locus-tag	class	description
MPOP_RS00005	COG0268	Binds directly to 16S ribosomal RNA
MPOP_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MPOP_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MPOP_RS00030	COG0514	ATP-dependent DNA helicase (RecQ)
MPOP_RS00040	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MPOP_RS00050	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MPOP_RS00060	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MPOP_RS00090	COG0437	4 iron, 4 sulfur cluster binding
MPOP_RS00125	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MPOP_RS00190	COG4191	Histidine kinase
MPOP_RS00190	COG0784	Response regulator, receiver
MPOP_RS00200	COG4191	Histidine kinase
MPOP_RS00200	COG0784	Response regulator, receiver
MPOP_RS00210	COG1028	Short-chain dehydrogenase reductase Sdr
MPOP_RS00215	COG2186	Transcriptional regulator
MPOP_RS00235	COG3052	prosthetic group binding
MPOP_RS00255	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
MPOP_RS00265	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MPOP_RS00270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MPOP_RS00295	COG2144	transferase activity, transferring acyl groups
MPOP_RS00305	COG0438	transferase activity, transferring glycosyl groups
MPOP_RS00315	COG2072	flavoprotein involved in K transport
MPOP_RS00350	COG1484	DNA-dependent DNA replication
MPOP_RS00480	COG0784	Response regulator, receiver
MPOP_RS00480	COG4191	Histidine kinase
MPOP_RS00490	COG3609	addiction module antidote protein, CC2985 family
MPOP_RS00570	COG2391	methyltransferase activity
MPOP_RS00575	COG2391	methyltransferase activity
MPOP_RS00590	COG1388	LysM domain
MPOP_RS00590	COG1376	ErfK ybiS ycfS ynhG family protein
MPOP_RS00600	COG4232	protein-disulfide reductase activity
MPOP_RS00635	COG0640	Transcriptional regulator
MPOP_RS00645	COG0784	Response regulator, receiver
MPOP_RS00645	COG4191	Histidine kinase
MPOP_RS00680	COG3300	MHYT domain
MPOP_RS00680	COG5001	Diguanylate cyclase
MPOP_RS00690	COG0840	transmembrane signaling receptor activity
MPOP_RS00700	COG1295	ribonuclease BN
MPOP_RS00720	COG0784	Response regulator, receiver
MPOP_RS00720	COG4191	Histidine kinase
MPOP_RS00725	COG4191	Histidine kinase
MPOP_RS00725	COG0784	Response regulator, receiver
MPOP_RS00760	COG3328	transposase activity
MPOP_RS00780	COG1028	Short-chain dehydrogenase reductase Sdr
MPOP_RS00805	COG3920	Histidine kinase
MPOP_RS00845	COG5001	Diguanylate cyclase
MPOP_RS00845	COG3706	GGDEF domain
MPOP_RS00845	COG2203	Gaf domain
MPOP_RS00845	COG4251	negative regulation of phosphorylation
MPOP_RS00865	COG3158	transport of potassium into the cell
MPOP_RS00985	COG0133	tryptophan synthase activity
MPOP_RS00990	COG0135	phosphoribosylanthranilate isomerase activity
MPOP_RS01000	COG0776	regulation of translation
MPOP_RS01005	COG0616	signal peptide processing
MPOP_RS01015	COG0539	negative regulation of cytoplasmic translation
MPOP_RS01020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MPOP_RS01050	COG2855	membrane
MPOP_RS01065	COG0531	amino acid
MPOP_RS01100	COG0488	(ABC) transporter
MPOP_RS01125	COG0725	ABC transporter, periplasmic molybdate-binding protein
MPOP_RS01150	COG2080	2 iron, 2 sulfur cluster binding
MPOP_RS01155	COG2010	Cytochrome c
MPOP_RS01155	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MPOP_RS01170	COG1289	transmembrane transporter activity
MPOP_RS01225	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
MPOP_RS01250	COG0438	transferase activity, transferring glycosyl groups
MPOP_RS01260	COG0583	DNA-binding transcription factor activity
MPOP_RS01265	COG1028	Short-chain dehydrogenase reductase Sdr
MPOP_RS01270	COG3959	Transketolase, thiamine diphosphate binding domain
MPOP_RS01275	COG3958	Transketolase
MPOP_RS01280	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MPOP_RS01285	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MPOP_RS01295	COG1063	alcohol dehydrogenase
MPOP_RS01300	COG3328	transposase activity
