9 T 28-03-2018 MKLM6_RS03420 ddf5105587ba56250e68172a5faf29e0 259 PRINTS PR01217 Proline rich extensin signature 172 184 8.7E-9 T 28-03-2018 MKLM6_RS03420 ddf5105587ba56250e68172a5faf29e0 259 PRINTS PR01217 Proline rich extensin signature 132 157 8.7E-9 T 28-03-2018 MKLM6_RS12715 090fab3a70c2188d122e554aaf11dabc 63 Gene3D G3DSA:2.20.25.10 8 63 2.6E-23 T 28-03-2018 MKLM6_RS12715 090fab3a70c2188d122e554aaf11dabc 63 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 1 54 29.203 T 28-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 MKLM6_RS12715 090fab3a70c2188d122e554aaf11dabc 63 Pfam PF03966 Trm112p-like protein 2 41 2.3E-11 T 28-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 MKLM6_RS12715 090fab3a70c2188d122e554aaf11dabc 63 SUPERFAMILY SSF158997 1 54 3.01E-22 T 28-03-2018 MKLM6_RS08700 612f7bee8c066be047f0daba1782eb5d 181 Pfam PF04442 Cytochrome c oxidase assembly protein CtaG/Cox11 31 174 4.9E-37 T 28-03-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08700 612f7bee8c066be047f0daba1782eb5d 181 Gene3D G3DSA:2.60.370.10 58 179 1.9E-31 T 28-03-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08700 612f7bee8c066be047f0daba1782eb5d 181 PIRSF PIRSF005413 1 181 2.6E-48 T 28-03-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08700 612f7bee8c066be047f0daba1782eb5d 181 SUPERFAMILY SSF110111 57 178 2.48E-32 T 28-03-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS19080 a3545cfd59ffd863cece4ab8a5afaf64 379 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 1 379 2.4E-120 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MKLM6_RS19080 a3545cfd59ffd863cece4ab8a5afaf64 379 PIRSF PIRSF000267 2 378 3.6E-109 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MKLM6_RS19080 a3545cfd59ffd863cece4ab8a5afaf64 379 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 8 361 1.5E-94 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MKLM6_RS08465 b0b31d1fcfc0b6ee8c8ce710f476e79c 199 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 30 189 8.4E-39 T 28-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component MKLM6_RS08465 b0b31d1fcfc0b6ee8c8ce710f476e79c 199 SUPERFAMILY SSF159594 28 195 2.2E-30 T 28-03-2018 MKLM6_RS08465 b0b31d1fcfc0b6ee8c8ce710f476e79c 199 Gene3D G3DSA:3.40.50.10610 18 199 8.5E-41 T 28-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component MKLM6_RS18770 92ddac6edc5987ad556b5142c44f68b1 310 SMART SM00260 17 153 1.1E-25 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS18770 92ddac6edc5987ad556b5142c44f68b1 310 SUPERFAMILY SSF52172 177 304 2.42E-24 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS18770 92ddac6edc5987ad556b5142c44f68b1 310 PIRSF PIRSF002867 1 306 1.8E-105 T 28-03-2018 IPR024181 Chemotaxis response regulator CheV MKLM6_RS18770 92ddac6edc5987ad556b5142c44f68b1 310 Pfam PF01584 CheW-like domain 21 155 3.0E-35 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS18770 92ddac6edc5987ad556b5142c44f68b1 310 Pfam PF00072 Response regulator receiver domain 179 298 1.7E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS18770 92ddac6edc5987ad556b5142c44f68b1 310 SMART SM00448 177 298 1.4E-13 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS18770 92ddac6edc5987ad556b5142c44f68b1 310 Gene3D G3DSA:2.30.30.40 105 147 1.1E-11 T 28-03-2018 MKLM6_RS18770 92ddac6edc5987ad556b5142c44f68b1 310 Gene3D G3DSA:2.40.50.180 39 104 8.0E-16 T 28-03-2018 MKLM6_RS18770 92ddac6edc5987ad556b5142c44f68b1 310 Gene3D G3DSA:3.40.50.2300 168 310 1.6E-23 T 28-03-2018 MKLM6_RS18770 92ddac6edc5987ad556b5142c44f68b1 310 SUPERFAMILY SSF50341 17 156 7.72E-35 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS10055 c11bfdbdd5a456ca685ae09a8e291d57 594 SUPERFAMILY SSF56425 239 357 1.94E-41 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MKLM6_RS10055 c11bfdbdd5a456ca685ae09a8e291d57 594 Pfam PF02910 Fumarate reductase flavoprotein C-term 462 594 5.0E-43 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MKLM6_RS10055 c11bfdbdd5a456ca685ae09a8e291d57 594 SUPERFAMILY SSF46977 453 594 7.33E-50 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MKLM6_RS10055 c11bfdbdd5a456ca685ae09a8e291d57 594 Gene3D G3DSA:1.20.58.100 432 543 9.3E-35 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MKLM6_RS10055 c11bfdbdd5a456ca685ae09a8e291d57 594 Pfam PF00890 FAD binding domain 13 407 5.5E-121 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MKLM6_RS10055 c11bfdbdd5a456ca685ae09a8e291d57 594 Gene3D G3DSA:4.10.80.40 544 594 2.2E-23 T 28-03-2018 MKLM6_RS10055 c11bfdbdd5a456ca685ae09a8e291d57 594 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 13 594 3.8E-242 T 28-03-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MKLM6_RS10055 c11bfdbdd5a456ca685ae09a8e291d57 594 PIRSF PIRSF000171 2 585 1.7E-37 T 28-03-2018 MKLM6_RS10055 c11bfdbdd5a456ca685ae09a8e291d57 594 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 10 594 3.6E-289 T 28-03-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MKLM6_RS10055 c11bfdbdd5a456ca685ae09a8e291d57 594 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 47 56 - T 28-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MKLM6_RS10055 c11bfdbdd5a456ca685ae09a8e291d57 594 SUPERFAMILY SSF51905 6 262 1.8E-74 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS10055 c11bfdbdd5a456ca685ae09a8e291d57 594 SUPERFAMILY SSF51905 361 428 1.8E-74 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS10055 c11bfdbdd5a456ca685ae09a8e291d57 594 Gene3D G3DSA:3.50.50.60 301 422 5.8E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS10055 c11bfdbdd5a456ca685ae09a8e291d57 594 Gene3D G3DSA:3.50.50.60 2 300 4.6E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS13685 28b801b428a2bd953eff153e42614517 403 Gene3D G3DSA:3.40.50.620 2 164 7.7E-29 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS13685 28b801b428a2bd953eff153e42614517 403 Pfam PF00764 Arginosuccinate synthase 8 398 1.7E-156 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MKLM6_RS13685 28b801b428a2bd953eff153e42614517 403 Hamap MF_00005 Argininosuccinate synthase [argG]. 4 403 51.766 T 28-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MKLM6_RS13685 28b801b428a2bd953eff153e42614517 403 Gene3D G3DSA:3.90.1260.10 165 357 2.2E-96 T 28-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MKLM6_RS13685 28b801b428a2bd953eff153e42614517 403 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 118 129 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MKLM6_RS13685 28b801b428a2bd953eff153e42614517 403 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 10 18 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MKLM6_RS13685 28b801b428a2bd953eff153e42614517 403 TIGRFAM TIGR00032 argG: argininosuccinate synthase 6 401 6.1E-143 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MKLM6_RS13685 28b801b428a2bd953eff153e42614517 403 SUPERFAMILY SSF69864 177 401 2.88E-94 T 28-03-2018 MKLM6_RS13685 28b801b428a2bd953eff153e42614517 403 Gene3D G3DSA:1.20.5.470 368 401 2.8E-16 T 28-03-2018 MKLM6_RS13685 28b801b428a2bd953eff153e42614517 403 SUPERFAMILY SSF52402 5 208 5.82E-50 T 28-03-2018 MKLM6_RS19840 c9caf38a3ebbd63a0e5e8d6b50ade0de 230 SMART SM00382 42 228 1.1E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS19840 c9caf38a3ebbd63a0e5e8d6b50ade0de 230 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS19840 c9caf38a3ebbd63a0e5e8d6b50ade0de 230 SUPERFAMILY SSF52540 13 230 8.11E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS19840 c9caf38a3ebbd63a0e5e8d6b50ade0de 230 Gene3D G3DSA:3.40.50.300 10 230 3.4E-63 T 28-03-2018 MKLM6_RS19840 c9caf38a3ebbd63a0e5e8d6b50ade0de 230 Pfam PF00005 ABC transporter 34 179 5.5E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS03195 d00aee1d8b2bf19dc2aa13b48fff36c9 315 Pfam PF13511 Domain of unknown function (DUF4124) 2 39 1.9E-9 T 28-03-2018 IPR025392 Domain of unknown function DUF4124 MKLM6_RS21405 c4e7e56f4d4996aa8ab4f2fecb92cdf6 321 SUPERFAMILY SSF46689 266 314 4.44E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS21405 c4e7e56f4d4996aa8ab4f2fecb92cdf6 321 SMART SM00342 229 313 1.9E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MKLM6_RS21405 c4e7e56f4d4996aa8ab4f2fecb92cdf6 321 Pfam PF12833 Helix-turn-helix domain 235 314 1.0E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MKLM6_RS21405 c4e7e56f4d4996aa8ab4f2fecb92cdf6 321 Gene3D G3DSA:2.60.120.10 56 268 2.8E-6 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS21405 c4e7e56f4d4996aa8ab4f2fecb92cdf6 321 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 266 309 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MKLM6_RS21405 c4e7e56f4d4996aa8ab4f2fecb92cdf6 321 Gene3D G3DSA:1.10.10.60 269 318 2.4E-10 T 28-03-2018 MKLM6_RS16475 83f9e98926851f8924e337f75de81727 162 Pfam PF07295 Zinc-ribbon containing domain 16 161 7.1E-44 T 28-03-2018 IPR009912 Zinc-ribbon containing domain MKLM6_RS08830 071d31bf91704c24080f4ad0c236e5a9 706 SUPERFAMILY SSF46626 207 249 1.47E-6 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS08830 071d31bf91704c24080f4ad0c236e5a9 706 SUPERFAMILY SSF46626 379 412 1.47E-6 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS08830 071d31bf91704c24080f4ad0c236e5a9 706 SUPERFAMILY SSF46626 532 609 5.65E-11 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS08830 071d31bf91704c24080f4ad0c236e5a9 706 SUPERFAMILY SSF46626 425 503 5.65E-11 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS08830 071d31bf91704c24080f4ad0c236e5a9 706 Gene3D G3DSA:1.10.760.10 184 420 8.3E-10 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS08830 071d31bf91704c24080f4ad0c236e5a9 706 Gene3D G3DSA:1.10.760.10 421 675 1.3E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS19175 98c9374df02be83f2b4010e4145c708a 569 Pfam PF05960 Bacterial protein of unknown function (DUF885) 52 564 1.4E-82 T 28-03-2018 IPR010281 Protein of unknown function DUF885 MKLM6_RS03910 6c25668dfa6e29ee8e03f4af49ed81fa 282 Pfam PF13525 Outer membrane lipoprotein 159 265 1.2E-10 T 28-03-2018 MKLM6_RS03910 6c25668dfa6e29ee8e03f4af49ed81fa 282 Pfam PF16331 TolA binding protein trimerisation 36 93 1.1E-13 T 28-03-2018 IPR032519 YbgF, trimerisation domain GO:0070206 MKLM6_RS03910 6c25668dfa6e29ee8e03f4af49ed81fa 282 Hamap MF_02066 Cell division coordinator CpoB [cpoB]. 3 280 18.267 T 28-03-2018 IPR034706 Cell division coordinator CpoB GO:0051301 MKLM6_RS03910 6c25668dfa6e29ee8e03f4af49ed81fa 282 SUPERFAMILY SSF48452 162 273 5.15E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS03910 6c25668dfa6e29ee8e03f4af49ed81fa 282 Gene3D G3DSA:1.20.120.330 36 95 4.8E-4 T 28-03-2018 MKLM6_RS03910 6c25668dfa6e29ee8e03f4af49ed81fa 282 Gene3D G3DSA:1.25.40.10 161 282 2.5E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS03910 6c25668dfa6e29ee8e03f4af49ed81fa 282 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 159 277 8.9E-32 T 28-03-2018 IPR014162 Cell division coordinator CpoB, C-terminal MKLM6_RS12635 f86a5d3f41335bf3377e7e4834d67e32 172 Pfam PF02674 Colicin V production protein 13 153 2.6E-37 T 28-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 MKLM6_RS16860 ec2862601a5954659d7759082c432fe4 308 SUPERFAMILY SSF53328 1 203 1.05E-67 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MKLM6_RS16860 ec2862601a5954659d7759082c432fe4 308 SUPERFAMILY SSF50486 204 300 4.12E-27 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 MKLM6_RS16860 ec2862601a5954659d7759082c432fe4 308 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 132 155 - T 28-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MKLM6_RS16860 ec2862601a5954659d7759082c432fe4 308 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 299 8.8E-98 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 MKLM6_RS16860 ec2862601a5954659d7759082c432fe4 308 Pfam PF02911 Formyl transferase, C-terminal domain 203 299 8.6E-24 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MKLM6_RS16860 ec2862601a5954659d7759082c432fe4 308 Pfam PF00551 Formyl transferase 1 180 3.1E-44 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MKLM6_RS16860 ec2862601a5954659d7759082c432fe4 308 Gene3D G3DSA:3.40.50.170 1 205 2.1E-70 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MKLM6_RS16860 ec2862601a5954659d7759082c432fe4 308 Gene3D G3DSA:3.10.25.10 206 302 1.1E-26 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MKLM6_RS16860 ec2862601a5954659d7759082c432fe4 308 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 302 36.782 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 MKLM6_RS18600 271242a6279826dc73b2953459ed9221 471 SUPERFAMILY SSF55874 329 468 2.23E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS18600 271242a6279826dc73b2953459ed9221 471 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 367 470 8.7E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS18600 271242a6279826dc73b2953459ed9221 471 SMART SM00387 364 471 1.4E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS18600 271242a6279826dc73b2953459ed9221 471 Pfam PF00512 His Kinase A (phospho-acceptor) domain 260 322 3.7E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS18600 271242a6279826dc73b2953459ed9221 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 416 1.1E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS18600 271242a6279826dc73b2953459ed9221 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 449 1.1E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS18600 271242a6279826dc73b2953459ed9221 471 SUPERFAMILY SSF47384 254 322 9.42E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS18600 271242a6279826dc73b2953459ed9221 471 SMART SM00388 259 324 5.5E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS18600 271242a6279826dc73b2953459ed9221 471 Gene3D G3DSA:1.10.287.130 244 320 2.7E-13 T 28-03-2018 MKLM6_RS18600 271242a6279826dc73b2953459ed9221 471 Gene3D G3DSA:3.30.565.10 322 471 1.5E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS21055 afe9294c628cf416b83bb27577c7b59b 126 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 126 67.031 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MKLM6_RS21055 afe9294c628cf416b83bb27577c7b59b 126 PIRSF PIRSF006246 1 125 3.5E-49 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MKLM6_RS21055 afe9294c628cf416b83bb27577c7b59b 126 Pfam PF02261 Aspartate decarboxylase 1 114 7.9E-47 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MKLM6_RS21055 afe9294c628cf416b83bb27577c7b59b 126 SUPERFAMILY SSF50692 1 120 4.97E-47 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain MKLM6_RS21055 afe9294c628cf416b83bb27577c7b59b 126 Gene3D G3DSA:2.40.40.20 1 117 2.4E-49 T 28-03-2018 MKLM6_RS21055 afe9294c628cf416b83bb27577c7b59b 126 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 123 5.0E-48 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MKLM6_RS21055 afe9294c628cf416b83bb27577c7b59b 126 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 125 6.8E-45 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MKLM6_RS10905 a3a03f79027cb2265403bdb5af684e2d 404 Gene3D G3DSA:1.25.40.10 104 196 1.6E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS10905 a3a03f79027cb2265403bdb5af684e2d 404 SUPERFAMILY SSF48452 153 275 4.22E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS10905 a3a03f79027cb2265403bdb5af684e2d 404 Gene3D G3DSA:1.25.40.10 197 278 2.9E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS10905 a3a03f79027cb2265403bdb5af684e2d 404 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 5 120 8.3E-26 T 28-03-2018 IPR017560 Cytochrome c-type biogenesis protein CcmI MKLM6_RS18775 c2640cf9fc206832abc57ae72ff52c23 288 PRINTS PR00996 Glutamate methyltransferase family signature 243 266 5.9E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS18775 c2640cf9fc206832abc57ae72ff52c23 288 PRINTS PR00996 Glutamate methyltransferase family signature 156 172 5.9E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS18775 c2640cf9fc206832abc57ae72ff52c23 288 PRINTS PR00996 Glutamate methyltransferase family signature 41 54 5.9E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS18775 c2640cf9fc206832abc57ae72ff52c23 288 PRINTS PR00996 Glutamate methyltransferase family signature 120 140 5.9E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS18775 c2640cf9fc206832abc57ae72ff52c23 288 PRINTS PR00996 Glutamate methyltransferase family signature 82 94 5.9E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS18775 c2640cf9fc206832abc57ae72ff52c23 288 PRINTS PR00996 Glutamate methyltransferase family signature 224 238 5.9E-40 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS18775 c2640cf9fc206832abc57ae72ff52c23 288 SUPERFAMILY SSF53335 89 268 9.24E-48 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS18775 c2640cf9fc206832abc57ae72ff52c23 288 SMART SM00138 19 286 1.2E-88 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS18775 c2640cf9fc206832abc57ae72ff52c23 288 SUPERFAMILY SSF47757 16 88 1.57E-13 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MKLM6_RS18775 c2640cf9fc206832abc57ae72ff52c23 288 Pfam PF03705 CheR methyltransferase, all-alpha domain 20 71 7.6E-12 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MKLM6_RS18775 c2640cf9fc206832abc57ae72ff52c23 288 Gene3D G3DSA:1.10.155.10 14 87 3.7E-13 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MKLM6_RS18775 c2640cf9fc206832abc57ae72ff52c23 288 Pfam PF01739 CheR methyltransferase, SAM binding domain 89 271 1.2E-56 T 28-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal MKLM6_RS18775 c2640cf9fc206832abc57ae72ff52c23 288 Gene3D G3DSA:3.40.50.150 88 286 2.1E-46 T 28-03-2018 MKLM6_RS18775 c2640cf9fc206832abc57ae72ff52c23 288 PIRSF PIRSF000410 5 286 9.5E-74 T 28-03-2018 IPR026024 Chemotaxis protein methyltransferase CheR MKLM6_RS08970 724b1cf08ce925417494aaf9feeba998 69 Pfam PF10049 Protein of unknown function (DUF2283) 2 49 2.2E-15 T 28-03-2018 IPR019270 Protein of unknown function DUF2283 MKLM6_RS05540 2462ed37848f9d67ec6ece628b131ad4 341 SUPERFAMILY SSF53822 75 310 1.55E-5 T 28-03-2018 IPR028082 Periplasmic binding protein-like I MKLM6_RS05540 2462ed37848f9d67ec6ece628b131ad4 341 Gene3D G3DSA:3.40.50.2300 36 162 7.7E-5 T 28-03-2018 MKLM6_RS05540 2462ed37848f9d67ec6ece628b131ad4 341 Gene3D G3DSA:3.40.50.2300 163 304 9.2E-11 T 28-03-2018 MKLM6_RS05540 2462ed37848f9d67ec6ece628b131ad4 341 Pfam PF04392 ABC transporter substrate binding protein 61 338 1.3E-28 T 28-03-2018 IPR007487 ABC transporter, substrate-binding protein MKLM6_RS11595 2c801f01b71c9401aa94183898d51ea9 479 Gene3D G3DSA:3.30.420.10 1 196 2.5E-27 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS11595 2c801f01b71c9401aa94183898d51ea9 479 Pfam PF08411 Exonuclease C-terminal 207 471 4.7E-95 T 28-03-2018 IPR013620 Exodeoxyribonuclease I, C-terminal GO:0006281|GO:0008852 MKLM6_RS11595 2c801f01b71c9401aa94183898d51ea9 479 Pfam PF00929 Exonuclease 8 188 2.6E-23 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MKLM6_RS11595 2c801f01b71c9401aa94183898d51ea9 479 PIRSF PIRSF000977 1 478 1.3E-207 T 28-03-2018 IPR023607 Exodeoxyribonuclease I GO:0004529 MKLM6_RS11595 2c801f01b71c9401aa94183898d51ea9 479 SUPERFAMILY SSF53098 5 468 1.69E-123 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS15380 61a7b7cfedaf2356ad6edd232d475b8e 342 Gene3D G3DSA:3.40.50.300 13 182 4.9E-13 T 28-03-2018 MKLM6_RS15380 61a7b7cfedaf2356ad6edd232d475b8e 342 SMART SM00382 42 248 3.9E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS15380 61a7b7cfedaf2356ad6edd232d475b8e 342 SUPERFAMILY SSF52540 6 263 1.03E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS15380 61a7b7cfedaf2356ad6edd232d475b8e 342 Pfam PF13401 AAA domain 42 169 3.6E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS15380 61a7b7cfedaf2356ad6edd232d475b8e 342 TIGRFAM TIGR03015 pepcterm_ATPase: putative secretion ATPase, PEP-CTERM locus subfamily 1 269 2.1E-99 T 28-03-2018 IPR017466 ATPase, secretion system, PEP-CTERM, predicted MKLM6_RS06360 1da552279fb0178e9da48b62407c877c 234 TIGRFAM TIGR03468 HpnG: hopanoid-associated phosphorylase 24 223 5.6E-63 T 28-03-2018 IPR017831 Hopanoid-associated phosphorylase HpnG MKLM6_RS06360 1da552279fb0178e9da48b62407c877c 234 Gene3D G3DSA:3.40.50.1580 3 199 2.0E-21 T 28-03-2018 MKLM6_RS06360 1da552279fb0178e9da48b62407c877c 234 Pfam PF01048 Phosphorylase superfamily 29 172 8.2E-19 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MKLM6_RS06360 1da552279fb0178e9da48b62407c877c 234 SUPERFAMILY SSF53167 3 172 4.06E-26 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MKLM6_RS02755 887515a25869a46cc568bbe6f8fecf4a 290 PIRSF PIRSF003092 5 284 3.4E-85 T 28-03-2018 IPR025501 ATP binding protein MinD MKLM6_RS02755 887515a25869a46cc568bbe6f8fecf4a 290 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 21 260 2.1E-20 T 28-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 MKLM6_RS02755 887515a25869a46cc568bbe6f8fecf4a 290 SUPERFAMILY SSF52540 21 275 2.57E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS02755 887515a25869a46cc568bbe6f8fecf4a 290 Gene3D G3DSA:3.40.50.300 20 262 1.6E-49 T 28-03-2018 MKLM6_RS07705 d37d460be042d372aabbcce72f21b274 938 Gene3D G3DSA:3.30.190.20 127 246 2.6E-41 T 28-03-2018 MKLM6_RS07705 d37d460be042d372aabbcce72f21b274 938 Gene3D G3DSA:3.40.50.300 33 76 0.029 T 28-03-2018 MKLM6_RS07705 d37d460be042d372aabbcce72f21b274 938 Gene3D G3DSA:3.40.50.300 606 937 4.4E-56 T 28-03-2018 MKLM6_RS07705 d37d460be042d372aabbcce72f21b274 938 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 4 922 0.0 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 MKLM6_RS07705 d37d460be042d372aabbcce72f21b274 938 SUPERFAMILY SSF52540 4 204 1.38E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS07705 d37d460be042d372aabbcce72f21b274 938 SUPERFAMILY SSF52540 428 567 1.38E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS07705 d37d460be042d372aabbcce72f21b274 938 Gene3D G3DSA:3.40.50.300 393 605 7.9E-29 T 28-03-2018 MKLM6_RS07705 d37d460be042d372aabbcce72f21b274 938 ProSitePatterns PS00211 ABC transporters family signature. 485 499 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS07705 d37d460be042d372aabbcce72f21b274 938 Gene3D G3DSA:3.40.50.300 1 32 4.7E-8 T 28-03-2018 MKLM6_RS07705 d37d460be042d372aabbcce72f21b274 938 Gene3D G3DSA:1.10.8.280 283 392 4.8E-35 T 28-03-2018 MKLM6_RS07705 d37d460be042d372aabbcce72f21b274 938 SUPERFAMILY SSF52540 612 911 7.31E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS07705 d37d460be042d372aabbcce72f21b274 938 ProSitePatterns PS00211 ABC transporters family signature. 827 841 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS07705 d37d460be042d372aabbcce72f21b274 938 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 937 22.427 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 MKLM6_RS11025 83a1e26a9aed3f02c8f613d91a2fb224 572 Gene3D G3DSA:3.40.50.300 312 561 7.8E-53 T 28-03-2018 MKLM6_RS11025 83a1e26a9aed3f02c8f613d91a2fb224 572 SMART SM00382 46 228 2.1E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS11025 83a1e26a9aed3f02c8f613d91a2fb224 572 SMART SM00382 345 527 1.7E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS11025 83a1e26a9aed3f02c8f613d91a2fb224 572 SUPERFAMILY SSF52540 315 542 2.1E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS11025 83a1e26a9aed3f02c8f613d91a2fb224 572 Gene3D G3DSA:3.40.50.300 14 245 1.3E-58 T 28-03-2018 MKLM6_RS11025 83a1e26a9aed3f02c8f613d91a2fb224 572 TIGRFAM TIGR01184 ntrCD: nitrate ABC transporter, ATP-binding proteins C and D 337 565 3.6E-94 T 28-03-2018 IPR005890 Nitrate transport ATP-binding subunit C/D GO:0015112|GO:0015706|GO:0016020 MKLM6_RS11025 83a1e26a9aed3f02c8f613d91a2fb224 572 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS11025 83a1e26a9aed3f02c8f613d91a2fb224 572 SUPERFAMILY SSF52540 17 245 3.39E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS11025 83a1e26a9aed3f02c8f613d91a2fb224 572 Pfam PF00005 ABC transporter 337 477 6.6E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS11025 83a1e26a9aed3f02c8f613d91a2fb224 572 Pfam PF00005 ABC transporter 37 178 4.9E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS20545 e7a07aa1aa463bf524a40784595e6bb8 246 Pfam PF08478 POTRA domain, FtsQ-type 32 100 1.7E-14 T 28-03-2018 IPR013685 POTRA domain, FtsQ-type MKLM6_RS20545 e7a07aa1aa463bf524a40784595e6bb8 246 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 1 225 21.392 T 28-03-2018 IPR026579 Cell division protein FtsQ GO:0090529 MKLM6_RS20545 e7a07aa1aa463bf524a40784595e6bb8 246 Pfam PF03799 Cell division protein FtsQ 105 217 1.3E-17 T 28-03-2018 IPR005548 Cell division protein FtsQ/DivIB MKLM6_RS06020 51765ce0b195a24b3ad56b2d080b07ca 886 Pfam PF00072 Response regulator receiver domain 494 610 1.8E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS06020 51765ce0b195a24b3ad56b2d080b07ca 886 Pfam PF00072 Response regulator receiver domain 638 751 7.3E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS06020 51765ce0b195a24b3ad56b2d080b07ca 886 Gene3D G3DSA:3.40.50.2300 489 626 1.4E-32 T 28-03-2018 MKLM6_RS06020 51765ce0b195a24b3ad56b2d080b07ca 886 Pfam PF00512 His Kinase A (phospho-acceptor) domain 245 309 1.5E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS06020 51765ce0b195a24b3ad56b2d080b07ca 886 SMART SM00387 357 473 6.6E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS06020 51765ce0b195a24b3ad56b2d080b07ca 886 SUPERFAMILY SSF55874 299 468 1.03E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS06020 51765ce0b195a24b3ad56b2d080b07ca 886 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 357 469 7.6E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS06020 51765ce0b195a24b3ad56b2d080b07ca 886 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 412 8.0E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS06020 51765ce0b195a24b3ad56b2d080b07ca 886 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 426 8.0E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS06020 51765ce0b195a24b3ad56b2d080b07ca 886 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 451 8.0E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS06020 51765ce0b195a24b3ad56b2d080b07ca 886 SUPERFAMILY SSF52172 489 615 8.68E-31 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS06020 51765ce0b195a24b3ad56b2d080b07ca 886 SUPERFAMILY SSF52172 636 754 8.97E-39 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS06020 51765ce0b195a24b3ad56b2d080b07ca 886 SMART SM00448 636 751 4.7E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS06020 51765ce0b195a24b3ad56b2d080b07ca 886 SMART SM00448 492 610 2.6E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS06020 51765ce0b195a24b3ad56b2d080b07ca 886 Pfam PF01627 Hpt domain 794 870 1.8E-10 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS06020 51765ce0b195a24b3ad56b2d080b07ca 886 Gene3D G3DSA:1.20.120.160 777 886 2.7E-15 T 28-03-2018 MKLM6_RS06020 51765ce0b195a24b3ad56b2d080b07ca 886 Gene3D G3DSA:3.40.50.2300 631 776 2.5E-41 T 28-03-2018 MKLM6_RS06020 51765ce0b195a24b3ad56b2d080b07ca 886 SMART SM00304 184 237 5.9E-4 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS06020 51765ce0b195a24b3ad56b2d080b07ca 886 Gene3D G3DSA:3.30.565.10 314 482 7.9E-47 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS06020 51765ce0b195a24b3ad56b2d080b07ca 886 SUPERFAMILY SSF47384 229 311 4.32E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS06020 51765ce0b195a24b3ad56b2d080b07ca 886 Gene3D G3DSA:1.10.287.130 235 306 1.7E-19 T 28-03-2018 MKLM6_RS06020 51765ce0b195a24b3ad56b2d080b07ca 886 SMART SM00388 245 310 3.5E-25 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS06020 51765ce0b195a24b3ad56b2d080b07ca 886 SUPERFAMILY SSF47226 734 868 2.09E-18 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS02220 97ac9e5307dfd728f8fff4f0fb544176 77 Gene3D G3DSA:3.10.20.30 1 77 7.4E-15 T 28-03-2018 IPR012675 Beta-grasp domain MKLM6_RS02220 97ac9e5307dfd728f8fff4f0fb544176 77 Pfam PF02597 ThiS family 5 77 6.7E-11 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 MKLM6_RS02220 97ac9e5307dfd728f8fff4f0fb544176 77 SUPERFAMILY SSF54285 3 77 1.81E-14 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MKLM6_RS19805 f9fac8305e17421d319583c2c5eaece7 322 SUPERFAMILY SSF55821 7 203 8.85E-67 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain MKLM6_RS19805 f9fac8305e17421d319583c2c5eaece7 322 PIRSF PIRSF004930 1 322 1.4E-111 T 28-03-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 MKLM6_RS19805 f9fac8305e17421d319583c2c5eaece7 322 Pfam PF03481 Putative GTP-binding controlling metal-binding 194 321 3.6E-19 T 28-03-2018 IPR005145 Putative GTP-binding controlling metal-binding domain MKLM6_RS19805 f9fac8305e17421d319583c2c5eaece7 322 Pfam PF01300 Telomere recombination 17 192 2.0E-58 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 MKLM6_RS19805 f9fac8305e17421d319583c2c5eaece7 322 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 203 5.7E-61 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 MKLM6_RS19805 f9fac8305e17421d319583c2c5eaece7 322 Gene3D G3DSA:3.90.870.10 1 208 3.3E-81 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain MKLM6_RS10785 1e7bd2efa4ca3a6edc57c9ae1281a2db 359 Pfam PF00266 Aminotransferase class-V 4 348 2.1E-58 T 28-03-2018 IPR000192 Aminotransferase class V domain MKLM6_RS10785 1e7bd2efa4ca3a6edc57c9ae1281a2db 359 Gene3D G3DSA:3.90.1150.10 258 358 7.3E-37 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS10785 1e7bd2efa4ca3a6edc57c9ae1281a2db 359 PIRSF PIRSF000525 1 359 4.7E-148 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 MKLM6_RS10785 1e7bd2efa4ca3a6edc57c9ae1281a2db 359 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 2 359 49.702 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 MKLM6_RS10785 1e7bd2efa4ca3a6edc57c9ae1281a2db 359 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 187 206 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MKLM6_RS10785 1e7bd2efa4ca3a6edc57c9ae1281a2db 359 Gene3D G3DSA:3.40.640.10 16 257 1.4E-29 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS10785 1e7bd2efa4ca3a6edc57c9ae1281a2db 359 SUPERFAMILY SSF53383 1 357 3.1E-116 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS10785 1e7bd2efa4ca3a6edc57c9ae1281a2db 359 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 4 359 3.3E-153 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 MKLM6_RS16955 2fac4e19e03a59c41e008f66b4ac1595 504 Gene3D G3DSA:3.30.1890.10 62 419 4.9E-17 T 28-03-2018 MKLM6_RS09315 b829678f01da8697e263701520e2e387 367 Gene3D G3DSA:3.40.640.10 2 238 5.6E-49 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS09315 b829678f01da8697e263701520e2e387 367 SUPERFAMILY SSF53383 8 364 8.93E-115 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS09315 b829678f01da8697e263701520e2e387 367 Gene3D G3DSA:3.90.1150.10 239 367 1.0E-42 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS09315 b829678f01da8697e263701520e2e387 367 PIRSF PIRSF000390 3 367 6.1E-112 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MKLM6_RS09315 b829678f01da8697e263701520e2e387 367 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 359 1.1E-130 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MKLM6_RS10345 c6ee2a1d01a83ef01f38313625e35dff 225 SUPERFAMILY SSF75445 128 206 6.93E-24 T 28-03-2018 MKLM6_RS10345 c6ee2a1d01a83ef01f38313625e35dff 225 Gene3D G3DSA:3.30.70.260 140 204 1.3E-22 T 28-03-2018 MKLM6_RS10345 c6ee2a1d01a83ef01f38313625e35dff 225 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 51 219 4.8E-57 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MKLM6_RS10345 c6ee2a1d01a83ef01f38313625e35dff 225 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 7 219 6.3E-66 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MKLM6_RS10345 c6ee2a1d01a83ef01f38313625e35dff 225 SUPERFAMILY SSF100950 1 148 4.54E-42 T 28-03-2018 MKLM6_RS10345 c6ee2a1d01a83ef01f38313625e35dff 225 Gene3D G3DSA:3.40.50.1360 1 139 9.2E-38 T 28-03-2018 MKLM6_RS10345 c6ee2a1d01a83ef01f38313625e35dff 225 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 225 31.498 T 28-03-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MKLM6_RS05135 c2989113271e3e763af4e842b25d2d95 553 Gene3D G3DSA:3.30.70.1450 298 369 4.1E-11 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MKLM6_RS05135 c2989113271e3e763af4e842b25d2d95 553 Gene3D G3DSA:3.30.70.1450 199 287 9.3E-6 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MKLM6_RS05135 c2989113271e3e763af4e842b25d2d95 553 Pfam PF06826 Predicted Permease Membrane Region 378 549 3.9E-43 T 28-03-2018 IPR006512 YidE/YbjL duplication MKLM6_RS05135 c2989113271e3e763af4e842b25d2d95 553 Pfam PF06826 Predicted Permease Membrane Region 20 182 7.3E-39 T 28-03-2018 IPR006512 YidE/YbjL duplication MKLM6_RS05135 c2989113271e3e763af4e842b25d2d95 553 SUPERFAMILY SSF116726 288 365 2.22E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MKLM6_RS05135 c2989113271e3e763af4e842b25d2d95 553 SUPERFAMILY SSF116726 219 277 2.75E-6 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MKLM6_RS05135 c2989113271e3e763af4e842b25d2d95 553 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 383 536 9.9E-44 T 28-03-2018 IPR006512 YidE/YbjL duplication MKLM6_RS05135 c2989113271e3e763af4e842b25d2d95 553 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 27 172 1.7E-30 T 28-03-2018 IPR006512 YidE/YbjL duplication MKLM6_RS05135 c2989113271e3e763af4e842b25d2d95 553 Pfam PF02080 TrkA-C domain 301 363 4.4E-7 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MKLM6_RS11870 6cf071603a2a5989b6d1b758fe756087 196 Gene3D G3DSA:1.20.1440.20 14 194 2.8E-54 T 28-03-2018 MKLM6_RS11870 6cf071603a2a5989b6d1b758fe756087 196 SUPERFAMILY SSF140478 24 181 1.18E-53 T 28-03-2018 IPR023353 LemA-like domain MKLM6_RS11870 6cf071603a2a5989b6d1b758fe756087 196 Pfam PF04011 LemA family 8 194 1.3E-66 T 28-03-2018 IPR007156 LemA MKLM6_RS10060 f854dfd61919f9ee98c1fa02e908d890 260 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 79 87 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MKLM6_RS10060 f854dfd61919f9ee98c1fa02e908d890 260 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 170 181 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MKLM6_RS10060 f854dfd61919f9ee98c1fa02e908d890 260 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 31 251 6.7E-86 T 28-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MKLM6_RS10060 f854dfd61919f9ee98c1fa02e908d890 260 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 29 133 2.4E-34 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MKLM6_RS10060 f854dfd61919f9ee98c1fa02e908d890 260 Gene3D G3DSA:1.10.1060.10 128 259 4.5E-32 T 28-03-2018 MKLM6_RS10060 f854dfd61919f9ee98c1fa02e908d890 260 SUPERFAMILY SSF46548 128 257 8.89E-39 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MKLM6_RS10060 f854dfd61919f9ee98c1fa02e908d890 260 Pfam PF13237 4Fe-4S dicluster domain 169 238 2.0E-9 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MKLM6_RS10060 f854dfd61919f9ee98c1fa02e908d890 260 Gene3D G3DSA:3.10.20.30 20 126 4.7E-35 T 28-03-2018 IPR012675 Beta-grasp domain MKLM6_RS10060 f854dfd61919f9ee98c1fa02e908d890 260 SUPERFAMILY SSF54292 27 127 1.37E-30 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MKLM6_RS07260 ab9970c71de911ffa82b11e9116da669 90 SMART SM00834 1 42 6.2E-19 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain MKLM6_RS07260 ab9970c71de911ffa82b11e9116da669 90 Pfam PF09723 Zinc ribbon domain 1 41 3.8E-16 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain MKLM6_RS07260 ab9970c71de911ffa82b11e9116da669 90 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 52 7.1E-21 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain MKLM6_RS15080 7e5fa063ad661107d8572c22195b6148 147 Gene3D G3DSA:3.30.420.10 1 145 1.2E-54 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS15080 7e5fa063ad661107d8572c22195b6148 147 Pfam PF00075 RNase H 4 141 9.0E-52 T 28-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 MKLM6_RS15080 7e5fa063ad661107d8572c22195b6148 147 Hamap MF_00042 Ribonuclease H [rnhA]. 2 146 32.312 T 28-03-2018 IPR022892 Ribonuclease HI GO:0004523 MKLM6_RS15080 7e5fa063ad661107d8572c22195b6148 147 SUPERFAMILY SSF53098 4 143 1.06E-57 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS10240 2c49e46379f7983b68d9f185292ac461 496 SUPERFAMILY SSF56672 53 251 4.45E-31 T 28-03-2018 MKLM6_RS10240 2c49e46379f7983b68d9f185292ac461 496 Pfam PF00817 impB/mucB/samB family 44 173 2.5E-9 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MKLM6_RS15070 378fe510fc0b315ca91657dca8a909ed 83 Pfam PF01541 GIY-YIG catalytic domain 4 73 3.5E-15 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily MKLM6_RS15070 378fe510fc0b315ca91657dca8a909ed 83 Gene3D G3DSA:3.40.1440.10 2 76 1.8E-8 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily MKLM6_RS15070 378fe510fc0b315ca91657dca8a909ed 83 SUPERFAMILY SSF82771 4 72 4.97E-14 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily MKLM6_RS13330 5bac18ba09131604ac6833cf363f1383 267 SUPERFAMILY SSF47240 76 216 8.59E-16 T 28-03-2018 IPR009078 Ferritin-like superfamily MKLM6_RS13330 5bac18ba09131604ac6833cf363f1383 267 Gene3D G3DSA:1.20.1260.10 63 231 1.2E-41 T 28-03-2018 IPR012347 Ferritin-related MKLM6_RS13330 5bac18ba09131604ac6833cf363f1383 267 Pfam PF04305 Protein of unknown function (DUF455) 15 258 1.1E-88 T 28-03-2018 IPR007402 Protein of unknown function DUF455 MKLM6_RS13330 5bac18ba09131604ac6833cf363f1383 267 PIRSF PIRSF012318 1 267 1.2E-88 T 28-03-2018 IPR011197 Uncharacterised conserved protein UCP012318 MKLM6_RS02590 98121c24911f4ae58e9ae82752e220b3 335 SMART SM00267 143 318 3.8E-41 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS02590 98121c24911f4ae58e9ae82752e220b3 335 Gene3D G3DSA:3.30.70.270 147 322 1.0E-46 T 28-03-2018 MKLM6_RS02590 98121c24911f4ae58e9ae82752e220b3 335 Pfam PF00990 Diguanylate cyclase, GGDEF domain 156 314 1.8E-36 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS02590 98121c24911f4ae58e9ae82752e220b3 335 SUPERFAMILY SSF55073 159 319 7.3E-40 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS02590 98121c24911f4ae58e9ae82752e220b3 335 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 155 317 2.3E-37 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS07770 9713ba2893773163bf5ac8f0c84212cc 267 Gene3D G3DSA:1.20.1170.10 21 213 1.1E-9 T 28-03-2018 MKLM6_RS01395 6d8ab98cb9e1a541a459bd245bc01673 219 SUPERFAMILY SSF52172 1 122 1.24E-35 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS01395 6d8ab98cb9e1a541a459bd245bc01673 219 Pfam PF00072 Response regulator receiver domain 4 112 1.0E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS01395 6d8ab98cb9e1a541a459bd245bc01673 219 SMART SM00448 1 112 3.0E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS01395 6d8ab98cb9e1a541a459bd245bc01673 219 Gene3D G3DSA:3.40.50.2300 1 117 2.4E-34 T 28-03-2018 MKLM6_RS01395 6d8ab98cb9e1a541a459bd245bc01673 219 Gene3D G3DSA:1.10.10.10 118 219 9.6E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS01395 6d8ab98cb9e1a541a459bd245bc01673 219 SUPERFAMILY SSF46894 120 216 3.12E-26 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MKLM6_RS01395 6d8ab98cb9e1a541a459bd245bc01673 219 SMART SM00862 145 216 6.3E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS01395 6d8ab98cb9e1a541a459bd245bc01673 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 215 2.4E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS14955 fdd5580164cad7c03085657161948e93 112 PIRSF PIRSF039144 1 112 1.9E-53 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MKLM6_RS14955 fdd5580164cad7c03085657161948e93 112 Gene3D G3DSA:3.30.70.120 1 109 1.0E-48 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MKLM6_RS14955 fdd5580164cad7c03085657161948e93 112 SUPERFAMILY SSF54913 1 112 2.83E-45 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MKLM6_RS14955 fdd5580164cad7c03085657161948e93 112 PRINTS PR00340 P-II protein signature 83 103 9.7E-42 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MKLM6_RS14955 fdd5580164cad7c03085657161948e93 112 PRINTS PR00340 P-II protein signature 2 17 9.7E-42 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MKLM6_RS14955 fdd5580164cad7c03085657161948e93 112 PRINTS PR00340 P-II protein signature 52 75 9.7E-42 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MKLM6_RS14955 fdd5580164cad7c03085657161948e93 112 PRINTS PR00340 P-II protein signature 23 41 9.7E-42 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MKLM6_RS14955 fdd5580164cad7c03085657161948e93 112 SMART SM00938 4 105 1.9E-65 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MKLM6_RS14955 fdd5580164cad7c03085657161948e93 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 4.8E-43 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MKLM6_RS14955 fdd5580164cad7c03085657161948e93 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 28-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 MKLM6_RS14955 fdd5580164cad7c03085657161948e93 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 28-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 MKLM6_RS02335 9cadc4d5e0a75d386adc6f840a1f6f83 194 Pfam PF01725 Ham1 family 4 189 5.3E-56 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 MKLM6_RS02335 9cadc4d5e0a75d386adc6f840a1f6f83 194 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 194 46.774 T 28-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 MKLM6_RS02335 9cadc4d5e0a75d386adc6f840a1f6f83 194 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 192 3.1E-56 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 MKLM6_RS02335 9cadc4d5e0a75d386adc6f840a1f6f83 194 SUPERFAMILY SSF52972 2 192 2.62E-67 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MKLM6_RS02335 9cadc4d5e0a75d386adc6f840a1f6f83 194 Gene3D G3DSA:3.90.950.10 1 194 2.9E-73 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MKLM6_RS18710 a93cfdd9819902ad32686ae695a84302 155 Pfam PF14437 MafB19-like deaminase 10 106 1.0E-22 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 MKLM6_RS18710 a93cfdd9819902ad32686ae695a84302 155 Gene3D G3DSA:3.40.140.10 1 155 2.1E-38 T 28-03-2018 MKLM6_RS18710 a93cfdd9819902ad32686ae695a84302 155 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 52 89 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MKLM6_RS18710 a93cfdd9819902ad32686ae695a84302 155 SUPERFAMILY SSF53927 2 141 2.3E-43 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 MKLM6_RS00390 d7f4ba3bbba49500ebc0d25136edcad8 180 Gene3D G3DSA:3.40.30.10 26 179 3.1E-30 T 28-03-2018 MKLM6_RS00390 d7f4ba3bbba49500ebc0d25136edcad8 180 PIRSF PIRSF000303 3 180 7.9E-54 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MKLM6_RS00390 d7f4ba3bbba49500ebc0d25136edcad8 180 PRINTS PR01011 Glutathione peroxidase family signature 141 150 2.1E-10 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MKLM6_RS00390 d7f4ba3bbba49500ebc0d25136edcad8 180 PRINTS PR01011 Glutathione peroxidase family signature 81 97 2.1E-10 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MKLM6_RS00390 d7f4ba3bbba49500ebc0d25136edcad8 180 PRINTS PR01011 Glutathione peroxidase family signature 46 63 2.1E-10 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MKLM6_RS00390 d7f4ba3bbba49500ebc0d25136edcad8 180 SUPERFAMILY SSF52833 28 177 3.11E-41 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS00390 d7f4ba3bbba49500ebc0d25136edcad8 180 Pfam PF00255 Glutathione peroxidase 37 133 4.2E-26 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MKLM6_RS13930 d2c5d259b1c5badbe824add3e80d9f01 182 SUPERFAMILY SSF117916 81 180 6.87E-30 T 28-03-2018 IPR034904 Fe-S cluster assembly domain MKLM6_RS13930 d2c5d259b1c5badbe824add3e80d9f01 182 Gene3D G3DSA:3.30.300.130 78 181 4.6E-27 T 28-03-2018 IPR034904 Fe-S cluster assembly domain MKLM6_RS13930 d2c5d259b1c5badbe824add3e80d9f01 182 Pfam PF01883 Iron-sulfur cluster assembly protein 84 160 2.4E-21 T 28-03-2018 IPR002744 MIP18 family-like MKLM6_RS13930 d2c5d259b1c5badbe824add3e80d9f01 182 TIGRFAM TIGR03406 FeS_long_SufT: probable FeS assembly SUF system protein SufT 7 181 2.4E-72 T 28-03-2018 IPR017776 FeS assembly SUF system protein SufT, putative MKLM6_RS07010 7b06002fe6e5b9a416f3cc8eb63c4694 294 SUPERFAMILY SSF53335 63 285 1.53E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS07010 7b06002fe6e5b9a416f3cc8eb63c4694 294 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 286 4.1E-84 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 MKLM6_RS07010 7b06002fe6e5b9a416f3cc8eb63c4694 294 PIRSF PIRSF000401 1 294 6.0E-82 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 MKLM6_RS07010 7b06002fe6e5b9a416f3cc8eb63c4694 294 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 291 8.7E-88 T 28-03-2018 MKLM6_RS07010 7b06002fe6e5b9a416f3cc8eb63c4694 294 Gene3D G3DSA:3.40.50.150 101 294 9.7E-34 T 28-03-2018 MKLM6_RS07010 7b06002fe6e5b9a416f3cc8eb63c4694 294 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 292 31.603 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 MKLM6_RS15715 7288a90e37647eee2162cd943aa79691 451 Pfam PF01136 Peptidase family U32 76 352 4.0E-98 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 MKLM6_RS15715 7288a90e37647eee2162cd943aa79691 451 ProSitePatterns PS01276 Peptidase family U32 signature. 162 180 - T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 MKLM6_RS15715 7288a90e37647eee2162cd943aa79691 451 Gene3D G3DSA:3.20.20.70 3 172 0.001 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS15715 7288a90e37647eee2162cd943aa79691 451 Pfam PF16325 Peptidase family U32 C-terminal domain 368 449 1.5E-17 T 28-03-2018 IPR032525 Peptidase family U32, C-terminal MKLM6_RS01385 a94d034834a859e671f660349ee71c06 396 Gene3D G3DSA:2.120.10.10 44 190 1.6E-20 T 28-03-2018 MKLM6_RS01385 a94d034834a859e671f660349ee71c06 396 Gene3D G3DSA:2.120.10.10 191 276 1.0E-8 T 28-03-2018 MKLM6_RS01385 a94d034834a859e671f660349ee71c06 396 Gene3D G3DSA:2.120.10.10 280 395 1.1E-11 T 28-03-2018 MKLM6_RS01385 a94d034834a859e671f660349ee71c06 396 SUPERFAMILY SSF50939 52 321 8.83E-29 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 MKLM6_RS01385 a94d034834a859e671f660349ee71c06 396 SUPERFAMILY SSF50939 285 385 4.32E-12 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 MKLM6_RS01385 a94d034834a859e671f660349ee71c06 396 Pfam PF13088 BNR repeat-like domain 66 251 1.2E-12 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 MKLM6_RS20475 ac8a438623e33700c0674f9549657bea 333 Gene3D G3DSA:3.40.50.720 2 179 2.6E-37 T 28-03-2018 MKLM6_RS20475 ac8a438623e33700c0674f9549657bea 333 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 3 322 36.535 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MKLM6_RS20475 ac8a438623e33700c0674f9549657bea 333 SUPERFAMILY SSF51735 5 178 2.88E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS20475 ac8a438623e33700c0674f9549657bea 333 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 4 158 1.8E-43 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MKLM6_RS20475 ac8a438623e33700c0674f9549657bea 333 SUPERFAMILY SSF48179 180 331 7.48E-56 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MKLM6_RS20475 ac8a438623e33700c0674f9549657bea 333 PIRSF PIRSF000114 1 332 3.3E-99 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MKLM6_RS20475 ac8a438623e33700c0674f9549657bea 333 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 188 209 - T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MKLM6_RS20475 ac8a438623e33700c0674f9549657bea 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 57 84 2.4E-44 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MKLM6_RS20475 ac8a438623e33700c0674f9549657bea 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 238 255 2.4E-44 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MKLM6_RS20475 ac8a438623e33700c0674f9549657bea 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 198 222 2.4E-44 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MKLM6_RS20475 ac8a438623e33700c0674f9549657bea 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 133 153 2.4E-44 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MKLM6_RS20475 ac8a438623e33700c0674f9549657bea 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 173 197 2.4E-44 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MKLM6_RS20475 ac8a438623e33700c0674f9549657bea 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 7 24 2.4E-44 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MKLM6_RS20475 ac8a438623e33700c0674f9549657bea 333 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 180 320 3.5E-51 T 28-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MKLM6_RS20475 ac8a438623e33700c0674f9549657bea 333 Gene3D G3DSA:1.10.1040.10 180 330 9.7E-54 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MKLM6_RS09410 ce0d9d770d3f07c6602264a6786bca7e 419 Gene3D G3DSA:3.90.1150.10 276 416 5.9E-63 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS09410 ce0d9d770d3f07c6602264a6786bca7e 419 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 222 238 - T 28-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MKLM6_RS09410 ce0d9d770d3f07c6602264a6786bca7e 419 Pfam PF00464 Serine hydroxymethyltransferase 10 386 2.0E-183 T 28-03-2018 MKLM6_RS09410 ce0d9d770d3f07c6602264a6786bca7e 419 SUPERFAMILY SSF53383 6 416 9.25E-187 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS09410 ce0d9d770d3f07c6602264a6786bca7e 419 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 417 53.286 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MKLM6_RS09410 ce0d9d770d3f07c6602264a6786bca7e 419 Gene3D G3DSA:3.40.640.10 37 275 8.3E-51 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS09410 ce0d9d770d3f07c6602264a6786bca7e 419 PIRSF PIRSF000412 1 419 1.3E-173 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MKLM6_RS02915 d7aa4d0536ec733f66a11e1084c75f91 176 Pfam PF07589 PEP-CTERM motif 152 175 2.3E-4 T 28-03-2018 IPR013424 PEP-CTERM protein-sorting domain MKLM6_RS02915 d7aa4d0536ec733f66a11e1084c75f91 176 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 153 175 2.6E-4 T 28-03-2018 IPR013424 PEP-CTERM protein-sorting domain MKLM6_RS18980 df82a73b2d960bc4098b2739d059e09e 540 SUPERFAMILY SSF47384 175 251 1.86E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS18980 df82a73b2d960bc4098b2739d059e09e 540 SMART SM00388 184 250 1.5E-24 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS18980 df82a73b2d960bc4098b2739d059e09e 540 Gene3D G3DSA:3.30.565.10 245 412 1.3E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS18980 df82a73b2d960bc4098b2739d059e09e 540 Pfam PF00512 His Kinase A (phospho-acceptor) domain 184 249 3.4E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS18980 df82a73b2d960bc4098b2739d059e09e 540 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 298 409 4.6E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS18980 df82a73b2d960bc4098b2739d059e09e 540 SUPERFAMILY SSF55874 239 409 1.13E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS18980 df82a73b2d960bc4098b2739d059e09e 540 Gene3D G3DSA:3.30.450.40 5 149 1.7E-6 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS18980 df82a73b2d960bc4098b2739d059e09e 540 SMART SM00387 297 413 1.1E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS18980 df82a73b2d960bc4098b2739d059e09e 540 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 391 1.7E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS18980 df82a73b2d960bc4098b2739d059e09e 540 PRINTS PR00344 Bacterial sensor protein C-terminal signature 338 352 1.7E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS18980 df82a73b2d960bc4098b2739d059e09e 540 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 410 1.7E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS18980 df82a73b2d960bc4098b2739d059e09e 540 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 366 1.7E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS18980 df82a73b2d960bc4098b2739d059e09e 540 SUPERFAMILY SSF55781 14 148 3.71E-8 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS18980 df82a73b2d960bc4098b2739d059e09e 540 Gene3D G3DSA:1.10.287.130 175 244 1.0E-19 T 28-03-2018 MKLM6_RS05650 a4c8803c741a81b67ba3317e8a40ce77 384 Pfam PF02684 Lipid-A-disaccharide synthetase 10 348 2.9E-96 T 28-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 MKLM6_RS05650 a4c8803c741a81b67ba3317e8a40ce77 384 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 5 373 3.6E-88 T 28-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 MKLM6_RS05650 a4c8803c741a81b67ba3317e8a40ce77 384 SUPERFAMILY SSF53756 11 381 3.43E-40 T 28-03-2018 MKLM6_RS05650 a4c8803c741a81b67ba3317e8a40ce77 384 Gene3D G3DSA:3.40.50.2000 6 183 9.0E-8 T 28-03-2018 MKLM6_RS05650 a4c8803c741a81b67ba3317e8a40ce77 384 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 7 381 32.323 T 28-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 MKLM6_RS05650 a4c8803c741a81b67ba3317e8a40ce77 384 Gene3D G3DSA:3.40.50.2000 184 364 2.5E-18 T 28-03-2018 MKLM6_RS03685 05c94f5688ed299ec07a598c5447319e 253 SUPERFAMILY SSF69572 2 246 2.88E-86 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MKLM6_RS03685 05c94f5688ed299ec07a598c5447319e 253 Gene3D G3DSA:3.40.50.720 1 247 1.4E-73 T 28-03-2018 MKLM6_RS03685 05c94f5688ed299ec07a598c5447319e 253 Pfam PF00899 ThiF family 9 242 2.4E-64 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MKLM6_RS21035 93f8edd2e6ee6c04ac61766cbc6f8d0d 454 SUPERFAMILY SSF56935 11 452 6.11E-77 T 28-03-2018 MKLM6_RS21035 93f8edd2e6ee6c04ac61766cbc6f8d0d 454 Pfam PF00593 TonB dependent receptor 18 451 5.3E-61 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS21035 93f8edd2e6ee6c04ac61766cbc6f8d0d 454 Gene3D G3DSA:2.40.170.20 3 454 6.0E-67 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS20085 923628d1ba25d1cdc8694e89cd49d3a5 186 Pfam PF14220 Domain of unknown function (DUF4329) 54 171 3.5E-14 T 28-03-2018 IPR025479 Domain of unknown function DUF4329 MKLM6_RS03730 33af0282aa99a817482cd6016a81c39b 212 SUPERFAMILY SSF52540 1 188 1.07E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS03730 33af0282aa99a817482cd6016a81c39b 212 PRINTS PR00094 Adenylate kinase signature 173 187 2.0E-35 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MKLM6_RS03730 33af0282aa99a817482cd6016a81c39b 212 PRINTS PR00094 Adenylate kinase signature 4 17 2.0E-35 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MKLM6_RS03730 33af0282aa99a817482cd6016a81c39b 212 PRINTS PR00094 Adenylate kinase signature 81 97 2.0E-35 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MKLM6_RS03730 33af0282aa99a817482cd6016a81c39b 212 PRINTS PR00094 Adenylate kinase signature 156 171 2.0E-35 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MKLM6_RS03730 33af0282aa99a817482cd6016a81c39b 212 PRINTS PR00094 Adenylate kinase signature 32 46 2.0E-35 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MKLM6_RS03730 33af0282aa99a817482cd6016a81c39b 212 Pfam PF00406 Adenylate kinase 5 186 2.2E-57 T 28-03-2018 MKLM6_RS03730 33af0282aa99a817482cd6016a81c39b 212 Hamap MF_00235 Adenylate kinase [adk]. 1 212 52.242 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MKLM6_RS03730 33af0282aa99a817482cd6016a81c39b 212 TIGRFAM TIGR01351 adk: adenylate kinase 2 209 8.5E-76 T 28-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 MKLM6_RS03730 33af0282aa99a817482cd6016a81c39b 212 Gene3D G3DSA:3.40.50.300 1 212 1.2E-66 T 28-03-2018 MKLM6_RS03730 33af0282aa99a817482cd6016a81c39b 212 Pfam PF05191 Adenylate kinase, active site lid 123 158 1.9E-18 T 28-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 MKLM6_RS03730 33af0282aa99a817482cd6016a81c39b 212 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 28-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MKLM6_RS11765 f6af8b0489b2ea9c45ac2b1ebc6e5cdd 635 ProSitePatterns PS00674 AAA-protein family signature. 296 314 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 MKLM6_RS11765 f6af8b0489b2ea9c45ac2b1ebc6e5cdd 635 Pfam PF01434 Peptidase family M41 386 593 2.4E-75 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 MKLM6_RS11765 f6af8b0489b2ea9c45ac2b1ebc6e5cdd 635 Pfam PF06480 FtsH Extracellular 10 92 1.0E-8 T 28-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 MKLM6_RS11765 f6af8b0489b2ea9c45ac2b1ebc6e5cdd 635 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 101 594 2.7E-227 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 MKLM6_RS11765 f6af8b0489b2ea9c45ac2b1ebc6e5cdd 635 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 609 36.426 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 MKLM6_RS11765 f6af8b0489b2ea9c45ac2b1ebc6e5cdd 635 SMART SM00382 188 328 1.3E-25 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS11765 f6af8b0489b2ea9c45ac2b1ebc6e5cdd 635 SUPERFAMILY SSF52540 147 396 6.98E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS11765 f6af8b0489b2ea9c45ac2b1ebc6e5cdd 635 SUPERFAMILY SSF140990 407 603 4.32E-70 T 28-03-2018 MKLM6_RS11765 f6af8b0489b2ea9c45ac2b1ebc6e5cdd 635 Gene3D G3DSA:3.40.50.300 133 338 8.5E-63 T 28-03-2018 MKLM6_RS11765 f6af8b0489b2ea9c45ac2b1ebc6e5cdd 635 Gene3D G3DSA:1.10.8.60 339 413 4.9E-22 T 28-03-2018 MKLM6_RS11765 f6af8b0489b2ea9c45ac2b1ebc6e5cdd 635 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 192 325 3.5E-45 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MKLM6_RS13325 42efd42b92c4fb77cd7baf63dd9fa909 391 Pfam PF05940 NnrS protein 10 385 1.4E-99 T 28-03-2018 IPR010266 NnrS MKLM6_RS18990 94e40a0a9e608df357d9f0568ab7dec0 342 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 7 337 3.0E-33 T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MKLM6_RS18990 94e40a0a9e608df357d9f0568ab7dec0 342 SUPERFAMILY SSF51726 2 340 4.53E-36 T 28-03-2018 MKLM6_RS18990 94e40a0a9e608df357d9f0568ab7dec0 342 Gene3D G3DSA:3.20.20.210 1 339 3.9E-38 T 28-03-2018 MKLM6_RS14730 4c1d91ae8f6ed77b9250a2a1bc6ec8bd 106 Gene3D G3DSA:3.40.30.10 1 106 1.3E-35 T 28-03-2018 MKLM6_RS14730 4c1d91ae8f6ed77b9250a2a1bc6ec8bd 106 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 4 100 7.3E-45 T 28-03-2018 IPR004480 Monothiol glutaredoxin-related MKLM6_RS14730 4c1d91ae8f6ed77b9250a2a1bc6ec8bd 106 Pfam PF00462 Glutaredoxin 16 80 8.6E-20 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 MKLM6_RS14730 4c1d91ae8f6ed77b9250a2a1bc6ec8bd 106 PIRSF PIRSF005894 1 106 1.0E-47 T 28-03-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 MKLM6_RS14730 4c1d91ae8f6ed77b9250a2a1bc6ec8bd 106 SUPERFAMILY SSF52833 2 104 3.24E-37 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS02905 c5f53e0c5d0adea062f0956a18533968 478 PIRSF PIRSF004919 14 477 8.1E-145 T 28-03-2018 IPR025502 TldD MKLM6_RS02905 c5f53e0c5d0adea062f0956a18533968 478 SUPERFAMILY SSF111283 19 476 4.19E-130 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 MKLM6_RS02905 c5f53e0c5d0adea062f0956a18533968 478 Gene3D G3DSA:3.30.2290.10 17 236 1.8E-47 T 28-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain MKLM6_RS02905 c5f53e0c5d0adea062f0956a18533968 478 Pfam PF01523 Putative modulator of DNA gyrase 36 328 1.3E-67 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 MKLM6_RS17305 e870c8d12574e895bfdccf7cc76c9ea3 559 Gene3D G3DSA:3.30.300.30 334 454 7.0E-12 T 28-03-2018 MKLM6_RS17305 e870c8d12574e895bfdccf7cc76c9ea3 559 SUPERFAMILY SSF54637 457 552 2.58E-10 T 28-03-2018 IPR029069 HotDog domain MKLM6_RS17305 e870c8d12574e895bfdccf7cc76c9ea3 559 Gene3D G3DSA:3.10.129.10 455 559 4.3E-14 T 28-03-2018 MKLM6_RS17305 e870c8d12574e895bfdccf7cc76c9ea3 559 Gene3D G3DSA:3.40.50.980 8 107 0.24 T 28-03-2018 MKLM6_RS17305 e870c8d12574e895bfdccf7cc76c9ea3 559 SUPERFAMILY SSF56801 18 438 2.09E-42 T 28-03-2018 MKLM6_RS17305 e870c8d12574e895bfdccf7cc76c9ea3 559 Pfam PF00501 AMP-binding enzyme 115 276 6.6E-14 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MKLM6_RS17305 e870c8d12574e895bfdccf7cc76c9ea3 559 Gene3D G3DSA:3.40.50.980 108 289 8.4E-19 T 28-03-2018 MKLM6_RS21245 34af8d15fb78c964f87220bc7f2ae940 134 Pfam PF02472 Biopolymer transport protein ExbD/TolR 12 131 1.9E-29 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 MKLM6_RS10445 34af8d15fb78c964f87220bc7f2ae940 134 Pfam PF02472 Biopolymer transport protein ExbD/TolR 12 131 1.9E-29 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 MKLM6_RS07125 0d243daecc69572397d6ff16b00ddadf 143 Gene3D G3DSA:3.30.70.141 1 55 7.6E-20 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MKLM6_RS07125 0d243daecc69572397d6ff16b00ddadf 143 Gene3D G3DSA:3.30.70.141 56 140 2.7E-37 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MKLM6_RS07125 0d243daecc69572397d6ff16b00ddadf 143 SUPERFAMILY SSF54919 1 141 9.69E-63 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MKLM6_RS07125 0d243daecc69572397d6ff16b00ddadf 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 1.2E-42 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MKLM6_RS07125 0d243daecc69572397d6ff16b00ddadf 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 1.2E-42 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MKLM6_RS07125 0d243daecc69572397d6ff16b00ddadf 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 1.2E-42 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MKLM6_RS07125 0d243daecc69572397d6ff16b00ddadf 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 1.2E-42 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MKLM6_RS07125 0d243daecc69572397d6ff16b00ddadf 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 1.2E-42 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MKLM6_RS07125 0d243daecc69572397d6ff16b00ddadf 143 SMART SM00562 3 140 5.2E-94 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MKLM6_RS07125 0d243daecc69572397d6ff16b00ddadf 143 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 37.388 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MKLM6_RS07125 0d243daecc69572397d6ff16b00ddadf 143 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 28-03-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MKLM6_RS07125 0d243daecc69572397d6ff16b00ddadf 143 Pfam PF00334 Nucleoside diphosphate kinase 4 137 9.4E-60 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MKLM6_RS13270 cf09e50adceac92b4caf4adb48c2dfbb 130 Pfam PF01814 Hemerythrin HHE cation binding domain 14 122 7.2E-8 T 28-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 MKLM6_RS13270 cf09e50adceac92b4caf4adb48c2dfbb 130 ProSitePatterns PS00550 Hemerythrin family signature. 53 76 - T 28-03-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 MKLM6_RS13270 cf09e50adceac92b4caf4adb48c2dfbb 130 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 11 125 5.6E-19 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 MKLM6_RS13270 cf09e50adceac92b4caf4adb48c2dfbb 130 SUPERFAMILY SSF47188 11 124 2.75E-22 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 MKLM6_RS13270 cf09e50adceac92b4caf4adb48c2dfbb 130 Gene3D G3DSA:1.20.120.50 3 130 3.0E-25 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 MKLM6_RS13790 010f64f8942ad03c9e6b7dbb8ef65912 289 Gene3D G3DSA:3.40.250.10 1 155 6.2E-30 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS13790 010f64f8942ad03c9e6b7dbb8ef65912 289 SUPERFAMILY SSF52821 2 146 9.95E-40 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS13790 010f64f8942ad03c9e6b7dbb8ef65912 289 Gene3D G3DSA:3.40.250.10 157 288 1.8E-19 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS13790 010f64f8942ad03c9e6b7dbb8ef65912 289 SMART SM00450 153 276 5.8E-5 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS13790 010f64f8942ad03c9e6b7dbb8ef65912 289 SMART SM00450 7 133 8.8E-20 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS13790 010f64f8942ad03c9e6b7dbb8ef65912 289 Pfam PF00581 Rhodanese-like domain 9 128 5.0E-18 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS13790 010f64f8942ad03c9e6b7dbb8ef65912 289 Pfam PF00581 Rhodanese-like domain 158 272 3.1E-7 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS13790 010f64f8942ad03c9e6b7dbb8ef65912 289 SUPERFAMILY SSF52821 164 281 2.23E-27 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS13180 97dda7d7c55ae2140f88a423493ac45f 768 SUPERFAMILY SSF55785 369 493 1.92E-8 T 28-03-2018 IPR000014 PAS domain MKLM6_RS13180 97dda7d7c55ae2140f88a423493ac45f 768 PIRSF PIRSF037347 2 389 2.9E-69 T 28-03-2018 IPR017181 Signal transduction histidine kinase, CHASE2 sensor domain-containing, predicted MKLM6_RS13180 97dda7d7c55ae2140f88a423493ac45f 768 PIRSF PIRSF037347 515 757 1.6E-31 T 28-03-2018 IPR017181 Signal transduction histidine kinase, CHASE2 sensor domain-containing, predicted MKLM6_RS13180 97dda7d7c55ae2140f88a423493ac45f 768 Gene3D G3DSA:1.10.287.130 516 589 8.4E-18 T 28-03-2018 MKLM6_RS13180 97dda7d7c55ae2140f88a423493ac45f 768 SMART SM01080 28 309 2.2E-59 T 28-03-2018 IPR007890 CHASE2 MKLM6_RS13180 97dda7d7c55ae2140f88a423493ac45f 768 Pfam PF05226 CHASE2 domain 19 304 2.1E-46 T 28-03-2018 IPR007890 CHASE2 MKLM6_RS13180 97dda7d7c55ae2140f88a423493ac45f 768 SUPERFAMILY SSF55874 584 755 4.06E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13180 97dda7d7c55ae2140f88a423493ac45f 768 Gene3D G3DSA:3.30.450.20 364 513 7.9E-13 T 28-03-2018 MKLM6_RS13180 97dda7d7c55ae2140f88a423493ac45f 768 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 643 753 2.4E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13180 97dda7d7c55ae2140f88a423493ac45f 768 SMART SM00387 642 754 1.6E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13180 97dda7d7c55ae2140f88a423493ac45f 768 Pfam PF00512 His Kinase A (phospho-acceptor) domain 526 595 5.6E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS13180 97dda7d7c55ae2140f88a423493ac45f 768 Gene3D G3DSA:3.30.565.10 590 754 5.0E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13180 97dda7d7c55ae2140f88a423493ac45f 768 SUPERFAMILY SSF47384 513 596 1.43E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS13180 97dda7d7c55ae2140f88a423493ac45f 768 PRINTS PR00344 Bacterial sensor protein C-terminal signature 714 732 6.1E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13180 97dda7d7c55ae2140f88a423493ac45f 768 PRINTS PR00344 Bacterial sensor protein C-terminal signature 680 694 6.1E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13180 97dda7d7c55ae2140f88a423493ac45f 768 PRINTS PR00344 Bacterial sensor protein C-terminal signature 738 751 6.1E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS13180 97dda7d7c55ae2140f88a423493ac45f 768 SMART SM00388 526 595 2.7E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS22280 633d8093e25726c7413d3d19bb3ef321 196 Pfam PF08747 Domain of unknown function (DUF1788) 64 191 4.8E-41 T 28-03-2018 IPR014858 Protein of unknown function DUF1788 MKLM6_RS09430 da7637df6489b31d31a0671583950c4d 234 SUPERFAMILY SSF56300 1 195 1.28E-27 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS09430 da7637df6489b31d31a0671583950c4d 234 Gene3D G3DSA:3.60.21.10 3 187 7.5E-18 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS15155 1a24f2c52e31ed97789b52606b926b61 543 Gene3D G3DSA:3.30.450.20 42 165 3.9E-25 T 28-03-2018 MKLM6_RS15155 1a24f2c52e31ed97789b52606b926b61 543 Gene3D G3DSA:3.30.450.20 166 344 4.5E-11 T 28-03-2018 MKLM6_RS15155 1a24f2c52e31ed97789b52606b926b61 543 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 475 5.5E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS15155 1a24f2c52e31ed97789b52606b926b61 543 PRINTS PR00344 Bacterial sensor protein C-terminal signature 479 489 5.5E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS15155 1a24f2c52e31ed97789b52606b926b61 543 PRINTS PR00344 Bacterial sensor protein C-terminal signature 494 512 5.5E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS15155 1a24f2c52e31ed97789b52606b926b61 543 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 531 5.5E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS15155 1a24f2c52e31ed97789b52606b926b61 543 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 44 162 8.6E-18 T 28-03-2018 IPR000014 PAS domain MKLM6_RS15155 1a24f2c52e31ed97789b52606b926b61 543 TIGRFAM TIGR02938 nifL_nitrog: nitrogen fixation negative regulator NifL 39 531 7.0E-198 T 28-03-2018 IPR014285 Nitrogen fixation negative regulator NifL GO:0004871|GO:0007165|GO:0009399|GO:0050660 MKLM6_RS15155 1a24f2c52e31ed97789b52606b926b61 543 SUPERFAMILY SSF55874 369 532 6.16E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS15155 1a24f2c52e31ed97789b52606b926b61 543 SMART SM00086 114 156 9.3E-6 T 28-03-2018 IPR001610 PAC motif MKLM6_RS15155 1a24f2c52e31ed97789b52606b926b61 543 SUPERFAMILY SSF55785 50 153 2.44E-24 T 28-03-2018 IPR000014 PAS domain MKLM6_RS15155 1a24f2c52e31ed97789b52606b926b61 543 Gene3D G3DSA:3.30.565.10 379 537 2.2E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS15155 1a24f2c52e31ed97789b52606b926b61 543 SUPERFAMILY SSF55785 152 197 9.21E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS15155 1a24f2c52e31ed97789b52606b926b61 543 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 421 531 1.5E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS15155 1a24f2c52e31ed97789b52606b926b61 543 Pfam PF13426 PAS domain 52 155 4.0E-17 T 28-03-2018 IPR000014 PAS domain MKLM6_RS15155 1a24f2c52e31ed97789b52606b926b61 543 SMART SM00387 420 534 2.6E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS15155 1a24f2c52e31ed97789b52606b926b61 543 SMART SM00091 168 234 21.0 T 28-03-2018 IPR000014 PAS domain MKLM6_RS15155 1a24f2c52e31ed97789b52606b926b61 543 SMART SM00091 42 108 1.3E-5 T 28-03-2018 IPR000014 PAS domain MKLM6_RS02295 7352a08c2e14c7cf2c9ef5c0f40d58eb 490 Pfam PF00361 Proton-conducting membrane transporter 127 418 2.1E-65 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS02295 7352a08c2e14c7cf2c9ef5c0f40d58eb 490 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 4 483 5.4E-143 T 28-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS02295 7352a08c2e14c7cf2c9ef5c0f40d58eb 490 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 237 261 6.4E-40 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS02295 7352a08c2e14c7cf2c9ef5c0f40d58eb 490 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 376 402 6.4E-40 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS02295 7352a08c2e14c7cf2c9ef5c0f40d58eb 490 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 324 343 6.4E-40 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS02295 7352a08c2e14c7cf2c9ef5c0f40d58eb 490 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 163 187 6.4E-40 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS02295 7352a08c2e14c7cf2c9ef5c0f40d58eb 490 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 133 152 6.4E-40 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS08460 e60925fa7cf58cc8f6cb623af84c6e39 330 Gene3D G3DSA:1.20.1170.10 105 324 3.9E-5 T 28-03-2018 MKLM6_RS08460 e60925fa7cf58cc8f6cb623af84c6e39 330 Pfam PF02470 MlaD protein 37 142 3.4E-13 T 28-03-2018 IPR003399 Mce/MlaD MKLM6_RS01560 9ac5f529fc87c9ca55fba8ed0fd033a9 553 SUPERFAMILY SSF141523 305 362 7.06E-14 T 28-03-2018 MKLM6_RS01560 9ac5f529fc87c9ca55fba8ed0fd033a9 553 SUPERFAMILY SSF141523 406 456 7.06E-14 T 28-03-2018 MKLM6_RS01560 9ac5f529fc87c9ca55fba8ed0fd033a9 553 Gene3D G3DSA:1.10.101.10 204 281 3.8E-14 T 28-03-2018 IPR002477 Peptidoglycan binding-like MKLM6_RS01560 9ac5f529fc87c9ca55fba8ed0fd033a9 553 SUPERFAMILY SSF47090 211 285 7.61E-12 T 28-03-2018 IPR002477 Peptidoglycan binding-like MKLM6_RS01560 9ac5f529fc87c9ca55fba8ed0fd033a9 553 Gene3D G3DSA:2.40.440.10 306 464 1.4E-19 T 28-03-2018 MKLM6_RS01560 9ac5f529fc87c9ca55fba8ed0fd033a9 553 Pfam PF01471 Putative peptidoglycan binding domain 226 276 1.1E-8 T 28-03-2018 IPR002477 Peptidoglycan binding-like MKLM6_RS01560 9ac5f529fc87c9ca55fba8ed0fd033a9 553 Pfam PF03734 L,D-transpeptidase catalytic domain 307 464 1.1E-25 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MKLM6_RS04600 7083eefe08e1538ac7f9fe6bc4ef5952 286 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 183 203 - T 28-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 MKLM6_RS04600 7083eefe08e1538ac7f9fe6bc4ef5952 286 Gene3D G3DSA:3.10.50.40 133 268 6.9E-32 T 28-03-2018 MKLM6_RS04600 7083eefe08e1538ac7f9fe6bc4ef5952 286 SUPERFAMILY SSF109998 35 172 6.28E-17 T 28-03-2018 IPR027304 Trigger factor/SurA domain MKLM6_RS04600 7083eefe08e1538ac7f9fe6bc4ef5952 286 Pfam PF00639 PPIC-type PPIASE domain 148 241 6.3E-22 T 28-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 MKLM6_RS04600 7083eefe08e1538ac7f9fe6bc4ef5952 286 TIGRFAM TIGR02933 nifM_nitrog: nitrogen fixation protein NifM 12 279 5.9E-64 T 28-03-2018 IPR014282 Nitrogen fixation protein NifM MKLM6_RS04600 7083eefe08e1538ac7f9fe6bc4ef5952 286 SUPERFAMILY SSF54534 134 242 2.49E-26 T 28-03-2018 MKLM6_RS04600 7083eefe08e1538ac7f9fe6bc4ef5952 286 Gene3D G3DSA:1.10.4030.10 16 118 4.2E-7 T 28-03-2018 MKLM6_RS04955 9726cdb0b1d34c2f8a726d15fd17824a 143 SUPERFAMILY SSF53146 3 121 4.32E-31 T 28-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis MKLM6_RS04955 9726cdb0b1d34c2f8a726d15fd17824a 143 TIGRFAM TIGR02663 nifX: nitrogen fixation protein NifX 5 121 5.2E-35 T 28-03-2018 IPR013480 Nitrogen fixation protein NifX GO:0009399|GO:0051188|GO:0051540 MKLM6_RS04955 9726cdb0b1d34c2f8a726d15fd17824a 143 Gene3D G3DSA:3.30.420.130 1 122 9.4E-33 T 28-03-2018 MKLM6_RS04955 9726cdb0b1d34c2f8a726d15fd17824a 143 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 16 106 8.5E-20 T 28-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis MKLM6_RS09530 2a1349a8f13cc5f2f175bab5b7eef32a 273 Pfam PF00561 alpha/beta hydrolase fold 22 254 5.1E-27 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS09530 2a1349a8f13cc5f2f175bab5b7eef32a 273 SUPERFAMILY SSF53474 2 272 8.64E-65 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS09530 2a1349a8f13cc5f2f175bab5b7eef32a 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 1.3E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS09530 2a1349a8f13cc5f2f175bab5b7eef32a 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 1.3E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS09530 2a1349a8f13cc5f2f175bab5b7eef32a 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 216 230 1.3E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS09530 2a1349a8f13cc5f2f175bab5b7eef32a 273 Gene3D G3DSA:3.40.50.1820 1 273 9.0E-61 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS19525 d7026fd379476be7eac67bfa6e49d60e 368 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 215 364 1.0E-16 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MKLM6_RS19525 d7026fd379476be7eac67bfa6e49d60e 368 Pfam PF00364 Biotin-requiring enzyme 17 74 6.4E-11 T 28-03-2018 IPR000089 Biotin/lipoyl attachment MKLM6_RS19525 d7026fd379476be7eac67bfa6e49d60e 368 Gene3D G3DSA:3.30.559.10 146 365 1.5E-22 T 28-03-2018 MKLM6_RS19525 d7026fd379476be7eac67bfa6e49d60e 368 SUPERFAMILY SSF51230 6 85 2.09E-14 T 28-03-2018 IPR011053 Single hybrid motif MKLM6_RS19525 d7026fd379476be7eac67bfa6e49d60e 368 SUPERFAMILY SSF52777 183 364 4.27E-22 T 28-03-2018 MKLM6_RS19525 d7026fd379476be7eac67bfa6e49d60e 368 Gene3D G3DSA:2.40.50.100 18 77 3.3E-10 T 28-03-2018 MKLM6_RS21380 a6b4fee91ae2fefb476670e5247db60a 316 Pfam PF01479 S4 domain 15 61 4.9E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MKLM6_RS21380 a6b4fee91ae2fefb476670e5247db60a 316 Pfam PF00849 RNA pseudouridylate synthase 89 238 9.4E-37 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS21380 a6b4fee91ae2fefb476670e5247db60a 316 Gene3D G3DSA:3.30.2350.10 79 312 1.1E-70 T 28-03-2018 MKLM6_RS21380 a6b4fee91ae2fefb476670e5247db60a 316 SUPERFAMILY SSF55120 74 309 1.42E-79 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS21380 a6b4fee91ae2fefb476670e5247db60a 316 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 11 308 6.1E-100 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS21380 a6b4fee91ae2fefb476670e5247db60a 316 SUPERFAMILY SSF55174 15 68 4.37E-10 T 28-03-2018 MKLM6_RS21380 a6b4fee91ae2fefb476670e5247db60a 316 SMART SM00363 15 75 1.2E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MKLM6_RS21380 a6b4fee91ae2fefb476670e5247db60a 316 Gene3D G3DSA:3.10.290.10 2 71 2.2E-19 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MKLM6_RS21380 a6b4fee91ae2fefb476670e5247db60a 316 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 131 145 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS22475 6560771a48fa64b1e709f6306b131858 92 Gene3D G3DSA:1.10.4000.10 1 88 4.4E-11 T 28-03-2018 MKLM6_RS22475 6560771a48fa64b1e709f6306b131858 92 Pfam PF05247 Flagellar transcriptional activator (FlhD) 2 78 6.3E-7 T 28-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 MKLM6_RS22475 6560771a48fa64b1e709f6306b131858 92 SUPERFAMILY SSF63592 3 80 3.79E-8 T 28-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 MKLM6_RS16555 c9b177fa7b0e9f2c6fce5985b70286e7 207 Hamap MF_00695 High frequency lysogenization protein HflD [hflD]. 2 205 32.225 T 28-03-2018 IPR007451 Uncharacterised protein family UPF0274 MKLM6_RS16555 c9b177fa7b0e9f2c6fce5985b70286e7 207 ProDom PD037115 UPF0274 YCFC HI0638 METABOLISM UNCHARACTERIZED VV1342 PURINE INVOLVED SO2634 HFLD 11 193 5.0E-47 T 28-03-2018 IPR007451 Uncharacterised protein family UPF0274 MKLM6_RS16555 c9b177fa7b0e9f2c6fce5985b70286e7 207 Gene3D G3DSA:1.10.3890.10 5 205 7.0E-72 T 28-03-2018 IPR007451 Uncharacterised protein family UPF0274 MKLM6_RS16555 c9b177fa7b0e9f2c6fce5985b70286e7 207 Pfam PF04356 Protein of unknown function (DUF489) 8 196 5.7E-69 T 28-03-2018 IPR007451 Uncharacterised protein family UPF0274 MKLM6_RS16555 c9b177fa7b0e9f2c6fce5985b70286e7 207 SUPERFAMILY SSF101322 5 206 2.35E-63 T 28-03-2018 IPR007451 Uncharacterised protein family UPF0274 MKLM6_RS16830 24f96cca0d3122567ed25821a206f5ea 161 Pfam PF02643 Uncharacterized ACR, COG1430 46 149 1.7E-30 T 28-03-2018 IPR003795 Protein of unknown function DUF192 MKLM6_RS16205 e4586f5e1e2f588ccc1e57b611e18775 327 SMART SM00327 81 261 3.1E-15 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS16205 e4586f5e1e2f588ccc1e57b611e18775 327 Pfam PF13519 von Willebrand factor type A domain 84 198 2.8E-13 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS16205 e4586f5e1e2f588ccc1e57b611e18775 327 SUPERFAMILY SSF53300 82 236 1.63E-18 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS16205 e4586f5e1e2f588ccc1e57b611e18775 327 Gene3D G3DSA:3.40.50.410 79 305 5.2E-24 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS10790 93a5115e095cb18d7acc90269dc67aab 361 SMART SM00830 11 92 5.2E-31 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MKLM6_RS10790 93a5115e095cb18d7acc90269dc67aab 361 Gene3D G3DSA:1.20.59.10 1 98 2.7E-35 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MKLM6_RS10790 93a5115e095cb18d7acc90269dc67aab 361 PIRSF PIRSF001500 3 361 1.1E-135 T 28-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MKLM6_RS10790 93a5115e095cb18d7acc90269dc67aab 361 Gene3D G3DSA:3.40.190.10 179 258 2.0E-23 T 28-03-2018 MKLM6_RS10790 93a5115e095cb18d7acc90269dc67aab 361 Gene3D G3DSA:3.30.70.260 269 360 6.1E-31 T 28-03-2018 MKLM6_RS10790 93a5115e095cb18d7acc90269dc67aab 361 Pfam PF00800 Prephenate dehydratase 94 269 9.0E-60 T 28-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MKLM6_RS10790 93a5115e095cb18d7acc90269dc67aab 361 Pfam PF01817 Chorismate mutase type II 11 90 4.2E-23 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MKLM6_RS10790 93a5115e095cb18d7acc90269dc67aab 361 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 244 266 - T 28-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MKLM6_RS10790 93a5115e095cb18d7acc90269dc67aab 361 SUPERFAMILY SSF55021 263 358 2.95E-30 T 28-03-2018 MKLM6_RS10790 93a5115e095cb18d7acc90269dc67aab 361 Pfam PF01842 ACT domain 279 344 6.4E-14 T 28-03-2018 IPR002912 ACT domain MKLM6_RS10790 93a5115e095cb18d7acc90269dc67aab 361 SUPERFAMILY SSF53850 93 272 4.02E-54 T 28-03-2018 MKLM6_RS10790 93a5115e095cb18d7acc90269dc67aab 361 TIGRFAM TIGR01807 CM_P2: chorismate mutase 7 82 5.7E-29 T 28-03-2018 IPR010957 Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 MKLM6_RS10790 93a5115e095cb18d7acc90269dc67aab 361 SUPERFAMILY SSF48600 7 94 5.65E-21 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MKLM6_RS10790 93a5115e095cb18d7acc90269dc67aab 361 Gene3D G3DSA:3.40.190.10 99 178 6.9E-30 T 28-03-2018 MKLM6_RS22075 3a74f03707b96165c2e697beee514b60 332 TIGRFAM TIGR03033 phage_rel_nuc: putative phage-type endonuclease 5 158 2.3E-35 T 28-03-2018 IPR017482 Putative phage-type endonuclease MKLM6_RS22075 3a74f03707b96165c2e697beee514b60 332 Gene3D G3DSA:3.90.320.10 1 204 1.4E-39 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 MKLM6_RS22075 3a74f03707b96165c2e697beee514b60 332 SUPERFAMILY SSF52980 1 194 4.56E-40 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MKLM6_RS22075 3a74f03707b96165c2e697beee514b60 332 Pfam PF09588 YqaJ-like viral recombinase domain 13 148 3.2E-20 T 28-03-2018 IPR019080 YqaJ viral recombinase MKLM6_RS08135 7ea50ddf7624dd10f18f5c078b16a082 340 Gene3D G3DSA:3.90.180.10 2 154 5.9E-21 T 28-03-2018 MKLM6_RS08135 7ea50ddf7624dd10f18f5c078b16a082 340 Gene3D G3DSA:3.40.50.720 155 279 2.1E-9 T 28-03-2018 MKLM6_RS08135 7ea50ddf7624dd10f18f5c078b16a082 340 SUPERFAMILY SSF51735 125 279 1.61E-16 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS08135 7ea50ddf7624dd10f18f5c078b16a082 340 SUPERFAMILY SSF50129 6 157 6.92E-19 T 28-03-2018 IPR011032 GroES-like MKLM6_RS05435 39a672ecd778290cc4519afbf400666a 263 Gene3D G3DSA:3.30.65.10 210 263 2.4E-14 T 28-03-2018 MKLM6_RS05435 39a672ecd778290cc4519afbf400666a 263 SUPERFAMILY SSF57783 217 262 1.24E-7 T 28-03-2018 MKLM6_RS05435 39a672ecd778290cc4519afbf400666a 263 Pfam PF08378 Nuclease-related domain 37 148 1.4E-28 T 28-03-2018 IPR011528 Nuclease-related domain, NERD MKLM6_RS05435 39a672ecd778290cc4519afbf400666a 263 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 224 263 5.5E-10 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 MKLM6_RS17260 b247a2290b6c3414185925bd67a93be3 179 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 15 163 2.1E-29 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS17260 b247a2290b6c3414185925bd67a93be3 179 Gene3D G3DSA:3.40.50.700 1 179 2.2E-41 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS17260 b247a2290b6c3414185925bd67a93be3 179 SUPERFAMILY SSF56770 4 177 5.49E-39 T 28-03-2018 MKLM6_RS02115 0b6564ccc82e4a5ea5b674da5ca29428 434 SUPERFAMILY SSF51338 3 56 2.62E-27 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MKLM6_RS02115 0b6564ccc82e4a5ea5b674da5ca29428 434 SUPERFAMILY SSF51338 368 424 2.62E-27 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MKLM6_RS02115 0b6564ccc82e4a5ea5b674da5ca29428 434 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 24 424 1.7E-96 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS02115 0b6564ccc82e4a5ea5b674da5ca29428 434 SUPERFAMILY SSF51556 57 369 1.16E-87 T 28-03-2018 IPR032466 Metal-dependent hydrolase MKLM6_RS02115 0b6564ccc82e4a5ea5b674da5ca29428 434 Gene3D G3DSA:2.30.40.10 2 71 2.9E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MKLM6_RS02115 0b6564ccc82e4a5ea5b674da5ca29428 434 Pfam PF01979 Amidohydrolase family 53 391 4.7E-16 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MKLM6_RS02115 0b6564ccc82e4a5ea5b674da5ca29428 434 Hamap MF_00220_B Dihydroorotase [pyrC]. 3 426 31.61 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MKLM6_RS02115 0b6564ccc82e4a5ea5b674da5ca29428 434 Gene3D G3DSA:3.20.20.140 72 389 1.4E-80 T 28-03-2018 MKLM6_RS01260 cb82774297cf5c9ace7ab2b2a72dba95 129 Pfam PF04234 CopC domain 26 118 8.2E-14 T 28-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 MKLM6_RS01260 cb82774297cf5c9ace7ab2b2a72dba95 129 SUPERFAMILY SSF81296 23 118 2.87E-13 T 28-03-2018 IPR014756 Immunoglobulin E-set MKLM6_RS01260 cb82774297cf5c9ace7ab2b2a72dba95 129 Gene3D G3DSA:2.60.40.1220 22 119 3.2E-16 T 28-03-2018 MKLM6_RS09735 f7f08ce79103b29f7197ae75732fc5e8 112 Pfam PF16785 Small metal-binding protein 2 110 2.4E-8 T 28-03-2018 IPR031877 Metal-binding protein SmbP GO:0046872 MKLM6_RS02010 b242b0e5c613cbd29ec12d85ef1c4ad9 506 Pfam PF05681 Fumarate hydratase (Fumerase) 11 284 1.3E-97 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 MKLM6_RS02010 b242b0e5c613cbd29ec12d85ef1c4ad9 506 Pfam PF05683 Fumarase C-terminus 288 489 2.7E-80 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 MKLM6_RS02010 b242b0e5c613cbd29ec12d85ef1c4ad9 506 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 12 285 1.5E-60 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 MKLM6_RS02010 b242b0e5c613cbd29ec12d85ef1c4ad9 506 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 324 487 1.4E-45 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 MKLM6_RS02010 b242b0e5c613cbd29ec12d85ef1c4ad9 506 SUPERFAMILY SSF117457 316 487 7.98E-61 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 MKLM6_RS02010 b242b0e5c613cbd29ec12d85ef1c4ad9 506 Gene3D G3DSA:3.20.130.10 313 488 4.1E-63 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 MKLM6_RS02010 b242b0e5c613cbd29ec12d85ef1c4ad9 506 PIRSF PIRSF001394 1 506 3.0E-213 T 28-03-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 MKLM6_RS11920 e678465792d6a8ff813e9630a8f94cf0 186 Gene3D G3DSA:3.10.560.10 94 186 5.0E-24 T 28-03-2018 MKLM6_RS11920 e678465792d6a8ff813e9630a8f94cf0 186 Gene3D G3DSA:3.30.1950.10 32 93 6.5E-17 T 28-03-2018 MKLM6_RS11920 e678465792d6a8ff813e9630a8f94cf0 186 Pfam PF02563 Polysaccharide biosynthesis/export protein 24 98 1.6E-21 T 28-03-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 MKLM6_RS07680 d1d98455cb7b9fe8c8c9aece0ef55517 135 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 5 132 11.491 T 28-03-2018 IPR022907 VapC family GO:0004540 MKLM6_RS07680 d1d98455cb7b9fe8c8c9aece0ef55517 135 Gene3D G3DSA:3.40.50.1010 2 135 1.3E-27 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS07680 d1d98455cb7b9fe8c8c9aece0ef55517 135 SUPERFAMILY SSF88723 3 133 5.89E-33 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS07680 d1d98455cb7b9fe8c8c9aece0ef55517 135 Pfam PF01850 PIN domain 5 126 1.5E-15 T 28-03-2018 IPR002716 PIN domain MKLM6_RS07180 189961f3a99b9556f79beb7b6fc90656 258 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 62 78 9.4E-26 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MKLM6_RS07180 189961f3a99b9556f79beb7b6fc90656 258 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 126 138 9.4E-26 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MKLM6_RS07180 189961f3a99b9556f79beb7b6fc90656 258 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 201 220 9.4E-26 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MKLM6_RS07180 189961f3a99b9556f79beb7b6fc90656 258 Pfam PF00717 Peptidase S24-like 68 149 3.2E-24 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MKLM6_RS07180 189961f3a99b9556f79beb7b6fc90656 258 SUPERFAMILY SSF51306 60 253 7.74E-73 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MKLM6_RS07180 189961f3a99b9556f79beb7b6fc90656 258 Pfam PF10502 Signal peptidase, peptidase S26 196 238 1.3E-6 T 28-03-2018 IPR019533 Peptidase S26 MKLM6_RS07180 189961f3a99b9556f79beb7b6fc90656 258 ProSitePatterns PS00760 Signal peptidases I lysine active site. 128 140 - T 28-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 MKLM6_RS07180 189961f3a99b9556f79beb7b6fc90656 258 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 47 240 6.3E-54 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MKLM6_RS07180 189961f3a99b9556f79beb7b6fc90656 258 ProSitePatterns PS00501 Signal peptidases I serine active site. 71 78 - T 28-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 MKLM6_RS07180 189961f3a99b9556f79beb7b6fc90656 258 ProSitePatterns PS00761 Signal peptidases I signature 3. 206 219 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 MKLM6_RS07180 189961f3a99b9556f79beb7b6fc90656 258 Gene3D G3DSA:2.10.109.10 58 253 1.4E-59 T 28-03-2018 MKLM6_RS18085 5da5f8f9a88175edf2c9def3559c1abe 438 Pfam PF00529 HlyD membrane-fusion protein of T1SS 31 393 2.4E-12 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MKLM6_RS18085 5da5f8f9a88175edf2c9def3559c1abe 438 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 21 437 5.2E-117 T 28-03-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 MKLM6_RS18085 5da5f8f9a88175edf2c9def3559c1abe 438 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 28 51 1.7E-54 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MKLM6_RS18085 5da5f8f9a88175edf2c9def3559c1abe 438 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 417 437 1.7E-54 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MKLM6_RS18085 5da5f8f9a88175edf2c9def3559c1abe 438 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 70 90 1.7E-54 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MKLM6_RS18085 5da5f8f9a88175edf2c9def3559c1abe 438 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 302 323 1.7E-54 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MKLM6_RS18085 5da5f8f9a88175edf2c9def3559c1abe 438 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 359 382 1.7E-54 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MKLM6_RS18085 5da5f8f9a88175edf2c9def3559c1abe 438 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 402 417 1.7E-54 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MKLM6_RS18085 5da5f8f9a88175edf2c9def3559c1abe 438 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 335 359 1.7E-54 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MKLM6_RS18085 5da5f8f9a88175edf2c9def3559c1abe 438 SUPERFAMILY SSF111369 67 145 9.81E-5 T 28-03-2018 MKLM6_RS18085 5da5f8f9a88175edf2c9def3559c1abe 438 Gene3D G3DSA:2.40.50.100 53 320 5.9E-17 T 28-03-2018 MKLM6_RS18085 5da5f8f9a88175edf2c9def3559c1abe 438 ProSitePatterns PS00543 HlyD family secretion proteins signature. 402 424 - T 28-03-2018 IPR006144 Secretion protein HlyD, conserved site GO:0008565|GO:0009306|GO:0016020 MKLM6_RS14385 f6a106e430e4cf86e5867e4af3069cc2 486 SMART SM00387 375 482 1.8E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14385 f6a106e430e4cf86e5867e4af3069cc2 486 SMART SM00388 266 335 2.6E-4 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS14385 f6a106e430e4cf86e5867e4af3069cc2 486 Gene3D G3DSA:1.10.287.130 252 345 4.5E-6 T 28-03-2018 MKLM6_RS14385 f6a106e430e4cf86e5867e4af3069cc2 486 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 379 478 2.3E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14385 f6a106e430e4cf86e5867e4af3069cc2 486 SUPERFAMILY SSF47384 257 331 4.51E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS14385 f6a106e430e4cf86e5867e4af3069cc2 486 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 460 2.3E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14385 f6a106e430e4cf86e5867e4af3069cc2 486 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 427 2.3E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS14385 f6a106e430e4cf86e5867e4af3069cc2 486 Gene3D G3DSA:3.30.565.10 346 486 5.3E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS14385 f6a106e430e4cf86e5867e4af3069cc2 486 SUPERFAMILY SSF55874 332 479 2.23E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS12205 52c8480e212146781f3794393686399e 676 Pfam PF07715 TonB-dependent Receptor Plug Domain 125 237 9.4E-5 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS12205 52c8480e212146781f3794393686399e 676 SUPERFAMILY SSF49452 28 110 1.14E-9 T 28-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 MKLM6_RS12205 52c8480e212146781f3794393686399e 676 SUPERFAMILY SSF56935 125 564 6.72E-38 T 28-03-2018 MKLM6_RS12205 52c8480e212146781f3794393686399e 676 SUPERFAMILY SSF56935 608 666 6.72E-38 T 28-03-2018 MKLM6_RS12205 52c8480e212146781f3794393686399e 676 Pfam PF00593 TonB dependent receptor 381 665 9.3E-10 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS12205 52c8480e212146781f3794393686399e 676 Gene3D G3DSA:2.60.40.1120 30 130 2.5E-10 T 28-03-2018 MKLM6_RS12205 52c8480e212146781f3794393686399e 676 Gene3D G3DSA:2.170.130.10 131 241 3.7E-7 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS12205 52c8480e212146781f3794393686399e 676 Gene3D G3DSA:2.40.170.20 242 667 8.0E-28 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS12205 52c8480e212146781f3794393686399e 676 Pfam PF13620 Carboxypeptidase regulatory-like domain 31 109 6.5E-13 T 28-03-2018 MKLM6_RS06835 52bd9be4bdc03c58265284cfaa5d9d1e 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 2.8E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS06835 52bd9be4bdc03c58265284cfaa5d9d1e 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 2.8E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS06835 52bd9be4bdc03c58265284cfaa5d9d1e 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 2.8E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS06835 52bd9be4bdc03c58265284cfaa5d9d1e 242 SUPERFAMILY SSF51735 3 241 5.22E-85 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS06835 52bd9be4bdc03c58265284cfaa5d9d1e 242 Gene3D G3DSA:3.40.50.720 3 241 8.1E-75 T 28-03-2018 MKLM6_RS06835 52bd9be4bdc03c58265284cfaa5d9d1e 242 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 180 2.0E-4 T 28-03-2018 MKLM6_RS06835 52bd9be4bdc03c58265284cfaa5d9d1e 242 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 6 240 5.4E-101 T 28-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MKLM6_RS06835 52bd9be4bdc03c58265284cfaa5d9d1e 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 2.0E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS06835 52bd9be4bdc03c58265284cfaa5d9d1e 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 2.0E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS06835 52bd9be4bdc03c58265284cfaa5d9d1e 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.0E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS06835 52bd9be4bdc03c58265284cfaa5d9d1e 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 2.0E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS06835 52bd9be4bdc03c58265284cfaa5d9d1e 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 2.0E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS06835 52bd9be4bdc03c58265284cfaa5d9d1e 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 2.0E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS06835 52bd9be4bdc03c58265284cfaa5d9d1e 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MKLM6_RS06835 52bd9be4bdc03c58265284cfaa5d9d1e 242 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 239 1.7E-64 T 28-03-2018 MKLM6_RS04945 a79c5f1b4279b06447590f862e71d961 490 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 56 63 - T 28-03-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 MKLM6_RS04945 a79c5f1b4279b06447590f862e71d961 490 Gene3D G3DSA:3.40.50.1980 25 178 1.1E-50 T 28-03-2018 MKLM6_RS04945 a79c5f1b4279b06447590f862e71d961 490 Gene3D G3DSA:3.40.50.1980 291 371 5.3E-24 T 28-03-2018 MKLM6_RS04945 a79c5f1b4279b06447590f862e71d961 490 Gene3D G3DSA:3.40.50.1980 372 460 4.0E-19 T 28-03-2018 MKLM6_RS04945 a79c5f1b4279b06447590f862e71d961 490 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 38 446 1.7E-108 T 28-03-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 MKLM6_RS04945 a79c5f1b4279b06447590f862e71d961 490 Gene3D G3DSA:3.40.50.1980 188 290 5.2E-27 T 28-03-2018 MKLM6_RS04945 a79c5f1b4279b06447590f862e71d961 490 TIGRFAM TIGR01283 nifE: nitrogenase MoFe cofactor biosynthesis protein NifE 5 460 1.3E-212 T 28-03-2018 IPR005973 Nitrogenase MoFe cofactor biosynthesis protein NifE GO:0006461|GO:0009399 MKLM6_RS04945 a79c5f1b4279b06447590f862e71d961 490 ProSitePatterns PS00090 Nitrogenases component 1 alpha and beta subunits signature 2. 123 137 - T 28-03-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 MKLM6_RS04945 a79c5f1b4279b06447590f862e71d961 490 SUPERFAMILY SSF53807 8 458 4.77E-137 T 28-03-2018 MKLM6_RS12805 12d544c226a43d5df128d2a1da918833 402 SUPERFAMILY SSF55073 241 400 1.1E-46 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS12805 12d544c226a43d5df128d2a1da918833 402 SMART SM00267 226 400 2.8E-60 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS12805 12d544c226a43d5df128d2a1da918833 402 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 235 397 1.2E-48 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS12805 12d544c226a43d5df128d2a1da918833 402 Pfam PF11845 Protein of unknown function (DUF3365) 3 182 8.2E-31 T 28-03-2018 IPR021796 Protein of unknown function DUF3365 MKLM6_RS12805 12d544c226a43d5df128d2a1da918833 402 Gene3D G3DSA:3.30.70.270 229 402 3.6E-51 T 28-03-2018 MKLM6_RS12805 12d544c226a43d5df128d2a1da918833 402 Pfam PF00990 Diguanylate cyclase, GGDEF domain 236 396 3.1E-48 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS19375 8adf500dd5792344d1766d379d269018 119 Pfam PF01219 Prokaryotic diacylglycerol kinase 18 118 8.6E-34 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 MKLM6_RS19375 8adf500dd5792344d1766d379d269018 119 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 71 82 - T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 MKLM6_RS19375 8adf500dd5792344d1766d379d269018 119 Gene3D G3DSA:1.10.3830.10 8 119 2.1E-39 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 MKLM6_RS03715 b8982270e474abc1764c3aa525f8df14 359 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 353 1.3E-139 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MKLM6_RS03715 b8982270e474abc1764c3aa525f8df14 359 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 MKLM6_RS03715 b8982270e474abc1764c3aa525f8df14 359 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 352 4.2E-159 T 28-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 MKLM6_RS03715 b8982270e474abc1764c3aa525f8df14 359 Gene3D G3DSA:3.40.718.10 1 359 3.8E-130 T 28-03-2018 MKLM6_RS03715 b8982270e474abc1764c3aa525f8df14 359 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 357 52.283 T 28-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 MKLM6_RS03715 b8982270e474abc1764c3aa525f8df14 359 SMART SM01329 4 353 2.7E-210 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MKLM6_RS03715 b8982270e474abc1764c3aa525f8df14 359 SUPERFAMILY SSF53659 1 357 1.53E-126 T 28-03-2018 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 Gene3D G3DSA:3.30.70.1320 138 196 0.032 T 28-03-2018 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 Gene3D G3DSA:3.30.70.1320 745 822 0.12 T 28-03-2018 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 Gene3D G3DSA:3.30.70.1430 41 137 3.2E-22 T 28-03-2018 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 SUPERFAMILY SSF82693 267 323 1.57E-22 T 28-03-2018 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 SUPERFAMILY SSF82693 135 181 1.57E-22 T 28-03-2018 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 Pfam PF00873 AcrB/AcrD/AcrF family 4 1005 6.8E-260 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 Gene3D G3DSA:3.30.2090.10 197 265 1.1E-12 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 SUPERFAMILY SSF82714 183 265 1.27E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 SUPERFAMILY SSF82714 703 785 1.1E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 2.1E-65 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.1E-65 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 2.1E-65 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 2.1E-65 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 2.1E-65 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 2.1E-65 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 PRINTS PR00702 Acriflavin resistance protein family signature 540 557 2.1E-65 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 2.1E-65 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 Gene3D G3DSA:1.20.1640.10 823 1007 4.5E-40 T 28-03-2018 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 Gene3D G3DSA:1.20.1640.10 266 491 1.5E-44 T 28-03-2018 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 SUPERFAMILY SSF82693 553 651 2.88E-12 T 28-03-2018 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 SUPERFAMILY SSF82866 810 1005 1.44E-43 T 28-03-2018 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 Gene3D G3DSA:3.30.70.1430 555 650 0.0014 T 28-03-2018 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 SUPERFAMILY SSF82693 786 835 2.96E-20 T 28-03-2018 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 SUPERFAMILY SSF82693 651 699 2.96E-20 T 28-03-2018 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 SUPERFAMILY SSF82866 289 488 1.57E-47 T 28-03-2018 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 SUPERFAMILY SSF82693 42 134 1.94E-19 T 28-03-2018 MKLM6_RS10845 61ed5116eb4d771d9c8951d0ed95316e 1017 Gene3D G3DSA:3.30.70.1440 651 744 1.4E-16 T 28-03-2018 MKLM6_RS07685 02bbd743ff80d069427da5667718e7e8 76 SMART SM00966 7 45 0.003 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MKLM6_RS07685 02bbd743ff80d069427da5667718e7e8 76 Gene3D G3DSA:2.10.260.10 1 76 1.9E-11 T 28-03-2018 MKLM6_RS07685 02bbd743ff80d069427da5667718e7e8 76 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 43 5.8E-11 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MKLM6_RS07685 02bbd743ff80d069427da5667718e7e8 76 SUPERFAMILY SSF89447 4 67 1.05E-12 T 28-03-2018 MKLM6_RS03750 0c0f17bf794f05519ed7a908c9547161 526 Pfam PF02239 Cytochrome D1 heme domain 166 507 1.8E-48 T 28-03-2018 MKLM6_RS03750 0c0f17bf794f05519ed7a908c9547161 526 SUPERFAMILY SSF46626 28 109 1.32E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS03750 0c0f17bf794f05519ed7a908c9547161 526 SUPERFAMILY SSF51004 113 506 1.7E-60 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain MKLM6_RS03750 0c0f17bf794f05519ed7a908c9547161 526 PRINTS PR00605 Class IC cytochrome C signature 80 102 4.9E-5 T 28-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 MKLM6_RS03750 0c0f17bf794f05519ed7a908c9547161 526 PRINTS PR00605 Class IC cytochrome C signature 39 50 4.9E-5 T 28-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 MKLM6_RS03750 0c0f17bf794f05519ed7a908c9547161 526 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 31 102 8.3E-11 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS03750 0c0f17bf794f05519ed7a908c9547161 526 Gene3D G3DSA:2.140.10.20 123 514 1.3E-49 T 28-03-2018 MKLM6_RS03750 0c0f17bf794f05519ed7a908c9547161 526 Gene3D G3DSA:1.10.760.10 34 122 3.0E-13 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS00760 1f8da9ca76188ecd7dffbd8648f137d7 196 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 6 180 4.1E-56 T 28-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG MKLM6_RS00760 1f8da9ca76188ecd7dffbd8648f137d7 196 Gene3D G3DSA:3.40.50.450 1 195 2.5E-60 T 28-03-2018 MKLM6_RS00760 1f8da9ca76188ecd7dffbd8648f137d7 196 SUPERFAMILY SSF102405 3 177 7.17E-62 T 28-03-2018 MKLM6_RS00760 1f8da9ca76188ecd7dffbd8648f137d7 196 Pfam PF03641 Possible lysine decarboxylase 49 177 5.4E-43 T 28-03-2018 IPR031100 LOG family MKLM6_RS04180 d3a31832cc1e1cf1e12ef28f826450af 139 Pfam PF01850 PIN domain 2 127 1.8E-12 T 28-03-2018 IPR002716 PIN domain MKLM6_RS04180 d3a31832cc1e1cf1e12ef28f826450af 139 Gene3D G3DSA:3.40.50.1010 1 139 2.2E-24 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS04180 d3a31832cc1e1cf1e12ef28f826450af 139 SUPERFAMILY SSF88723 1 137 7.01E-26 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS14935 e0ad530f1df899bec22fd85908112b24 254 Gene3D G3DSA:3.30.540.10 3 147 4.2E-43 T 28-03-2018 MKLM6_RS14935 e0ad530f1df899bec22fd85908112b24 254 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 209 223 - T 28-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 MKLM6_RS14935 e0ad530f1df899bec22fd85908112b24 254 PRINTS PR01959 SuhB family inositol monophosphatase signature 196 208 3.0E-8 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 MKLM6_RS14935 e0ad530f1df899bec22fd85908112b24 254 PRINTS PR01959 SuhB family inositol monophosphatase signature 102 121 3.0E-8 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 MKLM6_RS14935 e0ad530f1df899bec22fd85908112b24 254 PRINTS PR01959 SuhB family inositol monophosphatase signature 17 39 3.0E-8 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 MKLM6_RS14935 e0ad530f1df899bec22fd85908112b24 254 Pfam PF00459 Inositol monophosphatase family 9 243 2.4E-56 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MKLM6_RS14935 e0ad530f1df899bec22fd85908112b24 254 SUPERFAMILY SSF56655 5 253 2.09E-74 T 28-03-2018 MKLM6_RS14935 e0ad530f1df899bec22fd85908112b24 254 Gene3D G3DSA:3.40.190.80 148 254 4.1E-31 T 28-03-2018 MKLM6_RS14935 e0ad530f1df899bec22fd85908112b24 254 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 79 92 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site MKLM6_RS14935 e0ad530f1df899bec22fd85908112b24 254 PRINTS PR00377 Inositol monophosphatase superfamily signature 175 196 1.1E-40 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MKLM6_RS14935 e0ad530f1df899bec22fd85908112b24 254 PRINTS PR00377 Inositol monophosphatase superfamily signature 206 230 1.1E-40 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MKLM6_RS14935 e0ad530f1df899bec22fd85908112b24 254 PRINTS PR00377 Inositol monophosphatase superfamily signature 128 151 1.1E-40 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MKLM6_RS14935 e0ad530f1df899bec22fd85908112b24 254 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 1.1E-40 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MKLM6_RS14935 e0ad530f1df899bec22fd85908112b24 254 PRINTS PR00377 Inositol monophosphatase superfamily signature 79 95 1.1E-40 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MKLM6_RS14935 e0ad530f1df899bec22fd85908112b24 254 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 1.1E-40 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MKLM6_RS04610 bae8924dc0967e78b9a12507e7f77b10 205 SUPERFAMILY SSF52833 2 100 8.4E-31 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS04610 bae8924dc0967e78b9a12507e7f77b10 205 Gene3D G3DSA:3.40.30.10 1 117 1.7E-28 T 28-03-2018 MKLM6_RS04610 bae8924dc0967e78b9a12507e7f77b10 205 SUPERFAMILY SSF82657 114 194 4.32E-18 T 28-03-2018 IPR002634 BolA protein MKLM6_RS04610 bae8924dc0967e78b9a12507e7f77b10 205 Pfam PF01722 BolA-like protein 137 186 1.7E-8 T 28-03-2018 IPR002634 BolA protein MKLM6_RS04610 bae8924dc0967e78b9a12507e7f77b10 205 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 4 99 7.2E-36 T 28-03-2018 IPR004480 Monothiol glutaredoxin-related MKLM6_RS04610 bae8924dc0967e78b9a12507e7f77b10 205 Pfam PF00462 Glutaredoxin 16 80 4.0E-18 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 MKLM6_RS04610 bae8924dc0967e78b9a12507e7f77b10 205 Gene3D G3DSA:3.30.300.90 118 199 4.9E-15 T 28-03-2018 MKLM6_RS06720 87d313efc382425f42a7bcd4b17b9ad3 100 SUPERFAMILY SSF54111 1 99 1.1E-47 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MKLM6_RS06720 87d313efc382425f42a7bcd4b17b9ad3 100 Gene3D G3DSA:3.30.280.10 2 99 3.1E-49 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MKLM6_RS06720 87d313efc382425f42a7bcd4b17b9ad3 100 Pfam PF00547 Urease, gamma subunit 1 99 1.6E-48 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MKLM6_RS06720 87d313efc382425f42a7bcd4b17b9ad3 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 35.774 T 28-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MKLM6_RS06720 87d313efc382425f42a7bcd4b17b9ad3 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 99 7.0E-56 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MKLM6_RS06720 87d313efc382425f42a7bcd4b17b9ad3 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 6.0E-42 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MKLM6_RS06720 87d313efc382425f42a7bcd4b17b9ad3 100 PIRSF PIRSF001223 1 100 1.1E-51 T 28-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MKLM6_RS02730 f484c3f3310d669c8808a0506dd12271 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 1.4E-19 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MKLM6_RS02730 f484c3f3310d669c8808a0506dd12271 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 1.4E-19 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MKLM6_RS02730 f484c3f3310d669c8808a0506dd12271 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 1.4E-19 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MKLM6_RS02730 f484c3f3310d669c8808a0506dd12271 89 PIRSF PIRSF004669 1 89 2.0E-31 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MKLM6_RS02730 f484c3f3310d669c8808a0506dd12271 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 4.0E-28 T 28-03-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 MKLM6_RS02730 f484c3f3310d669c8808a0506dd12271 89 Pfam PF01313 Bacterial export proteins, family 3 6 78 1.4E-27 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MKLM6_RS08025 81196bb3fed79c409d153c3b5a8def42 711 Gene3D G3DSA:3.40.30.10 582 692 4.7E-8 T 28-03-2018 MKLM6_RS08025 81196bb3fed79c409d153c3b5a8def42 711 SUPERFAMILY SSF52833 607 706 1.62E-14 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS08025 81196bb3fed79c409d153c3b5a8def42 711 Pfam PF13899 Thioredoxin-like 604 685 2.0E-14 T 28-03-2018 MKLM6_RS08025 81196bb3fed79c409d153c3b5a8def42 711 Pfam PF11412 Disulphide bond corrector protein DsbC 35 155 3.7E-21 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain MKLM6_RS08025 81196bb3fed79c409d153c3b5a8def42 711 Gene3D G3DSA:2.60.40.1250 21 165 2.0E-9 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain MKLM6_RS19030 f48a1deda0db76caea1b54d6907bd5a6 256 Pfam PF05673 Protein of unknown function (DUF815) 6 249 2.8E-100 T 28-03-2018 IPR008533 Domain of unknown function DUF815 MKLM6_RS19030 f48a1deda0db76caea1b54d6907bd5a6 256 Gene3D G3DSA:3.40.50.300 10 172 1.7E-15 T 28-03-2018 MKLM6_RS19030 f48a1deda0db76caea1b54d6907bd5a6 256 SUPERFAMILY SSF52540 13 164 1.33E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS19030 f48a1deda0db76caea1b54d6907bd5a6 256 SMART SM00382 55 176 9.7E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS10435 999b1268687fad7154c65eb2597e40e2 3457 Pfam PF05860 haemagglutination activity domain 60 157 2.0E-18 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MKLM6_RS10435 999b1268687fad7154c65eb2597e40e2 3457 Gene3D G3DSA:2.160.20.10 1380 1714 2.0E-4 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS10435 999b1268687fad7154c65eb2597e40e2 3457 SMART SM00912 41 159 1.6E-34 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MKLM6_RS10435 999b1268687fad7154c65eb2597e40e2 3457 Gene3D G3DSA:2.160.20.10 342 624 0.3 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS10435 999b1268687fad7154c65eb2597e40e2 3457 Gene3D G3DSA:2.160.20.10 47 341 1.5E-36 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS10435 999b1268687fad7154c65eb2597e40e2 3457 Gene3D G3DSA:2.160.20.10 901 1161 0.0025 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS10435 999b1268687fad7154c65eb2597e40e2 3457 Gene3D G3DSA:2.160.20.10 625 894 1.4E-7 T 28-03-2018 IPR012334 Pectin lyase fold MKLM6_RS10435 999b1268687fad7154c65eb2597e40e2 3457 SUPERFAMILY SSF51126 220 333 7.53E-33 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS10435 999b1268687fad7154c65eb2597e40e2 3457 SUPERFAMILY SSF51126 60 163 7.53E-33 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS10435 999b1268687fad7154c65eb2597e40e2 3457 SUPERFAMILY SSF51126 386 411 7.53E-33 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS10435 999b1268687fad7154c65eb2597e40e2 3457 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 81 156 1.7E-22 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MKLM6_RS10435 999b1268687fad7154c65eb2597e40e2 3457 Pfam PF12545 Filamentous haemagglutinin family outer membrane protein 3281 3384 5.4E-32 T 28-03-2018 IPR021026 Filamentous haemagglutinin family outer membrane protein, domain of unknown function DUF3739 MKLM6_RS10800 b91120e25664ad53b0d41e86eaa1d30f 293 SUPERFAMILY SSF51735 4 173 2.22E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS10800 b91120e25664ad53b0d41e86eaa1d30f 293 Gene3D G3DSA:1.10.3660.10 185 293 6.5E-32 T 28-03-2018 MKLM6_RS10800 b91120e25664ad53b0d41e86eaa1d30f 293 Gene3D G3DSA:3.40.50.720 2 175 4.3E-34 T 28-03-2018 MKLM6_RS10800 b91120e25664ad53b0d41e86eaa1d30f 293 Pfam PF02153 Prephenate dehydrogenase 17 275 3.3E-68 T 28-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 MKLM6_RS10800 b91120e25664ad53b0d41e86eaa1d30f 293 SUPERFAMILY SSF48179 178 286 4.65E-34 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MKLM6_RS17090 cd8923205634bc5c1dc187cebcd08439 311 PRINTS PR00885 Bacterial general secretion pathway protein H signature 123 137 1.4E-5 T 28-03-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 MKLM6_RS17090 cd8923205634bc5c1dc187cebcd08439 311 PRINTS PR00885 Bacterial general secretion pathway protein H signature 255 270 1.4E-5 T 28-03-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 MKLM6_RS17090 cd8923205634bc5c1dc187cebcd08439 311 PRINTS PR00885 Bacterial general secretion pathway protein H signature 108 122 1.4E-5 T 28-03-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 MKLM6_RS17090 cd8923205634bc5c1dc187cebcd08439 311 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 110 133 1.9E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS17090 cd8923205634bc5c1dc187cebcd08439 311 Gene3D G3DSA:3.30.700.10 113 233 4.4E-12 T 28-03-2018 MKLM6_RS17090 cd8923205634bc5c1dc187cebcd08439 311 SUPERFAMILY SSF54523 113 170 1.1E-11 T 28-03-2018 MKLM6_RS17090 cd8923205634bc5c1dc187cebcd08439 311 Pfam PF07963 Prokaryotic N-terminal methylation motif 109 132 8.3E-7 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS17090 cd8923205634bc5c1dc187cebcd08439 311 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 111 131 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS12400 1c3eeeffe70ba51a28f763e8f35da9b9 390 Gene3D G3DSA:1.20.1250.20 2 181 9.7E-11 T 28-03-2018 MKLM6_RS12400 1c3eeeffe70ba51a28f763e8f35da9b9 390 Gene3D G3DSA:1.20.1250.20 189 388 1.1E-7 T 28-03-2018 MKLM6_RS12400 1c3eeeffe70ba51a28f763e8f35da9b9 390 SUPERFAMILY SSF103473 5 381 3.01E-19 T 28-03-2018 IPR020846 Major facilitator superfamily domain MKLM6_RS12400 1c3eeeffe70ba51a28f763e8f35da9b9 390 Pfam PF07690 Major Facilitator Superfamily 8 344 1.7E-9 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MKLM6_RS20585 efe46d04f40b37c37370f9578f9d404e 252 SUPERFAMILY SSF141571 131 240 7.98E-25 T 28-03-2018 MKLM6_RS20585 efe46d04f40b37c37370f9578f9d404e 252 SUPERFAMILY SSF141571 43 144 1.02E-20 T 28-03-2018 MKLM6_RS20585 efe46d04f40b37c37370f9578f9d404e 252 Pfam PF00805 Pentapeptide repeats (8 copies) 55 92 3.9E-7 T 28-03-2018 IPR001646 Pentapeptide repeat MKLM6_RS20585 efe46d04f40b37c37370f9578f9d404e 252 Pfam PF00805 Pentapeptide repeats (8 copies) 199 238 3.8E-11 T 28-03-2018 IPR001646 Pentapeptide repeat MKLM6_RS20585 efe46d04f40b37c37370f9578f9d404e 252 Pfam PF00805 Pentapeptide repeats (8 copies) 159 196 6.6E-10 T 28-03-2018 IPR001646 Pentapeptide repeat MKLM6_RS20585 efe46d04f40b37c37370f9578f9d404e 252 Gene3D G3DSA:2.160.20.80 17 153 8.1E-23 T 28-03-2018 MKLM6_RS20585 efe46d04f40b37c37370f9578f9d404e 252 Gene3D G3DSA:2.160.10.20 194 243 1.0E-15 T 28-03-2018 MKLM6_RS20585 efe46d04f40b37c37370f9578f9d404e 252 Gene3D G3DSA:3.30.1120.50 156 193 5.5E-14 T 28-03-2018 MKLM6_RS20860 91622c99021cdf770d55b2a5b2f16606 282 Hamap MF_00697 UPF0276 protein . 