locus-tag	class	description
ACJ67_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ACJ67_RS00165	COG0625	glutathione transferase activity
ACJ67_RS00170	COG1028	Short-chain dehydrogenase reductase Sdr
ACJ67_RS00180	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ACJ67_RS00185	COG0732	type I restriction modification DNA specificity domain
ACJ67_RS00200	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ACJ67_RS00210	COG5001	Diguanylate cyclase
ACJ67_RS00210	COG3300	MHYT domain
ACJ67_RS00215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACJ67_RS00220	COG0714	Associated with various cellular activities
ACJ67_RS00255	COG1335	isochorismatase
ACJ67_RS00265	COG0583	DNA-binding transcription factor activity
ACJ67_RS00280	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACJ67_RS00285	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACJ67_RS00290	COG1758	RNA polymerase activity
ACJ67_RS00295	COG0194	GDP metabolic process
ACJ67_RS00305	COG1305	Transglutaminase-like
ACJ67_RS00315	COG2308	Evidence 4 Homologs of previously reported genes of
ACJ67_RS00320	COG1561	YicC-like family, N-terminal region
ACJ67_RS00325	COG0515	serine threonine protein kinase
ACJ67_RS00325	COG3064	Membrane
ACJ67_RS00325	COG4991	sh3 domain protein
ACJ67_RS00330	COG0631	protein serine/threonine phosphatase activity
ACJ67_RS00335	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ACJ67_RS00340	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ACJ67_RS00350	COG0514	ATP-dependent DNA helicase (RecQ)
ACJ67_RS00370	COG4181	ATPase activity
ACJ67_RS00375	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ACJ67_RS00380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACJ67_RS00390	COG0165	Argininosuccinate lyase
ACJ67_RS00395	COG3275	phosphorelay sensor kinase activity
ACJ67_RS00410	COG0181	hydroxymethylbilane synthase activity
ACJ67_RS00460	COG1368	sulfuric ester hydrolase activity
ACJ67_RS00495	COG1846	Transcriptional regulator
ACJ67_RS00500	COG0753	catalase activity
ACJ67_RS00505	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACJ67_RS00510	COG3781	membrane
ACJ67_RS00525	COG0189	ligase activity
ACJ67_RS00535	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACJ67_RS00540	COG0321	lipoyl(octanoyl) transferase activity
ACJ67_RS00545	COG2921	Belongs to the UPF0250 family
ACJ67_RS00550	COG1686	Belongs to the peptidase S11 family
ACJ67_RS00560	COG0772	Belongs to the SEDS family
ACJ67_RS00565	COG0768	penicillin binding
ACJ67_RS00570	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ACJ67_RS00580	COG1077	Cell shape determining protein MreB Mrl
ACJ67_RS00585	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACJ67_RS00590	COG0154	amidase activity
ACJ67_RS00595	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACJ67_RS00605	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ACJ67_RS00620	COG4681	YaeQ
ACJ67_RS00650	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ACJ67_RS00655	COG0494	nUDIX hydrolase
ACJ67_RS00660	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ACJ67_RS00665	COG0788	formyltetrahydrofolate deformylase activity
ACJ67_RS00720	COG0606	chelatase, subunit chli
ACJ67_RS00790	COG1285	pathogenesis
ACJ67_RS00800	COG1815	bacterial-type flagellum-dependent cell motility
ACJ67_RS00850	COG0659	secondary active sulfate transmembrane transporter activity
ACJ67_RS00880	COG0347	Belongs to the P(II) protein family
ACJ67_RS00885	COG0004	ammonium transporteR
ACJ67_RS00890	COG1132	(ABC) transporter
ACJ67_RS00945	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ACJ67_RS00950	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ACJ67_RS00955	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ACJ67_RS00960	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ACJ67_RS00980	COG3706	GGDEF domain
ACJ67_RS00985	COG4796	Type ii and iii secretion system protein
ACJ67_RS00995	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACJ67_RS01000	COG1459	type II secretion system
ACJ67_RS01025	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ACJ67_RS01040	COG0525	valine-tRNA ligase activity
ACJ67_RS01070	COG1305	Transglutaminase-like
ACJ67_RS01080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACJ67_RS01085	COG0500	methyltransferase
ACJ67_RS01100	COG0339	signal peptide processing
ACJ67_RS01105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACJ67_RS01120	COG1660	Displays ATPase and GTPase activities
ACJ67_RS01125	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ACJ67_RS01135	COG3145	DNA-N1-methyladenine dioxygenase activity
ACJ67_RS01170	COG1538	Outer membrane efflux protein
ACJ67_RS01200	COG1346	cytolysis
ACJ67_RS01385	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACJ67_RS01395	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ACJ67_RS01410	COG3263	regulation of cellular component size
ACJ67_RS01435	COG3220	belongs to the UPF0276 family
ACJ67_RS01445	COG1028	Short-chain dehydrogenase reductase Sdr
ACJ67_RS01455	COG3781	membrane
ACJ67_RS01475	COG2197	response regulator
ACJ67_RS01480	COG4191	Histidine kinase
ACJ67_RS01495	COG1451	nucleotide metabolic process
ACJ67_RS01500	COG2264	protein methyltransferase activity
ACJ67_RS01545	COG3453	Protein conserved in bacteria
ACJ67_RS01545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACJ67_RS01565	COG1294	oxidase, subunit
ACJ67_RS01590	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ACJ67_RS01625	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
ACJ67_RS01630	COG5001	Diguanylate cyclase
ACJ67_RS01635	COG0835	chemotaxis
ACJ67_RS01650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACJ67_RS01655	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ACJ67_RS01660	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ACJ67_RS01670	COG2808	Putative FMN-binding domain
ACJ67_RS01680	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ACJ67_RS01685	COG1492	cobalamin metabolic process
ACJ67_RS01690	COG2501	S4 domain
ACJ67_RS01705	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ACJ67_RS01710	COG0778	Nitroreductase
ACJ67_RS01715	COG1797	cobyrinic acid a,c-diamide synthase activity
ACJ67_RS01730	COG4206	TonB-dependent receptor
ACJ67_RS01755	COG3706	GGDEF domain
ACJ67_RS01770	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ACJ67_RS01785	COG2922	Belongs to the Smg family
ACJ67_RS01790	COG0758	DNA mediated transformation
ACJ67_RS01800	COG0242	peptide deformylase activity
ACJ67_RS01805	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ACJ67_RS01810	COG0501	Belongs to the peptidase M48B family
ACJ67_RS01825	COG5000	phosphorelay sensor kinase activity
ACJ67_RS01830	COG2204	response regulator
ACJ67_RS01860	COG0795	lipopolysaccharide-transporting ATPase activity
ACJ67_RS01865	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACJ67_RS01885	COG2807	transmembrane transport
ACJ67_RS01900	COG2169	Transcriptional regulator
ACJ67_RS01900	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACJ67_RS01925	COG0835	chemotaxis
ACJ67_RS01975	COG4302	ethanolamine ammonia-lyase activity
ACJ67_RS02000	COG0439	Biotin carboxylase
ACJ67_RS02015	COG3842	ATPase activity
ACJ67_RS02045	COG3237	CsbD-like
ACJ67_RS02065	COG2823	Periplasmic or secreted lipoprotein
ACJ67_RS02075	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACJ67_RS02120	COG3621	Patatin-like phospholipase
ACJ67_RS02155	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ACJ67_RS02200	COG1285	pathogenesis
ACJ67_RS02270	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACJ67_RS02275	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ACJ67_RS02285	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ACJ67_RS02290	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ACJ67_RS02305	COG0037	tRNA processing
ACJ67_RS02325	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ACJ67_RS02330	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ACJ67_RS02340	COG1333	cytochrome c biogenesis protein
ACJ67_RS02345	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACJ67_RS02355	COG1127	ABC transporter
ACJ67_RS02360	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACJ67_RS02365	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACJ67_RS02370	COG2854	intermembrane phospholipid transfer
ACJ67_RS02380	COG1131	(ABC) transporter
ACJ67_RS02385	COG0842	Transport permease protein
ACJ67_RS02395	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ACJ67_RS02400	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACJ67_RS02405	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ACJ67_RS02410	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ACJ67_RS02415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACJ67_RS02425	COG0131	Imidazoleglycerol-phosphate dehydratase
ACJ67_RS02430	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ACJ67_RS02435	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ACJ67_RS02440	COG0107	imidazoleglycerol-phosphate synthase activity
ACJ67_RS02445	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACJ67_RS02450	COG0140	phosphoribosyl-ATP diphosphatase activity
ACJ67_RS02455	COG0537	adenosine 5'-monophosphoramidase activity
ACJ67_RS02460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACJ67_RS02465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACJ67_RS02485	COG0723	plastoquinol--plastocyanin reductase activity
ACJ67_RS02490	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ACJ67_RS02495	COG2857	Cytochrome c1
ACJ67_RS02500	COG0625	glutathione transferase activity
ACJ67_RS02505	COG2969	positive regulation of protein catabolic process