MPOP_RS01325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MPOP_RS01400	COG0438	transferase activity, transferring glycosyl groups
MPOP_RS01405	COG0438	transferase activity, transferring glycosyl groups
MPOP_RS01425	COG0438	transferase activity, transferring glycosyl groups
MPOP_RS01445	COG3383	formate dehydrogenase (NAD+) activity
MPOP_RS01465	COG0753	catalase activity
MPOP_RS01475	COG1595	DNA-templated transcription, initiation
MPOP_RS01495	COG0628	permease
MPOP_RS01505	COG0586	Pfam SNARE associated Golgi protein
MPOP_RS01515	COG3158	transport of potassium into the cell
MPOP_RS01520	COG2202	Pas domain
MPOP_RS01520	COG3920	Histidine kinase
MPOP_RS01540	COG0784	Response regulator, receiver
MPOP_RS01540	COG4191	Histidine kinase
MPOP_RS01550	COG2202	Pas domain
MPOP_RS01550	COG3920	Histidine kinase
MPOP_RS01550	COG2202	Pas domain
MPOP_RS01550	COG3920	Histidine kinase
MPOP_RS01580	COG0693	protein deglycase activity
MPOP_RS01585	COG1028	Short-chain dehydrogenase reductase Sdr
MPOP_RS01590	COG0783	Belongs to the Dps family
MPOP_RS01600	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MPOP_RS01695	COG3328	transposase activity
MPOP_RS01715	COG2197	response regulator
MPOP_RS01735	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MPOP_RS01740	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MPOP_RS01745	COG0443	Heat shock 70 kDa protein
MPOP_RS01760	COG0546	phosphoglycolate phosphatase activity
MPOP_RS01770	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MPOP_RS01785	COG1309	transcriptional regulator
MPOP_RS01790	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MPOP_RS01805	COG0604	alcohol dehydrogenase
MPOP_RS01810	COG0753	catalase activity
MPOP_RS01815	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MPOP_RS01815	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MPOP_RS01825	COG1028	Short-chain dehydrogenase reductase Sdr
MPOP_RS01830	COG0640	Transcriptional regulator
MPOP_RS01835	COG0180	Tryptophanyl-tRNA synthetase
MPOP_RS01840	COG0066	3-isopropylmalate dehydratase activity
MPOP_RS01845	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MPOP_RS01850	COG1703	isobutyryl-CoA mutase activity
MPOP_RS01870	COG1388	LysM domain
MPOP_RS01870	COG1376	ErfK ybiS ycfS ynhG family protein
MPOP_RS01880	COG0420	3'-5' exonuclease activity
MPOP_RS01885	COG0419	ATPase involved in DNA repair
MPOP_RS01890	COG2223	nitrite transmembrane transporter activity
MPOP_RS01905	COG2226	methyltransferase
MPOP_RS01920	COG0494	nUDIX hydrolase
MPOP_RS01930	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MPOP_RS01975	COG0210	DNA helicase
MPOP_RS01985	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MPOP_RS01995	COG2140	Oxalate decarboxylase
MPOP_RS02000	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MPOP_RS02015	COG0745	RESPONSE REGULATOR receiver
MPOP_RS02040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MPOP_RS02055	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MPOP_RS02060	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MPOP_RS02075	COG0077	Prephenate dehydratase
MPOP_RS02080	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MPOP_RS02090	COG4166	transmembrane transport
MPOP_RS02095	COG4166	transmembrane transport
MPOP_RS02100	COG4174	ABC transporter (Permease)
MPOP_RS02115	COG0463	Glycosyl transferase, family 2
MPOP_RS02125	COG1309	transcriptional regulator
MPOP_RS02155	COG0071	Belongs to the small heat shock protein (HSP20) family
MPOP_RS02165	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MPOP_RS02180	COG2967	ApaG domain
MPOP_RS02185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MPOP_RS02190	COG3781	membrane
MPOP_RS02195	COG2116	formate transmembrane transporter activity
MPOP_RS02200	COG1546	Belongs to the CinA family
MPOP_RS02200	COG1058	Belongs to the CinA family
MPOP_RS02205	COG1489	DNA binding
MPOP_RS02225	COG0842	Transport permease protein
MPOP_RS02230	COG1131	(ABC) transporter
MPOP_RS02275	COG0243	molybdopterin cofactor binding
MPOP_RS02275	COG3383	formate dehydrogenase (NAD+) activity