11 279 44.512 T 28-03-2018 IPR007801 Uncharacterised protein family UPF0276 MKLM6_RS20860 91622c99021cdf770d55b2a5b2f16606 282 SUPERFAMILY SSF51658 34 261 8.49E-15 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MKLM6_RS20860 91622c99021cdf770d55b2a5b2f16606 282 Pfam PF05114 Protein of unknown function (DUF692) 10 272 1.0E-103 T 28-03-2018 IPR007801 Uncharacterised protein family UPF0276 MKLM6_RS20860 91622c99021cdf770d55b2a5b2f16606 282 Gene3D G3DSA:3.20.20.150 6 282 3.2E-81 T 28-03-2018 MKLM6_RS16165 313bf53818c22b62d76b2eed8dfab7cb 359 Gene3D G3DSA:2.40.50.100 13 62 3.4E-6 T 28-03-2018 MKLM6_RS16165 313bf53818c22b62d76b2eed8dfab7cb 359 Gene3D G3DSA:2.40.50.100 63 184 3.0E-18 T 28-03-2018 MKLM6_RS16165 313bf53818c22b62d76b2eed8dfab7cb 359 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 20 343 7.9E-72 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MKLM6_RS16165 313bf53818c22b62d76b2eed8dfab7cb 359 SUPERFAMILY SSF111369 35 246 1.19E-22 T 28-03-2018 MKLM6_RS16165 313bf53818c22b62d76b2eed8dfab7cb 359 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 49 246 2.9E-19 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MKLM6_RS14840 86f7bc35fcdf3ff3c0c53366ea68a84b 104 Gene3D G3DSA:3.40.250.10 4 103 1.3E-22 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS14840 86f7bc35fcdf3ff3c0c53366ea68a84b 104 Pfam PF00581 Rhodanese-like domain 10 98 3.6E-16 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS14840 86f7bc35fcdf3ff3c0c53366ea68a84b 104 SMART SM00450 7 102 9.2E-17 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS14840 86f7bc35fcdf3ff3c0c53366ea68a84b 104 SUPERFAMILY SSF52821 1 99 1.24E-23 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS13575 693b7ab8fb0e164814a15b89b18d0ab6 161 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 6 151 24.611 T 28-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 MKLM6_RS13575 693b7ab8fb0e164814a15b89b18d0ab6 161 Pfam PF17384 RimP C-terminal SH3 domain 87 150 2.7E-14 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal MKLM6_RS13575 693b7ab8fb0e164814a15b89b18d0ab6 161 Gene3D G3DSA:3.30.300.70 1 80 7.7E-28 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal MKLM6_RS13575 693b7ab8fb0e164814a15b89b18d0ab6 161 Gene3D G3DSA:2.30.30.180 88 148 7.1E-15 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal MKLM6_RS13575 693b7ab8fb0e164814a15b89b18d0ab6 161 Pfam PF02576 RimP N-terminal domain 11 83 2.3E-28 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal MKLM6_RS13575 693b7ab8fb0e164814a15b89b18d0ab6 161 SUPERFAMILY SSF75420 5 83 2.75E-24 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal MKLM6_RS13575 693b7ab8fb0e164814a15b89b18d0ab6 161 SUPERFAMILY SSF74942 84 152 3.92E-15 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal MKLM6_RS11375 62c3886f3364313868c376f59847fe27 405 Pfam PF00482 Type II secretion system (T2SS), protein F 73 194 3.5E-30 T 28-03-2018 IPR018076 Type II secretion system F domain MKLM6_RS11375 62c3886f3364313868c376f59847fe27 405 Pfam PF00482 Type II secretion system (T2SS), protein F 274 395 7.8E-29 T 28-03-2018 IPR018076 Type II secretion system F domain MKLM6_RS11375 62c3886f3364313868c376f59847fe27 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 369 383 4.2E-20 T 28-03-2018 IPR003004 GspF/PilC family MKLM6_RS11375 62c3886f3364313868c376f59847fe27 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 385 404 4.2E-20 T 28-03-2018 IPR003004 GspF/PilC family MKLM6_RS11375 62c3886f3364313868c376f59847fe27 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 66 78 4.2E-20 T 28-03-2018 IPR003004 GspF/PilC family MKLM6_RS11375 62c3886f3364313868c376f59847fe27 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 166 194 4.2E-20 T 28-03-2018 IPR003004 GspF/PilC family MKLM6_RS18995 638badd19c995e918649474b20c2375e 221 SUPERFAMILY SSF52242 79 218 3.01E-30 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MKLM6_RS18995 638badd19c995e918649474b20c2375e 221 Gene3D G3DSA:3.40.50.280 72 221 3.0E-26 T 28-03-2018 MKLM6_RS18995 638badd19c995e918649474b20c2375e 221 Pfam PF02310 B12 binding domain 92 208 1.0E-18 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MKLM6_RS11735 ba766329413200f48edc5a17a65448ea 108 Pfam PF00403 Heavy-metal-associated domain 38 98 3.6E-15 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MKLM6_RS11735 ba766329413200f48edc5a17a65448ea 108 Gene3D G3DSA:3.30.70.100 32 106 9.4E-24 T 28-03-2018 MKLM6_RS11735 ba766329413200f48edc5a17a65448ea 108 SUPERFAMILY SSF55008 30 101 6.28E-22 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MKLM6_RS12075 7789534d5150afaf288e42f6a16e0492 220 Gene3D G3DSA:3.40.50.2300 1 117 6.8E-35 T 28-03-2018 MKLM6_RS12075 7789534d5150afaf288e42f6a16e0492 220 Pfam PF00072 Response regulator receiver domain 4 113 2.5E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS12075 7789534d5150afaf288e42f6a16e0492 220 SUPERFAMILY SSF52172 1 174 3.56E-38 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS12075 7789534d5150afaf288e42f6a16e0492 220 SMART SM00862 145 216 2.2E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS12075 7789534d5150afaf288e42f6a16e0492 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 216 2.4E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS12075 7789534d5150afaf288e42f6a16e0492 220 Gene3D G3DSA:1.10.10.10 118 220 6.0E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS12075 7789534d5150afaf288e42f6a16e0492 220 SMART SM00448 1 112 2.0E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS21295 d235a751ac146e7c3b5e32f4d841ff21 158 SUPERFAMILY SSF54523 11 101 1.14E-17 T 28-03-2018 MKLM6_RS21295 d235a751ac146e7c3b5e32f4d841ff21 158 Pfam PF07963 Prokaryotic N-terminal methylation motif 8 30 5.3E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS21295 d235a751ac146e7c3b5e32f4d841ff21 158 Gene3D G3DSA:3.30.700.10 11 143 5.7E-16 T 28-03-2018 MKLM6_RS21295 d235a751ac146e7c3b5e32f4d841ff21 158 PRINTS PR00813 Bacterial general secretion pathway protein G signature 10 35 4.6E-7 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 MKLM6_RS21295 d235a751ac146e7c3b5e32f4d841ff21 158 PRINTS PR00813 Bacterial general secretion pathway protein G signature 46 64 4.6E-7 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 MKLM6_RS21295 d235a751ac146e7c3b5e32f4d841ff21 158 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 31 5.5E-5 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS12985 e2b01e61d17b51a61cd558925aab8be8 482 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 15 473 7.5E-197 T 28-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 MKLM6_RS12985 e2b01e61d17b51a61cd558925aab8be8 482 SUPERFAMILY SSF101960 36 81 1.11E-141 T 28-03-2018 MKLM6_RS12985 e2b01e61d17b51a61cd558925aab8be8 482 SUPERFAMILY SSF101960 108 479 1.11E-141 T 28-03-2018 MKLM6_RS12985 e2b01e61d17b51a61cd558925aab8be8 482 Pfam PF01458 Uncharacterized protein family (UPF0051) 220 453 1.0E-69 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 MKLM6_RS01450 847afbb1c775e2d0f684d23401e47832 607 Pfam PF07715 TonB-dependent Receptor Plug Domain 43 149 4.1E-26 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS01450 847afbb1c775e2d0f684d23401e47832 607 SUPERFAMILY SSF56935 31 607 5.19E-108 T 28-03-2018 MKLM6_RS01450 847afbb1c775e2d0f684d23401e47832 607 Gene3D G3DSA:2.40.170.20 158 606 1.5E-59 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS01450 847afbb1c775e2d0f684d23401e47832 607 Gene3D G3DSA:2.170.130.10 20 156 1.6E-33 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS01450 847afbb1c775e2d0f684d23401e47832 607 Pfam PF00593 TonB dependent receptor 195 606 2.6E-35 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS12040 01596031add2249d20eff9c3721c6beb 120 Pfam PF03259 Roadblock/LC7 domain 15 96 4.8E-16 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain MKLM6_RS12040 01596031add2249d20eff9c3721c6beb 120 SMART SM00960 6 96 6.9E-24 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain MKLM6_RS12040 01596031add2249d20eff9c3721c6beb 120 Gene3D G3DSA:3.30.450.30 1 120 1.0E-25 T 28-03-2018 MKLM6_RS12040 01596031add2249d20eff9c3721c6beb 120 SUPERFAMILY SSF103196 4 120 1.64E-30 T 28-03-2018 MKLM6_RS19825 04d58c957e00d074bf69158248d098fa 364 Gene3D G3DSA:3.40.630.30 5 147 1.6E-9 T 28-03-2018 MKLM6_RS19825 04d58c957e00d074bf69158248d098fa 364 SUPERFAMILY SSF55729 208 290 5.02E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS19825 04d58c957e00d074bf69158248d098fa 364 SUPERFAMILY SSF55729 13 153 5.02E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS19825 04d58c957e00d074bf69158248d098fa 364 Gene3D G3DSA:3.40.630.30 186 321 2.3E-4 T 28-03-2018 MKLM6_RS20385 bac3bcffa2d527a1acc5c84a6481176f 276 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 4 274 6.1E-93 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MKLM6_RS20385 bac3bcffa2d527a1acc5c84a6481176f 276 Gene3D G3DSA:3.10.310.10 1 125 2.4E-49 T 28-03-2018 MKLM6_RS20385 bac3bcffa2d527a1acc5c84a6481176f 276 Pfam PF01678 Diaminopimelate epimerase 154 269 9.6E-27 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MKLM6_RS20385 bac3bcffa2d527a1acc5c84a6481176f 276 Pfam PF01678 Diaminopimelate epimerase 5 124 9.5E-34 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MKLM6_RS20385 bac3bcffa2d527a1acc5c84a6481176f 276 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 276 39.051 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MKLM6_RS20385 bac3bcffa2d527a1acc5c84a6481176f 276 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 66 80 - T 28-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MKLM6_RS20385 bac3bcffa2d527a1acc5c84a6481176f 276 Gene3D G3DSA:3.10.310.10 126 263 6.7E-50 T 28-03-2018 MKLM6_RS20385 bac3bcffa2d527a1acc5c84a6481176f 276 SUPERFAMILY SSF54506 3 275 1.96E-50 T 28-03-2018 MKLM6_RS15475 3ce486d17290a67cd77a4a3552e5b738 525 Gene3D G3DSA:1.20.1250.20 5 204 1.1E-28 T 28-03-2018 MKLM6_RS15475 3ce486d17290a67cd77a4a3552e5b738 525 Gene3D G3DSA:1.20.1250.20 264 516 1.6E-16 T 28-03-2018 MKLM6_RS15475 3ce486d17290a67cd77a4a3552e5b738 525 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 38 497 2.7E-88 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 MKLM6_RS15475 3ce486d17290a67cd77a4a3552e5b738 525 Pfam PF07690 Major Facilitator Superfamily 24 414 6.5E-38 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MKLM6_RS15475 3ce486d17290a67cd77a4a3552e5b738 525 SUPERFAMILY SSF103473 6 198 2.88E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain MKLM6_RS15475 3ce486d17290a67cd77a4a3552e5b738 525 SUPERFAMILY SSF103473 253 424 2.88E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain MKLM6_RS15475 3ce486d17290a67cd77a4a3552e5b738 525 SUPERFAMILY SSF103473 476 502 2.88E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain MKLM6_RS20605 6bca72e621b20e06a066a0ea9bc95259 88 Pfam PF13711 Domain of unknown function (DUF4160) 9 72 9.6E-26 T 28-03-2018 IPR025427 Protein of unknown function DUF4160 MKLM6_RS08740 3c88bfda89fca65d42841a28b9758549 143 PIRSF PIRSF006173 1 142 1.4E-58 T 28-03-2018 IPR008228 Uncharacterised conserved protein UCP006173 MKLM6_RS08740 3c88bfda89fca65d42841a28b9758549 143 Hamap MF_00676 UPF0260 protein YcgN [ycgN]. 1 142 36.799 T 28-03-2018 IPR008228 Uncharacterised conserved protein UCP006173 MKLM6_RS08740 3c88bfda89fca65d42841a28b9758549 143 Pfam PF03692 Putative zinc- or iron-chelating domain 21 89 1.4E-6 T 28-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein MKLM6_RS15265 f93cacb720683d6d782f0dcdece4a8c1 87 SUPERFAMILY SSF46689 8 86 2.69E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS15265 f93cacb720683d6d782f0dcdece4a8c1 87 PRINTS PR01591 DNA-binding protein FIS signature 15 31 3.8E-8 T 28-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 MKLM6_RS15265 f93cacb720683d6d782f0dcdece4a8c1 87 PRINTS PR01591 DNA-binding protein FIS signature 31 46 3.8E-8 T 28-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 MKLM6_RS15265 f93cacb720683d6d782f0dcdece4a8c1 87 PRINTS PR01591 DNA-binding protein FIS signature 46 58 3.8E-8 T 28-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 MKLM6_RS15265 f93cacb720683d6d782f0dcdece4a8c1 87 Pfam PF02954 Bacterial regulatory protein, Fis family 44 84 8.2E-15 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS15265 f93cacb720683d6d782f0dcdece4a8c1 87 PIRSF PIRSF002097 2 87 1.1E-29 T 28-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 MKLM6_RS15265 f93cacb720683d6d782f0dcdece4a8c1 87 Gene3D G3DSA:1.10.10.60 4 87 8.2E-20 T 28-03-2018 MKLM6_RS15265 f93cacb720683d6d782f0dcdece4a8c1 87 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 50 67 1.1E-10 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS15265 f93cacb720683d6d782f0dcdece4a8c1 87 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 67 87 1.1E-10 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS18920 44b325a0125824b7b73553aac8a86946 1071 SUPERFAMILY SSF48208 10 448 5.78E-79 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 MKLM6_RS18920 44b325a0125824b7b73553aac8a86946 1071 Gene3D G3DSA:1.50.10.10 2 342 1.5E-53 T 28-03-2018 MKLM6_RS18920 44b325a0125824b7b73553aac8a86946 1071 Pfam PF00723 Glycosyl hydrolases family 15 9 820 3.1E-129 T 28-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 MKLM6_RS09215 bd443e3c87feb571af82ed4c35f451dc 174 Pfam PF13740 ACT domain 3 75 3.5E-10 T 28-03-2018 MKLM6_RS09215 bd443e3c87feb571af82ed4c35f451dc 174 Gene3D G3DSA:3.30.70.260 87 173 3.9E-9 T 28-03-2018 MKLM6_RS09215 bd443e3c87feb571af82ed4c35f451dc 174 Gene3D G3DSA:3.30.70.260 1 80 4.7E-7 T 28-03-2018 MKLM6_RS09215 bd443e3c87feb571af82ed4c35f451dc 174 SUPERFAMILY SSF55021 89 172 4.16E-9 T 28-03-2018 MKLM6_RS09215 bd443e3c87feb571af82ed4c35f451dc 174 PIRSF PIRSF028103 1 174 1.8E-32 T 28-03-2018 IPR016867 Glycine cleavage system transcriptional repressor GO:0006355 MKLM6_RS09215 bd443e3c87feb571af82ed4c35f451dc 174 SUPERFAMILY SSF55021 3 77 1.75E-7 T 28-03-2018 MKLM6_RS06435 b3683dad303142c037f6c9aa1cf0e859 160 Pfam PF16694 Cytochrome P460 30 156 6.6E-33 T 28-03-2018 IPR032033 Cytochrome P460 MKLM6_RS02100 4047c1d24dd68baf320dde7c60dd6910 148 SUPERFAMILY SSF53098 15 147 1.67E-32 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS02100 4047c1d24dd68baf320dde7c60dd6910 148 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 17 147 8.5E-34 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MKLM6_RS02100 4047c1d24dd68baf320dde7c60dd6910 148 Gene3D G3DSA:3.30.420.140 12 148 3.6E-35 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 MKLM6_RS02100 4047c1d24dd68baf320dde7c60dd6910 148 Pfam PF03652 Holliday junction resolvase 16 147 3.9E-36 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MKLM6_RS02100 4047c1d24dd68baf320dde7c60dd6910 148 SMART SM00732 14 114 2.4E-19 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 MKLM6_RS02100 4047c1d24dd68baf320dde7c60dd6910 148 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 14 148 19.011 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MKLM6_RS01660 ba1c2960c6f96f4dc052691727d513e1 370 SUPERFAMILY SSF111369 60 287 1.16E-21 T 28-03-2018 MKLM6_RS01660 ba1c2960c6f96f4dc052691727d513e1 370 Gene3D G3DSA:1.20.1600.10 19 332 4.7E-25 T 28-03-2018 MKLM6_RS01660 ba1c2960c6f96f4dc052691727d513e1 370 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 81 282 3.7E-15 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MKLM6_RS01660 ba1c2960c6f96f4dc052691727d513e1 370 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 45 367 2.7E-62 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MKLM6_RS18005 8018d0ec0ba021b98b545e5de42554eb 129 TIGRFAM TIGR00208 fliS: flagellar protein FliS 9 126 1.8E-25 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 MKLM6_RS18005 8018d0ec0ba021b98b545e5de42554eb 129 Pfam PF02561 Flagellar protein FliS 21 128 2.7E-34 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 MKLM6_RS18005 8018d0ec0ba021b98b545e5de42554eb 129 Gene3D G3DSA:1.20.120.340 6 129 1.6E-37 T 28-03-2018 MKLM6_RS18005 8018d0ec0ba021b98b545e5de42554eb 129 SUPERFAMILY SSF101116 13 128 5.89E-34 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 MKLM6_RS18005 8018d0ec0ba021b98b545e5de42554eb 129 PIRSF PIRSF039090 5 129 1.0E-41 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 MKLM6_RS01155 dcc299590c9117f9795076842f0b78cc 342 Pfam PF00953 Glycosyl transferase family 4 72 230 3.0E-31 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 MKLM6_RS16890 2d64faef29db9f58b6b7cda7357b3fc2 129 ProSitePatterns PS00360 Ribosomal protein S9 signature. 68 86 - T 28-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 MKLM6_RS16890 2d64faef29db9f58b6b7cda7357b3fc2 129 Pfam PF00380 Ribosomal protein S9/S16 9 129 1.8E-43 T 28-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 MKLM6_RS16890 2d64faef29db9f58b6b7cda7357b3fc2 129 Gene3D G3DSA:3.30.230.10 2 129 3.9E-50 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MKLM6_RS16890 2d64faef29db9f58b6b7cda7357b3fc2 129 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 129 29.346 T 28-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid MKLM6_RS16890 2d64faef29db9f58b6b7cda7357b3fc2 129 SUPERFAMILY SSF54211 4 129 6.45E-45 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS06755 4399a98b096f027fbaf88b6ed3e27887 283 Pfam PF01774 UreD urease accessory protein 61 252 2.4E-43 T 28-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 MKLM6_RS06755 4399a98b096f027fbaf88b6ed3e27887 283 Hamap MF_01384 Urease accessory protein UreD [ureD]. 20 267 28.962 T 28-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 MKLM6_RS17245 35f46c3592da401d37b3b77e0e042d26 110 SUPERFAMILY SSF103481 6 105 8.89E-21 T 28-03-2018 MKLM6_RS17245 35f46c3592da401d37b3b77e0e042d26 110 Pfam PF00893 Small Multidrug Resistance protein 3 94 4.1E-29 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 MKLM6_RS19570 453513df1aff23fa7e0824dddbe25aaa 324 Gene3D G3DSA:3.90.226.10 57 284 2.3E-34 T 28-03-2018 MKLM6_RS19570 453513df1aff23fa7e0824dddbe25aaa 324 Pfam PF01343 Peptidase family S49 142 282 5.7E-38 T 28-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 MKLM6_RS19570 453513df1aff23fa7e0824dddbe25aaa 324 SUPERFAMILY SSF52096 72 186 1.16E-41 T 28-03-2018 IPR029045 ClpP/crotonase-like domain MKLM6_RS19570 453513df1aff23fa7e0824dddbe25aaa 324 SUPERFAMILY SSF52096 215 275 1.16E-41 T 28-03-2018 IPR029045 ClpP/crotonase-like domain MKLM6_RS19570 453513df1aff23fa7e0824dddbe25aaa 324 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 76 280 6.5E-50 T 28-03-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 MKLM6_RS17595 4ea3b66a57c464ea3b9ce5df81eddb8f 246 Gene3D G3DSA:3.40.50.150 7 243 2.4E-28 T 28-03-2018 MKLM6_RS17595 4ea3b66a57c464ea3b9ce5df81eddb8f 246 SUPERFAMILY SSF53335 30 228 1.37E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS17595 4ea3b66a57c464ea3b9ce5df81eddb8f 246 Pfam PF13649 Methyltransferase domain 53 153 9.7E-17 T 28-03-2018 MKLM6_RS04095 930a3f3b4ea39758766726c7a7609707 254 Pfam PF13646 HEAT repeats 139 221 3.4E-11 T 28-03-2018 MKLM6_RS04095 930a3f3b4ea39758766726c7a7609707 254 SUPERFAMILY SSF48371 145 250 8.86E-15 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 MKLM6_RS04095 930a3f3b4ea39758766726c7a7609707 254 Gene3D G3DSA:1.25.10.10 60 254 2.4E-15 T 28-03-2018 IPR011989 Armadillo-like helical MKLM6_RS10340 a8bd2cc83119a04a5978a59571cd2925 557 Gene3D G3DSA:3.40.50.300 11 237 8.4E-96 T 28-03-2018 MKLM6_RS10340 a8bd2cc83119a04a5978a59571cd2925 557 Gene3D G3DSA:3.40.50.300 238 444 2.1E-72 T 28-03-2018 MKLM6_RS10340 a8bd2cc83119a04a5978a59571cd2925 557 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 329 340 - T 28-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 MKLM6_RS10340 a8bd2cc83119a04a5978a59571cd2925 557 SUPERFAMILY SSF52540 3 555 2.83E-237 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS10340 a8bd2cc83119a04a5978a59571cd2925 557 Pfam PF01268 Formate--tetrahydrofolate ligase 1 557 5.5E-262 T 28-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 MKLM6_RS10340 a8bd2cc83119a04a5978a59571cd2925 557 Gene3D G3DSA:3.10.410.10 446 533 2.9E-31 T 28-03-2018 MKLM6_RS10340 a8bd2cc83119a04a5978a59571cd2925 557 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 103 113 - T 28-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 MKLM6_RS10340 a8bd2cc83119a04a5978a59571cd2925 557 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 1 557 47.906 T 28-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 MKLM6_RS10085 36e548489f9e2b9b07ed369dabcd4e4b 163 Pfam PF14341 PilX N-terminal 14 63 4.9E-12 T 28-03-2018 IPR025746 Type 4 fimbrial biogenesis protein PilX, N-terminal domain MKLM6_RS10085 36e548489f9e2b9b07ed369dabcd4e4b 163 Pfam PF13681 Type IV pilus assembly protein PilX C-term 93 157 1.3E-10 T 28-03-2018 IPR025205 PilX/PilW C-terminal domain MKLM6_RS00825 da9bba9a4d0c14c94524243841f762e3 365 SUPERFAMILY SSF51695 41 263 4.5E-50 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MKLM6_RS00825 da9bba9a4d0c14c94524243841f762e3 365 SUPERFAMILY SSF51695 324 364 4.5E-50 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MKLM6_RS00825 da9bba9a4d0c14c94524243841f762e3 365 Gene3D G3DSA:3.20.20.190 35 365 9.2E-42 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MKLM6_RS00825 da9bba9a4d0c14c94524243841f762e3 365 SMART SM00148 51 191 1.1E-8 T 28-03-2018 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain MKLM6_RS00825 da9bba9a4d0c14c94524243841f762e3 365 Pfam PF00388 Phosphatidylinositol-specific phospholipase C, X domain 77 188 6.6E-7 T 28-03-2018 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain MKLM6_RS10280 5ac4a1ed98664e8f3351f92808d12106 239 Gene3D G3DSA:3.20.20.70 65 232 5.6E-10 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS10280 5ac4a1ed98664e8f3351f92808d12106 239 Pfam PF04476 4-HFC-P synthase 4 219 7.4E-69 T 28-03-2018 IPR007565 (5-formylfuran-3-yl)methyl phosphate synthase KEGG: 00680+4.2.3.153|KEGG: 00902+4.2.3.15|MetaCyc: PWY-3041|MetaCyc: PWY-5254|MetaCyc: PWY-5423|MetaCyc: PWY-7410 MKLM6_RS10280 5ac4a1ed98664e8f3351f92808d12106 239 PIRSF PIRSF015957 2 229 1.9E-43 T 28-03-2018 IPR007565 (5-formylfuran-3-yl)methyl phosphate synthase KEGG: 00680+4.2.3.153|KEGG: 00902+4.2.3.15|MetaCyc: PWY-3041|MetaCyc: PWY-5254|MetaCyc: PWY-5423|MetaCyc: PWY-7410 MKLM6_RS10280 5ac4a1ed98664e8f3351f92808d12106 239 SUPERFAMILY SSF51366 14 148 5.18E-5 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MKLM6_RS07100 d4a158ca1123e4267542223e97d55926 403 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 12 400 2.4E-122 T 28-03-2018 IPR017687 Outer membrane protein assembly factor BamB MKLM6_RS07100 d4a158ca1123e4267542223e97d55926 403 Pfam PF13360 PQQ-like domain 97 329 1.0E-45 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat MKLM6_RS07100 d4a158ca1123e4267542223e97d55926 403 Pfam PF13360 PQQ-like domain 333 402 3.6E-4 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat MKLM6_RS07100 d4a158ca1123e4267542223e97d55926 403 SMART SM00564 339 371 2.9 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MKLM6_RS07100 d4a158ca1123e4267542223e97d55926 403 SMART SM00564 84 115 5.3E-4 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MKLM6_RS07100 d4a158ca1123e4267542223e97d55926 403 SMART SM00564 209 240 2.2 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MKLM6_RS07100 d4a158ca1123e4267542223e97d55926 403 SMART SM00564 124 155 2.6 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MKLM6_RS07100 d4a158ca1123e4267542223e97d55926 403 SMART SM00564 260 291 120.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MKLM6_RS07100 d4a158ca1123e4267542223e97d55926 403 SMART SM00564 299 330 110.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MKLM6_RS07100 d4a158ca1123e4267542223e97d55926 403 SMART SM00564 164 195 10.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MKLM6_RS07100 d4a158ca1123e4267542223e97d55926 403 Gene3D G3DSA:2.140.10.10 320 403 1.9E-12 T 28-03-2018 MKLM6_RS07100 d4a158ca1123e4267542223e97d55926 403 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 5 402 35.225 T 28-03-2018 IPR017687 Outer membrane protein assembly factor BamB MKLM6_RS07100 d4a158ca1123e4267542223e97d55926 403 Gene3D G3DSA:2.140.10.10 194 319 2.6E-14 T 28-03-2018 MKLM6_RS07100 d4a158ca1123e4267542223e97d55926 403 Gene3D G3DSA:2.140.10.10 42 193 2.4E-26 T 28-03-2018 MKLM6_RS07100 d4a158ca1123e4267542223e97d55926 403 SUPERFAMILY SSF50998 40 392 6.62E-69 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MKLM6_RS05605 15aa4776d07962a088a34bee5518cdb6 407 SUPERFAMILY SSF56935 224 407 2.78E-8 T 28-03-2018 MKLM6_RS05605 15aa4776d07962a088a34bee5518cdb6 407 SUPERFAMILY SSF56935 21 168 2.78E-8 T 28-03-2018 MKLM6_RS05605 15aa4776d07962a088a34bee5518cdb6 407 Gene3D G3DSA:2.40.160.10 14 407 5.2E-14 T 28-03-2018 MKLM6_RS02735 1eb038e1ac718f91088d3f7580182328 258 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 21 42 2.0E-26 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MKLM6_RS02735 1eb038e1ac718f91088d3f7580182328 258 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 80 99 2.0E-26 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MKLM6_RS02735 1eb038e1ac718f91088d3f7580182328 258 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 202 221 2.0E-26 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MKLM6_RS02735 1eb038e1ac718f91088d3f7580182328 258 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 180 202 2.0E-26 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MKLM6_RS02735 1eb038e1ac718f91088d3f7580182328 258 Pfam PF01311 Bacterial export proteins, family 1 13 245 2.2E-64 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MKLM6_RS02735 1eb038e1ac718f91088d3f7580182328 258 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 13 255 6.3E-69 T 28-03-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 MKLM6_RS05685 1f4b4c60ef554ad978e1d21a965d4c0b 181 Gene3D G3DSA:3.40.470.10 3 180 4.1E-21 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MKLM6_RS05685 1f4b4c60ef554ad978e1d21a965d4c0b 181 SMART SM00987 28 172 1.4E-4 T 28-03-2018 MKLM6_RS05685 1f4b4c60ef554ad978e1d21a965d4c0b 181 SUPERFAMILY SSF52141 21 178 3.27E-19 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MKLM6_RS05685 1f4b4c60ef554ad978e1d21a965d4c0b 181 SMART SM00986 28 172 1.4E-4 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MKLM6_RS05685 1f4b4c60ef554ad978e1d21a965d4c0b 181 Pfam PF03167 Uracil DNA glycosylase superfamily 28 167 6.7E-12 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MKLM6_RS11930 06405b770ae756c409de42b781e91e26 581 Gene3D G3DSA:3.30.1890.10 35 303 3.5E-15 T 28-03-2018 MKLM6_RS11930 06405b770ae756c409de42b781e91e26 581 Gene3D G3DSA:1.10.287.620 304 455 4.1E-8 T 28-03-2018 MKLM6_RS08985 4a315108f2565056c45ef3128937f156 455 Pfam PF05591 Type VI secretion system, VipA, VC_A0107 or Hcp2 26 106 3.0E-7 T 28-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 MKLM6_RS08985 4a315108f2565056c45ef3128937f156 455 Pfam PF05943 Type VI secretion protein, EvpB/VC_A0108, tail sheath 184 443 2.3E-25 T 28-03-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath MKLM6_RS20915 0b9d4d508b5eba657cb6ed98978a3d90 198 Pfam PF14103 Domain of unknown function (DUF4276) 8 187 9.0E-14 T 28-03-2018 IPR025455 Protein of unknown function DUF4276 MKLM6_RS00865 2840d6ebee9b5927f335549987c719ac 465 SUPERFAMILY SSF81342 14 283 2.04E-95 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MKLM6_RS00865 2840d6ebee9b5927f335549987c719ac 465 SUPERFAMILY SSF81648 284 400 6.98E-33 T 28-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 MKLM6_RS00865 2840d6ebee9b5927f335549987c719ac 465 PIRSF PIRSF038885 1 412 3.5E-162 T 28-03-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 MKLM6_RS00865 2840d6ebee9b5927f335549987c719ac 465 Gene3D G3DSA:1.20.810.10 11 404 1.3E-162 T 28-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 MKLM6_RS00865 2840d6ebee9b5927f335549987c719ac 465 Pfam PF00033 Cytochrome b/b6/petB 28 215 3.7E-67 T 28-03-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 MKLM6_RS00865 2840d6ebee9b5927f335549987c719ac 465 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 281 383 9.9E-45 T 28-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 MKLM6_RS13915 4bcd8daab41cf45af92c42667c34baa5 207 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 9 207 29.828 T 28-03-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 MKLM6_RS13915 4bcd8daab41cf45af92c42667c34baa5 207 Gene3D G3DSA:2.50.20.10 21 207 9.3E-46 T 28-03-2018 MKLM6_RS13915 4bcd8daab41cf45af92c42667c34baa5 207 SUPERFAMILY SSF89392 26 206 2.39E-49 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX MKLM6_RS13915 4bcd8daab41cf45af92c42667c34baa5 207 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 5 204 1.2E-26 T 28-03-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 MKLM6_RS13915 4bcd8daab41cf45af92c42667c34baa5 207 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 37 197 1.4E-49 T 28-03-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like MKLM6_RS02665 5616d464533de7f1d9722fa58ad30b2f 115 ProDom PD004816 MACROPHAGE MIGRATION INHIBITORY FACTOR TAUTOMERASE MIF PHENYLPYRUVATE CYTOKINE RESPONSE INFLAMMATORY 20 114 8.0E-20 T 28-03-2018 IPR001398 Macrophage migration inhibitory factor MKLM6_RS02665 5616d464533de7f1d9722fa58ad30b2f 115 Pfam PF01187 Macrophage migration inhibitory factor (MIF) 2 115 2.3E-23 T 28-03-2018 IPR001398 Macrophage migration inhibitory factor MKLM6_RS02665 5616d464533de7f1d9722fa58ad30b2f 115 Gene3D G3DSA:3.30.429.10 2 115 1.3E-31 T 28-03-2018 MKLM6_RS02665 5616d464533de7f1d9722fa58ad30b2f 115 SUPERFAMILY SSF55331 1 115 1.22E-30 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily MKLM6_RS13080 840b797ca8fa6d6a616d714752b164e2 183 Gene3D G3DSA:2.40.440.10 23 183 1.3E-28 T 28-03-2018 MKLM6_RS13080 840b797ca8fa6d6a616d714752b164e2 183 SUPERFAMILY SSF141523 109 182 2.62E-27 T 28-03-2018 MKLM6_RS13080 840b797ca8fa6d6a616d714752b164e2 183 SUPERFAMILY SSF141523 26 81 2.62E-27 T 28-03-2018 MKLM6_RS13080 840b797ca8fa6d6a616d714752b164e2 183 Pfam PF03734 L,D-transpeptidase catalytic domain 28 181 1.8E-21 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MKLM6_RS11155 d32a4c53bd9f8eb87032b9e5edaf45d4 301 SMART SM00382 29 211 1.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS11155 d32a4c53bd9f8eb87032b9e5edaf45d4 301 Gene3D G3DSA:3.40.50.300 1 286 3.2E-63 T 28-03-2018 MKLM6_RS11155 d32a4c53bd9f8eb87032b9e5edaf45d4 301 SUPERFAMILY SSF52540 3 229 1.31E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS11155 d32a4c53bd9f8eb87032b9e5edaf45d4 301 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS11155 d32a4c53bd9f8eb87032b9e5edaf45d4 301 Pfam PF00005 ABC transporter 20 164 2.8E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS20640 2dc94182a65667bb46692eb60d731af6 231 Gene3D G3DSA:3.30.1330.60 70 223 6.4E-18 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS20640 2dc94182a65667bb46692eb60d731af6 231 PRINTS PR01021 OMPA domain signature 153 168 3.0E-5 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MKLM6_RS20640 2dc94182a65667bb46692eb60d731af6 231 PRINTS PR01021 OMPA domain signature 168 184 3.0E-5 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MKLM6_RS20640 2dc94182a65667bb46692eb60d731af6 231 Pfam PF00691 OmpA family 122 208 1.5E-12 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS20640 2dc94182a65667bb46692eb60d731af6 231 SUPERFAMILY SSF103088 109 202 2.75E-16 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS15935 4df38fb04d77e2e9e2d9f0042c9359e9 450 Pfam PF00990 Diguanylate cyclase, GGDEF domain 286 439 3.6E-43 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS15935 4df38fb04d77e2e9e2d9f0042c9359e9 450 SMART SM00116 206 254 4.0E-5 T 28-03-2018 IPR000644 CBS domain MKLM6_RS15935 4df38fb04d77e2e9e2d9f0042c9359e9 450 SMART SM00116 16 62 21.0 T 28-03-2018 IPR000644 CBS domain MKLM6_RS15935 4df38fb04d77e2e9e2d9f0042c9359e9 450 SMART SM00116 78 126 8.9E-5 T 28-03-2018 IPR000644 CBS domain MKLM6_RS15935 4df38fb04d77e2e9e2d9f0042c9359e9 450 SMART SM00116 144 190 0.091 T 28-03-2018 IPR000644 CBS domain MKLM6_RS15935 4df38fb04d77e2e9e2d9f0042c9359e9 450 SUPERFAMILY SSF55073 291 442 3.06E-44 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS15935 4df38fb04d77e2e9e2d9f0042c9359e9 450 Gene3D G3DSA:3.10.580.10 130 268 4.4E-24 T 28-03-2018 MKLM6_RS15935 4df38fb04d77e2e9e2d9f0042c9359e9 450 Gene3D G3DSA:3.10.580.10 2 129 1.8E-12 T 28-03-2018 MKLM6_RS15935 4df38fb04d77e2e9e2d9f0042c9359e9 450 SUPERFAMILY SSF54631 8 125 2.02E-15 T 28-03-2018 MKLM6_RS15935 4df38fb04d77e2e9e2d9f0042c9359e9 450 SMART SM00267 275 444 9.1E-51 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS15935 4df38fb04d77e2e9e2d9f0042c9359e9 450 Pfam PF00571 CBS domain 200 252 2.0E-7 T 28-03-2018 IPR000644 CBS domain MKLM6_RS15935 4df38fb04d77e2e9e2d9f0042c9359e9 450 Pfam PF00571 CBS domain 137 190 1.6E-8 T 28-03-2018 IPR000644 CBS domain MKLM6_RS15935 4df38fb04d77e2e9e2d9f0042c9359e9 450 Pfam PF00571 CBS domain 72 125 1.4E-5 T 28-03-2018 IPR000644 CBS domain MKLM6_RS15935 4df38fb04d77e2e9e2d9f0042c9359e9 450 SUPERFAMILY SSF54631 134 262 3.79E-24 T 28-03-2018 MKLM6_RS15935 4df38fb04d77e2e9e2d9f0042c9359e9 450 Gene3D G3DSA:3.30.70.270 276 445 3.4E-52 T 28-03-2018 MKLM6_RS15935 4df38fb04d77e2e9e2d9f0042c9359e9 450 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 282 443 4.3E-46 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS22100 c55a45f06d74f02d8842a07082321bf0 82 Gene3D G3DSA:2.10.260.10 1 80 2.6E-21 T 28-03-2018 MKLM6_RS22100 c55a45f06d74f02d8842a07082321bf0 82 SUPERFAMILY SSF89447 1 74 6.98E-19 T 28-03-2018 MKLM6_RS22100 c55a45f06d74f02d8842a07082321bf0 82 SMART SM00966 6 51 1.3E-8 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MKLM6_RS22100 c55a45f06d74f02d8842a07082321bf0 82 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 6 48 1.4E-8 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MKLM6_RS06605 ba6f13cb37a8ff63f8ba17e51372053d 98 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 20 77 1.1E-8 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MKLM6_RS06605 ba6f13cb37a8ff63f8ba17e51372053d 98 SUPERFAMILY SSF143120 20 67 9.16E-10 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MKLM6_RS06605 ba6f13cb37a8ff63f8ba17e51372053d 98 Gene3D G3DSA:3.40.1620.10 20 71 5.1E-10 T 28-03-2018 MKLM6_RS16130 55013664248cf580594bcf2f2c92e7e4 322 Pfam PF01145 SPFH domain / Band 7 family 24 229 3.1E-27 T 28-03-2018 IPR001107 Band 7 domain MKLM6_RS16130 55013664248cf580594bcf2f2c92e7e4 322 SUPERFAMILY SSF117892 53 137 6.54E-21 T 28-03-2018 IPR001107 Band 7 domain MKLM6_RS16130 55013664248cf580594bcf2f2c92e7e4 322 SUPERFAMILY SSF117892 169 217 6.54E-21 T 28-03-2018 IPR001107 Band 7 domain MKLM6_RS16130 55013664248cf580594bcf2f2c92e7e4 322 SMART SM00244 20 213 5.3E-22 T 28-03-2018 IPR001107 Band 7 domain MKLM6_RS16130 55013664248cf580594bcf2f2c92e7e4 322 TIGRFAM TIGR01932 hflC: HflC protein 10 314 2.5E-72 T 28-03-2018 IPR010200 HflC GO:0016021|GO:0052547 MKLM6_RS16130 55013664248cf580594bcf2f2c92e7e4 322 PIRSF PIRSF005651 5 322 3.5E-93 T 28-03-2018 IPR010200 HflC GO:0016021|GO:0052547 MKLM6_RS15045 93c087a7d2da920cba4e898d511d2b0b 124 SUPERFAMILY SSF54593 6 123 5.37E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MKLM6_RS15045 93c087a7d2da920cba4e898d511d2b0b 124 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 120 1.9E-12 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MKLM6_RS15045 93c087a7d2da920cba4e898d511d2b0b 124 Gene3D G3DSA:3.10.180.10 1 124 1.8E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MKLM6_RS03020 e823362bbd0b6c080f677dcbbfdbe366 603 SUPERFAMILY SSF88659 441 514 2.62E-21 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS03020 e823362bbd0b6c080f677dcbbfdbe366 603 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 364 589 7.3E-36 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS03020 e823362bbd0b6c080f677dcbbfdbe366 603 Pfam PF04542 Sigma-70 region 2 368 437 1.7E-21 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS03020 e823362bbd0b6c080f677dcbbfdbe366 603 Pfam PF04545 Sigma-70, region 4 536 589 9.9E-19 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS03020 e823362bbd0b6c080f677dcbbfdbe366 603 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 561 587 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS03020 e823362bbd0b6c080f677dcbbfdbe366 603 Pfam PF04546 Sigma-70, non-essential region 145 337 1.4E-40 T 28-03-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS03020 e823362bbd0b6c080f677dcbbfdbe366 603 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 5 601 41.814 T 28-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 MKLM6_RS03020 e823362bbd0b6c080f677dcbbfdbe366 603 Pfam PF03979 Sigma-70 factor, region 1.1 4 84 4.0E-30 T 28-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 MKLM6_RS03020 e823362bbd0b6c080f677dcbbfdbe366 603 PRINTS PR00046 Major sigma-70 factor signature 540 552 5.9E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS03020 e823362bbd0b6c080f677dcbbfdbe366 603 PRINTS PR00046 Major sigma-70 factor signature 392 405 5.9E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS03020 e823362bbd0b6c080f677dcbbfdbe366 603 PRINTS PR00046 Major sigma-70 factor signature 576 587 5.9E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS03020 e823362bbd0b6c080f677dcbbfdbe366 603 PRINTS PR00046 Major sigma-70 factor signature 416 424 5.9E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS03020 e823362bbd0b6c080f677dcbbfdbe366 603 PRINTS PR00046 Major sigma-70 factor signature 561 576 5.9E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS03020 e823362bbd0b6c080f677dcbbfdbe366 603 Gene3D G3DSA:1.10.10.10 530 601 2.5E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS03020 e823362bbd0b6c080f677dcbbfdbe366 603 Pfam PF04539 Sigma-70 region 3 447 522 4.9E-30 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS03020 e823362bbd0b6c080f677dcbbfdbe366 603 SUPERFAMILY SSF88946 117 435 3.45E-87 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS03020 e823362bbd0b6c080f677dcbbfdbe366 603 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 364 600 5.2E-120 T 28-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS03020 e823362bbd0b6c080f677dcbbfdbe366 603 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 392 405 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS03020 e823362bbd0b6c080f677dcbbfdbe366 603 SUPERFAMILY SSF88659 498 600 1.02E-25 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS03020 e823362bbd0b6c080f677dcbbfdbe366 603 Gene3D G3DSA:1.10.10.10 438 488 2.6E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS03020 e823362bbd0b6c080f677dcbbfdbe366 603 Pfam PF00140 Sigma-70 factor, region 1.2 100 131 2.9E-13 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS03020 e823362bbd0b6c080f677dcbbfdbe366 603 Gene3D G3DSA:1.10.601.10 2 124 2.2E-20 T 28-03-2018 MKLM6_RS03020 e823362bbd0b6c080f677dcbbfdbe366 603 Gene3D G3DSA:1.10.601.10 125 437 2.0E-87 T 28-03-2018 MKLM6_RS03530 50801396c56247574939f9931a5628b9 129 Pfam PF06155 Protein of unknown function (DUF971) 15 99 5.0E-28 T 28-03-2018 IPR010376 Domain of unknown function DUF971 Reactome: R-HSA-71262 MKLM6_RS04065 7ab77fc484a14ce41fb99fc230308a3f 318 Gene3D G3DSA:3.90.1580.10 43 318 3.6E-78 T 28-03-2018 MKLM6_RS04065 7ab77fc484a14ce41fb99fc230308a3f 318 SUPERFAMILY SSF56436 57 317 3.06E-73 T 28-03-2018 IPR016187 C-type lectin fold MKLM6_RS04065 7ab77fc484a14ce41fb99fc230308a3f 318 Pfam PF03781 Sulfatase-modifying factor enzyme 1 58 316 1.7E-67 T 28-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 MKLM6_RS00110 c3e59d8dd346ff7f4d685d43024cca86 178 Pfam PF06041 Bacterial protein of unknown function (DUF924) 5 175 1.4E-62 T 28-03-2018 IPR010323 Protein of unknown function DUF924 MKLM6_RS00110 c3e59d8dd346ff7f4d685d43024cca86 178 Gene3D G3DSA:1.25.40.10 78 178 1.3E-35 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS00110 c3e59d8dd346ff7f4d685d43024cca86 178 SUPERFAMILY SSF48452 2 174 1.1E-66 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS00110 c3e59d8dd346ff7f4d685d43024cca86 178 Gene3D G3DSA:1.20.58.320 1 77 1.0E-23 T 28-03-2018 MKLM6_RS16740 16b4d8e26abb8b669facde3b9ddb05b5 269 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 25 87 4.3E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS16740 16b4d8e26abb8b669facde3b9ddb05b5 269 SUPERFAMILY SSF46785 21 125 1.77E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS16740 16b4d8e26abb8b669facde3b9ddb05b5 269 Gene3D G3DSA:1.10.10.10 10 111 1.0E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS16740 16b4d8e26abb8b669facde3b9ddb05b5 269 SUPERFAMILY SSF50331 131 264 6.56E-19 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal MKLM6_RS16740 16b4d8e26abb8b669facde3b9ddb05b5 269 PIRSF PIRSF005763 12 268 1.2E-64 T 28-03-2018 IPR016462 Molybdate-dependent transcriptional regulator ModE GO:0006355|GO:0015689|GO:0030151 MKLM6_RS16740 16b4d8e26abb8b669facde3b9ddb05b5 269 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 198 265 1.9E-17 T 28-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 MKLM6_RS16740 16b4d8e26abb8b669facde3b9ddb05b5 269 Gene3D G3DSA:2.40.50.100 198 266 1.5E-15 T 28-03-2018 MKLM6_RS16740 16b4d8e26abb8b669facde3b9ddb05b5 269 Gene3D G3DSA:2.40.50.100 112 185 7.3E-9 T 28-03-2018 MKLM6_RS16740 16b4d8e26abb8b669facde3b9ddb05b5 269 Pfam PF03459 TOBE domain 201 263 4.8E-12 T 28-03-2018 IPR005116 Transport-associated OB, type 1 MKLM6_RS16740 16b4d8e26abb8b669facde3b9ddb05b5 269 Pfam PF03459 TOBE domain 128 189 1.5E-6 T 28-03-2018 IPR005116 Transport-associated OB, type 1 MKLM6_RS20950 2245144d820320b6ab36d2df3409a56a 329 SUPERFAMILY SSF51735 5 155 2.09E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS20950 2245144d820320b6ab36d2df3409a56a 329 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 138 236 1.2E-7 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 MKLM6_RS20950 2245144d820320b6ab36d2df3409a56a 329 Gene3D G3DSA:3.30.360.10 138 326 7.3E-35 T 28-03-2018 MKLM6_RS20950 2245144d820320b6ab36d2df3409a56a 329 SUPERFAMILY SSF55347 132 289 8.01E-33 T 28-03-2018 MKLM6_RS20950 2245144d820320b6ab36d2df3409a56a 329 Gene3D G3DSA:3.40.50.720 2 137 7.7E-39 T 28-03-2018 MKLM6_RS20950 2245144d820320b6ab36d2df3409a56a 329 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 126 1.5E-24 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MKLM6_RS19225 0f9f428818e78c8a812bb25ed48f65ce 887 Gene3D G3DSA:3.30.70.100 1 98 9.2E-18 T 28-03-2018 MKLM6_RS19225 0f9f428818e78c8a812bb25ed48f65ce 887 Gene3D G3DSA:3.30.420.40 688 859 1.3E-28 T 28-03-2018 MKLM6_RS19225 0f9f428818e78c8a812bb25ed48f65ce 887 Pfam PF01300 Telomere recombination 278 452 1.9E-51 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 MKLM6_RS19225 0f9f428818e78c8a812bb25ed48f65ce 887 Gene3D G3DSA:3.90.870.10 257 460 8.4E-56 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain MKLM6_RS19225 0f9f428818e78c8a812bb25ed48f65ce 887 Pfam PF07503 HypF finger 158 190 6.6E-17 T 28-03-2018 IPR011125 Zinc finger, HypF-type GO:0008270 MKLM6_RS19225 0f9f428818e78c8a812bb25ed48f65ce 887 Pfam PF07503 HypF finger 108 141 1.3E-16 T 28-03-2018 IPR011125 Zinc finger, HypF-type GO:0008270 MKLM6_RS19225 0f9f428818e78c8a812bb25ed48f65ce 887 SUPERFAMILY SSF54975 4 91 5.67E-20 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MKLM6_RS19225 0f9f428818e78c8a812bb25ed48f65ce 887 Pfam PF00708 Acylphosphatase 6 89 2.7E-15 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MKLM6_RS19225 0f9f428818e78c8a812bb25ed48f65ce 887 SUPERFAMILY SSF55821 273 458 1.4E-46 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain MKLM6_RS11195 9278040107dc83db4a75e1c6d0de241b 418 Pfam PF01882 Protein of unknown function DUF58 201 281 1.2E-22 T 28-03-2018 IPR002881 Domain of unknown function DUF58 MKLM6_RS11195 9278040107dc83db4a75e1c6d0de241b 418 Gene3D G3DSA:3.40.50.410 211 388 2.1E-8 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS03110 3e0751b7bd2a9aed58d012354af41884 261 Pfam PF01435 Peptidase family M48 73 238 3.4E-36 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MKLM6_RS03110 3e0751b7bd2a9aed58d012354af41884 261 Gene3D G3DSA:3.30.2010.10 45 138 4.2E-21 T 28-03-2018 MKLM6_RS22235 9e736d780dd4eb3aa11a55f7c987501a 1035 Gene3D G3DSA:3.40.50.150 29 230 3.5E-8 T 28-03-2018 MKLM6_RS22235 9e736d780dd4eb3aa11a55f7c987501a 1035 SUPERFAMILY SSF52540 839 994 2.29E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS22235 9e736d780dd4eb3aa11a55f7c987501a 1035 SUPERFAMILY SSF52540 618 659 2.29E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS22235 9e736d780dd4eb3aa11a55f7c987501a 1035 Gene3D G3DSA:3.40.50.300 842 999 3.0E-15 T 28-03-2018 MKLM6_RS22235 9e736d780dd4eb3aa11a55f7c987501a 1035 Gene3D G3DSA:3.40.50.10810 511 825 1.0E-12 T 28-03-2018 MKLM6_RS22235 9e736d780dd4eb3aa11a55f7c987501a 1035 SUPERFAMILY SSF52540 506 672 3.85E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS22235 9e736d780dd4eb3aa11a55f7c987501a 1035 SUPERFAMILY SSF53335 31 233 1.06E-13 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS14530 6d90af8e3e416d826c2d8c7dc2e3f63a 146 SUPERFAMILY SSF160574 17 142 4.05E-8 T 28-03-2018 MKLM6_RS02825 4d2506d4696d88e2f4223315cf0a4829 274 Gene3D G3DSA:3.90.550.10 7 214 4.1E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS02825 4d2506d4696d88e2f4223315cf0a4829 274 SUPERFAMILY SSF53448 8 204 1.23E-29 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS02825 4d2506d4696d88e2f4223315cf0a4829 274 SUPERFAMILY SSF53448 232 242 1.23E-29 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS02825 4d2506d4696d88e2f4223315cf0a4829 274 Pfam PF00535 Glycosyl transferase family 2 11 127 7.4E-17 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MKLM6_RS11220 2b1c70d1116fd0b88ae7c4d82a353094 109 Gene3D G3DSA:3.30.420.10 1 95 5.8E-7 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS11220 2b1c70d1116fd0b88ae7c4d82a353094 109 Pfam PF13358 DDE superfamily endonuclease 2 95 6.5E-25 T 28-03-2018 MKLM6_RS15830 9f1b4953c712db724a76f21976c02cdf 264 Gene3D G3DSA:3.40.50.150 6 263 2.4E-25 T 28-03-2018 MKLM6_RS15830 9f1b4953c712db724a76f21976c02cdf 264 SUPERFAMILY SSF53335 38 217 2.94E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS15830 9f1b4953c712db724a76f21976c02cdf 264 Pfam PF13847 Methyltransferase domain 47 163 1.9E-13 T 28-03-2018 IPR025714 Methyltransferase domain MKLM6_RS19205 8ee2fde21f56233044f495f0191c517f 365 SUPERFAMILY SSF50621 236 363 5.23E-47 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MKLM6_RS19205 8ee2fde21f56233044f495f0191c517f 365 PRINTS PR00992 Alanine racemase signature 122 134 6.7E-60 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MKLM6_RS19205 8ee2fde21f56233044f495f0191c517f 365 PRINTS PR00992 Alanine racemase signature 259 274 6.7E-60 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MKLM6_RS19205 8ee2fde21f56233044f495f0191c517f 365 PRINTS PR00992 Alanine racemase signature 202 229 6.7E-60 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MKLM6_RS19205 8ee2fde21f56233044f495f0191c517f 365 PRINTS PR00992 Alanine racemase signature 276 291 6.7E-60 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MKLM6_RS19205 8ee2fde21f56233044f495f0191c517f 365 PRINTS PR00992 Alanine racemase signature 297 314 6.7E-60 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MKLM6_RS19205 8ee2fde21f56233044f495f0191c517f 365 PRINTS PR00992 Alanine racemase signature 61 79 6.7E-60 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MKLM6_RS19205 8ee2fde21f56233044f495f0191c517f 365 PRINTS PR00992 Alanine racemase signature 27 43 6.7E-60 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MKLM6_RS19205 8ee2fde21f56233044f495f0191c517f 365 PRINTS PR00992 Alanine racemase signature 157 168 6.7E-60 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MKLM6_RS19205 8ee2fde21f56233044f495f0191c517f 365 PRINTS PR00992 Alanine racemase signature 349 362 6.7E-60 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MKLM6_RS19205 8ee2fde21f56233044f495f0191c517f 365 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 32 42 - T 28-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MKLM6_RS19205 8ee2fde21f56233044f495f0191c517f 365 TIGRFAM TIGR00492 alr: alanine racemase 5 364 1.9E-114 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MKLM6_RS19205 8ee2fde21f56233044f495f0191c517f 365 Pfam PF00842 Alanine racemase, C-terminal domain 243 363 1.5E-42 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MKLM6_RS19205 8ee2fde21f56233044f495f0191c517f 365 Hamap MF_01201 Alanine racemase. 2 364 33.376 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MKLM6_RS19205 8ee2fde21f56233044f495f0191c517f 365 SMART SM01005 243 365 1.1E-63 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MKLM6_RS19205 8ee2fde21f56233044f495f0191c517f 365 Pfam PF01168 Alanine racemase, N-terminal domain 9 229 3.2E-63 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MKLM6_RS19205 8ee2fde21f56233044f495f0191c517f 365 Gene3D G3DSA:3.20.20.10 3 221 1.2E-40 T 28-03-2018 IPR029066 PLP-binding barrel MKLM6_RS19205 8ee2fde21f56233044f495f0191c517f 365 SUPERFAMILY SSF51419 9 244 3.78E-62 T 28-03-2018 IPR029066 PLP-binding barrel MKLM6_RS19205 8ee2fde21f56233044f495f0191c517f 365 Gene3D G3DSA:2.40.37.10 222 365 2.1E-56 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MKLM6_RS04700 f217b51fbeeb02b777fd4a095b63f95e 493 Pfam PF05872 Bacterial protein of unknown function (DUF853) 5 493 9.8E-227 T 28-03-2018 IPR033186 Helicase HerA-like C-terminal MKLM6_RS04700 f217b51fbeeb02b777fd4a095b63f95e 493 Gene3D G3DSA:3.40.50.300 9 347 6.2E-27 T 28-03-2018 MKLM6_RS04700 f217b51fbeeb02b777fd4a095b63f95e 493 SUPERFAMILY SSF52540 18 382 4.91E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS12140 e94a2581f7fd4b50d89ad4f45459aa42 323 Pfam PF08279 HTH domain 6 61 6.2E-5 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 MKLM6_RS12140 e94a2581f7fd4b50d89ad4f45459aa42 323 Gene3D G3DSA:1.10.10.10 1 65 1.9E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS12140 e94a2581f7fd4b50d89ad4f45459aa42 323 Pfam PF13280 WYL domain 146 319 5.6E-41 T 28-03-2018 IPR026881 WYL domain MKLM6_RS10195 6b99909d226651d572982b018b9cdb58 208 Pfam PF01300 Telomere recombination 23 198 1.5E-44 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 MKLM6_RS10195 6b99909d226651d572982b018b9cdb58 208 Gene3D G3DSA:3.90.870.10 1 206 1.0E-56 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain MKLM6_RS10195 6b99909d226651d572982b018b9cdb58 208 SUPERFAMILY SSF55821 1 205 7.32E-61 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain MKLM6_RS10195 6b99909d226651d572982b018b9cdb58 208 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 201 6.6E-61 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 Pfam PF01131 DNA topoisomerase 133 562 2.6E-128 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 SUPERFAMILY SSF56712 3 604 4.32E-192 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 302 311 5.4E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 380 396 5.4E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 166 184 5.4E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 5.4E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 488 502 5.4E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 701 53.886 T 28-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 625 1.1E-242 T 28-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 Gene3D G3DSA:2.70.20.10 335 462 6.7E-40 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 643 679 3.8E-15 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 591 626 4.9E-15 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 685 722 1.0E-11 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 Pfam PF01751 Toprim domain 5 117 5.8E-26 T 28-03-2018 IPR006171 TOPRIM domain MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 SUPERFAMILY SSF57783 636 678 1.28E-12 T 28-03-2018 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 SMART SM00493 3 103 9.1E-32 T 28-03-2018 IPR006171 TOPRIM domain MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 SUPERFAMILY SSF57783 590 628 6.29E-11 T 28-03-2018 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 289 311 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 SMART SM00436 108 196 8.5E-48 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 SMART SM00437 252 525 1.1E-120 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 Gene3D G3DSA:3.40.50.140 2 133 9.4E-40 T 28-03-2018 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 Gene3D G3DSA:1.10.460.10 463 579 2.4E-26 T 28-03-2018 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 Gene3D G3DSA:1.10.460.10 139 334 7.4E-47 T 28-03-2018 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 Gene3D G3DSA:3.30.65.10 633 679 7.7E-17 T 28-03-2018 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 Gene3D G3DSA:3.30.65.10 680 723 2.3E-11 T 28-03-2018 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 Gene3D G3DSA:3.30.65.10 724 769 0.063 T 28-03-2018 MKLM6_RS16835 63de43e798d77b2f39c7a3f50fa1e986 771 Gene3D G3DSA:3.30.65.10 580 632 3.5E-17 T 28-03-2018 MKLM6_RS16365 57145d92c54ef45b5f275191e855509d 63 Hamap MF_00167 Carbon storage regulator [csrA]. 1 62 21.251 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 MKLM6_RS16365 57145d92c54ef45b5f275191e855509d 63 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 49 5.0E-21 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 MKLM6_RS16365 57145d92c54ef45b5f275191e855509d 63 Pfam PF02599 Global regulator protein family 1 52 3.3E-27 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 MKLM6_RS16365 57145d92c54ef45b5f275191e855509d 63 SUPERFAMILY SSF117130 1 54 2.62E-21 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 MKLM6_RS16365 57145d92c54ef45b5f275191e855509d 63 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 58 1.0E-30 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 MKLM6_RS03140 3229e27498045112fff3fe8e5b450d71 437 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 39 297 1.9E-31 T 28-03-2018 IPR017039 Virulence factor BrkB MKLM6_RS03140 3229e27498045112fff3fe8e5b450d71 437 Pfam PF03631 Virulence factor BrkB 44 297 1.1E-49 T 28-03-2018 IPR017039 Virulence factor BrkB MKLM6_RS18385 4dd693df0d3e8405e193f956a484f16d 105 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 103 2.3E-36 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18385 4dd693df0d3e8405e193f956a484f16d 105 Gene3D G3DSA:2.30.30.30 2 92 2.4E-27 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 MKLM6_RS18385 4dd693df0d3e8405e193f956a484f16d 105 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 2 97 19.181 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18385 4dd693df0d3e8405e193f956a484f16d 105 SUPERFAMILY SSF50104 3 100 3.81E-30 T 28-03-2018 IPR008991 Translation protein SH3-like domain MKLM6_RS18385 4dd693df0d3e8405e193f956a484f16d 105 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 103 1.3E-23 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18385 4dd693df0d3e8405e193f956a484f16d 105 Pfam PF00467 KOW motif 7 36 2.0E-5 T 28-03-2018 IPR005824 KOW MKLM6_RS18385 4dd693df0d3e8405e193f956a484f16d 105 SMART SM00739 3 30 0.0025 T 28-03-2018 IPR005824 KOW MKLM6_RS21475 79e6dd5e13205938b5a93acee8147c9e 319 Gene3D G3DSA:2.40.440.10 91 233 8.3E-32 T 28-03-2018 MKLM6_RS21475 79e6dd5e13205938b5a93acee8147c9e 319 Gene3D G3DSA:3.10.350.10 39 87 0.002 T 28-03-2018 MKLM6_RS21475 79e6dd5e13205938b5a93acee8147c9e 319 Pfam PF03734 L,D-transpeptidase catalytic domain 98 231 2.1E-22 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MKLM6_RS21475 79e6dd5e13205938b5a93acee8147c9e 319 SUPERFAMILY SSF141523 96 231 4.58E-32 T 28-03-2018 MKLM6_RS10110 68f6029c0f4d3e4cddff3d12d1d144f5 693 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 473 7.6E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS10110 68f6029c0f4d3e4cddff3d12d1d144f5 693 PRINTS PR00344 Bacterial sensor protein C-terminal signature 539 552 7.6E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS10110 68f6029c0f4d3e4cddff3d12d1d144f5 693 PRINTS PR00344 Bacterial sensor protein C-terminal signature 515 533 7.6E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS10110 68f6029c0f4d3e4cddff3d12d1d144f5 693 PRINTS PR00344 Bacterial sensor protein C-terminal signature 499 509 7.6E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS10110 68f6029c0f4d3e4cddff3d12d1d144f5 693 Gene3D G3DSA:2.30.30.40 633 688 9.4E-22 T 28-03-2018 MKLM6_RS10110 68f6029c0f4d3e4cddff3d12d1d144f5 693 Pfam PF01584 CheW-like domain 564 689 1.3E-23 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS10110 68f6029c0f4d3e4cddff3d12d1d144f5 693 Gene3D G3DSA:2.40.50.180 578 632 4.2E-9 T 28-03-2018 MKLM6_RS10110 68f6029c0f4d3e4cddff3d12d1d144f5 693 Gene3D G3DSA:1.20.120.160 1 154 3.1E-32 T 28-03-2018 MKLM6_RS10110 68f6029c0f4d3e4cddff3d12d1d144f5 693 SUPERFAMILY SSF47226 4 120 3.3E-31 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS10110 68f6029c0f4d3e4cddff3d12d1d144f5 693 Pfam PF01627 Hpt domain 9 107 3.1E-20 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS10110 68f6029c0f4d3e4cddff3d12d1d144f5 693 Gene3D G3DSA:1.10.287.560 306 370 8.2E-21 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 MKLM6_RS10110 68f6029c0f4d3e4cddff3d12d1d144f5 693 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 306 369 1.4E-18 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 MKLM6_RS10110 68f6029c0f4d3e4cddff3d12d1d144f5 693 SUPERFAMILY SSF55874 372 553 7.86E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS10110 68f6029c0f4d3e4cddff3d12d1d144f5 693 SMART SM00073 5 102 1.7E-31 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MKLM6_RS10110 68f6029c0f4d3e4cddff3d12d1d144f5 693 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 416 554 3.3E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS10110 68f6029c0f4d3e4cddff3d12d1d144f5 693 SMART SM00260 547 688 9.8E-39 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS10110 68f6029c0f4d3e4cddff3d12d1d144f5 693 SMART SM01231 306 369 3.0E-21 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 MKLM6_RS10110 68f6029c0f4d3e4cddff3d12d1d144f5 693 SUPERFAMILY SSF47384 307 370 1.65E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS10110 68f6029c0f4d3e4cddff3d12d1d144f5 693 Gene3D G3DSA:3.30.565.10 372 561 4.7E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS10110 68f6029c0f4d3e4cddff3d12d1d144f5 693 SUPERFAMILY SSF50341 554 688 5.49E-30 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MKLM6_RS10110 68f6029c0f4d3e4cddff3d12d1d144f5 693 SMART SM00387 414 555 1.2E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13460 4fb232825fcbf1348dc18a7c9e500e5a 456 Pfam PF10129 OpgC protein 11 364 4.3E-95 T 28-03-2018 IPR014550 Uncharacterised conserved protein UCP028704, OpgC MKLM6_RS13460 4fb232825fcbf1348dc18a7c9e500e5a 456 PIRSF PIRSF028704 2 384 1.2E-85 T 28-03-2018 IPR014550 Uncharacterised conserved protein UCP028704, OpgC MKLM6_RS06800 8e84bbd1f947c47afc6e5fb3a73704df 417 Gene3D G3DSA:2.40.160.10 30 416 7.6E-31 T 28-03-2018 MKLM6_RS22025 bb29fc4576e9d12154b44f1186ec6448 589 SUPERFAMILY SSF53335 28 176 7.93E-6 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS22025 bb29fc4576e9d12154b44f1186ec6448 589 Pfam PF13708 Domain of unknown function (DUF4942) 280 475 2.2E-47 T 28-03-2018 IPR031339 Domain of unknown function DUF4942 MKLM6_RS10145 a7c1c32c46f1b3eef18587cb52beec88 212 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 25 184 27.514 T 28-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 MKLM6_RS10145 a7c1c32c46f1b3eef18587cb52beec88 212 Pfam PF03975 CheD chemotactic sensory transduction 73 180 1.0E-28 T 28-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 MKLM6_RS10145 a7c1c32c46f1b3eef18587cb52beec88 212 SUPERFAMILY SSF64438 32 186 1.37E-46 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic MKLM6_RS06355 69c778b479ce1a26692731f7cdee041f 461 Pfam PF00202 Aminotransferase class-III 40 435 1.2E-99 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MKLM6_RS06355 69c778b479ce1a26692731f7cdee041f 461 PIRSF PIRSF000521 183 438 8.5E-30 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MKLM6_RS06355 69c778b479ce1a26692731f7cdee041f 461 PIRSF PIRSF000521 18 143 3.1E-15 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MKLM6_RS06355 69c778b479ce1a26692731f7cdee041f 461 PIRSF PIRSF000521 136 168 2.8 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MKLM6_RS06355 69c778b479ce1a26692731f7cdee041f 461 Gene3D G3DSA:3.40.640.10 184 323 2.4E-44 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS06355 69c778b479ce1a26692731f7cdee041f 461 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 233 270 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MKLM6_RS06355 69c778b479ce1a26692731f7cdee041f 461 Gene3D G3DSA:3.90.1150.10 5 183 7.6E-36 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS06355 69c778b479ce1a26692731f7cdee041f 461 SUPERFAMILY SSF53383 32 436 5.5E-116 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS02090 aa29b46c3795e713f94fb71a4fe0b972 297 SUPERFAMILY SSF74653 96 109 6.04E-17 T 28-03-2018 MKLM6_RS02090 aa29b46c3795e713f94fb71a4fe0b972 297 SUPERFAMILY SSF74653 184 290 6.04E-17 T 28-03-2018 MKLM6_RS02090 aa29b46c3795e713f94fb71a4fe0b972 297 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 210 281 2.1E-12 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 MKLM6_RS02090 aa29b46c3795e713f94fb71a4fe0b972 297 Gene3D G3DSA:3.30.1150.10 117 296 2.2E-20 T 28-03-2018 MKLM6_RS02090 aa29b46c3795e713f94fb71a4fe0b972 297 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 212 279 7.6E-13 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 MKLM6_RS12585 62aea4dad44f6be2b1d53a9a2a4ab84a 218 SUPERFAMILY SSF63380 1 88 1.96E-24 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MKLM6_RS12585 62aea4dad44f6be2b1d53a9a2a4ab84a 218 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 195 3.3E-67 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MKLM6_RS12585 62aea4dad44f6be2b1d53a9a2a4ab84a 218 PIRSF PIRSF000498 1 211 6.4E-77 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MKLM6_RS12585 62aea4dad44f6be2b1d53a9a2a4ab84a 218 SUPERFAMILY SSF63380 93 196 6.38E-35 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MKLM6_RS12585 62aea4dad44f6be2b1d53a9a2a4ab84a 218 Pfam PF00677 Lumazine binding domain 100 184 3.7E-27 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MKLM6_RS12585 62aea4dad44f6be2b1d53a9a2a4ab84a 218 Pfam PF00677 Lumazine binding domain 3 86 5.0E-21 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MKLM6_RS12585 62aea4dad44f6be2b1d53a9a2a4ab84a 218 Gene3D G3DSA:2.40.30.20 94 191 3.9E-37 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS12585 62aea4dad44f6be2b1d53a9a2a4ab84a 218 Gene3D G3DSA:2.40.30.20 1 89 4.9E-28 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MKLM6_RS09745 d2168e36c4159a0687e6d489a57d4360 655 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 325 648 2.7E-134 T 28-03-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 MKLM6_RS09745 d2168e36c4159a0687e6d489a57d4360 655 Gene3D G3DSA:1.50.10.20 50 312 5.8E-58 T 28-03-2018 MKLM6_RS09745 d2168e36c4159a0687e6d489a57d4360 655 SUPERFAMILY SSF48239 255 276 1.8E-94 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid MKLM6_RS09745 d2168e36c4159a0687e6d489a57d4360 655 SUPERFAMILY SSF48239 321 648 1.8E-94 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid MKLM6_RS09745 d2168e36c4159a0687e6d489a57d4360 655 Gene3D G3DSA:1.50.10.20 313 654 2.5E-103 T 28-03-2018 MKLM6_RS09745 d2168e36c4159a0687e6d489a57d4360 655 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 29 316 4.4E-106 T 28-03-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 MKLM6_RS09745 d2168e36c4159a0687e6d489a57d4360 655 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 28 648 7.3E-205 T 28-03-2018 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 MKLM6_RS09745 d2168e36c4159a0687e6d489a57d4360 655 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 25 652 4.2E-275 T 28-03-2018 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00030+4.2.1.12|KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072 MKLM6_RS09745 d2168e36c4159a0687e6d489a57d4360 655 SUPERFAMILY SSF48239 53 321 4.97E-66 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid MKLM6_RS09350 8deff7c220c54adcc1dfc90f178db9d8 267 Pfam PF01564 Spermine/spermidine synthase domain 53 179 1.6E-8 T 28-03-2018 MKLM6_RS09350 8deff7c220c54adcc1dfc90f178db9d8 267 Gene3D G3DSA:3.40.50.150 8 240 1.1E-18 T 28-03-2018 MKLM6_RS09350 8deff7c220c54adcc1dfc90f178db9d8 267 SUPERFAMILY SSF53335 5 229 3.04E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS12440 73b94c2cceceb714e3f258b4a4e54b71 140 SUPERFAMILY SSF54197 1 135 2.89E-31 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 MKLM6_RS12440 73b94c2cceceb714e3f258b4a4e54b71 140 Gene3D G3DSA:3.30.428.10 2 137 6.2E-19 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 MKLM6_RS12440 73b94c2cceceb714e3f258b4a4e54b71 140 PIRSF PIRSF000714 3 137 2.9E-48 T 28-03-2018 IPR026026 Histidine triad hydrolase, Hint-type MKLM6_RS12440 73b94c2cceceb714e3f258b4a4e54b71 140 Pfam PF01230 HIT domain 11 100 1.1E-14 T 28-03-2018 IPR001310 Histidine triad (HIT) protein MKLM6_RS22320 b6b83a9fc2d576cd3ac38ac4ffa31b51 418 Pfam PF00149 Calcineurin-like phosphoesterase 2 195 1.8E-11 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MKLM6_RS22320 b6b83a9fc2d576cd3ac38ac4ffa31b51 418 SUPERFAMILY SSF56300 2 301 1.36E-49 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS22320 b6b83a9fc2d576cd3ac38ac4ffa31b51 418 Gene3D G3DSA:3.60.21.10 1 69 9.1E-10 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS22320 b6b83a9fc2d576cd3ac38ac4ffa31b51 418 Gene3D G3DSA:3.60.21.10 70 247 2.0E-15 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS22320 b6b83a9fc2d576cd3ac38ac4ffa31b51 418 PIRSF PIRSF033091 1 396 1.8E-102 T 28-03-2018 IPR014576 Predicted phosphoesterase, YhaO type MKLM6_RS02160 aa2df09ff57747333891eb87bc3d80cf 347 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 25 265 1.2E-67 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MKLM6_RS02160 aa2df09ff57747333891eb87bc3d80cf 347 Gene3D G3DSA:2.40.50.100 44 175 5.9E-14 T 28-03-2018 MKLM6_RS02160 aa2df09ff57747333891eb87bc3d80cf 347 SUPERFAMILY SSF111369 39 269 1.57E-21 T 28-03-2018 MKLM6_RS02160 aa2df09ff57747333891eb87bc3d80cf 347 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 16 339 2.9E-52 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MKLM6_RS02160 aa2df09ff57747333891eb87bc3d80cf 347 Gene3D G3DSA:2.40.50.100 176 317 0.19 T 28-03-2018 MKLM6_RS14960 a7f8d3b5b6114c1d560b6ed6abd84492 428 SUPERFAMILY SSF56935 375 428 3.53E-10 T 28-03-2018 MKLM6_RS14960 a7f8d3b5b6114c1d560b6ed6abd84492 428 SUPERFAMILY SSF56935 86 339 3.53E-10 T 28-03-2018 MKLM6_RS14960 a7f8d3b5b6114c1d560b6ed6abd84492 428 SUPERFAMILY SSF56935 36 58 3.53E-10 T 28-03-2018 MKLM6_RS14960 a7f8d3b5b6114c1d560b6ed6abd84492 428 Gene3D G3DSA:2.40.160.10 26 428 1.9E-18 T 28-03-2018 MKLM6_RS14960 a7f8d3b5b6114c1d560b6ed6abd84492 428 Pfam PF07642 Putative beta-barrel porin-2, OmpL-like. bbp2 38 428 2.5E-92 T 28-03-2018 IPR011486 Putative beta-barrel porin-2, OmpL-like. bbp2 MKLM6_RS06935 dee9625e1030c90722375ef18ca8b84c 303 SUPERFAMILY SSF53850 43 276 1.19E-16 T 28-03-2018 MKLM6_RS06935 dee9625e1030c90722375ef18ca8b84c 303 Gene3D G3DSA:3.40.190.10 132 279 2.3E-22 T 28-03-2018 MKLM6_RS06935 dee9625e1030c90722375ef18ca8b84c 303 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 45 283 5.9E-47 T 28-03-2018 MKLM6_RS07505 5665c0cdd2196846d6b961064412b4f2 414 Gene3D G3DSA:1.20.5.730 377 411 0.38 T 28-03-2018 MKLM6_RS07505 5665c0cdd2196846d6b961064412b4f2 414 SUPERFAMILY SSF116734 3 209 1.01E-42 T 28-03-2018 MKLM6_RS07505 5665c0cdd2196846d6b961064412b4f2 414 Gene3D G3DSA:3.90.220.20 182 376 1.1E-36 T 28-03-2018 MKLM6_RS07505 5665c0cdd2196846d6b961064412b4f2 414 Gene3D G3DSA:3.90.220.20 1 181 9.3E-33 T 28-03-2018 MKLM6_RS07505 5665c0cdd2196846d6b961064412b4f2 414 Pfam PF01420 Type I restriction modification DNA specificity domain 210 391 2.9E-18 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MKLM6_RS07505 5665c0cdd2196846d6b961064412b4f2 414 Pfam PF01420 Type I restriction modification DNA specificity domain 5 178 5.5E-16 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MKLM6_RS07505 5665c0cdd2196846d6b961064412b4f2 414 SUPERFAMILY SSF116734 201 409 7.52E-45 T 28-03-2018 MKLM6_RS09320 53cfe53ece31ccdb78848ee155449a77 136 Pfam PF05523 WxcM-like, C-terminal 5 133 5.2E-58 T 28-03-2018 IPR008894 WxcM-like, C-terminal KEGG: 00523+5.3.2.3|MetaCyc: PWY-6953|MetaCyc: PWY-7688 MKLM6_RS09320 53cfe53ece31ccdb78848ee155449a77 136 SUPERFAMILY SSF51182 5 131 1.4E-44 T 28-03-2018 IPR011051 RmlC-like cupin domain MKLM6_RS09320 53cfe53ece31ccdb78848ee155449a77 136 Gene3D G3DSA:2.60.120.10 2 136 5.2E-33 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS22770 c1b7d3dcc18c8ebcee506e35f620dfc0 266 Gene3D G3DSA:2.40.70.10 95 206 2.6E-16 T 28-03-2018 IPR021109 Aspartic peptidase domain MKLM6_RS22770 c1b7d3dcc18c8ebcee506e35f620dfc0 266 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 116 127 - T 28-03-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 MKLM6_RS22770 c1b7d3dcc18c8ebcee506e35f620dfc0 266 TIGRFAM TIGR02281 clan_AA_DTGA: clan AA aspartic protease, TIGR02281 family 94 204 1.6E-19 T 28-03-2018 IPR011969 Clan AA aspartic peptidase, C-terminal MKLM6_RS22770 c1b7d3dcc18c8ebcee506e35f620dfc0 266 Pfam PF13975 gag-polyprotein putative aspartyl protease 107 191 6.1E-19 T 28-03-2018 MKLM6_RS22770 c1b7d3dcc18c8ebcee506e35f620dfc0 266 SUPERFAMILY SSF50630 96 195 4.33E-17 T 28-03-2018 IPR021109 Aspartic peptidase domain MKLM6_RS11330 f04fbdf02709e4dc18c6f6647ee22034 766 PRINTS PR00811 Bacterial general secretion pathway protein D signature 554 578 1.4E-16 T 28-03-2018 IPR001775 GspD/PilQ family MKLM6_RS11330 f04fbdf02709e4dc18c6f6647ee22034 766 PRINTS PR00811 Bacterial general secretion pathway protein D signature 481 491 1.4E-16 T 28-03-2018 IPR001775 GspD/PilQ family MKLM6_RS11330 f04fbdf02709e4dc18c6f6647ee22034 766 PRINTS PR00811 Bacterial general secretion pathway protein D signature 693 711 1.4E-16 T 28-03-2018 IPR001775 GspD/PilQ family MKLM6_RS11330 f04fbdf02709e4dc18c6f6647ee22034 766 PRINTS PR00811 Bacterial general secretion pathway protein D signature 716 730 1.4E-16 T 28-03-2018 IPR001775 GspD/PilQ family MKLM6_RS11330 f04fbdf02709e4dc18c6f6647ee22034 766 Pfam PF00263 Bacterial type II and III secretion system protein 560 728 3.5E-47 T 28-03-2018 IPR004846 Type II/III secretion system GO:0009306 MKLM6_RS11330 f04fbdf02709e4dc18c6f6647ee22034 766 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 93 738 7.2E-160 T 28-03-2018 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 MKLM6_RS11330 f04fbdf02709e4dc18c6f6647ee22034 766 Pfam PF03958 Bacterial type II/III secretion system short domain 189 247 4.3E-7 T 28-03-2018 IPR005644 NolW-like MKLM6_RS11330 f04fbdf02709e4dc18c6f6647ee22034 766 Pfam PF03958 Bacterial type II/III secretion system short domain 331 480 2.1E-9 T 28-03-2018 IPR005644 NolW-like MKLM6_RS09670 e1bc7f7a7158f044b7cef3fabcef81bd 76 Pfam PF05957 Bacterial protein of unknown function (DUF883) 3 76 3.2E-10 T 28-03-2018 IPR010279 Protein of unknown function DUF883, ElaB MKLM6_RS20405 b514999cfe6d7a0b657316fc7aa481b9 207 Gene3D G3DSA:1.10.287.540 57 92 2.6E-13 T 28-03-2018 MKLM6_RS20405 b514999cfe6d7a0b657316fc7aa481b9 207 PIRSF PIRSF016482 1 205 1.4E-56 T 28-03-2018 IPR007445 Pilus assembly protein, PilO MKLM6_RS20405 b514999cfe6d7a0b657316fc7aa481b9 207 Pfam PF04350 Pilus assembly protein, PilO 48 189 1.8E-49 T 28-03-2018 IPR007445 Pilus assembly protein, PilO MKLM6_RS20405 b514999cfe6d7a0b657316fc7aa481b9 207 Gene3D G3DSA:3.30.70.60 93 203 2.1E-25 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 MKLM6_RS08895 0c9ada4fa96211c063bee4fc246f5437 795 SUPERFAMILY SSF52402 502 628 5.16E-5 T 28-03-2018 MKLM6_RS08895 0c9ada4fa96211c063bee4fc246f5437 795 Gene3D G3DSA:3.40.50.620 500 628 1.9E-5 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS08895 0c9ada4fa96211c063bee4fc246f5437 795 Gene3D G3DSA:3.40.50.620 629 775 3.6E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS08895 0c9ada4fa96211c063bee4fc246f5437 795 Pfam PF00916 Sulfate permease family 60 446 7.3E-57 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MKLM6_RS08895 0c9ada4fa96211c063bee4fc246f5437 795 SUPERFAMILY SSF52402 634 771 1.09E-24 T 28-03-2018 MKLM6_RS08895 0c9ada4fa96211c063bee4fc246f5437 795 Pfam PF00582 Universal stress protein family 634 769 3.0E-18 T 28-03-2018 IPR006016 UspA GO:0006950 MKLM6_RS08895 0c9ada4fa96211c063bee4fc246f5437 795 PRINTS PR01438 Universal stress protein signature 747 769 1.8E-12 T 28-03-2018 IPR006015 Universal stress protein A MKLM6_RS08895 0c9ada4fa96211c063bee4fc246f5437 795 PRINTS PR01438 Universal stress protein signature 729 741 1.8E-12 T 28-03-2018 IPR006015 Universal stress protein A MKLM6_RS08895 0c9ada4fa96211c063bee4fc246f5437 795 PRINTS PR01438 Universal stress protein signature 634 652 1.8E-12 T 28-03-2018 IPR006015 Universal stress protein A MKLM6_RS02725 51a51c25ecc3205bad79b5ea01d0148a 240 Pfam PF00813 FliP family 42 234 5.7E-78 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MKLM6_RS02725 51a51c25ecc3205bad79b5ea01d0148a 240 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 59 79 1.0E-64 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MKLM6_RS02725 51a51c25ecc3205bad79b5ea01d0148a 240 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 40 59 1.0E-64 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MKLM6_RS02725 51a51c25ecc3205bad79b5ea01d0148a 240 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 79 98 1.0E-64 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MKLM6_RS02725 51a51c25ecc3205bad79b5ea01d0148a 240 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 167 187 1.0E-64 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MKLM6_RS02725 51a51c25ecc3205bad79b5ea01d0148a 240 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 188 209 1.0E-64 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MKLM6_RS02725 51a51c25ecc3205bad79b5ea01d0148a 240 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 212 237 1.0E-64 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MKLM6_RS02725 51a51c25ecc3205bad79b5ea01d0148a 240 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 98 110 1.2E-18 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MKLM6_RS02725 51a51c25ecc3205bad79b5ea01d0148a 240 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 38 47 1.2E-18 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MKLM6_RS02725 51a51c25ecc3205bad79b5ea01d0148a 240 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 228 238 1.2E-18 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MKLM6_RS02725 51a51c25ecc3205bad79b5ea01d0148a 240 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 110 124 1.2E-18 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MKLM6_RS02725 51a51c25ecc3205bad79b5ea01d0148a 240 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 160 172 1.2E-18 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MKLM6_RS02725 51a51c25ecc3205bad79b5ea01d0148a 240 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 138 150 1.2E-18 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MKLM6_RS02725 51a51c25ecc3205bad79b5ea01d0148a 240 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 42 238 2.7E-81 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MKLM6_RS02725 51a51c25ecc3205bad79b5ea01d0148a 240 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 167 182 - T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MKLM6_RS02725 51a51c25ecc3205bad79b5ea01d0148a 240 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 215 227 - T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MKLM6_RS20395 fd44548e4f614a2684a97cc7def3342b 749 TIGRFAM TIGR02515 IV_pilus_PilQ: type IV pilus secretin PilQ 291 743 2.2E-147 T 28-03-2018 IPR013355 Type IV pilus secretin PilQ MKLM6_RS20395 fd44548e4f614a2684a97cc7def3342b 749 Pfam PF11741 AMIN domain 51 133 1.6E-10 T 28-03-2018 IPR021731 AMIN domain MKLM6_RS20395 fd44548e4f614a2684a97cc7def3342b 749 Pfam PF00263 Bacterial type II and III secretion system protein 584 743 2.6E-46 T 28-03-2018 IPR004846 Type II/III secretion system GO:0009306 MKLM6_RS20395 fd44548e4f614a2684a97cc7def3342b 749 SMART SM00965 316 364 2.5E-10 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MKLM6_RS20395 fd44548e4f614a2684a97cc7def3342b 749 Pfam PF07660 Secretin and TonB N terminus short domain 317 363 2.4E-9 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MKLM6_RS20395 fd44548e4f614a2684a97cc7def3342b 749 PRINTS PR00811 Bacterial general secretion pathway protein D signature 707 725 2.6E-17 T 28-03-2018 IPR001775 GspD/PilQ family MKLM6_RS20395 fd44548e4f614a2684a97cc7def3342b 749 PRINTS PR00811 Bacterial general secretion pathway protein D signature 499 509 2.6E-17 T 28-03-2018 IPR001775 GspD/PilQ family MKLM6_RS20395 fd44548e4f614a2684a97cc7def3342b 749 PRINTS PR00811 Bacterial general secretion pathway protein D signature 580 604 2.6E-17 T 28-03-2018 IPR001775 GspD/PilQ family MKLM6_RS20395 fd44548e4f614a2684a97cc7def3342b 749 PRINTS PR00811 Bacterial general secretion pathway protein D signature 615 625 2.6E-17 T 28-03-2018 IPR001775 GspD/PilQ family MKLM6_RS20395 fd44548e4f614a2684a97cc7def3342b 749 PRINTS PR00811 Bacterial general secretion pathway protein D signature 730 744 2.6E-17 T 28-03-2018 IPR001775 GspD/PilQ family MKLM6_RS20395 fd44548e4f614a2684a97cc7def3342b 749 Pfam PF03958 Bacterial type II/III secretion system short domain 390 499 2.9E-13 T 28-03-2018 IPR005644 NolW-like MKLM6_RS11580 321cf2ca4ab88068f93cddba5536753b 419 Gene3D G3DSA:1.10.150.130 112 222 6.7E-15 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal MKLM6_RS11580 321cf2ca4ab88068f93cddba5536753b 419 Pfam PF00589 Phage integrase family 223 384 2.7E-21 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS11580 321cf2ca4ab88068f93cddba5536753b 419 Pfam PF13356 Arm DNA-binding domain 6 90 8.4E-17 T 28-03-2018 IPR025166 Integrase, DNA-binding domain MKLM6_RS11580 321cf2ca4ab88068f93cddba5536753b 419 Gene3D G3DSA:1.10.443.10 223 390 5.3E-23 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS11580 321cf2ca4ab88068f93cddba5536753b 419 SUPERFAMILY SSF56349 114 397 5.59E-58 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS19745 8fb66aabe82ec3b5f9bc45ef67120320 414 Pfam PF10592 AIPR protein 78 341 1.8E-31 T 28-03-2018 IPR018891 Abortive bacteriophage infection, resistance MKLM6_RS14295 f69f933379d7b6b6a3beaa3df05bab4e 192 SUPERFAMILY SSF55166 50 177 3.4E-29 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MKLM6_RS14295 f69f933379d7b6b6a3beaa3df05bab4e 192 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 54 177 5.3E-36 T 28-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 MKLM6_RS14295 f69f933379d7b6b6a3beaa3df05bab4e 192 Gene3D G3DSA:3.30.1380.10 15 176 1.3E-31 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MKLM6_RS18435 4e4653203a86b255d00c4ae000eef0e0 206 Pfam PF00573 Ribosomal protein L4/L1 family 18 204 7.5E-58 T 28-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18435 4e4653203a86b255d00c4ae000eef0e0 206 SUPERFAMILY SSF52166 13 205 3.92E-63 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18435 4e4653203a86b255d00c4ae000eef0e0 206 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 18 203 1.9E-66 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18435 4e4653203a86b255d00c4ae000eef0e0 206 Gene3D G3DSA:3.40.1370.10 147 204 2.0E-11 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18435 4e4653203a86b255d00c4ae000eef0e0 206 Gene3D G3DSA:3.40.1370.10 1 146 8.2E-40 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 MKLM6_RS18435 4e4653203a86b255d00c4ae000eef0e0 206 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 206 30.905 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS21430 b591f8e30fee75332470239ae4e49b5a 163 Gene3D G3DSA:2.40.40.10 40 156 3.3E-19 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain MKLM6_RS21430 b591f8e30fee75332470239ae4e49b5a 163 Pfam PF03330 Lytic transglycolase 68 153 1.0E-22 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain MKLM6_RS21430 b591f8e30fee75332470239ae4e49b5a 163 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 69 160 2.8E-34 T 28-03-2018 IPR012997 Rare lipoprotein A MKLM6_RS21430 b591f8e30fee75332470239ae4e49b5a 163 SUPERFAMILY SSF50685 77 147 2.41E-8 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain MKLM6_RS21430 b591f8e30fee75332470239ae4e49b5a 163 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 13 156 22.126 T 28-03-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 MKLM6_RS02390 96e77868f4c11663e17bd08fbb94499f 89 Gene3D G3DSA:3.30.2020.10 1 79 1.6E-17 T 28-03-2018 IPR018841 Protein of unknown function DUF2442 MKLM6_RS02390 96e77868f4c11663e17bd08fbb94499f 89 SUPERFAMILY SSF143880 1 80 8.89E-14 T 28-03-2018 IPR018841 Protein of unknown function DUF2442 MKLM6_RS02390 96e77868f4c11663e17bd08fbb94499f 89 Pfam PF10387 Protein of unknown function (DUF2442) 4 74 4.5E-10 T 28-03-2018 IPR018841 Protein of unknown function DUF2442 MKLM6_RS04515 5d9843b005ebbcda9c4e98df860c449e 157 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3 157 5.4E-73 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MKLM6_RS04515 5d9843b005ebbcda9c4e98df860c449e 157 SUPERFAMILY SSF69765 1 156 9.94E-68 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MKLM6_RS04515 5d9843b005ebbcda9c4e98df860c449e 157 Gene3D G3DSA:3.30.1330.50 1 157 5.9E-75 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MKLM6_RS04515 5d9843b005ebbcda9c4e98df860c449e 157 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 2 157 36.966 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MKLM6_RS04515 5d9843b005ebbcda9c4e98df860c449e 157 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 36 51 - T 28-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MKLM6_RS04515 5d9843b005ebbcda9c4e98df860c449e 157 Pfam PF02542 YgbB family 2 156 3.8E-69 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MKLM6_RS18860 101e4b5b8fe185a51d036d9fb659d5b5 162 Pfam PF04093 rod shape-determining protein MreD 11 154 3.2E-22 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 MKLM6_RS18860 101e4b5b8fe185a51d036d9fb659d5b5 162 PIRSF PIRSF018472 1 162 4.8E-44 T 28-03-2018 IPR026034 Cell shape-determining protein MreD, proteobacterial type MKLM6_RS18860 101e4b5b8fe185a51d036d9fb659d5b5 162 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 12 153 3.7E-31 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 MKLM6_RS15850 6e1458bff2f2abf789caa10c9e9aee7f 297 Gene3D G3DSA:3.20.20.100 1 278 3.6E-35 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain MKLM6_RS15850 6e1458bff2f2abf789caa10c9e9aee7f 297 Pfam PF00248 Aldo/keto reductase family 2 276 3.3E-27 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain MKLM6_RS15850 6e1458bff2f2abf789caa10c9e9aee7f 297 SUPERFAMILY SSF51430 2 275 1.44E-41 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain MKLM6_RS07910 7f064dc2d66e053c65b3fb9037ba1b2c 142 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 2 23 2.2E-5 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal MKLM6_RS07910 7f064dc2d66e053c65b3fb9037ba1b2c 142 SUPERFAMILY SSF49367 44 142 1.83E-12 T 28-03-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 MKLM6_RS07910 7f064dc2d66e053c65b3fb9037ba1b2c 142 Pfam PF01880 Desulfoferrodoxin 51 138 1.2E-8 T 28-03-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 MKLM6_RS07910 7f064dc2d66e053c65b3fb9037ba1b2c 142 Gene3D G3DSA:2.60.40.730 36 142 4.1E-18 T 28-03-2018 MKLM6_RS09955 9c4af89ea11bc4e864c8c98dfa08f844 501 Gene3D G3DSA:3.40.50.200 37 336 3.1E-11 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MKLM6_RS09955 9c4af89ea11bc4e864c8c98dfa08f844 501 Gene3D G3DSA:2.60.120.380 362 463 3.9E-8 T 28-03-2018 MKLM6_RS09955 9c4af89ea11bc4e864c8c98dfa08f844 501 SUPERFAMILY SSF52743 74 331 9.69E-11 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MKLM6_RS19915 d7a5037a32fc11fdee9c171029b3642b 166 Pfam PF03968 OstA-like protein 30 139 2.8E-22 T 28-03-2018 IPR005653 Organic solvent tolerance-like, N-terminal MKLM6_RS19915 d7a5037a32fc11fdee9c171029b3642b 166 Gene3D G3DSA:2.60.450.10 20 158 1.6E-23 T 28-03-2018 MKLM6_RS19915 d7a5037a32fc11fdee9c171029b3642b 166 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 21 161 8.6E-40 T 28-03-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 MKLM6_RS19915 d7a5037a32fc11fdee9c171029b3642b 166 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 1 161 23.05 T 28-03-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 MKLM6_RS13890 b111983aeb1ec4838a3b4a6db9ed407c 355 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 9 318 50.248 T 28-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 MKLM6_RS13890 b111983aeb1ec4838a3b4a6db9ed407c 355 Pfam PF13484 4Fe-4S double cluster binding domain 195 259 2.3E-19 T 28-03-2018 MKLM6_RS13890 b111983aeb1ec4838a3b4a6db9ed407c 355 Gene3D G3DSA:3.30.70.20 202 305 1.7E-10 T 28-03-2018 MKLM6_RS13890 b111983aeb1ec4838a3b4a6db9ed407c 355 Pfam PF08331 Domain of unknown function (DUF1730) 64 143 3.3E-22 T 28-03-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 MKLM6_RS13890 b111983aeb1ec4838a3b4a6db9ed407c 355 Gene3D G3DSA:3.30.70.20 67 201 4.2E-4 T 28-03-2018 MKLM6_RS13890 b111983aeb1ec4838a3b4a6db9ed407c 355 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 196 207 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MKLM6_RS13890 b111983aeb1ec4838a3b4a6db9ed407c 355 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 16 351 1.4E-152 T 28-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 MKLM6_RS13890 b111983aeb1ec4838a3b4a6db9ed407c 355 SUPERFAMILY SSF46548 142 259 3.66E-19 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MKLM6_RS06900 47f8199242829c1f149a4b9b02776d91 330 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 97 115 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 MKLM6_RS06900 47f8199242829c1f149a4b9b02776d91 330 Pfam PF01207 Dihydrouridine synthase (Dus) 18 314 1.4E-86 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MKLM6_RS06900 47f8199242829c1f149a4b9b02776d91 330 PIRSF PIRSF006621 9 314 3.3E-76 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MKLM6_RS06900 47f8199242829c1f149a4b9b02776d91 330 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 10 330 50.859 T 28-03-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 MKLM6_RS06900 47f8199242829c1f149a4b9b02776d91 330 TIGRFAM TIGR00742 yjbN: tRNA dihydrouridine synthase A 15 328 6.7E-143 T 28-03-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 MKLM6_RS06900 47f8199242829c1f149a4b9b02776d91 330 SUPERFAMILY SSF51395 15 313 3.71E-73 T 28-03-2018 MKLM6_RS06900 47f8199242829c1f149a4b9b02776d91 330 Gene3D G3DSA:3.20.20.70 12 253 1.2E-43 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS21420 190a15e802135ba3f754a882612b17e9 188 Pfam PF13761 Domain of unknown function (DUF4166) 12 185 7.5E-38 T 28-03-2018 IPR025311 Domain of unknown function DUF4166 MKLM6_RS03920 c6361a3fe2de09b05ecfaa9ec758b139 232 Pfam PF06508 Queuosine biosynthesis protein QueC 12 221 2.9E-78 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MKLM6_RS03920 c6361a3fe2de09b05ecfaa9ec758b139 232 Gene3D G3DSA:3.40.50.620 8 232 4.0E-53 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS03920 c6361a3fe2de09b05ecfaa9ec758b139 232 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 10 227 55.934 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MKLM6_RS03920 c6361a3fe2de09b05ecfaa9ec758b139 232 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 12 214 1.1E-61 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MKLM6_RS03920 c6361a3fe2de09b05ecfaa9ec758b139 232 SUPERFAMILY SSF52402 10 231 7.5E-63 T 28-03-2018 MKLM6_RS03920 c6361a3fe2de09b05ecfaa9ec758b139 232 PIRSF PIRSF006293 9 232 3.5E-79 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MKLM6_RS03605 4a30324ce844321570d51bb0e9889c11 239 Gene3D G3DSA:3.30.70.270 58 229 6.6E-60 T 28-03-2018 MKLM6_RS03605 4a30324ce844321570d51bb0e9889c11 239 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 69 224 4.8E-46 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS03605 4a30324ce844321570d51bb0e9889c11 239 SUPERFAMILY SSF55073 74 222 6.28E-49 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS03605 4a30324ce844321570d51bb0e9889c11 239 SMART SM00267 58 228 3.9E-61 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS03605 4a30324ce844321570d51bb0e9889c11 239 Pfam PF00990 Diguanylate cyclase, GGDEF domain 69 222 4.4E-53 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS06155 e76aca6f9ce075af13dc081f149b5ea6 488 Gene3D G3DSA:3.40.50.300 169 354 5.4E-10 T 28-03-2018 MKLM6_RS06155 e76aca6f9ce075af13dc081f149b5ea6 488 SUPERFAMILY SSF52540 197 332 1.6E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS06250 6e5111a6d3cce9ac18d8cadf43574adc 365 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 79 283 1.5E-18 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MKLM6_RS06250 6e5111a6d3cce9ac18d8cadf43574adc 365 SUPERFAMILY SSF111369 73 285 2.09E-20 T 28-03-2018 MKLM6_RS06250 6e5111a6d3cce9ac18d8cadf43574adc 365 Gene3D G3DSA:2.40.50.100 80 152 2.4E-15 T 28-03-2018 MKLM6_RS06250 6e5111a6d3cce9ac18d8cadf43574adc 365 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 63 361 2.5E-61 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MKLM6_RS06250 6e5111a6d3cce9ac18d8cadf43574adc 365 Gene3D G3DSA:2.40.50.100 186 332 0.0038 T 28-03-2018 MKLM6_RS18345 81de4fc7f739c9954ea29cd26d9678d8 144 Gene3D G3DSA:3.100.10.10 41 144 3.8E-22 T 28-03-2018 MKLM6_RS18345 81de4fc7f739c9954ea29cd26d9678d8 144 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 144 18.049 T 28-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 MKLM6_RS18345 81de4fc7f739c9954ea29cd26d9678d8 144 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 143 2.4E-28 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P MKLM6_RS18345 81de4fc7f739c9954ea29cd26d9678d8 144 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 3 143 1.5E-42 T 28-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS18345 81de4fc7f739c9954ea29cd26d9678d8 144 SUPERFAMILY SSF52080 4 143 1.26E-41 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P MKLM6_RS22310 c4bbc4ebd4a0284a59a46c9b284324c9 849 Pfam PF08665 PglZ domain 455 631 4.9E-62 T 28-03-2018 IPR013973 PglZ domain MKLM6_RS22310 c4bbc4ebd4a0284a59a46c9b284324c9 849 SUPERFAMILY SSF53649 454 634 6.8E-6 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MKLM6_RS22310 c4bbc4ebd4a0284a59a46c9b284324c9 849 TIGRFAM TIGR02687 TIGR02687: TIGR02687 family protein 5 834 0.0 T 28-03-2018 IPR014060 Conserved hypothetical protein CHP02687 MKLM6_RS22310 c4bbc4ebd4a0284a59a46c9b284324c9 849 Gene3D G3DSA:3.40.720.10 418 646 4.1E-5 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MKLM6_RS08035 f86b0c8363303a3a71b38487b02a778c 412 Gene3D G3DSA:3.40.50.1820 69 377 6.9E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS08035 f86b0c8363303a3a71b38487b02a778c 412 SUPERFAMILY SSF53474 79 270 3.4E-7 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS03695 f8f5de5262512dfd40c0bc597224625c 546 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MKLM6_RS03695 f8f5de5262512dfd40c0bc597224625c 546 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 526 2.6E-254 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MKLM6_RS03695 f8f5de5262512dfd40c0bc597224625c 546 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 524 4.5E-95 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 MKLM6_RS03695 f8f5de5262512dfd40c0bc597224625c 546 SUPERFAMILY SSF54849 137 204 6.41E-25 T 28-03-2018 MKLM6_RS03695 f8f5de5262512dfd40c0bc597224625c 546 Gene3D G3DSA:1.10.560.10 374 516 8.5E-25 T 28-03-2018 IPR027413 GroEL-like equatorial domain MKLM6_RS03695 f8f5de5262512dfd40c0bc597224625c 546 Gene3D G3DSA:1.10.560.10 1 183 1.1E-40 T 28-03-2018 IPR027413 GroEL-like equatorial domain MKLM6_RS03695 f8f5de5262512dfd40c0bc597224625c 546 SUPERFAMILY SSF52029 184 376 3.66E-83 T 28-03-2018 IPR027409 GroEL-like apical domain MKLM6_RS03695 f8f5de5262512dfd40c0bc597224625c 546 SUPERFAMILY SSF48592 406 521 1.76E-77 T 28-03-2018 MKLM6_RS03695 f8f5de5262512dfd40c0bc597224625c 546 SUPERFAMILY SSF48592 7 134 1.76E-77 T 28-03-2018 MKLM6_RS03695 f8f5de5262512dfd40c0bc597224625c 546 Gene3D G3DSA:3.50.7.10 184 373 2.8E-97 T 28-03-2018 IPR027409 GroEL-like apical domain MKLM6_RS03695 f8f5de5262512dfd40c0bc597224625c 546 PRINTS PR00298 60kDa chaperonin signature 350 375 1.6E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MKLM6_RS03695 f8f5de5262512dfd40c0bc597224625c 546 PRINTS PR00298 60kDa chaperonin signature 398 419 1.6E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MKLM6_RS03695 f8f5de5262512dfd40c0bc597224625c 546 PRINTS PR00298 60kDa chaperonin signature 27 53 1.6E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MKLM6_RS03695 f8f5de5262512dfd40c0bc597224625c 546 PRINTS PR00298 60kDa chaperonin signature 83 110 1.6E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MKLM6_RS03695 f8f5de5262512dfd40c0bc597224625c 546 PRINTS PR00298 60kDa chaperonin signature 268 291 1.6E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MKLM6_RS03695 f8f5de5262512dfd40c0bc597224625c 546 Hamap MF_00600 60 kDa chaperonin [groL]. 2 545 41.489 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MKLM6_RS05760 6645acf1c74e047b03a0648e0bb77c03 690 Pfam PF07715 TonB-dependent Receptor Plug Domain 39 144 3.2E-20 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS05760 6645acf1c74e047b03a0648e0bb77c03 690 Gene3D G3DSA:2.170.130.10 17 151 4.4E-23 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS05760 6645acf1c74e047b03a0648e0bb77c03 690 Gene3D G3DSA:2.40.170.20 155 689 1.1E-40 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS05760 6645acf1c74e047b03a0648e0bb77c03 690 Pfam PF00593 TonB dependent receptor 244 688 3.2E-35 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS05760 6645acf1c74e047b03a0648e0bb77c03 690 SUPERFAMILY SSF56935 27 689 1.14E-86 T 28-03-2018 MKLM6_RS18490 6893c889113b0eeccd9915fff0db4c95 231 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 28-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18490 6893c889113b0eeccd9915fff0db4c95 231 SUPERFAMILY SSF56808 6 225 1.31E-82 T 28-03-2018 IPR023674 Ribosomal protein L1-like MKLM6_RS18490 6893c889113b0eeccd9915fff0db4c95 231 Pfam PF00687 Ribosomal protein L1p/L10e family 30 220 4.8E-53 T 28-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein MKLM6_RS18490 6893c889113b0eeccd9915fff0db4c95 231 Gene3D G3DSA:3.30.190.20 150 228 8.1E-21 T 28-03-2018 MKLM6_RS18490 6893c889113b0eeccd9915fff0db4c95 231 PIRSF PIRSF002155 1 227 3.1E-80 T 28-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18490 6893c889113b0eeccd9915fff0db4c95 231 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 9.4E-107 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 MKLM6_RS18490 6893c889113b0eeccd9915fff0db4c95 231 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 43.514 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 MKLM6_RS18490 6893c889113b0eeccd9915fff0db4c95 231 Gene3D G3DSA:3.40.50.790 68 149 4.3E-35 T 28-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich MKLM6_RS12455 4b2a6a3bff6b022e10c66e9783cfdca4 184 Pfam PF00156 Phosphoribosyl transferase domain 20 166 2.1E-22 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MKLM6_RS12455 4b2a6a3bff6b022e10c66e9783cfdca4 184 Gene3D G3DSA:3.40.50.2020 14 184 2.8E-36 T 28-03-2018 MKLM6_RS12455 4b2a6a3bff6b022e10c66e9783cfdca4 184 SUPERFAMILY SSF53271 15 181 7.6E-47 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like MKLM6_RS14635 ab1d2e0628daf97dec67a501d0af892f 264 SMART SM00052 19 255 8.3E-27 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14635 ab1d2e0628daf97dec67a501d0af892f 264 Gene3D G3DSA:3.20.20.450 12 254 7.6E-51 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14635 ab1d2e0628daf97dec67a501d0af892f 264 SUPERFAMILY SSF141868 33 251 1.31E-56 T 28-03-2018 IPR001633 EAL domain MKLM6_RS14635 ab1d2e0628daf97dec67a501d0af892f 264 Pfam PF00563 EAL domain 33 250 9.2E-45 T 28-03-2018 IPR001633 EAL domain MKLM6_RS10590 00ffada54f2b5b758355b35c33803f15 313 PIRSF PIRSF006487 159 278 2.4 T 28-03-2018 MKLM6_RS10590 00ffada54f2b5b758355b35c33803f15 313 PIRSF PIRSF006487 11 125 8.8E-7 T 28-03-2018 MKLM6_RS10590 00ffada54f2b5b758355b35c33803f15 313 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 183 246 8.5E-27 T 28-03-2018 IPR017703 YgfZ/GcvT conserved site MKLM6_RS10590 00ffada54f2b5b758355b35c33803f15 313 Pfam PF01571 Aminomethyltransferase folate-binding domain 26 121 6.3E-10 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal MKLM6_RS10590 00ffada54f2b5b758355b35c33803f15 313 SUPERFAMILY SSF103025 25 238 1.15E-50 T 28-03-2018 MKLM6_RS10590 00ffada54f2b5b758355b35c33803f15 313 Gene3D G3DSA:3.30.70.1400 26 235 1.4E-27 T 28-03-2018 MKLM6_RS01695 5bf38c58a2beb53d5d47482c681329f5 252 Gene3D G3DSA:3.40.1130.10 44 252 4.5E-38 T 28-03-2018 MKLM6_RS01695 5bf38c58a2beb53d5d47482c681329f5 252 SUPERFAMILY SSF69593 20 243 8.37E-39 T 28-03-2018 MKLM6_RS01695 5bf38c58a2beb53d5d47482c681329f5 252 Pfam PF01553 Acyltransferase 72 196 1.1E-18 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MKLM6_RS01695 5bf38c58a2beb53d5d47482c681329f5 252 SMART SM00563 85 199 2.0E-21 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MKLM6_RS10750 60d76824ef31aab065081ca27b3d2c7c 436 SUPERFAMILY SSF55874 312 436 1.96E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS10750 60d76824ef31aab065081ca27b3d2c7c 436 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 347 435 1.1E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS10750 60d76824ef31aab065081ca27b3d2c7c 436 Pfam PF07730 Histidine kinase 241 303 1.4E-11 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MKLM6_RS10750 60d76824ef31aab065081ca27b3d2c7c 436 Gene3D G3DSA:3.30.565.10 199 436 4.0E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS10750 60d76824ef31aab065081ca27b3d2c7c 436 Pfam PF16448 LapD/MoxY periplasmic domain 25 147 9.4E-7 T 28-03-2018 IPR032244 LapD/MoxY, periplasmic domain MKLM6_RS10750 60d76824ef31aab065081ca27b3d2c7c 436 SMART SM00304 173 225 6.1E-5 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS02930 ec3afb77c5e9b7ece83916d6f77b4a39 305 Gene3D G3DSA:2.40.160.20 86 305 4.5E-8 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MKLM6_RS02930 ec3afb77c5e9b7ece83916d6f77b4a39 305 SUPERFAMILY SSF56925 143 305 1.26E-6 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MKLM6_RS10725 674adde27d5a95753af71f9229bb03cf 232 SUPERFAMILY SSF48317 14 223 3.66E-19 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MKLM6_RS10725 674adde27d5a95753af71f9229bb03cf 232 SMART SM00014 96 216 0.0069 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MKLM6_RS10725 674adde27d5a95753af71f9229bb03cf 232 Gene3D G3DSA:1.20.144.10 10 232 1.8E-19 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MKLM6_RS10725 674adde27d5a95753af71f9229bb03cf 232 Pfam PF01569 PAP2 superfamily 99 219 2.0E-17 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MKLM6_RS12415 cc36e74cbb181cd3bf28d70f5fb989cb 142 Gene3D G3DSA:2.60.40.790 10 142 9.7E-30 T 28-03-2018 IPR008978 HSP20-like chaperone MKLM6_RS12415 cc36e74cbb181cd3bf28d70f5fb989cb 142 Pfam PF00011 Hsp20/alpha crystallin family 41 134 1.6E-19 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain MKLM6_RS12415 cc36e74cbb181cd3bf28d70f5fb989cb 142 SUPERFAMILY SSF49764 27 141 8.37E-32 T 28-03-2018 IPR008978 HSP20-like chaperone MKLM6_RS10650 33f1d03aa6e08d04c5201419cb9a3405 467 Gene3D G3DSA:2.40.10.10 161 262 9.8E-39 T 28-03-2018 MKLM6_RS10650 33f1d03aa6e08d04c5201419cb9a3405 467 SUPERFAMILY SSF50156 377 466 6.44E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 MKLM6_RS10650 33f1d03aa6e08d04c5201419cb9a3405 467 SUPERFAMILY SSF50156 231 354 2.29E-23 T 28-03-2018 IPR001478 PDZ domain GO:0005515 MKLM6_RS10650 33f1d03aa6e08d04c5201419cb9a3405 467 Pfam PF13180 PDZ domain 262 352 4.6E-16 T 28-03-2018 IPR001478 PDZ domain GO:0005515 MKLM6_RS10650 33f1d03aa6e08d04c5201419cb9a3405 467 Pfam PF13180 PDZ domain 379 457 3.0E-7 T 28-03-2018 IPR001478 PDZ domain GO:0005515 MKLM6_RS10650 33f1d03aa6e08d04c5201419cb9a3405 467 PRINTS PR00834 HtrA/DegQ protease family signature 302 314 2.9E-51 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MKLM6_RS10650 33f1d03aa6e08d04c5201419cb9a3405 467 PRINTS PR00834 HtrA/DegQ protease family signature 120 140 2.9E-51 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MKLM6_RS10650 33f1d03aa6e08d04c5201419cb9a3405 467 PRINTS PR00834 HtrA/DegQ protease family signature 194 211 2.9E-51 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MKLM6_RS10650 33f1d03aa6e08d04c5201419cb9a3405 467 PRINTS PR00834 HtrA/DegQ protease family signature 216 233 2.9E-51 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MKLM6_RS10650 33f1d03aa6e08d04c5201419cb9a3405 467 PRINTS PR00834 HtrA/DegQ protease family signature 99 111 2.9E-51 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MKLM6_RS10650 33f1d03aa6e08d04c5201419cb9a3405 467 PRINTS PR00834 HtrA/DegQ protease family signature 160 184 2.9E-51 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MKLM6_RS10650 33f1d03aa6e08d04c5201419cb9a3405 467 Gene3D G3DSA:2.30.42.10 372 467 1.2E-15 T 28-03-2018 MKLM6_RS10650 33f1d03aa6e08d04c5201419cb9a3405 467 Gene3D G3DSA:2.30.42.10 263 365 9.5E-25 T 28-03-2018 MKLM6_RS10650 33f1d03aa6e08d04c5201419cb9a3405 467 SMART SM00228 376 456 1.2E-6 T 28-03-2018 IPR001478 PDZ domain GO:0005515 MKLM6_RS10650 33f1d03aa6e08d04c5201419cb9a3405 467 SMART SM00228 262 344 1.6E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 MKLM6_RS10650 33f1d03aa6e08d04c5201419cb9a3405 467 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 24 462 2.0E-154 T 28-03-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 MKLM6_RS10650 33f1d03aa6e08d04c5201419cb9a3405 467 Pfam PF13365 Trypsin-like peptidase domain 90 223 2.1E-33 T 28-03-2018 MKLM6_RS10650 33f1d03aa6e08d04c5201419cb9a3405 467 Gene3D G3DSA:2.40.10.10 21 160 1.6E-35 T 28-03-2018 MKLM6_RS10650 33f1d03aa6e08d04c5201419cb9a3405 467 SUPERFAMILY SSF50494 7 44 7.97E-66 T 28-03-2018 IPR009003 Peptidase S1, PA clan MKLM6_RS10650 33f1d03aa6e08d04c5201419cb9a3405 467 SUPERFAMILY SSF50494 87 272 7.97E-66 T 28-03-2018 IPR009003 Peptidase S1, PA clan MKLM6_RS11820 8f20d807dcdcffb77c1396d4c21c8898 313 Pfam PF08349 Protein of unknown function (DUF1722) 188 304 1.4E-39 T 28-03-2018 IPR013560 Domain of unknown function DUF1722 MKLM6_RS11820 8f20d807dcdcffb77c1396d4c21c8898 313 Pfam PF04463 Protein of unknown function (DUF523) 6 145 7.5E-35 T 28-03-2018 IPR007553 Domain of unknown function DUF523 MKLM6_RS11820 8f20d807dcdcffb77c1396d4c21c8898 313 PIRSF PIRSF037004 1 313 5.7E-116 T 28-03-2018 IPR017087 Uncharacterised conserved protein UCP037004 MKLM6_RS07670 14b8e5fb666f0180af73c7d81fc3ecd2 434 Gene3D G3DSA:3.40.50.300 116 370 4.9E-23 T 28-03-2018 MKLM6_RS07670 14b8e5fb666f0180af73c7d81fc3ecd2 434 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 128 264 4.0E-8 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain MKLM6_RS07670 14b8e5fb666f0180af73c7d81fc3ecd2 434 SUPERFAMILY SSF52540 126 320 5.31E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS19275 b801c0ec60fd7fba587be03b80c2e3e1 859 Hamap MF_01871 UPF0753 protein . 32 843 24.085 T 28-03-2018 IPR018752 Uncharacterised protein family UPF0753 MKLM6_RS19275 b801c0ec60fd7fba587be03b80c2e3e1 859 Pfam PF10070 Uncharacterized protein conserved in bacteria (DUF2309) 37 828 7.7E-263 T 28-03-2018 IPR018752 Uncharacterised protein family UPF0753 MKLM6_RS18250 a587f0412a1218ff36922bb1223ec0a7 103 Gene3D G3DSA:1.10.1660.10 11 101 1.7E-8 T 28-03-2018 MKLM6_RS18250 a587f0412a1218ff36922bb1223ec0a7 103 Pfam PF13591 MerR HTH family regulatory protein 19 99 4.9E-9 T 28-03-2018 MKLM6_RS18250 a587f0412a1218ff36922bb1223ec0a7 103 SUPERFAMILY SSF46955 19 67 9.16E-5 T 28-03-2018 IPR009061 Putative DNA-binding domain MKLM6_RS09770 229c5c0d80a10fe2ec07cf95a51810ce 161 Gene3D G3DSA:3.40.630.30 5 151 3.4E-16 T 28-03-2018 MKLM6_RS09770 229c5c0d80a10fe2ec07cf95a51810ce 161 SUPERFAMILY SSF55729 14 147 8.23E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS09770 229c5c0d80a10fe2ec07cf95a51810ce 161 Pfam PF00583 Acetyltransferase (GNAT) family 53 145 2.1E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 MKLM6_RS00350 348e888685593a46c5ddf5b83154a07f 371 SUPERFAMILY SSF56672 5 238 2.13E-86 T 28-03-2018 MKLM6_RS00350 348e888685593a46c5ddf5b83154a07f 371 Gene3D G3DSA:3.30.1490.100 247 361 4.6E-24 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MKLM6_RS00350 348e888685593a46c5ddf5b83154a07f 371 SUPERFAMILY SSF100879 245 349 5.1E-22 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MKLM6_RS00350 348e888685593a46c5ddf5b83154a07f 371 Hamap MF_01113 DNA polymerase IV [dinB]. 