ACJ67_RS02530	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACJ67_RS02540	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACJ67_RS02550	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ACJ67_RS02555	COG0081	regulation of translation
ACJ67_RS02560	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ACJ67_RS02565	COG0222	ribosome binding
ACJ67_RS02570	COG0085	RNA polymerase activity
ACJ67_RS02575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACJ67_RS02580	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ACJ67_RS02585	COG0049	tRNA binding
ACJ67_RS02590	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ACJ67_RS02595	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACJ67_RS02600	COG0051	transcription antitermination factor activity, RNA binding
ACJ67_RS02605	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ACJ67_RS02610	COG0088	Forms part of the polypeptide exit tunnel
ACJ67_RS02615	COG0089	rRNA binding
ACJ67_RS02620	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACJ67_RS02625	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ACJ67_RS02630	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ACJ67_RS02635	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ACJ67_RS02640	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ACJ67_RS02645	COG0255	Belongs to the universal ribosomal protein uL29 family
ACJ67_RS02650	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ACJ67_RS02655	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ACJ67_RS02660	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ACJ67_RS02665	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACJ67_RS02670	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ACJ67_RS02675	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ACJ67_RS02680	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ACJ67_RS02685	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ACJ67_RS02690	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ACJ67_RS02695	COG1841	ribosomal large subunit assembly
ACJ67_RS02700	COG0200	Binds to the 23S rRNA
ACJ67_RS02705	COG0201	protein transport
ACJ67_RS02710	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ACJ67_RS02715	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ACJ67_RS02720	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ACJ67_RS02725	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACJ67_RS02730	COG0202	RNA polymerase activity
ACJ67_RS02735	COG0203	ribosomal protein L17
ACJ67_RS02745	COG2239	Acts as a magnesium transporter
ACJ67_RS02750	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ACJ67_RS02750	COG3264	Mechanosensitive ion channel
ACJ67_RS02755	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ACJ67_RS02760	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ACJ67_RS02765	COG0756	dUTP diphosphatase activity
ACJ67_RS02770	COG4772	TonB-dependent receptor
ACJ67_RS02785	COG2003	Belongs to the UPF0758 family
ACJ67_RS02800	COG1966	Carbon starvation protein
ACJ67_RS02815	COG0129	dihydroxy-acid dehydratase activity
ACJ67_RS02820	COG0676	glucose-6-phosphate 1-epimerase activity
ACJ67_RS02825	COG4654	Cytochrome c, class I
ACJ67_RS02830	COG0733	neurotransmitter:sodium symporter activity
ACJ67_RS02835	COG1115	amino acid carrier protein
ACJ67_RS02840	COG1362	aminopeptidase activity
ACJ67_RS02845	COG0408	coproporphyrinogen oxidase activity
ACJ67_RS02850	COG0151	Belongs to the GarS family
ACJ67_RS02855	COG0138	bifunctional purine biosynthesis protein purh
ACJ67_RS02890	COG0477	Major facilitator Superfamily
ACJ67_RS02895	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ACJ67_RS02910	COG1058	Belongs to the CinA family
ACJ67_RS02910	COG1546	Belongs to the CinA family
ACJ67_RS02930	COG1611	Belongs to the LOG family
ACJ67_RS02940	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ACJ67_RS02955	COG0210	DNA helicase
ACJ67_RS02960	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ACJ67_RS02965	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACJ67_RS02970	COG1459	type II secretion system
ACJ67_RS02975	COG4969	Belongs to the N-Me-Phe pilin family
ACJ67_RS03030	COG3267	Type II secretory pathway component ExeA
ACJ67_RS03030	COG3409	Peptidoglycan-binding domain 1 protein
ACJ67_RS03045	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACJ67_RS03050	COG0156	8-amino-7-oxononanoate synthase activity
ACJ67_RS03055	COG0596	Alpha beta hydrolase
ACJ67_RS03065	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ACJ67_RS03075	COG0438	transferase activity, transferring glycosyl groups
ACJ67_RS03085	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACJ67_RS03090	COG0443	Heat shock 70 kDa protein
ACJ67_RS03095	COG0484	heat shock protein binding
ACJ67_RS03100	COG1192	Involved in chromosome partitioning
ACJ67_RS03105	COG0598	Magnesium transport protein CorA
ACJ67_RS03110	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ACJ67_RS03120	COG1469	GTP cyclohydrolase I activity
ACJ67_RS03125	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ACJ67_RS03130	COG0142	geranyltranstransferase activity
ACJ67_RS03155	COG3391	amine dehydrogenase activity
ACJ67_RS03160	COG0494	nUDIX hydrolase
ACJ67_RS03165	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACJ67_RS03170	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACJ67_RS03175	COG0126	phosphoglycerate kinase activity
ACJ67_RS03180	COG4251	negative regulation of phosphorylation
ACJ67_RS03180	COG3706	GGDEF domain
ACJ67_RS03180	COG2203	Gaf domain
ACJ67_RS03180	COG5001	Diguanylate cyclase
ACJ67_RS03185	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACJ67_RS03190	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ACJ67_RS03200	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ACJ67_RS03215	COG0739	heme binding
ACJ67_RS03220	COG0653	protein targeting
ACJ67_RS03240	COG3220	belongs to the UPF0276 family
ACJ67_RS03260	COG0628	permease
ACJ67_RS03270	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACJ67_RS03275	COG2878	Part of a membrane complex involved in electron transport
ACJ67_RS03280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACJ67_RS03285	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ACJ67_RS03320	COG0542	response to heat
ACJ67_RS03325	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ACJ67_RS03330	COG4536	flavin adenine dinucleotide binding
ACJ67_RS03335	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACJ67_RS03340	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACJ67_RS03345	COG1862	Preprotein translocase
ACJ67_RS03350	COG0343	queuine tRNA-ribosyltransferase activity
ACJ67_RS03355	COG1183	phosphatidylcholine synthase activity
ACJ67_RS03360	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACJ67_RS03365	COG0697	spore germination
ACJ67_RS03385	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACJ67_RS03415	COG0513	Belongs to the DEAD box helicase family
ACJ67_RS03420	COG1671	Belongs to the UPF0178 family
ACJ67_RS03450	COG1846	Transcriptional regulator
ACJ67_RS03465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACJ67_RS03475	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ACJ67_RS03480	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ACJ67_RS03485	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACJ67_RS03490	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ACJ67_RS03495	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ACJ67_RS03500	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ACJ67_RS03510	COG0268	Binds directly to 16S ribosomal RNA
ACJ67_RS03520	COG0196	riboflavin kinase activity
ACJ67_RS03525	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACJ67_RS03530	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ACJ67_RS03545	COG2354	Protein conserved in bacteria
ACJ67_RS03605	COG0542	response to heat
ACJ67_RS03615	COG0432	Pfam Uncharacterised protein family UPF0047
ACJ67_RS03625	COG4942	peptidase
ACJ67_RS03630	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ACJ67_RS03635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACJ67_RS03645	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ACJ67_RS03650	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ACJ67_RS03660	COG0545	Peptidyl-prolyl cis-trans isomerase
ACJ67_RS03665	COG0459	protein refolding
ACJ67_RS03670	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ACJ67_RS03695	COG1335	isochorismatase
ACJ67_RS03715	COG1802	Transcriptional regulator
ACJ67_RS03720	COG2203	Gaf domain
ACJ67_RS03720	COG3706	GGDEF domain
ACJ67_RS03720	COG4251	negative regulation of phosphorylation
ACJ67_RS03720	COG5001	Diguanylate cyclase
ACJ67_RS03725	COG0840	transmembrane signaling receptor activity
ACJ67_RS03725	COG5278	phosphoserine phosphatase activity
ACJ67_RS03740	COG2198	Histidine kinase
ACJ67_RS03740	COG0643	Histidine kinase
ACJ67_RS03745	COG0840	transmembrane signaling receptor activity
ACJ67_RS03750	COG0835	chemotaxis
ACJ67_RS03760	COG0840	transmembrane signaling receptor activity
ACJ67_RS03775	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ACJ67_RS03780	COG2201	protein-glutamate methylesterase activity
ACJ67_RS03790	COG0243	molybdopterin cofactor binding
ACJ67_RS03800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACJ67_RS03805	COG5002	protein histidine kinase activity
ACJ67_RS03805	COG0784	Response regulator, receiver
ACJ67_RS03805	COG2205	protein histidine kinase activity
ACJ67_RS03810	COG0784	Response regulator, receiver
ACJ67_RS03815	COG3437	response regulator, receiver
ACJ67_RS03825	COG5001	Diguanylate cyclase
ACJ67_RS03825	COG3300	MHYT domain
ACJ67_RS03830	COG3706	GGDEF domain
ACJ67_RS03830	COG2203	Gaf domain
ACJ67_RS03830	COG5001	Diguanylate cyclase
ACJ67_RS03830	COG4251	negative regulation of phosphorylation