5 359 37.081 T 28-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 MKLM6_RS00350 348e888685593a46c5ddf5b83154a07f 371 Pfam PF11799 impB/mucB/samB family C-terminal domain 237 348 3.9E-15 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MKLM6_RS00350 348e888685593a46c5ddf5b83154a07f 371 Pfam PF00817 impB/mucB/samB family 11 158 2.8E-50 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MKLM6_RS00350 348e888685593a46c5ddf5b83154a07f 371 Gene3D G3DSA:1.10.150.20 175 246 1.0E-17 T 28-03-2018 MKLM6_RS00350 348e888685593a46c5ddf5b83154a07f 371 Gene3D G3DSA:3.30.70.270 45 116 3.3E-25 T 28-03-2018 MKLM6_RS00350 348e888685593a46c5ddf5b83154a07f 371 Gene3D G3DSA:3.30.70.270 117 174 6.4E-16 T 28-03-2018 MKLM6_RS19370 44d4a21efb984bacc1ea312508989955 310 SUPERFAMILY SSF53613 2 297 4.68E-61 T 28-03-2018 IPR029056 Ribokinase-like MKLM6_RS19370 44d4a21efb984bacc1ea312508989955 310 Gene3D G3DSA:3.40.1190.20 1 308 2.0E-45 T 28-03-2018 IPR029056 Ribokinase-like MKLM6_RS19370 44d4a21efb984bacc1ea312508989955 310 Pfam PF00294 pfkB family carbohydrate kinase 35 290 8.9E-37 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB MKLM6_RS13615 e60ddb665046503a7876105d360722d8 299 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 4 297 2.3E-113 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MKLM6_RS13615 e60ddb665046503a7876105d360722d8 299 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 4 142 7.1E-48 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 MKLM6_RS13615 e60ddb665046503a7876105d360722d8 299 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 47 54 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MKLM6_RS13615 e60ddb665046503a7876105d360722d8 299 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 3 298 77.625 T 28-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 MKLM6_RS13615 e60ddb665046503a7876105d360722d8 299 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 149 295 1.4E-50 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 MKLM6_RS13615 e60ddb665046503a7876105d360722d8 299 PRINTS PR00102 Ornithine carbamoyltransferase signature 78 91 3.3E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MKLM6_RS13615 e60ddb665046503a7876105d360722d8 299 PRINTS PR00102 Ornithine carbamoyltransferase signature 214 224 3.3E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MKLM6_RS13615 e60ddb665046503a7876105d360722d8 299 PRINTS PR00102 Ornithine carbamoyltransferase signature 118 132 3.3E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MKLM6_RS13615 e60ddb665046503a7876105d360722d8 299 PRINTS PR00102 Ornithine carbamoyltransferase signature 45 59 3.3E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MKLM6_RS13615 e60ddb665046503a7876105d360722d8 299 PRINTS PR00102 Ornithine carbamoyltransferase signature 276 287 3.3E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MKLM6_RS13615 e60ddb665046503a7876105d360722d8 299 Gene3D G3DSA:3.40.50.1370 159 299 2.2E-50 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MKLM6_RS13615 e60ddb665046503a7876105d360722d8 299 SUPERFAMILY SSF53671 2 297 5.5E-103 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MKLM6_RS13615 e60ddb665046503a7876105d360722d8 299 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 262 285 5.5E-27 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MKLM6_RS13615 e60ddb665046503a7876105d360722d8 299 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 129 140 5.5E-27 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MKLM6_RS13615 e60ddb665046503a7876105d360722d8 299 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 47 66 5.5E-27 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MKLM6_RS13615 e60ddb665046503a7876105d360722d8 299 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 250 259 5.5E-27 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MKLM6_RS13615 e60ddb665046503a7876105d360722d8 299 Gene3D G3DSA:3.40.50.1370 2 158 3.1E-60 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MKLM6_RS18535 e5bc3165e4992b327a1c78ed0f2572e5 185 Pfam PF01195 Peptidyl-tRNA hydrolase 4 174 1.0E-50 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MKLM6_RS18535 e5bc3165e4992b327a1c78ed0f2572e5 185 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 15 28 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 MKLM6_RS18535 e5bc3165e4992b327a1c78ed0f2572e5 185 SUPERFAMILY SSF53178 1 179 1.96E-59 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MKLM6_RS18535 e5bc3165e4992b327a1c78ed0f2572e5 185 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 109 119 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 MKLM6_RS18535 e5bc3165e4992b327a1c78ed0f2572e5 185 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 2 179 33.717 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MKLM6_RS18535 e5bc3165e4992b327a1c78ed0f2572e5 185 Gene3D G3DSA:3.40.50.1470 1 183 8.6E-60 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MKLM6_RS18535 e5bc3165e4992b327a1c78ed0f2572e5 185 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 2 171 5.5E-54 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MKLM6_RS15065 2ab5d6f25f1c6c0337eca8f5329e5975 725 Pfam PF07715 TonB-dependent Receptor Plug Domain 49 159 1.2E-20 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS15065 2ab5d6f25f1c6c0337eca8f5329e5975 725 Gene3D G3DSA:2.170.130.10 27 171 4.9E-24 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS15065 2ab5d6f25f1c6c0337eca8f5329e5975 725 Gene3D G3DSA:2.40.170.20 173 725 6.1E-66 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS15065 2ab5d6f25f1c6c0337eca8f5329e5975 725 SUPERFAMILY SSF56935 30 725 3.26E-106 T 28-03-2018 MKLM6_RS15065 2ab5d6f25f1c6c0337eca8f5329e5975 725 Pfam PF00577 Outer membrane usher protein 181 326 4.1E-4 T 28-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 MKLM6_RS15065 2ab5d6f25f1c6c0337eca8f5329e5975 725 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 708 725 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site MKLM6_RS02425 29c8b2b8c4a7cd42b7e9d8fd6ad01667 108 SUPERFAMILY SSF54913 1 105 1.56E-23 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MKLM6_RS02425 29c8b2b8c4a7cd42b7e9d8fd6ad01667 108 Pfam PF00543 Nitrogen regulatory protein P-II 4 101 2.6E-18 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MKLM6_RS02425 29c8b2b8c4a7cd42b7e9d8fd6ad01667 108 Gene3D G3DSA:3.30.70.120 1 105 2.7E-24 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MKLM6_RS02425 29c8b2b8c4a7cd42b7e9d8fd6ad01667 108 PRINTS PR00340 P-II protein signature 79 99 1.4E-9 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MKLM6_RS02425 29c8b2b8c4a7cd42b7e9d8fd6ad01667 108 PRINTS PR00340 P-II protein signature 2 17 1.4E-9 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MKLM6_RS02425 29c8b2b8c4a7cd42b7e9d8fd6ad01667 108 PRINTS PR00340 P-II protein signature 48 71 1.4E-9 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MKLM6_RS02425 29c8b2b8c4a7cd42b7e9d8fd6ad01667 108 SMART SM00938 4 101 5.3E-25 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MKLM6_RS02350 befcfea8321e7037940c9a9032285b37 287 Pfam PF03755 YicC-like family, N-terminal region 2 153 1.9E-39 T 28-03-2018 IPR013527 YicC-like, N-terminal MKLM6_RS02350 befcfea8321e7037940c9a9032285b37 287 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 287 9.4E-80 T 28-03-2018 IPR005229 Conserved hypothetical protein CHP00255 MKLM6_RS02350 befcfea8321e7037940c9a9032285b37 287 Pfam PF08340 Domain of unknown function (DUF1732) 203 287 1.3E-34 T 28-03-2018 IPR013551 Domain of unknown function DUF1732 MKLM6_RS03180 8e18261399c6fc98d5a53035fc191fdc 151 Pfam PF00692 dUTPase 17 149 9.9E-39 T 28-03-2018 IPR029054 dUTPase-like MKLM6_RS03180 8e18261399c6fc98d5a53035fc191fdc 151 SUPERFAMILY SSF51283 1 150 2.36E-54 T 28-03-2018 IPR029054 dUTPase-like MKLM6_RS03180 8e18261399c6fc98d5a53035fc191fdc 151 Gene3D G3DSA:2.70.40.10 1 112 2.3E-40 T 28-03-2018 MKLM6_RS03180 8e18261399c6fc98d5a53035fc191fdc 151 Gene3D G3DSA:2.70.40.10 113 150 3.8E-14 T 28-03-2018 MKLM6_RS03180 8e18261399c6fc98d5a53035fc191fdc 151 TIGRFAM TIGR00576 dut: dUTP diphosphatase 10 150 2.5E-48 T 28-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 MKLM6_RS03180 8e18261399c6fc98d5a53035fc191fdc 151 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 6 150 33.184 T 28-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 MKLM6_RS08240 d3513032f112228a7b8c2fd43c7b2a57 194 Pfam PF00578 AhpC/TSA family 27 165 7.6E-24 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MKLM6_RS08240 d3513032f112228a7b8c2fd43c7b2a57 194 Gene3D G3DSA:3.40.30.10 13 190 1.6E-26 T 28-03-2018 MKLM6_RS08240 d3513032f112228a7b8c2fd43c7b2a57 194 SUPERFAMILY SSF52833 26 187 1.41E-31 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS07360 0f9d944aa9f98e3801d53c39faf9308b 365 Hamap MF_00569 Quinolinate synthase A [nadA]. 15 364 47.386 T 28-03-2018 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MKLM6_RS07360 0f9d944aa9f98e3801d53c39faf9308b 365 Gene3D G3DSA:3.40.50.10800 226 341 1.3E-20 T 28-03-2018 MKLM6_RS07360 0f9d944aa9f98e3801d53c39faf9308b 365 Gene3D G3DSA:3.40.50.10800 18 114 2.8E-16 T 28-03-2018 MKLM6_RS07360 0f9d944aa9f98e3801d53c39faf9308b 365 Pfam PF02445 Quinolinate synthetase A protein 22 362 7.1E-105 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MKLM6_RS07360 0f9d944aa9f98e3801d53c39faf9308b 365 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 18 362 2.8E-88 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MKLM6_RS07360 0f9d944aa9f98e3801d53c39faf9308b 365 SUPERFAMILY SSF142754 25 362 5.75E-94 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MKLM6_RS07360 0f9d944aa9f98e3801d53c39faf9308b 365 Gene3D G3DSA:3.40.50.10800 115 199 4.8E-25 T 28-03-2018 MKLM6_RS10795 3cdd73597e65d65ec6927afcb293f878 367 SUPERFAMILY SSF53383 17 364 5.71E-81 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS10795 3cdd73597e65d65ec6927afcb293f878 367 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 11 362 1.6E-109 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MKLM6_RS10795 3cdd73597e65d65ec6927afcb293f878 367 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 224 233 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 MKLM6_RS10795 3cdd73597e65d65ec6927afcb293f878 367 Pfam PF00155 Aminotransferase class I and II 35 360 2.6E-53 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MKLM6_RS10795 3cdd73597e65d65ec6927afcb293f878 367 Gene3D G3DSA:3.40.640.10 50 254 4.0E-38 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS10795 3cdd73597e65d65ec6927afcb293f878 367 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 7 364 59.34 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MKLM6_RS10795 3cdd73597e65d65ec6927afcb293f878 367 Gene3D G3DSA:3.90.1150.10 255 363 1.4E-25 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS01055 ccc697c93b046c56b34c3c3d16312771 411 Pfam PF00534 Glycosyl transferases group 1 217 352 2.8E-13 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 MKLM6_RS01055 ccc697c93b046c56b34c3c3d16312771 411 SUPERFAMILY SSF53756 1 306 1.41E-41 T 28-03-2018 MKLM6_RS01055 ccc697c93b046c56b34c3c3d16312771 411 Pfam PF13579 Glycosyl transferase 4-like domain 15 202 3.6E-21 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MKLM6_RS01055 ccc697c93b046c56b34c3c3d16312771 411 Gene3D G3DSA:3.40.50.2000 212 392 2.1E-15 T 28-03-2018 MKLM6_RS01055 ccc697c93b046c56b34c3c3d16312771 411 Gene3D G3DSA:3.40.50.2000 20 211 8.9E-17 T 28-03-2018 MKLM6_RS06090 6d25ee40ef16df6a9da17c67b06efe8f 750 Gene3D G3DSA:3.40.50.1460 498 733 8.7E-39 T 28-03-2018 MKLM6_RS06090 6d25ee40ef16df6a9da17c67b06efe8f 750 SMART SM00671 148 183 5.3E-10 T 28-03-2018 IPR006597 Sel1-like repeat MKLM6_RS06090 6d25ee40ef16df6a9da17c67b06efe8f 750 SMART SM00671 112 147 3.8E-8 T 28-03-2018 IPR006597 Sel1-like repeat MKLM6_RS06090 6d25ee40ef16df6a9da17c67b06efe8f 750 Gene3D G3DSA:2.60.40.1180 86 253 9.2E-27 T 28-03-2018 MKLM6_RS06090 6d25ee40ef16df6a9da17c67b06efe8f 750 Pfam PF00656 Caspase domain 510 731 6.1E-22 T 28-03-2018 MKLM6_RS06090 6d25ee40ef16df6a9da17c67b06efe8f 750 SUPERFAMILY SSF81901 90 198 1.09E-21 T 28-03-2018 MKLM6_RS06090 6d25ee40ef16df6a9da17c67b06efe8f 750 Pfam PF08238 Sel1 repeat 112 147 7.0E-6 T 28-03-2018 IPR006597 Sel1-like repeat MKLM6_RS06090 6d25ee40ef16df6a9da17c67b06efe8f 750 Pfam PF08238 Sel1 repeat 148 179 6.7E-7 T 28-03-2018 IPR006597 Sel1-like repeat MKLM6_RS06090 6d25ee40ef16df6a9da17c67b06efe8f 750 SUPERFAMILY SSF52129 509 732 3.98E-19 T 28-03-2018 IPR029030 Caspase-like domain MKLM6_RS06090 6d25ee40ef16df6a9da17c67b06efe8f 750 Gene3D G3DSA:1.20.120.330 254 385 0.0061 T 28-03-2018 MKLM6_RS14815 9dba3b3ee17d0a3a37d7e0d8c26fed98 346 Gene3D G3DSA:3.30.450.40 189 346 1.0E-41 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS14815 9dba3b3ee17d0a3a37d7e0d8c26fed98 346 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 8 342 5.6E-100 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 MKLM6_RS14815 9dba3b3ee17d0a3a37d7e0d8c26fed98 346 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 6 336 28.197 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 MKLM6_RS14815 9dba3b3ee17d0a3a37d7e0d8c26fed98 346 Gene3D G3DSA:1.10.10.10 2 90 5.4E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS14815 9dba3b3ee17d0a3a37d7e0d8c26fed98 346 SUPERFAMILY SSF46785 6 88 4.73E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS14815 9dba3b3ee17d0a3a37d7e0d8c26fed98 346 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 14 78 1.3E-4 T 28-03-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 MKLM6_RS14815 9dba3b3ee17d0a3a37d7e0d8c26fed98 346 SUPERFAMILY SSF55781 76 344 2.94E-61 T 28-03-2018 IPR029016 GAF domain-like MKLM6_RS14815 9dba3b3ee17d0a3a37d7e0d8c26fed98 346 Pfam PF01628 HrcA protein C terminal domain 110 329 4.6E-60 T 28-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 MKLM6_RS14815 9dba3b3ee17d0a3a37d7e0d8c26fed98 346 PIRSF PIRSF005485 4 346 6.8E-108 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 MKLM6_RS18585 7cab5a2833ddca376c67cc0e892ca7f1 141 Pfam PF14464 Prokaryotic homologs of the JAB domain 14 113 5.2E-16 T 28-03-2018 IPR028090 JAB domain, prokaryotic MKLM6_RS18585 7cab5a2833ddca376c67cc0e892ca7f1 141 SUPERFAMILY SSF102712 7 135 1.31E-23 T 28-03-2018 MKLM6_RS18585 7cab5a2833ddca376c67cc0e892ca7f1 141 Gene3D G3DSA:3.40.140.10 4 141 1.0E-18 T 28-03-2018 MKLM6_RS18585 7cab5a2833ddca376c67cc0e892ca7f1 141 SMART SM00232 6 136 0.0029 T 28-03-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 MKLM6_RS16245 d00076c0a2c026cf453025a425cf607f 602 Pfam PF13360 PQQ-like domain 114 235 2.4E-8 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat MKLM6_RS16245 d00076c0a2c026cf453025a425cf607f 602 Pfam PF01011 PQQ enzyme repeat 508 543 2.8E-6 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat MKLM6_RS16245 d00076c0a2c026cf453025a425cf607f 602 SMART SM00564 452 492 350.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MKLM6_RS16245 d00076c0a2c026cf453025a425cf607f 602 SMART SM00564 191 228 5.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MKLM6_RS16245 d00076c0a2c026cf453025a425cf607f 602 SMART SM00564 502 533 5.0E-5 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MKLM6_RS16245 d00076c0a2c026cf453025a425cf607f 602 SMART SM00564 87 120 43.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MKLM6_RS16245 d00076c0a2c026cf453025a425cf607f 602 SMART SM00564 144 177 9.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MKLM6_RS16245 d00076c0a2c026cf453025a425cf607f 602 SMART SM00564 344 378 330.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MKLM6_RS16245 d00076c0a2c026cf453025a425cf607f 602 Gene3D G3DSA:2.140.10.10 30 602 4.4E-107 T 28-03-2018 MKLM6_RS16245 d00076c0a2c026cf453025a425cf607f 602 SUPERFAMILY SSF50998 37 600 8.11E-164 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MKLM6_RS16245 d00076c0a2c026cf453025a425cf607f 602 TIGRFAM TIGR03075 PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family 26 561 1.4E-204 T 28-03-2018 IPR017512 PQQ-dependent dehydrogenase, methanol/ethanol family GO:0005509|GO:0016020|GO:0016614|GO:0055114 MKLM6_RS13710 36fa67b205a6df138ec8e9e821d9f601 302 Pfam PF09991 Predicted membrane protein (DUF2232) 19 289 2.3E-7 T 28-03-2018 IPR018710 Protein of unknown function DUF2232 MKLM6_RS18360 4468e27391a7136cc046c874274ecdd2 117 Gene3D G3DSA:3.30.420.100 1 117 3.4E-33 T 28-03-2018 MKLM6_RS18360 4468e27391a7136cc046c874274ecdd2 117 SUPERFAMILY SSF53137 3 115 1.44E-47 T 28-03-2018 MKLM6_RS18360 4468e27391a7136cc046c874274ecdd2 117 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 117 25.399 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18360 4468e27391a7136cc046c874274ecdd2 117 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 3 117 2.0E-37 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS18360 4468e27391a7136cc046c874274ecdd2 117 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 1 117 5.1E-38 T 28-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS10050 93239a07f01a19d49ac6c6ab2567c09c 126 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 17 119 9.5E-23 T 28-03-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 MKLM6_RS10050 93239a07f01a19d49ac6c6ab2567c09c 126 SUPERFAMILY SSF81343 15 119 6.76E-23 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MKLM6_RS10050 93239a07f01a19d49ac6c6ab2567c09c 126 Gene3D G3DSA:1.20.1300.10 15 123 3.4E-16 T 28-03-2018 MKLM6_RS10050 93239a07f01a19d49ac6c6ab2567c09c 126 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 15 115 5.3E-14 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MKLM6_RS21005 7770ecc7b908003e8822bd1dd0abfbf3 169 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 161 1.9E-17 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS21005 7770ecc7b908003e8822bd1dd0abfbf3 169 Gene3D G3DSA:1.10.1740.10 7 75 5.3E-12 T 28-03-2018 MKLM6_RS21005 7770ecc7b908003e8822bd1dd0abfbf3 169 SUPERFAMILY SSF88659 82 160 3.92E-12 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS21005 7770ecc7b908003e8822bd1dd0abfbf3 169 SUPERFAMILY SSF88946 10 94 6.67E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS21005 7770ecc7b908003e8822bd1dd0abfbf3 169 Gene3D G3DSA:1.10.10.10 76 163 3.2E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS21005 7770ecc7b908003e8822bd1dd0abfbf3 169 Pfam PF04542 Sigma-70 region 2 13 77 4.3E-9 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS21005 7770ecc7b908003e8822bd1dd0abfbf3 169 Pfam PF08281 Sigma-70, region 4 111 155 2.2E-8 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS20500 2b503ad988a1479acff4c8e41ac0eb8b 486 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 480 32.793 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 MKLM6_RS20500 2b503ad988a1479acff4c8e41ac0eb8b 486 Gene3D G3DSA:3.40.1190.10 100 335 8.3E-51 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MKLM6_RS20500 2b503ad988a1479acff4c8e41ac0eb8b 486 Gene3D G3DSA:3.90.190.20 336 486 6.6E-50 T 28-03-2018 MKLM6_RS20500 2b503ad988a1479acff4c8e41ac0eb8b 486 Pfam PF08245 Mur ligase middle domain 109 310 9.7E-48 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MKLM6_RS20500 2b503ad988a1479acff4c8e41ac0eb8b 486 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 17 480 4.5E-153 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 MKLM6_RS20500 2b503ad988a1479acff4c8e41ac0eb8b 486 Pfam PF02875 Mur ligase family, glutamate ligase domain 332 414 3.2E-21 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MKLM6_RS20500 2b503ad988a1479acff4c8e41ac0eb8b 486 Gene3D G3DSA:3.40.1390.10 1 99 8.6E-22 T 28-03-2018 MKLM6_RS20500 2b503ad988a1479acff4c8e41ac0eb8b 486 SUPERFAMILY SSF53623 100 328 2.35E-70 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MKLM6_RS20500 2b503ad988a1479acff4c8e41ac0eb8b 486 SUPERFAMILY SSF63418 1 98 5.49E-20 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MKLM6_RS20500 2b503ad988a1479acff4c8e41ac0eb8b 486 SUPERFAMILY SSF53244 331 483 1.01E-48 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MKLM6_RS20500 2b503ad988a1479acff4c8e41ac0eb8b 486 Pfam PF01225 Mur ligase family, catalytic domain 19 97 3.8E-9 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MKLM6_RS06675 758d9878079cde588686ea7f4a98b0ad 346 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 54 198 1.3E-8 T 28-03-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 MKLM6_RS06675 758d9878079cde588686ea7f4a98b0ad 346 Gene3D G3DSA:3.40.630.10 37 313 9.8E-11 T 28-03-2018 MKLM6_RS06675 758d9878079cde588686ea7f4a98b0ad 346 SUPERFAMILY SSF53187 30 283 1.02E-37 T 28-03-2018 MKLM6_RS15945 93e8302e518b6d4ef69266ea30d7f8cb 293 Hamap MF_00361 NAD kinase [nadK]. 6 288 33.186 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MKLM6_RS15945 93e8302e518b6d4ef69266ea30d7f8cb 293 Gene3D G3DSA:2.60.200.30 142 265 9.6E-38 T 28-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MKLM6_RS15945 93e8302e518b6d4ef69266ea30d7f8cb 293 Gene3D G3DSA:3.40.50.10330 1 141 4.1E-40 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 MKLM6_RS15945 93e8302e518b6d4ef69266ea30d7f8cb 293 SUPERFAMILY SSF111331 7 289 2.22E-87 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain MKLM6_RS15945 93e8302e518b6d4ef69266ea30d7f8cb 293 Pfam PF01513 ATP-NAD kinase 7 270 8.3E-64 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MKLM6_RS00520 c07deb373f3a37272152bf86c9a3cf44 172 Pfam PF06114 IrrE N-terminal-like domain 66 163 4.7E-20 T 28-03-2018 IPR010359 IrrE N-terminal-like domain MKLM6_RS00520 c07deb373f3a37272152bf86c9a3cf44 172 SUPERFAMILY SSF55486 67 123 7.89E-5 T 28-03-2018 MKLM6_RS16110 5e8620adfe0089d851c44f0666efdc5c 71 Pfam PF11146 Protein of unknown function (DUF2905) 4 68 7.6E-19 T 28-03-2018 IPR021320 Protein of unknown function DUF2905 MKLM6_RS13825 8084971ad69c5b5cdfdd8eac3ec205e5 554 Gene3D G3DSA:3.40.50.300 286 551 8.1E-57 T 28-03-2018 MKLM6_RS13825 8084971ad69c5b5cdfdd8eac3ec205e5 554 SUPERFAMILY SSF52540 12 236 9.94E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS13825 8084971ad69c5b5cdfdd8eac3ec205e5 554 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS13825 8084971ad69c5b5cdfdd8eac3ec205e5 554 Pfam PF12848 ABC transporter 230 306 1.4E-12 T 28-03-2018 IPR032781 ABC-transporter extension domain MKLM6_RS13825 8084971ad69c5b5cdfdd8eac3ec205e5 554 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 2 553 2.0E-304 T 28-03-2018 IPR022374 ABC transporter, ATP-binding protein, ChvD MKLM6_RS13825 8084971ad69c5b5cdfdd8eac3ec205e5 554 Gene3D G3DSA:3.40.50.300 1 285 4.5E-53 T 28-03-2018 MKLM6_RS13825 8084971ad69c5b5cdfdd8eac3ec205e5 554 SMART SM00382 348 524 7.8E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS13825 8084971ad69c5b5cdfdd8eac3ec205e5 554 SMART SM00382 31 252 1.4E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS13825 8084971ad69c5b5cdfdd8eac3ec205e5 554 Pfam PF00005 ABC transporter 22 191 7.7E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS13825 8084971ad69c5b5cdfdd8eac3ec205e5 554 Pfam PF00005 ABC transporter 340 473 3.7E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS13825 8084971ad69c5b5cdfdd8eac3ec205e5 554 SUPERFAMILY SSF52540 302 530 2.49E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS01125 8655d0ff9e73cfc68cfa78df16ab36e6 360 PIRSF PIRSF001455 7 356 3.4E-108 T 28-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MKLM6_RS01125 8655d0ff9e73cfc68cfa78df16ab36e6 360 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 14 347 9.3E-114 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MKLM6_RS01125 8655d0ff9e73cfc68cfa78df16ab36e6 360 Gene3D G3DSA:3.40.50.1970 5 171 1.5E-52 T 28-03-2018 MKLM6_RS01125 8655d0ff9e73cfc68cfa78df16ab36e6 360 Pfam PF01761 3-dehydroquinate synthase 67 324 8.6E-106 T 28-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MKLM6_RS01125 8655d0ff9e73cfc68cfa78df16ab36e6 360 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 357 41.393 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MKLM6_RS01125 8655d0ff9e73cfc68cfa78df16ab36e6 360 Gene3D G3DSA:1.20.1090.10 172 359 2.6E-66 T 28-03-2018 MKLM6_RS01125 8655d0ff9e73cfc68cfa78df16ab36e6 360 SUPERFAMILY SSF56796 11 355 3.01E-113 T 28-03-2018 MKLM6_RS18795 b15044480dfba733cbf8f83cef8e1a95 441 Pfam PF07559 Flagellar basal body protein FlaE 184 321 3.1E-22 T 28-03-2018 IPR011491 Flagellar hook protein FlgE MKLM6_RS18795 b15044480dfba733cbf8f83cef8e1a95 441 Pfam PF00460 Flagella basal body rod protein 4 33 2.9E-10 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 MKLM6_RS18795 b15044480dfba733cbf8f83cef8e1a95 441 Gene3D G3DSA:2.60.98.20 157 322 1.1E-27 T 28-03-2018 IPR011491 Flagellar hook protein FlgE MKLM6_RS18795 b15044480dfba733cbf8f83cef8e1a95 441 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 9 29 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site MKLM6_RS18795 b15044480dfba733cbf8f83cef8e1a95 441 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 423 5.5E-97 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G MKLM6_RS18795 b15044480dfba733cbf8f83cef8e1a95 441 SUPERFAMILY SSF117143 79 402 1.57E-70 T 28-03-2018 MKLM6_RS18795 b15044480dfba733cbf8f83cef8e1a95 441 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 362 440 1.2E-17 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain MKLM6_RS01510 dbf9521a2089b42370550d8c10b276b0 156 Gene3D G3DSA:2.60.120.260 31 149 1.8E-9 T 28-03-2018 IPR008979 Galactose-binding domain-like MKLM6_RS01510 dbf9521a2089b42370550d8c10b276b0 156 SUPERFAMILY SSF49785 41 149 2.41E-7 T 28-03-2018 IPR008979 Galactose-binding domain-like MKLM6_RS01220 c0b30d00888567564716f2eee643e10b 111 Pfam PF09919 Uncharacterized conserved protein (DUF2149) 21 111 4.1E-32 T 28-03-2018 IPR018676 Protein of unknown function DUF2149 MKLM6_RS04615 9d4844f7a36872992393d1c0ee80cdbb 176 Gene3D G3DSA:3.40.50.360 3 176 1.3E-35 T 28-03-2018 IPR029039 Flavoprotein-like domain MKLM6_RS04615 9d4844f7a36872992393d1c0ee80cdbb 176 SUPERFAMILY SSF52218 1 173 1.05E-43 T 28-03-2018 IPR029039 Flavoprotein-like domain MKLM6_RS04615 9d4844f7a36872992393d1c0ee80cdbb 176 Pfam PF00258 Flavodoxin 6 167 4.6E-29 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MKLM6_RS04615 9d4844f7a36872992393d1c0ee80cdbb 176 PRINTS PR00369 Flavodoxin signature 5 18 1.9E-6 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MKLM6_RS04615 9d4844f7a36872992393d1c0ee80cdbb 176 PRINTS PR00369 Flavodoxin signature 51 62 1.9E-6 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MKLM6_RS04615 9d4844f7a36872992393d1c0ee80cdbb 176 PRINTS PR00369 Flavodoxin signature 88 98 1.9E-6 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MKLM6_RS04615 9d4844f7a36872992393d1c0ee80cdbb 176 PIRSF PIRSF038996 1 176 6.3E-59 T 28-03-2018 IPR010086 Flavodoxin, long chain GO:0010181 MKLM6_RS04615 9d4844f7a36872992393d1c0ee80cdbb 176 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 28-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 MKLM6_RS04615 9d4844f7a36872992393d1c0ee80cdbb 176 TIGRFAM TIGR01752 flav_long: flavodoxin 3 173 1.3E-61 T 28-03-2018 IPR010086 Flavodoxin, long chain GO:0010181 MKLM6_RS12640 772539dfd31b7a1256a9395c26a81c13 269 SUPERFAMILY SSF110997 192 265 2.22E-16 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 MKLM6_RS12640 772539dfd31b7a1256a9395c26a81c13 269 Pfam PF05036 Sporulation related domain 194 265 1.9E-15 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 MKLM6_RS12640 772539dfd31b7a1256a9395c26a81c13 269 Gene3D G3DSA:3.30.70.1070 195 269 2.2E-16 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 MKLM6_RS21700 4babe6e1d7fe14644c2ac45a22e94c1e 354 SUPERFAMILY SSF111369 59 272 4.97E-22 T 28-03-2018 MKLM6_RS21700 4babe6e1d7fe14644c2ac45a22e94c1e 354 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 57 267 8.5E-25 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MKLM6_RS21700 4babe6e1d7fe14644c2ac45a22e94c1e 354 Gene3D G3DSA:2.40.50.100 157 348 3.1E-9 T 28-03-2018 MKLM6_RS21700 4babe6e1d7fe14644c2ac45a22e94c1e 354 Gene3D G3DSA:2.40.50.100 57 108 7.7E-13 T 28-03-2018 MKLM6_RS21700 4babe6e1d7fe14644c2ac45a22e94c1e 354 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 29 348 7.2E-73 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MKLM6_RS21700 4babe6e1d7fe14644c2ac45a22e94c1e 354 Gene3D G3DSA:1.10.287.470 109 151 8.8E-12 T 28-03-2018 MKLM6_RS17330 2c1f0bf43588f160bf7b9d580221bab2 139 Gene3D G3DSA:3.10.129.10 3 130 2.1E-25 T 28-03-2018 MKLM6_RS17330 2c1f0bf43588f160bf7b9d580221bab2 139 Pfam PF13279 Thioesterase-like superfamily 15 127 8.8E-11 T 28-03-2018 MKLM6_RS17330 2c1f0bf43588f160bf7b9d580221bab2 139 SUPERFAMILY SSF54637 8 125 1.5E-30 T 28-03-2018 IPR029069 HotDog domain MKLM6_RS16145 1c04078a2d66fc7b394d83e936bff2a2 176 SUPERFAMILY SSF52833 26 173 3.46E-44 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS16145 1c04078a2d66fc7b394d83e936bff2a2 176 PIRSF PIRSF000239 21 174 1.2E-23 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MKLM6_RS16145 1c04078a2d66fc7b394d83e936bff2a2 176 Gene3D G3DSA:3.40.30.10 17 172 5.6E-38 T 28-03-2018 MKLM6_RS16145 1c04078a2d66fc7b394d83e936bff2a2 176 Pfam PF00578 AhpC/TSA family 28 151 1.0E-33 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MKLM6_RS12275 e2db6454199a2580df66c9ea8c5be332 63 Pfam PF03621 MbtH-like protein 3 49 2.3E-21 T 28-03-2018 IPR005153 MbtH-like protein MKLM6_RS12275 e2db6454199a2580df66c9ea8c5be332 63 SUPERFAMILY SSF160582 4 61 4.45E-24 T 28-03-2018 MKLM6_RS12275 e2db6454199a2580df66c9ea8c5be332 63 Gene3D G3DSA:3.90.820.10 1 63 3.0E-27 T 28-03-2018 MKLM6_RS12275 e2db6454199a2580df66c9ea8c5be332 63 SMART SM00923 1 50 6.6E-19 T 28-03-2018 IPR005153 MbtH-like protein MKLM6_RS09540 767d5cc5cf24e4a81163dbacf4715a69 60 SUPERFAMILY SSF69047 1 59 1.07E-17 T 28-03-2018 IPR008462 CsbD-like domain MKLM6_RS09540 767d5cc5cf24e4a81163dbacf4715a69 60 Gene3D G3DSA:1.10.1470.10 1 60 8.5E-18 T 28-03-2018 IPR008462 CsbD-like domain MKLM6_RS09540 767d5cc5cf24e4a81163dbacf4715a69 60 Pfam PF05532 CsbD-like 4 56 1.1E-17 T 28-03-2018 IPR008462 CsbD-like domain MKLM6_RS11305 f51d1bd59f03c7b4b6aaa3886bd8b19e 416 Pfam PF03471 Transporter associated domain 340 415 5.9E-16 T 28-03-2018 IPR005170 Transporter-associated domain MKLM6_RS11305 f51d1bd59f03c7b4b6aaa3886bd8b19e 416 SUPERFAMILY SSF56176 335 415 1.15E-20 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MKLM6_RS11305 f51d1bd59f03c7b4b6aaa3886bd8b19e 416 SMART SM00116 215 264 6.9 T 28-03-2018 IPR000644 CBS domain MKLM6_RS11305 f51d1bd59f03c7b4b6aaa3886bd8b19e 416 SMART SM00116 279 327 1.7 T 28-03-2018 IPR000644 CBS domain MKLM6_RS11305 f51d1bd59f03c7b4b6aaa3886bd8b19e 416 Pfam PF01595 Domain of unknown function DUF21 13 186 3.8E-45 T 28-03-2018 IPR002550 Domain of unknown function DUF21 MKLM6_RS11305 f51d1bd59f03c7b4b6aaa3886bd8b19e 416 SMART SM01091 338 416 1.1E-23 T 28-03-2018 IPR005170 Transporter-associated domain MKLM6_RS11305 f51d1bd59f03c7b4b6aaa3886bd8b19e 416 Gene3D G3DSA:3.20.20.70 144 344 2.8E-30 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS11305 f51d1bd59f03c7b4b6aaa3886bd8b19e 416 Pfam PF00571 CBS domain 206 264 5.3E-5 T 28-03-2018 IPR000644 CBS domain MKLM6_RS11305 f51d1bd59f03c7b4b6aaa3886bd8b19e 416 Pfam PF00571 CBS domain 279 327 3.1E-7 T 28-03-2018 IPR000644 CBS domain MKLM6_RS11305 f51d1bd59f03c7b4b6aaa3886bd8b19e 416 SUPERFAMILY SSF54631 194 329 4.15E-27 T 28-03-2018 MKLM6_RS11305 f51d1bd59f03c7b4b6aaa3886bd8b19e 416 Gene3D G3DSA:3.30.465.10 345 416 7.2E-19 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MKLM6_RS11210 45e9dd05ecd38e8dbddfdd27b066a2be 179 Pfam PF00872 Transposase, Mutator family 100 165 1.1E-8 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS06520 e086e973b3816d360fce8d79ed99140c 160 SUPERFAMILY SSF75169 33 144 2.35E-10 T 28-03-2018 IPR027396 DsrEFH-like MKLM6_RS06520 e086e973b3816d360fce8d79ed99140c 160 Pfam PF02635 DsrE/DsrF-like family 53 134 2.3E-4 T 28-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein MKLM6_RS06520 e086e973b3816d360fce8d79ed99140c 160 TIGRFAM TIGR04044 MSMEG_0572_fam: MSMEG_0572 family protein 2 160 1.2E-83 T 28-03-2018 IPR023847 Conserved hypothetical protein CHP04044, MSMEG0572 MKLM6_RS06520 e086e973b3816d360fce8d79ed99140c 160 Gene3D G3DSA:3.40.1260.10 27 153 2.6E-11 T 28-03-2018 MKLM6_RS10350 b61db0272d21952f8acc11848628323e 507 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 41 54 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 MKLM6_RS10350 b61db0272d21952f8acc11848628323e 507 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 3 501 6.9E-245 T 28-03-2018 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 MKLM6_RS10350 b61db0272d21952f8acc11848628323e 507 Gene3D G3DSA:3.40.1020.10 327 503 5.1E-66 T 28-03-2018 MKLM6_RS10350 b61db0272d21952f8acc11848628323e 507 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 318 408 2.9E-20 T 28-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 MKLM6_RS10350 b61db0272d21952f8acc11848628323e 507 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 421 501 1.1E-20 T 28-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 MKLM6_RS10350 b61db0272d21952f8acc11848628323e 507 Gene3D G3DSA:3.40.50.1100 26 136 2.8E-35 T 28-03-2018 MKLM6_RS10350 b61db0272d21952f8acc11848628323e 507 SUPERFAMILY SSF55021 409 501 6.41E-23 T 28-03-2018 MKLM6_RS10350 b61db0272d21952f8acc11848628323e 507 SUPERFAMILY SSF55021 326 412 7.55E-25 T 28-03-2018 MKLM6_RS10350 b61db0272d21952f8acc11848628323e 507 Gene3D G3DSA:3.40.50.1100 137 312 4.2E-52 T 28-03-2018 MKLM6_RS10350 b61db0272d21952f8acc11848628323e 507 SUPERFAMILY SSF53686 4 354 4.32E-107 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MKLM6_RS10350 b61db0272d21952f8acc11848628323e 507 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 16 304 2.2E-85 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MKLM6_RS12945 d41339426f0d56c2fc15c98d1014204c 411 Pfam PF12872 OST-HTH/LOTUS domain 194 252 9.2E-8 T 28-03-2018 IPR025605 OST-HTH/LOTUS domain MKLM6_RS12945 d41339426f0d56c2fc15c98d1014204c 411 Pfam PF01936 NYN domain 6 145 3.6E-24 T 28-03-2018 IPR021139 NYN domain, limkain-b1-type MKLM6_RS12945 d41339426f0d56c2fc15c98d1014204c 411 Gene3D G3DSA:3.40.50.1010 2 150 1.7E-22 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS09010 06e6055de6a786dd44a3470eaf76a0a5 445 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 81 442 3.8E-146 T 28-03-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain MKLM6_RS09010 06e6055de6a786dd44a3470eaf76a0a5 445 SUPERFAMILY SSF52440 234 340 3.16E-34 T 28-03-2018 IPR016185 Pre-ATP-grasp domain MKLM6_RS09010 06e6055de6a786dd44a3470eaf76a0a5 445 SUPERFAMILY SSF56059 71 230 7.06E-82 T 28-03-2018 MKLM6_RS09010 06e6055de6a786dd44a3470eaf76a0a5 445 SUPERFAMILY SSF56059 327 441 7.06E-82 T 28-03-2018 MKLM6_RS11445 1b1e8591d6013c2d51194d9de98b2c8f 256 SUPERFAMILY SSF56281 11 238 6.55E-34 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS11445 1b1e8591d6013c2d51194d9de98b2c8f 256 Gene3D G3DSA:3.60.15.10 8 244 2.0E-27 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS11445 1b1e8591d6013c2d51194d9de98b2c8f 256 Pfam PF00753 Metallo-beta-lactamase superfamily 30 220 9.4E-19 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS11445 1b1e8591d6013c2d51194d9de98b2c8f 256 SMART SM00849 29 220 1.1E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS15240 d9f6c81db9d6f91c46b44bcfa624a8ab 331 SUPERFAMILY SSF111369 151 261 3.79E-6 T 28-03-2018 MKLM6_RS15240 d9f6c81db9d6f91c46b44bcfa624a8ab 331 Gene3D G3DSA:1.20.1600.10 31 298 3.4E-19 T 28-03-2018 MKLM6_RS15240 d9f6c81db9d6f91c46b44bcfa624a8ab 331 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 42 291 3.0E-8 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MKLM6_RS08145 85feca9c8df4d167fa2ca0bedcedc593 218 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 10 197 5.5E-78 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 MKLM6_RS08145 85feca9c8df4d167fa2ca0bedcedc593 218 SUPERFAMILY SSF142695 6 175 1.57E-65 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 MKLM6_RS08145 85feca9c8df4d167fa2ca0bedcedc593 218 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 4 199 40.47 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 MKLM6_RS08145 85feca9c8df4d167fa2ca0bedcedc593 218 Pfam PF00925 GTP cyclohydrolase II 10 173 1.0E-71 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 MKLM6_RS03090 e2245071c6c14cb0f0f1c1d192eb2005 468 PIRSF PIRSF006446 2 467 1.2E-78 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MKLM6_RS03090 e2245071c6c14cb0f0f1c1d192eb2005 468 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 9 454 4.3E-95 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MKLM6_RS20790 7bc291eeacae8fb22028ec9b8f7310b9 212 Gene3D G3DSA:3.40.50.2020 3 212 1.7E-45 T 28-03-2018 MKLM6_RS20790 7bc291eeacae8fb22028ec9b8f7310b9 212 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 11 186 6.8E-59 T 28-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MKLM6_RS20790 7bc291eeacae8fb22028ec9b8f7310b9 212 Pfam PF00156 Phosphoribosyl transferase domain 45 162 2.6E-9 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MKLM6_RS20790 7bc291eeacae8fb22028ec9b8f7310b9 212 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 212 33.534 T 28-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MKLM6_RS20790 7bc291eeacae8fb22028ec9b8f7310b9 212 SUPERFAMILY SSF53271 3 211 5.11E-46 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like MKLM6_RS17065 e53c3317fd4f406443ab7a02ac3c7362 633 PRINTS PR00811 Bacterial general secretion pathway protein D signature 543 561 2.5E-12 T 28-03-2018 IPR001775 GspD/PilQ family MKLM6_RS17065 e53c3317fd4f406443ab7a02ac3c7362 633 PRINTS PR00811 Bacterial general secretion pathway protein D signature 331 341 2.5E-12 T 28-03-2018 IPR001775 GspD/PilQ family MKLM6_RS17065 e53c3317fd4f406443ab7a02ac3c7362 633 PRINTS PR00811 Bacterial general secretion pathway protein D signature 393 417 2.5E-12 T 28-03-2018 IPR001775 GspD/PilQ family MKLM6_RS17065 e53c3317fd4f406443ab7a02ac3c7362 633 PRINTS PR00811 Bacterial general secretion pathway protein D signature 566 580 2.5E-12 T 28-03-2018 IPR001775 GspD/PilQ family MKLM6_RS17065 e53c3317fd4f406443ab7a02ac3c7362 633 Pfam PF00263 Bacterial type II and III secretion system protein 398 578 6.0E-39 T 28-03-2018 IPR004846 Type II/III secretion system GO:0009306 MKLM6_RS00145 824d041e14033698132c0ffdc58136b8 157 Gene3D G3DSA:3.40.140.10 33 157 3.7E-44 T 28-03-2018 MKLM6_RS00145 824d041e14033698132c0ffdc58136b8 157 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 107 112 - T 28-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site MKLM6_RS00145 824d041e14033698132c0ffdc58136b8 157 TIGRFAM TIGR00608 radc: DNA repair protein RadC 34 157 6.4E-42 T 28-03-2018 IPR001405 RadC protein MKLM6_RS00145 824d041e14033698132c0ffdc58136b8 157 Pfam PF04002 RadC-like JAB domain 38 156 6.2E-44 T 28-03-2018 IPR025657 RadC-like JAB domain MKLM6_RS06910 f30fe08328a5b5297c65b44938a581d5 663 SMART SM00283 401 662 2.8E-75 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS06910 f30fe08328a5b5297c65b44938a581d5 663 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 447 629 5.0E-41 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS06910 f30fe08328a5b5297c65b44938a581d5 663 SMART SM00304 334 386 0.0084 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS06910 f30fe08328a5b5297c65b44938a581d5 663 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 126 9.9E-9 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain MKLM6_RS06910 f30fe08328a5b5297c65b44938a581d5 663 Gene3D G3DSA:1.10.287.950 442 663 2.2E-49 T 28-03-2018 MKLM6_RS06910 f30fe08328a5b5297c65b44938a581d5 663 SUPERFAMILY SSF58104 354 663 1.01E-74 T 28-03-2018 MKLM6_RS06910 f30fe08328a5b5297c65b44938a581d5 663 Gene3D G3DSA:1.10.287.850 364 441 6.2E-4 T 28-03-2018 MKLM6_RS06475 a075cf5f0d11125b6a4316a355c46467 669 SUPERFAMILY SSF56935 46 669 3.55E-91 T 28-03-2018 MKLM6_RS06475 a075cf5f0d11125b6a4316a355c46467 669 Pfam PF07715 TonB-dependent Receptor Plug Domain 51 160 1.4E-21 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS06475 a075cf5f0d11125b6a4316a355c46467 669 Pfam PF00593 TonB dependent receptor 232 643 5.1E-27 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS06475 a075cf5f0d11125b6a4316a355c46467 669 Gene3D G3DSA:2.40.170.20 168 669 1.4E-50 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS06475 a075cf5f0d11125b6a4316a355c46467 669 Gene3D G3DSA:2.170.130.10 29 167 1.4E-27 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS07300 7bd6e16f8de7dd8f36bdfe7d6baee5cd 334 Gene3D G3DSA:3.90.1200.10 98 332 2.0E-37 T 28-03-2018 MKLM6_RS07300 7bd6e16f8de7dd8f36bdfe7d6baee5cd 334 Gene3D G3DSA:3.30.200.20 7 97 5.0E-29 T 28-03-2018 MKLM6_RS07300 7bd6e16f8de7dd8f36bdfe7d6baee5cd 334 Pfam PF01636 Phosphotransferase enzyme family 30 251 7.5E-30 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase MKLM6_RS07300 7bd6e16f8de7dd8f36bdfe7d6baee5cd 334 SUPERFAMILY SSF56112 10 312 2.07E-54 T 28-03-2018 IPR011009 Protein kinase-like domain MKLM6_RS10230 f958033fb079ba0994a6bf509d727e32 251 Gene3D G3DSA:3.40.50.150 2 239 7.7E-23 T 28-03-2018 MKLM6_RS10230 f958033fb079ba0994a6bf509d727e32 251 PIRSF PIRSF031679 1 245 5.3E-93 T 28-03-2018 IPR016980 S-adenosyl-L-methionine dependent methyltransferase, Alr7345, predicted MKLM6_RS10230 f958033fb079ba0994a6bf509d727e32 251 SUPERFAMILY SSF53335 24 207 6.24E-14 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS06265 864e040b5eb85e7327dad79b740bf004 229 TIGRFAM TIGR00861 MIP: MIP family channel proteins 6 221 1.7E-58 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 MKLM6_RS06265 864e040b5eb85e7327dad79b740bf004 229 SUPERFAMILY SSF81338 1 224 1.44E-67 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MKLM6_RS06265 864e040b5eb85e7327dad79b740bf004 229 Pfam PF00230 Major intrinsic protein 2 221 3.4E-50 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 MKLM6_RS06265 864e040b5eb85e7327dad79b740bf004 229 PRINTS PR00783 Major intrinsic protein family signature 79 98 7.7E-53 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 MKLM6_RS06265 864e040b5eb85e7327dad79b740bf004 229 PRINTS PR00783 Major intrinsic protein family signature 2 21 7.7E-53 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 MKLM6_RS06265 864e040b5eb85e7327dad79b740bf004 229 PRINTS PR00783 Major intrinsic protein family signature 42 66 7.7E-53 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 MKLM6_RS06265 864e040b5eb85e7327dad79b740bf004 229 PRINTS PR00783 Major intrinsic protein family signature 165 187 7.7E-53 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 MKLM6_RS06265 864e040b5eb85e7327dad79b740bf004 229 PRINTS PR00783 Major intrinsic protein family signature 204 224 7.7E-53 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 MKLM6_RS06265 864e040b5eb85e7327dad79b740bf004 229 PRINTS PR00783 Major intrinsic protein family signature 135 153 7.7E-53 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 MKLM6_RS06265 864e040b5eb85e7327dad79b740bf004 229 Gene3D G3DSA:1.20.1080.10 1 229 2.1E-69 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MKLM6_RS06265 864e040b5eb85e7327dad79b740bf004 229 Hamap MF_01146 Aquaporin Z [aqpZ]. 1 228 35.674 T 28-03-2018 IPR023743 Aquaporin Z GO:0006833|GO:0015250|GO:0016021|GO:0055085 MKLM6_RS06265 864e040b5eb85e7327dad79b740bf004 229 ProSitePatterns PS00221 MIP family signature. 60 68 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 MKLM6_RS17115 faf3d6412f44c9059c73e4a528fc24f4 550 Pfam PF00437 Type II/IV secretion system protein 175 435 3.7E-71 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 MKLM6_RS17115 faf3d6412f44c9059c73e4a528fc24f4 550 SUPERFAMILY SSF160246 13 138 7.06E-15 T 28-03-2018 MKLM6_RS17115 faf3d6412f44c9059c73e4a528fc24f4 550 Gene3D G3DSA:3.30.450.90 134 270 5.8E-32 T 28-03-2018 MKLM6_RS17115 faf3d6412f44c9059c73e4a528fc24f4 550 SUPERFAMILY SSF52540 159 538 2.83E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS17115 faf3d6412f44c9059c73e4a528fc24f4 550 Gene3D G3DSA:3.40.50.300 271 546 6.6E-58 T 28-03-2018 MKLM6_RS17115 faf3d6412f44c9059c73e4a528fc24f4 550 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 50 139 6.1E-13 T 28-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 MKLM6_RS17115 faf3d6412f44c9059c73e4a528fc24f4 550 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 363 377 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 MKLM6_RS07560 e9cd71b013ed597007d616d85904c9cf 332 SUPERFAMILY SSF111369 107 253 5.49E-6 T 28-03-2018 MKLM6_RS07560 e9cd71b013ed597007d616d85904c9cf 332 Gene3D G3DSA:1.10.287.470 104 160 3.0E-6 T 28-03-2018 MKLM6_RS21845 c626598c955b5f515fbc34158b754cb2 990 SUPERFAMILY SSF51998 75 709 7.02E-104 T 28-03-2018 MKLM6_RS21845 c626598c955b5f515fbc34158b754cb2 990 SUPERFAMILY SSF51998 746 975 7.02E-104 T 28-03-2018 MKLM6_RS21845 c626598c955b5f515fbc34158b754cb2 990 Pfam PF02901 Pyruvate formate lyase-like 73 818 3.2E-104 T 28-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 MKLM6_RS21845 c626598c955b5f515fbc34158b754cb2 990 Gene3D G3DSA:3.20.70.20 60 978 5.7E-200 T 28-03-2018 MKLM6_RS09520 5bd8e9e422b4334ef4db9651e95e5671 415 Gene3D G3DSA:1.10.443.10 224 415 3.9E-13 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS09520 5bd8e9e422b4334ef4db9651e95e5671 415 SUPERFAMILY SSF56349 134 353 1.03E-16 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS09520 5bd8e9e422b4334ef4db9651e95e5671 415 Gene3D G3DSA:1.10.150.130 120 223 3.8E-7 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal MKLM6_RS09520 5bd8e9e422b4334ef4db9651e95e5671 415 Pfam PF12835 Integrase 223 351 5.5E-16 T 28-03-2018 IPR024456 Integrase catalytic domain, putative MKLM6_RS04210 fe5b3ca53b40f61418dab87682674d57 715 SUPERFAMILY SSF53098 474 532 1.37E-16 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS04210 fe5b3ca53b40f61418dab87682674d57 715 SUPERFAMILY SSF53098 295 441 1.37E-16 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS04210 fe5b3ca53b40f61418dab87682674d57 715 Pfam PF09299 Mu transposase, C-terminal 544 601 8.2E-8 T 28-03-2018 IPR015378 Transposase-like, Mu, C-terminal MKLM6_RS04210 fe5b3ca53b40f61418dab87682674d57 715 Gene3D G3DSA:1.10.10.10 9 71 4.2E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS04210 fe5b3ca53b40f61418dab87682674d57 715 SUPERFAMILY SSF50610 530 603 1.19E-9 T 28-03-2018 IPR009004 Transposase, Mu, C-terminal MKLM6_RS04210 fe5b3ca53b40f61418dab87682674d57 715 Gene3D G3DSA:2.30.30.130 539 604 7.2E-11 T 28-03-2018 IPR015378 Transposase-like, Mu, C-terminal MKLM6_RS04210 fe5b3ca53b40f61418dab87682674d57 715 Gene3D G3DSA:3.30.420.10 285 538 3.7E-15 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS09875 1afb0a2e82a48f1fe0744f9e4747c9e8 416 TIGRFAM TIGR02564 cas_Csy1: CRISPR type I-F/YPEST-associated protein Csy1 40 400 1.1E-65 T 28-03-2018 IPR013397 CRISPR-associated protein Csy1 MKLM6_RS09875 1afb0a2e82a48f1fe0744f9e4747c9e8 416 Pfam PF09611 CRISPR-associated protein (Cas_Csy1) 40 400 1.1E-120 T 28-03-2018 IPR013397 CRISPR-associated protein Csy1 MKLM6_RS11755 868633b582c4cd69d4f411fb4dd65d13 387 TIGRFAM TIGR01933 hflK: HflK protein 65 341 1.1E-95 T 28-03-2018 IPR010201 HflK GO:0016021 MKLM6_RS11755 868633b582c4cd69d4f411fb4dd65d13 387 Pfam PF01145 SPFH domain / Band 7 family 67 256 2.0E-28 T 28-03-2018 IPR001107 Band 7 domain MKLM6_RS11755 868633b582c4cd69d4f411fb4dd65d13 387 SMART SM00244 63 240 1.9E-27 T 28-03-2018 IPR001107 Band 7 domain MKLM6_RS11755 868633b582c4cd69d4f411fb4dd65d13 387 SUPERFAMILY SSF117892 122 246 2.62E-21 T 28-03-2018 IPR001107 Band 7 domain MKLM6_RS09800 3dc5e890cf24e240e584d99880ffeca2 62 Gene3D G3DSA:3.30.420.10 8 62 3.7E-8 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS09800 3dc5e890cf24e240e584d99880ffeca2 62 SUPERFAMILY SSF53098 11 59 2.28E-6 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS09800 3dc5e890cf24e240e584d99880ffeca2 62 Pfam PF13683 Integrase core domain 9 54 1.1E-13 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MKLM6_RS20420 ac736b72b464340ab78b14aa44e004d8 782 SUPERFAMILY SSF56601 416 765 2.82E-126 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MKLM6_RS20420 ac736b72b464340ab78b14aa44e004d8 782 SUPERFAMILY SSF56601 224 246 2.82E-126 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MKLM6_RS20420 ac736b72b464340ab78b14aa44e004d8 782 SUPERFAMILY SSF56601 275 326 2.82E-126 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MKLM6_RS20420 ac736b72b464340ab78b14aa44e004d8 782 Pfam PF00912 Transglycosylase 70 242 4.4E-63 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 MKLM6_RS20420 ac736b72b464340ab78b14aa44e004d8 782 SUPERFAMILY SSF53955 55 264 4.5E-76 T 28-03-2018 IPR023346 Lysozyme-like domain MKLM6_RS20420 ac736b72b464340ab78b14aa44e004d8 782 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 78 714 9.2E-182 T 28-03-2018 MKLM6_RS20420 ac736b72b464340ab78b14aa44e004d8 782 Gene3D G3DSA:1.10.3810.10 61 255 1.9E-77 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 MKLM6_RS20420 ac736b72b464340ab78b14aa44e004d8 782 Pfam PF17092 Penicillin-binding protein OB-like domain 348 419 2.0E-11 T 28-03-2018 IPR031376 Penicillin-binding protein, OB-like domain MKLM6_RS20420 ac736b72b464340ab78b14aa44e004d8 782 Pfam PF00905 Penicillin binding protein transpeptidase domain 421 666 1.1E-33 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MKLM6_RS20420 ac736b72b464340ab78b14aa44e004d8 782 Gene3D G3DSA:3.40.710.10 256 729 5.9E-121 T 28-03-2018 MKLM6_RS21915 8e2cf62cfa1f71e2be7e4235779e50c9 377 Pfam PF00437 Type II/IV secretion system protein 8 270 7.1E-34 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 MKLM6_RS21915 8e2cf62cfa1f71e2be7e4235779e50c9 377 Gene3D G3DSA:3.30.450.90 1 100 3.2E-21 T 28-03-2018 MKLM6_RS21915 8e2cf62cfa1f71e2be7e4235779e50c9 377 SUPERFAMILY SSF52540 6 336 2.05E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS21915 8e2cf62cfa1f71e2be7e4235779e50c9 377 Gene3D G3DSA:3.40.50.300 115 271 4.6E-26 T 28-03-2018 MKLM6_RS21915 8e2cf62cfa1f71e2be7e4235779e50c9 377 Gene3D G3DSA:3.40.50.300 272 347 3.5E-13 T 28-03-2018 MKLM6_RS21915 8e2cf62cfa1f71e2be7e4235779e50c9 377 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 344 3.5E-133 T 28-03-2018 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 MKLM6_RS21915 8e2cf62cfa1f71e2be7e4235779e50c9 377 SMART SM00382 122 247 4.7E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS00985 ade61e4bbc69a51d8f5303a49b80d1be 546 TIGRFAM TIGR01447 recD: exodeoxyribonuclease V, alpha subunit 69 537 1.6E-149 T 28-03-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 MKLM6_RS00985 ade61e4bbc69a51d8f5303a49b80d1be 546 Pfam PF13538 UvrD-like helicase C-terminal domain 466 511 2.1E-15 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain MKLM6_RS00985 ade61e4bbc69a51d8f5303a49b80d1be 546 SUPERFAMILY SSF52540 25 302 7.47E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS00985 ade61e4bbc69a51d8f5303a49b80d1be 546 SMART SM00382 137 413 0.0089 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS00985 ade61e4bbc69a51d8f5303a49b80d1be 546 Gene3D G3DSA:3.40.50.300 85 315 7.3E-49 T 28-03-2018 MKLM6_RS00985 ade61e4bbc69a51d8f5303a49b80d1be 546 Gene3D G3DSA:3.40.50.300 316 526 4.7E-26 T 28-03-2018 MKLM6_RS00985 ade61e4bbc69a51d8f5303a49b80d1be 546 SUPERFAMILY SSF52540 367 535 2.17E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS00985 ade61e4bbc69a51d8f5303a49b80d1be 546 SUPERFAMILY SSF52540 254 318 2.17E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS00985 ade61e4bbc69a51d8f5303a49b80d1be 546 Hamap MF_01487 RecBCD enzyme subunit RecD [recD]. 7 535 47.987 T 28-03-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 MKLM6_RS00985 ade61e4bbc69a51d8f5303a49b80d1be 546 Pfam PF13604 AAA domain 128 328 1.6E-34 T 28-03-2018 MKLM6_RS15890 3836d63d578d321106328e1d4aa2701e 356 SUPERFAMILY SSF51735 1 347 2.39E-90 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS15890 3836d63d578d321106328e1d4aa2701e 356 Gene3D G3DSA:3.40.50.720 1 193 1.1E-37 T 28-03-2018 MKLM6_RS15890 3836d63d578d321106328e1d4aa2701e 356 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 324 1.1E-100 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS15890 3836d63d578d321106328e1d4aa2701e 356 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 3 337 4.4E-155 T 28-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 MKLM6_RS15890 3836d63d578d321106328e1d4aa2701e 356 Gene3D G3DSA:3.90.25.10 194 354 5.0E-50 T 28-03-2018 MKLM6_RS02480 e24603434a5b0418a7e4c79c037fa175 119 Pfam PF01844 HNH endonuclease 36 84 3.7E-11 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 MKLM6_RS02480 e24603434a5b0418a7e4c79c037fa175 119 SMART SM00507 24 79 0.002 T 28-03-2018 IPR003615 HNH nuclease MKLM6_RS02480 e24603434a5b0418a7e4c79c037fa175 119 Gene3D G3DSA:3.40.1800.10 13 96 9.4E-8 T 28-03-2018 MKLM6_RS20600 7ae22f594de6f6f927bb3d4b458ea03d 80 SUPERFAMILY SSF143880 1 75 8.11E-22 T 28-03-2018 IPR018841 Protein of unknown function DUF2442 MKLM6_RS20600 7ae22f594de6f6f927bb3d4b458ea03d 80 Gene3D G3DSA:3.30.2020.10 1 77 3.5E-23 T 28-03-2018 IPR018841 Protein of unknown function DUF2442 MKLM6_RS20600 7ae22f594de6f6f927bb3d4b458ea03d 80 Pfam PF10387 Protein of unknown function (DUF2442) 5 75 3.1E-19 T 28-03-2018 IPR018841 Protein of unknown function DUF2442 MKLM6_RS06340 7a51e695d84e8d8dd54d5b7b0f8856a8 620 Gene3D G3DSA:3.40.50.970 296 485 2.2E-61 T 28-03-2018 MKLM6_RS06340 7a51e695d84e8d8dd54d5b7b0f8856a8 620 ProSitePatterns PS00802 Transketolase signature 2. 425 441 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MKLM6_RS06340 7a51e695d84e8d8dd54d5b7b0f8856a8 620 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 9 620 46.186 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MKLM6_RS06340 7a51e695d84e8d8dd54d5b7b0f8856a8 620 SUPERFAMILY SSF52518 318 503 9.7E-57 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS06340 7a51e695d84e8d8dd54d5b7b0f8856a8 620 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 10 281 3.6E-124 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MKLM6_RS06340 7a51e695d84e8d8dd54d5b7b0f8856a8 620 ProSitePatterns PS00801 Transketolase signature 1. 35 54 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MKLM6_RS06340 7a51e695d84e8d8dd54d5b7b0f8856a8 620 SUPERFAMILY SSF52922 491 618 6.81E-33 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MKLM6_RS06340 7a51e695d84e8d8dd54d5b7b0f8856a8 620 SMART SM00861 319 483 2.3E-64 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MKLM6_RS06340 7a51e695d84e8d8dd54d5b7b0f8856a8 620 Pfam PF02780 Transketolase, C-terminal domain 495 611 9.7E-28 T 28-03-2018 IPR033248 Transketolase, C-terminal domain MKLM6_RS06340 7a51e695d84e8d8dd54d5b7b0f8856a8 620 Pfam PF02779 Transketolase, pyrimidine binding domain 320 479 3.3E-36 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MKLM6_RS06340 7a51e695d84e8d8dd54d5b7b0f8856a8 620 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 12 618 7.3E-271 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MKLM6_RS06340 7a51e695d84e8d8dd54d5b7b0f8856a8 620 SUPERFAMILY SSF52518 5 198 1.46E-78 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS06340 7a51e695d84e8d8dd54d5b7b0f8856a8 620 SUPERFAMILY SSF52518 242 381 1.46E-78 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS06340 7a51e695d84e8d8dd54d5b7b0f8856a8 620 Gene3D G3DSA:3.40.50.920 495 620 3.2E-36 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MKLM6_RS06340 7a51e695d84e8d8dd54d5b7b0f8856a8 620 Gene3D G3DSA:3.40.50.970 1 295 4.1E-83 T 28-03-2018 MKLM6_RS16405 54793c357f6e826b7ea08197c0bed6e3 371 PIRSF PIRSF005572 1 371 2.7E-117 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 MKLM6_RS16405 54793c357f6e826b7ea08197c0bed6e3 371 Gene3D G3DSA:3.40.640.10 10 242 1.3E-44 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS16405 54793c357f6e826b7ea08197c0bed6e3 371 Pfam PF00266 Aminotransferase class-V 2 357 1.9E-65 T 28-03-2018 IPR000192 Aminotransferase class V domain MKLM6_RS16405 54793c357f6e826b7ea08197c0bed6e3 371 SUPERFAMILY SSF53383 1 364 9.97E-88 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS16405 54793c357f6e826b7ea08197c0bed6e3 371 Gene3D G3DSA:3.90.1150.10 243 357 9.2E-39 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS04275 dbfb0b1fe68a63fc724c2ec77184d698 474 Pfam PF10145 Phage-related minor tail protein 9 168 7.8E-12 T 28-03-2018 IPR010090 Phage tail tape measure protein MKLM6_RS19200 2c13e705251d39fa7902eb55979d5c79 190 Gene3D G3DSA:2.60.40.680 18 161 3.6E-14 T 28-03-2018 MKLM6_RS19200 2c13e705251d39fa7902eb55979d5c79 190 SUPERFAMILY SSF49384 26 160 3.89E-11 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 MKLM6_RS01900 3b4619d1d721b1ffb45c460a2aeb621c 160 PIRSF PIRSF024492 1 159 2.0E-32 T 28-03-2018 IPR014519 Uncharacterised conserved protein UCP024492 MKLM6_RS01900 3b4619d1d721b1ffb45c460a2aeb621c 160 Pfam PF04343 Protein of unknown function, DUF488 14 130 3.7E-26 T 28-03-2018 IPR007438 Protein of unknown function DUF488 MKLM6_RS17690 dcb8b2ec85d0737c2f5eb1f61e58a6a1 212 TIGRFAM TIGR03424 urea_degr_1: urea carboxylase-associated protein 1 13 211 5.7E-105 T 28-03-2018 IPR017791 Urea carboxylase-associated protein 1 MKLM6_RS17690 dcb8b2ec85d0737c2f5eb1f61e58a6a1 212 Pfam PF09347 Domain of unknown function (DUF1989) 18 185 1.9E-66 T 28-03-2018 IPR018959 Domain of unknown function DUF1989 MKLM6_RS09705 572c04f3c06c7cbfd3bd78039be3f38e 374 Pfam PF06727 Protein of unknown function (DUF1207) 42 374 1.8E-166 T 28-03-2018 IPR009599 Protein of unknown function DUF1207 MKLM6_RS09705 572c04f3c06c7cbfd3bd78039be3f38e 374 Gene3D G3DSA:2.40.160.20 144 374 1.8E-4 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MKLM6_RS13525 05813e7ef18a1de9d1befa60c68dfee8 203 Gene3D G3DSA:1.10.10.60 8 43 7.8E-7 T 28-03-2018 MKLM6_RS13525 05813e7ef18a1de9d1befa60c68dfee8 203 SUPERFAMILY SSF48498 92 194 1.19E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MKLM6_RS13525 05813e7ef18a1de9d1befa60c68dfee8 203 Gene3D G3DSA:1.10.357.10 84 197 2.0E-8 T 28-03-2018 MKLM6_RS13525 05813e7ef18a1de9d1befa60c68dfee8 203 SUPERFAMILY SSF46689 13 87 9.23E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS13525 05813e7ef18a1de9d1befa60c68dfee8 203 Gene3D G3DSA:1.10.260.40 44 83 8.6E-4 T 28-03-2018 MKLM6_RS13525 05813e7ef18a1de9d1befa60c68dfee8 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 67 2.2E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MKLM6_RS21200 52273e88484d63f37ecaf0176e35da13 249 Gene3D G3DSA:3.20.20.220 1 229 8.5E-27 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like MKLM6_RS21200 52273e88484d63f37ecaf0176e35da13 249 SUPERFAMILY SSF51730 2 232 8.24E-35 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like MKLM6_RS21200 52273e88484d63f37ecaf0176e35da13 249 Pfam PF02219 Methylenetetrahydrofolate reductase 74 202 1.5E-8 T 28-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 MKLM6_RS11915 1737c0756f12ec14835354c7506770f1 116 Pfam PF08888 HopJ type III effector protein 4 113 2.4E-47 T 28-03-2018 IPR014984 HopJ type III effector protein MKLM6_RS11915 1737c0756f12ec14835354c7506770f1 116 Gene3D G3DSA:3.20.160.10 2 114 6.5E-47 T 28-03-2018 MKLM6_RS09270 b28f46e493f87f50cf3698a7ab6860f1 357 SUPERFAMILY SSF53448 5 139 3.28E-47 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS09270 b28f46e493f87f50cf3698a7ab6860f1 357 SUPERFAMILY SSF53448 172 242 3.28E-47 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS09270 b28f46e493f87f50cf3698a7ab6860f1 357 Pfam PF00535 Glycosyl transferase family 2 8 155 1.2E-25 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MKLM6_RS09270 b28f46e493f87f50cf3698a7ab6860f1 357 Gene3D G3DSA:3.90.550.10 5 241 1.6E-40 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS11005 d6f2c5646b267cb796f7d357e915c277 391 Pfam PF10388 EAL-domain associated signalling protein domain 249 386 9.3E-15 T 28-03-2018 IPR018842 YkuI, C-terminal MKLM6_RS11005 d6f2c5646b267cb796f7d357e915c277 391 Pfam PF00563 EAL domain 4 229 4.3E-45 T 28-03-2018 IPR001633 EAL domain MKLM6_RS11005 d6f2c5646b267cb796f7d357e915c277 391 SUPERFAMILY SSF141868 4 230 1.31E-47 T 28-03-2018 IPR001633 EAL domain MKLM6_RS11005 d6f2c5646b267cb796f7d357e915c277 391 Gene3D G3DSA:3.20.20.450 2 253 3.8E-48 T 28-03-2018 IPR001633 EAL domain MKLM6_RS11005 d6f2c5646b267cb796f7d357e915c277 391 SMART SM00052 3 235 7.4E-21 T 28-03-2018 IPR001633 EAL domain MKLM6_RS11005 d6f2c5646b267cb796f7d357e915c277 391 Gene3D G3DSA:3.30.450.20 285 389 1.3E-10 T 28-03-2018 MKLM6_RS11005 d6f2c5646b267cb796f7d357e915c277 391 SUPERFAMILY SSF103190 258 386 7.85E-24 T 28-03-2018 IPR029151 Periplasmic sensor domain-like MKLM6_RS12560 dbd7b65b1efd7e0c7b533faf94f3e335 165 Gene3D G3DSA:1.10.3760.10 52 165 6.2E-34 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 MKLM6_RS12560 dbd7b65b1efd7e0c7b533faf94f3e335 165 PIRSF PIRSF006162 15 165 1.1E-46 T 28-03-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 MKLM6_RS12560 dbd7b65b1efd7e0c7b533faf94f3e335 165 SUPERFAMILY SSF101307 20 164 1.96E-39 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 MKLM6_RS12560 dbd7b65b1efd7e0c7b533faf94f3e335 165 Pfam PF04608 Phosphatidylglycerophosphatase A 26 164 2.7E-48 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 MKLM6_RS20015 397f55c3587d0f0d4340805d1c8a3a37 261 Gene3D G3DSA:3.40.50.1820 17 257 8.4E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS20015 397f55c3587d0f0d4340805d1c8a3a37 261 SUPERFAMILY SSF53474 9 259 9.1E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS20015 397f55c3587d0f0d4340805d1c8a3a37 261 Pfam PF01738 Dienelactone hydrolase family 34 258 1.2E-50 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 MKLM6_RS19920 d6b7993d5bea641be08ef53bd4911de0 188 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 15 186 2.5E-33 T 28-03-2018 IPR010664 Lipopolysaccharide assembly, LptC-related MKLM6_RS19920 d6b7993d5bea641be08ef53bd4911de0 188 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 9 185 2.2E-37 T 28-03-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 MKLM6_RS05485 048bed04891abcbd882eaa7ed81f3077 195 Pfam PF09335 SNARE associated Golgi protein 33 157 6.8E-18 T 28-03-2018 IPR032816 SNARE associated Golgi protein MKLM6_RS00105 3c066bef698d00370042e6faf92cf59a 168 Pfam PF09351 Domain of unknown function (DUF1993) 4 164 6.1E-58 T 28-03-2018 IPR018531 Domain of unknown function DUF1993 MKLM6_RS00105 3c066bef698d00370042e6faf92cf59a 168 SUPERFAMILY SSF109854 4 166 1.1E-57 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MKLM6_RS00105 3c066bef698d00370042e6faf92cf59a 168 Gene3D G3DSA:1.20.120.450 2 167 4.8E-62 T 28-03-2018 MKLM6_RS15635 a7542ad28038adb601984bc3a8c28f1f 147 SUPERFAMILY SSF54637 5 144 4.08E-48 T 28-03-2018 IPR029069 HotDog domain MKLM6_RS15635 a7542ad28038adb601984bc3a8c28f1f 147 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 5 143 1.1E-59 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MKLM6_RS15635 a7542ad28038adb601984bc3a8c28f1f 147 Gene3D G3DSA:3.10.129.10 1 146 1.2E-54 T 28-03-2018 MKLM6_RS15635 a7542ad28038adb601984bc3a8c28f1f 147 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 5 146 34.397 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MKLM6_RS15635 a7542ad28038adb601984bc3a8c28f1f 147 Pfam PF07977 FabA-like domain 14 138 8.0E-37 T 28-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MKLM6_RS11855 a584cffbf2096732184806943a1c0f2b 326 Pfam PF00072 Response regulator receiver domain 8 109 1.2E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS11855 a584cffbf2096732184806943a1c0f2b 326 SMART SM00448 5 117 2.0E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS11855 a584cffbf2096732184806943a1c0f2b 326 SUPERFAMILY SSF109604 128 315 5.02E-39 T 28-03-2018 MKLM6_RS11855 a584cffbf2096732184806943a1c0f2b 326 Pfam PF01966 HD domain 152 274 1.6E-21 T 28-03-2018 IPR006674 HD domain MKLM6_RS11855 a584cffbf2096732184806943a1c0f2b 326 Gene3D G3DSA:1.10.3210.10 125 324 1.7E-46 T 28-03-2018 MKLM6_RS11855 a584cffbf2096732184806943a1c0f2b 326 SMART SM00471 147 284 1.0E-7 T 28-03-2018 IPR003607 HD/PDEase domain MKLM6_RS11855 a584cffbf2096732184806943a1c0f2b 326 Gene3D G3DSA:3.40.50.2300 1 124 1.2E-34 T 28-03-2018 MKLM6_RS11855 a584cffbf2096732184806943a1c0f2b 326 SUPERFAMILY SSF52172 4 127 1.15E-37 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS05065 d225e5c7dc0992a5033258d2bf8451e2 75 Pfam PF11197 Protein of unknown function (DUF2835) 7 73 8.7E-25 T 28-03-2018 IPR021363 Protein of unknown function DUF2835 MKLM6_RS20000 0ef1f16fcdf83c56c05c3e197369a418 150 SMART SM00267 27 135 2.5E-6 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS20000 0ef1f16fcdf83c56c05c3e197369a418 150 Pfam PF00990 Diguanylate cyclase, GGDEF domain 61 130 1.8E-12 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS20000 0ef1f16fcdf83c56c05c3e197369a418 150 Gene3D G3DSA:3.30.70.270 58 138 4.1E-17 T 28-03-2018 MKLM6_RS20000 0ef1f16fcdf83c56c05c3e197369a418 150 SUPERFAMILY SSF55073 15 136 1.8E-17 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS20000 0ef1f16fcdf83c56c05c3e197369a418 150 Gene3D G3DSA:3.30.450.20 5 57 3.5E-4 T 28-03-2018 MKLM6_RS01610 915fd83744261ebe2e6d418ccf148230 880 Pfam PF01433 Peptidase family M1 domain 217 447 2.0E-56 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MKLM6_RS01610 915fd83744261ebe2e6d418ccf148230 880 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 558 880 5.8E-128 T 28-03-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal MKLM6_RS01610 915fd83744261ebe2e6d418ccf148230 880 Gene3D G3DSA:1.10.390.10 288 451 5.5E-51 T 28-03-2018 MKLM6_RS01610 915fd83744261ebe2e6d418ccf148230 880 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 321 333 2.7E-9 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MKLM6_RS01610 915fd83744261ebe2e6d418ccf148230 880 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 302 317 2.7E-9 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MKLM6_RS01610 915fd83744261ebe2e6d418ccf148230 880 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 134 149 2.7E-9 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MKLM6_RS01610 915fd83744261ebe2e6d418ccf148230 880 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 266 276 2.7E-9 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MKLM6_RS01610 915fd83744261ebe2e6d418ccf148230 880 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 184 199 2.7E-9 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MKLM6_RS01610 915fd83744261ebe2e6d418ccf148230 880 SUPERFAMILY SSF63737 6 200 1.12E-38 T 28-03-2018 MKLM6_RS01610 915fd83744261ebe2e6d418ccf148230 880 SUPERFAMILY SSF55486 211 459 1.76E-74 T 28-03-2018 MKLM6_RS01610 915fd83744261ebe2e6d418ccf148230 880 Gene3D G3DSA:1.25.50.10 556 880 2.8E-133 T 28-03-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal MKLM6_RS01610 915fd83744261ebe2e6d418ccf148230 880 Gene3D G3DSA:2.60.40.1730 16 201 1.6E-26 T 28-03-2018 MKLM6_RS01610 915fd83744261ebe2e6d418ccf148230 880 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 13 879 0.0 T 28-03-2018 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 MKLM6_RS01610 915fd83744261ebe2e6d418ccf148230 880 Pfam PF11940 Domain of unknown function (DUF3458) Ig-like fold 452 553 1.4E-29 T 28-03-2018 IPR035414 Peptidase M1, alanyl aminopeptidase, Ig-like fold MKLM6_RS16180 608733e675f95e07fed25b4793021748 147 Gene3D G3DSA:1.10.10.10 1 143 5.8E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS16180 608733e675f95e07fed25b4793021748 147 Pfam PF01638 HxlR-like helix-turn-helix 20 104 6.2E-20 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type MKLM6_RS16180 608733e675f95e07fed25b4793021748 147 SUPERFAMILY SSF46785 5 141 1.31E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS19600 3fea78c7803063e915b127c0220c2d10 653 Pfam PF07715 TonB-dependent Receptor Plug Domain 40 149 1.1E-20 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS19600 3fea78c7803063e915b127c0220c2d10 653 SUPERFAMILY SSF56935 31 653 1.5E-103 T 28-03-2018 MKLM6_RS19600 3fea78c7803063e915b127c0220c2d10 653 Pfam PF00593 TonB dependent receptor 169 652 1.7E-35 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS19600 3fea78c7803063e915b127c0220c2d10 653 Gene3D G3DSA:2.170.130.10 18 158 6.4E-29 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS19600 3fea78c7803063e915b127c0220c2d10 653 Gene3D G3DSA:2.40.170.20 159 653 9.6E-68 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS04105 b689d4e8a3e5c16b6a3a3632cb698647 189 Gene3D G3DSA:2.60.120.380 9 149 4.5E-6 T 28-03-2018 MKLM6_RS02595 02e2d4b74fcce2d84606c2042de7a605 378 Gene3D G3DSA:3.60.40.10 140 377 1.6E-16 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS02595 02e2d4b74fcce2d84606c2042de7a605 378 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 188 377 8.3E-30 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS02595 02e2d4b74fcce2d84606c2042de7a605 378 SUPERFAMILY SSF52172 1 132 1.71E-38 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS02595 02e2d4b74fcce2d84606c2042de7a605 378 Pfam PF00072 Response regulator receiver domain 3 114 1.1E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS02595 02e2d4b74fcce2d84606c2042de7a605 378 SMART SM00331 163 377 1.9E-9 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS02595 02e2d4b74fcce2d84606c2042de7a605 378 SMART SM00448 1 114 1.5E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS02595 02e2d4b74fcce2d84606c2042de7a605 378 Gene3D G3DSA:3.40.50.2300 1 139 1.7E-37 T 28-03-2018 MKLM6_RS05960 d17eb28ce5eca4546be879b5e97fb96c 312 SUPERFAMILY SSF53335 98 264 2.05E-24 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS05960 d17eb28ce5eca4546be879b5e97fb96c 312 Pfam PF13489 Methyltransferase domain 103 252 1.2E-14 T 28-03-2018 MKLM6_RS05960 d17eb28ce5eca4546be879b5e97fb96c 312 Gene3D G3DSA:3.40.50.150 15 288 9.2E-19 T 28-03-2018 MKLM6_RS07810 e4d40093cc806ef7c813f41110f0a5f9 176 Gene3D G3DSA:3.30.70.1290 3 149 4.4E-24 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS07810 e4d40093cc806ef7c813f41110f0a5f9 176 SUPERFAMILY SSF143422 11 149 3.14E-19 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS07810 e4d40093cc806ef7c813f41110f0a5f9 176 SMART SM01321 10 143 1.1E-8 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS16845 374ae126e4b9ade514833e1d2652f973 348 Gene3D G3DSA:3.40.50.450 98 248 2.1E-39 T 28-03-2018 MKLM6_RS16845 374ae126e4b9ade514833e1d2652f973 348 SUPERFAMILY SSF102405 66 272 1.47E-46 T 28-03-2018 MKLM6_RS16845 374ae126e4b9ade514833e1d2652f973 348 Gene3D G3DSA:1.10.10.10 264 345 1.9E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS16845 374ae126e4b9ade514833e1d2652f973 348 Pfam PF02481 DNA recombination-mediator protein A 59 263 5.5E-78 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 MKLM6_RS16845 374ae126e4b9ade514833e1d2652f973 348 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 55 272 2.5E-78 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 MKLM6_RS12405 a577ca9ca15fa83833c5d0bff8af4c98 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 60 2.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MKLM6_RS12405 a577ca9ca15fa83833c5d0bff8af4c98 207 Pfam PF13305 WHG domain 89 169 1.6E-11 T 28-03-2018 IPR025996 WHG domain MKLM6_RS12405 a577ca9ca15fa83833c5d0bff8af4c98 207 Gene3D G3DSA:1.10.10.60 1 43 1.0E-9 T 28-03-2018 MKLM6_RS12405 a577ca9ca15fa83833c5d0bff8af4c98 207 Gene3D G3DSA:1.10.260.40 44 65 0.0013 T 28-03-2018 MKLM6_RS12405 a577ca9ca15fa83833c5d0bff8af4c98 207 Gene3D G3DSA:1.10.357.10 66 196 2.2E-18 T 28-03-2018 MKLM6_RS12405 a577ca9ca15fa83833c5d0bff8af4c98 207 SUPERFAMILY SSF48498 84 193 1.59E-14 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MKLM6_RS12405 a577ca9ca15fa83833c5d0bff8af4c98 207 SUPERFAMILY SSF46689 1 76 3.54E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS21370 21b94d5d39b9607a0aba25446493bd8a 406 Gene3D G3DSA:3.40.390.10 129 375 2.6E-14 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 MKLM6_RS13675 68f40b276c69cd896d5d0ab1d14eb59c 111 SUPERFAMILY SSF46626 1 110 6.94E-10 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS13675 68f40b276c69cd896d5d0ab1d14eb59c 111 Gene3D G3DSA:1.10.760.10 11 111 2.3E-8 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS13810 b8ff9318a03fb1323dc20ffc4b945526 397 SMART SM00244 72 248 1.6E-26 T 28-03-2018 IPR001107 Band 7 domain MKLM6_RS13810 b8ff9318a03fb1323dc20ffc4b945526 397 SUPERFAMILY SSF117892 142 254 3.4E-21 T 28-03-2018 IPR001107 Band 7 domain MKLM6_RS13810 b8ff9318a03fb1323dc20ffc4b945526 397 Pfam PF12221 Bacterial membrane protein N terminal 1 44 1.8E-16 T 28-03-2018 IPR020980 Menbrane protein HflK, N-terminal MKLM6_RS13810 b8ff9318a03fb1323dc20ffc4b945526 397 TIGRFAM TIGR01933 hflK: HflK protein 74 350 3.0E-98 T 28-03-2018 IPR010201 HflK GO:0016021 MKLM6_RS13810 b8ff9318a03fb1323dc20ffc4b945526 397 Pfam PF01145 SPFH domain / Band 7 family 76 263 1.9E-27 T 28-03-2018 IPR001107 Band 7 domain MKLM6_RS11800 e2dd08923a38cd2c3b31cce615571c5f 302 SUPERFAMILY SSF51735 6 296 9.49E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS11800 e2dd08923a38cd2c3b31cce615571c5f 302 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 6 295 1.5E-101 T 28-03-2018 IPR010099 Epimerase family protein SDR39U1 MKLM6_RS11800 e2dd08923a38cd2c3b31cce615571c5f 302 Gene3D G3DSA:3.40.50.720 5 302 3.9E-40 T 28-03-2018 MKLM6_RS11800 e2dd08923a38cd2c3b31cce615571c5f 302 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 218 1.4E-20 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MKLM6_RS11800 e2dd08923a38cd2c3b31cce615571c5f 302 Pfam PF08338 Domain of unknown function (DUF1731) 253 298 2.1E-19 T 28-03-2018 IPR013549 Domain of unknown function DUF1731 MKLM6_RS03115 df9375d78a927256dacab99122f1d633 400 Pfam PF00155 Aminotransferase class I and II 32 391 5.6E-45 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MKLM6_RS03115 df9375d78a927256dacab99122f1d633 400 SUPERFAMILY SSF53383 2 396 4.73E-89 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS03115 df9375d78a927256dacab99122f1d633 400 Gene3D G3DSA:3.40.640.10 67 293 2.8E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS03115 df9375d78a927256dacab99122f1d633 400 TIGRFAM TIGR03538 DapC_gpp: succinyldiaminopimelate transaminase 1 394 1.8E-199 T 28-03-2018 IPR019878 Succinyldiaminopimelate transaminase, DapC, beta/gammaproteobacteria GO:0009016|GO:0009089 MKLM6_RS03115 df9375d78a927256dacab99122f1d633 400 Gene3D G3DSA:3.90.1150.10 294 398 4.2E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS13195 b1bb59eb2fd51cebc5aa17eea84624a5 235 Gene3D G3DSA:3.10.450.70 19 81 4.8E-25 T 28-03-2018 MKLM6_RS13195 b1bb59eb2fd51cebc5aa17eea84624a5 235 Pfam PF10411 Disulfide bond isomerase protein N-terminus 27 80 1.4E-21 T 28-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal MKLM6_RS13195 b1bb59eb2fd51cebc5aa17eea84624a5 235 Pfam PF13098 Thioredoxin-like domain 113 232 7.8E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS13195 b1bb59eb2fd51cebc5aa17eea84624a5 235 SUPERFAMILY SSF52833 93 233 2.94E-36 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS13195 b1bb59eb2fd51cebc5aa17eea84624a5 235 SUPERFAMILY SSF54423 22 82 4.84E-15 T 28-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal MKLM6_RS13195 b1bb59eb2fd51cebc5aa17eea84624a5 235 Gene3D G3DSA:3.40.30.10 99 235 4.4E-24 T 28-03-2018 MKLM6_RS16940 7210ebead525b0db571f03b96ea6193a 339 TIGRFAM TIGR02193 heptsyl_trn_I: lipopolysaccharide heptosyltransferase I 2 325 4.6E-73 T 28-03-2018 IPR011908 Lipopolysaccharide heptosyltransferase I GO:0008920|GO:0009244 MKLM6_RS16940 7210ebead525b0db571f03b96ea6193a 339 Gene3D G3DSA:3.40.50.2000 172 334 3.8E-24 T 28-03-2018 MKLM6_RS16940 7210ebead525b0db571f03b96ea6193a 339 Gene3D G3DSA:3.40.50.2000 1 158 1.4E-39 T 28-03-2018 MKLM6_RS16940 7210ebead525b0db571f03b96ea6193a 339 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 82 287 2.0E-34 T 28-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 MKLM6_RS16940 7210ebead525b0db571f03b96ea6193a 339 SUPERFAMILY SSF53756 1 330 1.05E-65 T 28-03-2018 MKLM6_RS06945 971ff39c6a94177ee6c8d1ff94d2ddb8 70 Pfam PF00872 Transposase, Mutator family 19 64 3.8E-5 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS15705 4ae239a36c86647c0cc808fecdf4c7fe 318 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 288 37.842 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MKLM6_RS15705 4ae239a36c86647c0cc808fecdf4c7fe 318 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 286 3.2E-101 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MKLM6_RS15705 4ae239a36c86647c0cc808fecdf4c7fe 318 Pfam PF02401 LytB protein 3 285 1.3E-93 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MKLM6_RS19040 569e349c6e82e9e79c0dd380fa939512 495 Pfam PF12161 HsdM N-terminal domain 6 109 1.9E-8 T 28-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain MKLM6_RS19040 569e349c6e82e9e79c0dd380fa939512 495 SUPERFAMILY SSF53335 4 490 1.28E-115 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS19040 569e349c6e82e9e79c0dd380fa939512 495 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 283 307 8.6E-14 T 28-03-2018 MKLM6_RS19040 569e349c6e82e9e79c0dd380fa939512 495 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 166 180 8.6E-14 T 28-03-2018 MKLM6_RS19040 569e349c6e82e9e79c0dd380fa939512 495 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 253 265 8.6E-14 T 28-03-2018 MKLM6_RS19040 569e349c6e82e9e79c0dd380fa939512 495 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 142 158 8.6E-14 T 28-03-2018 MKLM6_RS19040 569e349c6e82e9e79c0dd380fa939512 495 Gene3D G3DSA:3.40.50.150 140 450 1.4E-50 T 28-03-2018 MKLM6_RS19040 569e349c6e82e9e79c0dd380fa939512 495 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 256 262 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MKLM6_RS19040 569e349c6e82e9e79c0dd380fa939512 495 Pfam PF02384 N-6 DNA Methylase 120 408 1.9E-73 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 MKLM6_RS03895 40f62a757c43f1cbb4baa433cef116fb 509 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 446 507 2.6E-10 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 MKLM6_RS03895 40f62a757c43f1cbb4baa433cef116fb 509 Gene3D G3DSA:3.30.1150.10 403 509 6.3E-22 T 28-03-2018 MKLM6_RS03895 40f62a757c43f1cbb4baa433cef116fb 509 TIGRFAM TIGR02794 tolA_full: protein TolA 238 508 4.6E-39 T 28-03-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 MKLM6_RS03895 40f62a757c43f1cbb4baa433cef116fb 509 SUPERFAMILY SSF74653 402 509 9.03E-20 T 28-03-2018 MKLM6_RS03895 40f62a757c43f1cbb4baa433cef116fb 509 Pfam PF13103 TonB C terminal 426 490 1.3E-11 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 MKLM6_RS03425 60304e971a5262d9623e3f339517ffbb 58 Gene3D G3DSA:2.10.70.10 22 58 1.9E-20 T 28-03-2018 MKLM6_RS03425 60304e971a5262d9623e3f339517ffbb 58 Pfam PF10636 Hemin uptake protein hemP 22 58 2.8E-19 T 28-03-2018 IPR019600 Hemin uptake protein HemP MKLM6_RS18690 cbcfcf300c3f20cc755e1ffeae35d64f 70 Hamap MF_00715 Protein SlyX [slyX]. 1 70 13.537 T 28-03-2018 IPR007236 SlyX MKLM6_RS18690 cbcfcf300c3f20cc755e1ffeae35d64f 70 Gene3D G3DSA:1.20.5.300 2 46 6.7E-18 T 28-03-2018 MKLM6_RS18690 cbcfcf300c3f20cc755e1ffeae35d64f 70 Pfam PF04102 SlyX 3 70 6.4E-23 T 28-03-2018 IPR007236 SlyX MKLM6_RS16480 1eced287f9011903ce43dfb9294b8e67 257 Gene3D G3DSA:3.40.50.300 2 257 3.6E-50 T 28-03-2018 MKLM6_RS16480 1eced287f9011903ce43dfb9294b8e67 257 SUPERFAMILY SSF52540 1 256 8.37E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS16480 1eced287f9011903ce43dfb9294b8e67 257 Pfam PF13614 AAA domain 5 185 3.0E-36 T 28-03-2018 IPR025669 AAA domain MKLM6_RS00260 7b1c07611f8c97b8b1e885f1f15fd97d 99 SUPERFAMILY SSF47413 9 89 3.67E-21 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MKLM6_RS00260 7b1c07611f8c97b8b1e885f1f15fd97d 99 Gene3D G3DSA:1.10.260.40 2 85 9.4E-9 T 28-03-2018 MKLM6_RS00260 7b1c07611f8c97b8b1e885f1f15fd97d 99 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 4 85 1.7E-31 T 28-03-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 MKLM6_RS00260 7b1c07611f8c97b8b1e885f1f15fd97d 99 Pfam PF01381 Helix-turn-helix 23 59 2.1E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MKLM6_RS05475 91650a7c341e28d3e75e70d6faca8576 207 SUPERFAMILY SSF51197 14 195 2.2E-9 T 28-03-2018 MKLM6_RS05475 91650a7c341e28d3e75e70d6faca8576 207 Gene3D G3DSA:2.60.120.620 16 198 6.6E-26 T 28-03-2018 MKLM6_RS05475 91650a7c341e28d3e75e70d6faca8576 207 Pfam PF13759 Putative 2OG-Fe(II) oxygenase 88 190 4.7E-23 T 28-03-2018 IPR012668 Conserved hypothetical protein CHP02466 MKLM6_RS15410 24d070e016606d05e87877262b535826 245 Gene3D G3DSA:3.40.630.30 13 242 9.3E-37 T 28-03-2018 MKLM6_RS15410 24d070e016606d05e87877262b535826 245 Pfam PF13444 Acetyltransferase (GNAT) domain 34 140 2.7E-18 T 28-03-2018 MKLM6_RS15410 24d070e016606d05e87877262b535826 245 TIGRFAM TIGR03694 exosort_acyl: N-acyl amino acid synthase, PEP-CTERM/exosortase system-associated 11 243 2.0E-68 T 28-03-2018 IPR022484 PEP-CTERM/exosortase system-associated acyltransferase, predicted MKLM6_RS15410 24d070e016606d05e87877262b535826 245 SUPERFAMILY SSF55729 15 237 1.68E-28 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS16675 11b7a091195ea2061fe4e3277d57e048 508 ProSitePatterns PS00982 Bacterial-type phytoene dehydrogenase signature. 461 481 - T 28-03-2018 IPR008150 Phytoene dehydrogenase, bacterial-type, conserved site MKLM6_RS16675 11b7a091195ea2061fe4e3277d57e048 508 PRINTS PR00419 Adrenodoxin reductase family signature 6 28 9.5E-8 T 28-03-2018 MKLM6_RS16675 11b7a091195ea2061fe4e3277d57e048 508 PRINTS PR00419 Adrenodoxin reductase family signature 29 42 9.5E-8 T 28-03-2018 MKLM6_RS16675 11b7a091195ea2061fe4e3277d57e048 508 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 8 495 6.0E-136 T 28-03-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 MKLM6_RS16675 11b7a091195ea2061fe4e3277d57e048 508 SUPERFAMILY SSF51905 451 491 2.2E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS16675 11b7a091195ea2061fe4e3277d57e048 508 SUPERFAMILY SSF51905 1 320 2.2E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS16675 11b7a091195ea2061fe4e3277d57e048 508 Gene3D G3DSA:3.50.50.60 2 493 7.0E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS16675 11b7a091195ea2061fe4e3277d57e048 508 Pfam PF01593 Flavin containing amine oxidoreductase 16 489 4.8E-25 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MKLM6_RS09025 28de62a23e93a8f73f0e9809f081b950 481 SUPERFAMILY SSF103190 94 173 1.02E-7 T 28-03-2018 IPR029151 Periplasmic sensor domain-like MKLM6_RS09025 28de62a23e93a8f73f0e9809f081b950 481 Gene3D G3DSA:3.30.450.20 29 177 1.0E-25 T 28-03-2018 MKLM6_RS09025 28de62a23e93a8f73f0e9809f081b950 481 SMART SM00387 365 476 5.5E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS09025 28de62a23e93a8f73f0e9809f081b950 481 Gene3D G3DSA:3.30.565.10 314 476 3.0E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS09025 28de62a23e93a8f73f0e9809f081b950 481 SUPERFAMILY SSF47384 241 319 1.29E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS09025 28de62a23e93a8f73f0e9809f081b950 481 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 368 474 6.9E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS09025 28de62a23e93a8f73f0e9809f081b950 481 Gene3D G3DSA:1.10.287.130 238 313 2.6E-11 T 28-03-2018 MKLM6_RS09025 28de62a23e93a8f73f0e9809f081b950 481 Pfam PF00512 His Kinase A (phospho-acceptor) domain 258 318 3.4E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS09025 28de62a23e93a8f73f0e9809f081b950 481 SUPERFAMILY SSF55874 310 474 3.54E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS09025 28de62a23e93a8f73f0e9809f081b950 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 416 7.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS09025 28de62a23e93a8f73f0e9809f081b950 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 473 7.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS09025 28de62a23e93a8f73f0e9809f081b950 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 430 7.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS09025 28de62a23e93a8f73f0e9809f081b950 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 436 454 7.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS09025 28de62a23e93a8f73f0e9809f081b950 481 SMART SM00388 255 320 2.1E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS05330 dc3c1b375a8fd327d27b18332e58f637 415 Gene3D G3DSA:3.20.20.140 63 370 8.9E-32 T 28-03-2018 MKLM6_RS05330 dc3c1b375a8fd327d27b18332e58f637 415 SUPERFAMILY SSF51556 67 365 2.78E-29 T 28-03-2018 IPR032466 Metal-dependent hydrolase MKLM6_RS05330 dc3c1b375a8fd327d27b18332e58f637 415 Pfam PF04909 Amidohydrolase 67 345 1.2E-13 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MKLM6_RS05725 9881561e8672d53f0685510c45009985 394 SUPERFAMILY SSF63446 330 377 1.08E-5 T 28-03-2018 IPR016134 Dockerin domain GO:0000272 MKLM6_RS05725 9881561e8672d53f0685510c45009985 394 SUPERFAMILY SSF49299 241 328 1.83E-7 T 28-03-2018 IPR000601 PKD domain MKLM6_RS05725 9881561e8672d53f0685510c45009985 394 Gene3D G3DSA:3.40.1850.10 247 334 1.1E-18 T 28-03-2018 MKLM6_RS20120 e26226866fcc534cf11a8b239b86ab53 314 Gene3D G3DSA:3.40.50.2300 129 279 3.0E-5 T 28-03-2018 MKLM6_RS20120 e26226866fcc534cf11a8b239b86ab53 314 Gene3D G3DSA:3.40.50.2300 22 126 1.3E-5 T 28-03-2018 MKLM6_RS20120 e26226866fcc534cf11a8b239b86ab53 314 Pfam PF04392 ABC transporter substrate binding protein 74 302 4.3E-14 T 28-03-2018 IPR007487 ABC transporter, substrate-binding protein MKLM6_RS13215 e922e3063e52cdf8b088dbd1fe0a7a80 253 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 14 242 40.765 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MKLM6_RS13215 e922e3063e52cdf8b088dbd1fe0a7a80 253 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 187 204 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 MKLM6_RS13215 e922e3063e52cdf8b088dbd1fe0a7a80 253 SUPERFAMILY SSF64005 13 237 3.79E-87 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MKLM6_RS13215 e922e3063e52cdf8b088dbd1fe0a7a80 253 Gene3D G3DSA:3.40.1180.10 3 245 2.3E-92 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MKLM6_RS13215 e922e3063e52cdf8b088dbd1fe0a7a80 253 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 15 241 1.7E-95 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MKLM6_RS13215 e922e3063e52cdf8b088dbd1fe0a7a80 253 Pfam PF01255 Putative undecaprenyl diphosphate synthase 21 241 2.7E-81 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MKLM6_RS00935 d4bf8aad60f57700fca8650dedb836c8 404 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 21 404 3.0E-127 T 28-03-2018 MKLM6_RS00935 d4bf8aad60f57700fca8650dedb836c8 404 Gene3D G3DSA:3.60.70.12 7 275 2.7E-102 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MKLM6_RS00935 d4bf8aad60f57700fca8650dedb836c8 404 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 12 404 7.5E-127 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MKLM6_RS00935 d4bf8aad60f57700fca8650dedb836c8 404 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 404 149.515 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MKLM6_RS00935 d4bf8aad60f57700fca8650dedb836c8 404 SUPERFAMILY SSF56266 14 401 1.83E-135 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MKLM6_RS00935 d4bf8aad60f57700fca8650dedb836c8 404 Pfam PF01960 ArgJ family 20 404 1.5E-144 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MKLM6_RS21985 84f9dbb0cb0ebf8587b6af1756416a7d 204 Gene3D G3DSA:3.40.50.300 80 185 1.4E-32 T 28-03-2018 MKLM6_RS21985 84f9dbb0cb0ebf8587b6af1756416a7d 204 Pfam PF00625 Guanylate kinase 4 182 1.5E-57 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit MKLM6_RS21985 84f9dbb0cb0ebf8587b6af1756416a7d 204 Gene3D G3DSA:3.30.63.10 50 79 2.1E-23 T 28-03-2018 MKLM6_RS21985 84f9dbb0cb0ebf8587b6af1756416a7d 204 ProSitePatterns PS00856 Guanylate kinase-like signature. 38 55 - T 28-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 MKLM6_RS21985 84f9dbb0cb0ebf8587b6af1756416a7d 204 Gene3D G3DSA:3.40.50.300 1 49 1.8E-4 T 28-03-2018 MKLM6_RS21985 84f9dbb0cb0ebf8587b6af1756416a7d 204 SUPERFAMILY SSF52540 3 186 3.64E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS21985 84f9dbb0cb0ebf8587b6af1756416a7d 204 SMART SM00072 3 185 3.1E-68 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit MKLM6_RS21985 84f9dbb0cb0ebf8587b6af1756416a7d 204 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 4 182 1.0E-73 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 MKLM6_RS21985 84f9dbb0cb0ebf8587b6af1756416a7d 204 Hamap MF_00328 Guanylate kinase [gmk]. 2 185 35.954 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 MKLM6_RS02125 21ab486834afeb8bdb1a98177dff508f 328 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 43 173 2.6E-62 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 MKLM6_RS02125 21ab486834afeb8bdb1a98177dff508f 328 PIRSF PIRSF002849 1 328 9.6E-125 T 28-03-2018 MKLM6_RS02125 21ab486834afeb8bdb1a98177dff508f 328 SUPERFAMILY SSF52540 8 300 4.37E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS02125 21ab486834afeb8bdb1a98177dff508f 328 Gene3D G3DSA:3.40.50.300 24 190 1.6E-24 T 28-03-2018 MKLM6_RS02125 21ab486834afeb8bdb1a98177dff508f 328 Gene3D G3DSA:1.10.8.300 210 325 7.0E-31 T 28-03-2018 MKLM6_RS02260 d7f37ba8b4f7fe307f248b83c7a43582 197 Pfam PF05685 Putative restriction endonuclease 13 173 2.4E-32 T 28-03-2018 IPR008538 Domain of unknown function DUF820 MKLM6_RS02260 d7f37ba8b4f7fe307f248b83c7a43582 197 Gene3D G3DSA:3.90.1570.10 1 189 6.6E-43 T 28-03-2018 MKLM6_RS02260 d7f37ba8b4f7fe307f248b83c7a43582 197 SUPERFAMILY SSF52980 5 181 2.14E-26 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MKLM6_RS12200 fb1cf4c8cd2f063ca49a8dc271d8f9ff 290 Gene3D G3DSA:2.40.170.20 2 290 3.0E-16 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS12200 fb1cf4c8cd2f063ca49a8dc271d8f9ff 290 SUPERFAMILY SSF56935 86 290 9.16E-12 T 28-03-2018 MKLM6_RS12200 fb1cf4c8cd2f063ca49a8dc271d8f9ff 290 SUPERFAMILY SSF56935 16 59 9.16E-12 T 28-03-2018 MKLM6_RS06915 ad216e5cba06268566fa636b17ee6ad7 247 Pfam PF09849 Uncharacterized protein conserved in bacteria (DUF2076) 32 241 2.8E-38 T 28-03-2018 IPR018648 Protein of unknown function DUF2076 MKLM6_RS21145 d47aab32d07f70b0eee1d3224a99e4f8 222 Pfam PF01618 MotA/TolQ/ExbB proton channel family 93 203 1.3E-37 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 MKLM6_RS12665 89f75d77b1742e6928c3c78396f7b6f9 206 SUPERFAMILY SSF51366 3 202 2.51E-58 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MKLM6_RS12665 89f75d77b1742e6928c3c78396f7b6f9 206 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 5 199 4.0E-43 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 MKLM6_RS12665 89f75d77b1742e6928c3c78396f7b6f9 206 Gene3D G3DSA:3.20.20.70 2 206 2.2E-67 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS12665 89f75d77b1742e6928c3c78396f7b6f9 206 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 3 205 40.235 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 MKLM6_RS07480 13d603140b0903622bb99c11b4244015 423 Gene3D G3DSA:1.10.3210.10 82 331 6.8E-36 T 28-03-2018 MKLM6_RS07480 13d603140b0903622bb99c11b4244015 423 Pfam PF11871 Domain of unknown function (DUF3391) 6 121 1.3E-19 T 28-03-2018 IPR021812 Protein of unknown function DUF3391 MKLM6_RS07480 13d603140b0903622bb99c11b4244015 423 Pfam PF13487 HD domain 219 279 1.5E-15 T 28-03-2018 MKLM6_RS07480 13d603140b0903622bb99c11b4244015 423 SUPERFAMILY SSF109604 158 328 1.21E-25 T 28-03-2018 MKLM6_RS07480 13d603140b0903622bb99c11b4244015 423 TIGRFAM TIGR00277 HDIG: HDIG domain 165 257 1.9E-11 T 28-03-2018 IPR006675 HDIG domain MKLM6_RS02760 a2c92ff2b6713077e1942f92f2359031 248 SUPERFAMILY SSF88659 92 157 2.57E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS02760 a2c92ff2b6713077e1942f92f2359031 248 Pfam PF04545 Sigma-70, region 4 184 233 6.6E-18 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS02760 a2c92ff2b6713077e1942f92f2359031 248 Pfam PF04539 Sigma-70 region 3 98 160 3.0E-10 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS02760 a2c92ff2b6713077e1942f92f2359031 248 Pfam PF04542 Sigma-70 region 2 18 91 4.5E-18 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS02760 a2c92ff2b6713077e1942f92f2359031 248 Gene3D G3DSA:1.10.10.10 92 140 9.1E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS02760 a2c92ff2b6713077e1942f92f2359031 248 Gene3D G3DSA:1.10.10.10 159 241 3.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS02760 a2c92ff2b6713077e1942f92f2359031 248 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 235 3.3E-35 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS02760 a2c92ff2b6713077e1942f92f2359031 248 Gene3D G3DSA:1.10.1740.10 4 88 3.6E-20 T 28-03-2018 MKLM6_RS02760 a2c92ff2b6713077e1942f92f2359031 248 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 18 235 5.3E-84 T 28-03-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS02760 a2c92ff2b6713077e1942f92f2359031 248 Hamap MF_00962 RNA polymerase sigma factor FliA [fliA]. 4 238 64.678 T 28-03-2018 IPR028617 RNA polymerase sigma factor FliA GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS02760 a2c92ff2b6713077e1942f92f2359031 248 PIRSF PIRSF000770 3 248 1.4E-39 T 28-03-2018 MKLM6_RS02760 a2c92ff2b6713077e1942f92f2359031 248 SUPERFAMILY SSF88659 160 239 3.18E-21 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS02760 a2c92ff2b6713077e1942f92f2359031 248 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 45 58 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS02760 a2c92ff2b6713077e1942f92f2359031 248 SUPERFAMILY SSF88946 14 90 1.7E-24 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS02760 a2c92ff2b6713077e1942f92f2359031 248 PRINTS PR00046 Major sigma-70 factor signature 188 200 3.0E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS02760 a2c92ff2b6713077e1942f92f2359031 248 PRINTS PR00046 Major sigma-70 factor signature 220 231 3.0E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS02760 a2c92ff2b6713077e1942f92f2359031 248 PRINTS PR00046 Major sigma-70 factor signature 205 220 3.0E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS02760 a2c92ff2b6713077e1942f92f2359031 248 PRINTS PR00046 Major sigma-70 factor signature 45 58 3.0E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS10235 0ebc533c50f707781bd222ae258a099d 1117 SMART SM00481 16 83 2.1E-15 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal MKLM6_RS10235 0ebc533c50f707781bd222ae258a099d 1117 SUPERFAMILY SSF89550 15 197 8.24E-12 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MKLM6_RS10235 0ebc533c50f707781bd222ae258a099d 1117 Gene3D G3DSA:3.20.20.140 13 231 5.1E-36 T 28-03-2018 MKLM6_RS10235 0ebc533c50f707781bd222ae258a099d 1117 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 281 550 7.3E-95 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS10235 0ebc533c50f707781bd222ae258a099d 1117 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 636 785 1.4E-48 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS10235 0ebc533c50f707781bd222ae258a099d 1117 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 15 1117 13.802 T 28-03-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS10235 0ebc533c50f707781bd222ae258a099d 1117 Pfam PF14579 Helix-hairpin-helix motif 859 948 7.0E-21 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS10235 0ebc533c50f707781bd222ae258a099d 1117 Pfam PF01336 OB-fold nucleic acid binding domain 1029 1101 4.5E-8 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MKLM6_RS10235 0ebc533c50f707781bd222ae258a099d 1117 Gene3D G3DSA:1.10.150.280 887 936 0.0036 T 28-03-2018 MKLM6_RS10235 0ebc533c50f707781bd222ae258a099d 1117 Pfam PF02811 PHP domain 17 126 5.6E-14 T 28-03-2018 IPR004013 PHP domain GO:0003824 MKLM6_RS10235 0ebc533c50f707781bd222ae258a099d 1117 Gene3D G3DSA:2.40.50.140 959 1106 4.0E-10 T 28-03-2018 MKLM6_RS19865 67b885acea00c90f83bdf95d718892b2 925 Gene3D G3DSA:3.20.20.80 37 366 2.3E-39 T 28-03-2018 MKLM6_RS19865 67b885acea00c90f83bdf95d718892b2 925 SUPERFAMILY SSF51445 194 358 8.89E-42 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily MKLM6_RS19865 67b885acea00c90f83bdf95d718892b2 925 SUPERFAMILY SSF51445 52 156 8.89E-42 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily MKLM6_RS19865 67b885acea00c90f83bdf95d718892b2 925 Gene3D G3DSA:3.90.550.10 453 739 7.0E-47 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS19865 67b885acea00c90f83bdf95d718892b2 925 SUPERFAMILY SSF53448 464 740 2.39E-54 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS19865 67b885acea00c90f83bdf95d718892b2 925 Pfam PF13641 Glycosyltransferase like family 2 480 707 1.7E-29 T 28-03-2018 MKLM6_RS19865 67b885acea00c90f83bdf95d718892b2 925 Pfam PF00332 Glycosyl hydrolases family 17 277 358 5.4E-7 T 28-03-2018 IPR000490 Glycoside hydrolase family 17 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.39 MKLM6_RS09545 fd0701609821d8e7003f9efdf1268b7c 251 Gene3D G3DSA:3.20.20.370 10 245 1.9E-26 T 28-03-2018 MKLM6_RS09545 fd0701609821d8e7003f9efdf1268b7c 251 Pfam PF01522 Polysaccharide deacetylase 30 176 2.9E-14 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MKLM6_RS09545 fd0701609821d8e7003f9efdf1268b7c 251 SUPERFAMILY SSF88713 10 244 5.44E-30 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MKLM6_RS09205 033f9f92e6fc39efbc2cd26aeb43d4e7 448 TIGRFAM TIGR03937 PgaC_IcaA: poly-beta-1,6 N-acetyl-D-glucosamine synthase 37 444 5.6E-179 T 28-03-2018 IPR023853 Poly-beta-1,6 N-acetyl-D-glucosamine synthase PgaC/IcaA GO:0008375|GO:0042710 MKLM6_RS09205 033f9f92e6fc39efbc2cd26aeb43d4e7 448 SUPERFAMILY SSF53448 77 355 3.38E-63 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS09205 033f9f92e6fc39efbc2cd26aeb43d4e7 448 Gene3D G3DSA:3.90.550.10 61 327 8.1E-59 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS09205 033f9f92e6fc39efbc2cd26aeb43d4e7 448 Pfam PF13641 Glycosyltransferase like family 2 80 302 3.3E-35 T 28-03-2018 MKLM6_RS08620 6262db8c697ae5ab0dc7b264988cfac2 358 Pfam PF04055 Radical SAM superfamily 69 246 8.0E-12 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS08620 6262db8c697ae5ab0dc7b264988cfac2 358 SMART SM00729 65 290 3.1E-4 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MKLM6_RS08620 6262db8c697ae5ab0dc7b264988cfac2 358 SUPERFAMILY SSF102114 47 265 3.53E-13 T 28-03-2018 MKLM6_RS08620 6262db8c697ae5ab0dc7b264988cfac2 358 Gene3D G3DSA:3.20.20.70 9 330 2.6E-27 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS20185 8f9dad14fea40ef15496b44fee1dc611 505 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 39 64 - T 28-03-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 MKLM6_RS20185 8f9dad14fea40ef15496b44fee1dc611 505 Pfam PF00374 Nickel-dependent hydrogenase 248 493 2.5E-55 T 28-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 MKLM6_RS20185 8f9dad14fea40ef15496b44fee1dc611 505 Pfam PF00374 Nickel-dependent hydrogenase 39 119 7.7E-16 T 28-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 MKLM6_RS20185 8f9dad14fea40ef15496b44fee1dc611 505 SUPERFAMILY SSF56762 10 202 1.57E-115 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS20185 8f9dad14fea40ef15496b44fee1dc611 505 SUPERFAMILY SSF56762 235 493 1.57E-115 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS20185 8f9dad14fea40ef15496b44fee1dc611 505 Gene3D G3DSA:1.10.645.10 122 493 3.1E-95 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS20185 8f9dad14fea40ef15496b44fee1dc611 505 Gene3D G3DSA:1.10.645.10 2 121 5.7E-28 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS07945 8f646b55151a597e93cfe2ecc07757e6 251 PIRSF PIRSF000349 19 245 5.6E-40 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MKLM6_RS07945 8f646b55151a597e93cfe2ecc07757e6 251 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 134 236 4.0E-21 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MKLM6_RS07945 8f646b55151a597e93cfe2ecc07757e6 251 SUPERFAMILY SSF54719 130 242 3.54E-28 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MKLM6_RS07945 8f646b55151a597e93cfe2ecc07757e6 251 SUPERFAMILY SSF46609 48 129 2.49E-13 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MKLM6_RS07945 8f646b55151a597e93cfe2ecc07757e6 251 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 5 30 0.0013 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal MKLM6_RS19190 34bcf987e7b83bc1f624ff27df40c643 211 SUPERFAMILY SSF49785 19 180 9.69E-10 T 28-03-2018 IPR008979 Galactose-binding domain-like MKLM6_RS19190 34bcf987e7b83bc1f624ff27df40c643 211 Pfam PF04862 Protein of unknown function (DUF642) 21 146 8.9E-10 T 28-03-2018 IPR006946 Domain of unknown function DUF642 MKLM6_RS19190 34bcf987e7b83bc1f624ff27df40c643 211 Gene3D G3DSA:2.60.120.260 19 190 1.4E-15 T 28-03-2018 IPR008979 Galactose-binding domain-like MKLM6_RS11235 4b390c8434552a21ca89663a03e722f8 349 SUPERFAMILY SSF53756 15 343 4.71E-23 T 28-03-2018 MKLM6_RS11235 4b390c8434552a21ca89663a03e722f8 349 Gene3D G3DSA:3.40.50.2000 148 345 7.5E-15 T 28-03-2018 MKLM6_RS11235 4b390c8434552a21ca89663a03e722f8 349 Pfam PF00534 Glycosyl transferases group 1 213 306 1.0E-7 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 MKLM6_RS19415 6c5c4e9ed61f421d771cfc9fec157da0 478 Pfam PF03600 Citrate transporter 50 423 2.9E-47 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 MKLM6_RS21310 d7b4a8c03fa9e59c623d862f9f1621b1 167 SUPERFAMILY SSF88659 89 165 1.37E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS21310 d7b4a8c03fa9e59c623d862f9f1621b1 167 Gene3D G3DSA:1.10.1740.10 6 64 3.8E-12 T 28-03-2018 MKLM6_RS21310 d7b4a8c03fa9e59c623d862f9f1621b1 167 SUPERFAMILY SSF88946 9 90 6.28E-12 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS21310 d7b4a8c03fa9e59c623d862f9f1621b1 167 Gene3D G3DSA:1.10.10.10 65 165 6.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS21310 d7b4a8c03fa9e59c623d862f9f1621b1 167 Pfam PF08281 Sigma-70, region 4 111 162 2.9E-17 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS21310 d7b4a8c03fa9e59c623d862f9f1621b1 167 Pfam PF04542 Sigma-70 region 2 10 75 5.2E-9 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS21310 d7b4a8c03fa9e59c623d862f9f1621b1 167 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 164 5.3E-24 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS22140 9477f66f99338ca8a44c478f4bfcdf34 568 SUPERFAMILY SSF56349 216 561 2.91E-35 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS22140 9477f66f99338ca8a44c478f4bfcdf34 568 Pfam PF12482 Phage integrase protein 82 165 4.0E-20 T 28-03-2018 IPR022169 Protein of unknown function DUF3701 MKLM6_RS22140 9477f66f99338ca8a44c478f4bfcdf34 568 Gene3D G3DSA:1.10.150.130 214 340 6.0E-14 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal MKLM6_RS22140 9477f66f99338ca8a44c478f4bfcdf34 568 Pfam PF00589 Phage integrase family 371 555 2.7E-18 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS22140 9477f66f99338ca8a44c478f4bfcdf34 568 Gene3D G3DSA:1.10.443.10 341 557 3.6E-30 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS09150 7cb66123d783fcd40926ddd5f9cdeb83 286 Pfam PF07238 PilZ domain 58 138 6.2E-10 T 28-03-2018 IPR009875 PilZ domain GO:0035438 MKLM6_RS09150 7cb66123d783fcd40926ddd5f9cdeb83 286 Gene3D G3DSA:2.40.10.220 13 143 8.2E-17 T 28-03-2018 MKLM6_RS01380 0075826c11618308ce7435e032c74c74 125 Pfam PF04234 CopC domain 28 123 1.8E-24 T 28-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 MKLM6_RS01380 0075826c11618308ce7435e032c74c74 125 Gene3D G3DSA:2.60.40.1220 27 124 2.0E-26 T 28-03-2018 MKLM6_RS01380 0075826c11618308ce7435e032c74c74 125 SUPERFAMILY SSF81296 27 124 5.88E-23 T 28-03-2018 IPR014756 Immunoglobulin E-set MKLM6_RS08900 8334515595b974d7370b27e6b7881980 151 Gene3D G3DSA:3.40.50.620 1 122 3.3E-7 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS08900 8334515595b974d7370b27e6b7881980 151 SUPERFAMILY SSF52402 1 115 7.03E-7 T 28-03-2018 MKLM6_RS00885 276061d3d8b35b14dc887875fa2e0666 107 Gene3D G3DSA:3.30.70.120 1 104 6.5E-40 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MKLM6_RS00885 276061d3d8b35b14dc887875fa2e0666 107 SUPERFAMILY SSF102705 2 103 3.26E-22 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 MKLM6_RS03765 14d9c1ee22f4211c157ff88584bfdc30 390 SUPERFAMILY SSF51004 24 388 5.1E-73 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain MKLM6_RS03765 14d9c1ee22f4211c157ff88584bfdc30 390 Pfam PF02239 Cytochrome D1 heme domain 25 384 9.0E-113 T 28-03-2018 MKLM6_RS03765 14d9c1ee22f4211c157ff88584bfdc30 390 Gene3D G3DSA:2.140.10.20 13 388 2.4E-53 T 28-03-2018 MKLM6_RS13980 e247c873bc553b73fe6be6a46c0492ff 814 Gene3D G3DSA:2.170.130.10 51 170 8.3E-13 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS13980 e247c873bc553b73fe6be6a46c0492ff 814 SUPERFAMILY SSF56935 633 814 8.06E-72 T 28-03-2018 MKLM6_RS13980 e247c873bc553b73fe6be6a46c0492ff 814 SUPERFAMILY SSF56935 62 458 8.06E-72 T 28-03-2018 MKLM6_RS13980 e247c873bc553b73fe6be6a46c0492ff 814 SUPERFAMILY SSF56935 504 603 8.06E-72 T 28-03-2018 MKLM6_RS13980 e247c873bc553b73fe6be6a46c0492ff 814 Pfam PF07715 TonB-dependent Receptor Plug Domain 88 178 1.4E-11 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS13980 e247c873bc553b73fe6be6a46c0492ff 814 Gene3D G3DSA:2.40.170.20 171 814 2.8E-38 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS11590 27e4f118ab750e0e0677f5484cd8fd16 393 Gene3D G3DSA:3.90.1150.10 5 254 1.4E-37 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS11590 27e4f118ab750e0e0677f5484cd8fd16 393 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 237 250 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 MKLM6_RS11590 27e4f118ab750e0e0677f5484cd8fd16 393 SUPERFAMILY SSF53383 4 393 3.59E-114 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS11590 27e4f118ab750e0e0677f5484cd8fd16 393 Pfam PF00155 Aminotransferase class I and II 33 389 7.1E-69 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MKLM6_RS11590 27e4f118ab750e0e0677f5484cd8fd16 393 Gene3D G3DSA:3.90.1150.10 255 393 1.6E-37 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS16780 f7686576f4c8cdbae7e191890e0c9c84 615 Gene3D G3DSA:3.40.190.10 251 359 4.1E-19 T 28-03-2018 MKLM6_RS16780 f7686576f4c8cdbae7e191890e0c9c84 615 Gene3D G3DSA:3.10.105.10 360 575 2.0E-53 T 28-03-2018 MKLM6_RS16780 f7686576f4c8cdbae7e191890e0c9c84 615 SUPERFAMILY SSF53850 98 595 5.16E-122 T 28-03-2018 MKLM6_RS16780 f7686576f4c8cdbae7e191890e0c9c84 615 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 140 511 1.2E-78 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain MKLM6_RS16780 f7686576f4c8cdbae7e191890e0c9c84 615 PIRSF PIRSF002741 50 599 2.1E-114 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MKLM6_RS16780 f7686576f4c8cdbae7e191890e0c9c84 615 Gene3D G3DSA:3.90.76.10 105 250 3.8E-39 T 28-03-2018 MKLM6_RS12975 e837d487b8916d680020091d45e957a4 69 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 5 63 1.5E-10 T 28-03-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system MKLM6_RS12975 e837d487b8916d680020091d45e957a4 69 SUPERFAMILY SSF143100 1 64 4.19E-20 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like MKLM6_RS12975 e837d487b8916d680020091d45e957a4 69 Gene3D G3DSA:3.30.2390.10 2 64 1.0E-19 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like MKLM6_RS06790 d1674f951b5767694a77cf4eaf67f3cf 500 Pfam PF02653 Branched-chain amino acid transport system / permease component 211 482 6.5E-55 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 MKLM6_RS06790 d1674f951b5767694a77cf4eaf67f3cf 500 Gene3D G3DSA:1.25.40.70 136 191 0.064 T 28-03-2018 MKLM6_RS06790 d1674f951b5767694a77cf4eaf67f3cf 500 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 209 496 3.7E-128 T 28-03-2018 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type MKLM6_RS06790 d1674f951b5767694a77cf4eaf67f3cf 500 Gene3D G3DSA:1.25.10.20 59 135 4.7E-4 T 28-03-2018 MKLM6_RS06790 d1674f951b5767694a77cf4eaf67f3cf 500 SUPERFAMILY SSF48371 88 193 1.73E-7 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 MKLM6_RS06790 d1674f951b5767694a77cf4eaf67f3cf 500 Gene3D G3DSA:1.10.3470.10 192 487 1.0E-54 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like MKLM6_RS19060 a42b95558854ef72512c90d194c97366 341 Gene3D G3DSA:1.10.3290.10 13 257 1.6E-55 T 28-03-2018 IPR003812 Fido domain MKLM6_RS19060 a42b95558854ef72512c90d194c97366 341 Pfam PF02661 Fic/DOC family 100 197 2.1E-22 T 28-03-2018 IPR003812 Fido domain MKLM6_RS19060 a42b95558854ef72512c90d194c97366 341 SUPERFAMILY SSF140931 79 249 2.09E-44 T 28-03-2018 IPR003812 Fido domain MKLM6_RS13355 8a64ee33a622cd2f595007723d98719c 234 SUPERFAMILY SSF144091 9 222 8.76E-43 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MKLM6_RS13355 8a64ee33a622cd2f595007723d98719c 234 Pfam PF01694 Rhomboid family 67 223 6.6E-37 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MKLM6_RS13355 8a64ee33a622cd2f595007723d98719c 234 Gene3D G3DSA:1.20.1540.10 11 223 1.2E-46 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MKLM6_RS10600 09905716992fbeedc66ac78bac04d60a 289 SUPERFAMILY SSF109604 14 268 2.86E-45 T 28-03-2018 MKLM6_RS10600 09905716992fbeedc66ac78bac04d60a 289 Pfam PF08668 HDOD domain 18 212 1.1E-40 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD MKLM6_RS10600 09905716992fbeedc66ac78bac04d60a 289 Gene3D G3DSA:1.10.3210.10 6 270 1.2E-26 T 28-03-2018 MKLM6_RS00685 bf117f3df251eba7db24ebaa4cb7c5da 441 Gene3D G3DSA:3.30.565.10 222 436 6.9E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS00685 bf117f3df251eba7db24ebaa4cb7c5da 441 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 335 437 2.1E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS00685 bf117f3df251eba7db24ebaa4cb7c5da 441 Pfam PF07694 5TMR of 5TMR-LYT 41 223 6.9E-30 T 28-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 MKLM6_RS00685 bf117f3df251eba7db24ebaa4cb7c5da 441 SUPERFAMILY SSF55874 300 436 4.32E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS00685 bf117f3df251eba7db24ebaa4cb7c5da 441 Pfam PF06580 Histidine kinase 236 314 2.1E-21 T 28-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 MKLM6_RS01350 0dace67b1006d0b9c350cf53b1df9cbb 441 SMART SM00387 335 441 1.2E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS01350 0dace67b1006d0b9c350cf53b1df9cbb 441 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 336 439 2.4E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS01350 0dace67b1006d0b9c350cf53b1df9cbb 441 Gene3D G3DSA:3.30.565.10 201 440 8.7E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS01350 0dace67b1006d0b9c350cf53b1df9cbb 441 SUPERFAMILY SSF55874 314 439 1.83E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS09900 cc251f702540f9d2b21bc8650d153044 266 SMART SM00470 8 105 3.1E-7 T 28-03-2018 IPR003115 ParB/Sulfiredoxin MKLM6_RS09900 cc251f702540f9d2b21bc8650d153044 266 SUPERFAMILY SSF109709 104 179 2.09E-8 T 28-03-2018 MKLM6_RS09900 cc251f702540f9d2b21bc8650d153044 266 SUPERFAMILY SSF110849 6 97 2.44E-14 T 28-03-2018 IPR003115 ParB/Sulfiredoxin MKLM6_RS09900 cc251f702540f9d2b21bc8650d153044 266 Pfam PF02195 ParB-like nuclease domain 10 104 1.6E-10 T 28-03-2018 IPR003115 ParB/Sulfiredoxin MKLM6_RS09900 cc251f702540f9d2b21bc8650d153044 266 Gene3D G3DSA:3.90.1530.10 2 110 1.6E-14 T 28-03-2018 MKLM6_RS11080 a02298172f327d9c34b4642ee01f149c 444 SUPERFAMILY SSF56954 2 421 5.49E-90 T 28-03-2018 MKLM6_RS11080 a02298172f327d9c34b4642ee01f149c 444 Pfam PF02321 Outer membrane efflux protein 24 211 8.6E-28 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS11080 a02298172f327d9c34b4642ee01f149c 444 Pfam PF02321 Outer membrane efflux protein 237 417 2.4E-30 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS11080 a02298172f327d9c34b4642ee01f149c 444 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 20 433 2.3E-104 T 28-03-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 MKLM6_RS11080 a02298172f327d9c34b4642ee01f149c 444 Gene3D G3DSA:1.20.1600.10 18 424 1.5E-74 T 28-03-2018 MKLM6_RS01005 4af1ff168e486686fbe01b7a368c1cae 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 4.1E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS01005 4af1ff168e486686fbe01b7a368c1cae 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 4.1E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS01005 4af1ff168e486686fbe01b7a368c1cae 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 4.1E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS01005 4af1ff168e486686fbe01b7a368c1cae 85 Pfam PF01016 Ribosomal L27 protein 2 82 4.3E-39 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS01005 4af1ff168e486686fbe01b7a368c1cae 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 82 1.3E-41 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS01005 4af1ff168e486686fbe01b7a368c1cae 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 28-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS01005 4af1ff168e486686fbe01b7a368c1cae 85 SUPERFAMILY SSF110324 2 80 8.37E-34 T 28-03-2018 MKLM6_RS01005 4af1ff168e486686fbe01b7a368c1cae 85 Gene3D G3DSA:2.40.50.100 20 85 2.2E-31 T 28-03-2018 MKLM6_RS01005 4af1ff168e486686fbe01b7a368c1cae 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 69 1.0E-13 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS01005 4af1ff168e486686fbe01b7a368c1cae 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 29.473 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS05105 d597f8f9eec7a6d4eb1df02a409d258a 209 SUPERFAMILY SSF53448 6 190 4.51E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS05105 d597f8f9eec7a6d4eb1df02a409d258a 209 Gene3D G3DSA:3.90.550.10 1 195 4.3E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS05105 d597f8f9eec7a6d4eb1df02a409d258a 209 Pfam PF12804 MobA-like NTP transferase domain 9 167 2.7E-34 T 28-03-2018 IPR025877 MobA-like NTP transferase MKLM6_RS05105 d597f8f9eec7a6d4eb1df02a409d258a 209 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 8 189 2.6E-64 T 28-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 MKLM6_RS05105 d597f8f9eec7a6d4eb1df02a409d258a 209 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 5 192 27.472 T 28-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 MKLM6_RS20005 18ec71a6a61e0066406f7c018d3d4551 80 Gene3D G3DSA:3.30.450.20 3 77 1.0E-5 T 28-03-2018 MKLM6_RS04415 36ce79eec002f749177e4b8840af4b5e 436 SMART SM01091 353 436 1.6E-22 T 28-03-2018 IPR005170 Transporter-associated domain MKLM6_RS04415 36ce79eec002f749177e4b8840af4b5e 436 Pfam PF01595 Domain of unknown function DUF21 10 199 3.6E-46 T 28-03-2018 IPR002550 Domain of unknown function DUF21 MKLM6_RS04415 36ce79eec002f749177e4b8840af4b5e 436 SUPERFAMILY SSF56176 351 434 1.17E-17 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MKLM6_RS04415 36ce79eec002f749177e4b8840af4b5e 436 Gene3D G3DSA:3.10.580.10 199 348 5.7E-25 T 28-03-2018 MKLM6_RS04415 36ce79eec002f749177e4b8840af4b5e 436 Pfam PF03471 Transporter associated domain 354 434 7.5E-17 T 28-03-2018 IPR005170 Transporter-associated domain MKLM6_RS04415 36ce79eec002f749177e4b8840af4b5e 436 SUPERFAMILY SSF54631 210 347 3.79E-19 T 28-03-2018 MKLM6_RS04415 36ce79eec002f749177e4b8840af4b5e 436 Gene3D G3DSA:3.30.465.10 349 434 4.8E-18 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MKLM6_RS07855 06dcc5dbc82050c39e0e3d68921ccbd9 279 Pfam PF12973 ChrR Cupin-like domain 193 274 2.1E-9 T 28-03-2018 IPR025979 ChrR-like cupin domain MKLM6_RS07855 06dcc5dbc82050c39e0e3d68921ccbd9 279 Gene3D G3DSA:2.60.120.10 23 166 4.8E-10 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS07855 06dcc5dbc82050c39e0e3d68921ccbd9 279 Gene3D G3DSA:2.60.120.10 175 279 3.1E-13 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS07855 06dcc5dbc82050c39e0e3d68921ccbd9 279 SUPERFAMILY SSF51182 188 273 5.57E-16 T 28-03-2018 IPR011051 RmlC-like cupin domain MKLM6_RS07855 06dcc5dbc82050c39e0e3d68921ccbd9 279 SUPERFAMILY SSF51182 59 152 1.38E-13 T 28-03-2018 IPR011051 RmlC-like cupin domain MKLM6_RS06985 6fd4337ab781a3758380879c32a34768 741 SUPERFAMILY SSF74863 23 141 7.85E-32 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain MKLM6_RS06985 6fd4337ab781a3758380879c32a34768 741 Pfam PF11412 Disulphide bond corrector protein DsbC 24 140 1.3E-29 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain MKLM6_RS06985 6fd4337ab781a3758380879c32a34768 741 Pfam PF11412 Disulphide bond corrector protein DsbC 173 290 1.4E-33 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain MKLM6_RS06985 6fd4337ab781a3758380879c32a34768 741 Pfam PF13899 Thioredoxin-like 631 713 5.7E-11 T 28-03-2018 MKLM6_RS06985 6fd4337ab781a3758380879c32a34768 741 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 332 535 1.1E-17 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 MKLM6_RS06985 6fd4337ab781a3758380879c32a34768 741 Hamap MF_00399 Thiol:disulfide interchange protein DsbD [dsbD]. 