ACJ67_RS03835	COG3300	MHYT domain
ACJ67_RS03835	COG5001	Diguanylate cyclase
ACJ67_RS03915	COG1459	type II secretion system
ACJ67_RS04000	COG0583	DNA-binding transcription factor activity
ACJ67_RS04005	COG1028	Short-chain dehydrogenase reductase Sdr
ACJ67_RS04040	COG0667	Aldo Keto reductase
ACJ67_RS04075	COG0668	transmembrane transport
ACJ67_RS04085	COG2197	response regulator
ACJ67_RS04100	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACJ67_RS04110	COG1028	Short-chain dehydrogenase reductase Sdr
ACJ67_RS04140	COG2823	Periplasmic or secreted lipoprotein
ACJ67_RS04155	COG0596	Alpha beta hydrolase
ACJ67_RS04160	COG3550	peptidyl-serine autophosphorylation
ACJ67_RS04165	COG1396	sequence-specific DNA binding
ACJ67_RS04180	COG1595	DNA-templated transcription, initiation
ACJ67_RS04190	COG0429	hydrolase of the alpha beta-hydrolase fold
ACJ67_RS04245	COG2199	diguanylate cyclase activity
ACJ67_RS04245	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ACJ67_RS04250	COG0012	GTP binding
ACJ67_RS04260	COG0193	aminoacyl-tRNA hydrolase activity
ACJ67_RS04265	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ACJ67_RS04270	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACJ67_RS04280	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ACJ67_RS04290	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ACJ67_RS04320	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ACJ67_RS04325	COG3706	GGDEF domain
ACJ67_RS04340	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACJ67_RS04350	COG2226	methyltransferase
ACJ67_RS04365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACJ67_RS04380	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ACJ67_RS04435	COG0829	nickel cation binding
ACJ67_RS04440	COG0831	urea catabolic process
ACJ67_RS04445	COG0832	Belongs to the urease beta subunit family
ACJ67_RS04450	COG0804	urea catabolic process
ACJ67_RS04455	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ACJ67_RS04460	COG0830	nickel cation binding
ACJ67_RS04465	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ACJ67_RS04480	COG0784	Response regulator, receiver
ACJ67_RS04480	COG2205	protein histidine kinase activity
ACJ67_RS04480	COG2198	Histidine kinase
ACJ67_RS04480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACJ67_RS04495	COG2814	Major facilitator Superfamily
ACJ67_RS04515	COG0583	DNA-binding transcription factor activity
ACJ67_RS04525	COG2177	Part of the ABC transporter FtsEX involved in
ACJ67_RS04530	COG2884	Cell division ATP-binding protein ftsE
ACJ67_RS04540	COG0612	Peptidase, M16
ACJ67_RS04545	COG0612	Peptidase, M16
ACJ67_RS04555	COG0742	ribosomal rna small subunit methyltransferase
ACJ67_RS04560	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ACJ67_RS04565	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACJ67_RS04590	COG3237	CsbD-like
ACJ67_RS04600	COG1136	(ABC) transporter
ACJ67_RS04615	COG0848	biopolymer transport protein
ACJ67_RS04620	COG1132	(ABC) transporter
ACJ67_RS04625	COG1663	tetraacyldisaccharide 4'-kinase activity
ACJ67_RS04630	COG2835	tetraacyldisaccharide 4'-kinase activity
ACJ67_RS04635	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ACJ67_RS04665	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ACJ67_RS04670	COG0045	succinate-CoA ligase (ADP-forming) activity
ACJ67_RS04680	COG0560	Phosphoserine phosphatase
ACJ67_RS04685	COG1278	Cold shock
ACJ67_RS04690	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ACJ67_RS04695	COG0459	protein refolding
ACJ67_RS04705	COG0583	DNA-binding transcription factor activity
ACJ67_RS04715	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACJ67_RS04720	COG3002	Belongs to the UPF0753 family
ACJ67_RS04725	COG2199	diguanylate cyclase activity
ACJ67_RS04725	COG2200	EAL domain
ACJ67_RS04725	COG3287	FIST C domain
ACJ67_RS04730	COG2833	Protein of unknown function (DUF455)
ACJ67_RS04735	COG0642	Histidine kinase
ACJ67_RS04740	COG0745	RESPONSE REGULATOR receiver
ACJ67_RS04765	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACJ67_RS04780	COG0047	phosphoribosylformylglycinamidine synthase activity
ACJ67_RS04780	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACJ67_RS04790	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ACJ67_RS04800	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACJ67_RS04810	COG2350	Protein conserved in bacteria
ACJ67_RS04815	COG2917	probably involved in intracellular septation
ACJ67_RS04820	COG0613	PHP domain protein
ACJ67_RS04825	COG0009	L-threonylcarbamoyladenylate synthase
ACJ67_RS04830	COG1994	Peptidase M50
ACJ67_RS04840	COG4535	Mg2 and Co2 transporter CorC
ACJ67_RS04850	COG1970	mechanosensitive ion channel activity
ACJ67_RS04855	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ACJ67_RS04860	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ACJ67_RS04870	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ACJ67_RS04875	COG0415	Belongs to the DNA photolyase family
ACJ67_RS04885	COG0312	modulator of DNA gyrase
ACJ67_RS04890	COG3028	Belongs to the UPF0307 family
ACJ67_RS04895	COG0425	Belongs to the sulfur carrier protein TusA family
ACJ67_RS04910	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACJ67_RS04925	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ACJ67_RS04945	COG2137	regulation of response to DNA damage stimulus
ACJ67_RS04950	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ACJ67_RS04970	COG0142	geranyltranstransferase activity
ACJ67_RS04985	COG0237	dephospho-CoA kinase activity
ACJ67_RS04990	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ACJ67_RS05000	COG4628	conserved protein (DUF2132)
ACJ67_RS05005	COG0494	nUDIX hydrolase
ACJ67_RS05015	COG0424	maF-like protein
ACJ67_RS05020	COG1530	ribonuclease E activity
ACJ67_RS05025	COG0762	integral membrane protein
ACJ67_RS05055	COG0540	Belongs to the ATCase OTCase family
ACJ67_RS05060	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ACJ67_RS05065	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ACJ67_RS05070	COG1678	Uncharacterized ACR, COG1678
ACJ67_RS05085	COG2321	neutral zinc metallopeptidase
ACJ67_RS05100	COG2951	lytic endotransglycosylase activity
ACJ67_RS05115	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ACJ67_RS05120	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ACJ67_RS05125	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ACJ67_RS05130	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ACJ67_RS05135	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ACJ67_RS05140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACJ67_RS05140	COG0072	phenylalanine-tRNA ligase activity
ACJ67_RS05145	COG0776	regulation of translation
ACJ67_RS05170	COG5001	Diguanylate cyclase
ACJ67_RS05170	COG5002	protein histidine kinase activity
ACJ67_RS05180	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACJ67_RS05195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACJ67_RS05200	COG1393	Belongs to the ArsC family
ACJ67_RS05210	COG2171	N-acyltransferase activity
ACJ67_RS05215	COG4783	chaperone-mediated protein folding
ACJ67_RS05220	COG3158	transport of potassium into the cell
ACJ67_RS05225	COG1570	exodeoxyribonuclease VII activity
ACJ67_RS05235	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ACJ67_RS05290	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACJ67_RS05305	COG1376	ErfK ybiS ycfS ynhG family protein
ACJ67_RS05315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACJ67_RS05330	COG1472	Belongs to the glycosyl hydrolase 3 family
ACJ67_RS05360	COG4555	ABC transporter
ACJ67_RS05365	COG1668	transmembrane transport
ACJ67_RS05375	COG1131	(ABC) transporter
ACJ67_RS05380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACJ67_RS05405	COG2226	methyltransferase
ACJ67_RS05410	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACJ67_RS05445	COG4964	Belongs to the GSP D family
ACJ67_RS05460	COG0489	protein tyrosine kinase activity
ACJ67_RS05500	COG0590	tRNA wobble adenosine to inosine editing
ACJ67_RS05510	COG0583	DNA-binding transcription factor activity
ACJ67_RS05515	COG1741	Belongs to the pirin family
ACJ67_RS05525	COG2353	YceI-like domain
ACJ67_RS05530	COG1902	pentaerythritol trinitrate reductase activity
ACJ67_RS05535	COG0149	triose-phosphate isomerase activity
ACJ67_RS05540	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACJ67_RS05550	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACJ67_RS05555	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACJ67_RS05560	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACJ67_RS05565	COG0649	NAD binding
ACJ67_RS05570	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ACJ67_RS05580	COG1034	ATP synthesis coupled electron transport
ACJ67_RS05585	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACJ67_RS05590	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACJ67_RS05600	COG0713	ATP synthesis coupled electron transport
ACJ67_RS05615	COG1007	ATP synthesis coupled electron transport
ACJ67_RS05625	COG0671	phosphoesterase, PA-phosphatase related
ACJ67_RS05640	COG1278	Cold shock
ACJ67_RS05645	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ACJ67_RS05655	COG1028	Short-chain dehydrogenase reductase Sdr
ACJ67_RS05670	COG0714	Associated with various cellular activities
ACJ67_RS05700	COG1408	metallophosphoesterase
ACJ67_RS05710	COG0438	transferase activity, transferring glycosyl groups
ACJ67_RS05720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACJ67_RS05725	COG0581	inorganic phosphate transmembrane transporter activity
ACJ67_RS05730	COG0573	inorganic phosphate transmembrane transporter activity
ACJ67_RS05735	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ACJ67_RS05740	COG0306	phosphate transporter
ACJ67_RS05745	COG1392	Phosphate transport regulator
ACJ67_RS05750	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ACJ67_RS05755	COG3012	SEC-C Motif Domain Protein
ACJ67_RS05765	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ACJ67_RS05770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACJ67_RS05775	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ACJ67_RS05780	COG3706	GGDEF domain
ACJ67_RS05785	COG2376	Dihydroxyacetone kinase
ACJ67_RS05790	COG1461	Dihydroxyacetone kinase
ACJ67_RS05830	COG0052	Belongs to the universal ribosomal protein uS2 family
ACJ67_RS05835	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ACJ67_RS05840	COG0528	UMP kinase activity
ACJ67_RS05845	COG0233	cytoplasmic translational termination
ACJ67_RS05850	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACJ67_RS05855	COG0575	Belongs to the CDS family
ACJ67_RS05860	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ACJ67_RS05880	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACJ67_RS05885	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACJ67_RS05890	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACJ67_RS05895	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACJ67_RS05900	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACJ67_RS05905	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ACJ67_RS05910	COG2895	sulfate adenylyltransferase (ATP) activity
ACJ67_RS05915	COG0175	sulfate reduction
ACJ67_RS05920	COG0175	sulfate reduction
ACJ67_RS05935	COG0730	response to heat
ACJ67_RS05950	COG0433	COG0433 Predicted ATPase
ACJ67_RS05955	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ACJ67_RS05960	COG1739	Uncharacterized protein family UPF0029
ACJ67_RS05990	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ACJ67_RS05995	COG0314	molybdopterin synthase activity
ACJ67_RS06000	COG1067	ATP-dependent peptidase activity
ACJ67_RS06005	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ACJ67_RS06020	COG0360	Binds together with S18 to 16S ribosomal RNA
ACJ67_RS06025	COG2965	DNA replication, synthesis of RNA primer
ACJ67_RS06030	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ACJ67_RS06035	COG0359	binds to the 23S rRNA
ACJ67_RS06040	COG0305	Participates in initiation and elongation during chromosome replication
ACJ67_RS06045	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACJ67_RS06060	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ACJ67_RS06070	COG1562	ergosterol biosynthetic process
ACJ67_RS06080	COG0242	peptide deformylase activity
ACJ67_RS06120	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ACJ67_RS06125	COG0024	Methionine aminopeptidase
ACJ67_RS06140	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACJ67_RS06145	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ACJ67_RS06155	COG0717	Belongs to the dCTP deaminase family
ACJ67_RS06160	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACJ67_RS06165	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ACJ67_RS06170	COG0363	glucosamine-6-phosphate deaminase activity
ACJ67_RS06180	COG0489	protein tyrosine kinase activity
ACJ67_RS06185	COG0438	transferase activity, transferring glycosyl groups
ACJ67_RS06190	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ACJ67_RS06215	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ACJ67_RS06235	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACJ67_RS06235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACJ67_RS06240	COG2217	Heavy metal translocating P-type atpase
ACJ67_RS06250	COG3278	Belongs to the heme-copper respiratory oxidase family
ACJ67_RS06270	COG0348	domain, Protein
ACJ67_RS06285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACJ67_RS06290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACJ67_RS06300	COG1793	dna ligase
ACJ67_RS06310	COG1643	Atp-dependent helicase
ACJ67_RS06350	COG2862	Uncharacterized protein family, UPF0114
ACJ67_RS06355	COG0523	cobalamin synthesis protein
ACJ67_RS06375	COG3549	Plasmid maintenance system killer
ACJ67_RS06405	COG0475	glutathione-regulated potassium exporter activity
ACJ67_RS06410	COG3706	GGDEF domain
ACJ67_RS06420	COG3008	intermembrane lipid transfer
ACJ67_RS06420	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACJ67_RS06425	COG2995	paraquat-inducible protein a
ACJ67_RS06445	COG1294	oxidase, subunit
ACJ67_RS06450	COG1271	oxidase subunit
ACJ67_RS06470	COG0436	Aminotransferase
ACJ67_RS06475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACJ67_RS06480	COG0556	nucleotide-excision repair
ACJ67_RS06495	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ACJ67_RS06510	COG5002	protein histidine kinase activity
ACJ67_RS06510	COG3850	Histidine kinase
ACJ67_RS06525	COG0488	(ABC) transporter
ACJ67_RS06530	COG0778	Nitroreductase
ACJ67_RS06545	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACJ67_RS06545	COG0519	Catalyzes the synthesis of GMP from XMP
ACJ67_RS06560	COG2914	Belongs to the UPF0125 (RnfH) family
ACJ67_RS06565	COG2867	negative regulation of translational initiation
ACJ67_RS06570	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ACJ67_RS06575	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACJ67_RS06575	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACJ67_RS06580	COG0504	CTP synthase activity
ACJ67_RS06585	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ACJ67_RS06590	COG0148	phosphopyruvate hydratase activity
ACJ67_RS06595	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ACJ67_RS06640	COG0714	Associated with various cellular activities
ACJ67_RS06645	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACJ67_RS06670	COG0436	Aminotransferase
ACJ67_RS06685	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ACJ67_RS06705	COG1162	GTPase activity
ACJ67_RS06715	COG0501	Belongs to the peptidase M48B family
ACJ67_RS06720	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ACJ67_RS06725	COG0297	glycogen (starch) synthase activity
ACJ67_RS06730	COG1530	ribonuclease E activity
ACJ67_RS06740	COG0546	phosphoglycolate phosphatase activity
ACJ67_RS06755	COG1160	GTP binding
ACJ67_RS06785	COG0124	histidyl-tRNA synthetase
ACJ67_RS06790	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ACJ67_RS06805	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ACJ67_RS06810	COG0105	UTP biosynthetic process
ACJ67_RS06820	COG1229	Formylmethanofuran dehydrogenase subunit A
ACJ67_RS06825	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
ACJ67_RS06835	COG1054	Belongs to the UPF0176 family
ACJ67_RS06985	COG2133	pyrroloquinoline quinone binding
ACJ67_RS06990	COG1742	UPF0060 membrane protein
ACJ67_RS06995	COG4774	siderophore transport
ACJ67_RS07005	COG1595	DNA-templated transcription, initiation
ACJ67_RS07015	COG0564	pseudouridine synthase activity
ACJ67_RS07040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACJ67_RS07050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACJ67_RS07055	COG1923	regulation of RNA biosynthetic process
ACJ67_RS07060	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACJ67_RS07065	COG0330	HflC and HflK could
ACJ67_RS07070	COG0330	HflC and HflK could
ACJ67_RS07080	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ACJ67_RS07085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACJ67_RS07110	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ACJ67_RS07110	COG2885	chlorophyll binding
ACJ67_RS07115	COG0402	S-adenosylhomocysteine deaminase activity
ACJ67_RS07120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACJ67_RS07130	COG1716	ATPase activity
ACJ67_RS07130	COG5001	Diguanylate cyclase
ACJ67_RS07135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ACJ67_RS07155	COG3851	Histidine kinase
ACJ67_RS07160	COG2197	response regulator
ACJ67_RS07165	COG0166	Belongs to the GPI family
ACJ67_RS07170	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ACJ67_RS07175	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ACJ67_RS07190	COG1940	carbohydrate kinase activity
ACJ67_RS07200	COG0802	atpase or kinase
ACJ67_RS07205	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACJ67_RS07220	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACJ67_RS07225	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACJ67_RS07240	COG1733	regulation of RNA biosynthetic process
ACJ67_RS07265	COG0424	maF-like protein
ACJ67_RS07270	COG5016	pyruvate
ACJ67_RS07270	COG0511	ligase activity, forming carbon-carbon bonds
ACJ67_RS07275	COG0439	Biotin carboxylase
ACJ67_RS07285	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ACJ67_RS07290	COG0416	fatty acid biosynthetic process
ACJ67_RS07295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACJ67_RS07310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACJ67_RS07315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACJ67_RS07335	COG0825	malonyl-CoA metabolic process
ACJ67_RS07340	COG0037	tRNA processing
ACJ67_RS07350	COG2204	response regulator
ACJ67_RS07355	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ACJ67_RS07365	COG0513	Belongs to the DEAD box helicase family
ACJ67_RS07370	COG0513	Belongs to the DEAD box helicase family
ACJ67_RS07375	COG1217	gtp-binding protein TYPA
ACJ67_RS07390	COG2326	polyphosphate kinase activity
ACJ67_RS07400	COG2197	response regulator
ACJ67_RS07415	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ACJ67_RS07430	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ACJ67_RS07445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACJ67_RS07480	COG0251	oxidation-reduction process
ACJ67_RS07485	COG0544	peptidyl-prolyl cis-trans isomerase activity
ACJ67_RS07490	COG0740	serine-type endopeptidase activity