133 741 34.843 T 28-03-2018 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 MKLM6_RS06985 6fd4337ab781a3758380879c32a34768 741 SUPERFAMILY SSF74863 171 291 7.19E-34 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain MKLM6_RS06985 6fd4337ab781a3758380879c32a34768 741 Gene3D G3DSA:3.40.30.10 618 741 7.8E-13 T 28-03-2018 MKLM6_RS06985 6fd4337ab781a3758380879c32a34768 741 Gene3D G3DSA:2.60.40.1250 20 149 3.3E-35 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain MKLM6_RS06985 6fd4337ab781a3758380879c32a34768 741 Gene3D G3DSA:2.60.40.1250 171 298 3.0E-35 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain MKLM6_RS06985 6fd4337ab781a3758380879c32a34768 741 SUPERFAMILY SSF52833 638 740 4.37E-19 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS02515 e0368e09f0ef04e1ff18e5afe2730e09 178 Pfam PF04170 NlpE N-terminal domain 69 157 3.2E-19 T 28-03-2018 IPR007298 Copper resistance lipoprotein NlpE MKLM6_RS01585 8e612c91988a8286c92e96a8d8668283 128 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 5 109 31.843 T 28-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MKLM6_RS01585 8e612c91988a8286c92e96a8d8668283 128 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 54 108 1.0E-19 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MKLM6_RS01585 8e612c91988a8286c92e96a8d8668283 128 SUPERFAMILY SSF141734 3 117 5.62E-48 T 28-03-2018 MKLM6_RS01585 8e612c91988a8286c92e96a8d8668283 128 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 31 105 1.4E-33 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MKLM6_RS12435 2208eea0a396f33a602bfd3ddcb9966a 447 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 9 356 1.8E-137 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 MKLM6_RS12435 2208eea0a396f33a602bfd3ddcb9966a 447 Pfam PF13742 OB-fold nucleic acid binding domain 8 100 4.4E-30 T 28-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 MKLM6_RS12435 2208eea0a396f33a602bfd3ddcb9966a 447 Pfam PF02601 Exonuclease VII, large subunit 124 438 7.1E-102 T 28-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 MKLM6_RS12435 2208eea0a396f33a602bfd3ddcb9966a 447 Gene3D G3DSA:2.40.50.140 1 103 2.4E-8 T 28-03-2018 MKLM6_RS12435 2208eea0a396f33a602bfd3ddcb9966a 447 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 5 442 30.76 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 MKLM6_RS12435 2208eea0a396f33a602bfd3ddcb9966a 447 Gene3D G3DSA:3.90.226.10 175 406 0.0013 T 28-03-2018 MKLM6_RS16120 249fefb53744af81f744b4d8e109d0d4 57 ProSitePatterns PS00202 Rubredoxin signature. 36 46 - T 28-03-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 MKLM6_RS16120 249fefb53744af81f744b4d8e109d0d4 57 Gene3D G3DSA:2.20.25.10 1 18 0.019 T 28-03-2018 MKLM6_RS16120 249fefb53744af81f744b4d8e109d0d4 57 Gene3D G3DSA:2.20.28.10 19 56 3.2E-25 T 28-03-2018 MKLM6_RS16120 249fefb53744af81f744b4d8e109d0d4 57 PRINTS PR00163 Rubredoxin signature 36 52 7.3E-10 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 MKLM6_RS16120 249fefb53744af81f744b4d8e109d0d4 57 PRINTS PR00163 Rubredoxin signature 6 22 7.3E-10 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 MKLM6_RS16120 249fefb53744af81f744b4d8e109d0d4 57 Pfam PF00301 Rubredoxin 6 52 1.3E-23 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 MKLM6_RS16120 249fefb53744af81f744b4d8e109d0d4 57 PIRSF PIRSF000071 3 57 6.9E-25 T 28-03-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 MKLM6_RS16120 249fefb53744af81f744b4d8e109d0d4 57 SUPERFAMILY SSF57802 3 55 6.56E-23 T 28-03-2018 MKLM6_RS21060 67a6c806706af9615be4e4cdb03500a5 283 Pfam PF02569 Pantoate-beta-alanine ligase 3 276 9.6E-101 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MKLM6_RS21060 67a6c806706af9615be4e4cdb03500a5 283 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 276 6.6E-94 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MKLM6_RS21060 67a6c806706af9615be4e4cdb03500a5 283 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 26 76 3.2E-8 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MKLM6_RS21060 67a6c806706af9615be4e4cdb03500a5 283 SUPERFAMILY SSF52374 1 279 3.1E-104 T 28-03-2018 MKLM6_RS21060 67a6c806706af9615be4e4cdb03500a5 283 Hamap MF_00158 Pantothenate synthetase [panC]. 2 278 39.196 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MKLM6_RS21060 67a6c806706af9615be4e4cdb03500a5 283 Gene3D G3DSA:3.40.50.620 1 174 3.9E-74 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS21060 67a6c806706af9615be4e4cdb03500a5 283 Gene3D G3DSA:3.30.1300.10 175 282 9.4E-33 T 28-03-2018 MKLM6_RS01590 372504b637bcee21e2eed91372e383b6 257 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 3 256 1.1E-115 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 MKLM6_RS01590 372504b637bcee21e2eed91372e383b6 257 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 256 49.1 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 MKLM6_RS01590 372504b637bcee21e2eed91372e383b6 257 Gene3D G3DSA:3.20.20.70 5 252 3.3E-70 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS01590 372504b637bcee21e2eed91372e383b6 257 SUPERFAMILY SSF51366 3 256 2.67E-85 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MKLM6_RS01590 372504b637bcee21e2eed91372e383b6 257 Pfam PF00977 Histidine biosynthesis protein 6 240 6.7E-92 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 MKLM6_RS12130 14529f356562367afe2d2859159d2587 298 Gene3D G3DSA:3.20.20.450 64 290 1.6E-13 T 28-03-2018 IPR001633 EAL domain MKLM6_RS12130 14529f356562367afe2d2859159d2587 298 SUPERFAMILY SSF141868 93 277 4.45E-7 T 28-03-2018 IPR001633 EAL domain MKLM6_RS20295 26390fea8f485ddb3b959549182f93b8 176 PIRSF PIRSF028301 1 174 4.7E-60 T 28-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 MKLM6_RS20295 26390fea8f485ddb3b959549182f93b8 176 Pfam PF05591 Type VI secretion system, VipA, VC_A0107 or Hcp2 10 160 1.9E-57 T 28-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 MKLM6_RS20295 26390fea8f485ddb3b959549182f93b8 176 TIGRFAM TIGR03358 VI_chp_5: type VI secretion protein, VC_A0107 family 6 162 3.8E-56 T 28-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 MKLM6_RS10945 f6d03d33f4079f21b777afa81384365f 240 SUPERFAMILY SSF52540 6 226 3.55E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS10945 f6d03d33f4079f21b777afa81384365f 240 Gene3D G3DSA:3.40.50.300 3 237 1.1E-53 T 28-03-2018 MKLM6_RS10945 f6d03d33f4079f21b777afa81384365f 240 Pfam PF00005 ABC transporter 23 165 4.6E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS10945 f6d03d33f4079f21b777afa81384365f 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS10945 f6d03d33f4079f21b777afa81384365f 240 SMART SM00382 31 213 2.9E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS14340 288a5d0e23c21dc1c730582480a0ac0c 178 Gene3D G3DSA:3.10.490.10 45 173 1.5E-26 T 28-03-2018 MKLM6_RS14340 288a5d0e23c21dc1c730582480a0ac0c 178 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 49 170 1.7E-21 T 28-03-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like MKLM6_RS14340 288a5d0e23c21dc1c730582480a0ac0c 178 SUPERFAMILY SSF110857 48 171 1.02E-23 T 28-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like MKLM6_RS13705 14064dec0e698cac5d40275fa74112cb 148 Gene3D G3DSA:3.40.5.10 1 49 1.2E-21 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS13705 14064dec0e698cac5d40275fa74112cb 148 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 5.8E-21 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS13705 14064dec0e698cac5d40275fa74112cb 148 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 147 1.8E-26 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal MKLM6_RS13705 14064dec0e698cac5d40275fa74112cb 148 SUPERFAMILY SSF55653 60 148 1.31E-25 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal MKLM6_RS13705 14064dec0e698cac5d40275fa74112cb 148 Gene3D G3DSA:3.10.430.100 63 147 1.0E-26 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal MKLM6_RS13705 14064dec0e698cac5d40275fa74112cb 148 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS13705 14064dec0e698cac5d40275fa74112cb 148 SUPERFAMILY SSF55658 1 57 2.62E-17 T 28-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal MKLM6_RS13705 14064dec0e698cac5d40275fa74112cb 148 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 25.608 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS13705 14064dec0e698cac5d40275fa74112cb 148 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 148 2.7E-51 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 MKLM6_RS15345 8fa53ec21c7e29f90d7b2229fae3a1bf 305 Gene3D G3DSA:3.40.50.300 115 303 1.6E-13 T 28-03-2018 MKLM6_RS15345 8fa53ec21c7e29f90d7b2229fae3a1bf 305 TIGRFAM TIGR04352 HprK_rel_A: HprK-related kinase A 21 300 8.6E-106 T 28-03-2018 IPR027600 HprK-related kinase A MKLM6_RS15345 8fa53ec21c7e29f90d7b2229fae3a1bf 305 SUPERFAMILY SSF53795 116 184 1.04E-11 T 28-03-2018 MKLM6_RS12360 e2e1a156b56fffe826cc97ea60e1f288 117 Pfam PF07110 EthD domain 19 93 8.0E-7 T 28-03-2018 IPR009799 EthD domain MKLM6_RS12360 e2e1a156b56fffe826cc97ea60e1f288 117 SUPERFAMILY SSF54909 1 104 7.24E-18 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel MKLM6_RS12360 e2e1a156b56fffe826cc97ea60e1f288 117 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 1 103 1.4E-22 T 28-03-2018 IPR009799 EthD domain MKLM6_RS12360 e2e1a156b56fffe826cc97ea60e1f288 117 Gene3D G3DSA:3.30.70.100 3 102 4.6E-15 T 28-03-2018 MKLM6_RS17135 d5854f66698c0b6631b3ba1b6f1c9453 373 Gene3D G3DSA:3.40.1710.10 42 192 6.9E-22 T 28-03-2018 MKLM6_RS17135 d5854f66698c0b6631b3ba1b6f1c9453 373 Pfam PF12698 ABC-2 family transporter protein 26 366 4.9E-45 T 28-03-2018 MKLM6_RS14060 65cee04bfabdbf04bf740aef9749e7f3 278 SUPERFAMILY SSF109604 16 268 1.04E-56 T 28-03-2018 MKLM6_RS14060 65cee04bfabdbf04bf740aef9749e7f3 278 Gene3D G3DSA:1.10.3210.10 1 269 4.8E-43 T 28-03-2018 MKLM6_RS14060 65cee04bfabdbf04bf740aef9749e7f3 278 TIGRFAM TIGR00277 HDIG: HDIG domain 115 212 2.7E-10 T 28-03-2018 IPR006675 HDIG domain MKLM6_RS14060 65cee04bfabdbf04bf740aef9749e7f3 278 SMART SM00471 112 243 3.7E-5 T 28-03-2018 IPR003607 HD/PDEase domain MKLM6_RS14060 65cee04bfabdbf04bf740aef9749e7f3 278 Pfam PF08668 HDOD domain 21 213 5.2E-47 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD MKLM6_RS08630 1b43ee2906dfe4093cb7979b11855635 120 SUPERFAMILY SSF53146 4 111 2.22E-27 T 28-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis MKLM6_RS08630 1b43ee2906dfe4093cb7979b11855635 120 Gene3D G3DSA:3.30.420.130 2 118 6.0E-26 T 28-03-2018 MKLM6_RS08630 1b43ee2906dfe4093cb7979b11855635 120 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 15 109 9.8E-20 T 28-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis MKLM6_RS03670 5866eeee9cb0068d53aacb7cf0aa72b1 205 Gene3D G3DSA:1.10.357.10 62 190 1.4E-16 T 28-03-2018 MKLM6_RS03670 5866eeee9cb0068d53aacb7cf0aa72b1 205 SUPERFAMILY SSF48498 90 185 3.02E-10 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MKLM6_RS03670 5866eeee9cb0068d53aacb7cf0aa72b1 205 SUPERFAMILY SSF46689 13 85 2.21E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS03670 5866eeee9cb0068d53aacb7cf0aa72b1 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 8.1E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MKLM6_RS03670 5866eeee9cb0068d53aacb7cf0aa72b1 205 Gene3D G3DSA:1.10.10.60 7 61 1.8E-17 T 28-03-2018 MKLM6_RS03670 5866eeee9cb0068d53aacb7cf0aa72b1 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MKLM6_RS03670 5866eeee9cb0068d53aacb7cf0aa72b1 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MKLM6_RS07455 e0654dca9434db34270b04e2780a9da0 408 Gene3D G3DSA:1.10.443.10 211 385 5.9E-39 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS07455 e0654dca9434db34270b04e2780a9da0 408 Pfam PF13356 Arm DNA-binding domain 8 96 8.1E-16 T 28-03-2018 IPR025166 Integrase, DNA-binding domain MKLM6_RS07455 e0654dca9434db34270b04e2780a9da0 408 SUPERFAMILY SSF56349 103 377 4.41E-59 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS07455 e0654dca9434db34270b04e2780a9da0 408 Pfam PF00589 Phage integrase family 210 368 6.6E-23 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS07455 e0654dca9434db34270b04e2780a9da0 408 Gene3D G3DSA:1.10.150.130 98 210 3.9E-16 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal MKLM6_RS13375 edbc077997a0d88876e3bf456e4f983a 689 Pfam PF00593 TonB dependent receptor 197 687 9.1E-36 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS13375 edbc077997a0d88876e3bf456e4f983a 689 Gene3D G3DSA:2.40.170.20 178 689 1.1E-57 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS13375 edbc077997a0d88876e3bf456e4f983a 689 SUPERFAMILY SSF56935 57 689 8.93E-97 T 28-03-2018 MKLM6_RS13375 edbc077997a0d88876e3bf456e4f983a 689 Pfam PF07715 TonB-dependent Receptor Plug Domain 66 174 3.9E-22 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS13375 edbc077997a0d88876e3bf456e4f983a 689 Gene3D G3DSA:2.170.130.10 63 177 3.3E-29 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS14310 647a610eb81f50dc1388ea16aaa6ddc8 293 SUPERFAMILY SSF51658 42 220 3.39E-11 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MKLM6_RS14310 647a610eb81f50dc1388ea16aaa6ddc8 293 Gene3D G3DSA:3.20.20.150 17 293 5.3E-82 T 28-03-2018 MKLM6_RS14310 647a610eb81f50dc1388ea16aaa6ddc8 293 Hamap MF_00697 UPF0276 protein . 21 293 43.782 T 28-03-2018 IPR007801 Uncharacterised protein family UPF0276 MKLM6_RS14310 647a610eb81f50dc1388ea16aaa6ddc8 293 Pfam PF05114 Protein of unknown function (DUF692) 21 285 6.4E-98 T 28-03-2018 IPR007801 Uncharacterised protein family UPF0276 MKLM6_RS21750 40e4d4ba837ae0f300e43a19448c3bf1 109 Gene3D G3DSA:3.30.460.10 8 109 3.5E-19 T 28-03-2018 MKLM6_RS21750 40e4d4ba837ae0f300e43a19448c3bf1 109 SUPERFAMILY SSF81301 20 102 6.27E-17 T 28-03-2018 MKLM6_RS21750 40e4d4ba837ae0f300e43a19448c3bf1 109 Pfam PF01909 Nucleotidyltransferase domain 23 97 1.6E-8 T 28-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 MKLM6_RS15805 fb5976856194510e334e40a757b6e15f 290 Gene3D G3DSA:3.40.50.150 113 275 9.5E-6 T 28-03-2018 MKLM6_RS15805 fb5976856194510e334e40a757b6e15f 290 Pfam PF13578 Methyltransferase domain 129 254 1.5E-10 T 28-03-2018 MKLM6_RS15805 fb5976856194510e334e40a757b6e15f 290 SUPERFAMILY SSF53335 120 262 8.15E-5 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS15015 f55df45e59ed092bf6d41f887ceb03ca 160 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 1 153 2.7E-61 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 MKLM6_RS15015 f55df45e59ed092bf6d41f887ceb03ca 160 Gene3D G3DSA:3.40.1280.10 1 156 4.5E-38 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MKLM6_RS15015 f55df45e59ed092bf6d41f887ceb03ca 160 Pfam PF00588 SpoU rRNA Methylase family 2 142 1.1E-33 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MKLM6_RS15015 f55df45e59ed092bf6d41f887ceb03ca 160 PIRSF PIRSF029256 1 154 3.5E-64 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 MKLM6_RS15015 f55df45e59ed092bf6d41f887ceb03ca 160 SUPERFAMILY SSF75217 2 152 7.85E-46 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases MKLM6_RS15015 f55df45e59ed092bf6d41f887ceb03ca 160 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 151 33.884 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 MKLM6_RS20205 e756304ed57be7354e5b0909c10e8be6 77 Pfam PF06945 Protein of unknown function (DUF1289) 14 60 1.5E-18 T 28-03-2018 IPR010710 Protein of unknown function DUF1289 MKLM6_RS21775 e4d1c04d71413e0f64af2a2667777ab7 234 Pfam PF01569 PAP2 superfamily 95 217 3.0E-19 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MKLM6_RS21775 e4d1c04d71413e0f64af2a2667777ab7 234 SMART SM00014 94 214 0.0028 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MKLM6_RS21775 e4d1c04d71413e0f64af2a2667777ab7 234 Gene3D G3DSA:1.20.144.10 4 228 7.5E-17 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MKLM6_RS21775 e4d1c04d71413e0f64af2a2667777ab7 234 SUPERFAMILY SSF48317 10 220 1.18E-21 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MKLM6_RS01750 5992922913184ae99c70ac81f744bc76 650 Pfam PF13559 Domain of unknown function (DUF4129) 578 642 3.6E-10 T 28-03-2018 IPR025403 Domain of unknown function DUF4129 MKLM6_RS01750 5992922913184ae99c70ac81f744bc76 650 SUPERFAMILY SSF54001 271 596 1.07E-56 T 28-03-2018 MKLM6_RS01750 5992922913184ae99c70ac81f744bc76 650 Gene3D G3DSA:3.90.260.10 333 540 5.5E-21 T 28-03-2018 IPR002931 Transglutaminase-like MKLM6_RS01750 5992922913184ae99c70ac81f744bc76 650 Pfam PF11992 Domain of unknown function (DUF3488) 10 321 5.5E-93 T 28-03-2018 IPR021878 Protein of unknown function DUF3488 MKLM6_RS01750 5992922913184ae99c70ac81f744bc76 650 SMART SM00460 396 467 2.5E-21 T 28-03-2018 IPR002931 Transglutaminase-like MKLM6_RS01750 5992922913184ae99c70ac81f744bc76 650 Pfam PF01841 Transglutaminase-like superfamily 353 465 1.3E-25 T 28-03-2018 IPR002931 Transglutaminase-like MKLM6_RS01515 600496968f968fb8298205569dc2bee5 396 Pfam PF12242 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2 79 2.7E-37 T 28-03-2018 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MKLM6_RS01515 600496968f968fb8298205569dc2bee5 396 Pfam PF12241 Trans-2-enoyl-CoA reductase catalytic region 82 317 7.6E-111 T 28-03-2018 IPR024910 Trans-2-enoyl-CoA reductase catalytic domain, putative KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MKLM6_RS01515 600496968f968fb8298205569dc2bee5 396 Pfam PF07055 Enoyl reductase FAD binding domain 323 386 4.0E-29 T 28-03-2018 IPR024906 Enoyl reductase FAD binding domain KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MKLM6_RS01515 600496968f968fb8298205569dc2bee5 396 Hamap MF_01838 Trans-2-enoyl-CoA reductase [NADH] [fabV]. 1 392 54.621 T 28-03-2018 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MKLM6_RS15825 a55a007bf826af2d8af767810e474fe4 235 Pfam PF02585 GlcNAc-PI de-N-acetylase 9 135 6.4E-19 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 MKLM6_RS15825 a55a007bf826af2d8af767810e474fe4 235 SUPERFAMILY SSF102588 9 229 1.2E-42 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 MKLM6_RS15825 a55a007bf826af2d8af767810e474fe4 235 Gene3D G3DSA:3.40.50.10320 2 235 3.6E-49 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 MKLM6_RS16985 410c9a0f7c24d31ac18fdd2c00335b30 383 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 38 283 1.2E-16 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MKLM6_RS16985 410c9a0f7c24d31ac18fdd2c00335b30 383 Gene3D G3DSA:2.40.50.100 166 338 3.2E-4 T 28-03-2018 MKLM6_RS16985 410c9a0f7c24d31ac18fdd2c00335b30 383 SUPERFAMILY SSF111369 41 283 1.12E-24 T 28-03-2018 MKLM6_RS16985 410c9a0f7c24d31ac18fdd2c00335b30 383 Gene3D G3DSA:2.40.50.100 51 115 4.5E-16 T 28-03-2018 MKLM6_RS16985 410c9a0f7c24d31ac18fdd2c00335b30 383 Gene3D G3DSA:1.10.287.470 116 165 2.6E-7 T 28-03-2018 MKLM6_RS16985 410c9a0f7c24d31ac18fdd2c00335b30 383 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 29 357 1.7E-48 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MKLM6_RS00505 781e16d8a171dbb84d4629d088719226 677 Gene3D G3DSA:2.40.170.20 177 677 1.4E-61 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS00505 781e16d8a171dbb84d4629d088719226 677 Pfam PF00593 TonB dependent receptor 260 675 5.6E-37 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS00505 781e16d8a171dbb84d4629d088719226 677 SUPERFAMILY SSF56935 49 677 3.0E-99 T 28-03-2018 MKLM6_RS00505 781e16d8a171dbb84d4629d088719226 677 Pfam PF07715 TonB-dependent Receptor Plug Domain 60 169 4.6E-20 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS00505 781e16d8a171dbb84d4629d088719226 677 Gene3D G3DSA:2.170.130.10 38 176 3.0E-27 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS15320 c3e60f349691d4b92387142864d66cb0 586 Gene3D G3DSA:3.40.50.620 180 585 1.3E-62 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS15320 c3e60f349691d4b92387142864d66cb0 586 Pfam PF00733 Asparagine synthase 197 580 4.4E-75 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 MKLM6_RS15320 c3e60f349691d4b92387142864d66cb0 586 Gene3D G3DSA:3.60.20.10 46 179 6.8E-12 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MKLM6_RS15320 c3e60f349691d4b92387142864d66cb0 586 SUPERFAMILY SSF56235 85 182 7.46E-13 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MKLM6_RS15320 c3e60f349691d4b92387142864d66cb0 586 PIRSF PIRSF001589 61 582 3.4E-79 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MKLM6_RS15320 c3e60f349691d4b92387142864d66cb0 586 SUPERFAMILY SSF52402 187 339 1.49E-62 T 28-03-2018 MKLM6_RS15320 c3e60f349691d4b92387142864d66cb0 586 SUPERFAMILY SSF52402 436 575 1.49E-62 T 28-03-2018 MKLM6_RS07980 373743b02796571d214e5c2b93271618 396 Pfam PF06282 Protein of unknown function (DUF1036) 20 134 1.8E-21 T 28-03-2018 IPR009380 Protein of unknown function DUF1036 MKLM6_RS05505 764acf2c5ecd6905a5ce5baa1d0de18f 680 Gene3D G3DSA:2.170.130.10 25 174 4.4E-30 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS05505 764acf2c5ecd6905a5ce5baa1d0de18f 680 Pfam PF00593 TonB dependent receptor 214 659 5.3E-30 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS05505 764acf2c5ecd6905a5ce5baa1d0de18f 680 Gene3D G3DSA:2.40.170.20 175 680 9.0E-53 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS05505 764acf2c5ecd6905a5ce5baa1d0de18f 680 Pfam PF07715 TonB-dependent Receptor Plug Domain 59 167 1.4E-23 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS05505 764acf2c5ecd6905a5ce5baa1d0de18f 680 SUPERFAMILY SSF56935 50 680 4.71E-93 T 28-03-2018 MKLM6_RS17025 d45713b264153ff569c52832da01f086 426 SUPERFAMILY SSF52218 267 411 1.83E-35 T 28-03-2018 IPR029039 Flavoprotein-like domain MKLM6_RS17025 d45713b264153ff569c52832da01f086 426 Pfam PF00258 Flavodoxin 271 399 9.6E-10 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MKLM6_RS17025 d45713b264153ff569c52832da01f086 426 Pfam PF00753 Metallo-beta-lactamase superfamily 46 180 4.3E-12 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS17025 d45713b264153ff569c52832da01f086 426 SMART SM00849 46 235 1.2E-31 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS17025 d45713b264153ff569c52832da01f086 426 PIRSF PIRSF005243 14 415 3.7E-124 T 28-03-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 MKLM6_RS17025 d45713b264153ff569c52832da01f086 426 Gene3D G3DSA:3.60.15.10 9 263 1.5E-41 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS17025 d45713b264153ff569c52832da01f086 426 ProSitePatterns PS00201 Flavodoxin signature. 271 287 - T 28-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 MKLM6_RS17025 d45713b264153ff569c52832da01f086 426 Gene3D G3DSA:3.40.50.360 264 421 1.5E-22 T 28-03-2018 IPR029039 Flavoprotein-like domain MKLM6_RS17025 d45713b264153ff569c52832da01f086 426 SUPERFAMILY SSF56281 17 253 5.63E-46 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS06445 1685d031c1ee6b55ab141471a29c1979 218 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 35 127 3.5E-14 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MKLM6_RS06445 1685d031c1ee6b55ab141471a29c1979 218 Gene3D G3DSA:2.30.110.10 26 187 2.9E-19 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MKLM6_RS06445 1685d031c1ee6b55ab141471a29c1979 218 SUPERFAMILY SSF50475 33 133 3.51E-13 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MKLM6_RS14235 1eb419791237cd00b02a927e15aa94bc 109 SUPERFAMILY SSF51182 16 106 4.45E-13 T 28-03-2018 IPR011051 RmlC-like cupin domain MKLM6_RS14235 1eb419791237cd00b02a927e15aa94bc 109 Gene3D G3DSA:2.60.120.10 1 109 1.2E-12 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS11625 6c869e9b3ce12fa98052cfdc81ad54ec 77 SUPERFAMILY SSF50037 8 76 1.37E-20 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal MKLM6_RS11625 6c869e9b3ce12fa98052cfdc81ad54ec 77 Pfam PF04023 FeoA domain 8 75 2.3E-15 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 MKLM6_RS11625 6c869e9b3ce12fa98052cfdc81ad54ec 77 Gene3D G3DSA:2.30.30.90 6 77 5.2E-19 T 28-03-2018 MKLM6_RS11625 6c869e9b3ce12fa98052cfdc81ad54ec 77 SMART SM00899 3 76 6.6E-20 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 MKLM6_RS01200 c96519634bc6de68dce93bddf56d01dc 327 Gene3D G3DSA:3.40.50.720 158 321 2.0E-7 T 28-03-2018 MKLM6_RS01200 c96519634bc6de68dce93bddf56d01dc 327 TIGRFAM TIGR02822 adh_fam_2: zinc-binding alcohol dehydrogenase family protein 11 326 2.8E-102 T 28-03-2018 IPR014187 Alcohol dehydrogenase, zinc-binding type 2 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 MKLM6_RS01200 c96519634bc6de68dce93bddf56d01dc 327 SUPERFAMILY SSF50129 1 160 1.98E-49 T 28-03-2018 IPR011032 GroES-like MKLM6_RS01200 c96519634bc6de68dce93bddf56d01dc 327 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MKLM6_RS01200 c96519634bc6de68dce93bddf56d01dc 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 132 1.1E-32 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MKLM6_RS01200 c96519634bc6de68dce93bddf56d01dc 327 Gene3D G3DSA:3.90.180.10 1 157 3.5E-53 T 28-03-2018 MKLM6_RS01200 c96519634bc6de68dce93bddf56d01dc 327 SUPERFAMILY SSF51735 139 292 1.86E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS04125 996c226a9923b208e7c4a87ac8740431 457 SUPERFAMILY SSF47384 226 283 3.92E-5 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS04125 996c226a9923b208e7c4a87ac8740431 457 Gene3D G3DSA:1.10.287.130 214 307 0.0018 T 28-03-2018 MKLM6_RS04125 996c226a9923b208e7c4a87ac8740431 457 Gene3D G3DSA:3.30.565.10 308 449 7.4E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS04125 996c226a9923b208e7c4a87ac8740431 457 SUPERFAMILY SSF55874 305 444 4.45E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS04125 996c226a9923b208e7c4a87ac8740431 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 391 2.1E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS04125 996c226a9923b208e7c4a87ac8740431 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 424 2.1E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS04125 996c226a9923b208e7c4a87ac8740431 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 443 2.1E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS04125 996c226a9923b208e7c4a87ac8740431 457 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 342 444 9.6E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS04125 996c226a9923b208e7c4a87ac8740431 457 SMART SM00387 340 446 1.1E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS13645 1c55a6d84ea75135f8bca6d650545407 150 Gene3D G3DSA:3.90.79.10 1 144 1.9E-16 T 28-03-2018 MKLM6_RS13645 1c55a6d84ea75135f8bca6d650545407 150 Pfam PF00293 NUDIX domain 18 133 1.6E-11 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MKLM6_RS13645 1c55a6d84ea75135f8bca6d650545407 150 SUPERFAMILY SSF55811 18 149 1.07E-21 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MKLM6_RS13645 1c55a6d84ea75135f8bca6d650545407 150 PIRSF PIRSF037599 1 150 3.6E-55 T 28-03-2018 IPR033715 GDP-mannose mannosyl hydrolase GO:0008727 MKLM6_RS00975 a502e68e4242cab29cdb85534151515b 571 SUPERFAMILY SSF52540 169 569 1.98E-100 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS00975 a502e68e4242cab29cdb85534151515b 571 TIGRFAM TIGR02538 type_IV_pilB: type IV-A pilus assembly ATPase PilB 13 570 3.5E-264 T 28-03-2018 IPR013374 ATPase, type IV, pilus assembly, PilB GO:0005524|GO:0008565|GO:0009297 MKLM6_RS00975 a502e68e4242cab29cdb85534151515b 571 SUPERFAMILY SSF160246 8 145 2.22E-37 T 28-03-2018 MKLM6_RS00975 a502e68e4242cab29cdb85534151515b 571 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 390 404 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 MKLM6_RS00975 a502e68e4242cab29cdb85534151515b 571 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 46 146 2.4E-18 T 28-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 MKLM6_RS00975 a502e68e4242cab29cdb85534151515b 571 Gene3D G3DSA:3.40.50.300 296 571 2.2E-61 T 28-03-2018 MKLM6_RS00975 a502e68e4242cab29cdb85534151515b 571 Gene3D G3DSA:3.30.450.90 158 295 6.2E-46 T 28-03-2018 MKLM6_RS00975 a502e68e4242cab29cdb85534151515b 571 Pfam PF00437 Type II/IV secretion system protein 195 462 3.4E-88 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 MKLM6_RS00870 691e7fda8767d3ba3205517e51f39b76 240 Gene3D G3DSA:1.10.760.10 26 205 4.7E-50 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS00870 691e7fda8767d3ba3205517e51f39b76 240 SUPERFAMILY SSF46626 16 204 4.41E-46 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS00870 691e7fda8767d3ba3205517e51f39b76 240 Pfam PF02167 Cytochrome C1 family 34 239 1.1E-17 T 28-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 MKLM6_RS00870 691e7fda8767d3ba3205517e51f39b76 240 Gene3D G3DSA:1.20.5.100 209 239 9.2E-14 T 28-03-2018 MKLM6_RS15605 96b10b84935c4fe9887c911f876c97a8 393 ProSitePatterns PS01068 OmpA-like domain. 322 366 - T 28-03-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 MKLM6_RS15605 96b10b84935c4fe9887c911f876c97a8 393 Pfam PF00691 OmpA family 289 384 1.7E-24 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS15605 96b10b84935c4fe9887c911f876c97a8 393 PRINTS PR01021 OMPA domain signature 335 351 6.8E-16 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MKLM6_RS15605 96b10b84935c4fe9887c911f876c97a8 393 PRINTS PR01021 OMPA domain signature 320 335 6.8E-16 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MKLM6_RS15605 96b10b84935c4fe9887c911f876c97a8 393 PRINTS PR01021 OMPA domain signature 290 312 6.8E-16 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MKLM6_RS15605 96b10b84935c4fe9887c911f876c97a8 393 Gene3D G3DSA:3.40.50.410 45 243 9.5E-17 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS15605 96b10b84935c4fe9887c911f876c97a8 393 SUPERFAMILY SSF53300 56 240 5.56E-14 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS15605 96b10b84935c4fe9887c911f876c97a8 393 SUPERFAMILY SSF103647 245 295 1.7E-6 T 28-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 MKLM6_RS15605 96b10b84935c4fe9887c911f876c97a8 393 Gene3D G3DSA:3.30.1330.60 262 393 3.1E-39 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS15605 96b10b84935c4fe9887c911f876c97a8 393 SUPERFAMILY SSF103088 284 387 1.44E-37 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS11990 b4ec09449d4d75da13da5a58e1af0c59 286 Gene3D G3DSA:1.10.3210.10 3 278 1.0E-26 T 28-03-2018 MKLM6_RS11990 b4ec09449d4d75da13da5a58e1af0c59 286 Pfam PF08668 HDOD domain 16 216 5.4E-34 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD MKLM6_RS11990 b4ec09449d4d75da13da5a58e1af0c59 286 SUPERFAMILY SSF109604 10 273 6.91E-43 T 28-03-2018 MKLM6_RS01175 976438dbc8041d07c006f547aba4580d 281 Pfam PF01618 MotA/TolQ/ExbB proton channel family 132 232 1.3E-9 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 MKLM6_RS01175 976438dbc8041d07c006f547aba4580d 281 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 202 219 - T 28-03-2018 IPR000540 Flagellar motor protein MotA, conserved site MKLM6_RS01175 976438dbc8041d07c006f547aba4580d 281 TIGRFAM TIGR03818 MotA1: flagellar motor stator protein MotA 1 278 5.1E-102 T 28-03-2018 IPR022522 Flagellar motor stator, MotA MKLM6_RS21390 805878e082696f43fe9a90d357aa28fa 277 Pfam PF02535 ZIP Zinc transporter 96 266 2.6E-34 T 28-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 MKLM6_RS01115 ab2e3cc9da735443771049998b7335ba 241 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 16 232 7.0E-37 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MKLM6_RS01115 ab2e3cc9da735443771049998b7335ba 241 SMART SM00934 16 232 4.4E-68 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MKLM6_RS01115 ab2e3cc9da735443771049998b7335ba 241 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 17 233 2.0E-56 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MKLM6_RS01115 ab2e3cc9da735443771049998b7335ba 241 Gene3D G3DSA:3.20.20.70 13 237 5.4E-49 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS01115 ab2e3cc9da735443771049998b7335ba 241 SUPERFAMILY SSF51366 14 234 9.74E-58 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MKLM6_RS01115 ab2e3cc9da735443771049998b7335ba 241 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 14 237 31.908 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MKLM6_RS01115 ab2e3cc9da735443771049998b7335ba 241 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 69 82 - T 28-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MKLM6_RS20670 f625b568cc5e743072e21af75ae8501d 330 Gene3D G3DSA:1.10.10.60 273 318 2.9E-9 T 28-03-2018 MKLM6_RS20670 f625b568cc5e743072e21af75ae8501d 330 Gene3D G3DSA:1.10.10.60 130 272 0.014 T 28-03-2018 MKLM6_RS20670 f625b568cc5e743072e21af75ae8501d 330 SUPERFAMILY SSF46689 271 318 1.03E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS20670 f625b568cc5e743072e21af75ae8501d 330 SMART SM00342 234 317 1.4E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MKLM6_RS20670 f625b568cc5e743072e21af75ae8501d 330 Pfam PF12833 Helix-turn-helix domain 240 316 2.1E-14 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MKLM6_RS19575 e93bac7848177fdd7931adbe81f53e4f 215 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 104 180 5.3E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MKLM6_RS19575 e93bac7848177fdd7931adbe81f53e4f 215 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 186 1.7E-34 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS19575 e93bac7848177fdd7931adbe81f53e4f 215 Gene3D G3DSA:1.10.150.240 19 76 7.5E-12 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 MKLM6_RS19575 e93bac7848177fdd7931adbe81f53e4f 215 SUPERFAMILY SSF56784 3 215 3.82E-52 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS19575 e93bac7848177fdd7931adbe81f53e4f 215 Gene3D G3DSA:3.40.50.1000 77 215 5.0E-28 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS14065 582985b48d233f66bdd67f9f0d1dda12 632 Gene3D G3DSA:3.30.450.90 204 336 2.5E-41 T 28-03-2018 MKLM6_RS14065 582985b48d233f66bdd67f9f0d1dda12 632 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 113 218 1.8E-15 T 28-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 MKLM6_RS14065 582985b48d233f66bdd67f9f0d1dda12 632 SUPERFAMILY SSF52540 223 611 1.59E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS14065 582985b48d233f66bdd67f9f0d1dda12 632 Gene3D G3DSA:3.40.50.300 337 618 6.6E-46 T 28-03-2018 MKLM6_RS14065 582985b48d233f66bdd67f9f0d1dda12 632 SUPERFAMILY SSF160246 73 210 4.71E-26 T 28-03-2018 MKLM6_RS14065 582985b48d233f66bdd67f9f0d1dda12 632 Pfam PF00437 Type II/IV secretion system protein 236 504 4.0E-67 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 MKLM6_RS14065 582985b48d233f66bdd67f9f0d1dda12 632 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 432 446 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 MKLM6_RS12035 2c8987932d5710139214e243b7e7e5fc 158 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 47 138 5.4E-14 T 28-03-2018 IPR000014 PAS domain MKLM6_RS12035 2c8987932d5710139214e243b7e7e5fc 158 SUPERFAMILY SSF55785 44 139 1.73E-25 T 28-03-2018 IPR000014 PAS domain MKLM6_RS12035 2c8987932d5710139214e243b7e7e5fc 158 Gene3D G3DSA:3.40.50.10600 39 146 6.4E-29 T 28-03-2018 MKLM6_RS12035 2c8987932d5710139214e243b7e7e5fc 158 Pfam PF08447 PAS fold 56 138 2.3E-15 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS19110 421e6872ced105e18d76bd0b00317722 314 Pfam PF01925 Sulfite exporter TauE/SafE 5 247 1.5E-48 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MKLM6_RS20730 6937b10a6f17af9d47790caef9c397a1 194 Gene3D G3DSA:1.10.10.10 6 146 2.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS20730 6937b10a6f17af9d47790caef9c397a1 194 SUPERFAMILY SSF46785 4 137 2.34E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS20730 6937b10a6f17af9d47790caef9c397a1 194 SMART SM00347 23 123 0.0016 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MKLM6_RS20730 6937b10a6f17af9d47790caef9c397a1 194 Pfam PF12802 MarR family 29 88 3.8E-8 T 28-03-2018 MKLM6_RS20940 7beb927db91730e2e3282ebe3e336fc7 842 Pfam PF07660 Secretin and TonB N terminus short domain 67 115 3.3E-8 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MKLM6_RS20940 7beb927db91730e2e3282ebe3e336fc7 842 SUPERFAMILY SSF56935 118 841 9.16E-123 T 28-03-2018 MKLM6_RS20940 7beb927db91730e2e3282ebe3e336fc7 842 Pfam PF00593 TonB dependent receptor 331 840 1.2E-55 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS20940 7beb927db91730e2e3282ebe3e336fc7 842 Gene3D G3DSA:2.170.130.10 118 265 1.7E-25 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS20940 7beb927db91730e2e3282ebe3e336fc7 842 Pfam PF07715 TonB-dependent Receptor Plug Domain 163 257 4.0E-17 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS20940 7beb927db91730e2e3282ebe3e336fc7 842 Gene3D G3DSA:2.40.170.20 271 842 5.8E-78 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS20940 7beb927db91730e2e3282ebe3e336fc7 842 SMART SM00965 65 116 2.1E-14 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MKLM6_RS20940 7beb927db91730e2e3282ebe3e336fc7 842 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 164 840 4.0E-100 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 MKLM6_RS09085 c444693bedda61177dc1a77fa37d4fb9 330 Gene3D G3DSA:3.30.470.20 122 330 5.1E-21 T 28-03-2018 MKLM6_RS09085 c444693bedda61177dc1a77fa37d4fb9 330 SUPERFAMILY SSF56059 105 323 8.56E-19 T 28-03-2018 MKLM6_RS09085 c444693bedda61177dc1a77fa37d4fb9 330 PIRSF PIRSF016766 4 329 1.9E-74 T 28-03-2018 IPR024710 Tyramine--L-glutamate ligase KEGG: 00680+6.3.4.24|MetaCyc: PWY-5254 MKLM6_RS09085 c444693bedda61177dc1a77fa37d4fb9 330 Pfam PF02655 ATP-grasp domain 127 292 9.0E-31 T 28-03-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 MKLM6_RS12655 0a26f99d6507fd2a98383a59c75d5236 267 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 262 9.3E-80 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MKLM6_RS12655 0a26f99d6507fd2a98383a59c75d5236 267 Pfam PF00290 Tryptophan synthase alpha chain 8 264 2.6E-87 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MKLM6_RS12655 0a26f99d6507fd2a98383a59c75d5236 267 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 28-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MKLM6_RS12655 0a26f99d6507fd2a98383a59c75d5236 267 SUPERFAMILY SSF51366 1 265 6.31E-91 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MKLM6_RS12655 0a26f99d6507fd2a98383a59c75d5236 267 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 264 33.941 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MKLM6_RS12655 0a26f99d6507fd2a98383a59c75d5236 267 Gene3D G3DSA:3.20.20.70 2 267 1.0E-79 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS07700 054b4ca5ddeaab9ed98e44d66c392920 126 Pfam PF01909 Nucleotidyltransferase domain 8 72 1.8E-8 T 28-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 MKLM6_RS07700 054b4ca5ddeaab9ed98e44d66c392920 126 SUPERFAMILY SSF81301 6 102 3.0E-14 T 28-03-2018 MKLM6_RS07700 054b4ca5ddeaab9ed98e44d66c392920 126 Gene3D G3DSA:3.30.460.10 4 123 1.2E-15 T 28-03-2018 MKLM6_RS17010 4c29323844578375627c18dc4583a6e9 203 Pfam PF04891 NifQ 42 200 5.0E-57 T 28-03-2018 IPR006975 NifQ GO:0009399|GO:0030151 MKLM6_RS08350 5261c2a566b92f93cc9626e5593b458b 164 Pfam PF00583 Acetyltransferase (GNAT) family 40 134 8.9E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 MKLM6_RS08350 5261c2a566b92f93cc9626e5593b458b 164 Gene3D G3DSA:3.40.630.30 88 151 5.9E-12 T 28-03-2018 MKLM6_RS08350 5261c2a566b92f93cc9626e5593b458b 164 SUPERFAMILY SSF55729 1 158 3.66E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS08350 5261c2a566b92f93cc9626e5593b458b 164 Gene3D G3DSA:3.40.630.30 1 87 5.5E-11 T 28-03-2018 MKLM6_RS01415 b1baabfda80b130b42fe8b2fde65c829 62 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 4 60 1.2E-20 T 28-03-2018 IPR012933 HicA mRNA interferase family GO:0003729 MKLM6_RS01415 b1baabfda80b130b42fe8b2fde65c829 62 SUPERFAMILY SSF54786 2 61 1.88E-16 T 28-03-2018 MKLM6_RS01415 b1baabfda80b130b42fe8b2fde65c829 62 Gene3D G3DSA:3.30.920.30 1 60 8.3E-20 T 28-03-2018 MKLM6_RS13230 8a6871ae8653d025a526d142f292a94c 294 Gene3D G3DSA:3.30.479.20 57 157 1.1E-20 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MKLM6_RS13230 8a6871ae8653d025a526d142f292a94c 294 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 293 3.4E-101 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MKLM6_RS13230 8a6871ae8653d025a526d142f292a94c 294 SUPERFAMILY SSF54713 154 293 8.9E-49 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MKLM6_RS13230 8a6871ae8653d025a526d142f292a94c 294 Gene3D G3DSA:3.30.479.20 158 291 2.4E-45 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MKLM6_RS13230 8a6871ae8653d025a526d142f292a94c 294 SUPERFAMILY SSF46934 1 55 1.47E-18 T 28-03-2018 IPR009060 UBA-like GO:0005515 MKLM6_RS13230 8a6871ae8653d025a526d142f292a94c 294 ProSitePatterns PS01126 Elongation factor Ts signature 1. 11 26 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MKLM6_RS13230 8a6871ae8653d025a526d142f292a94c 294 Gene3D G3DSA:1.10.8.10 1 55 9.0E-23 T 28-03-2018 MKLM6_RS13230 8a6871ae8653d025a526d142f292a94c 294 Hamap MF_00050 Elongation factor Ts [tsf]. 1 292 77.035 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MKLM6_RS13230 8a6871ae8653d025a526d142f292a94c 294 SUPERFAMILY SSF54713 55 146 2.94E-21 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MKLM6_RS13230 8a6871ae8653d025a526d142f292a94c 294 Pfam PF00889 Elongation factor TS 73 275 9.2E-66 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MKLM6_RS14665 eddf52e9e2ce5dc7f6b0ad66e8a7f187 607 SUPERFAMILY SSF143975 1 420 8.37E-141 T 28-03-2018 MKLM6_RS14665 eddf52e9e2ce5dc7f6b0ad66e8a7f187 607 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 154 164 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MKLM6_RS14665 eddf52e9e2ce5dc7f6b0ad66e8a7f187 607 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 507 518 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MKLM6_RS14665 eddf52e9e2ce5dc7f6b0ad66e8a7f187 607 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 2 603 2.7E-300 T 28-03-2018 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12 MKLM6_RS14665 eddf52e9e2ce5dc7f6b0ad66e8a7f187 607 Pfam PF00920 Dehydratase family 65 600 1.3E-161 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MKLM6_RS14665 eddf52e9e2ce5dc7f6b0ad66e8a7f187 607 SUPERFAMILY SSF52016 421 603 5.81E-57 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MKLM6_RS09330 7d5c303f272e70f73b72a13b32bbfe9e 308 SUPERFAMILY SSF75005 67 300 2.08E-24 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain MKLM6_RS09330 7d5c303f272e70f73b72a13b32bbfe9e 308 Gene3D G3DSA:2.115.10.20 161 305 6.8E-16 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain MKLM6_RS09330 7d5c303f272e70f73b72a13b32bbfe9e 308 Gene3D G3DSA:2.115.10.20 1 73 0.089 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain MKLM6_RS09330 7d5c303f272e70f73b72a13b32bbfe9e 308 Gene3D G3DSA:2.115.10.20 74 160 1.1E-6 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain MKLM6_RS14010 bb9fb76108954aa568b8d7e6236c6a0d 802 Pfam PF00593 TonB dependent receptor 336 800 4.9E-63 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS14010 bb9fb76108954aa568b8d7e6236c6a0d 802 Pfam PF07715 TonB-dependent Receptor Plug Domain 159 257 2.9E-13 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS14010 bb9fb76108954aa568b8d7e6236c6a0d 802 Gene3D G3DSA:2.170.130.10 119 265 1.3E-19 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS14010 bb9fb76108954aa568b8d7e6236c6a0d 802 Gene3D G3DSA:2.40.170.20 271 802 6.0E-87 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS14010 bb9fb76108954aa568b8d7e6236c6a0d 802 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 161 802 1.3E-109 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 MKLM6_RS14010 bb9fb76108954aa568b8d7e6236c6a0d 802 SMART SM00965 59 110 1.8E-7 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MKLM6_RS14010 bb9fb76108954aa568b8d7e6236c6a0d 802 SUPERFAMILY SSF56935 151 802 2.5E-130 T 28-03-2018 MKLM6_RS14490 3ded5369bd8f89e4f297ff12a68aca88 98 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 75 2.5E-13 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain MKLM6_RS14490 3ded5369bd8f89e4f297ff12a68aca88 98 SUPERFAMILY SSF54909 1 94 2.07E-25 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel MKLM6_RS14490 3ded5369bd8f89e4f297ff12a68aca88 98 Gene3D G3DSA:3.30.70.100 1 89 5.7E-23 T 28-03-2018 MKLM6_RS20805 fd21869d57bce5eaa346389b7d54abb8 361 SMART SM00448 6 129 5.6E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS20805 fd21869d57bce5eaa346389b7d54abb8 361 Pfam PF00072 Response regulator receiver domain 8 110 9.9E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS20805 fd21869d57bce5eaa346389b7d54abb8 361 Pfam PF01339 CheB methylesterase 178 356 3.2E-59 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MKLM6_RS20805 fd21869d57bce5eaa346389b7d54abb8 361 SUPERFAMILY SSF52738 174 359 1.96E-68 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MKLM6_RS20805 fd21869d57bce5eaa346389b7d54abb8 361 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 6 361 38.936 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MKLM6_RS20805 fd21869d57bce5eaa346389b7d54abb8 361 Gene3D G3DSA:3.40.50.2300 5 154 4.1E-28 T 28-03-2018 MKLM6_RS20805 fd21869d57bce5eaa346389b7d54abb8 361 PIRSF PIRSF000876 3 361 1.7E-128 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MKLM6_RS20805 fd21869d57bce5eaa346389b7d54abb8 361 SUPERFAMILY SSF52172 4 110 2.13E-27 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS20805 fd21869d57bce5eaa346389b7d54abb8 361 Gene3D G3DSA:3.40.50.180 166 361 1.9E-73 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MKLM6_RS22135 fbf0e89bd726611a6bc32105f1696559 260 Pfam PF03466 LysR substrate binding domain 62 257 2.4E-35 T 28-03-2018 IPR005119 LysR, substrate-binding MKLM6_RS22135 fbf0e89bd726611a6bc32105f1696559 260 Gene3D G3DSA:3.40.190.10 58 145 1.1E-17 T 28-03-2018 MKLM6_RS22135 fbf0e89bd726611a6bc32105f1696559 260 Gene3D G3DSA:3.40.190.10 146 230 1.9E-15 T 28-03-2018 MKLM6_RS22135 fbf0e89bd726611a6bc32105f1696559 260 SUPERFAMILY SSF53850 62 257 1.4E-31 T 28-03-2018 MKLM6_RS06440 0b6a4a057c9dd2a60f14f0a983bcaf64 182 SUPERFAMILY SSF54211 4 175 5.16E-52 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS06440 0b6a4a057c9dd2a60f14f0a983bcaf64 182 TIGRFAM TIGR03126 one_C_fae: formaldehyde-activating enzyme 8 171 2.0E-35 T 28-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 MKLM6_RS06440 0b6a4a057c9dd2a60f14f0a983bcaf64 182 Pfam PF08714 Formaldehyde-activating enzyme (Fae) 9 173 5.6E-59 T 28-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 MKLM6_RS06440 0b6a4a057c9dd2a60f14f0a983bcaf64 182 Gene3D G3DSA:3.30.230.60 7 174 1.1E-56 T 28-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 MKLM6_RS17105 c8a9a085b70d86e88ba1ae0ee9814715 605 Gene3D G3DSA:1.20.5.50 403 461 0.0013 T 28-03-2018 MKLM6_RS00080 a9c594c65c4f761d39e05db4e7e6e12c 151 SUPERFAMILY SSF109604 62 111 2.73E-7 T 28-03-2018 MKLM6_RS00080 a9c594c65c4f761d39e05db4e7e6e12c 151 SUPERFAMILY SSF53098 21 70 4.55E-7 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS00080 a9c594c65c4f761d39e05db4e7e6e12c 151 Gene3D G3DSA:3.30.420.10 5 125 9.2E-8 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS00080 a9c594c65c4f761d39e05db4e7e6e12c 151 Pfam PF13328 HD domain 58 127 3.6E-8 T 28-03-2018 IPR003607 HD/PDEase domain MKLM6_RS00415 7fea5ff2054f9b18cde434a72c4435f1 313 Pfam PF01738 Dienelactone hydrolase family 81 267 2.6E-8 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 MKLM6_RS00415 7fea5ff2054f9b18cde434a72c4435f1 313 SUPERFAMILY SSF53474 65 283 1.39E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS00415 7fea5ff2054f9b18cde434a72c4435f1 313 Gene3D G3DSA:3.40.50.1820 55 283 1.0E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS04025 92df7a0527bc4d54e9a39182c0db418b 611 Pfam PF00092 von Willebrand factor type A domain 32 205 1.0E-13 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS04025 92df7a0527bc4d54e9a39182c0db418b 611 SMART SM00327 30 208 1.2E-9 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS04025 92df7a0527bc4d54e9a39182c0db418b 611 SUPERFAMILY SSF53300 29 214 5.4E-21 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS04025 92df7a0527bc4d54e9a39182c0db418b 611 Gene3D G3DSA:3.40.50.410 21 220 1.2E-22 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS06100 03e27d6a2bd6353f48d4dd84d5a7b7d7 566 Pfam PF00069 Protein kinase domain 154 382 1.6E-37 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MKLM6_RS06100 03e27d6a2bd6353f48d4dd84d5a7b7d7 566 Gene3D G3DSA:3.30.200.20 142 225 1.7E-15 T 28-03-2018 MKLM6_RS06100 03e27d6a2bd6353f48d4dd84d5a7b7d7 566 Gene3D G3DSA:1.10.510.10 226 559 1.1E-43 T 28-03-2018 MKLM6_RS06100 03e27d6a2bd6353f48d4dd84d5a7b7d7 566 SUPERFAMILY SSF56112 144 414 1.48E-55 T 28-03-2018 IPR011009 Protein kinase-like domain MKLM6_RS06100 03e27d6a2bd6353f48d4dd84d5a7b7d7 566 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 279 291 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MKLM6_RS06100 03e27d6a2bd6353f48d4dd84d5a7b7d7 566 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 158 187 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 MKLM6_RS11440 f8ee6256a403f02307087d5970b1b5bb 732 SUPERFAMILY SSF55073 317 475 4.24E-48 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS11440 f8ee6256a403f02307087d5970b1b5bb 732 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 308 474 2.9E-52 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS11440 f8ee6256a403f02307087d5970b1b5bb 732 Gene3D G3DSA:3.20.20.450 477 731 3.0E-71 T 28-03-2018 IPR001633 EAL domain MKLM6_RS11440 f8ee6256a403f02307087d5970b1b5bb 732 Pfam PF00563 EAL domain 492 725 1.5E-60 T 28-03-2018 IPR001633 EAL domain MKLM6_RS11440 f8ee6256a403f02307087d5970b1b5bb 732 Gene3D G3DSA:3.30.70.270 305 476 3.1E-57 T 28-03-2018 MKLM6_RS11440 f8ee6256a403f02307087d5970b1b5bb 732 SUPERFAMILY SSF141868 492 728 1.44E-67 T 28-03-2018 IPR001633 EAL domain MKLM6_RS11440 f8ee6256a403f02307087d5970b1b5bb 732 SMART SM00267 301 474 2.8E-63 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS11440 f8ee6256a403f02307087d5970b1b5bb 732 SMART SM00052 486 732 1.6E-58 T 28-03-2018 IPR001633 EAL domain MKLM6_RS11440 f8ee6256a403f02307087d5970b1b5bb 732 Pfam PF00990 Diguanylate cyclase, GGDEF domain 313 469 6.0E-48 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS04530 bad4fc743571d7dacce862f81d0ce6ca 452 ProSitePatterns PS00543 HlyD family secretion proteins signature. 416 438 - T 28-03-2018 IPR006144 Secretion protein HlyD, conserved site GO:0008565|GO:0009306|GO:0016020 MKLM6_RS04530 bad4fc743571d7dacce862f81d0ce6ca 452 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 38 452 1.9E-124 T 28-03-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 MKLM6_RS04530 bad4fc743571d7dacce862f81d0ce6ca 452 Gene3D G3DSA:2.40.50.100 66 338 1.2E-16 T 28-03-2018 MKLM6_RS04530 bad4fc743571d7dacce862f81d0ce6ca 452 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 416 431 7.0E-40 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MKLM6_RS04530 bad4fc743571d7dacce862f81d0ce6ca 452 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 45 68 7.0E-40 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MKLM6_RS04530 bad4fc743571d7dacce862f81d0ce6ca 452 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 431 451 7.0E-40 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MKLM6_RS04530 bad4fc743571d7dacce862f81d0ce6ca 452 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 371 394 7.0E-40 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MKLM6_RS04530 bad4fc743571d7dacce862f81d0ce6ca 452 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 347 371 7.0E-40 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MKLM6_RS04530 bad4fc743571d7dacce862f81d0ce6ca 452 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 314 335 7.0E-40 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MKLM6_RS04530 bad4fc743571d7dacce862f81d0ce6ca 452 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 87 107 7.0E-40 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MKLM6_RS04530 bad4fc743571d7dacce862f81d0ce6ca 452 Pfam PF13437 HlyD family secretion protein 302 406 3.0E-16 T 28-03-2018 MKLM6_RS04530 bad4fc743571d7dacce862f81d0ce6ca 452 Pfam PF13533 Biotin-lipoyl like 82 113 1.9E-6 T 28-03-2018 MKLM6_RS19960 3d5dbc6a68809d37f57f56b377048a33 208 SUPERFAMILY SSF53850 1 202 1.19E-65 T 28-03-2018 MKLM6_RS19960 3d5dbc6a68809d37f57f56b377048a33 208 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 182 5.4E-56 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MKLM6_RS19960 3d5dbc6a68809d37f57f56b377048a33 208 Gene3D G3DSA:3.40.190.10 1 111 9.4E-37 T 28-03-2018 MKLM6_RS19960 3d5dbc6a68809d37f57f56b377048a33 208 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 1 206 54.344 T 28-03-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 MKLM6_RS19960 3d5dbc6a68809d37f57f56b377048a33 208 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 141 162 - T 28-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 MKLM6_RS19960 3d5dbc6a68809d37f57f56b377048a33 208 Pfam PF01634 ATP phosphoribosyltransferase 51 201 6.2E-49 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MKLM6_RS19960 3d5dbc6a68809d37f57f56b377048a33 208 Gene3D G3DSA:3.40.190.10 112 173 1.8E-25 T 28-03-2018 MKLM6_RS19260 a53809aab85a2a41f5ebd32eff899b8d 211 Pfam PF01914 MarC family integral membrane protein 3 205 1.8E-57 T 28-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 MKLM6_RS19260 a53809aab85a2a41f5ebd32eff899b8d 211 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 5 201 3.7E-58 T 28-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 MKLM6_RS08515 55ac67a428e0af5adfa378c13c26f1ba 568 SUPERFAMILY SSF52540 352 542 3.92E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS08515 55ac67a428e0af5adfa378c13c26f1ba 568 Gene3D G3DSA:3.40.50.300 361 503 2.0E-19 T 28-03-2018 MKLM6_RS08515 55ac67a428e0af5adfa378c13c26f1ba 568 Gene3D G3DSA:1.10.8.60 504 557 3.1E-5 T 28-03-2018 MKLM6_RS08515 55ac67a428e0af5adfa378c13c26f1ba 568 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 368 481 6.9E-15 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MKLM6_RS09775 75f5022a92baf0c7d6052fc9c1717d13 95 SUPERFAMILY SSF47598 8 85 2.67E-18 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 MKLM6_RS09775 75f5022a92baf0c7d6052fc9c1717d13 95 Gene3D G3DSA:1.20.5.780 8 86 3.0E-23 T 28-03-2018 MKLM6_RS09775 75f5022a92baf0c7d6052fc9c1717d13 95 Pfam PF08681 Protein of unknown function (DUF1778) 11 86 6.4E-22 T 28-03-2018 IPR014795 Vibrio phage ICP1, Orf50 MKLM6_RS15730 539938166ec21646927cf57ffe21b014 387 Gene3D G3DSA:3.40.50.2000 5 193 9.4E-17 T 28-03-2018 MKLM6_RS15730 539938166ec21646927cf57ffe21b014 387 Pfam PF13439 Glycosyltransferase Family 4 20 183 3.1E-17 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MKLM6_RS15730 539938166ec21646927cf57ffe21b014 387 Pfam PF13692 Glycosyl transferases group 1 208 344 1.1E-25 T 28-03-2018 MKLM6_RS15730 539938166ec21646927cf57ffe21b014 387 Gene3D G3DSA:3.40.50.2000 194 365 9.0E-41 T 28-03-2018 MKLM6_RS15730 539938166ec21646927cf57ffe21b014 387 SUPERFAMILY SSF53756 11 378 6.28E-70 T 28-03-2018 MKLM6_RS15575 f978d84d9e5905d14f552469dff6e5db 227 SUPERFAMILY SSF56281 21 217 6.59E-12 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS15575 f978d84d9e5905d14f552469dff6e5db 227 Pfam PF14234 Domain of unknown function (DUF4336) 8 149 1.5E-18 T 28-03-2018 IPR025638 Protein of unknown function DUF4336 MKLM6_RS15575 f978d84d9e5905d14f552469dff6e5db 227 Gene3D G3DSA:3.60.15.10 18 227 1.5E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS16390 58f1d75e1c7f9dd52cda26d9b0bcd202 180 Pfam PF01327 Polypeptide deformylase 5 160 3.9E-47 T 28-03-2018 IPR023635 Peptide deformylase MKLM6_RS16390 58f1d75e1c7f9dd52cda26d9b0bcd202 180 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 9 162 1.1E-36 T 28-03-2018 IPR023635 Peptide deformylase MKLM6_RS16390 58f1d75e1c7f9dd52cda26d9b0bcd202 180 PRINTS PR01576 Peptide deformylase signature 35 64 3.0E-29 T 28-03-2018 IPR023635 Peptide deformylase MKLM6_RS16390 58f1d75e1c7f9dd52cda26d9b0bcd202 180 PRINTS PR01576 Peptide deformylase signature 111 129 3.0E-29 T 28-03-2018 IPR023635 Peptide deformylase MKLM6_RS16390 58f1d75e1c7f9dd52cda26d9b0bcd202 180 PRINTS PR01576 Peptide deformylase signature 130 159 3.0E-29 T 28-03-2018 IPR023635 Peptide deformylase MKLM6_RS16390 58f1d75e1c7f9dd52cda26d9b0bcd202 180 PRINTS PR01576 Peptide deformylase signature 99 110 3.0E-29 T 28-03-2018 IPR023635 Peptide deformylase MKLM6_RS16390 58f1d75e1c7f9dd52cda26d9b0bcd202 180 PIRSF PIRSF004749 1 179 4.4E-50 T 28-03-2018 IPR023635 Peptide deformylase MKLM6_RS16390 58f1d75e1c7f9dd52cda26d9b0bcd202 180 Hamap MF_00163 Peptide deformylase [def]. 3 172 25.453 T 28-03-2018 IPR023635 Peptide deformylase MKLM6_RS16390 58f1d75e1c7f9dd52cda26d9b0bcd202 180 SUPERFAMILY SSF56420 5 171 6.8E-51 T 28-03-2018 IPR023635 Peptide deformylase MKLM6_RS16390 58f1d75e1c7f9dd52cda26d9b0bcd202 180 Gene3D G3DSA:3.90.45.10 1 179 1.4E-51 T 28-03-2018 IPR023635 Peptide deformylase MKLM6_RS17610 7197c258387bb4bcdd81c3db260ab426 180 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 1 176 18.331 T 28-03-2018 IPR006008 Intracellular septation protein A GO:0016021 MKLM6_RS17610 7197c258387bb4bcdd81c3db260ab426 180 TIGRFAM TIGR00997 ispZ: intracellular septation protein A 1 175 2.4E-56 T 28-03-2018 IPR006008 Intracellular septation protein A GO:0016021 MKLM6_RS17610 7197c258387bb4bcdd81c3db260ab426 180 Pfam PF04279 Intracellular septation protein A 1 174 6.5E-67 T 28-03-2018 IPR006008 Intracellular septation protein A GO:0016021 MKLM6_RS06405 12c75ab6dd2250b8fdffc708ba451951 77 Pfam PF02609 Exonuclease VII small subunit 10 61 8.4E-22 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MKLM6_RS06405 12c75ab6dd2250b8fdffc708ba451951 77 SUPERFAMILY SSF116842 3 72 6.54E-23 T 28-03-2018 MKLM6_RS06405 12c75ab6dd2250b8fdffc708ba451951 77 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 5 50 1.0E-10 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MKLM6_RS06405 12c75ab6dd2250b8fdffc708ba451951 77 Gene3D G3DSA:1.10.287.1040 7 74 6.9E-26 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MKLM6_RS06405 12c75ab6dd2250b8fdffc708ba451951 77 PIRSF PIRSF006488 1 77 5.7E-24 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MKLM6_RS06405 12c75ab6dd2250b8fdffc708ba451951 77 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 9 69 16.286 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MKLM6_RS06405 12c75ab6dd2250b8fdffc708ba451951 77 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 10 64 5.6E-24 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MKLM6_RS19035 a1df1c0667375a8dc855c6f03da69de8 1135 Gene3D G3DSA:3.40.50.300 693 847 2.9E-10 T 28-03-2018 MKLM6_RS19035 a1df1c0667375a8dc855c6f03da69de8 1135 Pfam PF00271 Helicase conserved C-terminal domain 717 818 3.2E-5 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS19035 a1df1c0667375a8dc855c6f03da69de8 1135 Gene3D G3DSA:3.40.50.300 381 627 4.3E-23 T 28-03-2018 MKLM6_RS19035 a1df1c0667375a8dc855c6f03da69de8 1135 SMART SM00487 422 647 3.8E-11 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MKLM6_RS19035 a1df1c0667375a8dc855c6f03da69de8 1135 Pfam PF04851 Type III restriction enzyme, res subunit 424 612 1.1E-32 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MKLM6_RS19035 a1df1c0667375a8dc855c6f03da69de8 1135 SUPERFAMILY SSF52540 681 825 3.39E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS19035 a1df1c0667375a8dc855c6f03da69de8 1135 SUPERFAMILY SSF52540 444 614 3.39E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS19035 a1df1c0667375a8dc855c6f03da69de8 1135 Pfam PF13643 Domain of unknown function (DUF4145) 22 112 2.1E-8 T 28-03-2018 IPR025285 Domain of unknown function DUF4145 MKLM6_RS19035 a1df1c0667375a8dc855c6f03da69de8 1135 Pfam PF08463 EcoEI R protein C-terminal 973 1134 3.7E-29 T 28-03-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 MKLM6_RS19035 a1df1c0667375a8dc855c6f03da69de8 1135 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 250 364 3.8E-8 T 28-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 MKLM6_RS00385 3c103385dd454f91723a720856475e20 676 Pfam PF00672 HAMP domain 345 390 3.5E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS00385 3c103385dd454f91723a720856475e20 676 SUPERFAMILY SSF58104 365 674 1.15E-79 T 28-03-2018 MKLM6_RS00385 3c103385dd454f91723a720856475e20 676 SMART SM00304 345 397 1.9E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS00385 3c103385dd454f91723a720856475e20 676 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 457 640 3.0E-44 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS00385 3c103385dd454f91723a720856475e20 676 Gene3D G3DSA:1.10.287.950 438 676 1.2E-56 T 28-03-2018 MKLM6_RS00385 3c103385dd454f91723a720856475e20 676 SMART SM00283 412 673 2.9E-89 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS16655 a2151f124321de4546cb45457f8da369 378 SMART SM00283 38 268 3.2E-17 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS16655 a2151f124321de4546cb45457f8da369 378 Pfam PF13682 Chemoreceptor zinc-binding domain 262 328 5.1E-12 T 28-03-2018 IPR025991 Chemoreceptor zinc-binding domain MKLM6_RS16655 a2151f124321de4546cb45457f8da369 378 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 122 237 5.6E-32 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS16655 a2151f124321de4546cb45457f8da369 378 SUPERFAMILY SSF58104 24 246 1.57E-43 T 28-03-2018 MKLM6_RS16655 a2151f124321de4546cb45457f8da369 378 Gene3D G3DSA:1.20.5.340 7 81 8.6E-4 T 28-03-2018 MKLM6_RS16655 a2151f124321de4546cb45457f8da369 378 Gene3D G3DSA:1.10.287.950 82 377 6.6E-38 T 28-03-2018 MKLM6_RS19390 7d5b71372962a39540042a8dce2b3b16 346 Pfam PF13528 Glycosyl transferase family 1 1 124 2.4E-13 T 28-03-2018 MKLM6_RS19390 7d5b71372962a39540042a8dce2b3b16 346 Pfam PF13528 Glycosyl transferase family 1 163 300 5.6E-20 T 28-03-2018 MKLM6_RS19390 7d5b71372962a39540042a8dce2b3b16 346 SUPERFAMILY SSF53756 10 287 2.51E-6 T 28-03-2018 MKLM6_RS19390 7d5b71372962a39540042a8dce2b3b16 346 Gene3D G3DSA:3.40.50.2000 3 302 2.4E-9 T 28-03-2018 MKLM6_RS19390 7d5b71372962a39540042a8dce2b3b16 346 TIGRFAM TIGR00661 MJ1255: conserved hypothetical protein 2 309 7.2E-66 T 28-03-2018 IPR005262 Conserved hypothetical protein CHP00661 MKLM6_RS06365 0a55a1a4de311253bed9d7f52c1bb3d9 652 Gene3D G3DSA:1.50.10.20 10 61 0.28 T 28-03-2018 MKLM6_RS06365 0a55a1a4de311253bed9d7f52c1bb3d9 652 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 31 647 2.1E-202 T 28-03-2018 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 MKLM6_RS06365 0a55a1a4de311253bed9d7f52c1bb3d9 652 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 27 649 7.2E-269 T 28-03-2018 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00030+4.2.1.12|KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072 MKLM6_RS06365 0a55a1a4de311253bed9d7f52c1bb3d9 652 Gene3D G3DSA:1.50.10.20 62 314 2.9E-65 T 28-03-2018 MKLM6_RS06365 0a55a1a4de311253bed9d7f52c1bb3d9 652 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 327 647 3.1E-135 T 28-03-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 MKLM6_RS06365 0a55a1a4de311253bed9d7f52c1bb3d9 652 SUPERFAMILY SSF48239 323 647 6.2E-98 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid MKLM6_RS06365 0a55a1a4de311253bed9d7f52c1bb3d9 652 SUPERFAMILY SSF48239 254 278 6.2E-98 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid MKLM6_RS06365 0a55a1a4de311253bed9d7f52c1bb3d9 652 SUPERFAMILY SSF48239 57 323 1.18E-71 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid MKLM6_RS06365 0a55a1a4de311253bed9d7f52c1bb3d9 652 Gene3D G3DSA:1.50.10.20 315 652 3.8E-99 T 28-03-2018 MKLM6_RS06365 0a55a1a4de311253bed9d7f52c1bb3d9 652 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 32 319 1.4E-113 T 28-03-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 MKLM6_RS04175 a67bdd32ca19b009c6b09d9023b55e3a 78 SUPERFAMILY SSF47598 3 58 4.56E-14 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 MKLM6_RS04175 a67bdd32ca19b009c6b09d9023b55e3a 78 Gene3D G3DSA:1.10.1220.10 1 74 3.8E-8 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 MKLM6_RS15055 70eeed7fcfd0c43e283fefe70860d275 292 SUPERFAMILY SSF51735 6 167 2.27E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS15055 70eeed7fcfd0c43e283fefe70860d275 292 Gene3D G3DSA:3.40.50.720 1 175 9.0E-35 T 28-03-2018 MKLM6_RS15055 70eeed7fcfd0c43e283fefe70860d275 292 Gene3D G3DSA:1.10.1040.10 176 292 5.8E-26 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MKLM6_RS15055 70eeed7fcfd0c43e283fefe70860d275 292 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 168 287 4.1E-24 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MKLM6_RS15055 70eeed7fcfd0c43e283fefe70860d275 292 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 165 5.7E-44 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 MKLM6_RS15055 70eeed7fcfd0c43e283fefe70860d275 292 SUPERFAMILY SSF48179 166 289 2.04E-28 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MKLM6_RS15055 70eeed7fcfd0c43e283fefe70860d275 292 PIRSF PIRSF000103 1 292 3.0E-62 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 MKLM6_RS07515 b15238895ceb04580395615c1441f1a5 90 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 25 89 5.5E-8 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MKLM6_RS07515 b15238895ceb04580395615c1441f1a5 90 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 24 84 9.1E-7 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MKLM6_RS07515 b15238895ceb04580395615c1441f1a5 90 SUPERFAMILY SSF143011 4 88 1.15E-20 T 28-03-2018 IPR035095 Toxin RelE-like domain MKLM6_RS07515 b15238895ceb04580395615c1441f1a5 90 Gene3D G3DSA:3.30.2310.20 1 90 5.0E-21 T 28-03-2018 MKLM6_RS02095 589ba1e4f41416be798a65077d7cc3bb 188 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 5 188 37.163 T 28-03-2018 IPR003774 Protein of unknown function UPF0301 MKLM6_RS02095 589ba1e4f41416be798a65077d7cc3bb 188 Pfam PF02622 Uncharacterized ACR, COG1678 16 175 6.9E-49 T 28-03-2018 IPR003774 Protein of unknown function UPF0301 MKLM6_RS02095 589ba1e4f41416be798a65077d7cc3bb 188 Gene3D G3DSA:3.30.70.1300 46 120 6.2E-28 T 28-03-2018 MKLM6_RS02095 589ba1e4f41416be798a65077d7cc3bb 188 Gene3D G3DSA:3.40.1740.10 121 180 4.1E-10 T 28-03-2018 MKLM6_RS02095 589ba1e4f41416be798a65077d7cc3bb 188 SUPERFAMILY SSF143456 5 184 7.72E-62 T 28-03-2018 MKLM6_RS08535 5fed2b5791b890cdf5d1f7dd78be948f 365 Pfam PF01609 Transposase DDE domain 199 346 8.1E-14 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS08535 5fed2b5791b890cdf5d1f7dd78be948f 365 Pfam PF05598 Transposase domain (DUF772) 53 128 2.5E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS12575 f5bc36a3df47edb5802e2db6746e9d23 162 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 17 153 2.1E-56 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MKLM6_RS12575 f5bc36a3df47edb5802e2db6746e9d23 162 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 11 156 30.853 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MKLM6_RS12575 f5bc36a3df47edb5802e2db6746e9d23 162 SUPERFAMILY SSF52121 7 159 3.27E-60 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MKLM6_RS12575 f5bc36a3df47edb5802e2db6746e9d23 162 Gene3D G3DSA:3.40.50.960 4 157 4.5E-61 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MKLM6_RS12575 f5bc36a3df47edb5802e2db6746e9d23 162 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 17 152 5.7E-55 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MKLM6_RS02280 56d00e52e4736d914a616a580cc43d31 110 PIRSF PIRSF028744 1 105 6.6E-34 T 28-03-2018 IPR014056 Addiction module killer protein, predicted MKLM6_RS02280 56d00e52e4736d914a616a580cc43d31 110 TIGRFAM TIGR02683 upstrm_HI1419: putative addiction module killer protein 10 99 1.1E-29 T 28-03-2018 IPR014056 Addiction module killer protein, predicted MKLM6_RS02280 56d00e52e4736d914a616a580cc43d31 110 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 17 97 2.2E-10 T 28-03-2018 IPR009241 Toxin HigB-like MKLM6_RS17030 b5f0cd60dcb7c9464e0f1ae707bd47e6 141 SUPERFAMILY SSF52833 3 120 2.03E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS17030 b5f0cd60dcb7c9464e0f1ae707bd47e6 141 Gene3D G3DSA:3.40.30.10 1 129 2.9E-20 T 28-03-2018 MKLM6_RS17030 b5f0cd60dcb7c9464e0f1ae707bd47e6 141 TIGRFAM TIGR01616 nitro_assoc: nitrogenase-associated protein 2 130 3.1E-52 T 28-03-2018 IPR006503 Nitrogenase-associated protein MKLM6_RS17030 b5f0cd60dcb7c9464e0f1ae707bd47e6 141 Pfam PF03960 ArsC family 64 114 3.2E-10 T 28-03-2018 IPR006660 Arsenate reductase-like MKLM6_RS18460 b8ffe7ba84fb53af25ffdb577476148f 156 PIRSF PIRSF002122 3 156 2.0E-59 T 28-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 MKLM6_RS18460 b8ffe7ba84fb53af25ffdb577476148f 156 Gene3D G3DSA:1.10.455.10 6 156 2.3E-60 T 28-03-2018 IPR023798 Ribosomal protein S7 domain MKLM6_RS18460 b8ffe7ba84fb53af25ffdb577476148f 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 3.9E-65 T 28-03-2018 IPR023798 Ribosomal protein S7 domain MKLM6_RS18460 b8ffe7ba84fb53af25ffdb577476148f 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 28-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18460 b8ffe7ba84fb53af25ffdb577476148f 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 4.7E-67 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 MKLM6_RS18460 b8ffe7ba84fb53af25ffdb577476148f 156 SUPERFAMILY SSF47973 6 149 8.24E-58 T 28-03-2018 IPR023798 Ribosomal protein S7 domain MKLM6_RS18460 b8ffe7ba84fb53af25ffdb577476148f 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.967 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 MKLM6_RS04705 edc4a12134ab137669adf597aa247377 124 SUPERFAMILY SSF54593 8 123 2.6E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MKLM6_RS04705 edc4a12134ab137669adf597aa247377 124 Gene3D G3DSA:3.10.180.10 6 123 7.7E-12 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MKLM6_RS04450 f499e69241e485c901e716c736adc3ab 98 SUPERFAMILY SSF102829 8 95 1.06E-18 T 28-03-2018 IPR007838 Cell division protein ZapA-like MKLM6_RS04450 f499e69241e485c901e716c736adc3ab 98 Pfam PF05164 Cell division protein ZapA 8 88 4.6E-19 T 28-03-2018 IPR007838 Cell division protein ZapA-like MKLM6_RS10910 86ffb4dd557d09f910b57d94b27f27b9 460 SMART SM00729 54 277 5.4E-47 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MKLM6_RS10910 86ffb4dd557d09f910b57d94b27f27b9 460 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 7 460 7.1E-194 T 28-03-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 MKLM6_RS10910 86ffb4dd557d09f910b57d94b27f27b9 460 PIRSF PIRSF000167 4 460 9.7E-169 T 28-03-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 MKLM6_RS10910 86ffb4dd557d09f910b57d94b27f27b9 460 Gene3D G3DSA:3.20.20.70 30 358 4.1E-45 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS10910 86ffb4dd557d09f910b57d94b27f27b9 460 Pfam PF06969 HemN C-terminal domain 368 436 3.2E-9 T 28-03-2018 IPR010723 HemN, C-terminal MKLM6_RS10910 86ffb4dd557d09f910b57d94b27f27b9 460 SUPERFAMILY SSF102114 6 449 4.97E-135 T 28-03-2018 MKLM6_RS10910 86ffb4dd557d09f910b57d94b27f27b9 460 Pfam PF04055 Radical SAM superfamily 60 233 2.1E-17 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS07090 543bc778f194a47ae3249068461bc3d7 165 Hamap MF_00269 Probable thiol peroxidase [tpx]. 3 165 36.0 T 28-03-2018 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 MKLM6_RS07090 543bc778f194a47ae3249068461bc3d7 165 SUPERFAMILY SSF52833 1 162 1.41E-41 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS07090 543bc778f194a47ae3249068461bc3d7 165 ProSitePatterns PS01265 Tpx family signature. 83 94 - T 28-03-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 MKLM6_RS07090 543bc778f194a47ae3249068461bc3d7 165 Pfam PF08534 Redoxin 20 161 7.8E-25 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 MKLM6_RS07090 543bc778f194a47ae3249068461bc3d7 165 Gene3D G3DSA:3.40.30.10 2 165 4.6E-22 T 28-03-2018 MKLM6_RS07395 b1cfa24148da5395290759c0591102d1 61 Gene3D G3DSA:3.30.50.10 2 61 1.4E-4 T 28-03-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 MKLM6_RS07395 b1cfa24148da5395290759c0591102d1 61 Pfam PF12156 Putative metal-binding domain of cation transport ATPase 9 48 2.5E-7 T 28-03-2018 IPR021993 Putative metal-binding domain of cation transport ATPase MKLM6_RS10275 fadd5fa71e5110641599e29384fa209a 187 Gene3D G3DSA:2.30.110.10 1 117 9.7E-16 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MKLM6_RS10275 fadd5fa71e5110641599e29384fa209a 187 SUPERFAMILY SSF50475 1 179 4.12E-51 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MKLM6_RS10275 fadd5fa71e5110641599e29384fa209a 187 Pfam PF04289 Protein of unknown function (DUF447) 4 175 4.2E-44 T 28-03-2018 IPR007386 Protein of unknown function DUF447 MKLM6_RS10275 fadd5fa71e5110641599e29384fa209a 187 Gene3D G3DSA:1.20.58.290 118 180 1.4E-27 T 28-03-2018 MKLM6_RS01325 b9b07bf9d74590b7cf3e5dd2af8594f1 294 SUPERFAMILY SSF46785 1 86 4.12E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS01325 b9b07bf9d74590b7cf3e5dd2af8594f1 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.2E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS01325 b9b07bf9d74590b7cf3e5dd2af8594f1 294 Gene3D G3DSA:3.40.190.10 92 176 2.1E-18 T 28-03-2018 MKLM6_RS01325 b9b07bf9d74590b7cf3e5dd2af8594f1 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.0E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS01325 b9b07bf9d74590b7cf3e5dd2af8594f1 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.0E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS01325 b9b07bf9d74590b7cf3e5dd2af8594f1 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.0E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS01325 b9b07bf9d74590b7cf3e5dd2af8594f1 294 Gene3D G3DSA:3.40.190.10 177 267 1.3E-20 T 28-03-2018 MKLM6_RS01325 b9b07bf9d74590b7cf3e5dd2af8594f1 294 Pfam PF03466 LysR substrate binding domain 88 291 2.1E-41 T 28-03-2018 IPR005119 LysR, substrate-binding MKLM6_RS01325 b9b07bf9d74590b7cf3e5dd2af8594f1 294 Gene3D G3DSA:1.10.10.10 1 91 1.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS01325 b9b07bf9d74590b7cf3e5dd2af8594f1 294 SUPERFAMILY SSF53850 88 290 1.38E-39 T 28-03-2018 MKLM6_RS11550 ec8966725d086f3247ac684726ae2c16 256 SUPERFAMILY SSF55486 40 248 7.18E-40 T 28-03-2018 MKLM6_RS11550 ec8966725d086f3247ac684726ae2c16 256 Gene3D G3DSA:3.40.390.10 121 250 7.0E-24 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 MKLM6_RS11550 ec8966725d086f3247ac684726ae2c16 256 Pfam PF06167 Glucose-regulated metallo-peptidase M90 6 247 2.2E-87 T 28-03-2018 IPR010384 MtfA family MKLM6_RS17005 9ba6f9f0e5b07ec4abb6c19cbc1bdcce 778 Gene3D G3DSA:2.170.130.10 24 170 1.3E-20 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS17005 9ba6f9f0e5b07ec4abb6c19cbc1bdcce 778 Pfam PF00593 TonB dependent receptor 322 777 4.2E-38 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS17005 9ba6f9f0e5b07ec4abb6c19cbc1bdcce 778 Gene3D G3DSA:2.40.170.20 179 778 2.7E-51 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS17005 9ba6f9f0e5b07ec4abb6c19cbc1bdcce 778 Pfam PF07715 TonB-dependent Receptor Plug Domain 53 165 2.0E-15 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS17005 9ba6f9f0e5b07ec4abb6c19cbc1bdcce 778 SUPERFAMILY SSF56935 26 232 3.36E-79 T 28-03-2018 MKLM6_RS17005 9ba6f9f0e5b07ec4abb6c19cbc1bdcce 778 SUPERFAMILY SSF56935 275 778 3.36E-79 T 28-03-2018 MKLM6_RS02655 3655182bc0e5166111668c19f0a92cd2 322 Pfam PF08003 Protein of unknown function (DUF1698) 8 320 1.9E-132 T 28-03-2018 IPR027555 tRNA (mo5U34)-methyltransferase-like MKLM6_RS02655 3655182bc0e5166111668c19f0a92cd2 322 TIGRFAM TIGR00452 TIGR00452: tRNA (mo5U34)-methyltransferase 8 320 3.1E-142 T 28-03-2018 IPR010017 tRNA U34 carboxymethyltransferase GO:0002098|GO:0016765 MKLM6_RS02655 3655182bc0e5166111668c19f0a92cd2 322 Hamap MF_01590 tRNA U34 carboxymethyltransferase [cmoB]. 14 322 51.464 T 28-03-2018 IPR010017 tRNA U34 carboxymethyltransferase GO:0002098|GO:0016765 MKLM6_RS02655 3655182bc0e5166111668c19f0a92cd2 322 Gene3D G3DSA:3.40.50.150 32 299 9.4E-21 T 28-03-2018 MKLM6_RS02655 3655182bc0e5166111668c19f0a92cd2 322 SUPERFAMILY SSF53335 91 320 8.21E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS04730 0b825fafa7d46f2b19c5a2e38cba8331 148 Gene3D G3DSA:1.20.5.1230 16 145 9.3E-4 T 28-03-2018 MKLM6_RS01460 b07b3eae4eb57739803ed8e1c177592f 81 Pfam PF00037 4Fe-4S binding domain 4 25 2.5E-6 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MKLM6_RS01460 b07b3eae4eb57739803ed8e1c177592f 81 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MKLM6_RS01460 b07b3eae4eb57739803ed8e1c177592f 81 SUPERFAMILY SSF54862 4 71 7.54E-20 T 28-03-2018 MKLM6_RS01460 b07b3eae4eb57739803ed8e1c177592f 81 Gene3D G3DSA:3.30.70.20 2 50 2.9E-14 T 28-03-2018 MKLM6_RS01460 b07b3eae4eb57739803ed8e1c177592f 81 Gene3D G3DSA:3.30.70.20 51 76 0.0089 T 28-03-2018 MKLM6_RS17395 5e113bba635f34447ca2e5b774c51970 230 SUPERFAMILY SSF53146 96 214 1.09E-30 T 28-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis MKLM6_RS17395 5e113bba635f34447ca2e5b774c51970 230 Pfam PF16844 Dinitrogenase iron-molybdenum cofactor, N-terminal 6 78 4.6E-12 T 28-03-2018 IPR031763 Dinitrogenase iron-molybdenum cofactor, N-terminal MKLM6_RS17395 5e113bba635f34447ca2e5b774c51970 230 Gene3D G3DSA:3.30.420.130 94 216 6.1E-31 T 28-03-2018 MKLM6_RS17395 5e113bba635f34447ca2e5b774c51970 230 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 108 201 7.7E-19 T 28-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis MKLM6_RS01810 5dca0f6bd53098c094e6dc1e8f53b7be 550 Gene3D G3DSA:2.60.40.420 183 367 5.1E-31 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS01810 5dca0f6bd53098c094e6dc1e8f53b7be 550 SUPERFAMILY SSF49503 79 187 2.48E-29 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS01810 5dca0f6bd53098c094e6dc1e8f53b7be 550 ProSitePatterns PS00080 Multicopper oxidases signature 2. 532 543 - T 28-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 MKLM6_RS01810 5dca0f6bd53098c094e6dc1e8f53b7be 550 SUPERFAMILY SSF49503 189 306 9.81E-26 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS01810 5dca0f6bd53098c094e6dc1e8f53b7be 550 Pfam PF07732 Multicopper oxidase 71 184 3.2E-27 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 MKLM6_RS01810 5dca0f6bd53098c094e6dc1e8f53b7be 550 Gene3D G3DSA:2.60.40.420 370 550 2.7E-27 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS01810 5dca0f6bd53098c094e6dc1e8f53b7be 550 Gene3D G3DSA:2.60.40.420 35 182 2.9E-27 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS01810 5dca0f6bd53098c094e6dc1e8f53b7be 550 Pfam PF07731 Multicopper oxidase 465 549 2.1E-19 T 28-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 MKLM6_RS01810 5dca0f6bd53098c094e6dc1e8f53b7be 550 SUPERFAMILY SSF49503 466 549 7.94E-22 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS01810 5dca0f6bd53098c094e6dc1e8f53b7be 550 SUPERFAMILY SSF49503 395 427 7.94E-22 T 28-03-2018 IPR008972 Cupredoxin MKLM6_RS13755 9ced437527e7abb39d109985426b2b54 103 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 67 83 1.9E-16 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 MKLM6_RS13755 9ced437527e7abb39d109985426b2b54 103 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 32 48 1.9E-16 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 MKLM6_RS13755 9ced437527e7abb39d109985426b2b54 103 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 88 101 1.9E-16 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 MKLM6_RS13755 9ced437527e7abb39d109985426b2b54 103 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 6 102 2.5E-26 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 MKLM6_RS13755 9ced437527e7abb39d109985426b2b54 103 Pfam PF02049 Flagellar hook-basal body complex protein FliE 20 103 6.4E-31 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 MKLM6_RS13755 9ced437527e7abb39d109985426b2b54 103 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 2 103 18.374 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 MKLM6_RS00395 f7aa96a7a788dbc1254579e744aa4257 140 Gene3D G3DSA:1.10.1660.10 55 129 7.9E-9 T 28-03-2018 MKLM6_RS00395 f7aa96a7a788dbc1254579e744aa4257 140 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 8.6E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MKLM6_RS00395 f7aa96a7a788dbc1254579e744aa4257 140 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 8.6E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MKLM6_RS00395 f7aa96a7a788dbc1254579e744aa4257 140 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 8.6E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MKLM6_RS00395 f7aa96a7a788dbc1254579e744aa4257 140 SUPERFAMILY SSF46955 1 119 2.01E-22 T 28-03-2018 IPR009061 Putative DNA-binding domain MKLM6_RS00395 f7aa96a7a788dbc1254579e744aa4257 140 Gene3D G3DSA:1.10.1660.10 1 54 3.4E-15 T 28-03-2018 MKLM6_RS00395 f7aa96a7a788dbc1254579e744aa4257 140 Pfam PF13411 MerR HTH family regulatory protein 1 68 8.3E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MKLM6_RS00395 f7aa96a7a788dbc1254579e744aa4257 140 SMART SM00422 1 69 8.8E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MKLM6_RS08685 8dfc3ea1fae39375a254a47ce0f90d14 131 Gene3D G3DSA:1.20.120.50 1 131 1.5E-30 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 MKLM6_RS08685 8dfc3ea1fae39375a254a47ce0f90d14 131 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 9 129 1.1E-29 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 MKLM6_RS08685 8dfc3ea1fae39375a254a47ce0f90d14 131 ProSitePatterns PS00550 Hemerythrin family signature. 59 82 - T 28-03-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 MKLM6_RS08685 8dfc3ea1fae39375a254a47ce0f90d14 131 Pfam PF01814 Hemerythrin HHE cation binding domain 18 124 5.2E-11 T 28-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 MKLM6_RS08685 8dfc3ea1fae39375a254a47ce0f90d14 131 SUPERFAMILY SSF47188 1 130 2.75E-28 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 MKLM6_RS19355 b8afd49272460107bea0d0671b6f1050 172 Gene3D G3DSA:3.30.420.10 5 163 1.3E-11 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS19355 b8afd49272460107bea0d0671b6f1050 172 SUPERFAMILY SSF53098 8 159 3.13E-16 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS00805 8f1b05eec7065ad5a89393d29de94a61 167 Gene3D G3DSA:1.10.490.10 1 166 1.9E-27 T 28-03-2018 MKLM6_RS00805 8f1b05eec7065ad5a89393d29de94a61 167 SUPERFAMILY SSF46458 9 61 3.1E-6 T 28-03-2018 IPR009050 Globin-like MKLM6_RS00805 8f1b05eec7065ad5a89393d29de94a61 167 SUPERFAMILY SSF46458 106 150 3.1E-6 T 28-03-2018 IPR009050 Globin-like MKLM6_RS20800 787f36592f5351cc0a46865000e4d774 146 SUPERFAMILY SSF54593 1 128 1.34E-32 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MKLM6_RS20800 787f36592f5351cc0a46865000e4d774 146 Gene3D G3DSA:3.10.180.10 1 144 8.2E-31 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MKLM6_RS20800 787f36592f5351cc0a46865000e4d774 146 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 124 5.2E-16 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MKLM6_RS09300 74cdb95b4a787b295bcdceb6b5bf4c46 290 SUPERFAMILY SSF53335 241 272 1.25E-14 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS09300 74cdb95b4a787b295bcdceb6b5bf4c46 290 SUPERFAMILY SSF53335 121 204 1.25E-14 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS09300 74cdb95b4a787b295bcdceb6b5bf4c46 290 Gene3D G3DSA:3.40.50.150 69 273 5.4E-12 T 28-03-2018 MKLM6_RS09300 74cdb95b4a787b295bcdceb6b5bf4c46 290 Pfam PF08241 Methyltransferase domain 121 167 1.1E-7 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MKLM6_RS00220 2915a0739e4a0f5bca5a01d258560c2d 286 Gene3D G3DSA:3.40.1360.10 195 284 6.3E-6 T 28-03-2018 MKLM6_RS00220 2915a0739e4a0f5bca5a01d258560c2d 286 Pfam PF13662 Toprim domain 201 272 2.7E-10 T 28-03-2018 IPR006171 TOPRIM domain MKLM6_RS14885 557d04097d42cea9863d60248b4ad3f7 211 Gene3D G3DSA:3.40.50.620 1 207 4.8E-52 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS14885 557d04097d42cea9863d60248b4ad3f7 211 Pfam PF01467 Cytidylyltransferase-like 4 179 3.1E-25 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MKLM6_RS14885 557d04097d42cea9863d60248b4ad3f7 211 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 2 64 4.1E-12 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MKLM6_RS14885 557d04097d42cea9863d60248b4ad3f7 211 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 4 205 1.5E-43 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MKLM6_RS14885 557d04097d42cea9863d60248b4ad3f7 211 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 1 206 27.204 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MKLM6_RS14885 557d04097d42cea9863d60248b4ad3f7 211 SUPERFAMILY SSF52374 1 207 3.44E-51 T 28-03-2018 MKLM6_RS00560 8936f60d637d70c329a657105922b989 510 Gene3D G3DSA:2.60.40.10 50 135 2.8E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS00560 8936f60d637d70c329a657105922b989 510 Pfam PF06672 Protein of unknown function (DUF1175) 291 506 8.0E-58 T 28-03-2018 IPR009558 Protein of unknown function DUF1175 MKLM6_RS00560 8936f60d637d70c329a657105922b989 510 Pfam PF09906 Uncharacterized protein conserved in bacteria (DUF2135) 204 245 4.4E-5 T 28-03-2018 IPR019220 Domain of unknown function DUF2135 MKLM6_RS00560 8936f60d637d70c329a657105922b989 510 Gene3D G3DSA:3.90.1720.10 212 484 8.3E-7 T 28-03-2018 MKLM6_RS06625 03be8d7a62334c4689951354fc5cf480 85 Pfam PF13711 Domain of unknown function (DUF4160) 9 70 1.3E-22 T 28-03-2018 IPR025427 Protein of unknown function DUF4160 MKLM6_RS10840 4429260418fbfc87d40f6ab888584b73 364 Gene3D G3DSA:2.40.50.100 159 342 2.9E-4 T 28-03-2018 MKLM6_RS10840 4429260418fbfc87d40f6ab888584b73 364 Gene3D G3DSA:3.90.1170.30 35 112 7.1E-5 T 28-03-2018 MKLM6_RS10840 4429260418fbfc87d40f6ab888584b73 364 Gene3D G3DSA:1.10.287.470 113 158 1.3E-8 T 28-03-2018 MKLM6_RS10840 4429260418fbfc87d40f6ab888584b73 364 SUPERFAMILY SSF111369 58 274 1.44E-45 T 28-03-2018 MKLM6_RS10840 4429260418fbfc87d40f6ab888584b73 364 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 70 267 6.5E-31 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MKLM6_RS10840 4429260418fbfc87d40f6ab888584b73 364 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 42 351 5.0E-82 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MKLM6_RS21745 cd60e7c247d345ea31c00d588a80dad6 136 SUPERFAMILY SSF81593 3 125 1.18E-42 T 28-03-2018 MKLM6_RS21745 cd60e7c247d345ea31c00d588a80dad6 136 Pfam PF08780 Nucleotidyltransferase substrate binding protein like 9 129 5.8E-42 T 28-03-2018 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 MKLM6_RS21745 cd60e7c247d345ea31c00d588a80dad6 136 Gene3D G3DSA:1.20.120.330 2 133 2.6E-34 T 28-03-2018 MKLM6_RS21745 cd60e7c247d345ea31c00d588a80dad6 136 TIGRFAM TIGR01987 HI0074: nucleotidyltransferase substrate binding protein, HI0074 family 10 129 3.3E-28 T 28-03-2018 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 MKLM6_RS05370 611d72b09b75f5937905101d1df62dea 240 Pfam PF08241 Methyltransferase domain 60 157 6.1E-24 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MKLM6_RS05370 611d72b09b75f5937905101d1df62dea 240 Gene3D G3DSA:3.40.50.150 11 240 2.0E-29 T 28-03-2018 MKLM6_RS05370 611d72b09b75f5937905101d1df62dea 240 SUPERFAMILY SSF53335 30 207 1.52E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS04650 27599cd02bfc49fc056a5268f860a0dd 437 SUPERFAMILY SSF56112 4 266 9.58E-79 T 28-03-2018 IPR011009 Protein kinase-like domain MKLM6_RS04650 27599cd02bfc49fc056a5268f860a0dd 437 SMART SM00220 7 265 1.8E-66 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MKLM6_RS04650 27599cd02bfc49fc056a5268f860a0dd 437 PIRSF PIRSF000654 5 276 4.1E-33 T 28-03-2018 MKLM6_RS04650 27599cd02bfc49fc056a5268f860a0dd 437 Gene3D G3DSA:3.30.200.20 1 103 2.7E-23 T 28-03-2018 MKLM6_RS04650 27599cd02bfc49fc056a5268f860a0dd 437 Gene3D G3DSA:1.10.510.10 104 290 1.1E-52 T 28-03-2018 MKLM6_RS04650 27599cd02bfc49fc056a5268f860a0dd 437 Pfam PF00069 Protein kinase domain 7 259 3.0E-57 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MKLM6_RS04650 27599cd02bfc49fc056a5268f860a0dd 437 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 13 36 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 MKLM6_RS04650 27599cd02bfc49fc056a5268f860a0dd 437 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 127 139 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MKLM6_RS15785 0fbd49b685577bcf4e89b2e2d8b6aec8 190 Gene3D G3DSA:2.60.120.10 2 188 3.6E-61 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS15785 0fbd49b685577bcf4e89b2e2d8b6aec8 190 SUPERFAMILY SSF51182 8 183 4.3E-60 T 28-03-2018 IPR011051 RmlC-like cupin domain MKLM6_RS15785 0fbd49b685577bcf4e89b2e2d8b6aec8 190 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 10 182 2.1E-46 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MKLM6_RS15785 0fbd49b685577bcf4e89b2e2d8b6aec8 190 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 13 182 7.3E-58 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MKLM6_RS15785 0fbd49b685577bcf4e89b2e2d8b6aec8 190 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 7 179 6.0E-57 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MKLM6_RS13100 7a0548e93ee2805983e884ff9461cbd9 238 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 7 237 1.7E-92 T 28-03-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS13100 7a0548e93ee2805983e884ff9461cbd9 238 SUPERFAMILY SSF53098 7 180 5.18E-55 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS13100 7a0548e93ee2805983e884ff9461cbd9 238 SMART SM00479 7 180 1.8E-48 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MKLM6_RS13100 7a0548e93ee2805983e884ff9461cbd9 238 Gene3D G3DSA:3.30.420.10 2 181 8.8E-40 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS13100 7a0548e93ee2805983e884ff9461cbd9 238 Pfam PF00929 Exonuclease 9 171 3.9E-39 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MKLM6_RS13100 7a0548e93ee2805983e884ff9461cbd9 238 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 8 219 2.2E-68 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS20410 4e4c9ce427c3497fab38238a5074b58c 190 Pfam PF05137 Fimbrial assembly protein (PilN) 100 176 2.3E-19 T 28-03-2018 IPR007813 Fimbrial assembly PilN MKLM6_RS00360 eb99a8f7cfbd26d158226d700fad605f 243 Pfam PF04402 Protein of unknown function (DUF541) 32 238 4.0E-22 T 28-03-2018 IPR007497 Protein of unknown function DUF541 MKLM6_RS00315 720c3915e75e7b1ce9ccb04bfd291119 299 SUPERFAMILY SSF53335 62 214 1.38E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS00315 720c3915e75e7b1ce9ccb04bfd291119 299 Pfam PF13489 Methyltransferase domain 64 206 7.3E-19 T 28-03-2018 MKLM6_RS00315 720c3915e75e7b1ce9ccb04bfd291119 299 Gene3D G3DSA:3.40.50.150 29 291 5.4E-20 T 28-03-2018 MKLM6_RS03860 2a818ea46c2e05381a84a6b44a61706e 249 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 36.169 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS03860 2a818ea46c2e05381a84a6b44a61706e 249 Gene3D G3DSA:3.30.70.980 84 179 9.3E-34 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS03860 2a818ea46c2e05381a84a6b44a61706e 249 Gene3D G3DSA:1.10.10.200 1 79 3.8E-29 T 28-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like MKLM6_RS03860 2a818ea46c2e05381a84a6b44a61706e 249 SUPERFAMILY SSF75625 3 246 2.75E-95 T 28-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS03860 2a818ea46c2e05381a84a6b44a61706e 249 Pfam PF01709 Transcriptional regulator 5 238 3.4E-97 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS03860 2a818ea46c2e05381a84a6b44a61706e 249 Gene3D G3DSA:3.30.70.980 180 249 2.3E-12 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS03860 2a818ea46c2e05381a84a6b44a61706e 249 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 2.3E-98 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS03785 008daccd6fb720c56e6b37db7b654415 159 Pfam PF13404 AsnC-type helix-turn-helix domain 3 47 3.5E-7 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MKLM6_RS03785 008daccd6fb720c56e6b37db7b654415 159 SMART SM00344 3 115 0.0021 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MKLM6_RS03785 008daccd6fb720c56e6b37db7b654415 159 Gene3D G3DSA:3.30.70.920 56 157 3.6E-14 T 28-03-2018 MKLM6_RS03785 008daccd6fb720c56e6b37db7b654415 159 SUPERFAMILY SSF46785 3 66 9.91E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS03785 008daccd6fb720c56e6b37db7b654415 159 Gene3D G3DSA:1.10.10.10 1 55 1.6E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS08220 92a787881204b4d8d736922357cb071b 319 SUPERFAMILY SSF63829 39 313 2.62E-51 T 28-03-2018 MKLM6_RS08220 92a787881204b4d8d736922357cb071b 319 Gene3D G3DSA:2.120.10.30 53 310 5.5E-30 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MKLM6_RS08220 92a787881204b4d8d736922357cb071b 319 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 50 299 1.4E-40 T 28-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region MKLM6_RS19350 71f90e9e601c8c27b67610f46779983c 788 PIRSF PIRSF017245 1 788 0.0 T 28-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 MKLM6_RS19350 71f90e9e601c8c27b67610f46779983c 788 SUPERFAMILY SSF52922 598 729 2.82E-6 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MKLM6_RS19350 71f90e9e601c8c27b67610f46779983c 788 SUPERFAMILY SSF52518 375 588 5.12E-24 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS19350 71f90e9e601c8c27b67610f46779983c 788 Gene3D G3DSA:3.40.50.970 384 601 8.8E-35 T 28-03-2018 MKLM6_RS19350 71f90e9e601c8c27b67610f46779983c 788 Pfam PF09364 XFP N-terminal domain 7 383 1.7E-192 T 28-03-2018 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal MKLM6_RS19350 71f90e9e601c8c27b67610f46779983c 788 Pfam PF09363 XFP C-terminal domain 586 787 5.8E-88 T 28-03-2018 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 MKLM6_RS19350 71f90e9e601c8c27b67610f46779983c 788 Gene3D G3DSA:3.40.50.920 606 788 1.1E-77 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MKLM6_RS19350 71f90e9e601c8c27b67610f46779983c 788 ProSitePatterns PS60003 Phosphoketolase signature 2. 156 174 - T 28-03-2018 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 MKLM6_RS19350 71f90e9e601c8c27b67610f46779983c 788 Hamap MF_01403 Probable phosphoketolase. 4 788 40.2 T 28-03-2018 IPR023962 Probable phosphoketolase MKLM6_RS19350 71f90e9e601c8c27b67610f46779983c 788 SUPERFAMILY SSF52518 6 367 1.37E-75 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS19350 71f90e9e601c8c27b67610f46779983c 788 ProSitePatterns PS60002 Phosphoketolase signature 1. 143 149 - T 28-03-2018 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 MKLM6_RS19350 71f90e9e601c8c27b67610f46779983c 788 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 398 575 6.1E-83 T 28-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 MKLM6_RS19350 71f90e9e601c8c27b67610f46779983c 788 Gene3D G3DSA:3.40.50.970 1 377 1.4E-90 T 28-03-2018 MKLM6_RS04605 ee71c5aab7fdaebedd3f39220321c9e8 433 SMART SM00994 5 44 3.3E-9 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 MKLM6_RS04605 ee71c5aab7fdaebedd3f39220321c9e8 433 SMART SM01086 320 414 9.0E-32 T 28-03-2018 IPR019489 Clp ATPase, C-terminal MKLM6_RS04605 ee71c5aab7fdaebedd3f39220321c9e8 433 Gene3D G3DSA:3.40.50.300 50 318 1.5E-58 T 28-03-2018 MKLM6_RS04605 ee71c5aab7fdaebedd3f39220321c9e8 433 SUPERFAMILY SSF52540 54 400 9.46E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS04605 ee71c5aab7fdaebedd3f39220321c9e8 433 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 3 410 1.0E-157 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 MKLM6_RS04605 ee71c5aab7fdaebedd3f39220321c9e8 433 SMART SM00382 112 266 7.3E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS04605 ee71c5aab7fdaebedd3f39220321c9e8 433 SUPERFAMILY SSF57716 7 41 2.99E-6 T 28-03-2018 MKLM6_RS04605 ee71c5aab7fdaebedd3f39220321c9e8 433 Pfam PF06689 ClpX C4-type zinc finger 6 41 5.2E-10 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 MKLM6_RS04605 ee71c5aab7fdaebedd3f39220321c9e8 433 Gene3D G3DSA:1.10.8.60 320 411 1.5E-32 T 28-03-2018 MKLM6_RS04605 ee71c5aab7fdaebedd3f39220321c9e8 433 Pfam PF07724 AAA domain (Cdc48 subfamily) 113 313 2.6E-42 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MKLM6_RS04605 ee71c5aab7fdaebedd3f39220321c9e8 433 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 320 397 2.4E-14 T 28-03-2018 IPR019489 Clp ATPase, C-terminal MKLM6_RS04605 ee71c5aab7fdaebedd3f39220321c9e8 433 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 418 46.782 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 MKLM6_RS09610 c3080807f167c8cbecc14f4a6f2e1ed9 52 Pfam PF11752 Protein of unknown function (DUF3309) 4 52 1.3E-21 T 28-03-2018 IPR021738 Protein of unknown function DUF3309 MKLM6_RS18140 a2ac2b5d5daf1a0d88f72bb954c337fd 70 SMART SM00357 6 70 5.6E-23 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 MKLM6_RS18140 a2ac2b5d5daf1a0d88f72bb954c337fd 70 SUPERFAMILY SSF50249 5 69 2.29E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS18140 a2ac2b5d5daf1a0d88f72bb954c337fd 70 Pfam PF00313 'Cold-shock' DNA-binding domain 6 69 4.2E-26 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MKLM6_RS18140 a2ac2b5d5daf1a0d88f72bb954c337fd 70 PRINTS PR00050 Cold shock protein signature 7 22 1.5E-15 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MKLM6_RS18140 a2ac2b5d5daf1a0d88f72bb954c337fd 70 PRINTS PR00050 Cold shock protein signature 43 61 1.5E-15 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MKLM6_RS18140 a2ac2b5d5daf1a0d88f72bb954c337fd 70 PRINTS PR00050 Cold shock protein signature 27 36 1.5E-15 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MKLM6_RS18140 a2ac2b5d5daf1a0d88f72bb954c337fd 70 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 36 - T 28-03-2018 IPR019844 Cold-shock conserved site MKLM6_RS18140 a2ac2b5d5daf1a0d88f72bb954c337fd 70 Gene3D G3DSA:2.40.50.140 4 70 1.1E-24 T 28-03-2018 MKLM6_RS18140 a2ac2b5d5daf1a0d88f72bb954c337fd 70 PIRSF PIRSF002599 1 70 1.9E-21 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 MKLM6_RS07415 15ad1fa4cf17b1fbb94a2cfc0b6576e5 276 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 25 224 9.9E-39 T 28-03-2018 MKLM6_RS01030 5e628ed42146ee4217f839b5411c1e6d 210 Pfam PF07238 PilZ domain 109 193 2.6E-5 T 28-03-2018 IPR009875 PilZ domain GO:0035438 MKLM6_RS01030 5e628ed42146ee4217f839b5411c1e6d 210 Gene3D G3DSA:2.40.10.220 108 197 1.1E-9 T 28-03-2018 MKLM6_RS01030 5e628ed42146ee4217f839b5411c1e6d 210 Gene3D G3DSA:2.40.10.220 7 107 4.4E-6 T 28-03-2018 MKLM6_RS01030 5e628ed42146ee4217f839b5411c1e6d 210 SUPERFAMILY SSF141371 109 196 5.89E-8 T 28-03-2018 MKLM6_RS00345 fdcea73f2adbda8a39f6db8703405436 100 Pfam PF14333 Domain of unknown function (DUF4389) 13 86 5.5E-27 T 28-03-2018 IPR025498 Protein of unknown function DUF4389 MKLM6_RS19245 625db78a9a47901abe24efd1471cb3c1 84 SUPERFAMILY SSF143120 1 70 7.46E-8 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MKLM6_RS19245 625db78a9a47901abe24efd1471cb3c1 84 Gene3D G3DSA:3.40.1620.10 1 59 2.6E-4 T 28-03-2018 MKLM6_RS16520 05679325f767139820befc0ece3e379a 841 Gene3D G3DSA:3.60.10.10 460 775 4.6E-30 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MKLM6_RS16520 05679325f767139820befc0ece3e379a 841 SUPERFAMILY SSF63446 775 834 1.03E-5 T 28-03-2018 IPR016134 Dockerin domain GO:0000272 MKLM6_RS16520 05679325f767139820befc0ece3e379a 841 Gene3D G3DSA:2.60.40.1260 14 132 0.0012 T 28-03-2018 IPR001322 Lamin Tail Domain MKLM6_RS16520 05679325f767139820befc0ece3e379a 841 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 463 767 1.0E-6 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MKLM6_RS16520 05679325f767139820befc0ece3e379a 841 SUPERFAMILY SSF56219 439 718 2.3E-35 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MKLM6_RS16520 05679325f767139820befc0ece3e379a 841 SUPERFAMILY SSF56219 749 777 2.3E-35 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MKLM6_RS01720 6f58901ea55a9dd4cdf21324cccbae4e 78 Gene3D G3DSA:3.40.30.10 1 72 1.9E-8 T 28-03-2018 MKLM6_RS01720 6f58901ea55a9dd4cdf21324cccbae4e 78 Pfam PF05768 Glutaredoxin-like domain (DUF836) 5 68 1.4E-12 T 28-03-2018 IPR008554 Glutaredoxin-like MKLM6_RS01720 6f58901ea55a9dd4cdf21324cccbae4e 78 SUPERFAMILY SSF52833 4 71 3.12E-13 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS05940 4b7b1ae4fb348aefc89541407a67bf42 367 Gene3D G3DSA:3.30.1950.10 88 158 5.5E-18 T 28-03-2018 MKLM6_RS05940 4b7b1ae4fb348aefc89541407a67bf42 367 Pfam PF10531 SLBB domain 171 218 1.7E-9 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS05940 4b7b1ae4fb348aefc89541407a67bf42 367 Gene3D G3DSA:3.10.560.10 248 337 2.6E-12 T 28-03-2018 MKLM6_RS05940 4b7b1ae4fb348aefc89541407a67bf42 367 Gene3D G3DSA:3.10.560.10 159 247 4.4E-21 T 28-03-2018 MKLM6_RS05940 4b7b1ae4fb348aefc89541407a67bf42 367 Pfam PF02563 Polysaccharide biosynthesis/export protein 79 163 5.5E-26 T 28-03-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 MKLM6_RS02615 93c984f4d4ddf214e55bdea65c59dc93 679 Gene3D G3DSA:1.10.1370.10 140 439 8.2E-57 T 28-03-2018 MKLM6_RS02615 93c984f4d4ddf214e55bdea65c59dc93 679 Gene3D G3DSA:1.10.1370.10 456 679 1.1E-66 T 28-03-2018 MKLM6_RS02615 93c984f4d4ddf214e55bdea65c59dc93 679 SUPERFAMILY SSF55486 1 676 2.83E-204 T 28-03-2018 MKLM6_RS02615 93c984f4d4ddf214e55bdea65c59dc93 679 Gene3D G3DSA:1.20.1050.40 4 138 4.2E-36 T 28-03-2018 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal MKLM6_RS02615 93c984f4d4ddf214e55bdea65c59dc93 679 Pfam PF01432 Peptidase family M3 222 676 1.1E-155 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 MKLM6_RS19320 43de392e38f218cc9ec63b4d95c61d85 91 Pfam PF00374 Nickel-dependent hydrogenase 7 48 1.6E-7 T 28-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 MKLM6_RS19320 43de392e38f218cc9ec63b4d95c61d85 91 SUPERFAMILY SSF56762 8 83 6.41E-17 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS19320 43de392e38f218cc9ec63b4d95c61d85 91 Gene3D G3DSA:1.10.645.10 4 86 2.1E-16 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS17955 4196f28adbc6cee85a9b3113bfcc9285 574 PRINTS PR01900 YidC translocation/secretion protein signature 517 541 7.2E-23 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MKLM6_RS17955 4196f28adbc6cee85a9b3113bfcc9285 574 PRINTS PR01900 YidC translocation/secretion protein signature 369 385 7.2E-23 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MKLM6_RS17955 4196f28adbc6cee85a9b3113bfcc9285 574 PRINTS PR01900 YidC translocation/secretion protein signature 498 513 7.2E-23 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MKLM6_RS17955 4196f28adbc6cee85a9b3113bfcc9285 574 PRINTS PR00701 60kDa inner membrane protein signature 2 23 3.0E-65 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MKLM6_RS17955 4196f28adbc6cee85a9b3113bfcc9285 574 PRINTS PR00701 60kDa inner membrane protein signature 354 374 3.0E-65 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MKLM6_RS17955 4196f28adbc6cee85a9b3113bfcc9285 574 PRINTS PR00701 60kDa inner membrane protein signature 445 468 3.0E-65 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MKLM6_RS17955 4196f28adbc6cee85a9b3113bfcc9285 574 PRINTS PR00701 60kDa inner membrane protein signature 188 208 3.0E-65 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MKLM6_RS17955 4196f28adbc6cee85a9b3113bfcc9285 574 PRINTS PR00701 60kDa inner membrane protein signature 281 296 3.0E-65 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MKLM6_RS17955 4196f28adbc6cee85a9b3113bfcc9285 574 PRINTS PR00701 60kDa inner membrane protein signature 528 551 3.0E-65 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MKLM6_RS17955 4196f28adbc6cee85a9b3113bfcc9285 574 PRINTS PR00701 60kDa inner membrane protein signature 492 514 3.0E-65 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MKLM6_RS17955 4196f28adbc6cee85a9b3113bfcc9285 574 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 564 23.533 T 28-03-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0051205 MKLM6_RS17955 4196f28adbc6cee85a9b3113bfcc9285 574 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 4 104 5.8E-19 T 28-03-2018 IPR028053 Membrane insertase YidC, N-terminal MKLM6_RS17955 4196f28adbc6cee85a9b3113bfcc9285 574 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 122 382 9.6E-85 T 28-03-2018 IPR028053 Membrane insertase YidC, N-terminal MKLM6_RS17955 4196f28adbc6cee85a9b3113bfcc9285 574 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 383 562 3.1E-66 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal MKLM6_RS17955 4196f28adbc6cee85a9b3113bfcc9285 574 Pfam PF02096 60Kd inner membrane protein 384 562 9.5E-59 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MKLM6_RS17955 4196f28adbc6cee85a9b3113bfcc9285 574 Pfam PF14849 YidC periplasmic domain 74 373 1.9E-79 T 28-03-2018 IPR028053 Membrane insertase YidC, N-terminal MKLM6_RS01365 533a8faa77bff894d1cac762e4533dfc 262 SUPERFAMILY SSF74653 173 253 4.97E-24 T 28-03-2018 MKLM6_RS01365 533a8faa77bff894d1cac762e4533dfc 262 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 177 255 1.2E-22 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 MKLM6_RS01365 533a8faa77bff894d1cac762e4533dfc 262 PRINTS PR01374 Gram-negative bacterial tonB protein signature 194 212 3.2E-6 T 28-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 MKLM6_RS01365 533a8faa77bff894d1cac762e4533dfc 262 PRINTS PR01374 Gram-negative bacterial tonB protein signature 173 194 3.2E-6 T 28-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 MKLM6_RS01365 533a8faa77bff894d1cac762e4533dfc 262 PRINTS PR01374 Gram-negative bacterial tonB protein signature 108 118 3.2E-6 T 28-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 MKLM6_RS01365 533a8faa77bff894d1cac762e4533dfc 262 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 179 255 2.4E-22 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 MKLM6_RS01365 533a8faa77bff894d1cac762e4533dfc 262 Gene3D G3DSA:3.30.1150.10 85 259 2.6E-26 T 28-03-2018 MKLM6_RS11070 73d87862b9a05f675e644a2f7826fad5 256 PIRSF PIRSF004846 1 254 1.9E-55 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 MKLM6_RS11070 73d87862b9a05f675e644a2f7826fad5 256 Gene3D G3DSA:3.40.190.10 25 118 2.2E-13 T 28-03-2018 MKLM6_RS11070 73d87862b9a05f675e644a2f7826fad5 256 Gene3D G3DSA:3.40.190.10 119 212 5.1E-29 T 28-03-2018 MKLM6_RS11070 73d87862b9a05f675e644a2f7826fad5 256 SUPERFAMILY SSF53850 30 253 5.67E-64 T 28-03-2018 MKLM6_RS11070 73d87862b9a05f675e644a2f7826fad5 256 Pfam PF13531 Bacterial extracellular solute-binding protein 30 250 6.8E-46 T 28-03-2018 MKLM6_RS11070 73d87862b9a05f675e644a2f7826fad5 256 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 32 249 1.2E-76 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 MKLM6_RS12615 a790992ca37d13eb0eef75960f37d5f6 84 Gene3D G3DSA:3.40.30.10 1 84 3.3E-28 T 28-03-2018 MKLM6_RS12615 a790992ca37d13eb0eef75960f37d5f6 84 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 4 82 4.0E-35 T 28-03-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 MKLM6_RS12615 a790992ca37d13eb0eef75960f37d5f6 84 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 28-03-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 MKLM6_RS12615 a790992ca37d13eb0eef75960f37d5f6 84 Pfam PF00462 Glutaredoxin 4 63 8.8E-23 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 MKLM6_RS12615 a790992ca37d13eb0eef75960f37d5f6 84 PRINTS PR00160 Glutaredoxin signature 4 22 1.1E-14 T 28-03-2018 IPR014025 Glutaredoxin subgroup MKLM6_RS12615 a790992ca37d13eb0eef75960f37d5f6 84 PRINTS PR00160 Glutaredoxin signature 46 59 1.1E-14 T 28-03-2018 IPR014025 Glutaredoxin subgroup MKLM6_RS12615 a790992ca37d13eb0eef75960f37d5f6 84 PRINTS PR00160 Glutaredoxin signature 60 73 1.1E-14 T 28-03-2018 IPR014025 Glutaredoxin subgroup MKLM6_RS12615 a790992ca37d13eb0eef75960f37d5f6 84 SUPERFAMILY SSF52833 2 83 7.31E-29 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS18845 1387d5c915a6e11de0b53dd5db882f80 325 SUPERFAMILY SSF53955 11 322 1.45E-88 T 28-03-2018 IPR023346 Lysozyme-like domain MKLM6_RS18845 1387d5c915a6e11de0b53dd5db882f80 325 Pfam PF13406 Transglycosylase SLT domain 30 318 5.3E-102 T 28-03-2018 IPR031304 Transglycosylase SLT domain 2 MKLM6_RS18845 1387d5c915a6e11de0b53dd5db882f80 325 TIGRFAM TIGR02282 MltB: lytic murein transglycosylase B 32 320 5.2E-112 T 28-03-2018 IPR011757 Lytic transglycosylase MltB MKLM6_RS18845 1387d5c915a6e11de0b53dd5db882f80 325 Gene3D G3DSA:1.10.8.350 24 90 0.0029 T 28-03-2018 MKLM6_RS18845 1387d5c915a6e11de0b53dd5db882f80 325 Gene3D G3DSA:1.10.8.350 91 195 1.7E-37 T 28-03-2018 MKLM6_RS18845 1387d5c915a6e11de0b53dd5db882f80 325 Gene3D G3DSA:1.10.530.10 200 325 8.4E-34 T 28-03-2018 MKLM6_RS12680 2ab8592711cfae188af51e1f5df1637e 188 Pfam PF00857 Isochorismatase family 13 165 4.7E-31 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 MKLM6_RS12680 2ab8592711cfae188af51e1f5df1637e 188 Gene3D G3DSA:3.40.50.850 1 188 8.0E-41 T 28-03-2018 MKLM6_RS12680 2ab8592711cfae188af51e1f5df1637e 188 SUPERFAMILY SSF52499 1 187 4.19E-47 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 MKLM6_RS06575 c39da32837b8f87ea07f1eed30324e07 535 Pfam PF00672 HAMP domain 207 252 4.6E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS06575 c39da32837b8f87ea07f1eed30324e07 535 SMART SM00304 205 258 2.8E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS06575 c39da32837b8f87ea07f1eed30324e07 535 SUPERFAMILY SSF58104 226 535 4.45E-72 T 28-03-2018 MKLM6_RS06575 c39da32837b8f87ea07f1eed30324e07 535 SMART SM00283 273 534 7.8E-75 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS06575 c39da32837b8f87ea07f1eed30324e07 535 Gene3D G3DSA:1.10.287.950 179 297 1.9E-4 T 28-03-2018 MKLM6_RS06575 c39da32837b8f87ea07f1eed30324e07 535 Gene3D G3DSA:1.10.287.950 490 535 0.1 T 28-03-2018 MKLM6_RS06575 c39da32837b8f87ea07f1eed30324e07 535 Gene3D G3DSA:1.10.287.950 298 489 2.6E-48 T 28-03-2018 MKLM6_RS06575 c39da32837b8f87ea07f1eed30324e07 535 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 333 501 3.6E-43 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS06575 c39da32837b8f87ea07f1eed30324e07 535 Gene3D G3DSA:3.30.450.20 23 178 2.9E-4 T 28-03-2018 MKLM6_RS11470 40e2c9c3fc0a156b77f8cbc98dc59ec6 1057 SUPERFAMILY SSF48208 628 698 3.91E-11 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 MKLM6_RS11470 40e2c9c3fc0a156b77f8cbc98dc59ec6 1057 SUPERFAMILY SSF48208 742 958 3.91E-11 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 MKLM6_RS11470 40e2c9c3fc0a156b77f8cbc98dc59ec6 1057 SUPERFAMILY SSF48208 395 523 3.91E-11 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 MKLM6_RS11470 40e2c9c3fc0a156b77f8cbc98dc59ec6 1057 Gene3D G3DSA:2.70.98.40 90 311 3.3E-23 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 MKLM6_RS11470 40e2c9c3fc0a156b77f8cbc98dc59ec6 1057 Gene3D G3DSA:1.50.10.10 325 906 5.6E-18 T 28-03-2018 MKLM6_RS07905 e4796b05df5ab3948b9b91c8b4f008b4 489 SMART SM00849 283 468 7.5E-8 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS07905 e4796b05df5ab3948b9b91c8b4f008b4 489 Pfam PF00753 Metallo-beta-lactamase superfamily 281 353 2.5E-10 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS07905 e4796b05df5ab3948b9b91c8b4f008b4 489 SUPERFAMILY SSF56281 265 474 1.11E-28 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS07905 e4796b05df5ab3948b9b91c8b4f008b4 489 Gene3D G3DSA:3.60.15.10 263 488 1.3E-20 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS10090 37d18faec4ab8a60c344464f9d16402b 362 Pfam PF16074 Type IV Pilus-assembly protein W 235 360 5.9E-29 T 28-03-2018 IPR032092 Type IV Pilus-assembly protein W GO:0043683 MKLM6_RS10090 37d18faec4ab8a60c344464f9d16402b 362 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 18 38 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS10090 37d18faec4ab8a60c344464f9d16402b 362 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 17 38 6.4E-5 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS10090 37d18faec4ab8a60c344464f9d16402b 362 SUPERFAMILY SSF54523 21 111 5.49E-5 T 28-03-2018 MKLM6_RS10090 37d18faec4ab8a60c344464f9d16402b 362 Pfam PF07963 Prokaryotic N-terminal methylation motif 15 39 1.0E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS01105 11cfaf126755f93842cc310ebcdcf28b 170 Pfam PF04892 VanZ like family 74 157 7.3E-7 T 28-03-2018 IPR006976 VanZ-like MKLM6_RS03480 bb4706b41982f17bdb5e48779462e4e7 791 Pfam PF00593 TonB dependent receptor 312 774 1.9E-33 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS03480 bb4706b41982f17bdb5e48779462e4e7 791 SUPERFAMILY SSF56935 76 654 1.07E-109 T 28-03-2018 MKLM6_RS03480 bb4706b41982f17bdb5e48779462e4e7 791 SUPERFAMILY SSF56935 681 791 1.07E-109 T 28-03-2018 MKLM6_RS03480 bb4706b41982f17bdb5e48779462e4e7 791 Gene3D G3DSA:2.170.130.10 68 196 5.0E-24 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS03480 bb4706b41982f17bdb5e48779462e4e7 791 Gene3D G3DSA:2.40.170.20 197 791 3.4E-64 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS03480 bb4706b41982f17bdb5e48779462e4e7 791 Pfam PF07715 TonB-dependent Receptor Plug Domain 86 187 3.6E-17 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS21680 1143d140d6aecd1485f20149c58a7fbf 276 SUPERFAMILY SSF52499 6 72 1.7E-18 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 MKLM6_RS21680 1143d140d6aecd1485f20149c58a7fbf 276 SUPERFAMILY SSF52499 126 264 1.7E-18 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 MKLM6_RS21680 1143d140d6aecd1485f20149c58a7fbf 276 Gene3D G3DSA:3.40.50.850 2 273 3.9E-33 T 28-03-2018 MKLM6_RS21680 1143d140d6aecd1485f20149c58a7fbf 276 Pfam PF00857 Isochorismatase family 6 242 5.3E-5 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 MKLM6_RS12530 af57f629798826404e4bba1f8544bbde 105 Pfam PF00816 H-NS histone family 11 98 1.2E-23 T 28-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 MKLM6_RS12530 af57f629798826404e4bba1f8544bbde 105 Gene3D G3DSA:4.10.430.10 65 104 3.6E-16 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 MKLM6_RS12530 af57f629798826404e4bba1f8544bbde 105 SMART SM00528 59 104 1.6E-9 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 MKLM6_RS12530 af57f629798826404e4bba1f8544bbde 105 SUPERFAMILY SSF81273 63 104 3.41E-11 T 28-03-2018 MKLM6_RS15060 b8eb62b0a0d4561e2bf884ca0f7fc80f 164 Gene3D G3DSA:1.10.3420.10 44 148 7.4E-4 T 28-03-2018 MKLM6_RS15060 b8eb62b0a0d4561e2bf884ca0f7fc80f 164 Gene3D G3DSA:1.10.3420.10 1 43 0.2 T 28-03-2018 MKLM6_RS15540 8dbb991b7cf86b66e1dc0f00f1fa6fb7 134 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 133 1.6E-34 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 MKLM6_RS15540 8dbb991b7cf86b66e1dc0f00f1fa6fb7 134 Gene3D G3DSA:3.30.479.10 1 134 5.2E-34 T 28-03-2018 MKLM6_RS15540 8dbb991b7cf86b66e1dc0f00f1fa6fb7 134 PIRSF PIRSF006113 1 134 2.0E-21 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 MKLM6_RS15540 8dbb991b7cf86b66e1dc0f00f1fa6fb7 134 SUPERFAMILY SSF55620 1 132 7.78E-34 T 28-03-2018 MKLM6_RS03010 d2ccb3a79be9ab852d91ab15ce0bd58d 149 Pfam PF09424 Yqey-like protein 5 146 1.1E-55 T 28-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial MKLM6_RS03010 d2ccb3a79be9ab852d91ab15ce0bd58d 149 Gene3D G3DSA:1.10.10.410 92 147 2.9E-17 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal MKLM6_RS03010 d2ccb3a79be9ab852d91ab15ce0bd58d 149 SUPERFAMILY SSF89095 4 146 1.31E-42 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 MKLM6_RS03010 d2ccb3a79be9ab852d91ab15ce0bd58d 149 Gene3D G3DSA:1.10.1510.10 2 91 1.0E-30 T 28-03-2018 MKLM6_RS04030 859589834c65b4680d08121623fb88b4 213 Gene3D G3DSA:1.20.5.400 68 177 0.0014 T 28-03-2018 MKLM6_RS16840 da40cbfb393cd606095535fb3a529392 155 Hamap MF_00598 Protein Smg [smg]. 