ACJ67_RS07495	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ACJ67_RS07500	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ACJ67_RS07520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACJ67_RS07525	COG1278	Cold shock
ACJ67_RS07550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACJ67_RS07555	COG0601	transmembrane transport
ACJ67_RS07565	COG0741	lytic transglycosylase activity
ACJ67_RS07565	COG1388	LysM domain
ACJ67_RS07570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACJ67_RS07575	COG2226	methyltransferase
ACJ67_RS07580	COG0328	RNA-DNA hybrid ribonuclease activity
ACJ67_RS07585	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACJ67_RS07610	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ACJ67_RS07615	COG1196	nuclear chromosome segregation
ACJ67_RS07625	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ACJ67_RS07690	COG0287	Prephenate dehydrogenase
ACJ67_RS07695	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACJ67_RS07705	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ACJ67_RS07715	COG0776	regulation of translation
ACJ67_RS07720	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ACJ67_RS07725	COG0284	orotidine-5'-phosphate decarboxylase activity
ACJ67_RS07730	COG1555	photosystem II stabilization
ACJ67_RS07740	COG1012	belongs to the aldehyde dehydrogenase family
ACJ67_RS07750	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ACJ67_RS07755	COG0745	RESPONSE REGULATOR receiver
ACJ67_RS07760	COG2201	protein-glutamate methylesterase activity
ACJ67_RS07765	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ACJ67_RS07775	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
ACJ67_RS07780	COG0840	transmembrane signaling receptor activity
ACJ67_RS07785	COG0840	transmembrane signaling receptor activity
ACJ67_RS07800	COG0840	transmembrane signaling receptor activity
ACJ67_RS07805	COG0840	transmembrane signaling receptor activity
ACJ67_RS07810	COG0840	transmembrane signaling receptor activity
ACJ67_RS07815	COG0840	transmembrane signaling receptor activity
ACJ67_RS07815	COG0840	transmembrane signaling receptor activity
ACJ67_RS07825	COG0835	chemotaxis
ACJ67_RS07830	COG2198	Histidine kinase
ACJ67_RS07830	COG0643	Histidine kinase
ACJ67_RS07835	COG0745	RESPONSE REGULATOR receiver
ACJ67_RS07855	COG2890	protein-(glutamine-N5) methyltransferase activity
ACJ67_RS07875	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACJ67_RS07895	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ACJ67_RS07900	COG1360	Flagellar Motor Protein
ACJ67_RS07910	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ACJ67_RS07915	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ACJ67_RS07925	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACJ67_RS07965	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACJ67_RS07970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACJ67_RS07970	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ACJ67_RS08010	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ACJ67_RS08040	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ACJ67_RS08065	COG0110	maltose O-acetyltransferase activity
ACJ67_RS08080	COG0438	transferase activity, transferring glycosyl groups
ACJ67_RS08130	COG1596	polysaccharide export
ACJ67_RS08145	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACJ67_RS08150	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ACJ67_RS08155	COG2154	pterin-4-alpha-carbinolamine dehydratase
ACJ67_RS08165	COG0189	ligase activity
ACJ67_RS08170	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
ACJ67_RS08180	COG0702	epimerase
ACJ67_RS08195	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ACJ67_RS08205	COG2814	Major facilitator Superfamily
ACJ67_RS08210	COG0535	radical SAM domain protein
ACJ67_RS08230	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACJ67_RS08265	COG1286	toxin biosynthetic process
ACJ67_RS08275	COG0285	dihydrofolate synthase activity
ACJ67_RS08280	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ACJ67_RS08285	COG0159	tryptophan synthase activity
ACJ67_RS08290	COG0133	tryptophan synthase activity
ACJ67_RS08295	COG0135	phosphoribosylanthranilate isomerase activity
ACJ67_RS08300	COG0101	tRNA pseudouridine synthase activity
ACJ67_RS08320	COG1666	GTP binding
ACJ67_RS08325	COG3123	guanosine phosphorylase activity
ACJ67_RS08330	COG0473	3-isopropylmalate dehydrogenase activity
ACJ67_RS08335	COG0066	3-isopropylmalate dehydratase activity
ACJ67_RS08340	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ACJ67_RS08350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACJ67_RS08355	COG0137	argininosuccinate synthase activity
ACJ67_RS08360	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACJ67_RS08365	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACJ67_RS08375	COG0579	oxidoreductase
ACJ67_RS08385	COG1132	(ABC) transporter
ACJ67_RS08390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACJ67_RS08395	COG0557	exoribonuclease II activity
ACJ67_RS08410	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ACJ67_RS08410	COG0321	lipoyl(octanoyl) transferase activity
ACJ67_RS08415	COG0084	hydrolase, TatD family'
ACJ67_RS08425	COG0470	DNA polymerase III
ACJ67_RS08430	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACJ67_RS08435	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACJ67_RS08465	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ACJ67_RS08470	COG0557	exoribonuclease II activity
ACJ67_RS08475	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ACJ67_RS08520	COG3850	Histidine kinase
ACJ67_RS08525	COG2197	response regulator
ACJ67_RS08545	COG0523	cobalamin synthesis protein
ACJ67_RS08550	COG0523	cobalamin synthesis protein
ACJ67_RS08590	COG3047	cAMP biosynthetic process
ACJ67_RS08605	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ACJ67_RS08635	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACJ67_RS08660	COG1028	Short-chain dehydrogenase reductase Sdr
ACJ67_RS08680	COG2089	acid synthase
ACJ67_RS08700	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACJ67_RS08715	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ACJ67_RS08730	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACJ67_RS08735	COG1086	Polysaccharide biosynthesis protein
ACJ67_RS08745	COG1132	(ABC) transporter
ACJ67_RS08760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACJ67_RS08770	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACJ67_RS08780	COG0488	(ABC) transporter
ACJ67_RS08795	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
ACJ67_RS08800	COG1815	bacterial-type flagellum-dependent cell motility
ACJ67_RS08805	COG1558	bacterial-type flagellum-dependent cell motility
ACJ67_RS08810	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ACJ67_RS08815	COG1749	Flagellar hook protein flgE
ACJ67_RS08820	COG4787	bacterial-type flagellum-dependent cell motility
ACJ67_RS08830	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ACJ67_RS08835	COG1706	bacterial-type flagellum-dependent cell motility
ACJ67_RS08850	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACJ67_RS08860	COG1987	bacterial-type flagellum assembly
ACJ67_RS08865	COG1338	Plays a role in the flagellum-specific transport system
ACJ67_RS08875	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACJ67_RS08880	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACJ67_RS08895	COG2882	bacterial-type flagellum organization
ACJ67_RS08910	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACJ67_RS08915	COG1766	The M ring may be actively involved in energy transduction
ACJ67_RS08920	COG1677	Flagellar hook-basal body complex protein FliE
ACJ67_RS08955	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACJ67_RS08965	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
ACJ67_RS08965	COG0028	Belongs to the TPP enzyme family
ACJ67_RS09000	COG1295	ribonuclease BN
ACJ67_RS09030	COG0322	excinuclease ABC activity
ACJ67_RS09050	COG1942	4-Oxalocrotonate Tautomerase
ACJ67_RS09055	COG1230	cation diffusion facilitator family transporter
ACJ67_RS09060	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ACJ67_RS09070	COG0784	Response regulator, receiver
ACJ67_RS09070	COG2198	Histidine kinase
ACJ67_RS09070	COG2205	protein histidine kinase activity
ACJ67_RS09080	COG1049	propionate catabolic process, 2-methylcitrate cycle
ACJ67_RS09110	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ACJ67_RS09120	COG1053	succinate dehydrogenase
ACJ67_RS09135	COG0281	malic enzyme
ACJ67_RS09140	COG2188	Transcriptional regulator
ACJ67_RS09145	COG2301	Belongs to the HpcH HpaI aldolase family
ACJ67_RS09150	COG2030	dehydratase
ACJ67_RS09170	COG2079	MmgE PrpD family protein
ACJ67_RS09185	COG2197	response regulator
ACJ67_RS09190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACJ67_RS09200	COG5001	Diguanylate cyclase
ACJ67_RS09245	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ACJ67_RS09250	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ACJ67_RS09265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACJ67_RS09280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACJ67_RS09290	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ACJ67_RS09295	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ACJ67_RS09300	COG0483	inositol monophosphate 1-phosphatase activity
ACJ67_RS09305	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ACJ67_RS09325	COG1104	cysteine desulfurase activity
ACJ67_RS09330	COG1104	cysteine desulfurase activity
ACJ67_RS09335	COG0822	iron-sulfur transferase activity
ACJ67_RS09345	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ACJ67_RS09350	COG0443	Heat shock 70 kDa protein
ACJ67_RS09360	COG0288	reversible hydration of carbon dioxide