5 155 25.76 T 28-03-2018 IPR007456 Smg MKLM6_RS16840 da40cbfb393cd606095535fb3a529392 155 Pfam PF04361 Protein of unknown function (DUF494) 5 155 1.0E-50 T 28-03-2018 IPR007456 Smg MKLM6_RS03585 1e13a6fa25b0d415a203026cd835331e 409 SUPERFAMILY SSF53784 1 400 9.16E-78 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MKLM6_RS03585 1e13a6fa25b0d415a203026cd835331e 409 Gene3D G3DSA:3.40.50.450 1 260 4.3E-51 T 28-03-2018 MKLM6_RS03585 1e13a6fa25b0d415a203026cd835331e 409 Hamap MF_01977 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 3 400 65.287 T 28-03-2018 IPR011405 Pyrophosphate-dependent phosphofructokinase SMc01852 type GO:0006096|GO:0047334 KEGG: 00010+2.7.1.90|KEGG: 00030+2.7.1.90|KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042 MKLM6_RS03585 1e13a6fa25b0d415a203026cd835331e 409 Pfam PF00365 Phosphofructokinase 6 295 6.2E-37 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MKLM6_RS03585 1e13a6fa25b0d415a203026cd835331e 409 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 146 163 8.0E-16 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MKLM6_RS03585 1e13a6fa25b0d415a203026cd835331e 409 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 185 201 8.0E-16 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MKLM6_RS03585 1e13a6fa25b0d415a203026cd835331e 409 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 113 129 8.0E-16 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MKLM6_RS03585 1e13a6fa25b0d415a203026cd835331e 409 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 9 28 8.0E-16 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MKLM6_RS03585 1e13a6fa25b0d415a203026cd835331e 409 PIRSF PIRSF036484 1 406 3.3E-210 T 28-03-2018 IPR011405 Pyrophosphate-dependent phosphofructokinase SMc01852 type GO:0006096|GO:0047334 KEGG: 00010+2.7.1.90|KEGG: 00030+2.7.1.90|KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042 MKLM6_RS00575 5e389a0178be62f8436c6fc6667b4733 795 Pfam PF13654 AAA domain 27 535 8.6E-178 T 28-03-2018 MKLM6_RS00575 5e389a0178be62f8436c6fc6667b4733 795 Gene3D G3DSA:3.30.230.10 539 775 8.8E-32 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MKLM6_RS00575 5e389a0178be62f8436c6fc6667b4733 795 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 645 748 2.4E-12 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 MKLM6_RS00575 5e389a0178be62f8436c6fc6667b4733 795 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 561 577 1.9E-15 T 28-03-2018 MKLM6_RS00575 5e389a0178be62f8436c6fc6667b4733 795 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 672 691 1.9E-15 T 28-03-2018 MKLM6_RS00575 5e389a0178be62f8436c6fc6667b4733 795 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 642 661 1.9E-15 T 28-03-2018 MKLM6_RS00575 5e389a0178be62f8436c6fc6667b4733 795 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 57 76 1.9E-15 T 28-03-2018 MKLM6_RS00575 5e389a0178be62f8436c6fc6667b4733 795 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 702 720 1.9E-15 T 28-03-2018 MKLM6_RS00575 5e389a0178be62f8436c6fc6667b4733 795 SUPERFAMILY SSF54211 560 753 7.59E-37 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS00575 5e389a0178be62f8436c6fc6667b4733 795 SUPERFAMILY SSF52540 303 490 1.22E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS00575 5e389a0178be62f8436c6fc6667b4733 795 SUPERFAMILY SSF52540 27 86 1.22E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS20725 97b03ce06a456cf344e04ce04decbacd 538 SUPERFAMILY SSF56300 207 245 7.34E-8 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS20725 97b03ce06a456cf344e04ce04decbacd 538 SUPERFAMILY SSF56300 31 94 7.34E-8 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS20725 97b03ce06a456cf344e04ce04decbacd 538 SUPERFAMILY SSF56300 446 502 7.34E-8 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS20725 97b03ce06a456cf344e04ce04decbacd 538 SUPERFAMILY SSF56300 144 170 7.34E-8 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS20725 97b03ce06a456cf344e04ce04decbacd 538 Gene3D G3DSA:3.60.21.10 29 503 9.6E-15 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS16705 7743c42ae99157f5fd2f142784a90e13 719 Gene3D G3DSA:1.10.760.10 12 335 6.0E-27 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS16705 7743c42ae99157f5fd2f142784a90e13 719 Pfam PF03150 Di-haem cytochrome c peroxidase 17 343 1.1E-23 T 28-03-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 MKLM6_RS16705 7743c42ae99157f5fd2f142784a90e13 719 SUPERFAMILY SSF46626 577 666 8.54E-19 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS16705 7743c42ae99157f5fd2f142784a90e13 719 SUPERFAMILY SSF46626 362 447 8.54E-19 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS16705 7743c42ae99157f5fd2f142784a90e13 719 SUPERFAMILY SSF46626 16 61 6.26E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS16705 7743c42ae99157f5fd2f142784a90e13 719 SUPERFAMILY SSF46626 212 248 6.26E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS16705 7743c42ae99157f5fd2f142784a90e13 719 SUPERFAMILY SSF46626 154 174 6.26E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS16705 7743c42ae99157f5fd2f142784a90e13 719 Gene3D G3DSA:1.10.760.10 336 655 1.8E-30 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS01950 d585ecc63da7c785f2429a63e4caf921 218 Pfam PF00881 Nitroreductase family 20 184 5.0E-27 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MKLM6_RS01950 d585ecc63da7c785f2429a63e4caf921 218 Gene3D G3DSA:3.40.109.10 4 200 5.0E-39 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MKLM6_RS01950 d585ecc63da7c785f2429a63e4caf921 218 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 8 209 2.9E-74 T 28-03-2018 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5508|MetaCyc: PWY-5523 MKLM6_RS01950 d585ecc63da7c785f2429a63e4caf921 218 SUPERFAMILY SSF55469 14 215 1.3E-48 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MKLM6_RS18750 388fc300b7515a95b9d42db0271adefd 259 Pfam PF07238 PilZ domain 138 246 1.3E-7 T 28-03-2018 IPR009875 PilZ domain GO:0035438 MKLM6_RS18750 388fc300b7515a95b9d42db0271adefd 259 Pfam PF07317 Flagellar regulator YcgR 32 135 7.8E-18 T 28-03-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal MKLM6_RS18750 388fc300b7515a95b9d42db0271adefd 259 Gene3D G3DSA:2.30.110.10 31 136 1.5E-20 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MKLM6_RS18750 388fc300b7515a95b9d42db0271adefd 259 Gene3D G3DSA:2.40.10.220 137 259 4.9E-12 T 28-03-2018 MKLM6_RS18830 5996ab6ee7a6368a2f767d8b4875bae1 302 Pfam PF00700 Bacterial flagellin C-terminal helical region 219 301 3.2E-8 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MKLM6_RS18830 5996ab6ee7a6368a2f767d8b4875bae1 302 Gene3D G3DSA:1.20.1330.10 38 276 2.9E-34 T 28-03-2018 MKLM6_RS18830 5996ab6ee7a6368a2f767d8b4875bae1 302 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 185 1.3E-58 T 28-03-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 MKLM6_RS18830 5996ab6ee7a6368a2f767d8b4875bae1 302 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 139 2.1E-22 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MKLM6_RS18830 5996ab6ee7a6368a2f767d8b4875bae1 302 SUPERFAMILY SSF64518 1 301 1.31E-63 T 28-03-2018 MKLM6_RS13105 71d8ca3dab73c4f09f5b7e77b2533f2b 152 SUPERFAMILY SSF46785 2 131 9.92E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS13105 71d8ca3dab73c4f09f5b7e77b2533f2b 152 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 131 7.7E-32 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type MKLM6_RS13105 71d8ca3dab73c4f09f5b7e77b2533f2b 152 Gene3D G3DSA:1.10.10.10 1 142 1.4E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS13105 71d8ca3dab73c4f09f5b7e77b2533f2b 152 Pfam PF02082 Transcriptional regulator 1 82 2.0E-24 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type MKLM6_RS16470 f5a3c93ad7b10c04af7734aec9f9ecf9 862 PRINTS PR00985 Leucyl-tRNA synthetase signature 185 198 9.0E-53 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MKLM6_RS16470 f5a3c93ad7b10c04af7734aec9f9ecf9 862 PRINTS PR00985 Leucyl-tRNA synthetase signature 558 568 9.0E-53 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MKLM6_RS16470 f5a3c93ad7b10c04af7734aec9f9ecf9 862 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 169 9.0E-53 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MKLM6_RS16470 f5a3c93ad7b10c04af7734aec9f9ecf9 862 PRINTS PR00985 Leucyl-tRNA synthetase signature 127 144 9.0E-53 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MKLM6_RS16470 f5a3c93ad7b10c04af7734aec9f9ecf9 862 PRINTS PR00985 Leucyl-tRNA synthetase signature 487 505 9.0E-53 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MKLM6_RS16470 f5a3c93ad7b10c04af7734aec9f9ecf9 862 PRINTS PR00985 Leucyl-tRNA synthetase signature 215 234 9.0E-53 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MKLM6_RS16470 f5a3c93ad7b10c04af7734aec9f9ecf9 862 PRINTS PR00985 Leucyl-tRNA synthetase signature 525 547 9.0E-53 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MKLM6_RS16470 f5a3c93ad7b10c04af7734aec9f9ecf9 862 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 862 23.709 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MKLM6_RS16470 f5a3c93ad7b10c04af7734aec9f9ecf9 862 Gene3D G3DSA:3.40.50.620 404 649 1.0E-64 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS16470 f5a3c93ad7b10c04af7734aec9f9ecf9 862 Gene3D G3DSA:3.40.50.620 1 228 5.3E-82 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS16470 f5a3c93ad7b10c04af7734aec9f9ecf9 862 Gene3D G3DSA:1.10.730.10 650 799 4.9E-33 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS16470 f5a3c93ad7b10c04af7734aec9f9ecf9 862 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 5 862 0.0 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MKLM6_RS16470 f5a3c93ad7b10c04af7734aec9f9ecf9 862 Pfam PF08264 Anticodon-binding domain of tRNA 702 823 6.5E-19 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 MKLM6_RS16470 f5a3c93ad7b10c04af7734aec9f9ecf9 862 SUPERFAMILY SSF52374 416 669 8.34E-154 T 28-03-2018 MKLM6_RS16470 f5a3c93ad7b10c04af7734aec9f9ecf9 862 SUPERFAMILY SSF52374 4 226 8.34E-154 T 28-03-2018 MKLM6_RS16470 f5a3c93ad7b10c04af7734aec9f9ecf9 862 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 222 403 5.1E-76 T 28-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 MKLM6_RS16470 f5a3c93ad7b10c04af7734aec9f9ecf9 862 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS16470 f5a3c93ad7b10c04af7734aec9f9ecf9 862 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 418 573 3.3E-8 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS16470 f5a3c93ad7b10c04af7734aec9f9ecf9 862 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 171 6.3E-29 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS16470 f5a3c93ad7b10c04af7734aec9f9ecf9 862 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 620 658 1.7E-6 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS16470 f5a3c93ad7b10c04af7734aec9f9ecf9 862 SUPERFAMILY SSF47323 664 862 1.31E-38 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS16470 f5a3c93ad7b10c04af7734aec9f9ecf9 862 Gene3D G3DSA:3.90.740.10 229 403 1.1E-50 T 28-03-2018 MKLM6_RS16470 f5a3c93ad7b10c04af7734aec9f9ecf9 862 SUPERFAMILY SSF50677 226 415 8.48E-54 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MKLM6_RS09590 2dc035be4e8fecb47d5d7b9a2c369b7b 189 SUPERFAMILY SSF50129 29 68 3.87E-7 T 28-03-2018 IPR011032 GroES-like MKLM6_RS09590 2dc035be4e8fecb47d5d7b9a2c369b7b 189 Gene3D G3DSA:3.90.180.10 5 171 0.001 T 28-03-2018 MKLM6_RS13425 fcc2192c127b8a70516a1beaa1263ec1 285 PIRSF PIRSF004976 1 267 2.8E-71 T 28-03-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 MKLM6_RS13425 fcc2192c127b8a70516a1beaa1263ec1 285 Hamap MF_01850 tRNA 2-thiocytidine biosynthesis protein TtcA [ttcA]. 7 268 56.717 T 28-03-2018 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 MKLM6_RS13425 fcc2192c127b8a70516a1beaa1263ec1 285 Gene3D G3DSA:3.40.50.620 5 231 3.0E-39 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS13425 fcc2192c127b8a70516a1beaa1263ec1 285 SUPERFAMILY SSF52402 14 233 9.43E-55 T 28-03-2018 MKLM6_RS13425 fcc2192c127b8a70516a1beaa1263ec1 285 Pfam PF01171 PP-loop family 38 201 8.4E-15 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 MKLM6_RS21250 9794630045cc0318cf73c8c29f55fc5d 618 Pfam PF10102 Domain of unknown function (DUF2341) 71 154 2.5E-11 T 28-03-2018 IPR018765 Domain of unknown function DUF2341 MKLM6_RS21250 9794630045cc0318cf73c8c29f55fc5d 618 SUPERFAMILY SSF49899 136 346 1.7E-20 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain MKLM6_RS21250 9794630045cc0318cf73c8c29f55fc5d 618 Pfam PF01618 MotA/TolQ/ExbB proton channel family 475 591 7.3E-28 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 MKLM6_RS21250 9794630045cc0318cf73c8c29f55fc5d 618 Gene3D G3DSA:2.60.120.200 138 355 2.2E-23 T 28-03-2018 MKLM6_RS21250 9794630045cc0318cf73c8c29f55fc5d 618 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 194 339 3.8E-10 T 28-03-2018 MKLM6_RS08975 87524da49f7e0e2884f419d63dcc1458 151 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 17 145 7.5E-48 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 MKLM6_RS08975 87524da49f7e0e2884f419d63dcc1458 151 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 147 30.971 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 MKLM6_RS01480 04d7bb977fee2bb3f84b0d02f7bc8110 456 SUPERFAMILY SSF63411 22 234 4.19E-64 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MKLM6_RS01480 04d7bb977fee2bb3f84b0d02f7bc8110 456 SUPERFAMILY SSF63411 246 439 1.67E-34 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MKLM6_RS01480 04d7bb977fee2bb3f84b0d02f7bc8110 456 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 55 78 - T 28-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 MKLM6_RS01480 04d7bb977fee2bb3f84b0d02f7bc8110 456 Pfam PF00675 Insulinase (Peptidase family M16) 36 180 8.6E-29 T 28-03-2018 IPR011765 Peptidase M16, N-terminal MKLM6_RS01480 04d7bb977fee2bb3f84b0d02f7bc8110 456 Gene3D G3DSA:3.30.830.10 249 450 1.1E-35 T 28-03-2018 MKLM6_RS01480 04d7bb977fee2bb3f84b0d02f7bc8110 456 Pfam PF05193 Peptidase M16 inactive domain 191 370 7.3E-25 T 28-03-2018 IPR007863 Peptidase M16, C-terminal MKLM6_RS01480 04d7bb977fee2bb3f84b0d02f7bc8110 456 Gene3D G3DSA:3.30.830.10 18 242 4.1E-68 T 28-03-2018 MKLM6_RS05800 f4d02d8deb270af2326572522ee3ce5f 199 Pfam PF06035 Bacterial transglutaminase-like cysteine proteinase BTLCP 45 150 1.3E-18 T 28-03-2018 IPR010319 Transglutaminase-like cysteine peptidase, predicted MKLM6_RS05800 f4d02d8deb270af2326572522ee3ce5f 199 SUPERFAMILY SSF54001 28 103 8.17E-7 T 28-03-2018 MKLM6_RS13055 7a55be3b4e5e083f953772ac73263a35 284 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 250 276 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS13055 7a55be3b4e5e083f953772ac73263a35 284 SUPERFAMILY SSF88659 197 279 5.61E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS13055 7a55be3b4e5e083f953772ac73263a35 284 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 1 282 49.645 T 28-03-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 MKLM6_RS13055 7a55be3b4e5e083f953772ac73263a35 284 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 15 281 4.2E-120 T 28-03-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 MKLM6_RS13055 7a55be3b4e5e083f953772ac73263a35 284 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 48 278 1.4E-28 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS13055 7a55be3b4e5e083f953772ac73263a35 284 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 77 90 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS13055 7a55be3b4e5e083f953772ac73263a35 284 Pfam PF04545 Sigma-70, region 4 227 278 8.6E-16 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS13055 7a55be3b4e5e083f953772ac73263a35 284 PRINTS PR00046 Major sigma-70 factor signature 77 90 5.3E-17 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS13055 7a55be3b4e5e083f953772ac73263a35 284 PRINTS PR00046 Major sigma-70 factor signature 250 265 5.3E-17 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS13055 7a55be3b4e5e083f953772ac73263a35 284 PRINTS PR00046 Major sigma-70 factor signature 265 276 5.3E-17 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS13055 7a55be3b4e5e083f953772ac73263a35 284 PRINTS PR00046 Major sigma-70 factor signature 231 243 5.3E-17 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS13055 7a55be3b4e5e083f953772ac73263a35 284 Pfam PF04542 Sigma-70 region 2 53 122 1.6E-15 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS13055 7a55be3b4e5e083f953772ac73263a35 284 SUPERFAMILY SSF88946 14 122 1.19E-38 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS13055 7a55be3b4e5e083f953772ac73263a35 284 Gene3D G3DSA:1.10.10.10 222 283 4.0E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS13055 7a55be3b4e5e083f953772ac73263a35 284 Gene3D G3DSA:1.10.601.10 13 122 1.9E-34 T 28-03-2018 MKLM6_RS22440 bd7d8119aaa126a755e13d057f2b30e6 191 Gene3D G3DSA:2.60.40.680 33 171 1.5E-19 T 28-03-2018 MKLM6_RS22440 bd7d8119aaa126a755e13d057f2b30e6 191 Pfam PF00963 Cohesin domain 42 127 6.2E-5 T 28-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 MKLM6_RS22440 bd7d8119aaa126a755e13d057f2b30e6 191 SUPERFAMILY SSF49384 41 156 6.88E-15 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 MKLM6_RS02250 36425d858290679d74d2750fc98b93ef 192 PIRSF PIRSF006305 1 192 1.3E-50 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 MKLM6_RS02250 36425d858290679d74d2750fc98b93ef 192 Gene3D G3DSA:3.90.950.10 1 190 5.2E-66 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MKLM6_RS02250 36425d858290679d74d2750fc98b93ef 192 SUPERFAMILY SSF52972 2 184 3.01E-59 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MKLM6_RS02250 36425d858290679d74d2750fc98b93ef 192 Pfam PF02545 Maf-like protein 4 185 1.4E-54 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 MKLM6_RS02250 36425d858290679d74d2750fc98b93ef 192 Hamap MF_00528 Septum formation protein Maf [maf]. 4 190 32.057 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 MKLM6_RS02250 36425d858290679d74d2750fc98b93ef 192 TIGRFAM TIGR00172 maf: septum formation protein Maf 1 183 2.2E-49 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 MKLM6_RS18760 5fac957eff7acb5f05d26003c8b39ecc 101 Pfam PF04316 Anti-sigma-28 factor, FlgM 38 92 9.5E-18 T 28-03-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal MKLM6_RS18760 5fac957eff7acb5f05d26003c8b39ecc 101 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 1 94 3.8E-22 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 MKLM6_RS18760 5fac957eff7acb5f05d26003c8b39ecc 101 SUPERFAMILY SSF101498 14 93 3.92E-15 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 MKLM6_RS18760 5fac957eff7acb5f05d26003c8b39ecc 101 Gene3D G3DSA:1.10.287.1160 63 92 1.9E-13 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 MKLM6_RS19765 6a1b6ac96412f72a9d97cfb95a900518 534 Gene3D G3DSA:1.25.40.80 156 342 1.2E-43 T 28-03-2018 MKLM6_RS19765 6a1b6ac96412f72a9d97cfb95a900518 534 Pfam PF04244 Deoxyribodipyrimidine photo-lyase-related protein 30 249 4.3E-69 T 28-03-2018 IPR007357 Deoxyribodipyrimidine photolyase-related protein MKLM6_RS19765 6a1b6ac96412f72a9d97cfb95a900518 534 SUPERFAMILY SSF48173 254 520 3.27E-61 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 MKLM6_RS19765 6a1b6ac96412f72a9d97cfb95a900518 534 Gene3D G3DSA:1.10.579.10 343 512 1.6E-30 T 28-03-2018 MKLM6_RS04075 1897577fa6dab9a176f30f4da17aea6c 514 Gene3D G3DSA:3.40.50.150 235 495 2.0E-18 T 28-03-2018 MKLM6_RS04075 1897577fa6dab9a176f30f4da17aea6c 514 SUPERFAMILY SSF53335 238 450 2.31E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS05130 a048e6eef4eccde0a29b24f59b1f399c 206 Gene3D G3DSA:2.60.120.590 3 201 6.2E-52 T 28-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like MKLM6_RS05130 a048e6eef4eccde0a29b24f59b1f399c 206 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 15 192 4.1E-33 T 28-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like MKLM6_RS05130 a048e6eef4eccde0a29b24f59b1f399c 206 SUPERFAMILY SSF51197 12 196 4.53E-62 T 28-03-2018 MKLM6_RS00405 04b736e92024eee1513c074c7e254f8f 95 Pfam PF13737 Transposase DDE domain 22 68 2.2E-9 T 28-03-2018 IPR025668 Transposase DDE domain MKLM6_RS01530 c7a9fdf0d8887841ef5a4ec64093552e 95 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 6 85 3.8E-6 T 28-03-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system MKLM6_RS18190 b6d2834333a131ede5cd1988779ca6ac 447 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 142 441 1.1E-32 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 MKLM6_RS18190 b6d2834333a131ede5cd1988779ca6ac 447 Pfam PF04261 Dyp-type peroxidase family 226 438 3.0E-6 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 MKLM6_RS18190 b6d2834333a131ede5cd1988779ca6ac 447 SUPERFAMILY SSF54909 4 445 4.02E-105 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel MKLM6_RS22425 b26430dd86698b064aae006e6a7b322e 304 SMART SM00450 78 173 5.9E-9 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS22425 b26430dd86698b064aae006e6a7b322e 304 SUPERFAMILY SSF52821 74 174 6.02E-15 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS22425 b26430dd86698b064aae006e6a7b322e 304 Gene3D G3DSA:3.40.250.10 68 197 1.0E-13 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS22425 b26430dd86698b064aae006e6a7b322e 304 Pfam PF00581 Rhodanese-like domain 79 168 5.0E-6 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS07375 f0257d4b7c25fbe9cbe09b97da34d6c3 165 Gene3D G3DSA:1.10.10.10 73 106 5.6E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS07375 f0257d4b7c25fbe9cbe09b97da34d6c3 165 Gene3D G3DSA:1.10.10.10 14 72 3.4E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS07375 f0257d4b7c25fbe9cbe09b97da34d6c3 165 Pfam PF02631 RecX family 40 156 1.7E-29 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 MKLM6_RS07375 f0257d4b7c25fbe9cbe09b97da34d6c3 165 Gene3D G3DSA:1.10.10.10 109 158 4.0E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS07375 f0257d4b7c25fbe9cbe09b97da34d6c3 165 Hamap MF_01114 Regulatory protein RecX [recX]. 15 161 14.143 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 MKLM6_RS17800 e32e1dbc2118407ca637795282ffdaa7 118 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 2 106 2.4E-37 T 28-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 MKLM6_RS17800 e32e1dbc2118407ca637795282ffdaa7 118 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 102 7.6E-22 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MKLM6_RS17800 e32e1dbc2118407ca637795282ffdaa7 118 Gene3D G3DSA:2.60.300.12 1 110 1.2E-35 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MKLM6_RS17800 e32e1dbc2118407ca637795282ffdaa7 118 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 28-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 MKLM6_RS17800 e32e1dbc2118407ca637795282ffdaa7 118 SUPERFAMILY SSF89360 1 95 1.1E-28 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MKLM6_RS15395 e77779695548c7c9a437aadefce8b52e 518 TIGRFAM TIGR03007 pepcterm_ChnLen: polysaccharide chain length determinant protein, PEP-CTERM locus subfamily 7 514 5.6E-120 T 28-03-2018 IPR014345 PEP-CTERM locus polysaccharide chain length determinant MKLM6_RS15395 e77779695548c7c9a437aadefce8b52e 518 Gene3D G3DSA:3.30.1890.10 34 431 1.9E-15 T 28-03-2018 MKLM6_RS18940 49cf1621daca5b6a5f1579a59007af1d 331 SUPERFAMILY SSF52980 98 321 2.57E-27 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MKLM6_RS18940 49cf1621daca5b6a5f1579a59007af1d 331 Gene3D G3DSA:3.40.1350.10 188 329 5.1E-12 T 28-03-2018 MKLM6_RS20155 8a9abdf8a618fb2c88fc382d6880ff16 243 SUPERFAMILY SSF116726 140 225 8.24E-11 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MKLM6_RS20155 8a9abdf8a618fb2c88fc382d6880ff16 243 SUPERFAMILY SSF51735 3 142 3.15E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS20155 8a9abdf8a618fb2c88fc382d6880ff16 243 Gene3D G3DSA:3.40.50.720 1 119 5.6E-16 T 28-03-2018 MKLM6_RS20155 8a9abdf8a618fb2c88fc382d6880ff16 243 Gene3D G3DSA:3.30.70.1450 135 233 1.3E-10 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MKLM6_RS20155 8a9abdf8a618fb2c88fc382d6880ff16 243 Pfam PF02254 TrkA-N domain 4 120 1.7E-20 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MKLM6_RS18670 6979933d3680cd52157faa570b81cd61 317 Pfam PF16344 Domain of unknown function (DUF4974) 232 312 2.7E-14 T 28-03-2018 IPR032508 Protein FecR, C-terminal MKLM6_RS18670 6979933d3680cd52157faa570b81cd61 317 Pfam PF04773 FecR protein 110 202 1.1E-22 T 28-03-2018 IPR006860 FecR protein MKLM6_RS18670 6979933d3680cd52157faa570b81cd61 317 Pfam PF16220 Domain of unknown function (DUF4880) 13 53 1.7E-15 T 28-03-2018 IPR032623 FecR, N-terminal MKLM6_RS18670 6979933d3680cd52157faa570b81cd61 317 PIRSF PIRSF018266 1 317 9.2E-90 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component MKLM6_RS07450 a4f2bcccccad33d1b87326020151c6fd 108 SUPERFAMILY SSF46955 50 103 7.14E-7 T 28-03-2018 IPR009061 Putative DNA-binding domain MKLM6_RS07450 a4f2bcccccad33d1b87326020151c6fd 108 Pfam PF12728 Helix-turn-helix domain 50 102 5.9E-9 T 28-03-2018 MKLM6_RS07450 a4f2bcccccad33d1b87326020151c6fd 108 Gene3D G3DSA:1.10.10.10 50 107 6.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS00455 40b4b7ecc4bfe9fe67bfcb6cd402327c 301 SUPERFAMILY SSF56281 1 293 5.46E-49 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS00455 40b4b7ecc4bfe9fe67bfcb6cd402327c 301 Gene3D G3DSA:3.60.15.10 1 299 7.0E-43 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS00455 40b4b7ecc4bfe9fe67bfcb6cd402327c 301 SMART SM00849 25 208 1.6E-10 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS00455 40b4b7ecc4bfe9fe67bfcb6cd402327c 301 Pfam PF12706 Beta-lactamase superfamily domain 39 256 3.7E-22 T 28-03-2018 IPR001279 Metallo-beta-lactamase MKLM6_RS03880 cd497d0f13253b2ca03542ef85ba44bd 138 Pfam PF03061 Thioesterase superfamily 25 110 3.6E-20 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MKLM6_RS03880 cd497d0f13253b2ca03542ef85ba44bd 138 SUPERFAMILY SSF54637 9 137 2.49E-43 T 28-03-2018 IPR029069 HotDog domain MKLM6_RS03880 cd497d0f13253b2ca03542ef85ba44bd 138 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 14 129 4.0E-38 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 MKLM6_RS03880 cd497d0f13253b2ca03542ef85ba44bd 138 PIRSF PIRSF003230 3 138 1.0E-46 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 MKLM6_RS03880 cd497d0f13253b2ca03542ef85ba44bd 138 Gene3D G3DSA:3.10.129.10 4 138 5.5E-41 T 28-03-2018 MKLM6_RS03880 cd497d0f13253b2ca03542ef85ba44bd 138 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 11 134 3.3E-53 T 28-03-2018 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 MKLM6_RS02175 c648e7151dd910a0a04ce9afba1f1981 183 Pfam PF00293 NUDIX domain 45 149 2.1E-13 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MKLM6_RS02175 c648e7151dd910a0a04ce9afba1f1981 183 ProSitePatterns PS00893 Nudix box signature. 79 100 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MKLM6_RS02175 c648e7151dd910a0a04ce9afba1f1981 183 SUPERFAMILY SSF55811 5 179 5.28E-34 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MKLM6_RS02175 c648e7151dd910a0a04ce9afba1f1981 183 Gene3D G3DSA:3.90.79.10 5 183 1.0E-29 T 28-03-2018 MKLM6_RS22270 48416b88a3d058fd6a0e78a48ac8ee50 71 Pfam PF12728 Helix-turn-helix domain 8 56 5.0E-14 T 28-03-2018 MKLM6_RS22270 48416b88a3d058fd6a0e78a48ac8ee50 71 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 8 55 1.4E-17 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 MKLM6_RS22270 48416b88a3d058fd6a0e78a48ac8ee50 71 SUPERFAMILY SSF46955 7 55 3.11E-9 T 28-03-2018 IPR009061 Putative DNA-binding domain MKLM6_RS22270 48416b88a3d058fd6a0e78a48ac8ee50 71 Gene3D G3DSA:1.10.1660.20 6 50 3.1E-13 T 28-03-2018 MKLM6_RS21965 6a1283a784f13b030db76f654b7d09f5 271 Gene3D G3DSA:3.60.40.10 7 270 9.3E-37 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS21965 6a1283a784f13b030db76f654b7d09f5 271 Pfam PF13672 Protein phosphatase 2C 22 236 9.1E-13 T 28-03-2018 MKLM6_RS21965 6a1283a784f13b030db76f654b7d09f5 271 SMART SM00332 2 269 2.4E-12 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS21965 6a1283a784f13b030db76f654b7d09f5 271 SMART SM00331 16 271 2.5E-23 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS21965 6a1283a784f13b030db76f654b7d09f5 271 SUPERFAMILY SSF81606 12 72 2.22E-50 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS21965 6a1283a784f13b030db76f654b7d09f5 271 SUPERFAMILY SSF81606 99 270 2.22E-50 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MKLM6_RS03320 bb5ac8fae38b82ef09e30c6da972f4fd 227 Gene3D G3DSA:2.60.120.620 1 188 2.3E-31 T 28-03-2018 MKLM6_RS03320 bb5ac8fae38b82ef09e30c6da972f4fd 227 Hamap MF_00657 PKHD-type hydroxylase YbiX [ybiX]. 1 227 45.814 T 28-03-2018 IPR023550 PKHD-type hydroxylase GO:0016706|GO:0055114 MKLM6_RS03320 bb5ac8fae38b82ef09e30c6da972f4fd 227 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 84 177 6.8E-13 T 28-03-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 MKLM6_RS03320 bb5ac8fae38b82ef09e30c6da972f4fd 227 SMART SM00702 1 178 1.7E-16 T 28-03-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 MKLM6_RS16550 0d6cad4d58805c129fcd7e210934d4bc 145 Pfam PF00581 Rhodanese-like domain 30 129 1.9E-14 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS16550 0d6cad4d58805c129fcd7e210934d4bc 145 SMART SM00450 26 134 2.1E-12 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS16550 0d6cad4d58805c129fcd7e210934d4bc 145 Gene3D G3DSA:3.40.250.10 12 140 6.8E-22 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS16550 0d6cad4d58805c129fcd7e210934d4bc 145 SUPERFAMILY SSF52821 25 138 1.3E-22 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS09455 0bb3186a0d87e6798ee613127c3dbd7b 247 TIGRFAM TIGR03864 PQQ_ABC_ATP: ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system 4 239 1.3E-108 T 28-03-2018 IPR022467 ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system MKLM6_RS09455 0bb3186a0d87e6798ee613127c3dbd7b 247 SMART SM00382 29 211 6.4E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS09455 0bb3186a0d87e6798ee613127c3dbd7b 247 SUPERFAMILY SSF52540 4 227 1.66E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS09455 0bb3186a0d87e6798ee613127c3dbd7b 247 Gene3D G3DSA:3.40.50.300 1 244 1.7E-62 T 28-03-2018 MKLM6_RS09455 0bb3186a0d87e6798ee613127c3dbd7b 247 Pfam PF00005 ABC transporter 20 163 1.9E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS14485 9996d24e7071455d447db7fe36415c42 398 SUPERFAMILY SSF56796 6 396 2.49E-89 T 28-03-2018 MKLM6_RS14485 9996d24e7071455d447db7fe36415c42 398 Gene3D G3DSA:1.20.1090.10 192 398 1.6E-39 T 28-03-2018 MKLM6_RS14485 9996d24e7071455d447db7fe36415c42 398 Pfam PF00465 Iron-containing alcohol dehydrogenase 14 390 2.8E-95 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 MKLM6_RS14485 9996d24e7071455d447db7fe36415c42 398 Gene3D G3DSA:3.40.50.1970 13 190 2.2E-40 T 28-03-2018 MKLM6_RS13985 73796cb28646038e222d8b23cc40f422 69 Pfam PF06945 Protein of unknown function (DUF1289) 4 29 1.7E-8 T 28-03-2018 IPR010710 Protein of unknown function DUF1289 MKLM6_RS12890 928fdb524186ff8c6328db6c4fbf7074 262 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 137 149 - T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 MKLM6_RS12890 928fdb524186ff8c6328db6c4fbf7074 262 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 10 251 1.3E-69 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 MKLM6_RS12890 928fdb524186ff8c6328db6c4fbf7074 262 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 8 257 4.5E-52 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 MKLM6_RS12890 928fdb524186ff8c6328db6c4fbf7074 262 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 7 256 16.186 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 MKLM6_RS21535 93db40f24a82969321f8033b5b89d1d0 435 Pfam PF02321 Outer membrane efflux protein 62 238 4.0E-10 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS21535 93db40f24a82969321f8033b5b89d1d0 435 Pfam PF02321 Outer membrane efflux protein 293 425 7.8E-13 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS21535 93db40f24a82969321f8033b5b89d1d0 435 Gene3D G3DSA:1.20.1600.10 52 434 9.0E-33 T 28-03-2018 MKLM6_RS21535 93db40f24a82969321f8033b5b89d1d0 435 SUPERFAMILY SSF56954 10 433 9.94E-34 T 28-03-2018 MKLM6_RS04195 272d66f3d40d9c8caf1339078d57b837 118 Pfam PF13693 Winged helix-turn-helix DNA-binding 19 89 1.1E-25 T 28-03-2018 MKLM6_RS04195 272d66f3d40d9c8caf1339078d57b837 118 Gene3D G3DSA:1.10.260.40 12 86 4.0E-11 T 28-03-2018 MKLM6_RS04195 272d66f3d40d9c8caf1339078d57b837 118 SUPERFAMILY SSF47413 16 84 9.0E-20 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MKLM6_RS13430 a6d501a8ee9c993cc3f545c61793836a 348 Gene3D G3DSA:3.90.25.10 189 348 3.2E-39 T 28-03-2018 MKLM6_RS13430 a6d501a8ee9c993cc3f545c61793836a 348 SUPERFAMILY SSF51735 1 347 5.2E-99 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS13430 a6d501a8ee9c993cc3f545c61793836a 348 Gene3D G3DSA:3.40.50.720 2 188 9.7E-37 T 28-03-2018 MKLM6_RS13430 a6d501a8ee9c993cc3f545c61793836a 348 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 336 2.0E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS13430 a6d501a8ee9c993cc3f545c61793836a 348 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 5 346 4.9E-135 T 28-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 MKLM6_RS01170 e0baa07b1b79ee494bdefc998599851b 319 Pfam PF00691 OmpA family 170 266 5.8E-12 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS01170 e0baa07b1b79ee494bdefc998599851b 319 SUPERFAMILY SSF103088 166 274 1.44E-18 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS01170 e0baa07b1b79ee494bdefc998599851b 319 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 10 64 6.8E-21 T 28-03-2018 IPR025713 Motility protein B, N-terminal domain MKLM6_RS01170 e0baa07b1b79ee494bdefc998599851b 319 Gene3D G3DSA:3.30.1330.60 117 299 8.2E-36 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS14435 f644ccf8a9139ccef797dd090ac65c4b 478 Pfam PF02321 Outer membrane efflux protein 66 265 3.9E-17 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS14435 f644ccf8a9139ccef797dd090ac65c4b 478 Pfam PF02321 Outer membrane efflux protein 295 474 1.1E-18 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS14435 f644ccf8a9139ccef797dd090ac65c4b 478 Gene3D G3DSA:1.20.1600.10 24 478 4.3E-74 T 28-03-2018 MKLM6_RS14435 f644ccf8a9139ccef797dd090ac65c4b 478 SUPERFAMILY SSF56954 6 477 1.57E-86 T 28-03-2018 MKLM6_RS14435 f644ccf8a9139ccef797dd090ac65c4b 478 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 14 476 4.4E-73 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 MKLM6_RS02695 28c26efb8ec83bea9001d15e5b242f2e 329 ProSitePatterns PS01054 Transaldolase signature 1. 32 40 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 MKLM6_RS02695 28c26efb8ec83bea9001d15e5b242f2e 329 SUPERFAMILY SSF51569 3 323 1.15E-107 T 28-03-2018 MKLM6_RS02695 28c26efb8ec83bea9001d15e5b242f2e 329 TIGRFAM TIGR00874 talAB: transaldolase 4 324 2.4E-138 T 28-03-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 MKLM6_RS02695 28c26efb8ec83bea9001d15e5b242f2e 329 Hamap MF_00492 Transaldolase [tal]. 3 324 47.674 T 28-03-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 MKLM6_RS02695 28c26efb8ec83bea9001d15e5b242f2e 329 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 15 319 4.2E-93 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 MKLM6_RS02695 28c26efb8ec83bea9001d15e5b242f2e 329 Gene3D G3DSA:3.20.20.70 3 324 3.9E-112 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS20455 eb6e039ff5084f80ebb9016ef679dcab 406 SUPERFAMILY SSF51261 222 400 7.85E-46 T 28-03-2018 IPR011055 Duplicated hybrid motif MKLM6_RS20455 eb6e039ff5084f80ebb9016ef679dcab 406 Pfam PF01551 Peptidase family M23 303 396 4.7E-24 T 28-03-2018 IPR016047 Peptidase M23 MKLM6_RS20455 eb6e039ff5084f80ebb9016ef679dcab 406 Gene3D G3DSA:2.70.70.10 157 405 3.6E-34 T 28-03-2018 MKLM6_RS20455 eb6e039ff5084f80ebb9016ef679dcab 406 Gene3D G3DSA:1.20.5.340 19 122 4.9E-7 T 28-03-2018 MKLM6_RS11435 222433c0505688803755533c86ee1e32 201 SUPERFAMILY SSF55729 17 145 2.84E-14 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS11435 222433c0505688803755533c86ee1e32 201 Gene3D G3DSA:3.40.630.30 2 163 1.8E-13 T 28-03-2018 MKLM6_RS11435 222433c0505688803755533c86ee1e32 201 Pfam PF00583 Acetyltransferase (GNAT) family 38 147 1.8E-4 T 28-03-2018 IPR000182 GNAT domain GO:0008080 MKLM6_RS12625 7aa396d2e99edb2957be06b6680dca68 396 Gene3D G3DSA:3.40.640.10 9 261 1.5E-65 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MKLM6_RS12625 7aa396d2e99edb2957be06b6680dca68 396 PIRSF PIRSF001434 2 396 2.4E-134 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MKLM6_RS12625 7aa396d2e99edb2957be06b6680dca68 396 Hamap MF_02056 O-succinylhomoserine sulfhydrylase [metZ]. 13 394 53.258 T 28-03-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 MKLM6_RS12625 7aa396d2e99edb2957be06b6680dca68 396 SUPERFAMILY SSF53383 23 394 8.55E-126 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MKLM6_RS12625 7aa396d2e99edb2957be06b6680dca68 396 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 12 393 1.2E-143 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MKLM6_RS12625 7aa396d2e99edb2957be06b6680dca68 396 TIGRFAM TIGR01325 O_suc_HS_sulf: O-succinylhomoserine sulfhydrylase 12 393 5.4E-171 T 28-03-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 MKLM6_RS12625 7aa396d2e99edb2957be06b6680dca68 396 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 203 217 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MKLM6_RS12625 7aa396d2e99edb2957be06b6680dca68 396 Gene3D G3DSA:3.90.1150.10 263 396 5.7E-50 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MKLM6_RS21255 adf18b12f4f02bb653d74e0c671036f3 353 Gene3D G3DSA:3.90.420.10 4 172 1.4E-9 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 MKLM6_RS21255 adf18b12f4f02bb653d74e0c671036f3 353 SUPERFAMILY SSF56524 51 143 5.62E-5 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 MKLM6_RS21255 adf18b12f4f02bb653d74e0c671036f3 353 SUPERFAMILY SSF56524 167 320 3.79E-10 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 MKLM6_RS21255 adf18b12f4f02bb653d74e0c671036f3 353 Gene3D G3DSA:3.90.420.10 173 325 1.7E-13 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 MKLM6_RS20065 460ef0d6e3273617f53ab33fa30afd89 96 Gene3D G3DSA:3.40.30.10 1 95 2.5E-41 T 28-03-2018 MKLM6_RS20065 460ef0d6e3273617f53ab33fa30afd89 96 TIGRFAM TIGR02174 CXXU_selWTH: selT/selW/selH selenoprotein domain 5 76 5.7E-23 T 28-03-2018 IPR011893 Selenoprotein, Rdx type MKLM6_RS20065 460ef0d6e3273617f53ab33fa30afd89 96 Pfam PF10262 Rdx family 4 77 1.0E-32 T 28-03-2018 IPR011893 Selenoprotein, Rdx type MKLM6_RS20065 460ef0d6e3273617f53ab33fa30afd89 96 SUPERFAMILY SSF52833 2 86 7.6E-29 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS15365 c84f7fd4f5ef9c7e68b47a1e8b0215af 339 Gene3D G3DSA:3.40.630.30 147 287 4.2E-25 T 28-03-2018 MKLM6_RS15365 c84f7fd4f5ef9c7e68b47a1e8b0215af 339 SUPERFAMILY SSF55729 2 113 8.05E-8 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS15365 c84f7fd4f5ef9c7e68b47a1e8b0215af 339 TIGRFAM TIGR03019 pepcterm_femAB: FemAB-related protein, PEP-CTERM system-associated 12 339 1.5E-149 T 28-03-2018 IPR017469 PEP-CTERM system-associated, FemAB-related MKLM6_RS15365 c84f7fd4f5ef9c7e68b47a1e8b0215af 339 Gene3D G3DSA:3.40.630.30 1 146 7.6E-25 T 28-03-2018 MKLM6_RS15365 c84f7fd4f5ef9c7e68b47a1e8b0215af 339 SUPERFAMILY SSF55729 138 297 1.5E-34 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS15365 c84f7fd4f5ef9c7e68b47a1e8b0215af 339 Pfam PF13480 Acetyltransferase (GNAT) domain 148 280 1.5E-13 T 28-03-2018 MKLM6_RS01970 147122a03cee387e5f5c1ccb580837d7 157 PIRSF PIRSF016487 1 157 1.8E-57 T 28-03-2018 IPR012042 Inorganic triphosphatase NeuTTM/CthTTM-like MKLM6_RS01970 147122a03cee387e5f5c1ccb580837d7 157 SUPERFAMILY SSF55154 1 150 2.94E-37 T 28-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 MKLM6_RS01970 147122a03cee387e5f5c1ccb580837d7 157 Gene3D G3DSA:2.40.320.10 1 153 5.2E-33 T 28-03-2018 MKLM6_RS01970 147122a03cee387e5f5c1ccb580837d7 157 SMART SM01118 2 149 9.8E-13 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 MKLM6_RS01970 147122a03cee387e5f5c1ccb580837d7 157 Pfam PF01928 CYTH domain 3 144 1.6E-6 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 MKLM6_RS18595 019af3b2ed00758a11cfbf2c9bc4d7f9 314 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 13 297 5.5E-60 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MKLM6_RS18595 019af3b2ed00758a11cfbf2c9bc4d7f9 314 Gene3D G3DSA:3.30.70.1350 223 308 6.4E-19 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain MKLM6_RS18595 019af3b2ed00758a11cfbf2c9bc4d7f9 314 Gene3D G3DSA:1.20.1510.10 9 222 5.5E-36 T 28-03-2018 MKLM6_RS18595 019af3b2ed00758a11cfbf2c9bc4d7f9 314 Pfam PF01545 Cation efflux family 13 222 1.2E-37 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MKLM6_RS18595 019af3b2ed00758a11cfbf2c9bc4d7f9 314 Pfam PF16916 Dimerisation domain of Zinc Transporter 226 304 3.4E-20 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain MKLM6_RS18595 019af3b2ed00758a11cfbf2c9bc4d7f9 314 SUPERFAMILY SSF161111 12 223 3.79E-44 T 28-03-2018 MKLM6_RS18595 019af3b2ed00758a11cfbf2c9bc4d7f9 314 SUPERFAMILY SSF160240 225 305 1.01E-18 T 28-03-2018 MKLM6_RS19015 507d46ae9ae7d881c7a2f086ec03bb45 434 SUPERFAMILY SSF109604 210 366 6.8E-13 T 28-03-2018 MKLM6_RS19015 507d46ae9ae7d881c7a2f086ec03bb45 434 Gene3D G3DSA:3.40.50.2300 1 190 4.4E-33 T 28-03-2018 MKLM6_RS19015 507d46ae9ae7d881c7a2f086ec03bb45 434 SUPERFAMILY SSF52172 11 175 5.83E-35 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS19015 507d46ae9ae7d881c7a2f086ec03bb45 434 Pfam PF00072 Response regulator receiver domain 13 120 4.1E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS19015 507d46ae9ae7d881c7a2f086ec03bb45 434 SMART SM00448 10 122 5.7E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS19015 507d46ae9ae7d881c7a2f086ec03bb45 434 Pfam PF13487 HD domain 260 317 1.6E-17 T 28-03-2018 MKLM6_RS19015 507d46ae9ae7d881c7a2f086ec03bb45 434 Gene3D G3DSA:1.10.3210.10 205 374 1.3E-22 T 28-03-2018 MKLM6_RS19405 ca42980f5510bed42c4429a8868f7c3d 309 Pfam PF02355 Protein export membrane protein 114 289 5.7E-66 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial MKLM6_RS19405 ca42980f5510bed42c4429a8868f7c3d 309 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 110 279 8.3E-55 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MKLM6_RS19405 ca42980f5510bed42c4429a8868f7c3d 309 Gene3D G3DSA:1.20.1640.10 81 297 5.5E-34 T 28-03-2018 MKLM6_RS19405 ca42980f5510bed42c4429a8868f7c3d 309 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 35 282 1.3E-82 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 MKLM6_RS19405 ca42980f5510bed42c4429a8868f7c3d 309 Pfam PF07549 SecD/SecF GG Motif 29 56 7.5E-10 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site MKLM6_RS19405 ca42980f5510bed42c4429a8868f7c3d 309 PRINTS PR01755 Bacterial translocase SecF protein signature 230 245 1.0E-29 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MKLM6_RS19405 ca42980f5510bed42c4429a8868f7c3d 309 PRINTS PR01755 Bacterial translocase SecF protein signature 149 163 1.0E-29 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MKLM6_RS19405 ca42980f5510bed42c4429a8868f7c3d 309 PRINTS PR01755 Bacterial translocase SecF protein signature 197 215 1.0E-29 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MKLM6_RS19405 ca42980f5510bed42c4429a8868f7c3d 309 PRINTS PR01755 Bacterial translocase SecF protein signature 34 49 1.0E-29 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MKLM6_RS19405 ca42980f5510bed42c4429a8868f7c3d 309 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 7 293 29.139 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 MKLM6_RS19405 ca42980f5510bed42c4429a8868f7c3d 309 SUPERFAMILY SSF82866 71 290 4.71E-41 T 28-03-2018 MKLM6_RS17590 08cc4f1ec2e68ee3936c8b4105d2f4e9 586 SUPERFAMILY SSF110997 508 581 1.44E-6 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 MKLM6_RS17590 08cc4f1ec2e68ee3936c8b4105d2f4e9 586 Gene3D G3DSA:1.20.5.320 386 512 0.0011 T 28-03-2018 MKLM6_RS17590 08cc4f1ec2e68ee3936c8b4105d2f4e9 586 Gene3D G3DSA:1.20.5.320 294 367 0.03 T 28-03-2018 MKLM6_RS17590 08cc4f1ec2e68ee3936c8b4105d2f4e9 586 Pfam PF05036 Sporulation related domain 508 573 1.5E-6 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 MKLM6_RS17590 08cc4f1ec2e68ee3936c8b4105d2f4e9 586 Gene3D G3DSA:3.30.70.1070 513 584 4.9E-7 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 MKLM6_RS16325 235a3337583e418d1c9cb93fb683e942 513 Pfam PF13148 Protein of unknown function (DUF3987) 56 431 2.8E-84 T 28-03-2018 IPR025048 Protein of unknown function DUF3987) MKLM6_RS18255 f20d9a3c50becd4987f3dcbf2842568f 316 Pfam PF01435 Peptidase family M48 75 281 9.5E-29 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MKLM6_RS18255 f20d9a3c50becd4987f3dcbf2842568f 316 Gene3D G3DSA:3.30.2010.10 68 158 3.5E-18 T 28-03-2018 MKLM6_RS13875 3daae87fbd381bdea931a9a7c3c0836e 511 Gene3D G3DSA:3.10.350.10 452 511 3.1E-11 T 28-03-2018 MKLM6_RS13875 3daae87fbd381bdea931a9a7c3c0836e 511 Pfam PF11741 AMIN domain 34 119 1.7E-10 T 28-03-2018 IPR021731 AMIN domain MKLM6_RS13875 3daae87fbd381bdea931a9a7c3c0836e 511 SUPERFAMILY SSF53187 319 395 1.41E-51 T 28-03-2018 MKLM6_RS13875 3daae87fbd381bdea931a9a7c3c0836e 511 SUPERFAMILY SSF53187 177 273 1.41E-51 T 28-03-2018 MKLM6_RS13875 3daae87fbd381bdea931a9a7c3c0836e 511 SUPERFAMILY SSF54106 464 509 8.5E-10 T 28-03-2018 IPR018392 LysM domain MKLM6_RS13875 3daae87fbd381bdea931a9a7c3c0836e 511 SMART SM00257 465 508 2.1E-12 T 28-03-2018 IPR018392 LysM domain MKLM6_RS13875 3daae87fbd381bdea931a9a7c3c0836e 511 Pfam PF01476 LysM domain 466 508 4.6E-11 T 28-03-2018 IPR018392 LysM domain MKLM6_RS13875 3daae87fbd381bdea931a9a7c3c0836e 511 SMART SM00646 239 392 2.7E-48 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MKLM6_RS13875 3daae87fbd381bdea931a9a7c3c0836e 511 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 179 392 7.7E-49 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MKLM6_RS13875 3daae87fbd381bdea931a9a7c3c0836e 511 Gene3D G3DSA:3.40.630.40 174 401 7.5E-53 T 28-03-2018 MKLM6_RS00625 c2e864ced153abe60a7abf5ddd141845 157 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 138 13.268 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MKLM6_RS00625 c2e864ced153abe60a7abf5ddd141845 157 Gene3D G3DSA:1.20.5.620 51 122 2.2E-13 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain MKLM6_RS00625 c2e864ced153abe60a7abf5ddd141845 157 SUPERFAMILY SSF81573 63 121 3.66E-13 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain MKLM6_RS00625 c2e864ced153abe60a7abf5ddd141845 157 Pfam PF00430 ATP synthase B/B' CF(0) 6 136 1.0E-29 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MKLM6_RS00625 c2e864ced153abe60a7abf5ddd141845 157 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 10 155 1.2E-43 T 28-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 MKLM6_RS21125 0831ae0116effeee43f8185f7be2ad01 185 SUPERFAMILY SSF51182 7 182 8.5E-40 T 28-03-2018 IPR011051 RmlC-like cupin domain MKLM6_RS21125 0831ae0116effeee43f8185f7be2ad01 185 Gene3D G3DSA:2.60.120.10 2 156 4.9E-39 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS21125 0831ae0116effeee43f8185f7be2ad01 185 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 171 37.032 T 28-03-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.53+1.13.11.54|MetaCyc: PWY-4361|MetaCyc: PWY-5389 MKLM6_RS21125 0831ae0116effeee43f8185f7be2ad01 185 Pfam PF03079 ARD/ARD' family 27 164 1.6E-38 T 28-03-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 MKLM6_RS20590 4ed00e092465c920955b546c620cfe13 464 PIRSF PIRSF006060 9 464 7.0E-85 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MKLM6_RS20590 4ed00e092465c920955b546c620cfe13 464 Pfam PF13520 Amino acid permease 31 430 1.0E-51 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MKLM6_RS14580 45ebdf775b817aa01b0f10f73f32d56e 230 Pfam PF01844 HNH endonuclease 31 76 2.0E-5 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 MKLM6_RS14580 45ebdf775b817aa01b0f10f73f32d56e 230 Gene3D G3DSA:3.40.1800.10 13 86 1.6E-11 T 28-03-2018 MKLM6_RS01630 8673baff393a1052f813eba321f7076f 354 Pfam PF01594 AI-2E family transporter 12 339 4.4E-49 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like MKLM6_RS15515 3fa2ea530ff12ecc3b84603a6f08489e 88 Gene3D G3DSA:3.30.70.260 4 88 1.4E-29 T 28-03-2018 MKLM6_RS15515 3fa2ea530ff12ecc3b84603a6f08489e 88 SUPERFAMILY SSF117991 4 88 1.24E-25 T 28-03-2018 IPR027471 YbeD-like domain MKLM6_RS15515 3fa2ea530ff12ecc3b84603a6f08489e 88 Pfam PF04359 Protein of unknown function (DUF493) 6 88 9.4E-30 T 28-03-2018 IPR007454 Uncharacterised protein family UPF0250 MKLM6_RS15515 3fa2ea530ff12ecc3b84603a6f08489e 88 Hamap MF_00659 UPF0250 protein YbeD [ybeD]. 2 88 20.97 T 28-03-2018 IPR007454 Uncharacterised protein family UPF0250 MKLM6_RS22480 973fd901e3e7f33bf2993a620f2f4ca9 167 Pfam PF05280 Flagellar transcriptional activator (FlhC) 11 165 3.7E-17 T 28-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 MKLM6_RS22480 973fd901e3e7f33bf2993a620f2f4ca9 167 SUPERFAMILY SSF160930 12 163 1.23E-24 T 28-03-2018 MKLM6_RS10875 86a72adac15b34b6d633ce13b6824a3f 253 Pfam PF01578 Cytochrome C assembly protein 23 191 7.2E-31 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 MKLM6_RS10875 86a72adac15b34b6d633ce13b6824a3f 253 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 52 233 3.6E-81 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10875 86a72adac15b34b6d633ce13b6824a3f 253 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 69 89 2.3E-57 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10875 86a72adac15b34b6d633ce13b6824a3f 253 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 211 235 2.3E-57 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10875 86a72adac15b34b6d633ce13b6824a3f 253 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 128 148 2.3E-57 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10875 86a72adac15b34b6d633ce13b6824a3f 253 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 52 69 2.3E-57 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10875 86a72adac15b34b6d633ce13b6824a3f 253 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 107 127 2.3E-57 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10875 86a72adac15b34b6d633ce13b6824a3f 253 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 163 189 2.3E-57 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS19280 64a5bddb1ab61a05072868e28396fa2a 529 Pfam PF00361 Proton-conducting membrane transporter 125 342 8.9E-52 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS19280 64a5bddb1ab61a05072868e28396fa2a 529 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 215 236 4.5E-32 T 28-03-2018 MKLM6_RS19280 64a5bddb1ab61a05072868e28396fa2a 529 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 149 170 4.5E-32 T 28-03-2018 MKLM6_RS19280 64a5bddb1ab61a05072868e28396fa2a 529 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 237 263 4.5E-32 T 28-03-2018 MKLM6_RS19280 64a5bddb1ab61a05072868e28396fa2a 529 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 74 99 4.5E-32 T 28-03-2018 MKLM6_RS19280 64a5bddb1ab61a05072868e28396fa2a 529 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 102 122 4.5E-32 T 28-03-2018 MKLM6_RS19280 64a5bddb1ab61a05072868e28396fa2a 529 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 304 316 4.5E-32 T 28-03-2018 MKLM6_RS19280 64a5bddb1ab61a05072868e28396fa2a 529 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 66 111 2.7E-9 T 28-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS19065 ee659eae16e0624489a47321e27e9cca 304 SUPERFAMILY SSF53850 88 292 3.8E-43 T 28-03-2018 MKLM6_RS19065 ee659eae16e0624489a47321e27e9cca 304 Gene3D G3DSA:3.40.190.10 176 261 8.1E-28 T 28-03-2018 MKLM6_RS19065 ee659eae16e0624489a47321e27e9cca 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.3E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS19065 ee659eae16e0624489a47321e27e9cca 304 Gene3D G3DSA:1.10.10.10 1 86 4.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS19065 ee659eae16e0624489a47321e27e9cca 304 SUPERFAMILY SSF46785 1 85 7.7E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS19065 ee659eae16e0624489a47321e27e9cca 304 Pfam PF03466 LysR substrate binding domain 87 288 6.2E-49 T 28-03-2018 IPR005119 LysR, substrate-binding MKLM6_RS19065 ee659eae16e0624489a47321e27e9cca 304 Gene3D G3DSA:3.40.190.10 88 175 1.1E-20 T 28-03-2018 MKLM6_RS19065 ee659eae16e0624489a47321e27e9cca 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS19065 ee659eae16e0624489a47321e27e9cca 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS19065 ee659eae16e0624489a47321e27e9cca 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MKLM6_RS13115 0219ec519befbc2f5b5e6450cfc120dc 200 Pfam PF00034 Cytochrome c 95 180 1.7E-9 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS13115 0219ec519befbc2f5b5e6450cfc120dc 200 SUPERFAMILY SSF46626 87 190 3.44E-12 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS13115 0219ec519befbc2f5b5e6450cfc120dc 200 Gene3D G3DSA:1.10.760.10 54 187 1.9E-12 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS06865 b8062d8a48740cab34bbb5686ad4e0b1 200 SUPERFAMILY SSF52972 5 189 3.4E-58 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MKLM6_RS06865 b8062d8a48740cab34bbb5686ad4e0b1 200 TIGRFAM TIGR00172 maf: septum formation protein Maf 5 188 3.0E-47 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 MKLM6_RS06865 b8062d8a48740cab34bbb5686ad4e0b1 200 PIRSF PIRSF006305 1 196 3.8E-50 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 MKLM6_RS06865 b8062d8a48740cab34bbb5686ad4e0b1 200 Gene3D G3DSA:3.90.950.10 5 197 1.1E-56 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MKLM6_RS06865 b8062d8a48740cab34bbb5686ad4e0b1 200 Pfam PF02545 Maf-like protein 6 189 3.3E-44 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 MKLM6_RS06865 b8062d8a48740cab34bbb5686ad4e0b1 200 Hamap MF_00528 Septum formation protein Maf [maf]. 6 194 29.6 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 MKLM6_RS08110 015e64e5cff4f78db5f662dd5c34a55e 160 Pfam PF13230 Glutamine amidotransferases class-II 1 62 2.9E-5 T 28-03-2018 IPR026869 Putative glutamine amidotransferase type 2 MKLM6_RS08110 015e64e5cff4f78db5f662dd5c34a55e 160 Gene3D G3DSA:3.60.20.10 1 101 1.7E-5 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MKLM6_RS08110 015e64e5cff4f78db5f662dd5c34a55e 160 SUPERFAMILY SSF56235 2 88 3.22E-7 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MKLM6_RS19440 a320e949f28d67a527761979f4233610 106 SUPERFAMILY SSF103481 5 103 5.62E-20 T 28-03-2018 MKLM6_RS19440 a320e949f28d67a527761979f4233610 106 Pfam PF00893 Small Multidrug Resistance protein 1 93 8.4E-29 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 MKLM6_RS00380 8870f61dfd8f9a35d7f2c8f7df5f7188 721 Pfam PF06414 Zeta toxin 393 579 1.6E-13 T 28-03-2018 IPR010488 Zeta toxin domain GO:0005524|GO:0016301 MKLM6_RS06525 d934ac5f54783d211e1e034511de573f 335 Pfam PF00795 Carbon-nitrogen hydrolase 8 280 1.2E-55 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS06525 d934ac5f54783d211e1e034511de573f 335 ProSitePatterns PS00921 Nitrilases / cyanide hydratase active site signature. 159 172 - T 28-03-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 MKLM6_RS06525 d934ac5f54783d211e1e034511de573f 335 TIGRFAM TIGR04048 nitrile_sll0784: putative nitrilase, sll0784 family 6 304 8.4E-171 T 28-03-2018 IPR023919 Nitrilase-related, sll0784 MKLM6_RS06525 d934ac5f54783d211e1e034511de573f 335 Gene3D G3DSA:3.60.110.10 1 311 1.9E-62 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS06525 d934ac5f54783d211e1e034511de573f 335 SUPERFAMILY SSF56317 5 298 2.75E-76 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS08455 f967b856a388ac5a1af94b3859a8d845 263 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS08455 f967b856a388ac5a1af94b3859a8d845 263 Gene3D G3DSA:3.40.50.300 2 260 1.2E-53 T 28-03-2018 MKLM6_RS08455 f967b856a388ac5a1af94b3859a8d845 263 Pfam PF00005 ABC transporter 23 170 3.1E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS08455 f967b856a388ac5a1af94b3859a8d845 263 SMART SM00382 30 219 1.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS08455 f967b856a388ac5a1af94b3859a8d845 263 SUPERFAMILY SSF52540 5 241 3.11E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS09780 c5f2dc7b2010e2e2f9c4e04853107dcf 433 Gene3D G3DSA:1.10.150.130 53 218 2.1E-15 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal MKLM6_RS09780 c5f2dc7b2010e2e2f9c4e04853107dcf 433 Pfam PF00589 Phage integrase family 220 400 2.6E-22 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS09780 c5f2dc7b2010e2e2f9c4e04853107dcf 433 SUPERFAMILY SSF56349 133 406 1.91E-47 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS09780 c5f2dc7b2010e2e2f9c4e04853107dcf 433 Gene3D G3DSA:1.10.443.10 219 402 3.9E-30 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS09780 c5f2dc7b2010e2e2f9c4e04853107dcf 433 Pfam PF13356 Arm DNA-binding domain 6 89 6.7E-12 T 28-03-2018 IPR025166 Integrase, DNA-binding domain MKLM6_RS19770 3f55b9f263e528450088b682fb221640 49 Pfam PF10013 Uncharacterized protein conserved in bacteria (DUF2256) 4 41 7.7E-22 T 28-03-2018 IPR017136 Uncharacterised conserved protein UCP037205 MKLM6_RS19770 3f55b9f263e528450088b682fb221640 49 PIRSF PIRSF037205 1 49 3.1E-24 T 28-03-2018 IPR017136 Uncharacterised conserved protein UCP037205 MKLM6_RS19770 3f55b9f263e528450088b682fb221640 49 Gene3D G3DSA:3.30.50.10 6 45 1.5E-10 T 28-03-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 MKLM6_RS16420 d98b08a3456d71e38edcc124f7cb8877 243 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 2 236 1.1E-71 T 28-03-2018 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 MKLM6_RS16420 d98b08a3456d71e38edcc124f7cb8877 243 PIRSF PIRSF004808 1 243 2.1E-76 T 28-03-2018 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 MKLM6_RS16420 d98b08a3456d71e38edcc124f7cb8877 243 Pfam PF00588 SpoU rRNA Methylase family 5 156 4.1E-34 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MKLM6_RS16420 d98b08a3456d71e38edcc124f7cb8877 243 Gene3D G3DSA:3.40.1280.10 1 166 7.5E-44 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MKLM6_RS16420 d98b08a3456d71e38edcc124f7cb8877 243 SUPERFAMILY SSF75217 4 165 2.03E-38 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases MKLM6_RS16170 014e2587396ee5b7be938d28384379ff 190 SUPERFAMILY SSF46689 3 74 1.08E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS16170 014e2587396ee5b7be938d28384379ff 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MKLM6_RS16170 014e2587396ee5b7be938d28384379ff 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MKLM6_RS16170 014e2587396ee5b7be938d28384379ff 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 2.7E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MKLM6_RS16170 014e2587396ee5b7be938d28384379ff 190 SUPERFAMILY SSF48498 80 169 1.63E-15 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MKLM6_RS16170 014e2587396ee5b7be938d28384379ff 190 Gene3D G3DSA:1.10.357.10 60 186 3.0E-27 T 28-03-2018 MKLM6_RS16170 014e2587396ee5b7be938d28384379ff 190 Gene3D G3DSA:1.10.10.60 4 59 4.2E-15 T 28-03-2018 MKLM6_RS17820 b03f1287a30f7cd0b5cccc444a00bc84 438 Pfam PF03797 Autotransporter beta-domain 155 418 1.2E-39 T 28-03-2018 IPR005546 Autotransporter beta-domain MKLM6_RS17820 b03f1287a30f7cd0b5cccc444a00bc84 438 SMART SM00869 150 428 1.0E-30 T 28-03-2018 IPR005546 Autotransporter beta-domain MKLM6_RS17820 b03f1287a30f7cd0b5cccc444a00bc84 438 Gene3D G3DSA:2.40.128.130 81 438 1.4E-37 T 28-03-2018 MKLM6_RS17820 b03f1287a30f7cd0b5cccc444a00bc84 438 SUPERFAMILY SSF103515 143 438 1.02E-37 T 28-03-2018 IPR005546 Autotransporter beta-domain MKLM6_RS17820 b03f1287a30f7cd0b5cccc444a00bc84 438 SUPERFAMILY SSF103515 112 117 1.02E-37 T 28-03-2018 IPR005546 Autotransporter beta-domain MKLM6_RS12505 9a91de6f1302040eadfa033a5a13e7bf 462 Gene3D G3DSA:3.40.50.1220 287 461 3.8E-84 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MKLM6_RS12505 9a91de6f1302040eadfa033a5a13e7bf 462 SUPERFAMILY SSF52467 287 461 1.65E-73 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MKLM6_RS12505 9a91de6f1302040eadfa033a5a13e7bf 462 PIRSF PIRSF000204 1 462 1.1E-208 T 28-03-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 MKLM6_RS12505 9a91de6f1302040eadfa033a5a13e7bf 462 Pfam PF02233 NAD(P) transhydrogenase beta subunit 7 458 6.6E-194 T 28-03-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 MKLM6_RS18950 c7d7a91437b83921863656ef477ab81f 259 Pfam PF01816 Leucine rich repeat variant 142 164 4.8E-5 T 28-03-2018 IPR004830 Leucine rich repeat variant MKLM6_RS18950 c7d7a91437b83921863656ef477ab81f 259 Pfam PF05484 LRV protein FeS4 cluster 18 61 5.2E-13 T 28-03-2018 IPR008665 LRV FeS4 cluster MKLM6_RS18950 c7d7a91437b83921863656ef477ab81f 259 SUPERFAMILY SSF48371 29 239 3.84E-41 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 MKLM6_RS18950 c7d7a91437b83921863656ef477ab81f 259 Gene3D G3DSA:1.25.10.10 6 248 2.2E-29 T 28-03-2018 IPR011989 Armadillo-like helical MKLM6_RS20130 495d06a85ebbc338f1dbff117252647d 223 SUPERFAMILY SSF55469 8 221 2.22E-52 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MKLM6_RS20130 495d06a85ebbc338f1dbff117252647d 223 Gene3D G3DSA:3.40.109.10 5 223 2.8E-39 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MKLM6_RS20130 495d06a85ebbc338f1dbff117252647d 223 Pfam PF00881 Nitroreductase family 14 201 6.8E-24 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MKLM6_RS03540 7b8ba15d5a1f0dc33ae029350e805ec9 187 Pfam PF00227 Proteasome subunit 5 175 4.0E-24 T 28-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 MKLM6_RS03540 7b8ba15d5a1f0dc33ae029350e805ec9 187 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 177 6.2E-88 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 MKLM6_RS03540 7b8ba15d5a1f0dc33ae029350e805ec9 187 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 177 42.194 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 MKLM6_RS03540 7b8ba15d5a1f0dc33ae029350e805ec9 187 PIRSF PIRSF039093 1 180 5.3E-91 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 MKLM6_RS03540 7b8ba15d5a1f0dc33ae029350e805ec9 187 Gene3D G3DSA:3.60.20.10 7 179 2.3E-32 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MKLM6_RS03540 7b8ba15d5a1f0dc33ae029350e805ec9 187 SUPERFAMILY SSF56235 4 177 1.14E-61 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MKLM6_RS16735 821194ad240a9a9acb223bfb998e5fce 142 Pfam PF03459 TOBE domain 76 137 7.9E-19 T 28-03-2018 IPR005116 Transport-associated OB, type 1 MKLM6_RS16735 821194ad240a9a9acb223bfb998e5fce 142 Pfam PF03459 TOBE domain 3 64 1.2E-16 T 28-03-2018 IPR005116 Transport-associated OB, type 1 MKLM6_RS16735 821194ad240a9a9acb223bfb998e5fce 142 SUPERFAMILY SSF50331 74 140 3.61E-20 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal MKLM6_RS16735 821194ad240a9a9acb223bfb998e5fce 142 SUPERFAMILY SSF50331 1 69 1.46E-19 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal MKLM6_RS16735 821194ad240a9a9acb223bfb998e5fce 142 Gene3D G3DSA:2.40.50.100 73 141 1.2E-21 T 28-03-2018 MKLM6_RS16735 821194ad240a9a9acb223bfb998e5fce 142 Gene3D G3DSA:2.40.50.100 1 69 1.3E-21 T 28-03-2018 MKLM6_RS16735 821194ad240a9a9acb223bfb998e5fce 142 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 73 140 1.5E-21 T 28-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 MKLM6_RS16735 821194ad240a9a9acb223bfb998e5fce 142 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 1 68 9.3E-24 T 28-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 MKLM6_RS16875 8f577b566d022cfbea60a8f0dbd8307b 719 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 604 710 8.1E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS16875 8f577b566d022cfbea60a8f0dbd8307b 719 PRINTS PR00344 Bacterial sensor protein C-terminal signature 662 672 7.2E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS16875 8f577b566d022cfbea60a8f0dbd8307b 719 PRINTS PR00344 Bacterial sensor protein C-terminal signature 644 658 7.2E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS16875 8f577b566d022cfbea60a8f0dbd8307b 719 PRINTS PR00344 Bacterial sensor protein C-terminal signature 673 691 7.2E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS16875 8f577b566d022cfbea60a8f0dbd8307b 719 PRINTS PR00344 Bacterial sensor protein C-terminal signature 697 710 7.2E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MKLM6_RS16875 8f577b566d022cfbea60a8f0dbd8307b 719 SMART SM00304 304 356 3.8E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS16875 8f577b566d022cfbea60a8f0dbd8307b 719 Pfam PF08448 PAS fold 377 485 2.2E-7 T 28-03-2018 IPR013656 PAS fold-4 MKLM6_RS16875 8f577b566d022cfbea60a8f0dbd8307b 719 SMART SM00387 603 713 7.7E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS16875 8f577b566d022cfbea60a8f0dbd8307b 719 SUPERFAMILY SSF55874 556 712 9.69E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS16875 8f577b566d022cfbea60a8f0dbd8307b 719 Gene3D G3DSA:3.30.565.10 565 713 4.5E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS16875 8f577b566d022cfbea60a8f0dbd8307b 719 Pfam PF00672 HAMP domain 304 352 8.4E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS16875 8f577b566d022cfbea60a8f0dbd8307b 719 SUPERFAMILY SSF158472 304 353 3.53E-9 T 28-03-2018 MKLM6_RS16875 8f577b566d022cfbea60a8f0dbd8307b 719 SUPERFAMILY SSF47384 488 564 5.69E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS16875 8f577b566d022cfbea60a8f0dbd8307b 719 SUPERFAMILY SSF55785 358 483 8.76E-13 T 28-03-2018 IPR000014 PAS domain MKLM6_RS16875 8f577b566d022cfbea60a8f0dbd8307b 719 Gene3D G3DSA:1.10.287.130 488 561 3.7E-12 T 28-03-2018 MKLM6_RS16875 8f577b566d022cfbea60a8f0dbd8307b 719 Gene3D G3DSA:3.30.450.20 117 246 2.2E-4 T 28-03-2018 MKLM6_RS16875 8f577b566d022cfbea60a8f0dbd8307b 719 Pfam PF00512 His Kinase A (phospho-acceptor) domain 494 561 1.6E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS16875 8f577b566d022cfbea60a8f0dbd8307b 719 PIRSF PIRSF037532 2 715 5.7E-217 T 28-03-2018 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator MKLM6_RS16875 8f577b566d022cfbea60a8f0dbd8307b 719 Gene3D G3DSA:3.30.450.20 349 487 7.1E-19 T 28-03-2018 MKLM6_RS16875 8f577b566d022cfbea60a8f0dbd8307b 719 SMART SM00388 493 565 3.9E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS05780 f954d71ba4b37a03fbdbbe853cfb48f3 214 SUPERFAMILY SSF49879 3 93 2.26E-15 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MKLM6_RS05780 f954d71ba4b37a03fbdbbe853cfb48f3 214 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 21 90 4.4E-8 T 28-03-2018 IPR032030 YscD, cytoplasmic domain MKLM6_RS05780 f954d71ba4b37a03fbdbbe853cfb48f3 214 SUPERFAMILY SSF49879 132 213 3.39E-7 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MKLM6_RS05780 f954d71ba4b37a03fbdbbe853cfb48f3 214 Gene3D G3DSA:2.60.200.20 117 213 0.0011 T 28-03-2018 MKLM6_RS05780 f954d71ba4b37a03fbdbbe853cfb48f3 214 Gene3D G3DSA:2.60.200.20 3 103 2.7E-12 T 28-03-2018 MKLM6_RS06375 5ca2e421d5f4f5d3297b4155b1f28cdf 367 TIGRFAM TIGR03470 HpnH: hopanoid biosynthesis associated radical SAM protein HpnH 2 319 3.7E-167 T 28-03-2018 IPR017833 Hopanoid biosynthesis associated radical SAM protein HpnH MKLM6_RS06375 5ca2e421d5f4f5d3297b4155b1f28cdf 367 Pfam PF11946 Domain of unknown function (DUF3463) 195 328 4.1E-56 T 28-03-2018 IPR022563 Domain of unknown function DUF3463 MKLM6_RS06375 5ca2e421d5f4f5d3297b4155b1f28cdf 367 Gene3D G3DSA:3.20.20.70 16 319 1.6E-32 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS06375 5ca2e421d5f4f5d3297b4155b1f28cdf 367 Pfam PF04055 Radical SAM superfamily 34 186 7.2E-16 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS06375 5ca2e421d5f4f5d3297b4155b1f28cdf 367 SUPERFAMILY SSF102114 24 308 2.62E-54 T 28-03-2018 MKLM6_RS18305 0aef7e7d42f7ec58fde4c11cb9873176 187 SUPERFAMILY SSF52141 7 167 1.18E-32 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MKLM6_RS18305 0aef7e7d42f7ec58fde4c11cb9873176 187 Pfam PF03167 Uracil DNA glycosylase superfamily 13 165 1.2E-7 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MKLM6_RS18305 0aef7e7d42f7ec58fde4c11cb9873176 187 Gene3D G3DSA:3.40.470.10 3 177 4.7E-45 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MKLM6_RS18305 0aef7e7d42f7ec58fde4c11cb9873176 187 TIGRFAM TIGR04274 hypoxanDNAglyco: DNA-deoxyinosine glycosylase 6 163 5.8E-48 T 28-03-2018 IPR026353 Hypoxanthine-DNA glycosylase MKLM6_RS14740 4fe22f0e3fdab2e57e1cb50a7043eb87 101 Pfam PF10052 Protein of unknown function (DUF2288) 10 98 1.2E-29 T 28-03-2018 IPR018741 Protein of unknown function DUF2288 MKLM6_RS00995 e837a05e4c629c1775c95d615ee388bf 334 Pfam PF00348 Polyprenyl synthetase 44 284 5.6E-76 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 MKLM6_RS00995 e837a05e4c629c1775c95d615ee388bf 334 Gene3D G3DSA:1.10.600.10 2 334 5.3E-101 T 28-03-2018 IPR008949 Isoprenoid synthase domain MKLM6_RS00995 e837a05e4c629c1775c95d615ee388bf 334 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 93 107 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site MKLM6_RS00995 e837a05e4c629c1775c95d615ee388bf 334 SUPERFAMILY SSF48576 15 333 1.76E-99 T 28-03-2018 IPR008949 Isoprenoid synthase domain MKLM6_RS08075 899bc562e72cfa48197fc75a6e9a2323 96 Gene3D G3DSA:3.30.460.10 1 95 1.1E-19 T 28-03-2018 MKLM6_RS08075 899bc562e72cfa48197fc75a6e9a2323 96 Pfam PF01909 Nucleotidyltransferase domain 14 88 2.3E-13 T 28-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 MKLM6_RS08075 899bc562e72cfa48197fc75a6e9a2323 96 SUPERFAMILY SSF81301 1 92 2.22E-23 T 28-03-2018 MKLM6_RS02705 d810471d113eb336effa6d5520e9c4f7 179 Pfam PF03748 Flagellar basal body-associated protein FliL 78 179 1.3E-19 T 28-03-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 MKLM6_RS19430 ecf08e79662926f99dc1efa304f9bffb 109 Gene3D G3DSA:1.10.10.370 40 108 9.9E-29 T 28-03-2018 MKLM6_RS19430 ecf08e79662926f99dc1efa304f9bffb 109 Gene3D G3DSA:3.30.1420.10 2 39 3.4E-10 T 28-03-2018 MKLM6_RS19430 ecf08e79662926f99dc1efa304f9bffb 109 PIRSF PIRSF006223 2 109 6.5E-36 T 28-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE MKLM6_RS19430 ecf08e79662926f99dc1efa304f9bffb 109 SUPERFAMILY SSF69721 2 109 3.53E-34 T 28-03-2018 IPR025526 DsrC-like domain MKLM6_RS19430 ecf08e79662926f99dc1efa304f9bffb 109 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 4 109 2.6E-40 T 28-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE MKLM6_RS19430 ecf08e79662926f99dc1efa304f9bffb 109 Pfam PF04358 DsrC like protein 5 109 1.3E-38 T 28-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE MKLM6_RS19785 1a3c9e0df332fc4751692e92a949162c 377 Gene3D G3DSA:2.40.10.10 56 165 1.1E-32 T 28-03-2018 MKLM6_RS19785 1a3c9e0df332fc4751692e92a949162c 377 Pfam PF13365 Trypsin-like peptidase domain 97 235 6.3E-36 T 28-03-2018 MKLM6_RS19785 1a3c9e0df332fc4751692e92a949162c 377 SUPERFAMILY SSF50494 61 270 4.66E-61 T 28-03-2018 IPR009003 Peptidase S1, PA clan MKLM6_RS19785 1a3c9e0df332fc4751692e92a949162c 377 Pfam PF13180 PDZ domain 274 373 5.0E-14 T 28-03-2018 IPR001478 PDZ domain GO:0005515 MKLM6_RS19785 1a3c9e0df332fc4751692e92a949162c 377 PRINTS PR00834 HtrA/DegQ protease family signature 228 245 8.1E-51 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MKLM6_RS19785 1a3c9e0df332fc4751692e92a949162c 377 PRINTS PR00834 HtrA/DegQ protease family signature 322 334 8.1E-51 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MKLM6_RS19785 1a3c9e0df332fc4751692e92a949162c 377 PRINTS PR00834 HtrA/DegQ protease family signature 127 147 8.1E-51 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MKLM6_RS19785 1a3c9e0df332fc4751692e92a949162c 377 PRINTS PR00834 HtrA/DegQ protease family signature 169 193 8.1E-51 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MKLM6_RS19785 1a3c9e0df332fc4751692e92a949162c 377 PRINTS PR00834 HtrA/DegQ protease family signature 206 223 8.1E-51 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MKLM6_RS19785 1a3c9e0df332fc4751692e92a949162c 377 PRINTS PR00834 HtrA/DegQ protease family signature 106 118 8.1E-51 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MKLM6_RS19785 1a3c9e0df332fc4751692e92a949162c 377 Gene3D G3DSA:2.40.10.10 166 264 2.2E-39 T 28-03-2018 MKLM6_RS19785 1a3c9e0df332fc4751692e92a949162c 377 SMART SM00228 274 364 1.9E-7 T 28-03-2018 IPR001478 PDZ domain GO:0005515 MKLM6_RS19785 1a3c9e0df332fc4751692e92a949162c 377 SUPERFAMILY SSF50156 232 364 3.68E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 MKLM6_RS19785 1a3c9e0df332fc4751692e92a949162c 377 Gene3D G3DSA:2.30.42.10 272 377 2.4E-20 T 28-03-2018 MKLM6_RS20975 d341f673b0f906b3d319657a4e2804d0 171 Gene3D G3DSA:1.10.10.10 76 169 3.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS20975 d341f673b0f906b3d319657a4e2804d0 171 Gene3D G3DSA:1.10.1740.10 5 75 1.2E-13 T 28-03-2018 MKLM6_RS20975 d341f673b0f906b3d319657a4e2804d0 171 Pfam PF08281 Sigma-70, region 4 111 162 1.4E-14 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS20975 d341f673b0f906b3d319657a4e2804d0 171 SUPERFAMILY SSF88659 87 167 2.83E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS20975 d341f673b0f906b3d319657a4e2804d0 171 Pfam PF04542 Sigma-70 region 2 16 79 1.0E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS20975 d341f673b0f906b3d319657a4e2804d0 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 166 6.8E-28 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS20975 d341f673b0f906b3d319657a4e2804d0 171 SUPERFAMILY SSF88946 15 94 1.18E-14 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MKLM6_RS21100 6c1c4e56e1054be2906125ab58a82441 378 Pfam PF03739 Predicted permease YjgP/YjgQ family 23 361 9.5E-57 T 28-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 MKLM6_RS21100 6c1c4e56e1054be2906125ab58a82441 378 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 20 360 7.2E-93 T 28-03-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 MKLM6_RS16995 0476ca92e0543a4b8b426be2139e560a 462 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 11 445 8.5E-88 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 MKLM6_RS16995 0476ca92e0543a4b8b426be2139e560a 462 SUPERFAMILY SSF56954 7 446 3.4E-87 T 28-03-2018 MKLM6_RS16995 0476ca92e0543a4b8b426be2139e560a 462 Gene3D G3DSA:1.20.1600.10 19 450 5.6E-82 T 28-03-2018 MKLM6_RS16995 0476ca92e0543a4b8b426be2139e560a 462 Pfam PF02321 Outer membrane efflux protein 268 443 2.1E-21 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS16995 0476ca92e0543a4b8b426be2139e560a 462 Pfam PF02321 Outer membrane efflux protein 60 241 4.6E-19 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS02455 f409701b7956c271e2bff95ef75effe3 253 Gene3D G3DSA:1.10.3720.10 10 251 1.0E-26 T 28-03-2018 MKLM6_RS02455 f409701b7956c271e2bff95ef75effe3 253 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 233 6.8E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MKLM6_RS02455 f409701b7956c271e2bff95ef75effe3 253 SUPERFAMILY SSF161098 54 239 3.01E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MKLM6_RS06075 02e06973d2057d70baf784a306a91cce 259 PRINTS PR01805 VacJ lipoprotein signature 49 65 2.9E-26 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 MKLM6_RS06075 02e06973d2057d70baf784a306a91cce 259 PRINTS PR01805 VacJ lipoprotein signature 100 117 2.9E-26 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 MKLM6_RS06075 02e06973d2057d70baf784a306a91cce 259 PRINTS PR01805 VacJ lipoprotein signature 136 153 2.9E-26 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 MKLM6_RS06075 02e06973d2057d70baf784a306a91cce 259 PRINTS PR01805 VacJ lipoprotein signature 32 45 2.9E-26 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 MKLM6_RS06075 02e06973d2057d70baf784a306a91cce 259 Pfam PF04333 MlaA lipoprotein 31 231 3.9E-72 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 MKLM6_RS11775 790dc0dff1f4aa63e3e8b1d825dfa787 165 Gene3D G3DSA:3.30.530.20 8 156 4.2E-12 T 28-03-2018 IPR023393 START-like domain MKLM6_RS11775 790dc0dff1f4aa63e3e8b1d825dfa787 165 SUPERFAMILY SSF55961 15 155 8.85E-12 T 28-03-2018 MKLM6_RS11775 790dc0dff1f4aa63e3e8b1d825dfa787 165 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 14 146 1.5E-7 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase MKLM6_RS05585 075f5cdb921f57c13297d2c03d217975 158 Pfam PF10387 Protein of unknown function (DUF2442) 3 75 2.3E-10 T 28-03-2018 IPR018841 Protein of unknown function DUF2442 MKLM6_RS05585 075f5cdb921f57c13297d2c03d217975 158 SUPERFAMILY SSF143880 2 79 5.23E-15 T 28-03-2018 IPR018841 Protein of unknown function DUF2442 MKLM6_RS05585 075f5cdb921f57c13297d2c03d217975 158 Gene3D G3DSA:3.30.2020.10 1 78 3.0E-16 T 28-03-2018 IPR018841 Protein of unknown function DUF2442 MKLM6_RS05585 075f5cdb921f57c13297d2c03d217975 158 Gene3D G3DSA:1.10.260.40 80 158 1.4E-8 T 28-03-2018 MKLM6_RS05585 075f5cdb921f57c13297d2c03d217975 158 SUPERFAMILY SSF47413 85 146 5.16E-21 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MKLM6_RS03495 d23061209fa46aad2b36f6f23e6bf570 522 SUPERFAMILY SSF56935 314 522 2.11E-18 T 28-03-2018 MKLM6_RS03495 d23061209fa46aad2b36f6f23e6bf570 522 SUPERFAMILY SSF56935 140 274 2.11E-18 T 28-03-2018 MKLM6_RS03495 d23061209fa46aad2b36f6f23e6bf570 522 Pfam PF02530 Porin subfamily 130 249 7.4E-5 T 28-03-2018 IPR003684 Porin, alpha proteobacteria type GO:0006810|GO:0015288|GO:0016020 MKLM6_RS03495 d23061209fa46aad2b36f6f23e6bf570 522 Pfam PF02530 Porin subfamily 331 493 2.5E-8 T 28-03-2018 IPR003684 Porin, alpha proteobacteria type GO:0006810|GO:0015288|GO:0016020 MKLM6_RS03495 d23061209fa46aad2b36f6f23e6bf570 522 Gene3D G3DSA:2.40.160.10 106 522 4.6E-16 T 28-03-2018 MKLM6_RS18875 89c8cf9406c0ba1f3a323d80c4898927 95 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 9.2E-27 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 MKLM6_RS18875 89c8cf9406c0ba1f3a323d80c4898927 95 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 21 90 1.1E-15 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 MKLM6_RS18875 89c8cf9406c0ba1f3a323d80c4898927 95 SUPERFAMILY SSF141000 3 93 1.44E-27 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 MKLM6_RS18875 89c8cf9406c0ba1f3a323d80c4898927 95 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 21.779 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 MKLM6_RS20865 2709318e87187a9d17e423cbcc65d3a8 187 Pfam PF09335 SNARE associated Golgi protein 26 146 7.2E-20 T 28-03-2018 IPR032816 SNARE associated Golgi protein MKLM6_RS22705 f70114ff157e6d9ea313e018e6ea7c72 161 Gene3D G3DSA:2.10.109.10 42 161 2.4E-27 T 28-03-2018 MKLM6_RS22705 f70114ff157e6d9ea313e018e6ea7c72 161 Pfam PF00717 Peptidase S24-like 78 143 1.0E-11 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MKLM6_RS22705 f70114ff157e6d9ea313e018e6ea7c72 161 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 85 96 3.3E-7 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MKLM6_RS22705 f70114ff157e6d9ea313e018e6ea7c72 161 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 113 125 3.3E-7 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MKLM6_RS22705 f70114ff157e6d9ea313e018e6ea7c72 161 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 74 84 3.3E-7 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MKLM6_RS22705 f70114ff157e6d9ea313e018e6ea7c72 161 SUPERFAMILY SSF51306 36 159 1.92E-35 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MKLM6_RS08610 c15942b2cf3f5c25fedf8a3fd7cef313 336 Pfam PF07589 PEP-CTERM motif 308 331 4.9E-5 T 28-03-2018 IPR013424 PEP-CTERM protein-sorting domain MKLM6_RS08610 c15942b2cf3f5c25fedf8a3fd7cef313 336 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 309 331 1.2E-4 T 28-03-2018 IPR013424 PEP-CTERM protein-sorting domain MKLM6_RS16175 c6b4b3e1499c6ed40a7a66187c58c159 271 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 198 0.0013 T 28-03-2018 MKLM6_RS16175 c6b4b3e1499c6ed40a7a66187c58c159 271 Pfam PF00106 short chain dehydrogenase 8 188 3.7E-50 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS16175 c6b4b3e1499c6ed40a7a66187c58c159 271 Gene3D G3DSA:3.40.50.720 6 267 2.4E-59 T 28-03-2018 MKLM6_RS16175 c6b4b3e1499c6ed40a7a66187c58c159 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 7.5E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS16175 c6b4b3e1499c6ed40a7a66187c58c159 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 7.5E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS16175 c6b4b3e1499c6ed40a7a66187c58c159 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 7.5E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS16175 c6b4b3e1499c6ed40a7a66187c58c159 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 9.5E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS16175 c6b4b3e1499c6ed40a7a66187c58c159 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 9.5E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS16175 c6b4b3e1499c6ed40a7a66187c58c159 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 9.5E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS16175 c6b4b3e1499c6ed40a7a66187c58c159 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 9.5E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS16175 c6b4b3e1499c6ed40a7a66187c58c159 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 9.5E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MKLM6_RS16175 c6b4b3e1499c6ed40a7a66187c58c159 271 SUPERFAMILY SSF51735 2 266 1.91E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS00980 03ff35025d54360633e05facd71d3907 622 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 136 589 56.051 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MKLM6_RS00980 03ff35025d54360633e05facd71d3907 622 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 136 586 4.3E-214 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MKLM6_RS00980 03ff35025d54360633e05facd71d3907 622 Pfam PF13667 ThiC-associated domain 20 97 1.7E-32 T 28-03-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MKLM6_RS00980 03ff35025d54360633e05facd71d3907 622 Pfam PF01964 Radical SAM ThiC family 138 583 3.6E-198 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MKLM6_RS11950 df02be4f6bc5009da2a4a2d7a7de5efc 336 SMART SM01329 3 331 6.3E-184 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MKLM6_RS11950 df02be4f6bc5009da2a4a2d7a7de5efc 336 SUPERFAMILY SSF53659 2 335 8.83E-128 T 28-03-2018 MKLM6_RS11950 df02be4f6bc5009da2a4a2d7a7de5efc 336 Gene3D G3DSA:3.40.718.10 1 336 3.6E-138 T 28-03-2018 MKLM6_RS11950 df02be4f6bc5009da2a4a2d7a7de5efc 336 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 3 331 6.1E-110 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MKLM6_RS11950 df02be4f6bc5009da2a4a2d7a7de5efc 336 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 225 244 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 MKLM6_RS09245 958cbb30ab914b06840d69a0db2d80e9 311 SUPERFAMILY SSF53448 11 251 4.73E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS09245 958cbb30ab914b06840d69a0db2d80e9 311 Pfam PF00535 Glycosyl transferase family 2 16 119 1.3E-13 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MKLM6_RS09245 958cbb30ab914b06840d69a0db2d80e9 311 Gene3D G3DSA:3.90.550.10 8 218 5.8E-22 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS18205 56eec30e4c13bced84f0d58e24f4d19c 532 Pfam PF09423 PhoD-like phosphatase 145 503 6.5E-80 T 28-03-2018 IPR018946 Alkaline phosphatase D-related MKLM6_RS18205 56eec30e4c13bced84f0d58e24f4d19c 532 SUPERFAMILY SSF56300 134 518 1.52E-33 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS18205 56eec30e4c13bced84f0d58e24f4d19c 532 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 39 130 1.4E-11 T 28-03-2018 IPR032093 Phospholipase D, N-terminal MKLM6_RS18205 56eec30e4c13bced84f0d58e24f4d19c 532 Gene3D G3DSA:3.60.21.10 134 532 1.5E-31 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS18700 403cfca39cafb41e0f1a18703d9de033 282 Gene3D G3DSA:3.40.50.300 12 281 4.2E-6 T 28-03-2018 MKLM6_RS18700 403cfca39cafb41e0f1a18703d9de033 282 SUPERFAMILY SSF52540 15 46 3.94E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS18700 403cfca39cafb41e0f1a18703d9de033 282 SUPERFAMILY SSF52540 112 217 3.94E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS02130 2a91aa9ccb4e371a50290d3db59b7cab 304 Pfam PF01882 Protein of unknown function DUF58 53 136 5.4E-23 T 28-03-2018 IPR002881 Domain of unknown function DUF58 MKLM6_RS02130 2a91aa9ccb4e371a50290d3db59b7cab 304 Gene3D G3DSA:3.40.50.410 64 271 3.1E-20 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS02130 2a91aa9ccb4e371a50290d3db59b7cab 304 SUPERFAMILY SSF53300 88 228 1.41E-6 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS20300 e82e392c9f5ef392ab4ecec4d9cba7e3 346 Pfam PF06812 ImpA, N-terminal, type VI secretion system 8 129 8.5E-32 T 28-03-2018 IPR010657 ImpA, N-terminal MKLM6_RS20300 e82e392c9f5ef392ab4ecec4d9cba7e3 346 TIGRFAM TIGR03363 VI_chp_8: type VI secretion-associated protein, ImpA family 3 339 4.8E-64 T 28-03-2018 IPR017740 Type VI secretion system-associated, ImpA MKLM6_RS20415 800c0509be3de522ad2f7cb6ed771f0d 353 PIRSF PIRSF019169 1 353 1.1E-126 T 28-03-2018 IPR005883 Type IV pilus assembly protein PilM MKLM6_RS20415 800c0509be3de522ad2f7cb6ed771f0d 353 Gene3D G3DSA:3.30.420.40 299 353 2.1E-5 T 28-03-2018 MKLM6_RS20415 800c0509be3de522ad2f7cb6ed771f0d 353 Gene3D G3DSA:3.30.420.40 1 170 2.8E-36 T 28-03-2018 MKLM6_RS20415 800c0509be3de522ad2f7cb6ed771f0d 353 SUPERFAMILY SSF53067 58 174 2.94E-12 T 28-03-2018 MKLM6_RS20415 800c0509be3de522ad2f7cb6ed771f0d 353 Pfam PF11104 Type IV pilus assembly protein PilM; 13 352 2.9E-138 T 28-03-2018 IPR005883 Type IV pilus assembly protein PilM MKLM6_RS20415 800c0509be3de522ad2f7cb6ed771f0d 353 SMART SM00842 11 178 0.0018 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 MKLM6_RS20415 800c0509be3de522ad2f7cb6ed771f0d 353 TIGRFAM TIGR01175 pilM: type IV pilus assembly protein PilM 9 352 2.7E-122 T 28-03-2018 IPR005883 Type IV pilus assembly protein PilM MKLM6_RS20415 800c0509be3de522ad2f7cb6ed771f0d 353 Gene3D G3DSA:3.30.420.40 187 298 7.4E-7 T 28-03-2018 MKLM6_RS20415 800c0509be3de522ad2f7cb6ed771f0d 353 SUPERFAMILY SSF53067 191 351 2.53E-23 T 28-03-2018 MKLM6_RS15000 59dfaca0540bebfb248f78c8b60839f2 346 Gene3D G3DSA:3.90.650.10 173 344 6.9E-67 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MKLM6_RS15000 59dfaca0540bebfb248f78c8b60839f2 346 SUPERFAMILY SSF56042 173 340 2.69E-63 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MKLM6_RS15000 59dfaca0540bebfb248f78c8b60839f2 346 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 8 345 46.911 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MKLM6_RS15000 59dfaca0540bebfb248f78c8b60839f2 346 SUPERFAMILY SSF55326 9 172 1.94E-50 T 28-03-2018 IPR016188 PurM-like, N-terminal domain MKLM6_RS15000 59dfaca0540bebfb248f78c8b60839f2 346 Gene3D G3DSA:3.30.1330.10 34 163 2.4E-52 T 28-03-2018 IPR016188 PurM-like, N-terminal domain MKLM6_RS15000 59dfaca0540bebfb248f78c8b60839f2 346 Pfam PF02769 AIR synthase related protein, C-terminal domain 178 339 6.1E-39 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MKLM6_RS15000 59dfaca0540bebfb248f78c8b60839f2 346 Pfam PF00586 AIR synthase related protein, N-terminal domain 55 166 1.6E-15 T 28-03-2018 IPR016188 PurM-like, N-terminal domain MKLM6_RS15000 59dfaca0540bebfb248f78c8b60839f2 346 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 9 336 8.2E-140 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MKLM6_RS07255 a4f3cdf5725204887982fe7043fc10e3 596 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 1 586 33.536 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 MKLM6_RS07255 a4f3cdf5725204887982fe7043fc10e3 596 Gene3D G3DSA:3.30.930.10 133 588 9.2E-107 T 28-03-2018 MKLM6_RS07255 a4f3cdf5725204887982fe7043fc10e3 596 SUPERFAMILY SSF55681 427 587 4.61E-106 T 28-03-2018 MKLM6_RS07255 a4f3cdf5725204887982fe7043fc10e3 596 SUPERFAMILY SSF55681 115 294 4.61E-106 T 28-03-2018 MKLM6_RS07255 a4f3cdf5725204887982fe7043fc10e3 596 PRINTS PR01042 Aspartyl-tRNA synthetase signature 476 492 5.6E-27 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS07255 a4f3cdf5725204887982fe7043fc10e3 596 PRINTS PR01042 Aspartyl-tRNA synthetase signature 520 534 5.6E-27 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS07255 a4f3cdf5725204887982fe7043fc10e3 596 PRINTS PR01042 Aspartyl-tRNA synthetase signature 192 204 5.6E-27 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS07255 a4f3cdf5725204887982fe7043fc10e3 596 PRINTS PR01042 Aspartyl-tRNA synthetase signature 209 222 5.6E-27 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS07255 a4f3cdf5725204887982fe7043fc10e3 596 SUPERFAMILY SSF50249 1 105 9.71E-35 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold MKLM6_RS07255 a4f3cdf5725204887982fe7043fc10e3 596 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 586 5.4E-241 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 MKLM6_RS07255 a4f3cdf5725204887982fe7043fc10e3 596 Pfam PF01336 OB-fold nucleic acid binding domain 18 102 4.5E-17 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MKLM6_RS07255 a4f3cdf5725204887982fe7043fc10e3 596 Pfam PF00152 tRNA synthetases class II (D, K and N) 119 560 1.0E-107 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS07255 a4f3cdf5725204887982fe7043fc10e3 596 Gene3D G3DSA:2.40.50.140 1 108 5.9E-30 T 28-03-2018 MKLM6_RS07255 a4f3cdf5725204887982fe7043fc10e3 596 SUPERFAMILY SSF55261 292 422 7.63E-41 T 28-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 MKLM6_RS07255 a4f3cdf5725204887982fe7043fc10e3 596 Pfam PF02938 GAD domain 310 409 4.0E-26 T 28-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 MKLM6_RS13785 50a57f19af8dbaa7251add583f06d38f 325 SMART SM00829 10 323 1.1E-64 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MKLM6_RS13785 50a57f19af8dbaa7251add583f06d38f 325 Pfam PF00107 Zinc-binding dehydrogenase 151 276 2.8E-33 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MKLM6_RS13785 50a57f19af8dbaa7251add583f06d38f 325 SUPERFAMILY SSF50129 1 140 3.35E-38 T 28-03-2018 IPR011032 GroES-like MKLM6_RS13785 50a57f19af8dbaa7251add583f06d38f 325 Gene3D G3DSA:3.90.180.10 1 132 6.2E-39 T 28-03-2018 MKLM6_RS13785 50a57f19af8dbaa7251add583f06d38f 325 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 324 1.2E-149 T 28-03-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 MKLM6_RS13785 50a57f19af8dbaa7251add583f06d38f 325 Gene3D G3DSA:3.40.50.720 133 309 4.5E-45 T 28-03-2018 MKLM6_RS13785 50a57f19af8dbaa7251add583f06d38f 325 SUPERFAMILY SSF51735 111 287 2.85E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS13785 50a57f19af8dbaa7251add583f06d38f 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 99 2.0E-9 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MKLM6_RS03130 e9273d13357157547e92083d719bb569 245 Gene3D G3DSA:2.70.98.10 5 169 0.0027 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 MKLM6_RS03130 e9273d13357157547e92083d719bb569 245 SUPERFAMILY SSF74650 8 205 8.37E-8 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 MKLM6_RS17775 6365c180ad2c239d7f47e518ada32e71 85 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 49 7.0E-15 T 28-03-2018 MKLM6_RS17775 6365c180ad2c239d7f47e518ada32e71 85 SUPERFAMILY SSF143120 1 48 4.19E-13 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MKLM6_RS17775 6365c180ad2c239d7f47e518ada32e71 85 Gene3D G3DSA:3.40.1620.10 1 51 8.1E-16 T 28-03-2018 MKLM6_RS17775 6365c180ad2c239d7f47e518ada32e71 85 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 67 2.3E-18 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MKLM6_RS05025 d25dea3adde036cda708d19e85115112 95 Pfam PF05598 Transposase domain (DUF772) 20 85 1.0E-19 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS06350 4682b46b18a72c2d9a529dfa6049526e 119 Pfam PF04234 CopC domain 22 115 6.0E-9 T 28-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 MKLM6_RS06350 4682b46b18a72c2d9a529dfa6049526e 119 SUPERFAMILY SSF81296 39 116 1.47E-7 T 28-03-2018 IPR014756 Immunoglobulin E-set MKLM6_RS06350 4682b46b18a72c2d9a529dfa6049526e 119 Gene3D G3DSA:2.60.40.1220 21 116 2.5E-8 T 28-03-2018 MKLM6_RS17050 96fd9bbb6f8b80134b7f6602cb6d995e 1511 Gene3D G3DSA:2.40.128.130 1110 1511 5.1E-41 T 28-03-2018 MKLM6_RS17050 96fd9bbb6f8b80134b7f6602cb6d995e 1511 SUPERFAMILY SSF51126 541 676 4.71E-5 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS17050 96fd9bbb6f8b80134b7f6602cb6d995e 1511 SUPERFAMILY SSF51126 107 487 4.08E-13 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor MKLM6_RS17050 96fd9bbb6f8b80134b7f6602cb6d995e 1511 SMART SM00869 1228 1500 3.1E-26 T 28-03-2018 IPR005546 Autotransporter beta-domain MKLM6_RS17050 96fd9bbb6f8b80134b7f6602cb6d995e 1511 Pfam PF12951 Passenger-associated-transport-repeat 315 342 8.0E-7 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat MKLM6_RS17050 96fd9bbb6f8b80134b7f6602cb6d995e 1511 Pfam PF12951 Passenger-associated-transport-repeat 605 630 1.1E-5 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat MKLM6_RS17050 96fd9bbb6f8b80134b7f6602cb6d995e 1511 Pfam PF12951 Passenger-associated-transport-repeat 121 148 2.1E-6 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat MKLM6_RS17050 96fd9bbb6f8b80134b7f6602cb6d995e 1511 Pfam PF12951 Passenger-associated-transport-repeat 218 245 1.5E-6 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat MKLM6_RS17050 96fd9bbb6f8b80134b7f6602cb6d995e 1511 Pfam PF12951 Passenger-associated-transport-repeat 412 439 4.4E-5 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat MKLM6_RS17050 96fd9bbb6f8b80134b7f6602cb6d995e 1511 Pfam PF12951 Passenger-associated-transport-repeat 509 536 1.0E-6 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat MKLM6_RS17050 96fd9bbb6f8b80134b7f6602cb6d995e 1511 SUPERFAMILY SSF103515 1225 1511 5.1E-39 T 28-03-2018 IPR005546 Autotransporter beta-domain MKLM6_RS17050 96fd9bbb6f8b80134b7f6602cb6d995e 1511 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 509 537 1.7E-8 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat MKLM6_RS17050 96fd9bbb6f8b80134b7f6602cb6d995e 1511 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 412 440 4.4E-7 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat MKLM6_RS17050 96fd9bbb6f8b80134b7f6602cb6d995e 1511 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 602 632 5.4E-10 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat MKLM6_RS17050 96fd9bbb6f8b80134b7f6602cb6d995e 1511 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 121 149 8.2E-9 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat MKLM6_RS17050 96fd9bbb6f8b80134b7f6602cb6d995e 1511 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 315 343 1.3E-8 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat MKLM6_RS17050 96fd9bbb6f8b80134b7f6602cb6d995e 1511 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 218 246 3.9E-9 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat MKLM6_RS17050 96fd9bbb6f8b80134b7f6602cb6d995e 1511 Pfam PF03797 Autotransporter beta-domain 1231 1490 2.7E-41 T 28-03-2018 IPR005546 Autotransporter beta-domain MKLM6_RS12115 da5dd6026b3640fafaa4dcaa77fed0e6 92 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 34 85 3.5E-10 T 28-03-2018 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter MKLM6_RS10775 c474c1e3be9174d28d7b13660d21eae8 239 Pfam PF01738 Dienelactone hydrolase family 27 237 5.5E-42 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 MKLM6_RS10775 c474c1e3be9174d28d7b13660d21eae8 239 SUPERFAMILY SSF53474 12 236 3.13E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS10775 c474c1e3be9174d28d7b13660d21eae8 239 Gene3D G3DSA:3.40.50.1820 4 239 9.4E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS22660 1dd184d36551783e1af3afaa6432d024 297 SUPERFAMILY SSF53474 75 227 3.0E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS22660 1dd184d36551783e1af3afaa6432d024 297 Gene3D G3DSA:3.40.50.1820 66 289 9.7E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS15975 6d6839a72a6ee942a1f2f6c6a2e6f4a9 117 SUPERFAMILY SSF47413 58 115 2.96E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MKLM6_RS15975 6d6839a72a6ee942a1f2f6c6a2e6f4a9 117 SMART SM00530 60 114 6.1E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MKLM6_RS15975 6d6839a72a6ee942a1f2f6c6a2e6f4a9 117 Gene3D G3DSA:1.10.260.40 7 116 1.6E-7 T 28-03-2018 MKLM6_RS05835 61f65c4b138f9bfd14f2a5c3b90c1573 286 Pfam PF01261 Xylose isomerase-like TIM barrel 32 224 5.7E-24 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MKLM6_RS05835 61f65c4b138f9bfd14f2a5c3b90c1573 286 SUPERFAMILY SSF51658 9 260 1.83E-52 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MKLM6_RS05835 61f65c4b138f9bfd14f2a5c3b90c1573 286 Gene3D G3DSA:3.20.20.150 7 286 2.1E-48 T 28-03-2018 MKLM6_RS11345 b6c473e3b468d005f7087576bdec5f68 387 Pfam PF05137 Fimbrial assembly protein (PilN) 285 357 6.4E-10 T 28-03-2018 IPR007813 Fimbrial assembly PilN MKLM6_RS11345 b6c473e3b468d005f7087576bdec5f68 387 SUPERFAMILY SSF53067 66 179 5.96E-10 T 28-03-2018 MKLM6_RS11345 b6c473e3b468d005f7087576bdec5f68 387 Gene3D G3DSA:1.20.58.60 60 311 5.6E-4 T 28-03-2018 MKLM6_RS12005 457f245974ed3cf7568919df01d7cce0 661 Pfam PF00593 TonB dependent receptor 192 631 1.4E-25 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS12005 457f245974ed3cf7568919df01d7cce0 661 Pfam PF07715 TonB-dependent Receptor Plug Domain 50 158 1.4E-20 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS12005 457f245974ed3cf7568919df01d7cce0 661 Gene3D G3DSA:2.40.170.20 166 657 3.7E-49 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS12005 457f245974ed3cf7568919df01d7cce0 661 Gene3D G3DSA:2.170.130.10 26 165 1.1E-27 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS12005 457f245974ed3cf7568919df01d7cce0 661 SUPERFAMILY SSF56935 37 643 7.33E-89 T 28-03-2018 MKLM6_RS00595 f541abdc33e8eb39f8eafcad875d7dea 208 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 16 201 27.032 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MKLM6_RS00595 f541abdc33e8eb39f8eafcad875d7dea 208 Pfam PF02527 rRNA small subunit methyltransferase G 23 185 2.1E-51 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MKLM6_RS00595 f541abdc33e8eb39f8eafcad875d7dea 208 PIRSF PIRSF003078 1 207 4.1E-52 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MKLM6_RS00595 f541abdc33e8eb39f8eafcad875d7dea 208 Gene3D G3DSA:3.40.50.150 4 204 8.1E-28 T 28-03-2018 MKLM6_RS00595 f541abdc33e8eb39f8eafcad875d7dea 208 SUPERFAMILY SSF53335 6 205 8.28E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS00595 f541abdc33e8eb39f8eafcad875d7dea 208 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 28 199 3.9E-49 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MKLM6_RS04875 b05d33b02057a636114c550480962ee5 169 Gene3D G3DSA:1.10.10.10 73 163 2.1E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS04875 b05d33b02057a636114c550480962ee5 169 SUPERFAMILY SSF46767 79 153 3.27E-21 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MKLM6_RS04875 b05d33b02057a636114c550480962ee5 169 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 81 159 3.0E-22 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MKLM6_RS04875 b05d33b02057a636114c550480962ee5 169 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 82 161 2.8E-22 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MKLM6_RS04875 b05d33b02057a636114c550480962ee5 169 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 128 134 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MKLM6_RS08995 7d9731b1656121b6be5e6cde0d8ba3b8 279 Pfam PF01126 Heme oxygenase 76 260 1.4E-19 T 28-03-2018 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 MKLM6_RS08995 7d9731b1656121b6be5e6cde0d8ba3b8 279 Gene3D G3DSA:1.20.910.10 67 271 1.0E-31 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MKLM6_RS08995 7d9731b1656121b6be5e6cde0d8ba3b8 279 SUPERFAMILY SSF48613 74 264 1.04E-36 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MKLM6_RS11785 84b00ea6d8a410ad0389e1e8da8e9c21 273 Pfam PF04116 Fatty acid hydroxylase superfamily 93 228 1.7E-25 T 28-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 MKLM6_RS18275 2144d1e7eae807679dded895bcf19c3e 141 Pfam PF05901 Excalibur calcium-binding domain 104 136 1.7E-10 T 28-03-2018 IPR008613 Excalibur calcium-binding domain MKLM6_RS18275 2144d1e7eae807679dded895bcf19c3e 141 Pfam PF13511 Domain of unknown function (DUF4124) 8 61 3.6E-11 T 28-03-2018 IPR025392 Domain of unknown function DUF4124 MKLM6_RS17265 5bb4005d1b71565f9952d37008669a51 501 SUPERFAMILY SSF56762 13 465 1.19E-118 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS17265 5bb4005d1b71565f9952d37008669a51 501 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 456 465 - T 28-03-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 MKLM6_RS17265 5bb4005d1b71565f9952d37008669a51 501 Gene3D G3DSA:1.10.645.10 261 465 4.3E-39 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS17265 5bb4005d1b71565f9952d37008669a51 501 Gene3D G3DSA:1.10.645.10 11 260 1.8E-56 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MKLM6_RS17265 5bb4005d1b71565f9952d37008669a51 501 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 52 77 - T 28-03-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 MKLM6_RS17265 5bb4005d1b71565f9952d37008669a51 501 Pfam PF00374 Nickel-dependent hydrogenase 52 131 1.5E-15 T 28-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 MKLM6_RS17265 5bb4005d1b71565f9952d37008669a51 501 Pfam PF00374 Nickel-dependent hydrogenase 303 465 8.5E-15 T 28-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 MKLM6_RS03985 354a253df90fc1ec0446f80b742c53b3 563 Gene3D G3DSA:3.20.110.10 371 452 2.4E-19 T 28-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain MKLM6_RS03985 354a253df90fc1ec0446f80b742c53b3 563 Gene3D G3DSA:3.20.110.10 3 370 2.5E-73 T 28-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain MKLM6_RS03985 354a253df90fc1ec0446f80b742c53b3 563 Pfam PF03065 Glycosyl hydrolase family 57 10 465 8.0E-74 T 28-03-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 MKLM6_RS03985 354a253df90fc1ec0446f80b742c53b3 563 SUPERFAMILY SSF88713 191 452 1.71E-89 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MKLM6_RS03985 354a253df90fc1ec0446f80b742c53b3 563 SUPERFAMILY SSF88713 5 90 1.71E-89 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MKLM6_RS03985 354a253df90fc1ec0446f80b742c53b3 563 SUPERFAMILY SSF88713 146 164 1.71E-89 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MKLM6_RS12410 d333189c0847c9739ed84dd6bd5c5167 171 Pfam PF00293 NUDIX domain 30 153 2.3E-20 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MKLM6_RS12410 d333189c0847c9739ed84dd6bd5c5167 171 SUPERFAMILY SSF55811 4 165 2.3E-36 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MKLM6_RS12410 d333189c0847c9739ed84dd6bd5c5167 171 ProSitePatterns PS00893 Nudix box signature. 67 88 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MKLM6_RS12410 d333189c0847c9739ed84dd6bd5c5167 171 Gene3D G3DSA:3.90.79.10 1 169 1.4E-28 T 28-03-2018 MKLM6_RS08330 6c5967d9f3e1fff2a0eb42560135f14a 209 Gene3D G3DSA:3.40.430.10 2 209 1.1E-33 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 MKLM6_RS08330 6c5967d9f3e1fff2a0eb42560135f14a 209 Pfam PF01872 RibD C-terminal domain 3 183 7.4E-15 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MKLM6_RS08330 6c5967d9f3e1fff2a0eb42560135f14a 209 SUPERFAMILY SSF53597 64 208 6.81E-21 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 MKLM6_RS04115 f0cad89b38071fd78d3a1e7e3b6724f6 164 Gene3D G3DSA:3.40.30.10 14 164 3.1E-38 T 28-03-2018 MKLM6_RS04115 f0cad89b38071fd78d3a1e7e3b6724f6 164 SUPERFAMILY SSF52833 20 163 6.91E-39 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS04115 f0cad89b38071fd78d3a1e7e3b6724f6 164 ProSitePatterns PS00194 Thioredoxin family active site. 53 71 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MKLM6_RS04115 f0cad89b38071fd78d3a1e7e3b6724f6 164 Pfam PF08534 Redoxin 25 155 4.4E-27 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 MKLM6_RS00335 b71aa90cc5fc179cbde45bd8e9f3cf10 90 SUPERFAMILY SSF160191 1 78 9.81E-30 T 28-03-2018 MKLM6_RS00335 b71aa90cc5fc179cbde45bd8e9f3cf10 90 Pfam PF05166 YcgL domain 3 75 1.4E-31 T 28-03-2018 IPR027354 YcgL domain MKLM6_RS00335 b71aa90cc5fc179cbde45bd8e9f3cf10 90 Hamap MF_01866 Protein YcgL [ycgL]. 1 85 22.961 T 28-03-2018 IPR027354 YcgL domain MKLM6_RS00335 b71aa90cc5fc179cbde45bd8e9f3cf10 90 ProDom PD030374 YCGL UNCHARACTERIZED SIMILAR BACTERIA HI1446 Y2231 HYDROLASE CYTOPLASMIC YPO2080 SO2575 24 73 2.0E-8 T 28-03-2018 IPR027354 YcgL domain MKLM6_RS15190 8ca5652848060e46f373382288c298ca 249 SUPERFAMILY SSF56300 4 211 2.19E-28 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS15190 8ca5652848060e46f373382288c298ca 249 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 5 225 5.8E-81 T 28-03-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 MKLM6_RS15190 8ca5652848060e46f373382288c298ca 249 Gene3D G3DSA:3.60.21.10 1 224 1.3E-23 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS15190 8ca5652848060e46f373382288c298ca 249 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 243 92.917 T 28-03-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 MKLM6_RS15190 8ca5652848060e46f373382288c298ca 249 Pfam PF00149 Calcineurin-like phosphoesterase 4 200 4.4E-8 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MKLM6_RS15455 48558ea65777a1772a9532b0fd2f2705 296 Pfam PF00294 pfkB family carbohydrate kinase 21 279 2.1E-45 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB MKLM6_RS15455 48558ea65777a1772a9532b0fd2f2705 296 SUPERFAMILY SSF53613 5 281 4.21E-56 T 28-03-2018 IPR029056 Ribokinase-like MKLM6_RS15455 48558ea65777a1772a9532b0fd2f2705 296 Gene3D G3DSA:3.40.1190.20 5 292 2.0E-50 T 28-03-2018 IPR029056 Ribokinase-like MKLM6_RS16135 ff231a00fdfc61802f3fa27386b4de9c 326 TIGRFAM TIGR01933 hflK: HflK protein 36 312 3.2E-81 T 28-03-2018 IPR010201 HflK GO:0016021 MKLM6_RS16135 ff231a00fdfc61802f3fa27386b4de9c 326 SUPERFAMILY SSF117892 108 221 1.83E-23 T 28-03-2018 IPR001107 Band 7 domain MKLM6_RS16135 ff231a00fdfc61802f3fa27386b4de9c 326 Pfam PF01145 SPFH domain / Band 7 family 38 230 7.0E-25 T 28-03-2018 IPR001107 Band 7 domain MKLM6_RS16135 ff231a00fdfc61802f3fa27386b4de9c 326 SMART SM00244 34 214 3.1E-23 T 28-03-2018 IPR001107 Band 7 domain MKLM6_RS16370 a48fe6741994633938e526c79f16fdd1 162 Gene3D G3DSA:3.10.450.160 28 162 2.6E-18 T 28-03-2018 MKLM6_RS07490 8bd516a52e0235c14210dc01720da03c 245 Pfam PF01863 Protein of unknown function DUF45 27 238 3.0E-59 T 28-03-2018 IPR002725 Protein of unknown function DUF45 MKLM6_RS01540 3651c80c40b28a29f75185dfcd672a20 265 SUPERFAMILY SSF51366 15 264 1.18E-91 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MKLM6_RS01540 3651c80c40b28a29f75185dfcd672a20 265 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 6 265 35.956 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 MKLM6_RS01540 3651c80c40b28a29f75185dfcd672a20 265 Pfam PF00218 Indole-3-glycerol phosphate synthase 8 263 3.4E-97 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 MKLM6_RS01540 3651c80c40b28a29f75185dfcd672a20 265 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 59 77 - T 28-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 MKLM6_RS01540 3651c80c40b28a29f75185dfcd672a20 265 Gene3D G3DSA:3.20.20.70 14 264 2.4E-74 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS17210 791b1109b830fd310240c3b0c1ae406c 250 PIRSF PIRSF009120 1 248 4.0E-92 T 28-03-2018 IPR016545 Uncharacterised conserved protein UCP009120, proteasome-type protease, Sll0069 MKLM6_RS17210 791b1109b830fd310240c3b0c1ae406c 250 SUPERFAMILY SSF56235 2 238 3.66E-33 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MKLM6_RS17210 791b1109b830fd310240c3b0c1ae406c 250 Gene3D G3DSA:3.60.20.10 1 208 3.1E-35 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MKLM6_RS07675 f0072b5a8dd0b8d7d7b75c777060e3dd 138 Gene3D G3DSA:1.20.120.330 3 131 0.0016 T 28-03-2018 MKLM6_RS11285 ffa650a9a2cb012ddc7228488ae9f94c 416 Gene3D G3DSA:3.20.20.370 111 356 6.3E-6 T 28-03-2018 MKLM6_RS05260 27560da7d0d135836d9ad2a4c8adb5d1 271 SUPERFAMILY SSF52096 48 158 7.46E-28 T 28-03-2018 IPR029045 ClpP/crotonase-like domain MKLM6_RS05260 27560da7d0d135836d9ad2a4c8adb5d1 271 SUPERFAMILY SSF52096 187 247 7.46E-28 T 28-03-2018 IPR029045 ClpP/crotonase-like domain MKLM6_RS05260 27560da7d0d135836d9ad2a4c8adb5d1 271 Pfam PF01343 Peptidase family S49 112 254 1.4E-29 T 28-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 MKLM6_RS05260 27560da7d0d135836d9ad2a4c8adb5d1 271 Gene3D G3DSA:3.90.226.10 65 263 5.9E-22 T 28-03-2018 MKLM6_RS14280 2815a3f58c3f2801b0637bc6629981ab 371 Pfam PF01757 Acyltransferase family 8 352 1.8E-23 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 MKLM6_RS06295 452ec351997dd29d2ac533ff9cf4a1ff 279 Pfam PF01063 Amino-transferase class IV 24 246 5.0E-48 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 MKLM6_RS06295 452ec351997dd29d2ac533ff9cf4a1ff 279 Gene3D G3DSA:3.20.10.10 112 270 3.6E-40 T 28-03-2018 MKLM6_RS06295 452ec351997dd29d2ac533ff9cf4a1ff 279 Gene3D G3DSA:3.30.470.10 5 111 4.3E-24 T 28-03-2018 MKLM6_RS06295 452ec351997dd29d2ac533ff9cf4a1ff 279 SUPERFAMILY SSF56752 2 262 4.84E-73 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 MKLM6_RS06295 452ec351997dd29d2ac533ff9cf4a1ff 279 TIGRFAM TIGR03461 pabC_Proteo: aminodeoxychorismate lyase 4 263 2.8E-91 T 28-03-2018 IPR017824 Aminodeoxychorismate lyase, class IV GO:0008696|GO:0030170|GO:0046656 KEGG: 00790+4.1.3.38|MetaCyc: PWY-6543 MKLM6_RS21805 ebba91d7f39938f95da7040031814105 431 SUPERFAMILY SSF52402 4 206 3.2E-21 T 28-03-2018 MKLM6_RS21805 ebba91d7f39938f95da7040031814105 431 TIGRFAM TIGR03183 DNA_S_dndC: putative sulfurtransferase DndC 7 417 7.5E-117 T 28-03-2018 IPR017598 Sulphur transferase DndC, putative MKLM6_RS21805 ebba91d7f39938f95da7040031814105 431 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 21 247 1.4E-8 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 MKLM6_RS21805 ebba91d7f39938f95da7040031814105 431 Gene3D G3DSA:3.40.50.620 2 258 1.8E-32 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS01150 d0b50436aa556eb6837087d7f6af5636 319 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 218 2.6E-33 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MKLM6_RS01150 d0b50436aa556eb6837087d7f6af5636 319 Gene3D G3DSA:3.40.50.720 2 317 7.5E-57 T 28-03-2018 MKLM6_RS01150 d0b50436aa556eb6837087d7f6af5636 319 SUPERFAMILY SSF51735 5 315 1.28E-66 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS14145 efdfc5326986fe67681f5a2730dba8f3 402 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MKLM6_RS14145 efdfc5326986fe67681f5a2730dba8f3 402 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 25 36 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MKLM6_RS14145 efdfc5326986fe67681f5a2730dba8f3 402 Pfam PF12838 4Fe-4S dicluster domain 24 89 2.0E-13 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MKLM6_RS14145 efdfc5326986fe67681f5a2730dba8f3 402 Gene3D G3DSA:3.30.70.20 5 34 0.0044 T 28-03-2018 MKLM6_RS14145 efdfc5326986fe67681f5a2730dba8f3 402 Gene3D G3DSA:3.30.70.20 35 76 2.5E-9 T 28-03-2018 MKLM6_RS14145 efdfc5326986fe67681f5a2730dba8f3 402 Gene3D G3DSA:3.30.70.20 77 304 1.5E-5 T 28-03-2018 MKLM6_RS14145 efdfc5326986fe67681f5a2730dba8f3 402 Pfam PF02754 Cysteine-rich domain 299 383 8.7E-9 T 28-03-2018 IPR004017 Cysteine-rich domain MKLM6_RS14145 efdfc5326986fe67681f5a2730dba8f3 402 Pfam PF02754 Cysteine-rich domain 171 253 9.2E-10 T 28-03-2018 IPR004017 Cysteine-rich domain MKLM6_RS14145 efdfc5326986fe67681f5a2730dba8f3 402 SUPERFAMILY SSF54862 22 124 5.02E-21 T 28-03-2018 MKLM6_RS14145 efdfc5326986fe67681f5a2730dba8f3 402 PIRSF PIRSF000139 7 400 3.0E-111 T 28-03-2018 MKLM6_RS04520 54235db600deb6b7eee1aba5691e52ba 350 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 25 180 9.1E-42 T 28-03-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS04520 54235db600deb6b7eee1aba5691e52ba 350 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 192 342 3.8E-24 T 28-03-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS04520 54235db600deb6b7eee1aba5691e52ba 350 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 13 347 27.649 T 28-03-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS04520 54235db600deb6b7eee1aba5691e52ba 350 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 85 98 - T 28-03-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 MKLM6_RS04520 54235db600deb6b7eee1aba5691e52ba 350 Gene3D G3DSA:3.30.2340.10 176 308 4.1E-26 T 28-03-2018 MKLM6_RS04520 54235db600deb6b7eee1aba5691e52ba 350 SUPERFAMILY SSF55120 15 344 3.31E-88 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MKLM6_RS11250 47e6891a9a77c6d8b165613b2d5a3b89 347 Pfam PF00535 Glycosyl transferase family 2 27 187 3.8E-18 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MKLM6_RS11250 47e6891a9a77c6d8b165613b2d5a3b89 347 SUPERFAMILY SSF53448 15 305 3.48E-52 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS11250 47e6891a9a77c6d8b165613b2d5a3b89 347 Gene3D G3DSA:3.90.550.10 11 321 4.9E-42 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS03745 f7ac444274332e26566b2bc954bd2aac 187 SMART SM00347 23 123 5.2E-4 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MKLM6_RS03745 f7ac444274332e26566b2bc954bd2aac 187 Gene3D G3DSA:1.10.10.10 1 143 4.0E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS03745 f7ac444274332e26566b2bc954bd2aac 187 Pfam PF12802 MarR family 28 88 1.2E-8 T 28-03-2018 MKLM6_RS03745 f7ac444274332e26566b2bc954bd2aac 187 SUPERFAMILY SSF46785 6 108 1.13E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS19930 b5c2533e8e18f6a49498be1e32a1158e 337 SMART SM00116 223 271 0.69 T 28-03-2018 IPR000644 CBS domain MKLM6_RS19930 b5c2533e8e18f6a49498be1e32a1158e 337 SMART SM00116 288 336 0.16 T 28-03-2018 IPR000644 CBS domain MKLM6_RS19930 b5c2533e8e18f6a49498be1e32a1158e 337 Pfam PF01380 SIS domain 53 184 1.8E-30 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MKLM6_RS19930 b5c2533e8e18f6a49498be1e32a1158e 337 Pfam PF00571 CBS domain 214 270 5.9E-5 T 28-03-2018 IPR000644 CBS domain MKLM6_RS19930 b5c2533e8e18f6a49498be1e32a1158e 337 Pfam PF00571 CBS domain 281 334 4.0E-8 T 28-03-2018 IPR000644 CBS domain MKLM6_RS19930 b5c2533e8e18f6a49498be1e32a1158e 337 SUPERFAMILY SSF53697 19 334 2.67E-67 T 28-03-2018 MKLM6_RS19930 b5c2533e8e18f6a49498be1e32a1158e 337 PIRSF PIRSF004692 7 337 3.3E-130 T 28-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 MKLM6_RS19930 b5c2533e8e18f6a49498be1e32a1158e 337 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 58 327 9.9E-106 T 28-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 MKLM6_RS19930 b5c2533e8e18f6a49498be1e32a1158e 337 Gene3D G3DSA:3.10.580.10 211 337 4.5E-22 T 28-03-2018 MKLM6_RS19930 b5c2533e8e18f6a49498be1e32a1158e 337 Gene3D G3DSA:3.40.50.10490 15 210 1.0E-57 T 28-03-2018 MKLM6_RS00950 36002ab023443f7ccfc1bae650d3286e 71 SUPERFAMILY SSF57716 6 62 3.14E-19 T 28-03-2018 MKLM6_RS00950 36002ab023443f7ccfc1bae650d3286e 71 Gene3D G3DSA:3.30.50.10 4 67 1.8E-21 T 28-03-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 MKLM6_RS00950 36002ab023443f7ccfc1bae650d3286e 71 Hamap MF_00649 DNA gyrase inhibitor YacG [yacG]. 5 68 17.86 T 28-03-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 MKLM6_RS00950 36002ab023443f7ccfc1bae650d3286e 71 Pfam PF03884 DNA gyrase inhibitor YacG 9 57 1.2E-21 T 28-03-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 MKLM6_RS17895 2787090f757cfabc039a323a7d64c505 174 Pfam PF09684 Phage tail protein (Tail_P2_I) 23 133 3.4E-5 T 28-03-2018 IPR006521 Tail protein I MKLM6_RS21095 b4754be5178e1031a081529991aff800 355 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 4 353 1.8E-105 T 28-03-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 MKLM6_RS21095 b4754be5178e1031a081529991aff800 355 Pfam PF03739 Predicted permease YjgP/YjgQ family 7 351 8.0E-62 T 28-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 MKLM6_RS10710 2b729ffc5a9ff819ff223000df597eec 364 PIRSF PIRSF038945 1 362 2.9E-157 T 28-03-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 MKLM6_RS10710 2b729ffc5a9ff819ff223000df597eec 364 Gene3D G3DSA:3.40.50.1100 44 150 2.2E-25 T 28-03-2018 MKLM6_RS10710 2b729ffc5a9ff819ff223000df597eec 364 TIGRFAM TIGR00260 thrC: threonine synthase 11 335 4.3E-92 T 28-03-2018 IPR004450 Threonine synthase-like MKLM6_RS10710 2b729ffc5a9ff819ff223000df597eec 364 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 28 328 2.1E-66 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MKLM6_RS10710 2b729ffc5a9ff819ff223000df597eec 364 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 57 70 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 MKLM6_RS10710 2b729ffc5a9ff819ff223000df597eec 364 Gene3D G3DSA:3.40.50.1100 151 345 1.0E-51 T 28-03-2018 MKLM6_RS10710 2b729ffc5a9ff819ff223000df597eec 364 SUPERFAMILY SSF53686 8 362 1.83E-105 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MKLM6_RS22265 f124463d7cebc8b5793cbef63a430a0c 78 Pfam PF05406 WGR domain 4 75 7.9E-19 T 28-03-2018 IPR008893 WGR domain MKLM6_RS22265 f124463d7cebc8b5793cbef63a430a0c 78 SUPERFAMILY SSF142921 4 75 2.88E-18 T 28-03-2018 IPR008893 WGR domain MKLM6_RS22265 f124463d7cebc8b5793cbef63a430a0c 78 Gene3D G3DSA:2.20.140.10 6 77 9.8E-12 T 28-03-2018 IPR008893 WGR domain MKLM6_RS22265 f124463d7cebc8b5793cbef63a430a0c 78 SMART SM00773 2 77 4.9E-13 T 28-03-2018 IPR008893 WGR domain MKLM6_RS07510 8106c9e3416862fddf82a09a50f5af79 164 Gene3D G3DSA:3.40.960.10 25 120 2.7E-26 T 28-03-2018 MKLM6_RS07510 8106c9e3416862fddf82a09a50f5af79 164 Pfam PF04480 Protein of unknown function (DUF559) 19 118 5.5E-32 T 28-03-2018 IPR007569 Domain of unknown function DUF559 MKLM6_RS07510 8106c9e3416862fddf82a09a50f5af79 164 SUPERFAMILY SSF52980 9 118 3.91E-17 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MKLM6_RS09700 2aed0b9ea33e40f27287dbb241fbcbaf 202 Gene3D G3DSA:1.20.120.20 23 193 2.7E-7 T 28-03-2018 MKLM6_RS09700 2aed0b9ea33e40f27287dbb241fbcbaf 202 Pfam PF04972 BON domain 128 195 2.9E-13 T 28-03-2018 IPR007055 BON domain MKLM6_RS09700 2aed0b9ea33e40f27287dbb241fbcbaf 202 SMART SM00749 133 196 4.6E-6 T 28-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria MKLM6_RS12620 861edfb139876220c6c3ea6480d8b3a9 192 Gene3D G3DSA:2.40.10.220 104 192 4.1E-6 T 28-03-2018 MKLM6_RS12620 861edfb139876220c6c3ea6480d8b3a9 192 Gene3D G3DSA:2.40.10.220 1 103 4.3E-8 T 28-03-2018 MKLM6_RS12620 861edfb139876220c6c3ea6480d8b3a9 192 Pfam PF07238 PilZ domain 107 190 1.3E-5 T 28-03-2018 IPR009875 PilZ domain GO:0035438 MKLM6_RS12620 861edfb139876220c6c3ea6480d8b3a9 192 Pfam PF07238 PilZ domain 3 97 6.0E-7 T 28-03-2018 IPR009875 PilZ domain GO:0035438 MKLM6_RS12620 861edfb139876220c6c3ea6480d8b3a9 192 SUPERFAMILY SSF141371 5 43 4.32E-6 T 28-03-2018 MKLM6_RS07690 a8eadd059363a6785f55c7e7a9e98af3 196 Gene3D G3DSA:3.90.1570.10 1 188 3.6E-46 T 28-03-2018 MKLM6_RS07690 a8eadd059363a6785f55c7e7a9e98af3 196 SUPERFAMILY SSF52980 9 187 2.84E-39 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MKLM6_RS07690 a8eadd059363a6785f55c7e7a9e98af3 196 Pfam PF05685 Putative restriction endonuclease 15 175 1.1E-36 T 28-03-2018 IPR008538 Domain of unknown function DUF820 MKLM6_RS21575 b532266d939c1cff986785d3972af159 239 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 12 223 1.6E-70 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 MKLM6_RS21575 b532266d939c1cff986785d3972af159 239 SUPERFAMILY SSF109755 12 233 1.67E-71 T 28-03-2018 MKLM6_RS21575 b532266d939c1cff986785d3972af159 239 Gene3D G3DSA:1.20.58.220 6 121 4.3E-28 T 28-03-2018 MKLM6_RS21575 b532266d939c1cff986785d3972af159 239 PIRSF PIRSF003107 7 227 1.1E-70 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 MKLM6_RS21575 b532266d939c1cff986785d3972af159 239 Gene3D G3DSA:1.20.58.220 126 238 7.2E-30 T 28-03-2018 MKLM6_RS21575 b532266d939c1cff986785d3972af159 239 Pfam PF01895 PhoU domain 130 213 1.1E-18 T 28-03-2018 IPR026022 PhoU domain MKLM6_RS21575 b532266d939c1cff986785d3972af159 239 Pfam PF01895 PhoU domain 26 112 7.5E-23 T 28-03-2018 IPR026022 PhoU domain MKLM6_RS01965 6fa5f0a4123d292c72e8468c5cb6ef0a 231 SUPERFAMILY SSF48452 61 179 7.49E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS01965 6fa5f0a4123d292c72e8468c5cb6ef0a 231 Gene3D G3DSA:1.25.40.10 27 144 6.7E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS01965 6fa5f0a4123d292c72e8468c5cb6ef0a 231 Gene3D G3DSA:1.25.40.10 145 219 3.0E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS19645 66186ce8928903ab41e590965919b85a 489 Gene3D G3DSA:1.10.287.950 183 355 2.5E-40 T 28-03-2018 MKLM6_RS19645 66186ce8928903ab41e590965919b85a 489 SMART SM00283 150 380 3.2E-15 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS19645 66186ce8928903ab41e590965919b85a 489 Pfam PF13682 Chemoreceptor zinc-binding domain 374 442 1.5E-8 T 28-03-2018 IPR025991 Chemoreceptor zinc-binding domain MKLM6_RS19645 66186ce8928903ab41e590965919b85a 489 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 196 352 1.9E-31 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS19645 66186ce8928903ab41e590965919b85a 489 SUPERFAMILY SSF58104 93 116 1.44E-45 T 28-03-2018 MKLM6_RS19645 66186ce8928903ab41e590965919b85a 489 SUPERFAMILY SSF58104 174 360 1.44E-45 T 28-03-2018 MKLM6_RS10065 800c2229e85e5403a5373c8eea7c05f5 95 SUPERFAMILY SSF109910 4 75 1.44E-17 T 28-03-2018 IPR005631 Flavinator of succinate dehydrogenase MKLM6_RS10065 800c2229e85e5403a5373c8eea7c05f5 95 Gene3D G3DSA:1.10.150.250 1 80 2.6E-19 T 28-03-2018 MKLM6_RS10065 800c2229e85e5403a5373c8eea7c05f5 95 Pfam PF03937 Flavinator of succinate dehydrogenase 5 71 3.9E-19 T 28-03-2018 IPR005631 Flavinator of succinate dehydrogenase MKLM6_RS21735 9c61a921b1de99b8f8f3edf6cd475ec2 363 Gene3D G3DSA:3.40.50.300 237 320 2.9E-8 T 28-03-2018 MKLM6_RS21735 9c61a921b1de99b8f8f3edf6cd475ec2 363 Pfam PF13175 AAA ATPase domain 231 295 3.1E-11 T 28-03-2018 MKLM6_RS21735 9c61a921b1de99b8f8f3edf6cd475ec2 363 PIRSF PIRSF034888 1 361 4.8E-49 T 28-03-2018 IPR014592 Predicted P-loop ATP-binding protein, VCA0200 MKLM6_RS21735 9c61a921b1de99b8f8f3edf6cd475ec2 363 Gene3D G3DSA:3.40.50.300 1 224 8.8E-9 T 28-03-2018 MKLM6_RS21735 9c61a921b1de99b8f8f3edf6cd475ec2 363 Pfam PF12476 Protein of unknown function (DUF3696) 310 355 5.7E-7 T 28-03-2018 IPR022532 Domain of unknown function DUF3696, C-terminal MKLM6_RS21735 9c61a921b1de99b8f8f3edf6cd475ec2 363 SUPERFAMILY SSF52540 166 296 1.2E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS21735 9c61a921b1de99b8f8f3edf6cd475ec2 363 SUPERFAMILY SSF52540 5 49 1.2E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS21630 a50eb76f192d417e927729d56584eacd 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 89 107 8.0E-45 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MKLM6_RS21630 a50eb76f192d417e927729d56584eacd 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 107 133 8.0E-45 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MKLM6_RS21630 a50eb76f192d417e927729d56584eacd 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 158 186 8.0E-45 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MKLM6_RS21630 a50eb76f192d417e927729d56584eacd 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 12 39 8.0E-45 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MKLM6_RS21630 a50eb76f192d417e927729d56584eacd 251 Pfam PF00902 Sec-independent protein translocase protein (TatC) 16 225 3.0E-64 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MKLM6_RS21630 a50eb76f192d417e927729d56584eacd 251 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 14 230 2.7E-68 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MKLM6_RS21630 a50eb76f192d417e927729d56584eacd 251 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 7 244 17.887 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MKLM6_RS06545 57bd8615717fab3d4246481b52857f4d 391 Gene3D G3DSA:3.40.50.2000 178 377 5.1E-44 T 28-03-2018 MKLM6_RS06545 57bd8615717fab3d4246481b52857f4d 391 TIGRFAM TIGR04047 MSMEG_0565_glyc: glycosyltransferase, MSMEG_0565 family 5 380 1.0E-144 T 28-03-2018 IPR023986 Glycosyltransferase, putative, MSMEG0565 family MKLM6_RS06545 57bd8615717fab3d4246481b52857f4d 391 Pfam PF00534 Glycosyl transferases group 1 198 349 9.5E-25 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 MKLM6_RS06545 57bd8615717fab3d4246481b52857f4d 391 Pfam PF13439 Glycosyltransferase Family 4 17 176 1.8E-18 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MKLM6_RS06545 57bd8615717fab3d4246481b52857f4d 391 SUPERFAMILY SSF53756 4 384 5.07E-67 T 28-03-2018 MKLM6_RS06545 57bd8615717fab3d4246481b52857f4d 391 Gene3D G3DSA:3.40.50.2000 1 177 2.9E-12 T 28-03-2018 MKLM6_RS07785 763b635200588f4bdd79fa7b70c89307 319 SUPERFAMILY SSF50129 12 167 9.11E-35 T 28-03-2018 IPR011032 GroES-like MKLM6_RS07785 763b635200588f4bdd79fa7b70c89307 319 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 128 3.8E-21 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MKLM6_RS07785 763b635200588f4bdd79fa7b70c89307 319 Gene3D G3DSA:3.40.50.720 155 270 8.5E-13 T 28-03-2018 MKLM6_RS07785 763b635200588f4bdd79fa7b70c89307 319 SUPERFAMILY SSF51735 134 278 6.07E-15 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS07785 763b635200588f4bdd79fa7b70c89307 319 Gene3D G3DSA:3.90.180.10 1 154 2.1E-31 T 28-03-2018 MKLM6_RS04130 aab858feef4fcc3301b7edd8ccfb4ccb 182 SMART SM00448 9 120 8.3E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS04130 aab858feef4fcc3301b7edd8ccfb4ccb 182 Pfam PF02954 Bacterial regulatory protein, Fis family 139 177 3.9E-11 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS04130 aab858feef4fcc3301b7edd8ccfb4ccb 182 Gene3D G3DSA:1.10.10.60 131 176 4.0E-15 T 28-03-2018 MKLM6_RS04130 aab858feef4fcc3301b7edd8ccfb4ccb 182 SUPERFAMILY SSF52172 7 125 1.71E-28 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS04130 aab858feef4fcc3301b7edd8ccfb4ccb 182 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 161 181 1.6E-6 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS04130 aab858feef4fcc3301b7edd8ccfb4ccb 182 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 144 161 1.6E-6 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS04130 aab858feef4fcc3301b7edd8ccfb4ccb 182 SUPERFAMILY SSF46689 111 177 2.42E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS04130 aab858feef4fcc3301b7edd8ccfb4ccb 182 Pfam PF00072 Response regulator receiver domain 12 120 2.0E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS04130 aab858feef4fcc3301b7edd8ccfb4ccb 182 Gene3D G3DSA:3.40.50.2300 2 123 1.5E-24 T 28-03-2018 MKLM6_RS00180 ebebce012a5b21ae945f5bab093f4c0b 312 SUPERFAMILY SSF56349 21 289 1.27E-48 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS00180 ebebce012a5b21ae945f5bab093f4c0b 312 Gene3D G3DSA:1.10.443.10 128 297 1.4E-34 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS00180 ebebce012a5b21ae945f5bab093f4c0b 312 Pfam PF00589 Phage integrase family 130 285 1.5E-23 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS00180 ebebce012a5b21ae945f5bab093f4c0b 312 Gene3D G3DSA:1.10.150.130 15 127 3.3E-9 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal MKLM6_RS12860 de3d97f638e1c8b886f063dbfe946af1 72 Pfam PF07862 Nif11 domain 1 45 2.9E-11 T 28-03-2018 IPR012903 Nif11 domain MKLM6_RS12860 de3d97f638e1c8b886f063dbfe946af1 72 TIGRFAM TIGR03798 ocin_TIGR03798: nif11-like leader peptide domain 1 49 1.6E-9 T 28-03-2018 IPR022516 Nif11-like leader peptide MKLM6_RS14225 c718692e8c60b0552e590b91fa09cdf8 390 Gene3D G3DSA:1.20.91.10 231 317 4.0E-17 T 28-03-2018 MKLM6_RS14225 c718692e8c60b0552e590b91fa09cdf8 390 Pfam PF00999 Sodium/hydrogen exchanger family 9 384 2.5E-40 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MKLM6_RS19310 7e21c7ee526e5e6222c1d5d1c14fce17 276 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 57 266 9.0E-93 T 28-03-2018 IPR004392 Hydrogenase accessory protein HypB GO:0006461|GO:0016151 MKLM6_RS19310 7e21c7ee526e5e6222c1d5d1c14fce17 276 SUPERFAMILY SSF52540 60 266 2.26E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS19310 7e21c7ee526e5e6222c1d5d1c14fce17 276 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 86 248 1.1E-37 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain MKLM6_RS19310 7e21c7ee526e5e6222c1d5d1c14fce17 276 PIRSF PIRSF005624 50 272 5.0E-99 T 28-03-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 MKLM6_RS19310 7e21c7ee526e5e6222c1d5d1c14fce17 276 Gene3D G3DSA:3.40.50.300 85 246 5.8E-22 T 28-03-2018 MKLM6_RS05815 768db859780580569dd397fe02b3fc2e 222 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 18 215 3.0E-41 T 28-03-2018 IPR006214 Bax inhibitor 1-related MKLM6_RS14325 a32c5df86358262228121e8f4ea59298 136 Gene3D G3DSA:3.40.50.720 3 124 3.0E-13 T 28-03-2018 MKLM6_RS14325 a32c5df86358262228121e8f4ea59298 136 SUPERFAMILY SSF51735 10 111 4.21E-15 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS14325 a32c5df86358262228121e8f4ea59298 136 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 25 102 2.5E-6 T 28-03-2018 MKLM6_RS18285 b14d21bd5ff94d6c885ce13c0e73cd81 125 Gene3D G3DSA:1.10.3290.10 29 125 1.3E-10 T 28-03-2018 IPR003812 Fido domain MKLM6_RS18285 b14d21bd5ff94d6c885ce13c0e73cd81 125 TIGRFAM TIGR01550 DOC_P1: death-on-curing family protein 13 121 3.7E-16 T 28-03-2018 IPR006440 Death on curing protein GO:0016301 MKLM6_RS18285 b14d21bd5ff94d6c885ce13c0e73cd81 125 Pfam PF02661 Fic/DOC family 7 85 8.3E-12 T 28-03-2018 IPR003812 Fido domain MKLM6_RS18285 b14d21bd5ff94d6c885ce13c0e73cd81 125 SUPERFAMILY SSF140931 13 92 5.36E-9 T 28-03-2018 IPR003812 Fido domain MKLM6_RS18285 b14d21bd5ff94d6c885ce13c0e73cd81 125 PIRSF PIRSF018297 3 125 8.5E-38 T 28-03-2018 IPR006440 Death on curing protein GO:0016301 MKLM6_RS04550 4e7a058373d5dba475fa77b7dae91f0b 240 Gene3D G3DSA:3.80.10.10 10 110 1.3E-8 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like MKLM6_RS04550 4e7a058373d5dba475fa77b7dae91f0b 240 SUPERFAMILY SSF52058 19 167 2.83E-14 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like MKLM6_RS04550 4e7a058373d5dba475fa77b7dae91f0b 240 Gene3D G3DSA:3.80.10.10 111 199 4.5E-7 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like MKLM6_RS15050 1a24a92f53d2dae08019ea0fb531075d 265 PIRSF PIRSF006241 1 260 9.1E-86 T 28-03-2018 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 MKLM6_RS15050 1a24a92f53d2dae08019ea0fb531075d 265 Pfam PF01261 Xylose isomerase-like TIM barrel 21 215 1.0E-29 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MKLM6_RS15050 1a24a92f53d2dae08019ea0fb531075d 265 Gene3D G3DSA:3.20.20.150 1 260 7.4E-55 T 28-03-2018 MKLM6_RS15050 1a24a92f53d2dae08019ea0fb531075d 265 SUPERFAMILY SSF51658 1 257 1.8E-70 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MKLM6_RS05160 0cb99666314fb4c77632eccadb0d1eb4 228 Gene3D G3DSA:1.10.10.10 123 228 2.3E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS05160 0cb99666314fb4c77632eccadb0d1eb4 228 SUPERFAMILY SSF46894 127 226 2.41E-24 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MKLM6_RS05160 0cb99666314fb4c77632eccadb0d1eb4 228 SMART SM00448 2 112 2.3E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS05160 0cb99666314fb4c77632eccadb0d1eb4 228 Pfam PF00072 Response regulator receiver domain 4 113 4.9E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS05160 0cb99666314fb4c77632eccadb0d1eb4 228 SMART SM00862 149 225 3.7E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS05160 0cb99666314fb4c77632eccadb0d1eb4 228 Gene3D G3DSA:3.40.50.2300 1 122 1.1E-32 T 28-03-2018 MKLM6_RS05160 0cb99666314fb4c77632eccadb0d1eb4 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 225 4.4E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS05160 0cb99666314fb4c77632eccadb0d1eb4 228 SUPERFAMILY SSF52172 2 127 1.12E-36 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS04440 09674bad4712d364239a7b854cca5671 175 SUPERFAMILY SSF101327 2 162 3.27E-30 T 28-03-2018 IPR011978 Uncharacterised protein family UPF0149 MKLM6_RS04440 09674bad4712d364239a7b854cca5671 175 Pfam PF03695 Uncharacterised protein family (UPF0149) 6 167 1.9E-27 T 28-03-2018 IPR011978 Uncharacterised protein family UPF0149 MKLM6_RS15860 8d37ec5f0c1564039218c8b0c4ae533c 332 TIGRFAM TIGR03589 PseB: UDP-N-acetylglucosamine 4,6-dehydratase (inverting) 1 321 4.4E-160 T 28-03-2018 IPR020025 UDP-N-acetylglucosamine 4,6-dehydratase (inverting) KEGG: 00010+4.2.1.11|KEGG: 00520+4.2.1.115|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6143|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|MetaCyc: PWY-7330|MetaCyc: PWY-7331|MetaCyc: PWY-7332|MetaCyc: PWY-7719 MKLM6_RS15860 8d37ec5f0c1564039218c8b0c4ae533c 332 Gene3D G3DSA:3.40.50.720 1 328 1.0E-59 T 28-03-2018 MKLM6_RS15860 8d37ec5f0c1564039218c8b0c4ae533c 332 SUPERFAMILY SSF51735 1 261 7.42E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS15860 8d37ec5f0c1564039218c8b0c4ae533c 332 Pfam PF02719 Polysaccharide biosynthesis protein 7 278 1.1E-96 T 28-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain MKLM6_RS11845 94228db56f349215e75d9f5b3b134a0d 160 Gene3D G3DSA:3.40.630.30 7 154 3.5E-24 T 28-03-2018 MKLM6_RS11845 94228db56f349215e75d9f5b3b134a0d 160 SUPERFAMILY SSF55729 8 139 7.09E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS11845 94228db56f349215e75d9f5b3b134a0d 160 Pfam PF13508 Acetyltransferase (GNAT) domain 52 133 3.6E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 MKLM6_RS19955 28520eba0db73af15f6e193f9eeb9d86 421 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 409 3.1E-113 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MKLM6_RS19955 28520eba0db73af15f6e193f9eeb9d86 421 Gene3D G3DSA:3.65.10.10 222 421 1.6E-44 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MKLM6_RS19955 28520eba0db73af15f6e193f9eeb9d86 421 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 419 44.34 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS19955 28520eba0db73af15f6e193f9eeb9d86 421 Gene3D G3DSA:3.65.10.10 21 221 3.3E-46 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MKLM6_RS19955 28520eba0db73af15f6e193f9eeb9d86 421 SUPERFAMILY SSF55205 1 420 1.96E-138 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 MKLM6_RS19955 28520eba0db73af15f6e193f9eeb9d86 421 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 418 1.7E-179 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MKLM6_RS02345 92ec8cccac20759b1e4076151cdd32a7 299 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 164 176 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MKLM6_RS02345 92ec8cccac20759b1e4076151cdd32a7 299 Gene3D G3DSA:1.10.510.10 111 299 2.8E-30 T 28-03-2018 MKLM6_RS02345 92ec8cccac20759b1e4076151cdd32a7 299 Pfam PF00069 Protein kinase domain 26 248 9.2E-32 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MKLM6_RS02345 92ec8cccac20759b1e4076151cdd32a7 299 Gene3D G3DSA:3.30.200.20 15 110 1.6E-18 T 28-03-2018 MKLM6_RS02345 92ec8cccac20759b1e4076151cdd32a7 299 SMART SM00220 26 297 4.6E-14 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MKLM6_RS02345 92ec8cccac20759b1e4076151cdd32a7 299 SUPERFAMILY SSF56112 8 294 1.17E-48 T 28-03-2018 IPR011009 Protein kinase-like domain MKLM6_RS15795 bfd1f73f3c3f67f21d972f816d3c7edb 259 TIGRFAM TIGR02623 G1P_cyt_trans: glucose-1-phosphate cytidylyltransferase 1 256 1.2E-143 T 28-03-2018 IPR013446 Glucose-1-phosphate cytidylyltransferase GO:0047343 KEGG: 00500+2.7.7.33|KEGG: 00520+2.7.7.33|MetaCyc: PWY-5833|MetaCyc: PWY-5940 MKLM6_RS15795 bfd1f73f3c3f67f21d972f816d3c7edb 259 Pfam PF00483 Nucleotidyl transferase 2 200 4.2E-17 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MKLM6_RS15795 bfd1f73f3c3f67f21d972f816d3c7edb 259 SUPERFAMILY SSF53448 1 256 4.77E-67 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS15795 bfd1f73f3c3f67f21d972f816d3c7edb 259 Gene3D G3DSA:3.90.550.10 1 257 1.1E-47 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS04905 5f03556d60619ab5867831f3bb446011 193 Pfam PF13689 Domain of unknown function (DUF4154) 42 184 1.7E-39 T 28-03-2018 IPR025293 Protein of unknown function DUF4154 MKLM6_RS03795 35e8e05f45a9e9a72dd40ee89902e1e9 161 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 70 1.0E-8 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MKLM6_RS03795 35e8e05f45a9e9a72dd40ee89902e1e9 161 SUPERFAMILY SSF53254 1 146 2.55E-18 T 28-03-2018 IPR029033 Histidine phosphatase superfamily MKLM6_RS03795 35e8e05f45a9e9a72dd40ee89902e1e9 161 PIRSF PIRSF000709 2 72 0.0014 T 28-03-2018 MKLM6_RS03795 35e8e05f45a9e9a72dd40ee89902e1e9 161 Gene3D G3DSA:3.40.50.1240 1 155 8.6E-20 T 28-03-2018 IPR029033 Histidine phosphatase superfamily MKLM6_RS03795 35e8e05f45a9e9a72dd40ee89902e1e9 161 SMART SM00855 2 118 4.0E-4 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MKLM6_RS09375 f6b6b3fd1777a7bc6be3b39baefebb7c 299 Pfam PF13488 Glycine zipper 35 80 2.4E-7 T 28-03-2018 MKLM6_RS09375 f6b6b3fd1777a7bc6be3b39baefebb7c 299 SUPERFAMILY SSF103088 109 214 4.32E-37 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS09375 f6b6b3fd1777a7bc6be3b39baefebb7c 299 Gene3D G3DSA:3.30.1330.60 74 249 3.7E-44 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS09375 f6b6b3fd1777a7bc6be3b39baefebb7c 299 Pfam PF00691 OmpA family 113 208 5.5E-23 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS09375 f6b6b3fd1777a7bc6be3b39baefebb7c 299 ProSitePatterns PS01068 OmpA-like domain. 146 190 - T 28-03-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 MKLM6_RS09375 f6b6b3fd1777a7bc6be3b39baefebb7c 299 PRINTS PR01021 OMPA domain signature 159 175 2.3E-16 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MKLM6_RS09375 f6b6b3fd1777a7bc6be3b39baefebb7c 299 PRINTS PR01021 OMPA domain signature 114 136 2.3E-16 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MKLM6_RS09375 f6b6b3fd1777a7bc6be3b39baefebb7c 299 PRINTS PR01021 OMPA domain signature 144 159 2.3E-16 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MKLM6_RS02830 2c15fee18d36deca30ef2c71ca93ecf7 432 Pfam PF04932 O-Antigen ligase 201 358 2.0E-18 T 28-03-2018 IPR007016 O-antigen ligase-related MKLM6_RS06725 6abc4846309ea677cfaab8e141ba39ab 83 SUPERFAMILY SSF143120 1 81 8.24E-26 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MKLM6_RS06725 6abc4846309ea677cfaab8e141ba39ab 83 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 56 7.9E-12 T 28-03-2018 MKLM6_RS06725 6abc4846309ea677cfaab8e141ba39ab 83 Gene3D G3DSA:3.40.1620.10 1 39 1.5E-18 T 28-03-2018 MKLM6_RS06725 6abc4846309ea677cfaab8e141ba39ab 83 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 74 8.4E-25 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MKLM6_RS13635 786547670d28dd9561950a49f88f531d 275 Pfam PF04326 Putative DNA-binding domain 122 258 5.7E-14 T 28-03-2018 IPR007421 Schlafen, AAA domain GO:0005524 MKLM6_RS22050 0a0d456fc63a39f31185c822edcad9e4 399 Pfam PF11348 Protein of unknown function (DUF3150) 8 266 7.6E-92 T 28-03-2018 IPR021496 Protein of unknown function DUF3150 MKLM6_RS00020 c2876c91928453adec1459e2190f5cb9 435 Pfam PF11902 Protein of unknown function (DUF3422) 10 427 2.7E-158 T 28-03-2018 IPR021830 Protein of unknown function DUF3422 MKLM6_RS05620 68c86f8c9d2d6bed9b9ae3ccd655516b 303 SUPERFAMILY SSF103481 48 142 1.7E-11 T 28-03-2018 MKLM6_RS05620 68c86f8c9d2d6bed9b9ae3ccd655516b 303 Pfam PF00892 EamA-like transporter family 13 141 2.8E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MKLM6_RS05620 68c86f8c9d2d6bed9b9ae3ccd655516b 303 Pfam PF00892 EamA-like transporter family 156 285 3.6E-13 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MKLM6_RS05620 68c86f8c9d2d6bed9b9ae3ccd655516b 303 SUPERFAMILY SSF103481 188 286 1.44E-10 T 28-03-2018 MKLM6_RS06315 98d12f6f4dcaf04fd86e02c0a3360ff4 116 Gene3D G3DSA:2.40.10.220 31 114 3.5E-6 T 28-03-2018 MKLM6_RS06315 98d12f6f4dcaf04fd86e02c0a3360ff4 116 Pfam PF07238 PilZ domain 14 104 4.3E-10 T 28-03-2018 IPR009875 PilZ domain GO:0035438 MKLM6_RS10760 8619c6d76ef593b49affc36fb75c316d 276 Pfam PF08668 HDOD domain 15 205 3.9E-45 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD MKLM6_RS10760 8619c6d76ef593b49affc36fb75c316d 276 Gene3D G3DSA:1.10.3210.10 1 242 1.5E-33 T 28-03-2018 MKLM6_RS10760 8619c6d76ef593b49affc36fb75c316d 276 SUPERFAMILY SSF109604 5 267 3.35E-52 T 28-03-2018 MKLM6_RS14510 5a264f8546e4424894c2ffc5eb1bd1ef 548 SUPERFAMILY SSF52091 454 532 4.71E-6 T 28-03-2018 IPR002645 STAS domain MKLM6_RS14510 5a264f8546e4424894c2ffc5eb1bd1ef 548 Pfam PF00916 Sulfate permease family 22 414 1.1E-57 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MKLM6_RS14510 5a264f8546e4424894c2ffc5eb1bd1ef 548 Gene3D G3DSA:3.30.750.24 449 535 6.0E-5 T 28-03-2018 IPR002645 STAS domain MKLM6_RS10360 b49c81c1603d6572eaf6544155799f23 750 Gene3D G3DSA:1.20.1250.20 282 644 1.8E-4 T 28-03-2018 MKLM6_RS03310 9b62b9e925cfc9f01b665659225ca8b0 98 Gene3D G3DSA:3.10.180.10 1 63 3.7E-9 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MKLM6_RS03310 9b62b9e925cfc9f01b665659225ca8b0 98 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 34 2.6E-4 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MKLM6_RS03310 9b62b9e925cfc9f01b665659225ca8b0 98 Gene3D G3DSA:3.10.180.10 64 97 0.0022 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MKLM6_RS03310 9b62b9e925cfc9f01b665659225ca8b0 98 SUPERFAMILY SSF54593 3 94 1.0E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MKLM6_RS03255 69637deeb0899313d169d0c77110733e 283 SUPERFAMILY SSF102114 35 243 7.06E-15 T 28-03-2018 MKLM6_RS03255 69637deeb0899313d169d0c77110733e 283 Pfam PF04055 Radical SAM superfamily 39 203 5.8E-8 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS03255 69637deeb0899313d169d0c77110733e 283 Gene3D G3DSA:3.20.20.70 24 280 8.6E-21 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS03440 2698c4e170b191c491cf0d4ff8499625 366 Gene3D G3DSA:1.20.1250.20 33 216 5.5E-4 T 28-03-2018 MKLM6_RS09235 c9c1a9b638ec17adaaba8a8802e9ef5c 375 PIRSF PIRSF015658 1 375 2.8E-174 T 28-03-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 MKLM6_RS09235 c9c1a9b638ec17adaaba8a8802e9ef5c 375 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 20 373 6.3E-157 T 28-03-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 MKLM6_RS09235 c9c1a9b638ec17adaaba8a8802e9ef5c 375 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 20 369 2.0E-172 T 28-03-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 MKLM6_RS19750 457d87c5b1f98b71fb93de0a09e2a8d7 174 Pfam PF01797 Transposase IS200 like 14 131 2.3E-6 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS19750 457d87c5b1f98b71fb93de0a09e2a8d7 174 Gene3D G3DSA:3.30.70.1290 1 138 3.8E-35 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS19750 457d87c5b1f98b71fb93de0a09e2a8d7 174 SMART SM01321 9 132 7.4E-34 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS19750 457d87c5b1f98b71fb93de0a09e2a8d7 174 SUPERFAMILY SSF143422 1 138 6.15E-33 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS07535 51e808dcf76f9b15505156e5e64c5f9a 197 SUPERFAMILY SSF116734 5 189 8.01E-24 T 28-03-2018 MKLM6_RS07535 51e808dcf76f9b15505156e5e64c5f9a 197 Gene3D G3DSA:3.90.220.20 2 179 5.7E-17 T 28-03-2018 MKLM6_RS07535 51e808dcf76f9b15505156e5e64c5f9a 197 Pfam PF01420 Type I restriction modification DNA specificity domain 60 158 2.9E-6 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MKLM6_RS05745 0c442d51e2c689845003dea33b3d4d9b 261 Pfam PF02535 ZIP Zinc transporter 102 251 2.5E-27 T 28-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 MKLM6_RS05745 0c442d51e2c689845003dea33b3d4d9b 261 Pfam PF02535 ZIP Zinc transporter 10 97 7.5E-12 T 28-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 MKLM6_RS08510 891671f8436a630cf16b22111ae88709 452 Pfam PF02754 Cysteine-rich domain 346 422 0.0071 T 28-03-2018 IPR004017 Cysteine-rich domain MKLM6_RS08510 891671f8436a630cf16b22111ae88709 452 Gene3D G3DSA:1.10.1060.10 12 129 3.7E-12 T 28-03-2018 MKLM6_RS08510 891671f8436a630cf16b22111ae88709 452 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 96 107 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MKLM6_RS08510 891671f8436a630cf16b22111ae88709 452 Pfam PF13183 4Fe-4S dicluster domain 35 109 4.8E-7 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MKLM6_RS11395 13b8af1d78e3c1454550030721b9ccae 401 SUPERFAMILY SSF53218 4 203 5.76E-35 T 28-03-2018 IPR001453 MoaB/Mog domain MKLM6_RS11395 13b8af1d78e3c1454550030721b9ccae 401 SMART SM00852 6 173 1.0E-34 T 28-03-2018 IPR001453 MoaB/Mog domain MKLM6_RS11395 13b8af1d78e3c1454550030721b9ccae 401 Pfam PF00994 Probable molybdopterin binding domain 7 166 3.7E-29 T 28-03-2018 IPR001453 MoaB/Mog domain MKLM6_RS11395 13b8af1d78e3c1454550030721b9ccae 401 Gene3D G3DSA:3.40.980.10 2 173 7.5E-40 T 28-03-2018 IPR001453 MoaB/Mog domain MKLM6_RS07630 223ab88e76b6c503f301fbb234adfd58 345 Gene3D G3DSA:3.30.70.270 183 344 5.9E-49 T 28-03-2018 MKLM6_RS07630 223ab88e76b6c503f301fbb234adfd58 345 Pfam PF00990 Diguanylate cyclase, GGDEF domain 184 341 8.4E-42 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS07630 223ab88e76b6c503f301fbb234adfd58 345 Gene3D G3DSA:1.20.58.400 54 182 0.0016 T 28-03-2018 MKLM6_RS07630 223ab88e76b6c503f301fbb234adfd58 345 SUPERFAMILY SSF55073 189 343 9.42E-43 T 28-03-2018 IPR029787 Nucleotide cyclase MKLM6_RS07630 223ab88e76b6c503f301fbb234adfd58 345 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 182 343 8.4E-46 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS07630 223ab88e76b6c503f301fbb234adfd58 345 SMART SM00267 173 345 1.6E-46 T 28-03-2018 IPR000160 GGDEF domain MKLM6_RS01910 900db722fada429ae9b12f8f3bc735ab 621 Gene3D G3DSA:3.30.2010.10 101 192 2.9E-10 T 28-03-2018 MKLM6_RS01910 900db722fada429ae9b12f8f3bc735ab 621 Pfam PF01435 Peptidase family M48 151 340 3.0E-12 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MKLM6_RS02205 d54cda781ac786bcb26717f26d747321 566 SUPERFAMILY SSF90123 30 349 1.2E-21 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MKLM6_RS02205 d54cda781ac786bcb26717f26d747321 566 Pfam PF06472 ABC transporter transmembrane region 2 5 297 5.4E-47 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MKLM6_RS02205 d54cda781ac786bcb26717f26d747321 566 Gene3D G3DSA:3.40.50.300 370 563 2.1E-13 T 28-03-2018 MKLM6_RS02205 d54cda781ac786bcb26717f26d747321 566 SUPERFAMILY SSF52540 356 555 5.82E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS02205 d54cda781ac786bcb26717f26d747321 566 Gene3D G3DSA:1.20.1560.10 5 354 2.5E-32 T 28-03-2018 MKLM6_RS10485 7c3dc9f69b53e27ea43798086dcecab4 373 Gene3D G3DSA:3.40.50.300 35 212 6.4E-25 T 28-03-2018 MKLM6_RS10485 7c3dc9f69b53e27ea43798086dcecab4 373 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 253 262 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site MKLM6_RS10485 7c3dc9f69b53e27ea43798086dcecab4 373 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 64 77 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MKLM6_RS10485 7c3dc9f69b53e27ea43798086dcecab4 373 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 126 141 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MKLM6_RS10485 7c3dc9f69b53e27ea43798086dcecab4 373 Gene3D G3DSA:1.10.8.60 213 284 8.2E-22 T 28-03-2018 MKLM6_RS10485 7c3dc9f69b53e27ea43798086dcecab4 373 SUPERFAMILY SSF52540 41 281 1.86E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS10485 7c3dc9f69b53e27ea43798086dcecab4 373 Pfam PF02954 Bacterial regulatory protein, Fis family 317 354 7.6E-5 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MKLM6_RS10485 7c3dc9f69b53e27ea43798086dcecab4 373 Pfam PF00158 Sigma-54 interaction domain 42 207 4.6E-67 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MKLM6_RS10485 7c3dc9f69b53e27ea43798086dcecab4 373 SUPERFAMILY SSF46689 253 358 2.02E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS10485 7c3dc9f69b53e27ea43798086dcecab4 373 SMART SM00382 60 203 1.3E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS10485 7c3dc9f69b53e27ea43798086dcecab4 373 Gene3D G3DSA:1.10.10.60 292 360 1.4E-8 T 28-03-2018 MKLM6_RS15520 4db5e8887b059f59747c6d7576c72ea0 204 Gene3D G3DSA:3.30.930.10 1 203 1.3E-57 T 28-03-2018 MKLM6_RS15520 4db5e8887b059f59747c6d7576c72ea0 204 SUPERFAMILY SSF55681 3 201 8.29E-64 T 28-03-2018 MKLM6_RS15520 4db5e8887b059f59747c6d7576c72ea0 204 Hamap MF_00013 Octanoyltransferase [lipB]. 4 201 34.261 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MKLM6_RS15520 4db5e8887b059f59747c6d7576c72ea0 204 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 70 85 - T 28-03-2018 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 MKLM6_RS15520 4db5e8887b059f59747c6d7576c72ea0 204 Pfam PF03099 Biotin/lipoate A/B protein ligase family 55 158 8.8E-6 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 MKLM6_RS15520 4db5e8887b059f59747c6d7576c72ea0 204 PIRSF PIRSF016262 1 203 8.5E-55 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MKLM6_RS15520 4db5e8887b059f59747c6d7576c72ea0 204 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 74 127 1.0E-12 T 28-03-2018 MKLM6_RS15520 4db5e8887b059f59747c6d7576c72ea0 204 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 27 200 9.9E-54 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MKLM6_RS21135 562d3d02cd843fc72ee67b393eb98386 296 Gene3D G3DSA:3.30.1490.20 115 170 3.0E-11 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MKLM6_RS21135 562d3d02cd843fc72ee67b393eb98386 296 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 2 286 2.6E-86 T 28-03-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 MKLM6_RS21135 562d3d02cd843fc72ee67b393eb98386 296 Hamap MF_01552 Ribosomal protein S6--L-glutamate ligase [rimK]. 1 295 53.198 T 28-03-2018 IPR023533 Ribosomal protein S6--L-glutamate ligase RimK MKLM6_RS21135 562d3d02cd843fc72ee67b393eb98386 296 Pfam PF08443 RimK-like ATP-grasp domain 98 286 1.7E-68 T 28-03-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 MKLM6_RS21135 562d3d02cd843fc72ee67b393eb98386 296 Gene3D G3DSA:3.30.470.20 171 277 4.0E-34 T 28-03-2018 MKLM6_RS21135 562d3d02cd843fc72ee67b393eb98386 296 Gene3D G3DSA:3.40.50.20 1 114 3.3E-37 T 28-03-2018 MKLM6_RS21135 562d3d02cd843fc72ee67b393eb98386 296 SUPERFAMILY SSF56059 98 288 4.42E-49 T 28-03-2018 MKLM6_RS00095 8e820ad333a6663d348d1b1bb9a27780 336 Pfam PF11726 Inovirus Gp2 151 320 2.1E-22 T 28-03-2018 MKLM6_RS01680 e2f32148b344a0bcbf90407aca19edff 304 Gene3D G3DSA:1.20.58.180 218 294 8.7E-36 T 28-03-2018 MKLM6_RS01680 e2f32148b344a0bcbf90407aca19edff 304 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 10 299 8.2E-168 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MKLM6_RS01680 e2f32148b344a0bcbf90407aca19edff 304 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 11 292 2.5E-152 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MKLM6_RS01680 e2f32148b344a0bcbf90407aca19edff 304 Gene3D G3DSA:3.30.930.10 1 216 3.1E-88 T 28-03-2018 MKLM6_RS01680 e2f32148b344a0bcbf90407aca19edff 304 SUPERFAMILY SSF55681 10 292 1.27E-137 T 28-03-2018 MKLM6_RS01680 e2f32148b344a0bcbf90407aca19edff 304 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 9 293 62.191 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MKLM6_RS01680 e2f32148b344a0bcbf90407aca19edff 304 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 141 161 3.0E-70 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MKLM6_RS01680 e2f32148b344a0bcbf90407aca19edff 304 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 164 179 3.0E-70 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MKLM6_RS01680 e2f32148b344a0bcbf90407aca19edff 304 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 63 78 3.0E-70 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MKLM6_RS01680 e2f32148b344a0bcbf90407aca19edff 304 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 84 104 3.0E-70 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MKLM6_RS01680 e2f32148b344a0bcbf90407aca19edff 304 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 253 269 3.0E-70 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MKLM6_RS01680 e2f32148b344a0bcbf90407aca19edff 304 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 115 139 3.0E-70 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MKLM6_RS03925 f921f22f4993bc943b5247a71c39b2a8 204 Gene3D G3DSA:1.10.287.950 8 79 3.8E-7 T 28-03-2018 MKLM6_RS03925 f921f22f4993bc943b5247a71c39b2a8 204 Gene3D G3DSA:1.10.287.950 86 202 0.014 T 28-03-2018 MKLM6_RS03925 f921f22f4993bc943b5247a71c39b2a8 204 SUPERFAMILY SSF58104 13 91 1.22E-6 T 28-03-2018 MKLM6_RS02255 ba226292c2921669a2349b4e27f90977 154 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 154 27.641 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MKLM6_RS02255 ba226292c2921669a2349b4e27f90977 154 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 154 7.1E-58 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MKLM6_RS02255 ba226292c2921669a2349b4e27f90977 154 Pfam PF02590 Predicted SPOUT methyltransferase 1 153 5.3E-49 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MKLM6_RS02255 ba226292c2921669a2349b4e27f90977 154 PIRSF PIRSF004505 1 154 2.3E-43 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MKLM6_RS02255 ba226292c2921669a2349b4e27f90977 154 SUPERFAMILY SSF75217 1 152 6.28E-47 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases MKLM6_RS02255 ba226292c2921669a2349b4e27f90977 154 Gene3D G3DSA:3.40.1280.10 1 154 1.6E-50 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MKLM6_RS16585 d3b64ad9ba44c39a75b89169f9f9e179 355 Pfam PF01594 AI-2E family transporter 7 342 2.1E-60 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like MKLM6_RS15125 96bfaecc7162f89aca380f696144318c 240 Hamap MF_00478 Electron transport complex subunit RsxE [rsxE]. 11 217 26.159 T 28-03-2018 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 MKLM6_RS15125 96bfaecc7162f89aca380f696144318c 240 PIRSF PIRSF006102 7 224 4.8E-75 T 28-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 MKLM6_RS15125 96bfaecc7162f89aca380f696144318c 240 Pfam PF02508 Rnf-Nqr subunit, membrane protein 12 206 3.1E-61 T 28-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 MKLM6_RS15125 96bfaecc7162f89aca380f696144318c 240 TIGRFAM TIGR01948 rnfE: electron transport complex, RnfABCDGE type, E subunit 13 215 2.8E-77 T 28-03-2018 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 MKLM6_RS19135 38d719f4b88c8e36e3fcc6fdb2c7d5b2 271 Pfam PF10977 Protein of unknown function (DUF2797) 34 267 1.8E-98 T 28-03-2018 IPR021246 Protein of unknown function DUF2797 MKLM6_RS09035 4cd775aea93ac6f71e7104397fff551c 126 Gene3D G3DSA:3.30.420.130 2 126 2.1E-16 T 28-03-2018 MKLM6_RS09035 4cd775aea93ac6f71e7104397fff551c 126 SUPERFAMILY SSF53146 5 110 4.84E-16 T 28-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis MKLM6_RS13865 f59906d90cacfe4fd14661c15e7c70c0 312 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 9 306 30.901 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MKLM6_RS13865 f59906d90cacfe4fd14661c15e7c70c0 312 Gene3D G3DSA:3.40.50.300 5 201 2.2E-66 T 28-03-2018 MKLM6_RS13865 f59906d90cacfe4fd14661c15e7c70c0 312 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 9 293 1.9E-102 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MKLM6_RS13865 f59906d90cacfe4fd14661c15e7c70c0 312 SUPERFAMILY SSF52540 10 154 7.59E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS13865 f59906d90cacfe4fd14661c15e7c70c0 312 Pfam PF01715 IPP transferase 43 289 1.2E-87 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MKLM6_RS13865 f59906d90cacfe4fd14661c15e7c70c0 312 Gene3D G3DSA:1.10.287.890 205 287 3.2E-25 T 28-03-2018 MKLM6_RS10130 16bb0f3bc47d6e8171685f6391f9d883 253 PIRSF PIRSF009320 92 252 2.0E-8 T 28-03-2018 MKLM6_RS10130 16bb0f3bc47d6e8171685f6391f9d883 253 PIRSF PIRSF009320 3 49 4.2E-14 T 28-03-2018 MKLM6_RS10130 16bb0f3bc47d6e8171685f6391f9d883 253 Gene3D G3DSA:3.40.50.300 2 251 7.5E-52 T 28-03-2018 MKLM6_RS10130 16bb0f3bc47d6e8171685f6391f9d883 253 Pfam PF13614 AAA domain 4 175 2.6E-40 T 28-03-2018 IPR025669 AAA domain MKLM6_RS10130 16bb0f3bc47d6e8171685f6391f9d883 253 SUPERFAMILY SSF52540 2 251 2.35E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS02330 f47d7a70ccdb6b64498d7d62218eb983 387 Pfam PF01636 Phosphotransferase enzyme family 50 286 1.7E-29 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase MKLM6_RS02330 f47d7a70ccdb6b64498d7d62218eb983 387 Gene3D G3DSA:3.90.1200.10 142 373 2.5E-23 T 28-03-2018 MKLM6_RS02330 f47d7a70ccdb6b64498d7d62218eb983 387 SUPERFAMILY SSF56112 32 366 8.55E-44 T 28-03-2018 IPR011009 Protein kinase-like domain MKLM6_RS02330 f47d7a70ccdb6b64498d7d62218eb983 387 Gene3D G3DSA:3.30.200.20 25 137 1.2E-13 T 28-03-2018 MKLM6_RS12675 b7aecdcb692aa2324566324a7de978e7 342 Gene3D G3DSA:3.10.520.10 27 335 8.7E-50 T 28-03-2018 MKLM6_RS12675 b7aecdcb692aa2324566324a7de978e7 342 PIRSF PIRSF006268 6 338 1.8E-79 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 MKLM6_RS12675 b7aecdcb692aa2324566324a7de978e7 342 Pfam PF02424 ApbE family 36 317 4.7E-77 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 MKLM6_RS12675 b7aecdcb692aa2324566324a7de978e7 342 SUPERFAMILY SSF143631 28 332 4.97E-81 T 28-03-2018 IPR003374 ApbE-like domain MKLM6_RS18960 b7ceca643bb48cfd159e4082681cb940 144 SMART SM00248 84 113 0.48 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 MKLM6_RS18960 b7ceca643bb48cfd159e4082681cb940 144 SMART SM00248 51 80 0.0069 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 MKLM6_RS18960 b7ceca643bb48cfd159e4082681cb940 144 SMART SM00248 17 47 7.5 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 MKLM6_RS18960 b7ceca643bb48cfd159e4082681cb940 144 Gene3D G3DSA:1.25.40.20 6 61 9.3E-12 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain MKLM6_RS18960 b7ceca643bb48cfd159e4082681cb940 144 Pfam PF12796 Ankyrin repeats (3 copies) 17 81 6.0E-9 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain MKLM6_RS18960 b7ceca643bb48cfd159e4082681cb940 144 Pfam PF00023 Ankyrin repeat 85 110 0.026 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 MKLM6_RS18960 b7ceca643bb48cfd159e4082681cb940 144 Gene3D G3DSA:1.25.40.20 62 139 1.6E-21 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain MKLM6_RS18960 b7ceca643bb48cfd159e4082681cb940 144 SUPERFAMILY SSF48403 16 137 1.71E-28 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain MKLM6_RS17435 5d0ce3d8964f5ab800c02a94154ee1e9 451 SUPERFAMILY SSF55874 324 444 1.58E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS17435 5d0ce3d8964f5ab800c02a94154ee1e9 451 Pfam PF07730 Histidine kinase 247 314 2.7E-12 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MKLM6_RS17435 5d0ce3d8964f5ab800c02a94154ee1e9 451 Gene3D G3DSA:3.30.565.10 311 451 1.4E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MKLM6_RS17435 5d0ce3d8964f5ab800c02a94154ee1e9 451 SMART SM00304 179 231 0.0094 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MKLM6_RS18070 1b656d7611956a0fcbe93b53ce5c6c39 235 SUPERFAMILY SSF53448 10 231 4.16E-44 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS18070 1b656d7611956a0fcbe93b53ce5c6c39 235 Pfam PF02348 Cytidylyltransferase 9 225 6.4E-19 T 28-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 MKLM6_RS18070 1b656d7611956a0fcbe93b53ce5c6c39 235 Gene3D G3DSA:3.90.550.10 5 233 4.5E-23 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS04045 3aa258f398a28d90921d47c89c83e7da 235 Pfam PF16258 Domain of unknown function (DUF4912) 75 189 7.2E-8 T 28-03-2018 IPR032585 Protein of unknown function DUF4912 MKLM6_RS10295 7b2bdf9f620492e3f32dd5ed2cc40245 263 Pfam PF03705 CheR methyltransferase, all-alpha domain 4 51 3.8E-16 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MKLM6_RS10295 7b2bdf9f620492e3f32dd5ed2cc40245 263 SUPERFAMILY SSF47757 1 70 8.63E-19 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MKLM6_RS10295 7b2bdf9f620492e3f32dd5ed2cc40245 263 SUPERFAMILY SSF53335 71 261 4.73E-58 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS10295 7b2bdf9f620492e3f32dd5ed2cc40245 263 Gene3D G3DSA:3.40.50.150 70 263 2.3E-52 T 28-03-2018 MKLM6_RS10295 7b2bdf9f620492e3f32dd5ed2cc40245 263 Pfam PF01739 CheR methyltransferase, SAM binding domain 71 253 1.3E-53 T 28-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal MKLM6_RS10295 7b2bdf9f620492e3f32dd5ed2cc40245 263 PRINTS PR00996 Glutamate methyltransferase family signature 131 147 6.3E-41 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS10295 7b2bdf9f620492e3f32dd5ed2cc40245 263 PRINTS PR00996 Glutamate methyltransferase family signature 25 38 6.3E-41 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS10295 7b2bdf9f620492e3f32dd5ed2cc40245 263 PRINTS PR00996 Glutamate methyltransferase family signature 203 217 6.3E-41 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS10295 7b2bdf9f620492e3f32dd5ed2cc40245 263 PRINTS PR00996 Glutamate methyltransferase family signature 222 245 6.3E-41 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS10295 7b2bdf9f620492e3f32dd5ed2cc40245 263 PRINTS PR00996 Glutamate methyltransferase family signature 64 76 6.3E-41 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS10295 7b2bdf9f620492e3f32dd5ed2cc40245 263 PRINTS PR00996 Glutamate methyltransferase family signature 99 119 6.3E-41 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS10295 7b2bdf9f620492e3f32dd5ed2cc40245 263 SMART SM00138 3 263 4.4E-87 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MKLM6_RS10295 7b2bdf9f620492e3f32dd5ed2cc40245 263 Gene3D G3DSA:1.10.155.10 1 69 1.3E-19 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MKLM6_RS10295 7b2bdf9f620492e3f32dd5ed2cc40245 263 PIRSF PIRSF000410 1 263 3.0E-96 T 28-03-2018 IPR026024 Chemotaxis protein methyltransferase CheR MKLM6_RS20105 3f0b9bc0af3e0b55e31791a599f967bb 654 SMART SM00220 47 332 5.5E-38 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MKLM6_RS20105 3f0b9bc0af3e0b55e31791a599f967bb 654 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 176 188 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MKLM6_RS20105 3f0b9bc0af3e0b55e31791a599f967bb 654 Gene3D G3DSA:1.10.510.10 167 433 1.1E-32 T 28-03-2018 MKLM6_RS20105 3f0b9bc0af3e0b55e31791a599f967bb 654 Gene3D G3DSA:3.30.200.20 22 166 2.4E-24 T 28-03-2018 MKLM6_RS20105 3f0b9bc0af3e0b55e31791a599f967bb 654 Gene3D G3DSA:3.30.450.20 519 651 1.5E-5 T 28-03-2018 MKLM6_RS20105 3f0b9bc0af3e0b55e31791a599f967bb 654 SUPERFAMILY SSF56112 42 326 4.45E-54 T 28-03-2018 IPR011009 Protein kinase-like domain MKLM6_RS20105 3f0b9bc0af3e0b55e31791a599f967bb 654 Pfam PF00069 Protein kinase domain 49 319 3.9E-38 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MKLM6_RS08860 88b4a7fde8f4d8c2a7598289fcf83087 264 SUPERFAMILY SSF46565 3 66 7.63E-7 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS08860 88b4a7fde8f4d8c2a7598289fcf83087 264 Gene3D G3DSA:1.10.287.110 1 67 1.3E-7 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS16525 278b71cbb926ff169348cdea26a1dd7d 208 Gene3D G3DSA:2.60.40.680 12 173 6.7E-9 T 28-03-2018 MKLM6_RS13065 4a8682da79f25b8725fda5cab1f9d65e 295 PIRSF PIRSF006221 5 295 5.7E-94 T 28-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 MKLM6_RS13065 4a8682da79f25b8725fda5cab1f9d65e 295 Gene3D G3DSA:3.90.1200.10 95 286 1.7E-17 T 28-03-2018 MKLM6_RS13065 4a8682da79f25b8725fda5cab1f9d65e 295 Gene3D G3DSA:3.30.200.20 3 94 7.9E-24 T 28-03-2018 MKLM6_RS13065 4a8682da79f25b8725fda5cab1f9d65e 295 Pfam PF03881 Fructosamine kinase 8 292 3.1E-101 T 28-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 MKLM6_RS13065 4a8682da79f25b8725fda5cab1f9d65e 295 SUPERFAMILY SSF56112 8 287 2.72E-39 T 28-03-2018 IPR011009 Protein kinase-like domain MKLM6_RS11895 f18dadae57f0aab8fa053360d50d08f5 157 Gene3D G3DSA:3.40.50.1010 1 157 3.0E-33 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS11895 f18dadae57f0aab8fa053360d50d08f5 157 Pfam PF01936 NYN domain 3 150 1.1E-38 T 28-03-2018 IPR021139 NYN domain, limkain-b1-type MKLM6_RS18050 3881a1780697b3d2791f72a32bd6672d 241 Gene3D G3DSA:1.10.760.10 87 235 1.1E-9 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS18050 3881a1780697b3d2791f72a32bd6672d 241 SUPERFAMILY SSF46626 142 227 1.0E-12 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS14560 cddc0dfd4ec43f71946a68724a2af984 107 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 13 102 28.769 T 28-03-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS MKLM6_RS14560 cddc0dfd4ec43f71946a68724a2af984 107 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 24 103 1.4E-34 T 28-03-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 MKLM6_RS14560 cddc0dfd4ec43f71946a68724a2af984 107 SUPERFAMILY SSF54736 22 106 5.75E-33 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MKLM6_RS14560 cddc0dfd4ec43f71946a68724a2af984 107 Gene3D G3DSA:3.30.1390.10 14 106 2.8E-37 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MKLM6_RS17060 5690b3b4a326dcf476c6c5dd96f1e99f 202 Gene3D G3DSA:1.10.10.10 101 201 1.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS17060 5690b3b4a326dcf476c6c5dd96f1e99f 202 Pfam PF00196 Bacterial regulatory proteins, luxR family 136 186 2.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS17060 5690b3b4a326dcf476c6c5dd96f1e99f 202 SUPERFAMILY SSF46894 125 198 3.74E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MKLM6_RS17060 5690b3b4a326dcf476c6c5dd96f1e99f 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 167 9.7E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS17060 5690b3b4a326dcf476c6c5dd96f1e99f 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 137 151 9.7E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS17060 5690b3b4a326dcf476c6c5dd96f1e99f 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 179 9.7E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS17060 5690b3b4a326dcf476c6c5dd96f1e99f 202 SMART SM00421 134 191 1.5E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MKLM6_RS19710 9826d4ae53037fdeba2b6b1f3446b176 278 SUPERFAMILY SSF53474 47 265 6.19E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS19710 9826d4ae53037fdeba2b6b1f3446b176 278 Gene3D G3DSA:3.40.50.1820 28 270 4.5E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS19710 9826d4ae53037fdeba2b6b1f3446b176 278 Pfam PF00561 alpha/beta hydrolase fold 48 178 3.6E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS22200 dc61eda2b453c57d3e7383d09ddc1438 245 TIGRFAM TIGR03736 PRTRC_ThiF: PRTRC system ThiF family protein 10 244 2.1E-72 T 28-03-2018 IPR022500 ParB-related, ThiF-related cassette, ThiF MKLM6_RS22200 dc61eda2b453c57d3e7383d09ddc1438 245 SUPERFAMILY SSF69572 19 218 3.79E-18 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MKLM6_RS22200 dc61eda2b453c57d3e7383d09ddc1438 245 Gene3D G3DSA:3.40.50.720 17 243 4.5E-22 T 28-03-2018 MKLM6_RS22200 dc61eda2b453c57d3e7383d09ddc1438 245 Pfam PF00899 ThiF family 18 166 1.5E-14 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MKLM6_RS18785 445e3b1b308a98a30216c65f454751b5 138 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 76 134 3.1E-11 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain MKLM6_RS18785 445e3b1b308a98a30216c65f454751b5 138 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site MKLM6_RS18785 445e3b1b308a98a30216c65f454751b5 138 Pfam PF00460 Flagella basal body rod protein 7 32 8.8E-6 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 MKLM6_RS18785 445e3b1b308a98a30216c65f454751b5 138 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 5 138 1.5E-47 T 28-03-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 MKLM6_RS00970 39950628e41a494fa1b342e6bdcdadaf 405 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 166 194 - T 28-03-2018 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 MKLM6_RS00970 39950628e41a494fa1b342e6bdcdadaf 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 166 194 2.1E-17 T 28-03-2018 IPR003004 GspF/PilC family MKLM6_RS00970 39950628e41a494fa1b342e6bdcdadaf 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 370 384 2.1E-17 T 28-03-2018 IPR003004 GspF/PilC family MKLM6_RS00970 39950628e41a494fa1b342e6bdcdadaf 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 67 79 2.1E-17 T 28-03-2018 IPR003004 GspF/PilC family MKLM6_RS00970 39950628e41a494fa1b342e6bdcdadaf 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 386 405 2.1E-17 T 28-03-2018 IPR003004 GspF/PilC family MKLM6_RS00970 39950628e41a494fa1b342e6bdcdadaf 405 Pfam PF00482 Type II secretion system (T2SS), protein F 71 194 5.1E-30 T 28-03-2018 IPR018076 Type II secretion system F domain MKLM6_RS00970 39950628e41a494fa1b342e6bdcdadaf 405 Pfam PF00482 Type II secretion system (T2SS), protein F 275 397 8.3E-32 T 28-03-2018 IPR018076 Type II secretion system F domain MKLM6_RS15135 31c9f1a381541955e8cd7579db521a64 353 Pfam PF03116 NQR2, RnfD, RnfE family 7 340 2.1E-103 T 28-03-2018 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 MKLM6_RS15135 31c9f1a381541955e8cd7579db521a64 353 Hamap MF_00462 Electron transport complex subunit RsxD [rsxD]. 3 342 26.301 T 28-03-2018 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 MKLM6_RS15135 31c9f1a381541955e8cd7579db521a64 353 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 9 341 2.5E-112 T 28-03-2018 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 MKLM6_RS05810 8379fd86df31618752915a885453dc49 130 Pfam PF01152 Bacterial-like globin 6 123 3.4E-39 T 28-03-2018 IPR001486 Truncated hemoglobin GO:0019825 MKLM6_RS05810 8379fd86df31618752915a885453dc49 130 SUPERFAMILY SSF46458 4 125 1.07E-34 T 28-03-2018 IPR009050 Globin-like MKLM6_RS05810 8379fd86df31618752915a885453dc49 130 Gene3D G3DSA:1.10.490.10 1 129 1.4E-30 T 28-03-2018 MKLM6_RS21190 c525fdec852e91b2fd32f0ed89a226f7 182 Pfam PF03167 Uracil DNA glycosylase superfamily 12 152 7.6E-31 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MKLM6_RS21190 c525fdec852e91b2fd32f0ed89a226f7 182 Gene3D G3DSA:3.40.470.10 3 174 9.3E-36 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MKLM6_RS21190 c525fdec852e91b2fd32f0ed89a226f7 182 SMART SM00987 6 167 3.0E-18 T 28-03-2018 MKLM6_RS21190 c525fdec852e91b2fd32f0ed89a226f7 182 SUPERFAMILY SSF52141 4 154 3.6E-32 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MKLM6_RS21190 c525fdec852e91b2fd32f0ed89a226f7 182 SMART SM00986 6 167 3.0E-18 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MKLM6_RS21710 dbe0df84d4c95bd6e58a5988f4943d79 397 Pfam PF11795 Uncharacterized protein conserved in bacteria N-term (DUF3322) 9 191 1.2E-54 T 28-03-2018 IPR024537 Domain of unknown function DUF3322 MKLM6_RS21710 dbe0df84d4c95bd6e58a5988f4943d79 397 Gene3D G3DSA:3.40.1360.10 237 389 2.2E-4 T 28-03-2018 MKLM6_RS21710 dbe0df84d4c95bd6e58a5988f4943d79 397 Pfam PF09983 Uncharacterized protein conserved in bacteria C-term(DUF2220) 214 387 6.9E-56 T 28-03-2018 IPR024534 Domain of unknown function DUF2220 MKLM6_RS21710 dbe0df84d4c95bd6e58a5988f4943d79 397 PIRSF PIRSF028408 3 397 2.4E-78 T 28-03-2018 IPR014544 Uncharacterised conserved protein UCP028408 MKLM6_RS20880 629be9f1a6f3b0518f359a8f157e4821 111 Pfam PF16785 Small metal-binding protein 2 108 1.5E-34 T 28-03-2018 IPR031877 Metal-binding protein SmbP GO:0046872 MKLM6_RS17535 3454de9e468ff74acdc8500bccd33e68 147 Gene3D G3DSA:3.10.180.10 1 117 7.9E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MKLM6_RS17535 3454de9e468ff74acdc8500bccd33e68 147 SUPERFAMILY SSF54593 2 118 8.32E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MKLM6_RS22340 b780c5eddeab2bcf5afd11c0dbfa905f 77 SMART SM00966 4 50 5.1E-9 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MKLM6_RS22340 b780c5eddeab2bcf5afd11c0dbfa905f 77 SUPERFAMILY SSF89447 1 65 3.84E-12 T 28-03-2018 MKLM6_RS22340 b780c5eddeab2bcf5afd11c0dbfa905f 77 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 39 1.0E-12 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MKLM6_RS22340 b780c5eddeab2bcf5afd11c0dbfa905f 77 Gene3D G3DSA:2.10.260.10 1 40 3.0E-13 T 28-03-2018 MKLM6_RS06570 9dd70a0b8b0c34bacdad6a63253fedb0 837 Pfam PF10101 Predicted membrane protein (DUF2339) 165 822 2.3E-91 T 28-03-2018 IPR019286 Protein of unknown function DUF2339, transmembrane MKLM6_RS18715 4dbfa64e7e07c7a83a924c7b9b63a659 112 Pfam PF01863 Protein of unknown function DUF45 6 99 9.9E-29 T 28-03-2018 IPR002725 Protein of unknown function DUF45 MKLM6_RS02210 ab48c2ade94603efa7110278d4061df8 75 Gene3D G3DSA:1.20.5.50 18 56 1.6E-5 T 28-03-2018 MKLM6_RS08400 035b0da91e74723928f42e935edcaecd 249 SUPERFAMILY SSF52317 1 198 2.37E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS08400 035b0da91e74723928f42e935edcaecd 249 Gene3D G3DSA:3.40.50.880 1 228 2.4E-39 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like MKLM6_RS08400 035b0da91e74723928f42e935edcaecd 249 Pfam PF00117 Glutamine amidotransferase class-I 42 178 3.7E-14 T 28-03-2018 IPR017926 Glutamine amidotransferase MKLM6_RS20675 4fdf8f6b347ec75732f21fd51467544d 275 SUPERFAMILY SSF103481 34 131 1.44E-7 T 28-03-2018 MKLM6_RS20675 4fdf8f6b347ec75732f21fd51467544d 275 Pfam PF00892 EamA-like transporter family 140 270 2.9E-11 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MKLM6_RS20675 4fdf8f6b347ec75732f21fd51467544d 275 SUPERFAMILY SSF103481 175 266 9.81E-11 T 28-03-2018 MKLM6_RS02780 b1b53e7126ffb7cace9e642513a705f2 366 Gene3D G3DSA:3.40.50.2300 2 140 1.1E-29 T 28-03-2018 MKLM6_RS02780 b1b53e7126ffb7cace9e642513a705f2 366 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 3 366 35.14 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MKLM6_RS02780 b1b53e7126ffb7cace9e642513a705f2 366 Gene3D G3DSA:3.40.50.180 172 366 1.5E-64 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MKLM6_RS02780 b1b53e7126ffb7cace9e642513a705f2 366 SUPERFAMILY SSF52172 2 108 1.35E-27 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS02780 b1b53e7126ffb7cace9e642513a705f2 366 Pfam PF00072 Response regulator receiver domain 5 110 2.1E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS02780 b1b53e7126ffb7cace9e642513a705f2 366 PIRSF PIRSF000876 1 366 3.8E-118 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MKLM6_RS02780 b1b53e7126ffb7cace9e642513a705f2 366 SUPERFAMILY SSF52738 179 365 1.96E-58 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MKLM6_RS02780 b1b53e7126ffb7cace9e642513a705f2 366 SMART SM00448 3 117 1.8E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS02780 b1b53e7126ffb7cace9e642513a705f2 366 Pfam PF01339 CheB methylesterase 184 361 1.6E-54 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MKLM6_RS07610 2d84daec9b3fff4267f4d5616c19eb50 318 SUPERFAMILY SSF55486 165 276 1.09E-10 T 28-03-2018 MKLM6_RS07610 2d84daec9b3fff4267f4d5616c19eb50 318 Pfam PF00413 Matrixin 151 196 2.4E-6 T 28-03-2018 IPR001818 Peptidase M10, metallopeptidase GO:0004222|GO:0006508|GO:0008270|GO:0031012 MKLM6_RS07610 2d84daec9b3fff4267f4d5616c19eb50 318 Gene3D G3DSA:3.40.390.10 17 274 8.3E-15 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 MKLM6_RS06870 e5a6cd8bc4343026e65eccb47f63f01d 282 SUPERFAMILY SSF109604 7 275 6.68E-63 T 28-03-2018 MKLM6_RS06870 e5a6cd8bc4343026e65eccb47f63f01d 282 Gene3D G3DSA:1.10.3210.10 2 274 3.6E-42 T 28-03-2018 MKLM6_RS06870 e5a6cd8bc4343026e65eccb47f63f01d 282 Pfam PF08668 HDOD domain 18 207 6.1E-58 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD MKLM6_RS02055 53e58bbfcbd56475ec4bab95c505c0a4 178 Gene3D G3DSA:1.10.287.110 109 177 2.3E-9 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS02055 53e58bbfcbd56475ec4bab95c505c0a4 178 SMART SM00271 122 178 0.0082 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS02055 53e58bbfcbd56475ec4bab95c505c0a4 178 SUPERFAMILY SSF46565 116 175 5.23E-12 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS05270 c170ef416cbdc9a374ba7a9f0ef163a5 536 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 46 241 4.4E-15 T 28-03-2018 IPR010090 Phage tail tape measure protein MKLM6_RS05270 c170ef416cbdc9a374ba7a9f0ef163a5 536 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 237 377 5.6E-10 T 28-03-2018 IPR010090 Phage tail tape measure protein MKLM6_RS12915 898d6b8fcfc1c1127d3ef5627ec33fd9 464 Gene3D G3DSA:1.20.1600.10 11 464 8.0E-46 T 28-03-2018 MKLM6_RS12915 898d6b8fcfc1c1127d3ef5627ec33fd9 464 SUPERFAMILY SSF56954 104 456 4.36E-42 T 28-03-2018 MKLM6_RS12915 898d6b8fcfc1c1127d3ef5627ec33fd9 464 SUPERFAMILY SSF56954 2 75 4.36E-42 T 28-03-2018 MKLM6_RS12915 898d6b8fcfc1c1127d3ef5627ec33fd9 464 Pfam PF02321 Outer membrane efflux protein 24 243 1.1E-12 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS12915 898d6b8fcfc1c1127d3ef5627ec33fd9 464 Pfam PF02321 Outer membrane efflux protein 275 426 5.6E-14 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS04845 1e21144a1ce700b68475c50089f27d13 266 Pfam PF01578 Cytochrome C assembly protein 46 262 9.5E-33 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 MKLM6_RS09890 ce1282a7334104bb171ba9d072e0244b 212 Pfam PF09618 CRISPR-associated protein (Cas_Csy4) 4 212 8.0E-60 T 28-03-2018 IPR013396 CRISPR-associated endoribonuclease Cas6/Csy4, subtype I-F/YPEST GO:0004519|GO:0043571 MKLM6_RS09890 ce1282a7334104bb171ba9d072e0244b 212 TIGRFAM TIGR02563 cas_Csy4: CRISPR-associated endoribonuclease Cas6/Csy4, subtype I-F/YPEST 165 212 1.0E-10 T 28-03-2018 IPR013396 CRISPR-associated endoribonuclease Cas6/Csy4, subtype I-F/YPEST GO:0004519|GO:0043571 MKLM6_RS09890 ce1282a7334104bb171ba9d072e0244b 212 TIGRFAM TIGR02563 cas_Csy4: CRISPR-associated endoribonuclease Cas6/Csy4, subtype I-F/YPEST 3 130 2.5E-22 T 28-03-2018 IPR013396 CRISPR-associated endoribonuclease Cas6/Csy4, subtype I-F/YPEST GO:0004519|GO:0043571 MKLM6_RS15120 b62434c0f458de7b9c82884a80b39cc5 87 Pfam PF03658 RnfH family Ubiquitin 1 83 4.0E-34 T 28-03-2018 IPR005346 RnfH protein MKLM6_RS15120 b62434c0f458de7b9c82884a80b39cc5 87 Hamap MF_00460 Protein RnfH [rnfH]. 1 87 23.675 T 28-03-2018 IPR005346 RnfH protein MKLM6_RS15120 b62434c0f458de7b9c82884a80b39cc5 87 Gene3D G3DSA:3.10.20.280 1 85 5.7E-32 T 28-03-2018 IPR005346 RnfH protein MKLM6_RS15120 b62434c0f458de7b9c82884a80b39cc5 87 SUPERFAMILY SSF54285 1 74 9.81E-26 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MKLM6_RS22190 a931e3f61c3f592d471aca0479edcc06 256 Pfam PF14460 Prokaryotic E2 family D 78 243 1.0E-29 T 28-03-2018 IPR032787 Prokaryotic E2 family D MKLM6_RS22190 a931e3f61c3f592d471aca0479edcc06 256 TIGRFAM TIGR03737 PRTRC_B: PRTRC system protein B 39 254 1.1E-46 T 28-03-2018 IPR022280 ParB-related, ThiF-related cassette, protein B MKLM6_RS09070 3f8e063d4e8385e852a9196e0a64ffac 289 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 9 274 1.4E-58 T 28-03-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 MKLM6_RS10890 03abab5efbd0ae496139e200d2fb28f8 648 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 313 328 3.6E-59 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10890 03abab5efbd0ae496139e200d2fb28f8 648 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 628 641 3.6E-59 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10890 03abab5efbd0ae496139e200d2fb28f8 648 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 3.6E-59 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10890 03abab5efbd0ae496139e200d2fb28f8 648 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 351 368 3.6E-59 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10890 03abab5efbd0ae496139e200d2fb28f8 648 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 3.6E-59 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10890 03abab5efbd0ae496139e200d2fb28f8 648 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 189 204 3.6E-59 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10890 03abab5efbd0ae496139e200d2fb28f8 648 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 394 413 3.6E-59 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10890 03abab5efbd0ae496139e200d2fb28f8 648 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 53 638 2.6E-234 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10890 03abab5efbd0ae496139e200d2fb28f8 648 Pfam PF01578 Cytochrome C assembly protein 89 295 1.2E-55 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 MKLM6_RS10890 03abab5efbd0ae496139e200d2fb28f8 648 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 315 635 2.2E-125 T 28-03-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal MKLM6_RS10890 03abab5efbd0ae496139e200d2fb28f8 648 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 310 329 3.3E-94 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10890 03abab5efbd0ae496139e200d2fb28f8 648 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 210 236 3.3E-94 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10890 03abab5efbd0ae496139e200d2fb28f8 648 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 294 310 3.3E-94 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10890 03abab5efbd0ae496139e200d2fb28f8 648 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 159 181 3.3E-94 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10890 03abab5efbd0ae496139e200d2fb28f8 648 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 274 294 3.3E-94 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10890 03abab5efbd0ae496139e200d2fb28f8 648 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 3.3E-94 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10890 03abab5efbd0ae496139e200d2fb28f8 648 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 244 264 3.3E-94 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10890 03abab5efbd0ae496139e200d2fb28f8 648 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 3.3E-94 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS05360 c82748ec574e84616047c294e9e41ab4 247 Pfam PF03692 Putative zinc- or iron-chelating domain 62 169 3.9E-8 T 28-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein MKLM6_RS17700 0496efed48beea8581734220b48c8e70 279 SUPERFAMILY SSF52540 5 230 2.18E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS17700 0496efed48beea8581734220b48c8e70 279 Gene3D G3DSA:3.40.50.300 1 264 1.9E-60 T 28-03-2018 MKLM6_RS17700 0496efed48beea8581734220b48c8e70 279 Pfam PF00005 ABC transporter 25 171 1.4E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS17700 0496efed48beea8581734220b48c8e70 279 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS17700 0496efed48beea8581734220b48c8e70 279 SMART SM00382 34 222 3.0E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS21755 2a3c3671fa46e7cc214c38a9a9184f6d 484 Pfam PF11855 Protein of unknown function (DUF3375) 13 482 8.3E-160 T 28-03-2018 IPR021804 Protein of unknown function DUF3375 MKLM6_RS10645 ca0a6b991622f21071e3a407f6f13f50 313 PIRSF PIRSF005427 1 313 2.7E-73 T 28-03-2018 IPR005588 MucB/RseB MKLM6_RS10645 ca0a6b991622f21071e3a407f6f13f50 313 Gene3D G3DSA:2.50.20.10 15 263 3.2E-18 T 28-03-2018 MKLM6_RS10645 ca0a6b991622f21071e3a407f6f13f50 313 Pfam PF03888 MucB/RseB N-terminal domain 23 189 3.3E-51 T 28-03-2018 IPR033434 MucB/RseB, N-terminal MKLM6_RS10645 ca0a6b991622f21071e3a407f6f13f50 313 Pfam PF17188 MucB/RseB C-terminal domain 217 309 9.1E-21 T 28-03-2018 IPR033436 MucB/RseB, C-terminal MKLM6_RS09405 e44631b4c4dbe64a80bc1ded2d2b061a 72 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 37 69 9.4E-12 T 28-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 MKLM6_RS09405 e44631b4c4dbe64a80bc1ded2d2b061a 72 SUPERFAMILY SSF57716 39 70 1.3E-5 T 28-03-2018 MKLM6_RS11355 8b11e85012fef3a1fdbfe24b5a1bdb0b 221 SUPERFAMILY SSF54523 128 189 1.05E-7 T 28-03-2018 MKLM6_RS20495 0b5a08547979684f475fe79005c3f06a 575 SUPERFAMILY SSF56601 182 568 1.47E-93 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MKLM6_RS20495 0b5a08547979684f475fe79005c3f06a 575 Pfam PF00905 Penicillin binding protein transpeptidase domain 257 551 1.4E-75 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MKLM6_RS20495 0b5a08547979684f475fe79005c3f06a 575 SUPERFAMILY SSF56519 58 231 1.57E-44 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MKLM6_RS20495 0b5a08547979684f475fe79005c3f06a 575 Gene3D G3DSA:3.90.1310.10 33 231 1.5E-46 T 28-03-2018 MKLM6_RS20495 0b5a08547979684f475fe79005c3f06a 575 Pfam PF03717 Penicillin-binding Protein dimerisation domain 65 216 1.9E-23 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MKLM6_RS20495 0b5a08547979684f475fe79005c3f06a 575 Gene3D G3DSA:3.40.710.10 232 569 2.1E-85 T 28-03-2018 MKLM6_RS18400 27d26d4db9ceac031a5f9aabbb5c355a 63 Pfam PF00831 Ribosomal L29 protein 5 59 6.3E-24 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18400 27d26d4db9ceac031a5f9aabbb5c355a 63 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 59 2.4E-23 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18400 27d26d4db9ceac031a5f9aabbb5c355a 63 SUPERFAMILY SSF46561 1 60 4.84E-21 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18400 27d26d4db9ceac031a5f9aabbb5c355a 63 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 28-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18400 27d26d4db9ceac031a5f9aabbb5c355a 63 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 17.434 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MKLM6_RS18400 27d26d4db9ceac031a5f9aabbb5c355a 63 Gene3D G3DSA:1.10.287.310 1 63 6.0E-24 T 28-03-2018 MKLM6_RS20285 e6816f58fa114b0c1810eacba3227409 160 Gene3D G3DSA:2.30.110.20 1 160 1.8E-39 T 28-03-2018 IPR008514 Type VI secretion system effector, Hcp MKLM6_RS20285 e6816f58fa114b0c1810eacba3227409 160 Pfam PF05638 Type VI secretion system effector, Hcp 8 135 1.8E-29 T 28-03-2018 IPR008514 Type VI secretion system effector, Hcp MKLM6_RS20285 e6816f58fa114b0c1810eacba3227409 160 SUPERFAMILY SSF141452 8 159 3.01E-33 T 28-03-2018 IPR008514 Type VI secretion system effector, Hcp MKLM6_RS12480 42cb2e6f89f6506b9db34f84df2f959f 319 PIRSF PIRSF004884 4 319 1.4E-84 T 28-03-2018 IPR004422 GHMP kinase group 1 MetaCyc: PWY-6148 MKLM6_RS12480 42cb2e6f89f6506b9db34f84df2f959f 319 SUPERFAMILY SSF54211 8 152 4.55E-22 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS12480 42cb2e6f89f6506b9db34f84df2f959f 319 Gene3D G3DSA:3.30.230.10 6 155 9.9E-17 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MKLM6_RS12480 42cb2e6f89f6506b9db34f84df2f959f 319 Pfam PF00288 GHMP kinases N terminal domain 81 134 1.9E-7 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 MKLM6_RS12480 42cb2e6f89f6506b9db34f84df2f959f 319 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 10 312 1.7E-49 T 28-03-2018 IPR004422 GHMP kinase group 1 MetaCyc: PWY-6148 MKLM6_RS12480 42cb2e6f89f6506b9db34f84df2f959f 319 Gene3D G3DSA:3.30.70.890 165 318 5.8E-10 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain MKLM6_RS18685 63896864adc18f9634e1422be8918f85 425 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 7 229 5.1E-59 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 MKLM6_RS18685 63896864adc18f9634e1422be8918f85 425 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 116 129 1.4E-10 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MKLM6_RS18685 63896864adc18f9634e1422be8918f85 425 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 36 47 1.4E-10 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MKLM6_RS18685 63896864adc18f9634e1422be8918f85 425 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 89 106 1.4E-10 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MKLM6_RS18685 63896864adc18f9634e1422be8918f85 425 Gene3D G3DSA:3.40.710.10 2 266 1.6E-50 T 28-03-2018 MKLM6_RS18685 63896864adc18f9634e1422be8918f85 425 SUPERFAMILY SSF56601 5 247 3.54E-72 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MKLM6_RS17805 92b09e9ac333d1af995ab0d604c92e95 90 Pfam PF04319 NifZ domain 7 79 3.4E-15 T 28-03-2018 IPR007415 Nitrogenase MoFe maturation protein, NifZ GO:0009399 MKLM6_RS22120 4856d1828dbbb128737cc97a16b47331 108 SUPERFAMILY SSF54909 4 104 1.61E-15 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel MKLM6_RS22120 4856d1828dbbb128737cc97a16b47331 108 Pfam PF07110 EthD domain 15 84 8.7E-6 T 28-03-2018 IPR009799 EthD domain MKLM6_RS22120 4856d1828dbbb128737cc97a16b47331 108 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 4 105 5.6E-16 T 28-03-2018 IPR009799 EthD domain MKLM6_RS22120 4856d1828dbbb128737cc97a16b47331 108 Gene3D G3DSA:3.30.70.100 4 102 2.6E-14 T 28-03-2018 MKLM6_RS10940 bc0435d0e7c82df4edcf27a8db7b9a03 470 Pfam PF12679 ABC-2 family transporter protein 4 269 3.4E-25 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 MKLM6_RS10940 bc0435d0e7c82df4edcf27a8db7b9a03 470 Pfam PF12040 Domain of unknown function (DUF3526) 276 432 1.8E-35 T 28-03-2018 IPR021913 Protein of unknown function DUF3526 MKLM6_RS07120 311505d18635cd4111dd16bc09aa82a0 370 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 10 357 2.5E-141 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MKLM6_RS07120 311505d18635cd4111dd16bc09aa82a0 370 Pfam PF04055 Radical SAM superfamily 116 281 2.9E-20 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS07120 311505d18635cd4111dd16bc09aa82a0 370 SUPERFAMILY SSF102114 112 308 5.36E-18 T 28-03-2018 MKLM6_RS07120 311505d18635cd4111dd16bc09aa82a0 370 PIRSF PIRSF006004 7 366 6.2E-151 T 28-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MKLM6_RS07120 311505d18635cd4111dd16bc09aa82a0 370 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 12 353 73.447 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MKLM6_RS07120 311505d18635cd4111dd16bc09aa82a0 370 Gene3D G3DSA:3.20.20.70 23 357 1.3E-42 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS12950 3ee786d7b1e87da7cf5d62a68e868c1e 186 Gene3D G3DSA:3.90.1570.10 2 186 3.8E-23 T 28-03-2018 MKLM6_RS12950 3ee786d7b1e87da7cf5d62a68e868c1e 186 SUPERFAMILY SSF52980 13 158 2.79E-12 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MKLM6_RS12950 3ee786d7b1e87da7cf5d62a68e868c1e 186 Pfam PF05685 Putative restriction endonuclease 18 179 9.6E-24 T 28-03-2018 IPR008538 Domain of unknown function DUF820 MKLM6_RS10040 10caac4d8c2d87b52f755dda03f740fe 54 Pfam PF07896 Protein of unknown function (DUF1674) 19 54 1.3E-15 T 28-03-2018 IPR012875 Protein of unknown function DUF1674 MKLM6_RS04020 330ba39be82c6b471bdcde453e4c1468 390 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 6 388 39.263 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS04020 330ba39be82c6b471bdcde453e4c1468 390 Gene3D G3DSA:3.40.50.1260 3 174 1.7E-59 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS04020 330ba39be82c6b471bdcde453e4c1468 390 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 28-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS04020 330ba39be82c6b471bdcde453e4c1468 390 SUPERFAMILY SSF53748 3 387 1.41E-145 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS04020 330ba39be82c6b471bdcde453e4c1468 390 Gene3D G3DSA:3.40.50.1260 175 376 2.3E-81 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS04020 330ba39be82c6b471bdcde453e4c1468 390 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 7.1E-78 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS04020 330ba39be82c6b471bdcde453e4c1468 390 PRINTS PR00477 Phosphoglycerate kinase family signature 186 205 7.1E-78 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS04020 330ba39be82c6b471bdcde453e4c1468 390 PRINTS PR00477 Phosphoglycerate kinase family signature 163 185 7.1E-78 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS04020 330ba39be82c6b471bdcde453e4c1468 390 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 7.1E-78 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS04020 330ba39be82c6b471bdcde453e4c1468 390 PRINTS PR00477 Phosphoglycerate kinase family signature 132 154 7.1E-78 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS04020 330ba39be82c6b471bdcde453e4c1468 390 PRINTS PR00477 Phosphoglycerate kinase family signature 104 119 7.1E-78 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS04020 330ba39be82c6b471bdcde453e4c1468 390 PRINTS PR00477 Phosphoglycerate kinase family signature 364 381 7.1E-78 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS04020 330ba39be82c6b471bdcde453e4c1468 390 PRINTS PR00477 Phosphoglycerate kinase family signature 308 333 7.1E-78 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS04020 330ba39be82c6b471bdcde453e4c1468 390 PRINTS PR00477 Phosphoglycerate kinase family signature 341 352 7.1E-78 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS04020 330ba39be82c6b471bdcde453e4c1468 390 Pfam PF00162 Phosphoglycerate kinase 7 378 1.7E-143 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS04020 330ba39be82c6b471bdcde453e4c1468 390 PIRSF PIRSF000724 1 390 1.9E-135 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MKLM6_RS08280 f85ed661bcc17c7f37404d74aad29f88 398 SUPERFAMILY SSF56801 92 388 9.81E-35 T 28-03-2018 MKLM6_RS08280 f85ed661bcc17c7f37404d74aad29f88 398 Gene3D G3DSA:3.40.50.980 97 262 6.9E-17 T 28-03-2018 MKLM6_RS08280 f85ed661bcc17c7f37404d74aad29f88 398 Pfam PF00501 AMP-binding enzyme 89 251 2.9E-10 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MKLM6_RS08280 f85ed661bcc17c7f37404d74aad29f88 398 Gene3D G3DSA:3.30.300.30 302 393 2.1E-14 T 28-03-2018 MKLM6_RS08085 b29b5e4652f1c90d2b83722c26968475 540 Gene3D G3DSA:3.40.720.10 221 507 8.2E-18 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MKLM6_RS08085 b29b5e4652f1c90d2b83722c26968475 540 Pfam PF00884 Sulfatase 233 477 7.7E-9 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 MKLM6_RS08085 b29b5e4652f1c90d2b83722c26968475 540 SUPERFAMILY SSF53649 229 412 1.94E-15 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MKLM6_RS08085 b29b5e4652f1c90d2b83722c26968475 540 SUPERFAMILY SSF53649 439 515 1.94E-15 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MKLM6_RS13010 a9f4d10026bbe2c792f20dc4a9a46f96 692 Gene3D G3DSA:3.30.1120.10 615 692 4.1E-8 T 28-03-2018 MKLM6_RS13010 a9f4d10026bbe2c792f20dc4a9a46f96 692 SUPERFAMILY SSF53649 627 682 1.16E-79 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MKLM6_RS13010 a9f4d10026bbe2c792f20dc4a9a46f96 692 SUPERFAMILY SSF53649 204 583 1.16E-79 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MKLM6_RS13010 a9f4d10026bbe2c792f20dc4a9a46f96 692 Pfam PF00884 Sulfatase 207 550 1.0E-45 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 MKLM6_RS13010 a9f4d10026bbe2c792f20dc4a9a46f96 692 Gene3D G3DSA:3.40.720.10 207 569 8.0E-64 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MKLM6_RS18610 9d030ff773f8887d4e96bfd8f8fc1d89 283 SUPERFAMILY SSF109604 10 272 3.77E-60 T 28-03-2018 MKLM6_RS18610 9d030ff773f8887d4e96bfd8f8fc1d89 283 Pfam PF08668 HDOD domain 21 218 3.4E-52 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD MKLM6_RS18610 9d030ff773f8887d4e96bfd8f8fc1d89 283 Gene3D G3DSA:1.10.3210.10 3 271 5.4E-39 T 28-03-2018 MKLM6_RS14605 dc6e221c4bd2fcf979629f3bffb9a968 260 Pfam PF04333 MlaA lipoprotein 29 229 4.3E-72 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 MKLM6_RS14605 dc6e221c4bd2fcf979629f3bffb9a968 260 PRINTS PR01805 VacJ lipoprotein signature 47 63 1.2E-26 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 MKLM6_RS14605 dc6e221c4bd2fcf979629f3bffb9a968 260 PRINTS PR01805 VacJ lipoprotein signature 98 115 1.2E-26 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 MKLM6_RS14605 dc6e221c4bd2fcf979629f3bffb9a968 260 PRINTS PR01805 VacJ lipoprotein signature 134 151 1.2E-26 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 MKLM6_RS14605 dc6e221c4bd2fcf979629f3bffb9a968 260 PRINTS PR01805 VacJ lipoprotein signature 30 43 1.2E-26 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 MKLM6_RS07865 7c0ad80505e538fc95cc481662bd38a9 282 Pfam PF07589 PEP-CTERM motif 225 245 1.7E-4 T 28-03-2018 IPR013424 PEP-CTERM protein-sorting domain MKLM6_RS07865 7c0ad80505e538fc95cc481662bd38a9 282 Gene3D G3DSA:2.60.120.380 49 181 9.5E-10 T 28-03-2018 MKLM6_RS20090 8cd060ab56179ab3f597064350075b0a 373 Pfam PF03527 RHS protein 122 153 6.7E-9 T 28-03-2018 IPR001826 RHS protein MKLM6_RS20090 8cd060ab56179ab3f597064350075b0a 373 PRINTS PR00394 RHS protein signature 169 189 6.2E-12 T 28-03-2018 IPR001826 RHS protein MKLM6_RS20090 8cd060ab56179ab3f597064350075b0a 373 PRINTS PR00394 RHS protein signature 192 211 6.2E-12 T 28-03-2018 IPR001826 RHS protein MKLM6_RS20090 8cd060ab56179ab3f597064350075b0a 373 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 150 225 1.3E-29 T 28-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 MKLM6_RS11760 df402fdba082641c8737098e20cbf39a 287 SMART SM00244 21 184 5.2E-32 T 28-03-2018 IPR001107 Band 7 domain MKLM6_RS11760 df402fdba082641c8737098e20cbf39a 287 Pfam PF01145 SPFH domain / Band 7 family 26 199 8.1E-29 T 28-03-2018 IPR001107 Band 7 domain MKLM6_RS11760 df402fdba082641c8737098e20cbf39a 287 PIRSF PIRSF005651 1 287 5.1E-96 T 28-03-2018 IPR010200 HflC GO:0016021|GO:0052547 MKLM6_RS11760 df402fdba082641c8737098e20cbf39a 287 SUPERFAMILY SSF117892 54 190 8.11E-29 T 28-03-2018 IPR001107 Band 7 domain MKLM6_RS11760 df402fdba082641c8737098e20cbf39a 287 PRINTS PR00721 Stomatin signature 179 200 2.3E-9 T 28-03-2018 IPR001972 Stomatin family GO:0016020 MKLM6_RS11760 df402fdba082641c8737098e20cbf39a 287 PRINTS PR00721 Stomatin signature 28 50 2.3E-9 T 28-03-2018 IPR001972 Stomatin family GO:0016020 MKLM6_RS11760 df402fdba082641c8737098e20cbf39a 287 PRINTS PR00721 Stomatin signature 76 97 2.3E-9 T 28-03-2018 IPR001972 Stomatin family GO:0016020 MKLM6_RS11760 df402fdba082641c8737098e20cbf39a 287 PRINTS PR00721 Stomatin signature 160 178 2.3E-9 T 28-03-2018 IPR001972 Stomatin family GO:0016020 MKLM6_RS11760 df402fdba082641c8737098e20cbf39a 287 TIGRFAM TIGR01932 hflC: HflC protein 155 283 9.2E-49 T 28-03-2018 IPR010200 HflC GO:0016021|GO:0052547 MKLM6_RS03225 dc8c9e714a10f7e5c5d3274def9f3813 135 SUPERFAMILY SSF48403 58 133 1.13E-12 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain MKLM6_RS03225 dc8c9e714a10f7e5c5d3274def9f3813 135 Pfam PF12796 Ankyrin repeats (3 copies) 56 133 5.8E-8 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain MKLM6_RS03225 dc8c9e714a10f7e5c5d3274def9f3813 135 Gene3D G3DSA:1.20.120.660 29 134 1.5E-15 T 28-03-2018 MKLM6_RS03225 dc8c9e714a10f7e5c5d3274def9f3813 135 SMART SM00248 49 80 460.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 MKLM6_RS03225 dc8c9e714a10f7e5c5d3274def9f3813 135 SMART SM00248 81 110 1.6 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 MKLM6_RS02785 99faebfba30dddb18ac413ff20c9a1a4 248 Pfam PF01618 MotA/TolQ/ExbB proton channel family 101 219 1.9E-26 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 MKLM6_RS01490 18e509c9c546832f21c159ed93c0b4a9 332 Gene3D G3DSA:1.20.970.10 2 97 6.6E-24 T 28-03-2018 MKLM6_RS01490 18e509c9c546832f21c159ed93c0b4a9 332 Pfam PF00591 Glycosyl transferase family, a/b domain 106 322 7.8E-9 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MKLM6_RS01490 18e509c9c546832f21c159ed93c0b4a9 332 Gene3D G3DSA:3.40.1030.10 98 328 4.7E-46 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MKLM6_RS01490 18e509c9c546832f21c159ed93c0b4a9 332 Pfam PF02885 Glycosyl transferase family, helical bundle domain 14 77 3.2E-15 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 MKLM6_RS01490 18e509c9c546832f21c159ed93c0b4a9 332 SUPERFAMILY SSF52418 84 327 3.79E-60 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MKLM6_RS01490 18e509c9c546832f21c159ed93c0b4a9 332 SUPERFAMILY SSF47648 16 78 4.71E-14 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 MKLM6_RS13225 2e19cc084f8504a4bb0ea6365cea2437 239 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 237 43.002 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 MKLM6_RS13225 2e19cc084f8504a4bb0ea6365cea2437 239 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 7 236 8.8E-93 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 MKLM6_RS13225 2e19cc084f8504a4bb0ea6365cea2437 239 Pfam PF00696 Amino acid kinase family 8 216 3.3E-28 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MKLM6_RS13225 2e19cc084f8504a4bb0ea6365cea2437 239 SUPERFAMILY SSF53633 5 237 1.28E-70 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MKLM6_RS13225 2e19cc084f8504a4bb0ea6365cea2437 239 PIRSF PIRSF005650 1 239 1.2E-87 T 28-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 MKLM6_RS13225 2e19cc084f8504a4bb0ea6365cea2437 239 Gene3D G3DSA:3.40.1160.10 2 238 5.2E-45 T 28-03-2018 MKLM6_RS07280 6640fbcae6fa0569623807e71808a1e8 123 ProDom PD339292 LIPID A SYNTHASE LIPID-A-DISACCHARIDE TRANSFERASE GLYCOSYLTRANSFERASE BIOSYNTHESIS N-TERMINAL BIOSYNTHESIS SYNTHESIS 30 105 7.0E-22 T 28-03-2018 IPR011499 Lipid A biosynthesis, N-terminal GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 MKLM6_RS07280 6640fbcae6fa0569623807e71808a1e8 123 Pfam PF07578 Lipid A Biosynthesis N-terminal domain 33 103 1.3E-31 T 28-03-2018 IPR011499 Lipid A biosynthesis, N-terminal GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 MKLM6_RS07280 6640fbcae6fa0569623807e71808a1e8 123 SMART SM01259 33 104 7.1E-42 T 28-03-2018 IPR011499 Lipid A biosynthesis, N-terminal GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 MKLM6_RS05535 0f037ffea9ca038a00e62e43c2d20973 662 Pfam PF00593 TonB dependent receptor 253 659 8.3E-50 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS05535 0f037ffea9ca038a00e62e43c2d20973 662 SUPERFAMILY SSF56935 52 662 1.98E-106 T 28-03-2018 MKLM6_RS05535 0f037ffea9ca038a00e62e43c2d20973 662 Gene3D G3DSA:2.170.130.10 46 181 9.0E-25 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS05535 0f037ffea9ca038a00e62e43c2d20973 662 Pfam PF07715 TonB-dependent Receptor Plug Domain 62 171 1.5E-20 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS05535 0f037ffea9ca038a00e62e43c2d20973 662 Gene3D G3DSA:2.40.170.20 182 662 7.2E-71 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS14520 143e3f98dc51f7501b2fdb0bd86ca40d 869 Hamap MF_01871 UPF0753 protein . 26 826 20.048 T 28-03-2018 IPR018752 Uncharacterised protein family UPF0753 MKLM6_RS14520 143e3f98dc51f7501b2fdb0bd86ca40d 869 Pfam PF10070 Uncharacterized protein conserved in bacteria (DUF2309) 31 811 2.3E-235 T 28-03-2018 IPR018752 Uncharacterised protein family UPF0753 MKLM6_RS17965 0ab4d11429e5c6e07c8161512260754e 122 Pfam PF00825 Ribonuclease P 8 114 2.7E-26 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 MKLM6_RS17965 0ab4d11429e5c6e07c8161512260754e 122 SUPERFAMILY SSF54211 8 116 1.59E-25 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS17965 0ab4d11429e5c6e07c8161512260754e 122 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 58 72 - T 28-03-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 MKLM6_RS17965 0ab4d11429e5c6e07c8161512260754e 122 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 8 117 16.648 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 MKLM6_RS17965 0ab4d11429e5c6e07c8161512260754e 122 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 15 114 5.6E-21 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 MKLM6_RS17965 0ab4d11429e5c6e07c8161512260754e 122 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 20 105 6.0E-12 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 MKLM6_RS17965 0ab4d11429e5c6e07c8161512260754e 122 Gene3D G3DSA:3.30.230.10 3 121 2.1E-26 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MKLM6_RS11695 278523cbb482399a4cd74cb5764d3722 63 SUPERFAMILY SSF54786 1 61 1.26E-16 T 28-03-2018 MKLM6_RS11695 278523cbb482399a4cd74cb5764d3722 63 Gene3D G3DSA:3.30.920.30 1 60 6.4E-20 T 28-03-2018 MKLM6_RS11695 278523cbb482399a4cd74cb5764d3722 63 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 3 60 4.9E-20 T 28-03-2018 IPR012933 HicA mRNA interferase family GO:0003729 MKLM6_RS22355 16a1883d3489331b36280361546169e7 470 PIRSF PIRSF500217 1 470 2.8E-132 T 28-03-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 MKLM6_RS22355 16a1883d3489331b36280361546169e7 470 PIRSF PIRSF016636 1 470 3.5E-133 T 28-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB MKLM6_RS22355 16a1883d3489331b36280361546169e7 470 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 152 370 1.9E-24 T 28-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT MKLM6_RS08710 b91c8c261402da1ad0b7f8842d061172 87 Pfam PF11137 Protein of unknown function (DUF2909) 3 64 1.9E-20 T 28-03-2018 IPR021313 Protein of unknown function DUF2909 MKLM6_RS11605 887f7159e2024b7d9c2a2cc08b4f6928 316 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 190 227 2.4E-12 T 28-03-2018 IPR011964 YVTN beta-propeller repeat MKLM6_RS11605 887f7159e2024b7d9c2a2cc08b4f6928 316 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 272 305 2.6E-13 T 28-03-2018 IPR011964 YVTN beta-propeller repeat MKLM6_RS11605 887f7159e2024b7d9c2a2cc08b4f6928 316 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 24 61 5.2E-12 T 28-03-2018 IPR011964 YVTN beta-propeller repeat MKLM6_RS11605 887f7159e2024b7d9c2a2cc08b4f6928 316 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 233 268 1.6E-12 T 28-03-2018 IPR011964 YVTN beta-propeller repeat MKLM6_RS11605 887f7159e2024b7d9c2a2cc08b4f6928 316 Pfam PF10282 Lactonase, 7-bladed beta-propeller 134 206 6.8E-10 T 28-03-2018 IPR019405 Lactonase, 7-bladed beta propeller MKLM6_RS11605 887f7159e2024b7d9c2a2cc08b4f6928 316 Gene3D G3DSA:2.130.10.10 21 100 3.9E-10 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MKLM6_RS11605 887f7159e2024b7d9c2a2cc08b4f6928 316 Gene3D G3DSA:2.130.10.10 200 312 2.8E-28 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MKLM6_RS11605 887f7159e2024b7d9c2a2cc08b4f6928 316 Gene3D G3DSA:2.130.10.10 101 199 8.2E-25 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MKLM6_RS11605 887f7159e2024b7d9c2a2cc08b4f6928 316 SUPERFAMILY SSF51004 16 308 1.49E-70 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain MKLM6_RS02230 9069aa9fc8d6e78d96a011341bd2079d 191 Pfam PF06804 NlpB/DapX lipoprotein 62 143 1.1E-5 T 28-03-2018 IPR010653 NlpB/DapX lipoprotein MKLM6_RS20110 b8d44f8ad84211ed7335c685e4236939 184 SUPERFAMILY SSF54001 39 168 4.58E-40 T 28-03-2018 MKLM6_RS20110 b8d44f8ad84211ed7335c685e4236939 184 Gene3D G3DSA:3.90.1720.10 42 178 3.3E-37 T 28-03-2018 MKLM6_RS20110 b8d44f8ad84211ed7335c685e4236939 184 Pfam PF00877 NlpC/P60 family 59 165 1.1E-28 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain MKLM6_RS10075 401853a6d699775e48916dc207c86e9a 154 SUPERFAMILY SSF54523 7 140 3.77E-25 T 28-03-2018 MKLM6_RS10075 401853a6d699775e48916dc207c86e9a 154 Gene3D G3DSA:3.30.700.10 7 151 2.9E-27 T 28-03-2018 MKLM6_RS10075 401853a6d699775e48916dc207c86e9a 154 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 26 2.4E-9 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS10075 401853a6d699775e48916dc207c86e9a 154 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 27 1.6E-8 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS10075 401853a6d699775e48916dc207c86e9a 154 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 28 131 2.8E-23 T 28-03-2018 IPR031982 Type IV minor pilin ComP MKLM6_RS06345 4a7a39677b3dc79b9ab60040ba8c077b 543 Pfam PF05425 Copper resistance protein D 197 297 4.0E-13 T 28-03-2018 IPR008457 Copper resistance protein D GO:0016021 MKLM6_RS22095 3e5f8ecbb80d5a6bfd72d6da4c61f7bd 112 Gene3D G3DSA:2.30.30.110 2 111 4.2E-26 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor MKLM6_RS22095 3e5f8ecbb80d5a6bfd72d6da4c61f7bd 112 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 8 110 7.1E-23 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 MKLM6_RS22095 3e5f8ecbb80d5a6bfd72d6da4c61f7bd 112 SUPERFAMILY SSF50118 4 111 3.71E-32 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor MKLM6_RS13845 b17385aba11157299c78faedb248f150 305 SUPERFAMILY SSF53335 27 281 1.58E-54 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS13845 b17385aba11157299c78faedb248f150 305 Pfam PF08241 Methyltransferase domain 90 188 5.8E-24 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MKLM6_RS13845 b17385aba11157299c78faedb248f150 305 Gene3D G3DSA:3.40.50.150 4 288 3.8E-43 T 28-03-2018 MKLM6_RS13845 b17385aba11157299c78faedb248f150 305 SMART SM00828 Methyltransferase in polyketide synthase (PKS) enzymes. 60 299 0.0033 T 28-03-2018 IPR020803 Polyketide synthase, methyltransferase domain MKLM6_RS07720 690decf6608b0b453d1c7b17a4f50c19 336 Pfam PF01148 Cytidylyltransferase family 83 334 1.0E-45 T 28-03-2018 MKLM6_RS22315 a150a5ff596c6115a749ecbddd1d894e 699 TIGRFAM TIGR02688 TIGR02688: TIGR02688 family protein 8 458 2.2E-189 T 28-03-2018 IPR014061 Conserved hypothetical protein CHP02688 MKLM6_RS22315 a150a5ff596c6115a749ecbddd1d894e 699 Pfam PF13337 Putative ATP-dependent Lon protease 11 466 1.9E-180 T 28-03-2018 IPR014061 Conserved hypothetical protein CHP02688 MKLM6_RS22315 a150a5ff596c6115a749ecbddd1d894e 699 Pfam PF16565 Phospholipase D-like domain at C-terminus of MIT 541 687 9.9E-46 T 28-03-2018 IPR032341 MIT, C-terminal phospholipase D-like domain MKLM6_RS16100 3b7b066d2047dedfaabf52361d0e3975 461 Pfam PF13175 AAA ATPase domain 305 388 8.3E-9 T 28-03-2018 MKLM6_RS16100 3b7b066d2047dedfaabf52361d0e3975 461 Gene3D G3DSA:3.40.50.300 303 409 1.2E-5 T 28-03-2018 MKLM6_RS05055 eba9c402b9784da78db00f790a5f6496 369 Pfam PF07995 Glucose / Sorbosone dehydrogenase 136 357 3.2E-13 T 28-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase MKLM6_RS05055 eba9c402b9784da78db00f790a5f6496 369 SUPERFAMILY SSF50952 28 368 9.02E-31 T 28-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 MKLM6_RS05055 eba9c402b9784da78db00f790a5f6496 369 Gene3D G3DSA:2.120.10.30 256 369 1.8E-14 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MKLM6_RS05055 eba9c402b9784da78db00f790a5f6496 369 Gene3D G3DSA:2.120.10.30 22 255 1.0E-26 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MKLM6_RS03490 a3676f58161c32b710630808c2c44de5 159 SUPERFAMILY SSF47175 52 156 3.24E-8 T 28-03-2018 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 MKLM6_RS03490 a3676f58161c32b710630808c2c44de5 159 Pfam PF01322 Cytochrome C' 106 155 4.1E-5 T 28-03-2018 IPR002321 Cytochrome c, class II GO:0005506|GO:0009055|GO:0020037 MKLM6_RS03490 a3676f58161c32b710630808c2c44de5 159 Gene3D G3DSA:1.20.120.10 38 157 1.1E-10 T 28-03-2018 MKLM6_RS01050 b65c57e1c5416ad78b56da1b80bae453 561 Gene3D G3DSA:3.20.20.80 103 422 3.4E-18 T 28-03-2018 MKLM6_RS01050 b65c57e1c5416ad78b56da1b80bae453 561 Gene3D G3DSA:2.60.40.1500 423 561 8.8E-8 T 28-03-2018 MKLM6_RS01050 b65c57e1c5416ad78b56da1b80bae453 561 SUPERFAMILY SSF51445 121 428 3.86E-26 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily MKLM6_RS01050 b65c57e1c5416ad78b56da1b80bae453 561 Pfam PF01229 Glycosyl hydrolases family 39 201 511 5.8E-11 T 28-03-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101 MKLM6_RS05975 a630077deca4e8a278b1696535838969 398 Gene3D G3DSA:3.40.50.2000 10 199 6.7E-9 T 28-03-2018 MKLM6_RS05975 a630077deca4e8a278b1696535838969 398 Pfam PF13692 Glycosyl transferases group 1 204 316 4.7E-13 T 28-03-2018 MKLM6_RS05975 a630077deca4e8a278b1696535838969 398 Pfam PF13579 Glycosyl transferase 4-like domain 17 186 2.4E-13 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MKLM6_RS05975 a630077deca4e8a278b1696535838969 398 SUPERFAMILY SSF53756 5 370 1.02E-48 T 28-03-2018 MKLM6_RS05975 a630077deca4e8a278b1696535838969 398 Gene3D G3DSA:3.40.50.2000 200 366 4.8E-24 T 28-03-2018 MKLM6_RS16230 7bb79c45c459395bf52c45149ae1072d 93 SUPERFAMILY SSF48666 23 91 1.05E-35 T 28-03-2018 IPR003420 Methanol dehydrogenase, beta subunit GO:0004022|GO:0015946|GO:0055114 KEGG: 00010+1.1.2.7|KEGG: 00625+1.1.2.7|KEGG: 00680+1.1.2.7|MetaCyc: PWY-6966 MKLM6_RS16230 7bb79c45c459395bf52c45149ae1072d 93 Pfam PF02315 Methanol dehydrogenase beta subunit 7 91 2.4E-43 T 28-03-2018 IPR003420 Methanol dehydrogenase, beta subunit GO:0004022|GO:0015946|GO:0055114 KEGG: 00010+1.1.2.7|KEGG: 00625+1.1.2.7|KEGG: 00680+1.1.2.7|MetaCyc: PWY-6966 MKLM6_RS16230 7bb79c45c459395bf52c45149ae1072d 93 PIRSF PIRSF029163 1 93 1.3E-42 T 28-03-2018 IPR003420 Methanol dehydrogenase, beta subunit GO:0004022|GO:0015946|GO:0055114 KEGG: 00010+1.1.2.7|KEGG: 00625+1.1.2.7|KEGG: 00680+1.1.2.7|MetaCyc: PWY-6966 MKLM6_RS16230 7bb79c45c459395bf52c45149ae1072d 93 Gene3D G3DSA:4.10.160.10 23 92 1.7E-40 T 28-03-2018 IPR003420 Methanol dehydrogenase, beta subunit GO:0004022|GO:0015946|GO:0055114 KEGG: 00010+1.1.2.7|KEGG: 00625+1.1.2.7|KEGG: 00680+1.1.2.7|MetaCyc: PWY-6966 MKLM6_RS15280 aec1d1c5bea0678cd04d0d9cdca70a30 134 Pfam PF03330 Lytic transglycolase 37 125 3.4E-19 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain MKLM6_RS15280 aec1d1c5bea0678cd04d0d9cdca70a30 134 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 39 133 9.8E-38 T 28-03-2018 IPR012997 Rare lipoprotein A MKLM6_RS15280 aec1d1c5bea0678cd04d0d9cdca70a30 134 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 13 129 20.074 T 28-03-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 MKLM6_RS15280 aec1d1c5bea0678cd04d0d9cdca70a30 134 Gene3D G3DSA:2.40.40.10 14 129 2.5E-17 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain MKLM6_RS15280 aec1d1c5bea0678cd04d0d9cdca70a30 134 SUPERFAMILY SSF50685 36 126 1.67E-8 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain MKLM6_RS19945 9efbf2208cebccaf19ce11c8f2a64524 154 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 4 148 1.5E-51 T 28-03-2018 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 MKLM6_RS19945 9efbf2208cebccaf19ce11c8f2a64524 154 Pfam PF02470 MlaD protein 39 118 1.9E-23 T 28-03-2018 IPR003399 Mce/MlaD MKLM6_RS20010 21aa374f3e88572adec986fdaaf3b52e 399 Gene3D G3DSA:1.20.1250.20 8 211 7.6E-26 T 28-03-2018 MKLM6_RS20010 21aa374f3e88572adec986fdaaf3b52e 399 Gene3D G3DSA:1.20.1250.20 212 398 1.0E-22 T 28-03-2018 MKLM6_RS20010 21aa374f3e88572adec986fdaaf3b52e 399 SUPERFAMILY SSF103473 12 393 1.31E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain MKLM6_RS20010 21aa374f3e88572adec986fdaaf3b52e 399 Pfam PF07690 Major Facilitator Superfamily 21 222 6.6E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MKLM6_RS20010 21aa374f3e88572adec986fdaaf3b52e 399 Pfam PF07690 Major Facilitator Superfamily 256 393 9.5E-15 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MKLM6_RS02890 5c348780dee6d9a20170728253cc3755 116 PIRSF PIRSF021239 1 114 2.3E-55 T 28-03-2018 IPR007437 Putative member of DMT superfamily MKLM6_RS02890 5c348780dee6d9a20170728253cc3755 116 Pfam PF04342 Putative member of DMT superfamily (DUF486) 9 111 2.2E-46 T 28-03-2018 IPR007437 Putative member of DMT superfamily MKLM6_RS01775 f89f7052d83ff5fd679471a130732786 225 Pfam PF00034 Cytochrome c 137 225 3.0E-7 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS01775 f89f7052d83ff5fd679471a130732786 225 Gene3D G3DSA:1.10.760.10 13 102 6.8E-23 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS01775 f89f7052d83ff5fd679471a130732786 225 Gene3D G3DSA:1.10.760.10 115 224 7.7E-25 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS01775 f89f7052d83ff5fd679471a130732786 225 PIRSF PIRSF000005 1 225 8.5E-60 T 28-03-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 MKLM6_RS01775 f89f7052d83ff5fd679471a130732786 225 SUPERFAMILY SSF46626 134 223 9.89E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS01775 f89f7052d83ff5fd679471a130732786 225 SUPERFAMILY SSF46626 25 101 8.06E-21 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS01775 f89f7052d83ff5fd679471a130732786 225 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 31 98 1.1E-6 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS09710 a067466c67eba53a61b0a93fc86b54ac 286 Pfam PF01841 Transglutaminase-like superfamily 148 235 1.0E-16 T 28-03-2018 IPR002931 Transglutaminase-like MKLM6_RS09710 a067466c67eba53a61b0a93fc86b54ac 286 Gene3D G3DSA:3.90.260.10 167 244 5.2E-4 T 28-03-2018 IPR002931 Transglutaminase-like MKLM6_RS09710 a067466c67eba53a61b0a93fc86b54ac 286 SMART SM00460 173 238 3.7E-15 T 28-03-2018 IPR002931 Transglutaminase-like MKLM6_RS09710 a067466c67eba53a61b0a93fc86b54ac 286 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 4 77 2.5E-19 T 28-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal MKLM6_RS09710 a067466c67eba53a61b0a93fc86b54ac 286 SUPERFAMILY SSF54001 84 263 4.58E-39 T 28-03-2018 MKLM6_RS14600 720a73032154d7a9ddadb8d3b2ef01ac 429 SMART SM00729 135 350 7.0E-51 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MKLM6_RS14600 720a73032154d7a9ddadb8d3b2ef01ac 429 Gene3D G3DSA:3.80.30.20 132 364 5.7E-48 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe MKLM6_RS14600 720a73032154d7a9ddadb8d3b2ef01ac 429 Pfam PF00919 Uncharacterized protein family UPF0004 3 97 9.1E-22 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 MKLM6_RS14600 720a73032154d7a9ddadb8d3b2ef01ac 429 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 139 159 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 MKLM6_RS14600 720a73032154d7a9ddadb8d3b2ef01ac 429 SUPERFAMILY SSF102114 133 361 1.57E-56 T 28-03-2018 MKLM6_RS14600 720a73032154d7a9ddadb8d3b2ef01ac 429 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 5 399 3.5E-119 T 28-03-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 MKLM6_RS14600 720a73032154d7a9ddadb8d3b2ef01ac 429 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 419 3.5E-111 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 MKLM6_RS14600 720a73032154d7a9ddadb8d3b2ef01ac 429 Pfam PF04055 Radical SAM superfamily 140 308 4.4E-24 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MKLM6_RS14600 720a73032154d7a9ddadb8d3b2ef01ac 429 Gene3D G3DSA:3.40.50.280 2 115 2.0E-5 T 28-03-2018 MKLM6_RS00120 959252a496749ea6f84f30e82ce2e60b 1616 Gene3D G3DSA:3.40.960.10 1356 1469 2.1E-21 T 28-03-2018 MKLM6_RS00120 959252a496749ea6f84f30e82ce2e60b 1616 SUPERFAMILY SSF52540 484 551 1.17E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS00120 959252a496749ea6f84f30e82ce2e60b 1616 SUPERFAMILY SSF52540 364 433 1.17E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS00120 959252a496749ea6f84f30e82ce2e60b 1616 SUPERFAMILY SSF52540 1033 1339 1.17E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS00120 959252a496749ea6f84f30e82ce2e60b 1616 Pfam PF13087 AAA domain 1148 1315 6.2E-16 T 28-03-2018 MKLM6_RS00120 959252a496749ea6f84f30e82ce2e60b 1616 SUPERFAMILY SSF52980 1356 1459 5.09E-9 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MKLM6_RS00120 959252a496749ea6f84f30e82ce2e60b 1616 Pfam PF13086 AAA domain 367 537 3.6E-9 T 28-03-2018 MKLM6_RS00120 959252a496749ea6f84f30e82ce2e60b 1616 Pfam PF04480 Protein of unknown function (DUF559) 1365 1451 6.9E-5 T 28-03-2018 IPR007569 Domain of unknown function DUF559 MKLM6_RS00120 959252a496749ea6f84f30e82ce2e60b 1616 Gene3D G3DSA:3.40.50.300 365 1126 2.5E-36 T 28-03-2018 MKLM6_RS00120 959252a496749ea6f84f30e82ce2e60b 1616 Gene3D G3DSA:3.40.50.300 1152 1345 2.2E-15 T 28-03-2018 MKLM6_RS17355 4407663a9463bec3e2c5e9a18ecdf422 112 PIRSF PIRSF025560 1 112 7.7E-27 T 28-03-2018 IPR008309 Uncharacterised conserved protein UCP025560 MKLM6_RS17355 4407663a9463bec3e2c5e9a18ecdf422 112 Pfam PF07027 Protein of unknown function (DUF1318) 22 112 1.7E-27 T 28-03-2018 IPR008309 Uncharacterised conserved protein UCP025560 MKLM6_RS11520 4c0f6ad75c2962a190637bdd45856fa8 420 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 5 102 7.8E-33 T 28-03-2018 IPR017508 HipA, N-terminal subdomain 1 MKLM6_RS11520 4c0f6ad75c2962a190637bdd45856fa8 420 Pfam PF07804 HipA-like C-terminal domain 147 377 1.1E-55 T 28-03-2018 IPR012893 HipA-like, C-terminal MKLM6_RS11520 4c0f6ad75c2962a190637bdd45856fa8 420 Pfam PF13657 HipA N-terminal domain 5 102 1.9E-25 T 28-03-2018 IPR017508 HipA, N-terminal subdomain 1 MKLM6_RS15235 5200614e1af102534e6090498ee51cc8 271 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS15235 5200614e1af102534e6090498ee51cc8 271 SMART SM00382 57 245 8.1E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS15235 5200614e1af102534e6090498ee51cc8 271 SUPERFAMILY SSF52540 29 254 9.58E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS15235 5200614e1af102534e6090498ee51cc8 271 Gene3D G3DSA:3.40.50.300 22 265 2.7E-61 T 28-03-2018 MKLM6_RS15235 5200614e1af102534e6090498ee51cc8 271 Pfam PF00005 ABC transporter 48 197 2.1E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS03450 6618e86bc68247f8184c065f84c4cf59 96 Pfam PF03692 Putative zinc- or iron-chelating domain 13 66 4.3E-5 T 28-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein MKLM6_RS04890 0c7338d11a62a710de87b903147cfc7d 140 SUPERFAMILY SSF52172 12 120 8.6E-7 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS04890 0c7338d11a62a710de87b903147cfc7d 140 Gene3D G3DSA:3.40.50.2300 5 135 5.9E-10 T 28-03-2018 MKLM6_RS06270 510bc8de75c5bf8332cfc70069aff7a7 268 Gene3D G3DSA:3.90.176.10 168 264 4.6E-5 T 28-03-2018 MKLM6_RS06270 510bc8de75c5bf8332cfc70069aff7a7 268 Pfam PF07357 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) 11 266 1.6E-99 T 28-03-2018 IPR009953 Dinitrogenase reductase ADP-ribosyltransferase GO:0009399|GO:0030701 MKLM6_RS14515 3926e345eb3c796b1ccffe1349d6df0e 447 Pfam PF04966 Carbohydrate-selective porin, OprB family 107 447 1.4E-34 T 28-03-2018 IPR007049 Carbohydrate-selective porin OprB GO:0005215|GO:0006810|GO:0016021 MKLM6_RS21180 0d1e2e7d30bdb50cf1fff5aad14070ba 157 SUPERFAMILY SSF46785 2 93 2.25E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS21180 0d1e2e7d30bdb50cf1fff5aad14070ba 157 Pfam PF01037 Lrp/AsnC ligand binding domain 69 143 3.7E-22 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MKLM6_RS21180 0d1e2e7d30bdb50cf1fff5aad14070ba 157 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site MKLM6_RS21180 0d1e2e7d30bdb50cf1fff5aad14070ba 157 SUPERFAMILY SSF54909 63 150 1.61E-19 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel MKLM6_RS21180 0d1e2e7d30bdb50cf1fff5aad14070ba 157 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 49 3.1E-21 T 28-03-2018 MKLM6_RS21180 0d1e2e7d30bdb50cf1fff5aad14070ba 157 Gene3D G3DSA:3.30.70.920 55 154 1.4E-24 T 28-03-2018 MKLM6_RS21180 0d1e2e7d30bdb50cf1fff5aad14070ba 157 SMART SM00344 3 113 7.7E-45 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MKLM6_RS21180 0d1e2e7d30bdb50cf1fff5aad14070ba 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 3.0E-19 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MKLM6_RS21180 0d1e2e7d30bdb50cf1fff5aad14070ba 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 3.0E-19 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MKLM6_RS21180 0d1e2e7d30bdb50cf1fff5aad14070ba 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 3.0E-19 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MKLM6_RS21180 0d1e2e7d30bdb50cf1fff5aad14070ba 157 Gene3D G3DSA:1.10.10.10 1 54 1.