ACJ67_RS09365	COG0659	secondary active sulfate transmembrane transporter activity
ACJ67_RS09380	COG2197	response regulator
ACJ67_RS09400	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACJ67_RS09400	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACJ67_RS09435	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ACJ67_RS09440	COG4208	sulfate ABC transporter
ACJ67_RS09445	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ACJ67_RS09455	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ACJ67_RS09460	COG1045	serine acetyltransferase
ACJ67_RS09465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACJ67_RS09470	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACJ67_RS09485	COG3706	GGDEF domain
ACJ67_RS09485	COG4251	negative regulation of phosphorylation
ACJ67_RS09485	COG2203	Gaf domain
ACJ67_RS09485	COG5001	Diguanylate cyclase
ACJ67_RS09515	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ACJ67_RS09520	COG2205	protein histidine kinase activity
ACJ67_RS09525	COG0745	RESPONSE REGULATOR receiver
ACJ67_RS09535	COG0488	(ABC) transporter
ACJ67_RS09545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACJ67_RS09550	COG0312	modulator of DNA gyrase
ACJ67_RS09585	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACJ67_RS09630	COG0840	transmembrane signaling receptor activity
ACJ67_RS09645	COG1074	ATP-dependent DNA helicase activity
ACJ67_RS09650	COG0778	Nitroreductase
ACJ67_RS09660	COG0586	Pfam SNARE associated Golgi protein
ACJ67_RS09665	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACJ67_RS09670	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ACJ67_RS09675	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ACJ67_RS09685	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ACJ67_RS09690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACJ67_RS09695	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ACJ67_RS09700	COG1674	ftsk spoiiie
ACJ67_RS09705	COG0783	Belongs to the Dps family
ACJ67_RS09710	COG0492	ferredoxin-NADP+ reductase activity
ACJ67_RS09715	COG2840	Smr protein MutS2
ACJ67_RS09730	COG0640	Transcriptional regulator
ACJ67_RS09745	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACJ67_RS09750	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ACJ67_RS09755	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACJ67_RS09770	COG1215	transferase activity, transferring glycosyl groups
ACJ67_RS09785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACJ67_RS09795	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ACJ67_RS09800	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ACJ67_RS09800	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ACJ67_RS09805	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACJ67_RS09820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACJ67_RS09825	COG0438	transferase activity, transferring glycosyl groups
ACJ67_RS09835	COG0668	transmembrane transport
ACJ67_RS09845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACJ67_RS09855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACJ67_RS09860	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ACJ67_RS09865	COG1534	Rna-binding protein
ACJ67_RS09880	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ACJ67_RS09885	COG0505	Belongs to the CarA family
ACJ67_RS09895	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ACJ67_RS09905	COG0735	belongs to the Fur family
ACJ67_RS09915	COG0497	DNA recombination
ACJ67_RS09920	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACJ67_RS09925	COG1420	regulation of RNA biosynthetic process
ACJ67_RS09940	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ACJ67_RS09950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACJ67_RS09955	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ACJ67_RS09960	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ACJ67_RS09960	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ACJ67_RS09985	COG3754	Rhamnan synthesis protein F
ACJ67_RS10000	COG0800	Aldolase
ACJ67_RS10010	COG2192	nodulation
ACJ67_RS10025	COG0505	Belongs to the CarA family
ACJ67_RS10030	COG1187	pseudouridine synthase activity
ACJ67_RS10040	COG1278	Cold shock
ACJ67_RS10060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACJ67_RS10065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACJ67_RS10070	COG0006	proline dipeptidase activity
ACJ67_RS10080	COG3530	Putative quorum-sensing-regulated virulence factor
ACJ67_RS10085	COG3706	GGDEF domain
ACJ67_RS10095	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACJ67_RS10100	COG3178	'Phosphotransferase
ACJ67_RS10105	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ACJ67_RS10110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACJ67_RS10115	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ACJ67_RS10120	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACJ67_RS10125	COG0563	adenylate kinase activity
ACJ67_RS10130	COG4772	TonB-dependent receptor
ACJ67_RS10135	COG0495	leucyl-tRNA aminoacylation
ACJ67_RS10150	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ACJ67_RS10155	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ACJ67_RS10160	COG1944	ATP diphosphatase activity
ACJ67_RS10190	COG0633	Ferredoxin
ACJ67_RS10200	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACJ67_RS10215	COG1595	DNA-templated transcription, initiation
ACJ67_RS10230	COG4774	siderophore transport
ACJ67_RS10235	COG3712	iron ion homeostasis
ACJ67_RS10250	COG0583	DNA-binding transcription factor activity
ACJ67_RS10265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACJ67_RS10270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACJ67_RS10280	COG4651	solute:proton antiporter activity
ACJ67_RS10280	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACJ67_RS10285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACJ67_RS10300	COG3707	response regulator
ACJ67_RS10305	COG2116	formate transmembrane transporter activity
ACJ67_RS10310	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
ACJ67_RS10315	COG0515	serine threonine protein kinase
ACJ67_RS10315	COG2815	serine threonine protein kinase
ACJ67_RS10320	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACJ67_RS10330	COG1116	anion transmembrane transporter activity
ACJ67_RS10345	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACJ67_RS10350	COG2223	nitrite transmembrane transporter activity
ACJ67_RS10355	COG2815	serine threonine protein kinase
ACJ67_RS10355	COG0515	serine threonine protein kinase
ACJ67_RS10365	COG0243	molybdopterin cofactor binding
ACJ67_RS10370	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACJ67_RS10375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACJ67_RS10375	COG2146	nitrite reductase [NAD(P)H] activity
ACJ67_RS10400	COG0697	spore germination
ACJ67_RS10405	COG0640	Transcriptional regulator
ACJ67_RS10415	COG1309	transcriptional regulator
ACJ67_RS10425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACJ67_RS10450	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ACJ67_RS10465	COG0004	ammonium transporteR
ACJ67_RS10480	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACJ67_RS10485	COG4772	TonB-dependent receptor
ACJ67_RS10490	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ACJ67_RS10495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACJ67_RS10535	COG3851	Histidine kinase
ACJ67_RS10550	COG2197	response regulator
ACJ67_RS10555	COG2201	protein-glutamate methylesterase activity
ACJ67_RS10590	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ACJ67_RS10595	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ACJ67_RS10605	COG0235	Class ii aldolase
ACJ67_RS10610	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ACJ67_RS10615	COG0084	hydrolase, TatD family'
ACJ67_RS10620	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACJ67_RS10620	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACJ67_RS10630	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ACJ67_RS10640	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ACJ67_RS10645	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACJ67_RS10655	COG2975	iron-sulfur cluster assembly
ACJ67_RS10680	COG0033	Phosphoglucomutase
ACJ67_RS10690	COG0730	response to heat
ACJ67_RS10705	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACJ67_RS10730	COG1943	Transposase
ACJ67_RS10790	COG0714	Associated with various cellular activities
ACJ67_RS10800	COG2010	Cytochrome c
ACJ67_RS10815	COG3851	Histidine kinase
ACJ67_RS10825	COG2197	response regulator
ACJ67_RS10875	COG0811	peptide transport
ACJ67_RS10895	COG0737	Belongs to the 5'-nucleotidase family
ACJ67_RS10915	COG2831	hemolysin activation secretion protein
ACJ67_RS10940	COG0741	lytic transglycosylase activity
ACJ67_RS10950	COG2165	general secretion pathway protein
ACJ67_RS10960	COG4796	Type ii and iii secretion system protein
ACJ67_RS10985	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACJ67_RS10990	COG1459	type II secretion system
ACJ67_RS11000	COG1132	(ABC) transporter
ACJ67_RS11005	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ACJ67_RS11010	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ACJ67_RS11050	COG0058	SHG alpha-glucan phosphorylase activity
ACJ67_RS11055	COG2885	chlorophyll binding
ACJ67_RS11075	COG0326	Molecular chaperone. Has ATPase activity
ACJ67_RS11095	COG0248	Ppx GppA phosphatase
ACJ67_RS11115	COG2062	phosphohistidine phosphatase, SixA
ACJ67_RS11125	COG3046	protein related to deoxyribodipyrimidine photolyase
ACJ67_RS11130	COG0149	triose-phosphate isomerase activity
ACJ67_RS11135	COG0191	fructose-bisphosphate aldolase activity
ACJ67_RS11140	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ACJ67_RS11145	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ACJ67_RS11150	COG4585	Histidine kinase
ACJ67_RS11155	COG2197	response regulator
ACJ67_RS11185	COG0736	holo-[acyl-carrier-protein] synthase activity
ACJ67_RS11190	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ACJ67_RS11205	COG1381	Involved in DNA repair and RecF pathway recombination
ACJ67_RS11210	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ACJ67_RS11215	COG0571	ribonuclease III activity
ACJ67_RS11230	COG0481	GTPase activity
ACJ67_RS11235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACJ67_RS11240	COG3026	antisigma factor binding
ACJ67_RS11250	COG1595	DNA-templated transcription, initiation
ACJ67_RS11255	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ACJ67_RS11260	COG1525	nuclease
ACJ67_RS11270	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACJ67_RS11275	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ACJ67_RS11280	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ACJ67_RS11285	COG0149	triose-phosphate isomerase activity
ACJ67_RS11295	COG2850	peptidyl-arginine hydroxylation
ACJ67_RS11340	COG1648	precorrin-2 dehydrogenase activity
ACJ67_RS11340	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACJ67_RS11345	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACJ67_RS11350	COG1702	phosphate starvation-inducible protein PhoH
ACJ67_RS11365	COG0167	dihydroorotate dehydrogenase activity
ACJ67_RS11375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACJ67_RS11380	COG1981	membrane
ACJ67_RS11400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACJ67_RS11425	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ACJ67_RS11430	COG3245	cytochrome
ACJ67_RS11440	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACJ67_RS11465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACJ67_RS11485	COG2267	carboxylic ester hydrolase activity
ACJ67_RS11490	COG0671	phosphoesterase, PA-phosphatase related
ACJ67_RS11500	COG1597	lipid kinase activity
ACJ67_RS11510	COG0243	molybdopterin cofactor binding
ACJ67_RS11535	COG0583	DNA-binding transcription factor activity
ACJ67_RS11550	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ACJ67_RS11580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACJ67_RS11605	COG0387	Pfam Sodium calcium exchanger
ACJ67_RS11610	COG1064	alcohol dehydrogenase
ACJ67_RS11615	COG2207	Transcriptional regulator
ACJ67_RS11635	COG0109	protoheme IX farnesyltransferase activity
ACJ67_RS11640	COG1612	heme a metabolic process
ACJ67_RS11660	COG1845	cytochrome c oxidase, subunit III
ACJ67_RS11665	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ACJ67_RS11670	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACJ67_RS11690	COG5001	Diguanylate cyclase
ACJ67_RS11690	COG3300	MHYT domain
ACJ67_RS11695	COG4774	siderophore transport
ACJ67_RS11735	COG0582	viral genome integration into host DNA
ACJ67_RS11745	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ACJ67_RS11760	COG0442	prolyl-tRNA aminoacylation
ACJ67_RS11775	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ACJ67_RS11790	COG0456	acetyltransferase
ACJ67_RS11795	COG1214	PFAM Peptidase M22, glycoprotease
ACJ67_RS11800	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ACJ67_RS11805	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ACJ67_RS11810	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACJ67_RS11820	COG2096	Adenosyltransferase
ACJ67_RS11825	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ACJ67_RS11840	COG1999	signal sequence binding
ACJ67_RS11880	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ACJ67_RS11885	COG0751	glycine-tRNA ligase activity
ACJ67_RS11890	COG0752	glycyl-tRNA synthetase alpha subunit
ACJ67_RS11905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACJ67_RS11915	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ACJ67_RS11930	COG0463	Glycosyl transferase, family 2
ACJ67_RS11940	COG0745	RESPONSE REGULATOR receiver
ACJ67_RS11945	COG2223	nitrite transmembrane transporter activity
ACJ67_RS11950	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ACJ67_RS11955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACJ67_RS11960	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACJ67_RS11970	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACJ67_RS11990	COG0215	cysteine-tRNA ligase activity
ACJ67_RS12005	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ACJ67_RS12015	COG1199	ATP-dependent helicase activity
ACJ67_RS12020	COG0791	NLP P60 protein
ACJ67_RS12030	COG0793	Belongs to the peptidase S41A family
ACJ67_RS12035	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ACJ67_RS12050	COG1765	OsmC-like protein
ACJ67_RS12060	COG2027	D-alanyl-D-alanine carboxypeptidase
ACJ67_RS12080	COG0826	peptidase U32
ACJ67_RS12085	COG2095	MarC family integral membrane protein
ACJ67_RS12095	COG0482	sulfurtransferase activity
ACJ67_RS12105	COG4771	TonB-dependent receptor
ACJ67_RS12120	COG0625	glutathione transferase activity
ACJ67_RS12130	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACJ67_RS12135	COG1136	(ABC) transporter
ACJ67_RS12135	COG0577	efflux transmembrane transporter activity
ACJ67_RS12140	COG0577	efflux transmembrane transporter activity
ACJ67_RS12140	COG1136	(ABC) transporter
ACJ67_RS12170	COG3128	pkhd-type hydroxylase
ACJ67_RS12175	COG4774	siderophore transport
ACJ67_RS12190	COG4774	siderophore transport
ACJ67_RS12205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACJ67_RS12210	COG4558	Periplasmic binding protein
ACJ67_RS12220	COG0748	coenzyme F420 binding
ACJ67_RS12260	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACJ67_RS12270	COG0028	Belongs to the TPP enzyme family
ACJ67_RS12275	COG0440	acetolactate synthase activity
ACJ67_RS12280	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ACJ67_RS12285	COG0688	phosphatidylethanolamine metabolic process
ACJ67_RS12300	COG0308	aminopeptidase N
ACJ67_RS12310	COG3093	addiction module antidote protein HigA
ACJ67_RS12330	COG2161	toxin-antitoxin pair type II binding
ACJ67_RS12345	COG2824	Alkylphosphonate utilization operon protein PhnA
ACJ67_RS12355	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACJ67_RS12360	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
ACJ67_RS12370	COG2197	response regulator
ACJ67_RS12380	COG3851	Histidine kinase
ACJ67_RS12405	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACJ67_RS12415	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACJ67_RS12420	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ACJ67_RS12420	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACJ67_RS12425	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACJ67_RS12430	COG0625	glutathione transferase activity
ACJ67_RS12450	COG5001	Diguanylate cyclase
ACJ67_RS12450	COG3706	GGDEF domain
ACJ67_RS12450	COG2203	Gaf domain
ACJ67_RS12450	COG4251	negative regulation of phosphorylation
ACJ67_RS12455	COG0617	tRNA 3'-terminal CCA addition
ACJ67_RS12465	COG0741	lytic transglycosylase activity
ACJ67_RS12475	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ACJ67_RS12490	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ACJ67_RS12495	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACJ67_RS12500	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ACJ67_RS12505	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACJ67_RS12510	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ACJ67_RS12515	COG0772	Belongs to the SEDS family
ACJ67_RS12520	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ACJ67_RS12525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACJ67_RS12530	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACJ67_RS12535	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACJ67_RS12550	COG0275	rRNA processing
ACJ67_RS12555	COG2001	Belongs to the MraZ family
ACJ67_RS12575	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ACJ67_RS12580	COG0418	dihydroorotase activity
ACJ67_RS12590	COG0792	nuclease activity
ACJ67_RS12595	COG2823	Periplasmic or secreted lipoprotein
ACJ67_RS12605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACJ67_RS12615	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ACJ67_RS12620	COG0254	rRNA binding
ACJ67_RS12635	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ACJ67_RS12640	COG3383	formate dehydrogenase (NAD+) activity
ACJ67_RS12655	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACJ67_RS12660	COG0746	molybdenum cofactor guanylyltransferase activity
ACJ67_RS12665	COG0303	'Molybdopterin
ACJ67_RS12670	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ACJ67_RS12675	COG4191	Histidine kinase
ACJ67_RS12680	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACJ67_RS12685	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ACJ67_RS12690	COG0477	Major facilitator Superfamily
ACJ67_RS12695	COG1252	NADH dehydrogenase
ACJ67_RS12710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACJ67_RS12725	COG1295	ribonuclease BN
ACJ67_RS12745	COG2067	long-chain fatty acid transport protein
ACJ67_RS12775	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
ACJ67_RS12780	COG2124	cytochrome p450
ACJ67_RS12790	COG2323	membrane
ACJ67_RS12795	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ACJ67_RS12875	COG0798	PFAM Bile acid sodium symporter
ACJ67_RS12880	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACJ67_RS12915	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ACJ67_RS12920	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ACJ67_RS12925	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ACJ67_RS12930	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ACJ67_RS12945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACJ67_RS12945	COG2169	Transcriptional regulator