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS20030 88bb26bfea542092e08d2b239bc75adc 139 Pfam PF02566 OsmC-like protein 34 132 1.7E-16 T 28-03-2018 IPR003718 OsmC/Ohr family MKLM6_RS20030 88bb26bfea542092e08d2b239bc75adc 139 SUPERFAMILY SSF82784 1 138 4.19E-40 T 28-03-2018 IPR003718 OsmC/Ohr family MKLM6_RS20030 88bb26bfea542092e08d2b239bc75adc 139 Gene3D G3DSA:3.30.300.20 39 138 1.2E-18 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta MKLM6_RS20030 88bb26bfea542092e08d2b239bc75adc 139 Gene3D G3DSA:2.20.25.10 2 37 9.6E-18 T 28-03-2018 MKLM6_RS02645 e6c63acb5d29b9b735649249031e8448 209 Gene3D G3DSA:3.10.450.50 65 157 3.4E-25 T 28-03-2018 MKLM6_RS02645 e6c63acb5d29b9b735649249031e8448 209 Gene3D G3DSA:1.10.10.640 158 208 5.0E-5 T 28-03-2018 MKLM6_RS02645 e6c63acb5d29b9b735649249031e8448 209 PIRSF PIRSF004649 1 209 8.2E-47 T 28-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC MKLM6_RS02645 e6c63acb5d29b9b735649249031e8448 209 Pfam PF05494 MlaC protein 35 197 1.5E-47 T 28-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC MKLM6_RS15500 32e90c4aeb8ea6413a6626ae32d0b824 209 SUPERFAMILY SSF46785 11 186 4.94E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS15500 32e90c4aeb8ea6413a6626ae32d0b824 209 Gene3D G3DSA:3.30.1380.20 77 209 1.1E-5 T 28-03-2018 MKLM6_RS15500 32e90c4aeb8ea6413a6626ae32d0b824 209 Gene3D G3DSA:1.10.10.10 1 76 4.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS15500 32e90c4aeb8ea6413a6626ae32d0b824 209 Pfam PF08279 HTH domain 8 62 4.0E-6 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 MKLM6_RS19365 d3739df31c70ad11986c5aa92008906d 267 Gene3D G3DSA:1.10.287.1080 143 267 5.7E-28 T 28-03-2018 MKLM6_RS19365 d3739df31c70ad11986c5aa92008906d 267 Gene3D G3DSA:1.10.287.1080 1 127 1.4E-37 T 28-03-2018 MKLM6_RS19365 d3739df31c70ad11986c5aa92008906d 267 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 175 230 2.2E-9 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core MKLM6_RS19365 d3739df31c70ad11986c5aa92008906d 267 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 29 102 1.7E-27 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core MKLM6_RS19365 d3739df31c70ad11986c5aa92008906d 267 TIGRFAM TIGR00444 mazG: MazG family protein 12 261 7.0E-94 T 28-03-2018 IPR011551 NTP pyrophosphohydrolase MazG MKLM6_RS19365 d3739df31c70ad11986c5aa92008906d 267 SUPERFAMILY SSF101386 142 240 8.43E-26 T 28-03-2018 MKLM6_RS19365 d3739df31c70ad11986c5aa92008906d 267 SUPERFAMILY SSF101386 6 106 9.49E-24 T 28-03-2018 MKLM6_RS06105 5290ea3da4771f4b3428b3e1410ad41e 421 Pfam PF03797 Autotransporter beta-domain 146 400 1.7E-52 T 28-03-2018 IPR005546 Autotransporter beta-domain MKLM6_RS06105 5290ea3da4771f4b3428b3e1410ad41e 421 SMART SM00869 143 410 1.4E-33 T 28-03-2018 IPR005546 Autotransporter beta-domain MKLM6_RS06105 5290ea3da4771f4b3428b3e1410ad41e 421 Gene3D G3DSA:2.40.128.130 45 421 5.8E-46 T 28-03-2018 MKLM6_RS06105 5290ea3da4771f4b3428b3e1410ad41e 421 SUPERFAMILY SSF103515 129 421 2.48E-46 T 28-03-2018 IPR005546 Autotransporter beta-domain MKLM6_RS06980 7ff10db11d1c77a76c870424c3f35b6a 105 SUPERFAMILY SSF54913 3 101 2.3E-39 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MKLM6_RS06980 7ff10db11d1c77a76c870424c3f35b6a 105 Gene3D G3DSA:3.30.70.120 1 102 1.3E-41 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MKLM6_RS06980 7ff10db11d1c77a76c870424c3f35b6a 105 Pfam PF03091 CutA1 divalent ion tolerance protein 4 100 7.9E-40 T 28-03-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 MKLM6_RS17015 bc683e42a3de210d92b1feb8f5407ae7 116 Gene3D G3DSA:3.10.20.30 1 116 8.0E-22 T 28-03-2018 IPR012675 Beta-grasp domain MKLM6_RS17015 bc683e42a3de210d92b1feb8f5407ae7 116 SUPERFAMILY SSF54292 13 115 5.64E-13 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MKLM6_RS17015 bc683e42a3de210d92b1feb8f5407ae7 116 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 13 107 2.5E-14 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MKLM6_RS17015 bc683e42a3de210d92b1feb8f5407ae7 116 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 42 50 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MKLM6_RS19160 1771aa1d0e46e40f893afc8ed0e47fa9 257 TIGRFAM TIGR03078 CH4_NH3mon_ox_C: methane monooxygenase/ammonia monooxygenase, subunit C 31 246 4.4E-92 T 28-03-2018 IPR006980 Ammonia monooxygenase/particulate methane monooxygenase, subunit C MKLM6_RS19160 1771aa1d0e46e40f893afc8ed0e47fa9 257 Pfam PF04896 Ammonia monooxygenase/methane monooxygenase, subunit C 24 252 1.2E-95 T 28-03-2018 IPR006980 Ammonia monooxygenase/particulate methane monooxygenase, subunit C MKLM6_RS19160 1771aa1d0e46e40f893afc8ed0e47fa9 257 Gene3D G3DSA:1.20.1050.50 11 253 2.0E-85 T 28-03-2018 MKLM6_RS15310 81e8d60acbd80fcae0a6e0f6ffcf6843 675 Gene3D G3DSA:1.25.40.10 408 666 6.6E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS15310 81e8d60acbd80fcae0a6e0f6ffcf6843 675 SUPERFAMILY SSF48452 575 645 4.27E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS08705 8eb85d633c186c3311b4f2746dae8b5a 291 Gene3D G3DSA:1.20.120.80 71 291 4.5E-71 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08705 8eb85d633c186c3311b4f2746dae8b5a 291 SUPERFAMILY SSF81452 4 291 2.75E-76 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08705 8eb85d633c186c3311b4f2746dae8b5a 291 Pfam PF00510 Cytochrome c oxidase subunit III 149 290 6.5E-49 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08705 8eb85d633c186c3311b4f2746dae8b5a 291 Pfam PF00510 Cytochrome c oxidase subunit III 6 108 7.5E-10 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08705 8eb85d633c186c3311b4f2746dae8b5a 291 Gene3D G3DSA:1.10.287.70 1 70 1.3E-12 T 28-03-2018 MKLM6_RS05870 c025d63e38c48eb0c27eccdc879f0b7f 229 SUPERFAMILY SSF55729 9 228 3.39E-91 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS05870 c025d63e38c48eb0c27eccdc879f0b7f 229 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 41 220 3.9E-65 T 28-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 MKLM6_RS05870 c025d63e38c48eb0c27eccdc879f0b7f 229 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 229 97.388 T 28-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 MKLM6_RS05870 c025d63e38c48eb0c27eccdc879f0b7f 229 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 37 207 4.5E-75 T 28-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 MKLM6_RS16500 e3731077f3eefd29cc55ca3370a412e5 264 Gene3D G3DSA:3.60.21.10 4 253 1.9E-26 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS16500 e3731077f3eefd29cc55ca3370a412e5 264 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 9 225 6.9E-13 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 MKLM6_RS16500 e3731077f3eefd29cc55ca3370a412e5 264 SUPERFAMILY SSF56300 5 245 5.54E-31 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS15775 0239b6a0212fbe575eb421971b4730f6 302 Gene3D G3DSA:3.40.50.720 1 170 1.1E-22 T 28-03-2018 MKLM6_RS15775 0239b6a0212fbe575eb421971b4730f6 302 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 227 6.5E-34 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MKLM6_RS15775 0239b6a0212fbe575eb421971b4730f6 302 SUPERFAMILY SSF51735 1 291 6.24E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS15775 0239b6a0212fbe575eb421971b4730f6 302 Gene3D G3DSA:3.90.25.10 171 297 7.8E-21 T 28-03-2018 MKLM6_RS18880 a7a312ac129469a1e15eb907195ae303 483 Gene3D G3DSA:3.90.1300.10 1 481 2.6E-176 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MKLM6_RS18880 a7a312ac129469a1e15eb907195ae303 483 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 13 472 2.2E-183 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MKLM6_RS18880 a7a312ac129469a1e15eb907195ae303 483 Pfam PF01425 Amidase 22 462 2.2E-158 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MKLM6_RS18880 a7a312ac129469a1e15eb907195ae303 483 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 9 473 90.868 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MKLM6_RS18880 a7a312ac129469a1e15eb907195ae303 483 SUPERFAMILY SSF75304 2 479 2.09E-166 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MKLM6_RS05235 9452e2dbd4f1df663dc0905c52de9964 398 Pfam PF13662 Toprim domain 303 368 7.7E-6 T 28-03-2018 IPR006171 TOPRIM domain MKLM6_RS05235 9452e2dbd4f1df663dc0905c52de9964 398 Gene3D G3DSA:3.40.1360.10 281 395 3.0E-12 T 28-03-2018 MKLM6_RS03800 072597141a1d0abdd2e1cd66ad70ef71 110 Pfam PF01521 Iron-sulphur cluster biosynthesis 5 105 2.3E-21 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MKLM6_RS03800 072597141a1d0abdd2e1cd66ad70ef71 110 Gene3D G3DSA:2.60.300.12 5 110 1.5E-38 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MKLM6_RS03800 072597141a1d0abdd2e1cd66ad70ef71 110 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 5 109 3.0E-39 T 28-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 MKLM6_RS03800 072597141a1d0abdd2e1cd66ad70ef71 110 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 110 35.062 T 28-03-2018 IPR023063 FeS cluster insertion protein ErpA GO:0097428 MKLM6_RS03800 072597141a1d0abdd2e1cd66ad70ef71 110 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 91 108 - T 28-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 MKLM6_RS03800 072597141a1d0abdd2e1cd66ad70ef71 110 SUPERFAMILY SSF89360 5 99 9.68E-32 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MKLM6_RS11905 415c2e04fd522c2800ac0d71ef2c2b10 194 Gene3D G3DSA:3.40.50.150 5 191 7.1E-15 T 28-03-2018 MKLM6_RS11905 415c2e04fd522c2800ac0d71ef2c2b10 194 Pfam PF06962 Putative rRNA methylase 48 182 1.2E-37 T 28-03-2018 IPR010719 Putative rRNA methylase MKLM6_RS11905 415c2e04fd522c2800ac0d71ef2c2b10 194 SUPERFAMILY SSF53335 11 162 6.47E-20 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS20240 c8a6bef659224d1fec241ff04f7af623 96 Pfam PF05488 PAAR motif 19 87 1.7E-23 T 28-03-2018 IPR008727 PAAR motif MKLM6_RS09805 f0b189ae317e9a2a0dad3c4de2d2df44 246 Pfam PF01609 Transposase DDE domain 45 234 6.5E-34 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS14275 486423d77c03c6bd36857bc7d0cf8c95 340 Gene3D G3DSA:3.40.50.10320 17 334 2.0E-31 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 MKLM6_RS14275 486423d77c03c6bd36857bc7d0cf8c95 340 Pfam PF02585 GlcNAc-PI de-N-acetylase 37 206 2.2E-18 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 MKLM6_RS14275 486423d77c03c6bd36857bc7d0cf8c95 340 SUPERFAMILY SSF102588 34 128 2.49E-29 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 MKLM6_RS14275 486423d77c03c6bd36857bc7d0cf8c95 340 SUPERFAMILY SSF102588 164 316 2.49E-29 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 MKLM6_RS13600 050a023b259a58b9b27c33fd73d7ce5d 212 Pfam PF02734 DAK2 domain 32 204 2.1E-47 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MKLM6_RS13600 050a023b259a58b9b27c33fd73d7ce5d 212 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 11 204 1.9E-58 T 28-03-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 MKLM6_RS13600 050a023b259a58b9b27c33fd73d7ce5d 212 SUPERFAMILY SSF101473 3 206 6.67E-50 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MKLM6_RS13600 050a023b259a58b9b27c33fd73d7ce5d 212 SMART SM01120 32 205 4.4E-59 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MKLM6_RS06505 364ed61f6f1fc3109aa8c6d25681d444 429 PRINTS PR00173 Glutamate-aspartate symporter signature 333 352 1.3E-23 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS06505 364ed61f6f1fc3109aa8c6d25681d444 429 PRINTS PR00173 Glutamate-aspartate symporter signature 151 173 1.3E-23 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS06505 364ed61f6f1fc3109aa8c6d25681d444 429 PRINTS PR00173 Glutamate-aspartate symporter signature 12 32 1.3E-23 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS06505 364ed61f6f1fc3109aa8c6d25681d444 429 PRINTS PR00173 Glutamate-aspartate symporter signature 79 104 1.3E-23 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS06505 364ed61f6f1fc3109aa8c6d25681d444 429 PRINTS PR00173 Glutamate-aspartate symporter signature 298 324 1.3E-23 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS06505 364ed61f6f1fc3109aa8c6d25681d444 429 SUPERFAMILY SSF118215 14 408 5.1E-104 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS06505 364ed61f6f1fc3109aa8c6d25681d444 429 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 41 56 - T 28-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site MKLM6_RS06505 364ed61f6f1fc3109aa8c6d25681d444 429 Gene3D G3DSA:1.10.3860.10 9 414 2.5E-104 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS06505 364ed61f6f1fc3109aa8c6d25681d444 429 Pfam PF00375 Sodium:dicarboxylate symporter family 14 406 5.2E-97 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS09440 c40c0a6de9bae0e96bf8fa96c213869c 552 Pfam PF01935 Domain of unknown function DUF87 134 373 3.7E-34 T 28-03-2018 IPR002789 Helicase HerA, central domain MKLM6_RS09440 c40c0a6de9bae0e96bf8fa96c213869c 552 SUPERFAMILY SSF52540 129 526 2.96E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS09440 c40c0a6de9bae0e96bf8fa96c213869c 552 Gene3D G3DSA:3.40.50.300 88 524 1.1E-28 T 28-03-2018 MKLM6_RS00700 d590391a96c7540e50a0ecdf914c0ccb 158 Pfam PF16220 Domain of unknown function (DUF4880) 29 70 6.7E-11 T 28-03-2018 IPR032623 FecR, N-terminal MKLM6_RS00700 d590391a96c7540e50a0ecdf914c0ccb 158 Gene3D G3DSA:3.40.50.2300 1 154 1.4E-4 T 28-03-2018 MKLM6_RS16195 df3132ec250cce09e4f6185124120727 308 SMART SM00327 34 213 7.6E-12 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS16195 df3132ec250cce09e4f6185124120727 308 Pfam PF13519 von Willebrand factor type A domain 37 152 4.6E-11 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS16195 df3132ec250cce09e4f6185124120727 308 SUPERFAMILY SSF53300 36 180 1.45E-11 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS16195 df3132ec250cce09e4f6185124120727 308 Gene3D G3DSA:3.40.50.410 35 277 1.0E-13 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS11630 0724900ae11c0cc72f2fc958d36c3097 121 Gene3D G3DSA:1.10.260.40 7 60 1.4E-6 T 28-03-2018 MKLM6_RS21910 0eec46fffacef2ee2111c49094e6d894 383 SUPERFAMILY SSF53955 61 369 2.81E-85 T 28-03-2018 IPR023346 Lysozyme-like domain MKLM6_RS21910 0eec46fffacef2ee2111c49094e6d894 383 Pfam PF13406 Transglycosylase SLT domain 69 364 4.0E-92 T 28-03-2018 IPR031304 Transglycosylase SLT domain 2 MKLM6_RS21910 0eec46fffacef2ee2111c49094e6d894 383 Gene3D G3DSA:1.10.8.350 63 136 1.1E-8 T 28-03-2018 MKLM6_RS21910 0eec46fffacef2ee2111c49094e6d894 383 Gene3D G3DSA:1.10.8.350 137 243 3.3E-35 T 28-03-2018 MKLM6_RS21910 0eec46fffacef2ee2111c49094e6d894 383 TIGRFAM TIGR02282 MltB: lytic murein transglycosylase B 73 366 3.2E-99 T 28-03-2018 IPR011757 Lytic transglycosylase MltB MKLM6_RS21910 0eec46fffacef2ee2111c49094e6d894 383 Gene3D G3DSA:1.10.530.10 248 372 4.8E-28 T 28-03-2018 MKLM6_RS19340 d820779a62c97161a0f08f6448208806 268 Pfam PF16537 Type II secretion system protein B 208 266 4.9E-18 T 28-03-2018 IPR032389 Type II secretion system protein B MKLM6_RS17810 5e382f901360134b9f25424f2fbb04c4 539 SUPERFAMILY SSF55469 314 394 1.48E-13 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MKLM6_RS17810 5e382f901360134b9f25424f2fbb04c4 539 SUPERFAMILY SSF55469 426 524 1.48E-13 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MKLM6_RS17810 5e382f901360134b9f25424f2fbb04c4 539 Gene3D G3DSA:3.40.109.10 2 231 1.2E-23 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MKLM6_RS17810 5e382f901360134b9f25424f2fbb04c4 539 Gene3D G3DSA:3.40.109.10 300 528 2.6E-29 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MKLM6_RS17810 5e382f901360134b9f25424f2fbb04c4 539 SUPERFAMILY SSF55469 100 219 7.2E-6 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MKLM6_RS04770 65a2e2e7964fde8c377096ec6ff828d3 342 Gene3D G3DSA:2.160.10.10 140 309 3.0E-47 T 28-03-2018 MKLM6_RS04770 65a2e2e7964fde8c377096ec6ff828d3 342 Gene3D G3DSA:2.160.10.10 20 139 5.1E-7 T 28-03-2018 MKLM6_RS04770 65a2e2e7964fde8c377096ec6ff828d3 342 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 118 145 3.6E-4 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS04770 65a2e2e7964fde8c377096ec6ff828d3 342 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 224 258 3.9E-5 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS04770 65a2e2e7964fde8c377096ec6ff828d3 342 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 146 180 6.5E-10 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS04770 65a2e2e7964fde8c377096ec6ff828d3 342 SUPERFAMILY SSF51161 33 315 4.31E-71 T 28-03-2018 IPR011004 Trimeric LpxA-like MKLM6_RS04770 65a2e2e7964fde8c377096ec6ff828d3 342 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 23 88 1.2E-11 T 28-03-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 MKLM6_RS04770 65a2e2e7964fde8c377096ec6ff828d3 342 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 2 326 31.799 T 28-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 MKLM6_RS04770 65a2e2e7964fde8c377096ec6ff828d3 342 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 5 329 3.1E-98 T 28-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 MKLM6_RS22670 661d8edb2d7b15eb7ee108b5c51d26ff 108 Pfam PF07110 EthD domain 14 84 3.4E-6 T 28-03-2018 IPR009799 EthD domain MKLM6_RS22670 661d8edb2d7b15eb7ee108b5c51d26ff 108 SUPERFAMILY SSF54909 4 103 4.65E-15 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel MKLM6_RS22670 661d8edb2d7b15eb7ee108b5c51d26ff 108 Gene3D G3DSA:3.30.70.100 1 106 7.0E-15 T 28-03-2018 MKLM6_RS22670 661d8edb2d7b15eb7ee108b5c51d26ff 108 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 4 105 7.7E-16 T 28-03-2018 IPR009799 EthD domain MKLM6_RS03575 e781d1cf68cd055177d468ed9e31c4ff 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 85 98 8.1E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS03575 e781d1cf68cd055177d468ed9e31c4ff 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 112 8.1E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS03575 e781d1cf68cd055177d468ed9e31c4ff 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 42 57 8.1E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS03575 e781d1cf68cd055177d468ed9e31c4ff 258 Pfam PF12697 Alpha/beta hydrolase family 19 248 1.8E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS03575 e781d1cf68cd055177d468ed9e31c4ff 258 Gene3D G3DSA:3.40.50.1820 6 256 2.5E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS03575 e781d1cf68cd055177d468ed9e31c4ff 258 SUPERFAMILY SSF53474 4 254 3.13E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS02620 d007447592b5b76e709a895c0e6dabcf 447 Gene3D G3DSA:2.60.120.10 36 159 2.7E-5 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS02620 d007447592b5b76e709a895c0e6dabcf 447 Pfam PF08668 HDOD domain 189 329 5.4E-33 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD MKLM6_RS02620 d007447592b5b76e709a895c0e6dabcf 447 SUPERFAMILY SSF51206 46 146 2.36E-9 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like MKLM6_RS02620 d007447592b5b76e709a895c0e6dabcf 447 SUPERFAMILY SSF109604 174 432 1.38E-43 T 28-03-2018 MKLM6_RS02620 d007447592b5b76e709a895c0e6dabcf 447 Gene3D G3DSA:1.10.3210.10 168 418 7.0E-33 T 28-03-2018 MKLM6_RS11090 44b0d697c135c603bdaddbfb348e29b0 285 Pfam PF00892 EamA-like transporter family 137 271 6.7E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MKLM6_RS11090 44b0d697c135c603bdaddbfb348e29b0 285 SUPERFAMILY SSF103481 32 125 1.14E-8 T 28-03-2018 MKLM6_RS11090 44b0d697c135c603bdaddbfb348e29b0 285 SUPERFAMILY SSF103481 197 273 1.57E-10 T 28-03-2018 MKLM6_RS07545 9edeb4769c2fcf3b21f27dba81d403a5 221 Gene3D G3DSA:3.40.50.2300 1 121 2.5E-30 T 28-03-2018 MKLM6_RS07545 9edeb4769c2fcf3b21f27dba81d403a5 221 SMART SM00862 147 218 1.3E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS07545 9edeb4769c2fcf3b21f27dba81d403a5 221 Gene3D G3DSA:1.10.10.10 122 221 5.3E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS07545 9edeb4769c2fcf3b21f27dba81d403a5 221 Pfam PF00072 Response regulator receiver domain 4 114 5.0E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS07545 9edeb4769c2fcf3b21f27dba81d403a5 221 SUPERFAMILY SSF52172 1 171 5.73E-34 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS07545 9edeb4769c2fcf3b21f27dba81d403a5 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 217 1.3E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MKLM6_RS07545 9edeb4769c2fcf3b21f27dba81d403a5 221 SMART SM00448 1 114 3.9E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS16715 e7f57129623c999dd037e946cea085b1 135 Gene3D G3DSA:1.10.490.10 6 121 6.9E-23 T 28-03-2018 MKLM6_RS16715 e7f57129623c999dd037e946cea085b1 135 SUPERFAMILY SSF46458 9 119 1.71E-24 T 28-03-2018 IPR009050 Globin-like MKLM6_RS16715 e7f57129623c999dd037e946cea085b1 135 Pfam PF01152 Bacterial-like globin 10 110 3.5E-6 T 28-03-2018 IPR001486 Truncated hemoglobin GO:0019825 MKLM6_RS18790 cb2fd77e8f23e84fab8e1610b80cc75c 226 Pfam PF13861 FlgD Tudor-like domain 86 223 1.3E-13 T 28-03-2018 IPR025963 FlgD Tudor-like domain MKLM6_RS18790 cb2fd77e8f23e84fab8e1610b80cc75c 226 Pfam PF13860 FlgD Ig-like domain 110 179 3.3E-19 T 28-03-2018 IPR025965 FlgD Ig-like domain MKLM6_RS18790 cb2fd77e8f23e84fab8e1610b80cc75c 226 Pfam PF03963 Flagellar hook capping protein - N-terminal region 15 77 1.5E-22 T 28-03-2018 IPR005648 Flagellar hook capping protein MKLM6_RS06585 40a33bdc1a370bdc1e4396575347cde4 290 PIRSF PIRSF015558 3 289 1.6E-71 T 28-03-2018 IPR016634 WYL domain protein, s026 type MKLM6_RS06585 40a33bdc1a370bdc1e4396575347cde4 290 Pfam PF13280 WYL domain 128 214 2.7E-9 T 28-03-2018 IPR026881 WYL domain MKLM6_RS12445 0a6bb2181f78b554c8fc23dbf58e2aac 184 Pfam PF03748 Flagellar basal body-associated protein FliL 85 184 4.3E-20 T 28-03-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 MKLM6_RS17095 4341b3b280e110f087db3d655a9a717f 453 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 45 65 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS17095 4341b3b280e110f087db3d655a9a717f 453 Pfam PF07963 Prokaryotic N-terminal methylation motif 44 66 6.8E-5 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS17095 4341b3b280e110f087db3d655a9a717f 453 Gene3D G3DSA:3.30.700.10 47 371 0.0019 T 28-03-2018 MKLM6_RS17095 4341b3b280e110f087db3d655a9a717f 453 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 44 67 7.4E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS17875 101b841f315adf22bb13cc2a2b46acd8 520 Pfam PF05954 Phage late control gene D protein (GPD) 60 320 3.9E-20 T 28-03-2018 MKLM6_RS17875 101b841f315adf22bb13cc2a2b46acd8 520 Gene3D G3DSA:3.55.50.10 102 194 2.4E-5 T 28-03-2018 MKLM6_RS17875 101b841f315adf22bb13cc2a2b46acd8 520 SUPERFAMILY SSF69255 343 418 7.59E-8 T 28-03-2018 MKLM6_RS17875 101b841f315adf22bb13cc2a2b46acd8 520 SUPERFAMILY SSF69279 257 333 3.83E-7 T 28-03-2018 MKLM6_RS17875 101b841f315adf22bb13cc2a2b46acd8 520 SUPERFAMILY SSF69279 8 176 1.11E-16 T 28-03-2018 MKLM6_RS17875 101b841f315adf22bb13cc2a2b46acd8 520 Gene3D G3DSA:2.40.50.260 338 433 5.1E-13 T 28-03-2018 MKLM6_RS06775 b7f940f16f0473976bbf30637d05e0cf 374 Gene3D G3DSA:1.10.3470.10 42 358 2.6E-29 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like MKLM6_RS06775 b7f940f16f0473976bbf30637d05e0cf 374 Pfam PF02653 Branched-chain amino acid transport system / permease component 48 342 5.4E-37 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 MKLM6_RS06775 b7f940f16f0473976bbf30637d05e0cf 374 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 39 353 2.5E-132 T 28-03-2018 IPR017778 ABC transporter, urea, permease protein, UrtC MKLM6_RS09840 6a0c824a6b6e7636834a7d67439c4a1f 458 Pfam PF06123 Inner membrane protein CreD 6 441 4.9E-135 T 28-03-2018 IPR010364 Uncharacterised protein family, inner membrane CreD MKLM6_RS09840 6a0c824a6b6e7636834a7d67439c4a1f 458 PIRSF PIRSF004548 1 452 6.5E-132 T 28-03-2018 IPR010364 Uncharacterised protein family, inner membrane CreD MKLM6_RS03845 1ae3a79f1ef9151df2cbfb12dc9cdb9b 162 Pfam PF00578 AhpC/TSA family 29 143 1.5E-22 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MKLM6_RS03845 1ae3a79f1ef9151df2cbfb12dc9cdb9b 162 Gene3D G3DSA:3.40.30.10 20 162 9.8E-30 T 28-03-2018 MKLM6_RS03845 1ae3a79f1ef9151df2cbfb12dc9cdb9b 162 SUPERFAMILY SSF52833 25 162 2.3E-34 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS17890 227f14a25545e55b0b6aa84ed118a64c 868 Pfam PF04865 Baseplate J-like protein 273 442 1.7E-10 T 28-03-2018 IPR006949 Baseplate protein J-like MKLM6_RS17890 227f14a25545e55b0b6aa84ed118a64c 868 TIGRFAM TIGR02243 TIGR02243: putative baseplate assembly protein 192 492 8.9E-47 T 28-03-2018 IPR011749 Conserved hypothetical protein CHP02243 MKLM6_RS17890 227f14a25545e55b0b6aa84ed118a64c 868 Gene3D G3DSA:2.130.10.10 479 830 2.4E-10 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MKLM6_RS17890 227f14a25545e55b0b6aa84ed118a64c 868 SUPERFAMILY SSF50939 644 737 2.16E-8 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 MKLM6_RS17890 227f14a25545e55b0b6aa84ed118a64c 868 SUPERFAMILY SSF50939 480 597 2.16E-8 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 MKLM6_RS17985 098ee1c188436b6c7d5f2de3992246d9 213 Gene3D G3DSA:1.10.730.10 17 143 4.6E-4 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MKLM6_RS17985 098ee1c188436b6c7d5f2de3992246d9 213 Pfam PF01865 Protein of unknown function DUF47 26 210 1.3E-12 T 28-03-2018 IPR018445 Putative phosphate transport regulator MKLM6_RS05795 56e8096f8ff443b18ce78442fce51bd2 242 Pfam PF01863 Protein of unknown function DUF45 18 234 2.8E-57 T 28-03-2018 IPR002725 Protein of unknown function DUF45 MKLM6_RS05455 3a678c14311c57a7b30b6d6dd77788ec 760 Gene3D G3DSA:3.20.20.140 29 77 0.0045 T 28-03-2018 MKLM6_RS10310 3b6b7cb97c3785f49989382c7d0373f4 110 SUPERFAMILY SSF52091 7 98 1.96E-16 T 28-03-2018 IPR002645 STAS domain MKLM6_RS10310 3b6b7cb97c3785f49989382c7d0373f4 110 Gene3D G3DSA:3.30.750.24 1 106 2.1E-16 T 28-03-2018 IPR002645 STAS domain MKLM6_RS10310 3b6b7cb97c3785f49989382c7d0373f4 110 Pfam PF13466 STAS domain 15 94 3.4E-16 T 28-03-2018 IPR002645 STAS domain MKLM6_RS12520 b5b547776295e57409cc471c1c867e10 338 Gene3D G3DSA:3.40.630.10 4 293 1.2E-37 T 28-03-2018 MKLM6_RS12520 b5b547776295e57409cc471c1c867e10 338 ProSitePatterns PS00132 Zinc carboxypeptidases, zinc-binding region 1 signature. 53 75 - T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 MKLM6_RS12520 b5b547776295e57409cc471c1c867e10 338 SUPERFAMILY SSF53187 37 311 6.62E-47 T 28-03-2018 MKLM6_RS12520 b5b547776295e57409cc471c1c867e10 338 Pfam PF00246 Zinc carboxypeptidase 39 225 3.2E-19 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 MKLM6_RS04310 d6438d908f4f72aaab0abd508d68d8eb 371 Gene3D G3DSA:1.10.150.130 7 108 9.9E-9 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal MKLM6_RS04310 d6438d908f4f72aaab0abd508d68d8eb 371 SUPERFAMILY SSF56349 15 330 1.65E-22 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS04310 d6438d908f4f72aaab0abd508d68d8eb 371 Pfam PF00589 Phage integrase family 136 319 1.2E-9 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS04310 d6438d908f4f72aaab0abd508d68d8eb 371 Gene3D G3DSA:1.10.443.10 131 336 1.2E-20 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS16575 28e1562b5e5c6816041411c1cc353ea7 79 Pfam PF06146 Phosphate-starvation-inducible E 9 69 6.6E-11 T 28-03-2018 IPR020948 Phosphate-starvation-induced PsiE-like MKLM6_RS16575 28e1562b5e5c6816041411c1cc353ea7 79 TIGRFAM TIGR02647 DNA: TIGR02647 family protein 1 76 1.3E-32 T 28-03-2018 IPR013468 Conserved hypothetical protein CHP02647 MKLM6_RS07000 a33e7e8de8169410dd8ed1ead104eccd 147 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 147 4.8E-57 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MKLM6_RS07000 a33e7e8de8169410dd8ed1ead104eccd 147 SUPERFAMILY SSF51230 72 147 2.09E-24 T 28-03-2018 IPR011053 Single hybrid motif MKLM6_RS07000 a33e7e8de8169410dd8ed1ead104eccd 147 Pfam PF00364 Biotin-requiring enzyme 73 146 5.9E-24 T 28-03-2018 IPR000089 Biotin/lipoyl attachment MKLM6_RS07000 a33e7e8de8169410dd8ed1ead104eccd 147 Gene3D G3DSA:2.40.50.100 4 147 2.4E-19 T 28-03-2018 MKLM6_RS07000 a33e7e8de8169410dd8ed1ead104eccd 147 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 108 121 4.3E-18 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MKLM6_RS07000 a33e7e8de8169410dd8ed1ead104eccd 147 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 76 89 4.3E-18 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MKLM6_RS07000 a33e7e8de8169410dd8ed1ead104eccd 147 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 93 107 4.3E-18 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MKLM6_RS07015 82e705d635cf5588ea44e1d0c316be69 212 TIGRFAM TIGR02098 MJ0042_CXXC: MJ0042 family finger-like domain 1 37 2.5E-5 T 28-03-2018 IPR011723 Zinc finger/thioredoxin putative MKLM6_RS07015 82e705d635cf5588ea44e1d0c316be69 212 Pfam PF11906 Protein of unknown function (DUF3426) 74 210 6.2E-25 T 28-03-2018 IPR021834 Protein of unknown function DUF3426 MKLM6_RS02145 a841a307c1b2c9d5fc572abf2d790e4d 328 SUPERFAMILY SSF53300 87 268 1.13E-36 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS02145 a841a307c1b2c9d5fc572abf2d790e4d 328 Pfam PF00092 von Willebrand factor type A domain 90 284 3.5E-29 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS02145 a841a307c1b2c9d5fc572abf2d790e4d 328 Gene3D G3DSA:3.40.50.410 82 310 3.4E-44 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS02145 a841a307c1b2c9d5fc572abf2d790e4d 328 SMART SM00327 88 291 2.8E-21 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS03760 45f28f1ef64de01dd3573889d3ae361f 99 SUPERFAMILY SSF46626 17 96 1.45E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS03760 45f28f1ef64de01dd3573889d3ae361f 99 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 26 93 8.2E-12 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS03760 45f28f1ef64de01dd3573889d3ae361f 99 Gene3D G3DSA:1.10.760.10 14 94 1.1E-10 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS15545 6e297fc96fca7d1285acf8931c6ba946 148 Pfam PF06853 Protein of unknown function (DUF1249) 23 138 1.2E-31 T 28-03-2018 IPR009659 Protein of unknown function DUF1249 MKLM6_RS10300 42aa6ccb2635757359855301d26d6612 403 SUPERFAMILY SSF58104 147 351 1.83E-36 T 28-03-2018 MKLM6_RS10300 42aa6ccb2635757359855301d26d6612 403 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 175 326 7.0E-27 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS10300 42aa6ccb2635757359855301d26d6612 403 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 198 225 1.4E-14 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MKLM6_RS10300 42aa6ccb2635757359855301d26d6612 403 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 227 256 1.4E-14 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MKLM6_RS10300 42aa6ccb2635757359855301d26d6612 403 Gene3D G3DSA:1.10.287.950 105 401 8.2E-33 T 28-03-2018 MKLM6_RS10300 42aa6ccb2635757359855301d26d6612 403 SMART SM00283 104 351 6.1E-6 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MKLM6_RS20140 002389047c2791ceeb1cbab35dfd9a19 733 Gene3D G3DSA:3.40.50.300 398 627 9.1E-22 T 28-03-2018 MKLM6_RS20140 002389047c2791ceeb1cbab35dfd9a19 733 Hamap MF_00983 Probable primosomal protein N' [priA]. 14 732 24.808 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 MKLM6_RS20140 002389047c2791ceeb1cbab35dfd9a19 733 Pfam PF04851 Type III restriction enzyme, res subunit 203 362 7.0E-13 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MKLM6_RS20140 002389047c2791ceeb1cbab35dfd9a19 733 SUPERFAMILY SSF52540 505 602 3.27E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS20140 002389047c2791ceeb1cbab35dfd9a19 733 SUPERFAMILY SSF52540 215 442 3.27E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS20140 002389047c2791ceeb1cbab35dfd9a19 733 TIGRFAM TIGR00595 priA: primosomal protein N' 223 730 4.5E-182 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 MKLM6_RS20140 002389047c2791ceeb1cbab35dfd9a19 733 Pfam PF00271 Helicase conserved C-terminal domain 501 590 3.8E-6 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS20140 002389047c2791ceeb1cbab35dfd9a19 733 SMART SM00487 197 394 2.7E-15 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MKLM6_RS20140 002389047c2791ceeb1cbab35dfd9a19 733 SMART SM00490 494 591 2.3E-7 T 28-03-2018 IPR001650 Helicase, C-terminal MKLM6_RS20140 002389047c2791ceeb1cbab35dfd9a19 733 Gene3D G3DSA:3.40.50.300 198 364 4.8E-24 T 28-03-2018 MKLM6_RS13380 01443bc82b04abb10a309d44dd3df781 167 Pfam PF13689 Domain of unknown function (DUF4154) 22 161 1.7E-42 T 28-03-2018 IPR025293 Protein of unknown function DUF4154 MKLM6_RS21545 f3a33b7d50cbec36df021e3c7a8bab92 317 SUPERFAMILY SSF54427 187 315 3.46E-13 T 28-03-2018 IPR032710 NTF2-like domain MKLM6_RS21545 f3a33b7d50cbec36df021e3c7a8bab92 317 SMART SM00978 184 314 2.7E-29 T 28-03-2018 IPR007379 Tim44-like domain MKLM6_RS21545 f3a33b7d50cbec36df021e3c7a8bab92 317 Pfam PF04280 Tim44-like domain 189 314 4.4E-14 T 28-03-2018 IPR007379 Tim44-like domain MKLM6_RS09755 0dec55ef53796ae91a18d0dfe86dc357 80 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 29 65 1.6E-7 T 28-03-2018 IPR010260 DNA-binding transcriptional activator AlpA MKLM6_RS19505 132865b6b309fc41696bbf87053cf382 181 SUPERFAMILY SSF53098 4 180 2.94E-47 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS19505 132865b6b309fc41696bbf87053cf382 181 SMART SM00479 7 180 1.1E-21 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MKLM6_RS19505 132865b6b309fc41696bbf87053cf382 181 Hamap MF_00045 Oligoribonuclease [orn]. 3 181 43.897 T 28-03-2018 IPR022894 Oligoribonuclease GO:0000175 MKLM6_RS19505 132865b6b309fc41696bbf87053cf382 181 Pfam PF00929 Exonuclease 9 170 2.7E-33 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MKLM6_RS19505 132865b6b309fc41696bbf87053cf382 181 Gene3D G3DSA:3.30.420.10 2 181 1.6E-26 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS02320 4c17b89ec4ad1877e3cbe10dc67d7196 210 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 42 49 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MKLM6_RS02320 4c17b89ec4ad1877e3cbe10dc67d7196 210 Gene3D G3DSA:3.40.1050.10 2 203 4.2E-67 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MKLM6_RS02320 4c17b89ec4ad1877e3cbe10dc67d7196 210 SUPERFAMILY SSF53056 3 193 2.35E-66 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MKLM6_RS02320 4c17b89ec4ad1877e3cbe10dc67d7196 210 Pfam PF00484 Carbonic anhydrase 38 189 3.1E-50 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MKLM6_RS02320 4c17b89ec4ad1877e3cbe10dc67d7196 210 SMART SM00947 30 194 3.3E-61 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MKLM6_RS02320 4c17b89ec4ad1877e3cbe10dc67d7196 210 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 82 102 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MKLM6_RS15095 6a4090194091ab37af5ad1e89ffc3f88 293 Gene3D G3DSA:2.40.128.130 22 293 1.6E-7 T 28-03-2018 MKLM6_RS13415 953349f9355218bf7c2191805082388b 171 Gene3D G3DSA:3.10.129.10 1 171 9.8E-50 T 28-03-2018 MKLM6_RS13415 953349f9355218bf7c2191805082388b 171 Hamap MF_00405 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase [fabA]. 1 171 51.754 T 28-03-2018 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MKLM6_RS13415 953349f9355218bf7c2191805082388b 171 SUPERFAMILY SSF54637 2 168 2.09E-57 T 28-03-2018 IPR029069 HotDog domain MKLM6_RS13415 953349f9355218bf7c2191805082388b 171 Pfam PF07977 FabA-like domain 28 157 1.9E-53 T 28-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MKLM6_RS13415 953349f9355218bf7c2191805082388b 171 TIGRFAM TIGR01749 fabA: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA 3 170 1.5E-96 T 28-03-2018 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MKLM6_RS15205 70166aaf268270c2d4b7e9640c424d80 292 SUPERFAMILY SSF69572 6 270 1.57E-51 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MKLM6_RS15205 70166aaf268270c2d4b7e9640c424d80 292 Pfam PF00899 ThiF family 12 260 2.8E-41 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MKLM6_RS15205 70166aaf268270c2d4b7e9640c424d80 292 Gene3D G3DSA:3.40.50.720 2 270 1.2E-39 T 28-03-2018 MKLM6_RS22450 8405dbe3e5463a31de61ae5f2414316f 94 ProSitePatterns PS00018 EF-hand calcium-binding domain. 28 40 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site MKLM6_RS22450 8405dbe3e5463a31de61ae5f2414316f 94 SUPERFAMILY SSF47473 12 86 4.76E-5 T 28-03-2018 IPR011992 EF-hand domain pair MKLM6_RS22450 8405dbe3e5463a31de61ae5f2414316f 94 ProSitePatterns PS00018 EF-hand calcium-binding domain. 65 77 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site MKLM6_RS22450 8405dbe3e5463a31de61ae5f2414316f 94 Gene3D G3DSA:1.10.238.10 4 93 9.4E-5 T 28-03-2018 MKLM6_RS00160 35297adaf5e0c7ce4897f77b4f04b692 322 TIGRFAM TIGR03299 LGT_TIGR03299: phage/plasmid-like protein TIGR03299 6 318 1.2E-117 T 28-03-2018 IPR017686 Phage/plasmid-like protein MKLM6_RS00160 35297adaf5e0c7ce4897f77b4f04b692 322 Pfam PF06067 Domain of unknown function (DUF932) 77 302 7.5E-79 T 28-03-2018 IPR026325 Protein of unknown function DUF932 MKLM6_RS10935 2cd853c9b601e275606b5b535e035ae2 461 Pfam PF12040 Domain of unknown function (DUF3526) 281 424 2.1E-16 T 28-03-2018 IPR021913 Protein of unknown function DUF3526 MKLM6_RS14855 9933e9bffe0dc6aec0d8b8a73f9d3cb3 261 SUPERFAMILY SSF56784 79 229 5.51E-10 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS14855 9933e9bffe0dc6aec0d8b8a73f9d3cb3 261 SUPERFAMILY SSF56784 8 50 5.51E-10 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS14855 9933e9bffe0dc6aec0d8b8a73f9d3cb3 261 Gene3D G3DSA:3.40.50.1000 6 237 3.5E-7 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS08290 5f7cebcd7165f2a048fe82c2287f2572 94 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 2 47 1.6E-19 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 MKLM6_RS08290 5f7cebcd7165f2a048fe82c2287f2572 94 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 69 19.142 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 MKLM6_RS08290 5f7cebcd7165f2a048fe82c2287f2572 94 Pfam PF02416 mttA/Hcf106 family 4 48 5.8E-14 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 MKLM6_RS05740 8c2767fc07c3e2c061e69d5bf4066373 238 Pfam PF08856 Protein of unknown function (DUF1826) 36 236 7.9E-65 T 28-03-2018 IPR014955 Protein of unknown function DUF1826 MKLM6_RS05930 b240ae95508c361a1f753a7fefe9d9ff 249 Pfam PF10571 Uncharacterised protein family UPF0547 2 25 1.2E-6 T 28-03-2018 IPR018886 Uncharacterised domain UPF0547 MKLM6_RS01700 80a14a0140a38cba3599b89aa3a66087 635 Pfam PF04134 Protein of unknown function, DUF393 294 403 7.7E-16 T 28-03-2018 IPR007263 Protein of unknown function DUF393 MKLM6_RS01700 80a14a0140a38cba3599b89aa3a66087 635 SMART SM00752 14 277 8.9E-31 T 28-03-2018 IPR011020 HTTM Reactome: R-HSA-159740 MKLM6_RS06490 4dcc1574aa73262ae0e2a01e2e841ba9 405 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 84 313 2.5E-18 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MKLM6_RS06490 4dcc1574aa73262ae0e2a01e2e841ba9 405 Gene3D G3DSA:2.40.50.100 184 394 1.6E-7 T 28-03-2018 MKLM6_RS06490 4dcc1574aa73262ae0e2a01e2e841ba9 405 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 60 394 6.3E-85 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MKLM6_RS06490 4dcc1574aa73262ae0e2a01e2e841ba9 405 Gene3D G3DSA:2.40.50.100 84 156 1.2E-17 T 28-03-2018 MKLM6_RS06490 4dcc1574aa73262ae0e2a01e2e841ba9 405 SUPERFAMILY SSF111369 74 318 2.62E-67 T 28-03-2018 MKLM6_RS11900 6177fd4d92e8a01a5c264993355d8689 104 Pfam PF06865 Protein of unknown function (DUF1255) 11 102 2.1E-38 T 28-03-2018 IPR009664 Pyrimidine/purine nucleoside phosphorylase MKLM6_RS11900 6177fd4d92e8a01a5c264993355d8689 104 Gene3D G3DSA:2.60.120.10 2 102 5.7E-42 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS11900 6177fd4d92e8a01a5c264993355d8689 104 SUPERFAMILY SSF51182 10 103 2.05E-34 T 28-03-2018 IPR011051 RmlC-like cupin domain MKLM6_RS11900 6177fd4d92e8a01a5c264993355d8689 104 Hamap MF_01537 UPF0345 protein YaiE [yaiE]. 10 103 29.206 T 28-03-2018 IPR009664 Pyrimidine/purine nucleoside phosphorylase MKLM6_RS21515 536cd1f3a339ee21b94c638a7e81bfb1 235 Pfam PF11582 Protein of unknown function (DUF3240) 165 235 3.3E-6 T 28-03-2018 IPR021634 Protein of unknown function DUF3240 MKLM6_RS21515 536cd1f3a339ee21b94c638a7e81bfb1 235 SUPERFAMILY SSF54928 3 101 5.27E-6 T 28-03-2018 IPR000504 RNA recognition motif domain GO:0003676 MKLM6_RS21515 536cd1f3a339ee21b94c638a7e81bfb1 235 Gene3D G3DSA:3.30.70.330 1 137 1.5E-5 T 28-03-2018 MKLM6_RS20920 5199164c4f88fcda22be6638340ded76 318 SUPERFAMILY SSF52540 129 259 1.23E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS20920 5199164c4f88fcda22be6638340ded76 318 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 152 247 3.0E-18 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MKLM6_RS20920 5199164c4f88fcda22be6638340ded76 318 Gene3D G3DSA:3.40.50.300 90 284 1.4E-14 T 28-03-2018 MKLM6_RS21375 67b3d0e9eb76d8edab354b975e4e3013 281 Pfam PF13525 Outer membrane lipoprotein 45 248 6.9E-67 T 28-03-2018 MKLM6_RS21375 67b3d0e9eb76d8edab354b975e4e3013 281 Gene3D G3DSA:1.25.20.10 44 277 6.5E-19 T 28-03-2018 MKLM6_RS21375 67b3d0e9eb76d8edab354b975e4e3013 281 SUPERFAMILY SSF48452 49 132 9.11E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS21375 67b3d0e9eb76d8edab354b975e4e3013 281 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 4 255 36.642 T 28-03-2018 IPR017689 Outer membrane protein assembly factor BamD MKLM6_RS21375 67b3d0e9eb76d8edab354b975e4e3013 281 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 7 257 4.6E-83 T 28-03-2018 IPR017689 Outer membrane protein assembly factor BamD MKLM6_RS00085 620bd7468c6720da415de0312fecd079 502 Pfam PF13148 Protein of unknown function (DUF3987) 32 405 8.1E-84 T 28-03-2018 IPR025048 Protein of unknown function DUF3987) MKLM6_RS14930 bfb60e4b1364ffb7338309d4c8f558b4 1040 Gene3D G3DSA:3.40.50.300 54 263 2.6E-9 T 28-03-2018 MKLM6_RS14930 bfb60e4b1364ffb7338309d4c8f558b4 1040 SUPERFAMILY SSF52540 92 233 3.2E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS17940 965f4546f2627a3f6aa498880e970809 431 Pfam PF02321 Outer membrane efflux protein 233 425 1.6E-32 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS17940 965f4546f2627a3f6aa498880e970809 431 Pfam PF02321 Outer membrane efflux protein 20 206 1.5E-21 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS17940 965f4546f2627a3f6aa498880e970809 431 PIRSF PIRSF001892 2 431 3.0E-101 T 28-03-2018 IPR028351 Cyclolysin transport protein CyaE GO:0005215 MKLM6_RS17940 965f4546f2627a3f6aa498880e970809 431 SUPERFAMILY SSF56954 14 426 5.89E-77 T 28-03-2018 MKLM6_RS17940 965f4546f2627a3f6aa498880e970809 431 Gene3D G3DSA:1.20.1600.10 4 428 2.2E-73 T 28-03-2018 MKLM6_RS13030 042fa283e24c875fb460d0b42ae2f793 122 SUPERFAMILY SSF56349 2 100 1.12E-18 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MKLM6_RS13030 042fa283e24c875fb460d0b42ae2f793 122 Gene3D G3DSA:1.10.443.10 1 104 5.5E-11 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS13030 042fa283e24c875fb460d0b42ae2f793 122 Pfam PF00589 Phage integrase family 14 90 1.1E-9 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MKLM6_RS04055 d634cfcfcd888d3807e45599bfceb242 499 Pfam PF16760 Starch/carbohydrate-binding module (family 53) 148 232 8.3E-9 T 28-03-2018 IPR005085 Carbohydrate binding module family 25 GO:2001070 MKLM6_RS04055 d634cfcfcd888d3807e45599bfceb242 499 Gene3D G3DSA:3.60.10.10 238 497 6.4E-29 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MKLM6_RS04055 d634cfcfcd888d3807e45599bfceb242 499 SUPERFAMILY SSF56219 236 496 1.57E-32 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MKLM6_RS04055 d634cfcfcd888d3807e45599bfceb242 499 Gene3D G3DSA:2.60.40.10 15 120 3.2E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS04055 d634cfcfcd888d3807e45599bfceb242 499 Gene3D G3DSA:2.60.40.10 135 237 1.1E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS04055 d634cfcfcd888d3807e45599bfceb242 499 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 258 489 4.4E-11 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MKLM6_RS13800 bc18905b100013925376b1e054dd8bc3 396 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 19 377 32.691 T 28-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 MKLM6_RS13800 bc18905b100013925376b1e054dd8bc3 396 PIRSF PIRSF001549 6 391 5.3E-42 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 MKLM6_RS13800 bc18905b100013925376b1e054dd8bc3 396 Gene3D G3DSA:3.30.930.10 19 317 6.6E-42 T 28-03-2018 MKLM6_RS13800 bc18905b100013925376b1e054dd8bc3 396 Pfam PF13393 Histidyl-tRNA synthetase 12 325 8.3E-117 T 28-03-2018 MKLM6_RS13800 bc18905b100013925376b1e054dd8bc3 396 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 15 328 9.2E-89 T 28-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 MKLM6_RS13800 bc18905b100013925376b1e054dd8bc3 396 SUPERFAMILY SSF55681 7 336 2.71E-55 T 28-03-2018 MKLM6_RS11880 e406330f6576741f26ff5ad0836aeec5 415 Pfam PF02687 FtsX-like permease family 302 408 3.0E-10 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MKLM6_RS11880 e406330f6576741f26ff5ad0836aeec5 415 Gene3D G3DSA:1.20.1250.20 1 405 0.004 T 28-03-2018 MKLM6_RS11880 e406330f6576741f26ff5ad0836aeec5 415 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 5 415 1.5E-154 T 28-03-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 MKLM6_RS11880 e406330f6576741f26ff5ad0836aeec5 415 Pfam PF12704 MacB-like periplasmic core domain 27 212 4.9E-17 T 28-03-2018 IPR025857 MacB-like periplasmic core domain MKLM6_RS01235 25e7362f028fa5f9c3844b38459c156c 707 Gene3D G3DSA:2.40.170.20 176 707 2.0E-27 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS01235 25e7362f028fa5f9c3844b38459c156c 707 Pfam PF07715 TonB-dependent Receptor Plug Domain 59 167 4.0E-14 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS01235 25e7362f028fa5f9c3844b38459c156c 707 Gene3D G3DSA:2.170.130.10 30 175 3.5E-15 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS01235 25e7362f028fa5f9c3844b38459c156c 707 SUPERFAMILY SSF56935 33 707 1.32E-63 T 28-03-2018 MKLM6_RS13830 daaef9456661848f24573fdb2338711a 229 Gene3D G3DSA:3.20.20.140 8 227 7.0E-40 T 28-03-2018 MKLM6_RS13830 daaef9456661848f24573fdb2338711a 229 SUPERFAMILY SSF51556 7 226 1.75E-42 T 28-03-2018 IPR032466 Metal-dependent hydrolase MKLM6_RS13830 daaef9456661848f24573fdb2338711a 229 PIRSF PIRSF005902 2 229 4.5E-35 T 28-03-2018 IPR001130 TatD family GO:0016788 MKLM6_RS13830 daaef9456661848f24573fdb2338711a 229 Pfam PF01026 TatD related DNase 40 226 4.6E-34 T 28-03-2018 IPR001130 TatD family GO:0016788 MKLM6_RS12670 0c2df3c7342349fe9fa2cec79be3dcf4 264 Pfam PF09990 Predicted membrane protein (DUF2231) 87 189 3.9E-15 T 28-03-2018 IPR019251 Domain of unknown function DUF2231, transmembrane MKLM6_RS01580 ea355393251e9d55504f7aa3f2ab7ec2 154 SUPERFAMILY SSF54928 2 99 5.89E-6 T 28-03-2018 IPR000504 RNA recognition motif domain GO:0003676 MKLM6_RS01580 ea355393251e9d55504f7aa3f2ab7ec2 154 Gene3D G3DSA:3.30.70.330 2 91 1.3E-5 T 28-03-2018 MKLM6_RS18945 c745aa2646e861d3fb61ac9823bd483e 184 PIRSF PIRSF038996 1 178 3.4E-49 T 28-03-2018 IPR010086 Flavodoxin, long chain GO:0010181 MKLM6_RS18945 c745aa2646e861d3fb61ac9823bd483e 184 Pfam PF00258 Flavodoxin 6 168 1.4E-19 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MKLM6_RS18945 c745aa2646e861d3fb61ac9823bd483e 184 TIGRFAM TIGR01752 flav_long: flavodoxin 3 176 6.5E-52 T 28-03-2018 IPR010086 Flavodoxin, long chain GO:0010181 MKLM6_RS18945 c745aa2646e861d3fb61ac9823bd483e 184 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 28-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 MKLM6_RS18945 c745aa2646e861d3fb61ac9823bd483e 184 SUPERFAMILY SSF52218 2 174 7.37E-37 T 28-03-2018 IPR029039 Flavoprotein-like domain MKLM6_RS18945 c745aa2646e861d3fb61ac9823bd483e 184 Gene3D G3DSA:3.40.50.360 3 177 1.3E-28 T 28-03-2018 IPR029039 Flavoprotein-like domain MKLM6_RS07140 9775453c5d71b50fdf0034847014d278 286 Pfam PF02666 Phosphatidylserine decarboxylase 65 282 3.2E-63 T 28-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 MKLM6_RS07140 9775453c5d71b50fdf0034847014d278 286 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 12 285 45.735 T 28-03-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 MKLM6_RS07140 9775453c5d71b50fdf0034847014d278 286 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 51 282 6.8E-78 T 28-03-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 MKLM6_RS15430 0bc56d2174945b79112791fd408da1da 257 SUPERFAMILY SSF55729 10 121 1.7E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS15430 0bc56d2174945b79112791fd408da1da 257 SUPERFAMILY SSF55729 149 206 1.7E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS15430 0bc56d2174945b79112791fd408da1da 257 TIGRFAM TIGR03694 exosort_acyl: N-acyl amino acid synthase, PEP-CTERM/exosortase system-associated 7 215 4.2E-51 T 28-03-2018 IPR022484 PEP-CTERM/exosortase system-associated acyltransferase, predicted MKLM6_RS15430 0bc56d2174945b79112791fd408da1da 257 Gene3D G3DSA:3.40.630.30 8 237 1.4E-39 T 28-03-2018 MKLM6_RS15430 0bc56d2174945b79112791fd408da1da 257 Pfam PF13444 Acetyltransferase (GNAT) domain 29 120 4.6E-15 T 28-03-2018 MKLM6_RS01815 0d62470d26129f673e9c33b37745f439 878 Pfam PF03699 Uncharacterised protein family (UPF0182) 14 794 5.3E-222 T 28-03-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 MKLM6_RS08805 bc7f3e856193fbac1fc6fb4d4f1dfe83 194 Pfam PF07238 PilZ domain 98 180 1.0E-6 T 28-03-2018 IPR009875 PilZ domain GO:0035438 MKLM6_RS08805 bc7f3e856193fbac1fc6fb4d4f1dfe83 194 Gene3D G3DSA:2.40.10.220 8 186 1.4E-15 T 28-03-2018 MKLM6_RS19900 f3849421998052d7870b80cc00bb8cac 96 Gene3D G3DSA:3.30.160.100 1 96 4.5E-31 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MKLM6_RS19900 f3849421998052d7870b80cc00bb8cac 96 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 92 1.6E-26 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MKLM6_RS19900 f3849421998052d7870b80cc00bb8cac 96 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 95 3.3E-33 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MKLM6_RS19900 f3849421998052d7870b80cc00bb8cac 96 SUPERFAMILY SSF69754 1 96 2.49E-34 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MKLM6_RS17420 c16e4b9c29778b9b702fe165bbe94073 215 Gene3D G3DSA:1.20.120.330 36 215 7.2E-6 T 28-03-2018 MKLM6_RS17420 c16e4b9c29778b9b702fe165bbe94073 215 Pfam PF11172 Protein of unknown function (DUF2959) 16 212 3.8E-88 T 28-03-2018 IPR021342 Protein of unknown function DUF2959 MKLM6_RS02815 0d56f412282ddf119b7a1c6688478e1a 283 Gene3D G3DSA:3.90.550.10 2 278 3.2E-41 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS02815 0d56f412282ddf119b7a1c6688478e1a 283 Pfam PF02709 N-terminal domain of galactosyltransferase 180 241 1.6E-14 T 28-03-2018 IPR027791 Galactosyltransferase, C-terminal Reactome: R-HSA-2022854|Reactome: R-HSA-975577 MKLM6_RS02815 0d56f412282ddf119b7a1c6688478e1a 283 SUPERFAMILY SSF53448 7 128 6.51E-42 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS02815 0d56f412282ddf119b7a1c6688478e1a 283 SUPERFAMILY SSF53448 179 258 6.51E-42 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS02815 0d56f412282ddf119b7a1c6688478e1a 283 Pfam PF00535 Glycosyl transferase family 2 9 109 1.6E-22 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MKLM6_RS17615 5403b806da3b2e7a4394e5b0aa83ad89 100 SUPERFAMILY SSF54909 1 98 1.0E-31 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel MKLM6_RS17615 5403b806da3b2e7a4394e5b0aa83ad89 100 Gene3D G3DSA:3.30.70.1060 1 98 1.9E-27 T 28-03-2018 MKLM6_RS17615 5403b806da3b2e7a4394e5b0aa83ad89 100 Pfam PF03795 YCII-related domain 1 95 2.7E-28 T 28-03-2018 IPR005545 YCII-related MKLM6_RS06215 8a601aae012522cf38ac7dc3ddf31e0a 86 Pfam PF04606 Ogr/Delta-like zinc finger 5 53 7.8E-13 T 28-03-2018 IPR007684 Zinc finger, Ogr/Delta-type MKLM6_RS19150 9c8dd372b55e5d255f4fe15480814515 250 Gene3D G3DSA:1.20.1450.10 29 243 1.4E-92 T 28-03-2018 IPR003393 Ammonia monooxygenase/particulate methane monooxygenase, subunit A MKLM6_RS19150 9c8dd372b55e5d255f4fe15480814515 250 Pfam PF02461 Ammonia monooxygenase 15 248 3.2E-109 T 28-03-2018 IPR003393 Ammonia monooxygenase/particulate methane monooxygenase, subunit A MKLM6_RS10100 9c675569b29f2ef6439e171780a9a705 205 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 31 4.6E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS10100 9c675569b29f2ef6439e171780a9a705 205 Gene3D G3DSA:3.30.700.10 11 169 1.5E-20 T 28-03-2018 MKLM6_RS10100 9c675569b29f2ef6439e171780a9a705 205 Pfam PF07963 Prokaryotic N-terminal methylation motif 10 30 9.6E-5 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site MKLM6_RS10100 9c675569b29f2ef6439e171780a9a705 205 Pfam PF12019 Type II transport protein GspH 46 176 7.2E-20 T 28-03-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 MKLM6_RS10100 9c675569b29f2ef6439e171780a9a705 205 SUPERFAMILY SSF54523 11 142 6.12E-21 T 28-03-2018 MKLM6_RS10100 9c675569b29f2ef6439e171780a9a705 205 TIGRFAM TIGR01708 typeII_sec_gspH: type II secretion system protein H 10 78 2.7E-13 T 28-03-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 MKLM6_RS15230 5c62bb449a34b069873d341bfc2ed427 366 Gene3D G3DSA:1.20.1250.20 4 357 8.3E-4 T 28-03-2018 MKLM6_RS15230 5c62bb449a34b069873d341bfc2ed427 366 PIRSF PIRSF031773 1 365 1.5E-57 T 28-03-2018 IPR005891 DevC protein MKLM6_RS15230 5c62bb449a34b069873d341bfc2ed427 366 Pfam PF02687 FtsX-like permease family 276 361 2.1E-7 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MKLM6_RS09100 84ad3614cb748aa34824f0be754cbe06 188 Gene3D G3DSA:3.40.1160.10 2 147 3.1E-5 T 28-03-2018 MKLM6_RS09100 84ad3614cb748aa34824f0be754cbe06 188 SUPERFAMILY SSF53633 2 141 6.55E-10 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MKLM6_RS09100 84ad3614cb748aa34824f0be754cbe06 188 Pfam PF00696 Amino acid kinase family 1 142 2.3E-8 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MKLM6_RS07105 630bbf1b5dc48fd9b884ba047fce87f7 217 SUPERFAMILY SSF48452 93 192 7.01E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS07105 630bbf1b5dc48fd9b884ba047fce87f7 217 PIRSF PIRSF006170 1 211 7.1E-61 T 28-03-2018 IPR026039 Uncharacterised protein family UPF0070 MKLM6_RS07105 630bbf1b5dc48fd9b884ba047fce87f7 217 Pfam PF09976 Tetratricopeptide repeat-like domain 15 207 1.7E-59 T 28-03-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 MKLM6_RS07105 630bbf1b5dc48fd9b884ba047fce87f7 217 Gene3D G3DSA:1.25.40.10 36 203 3.7E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS14240 48c857eca6d311e50ce32d0e6295a240 759 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 289 737 3.2E-59 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS14240 48c857eca6d311e50ce32d0e6295a240 759 Gene3D G3DSA:1.20.210.10 281 756 1.3E-52 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS14240 48c857eca6d311e50ce32d0e6295a240 759 SUPERFAMILY SSF81442 287 741 2.49E-58 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS15435 4abbaeb24fa15fba2fa046aa387f8dcf 1103 SUPERFAMILY SSF54001 8 338 1.11E-73 T 28-03-2018 MKLM6_RS15435 4abbaeb24fa15fba2fa046aa387f8dcf 1103 SMART SM00460 172 248 2.4E-18 T 28-03-2018 IPR002931 Transglutaminase-like MKLM6_RS15435 4abbaeb24fa15fba2fa046aa387f8dcf 1103 Pfam PF01841 Transglutaminase-like superfamily 142 246 8.0E-18 T 28-03-2018 IPR002931 Transglutaminase-like MKLM6_RS15435 4abbaeb24fa15fba2fa046aa387f8dcf 1103 Gene3D G3DSA:3.90.260.10 150 287 3.7E-6 T 28-03-2018 IPR002931 Transglutaminase-like MKLM6_RS15435 4abbaeb24fa15fba2fa046aa387f8dcf 1103 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 6 83 7.4E-28 T 28-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal MKLM6_RS15435 4abbaeb24fa15fba2fa046aa387f8dcf 1103 Pfam PF09899 Putative amidoligase enzyme (DUF2126) 278 1099 0.0 T 28-03-2018 IPR018667 Domain of unknown function DUF2126 MKLM6_RS05110 eddcf3dedbdc23de48cfa001ebe2938a 152 Gene3D G3DSA:3.30.310.70 24 150 1.1E-24 T 28-03-2018 IPR005180 Domain of unknown function DUF302 MKLM6_RS05110 eddcf3dedbdc23de48cfa001ebe2938a 152 Pfam PF03625 Domain of unknown function DUF302 63 119 7.0E-13 T 28-03-2018 IPR005180 Domain of unknown function DUF302 MKLM6_RS05110 eddcf3dedbdc23de48cfa001ebe2938a 152 SUPERFAMILY SSF103247 27 147 2.22E-25 T 28-03-2018 IPR005180 Domain of unknown function DUF302 MKLM6_RS10490 b22b5a906176ae09ae15fb04d59df04f 61 Pfam PF10055 Uncharacterized small protein (DUF2292) 19 53 1.2E-17 T 28-03-2018 IPR018743 Protein of unknown function DUF2292 MKLM6_RS11180 a393056ce2bfce5fa0b0756fc2cd0337 152 SUPERFAMILY SSF88697 1 151 1.24E-63 T 28-03-2018 IPR015947 PUA-like domain MKLM6_RS11180 a393056ce2bfce5fa0b0756fc2cd0337 152 Pfam PF01878 EVE domain 2 150 1.2E-59 T 28-03-2018 IPR002740 EVE domain MKLM6_RS11180 a393056ce2bfce5fa0b0756fc2cd0337 152 Gene3D G3DSA:3.10.590.10 1 152 1.9E-65 T 28-03-2018 MKLM6_RS05450 54263a30d1b8b3d401636d1fe279ad64 481 Pfam PF05787 Bacterial protein of unknown function (DUF839) 177 440 6.4E-14 T 28-03-2018 IPR008557 Protein of unknown function DUF839 MKLM6_RS05450 54263a30d1b8b3d401636d1fe279ad64 481 Gene3D G3DSA:2.120.10.30 260 447 1.8E-6 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MKLM6_RS05450 54263a30d1b8b3d401636d1fe279ad64 481 Gene3D G3DSA:2.120.10.30 63 224 0.18 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MKLM6_RS05450 54263a30d1b8b3d401636d1fe279ad64 481 SUPERFAMILY SSF63829 188 389 1.63E-8 T 28-03-2018 MKLM6_RS04695 313627ba6cbad855386f0a814f2fd3cc 217 Gene3D G3DSA:3.40.30.10 1 217 1.2E-19 T 28-03-2018 MKLM6_RS04695 313627ba6cbad855386f0a814f2fd3cc 217 SUPERFAMILY SSF52833 5 77 4.49E-14 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS04695 313627ba6cbad855386f0a814f2fd3cc 217 SUPERFAMILY SSF52833 150 208 4.49E-14 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS04695 313627ba6cbad855386f0a814f2fd3cc 217 Pfam PF00578 AhpC/TSA family 5 74 7.1E-5 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MKLM6_RS21025 09fb71e6f7bfe0c01c15b06b52a8dc40 321 PIRSF PIRSF018266 6 318 3.8E-85 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component MKLM6_RS21025 09fb71e6f7bfe0c01c15b06b52a8dc40 321 Pfam PF04773 FecR protein 112 203 2.0E-21 T 28-03-2018 IPR006860 FecR protein MKLM6_RS21025 09fb71e6f7bfe0c01c15b06b52a8dc40 321 Pfam PF16220 Domain of unknown function (DUF4880) 15 56 1.4E-14 T 28-03-2018 IPR032623 FecR, N-terminal MKLM6_RS18680 f51dd1bfc29ec32f423084fc68780be7 388 Pfam PF03929 PepSY-associated TM region 20 375 3.8E-67 T 28-03-2018 IPR005625 PepSY-associated TM protein MKLM6_RS18680 f51dd1bfc29ec32f423084fc68780be7 388 Gene3D G3DSA:1.20.950.20 155 385 0.0018 T 28-03-2018 MKLM6_RS18680 f51dd1bfc29ec32f423084fc68780be7 388 Pfam PF03413 Peptidase propeptide and YPEB domain 259 320 2.9E-4 T 28-03-2018 IPR025711 PepSY domain MKLM6_RS02015 a3d9068b3cba77bf7a72fc692a585f03 467 SUPERFAMILY SSF56954 11 466 3.53E-86 T 28-03-2018 MKLM6_RS02015 a3d9068b3cba77bf7a72fc692a585f03 467 Gene3D G3DSA:1.20.1600.10 20 467 1.2E-78 T 28-03-2018 MKLM6_RS02015 a3d9068b3cba77bf7a72fc692a585f03 467 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 15 465 1.0E-85 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 MKLM6_RS02015 a3d9068b3cba77bf7a72fc692a585f03 467 Pfam PF02321 Outer membrane efflux protein 282 464 1.3E-18 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS02015 a3d9068b3cba77bf7a72fc692a585f03 467 Pfam PF02321 Outer membrane efflux protein 66 247 7.3E-21 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS17085 9c880172dfc4a3eac82b800102b581cb 597 Pfam PF04932 O-Antigen ligase 196 332 7.6E-11 T 28-03-2018 IPR007016 O-antigen ligase-related MKLM6_RS17085 9c880172dfc4a3eac82b800102b581cb 597 Pfam PF11846 Virulence factor membrane-bound polymerase, C-terminal 372 550 9.6E-23 T 28-03-2018 IPR021797 Virulence factor membrane-bound polymerase, C-terminal MKLM6_RS04540 36d32b56ffc0454f22677d0bbe84d055 430 Pfam PF02321 Outer membrane efflux protein 225 406 9.2E-31 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS04540 36d32b56ffc0454f22677d0bbe84d055 430 Pfam PF02321 Outer membrane efflux protein 14 203 2.1E-16 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS04540 36d32b56ffc0454f22677d0bbe84d055 430 Gene3D G3DSA:1.20.1600.10 2 418 2.1E-61 T 28-03-2018 MKLM6_RS04540 36d32b56ffc0454f22677d0bbe84d055 430 SUPERFAMILY SSF56954 12 418 3.27E-78 T 28-03-2018 MKLM6_RS04540 36d32b56ffc0454f22677d0bbe84d055 430 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 10 423 3.2E-96 T 28-03-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 MKLM6_RS02360 bdbd8f856348e811a1ae31457798a48f 118 Pfam PF10387 Protein of unknown function (DUF2442) 5 77 2.7E-20 T 28-03-2018 IPR018841 Protein of unknown function DUF2442 MKLM6_RS02360 bdbd8f856348e811a1ae31457798a48f 118 Gene3D G3DSA:3.30.2020.10 1 80 4.2E-24 T 28-03-2018 IPR018841 Protein of unknown function DUF2442 MKLM6_RS02360 bdbd8f856348e811a1ae31457798a48f 118 SUPERFAMILY SSF143880 1 81 2.09E-23 T 28-03-2018 IPR018841 Protein of unknown function DUF2442 MKLM6_RS17760 b3c8b12dff905003ec03796414216249 599 Pfam PF04326 Putative DNA-binding domain 429 585 3.1E-7 T 28-03-2018 IPR007421 Schlafen, AAA domain GO:0005524 MKLM6_RS17760 b3c8b12dff905003ec03796414216249 599 Pfam PF03235 Protein of unknown function DUF262 32 172 1.6E-16 T 28-03-2018 IPR004919 Domain of unknown function DUF262 MKLM6_RS18015 1b9704e0d31a4364f6da98fa37dfa677 147 SUPERFAMILY SSF160214 49 137 3.14E-22 T 28-03-2018 IPR005186 FlaG protein MKLM6_RS18015 1b9704e0d31a4364f6da98fa37dfa677 147 Gene3D G3DSA:3.30.160.170 41 138 7.0E-24 T 28-03-2018 IPR005186 FlaG protein MKLM6_RS18015 1b9704e0d31a4364f6da98fa37dfa677 147 Pfam PF03646 FlaG protein 48 137 1.9E-23 T 28-03-2018 IPR005186 FlaG protein MKLM6_RS12995 36f79f6458b9c5544c3288b42f3e6c9c 258 SUPERFAMILY SSF88713 24 212 3.25E-37 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MKLM6_RS12995 36f79f6458b9c5544c3288b42f3e6c9c 258 Pfam PF01522 Polysaccharide deacetylase 55 191 3.0E-27 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MKLM6_RS12995 36f79f6458b9c5544c3288b42f3e6c9c 258 Gene3D G3DSA:3.20.20.370 13 247 1.4E-47 T 28-03-2018 MKLM6_RS22645 fa1d3b061c3647ba092103d7b193db6d 208 SUPERFAMILY SSF159941 20 194 5.49E-52 T 28-03-2018 IPR024047 Protein MM3350-like domain MKLM6_RS22645 fa1d3b061c3647ba092103d7b193db6d 208 Gene3D G3DSA:3.10.290.30 13 195 3.7E-53 T 28-03-2018 IPR024047 Protein MM3350-like domain MKLM6_RS22645 fa1d3b061c3647ba092103d7b193db6d 208 Pfam PF07929 Plasmid pRiA4b ORF-3-like protein 21 190 7.9E-53 T 28-03-2018 IPR012912 Plasmid pRiA4b, Orf3 MKLM6_RS17920 9e21404a1047e73025a31aaf5ad2f6f4 737 Pfam PF04632 Fusaric acid resistance protein family 76 563 7.2E-14 T 28-03-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 MKLM6_RS05230 cac6cd21857bd3bd1ae320adcf670330 70 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 12 59 3.0E-5 T 28-03-2018 IPR010260 DNA-binding transcriptional activator AlpA MKLM6_RS06960 3362da53c1cdf62b5d27552543b84bb0 89 Pfam PF07510 Protein of unknown function (DUF1524) 14 75 8.2E-6 T 28-03-2018 IPR011089 Domain of unknown function DUF1524 MKLM6_RS01840 f7eb16ce188b91f79488bf1d56658429 196 Pfam PF13511 Domain of unknown function (DUF4124) 9 61 4.1E-7 T 28-03-2018 IPR025392 Domain of unknown function DUF4124 MKLM6_RS00690 66c5c7d476cea6e2ebf329762d416411 333 Gene3D G3DSA:3.20.20.80 41 318 1.3E-22 T 28-03-2018 MKLM6_RS00690 66c5c7d476cea6e2ebf329762d416411 333 SUPERFAMILY SSF51445 55 316 1.16E-27 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily MKLM6_RS14260 f983e110591865c44d603be1382d9cbc 179 Gene3D G3DSA:1.10.150.130 34 170 0.0012 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal MKLM6_RS12050 1e55ab1bae604c7869a7185483dca047 178 SUPERFAMILY SSF52540 3 170 9.65E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS12050 1e55ab1bae604c7869a7185483dca047 178 Gene3D G3DSA:3.40.50.300 1 174 1.7E-20 T 28-03-2018 MKLM6_RS12050 1e55ab1bae604c7869a7185483dca047 178 Pfam PF03029 Conserved hypothetical ATP binding protein 29 128 1.5E-7 T 28-03-2018 IPR004130 GPN-loop GTPase MKLM6_RS07500 c030e02528f567688a5eb97df20f598b 240 SUPERFAMILY SSF140931 67 238 1.12E-45 T 28-03-2018 IPR003812 Fido domain MKLM6_RS07500 c030e02528f567688a5eb97df20f598b 240 Gene3D G3DSA:1.10.3290.10 1 239 1.4E-67 T 28-03-2018 IPR003812 Fido domain MKLM6_RS07500 c030e02528f567688a5eb97df20f598b 240 Pfam PF02661 Fic/DOC family 91 184 1.3E-24 T 28-03-2018 IPR003812 Fido domain MKLM6_RS08395 e04d68ea8884605f0b009687343be10b 163 Pfam PF04982 HPP family 49 156 1.0E-31 T 28-03-2018 IPR007065 HPP MKLM6_RS22180 8e42584410ae1d27e168f80cda3c0ed0 71 Pfam PF14454 Prokaryotic Ubiquitin 7 64 5.3E-11 T 28-03-2018 IPR032866 Prokaryotic Ubiquitin MKLM6_RS02545 e8743040cef7feab27444591eb43cbed 265 Pfam PF04116 Fatty acid hydroxylase superfamily 85 216 1.6E-25 T 28-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 MKLM6_RS07600 d69d58e831033667b65649819d5b9c55 187 Pfam PF09721 Transmembrane exosortase (Exosortase_EpsH) 57 172 2.0E-7 T 28-03-2018 IPR019127 Exosortase EpsH-related MKLM6_RS07600 d69d58e831033667b65649819d5b9c55 187 TIGRFAM TIGR04300 exosort_XrtM: exosortase family protein XrtM 34 178 1.1E-46 T 28-03-2018 IPR027567 Exosortase XrtM MKLM6_RS07600 d69d58e831033667b65649819d5b9c55 187 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 87 175 5.3E-16 T 28-03-2018 IPR026392 Exosortase/Archaeosortase domain MKLM6_RS17385 a81c0b090e7ad07f7ac559633534f585 73 Pfam PF06988 NifT/FixU protein 1 67 6.9E-24 T 28-03-2018 IPR009727 NifT/FixU GO:0009399 MKLM6_RS17385 a81c0b090e7ad07f7ac559633534f585 73 SUPERFAMILY SSF159203 3 70 2.62E-19 T 28-03-2018 IPR024044 NifT/FixU barrel-like domain MKLM6_RS17385 a81c0b090e7ad07f7ac559633534f585 73 Gene3D G3DSA:2.40.50.240 3 70 2.8E-26 T 28-03-2018 IPR024044 NifT/FixU barrel-like domain MKLM6_RS17385 a81c0b090e7ad07f7ac559633534f585 73 TIGRFAM TIGR02934 nifT_nitrog: probable nitrogen fixation protein FixT 4 70 2.2E-20 T 28-03-2018 IPR009727 NifT/FixU GO:0009399 MKLM6_RS03755 54855ce91ce632b5e0ae29c9c9cdfa5f 102 SUPERFAMILY SSF46626 11 99 1.19E-18 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS03755 54855ce91ce632b5e0ae29c9c9cdfa5f 102 Gene3D G3DSA:1.10.760.10 9 100 3.8E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS03755 54855ce91ce632b5e0ae29c9c9cdfa5f 102 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 29 96 1.5E-7 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS10290 af59fcabb89a67b072f213a81c1edfcf 198 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 6 168 26.207 T 28-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 MKLM6_RS10290 af59fcabb89a67b072f213a81c1edfcf 198 Pfam PF03975 CheD chemotactic sensory transduction 69 164 4.2E-26 T 28-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 MKLM6_RS10290 af59fcabb89a67b072f213a81c1edfcf 198 SUPERFAMILY SSF64438 11 169 7.14E-43 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic MKLM6_RS16185 1b9699d29b1fbf08bedbbdf39da71d90 511 SUPERFAMILY SSF51735 379 506 4.19E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS16185 1b9699d29b1fbf08bedbbdf39da71d90 511 Gene3D G3DSA:3.40.50.720 377 508 2.0E-17 T 28-03-2018 MKLM6_RS16185 1b9699d29b1fbf08bedbbdf39da71d90 511 Pfam PF02254 TrkA-N domain 380 494 2.3E-21 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MKLM6_RS16185 1b9699d29b1fbf08bedbbdf39da71d90 511 Pfam PF00999 Sodium/hydrogen exchanger family 4 338 3.8E-30 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MKLM6_RS02910 86456e2613b60aab0ddb2449c8ed0cb4 443 SUPERFAMILY SSF111283 10 443 1.01E-129 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 MKLM6_RS02910 86456e2613b60aab0ddb2449c8ed0cb4 443 Pfam PF01523 Putative modulator of DNA gyrase 29 320 3.2E-60 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 MKLM6_RS02910 86456e2613b60aab0ddb2449c8ed0cb4 443 Gene3D G3DSA:3.30.2290.10 1 229 5.6E-63 T 28-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain MKLM6_RS00235 01378c801a2374b4b26a496737b8aa93 250 Pfam PF01863 Protein of unknown function DUF45 39 243 2.1E-53 T 28-03-2018 IPR002725 Protein of unknown function DUF45 MKLM6_RS15865 9477dca53fbd4fdbb53bd65375a52033 182 SUPERFAMILY SSF51182 1 179 1.48E-78 T 28-03-2018 IPR011051 RmlC-like cupin domain MKLM6_RS15865 9477dca53fbd4fdbb53bd65375a52033 182 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 176 3.9E-74 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MKLM6_RS15865 9477dca53fbd4fdbb53bd65375a52033 182 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 181 3.0E-77 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MKLM6_RS15865 9477dca53fbd4fdbb53bd65375a52033 182 Gene3D G3DSA:2.60.120.10 1 181 8.1E-76 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS15865 9477dca53fbd4fdbb53bd65375a52033 182 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 4 179 2.1E-83 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MKLM6_RS13170 a1336aad6f15801de6b7f1094961610f 415 Pfam PF00872 Transposase, Mutator family 13 375 4.2E-67 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS08580 40e4144ab61392894fff5213c10069b7 809 Pfam PF07940 Heparinase II/III-like protein 413 624 3.8E-5 T 28-03-2018 IPR012480 Heparinase II/III-like GO:0016829 MKLM6_RS08580 40e4144ab61392894fff5213c10069b7 809 SUPERFAMILY SSF48230 120 320 3.84E-8 T 28-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 MKLM6_RS10640 b083d6a21c7b92027af13748a0b87203 168 Pfam PF03872 Anti sigma-E protein RseA, N-terminal domain 6 81 1.7E-11 T 28-03-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 MKLM6_RS10640 b083d6a21c7b92027af13748a0b87203 168 SUPERFAMILY SSF89069 6 72 6.15E-9 T 28-03-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 MKLM6_RS20150 576f224e23b0eb767bdf06206cc7de90 406 Pfam PF00999 Sodium/hydrogen exchanger family 13 399 7.8E-47 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MKLM6_RS18780 904b1417852d5e3df3f2e8d1f5f77156 131 PIRSF PIRSF002889 1 131 6.0E-43 T 28-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 MKLM6_RS18780 904b1417852d5e3df3f2e8d1f5f77156 131 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 15 35 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site MKLM6_RS18780 904b1417852d5e3df3f2e8d1f5f77156 131 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 5 129 2.5E-34 T 28-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 MKLM6_RS18780 904b1417852d5e3df3f2e8d1f5f77156 131 Pfam PF00460 Flagella basal body rod protein 14 39 3.7E-5 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 MKLM6_RS21610 516d644659ee515fb2777b380f8974ed 183 Gene3D G3DSA:3.40.50.10070 58 175 2.1E-9 T 28-03-2018 MKLM6_RS07275 57fe74666ff6bef10cda34094e263bf8 241 Gene3D G3DSA:3.90.550.10 1 231 1.6E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS07275 57fe74666ff6bef10cda34094e263bf8 241 SUPERFAMILY SSF53448 1 208 1.13E-39 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS07275 57fe74666ff6bef10cda34094e263bf8 241 Pfam PF00535 Glycosyl transferase family 2 4 166 4.1E-25 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MKLM6_RS16460 2501262c34439de0202b335438223fc5 337 SUPERFAMILY SSF52540 2 209 9.92E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS16460 2501262c34439de0202b335438223fc5 337 Pfam PF06144 DNA polymerase III, delta subunit 20 188 7.8E-31 T 28-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 MKLM6_RS16460 2501262c34439de0202b335438223fc5 337 Pfam PF14840 Processivity clamp loader gamma complex DNA pol III C-term 214 329 7.9E-16 T 28-03-2018 IPR032780 DNA polymerase III subunit delta, C-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MKLM6_RS16460 2501262c34439de0202b335438223fc5 337 Gene3D G3DSA:3.40.50.300 1 139 1.8E-20 T 28-03-2018 MKLM6_RS16460 2501262c34439de0202b335438223fc5 337 Gene3D G3DSA:1.20.272.10 220 336 2.8E-31 T 28-03-2018 MKLM6_RS16460 2501262c34439de0202b335438223fc5 337 SUPERFAMILY SSF48019 211 333 3.74E-30 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MKLM6_RS16460 2501262c34439de0202b335438223fc5 337 Gene3D G3DSA:1.10.8.60 142 219 3.9E-23 T 28-03-2018 MKLM6_RS16460 2501262c34439de0202b335438223fc5 337 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 17 331 2.5E-92 T 28-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 MKLM6_RS10955 a8a5d474c3bd7a8a398799732657cfa3 326 PRINTS PR01270 Histone deacetylase superfamily signature 157 172 3.1E-16 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MKLM6_RS10955 a8a5d474c3bd7a8a398799732657cfa3 326 PRINTS PR01270 Histone deacetylase superfamily signature 123 146 3.1E-16 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MKLM6_RS10955 a8a5d474c3bd7a8a398799732657cfa3 326 PRINTS PR01270 Histone deacetylase superfamily signature 237 247 3.1E-16 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MKLM6_RS10955 a8a5d474c3bd7a8a398799732657cfa3 326 Gene3D G3DSA:3.40.800.20 1 321 5.1E-110 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MKLM6_RS10955 a8a5d474c3bd7a8a398799732657cfa3 326 SUPERFAMILY SSF52768 1 318 2.4E-101 T 28-03-2018 MKLM6_RS10955 a8a5d474c3bd7a8a398799732657cfa3 326 Pfam PF00850 Histone deacetylase domain 20 307 2.5E-83 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MKLM6_RS01165 95ddbb1dcd2a7000fe6651d5e54ff360 256 Gene3D G3DSA:3.40.50.150 25 254 2.6E-12 T 28-03-2018 MKLM6_RS01165 95ddbb1dcd2a7000fe6651d5e54ff360 256 SUPERFAMILY SSF53335 99 225 5.74E-15 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS01190 732825db50e6afd56cd6a4800abed256 275 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 265 17.46 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MKLM6_RS01190 732825db50e6afd56cd6a4800abed256 275 Pfam PF02673 Bacitracin resistance protein BacA 10 260 1.2E-81 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MKLM6_RS01190 732825db50e6afd56cd6a4800abed256 275 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 10 258 2.4E-72 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MKLM6_RS12600 7e7ca92b0fc29cce3f7703329c43034e 152 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 152 82.813 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 MKLM6_RS12600 7e7ca92b0fc29cce3f7703329c43034e 152 Pfam PF03477 ATP cone domain 50 136 1.5E-17 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 MKLM6_RS12600 7e7ca92b0fc29cce3f7703329c43034e 152 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 1.9E-63 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 MKLM6_RS07650 1c51652f7ca02274fde039dbe7612d61 390 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 9 376 3.0E-149 T 28-03-2018 IPR007434 Peptidogalycan biosysnthesis/recognition MKLM6_RS07650 1c51652f7ca02274fde039dbe7612d61 390 SUPERFAMILY SSF55729 177 351 2.44E-41 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS07650 1c51652f7ca02274fde039dbe7612d61 390 Gene3D G3DSA:3.40.630.30 184 336 8.1E-36 T 28-03-2018 MKLM6_RS07650 1c51652f7ca02274fde039dbe7612d61 390 Gene3D G3DSA:3.40.630.30 8 183 4.2E-13 T 28-03-2018 MKLM6_RS06920 9fc2fc9fc0310b44c86ce25d6287dbbb 302 Gene3D G3DSA:3.40.50.300 12 173 1.9E-26 T 28-03-2018 MKLM6_RS06920 9fc2fc9fc0310b44c86ce25d6287dbbb 302 PIRSF PIRSF006230 1 277 1.6E-96 T 28-03-2018 IPR016478 GTPase, MTG1 MKLM6_RS06920 9fc2fc9fc0310b44c86ce25d6287dbbb 302 Pfam PF01926 50S ribosome-binding GTPase 117 211 4.8E-15 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS06920 9fc2fc9fc0310b44c86ce25d6287dbbb 302 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 272 1.3E-101 T 28-03-2018 IPR019991 GTP-binding protein, ribosome biogenesis MKLM6_RS06920 9fc2fc9fc0310b44c86ce25d6287dbbb 302 SUPERFAMILY SSF52540 9 208 4.29E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS06920 9fc2fc9fc0310b44c86ce25d6287dbbb 302 Gene3D G3DSA:1.10.1580.10 174 275 3.1E-23 T 28-03-2018 IPR023179 GTP-binding protein, orthogonal bundle domain MKLM6_RS16660 91ee95f56d50128e7451381fc119a18a 134 Gene3D G3DSA:3.30.70.330 2 120 2.4E-6 T 28-03-2018 MKLM6_RS16660 91ee95f56d50128e7451381fc119a18a 134 SUPERFAMILY SSF54928 2 94 6.8E-8 T 28-03-2018 IPR000504 RNA recognition motif domain GO:0003676 MKLM6_RS20400 554260d6ce1e61dcc3c98b869fbcd04f 182 PIRSF PIRSF016481 6 180 2.0E-48 T 28-03-2018 IPR007446 Pilus assembly protein PilP MKLM6_RS20400 554260d6ce1e61dcc3c98b869fbcd04f 182 Pfam PF04351 Pilus assembly protein, PilP 29 176 1.7E-52 T 28-03-2018 IPR007446 Pilus assembly protein PilP MKLM6_RS20890 7bd79f972806d89f5e51e00b2a65acfe 382 Pfam PF07786 Protein of unknown function (DUF1624) 4 215 1.6E-16 T 28-03-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-6798695 MKLM6_RS19540 80d3950a221014797f414d0c38c4403a 330 Gene3D G3DSA:3.20.20.370 39 330 9.1E-15 T 28-03-2018 MKLM6_RS19540 80d3950a221014797f414d0c38c4403a 330 SUPERFAMILY SSF88713 46 244 9.85E-10 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MKLM6_RS10870 c989b8b1a9fd45172e914609e6e9246e 224 PIRSF PIRSF002764 1 224 4.1E-81 T 28-03-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria MKLM6_RS10870 c989b8b1a9fd45172e914609e6e9246e 224 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 10 220 1.4E-78 T 28-03-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria MKLM6_RS10870 c989b8b1a9fd45172e914609e6e9246e 224 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 105 123 1.5E-58 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10870 c989b8b1a9fd45172e914609e6e9246e 224 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 57 74 1.5E-58 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10870 c989b8b1a9fd45172e914609e6e9246e 224 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 80 103 1.5E-58 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10870 c989b8b1a9fd45172e914609e6e9246e 224 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 160 179 1.5E-58 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10870 c989b8b1a9fd45172e914609e6e9246e 224 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 197 220 1.5E-58 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10870 c989b8b1a9fd45172e914609e6e9246e 224 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 31 52 1.5E-58 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS10870 c989b8b1a9fd45172e914609e6e9246e 224 Pfam PF03379 CcmB protein 8 220 9.0E-79 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 MKLM6_RS17275 b3e1f7109c7168f40eb704bc76562099 93 SUPERFAMILY SSF53098 31 73 1.78E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS17275 b3e1f7109c7168f40eb704bc76562099 93 Gene3D G3DSA:3.30.420.10 31 89 3.3E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MKLM6_RS22570 4b9557be9845fa2dac146eb5fa8b2534 292 Pfam PF06586 TraK protein 50 273 2.2E-17 T 28-03-2018 IPR010563 Pilus assembly TraK MKLM6_RS01545 3df240364c93df3a92a47f07b469d64b 328 SMART SM00587 111 268 2.1E-4 T 28-03-2018 IPR015897 CHK kinase-like MKLM6_RS01545 3df240364c93df3a92a47f07b469d64b 328 SUPERFAMILY SSF56112 8 302 5.25E-25 T 28-03-2018 IPR011009 Protein kinase-like domain MKLM6_RS01545 3df240364c93df3a92a47f07b469d64b 328 Gene3D G3DSA:3.90.1200.10 70 301 2.1E-15 T 28-03-2018 MKLM6_RS01545 3df240364c93df3a92a47f07b469d64b 328 Pfam PF02958 Ecdysteroid kinase 169 267 2.9E-12 T 28-03-2018 IPR004119 Protein of unknown function DUF227 MKLM6_RS01545 3df240364c93df3a92a47f07b469d64b 328 Pfam PF02958 Ecdysteroid kinase 74 146 2.6E-4 T 28-03-2018 IPR004119 Protein of unknown function DUF227 MKLM6_RS02855 cad834462a3ed6233b6e71215e111024 90 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 26 87 1.6E-14 T 28-03-2018 IPR008792 Coenzyme PQQ synthesis D MKLM6_RS02855 cad834462a3ed6233b6e71215e111024 90 TIGRFAM TIGR03859 PQQ_PqqD: coenzyme PQQ biosynthesis protein PqqD 10 88 4.2E-28 T 28-03-2018 IPR022479 Coenzyme PQQ synthesis D, bacteria GO:0018189|GO:0048038 MKLM6_RS09310 bef8044b1f0612b8a3d4abae7a0d4d5d 415 Pfam PF01943 Polysaccharide biosynthesis protein 8 273 2.0E-15 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 MKLM6_RS09310 bef8044b1f0612b8a3d4abae7a0d4d5d 415 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 330 404 7.4E-7 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain MKLM6_RS20855 94a5ebf29f710e761bd2732e0d542184 252 Pfam PF09836 Putative DNA-binding domain 8 93 2.4E-26 T 28-03-2018 IPR018640 Putative DNA-binding domain, bacteria MKLM6_RS04315 64a40e94ed17a0db8218c55e42d22e84 156 Gene3D G3DSA:1.10.10.10 16 72 4.4E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS12425 2a2ccf9b03325242378c88b4a9a3152a 219 SUPERFAMILY SSF53335 50 202 2.28E-21 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS12425 2a2ccf9b03325242378c88b4a9a3152a 219 Pfam PF13489 Methyltransferase domain 66 200 2.1E-17 T 28-03-2018 MKLM6_RS12425 2a2ccf9b03325242378c88b4a9a3152a 219 Gene3D G3DSA:3.40.50.150 34 108 0.0016 T 28-03-2018 MKLM6_RS12425 2a2ccf9b03325242378c88b4a9a3152a 219 Gene3D G3DSA:3.40.50.150 109 216 1.1E-8 T 28-03-2018 MKLM6_RS03095 82b9a76dcf31857bb1175d712ee0f972 362 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 7 360 2.7E-59 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MKLM6_RS03095 82b9a76dcf31857bb1175d712ee0f972 362 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 1 341 1.6E-80 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MKLM6_RS08095 3fc7e71fab7eba8ac28148918909ca61 332 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 30 305 3.9E-17 T 28-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD MKLM6_RS08095 3fc7e71fab7eba8ac28148918909ca61 332 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 13 311 5.1E-31 T 28-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD MKLM6_RS10005 7f4390030a54a064ef12baf73a6020fd 382 Gene3D G3DSA:3.40.50.2300 1 368 9.2E-36 T 28-03-2018 MKLM6_RS10005 7f4390030a54a064ef12baf73a6020fd 382 SMART SM00448 6 117 9.8E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS10005 7f4390030a54a064ef12baf73a6020fd 382 Pfam PF00072 Response regulator receiver domain 8 117 4.7E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS10005 7f4390030a54a064ef12baf73a6020fd 382 SUPERFAMILY SSF52172 5 157 2.85E-32 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS06855 7ea7ad4847868ff6c5c2f7d489f84e65 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 16.352 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS06855 7ea7ad4847868ff6c5c2f7d489f84e65 60 SUPERFAMILY SSF57829 2 54 1.83E-16 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 MKLM6_RS06855 7ea7ad4847868ff6c5c2f7d489f84e65 60 Pfam PF01783 Ribosomal L32p protein family 2 54 2.0E-18 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS06855 7ea7ad4847868ff6c5c2f7d489f84e65 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 54 3.0E-17 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MKLM6_RS07835 a9d00970340fd394574fcb61ab3fda54 94 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 22 81 1.5E-6 T 28-03-2018 IPR012933 HicA mRNA interferase family GO:0003729 MKLM6_RS07445 eec81a8becdf799a8c81605f04edb8c8 805 Pfam PF13148 Protein of unknown function (DUF3987) 355 723 2.2E-93 T 28-03-2018 IPR025048 Protein of unknown function DUF3987) MKLM6_RS07445 eec81a8becdf799a8c81605f04edb8c8 805 Pfam PF13362 Toprim domain 198 296 7.7E-11 T 28-03-2018 IPR006171 TOPRIM domain MKLM6_RS07445 eec81a8becdf799a8c81605f04edb8c8 805 Gene3D G3DSA:3.40.1360.10 185 309 8.0E-15 T 28-03-2018 MKLM6_RS07445 eec81a8becdf799a8c81605f04edb8c8 805 SMART SM00493 196 275 0.0095 T 28-03-2018 IPR006171 TOPRIM domain MKLM6_RS04495 d5c6da2cd0038b4e64f8dbd751a9583b 201 Gene3D G3DSA:3.90.1570.10 6 198 2.5E-43 T 28-03-2018 MKLM6_RS04495 d5c6da2cd0038b4e64f8dbd751a9583b 201 SUPERFAMILY SSF52980 12 198 1.93E-36 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MKLM6_RS04495 d5c6da2cd0038b4e64f8dbd751a9583b 201 Pfam PF05685 Putative restriction endonuclease 20 194 2.1E-28 T 28-03-2018 IPR008538 Domain of unknown function DUF820 MKLM6_RS02240 6ab22e5f01539044ae20f6896d52b055 1268 Pfam PF13502 AsmA-like C-terminal region 1000 1237 2.3E-42 T 28-03-2018 IPR032712 AsmA-like, C-terminal MKLM6_RS02240 6ab22e5f01539044ae20f6896d52b055 1268 TIGRFAM TIGR02099 TIGR02099: TIGR02099 family protein 14 1246 3.3E-194 T 28-03-2018 IPR011836 Conserved hypothetical protein CHP02099 MKLM6_RS02240 6ab22e5f01539044ae20f6896d52b055 1268 Pfam PF13116 Protein of unknown function 506 783 1.6E-52 T 28-03-2018 IPR025263 Domain of unknown function DUF3971 MKLM6_RS14205 0c70c4f7e7c1889c2bd3d1d12389c05e 259 PIRSF PIRSF018982 1 249 5.2E-87 T 28-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 MKLM6_RS14205 0c70c4f7e7c1889c2bd3d1d12389c05e 259 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 5 240 2.9E-85 T 28-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 MKLM6_RS14645 2c05eb2fd979bd89c9221ea666a6c8a1 259 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 3 258 7.0E-81 T 28-03-2018 MKLM6_RS14645 2c05eb2fd979bd89c9221ea666a6c8a1 259 Pfam PF01875 Memo-like protein 5 256 4.7E-55 T 28-03-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 MKLM6_RS14645 2c05eb2fd979bd89c9221ea666a6c8a1 259 Hamap MF_00055 MEMO1 family protein . 1 259 49.091 T 28-03-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 MKLM6_RS14645 2c05eb2fd979bd89c9221ea666a6c8a1 259 Gene3D G3DSA:3.40.830.10 5 230 3.4E-27 T 28-03-2018 MKLM6_RS09550 d784d05275db2996319b412024735e9e 360 Pfam PF06472 ABC transporter transmembrane region 2 7 293 2.3E-33 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MKLM6_RS09550 d784d05275db2996319b412024735e9e 360 SUPERFAMILY SSF90123 27 343 5.76E-16 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MKLM6_RS09550 d784d05275db2996319b412024735e9e 360 Gene3D G3DSA:1.20.1560.10 6 351 1.0E-23 T 28-03-2018 MKLM6_RS12610 4132467201d5b66f0217d17755da4be1 217 SMART SM01007 34 210 0.0027 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal MKLM6_RS12610 4132467201d5b66f0217d17755da4be1 217 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 52 201 9.1E-12 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal MKLM6_RS12610 4132467201d5b66f0217d17755da4be1 217 Gene3D G3DSA:3.40.225.10 20 204 4.1E-18 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal MKLM6_RS12610 4132467201d5b66f0217d17755da4be1 217 SUPERFAMILY SSF53639 49 201 2.16E-14 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal MKLM6_RS14575 fe3002d844181f0748348f563d148f38 436 SUPERFAMILY SSF52540 1 331 1.81E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS14575 fe3002d844181f0748348f563d148f38 436 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 26 328 5.5E-24 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MKLM6_RS14575 fe3002d844181f0748348f563d148f38 436 Gene3D G3DSA:3.40.50.300 1 345 9.1E-31 T 28-03-2018 MKLM6_RS07660 3ecee0e8ce117e39d77178e2aa8a56d2 168 Pfam PF01863 Protein of unknown function DUF45 93 154 6.6E-11 T 28-03-2018 IPR002725 Protein of unknown function DUF45 MKLM6_RS15870 a40ba21cae3ab2509b43444e32eccb7d 176 Gene3D G3DSA:1.20.120.330 1 148 5.8E-15 T 28-03-2018 MKLM6_RS15870 a40ba21cae3ab2509b43444e32eccb7d 176 SUPERFAMILY SSF81593 54 128 9.42E-12 T 28-03-2018 MKLM6_RS10615 211a9416b53db710f36e5fe42554c172 245 PIRSF PIRSF002859 2 245 1.1E-58 T 28-03-2018 IPR008874 Enterobacterial TraT complement resistance GO:0019867|GO:0046999 MKLM6_RS10615 211a9416b53db710f36e5fe42554c172 245 Pfam PF05818 Enterobacterial TraT complement resistance protein 27 245 4.1E-76 T 28-03-2018 IPR008874 Enterobacterial TraT complement resistance GO:0019867|GO:0046999 MKLM6_RS10070 8a705a0f9483b6d19877043122a0ba8e 339 Pfam PF02547 Queuosine biosynthesis protein 4 338 6.7E-129 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MKLM6_RS10070 8a705a0f9483b6d19877043122a0ba8e 339 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 339 46.421 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MKLM6_RS10070 8a705a0f9483b6d19877043122a0ba8e 339 Gene3D G3DSA:3.40.1780.10 1 123 4.0E-29 T 28-03-2018 MKLM6_RS10070 8a705a0f9483b6d19877043122a0ba8e 339 Gene3D G3DSA:3.40.1780.10 172 339 2.0E-64 T 28-03-2018 MKLM6_RS10070 8a705a0f9483b6d19877043122a0ba8e 339 SUPERFAMILY SSF111337 4 338 1.01E-132 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MKLM6_RS10070 8a705a0f9483b6d19877043122a0ba8e 339 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 339 4.5E-133 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MKLM6_RS12720 893e23ccfe8d70d6ee33749c9e4c790c 334 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 8 329 40.672 T 28-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 MKLM6_RS12720 893e23ccfe8d70d6ee33749c9e4c790c 334 Gene3D G3DSA:3.40.50.300 53 176 3.6E-9 T 28-03-2018 MKLM6_RS12720 893e23ccfe8d70d6ee33749c9e4c790c 334 SUPERFAMILY SSF52540 53 204 3.83E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS12720 893e23ccfe8d70d6ee33749c9e4c790c 334 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 26 329 1.1E-87 T 28-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 MKLM6_RS12720 893e23ccfe8d70d6ee33749c9e4c790c 334 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 20 328 1.4E-113 T 28-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 MKLM6_RS06185 1e3496172494263df693f2ff75b0820b 97 Pfam PF10554 Ash protein family 45 87 4.0E-5 T 28-03-2018 IPR018880 Bacteriophage P4, Ash protein MKLM6_RS03770 1f85b95135909cd707a9151bfc105ca6 154 Gene3D G3DSA:3.30.70.920 66 141 4.9E-10 T 28-03-2018 MKLM6_RS03770 1f85b95135909cd707a9151bfc105ca6 154 Gene3D G3DSA:1.10.10.10 7 65 2.2E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS20755 70e99a836437bf16ab27a9697c62eac7 264 Pfam PF02625 XdhC and CoxI family 13 77 4.3E-13 T 28-03-2018 IPR003777 XdhC- CoxI MKLM6_RS20755 70e99a836437bf16ab27a9697c62eac7 264 Pfam PF13478 XdhC Rossmann domain 109 245 2.7E-29 T 28-03-2018 IPR027051 XdhC Rossmann domain MKLM6_RS20265 4e20058c0c69981cfc819b5bfd765879 357 Pfam PF06996 Type VI secretion, TssG 20 334 1.9E-105 T 28-03-2018 IPR010732 Type VI secretion, TssG-like MKLM6_RS20265 4e20058c0c69981cfc819b5bfd765879 357 TIGRFAM TIGR03347 VI_chp_1: type VI secretion protein, VC_A0111 family 20 334 3.5E-101 T 28-03-2018 IPR010732 Type VI secretion, TssG-like MKLM6_RS02300 cc8b4b0d4f42de1418caf4a3836e227d 1049 Pfam PF10070 Uncharacterized protein conserved in bacteria (DUF2309) 20 989 2.7E-268 T 28-03-2018 IPR018752 Uncharacterised protein family UPF0753 MKLM6_RS02300 cc8b4b0d4f42de1418caf4a3836e227d 1049 Hamap MF_01871 UPF0753 protein . 14 1004 23.102 T 28-03-2018 IPR018752 Uncharacterised protein family UPF0753 MKLM6_RS01075 620496f46afada39c5cf591ae9c31863 385 Pfam PF04230 Polysaccharide pyruvyl transferase 15 310 2.4E-32 T 28-03-2018 IPR007345 Polysaccharide pyruvyl transferase MKLM6_RS11730 cb7ba772e13d6bd0ad8ca4f56f8bc422 122 Gene3D G3DSA:1.10.287.910 21 73 8.9E-17 T 28-03-2018 MKLM6_RS11730 cb7ba772e13d6bd0ad8ca4f56f8bc422 122 Pfam PF02411 MerT mercuric transport protein 17 120 1.5E-30 T 28-03-2018 IPR003457 Mercuric transport protein MerT GO:0015097|GO:0015694|GO:0016020 MKLM6_RS03105 6c004a0952d41d95efb021195a7f15f1 164 Pfam PF02464 Competence-damaged protein 8 160 4.6E-58 T 28-03-2018 IPR008136 CinA, C-terminal MKLM6_RS03105 6c004a0952d41d95efb021195a7f15f1 164 Gene3D G3DSA:3.90.950.20 5 164 5.1E-58 T 28-03-2018 MKLM6_RS03105 6c004a0952d41d95efb021195a7f15f1 164 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 14 158 1.7E-49 T 28-03-2018 IPR008136 CinA, C-terminal MKLM6_RS03105 6c004a0952d41d95efb021195a7f15f1 164 SUPERFAMILY SSF142433 8 161 1.96E-55 T 28-03-2018 IPR008136 CinA, C-terminal MKLM6_RS22580 7ba1fa40372414141e521dfa7f2b76b9 93 Pfam PF07178 TraL protein 5 91 1.1E-21 T 28-03-2018 IPR009838 Type IV conjugative transfer system, protein TraL GO:0000746|GO:0019867 MKLM6_RS22580 7ba1fa40372414141e521dfa7f2b76b9 93 TIGRFAM TIGR02762 TraL_TIGR: type IV conjugative transfer system protein TraL 5 91 6.1E-13 T 28-03-2018 IPR009838 Type IV conjugative transfer system, protein TraL GO:0000746|GO:0019867 MKLM6_RS09650 1d968bd61c2249b04df0e3c8178fe961 105 Pfam PF16785 Small metal-binding protein 10 104 7.1E-20 T 28-03-2018 IPR031877 Metal-binding protein SmbP GO:0046872 MKLM6_RS05910 773bd6412c4e2bf60eaef0841cf54cbd 75 Gene3D G3DSA:1.10.1220.10 1 54 7.9E-6 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 MKLM6_RS22305 1a38f6b1ef3dbea7e44fa3ab6b42588a 385 Pfam PF06250 Protein of unknown function (DUF1016) 16 371 2.8E-93 T 28-03-2018 IPR009362 Protein of unknown function DUF1016 MKLM6_RS03285 24fd010614245ce3c44cc65c8b92dd3d 98 Pfam PF07798 Protein of unknown function (DUF1640) 6 72 9.3E-12 T 28-03-2018 IPR024461 Coiled-coil domain-containing protein 90-like MKLM6_RS19510 5b38d57920eb09fd6819803df296a4cd 416 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 28 204 3.4E-54 T 28-03-2018 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 MKLM6_RS19510 5b38d57920eb09fd6819803df296a4cd 416 Pfam PF01435 Peptidase family M48 208 411 4.3E-41 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MKLM6_RS19510 5b38d57920eb09fd6819803df296a4cd 416 Gene3D G3DSA:3.30.2010.10 203 285 1.0E-22 T 28-03-2018 MKLM6_RS20660 fb2a8e14dbd23aaba6011f51ef47245a 399 Pfam PF12704 MacB-like periplasmic core domain 21 242 2.1E-31 T 28-03-2018 IPR025857 MacB-like periplasmic core domain MKLM6_RS20660 fb2a8e14dbd23aaba6011f51ef47245a 399 Pfam PF02687 FtsX-like permease family 305 392 3.1E-10 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MKLM6_RS09125 eb3288a2cf19df6c43d2953ed75c460f 493 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 14 465 5.5E-127 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 MKLM6_RS09125 eb3288a2cf19df6c43d2953ed75c460f 493 Pfam PF02321 Outer membrane efflux protein 279 463 1.5E-26 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS09125 eb3288a2cf19df6c43d2953ed75c460f 493 Pfam PF02321 Outer membrane efflux protein 72 255 6.6E-18 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS09125 eb3288a2cf19df6c43d2953ed75c460f 493 SUPERFAMILY SSF56954 4 468 2.09E-100 T 28-03-2018 MKLM6_RS09125 eb3288a2cf19df6c43d2953ed75c460f 493 Gene3D G3DSA:1.20.1600.10 21 471 6.2E-98 T 28-03-2018 MKLM6_RS15285 d58716bd898d930365a025ec15bcb291 120 PIRSF PIRSF005610 1 114 6.3E-14 T 28-03-2018 IPR007360 Invasion gene expression up-regulator, SirB MKLM6_RS15285 d58716bd898d930365a025ec15bcb291 120 Pfam PF04247 Invasion gene expression up-regulator, SirB 2 116 2.2E-27 T 28-03-2018 IPR007360 Invasion gene expression up-regulator, SirB MKLM6_RS19755 f61dac45650a9ddd34450fa9640e7803 450 Pfam PF05598 Transposase domain (DUF772) 52 121 1.3E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS19755 f61dac45650a9ddd34450fa9640e7803 450 Pfam PF01609 Transposase DDE domain 274 441 3.7E-21 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS19755 f61dac45650a9ddd34450fa9640e7803 450 Gene3D G3DSA:3.90.350.10 270 407 2.1E-6 T 28-03-2018 IPR014736 Transposase, Tn5-like, core MKLM6_RS16665 dee7ea133b886da8e447ccc0f2f59a50 498 Gene3D G3DSA:3.50.50.60 7 495 6.9E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS16665 dee7ea133b886da8e447ccc0f2f59a50 498 Pfam PF01593 Flavin containing amine oxidoreductase 17 487 8.4E-23 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MKLM6_RS16665 dee7ea133b886da8e447ccc0f2f59a50 498 SUPERFAMILY SSF51905 456 496 6.78E-67 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS16665 dee7ea133b886da8e447ccc0f2f59a50 498 SUPERFAMILY SSF51905 8 322 6.78E-67 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS16665 dee7ea133b886da8e447ccc0f2f59a50 498 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 10 496 3.7E-121 T 28-03-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 MKLM6_RS19760 e0532266c1d06cb8f3387bb2c7acadf0 190 Pfam PF10504 Protein of unknown function (DUF2452) 53 106 9.8E-9 T 28-03-2018 IPR019534 Protein of unknown function DUF2452 MKLM6_RS08735 9d85956da8fef941926e07fe227ffb2a 320 PIRSF PIRSF003097 21 316 4.7E-66 T 28-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 MKLM6_RS12325 5397a5fe1314ab3b4a1bb15ee317fb73 177 Gene3D G3DSA:3.30.530.20 18 177 2.4E-24 T 28-03-2018 IPR023393 START-like domain MKLM6_RS12325 5397a5fe1314ab3b4a1bb15ee317fb73 177 SUPERFAMILY SSF55961 25 176 5.21E-21 T 28-03-2018 MKLM6_RS12325 5397a5fe1314ab3b4a1bb15ee317fb73 177 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 27 174 2.1E-16 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase MKLM6_RS17730 bfb107e1f59f3247c5ccc625dee8fdfe 84 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 46 9.8E-8 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MKLM6_RS17730 bfb107e1f59f3247c5ccc625dee8fdfe 84 Gene3D G3DSA:2.10.260.10 1 83 5.4E-10 T 28-03-2018 MKLM6_RS17730 bfb107e1f59f3247c5ccc625dee8fdfe 84 SUPERFAMILY SSF89447 5 67 3.14E-11 T 28-03-2018 MKLM6_RS13120 4bc7957e3ef71b6d520db057ec40927c 475 Gene3D G3DSA:1.20.210.10 7 460 2.7E-56 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS13120 4bc7957e3ef71b6d520db057ec40927c 475 SUPERFAMILY SSF81442 9 459 1.03E-64 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS13120 4bc7957e3ef71b6d520db057ec40927c 475 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 12 444 1.4E-67 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MKLM6_RS08065 64237e44c5f87c1a1aca1f1d8b32733c 171 Gene3D G3DSA:3.40.50.300 18 147 6.0E-12 T 28-03-2018 MKLM6_RS08065 64237e44c5f87c1a1aca1f1d8b32733c 171 Gene3D G3DSA:3.40.50.300 2 17 8.1E-4 T 28-03-2018 MKLM6_RS08065 64237e44c5f87c1a1aca1f1d8b32733c 171 SUPERFAMILY SSF52540 4 160 3.17E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS08065 64237e44c5f87c1a1aca1f1d8b32733c 171 Pfam PF06414 Zeta toxin 4 143 1.3E-7 T 28-03-2018 IPR010488 Zeta toxin domain GO:0005524|GO:0016301 MKLM6_RS21440 6f923cc635bc0e06aa4008d70a205f56 173 Pfam PF14317 YcxB-like protein 106 163 9.2E-10 T 28-03-2018 IPR025588 YcxB-like protein MKLM6_RS05465 d1ca818d85f0dcce7ccff46dde085876 288 Pfam PF13145 PPIC-type PPIASE domain 135 251 1.4E-8 T 28-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 MKLM6_RS00530 ec1152d218c9b618217f6cc79f002a9d 387 Pfam PF10442 FIST C domain 222 363 1.5E-16 T 28-03-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 MKLM6_RS00530 ec1152d218c9b618217f6cc79f002a9d 387 SMART SM00897 29 221 6.2E-6 T 28-03-2018 IPR013702 FIST domain, N-terminal MKLM6_RS00530 ec1152d218c9b618217f6cc79f002a9d 387 Pfam PF08495 FIST N domain 45 220 8.9E-21 T 28-03-2018 IPR013702 FIST domain, N-terminal MKLM6_RS00530 ec1152d218c9b618217f6cc79f002a9d 387 SMART SM01204 222 365 1.6E-13 T 28-03-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 MKLM6_RS14040 729fdd031db40a0b02756696cf6f83de 98 Pfam PF11342 Protein of unknown function (DUF3144) 8 85 6.2E-32 T 28-03-2018 IPR021490 Protein of unknown function DUF3144 MKLM6_RS22385 d7390f12f4d4901fbabb30b8a69cfd2d 695 Pfam PF07514 Putative helicase 37 339 5.4E-79 T 28-03-2018 IPR011119 Uncharacterised domain, helicase/relaxase, putative MKLM6_RS22385 d7390f12f4d4901fbabb30b8a69cfd2d 695 Gene3D G3DSA:1.10.3210.10 67 287 1.5E-5 T 28-03-2018 MKLM6_RS19650 8d506fe8e886c99fc076230d1c354ca0 179 Gene3D G3DSA:3.40.50.10600 8 156 4.9E-26 T 28-03-2018 MKLM6_RS19650 8d506fe8e886c99fc076230d1c354ca0 179 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 24 114 3.5E-10 T 28-03-2018 IPR000014 PAS domain MKLM6_RS19650 8d506fe8e886c99fc076230d1c354ca0 179 Pfam PF08447 PAS fold 31 114 1.7E-13 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 MKLM6_RS19650 8d506fe8e886c99fc076230d1c354ca0 179 SUPERFAMILY SSF55785 20 117 1.55E-25 T 28-03-2018 IPR000014 PAS domain MKLM6_RS14925 dff0bf9ca5d61e21f093ab9b505111da 513 Pfam PF07693 KAP family P-loop domain 32 336 2.6E-27 T 28-03-2018 IPR011646 KAP family P-loop domain MKLM6_RS14925 dff0bf9ca5d61e21f093ab9b505111da 513 SUPERFAMILY SSF52540 29 105 1.24E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS14925 dff0bf9ca5d61e21f093ab9b505111da 513 SUPERFAMILY SSF52540 241 368 1.24E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS14925 dff0bf9ca5d61e21f093ab9b505111da 513 Gene3D G3DSA:3.40.50.300 8 294 5.9E-10 T 28-03-2018 MKLM6_RS17055 f2b3680f6d3c846485737baa13138527 174 Gene3D G3DSA:3.10.450.40 27 86 2.0E-5 T 28-03-2018 MKLM6_RS17055 f2b3680f6d3c846485737baa13138527 174 Gene3D G3DSA:3.10.450.40 101 162 1.1E-14 T 28-03-2018 MKLM6_RS17055 f2b3680f6d3c846485737baa13138527 174 Pfam PF03413 Peptidase propeptide and YPEB domain 100 159 9.1E-13 T 28-03-2018 IPR025711 PepSY domain MKLM6_RS17055 f2b3680f6d3c846485737baa13138527 174 Pfam PF03413 Peptidase propeptide and YPEB domain 29 83 1.0E-6 T 28-03-2018 IPR025711 PepSY domain MKLM6_RS09380 161adb3c38b21e8253dbc132f001a2c2 273 Gene3D G3DSA:2.40.33.20 2 272 6.0E-50 T 28-03-2018 MKLM6_RS09380 161adb3c38b21e8253dbc132f001a2c2 273 SUPERFAMILY SSF50800 150 262 9.0E-12 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain MKLM6_RS09380 161adb3c38b21e8253dbc132f001a2c2 273 SUPERFAMILY SSF50800 4 44 9.0E-12 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain MKLM6_RS09380 161adb3c38b21e8253dbc132f001a2c2 273 Pfam PF03476 MOSC N-terminal beta barrel domain 3 115 2.1E-29 T 28-03-2018 IPR005303 MOSC, N-terminal beta barrel MKLM6_RS09380 161adb3c38b21e8253dbc132f001a2c2 273 SUPERFAMILY SSF141673 4 130 3.4E-38 T 28-03-2018 MKLM6_RS09380 161adb3c38b21e8253dbc132f001a2c2 273 Pfam PF03473 MOSC domain 142 261 2.2E-30 T 28-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 MKLM6_RS05080 f40e069ca8c57f0fe4dcad27749b4765 370 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 3 337 1.5E-62 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MKLM6_RS05080 f40e069ca8c57f0fe4dcad27749b4765 370 Gene3D G3DSA:3.20.20.70 1 363 1.4E-112 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MKLM6_RS05080 f40e069ca8c57f0fe4dcad27749b4765 370 SUPERFAMILY SSF51395 1 356 3.05E-111 T 28-03-2018 MKLM6_RS10990 3ead940ab57623e14268afcb026cd8aa 266 Pfam PF07277 SapC 15 231 2.2E-72 T 28-03-2018 IPR010836 SapC MKLM6_RS05550 b0120eb0026dc14cafc8e52f0d40cbdd 318 Pfam PF07335 Fungal chitosanase of glycosyl hydrolase group 75 177 300 3.6E-7 T 28-03-2018 IPR009939 Fungal chitosanase KEGG: 00520+3.2.1.132 MKLM6_RS07970 a05f3ccfb492b5c8e67e05e1136d3cea 362 Pfam PF13478 XdhC Rossmann domain 195 336 1.5E-30 T 28-03-2018 IPR027051 XdhC Rossmann domain MKLM6_RS07970 a05f3ccfb492b5c8e67e05e1136d3cea 362 Gene3D G3DSA:3.40.50.20 186 311 2.5E-4 T 28-03-2018 MKLM6_RS07970 a05f3ccfb492b5c8e67e05e1136d3cea 362 Pfam PF02625 XdhC and CoxI family 16 80 1.2E-17 T 28-03-2018 IPR003777 XdhC- CoxI MKLM6_RS01310 5babfd86bee0b724c791214c600b8116 257 Gene3D G3DSA:3.20.20.220 1 251 1.8E-25 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like MKLM6_RS01310 5babfd86bee0b724c791214c600b8116 257 Pfam PF02219 Methylenetetrahydrofolate reductase 78 201 4.0E-8 T 28-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 MKLM6_RS01310 5babfd86bee0b724c791214c600b8116 257 SUPERFAMILY SSF51730 2 233 2.35E-33 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like MKLM6_RS19985 882187101527f6943afbe4bb501fd531 734 Gene3D G3DSA:2.60.40.10 561 713 0.012 T 28-03-2018 IPR013783 Immunoglobulin-like fold MKLM6_RS19985 882187101527f6943afbe4bb501fd531 734 Gene3D G3DSA:2.60.500.10 186 302 4.4E-10 T 28-03-2018 MKLM6_RS09385 1105b884b99607c510d0434568a0e5f1 129 Gene3D G3DSA:2.40.10.220 17 125 5.6E-14 T 28-03-2018 MKLM6_RS09385 1105b884b99607c510d0434568a0e5f1 129 SUPERFAMILY SSF141371 45 124 4.12E-9 T 28-03-2018 MKLM6_RS09385 1105b884b99607c510d0434568a0e5f1 129 Pfam PF07238 PilZ domain 24 119 9.2E-11 T 28-03-2018 IPR009875 PilZ domain GO:0035438 MKLM6_RS14180 b2cc84214e8a9771d20a63463e1b98f6 164 Gene3D G3DSA:3.40.50.1820 1 164 6.0E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS14180 b2cc84214e8a9771d20a63463e1b98f6 164 SUPERFAMILY SSF53474 2 163 5.9E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS03885 93626f96fd2eff47c8adc9404f9b1399 225 Pfam PF01618 MotA/TolQ/ExbB proton channel family 79 208 4.1E-42 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 MKLM6_RS03885 93626f96fd2eff47c8adc9404f9b1399 225 TIGRFAM TIGR02796 tolQ: protein TolQ 6 220 4.7E-87 T 28-03-2018 IPR014163 Tol-Pal system, TolQ GO:0015031|GO:0016021 MKLM6_RS08105 67c1bddfdc5ebe50168e61a310b94977 365 Pfam PF01609 Transposase DDE domain 199 346 1.5E-13 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS08105 67c1bddfdc5ebe50168e61a310b94977 365 Pfam PF05598 Transposase domain (DUF772) 53 128 2.5E-21 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS05415 fd276c210c25efe6396c74cfc7711343 215 Pfam PF13417 Glutathione S-transferase, N-terminal domain 11 81 3.2E-12 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MKLM6_RS05415 fd276c210c25efe6396c74cfc7711343 215 Gene3D G3DSA:3.40.30.10 3 99 6.3E-23 T 28-03-2018 MKLM6_RS05415 fd276c210c25efe6396c74cfc7711343 215 SUPERFAMILY SSF52833 5 86 3.08E-20 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS05415 fd276c210c25efe6396c74cfc7711343 215 SUPERFAMILY SSF47616 85 203 2.63E-13 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like MKLM6_RS05415 fd276c210c25efe6396c74cfc7711343 215 Gene3D G3DSA:1.20.1050.10 100 193 9.7E-17 T 28-03-2018 MKLM6_RS10175 756b0bbbca6a6bae7ac7828b5b17e3c1 179 Gene3D G3DSA:1.10.287.500 13 118 8.2E-9 T 28-03-2018 MKLM6_RS19975 ef276549a3976c3ce37657fdf938d2e7 890 Gene3D G3DSA:3.40.50.920 708 890 9.8E-40 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MKLM6_RS19975 ef276549a3976c3ce37657fdf938d2e7 890 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 10 889 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 MKLM6_RS19975 ef276549a3976c3ce37657fdf938d2e7 890 SUPERFAMILY SSF52518 61 468 5.47E-136 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS19975 ef276549a3976c3ce37657fdf938d2e7 890 Gene3D G3DSA:3.40.50.970 473 707 9.5E-65 T 28-03-2018 MKLM6_RS19975 ef276549a3976c3ce37657fdf938d2e7 890 SUPERFAMILY SSF52518 474 702 1.46E-95 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold MKLM6_RS19975 ef276549a3976c3ce37657fdf938d2e7 890 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 89 301 8.0E-9 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MKLM6_RS19975 ef276549a3976c3ce37657fdf938d2e7 890 PIRSF PIRSF000156 1 890 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 MKLM6_RS19975 ef276549a3976c3ce37657fdf938d2e7 890 SUPERFAMILY SSF52922 705 889 3.11E-57 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MKLM6_RS19975 ef276549a3976c3ce37657fdf938d2e7 890 Gene3D G3DSA:3.40.50.970 60 472 1.9E-85 T 28-03-2018 MKLM6_RS07185 7d1d63c3bdf64c0f558d27cd83104091 125 Pfam PF16137 Domain of unknown function (DUF4845) 32 116 1.0E-22 T 28-03-2018 IPR032314 Protein of unknown function DUF4845 MKLM6_RS11860 169e109c3c98b6ac2c92a36fda31bfe4 166 Pfam PF04536 TPM domain 27 142 2.2E-14 T 28-03-2018 IPR007621 TPM domain MKLM6_RS10410 c2f8390adaa2f24115ff5842315ea5a9 219 Gene3D G3DSA:1.20.5.50 33 155 9.1E-4 T 28-03-2018 MKLM6_RS07290 54b4457bc36ae24a0e5ba02a3f0c63b1 141 Pfam PF03653 Uncharacterised protein family (UPF0093) 2 141 3.3E-51 T 28-03-2018 IPR005265 Uncharacterised protein family UPF0093 MKLM6_RS07290 54b4457bc36ae24a0e5ba02a3f0c63b1 141 PIRSF PIRSF004638 1 141 2.2E-55 T 28-03-2018 IPR005265 Uncharacterised protein family UPF0093 MKLM6_RS07290 54b4457bc36ae24a0e5ba02a3f0c63b1 141 TIGRFAM TIGR00701 TIGR00701: TIGR00701 family protein 2 141 1.0E-44 T 28-03-2018 IPR005265 Uncharacterised protein family UPF0093 MKLM6_RS18605 003943c8b9f1c0b47b728156f348a26a 493 SUPERFAMILY SSF56935 308 491 2.66E-9 T 28-03-2018 MKLM6_RS18605 003943c8b9f1c0b47b728156f348a26a 493 SUPERFAMILY SSF56935 150 237 2.66E-9 T 28-03-2018 MKLM6_RS18605 003943c8b9f1c0b47b728156f348a26a 493 Gene3D G3DSA:2.40.160.10 90 493 1.3E-56 T 28-03-2018 MKLM6_RS18605 003943c8b9f1c0b47b728156f348a26a 493 Pfam PF07396 Phosphate-selective porin O and P 142 493 2.9E-41 T 28-03-2018 IPR010870 Phosphate-selective porin O/P MKLM6_RS00215 dee02e3cce6fdfe615d2253d15bdeb90 471 Pfam PF13148 Protein of unknown function (DUF3987) 174 380 7.5E-8 T 28-03-2018 IPR025048 Protein of unknown function DUF3987) MKLM6_RS00215 dee02e3cce6fdfe615d2253d15bdeb90 471 Gene3D G3DSA:1.10.357.10 308 445 0.0045 T 28-03-2018 MKLM6_RS16505 c5dddd00f3c595153e04e8d4ecc21a92 299 SUPERFAMILY SSF51730 29 282 1.84E-17 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like MKLM6_RS16505 c5dddd00f3c595153e04e8d4ecc21a92 299 Gene3D G3DSA:3.20.20.220 2 284 3.7E-17 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like MKLM6_RS22195 ae04d432e6bfaca7944987ea181451d7 209 Pfam PF09436 Domain of unknown function (DUF2016) 11 76 2.5E-7 T 28-03-2018 IPR018560 Domain of unknown function DUF2016 MKLM6_RS22195 ae04d432e6bfaca7944987ea181451d7 209 TIGRFAM TIGR03735 PRTRC_A: PRTRC system protein A 12 201 2.1E-40 T 28-03-2018 IPR022499 ParB-related, ThiF-related cassette, protein A MKLM6_RS22195 ae04d432e6bfaca7944987ea181451d7 209 Pfam PF14464 Prokaryotic homologs of the JAB domain 89 177 2.7E-9 T 28-03-2018 IPR028090 JAB domain, prokaryotic MKLM6_RS20780 be6adf714a26c3f19db0994dde1ffff1 190 Gene3D G3DSA:3.40.80.10 1 187 5.0E-54 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MKLM6_RS20780 be6adf714a26c3f19db0994dde1ffff1 190 SUPERFAMILY SSF55846 3 180 3.4E-67 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MKLM6_RS20780 be6adf714a26c3f19db0994dde1ffff1 190 SMART SM00644 16 167 6.1E-51 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MKLM6_RS20780 be6adf714a26c3f19db0994dde1ffff1 190 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 27 168 1.0E-27 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MKLM6_RS05125 cfee0b03e8635e24f5a4dc5c99d4c9bb 583 Gene3D G3DSA:3.40.720.10 211 494 3.9E-38 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MKLM6_RS05125 cfee0b03e8635e24f5a4dc5c99d4c9bb 583 SUPERFAMILY SSF53649 217 519 2.06E-40 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MKLM6_RS05125 cfee0b03e8635e24f5a4dc5c99d4c9bb 583 Pfam PF00884 Sulfatase 219 488 6.5E-29 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 MKLM6_RS00490 907e51f085a8b98ca9428bd07c2859b6 158 PIRSF PIRSF003174 4 158 7.2E-62 T 28-03-2018 IPR010292 Uncharacterised protein family CreA MKLM6_RS00490 907e51f085a8b98ca9428bd07c2859b6 158 Pfam PF05981 CreA protein 29 156 4.0E-51 T 28-03-2018 IPR010292 Uncharacterised protein family CreA MKLM6_RS16515 97c0fb543b2d34915fb2c3eaa0c3ba89 373 Gene3D G3DSA:3.40.630.30 137 344 7.2E-18 T 28-03-2018 MKLM6_RS16515 97c0fb543b2d34915fb2c3eaa0c3ba89 373 SUPERFAMILY SSF55729 176 338 1.29E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS16515 97c0fb543b2d34915fb2c3eaa0c3ba89 373 Pfam PF13480 Acetyltransferase (GNAT) domain 183 322 1.4E-24 T 28-03-2018 MKLM6_RS09120 b6b25baa3dd060b69df3278f99996a0c 528 Pfam PF01926 50S ribosome-binding GTPase 58 189 1.2E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS09120 b6b25baa3dd060b69df3278f99996a0c 528 SUPERFAMILY SSF52540 48 270 8.79E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS09120 b6b25baa3dd060b69df3278f99996a0c 528 Gene3D G3DSA:3.40.50.300 24 516 1.7E-21 T 28-03-2018 MKLM6_RS12730 c36b6ca138980b0862aaf83c467b8610 204 Pfam PF01618 MotA/TolQ/ExbB proton channel family 68 187 1.5E-31 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 MKLM6_RS12485 3f8fcbf0b3332ce0b938e8a25d4175ee 213 Gene3D G3DSA:3.40.50.1000 66 209 5.6E-30 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS12485 3f8fcbf0b3332ce0b938e8a25d4175ee 213 Pfam PF13419 Haloacid dehalogenase-like hydrolase 1 177 1.3E-24 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS12485 3f8fcbf0b3332ce0b938e8a25d4175ee 213 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 70 177 3.9E-14 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MKLM6_RS12485 3f8fcbf0b3332ce0b938e8a25d4175ee 213 Gene3D G3DSA:1.10.150.240 7 64 5.9E-9 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 MKLM6_RS12485 3f8fcbf0b3332ce0b938e8a25d4175ee 213 SUPERFAMILY SSF56784 1 205 1.08E-42 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS22220 1f428b4e250ce9e447ac008c7e3843a8 589 Pfam PF07282 Putative transposase DNA-binding domain 483 546 3.4E-7 T 28-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal MKLM6_RS20170 87ea31e3dfb137879626094717b555d6 330 Gene3D G3DSA:3.80.30.20 76 308 7.8E-4 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe MKLM6_RS04215 17ea23a25ad16e2fb029252b50c8c936 243 SUPERFAMILY SSF52540 30 211 6.43E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS04215 17ea23a25ad16e2fb029252b50c8c936 243 Gene3D G3DSA:3.40.50.300 7 164 2.1E-12 T 28-03-2018 MKLM6_RS04215 17ea23a25ad16e2fb029252b50c8c936 243 Pfam PF13401 AAA domain 29 139 3.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS01800 14722f244a5d44f13ff0b4b4abca8f66 566 Gene3D G3DSA:3.20.20.80 50 311 2.1E-35 T 28-03-2018 MKLM6_RS01800 14722f244a5d44f13ff0b4b4abca8f66 566 SUPERFAMILY SSF51445 39 308 5.95E-52 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily MKLM6_RS01800 14722f244a5d44f13ff0b4b4abca8f66 566 Pfam PF00332 Glycosyl hydrolases family 17 231 308 1.1E-7 T 28-03-2018 IPR000490 Glycoside hydrolase family 17 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.39 MKLM6_RS13275 b9bea4541c3283a80971a68718d57a42 189 SUPERFAMILY SSF51197 5 186 3.85E-51 T 28-03-2018 MKLM6_RS13275 b9bea4541c3283a80971a68718d57a42 189 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 7 184 5.2E-25 T 28-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like MKLM6_RS13275 b9bea4541c3283a80971a68718d57a42 189 Gene3D G3DSA:2.60.120.590 1 188 1.0E-43 T 28-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like MKLM6_RS13895 d65d4e8c9e739a7bb771748cf9e9a372 167 Pfam PF12118 SprA-related family 43 158 3.3E-37 T 28-03-2018 IPR021973 SprA-related family MKLM6_RS05920 3d6ad255c215b6d875a1b8ef107ae0af 555 Gene3D G3DSA:1.25.40.10 28 321 6.4E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS05920 3d6ad255c215b6d875a1b8ef107ae0af 555 SMART SM00671 114 149 3.9E-4 T 28-03-2018 IPR006597 Sel1-like repeat MKLM6_RS05920 3d6ad255c215b6d875a1b8ef107ae0af 555 SMART SM00671 34 67 79.0 T 28-03-2018 IPR006597 Sel1-like repeat MKLM6_RS05920 3d6ad255c215b6d875a1b8ef107ae0af 555 SUPERFAMILY SSF81901 36 149 2.62E-9 T 28-03-2018 MKLM6_RS05920 3d6ad255c215b6d875a1b8ef107ae0af 555 SUPERFAMILY SSF81901 211 244 2.62E-9 T 28-03-2018 MKLM6_RS05920 3d6ad255c215b6d875a1b8ef107ae0af 555 SUPERFAMILY SSF47384 265 309 9.61E-5 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MKLM6_RS17630 6c2f5a5d152a70f2176263b5dbc13f0a 63 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 51 6.6E-13 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain MKLM6_RS15175 ed86fd4a1639224b712e9bce7ac5d1d7 209 SUPERFAMILY SSF101262 4 209 2.48E-58 T 28-03-2018 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 MKLM6_RS15175 ed86fd4a1639224b712e9bce7ac5d1d7 209 Pfam PF04961 Formiminotransferase-cyclodeaminase 8 187 5.2E-62 T 28-03-2018 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 MKLM6_RS08175 702cb2cf45573bd4e82626289b86153f 148 SUPERFAMILY SSF52821 31 123 1.22E-12 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS08175 702cb2cf45573bd4e82626289b86153f 148 Gene3D G3DSA:3.40.250.10 19 145 2.6E-9 T 28-03-2018 IPR001763 Rhodanese-like domain MKLM6_RS06640 7618118df0890e2ba186fdbc4446fa1a 224 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 4 220 1.5E-37 T 28-03-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 MKLM6_RS06640 7618118df0890e2ba186fdbc4446fa1a 224 TIGRFAM TIGR01868 casD_Cas5e: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI 4 221 4.1E-47 T 28-03-2018 IPR010147 CRISPR-associated protein, CasD GO:0003723|GO:0051607 MKLM6_RS06640 7618118df0890e2ba186fdbc4446fa1a 224 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 5 46 1.5E-9 T 28-03-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal MKLM6_RS12965 398a0d44d05b3b10c3cf4b65fa729b1f 274 Pfam PF08867 FRG domain 30 118 1.7E-23 T 28-03-2018 IPR014966 FRG domain MKLM6_RS12965 398a0d44d05b3b10c3cf4b65fa729b1f 274 SMART SM00901 27 123 6.3E-37 T 28-03-2018 IPR014966 FRG domain MKLM6_RS04165 b443b49261b0ef0e649d8d41a95666f7 108 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 16 74 7.1E-17 T 28-03-2018 IPR022789 Antitoxin ParD MKLM6_RS04165 b443b49261b0ef0e649d8d41a95666f7 108 SUPERFAMILY SSF47598 14 57 4.67E-9 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 MKLM6_RS04165 b443b49261b0ef0e649d8d41a95666f7 108 Gene3D G3DSA:1.10.1220.10 15 56 5.1E-8 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 MKLM6_RS04165 b443b49261b0ef0e649d8d41a95666f7 108 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 18 70 1.6E-7 T 28-03-2018 IPR022789 Antitoxin ParD MKLM6_RS08425 bbfb7732fa17692b71956d397944941a 256 Pfam PF01618 MotA/TolQ/ExbB proton channel family 96 195 1.2E-36 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 MKLM6_RS13140 88ee39b9e3e4cd47374a916edbfecfa0 408 Pfam PF00872 Transposase, Mutator family 20 384 5.7E-120 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS13140 88ee39b9e3e4cd47374a916edbfecfa0 408 ProSitePatterns PS01007 Transposases, Mutator family, signature. 239 263 - T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS01505 88ee39b9e3e4cd47374a916edbfecfa0 408 Pfam PF00872 Transposase, Mutator family 20 384 5.7E-120 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS01505 88ee39b9e3e4cd47374a916edbfecfa0 408 ProSitePatterns PS01007 Transposases, Mutator family, signature. 239 263 - T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS22710 f5071af61500b040afd71b50bd0d9fc9 87 SUPERFAMILY SSF143081 2 78 1.31E-19 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) MKLM6_RS22710 f5071af61500b040afd71b50bd0d9fc9 87 Pfam PF02586 SOS response associated peptidase (SRAP) 1 78 4.6E-16 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) MKLM6_RS22710 f5071af61500b040afd71b50bd0d9fc9 87 Gene3D G3DSA:3.90.1680.10 1 85 3.4E-19 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) MKLM6_RS21560 2a30434e943c34977a389f8ed0cfd397 674 Gene3D G3DSA:2.40.170.20 185 674 1.0E-54 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS21560 2a30434e943c34977a389f8ed0cfd397 674 Gene3D G3DSA:2.170.130.10 68 184 5.0E-28 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS21560 2a30434e943c34977a389f8ed0cfd397 674 Pfam PF00593 TonB dependent receptor 211 672 2.9E-39 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS21560 2a30434e943c34977a389f8ed0cfd397 674 Pfam PF07715 TonB-dependent Receptor Plug Domain 71 180 4.9E-21 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MKLM6_RS21560 2a30434e943c34977a389f8ed0cfd397 674 SUPERFAMILY SSF56935 65 674 6.59E-97 T 28-03-2018 MKLM6_RS05355 5d98927bb928ebe12991e69a83720eb9 232 Gene3D G3DSA:2.20.20.30 158 185 0.3 T 28-03-2018 MKLM6_RS05355 5d98927bb928ebe12991e69a83720eb9 232 Gene3D G3DSA:2.20.20.30 186 213 0.002 T 28-03-2018 MKLM6_RS05355 5d98927bb928ebe12991e69a83720eb9 232 Pfam PF12773 Double zinc ribbon 165 210 4.7E-9 T 28-03-2018 IPR025874 Double zinc ribbon MKLM6_RS13920 aa9ae795a2317ee6db91ce40ea59489c 157 Pfam PF04170 NlpE N-terminal domain 49 135 5.5E-25 T 28-03-2018 IPR007298 Copper resistance lipoprotein NlpE MKLM6_RS06695 9c330f26b726365b31c2d42b4311adaf 224 PIRSF PIRSF009467 3 224 1.5E-67 T 28-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 MKLM6_RS06695 9c330f26b726365b31c2d42b4311adaf 224 Pfam PF01730 UreF 38 181 7.1E-43 T 28-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 MKLM6_RS06695 9c330f26b726365b31c2d42b4311adaf 224 Hamap MF_01385 Urease accessory protein UreF [ureF]. 6 224 33.531 T 28-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 MKLM6_RS17830 a85fa6dc3395a71febdac3a44da8f7ca 250 Pfam PF02470 MlaD protein 28 87 2.8E-7 T 28-03-2018 IPR003399 Mce/MlaD MKLM6_RS17830 a85fa6dc3395a71febdac3a44da8f7ca 250 Gene3D G3DSA:1.20.120.20 72 250 6.3E-6 T 28-03-2018 MKLM6_RS18900 6b69fe63aaa33588ead2672fd2bf2f9e 90 Pfam PF14026 Protein of unknown function (DUF4242) 4 80 1.6E-30 T 28-03-2018 IPR025336 Protein of unknown function DUF4242 MKLM6_RS11130 ceecc61ab5b7838147d501009acd7956 175 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 8 142 2.9E-47 T 28-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 MKLM6_RS11130 ceecc61ab5b7838147d501009acd7956 175 SUPERFAMILY SSF52540 6 168 5.05E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS11130 ceecc61ab5b7838147d501009acd7956 175 Gene3D G3DSA:3.40.50.300 4 174 1.2E-26 T 28-03-2018 MKLM6_RS11130 ceecc61ab5b7838147d501009acd7956 175 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 8 167 4.9E-42 T 28-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 MKLM6_RS11020 4767793be5da79c150d2e5dc44c081d7 439 Gene3D G3DSA:2.40.160.10 3 439 5.4E-65 T 28-03-2018 MKLM6_RS11020 4767793be5da79c150d2e5dc44c081d7 439 Pfam PF13372 Alginate export 83 386 1.4E-8 T 28-03-2018 IPR025388 Alginate export domain MKLM6_RS11455 a9eef90f9646e4c030eecd8eded20ccf 185 Pfam PF13689 Domain of unknown function (DUF4154) 41 179 1.7E-32 T 28-03-2018 IPR025293 Protein of unknown function DUF4154 MKLM6_RS15910 67d6d8a88112fba45f5238aeb09b5e99 153 Pfam PF07007 Lysozyme inhibitor LprI 65 141 6.1E-10 T 28-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal MKLM6_RS14315 53fb9a77a27c0344bae81848f35f2713 256 Pfam PF09836 Putative DNA-binding domain 6 96 9.4E-22 T 28-03-2018 IPR018640 Putative DNA-binding domain, bacteria MKLM6_RS21990 a234dfd34a1ebd6572198fe0a050ee3b 191 SUPERFAMILY SSF52980 6 163 1.5E-18 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MKLM6_RS21990 a234dfd34a1ebd6572198fe0a050ee3b 191 Gene3D G3DSA:3.90.1570.10 1 181 1.2E-33 T 28-03-2018 MKLM6_RS21990 a234dfd34a1ebd6572198fe0a050ee3b 191 Pfam PF05685 Putative restriction endonuclease 14 152 6.9E-23 T 28-03-2018 IPR008538 Domain of unknown function DUF820 MKLM6_RS04595 63f3958837856d8aabe8b21577259304 158 Pfam PF04319 NifZ domain 9 79 1.4E-30 T 28-03-2018 IPR007415 Nitrogenase MoFe maturation protein, NifZ GO:0009399 MKLM6_RS09115 e6d07084e62663afb5be16883d1a67de 580 Gene3D G3DSA:3.40.50.300 4 476 6.9E-20 T 28-03-2018 MKLM6_RS09115 e6d07084e62663afb5be16883d1a67de 580 Pfam PF01926 50S ribosome-binding GTPase 58 211 9.0E-9 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 MKLM6_RS09115 e6d07084e62663afb5be16883d1a67de 580 SUPERFAMILY SSF52540 47 217 9.82E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS09340 0536fd43ec067a95606666569ca657b0 250 Gene3D G3DSA:3.40.50.150 7 221 1.9E-11 T 28-03-2018 MKLM6_RS09340 0536fd43ec067a95606666569ca657b0 250 SUPERFAMILY SSF53335 28 169 1.23E-11 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS15745 7e7a3d355f6706ab4f7289b56a9cac57 466 Pfam PF05159 Capsule polysaccharide biosynthesis protein 270 400 2.6E-7 T 28-03-2018 IPR007833 Capsule polysaccharide biosynthesis GO:0000271|GO:0015774 MKLM6_RS20250 756714db2a71910ace22e4f541b7ab82 233 Pfam PF01764 Lipase (class 3) 98 130 2.1E-4 T 28-03-2018 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 MKLM6_RS20250 756714db2a71910ace22e4f541b7ab82 233 SUPERFAMILY SSF53474 7 203 1.28E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS20250 756714db2a71910ace22e4f541b7ab82 233 Gene3D G3DSA:3.40.50.1820 1 185 1.1E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS09640 8f696962e939c10e42d1c4766c75f4f3 162 Pfam PF05239 PRC-barrel domain 53 125 3.0E-13 T 28-03-2018 IPR027275 PRC-barrel domain MKLM6_RS09640 8f696962e939c10e42d1c4766c75f4f3 162 SUPERFAMILY SSF50346 50 145 4.12E-19 T 28-03-2018 IPR011033 PRC-barrel-like MKLM6_RS09640 8f696962e939c10e42d1c4766c75f4f3 162 Gene3D G3DSA:3.90.50.10 27 162 2.5E-34 T 28-03-2018 MKLM6_RS00605 a68409a188c57b872fd57dba01095367 283 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 28 204 1.3E-59 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 MKLM6_RS00605 a68409a188c57b872fd57dba01095367 283 SMART SM00470 31 121 4.3E-35 T 28-03-2018 IPR003115 ParB/Sulfiredoxin MKLM6_RS00605 a68409a188c57b872fd57dba01095367 283 Gene3D G3DSA:3.90.1530.10 19 121 9.1E-36 T 28-03-2018 MKLM6_RS00605 a68409a188c57b872fd57dba01095367 283 SUPERFAMILY SSF110849 31 166 3.14E-35 T 28-03-2018 IPR003115 ParB/Sulfiredoxin MKLM6_RS00605 a68409a188c57b872fd57dba01095367 283 Pfam PF02195 ParB-like nuclease domain 32 121 4.2E-29 T 28-03-2018 IPR003115 ParB/Sulfiredoxin MKLM6_RS00605 a68409a188c57b872fd57dba01095367 283 Gene3D G3DSA:1.10.10.730 122 169 1.5E-18 T 28-03-2018 MKLM6_RS08585 dfe2537366651cc18f2106f13bc9e5da 394 Gene3D G3DSA:2.120.10.80 46 141 2.3E-5 T 28-03-2018 IPR015915 Kelch-type beta propeller GO:0005515 MKLM6_RS08585 dfe2537366651cc18f2106f13bc9e5da 394 Gene3D G3DSA:2.120.10.80 142 360 3.0E-12 T 28-03-2018 IPR015915 Kelch-type beta propeller GO:0005515 MKLM6_RS08585 dfe2537366651cc18f2106f13bc9e5da 394 SUPERFAMILY SSF50965 85 156 5.89E-16 T 28-03-2018 IPR011043 Galactose oxidase/kelch, beta-propeller MKLM6_RS08585 dfe2537366651cc18f2106f13bc9e5da 394 SUPERFAMILY SSF50965 197 374 5.89E-16 T 28-03-2018 IPR011043 Galactose oxidase/kelch, beta-propeller MKLM6_RS03620 64164ace2d3324ac415a08f7130203bd 158 SUPERFAMILY SSF54631 1 130 2.4E-31 T 28-03-2018 MKLM6_RS03620 64164ace2d3324ac415a08f7130203bd 158 Pfam PF00571 CBS domain 71 124 8.8E-11 T 28-03-2018 IPR000644 CBS domain MKLM6_RS03620 64164ace2d3324ac415a08f7130203bd 158 Pfam PF00571 CBS domain 3 56 1.1E-9 T 28-03-2018 IPR000644 CBS domain MKLM6_RS03620 64164ace2d3324ac415a08f7130203bd 158 Gene3D G3DSA:3.10.580.10 1 154 1.6E-29 T 28-03-2018 MKLM6_RS03620 64164ace2d3324ac415a08f7130203bd 158 SMART SM00116 78 126 1.6E-9 T 28-03-2018 IPR000644 CBS domain MKLM6_RS03620 64164ace2d3324ac415a08f7130203bd 158 SMART SM00116 10 60 0.001 T 28-03-2018 IPR000644 CBS domain MKLM6_RS14170 e8d5c8910942c4f8c162693d7f24ae26 305 Pfam PF09572 XamI restriction endonuclease 59 290 4.6E-70 T 28-03-2018 IPR019072 Restriction endonuclease, type II, XamI GO:0003677|GO:0009036|GO:0009307 MKLM6_RS14170 e8d5c8910942c4f8c162693d7f24ae26 305 Gene3D G3DSA:3.40.1350.10 159 304 3.9E-4 T 28-03-2018 MKLM6_RS15300 20cb5b512db776b5cdbb39e02a04e2d2 126 TIGRFAM TIGR04073 exo_TIGR04073: putative exosortase-associated protein, TIGR04073 family 36 107 7.9E-23 T 28-03-2018 IPR023824 Conserved hypothetical protein CHP04073, exosortase-affiliated MKLM6_RS04965 ae200d007abe114c11e4aeda86db2145 157 Pfam PF03270 Protein of unknown function, DUF269 36 156 1.8E-50 T 28-03-2018 IPR004952 Uncharacterised protein family UPF0460 MKLM6_RS04965 ae200d007abe114c11e4aeda86db2145 157 TIGRFAM TIGR02935 TIGR02935: probable nitrogen fixation protein 18 155 1.0E-55 T 28-03-2018 IPR004952 Uncharacterised protein family UPF0460 MKLM6_RS04965 ae200d007abe114c11e4aeda86db2145 157 PIRSF PIRSF005788 2 157 1.0E-62 T 28-03-2018 IPR004952 Uncharacterised protein family UPF0460 MKLM6_RS08760 b3c0e02a020e854692d555590215704c 220 Pfam PF13453 Transcription factor zinc-finger 45 87 2.5E-10 T 28-03-2018 IPR027392 Transcription factor zinc-finger MKLM6_RS08760 b3c0e02a020e854692d555590215704c 220 Pfam PF13453 Transcription factor zinc-finger 119 160 1.6E-5 T 28-03-2018 IPR027392 Transcription factor zinc-finger MKLM6_RS16400 b5ff096e4ead78a86f78fc2a625102f0 107 Gene3D G3DSA:2.60.300.12 2 107 9.4E-35 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MKLM6_RS16400 b5ff096e4ead78a86f78fc2a625102f0 107 SUPERFAMILY SSF89360 1 96 8.5E-28 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MKLM6_RS16400 b5ff096e4ead78a86f78fc2a625102f0 107 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 107 3.1E-34 T 28-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 MKLM6_RS16400 b5ff096e4ead78a86f78fc2a625102f0 107 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 28-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 MKLM6_RS16400 b5ff096e4ead78a86f78fc2a625102f0 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 5.5E-22 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MKLM6_RS01925 9d6a95ae7f76fd696a01f4fc627a0e37 147 PIRSF PIRSF006276 1 146 2.4E-44 T 28-03-2018 IPR006015 Universal stress protein A MKLM6_RS01925 9d6a95ae7f76fd696a01f4fc627a0e37 147 Pfam PF00582 Universal stress protein family 4 143 2.3E-32 T 28-03-2018 IPR006016 UspA GO:0006950 MKLM6_RS01925 9d6a95ae7f76fd696a01f4fc627a0e37 147 SUPERFAMILY SSF52402 4 143 5.36E-35 T 28-03-2018 MKLM6_RS01925 9d6a95ae7f76fd696a01f4fc627a0e37 147 PRINTS PR01438 Universal stress protein signature 4 22 7.3E-16 T 28-03-2018 IPR006015 Universal stress protein A MKLM6_RS01925 9d6a95ae7f76fd696a01f4fc627a0e37 147 PRINTS PR01438 Universal stress protein signature 121 143 7.3E-16 T 28-03-2018 IPR006015 Universal stress protein A MKLM6_RS01925 9d6a95ae7f76fd696a01f4fc627a0e37 147 PRINTS PR01438 Universal stress protein signature 104 116 7.3E-16 T 28-03-2018 IPR006015 Universal stress protein A MKLM6_RS01925 9d6a95ae7f76fd696a01f4fc627a0e37 147 Gene3D G3DSA:3.40.50.620 3 147 1.1E-33 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MKLM6_RS02105 bef37bffd7b13279c9de100885cc9a16 173 SUPERFAMILY SSF53271 19 146 2.49E-30 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like MKLM6_RS02105 bef37bffd7b13279c9de100885cc9a16 173 Gene3D G3DSA:3.40.50.2020 7 158 2.1E-18 T 28-03-2018 MKLM6_RS02105 bef37bffd7b13279c9de100885cc9a16 173 Pfam PF00156 Phosphoribosyl transferase domain 14 135 1.1E-13 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MKLM6_RS12100 95aa3f5ef9adb865fdff8526b9c39b98 251 Pfam PF00430 ATP synthase B/B' CF(0) 8 127 1.9E-7 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MKLM6_RS12100 95aa3f5ef9adb865fdff8526b9c39b98 251 Hamap MF_01398 ATP synthase subunit b [atpF]. 2 140 9.777 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MKLM6_RS01615 398cce8d63e47adc4209a38e4d435fdf 176 Pfam PF06146 Phosphate-starvation-inducible E 92 159 9.2E-19 T 28-03-2018 IPR020948 Phosphate-starvation-induced PsiE-like MKLM6_RS21760 17bda514b8a84a19a450fb70f8ce6ddc 443 Gene3D G3DSA:1.20.5.340 141 292 5.5E-24 T 28-03-2018 MKLM6_RS21760 17bda514b8a84a19a450fb70f8ce6ddc 443 Pfam PF02646 RmuC family 131 427 3.5E-107 T 28-03-2018 IPR003798 DNA recombination RmuC MKLM6_RS21760 17bda514b8a84a19a450fb70f8ce6ddc 443 Gene3D G3DSA:1.20.1480.30 340 429 0.086 T 28-03-2018 MKLM6_RS01870 57e6ad341a3a47696dba05d6e4de96fe 192 SUPERFAMILY SSF49384 41 169 1.97E-7 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 MKLM6_RS01870 57e6ad341a3a47696dba05d6e4de96fe 192 Gene3D G3DSA:2.60.40.680 37 181 2.0E-14 T 28-03-2018 MKLM6_RS12725 66d74d1afe69bfca4efb6ec3d3929db0 144 Pfam PF02472 Biopolymer transport protein ExbD/TolR 8 139 4.2E-24 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 MKLM6_RS19445 770dcbcb90c5b1cc53a1bcfc3bad5aa8 251 Pfam PF07238 PilZ domain 115 239 2.5E-6 T 28-03-2018 IPR009875 PilZ domain GO:0035438 MKLM6_RS19445 770dcbcb90c5b1cc53a1bcfc3bad5aa8 251 Gene3D G3DSA:2.30.110.10 8 115 5.8E-26 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MKLM6_RS19445 770dcbcb90c5b1cc53a1bcfc3bad5aa8 251 Hamap MF_01457 Flagellar brake protein YcgR [ycgR]. 2 250 25.445 T 28-03-2018 IPR023787 Type III secretion system flagellar brake protein YcgR GO:0035438|GO:0071945 MKLM6_RS19445 770dcbcb90c5b1cc53a1bcfc3bad5aa8 251 Gene3D G3DSA:2.40.10.220 116 245 2.3E-12 T 28-03-2018 MKLM6_RS19445 770dcbcb90c5b1cc53a1bcfc3bad5aa8 251 Pfam PF07317 Flagellar regulator YcgR 7 111 2.0E-27 T 28-03-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal MKLM6_RS06670 27e70c8b65c6ac9f086b998b5da9e490 476 PIRSF PIRSF012666 1 476 1.1E-146 T 28-03-2018 IPR016602 Uncharacterised conserved protein UCP012666 MKLM6_RS06670 27e70c8b65c6ac9f086b998b5da9e490 476 SUPERFAMILY SSF55931 42 458 2.75E-51 T 28-03-2018 MKLM6_RS20315 1f6553b739b991da36e3612416855677 440 TIGRFAM TIGR03349 IV_VI_DotU: type IV/VI secretion system protein, DotU family 60 268 1.2E-64 T 28-03-2018 IPR017732 Type IV / VI secretion system, DotU MKLM6_RS20315 1f6553b739b991da36e3612416855677 440 Pfam PF00691 OmpA family 336 433 4.6E-16 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS20315 1f6553b739b991da36e3612416855677 440 Gene3D G3DSA:3.30.1330.60 188 440 6.3E-29 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS20315 1f6553b739b991da36e3612416855677 440 SUPERFAMILY SSF103088 331 439 2.09E-24 T 28-03-2018 IPR006665 OmpA-like domain MKLM6_RS20315 1f6553b739b991da36e3612416855677 440 Pfam PF09850 Type VI secretion system protein DotU 61 262 6.2E-63 T 28-03-2018 IPR017732 Type IV / VI secretion system, DotU MKLM6_RS20635 34f0ab86fd05757bb933144c9c0b963f 135 TIGRFAM TIGR04073 exo_TIGR04073: putative exosortase-associated protein, TIGR04073 family 34 105 1.2E-18 T 28-03-2018 IPR023824 Conserved hypothetical protein CHP04073, exosortase-affiliated MKLM6_RS09760 a505680761faf2aebf99b886be3d7a8f 676 Pfam PF06048 Domain of unknown function (DUF927) 131 407 5.4E-77 T 28-03-2018 IPR009270 Domain of unknown function DUF927 MKLM6_RS03940 9841f590b41c26053423d3acd867fc52 328 SUPERFAMILY SSF52540 113 294 7.71E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS03940 9841f590b41c26053423d3acd867fc52 328 Gene3D G3DSA:3.30.1370.10 18 103 0.0015 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 MKLM6_RS03940 9841f590b41c26053423d3acd867fc52 328 Gene3D G3DSA:3.40.50.300 112 317 1.4E-28 T 28-03-2018 MKLM6_RS03940 9841f590b41c26053423d3acd867fc52 328 Pfam PF02562 PhoH-like protein 114 317 1.8E-93 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 MKLM6_RS20850 15bfab8d090e65430ff8bffc08c0ebf3 111 Gene3D G3DSA:2.30.130.30 11 108 2.5E-12 T 28-03-2018 MKLM6_RS20850 15bfab8d090e65430ff8bffc08c0ebf3 111 SUPERFAMILY SSF88697 14 106 8.45E-7 T 28-03-2018 IPR015947 PUA-like domain MKLM6_RS09795 5abdea236086942d949ac4cdb700c069 408 ProSitePatterns PS01007 Transposases, Mutator family, signature. 239 263 - T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS09795 5abdea236086942d949ac4cdb700c069 408 Pfam PF00872 Transposase, Mutator family 20 384 7.3E-121 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS01430 39081bf7977b1d355ddc5a9de4cabe0c 264 Pfam PF02582 Uncharacterised ACR, YagE family COG1723 51 217 1.1E-43 T 28-03-2018 IPR003734 Domain of unknown function DUF155 MKLM6_RS16850 767f85a2c860b02c7033c9b519d51f42 343 Gene3D G3DSA:3.10.350.10 27 81 5.1E-13 T 28-03-2018 MKLM6_RS16850 767f85a2c860b02c7033c9b519d51f42 343 Pfam PF01476 LysM domain 33 77 5.9E-13 T 28-03-2018 IPR018392 LysM domain MKLM6_RS16850 767f85a2c860b02c7033c9b519d51f42 343 SUPERFAMILY SSF54106 32 78 8.76E-7 T 28-03-2018 IPR018392 LysM domain MKLM6_RS09580 e707fbd4b7747c0895039b9697d36691 133 Gene3D G3DSA:2.60.40.1120 33 132 1.2E-4 T 28-03-2018 MKLM6_RS17930 3060e5e8aee586628f017d18c2d3b40a 89 Pfam PF17090 Uncharacterised protein family 25 87 1.2E-9 T 28-03-2018 IPR031381 Uncharacterised protein YtcA MKLM6_RS12705 5e291f7bb5b60fc8fe3e0edea2992141 127 Pfam PF11399 Protein of unknown function (DUF3192) 31 124 8.1E-9 T 28-03-2018 IPR021534 Protein of unknown function DUF3192 MKLM6_RS12705 5e291f7bb5b60fc8fe3e0edea2992141 127 Gene3D G3DSA:3.30.1450.10 25 126 7.5E-5 T 28-03-2018 MKLM6_RS18895 c781a413ab2c68cdea2636b977e2031c 437 Gene3D G3DSA:2.130.10.10 150 417 4.6E-12 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MKLM6_RS18895 c781a413ab2c68cdea2636b977e2031c 437 Gene3D G3DSA:2.130.10.10 15 149 3.7E-4 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MKLM6_RS18895 c781a413ab2c68cdea2636b977e2031c 437 SUPERFAMILY SSF75011 55 379 2.35E-19 T 28-03-2018 MKLM6_RS18895 c781a413ab2c68cdea2636b977e2031c 437 Pfam PF05694 56kDa selenium binding protein (SBP56) 23 426 2.1E-48 T 28-03-2018 IPR008826 Selenium-binding protein GO:0008430 MKLM6_RS03410 4637d1b5e09cf45f6c76a87c60a2a536 141 Pfam PF02472 Biopolymer transport protein ExbD/TolR 16 138 5.3E-29 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 MKLM6_RS20650 63d16b930608cc9d36a5b84645b240ac 91 Pfam PF10719 Late competence development protein ComFB 6 85 9.4E-19 T 28-03-2018 IPR019657 Late competence development protein ComFB MKLM6_RS20945 75b952f32759a3fa1e7eb7fbd897df49 137 Gene3D G3DSA:3.90.1590.10 1 137 9.1E-37 T 28-03-2018 MKLM6_RS20945 75b952f32759a3fa1e7eb7fbd897df49 137 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 27 117 6.4E-21 T 28-03-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 MKLM6_RS20945 75b952f32759a3fa1e7eb7fbd897df49 137 SUPERFAMILY SSF51316 2 136 6.49E-40 T 28-03-2018 IPR011057 Mss4-like MKLM6_RS10555 4af5060fa7052c22460127219ba357f2 482 ProSitePatterns PS00216 Sugar transport proteins signature 1. 343 360 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MKLM6_RS10555 4af5060fa7052c22460127219ba357f2 482 Pfam PF07690 Major Facilitator Superfamily 12 430 4.3E-37 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MKLM6_RS10555 4af5060fa7052c22460127219ba357f2 482 SUPERFAMILY SSF103473 6 194 7.59E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain MKLM6_RS10555 4af5060fa7052c22460127219ba357f2 482 SUPERFAMILY SSF103473 266 460 7.59E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain MKLM6_RS10555 4af5060fa7052c22460127219ba357f2 482 Gene3D G3DSA:1.20.1250.20 275 468 3.0E-20 T 28-03-2018 MKLM6_RS10555 4af5060fa7052c22460127219ba357f2 482 Gene3D G3DSA:1.20.1250.20 4 199 7.1E-26 T 28-03-2018 MKLM6_RS16510 4d535213922bca595d5b8b5238a1cd2c 338 SUPERFAMILY SSF55729 153 304 7.42E-14 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase MKLM6_RS16510 4d535213922bca595d5b8b5238a1cd2c 338 Pfam PF13480 Acetyltransferase (GNAT) domain 153 297 3.2E-23 T 28-03-2018 MKLM6_RS16510 4d535213922bca595d5b8b5238a1cd2c 338 Gene3D G3DSA:3.40.630.30 110 328 4.7E-19 T 28-03-2018 MKLM6_RS15400 b2d5066b062874cdcdd2e18e9398af35 222 Gene3D G3DSA:3.10.560.10 105 219 3.4E-17 T 28-03-2018 MKLM6_RS15400 b2d5066b062874cdcdd2e18e9398af35 222 Gene3D G3DSA:3.30.1950.10 44 104 6.2E-15 T 28-03-2018 MKLM6_RS15400 b2d5066b062874cdcdd2e18e9398af35 222 Pfam PF02563 Polysaccharide biosynthesis/export protein 35 109 1.2E-21 T 28-03-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 MKLM6_RS14470 9a86d5bf1468c67cb06bad33ffd71fd3 201 Pfam PF07589 PEP-CTERM motif 172 196 1.6E-4 T 28-03-2018 IPR013424 PEP-CTERM protein-sorting domain MKLM6_RS01740 1215fa73fe664a59462f565975e8f85a 306 Pfam PF01145 SPFH domain / Band 7 family 25 194 2.0E-32 T 28-03-2018 IPR001107 Band 7 domain MKLM6_RS01740 1215fa73fe664a59462f565975e8f85a 306 SMART SM00244 21 179 3.5E-56 T 28-03-2018 IPR001107 Band 7 domain MKLM6_RS01740 1215fa73fe664a59462f565975e8f85a 306 PRINTS PR00721 Stomatin signature 76 97 9.6E-31 T 28-03-2018 IPR001972 Stomatin family GO:0016020 MKLM6_RS01740 1215fa73fe664a59462f565975e8f85a 306 PRINTS PR00721 Stomatin signature 111 128 9.6E-31 T 28-03-2018 IPR001972 Stomatin family GO:0016020 MKLM6_RS01740 1215fa73fe664a59462f565975e8f85a 306 PRINTS PR00721 Stomatin signature 155 173 9.6E-31 T 28-03-2018 IPR001972 Stomatin family GO:0016020 MKLM6_RS01740 1215fa73fe664a59462f565975e8f85a 306 PRINTS PR00721 Stomatin signature 131 154 9.6E-31 T 28-03-2018 IPR001972 Stomatin family GO:0016020 MKLM6_RS01740 1215fa73fe664a59462f565975e8f85a 306 PRINTS PR00721 Stomatin signature 174 195 9.6E-31 T 28-03-2018 IPR001972 Stomatin family GO:0016020 MKLM6_RS01740 1215fa73fe664a59462f565975e8f85a 306 ProSitePatterns PS01270 Band 7 protein family signature. 135 163 - T 28-03-2018 IPR018080 Band 7/stomatin-like, conserved site MKLM6_RS01740 1215fa73fe664a59462f565975e8f85a 306 SUPERFAMILY SSF117892 52 186 9.42E-43 T 28-03-2018 IPR001107 Band 7 domain MKLM6_RS10580 a7c00287e74cf0e88461cfe2c3a2dafc 324 Pfam PF02628 Cytochrome oxidase assembly protein 12 308 3.5E-52 T 28-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 MKLM6_RS07220 5c1e8a07e5f62196886ad66c78c122d2 241 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 13 223 1.2E-48 T 28-03-2018 MKLM6_RS09675 db2a81e2b897c5031a216ec2236e41b9 104 Pfam PF04972 BON domain 37 103 2.1E-21 T 28-03-2018 IPR007055 BON domain MKLM6_RS09675 db2a81e2b897c5031a216ec2236e41b9 104 SMART SM00749 42 104 1.4E-4 T 28-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria MKLM6_RS20270 b545a77a808a56324cc6bc599318b315 628 Pfam PF05947 Type VI secretion system, TssF 6 625 2.3E-219 T 28-03-2018 IPR010272 Type VI secretion system, TssF-like MKLM6_RS20270 b545a77a808a56324cc6bc599318b315 628 PIRSF PIRSF028304 1 628 6.8E-185 T 28-03-2018 IPR010272 Type VI secretion system, TssF-like MKLM6_RS20270 b545a77a808a56324cc6bc599318b315 628 TIGRFAM TIGR03359 VI_chp_6: type VI secretion protein, TIGR03359 family 5 626 2.6E-199 T 28-03-2018 IPR010272 Type VI secretion system, TssF-like MKLM6_RS07820 02ee2741384141f67bd9649523e460db 291 Gene3D G3DSA:1.10.10.10 1 53 0.0097 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS07820 02ee2741384141f67bd9649523e460db 291 Gene3D G3DSA:3.40.91.30 188 286 4.5E-11 T 28-03-2018 MKLM6_RS10950 312ef92bb3de768f70828cd303db051d 163 Pfam PF16694 Cytochrome P460 36 158 5.5E-35 T 28-03-2018 IPR032033 Cytochrome P460 MKLM6_RS20665 8482ce4b31543138955bb8a18aedcba3 401 Pfam PF12704 MacB-like periplasmic core domain 22 243 8.1E-30 T 28-03-2018 IPR025857 MacB-like periplasmic core domain MKLM6_RS20665 8482ce4b31543138955bb8a18aedcba3 401 Pfam PF02687 FtsX-like permease family 306 394 8.7E-8 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MKLM6_RS01305 576f524df9f3df15fb8c1d21797d66e3 465 Gene3D G3DSA:3.20.20.20 104 332 1.9E-9 T 28-03-2018 MKLM6_RS01305 576f524df9f3df15fb8c1d21797d66e3 465 SUPERFAMILY SSF51717 120 327 2.75E-27 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MKLM6_RS12525 9df4b2c4f9d392a203e6da69fc8cfc32 259 Gene3D G3DSA:3.40.50.1820 9 254 1.9E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS12525 9df4b2c4f9d392a203e6da69fc8cfc32 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 2.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS12525 9df4b2c4f9d392a203e6da69fc8cfc32 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 81 94 2.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS12525 9df4b2c4f9d392a203e6da69fc8cfc32 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 199 213 2.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS12525 9df4b2c4f9d392a203e6da69fc8cfc32 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 35 50 2.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MKLM6_RS12525 9df4b2c4f9d392a203e6da69fc8cfc32 259 Pfam PF12146 Serine aminopeptidase, S33 35 223 6.4E-12 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 MKLM6_RS12525 9df4b2c4f9d392a203e6da69fc8cfc32 259 SUPERFAMILY SSF53474 10 251 1.52E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS22555 d08a49614344b430654abca1f502c447 156 Pfam PF09676 Type IV conjugative transfer system lipoprotein (TraV) 31 95 1.4E-15 T 28-03-2018 IPR014118 Type IV conjugative transfer system protein TraV MKLM6_RS01285 c0b2864f6f26ea3f157aa3c20969a147 223 PIRSF PIRSF016919 39 220 3.1E-32 T 28-03-2018 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein MKLM6_RS01285 c0b2864f6f26ea3f157aa3c20969a147 223 Pfam PF04955 HupE / UreJ protein 52 212 1.1E-33 T 28-03-2018 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein MKLM6_RS03365 8c20886b7e17a2de83004226943d6d41 271 SMART SM00382 26 220 4.9E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain MKLM6_RS03365 8c20886b7e17a2de83004226943d6d41 271 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MKLM6_RS03365 8c20886b7e17a2de83004226943d6d41 271 Pfam PF00005 ABC transporter 17 171 3.7E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS03365 8c20886b7e17a2de83004226943d6d41 271 SUPERFAMILY SSF52540 6 237 2.44E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS03365 8c20886b7e17a2de83004226943d6d41 271 Gene3D G3DSA:3.40.50.300 1 240 6.6E-54 T 28-03-2018 MKLM6_RS11265 76776f440273ffc79cb7d661cc191f80 272 Pfam PF01061 ABC-2 type transporter 14 196 6.4E-15 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MKLM6_RS06125 470f00df4f79e3670de30e7cbf436b67 209 Gene3D G3DSA:1.20.120.330 1 122 1.2E-4 T 28-03-2018 MKLM6_RS17180 b9359d3cc304f4e70fd51614ce9b6cf1 81 Pfam PF07362 Post-segregation antitoxin CcdA 11 81 1.8E-29 T 28-03-2018 IPR009956 Post-segregation antitoxin CcdA MKLM6_RS20050 a42924a076d086dfefe46d60b2612f0f 125 Gene3D G3DSA:2.60.40.1470 2 125 2.2E-45 T 28-03-2018 IPR007474 ApaG domain MKLM6_RS20050 a42924a076d086dfefe46d60b2612f0f 125 Pfam PF04379 ApaG domain 18 102 1.5E-35 T 28-03-2018 IPR007474 ApaG domain MKLM6_RS20050 a42924a076d086dfefe46d60b2612f0f 125 Hamap MF_00791 Protein ApaG [apaG]. 1 125 33.678 T 28-03-2018 IPR023065 Uncharacterised protein family ApaG MKLM6_RS20050 a42924a076d086dfefe46d60b2612f0f 125 SUPERFAMILY SSF110069 5 125 5.76E-49 T 28-03-2018 IPR007474 ApaG domain MKLM6_RS22680 a30b94326bb4d5c0f56f80f82bbd5d6e 192 Pfam PF06736 Protein of unknown function (DUF1211) 5 89 1.1E-29 T 28-03-2018 IPR010617 Endosomal/lysomomal potassium channel TMEM175 GO:0005267 MKLM6_RS05060 7005c62ba44c027b6a9386e6893a390a 291 Hamap MF_00188 Protease HtpX [htpX]. 1 290 25.039 T 28-03-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 MKLM6_RS05060 7005c62ba44c027b6a9386e6893a390a 291 Pfam PF01435 Peptidase family M48 81 289 2.1E-39 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MKLM6_RS05060 7005c62ba44c027b6a9386e6893a390a 291 Gene3D G3DSA:3.30.2010.10 72 165 6.3E-21 T 28-03-2018 MKLM6_RS02150 41e4dc42050f7da991f26d845930d91e 598 Pfam PF13519 von Willebrand factor type A domain 96 203 9.6E-15 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS02150 41e4dc42050f7da991f26d845930d91e 598 Gene3D G3DSA:1.25.40.10 346 465 1.6E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS02150 41e4dc42050f7da991f26d845930d91e 598 SUPERFAMILY SSF53300 94 280 2.07E-19 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS02150 41e4dc42050f7da991f26d845930d91e 598 Pfam PF00515 Tetratricopeptide repeat 405 438 3.0E-9 T 28-03-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 MKLM6_RS02150 41e4dc42050f7da991f26d845930d91e 598 Gene3D G3DSA:3.40.50.410 87 295 1.1E-24 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS02150 41e4dc42050f7da991f26d845930d91e 598 SMART SM00028 405 438 2.5E-8 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MKLM6_RS02150 41e4dc42050f7da991f26d845930d91e 598 SMART SM00327 93 259 3.2E-7 T 28-03-2018 IPR002035 von Willebrand factor, type A MKLM6_RS02150 41e4dc42050f7da991f26d845930d91e 598 SUPERFAMILY SSF48452 358 456 1.82E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS13315 e178201985d37229223f00e2c00ec340 242 SUPERFAMILY SSF56300 2 107 2.78E-27 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS13315 e178201985d37229223f00e2c00ec340 242 SUPERFAMILY SSF56300 142 233 2.78E-27 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS13315 e178201985d37229223f00e2c00ec340 242 Gene3D G3DSA:3.60.21.10 1 239 2.1E-25 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like MKLM6_RS13315 e178201985d37229223f00e2c00ec340 242 Pfam PF00149 Calcineurin-like phosphoesterase 16 207 3.6E-10 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MKLM6_RS02765 f1d2cea5c5550834fec3e4b01703a6c9 128 Pfam PF00072 Response regulator receiver domain 7 120 7.9E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS02765 f1d2cea5c5550834fec3e4b01703a6c9 128 SUPERFAMILY SSF52172 3 125 2.7E-36 T 28-03-2018 IPR011006 CheY-like superfamily MKLM6_RS02765 f1d2cea5c5550834fec3e4b01703a6c9 128 Gene3D G3DSA:3.40.50.2300 2 127 4.7E-36 T 28-03-2018 MKLM6_RS02765 f1d2cea5c5550834fec3e4b01703a6c9 128 SMART SM00448 5 119 2.5E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MKLM6_RS04235 81a4058bceb88b5063e5a72fce865854 94 SUPERFAMILY SSF46689 14 94 1.11E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 MKLM6_RS17440 59dc6f80a7e9e93318c18c26019fc549 150 Gene3D G3DSA:2.60.120.10 1 149 1.3E-7 T 28-03-2018 IPR014710 RmlC-like jelly roll fold MKLM6_RS17440 59dc6f80a7e9e93318c18c26019fc549 150 SUPERFAMILY SSF51182 6 139 5.78E-7 T 28-03-2018 IPR011051 RmlC-like cupin domain MKLM6_RS07335 1603cb7f519d6d64747268066afa96df 219 Pfam PF01169 Uncharacterized protein family UPF0016 25 98 2.7E-20 T 28-03-2018 IPR001727 Gdt1 family MKLM6_RS07335 1603cb7f519d6d64747268066afa96df 219 Pfam PF01169 Uncharacterized protein family UPF0016 125 197 2.7E-19 T 28-03-2018 IPR001727 Gdt1 family MKLM6_RS03475 f6748cbdb22a60e101c1f3b82071ae66 201 Pfam PF13689 Domain of unknown function (DUF4154) 45 188 3.8E-36 T 28-03-2018 IPR025293 Protein of unknown function DUF4154 MKLM6_RS06850 aa2b5cca4ecf069de91684179c22b510 344 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 343 144.487 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 MKLM6_RS06850 aa2b5cca4ecf069de91684179c22b510 344 PIRSF PIRSF002465 4 342 2.8E-124 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 MKLM6_RS06850 aa2b5cca4ecf069de91684179c22b510 344 Gene3D G3DSA:3.40.718.10 2 339 1.0E-105 T 28-03-2018 MKLM6_RS06850 aa2b5cca4ecf069de91684179c22b510 344 Pfam PF02504 Fatty acid synthesis protein 6 328 1.3E-102 T 28-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 MKLM6_RS06850 aa2b5cca4ecf069de91684179c22b510 344 SUPERFAMILY SSF53659 6 337 2.06E-101 T 28-03-2018 MKLM6_RS06850 aa2b5cca4ecf069de91684179c22b510 344 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 7 336 1.7E-107 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 MKLM6_RS17195 94360991a1ec431cfa703be9da0ab275 406 Pfam PF05816 Toxic anion resistance protein (TelA) 60 382 7.4E-91 T 28-03-2018 IPR008863 Toxic anion resistance MKLM6_RS00440 94b4740818c225a95ccae0e09c579d16 416 SUPERFAMILY SSF118215 5 410 8.63E-97 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS00440 94b4740818c225a95ccae0e09c579d16 416 Pfam PF00375 Sodium:dicarboxylate symporter family 6 409 4.8E-107 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS00440 94b4740818c225a95ccae0e09c579d16 416 PRINTS PR00173 Glutamate-aspartate symporter signature 303 329 1.7E-37 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS00440 94b4740818c225a95ccae0e09c579d16 416 PRINTS PR00173 Glutamate-aspartate symporter signature 338 357 1.7E-37 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS00440 94b4740818c225a95ccae0e09c579d16 416 PRINTS PR00173 Glutamate-aspartate symporter signature 201 220 1.7E-37 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS00440 94b4740818c225a95ccae0e09c579d16 416 PRINTS PR00173 Glutamate-aspartate symporter signature 5 25 1.7E-37 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS00440 94b4740818c225a95ccae0e09c579d16 416 PRINTS PR00173 Glutamate-aspartate symporter signature 48 68 1.7E-37 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS00440 94b4740818c225a95ccae0e09c579d16 416 PRINTS PR00173 Glutamate-aspartate symporter signature 78 103 1.7E-37 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS00440 94b4740818c225a95ccae0e09c579d16 416 PRINTS PR00173 Glutamate-aspartate symporter signature 153 175 1.7E-37 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS00440 94b4740818c225a95ccae0e09c579d16 416 PRINTS PR00173 Glutamate-aspartate symporter signature 365 385 1.7E-37 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS00440 94b4740818c225a95ccae0e09c579d16 416 Gene3D G3DSA:1.10.3860.10 1 414 4.0E-104 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MKLM6_RS16020 fd10641db9c70141c6f4713cae91ee2d 107 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 2 103 2.6E-19 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 MKLM6_RS16020 fd10641db9c70141c6f4713cae91ee2d 107 SUPERFAMILY SSF50118 1 106 7.68E-25 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor MKLM6_RS16020 fd10641db9c70141c6f4713cae91ee2d 107 Gene3D G3DSA:2.30.30.110 1 107 2.8E-17 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor MKLM6_RS00030 567af5343ad78169b26be2773e7bbfb1 374 Pfam PF12698 ABC-2 family transporter protein 24 363 4.1E-32 T 28-03-2018 MKLM6_RS00030 567af5343ad78169b26be2773e7bbfb1 374 Gene3D G3DSA:3.40.1710.10 40 191 5.7E-22 T 28-03-2018 MKLM6_RS09015 48a31b824fdb603e87906d6b9181981b 138 Pfam PF03994 Domain of Unknown Function (DUF350) 84 136 5.7E-6 T 28-03-2018 IPR007140 Protein of unknown function DUF350 MKLM6_RS09015 48a31b824fdb603e87906d6b9181981b 138 Pfam PF03994 Domain of Unknown Function (DUF350) 21 72 5.7E-8 T 28-03-2018 IPR007140 Protein of unknown function DUF350 MKLM6_RS19870 bad20cadf861c02042c7e9a36a34d3cd 65 Pfam PF10771 Winged helix-turn-helix domain (DUF2582) 4 60 2.5E-20 T 28-03-2018 IPR019707 Winged helix-turn-helix domain (DUF2582) MKLM6_RS19870 bad20cadf861c02042c7e9a36a34d3cd 65 Gene3D G3DSA:1.10.10.10 2 63 2.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS04080 3f8bac0c5c8780ba573b74f765064e64 859 Pfam PF12094 Protein of unknown function (DUF3570) 2 493 1.9E-139 T 28-03-2018 IPR021953 Protein of unknown function DUF3570 MKLM6_RS07805 17ee7ea8ffe9aa14ab654cdd669c8e38 198 Gene3D G3DSA:3.90.1570.10 2 186 6.1E-40 T 28-03-2018 MKLM6_RS07805 17ee7ea8ffe9aa14ab654cdd669c8e38 198 Pfam PF05685 Putative restriction endonuclease 13 175 3.3E-32 T 28-03-2018 IPR008538 Domain of unknown function DUF820 MKLM6_RS07805 17ee7ea8ffe9aa14ab654cdd669c8e38 198 SUPERFAMILY SSF52980 5 181 1.72E-23 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MKLM6_RS20715 5ba999c2a49e30e2d553d218226a2d64 585 Gene3D G3DSA:3.50.50.60 2 579 9.6E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS20715 5ba999c2a49e30e2d553d218226a2d64 585 Pfam PF00732 GMC oxidoreductase 211 310 3.8E-8 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MKLM6_RS20715 5ba999c2a49e30e2d553d218226a2d64 585 SUPERFAMILY SSF51905 514 577 8.52E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS20715 5ba999c2a49e30e2d553d218226a2d64 585 SUPERFAMILY SSF51905 211 319 8.52E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS20715 5ba999c2a49e30e2d553d218226a2d64 585 SUPERFAMILY SSF51905 5 184 8.52E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MKLM6_RS20715 5ba999c2a49e30e2d553d218226a2d64 585 Pfam PF05199 GMC oxidoreductase 508 568 6.5E-13 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 MKLM6_RS17190 6f5b4b7ef16a26441ccc45a627e1a67c 350 Pfam PF04024 PspC domain 11 67 5.4E-14 T 28-03-2018 IPR007168 Phage shock protein, PspC, N-terminal MKLM6_RS18855 58f0bb345e00794244ef6bdcb0a1b2f7 616 SUPERFAMILY SSF56519 56 249 2.75E-53 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MKLM6_RS18855 58f0bb345e00794244ef6bdcb0a1b2f7 616 Gene3D G3DSA:3.40.710.10 246 614 1.6E-95 T 28-03-2018 MKLM6_RS18855 58f0bb345e00794244ef6bdcb0a1b2f7 616 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 20 609 3.9E-236 T 28-03-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0016020 MKLM6_RS18855 58f0bb345e00794244ef6bdcb0a1b2f7 616 Pfam PF00905 Penicillin binding protein transpeptidase domain 267 605 4.6E-78 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MKLM6_RS18855 58f0bb345e00794244ef6bdcb0a1b2f7 616 Pfam PF03717 Penicillin-binding Protein dimerisation domain 64 234 3.9E-45 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MKLM6_RS18855 58f0bb345e00794244ef6bdcb0a1b2f7 616 SUPERFAMILY SSF56601 250 611 3.82E-105 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MKLM6_RS18855 58f0bb345e00794244ef6bdcb0a1b2f7 616 Gene3D G3DSA:3.90.1310.10 34 245 7.0E-54 T 28-03-2018 MKLM6_RS04285 a7bc34c31bd3d2058b2327460e41ee2b 421 Pfam PF08808 RES domain 209 374 5.1E-18 T 28-03-2018 IPR014914 RES domain MKLM6_RS04285 a7bc34c31bd3d2058b2327460e41ee2b 421 SMART SM00953 223 382 4.3E-5 T 28-03-2018 IPR014914 RES domain MKLM6_RS04925 f55ac04f8d5a220d2f71395aec778e07 66 Pfam PF11127 Protein of unknown function (DUF2892) 2 56 1.2E-15 T 28-03-2018 IPR021309 Protein of unknown function DUF2892 MKLM6_RS16750 6a04a6e51b7367a315efed4d105313ee 101 Pfam PF11390 NADH-dependant formate dehydrogenase delta subunit FdsD 40 94 2.1E-14 T 28-03-2018 IPR021074 Formate dehydrogenase, delta subunit MKLM6_RS15085 4f07047bf9a53f6a07f3598ad37ac210 238 Pfam PF08241 Methyltransferase domain 75 123 8.7E-8 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MKLM6_RS15085 4f07047bf9a53f6a07f3598ad37ac210 238 Gene3D G3DSA:3.40.50.150 64 208 1.6E-13 T 28-03-2018 MKLM6_RS15085 4f07047bf9a53f6a07f3598ad37ac210 238 SUPERFAMILY SSF53335 76 181 2.73E-14 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS20570 ee59a0b433b57485db5d723998c5befd 156 Pfam PF04138 GtrA-like protein 39 155 1.0E-21 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 MKLM6_RS21900 2022fe64f03cf641ddf2fff637b90214 275 SUPERFAMILY SSF110849 53 121 6.41E-12 T 28-03-2018 IPR003115 ParB/Sulfiredoxin MKLM6_RS21900 2022fe64f03cf641ddf2fff637b90214 275 Gene3D G3DSA:3.90.1530.10 20 121 1.3E-7 T 28-03-2018 MKLM6_RS15170 18ef5bd855b1ab20d7b926b69e78c586 358 Pfam PF01757 Acyltransferase family 19 345 7.9E-27 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 MKLM6_RS05470 42a6221f8f99f0cce6e139cbc015b903 316 Pfam PF13795 HupE / UreJ protein 136 281 4.3E-44 T 28-03-2018 IPR032809 Putative HupE/UreJ protein MKLM6_RS06770 e06463e2ad4bd7f33158012ac72c8bed 269 Gene3D G3DSA:3.40.50.300 17 267 4.5E-53 T 28-03-2018 MKLM6_RS06770 e06463e2ad4bd7f33158012ac72c8bed 269 SUPERFAMILY SSF52540 27 267 5.85E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS06770 e06463e2ad4bd7f33158012ac72c8bed 269 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 247 268 1.6E-7 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal MKLM6_RS06770 e06463e2ad4bd7f33158012ac72c8bed 269 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 28 268 1.2E-117 T 28-03-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD MKLM6_RS06770 e06463e2ad4bd7f33158012ac72c8bed 269 Pfam PF00005 ABC transporter 44 199 3.9E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MKLM6_RS20320 01470bcdebfd33b729e1a901db3ff1ad 446 TIGRFAM TIGR03353 VI_chp_4: type VI secretion protein, VC_A0114 family 5 444 2.3E-154 T 28-03-2018 IPR010263 Type VI secretion protein, VC_A0114 MKLM6_RS20320 01470bcdebfd33b729e1a901db3ff1ad 446 Pfam PF05936 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE 19 443 1.0E-154 T 28-03-2018 IPR010263 Type VI secretion protein, VC_A0114 MKLM6_RS16015 be939bfb47f16bc02734e41a57288bd5 70 Pfam PF11455 Protein of unknown function (DUF3018) 7 69 9.7E-29 T 28-03-2018 IPR021558 Protein of unknown function DUF3018 MKLM6_RS00175 8871a323ae8cde4a464a0ffc8413d239 120 Gene3D G3DSA:1.10.10.10 16 71 2.1E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS17290 1d774f83dc9927383c1ad267e96e2217 85 Gene3D G3DSA:1.10.1200.10 2 84 1.6E-15 T 28-03-2018 MKLM6_RS17290 1d774f83dc9927383c1ad267e96e2217 85 ProSitePatterns PS00012 Phosphopantetheine attachment site. 36 51 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site MKLM6_RS17290 1d774f83dc9927383c1ad267e96e2217 85 SUPERFAMILY SSF47336 2 82 2.09E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS17290 1d774f83dc9927383c1ad267e96e2217 85 Pfam PF00550 Phosphopantetheine attachment site 7 80 7.2E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS21425 7ad686d6c9796c6be51ff306799f40dd 404 SMART SM00052 3 248 6.0E-82 T 28-03-2018 IPR001633 EAL domain MKLM6_RS21425 7ad686d6c9796c6be51ff306799f40dd 404 SUPERFAMILY SSF141868 9 256 3.14E-75 T 28-03-2018 IPR001633 EAL domain MKLM6_RS21425 7ad686d6c9796c6be51ff306799f40dd 404 Gene3D G3DSA:3.20.20.450 5 260 6.9E-77 T 28-03-2018 IPR001633 EAL domain MKLM6_RS21425 7ad686d6c9796c6be51ff306799f40dd 404 Pfam PF13682 Chemoreceptor zinc-binding domain 274 347 8.5E-13 T 28-03-2018 IPR025991 Chemoreceptor zinc-binding domain MKLM6_RS21425 7ad686d6c9796c6be51ff306799f40dd 404 Pfam PF00563 EAL domain 11 243 1.8E-65 T 28-03-2018 IPR001633 EAL domain MKLM6_RS08405 ffd2393f149835602efa5a26e07b3a03 153 Pfam PF01322 Cytochrome C' 26 147 1.7E-27 T 28-03-2018 IPR002321 Cytochrome c, class II GO:0005506|GO:0009055|GO:0020037 MKLM6_RS08405 ffd2393f149835602efa5a26e07b3a03 153 SUPERFAMILY SSF47175 23 147 2.5E-27 T 28-03-2018 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 MKLM6_RS08405 ffd2393f149835602efa5a26e07b3a03 153 Gene3D G3DSA:1.20.120.10 23 150 2.1E-24 T 28-03-2018 MKLM6_RS08405 ffd2393f149835602efa5a26e07b3a03 153 PIRSF PIRSF000027 4 152 5.3E-24 T 28-03-2018 IPR012127 Cytochrome c prime GO:0005506|GO:0009055|GO:0020037|GO:0042597 MKLM6_RS20565 d6a081225ab14fdd9c63050077d78731 154 Pfam PF05258 Protein of unknown function (DUF721) 28 95 1.5E-6 T 28-03-2018 IPR007922 Protein of unknown function DUF721/UPF0232 MKLM6_RS06610 73dbb1dc13552e0d3447e5b23ee14a01 93 Gene3D G3DSA:3.30.2310.20 2 88 1.0E-15 T 28-03-2018 MKLM6_RS06610 73dbb1dc13552e0d3447e5b23ee14a01 93 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 81 2.0E-11 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MKLM6_RS06610 73dbb1dc13552e0d3447e5b23ee14a01 93 SUPERFAMILY SSF143011 1 81 2.49E-14 T 28-03-2018 IPR035095 Toxin RelE-like domain MKLM6_RS18165 1527914c0b6bed1d4297d1c0354a3e5f 160 Gene3D G3DSA:3.30.429.10 1 140 3.2E-38 T 28-03-2018 MKLM6_RS18165 1527914c0b6bed1d4297d1c0354a3e5f 160 SUPERFAMILY SSF55331 2 59 4.35E-7 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily MKLM6_RS18165 1527914c0b6bed1d4297d1c0354a3e5f 160 Pfam PF14832 Putative oxalocrotonate tautomerase enzyme 1 136 8.6E-47 T 28-03-2018 IPR028116 Putative oxalocrotonate tautomerase MKLM6_RS14150 f2da74a5c244f0b32f8ae66ad66c39d0 359 Gene3D G3DSA:3.40.50.1110 18 331 1.9E-53 T 28-03-2018 MKLM6_RS14150 f2da74a5c244f0b32f8ae66ad66c39d0 359 Pfam PF00657 GDSL-like Lipase/Acylhydrolase 29 322 7.8E-10 T 28-03-2018 IPR001087 GDSL lipase/esterase GO:0016788 MKLM6_RS14150 f2da74a5c244f0b32f8ae66ad66c39d0 359 SUPERFAMILY SSF52266 28 44 1.65E-9 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain MKLM6_RS14150 f2da74a5c244f0b32f8ae66ad66c39d0 359 SUPERFAMILY SSF52266 83 326 1.65E-9 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain MKLM6_RS05295 0d79300834e2b2593d90ab13281dc316 288 Pfam PF13730 Helix-turn-helix domain 44 97 1.2E-8 T 28-03-2018 MKLM6_RS05295 0d79300834e2b2593d90ab13281dc316 288 Gene3D G3DSA:1.10.10.10 15 281 4.2E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS01825 586321ab196a00d1e663231fc7ad3b86 272 SUPERFAMILY SSF53167 10 192 1.4E-10 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MKLM6_RS01825 586321ab196a00d1e663231fc7ad3b86 272 Gene3D G3DSA:3.40.50.1580 5 227 6.5E-9 T 28-03-2018 MKLM6_RS21565 4e7f329068fa26f8b0f1c6aa1b6677a2 191 Pfam PF13689 Domain of unknown function (DUF4154) 48 186 1.7E-35 T 28-03-2018 IPR025293 Protein of unknown function DUF4154 MKLM6_RS14255 0e70c1e9547d00454f0a79e08310727c 256 SUPERFAMILY SSF56219 8 253 7.07E-28 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MKLM6_RS14255 0e70c1e9547d00454f0a79e08310727c 256 Gene3D G3DSA:3.60.10.10 2 255 4.9E-28 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MKLM6_RS14255 0e70c1e9547d00454f0a79e08310727c 256 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 13 228 4.3E-12 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MKLM6_RS10690 5ab28869a9ab271df134d484072efa83 363 Pfam PF10994 Protein of unknown function (DUF2817) 13 347 2.3E-84 T 28-03-2018 IPR021259 Protein of unknown function DUF2817 MKLM6_RS10690 5ab28869a9ab271df134d484072efa83 363 Gene3D G3DSA:3.40.630.10 15 294 9.8E-18 T 28-03-2018 MKLM6_RS10690 5ab28869a9ab271df134d484072efa83 363 SUPERFAMILY SSF53187 181 256 2.51E-16 T 28-03-2018 MKLM6_RS10690 5ab28869a9ab271df134d484072efa83 363 SUPERFAMILY SSF53187 55 137 2.51E-16 T 28-03-2018 MKLM6_RS08305 f18097894699369e6cf509418bcd22c8 95 Pfam PF13098 Thioredoxin-like domain 1 78 2.9E-7 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS08305 f18097894699369e6cf509418bcd22c8 95 Gene3D G3DSA:3.40.30.10 1 89 6.0E-9 T 28-03-2018 MKLM6_RS08305 f18097894699369e6cf509418bcd22c8 95 SUPERFAMILY SSF52833 1 81 5.38E-11 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS03100 652e416b9b15c009bbd94d14c4cb8cce 192 Pfam PF04367 Protein of unknown function (DUF502) 60 149 1.9E-23 T 28-03-2018 IPR007462 Protein of unknown function DUF502 MKLM6_RS09845 8fb5ee20e93991baa4d5f7580347b836 183 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 3 158 2.6E-11 T 28-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase MKLM6_RS03415 3f7a9b84acb9d1b2d62b69ad1f37b487 247 Pfam PF01618 MotA/TolQ/ExbB proton channel family 95 210 5.1E-34 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 MKLM6_RS04160 6fa36cd399eb209817e01f17fb10de55 79 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 8 63 9.5E-6 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MKLM6_RS12770 3d37ed7bbe1ca8033ec90cd5cde643ba 126 Gene3D G3DSA:2.40.10.220 2 115 3.4E-9 T 28-03-2018 MKLM6_RS12770 3d37ed7bbe1ca8033ec90cd5cde643ba 126 SUPERFAMILY SSF141371 29 96 3.34E-7 T 28-03-2018 MKLM6_RS12770 3d37ed7bbe1ca8033ec90cd5cde643ba 126 Pfam PF07238 PilZ domain 30 110 4.4E-7 T 28-03-2018 IPR009875 PilZ domain GO:0035438 MKLM6_RS01070 4aa34a3f6e2cbfd0b7f1896745a60bba 188 Gene3D G3DSA:2.160.10.10 12 188 2.9E-32 T 28-03-2018 MKLM6_RS01070 4aa34a3f6e2cbfd0b7f1896745a60bba 188 SUPERFAMILY SSF51161 42 180 8.73E-37 T 28-03-2018 IPR011004 Trimeric LpxA-like MKLM6_RS01070 4aa34a3f6e2cbfd0b7f1896745a60bba 188 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 128 161 1.2E-7 T 28-03-2018 IPR001451 Hexapeptide repeat MKLM6_RS01215 071cc00129eccb23b97cdae9196a6454 1319 Pfam PF02514 CobN/Magnesium Chelatase 133 1171 1.8E-303 T 28-03-2018 IPR003672 CobN/magnesium chelatase GO:0009058 MKLM6_RS15555 ef5b7f1c7e0a7f87b51ded7f8b7ba516 77 TIGRFAM TIGR02574 stabl_TIGR02574: putative addiction module component, TIGR02574 family 8 70 8.6E-20 T 28-03-2018 IPR013406 Conserved hypothetical protein CHP02574, addiction module MKLM6_RS15555 ef5b7f1c7e0a7f87b51ded7f8b7ba516 77 Pfam PF09720 Putative addiction module component 11 65 3.1E-15 T 28-03-2018 IPR013406 Conserved hypothetical protein CHP02574, addiction module MKLM6_RS21350 90824e1cb07abde6eb4ecc5667e23f64 614 Gene3D G3DSA:3.40.50.2300 400 552 6.8E-17 T 28-03-2018 MKLM6_RS21350 90824e1cb07abde6eb4ecc5667e23f64 614 Pfam PF04348 LppC putative lipoprotein 67 605 8.2E-81 T 28-03-2018 IPR007443 Penicillin-binding protein activator LpoA MKLM6_RS21350 90824e1cb07abde6eb4ecc5667e23f64 614 SUPERFAMILY SSF53822 284 605 3.92E-61 T 28-03-2018 IPR028082 Periplasmic binding protein-like I MKLM6_RS21350 90824e1cb07abde6eb4ecc5667e23f64 614 Gene3D G3DSA:3.40.50.2300 283 399 1.5E-20 T 28-03-2018 MKLM6_RS16580 df7339f963484c48ca23b7092d0c2a6a 257 Pfam PF12048 Protein of unknown function (DUF3530) 22 105 2.1E-19 T 28-03-2018 IPR022529 Protein of unknown function DUF3530 MKLM6_RS16580 df7339f963484c48ca23b7092d0c2a6a 257 Pfam PF12048 Protein of unknown function (DUF3530) 122 251 8.5E-13 T 28-03-2018 IPR022529 Protein of unknown function DUF3530 MKLM6_RS16580 df7339f963484c48ca23b7092d0c2a6a 257 SUPERFAMILY SSF53474 49 250 4.93E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS16580 df7339f963484c48ca23b7092d0c2a6a 257 Gene3D G3DSA:3.40.50.1820 40 257 2.0E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS16870 0541a4a87c4ca21f16250c922b619e2e 188 Pfam PF14334 Domain of unknown function (DUF4390) 31 184 1.7E-35 T 28-03-2018 IPR025500 Protein of unknown function DUF4390 MKLM6_RS06615 c9878928f8beb1d8df1ae20eb4263f62 516 TIGRFAM TIGR02547 casA_cse1: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 2 507 1.3E-59 T 28-03-2018 IPR013381 CRISPR-associated protein Cse1 MKLM6_RS06615 c9878928f8beb1d8df1ae20eb4263f62 516 Pfam PF09481 CRISPR-associated protein Cse1 (CRISPR_cse1) 2 474 5.3E-55 T 28-03-2018 IPR013381 CRISPR-associated protein Cse1 MKLM6_RS04665 6aeb20ba9a94512f06b1a18912f8005e 284 Pfam PF13289 SIR2-like domain 111 266 4.3E-6 T 28-03-2018 MKLM6_RS06080 fccab05f95aa84e1ebd02aabcdc7975d 341 SUPERFAMILY SSF103481 39 140 2.62E-15 T 28-03-2018 MKLM6_RS06080 fccab05f95aa84e1ebd02aabcdc7975d 341 Pfam PF00892 EamA-like transporter family 9 136 1.1E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MKLM6_RS17785 c718b658595bd886b9ad824e506473c1 293 Gene3D G3DSA:2.40.50.90 9 199 9.4E-13 T 28-03-2018 IPR035437 Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain MKLM6_RS17785 c718b658595bd886b9ad824e506473c1 293 SUPERFAMILY SSF50199 51 193 4.71E-7 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold MKLM6_RS19070 20648d3711b8f472762eb4baded4a4d8 183 Gene3D G3DSA:3.30.230.60 7 174 1.1E-60 T 28-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 MKLM6_RS19070 20648d3711b8f472762eb4baded4a4d8 183 SUPERFAMILY SSF54211 4 175 9.1E-55 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MKLM6_RS19070 20648d3711b8f472762eb4baded4a4d8 183 Pfam PF08714 Formaldehyde-activating enzyme (Fae) 9 173 3.8E-61 T 28-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 MKLM6_RS19070 20648d3711b8f472762eb4baded4a4d8 183 TIGRFAM TIGR03126 one_C_fae: formaldehyde-activating enzyme 24 172 2.2E-43 T 28-03-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 MKLM6_RS04240 e843cf0ca2841ae825a61d0723ccd57e 231 Gene3D G3DSA:1.20.58.120 5 35 0.45 T 28-03-2018 IPR003103 BAG domain GO:0051087 Reactome: R-HSA-3371453 MKLM6_RS06245 ce46deee1664fb7072139a2a6a308a79 445 Gene3D G3DSA:1.20.1600.10 18 443 1.0E-83 T 28-03-2018 MKLM6_RS06245 ce46deee1664fb7072139a2a6a308a79 445 SUPERFAMILY SSF56954 3 443 1.44E-86 T 28-03-2018 MKLM6_RS06245 ce46deee1664fb7072139a2a6a308a79 445 Pfam PF02321 Outer membrane efflux protein 258 442 1.1E-30 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS06245 ce46deee1664fb7072139a2a6a308a79 445 Pfam PF02321 Outer membrane efflux protein 31 234 2.9E-32 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MKLM6_RS04755 8618ee6f8e7d6aac3b9368ad4edaec73 29 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 8 29 3.1E-6 T 28-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 MKLM6_RS03890 95d3406653df4d7a8d8a959246a0ce76 152 Pfam PF02472 Biopolymer transport protein ExbD/TolR 15 147 2.2E-27 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 MKLM6_RS03890 95d3406653df4d7a8d8a959246a0ce76 152 TIGRFAM TIGR02801 tolR: protein TolR 17 145 1.6E-40 T 28-03-2018 IPR014168 Biopolymer transport, TolR GO:0015031|GO:0016021 MKLM6_RS00925 1c8e8d9662a5563e0548716013fa0693 345 Pfam PF01548 Transposase 18 163 6.7E-22 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 MKLM6_RS00925 1c8e8d9662a5563e0548716013fa0693 345 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 296 5.7E-19 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 MKLM6_RS02385 af4f61389fb890709c77655ca9ed850c 167 Pfam PF01420 Type I restriction modification DNA specificity domain 9 151 5.0E-17 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MKLM6_RS02385 af4f61389fb890709c77655ca9ed850c 167 Gene3D G3DSA:3.90.220.20 2 161 1.1E-26 T 28-03-2018 MKLM6_RS02385 af4f61389fb890709c77655ca9ed850c 167 SUPERFAMILY SSF116734 6 152 7.19E-28 T 28-03-2018 MKLM6_RS09305 f6e4a2fd75e90ec5fee831660f2a56d1 352 SUPERFAMILY SSF53756 11 263 2.9E-7 T 28-03-2018 MKLM6_RS09305 f6e4a2fd75e90ec5fee831660f2a56d1 352 Gene3D G3DSA:3.40.50.2000 36 271 3.7E-6 T 28-03-2018 MKLM6_RS02880 5c2b4f40ab6f1f0f3fded870dfc6ebf9 262 Pfam PF01925 Sulfite exporter TauE/SafE 9 260 1.1E-50 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MKLM6_RS14100 45ca4a2b379724fd5488bc68abc791ba 207 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 78 2.1E-11 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MKLM6_RS14100 45ca4a2b379724fd5488bc68abc791ba 207 Gene3D G3DSA:1.20.1050.10 86 204 7.2E-10 T 28-03-2018 MKLM6_RS14100 45ca4a2b379724fd5488bc68abc791ba 207 Gene3D G3DSA:3.40.30.10 2 85 2.6E-22 T 28-03-2018 MKLM6_RS14100 45ca4a2b379724fd5488bc68abc791ba 207 SUPERFAMILY SSF52833 1 83 4.94E-22 T 28-03-2018 IPR012336 Thioredoxin-like fold MKLM6_RS14100 45ca4a2b379724fd5488bc68abc791ba 207 SUPERFAMILY SSF47616 81 202 2.8E-11 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like MKLM6_RS22160 0102ca1abc82e242ff72877cffce17d0 408 Pfam PF06666 Protein of unknown function (DUF1173) 4 386 1.3E-121 T 28-03-2018 IPR009553 Protein of unknown function DUF1173 MKLM6_RS20445 7505b44e8680180da15c5aea101d9763 150 Pfam PF06073 Bacterial protein of unknown function (DUF934) 50 149 3.1E-31 T 28-03-2018 IPR008318 Uncharacterised conserved protein UCP030820 MKLM6_RS20445 7505b44e8680180da15c5aea101d9763 150 PIRSF PIRSF030820 1 150 1.5E-39 T 28-03-2018 IPR008318 Uncharacterised conserved protein UCP030820 MKLM6_RS18985 ca5c3fef6c31776e6281a46e94578adb 206 Pfam PF07796 Protein of unknown function (DUF1638) 42 192 4.3E-24 T 28-03-2018 IPR012437 Domain of unknown function DUF1638 MKLM6_RS10330 3e28bcf5bbbfc10647f6a177211d2690 132 ProSitePatterns PS00550 Hemerythrin family signature. 54 77 - T 28-03-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 MKLM6_RS10330 3e28bcf5bbbfc10647f6a177211d2690 132 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 5 123 1.0E-23 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 MKLM6_RS10330 3e28bcf5bbbfc10647f6a177211d2690 132 SUPERFAMILY SSF47188 1 122 6.02E-23 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 MKLM6_RS10330 3e28bcf5bbbfc10647f6a177211d2690 132 Gene3D G3DSA:1.20.120.50 1 123 1.3E-24 T 28-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 MKLM6_RS21685 828724b24fdcb62ee47a6874d0da5886 222 Gene3D G3DSA:1.10.10.10 140 217 1.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS21685 828724b24fdcb62ee47a6874d0da5886 222 SUPERFAMILY SSF55811 4 140 4.06E-26 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MKLM6_RS21685 828724b24fdcb62ee47a6874d0da5886 222 Gene3D G3DSA:3.90.79.10 7 139 1.6E-25 T 28-03-2018 MKLM6_RS21685 828724b24fdcb62ee47a6874d0da5886 222 SUPERFAMILY SSF46785 145 213 5.17E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MKLM6_RS21685 828724b24fdcb62ee47a6874d0da5886 222 Pfam PF00293 NUDIX domain 11 119 6.1E-6 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MKLM6_RS20520 9c1d3e0931f8409e352701f8ba0a635f 389 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 19 375 6.0E-121 T 28-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 MKLM6_RS20520 9c1d3e0931f8409e352701f8ba0a635f 389 Pfam PF01098 Cell cycle protein 21 376 6.1E-98 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 MKLM6_RS20520 9c1d3e0931f8409e352701f8ba0a635f 389 Hamap MF_00913 Putative lipid II flippase FtsW [ftsW]. 16 385 39.356 T 28-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 MKLM6_RS19075 74a4da8e43f745acd3df69753f7937d5 44 TIGRFAM TIGR02106 cyd_oper_ybgT: cyd operon protein YbgT 1 26 7.2E-17 T 28-03-2018 IPR011724 Cyd operon protein YbgT MetaCyc: PWY-7545 MKLM6_RS19075 74a4da8e43f745acd3df69753f7937d5 44 Pfam PF08173 Membrane bound YbgT-like protein 1 26 1.7E-15 T 28-03-2018 IPR012994 Membrane bound YbgT-like MKLM6_RS20970 f8d94287dc82cdbbe267cd2919d66bb3 324 Pfam PF16220 Domain of unknown function (DUF4880) 14 56 8.3E-13 T 28-03-2018 IPR032623 FecR, N-terminal MKLM6_RS20970 f8d94287dc82cdbbe267cd2919d66bb3 324 PIRSF PIRSF018266 3 324 5.4E-84 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component MKLM6_RS20970 f8d94287dc82cdbbe267cd2919d66bb3 324 Pfam PF04773 FecR protein 115 207 5.7E-21 T 28-03-2018 IPR006860 FecR protein MKLM6_RS19455 0374951347fd7f768ea1ad6ba6df7428 372 Pfam PF07589 PEP-CTERM motif 347 369 7.4E-5 T 28-03-2018 IPR013424 PEP-CTERM protein-sorting domain MKLM6_RS19455 0374951347fd7f768ea1ad6ba6df7428 372 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 348 370 1.8E-4 T 28-03-2018 IPR013424 PEP-CTERM protein-sorting domain MKLM6_RS17350 0e67d5bb9caac99a8199cf9a66c28f03 64 Pfam PF13617 YnbE-like lipoprotein 8 61 4.0E-27 T 28-03-2018 IPR025985 YnbE-like lipoprotein MKLM6_RS17350 0e67d5bb9caac99a8199cf9a66c28f03 64 ProDom PD052969 LIPOPROTEIN PRECURSOR SIGNAL YNBE MEMBRANE OUTER POSSIBLE SIMILAR ECS2004 SO2063 14 64 3.0E-14 T 28-03-2018 MKLM6_RS11495 d9d7c1e3da40e04dbe291ac16d72a8db 201 Pfam PF05275 Copper resistance protein B precursor (CopB) 3 201 1.4E-68 T 28-03-2018 IPR007939 Copper resistance B precursor GO:0005507|GO:0006878|GO:0009279 MKLM6_RS11495 d9d7c1e3da40e04dbe291ac16d72a8db 201 Gene3D G3DSA:2.40.128.130 12 197 4.7E-4 T 28-03-2018 MKLM6_RS00135 a27648720c25bde6efbf51c57032ff52 559 Pfam PF03235 Protein of unknown function DUF262 18 237 3.8E-21 T 28-03-2018 IPR004919 Domain of unknown function DUF262 MKLM6_RS10395 f13b0990417db661664faa8d79f33c5e 134 Pfam PF02472 Biopolymer transport protein ExbD/TolR 11 131 8.2E-29 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 MKLM6_RS08650 ffb4e9c3e5ed55f0de5ca3e062804378 576 SUPERFAMILY SSF52540 52 307 4.57E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MKLM6_RS08650 ffb4e9c3e5ed55f0de5ca3e062804378 576 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 55 201 2.3E-13 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain MKLM6_RS08650 ffb4e9c3e5ed55f0de5ca3e062804378 576 Gene3D G3DSA:3.40.50.300 51 295 8.0E-42 T 28-03-2018 MKLM6_RS16620 3f8fa112d30defa5ab9062c5bc618d56 86 Pfam PF04193 PQ loop repeat 3 56 3.5E-11 T 28-03-2018 IPR006603 PQ-loop repeat MKLM6_RS05630 dfc1efc23629343e5111634ffe94ffe0 61 Gene3D G3DSA:3.40.50.1000 2 61 6.5E-7 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS05630 dfc1efc23629343e5111634ffe94ffe0 61 SUPERFAMILY SSF56784 5 59 1.98E-8 T 28-03-2018 IPR023214 HAD-like domain MKLM6_RS00910 7a51558286939f7bc0b938488e8e61fd 74 Pfam PF01206 Sulfurtransferase TusA 4 72 3.5E-22 T 28-03-2018 IPR001455 TusA-like domain MKLM6_RS00910 7a51558286939f7bc0b938488e8e61fd 74 SUPERFAMILY SSF64307 4 72 3.4E-21 T 28-03-2018 IPR001455 TusA-like domain MKLM6_RS00910 7a51558286939f7bc0b938488e8e61fd 74 Gene3D G3DSA:3.30.110.40 1 74 1.7E-22 T 28-03-2018 IPR001455 TusA-like domain MKLM6_RS07885 03ebe706c10231c892a84d8f38f83d58 109 Pfam PF16785 Small metal-binding protein 4 106 2.5E-31 T 28-03-2018 IPR031877 Metal-binding protein SmbP GO:0046872 MKLM6_RS12230 adddf8522d8143ef174f91207bb7f5e8 364 Pfam PF04250 Protein of unknown function (DUF429) 20 211 1.4E-6 T 28-03-2018 IPR007362 Protein of unknown function DUF429 MKLM6_RS11430 4a734ca0e059ba11628b2e1b87b09047 286 SUPERFAMILY SSF56317 3 276 8.24E-56 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS11430 4a734ca0e059ba11628b2e1b87b09047 286 Pfam PF00795 Carbon-nitrogen hydrolase 3 219 3.9E-26 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS11430 4a734ca0e059ba11628b2e1b87b09047 286 Gene3D G3DSA:3.60.110.10 1 283 1.2E-51 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MKLM6_RS15655 7b72bf4106bd90f412310d25147b8239 96 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 25 93 4.9E-7 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS15655 7b72bf4106bd90f412310d25147b8239 96 Gene3D G3DSA:1.10.760.10 17 95 3.2E-12 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS15655 7b72bf4106bd90f412310d25147b8239 96 SUPERFAMILY SSF46626 9 94 6.65E-14 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MKLM6_RS19395 2acfade39f686787d6185350a93cea77 174 SMART SM00014 60 169 7.9E-16 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MKLM6_RS19395 2acfade39f686787d6185350a93cea77 174 SUPERFAMILY SSF48317 7 171 7.06E-37 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MKLM6_RS19395 2acfade39f686787d6185350a93cea77 174 Gene3D G3DSA:1.20.144.10 10 172 5.1E-27 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MKLM6_RS19395 2acfade39f686787d6185350a93cea77 174 Pfam PF01569 PAP2 superfamily 63 171 3.9E-22 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MKLM6_RS06415 609237b2e81428c6e414c13ddadfb102 165 Pfam PF06841 T4-like virus tail tube protein gp19 40 143 4.8E-17 T 28-03-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 MKLM6_RS08960 7474cf6833340968b66278c76bc3535a 76 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 3 47 1.3E-12 T 28-03-2018 IPR022453 Zinc finger, MqsA-type MKLM6_RS07880 786d5d2067b59db62961e13fb2e45264 372 Pfam PF13795 HupE / UreJ protein 177 334 1.4E-44 T 28-03-2018 IPR032809 Putative HupE/UreJ protein MKLM6_RS07880 786d5d2067b59db62961e13fb2e45264 372 ProSitePatterns PS00018 EF-hand calcium-binding domain. 52 64 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site MKLM6_RS18040 b68c99815ea7628b18b52863a49952d0 238 Gene3D G3DSA:2.60.120.430 25 205 1.3E-4 T 28-03-2018 MKLM6_RS20720 2a7ff28cd5f0aea31458655da2897e0f 580 Gene3D G3DSA:3.40.50.1820 223 578 1.1E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS20720 2a7ff28cd5f0aea31458655da2897e0f 580 SUPERFAMILY SSF53474 230 578 1.83E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS01290 0d9df0a606ece7a619f2b07a0bf40792 274 Pfam PF14717 Domain of unknown function (DUF4465) 72 245 6.2E-51 T 28-03-2018 IPR027828 Protein of unknown function DUF4465 MKLM6_RS14790 e57e4d9b828fc858d205b39240e6763e 74 Pfam PF09720 Putative addiction module component 12 65 1.6E-13 T 28-03-2018 IPR013406 Conserved hypothetical protein CHP02574, addiction module MKLM6_RS14305 c11f2d580a4f4de373eded45ccd7cc95 91 Pfam PF10048 Predicted integral membrane protein (DUF2282) 35 85 6.7E-24 T 28-03-2018 IPR018740 Protein of unknown function DUF2282, integral membrane MKLM6_RS17295 0bb2b6fd7df7cc3e91860573e8dccf97 82 Pfam PF00550 Phosphopantetheine attachment site 10 76 3.6E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS17295 0bb2b6fd7df7cc3e91860573e8dccf97 82 SUPERFAMILY SSF47336 3 80 1.96E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain MKLM6_RS17295 0bb2b6fd7df7cc3e91860573e8dccf97 82 Gene3D G3DSA:1.10.1200.10 1 82 2.3E-16 T 28-03-2018 MKLM6_RS08545 a13ce25ddba97326d113ec7067f7c2ef 129 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 13 123 2.5E-20 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 MKLM6_RS08545 a13ce25ddba97326d113ec7067f7c2ef 129 Gene3D G3DSA:2.30.30.110 9 129 2.2E-22 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor MKLM6_RS08545 a13ce25ddba97326d113ec7067f7c2ef 129 SUPERFAMILY SSF50118 10 126 3.71E-24 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor MKLM6_RS10720 dbc5f98d19540f4f34233a709f580b33 513 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 55 214 4.1E-30 T 28-03-2018 MKLM6_RS02325 1687b6658f20737b54d8d8554c161119 519 Pfam PF00916 Sulfate permease family 12 388 6.5E-56 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MKLM6_RS00255 7b738c1097758e7e8471c35dd3668a91 92 Gene3D G3DSA:3.30.2310.20 1 92 1.4E-24 T 28-03-2018 MKLM6_RS00255 7b738c1097758e7e8471c35dd3668a91 92 Pfam PF05015 RelE-like toxin of type II toxin-antitoxin system HigB 3 92 1.2E-26 T 28-03-2018 IPR007711 Toxin HigB-1 MKLM6_RS00255 7b738c1097758e7e8471c35dd3668a91 92 SUPERFAMILY SSF143011 1 92 1.09E-15 T 28-03-2018 IPR035095 Toxin RelE-like domain MKLM6_RS00050 4c35f0b9e1361ee3e3029a64d85810ca 122 SUPERFAMILY SSF48498 10 117 6.67E-5 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MKLM6_RS00050 4c35f0b9e1361ee3e3029a64d85810ca 122 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 64 116 2.4E-6 T 28-03-2018 MKLM6_RS00050 4c35f0b9e1361ee3e3029a64d85810ca 122 Gene3D G3DSA:1.10.357.10 5 122 2.1E-21 T 28-03-2018 MKLM6_RS00500 59a8cfacf5449272fb9fdef82d2bc027 171 Pfam PF13689 Domain of unknown function (DUF4154) 33 168 1.8E-28 T 28-03-2018 IPR025293 Protein of unknown function DUF4154 MKLM6_RS15740 05193145dd7b15e061178c20093f34cf 300 Gene3D G3DSA:3.40.50.150 61 288 4.5E-24 T 28-03-2018 MKLM6_RS15740 05193145dd7b15e061178c20093f34cf 300 SUPERFAMILY SSF53335 96 286 2.17E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS15740 05193145dd7b15e061178c20093f34cf 300 Pfam PF13489 Methyltransferase domain 93 241 9.8E-14 T 28-03-2018 MKLM6_RS21415 0b5d640d3870d8f9ed067f38b3e43e4a 157 Pfam PF10027 Predicted integral membrane protein (DUF2269) 5 151 4.3E-51 T 28-03-2018 IPR018729 Protein of unknown function DUF2269, transmembrane MKLM6_RS20705 68e248df0d18ba968714bb9f2256d48a 707 Pfam PF01757 Acyltransferase family 15 361 5.6E-22 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 MKLM6_RS20705 68e248df0d18ba968714bb9f2256d48a 707 Gene3D G3DSA:3.40.50.1110 448 702 1.1E-7 T 28-03-2018 MKLM6_RS17160 af2e8a69bac57c279495a34f9ee2a81e 139 Gene3D G3DSA:3.40.50.9200 24 137 0.0024 T 28-03-2018 MKLM6_RS05480 cb40cb4aea59b7ca0e49a8a8ae7aa732 837 Gene3D G3DSA:3.40.50.150 426 701 2.3E-17 T 28-03-2018 MKLM6_RS05480 cb40cb4aea59b7ca0e49a8a8ae7aa732 837 SUPERFAMILY SSF53335 424 623 9.75E-33 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MKLM6_RS05480 cb40cb4aea59b7ca0e49a8a8ae7aa732 837 SUPERFAMILY SSF103473 13 393 3.4E-6 T 28-03-2018 IPR020846 Major facilitator superfamily domain MKLM6_RS12000 729c7b15916ebc661dbf392d8156f5e1 191 Pfam PF13689 Domain of unknown function (DUF4154) 43 186 2.6E-37 T 28-03-2018 IPR025293 Protein of unknown function DUF4154 MKLM6_RS20290 f0c6b7975159f2d1735592ece01e9112 495 TIGRFAM TIGR03355 VI_chp_2: type VI secretion protein, EvpB/VC_A0108 family 21 491 2.0E-218 T 28-03-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath MKLM6_RS20290 f0c6b7975159f2d1735592ece01e9112 495 Pfam PF05943 Type VI secretion protein, EvpB/VC_A0108, tail sheath 67 491 6.2E-192 T 28-03-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath MKLM6_RS02030 c12b50bbd82ed57de2fc79778ead38cb 213 Gene3D G3DSA:3.40.50.1010 1 194 1.1E-4 T 28-03-2018 IPR029060 PIN domain-like MKLM6_RS07270 d421e475532bccef1561a911a13be192 527 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 63 218 9.8E-12 T 28-03-2018 MKLM6_RS14995 692b8e29a7a9f95ab0a3a299f914c617 281 Pfam PF09839 Uncharacterized protein conserved in bacteria (DUF2066) 36 273 9.9E-59 T 28-03-2018 IPR018642 Protein of unknown function DUF2066 MKLM6_RS15995 46b7be631815591d9a4c65c185ffc8de 408 ProSitePatterns PS01007 Transposases, Mutator family, signature. 239 263 - T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS15995 46b7be631815591d9a4c65c185ffc8de 408 Pfam PF00872 Transposase, Mutator family 20 384 9.4E-120 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS16920 f1f9b65f8e42d2e00350a1bbc8475490 246 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 22 183 7.6E-35 T 28-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 MKLM6_RS16920 f1f9b65f8e42d2e00350a1bbc8475490 246 Pfam PF01066 CDP-alcohol phosphatidyltransferase 16 79 3.8E-12 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MKLM6_RS16920 f1f9b65f8e42d2e00350a1bbc8475490 246 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 57 79 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MKLM6_RS01410 e03d33fbb930ab6f5f7d4e8bc46b8e76 70 SUPERFAMILY SSF143100 1 63 2.62E-20 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like MKLM6_RS01410 e03d33fbb930ab6f5f7d4e8bc46b8e76 70 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 3 66 4.1E-14 T 28-03-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system MKLM6_RS01410 e03d33fbb930ab6f5f7d4e8bc46b8e76 70 Gene3D G3DSA:3.30.2390.10 1 69 9.8E-18 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like MKLM6_RS22275 9b417fca5c90af238ad76a20f8c639ea 202 Gene3D G3DSA:1.10.3540.10 4 192 1.8E-58 T 28-03-2018 MKLM6_RS22275 9b417fca5c90af238ad76a20f8c639ea 202 Pfam PF08849 Putative inner membrane protein (DUF1819) 5 182 7.2E-55 T 28-03-2018 IPR014948 Protein of unknown function DUF1819, putative inner membrane MKLM6_RS01880 afbf98b68bb7ea42291f20959ef154c2 254 Gene3D G3DSA:2.60.120.380 18 201 2.3E-6 T 28-03-2018 MKLM6_RS01880 afbf98b68bb7ea42291f20959ef154c2 254 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 50 156 2.8E-5 T 28-03-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial MKLM6_RS04620 553fb5bf2cc4478d55f1d8e9ea2cb8f0 147 Pfam PF04246 Positive regulator of sigma(E), RseC/MucC 13 141 1.3E-22 T 28-03-2018 IPR007359 Positive regulator of sigma(E), RseC/MucC MKLM6_RS04620 553fb5bf2cc4478d55f1d8e9ea2cb8f0 147 PIRSF PIRSF004923 1 147 1.1E-25 T 28-03-2018 IPR026268 Protein RseC MKLM6_RS06330 7362d5128d78cb1a54238dcce1bcf883 287 Gene3D G3DSA:3.90.550.10 3 218 2.6E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS06330 7362d5128d78cb1a54238dcce1bcf883 287 Pfam PF00535 Glycosyl transferase family 2 8 161 1.3E-29 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MKLM6_RS06330 7362d5128d78cb1a54238dcce1bcf883 287 SUPERFAMILY SSF53448 3 237 5.35E-43 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MKLM6_RS11715 757afb6f2eec1d4f0c0b8c59dcf47757 995 Pfam PF13700 Domain of unknown function (DUF4158) 6 160 2.5E-30 T 28-03-2018 IPR025296 Domain of unknown function DUF4158 MKLM6_RS11715 757afb6f2eec1d4f0c0b8c59dcf47757 995 Pfam PF01526 Tn3 transposase DDE domain 591 977 1.7E-140 T 28-03-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 MKLM6_RS22110 fad841a29b50a4f0732c3b3b8d3fb49a 298 Gene3D G3DSA:3.40.50.1820 66 289 9.9E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS22110 fad841a29b50a4f0732c3b3b8d3fb49a 298 SUPERFAMILY SSF53474 75 227 3.54E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS11200 11c23d2fc5480f670ca3800f9fb3b711 452 Pfam PF13559 Domain of unknown function (DUF4129) 376 445 8.4E-6 T 28-03-2018 IPR025403 Domain of unknown function DUF4129 MKLM6_RS14695 417f0c1bddee064d65771fece9945796 347 Pfam PF05987 Bacterial protein of unknown function (DUF898) 9 340 1.6E-106 T 28-03-2018 IPR010295 Protein of unknown function DUF898 MKLM6_RS17510 e1beddf820273b45e36258aa19f5331f 189 Gene3D G3DSA:1.10.490.10 8 175 1.1E-22 T 28-03-2018 MKLM6_RS01275 aa9cc9d257c61a2f36fabbb49ea12593 235 Pfam PF10677 Protein of unknown function (DUF2490) 30 218 1.6E-41 T 28-03-2018 IPR019619 Protein of unknown function DUF2490 MKLM6_RS01275 aa9cc9d257c61a2f36fabbb49ea12593 235 Gene3D G3DSA:2.40.160.20 21 134 0.0062 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MKLM6_RS01275 aa9cc9d257c61a2f36fabbb49ea12593 235 Gene3D G3DSA:2.40.160.20 183 235 0.046 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MKLM6_RS05045 d99943482f485df63a23f7e833773d05 408 SUPERFAMILY SSF53474 160 303 1.81E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS05045 d99943482f485df63a23f7e833773d05 408 SUPERFAMILY SSF53474 38 88 1.81E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS05045 d99943482f485df63a23f7e833773d05 408 Gene3D G3DSA:3.40.50.1820 4 402 9.6E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold MKLM6_RS11890 13be344db5612b4276ad0b0dcead9737 180 Gene3D G3DSA:3.30.1450.10 37 108 3.7E-10 T 28-03-2018 MKLM6_RS11890 13be344db5612b4276ad0b0dcead9737 180 Pfam PF04355 SmpA / OmlA family 37 102 5.6E-23 T 28-03-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 MKLM6_RS11890 13be344db5612b4276ad0b0dcead9737 180 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 6 137 35.004 T 28-03-2018 IPR026592 Outer membrane protein assembly factor BamE MKLM6_RS06260 79242c9e6579c6347bd998b44c3dac05 307 Pfam PF12275 Protein of unknown function (DUF3616) 15 92 1.9E-4 T 28-03-2018 IPR022060 Protein of unknown function DUF3616 MKLM6_RS06260 79242c9e6579c6347bd998b44c3dac05 307 Pfam PF12275 Protein of unknown function (DUF3616) 122 256 1.4E-6 T 28-03-2018 IPR022060 Protein of unknown function DUF3616 MKLM6_RS16375 8cce0d903730fddd1cc27617c9e05869 112 Pfam PF11006 Protein of unknown function (DUF2845) 24 107 1.6E-23 T 28-03-2018 IPR021268 Protein of unknown function DUF2845 MKLM6_RS02810 69943a7c817f428efa22b7673aecc46e 139 Pfam PF10975 Protein of unknown function (DUF2802) 58 135 3.6E-15 T 28-03-2018 IPR021244 Protein of unknown function DUF2802 MKLM6_RS05515 6e5a2620471775f53c102776e8e1bc8d 532 Pfam PF00916 Sulfate permease family 12 395 4.0E-56 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MKLM6_RS17205 36f93033e7a1a1d5afb5f928bb287504 210 Pfam PF04367 Protein of unknown function (DUF502) 76 166 2.5E-21 T 28-03-2018 IPR007462 Protein of unknown function DUF502 MKLM6_RS05165 d95bb6ec3710f235f8f693c451a6f822 147 PIRSF PIRSF034445 5 147 2.6E-21 T 28-03-2018 IPR012899 LTXXQ motif family protein GO:0042597 MKLM6_RS05165 d95bb6ec3710f235f8f693c451a6f822 147 Pfam PF07813 LTXXQ motif family protein 42 140 1.1E-10 T 28-03-2018 IPR012899 LTXXQ motif family protein GO:0042597 MKLM6_RS12235 3ebbb961ba69407a85f6c92e53320380 332 Pfam PF01609 Transposase DDE domain 131 320 6.8E-33 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MKLM6_RS12235 3ebbb961ba69407a85f6c92e53320380 332 Pfam PF05598 Transposase domain (DUF772) 45 118 4.1E-19 T 28-03-2018 IPR008490 Transposase InsH, N-terminal MKLM6_RS03050 e2bcb5309836f1a709dfa550c5604f7d 293 Pfam PF02517 CAAX protease self-immunity 121 238 8.6E-11 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 MKLM6_RS15450 6596a1990888c21e9f6a62c7160c1f9a 475 SUPERFAMILY SSF56059 45 210 1.66E-63 T 28-03-2018 MKLM6_RS15450 6596a1990888c21e9f6a62c7160c1f9a 475 SUPERFAMILY SSF56059 317 462 1.66E-63 T 28-03-2018 MKLM6_RS15450 6596a1990888c21e9f6a62c7160c1f9a 475 Gene3D G3DSA:3.30.470.20 335 465 7.8E-7 T 28-03-2018 MKLM6_RS15450 6596a1990888c21e9f6a62c7160c1f9a 475 PIRSF PIRSF005522 1 474 8.4E-230 T 28-03-2018 IPR016450 Uncharacterised conserved protein UCP005522 MKLM6_RS15450 6596a1990888c21e9f6a62c7160c1f9a 475 Pfam PF14403 Circularly permuted ATP-grasp type 2 73 447 2.7E-164 T 28-03-2018 IPR025841 Circularly permuted ATP-grasp type 2 MKLM6_RS11135 b4452332f1a05c5efa4ef4fb102ad1d2 162 SUPERFAMILY SSF46565 105 160 2.22E-13 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS11135 b4452332f1a05c5efa4ef4fb102ad1d2 162 Gene3D G3DSA:1.10.287.110 107 161 1.4E-12 T 28-03-2018 IPR001623 DnaJ domain MKLM6_RS06565 5b25939559e09a3fca436b29a737e0ed 453 Gene3D G3DSA:2.60.120.260 96 198 0.015 T 28-03-2018 IPR008979 Galactose-binding domain-like MKLM6_RS22520 eb935dcf1f03c5fcc6acc7b90709510d 354 Pfam PF06834 TraU protein 40 352 5.9E-90 T 28-03-2018 IPR009649 TraU MKLM6_RS01405 cf2539ce096a664347e20f1a75d796de 66 Pfam PF04324 BFD-like [2Fe-2S] binding domain 12 61 1.1E-11 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain MKLM6_RS17600 f8936d80a1f4f05508779b19519a9a86 101 SUPERFAMILY SSF158757 2 77 1.07E-35 T 28-03-2018 IPR023163 SMc04008-like domain MKLM6_RS17600 f8936d80a1f4f05508779b19519a9a86 101 Gene3D G3DSA:1.10.3340.10 1 83 2.5E-41 T 28-03-2018 IPR023163 SMc04008-like domain MKLM6_RS17600 f8936d80a1f4f05508779b19519a9a86 101 Pfam PF06844 Protein of unknown function (DUF1244) 27 92 3.4E-37 T 28-03-2018 IPR023163 SMc04008-like domain MKLM6_RS22575 5b8dcba5c59bb9340afb94a616e8c73c 205 Pfam PF05309 TraE protein 1 178 9.8E-29 T 28-03-2018 IPR007973 Pilus assembly TraE GO:0000746 MKLM6_RS01710 09b106a8479bda8c833232525bcc06eb 63 Pfam PF11174 Protein of unknown function (DUF2970) 6 61 2.2E-20 T 28-03-2018 IPR021344 Protein of unknown function DUF2970 MKLM6_RS00745 cde7ece767a0275a91aa4c2584fe9561 192 Gene3D G3DSA:2.60.120.260 67 192 2.4E-6 T 28-03-2018 IPR008979 Galactose-binding domain-like MKLM6_RS21140 085008f3aba7cd1cd3f005def0a06170 136 Pfam PF02472 Biopolymer transport protein ExbD/TolR 12 134 2.0E-29 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 MKLM6_RS12060 2ac67006d4b1886f5e05e8496b2ad1bd 234 Gene3D G3DSA:1.25.40.10 36 232 8.5E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MKLM6_RS12765 ebedc8601971e079deb32ea717197ce7 66 Pfam PF04328 Selenoprotein, putative 13 66 1.6E-15 T 28-03-2018 IPR007423 Selenoprotein, putative MKLM6_RS15115 42bd08d9df14abc92a5099f8a01d22a4 65 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 50 4.0E-10 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain MKLM6_RS21490 57ffdc69ef7735764b54fac2d9109ef7 114 Pfam PF09842 Predicted membrane protein (DUF2069) 9 108 5.8E-28 T 28-03-2018 IPR018643 Protein of unknown function DUF2069, membrane MKLM6_RS05555 f619ab0a9740c7a303e09ae329756e69 79 SUPERFAMILY SSF53850 1 77 1.37E-6 T 28-03-2018 MKLM6_RS05555 f619ab0a9740c7a303e09ae329756e69 79 Gene3D G3DSA:3.40.190.10 10 78 1.2E-11 T 28-03-2018 MKLM6_RS07725 73c95c08a765226262d70c02a497c032 110 SUPERFAMILY SSF103481 33 108 1.11E-5 T 28-03-2018 MKLM6_RS09510 e6b8feaeec184ea4ceef77b975ccf8d6 117 Gene3D G3DSA:1.10.1660.10 7 117 1.4E-26 T 28-03-2018 MKLM6_RS09510 e6b8feaeec184ea4ceef77b975ccf8d6 117 Pfam PF13411 MerR HTH family regulatory protein 19 87 9.7E-23 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MKLM6_RS09510 e6b8feaeec184ea4ceef77b975ccf8d6 117 SMART SM00422 19 89 1.8E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MKLM6_RS09510 e6b8feaeec184ea4ceef77b975ccf8d6 117 SUPERFAMILY SSF46955 17 116 3.75E-19 T 28-03-2018 IPR009061 Putative DNA-binding domain MKLM6_RS01755 fabfad06e148a2721348ec28b208834c 316 Pfam PF01882 Protein of unknown function DUF58 213 290 1.2E-15 T 28-03-2018 IPR002881 Domain of unknown function DUF58 MKLM6_RS06860 1964efa9e14f9ee4c771732d176eaecf 172 Pfam PF02620 Uncharacterized ACR, COG1399 59 168 1.6E-18 T 28-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD MKLM6_RS18735 d0910e7d1e60ecef3f56d39ed3236c1e 287 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 49 212 1.8E-10 T 28-03-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system MKLM6_RS02965 58bfeef1401290e79c037816dd7d72e8 115 Pfam PF11191 Protein of unknown function (DUF2782) 27 112 7.4E-32 T 28-03-2018 IPR021357 Protein of unknown function DUF2782 MKLM6_RS13835 6a325ba7f44e5c317bc418ea41c706b3 250 Pfam PF00899 ThiF family 12 238 1.9E-35 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MKLM6_RS13835 6a325ba7f44e5c317bc418ea41c706b3 250 Gene3D G3DSA:3.40.50.720 2 250 1.4E-46 T 28-03-2018 MKLM6_RS13835 6a325ba7f44e5c317bc418ea41c706b3 250 SUPERFAMILY SSF69572 3 241 2.49E-60 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MKLM6_RS08225 a58c7716f7ae98230d0eb2baf390b97f 128 Gene3D G3DSA:1.20.120.10 26 126 3.5E-8 T 28-03-2018 MKLM6_RS08225 a58c7716f7ae98230d0eb2baf390b97f 128 SUPERFAMILY SSF47175 29 126 4.97E-8 T 28-03-2018 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 MKLM6_RS15765 7ce0b4bb309c40368ac380c10e65762f 361 Pfam PF01757 Acyltransferase family 37 333 4.1E-15 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 MKLM6_RS14465 314972dc32925f6f93b30f261cfad6d7 388 TIGRFAM TIGR02913 HAF_rpt: probable extracellular repeat, HAF family 75 112 1.4E-12 T 28-03-2018 IPR014262 Extracellular HAF MKLM6_RS14465 314972dc32925f6f93b30f261cfad6d7 388 TIGRFAM TIGR02913 HAF_rpt: probable extracellular repeat, HAF family 194 231 1.2E-8 T 28-03-2018 IPR014262 Extracellular HAF MKLM6_RS14465 314972dc32925f6f93b30f261cfad6d7 388 TIGRFAM TIGR02913 HAF_rpt: probable extracellular repeat, HAF family 283 319 5.0E-10 T 28-03-2018 IPR014262 Extracellular HAF MKLM6_RS14465 314972dc32925f6f93b30f261cfad6d7 388 TIGRFAM TIGR02913 HAF_rpt: probable extracellular repeat, HAF family 237 277 7.6E-11 T 28-03-2018 IPR014262 Extracellular HAF MKLM6_RS14465 314972dc32925f6f93b30f261cfad6d7 388 TIGRFAM TIGR02913 HAF_rpt: probable extracellular repeat, HAF family 119 151 9.1E-6 T 28-03-2018 IPR014262 Extracellular HAF MKLM6_RS01375 46d3deeb2cb9478583bed1e50cda0fa8 217 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 179 210 0.0029 T 28-03-2018 MKLM6_RS05030 f42b06a58d9a4bea3289358da2544db5 199 Pfam PF10973 Protein of unknown function (DUF2799) 43 125 2.3E-22 T 28-03-2018 IPR021242 Protein of unknown function DUF2799 MKLM6_RS17280 c34b241e7a0d74d1e5708849f5449072 242 Pfam PF13723 Beta-ketoacyl synthase, N-terminal domain 23 239 2.2E-47 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MKLM6_RS21260 5f25d8023469b2fa8e07af73e8afa64f 541 Gene3D G3DSA:3.40.190.10 249 439 6.0E-7 T 28-03-2018 MKLM6_RS21925 74e68ba7d619ff44a78bc585cae2953a 340 SUPERFAMILY SSF117892 132 236 7.85E-6 T 28-03-2018 IPR001107 Band 7 domain MKLM6_RS21925 74e68ba7d619ff44a78bc585cae2953a 340 Pfam PF13421 SPFH domain-Band 7 family 33 236 1.1E-41 T 28-03-2018 IPR033880 SPFH domain, YdjI-like MKLM6_RS02270 12b3f4fb1c05bcbf3afbf23b0396de99 256 Gene3D G3DSA:1.20.120.330 41 187 1.9E-4 T 28-03-2018 MKLM6_RS17110 0c9d0246744170ac9a4f4117ece99f48 241 Gene3D G3DSA:3.30.70.60 95 229 5.3E-4 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 MKLM6_RS02140 419a98df1fc521269cdc5667685d1f68 155 Pfam PF14316 Domain of unknown function (DUF4381) 5 150 1.6E-41 T 28-03-2018 IPR025489 Protein of unknown function (DUF4381 MKLM6_RS13020 c5114e9adf570df488c47570f6fea3ba 92 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 34 81 1.7E-5 T 28-03-2018 IPR010260 DNA-binding transcriptional activator AlpA MKLM6_RS03125 2981eda4a031a9efb4b1160433ebbc3b 124 Pfam PF07798 Protein of unknown function (DUF1640) 6 47 4.9E-7 T 28-03-2018 IPR024461 Coiled-coil domain-containing protein 90-like MKLM6_RS19725 77946cc9ca323ca3f25871e9c9caa830 238 Pfam PF07603 Protein of unknown function (DUF1566) 31 206 2.1E-11 T 28-03-2018 IPR011460 Protein of unknown function DUF1566 MKLM6_RS17405 671f865032baab9eca97f49d14eaabf1 254 Pfam PF05484 LRV protein FeS4 cluster 14 56 3.7E-13 T 28-03-2018 IPR008665 LRV FeS4 cluster MKLM6_RS17405 671f865032baab9eca97f49d14eaabf1 254 Gene3D G3DSA:1.25.10.10 4 245 1.9E-32 T 28-03-2018 IPR011989 Armadillo-like helical MKLM6_RS17405 671f865032baab9eca97f49d14eaabf1 254 SUPERFAMILY SSF48371 27 237 7.97E-41 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 MKLM6_RS07590 c6f2f49a85e414c3593a7424efa61e49 415 Pfam PF00872 Transposase, Mutator family 13 383 7.4E-67 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 MKLM6_RS14690 0b2078f0a905694c9a1156bd503a5231 333 Gene3D G3DSA:3.30.2010.10 121 236 7.3E-15 T 28-03-2018 MKLM6_RS14690 0b2078f0a905694c9a1156bd503a5231 333 Pfam PF01435 Peptidase family M48 183 332 5.4E-24 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MKLM6_RS04935 765c1486e2f373e146c7252528a85bb4 175 Pfam PF06146 Phosphate-starvation-inducible E 92 160 2.8E-16 T 28-03-2018 IPR020948 Phosphate-starvation-induced PsiE-like MKLM6_RS01230 d3908c2900373b9cec10b6bacb1f5013 365 Pfam PF13795 HupE / UreJ protein 187 335 6.7E-46 T 28-03-2018 IPR032809 Putative HupE/UreJ protein MKLM6_RS16345 0d55b00a93ac82916fcbfd0b21fa6966 402 Gene3D G3DSA:1.20.120.330 30 178 1.1E-5 T 28-03-2018 MKLM6_RS20435 48229e79a20fae62524d151a5f4afa22 453 Pfam PF03600 Citrate transporter 52 401 7.6E-45 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 MKLM6_RS19305 610054cbdbd08749bf27c8746f6df769 56 Pfam PF09720 Putative addiction module component 3 49 1.8E-14 T 28-03-2018 IPR013406 Conserved hypothetical protein CHP02574, addiction module MKLM6_RS03965 0b361633f4e15fbfba1528731c585c98 262 Pfam PF00263 Bacterial type II and III secretion system protein 132 236 1.3E-6 T 28-03-2018 IPR004846 Type II/III secretion system GO:0009306 MKLM6_RS03965 0b361633f4e15fbfba1528731c585c98 262 Pfam PF03958 Bacterial type II/III secretion system short domain 25 81 8.8E-7 T 28-03-2018 IPR005644 NolW-like MKLM6_RS00365 1631807f6ee9de407781137aa89d7168 223 Pfam PF09335 SNARE associated Golgi protein 69 181 5.2E-23 T 28-03-2018 IPR032816 SNARE associated Golgi protein MKLM6_RS07870 aa5c55d47f643ca2ac4c951b167c1dcd 539 Pfam PF14224 Domain of unknown function (DUF4331) 32 507 1.2E-110 T 28-03-2018 IPR025566 Protein of unknown function DUF4331 MKLM6_RS06385 d75b56054fd8dbdf5bb7199c21682620 336 Pfam PF04333 MlaA lipoprotein 51 236 3.9E-69 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 MKLM6_RS06385 d75b56054fd8dbdf5bb7199c21682620 336 PRINTS PR01805 VacJ lipoprotein signature 51 64 3.9E-26 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 MKLM6_RS06385 d75b56054fd8dbdf5bb7199c21682620 336 PRINTS PR01805 VacJ lipoprotein signature 155 172 3.9E-26 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 MKLM6_RS06385 d75b56054fd8dbdf5bb7199c21682620 336 PRINTS PR01805 VacJ lipoprotein signature 119 136 3.9E-26 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 MKLM6_RS06385 d75b56054fd8dbdf5bb7199c21682620 336 PRINTS PR01805 VacJ lipoprotein signature 68 84 3.9E-26 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 MKLM6_RS14850 773d7f7ec4f665d78ba7c7e8a8371502 495 Pfam PF13372 Alginate export 73 481 3.0E-79 T 28-03-2018 IPR025388 Alginate export domain MKLM6_RS12780 30ce2baceeafddaad1ff049dfa32db07 438 Pfam PF03929 PepSY-associated TM region 24 381 2.3E-56 T 28-03-2018 IPR005625 PepSY-associated TM protein MKLM6_RS10200 1c02b90414dd49be192d30c0bfd481c0 403 Pfam PF01757 Acyltransferase family 44 371 3.5E-25 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 MKLM6_RS08055 cae81ba8816d888f415b8fc43c5c7bae 311 Pfam PF16162 Domain of unknown function (DUF4868) 115 298 1.3E-39 T 28-03-2018 IPR032359 Protein of unknown function DUF4868 MKLM6_RS21045 b08461bdca11d1df4cc2720453b8fbcd 234 Gene3D G3DSA:2.40.170.20 117 186 2.6E-4 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MKLM6_RS17850 ad61173a69b755e19e0f849ebbcc87ac 225 Gene3D G3DSA:2.60.40.1120 143 217 2.2E-5 T 28-03-2018 MKLM6_RS03560 b57183a4ffbe1ef31c5e1dc6fb576cb1 280 Gene3D G3DSA:3.40.50.720 2 275 1.8E-25 T 28-03-2018 MKLM6_RS03560 b57183a4ffbe1ef31c5e1dc6fb576cb1 280 SUPERFAMILY SSF51735 4 273 1.37E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain MKLM6_RS03560 b57183a4ffbe1ef31c5e1dc6fb576cb1 280 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 189 1.6E-7 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MKLM6_RS04155 eca3d37174d51b123517571d94d399a0 50 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 11 45 1.8E-5 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MKLM6_RS14625 d9bf3c787cb51e373e9dfa8df656c239 182 Pfam PF02830 V4R domain 121 179 1.7E-15 T 28-03-2018 IPR004096 4-vinyl reductase, 4VR MKLM6_RS14625 d9bf3c787cb51e373e9dfa8df656c239 182 SMART SM00989 119 181 9.5E-15 T 28-03-2018 IPR004096 4-vinyl reductase, 4VR MKLM6_RS14625 d9bf3c787cb51e373e9dfa8df656c239 182 Gene3D G3DSA:3.30.1380.20 10 182 1.7E-25 T 28-03-2018 MKLM6_RS14625 d9bf3c787cb51e373e9dfa8df656c239 182 SUPERFAMILY SSF111126 24 179 1.1E-21 T 28-03-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain MKLM6_RS02000 929b25b2dd12987c447332dcd0a953fc 348 TIGRFAM TIGR03790 TIGR03790: TIGR03790 family protein 38 325 1.3E-74 T 28-03-2018 IPR022265 Conserved hypothetical protein CHP03790 MKLM6_RS13775 8f56ae5bc44cddfa5f128b71cb5d33b1 251 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 224 246 1.7E-4 T 28-03-2018 IPR013424 PEP-CTERM protein-sorting domain MKLM6_RS13775 8f56ae5bc44cddfa5f128b71cb5d33b1 251 Pfam PF07589 PEP-CTERM motif 223 245 7.2E-6 T 28-03-2018 IPR013424 PEP-CTERM protein-sorting domain MKLM6_RS09565 846a222dcb17d674eefb4152ef8ab956 130 Pfam PF14346 Domain of unknown function (DUF4398) 24 122 2.6E-28 T 28-03-2018 IPR025511 Domain of unknown function DUF4398 MKLM6_RS06620 d65895fc23bd954bb5a1a1578048c3dc 180 TIGRFAM TIGR02548 casB_cse2: CRISPR type I-E/ECOLI-associated protein CasB/Cse2 24 166 1.3E-12 T 28-03-2018 IPR013382 CRISPR-associated protein Cse2 MKLM6_RS11340 5870e6002a0c469627099bd54af13280 192 Pfam PF10741 Type II secretion system (T2SS), protein M subtype b 80 187 6.9E-24 T 28-03-2018 IPR034756 Type II secretion system (T2SS), protein M subtype b MKLM6_RS11340 5870e6002a0c469627099bd54af13280 192 Gene3D G3DSA:3.30.70.60 84 191 5.1E-8 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 MKLM6_RS06970 cf1d63a8b9249832bd1146406fb5c9a3 85 Pfam PF11127 Protein of unknown function (DUF2892) 12 69 1.5E-14 T 28-03-2018 IPR021309 Protein of unknown function DUF2892 MKLM6_RS12490 6a7772684e547695f5702186241fa1c6 307 Gene3D G3DSA:3.30.460.10 88 216 3.2E-4 T 28-03-2018 MKLM6_RS17740 5532eacae4fdfd75ffea3be1435e5bfd 88 Pfam PF10047 Protein of unknown function (DUF2281) 7 46 6.4E-6 T 28-03-2018 IPR018739 Domain of unknown function DUF2281 MKLM6_RS12370 4aa2865d55794854913147a693e94c3d 119 ProSitePatterns PS00202 Rubredoxin signature. 105 115 - T 28-03-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 MKLM6_RS22145 45b90c79b15cdb8eb2af8591117a6eb0 309 Gene3D G3DSA:1.10.287.620 213 307 0.0043 T 28-03-2018 MKLM6_RS22145 45b90c79b15cdb8eb2af8591117a6eb0 309 Gene3D G3DSA:1.10.287.620 73 212 2.0E-5 T 28-03-2018 MKLM6_RS22145 45b90c79b15cdb8eb2af8591117a6eb0 309 Pfam PF11740 Plasmid replication region DNA-binding N-term 15 120 5.5E-17 T 28-03-2018 IPR021104 KfrA, N-terminal DNA-binding domain MKLM6_RS04140 975b0e3ea26119aadc3062ba8049c859 83 Pfam PF03683 Uncharacterised protein family (UPF0175) 16 78 3.1E-9 T 28-03-2018 IPR005368 Uncharacterised protein family UPF0175 MKLM6_RS21365 0120e6696159c164c59a15f1390192ea 184 Pfam PF09831 Uncharacterized protein conserved in bacteria (DUF2058) 8 184 5.8E-60 T 28-03-2018 IPR018636 Protein of unknown function DUF2058 MKLM6_RS04395 12ca49fa37a7497b094afb5b980dfd81 376 Pfam PF00487 Fatty acid desaturase 57 348 3.6E-25 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 MKLM6_RS22490 345cb773643fa29c5a96cb98dfda3dd5 482 Pfam PF06122 Conjugative relaxosome accessory transposon protein 30 397 1.4E-101 T 28-03-2018 IPR010927 Type IV conjugative transfer system protein TraH MKLM6_RS11120 9f80a8cd60498fdb35fc42e74e1600dd 242 Pfam PF12119 Protein of unknown function (DUF3581) 1 216 2.2E-99 T 28-03-2018 IPR021974 Protein of unknown function DUF3581 MKLM6_RS14875 284cc74586f34e7dbdd6422e44f9f060 227 Gene3D G3DSA:3.40.190.10 1 190 4.0E-5 T 28-03-2018 MKLM6_RS08345 d4b4a160f5aa87b6b84445101df2cf0d 164 Pfam PF07087 Protein of unknown function (DUF1353) 3 75 3.0E-22 T 28-03-2018 IPR010767 Campylobacter phage CGC-2007, Cje0229 MKLM6_RS07790 2420497f06715d572cb970a03911a904 501 SUPERFAMILY SSF56801 50 273 1.44E-5 T 28-03-2018 MKLM6_RS07790 2420497f06715d572cb970a03911a904 501 Gene3D G3DSA:3.40.50.980 102 359 4.3E-4 T 28-03-2018 MKLM6_RS03325 f144107d5fd9fe6d7776e866ac79fb4d 236 Pfam PF16357 Putative PepSY_TM-like 38 228 2.1E-11 T 28-03-2018 IPR032307 Putative PepSY TM-like protein MKLM6_RS22370 b750c1483e8e1d5eabea13053a7f7b55 210 Pfam PF14348 Domain of unknown function (DUF4400) 30 200 1.7E-21 T 28-03-2018 IPR022266 Integrating conjugative element protein, PFL4697-type MKLM6_RS10900 c5c7ea038e584a099edded034029bf94 151 Pfam PF03918 Cytochrome C biogenesis protein 7 145 5.9E-53 T 28-03-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family MKLM6_RS19690 fef13b4da94b575f3fbff4430567040f 141 Pfam PF09335 SNARE associated Golgi protein 41 139 3.2E-8 T 28-03-2018 IPR032816 SNARE associated Golgi protein MKLM6_RS21305 08284f96056257fa1cd3ceffd9d9d913 168 TIGRFAM TIGR03352 VI_chp_3: type VI secretion lipoprotein, VC_A0113 family 6 150 1.8E-37 T 28-03-2018 IPR017734 Type VI secretion system, lipoprotein SciN MKLM6_RS21305 08284f96056257fa1cd3ceffd9d9d913 168 Pfam PF12790 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 14 148 5.0E-36 T 28-03-2018 IPR017734 Type VI secretion system, lipoprotein SciN MKLM6_RS06190 8d45a18103c759992c83138f46691bfd 76 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 31 67 1.3E-6 T 28-03-2018 IPR010260 DNA-binding transcriptional activator AlpA MKLM6_RS18000 61f512bdd7824efb6ac7841e77e0186c 113 Pfam PF05400 Flagellar protein FliT 30 110 6.4E-9 T 28-03-2018 IPR008622 Flagellar protein FliT MKLM6_RS01620 796e7c354353c21b372ea92050095ecb 119 Pfam PF04241 Protein of unknown function (DUF423) 19 102 1.2E-29 T 28-03-2018 IPR006696 Protein of unknown function DUF423 MKLM6_RS19610 66ddf854ffcc763ef25439b33d027085 238 Pfam PF13689 Domain of unknown function (DUF4154) 90 232 8.9E-41 T 28-03-2018 IPR025293 Protein of unknown function DUF4154 MKLM6_RS16640 27aa1dee7fcd105c9470f06360922d04 190 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 79 167 2.1E-18 T 28-03-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 MKLM6_RS11565 55366d27f5a01e31c1f45c15ac605c19 301 Pfam PF13280 WYL domain 114 246 5.1E-10 T 28-03-2018 IPR026881 WYL domain MKLM6_RS11565 55366d27f5a01e31c1f45c15ac605c19 301 PIRSF PIRSF015558 1 281 1.0E-91 T 28-03-2018 IPR016634 WYL domain protein, s026 type MKLM6_RS05595 a782c775b12e2e43fc16633be6e6782f 272 Pfam PF06468 Spondin_N 43 184 2.3E-7 T 28-03-2018 IPR009465 Spondin, N-terminal Reactome: R-HSA-5083635|Reactome: R-HSA-5173214 MKLM6_RS10265 e8dd7665620804d30b405194c557c512 246 Pfam PF09335 SNARE associated Golgi protein 76 193 7.1E-26 T 28-03-2018 IPR032816 SNARE associated Golgi protein MKLM6_RS15750 001a23c63fc749389bc1d1eaa9c09b08 392 Pfam PF04230 Polysaccharide pyruvyl transferase 33 332 4.7E-29 T 28-03-2018 IPR007345 Polysaccharide pyruvyl transferase MKLM6_RS09995 a3658cf5c89978c0e2333dd06625b361 138 Pfam PF04143 Sulphur transport 10 126 8.8E-9 T 28-03-2018 IPR007272 Sulphur transport domain MKLM6_RS09605 824f5fb46bba1596d8cc9cdcb9ce8379 43 Pfam PF11295 Protein of unknown function (DUF3096) 7 42 6.7E-17 T 28-03-2018 IPR021446 Protein of unknown function DUF3096 MKLM6_RS09225 1f0101204731323100143d809f0aaf37 79 Hamap MF_00404 Probable oxaloacetate decarboxylase gamma chain [oadG]. 1 79 25.485 T 28-03-2018 IPR023424 Oxaloacetate decarboxylase gamma chain, probable GO:0008948 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 MKLM6_RS09225 1f0101204731323100143d809f0aaf37 79 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 4 76 8.4E-17 T 28-03-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0071436 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 MKLM6_RS09225 1f0101204731323100143d809f0aaf37 79 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 8 73 1.7E-14 T 28-03-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0071436 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 MKLM6_RS06975 35597a496184554dac9a28e247d1eb4d 146 Pfam PF04186 FxsA cytoplasmic membrane protein 10 114 3.8E-36 T 28-03-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 MKLM6_RS19485 57ea1a53d952630a0c60c745ab81ab54 138 Pfam PF05656 Protein of unknown function (DUF805) 3 105 2.5E-6 T 28-03-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 MKLM6_RS12980 ff80e0b6eee22c7482f404287fbd92b1 85 Gene3D G3DSA:3.30.920.30 18 85 4.4E-4 T 28-03-2018 MKLM6_RS00845 b87956ae02d4239c12daa13f513bd45f 246 Pfam PF04730 Agrobacterium VirD5 protein 41 222 1.4E-18 T 28-03-2018 IPR006819 Agrobacterium VirD5 protein MKLM6_RS04255 c09986c1d1ea21813b1c48a2b1564fcf 379 Pfam PF11651 P22 coat protein - gene protein 5 78 264 2.4E-10 T 28-03-2018 IPR024659 Major capsid protein Gp5 MKLM6_RS14920 00e4d5b87bbad87acb47622dc7b5db4d 246 Gene3D G3DSA:1.20.1250.20 1 229 0.0015 T 28-03-2018 MKLM6_RS22525 5aa53663720ffb8e346546336bf49473 388 Pfam PF09673 Type-F conjugative transfer system pilin assembly protein 88 175 9.5E-12 T 28-03-2018 IPR019106 Type-F conjugative transfer system pilin assembly protein TrbC MKLM6_RS00830 dac26f99050609c76ac8ff99baeb0965 166 Pfam PF03692 Putative zinc- or iron-chelating domain 27 110 1.9E-7 T 28-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein MKLM6_RS01820 4ee097040d049d8850a25aa4892b564d 147 Pfam PF04353 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ 9 145 1.1E-30 T 28-03-2018 IPR007448 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ GO:0006355 MKLM6_RS04720 305f19c26731052e21b53cbee8d0656b 201 Pfam PF13707 RloB-like protein 22 188 1.8E-28 T 28-03-2018 IPR025591 RloB-like protein MKLM6_RS19185 2b14bef3bf8093b56aebc93f07b562da 279 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 254 276 2.7E-4 T 28-03-2018 IPR013424 PEP-CTERM protein-sorting domain MKLM6_RS07315 e3b500f5eb4f222e43d299e326a997a1 175 Pfam PF03880 DbpA RNA binding domain 85 155 1.3E-16 T 28-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain MKLM6_RS22545 1688eaf33f12334cf0da15da420ade89 62 Pfam PF14239 RRXRR protein 15 60 1.3E-8 T 28-03-2018 IPR025938 RRXRR domain MKLM6_RS04305 53794a5fa49a402e05ee4e8bb401db38 350 Pfam PF06114 IrrE N-terminal-like domain 143 270 7.3E-21 T 28-03-2018 IPR010359 IrrE N-terminal-like domain MKLM6_RS17200 e214451d587333ddce4d9f8251b2a191 212 Pfam PF09601 Protein of unknown function (DUF2459) 35 193 1.3E-33 T 28-03-2018 IPR011727 Conserved hypothetical protein CHP02117 MKLM6_RS14320 192ff5eafef65869eaa474f9e2402c99 158 Pfam PF07681 DoxX 33 113 1.4E-16 T 28-03-2018 IPR032808 DoxX family MKLM6_RS16290 f53d87a4007ed504099f4402cad2e50c 245 Pfam PF08797 HIRAN domain 125 201 2.1E-7 T 28-03-2018 IPR014905 HIRAN domain GO:0003676|GO:0008270|GO:0016818 Reactome: R-HSA-8866654 MKLM6_RS16290 f53d87a4007ed504099f4402cad2e50c 245 SMART SM00910 123 223 5.0E-5 T 28-03-2018 IPR014905 HIRAN domain GO:0003676|GO:0008270|GO:0016818 Reactome: R-HSA-8866654 MKLM6_RS19465 947d0093d488e6b80adeb2e05204d5af 122 Pfam PF13648 Lipocalin-like domain 25 109 4.4E-5 T 28-03-2018 IPR024311 Lipocalin-like domain MKLM6_RS10430 8bde18773cb07bdd6b7bc49fb8dfb0fa 570 Gene3D G3DSA:3.40.190.10 267 457 1.5E-9 T 28-03-2018 MKLM6_RS14160 9814f1df1aadcc79466c8a5e59f328d6 61 Gene3D G3DSA:1.10.1220.10 3 51 1.1E-4 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 MKLM6_RS13630 adf4d1b06e8cd16708d7ae31a456e4d3 163 Pfam PF06723 MreB/Mbl protein 22 142 4.9E-11 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MKLM6_RS06170 fca018dab5474032b72bb3d2385c3e9e 103 Gene3D G3DSA:1.10.287.1060 5 75 0.0012 T 28-03-2018 MKLM6_RS09365 c8842cd3882afd73c197060197a91c54 215 Pfam PF10816 Domain of unknown function (DUF2760) 92 214 8.0E-55 T 28-03-2018 IPR021212 Domain of unknown function DUF2760 MKLM6_RS11230 a27429fcde7caed83bdc756f816d7787 367 Pfam PF14307 Glycosyltransferase WbsX 7 353 4.0E-138 T 28-03-2018 IPR032719 Glycosyltransferase WbsX MKLM6_RS17655 d8f721de6a897af1244cbf97a7417caf 72 Pfam PF11390 NADH-dependant formate dehydrogenase delta subunit FdsD 5 65 7.1E-28 T 28-03-2018 IPR021074 Formate dehydrogenase, delta subunit MKLM6_RS13725 c75fbb56c32a26701af1541c01a7ac72 454 Pfam PF02120 Flagellar hook-length control protein FliK 317 399 8.3E-22 T 28-03-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal MKLM6_RS11865 a1d0c3b47d36ad013ae659a9787c305d 269 Pfam PF04536 TPM domain 25 146 9.9E-38 T 28-03-2018 IPR007621 TPM domain MKLM6_RS04545 b1357c39338c1137a7db994c60d59802 141 Pfam PF14485 Domain of unknown function (DUF4431) 94 137 1.5E-13 T 28-03-2018 IPR027826 Domain of unknown function DUF4431 MKLM6_RS09665 eb28a6c4b8eadadbba0ad6e01c235e82 141 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 26 118 4.5E-9 T 28-03-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III MKLM6_RS06010 ef7a8d02048131d26b4acadedd2d282c 352 Gene3D G3DSA:2.40.160.10 27 351 6.8E-19 T 28-03-2018 MKLM6_RS06010 ef7a8d02048131d26b4acadedd2d282c 352 SUPERFAMILY SSF56935 63 340 2.62E-12 T 28-03-2018 MKLM6_RS06220 274b320ad59bdd9a914bf201544aa593 144 Pfam PF10097 Predicted membrane protein (DUF2335) 39 95 8.1E-11 T 28-03-2018 IPR019284 Xylella phage Xfas53, Orf42 MKLM6_RS07350 8034f144da0f8b66d032cb2cf05888bc 190 Pfam PF11075 Protein of unknown function VcgC/VcgE (DUF2780) 56 189 1.2E-38 T 28-03-2018 IPR021302 Protein of unknown function DUF2780, VcgC/VcgE MKLM6_RS05495 2fc2ed4d940c55fa186edb862b3bb856 66 Pfam PF13619 KTSC domain 7 62 1.8E-15 T 28-03-2018 IPR025309 KTSC domain MKLM6_RS10495 bcb58d52d1a49200a496671f401802d0 502 Pfam PF13372 Alginate export 64 465 6.5E-85 T 28-03-2018 IPR025388 Alginate export domain MKLM6_RS21690 acf288a50ffd2ac7f82d4dc0b78824d7 269 Pfam PF01925 Sulfite exporter TauE/SafE 7 265 1.0E-47 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MKLM6_RS08420 af865feadfc835f6802253f5094b3f09 137 Pfam PF02472 Biopolymer transport protein ExbD/TolR 15 134 5.0E-28 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 MKLM6_RS14785 3481310fc5c722e1b8109aeffc96682c 97 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 3 89 4.4E-7 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MKLM6_RS15550 4db6396c63e45219bd47248a1715be75 97 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 90 1.1E-7 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MKLM6_RS11390 1a3e432c72efa0fcb2b62f0600e912aa 304 Pfam PF03547 Membrane transport protein 163 300 1.1E-14 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 MKLM6_RS11390 1a3e432c72efa0fcb2b62f0600e912aa 304 Pfam PF03547 Membrane transport protein 11 159 3.5E-9 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085