ACJ67_RS12950	COG0335	large ribosomal subunit rRNA binding
ACJ67_RS12955	COG0336	Belongs to the RNA methyltransferase TrmD family
ACJ67_RS12960	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACJ67_RS12965	COG0228	four-way junction DNA binding
ACJ67_RS12970	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACJ67_RS12990	COG0823	Involved in the tonB-independent uptake of proteins
ACJ67_RS13010	COG0824	Thioesterase
ACJ67_RS13015	COG2255	four-way junction helicase activity
ACJ67_RS13020	COG0632	four-way junction helicase activity
ACJ67_RS13025	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ACJ67_RS13030	COG0217	transcriptional regulatory protein
ACJ67_RS13035	COG0697	spore germination
ACJ67_RS13045	COG1846	Transcriptional regulator
ACJ67_RS13055	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ACJ67_RS13060	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ACJ67_RS13065	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ACJ67_RS13075	COG2205	protein histidine kinase activity
ACJ67_RS13080	COG0745	RESPONSE REGULATOR receiver
ACJ67_RS13085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACJ67_RS13095	COG0517	IMP dehydrogenase activity
ACJ67_RS13095	COG0516	GMP reductase activity
ACJ67_RS13100	COG0826	peptidase U32
ACJ67_RS13120	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACJ67_RS13125	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ACJ67_RS13145	COG0509	glycine decarboxylation via glycine cleavage system
ACJ67_RS13185	COG3023	N-Acetylmuramoyl-L-alanine amidase
ACJ67_RS13210	COG1301	dicarboxylic acid transport
ACJ67_RS13220	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACJ67_RS13220	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACJ67_RS13235	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ACJ67_RS13240	COG0628	permease
ACJ67_RS13245	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ACJ67_RS13255	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ACJ67_RS13260	COG3634	alkyl hydroperoxide reductase activity
ACJ67_RS13280	COG0315	cyclic pyranopterin monophosphate synthase activity
ACJ67_RS13305	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ACJ67_RS13310	COG1137	ATPase activity
ACJ67_RS13315	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ACJ67_RS13320	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACJ67_RS13325	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ACJ67_RS13330	COG0372	Belongs to the citrate synthase family
ACJ67_RS13335	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ACJ67_RS13355	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ACJ67_RS13360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACJ67_RS13365	COG0316	Belongs to the HesB IscA family
ACJ67_RS13380	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ACJ67_RS13385	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACJ67_RS13390	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ACJ67_RS13405	COG3161	chorismate lyase activity
ACJ67_RS13410	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ACJ67_RS13415	COG2967	ApaG domain
ACJ67_RS13420	COG2022	thiamine diphosphate biosynthetic process
ACJ67_RS13435	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ACJ67_RS13450	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ACJ67_RS13455	COG0070	glutamate synthase
ACJ67_RS13455	COG0069	glutamate synthase activity
ACJ67_RS13455	COG0067	glutamate synthase
ACJ67_RS13465	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ACJ67_RS13470	COG3038	cytochrome b561
ACJ67_RS13480	COG4221	oxidoreductase activity
ACJ67_RS13490	COG0318	PFAM AMP-dependent synthetase and ligase
ACJ67_RS13500	COG2194	sulfuric ester hydrolase activity
ACJ67_RS13525	COG4191	Histidine kinase
ACJ67_RS13530	COG2204	response regulator
ACJ67_RS13535	COG3384	dioxygenase
ACJ67_RS13540	COG2259	Doxx family
ACJ67_RS13545	COG0583	DNA-binding transcription factor activity
ACJ67_RS13550	COG2259	Doxx family
ACJ67_RS13560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACJ67_RS13570	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ACJ67_RS13575	COG1538	Outer membrane efflux protein
ACJ67_RS13600	COG0864	Transcriptional regulator
ACJ67_RS13610	COG1185	polyribonucleotide nucleotidyltransferase activity
ACJ67_RS13615	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ACJ67_RS13630	COG1054	Belongs to the UPF0176 family
ACJ67_RS13645	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACJ67_RS13650	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ACJ67_RS13655	COG0704	Plays a role in the regulation of phosphate uptake
ACJ67_RS13675	COG0123	including yeast histone deacetylase and acetoin utilization protein
ACJ67_RS13680	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACJ67_RS13685	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ACJ67_RS13690	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ACJ67_RS13695	COG0195	Participates in both transcription termination and antitermination
ACJ67_RS13695	COG2251	uridine kinase activity
ACJ67_RS13700	COG0779	Required for maturation of 30S ribosomal subunits
ACJ67_RS13735	COG0009	L-threonylcarbamoyladenylate synthase
ACJ67_RS13785	COG0431	NADPH-dependent FMN reductase
ACJ67_RS13795	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACJ67_RS13795	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACJ67_RS13810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACJ67_RS13815	COG3829	transcription factor binding
ACJ67_RS13820	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACJ67_RS13830	COG0069	glutamate synthase activity
ACJ67_RS13840	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ACJ67_RS13855	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ACJ67_RS13855	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACJ67_RS13885	COG0642	Histidine kinase
ACJ67_RS13920	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACJ67_RS13925	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACJ67_RS13950	COG2132	Multicopper oxidase
ACJ67_RS14000	COG0629	single-stranded DNA binding
ACJ67_RS14005	COG2814	Major facilitator Superfamily
ACJ67_RS14015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACJ67_RS14020	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ACJ67_RS14030	COG0174	glutamine synthetase
ACJ67_RS14040	COG3852	Histidine kinase
ACJ67_RS14045	COG2204	response regulator
ACJ67_RS14065	COG1194	a g-specific adenine glycosylase
ACJ67_RS14075	COG1968	undecaprenyl-diphosphatase activity
ACJ67_RS14080	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ACJ67_RS14095	COG2264	protein methyltransferase activity
ACJ67_RS14100	COG0439	Biotin carboxylase
ACJ67_RS14105	COG0511	ligase activity, forming carbon-carbon bonds
ACJ67_RS14110	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ACJ67_RS14115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACJ67_RS14120	COG4232	protein-disulfide reductase activity
ACJ67_RS14140	COG2814	Major facilitator Superfamily
ACJ67_RS14145	COG4654	Cytochrome c, class I
ACJ67_RS14155	COG3284	Transcriptional regulator
ACJ67_RS14165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACJ67_RS14180	COG4335	DNA alkylation repair
ACJ67_RS14185	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ACJ67_RS14190	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ACJ67_RS14195	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ACJ67_RS14200	COG0546	phosphoglycolate phosphatase activity
ACJ67_RS14215	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACJ67_RS14225	COG0134	indole-3-glycerol-phosphate synthase activity
ACJ67_RS14245	COG0708	Exodeoxyribonuclease III
ACJ67_RS14250	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ACJ67_RS14265	COG1187	pseudouridine synthase activity
ACJ67_RS14270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACJ67_RS14275	COG3411	Ferredoxin
ACJ67_RS14285	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACJ67_RS14290	COG0352	thiamine-phosphate diphosphorylase activity
ACJ67_RS14295	COG0351	phosphomethylpyrimidine kinase
ACJ67_RS14315	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACJ67_RS14320	COG0018	arginyl-trna synthetase
ACJ67_RS14345	COG1028	Short-chain dehydrogenase reductase Sdr
ACJ67_RS14350	COG3422	double-strand break repair
ACJ67_RS14365	COG0488	(ABC) transporter
ACJ67_RS14375	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ACJ67_RS14380	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACJ67_RS14385	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ACJ67_RS14390	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ACJ67_RS14395	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ACJ67_RS14400	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ACJ67_RS14405	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ACJ67_RS14410	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACJ67_RS14415	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ACJ67_RS14425	COG0356	it plays a direct role in the translocation of protons across the membrane
ACJ67_RS14440	COG1192	Involved in chromosome partitioning
ACJ67_RS14445	COG0357	Ribosomal RNA small subunit methyltransferase G
ACJ67_RS14450	COG0445	tRNA wobble uridine modification
ACJ67_RS14465	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ACJ67_RS14470	COG0706	membrane insertase activity
ACJ67_RS14475	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ACJ67_RS14480	COG0594	ribonuclease P activity
ACJ67_RS14485	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ACJ67_RS14500	COG2207	Transcriptional regulator
ACJ67_RS14505	COG0840	transmembrane signaling receptor activity