MPOP_RS02280	COG0437	4 iron, 4 sulfur cluster binding
MPOP_RS02285	COG2864	formate dehydrogenase
MPOP_RS02335	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MPOP_RS02340	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MPOP_RS02345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MPOP_RS02355	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MPOP_RS02360	COG0792	nuclease activity
MPOP_RS02370	COG1732	Glycine betaine
MPOP_RS02375	COG1174	glycine betaine transport
MPOP_RS02380	COG1174	glycine betaine transport
MPOP_RS02395	COG1335	isochorismatase
MPOP_RS02400	COG1376	ErfK ybiS ycfS ynhG family protein
MPOP_RS02415	COG2759	Belongs to the formate--tetrahydrofolate ligase family
MPOP_RS02440	COG0745	RESPONSE REGULATOR receiver
MPOP_RS02445	COG0196	riboflavin kinase activity
MPOP_RS02465	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MPOP_RS02475	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MPOP_RS02480	COG1338	Plays a role in the flagellum-specific transport system
MPOP_RS02485	COG2259	Doxx family
MPOP_RS02505	COG4957	zinc ion binding
MPOP_RS02520	COG2166	iron-sulfur cluster assembly
MPOP_RS02525	COG3920	Histidine kinase
MPOP_RS02550	COG0308	aminopeptidase N
MPOP_RS02555	COG2205	protein histidine kinase activity
MPOP_RS02555	COG2202	Pas domain
MPOP_RS02565	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MPOP_RS02575	COG1324	tolerance protein
MPOP_RS02580	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MPOP_RS02590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MPOP_RS02590	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MPOP_RS02610	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MPOP_RS02620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MPOP_RS02625	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MPOP_RS02630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MPOP_RS02635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MPOP_RS02645	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MPOP_RS02650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MPOP_RS02655	COG1129	ABC transporter
MPOP_RS02655	COG0842	Transport permease protein
MPOP_RS02660	COG0842	Transport permease protein
MPOP_RS02665	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
MPOP_RS02670	COG4251	negative regulation of phosphorylation
MPOP_RS02675	COG0784	Response regulator, receiver
MPOP_RS02690	COG3842	ATPase activity
MPOP_RS02695	COG1840	ABC-type Fe3 transport system, periplasmic component
MPOP_RS02725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MPOP_RS02745	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MPOP_RS02755	COG4208	sulfate ABC transporter
MPOP_RS02760	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MPOP_RS02800	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MPOP_RS02805	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MPOP_RS02815	COG0438	transferase activity, transferring glycosyl groups
MPOP_RS02815	COG1216	Glycosyl transferase, family 2
MPOP_RS02850	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
MPOP_RS02860	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MPOP_RS02865	COG0047	phosphoribosylformylglycinamidine synthase activity
MPOP_RS02870	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MPOP_RS02875	COG0483	inositol monophosphate 1-phosphatase activity
MPOP_RS02885	COG2022	thiamine diphosphate biosynthetic process
MPOP_RS02895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MPOP_RS02895	COG2022	thiamine diphosphate biosynthetic process
MPOP_RS02925	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MPOP_RS02930	COG0358	DNA primase activity
MPOP_RS02935	COG3386	PFAM SMP-30 Gluconolaconase
MPOP_RS02950	COG0505	Belongs to the CarA family
MPOP_RS02965	COG3609	addiction module antidote protein, CC2985 family
MPOP_RS02975	COG1815	bacterial-type flagellum-dependent cell motility
MPOP_RS02980	COG1558	bacterial-type flagellum-dependent cell motility
MPOP_RS02990	COG4786	Flagellar basal body rod
MPOP_RS03000	COG1706	bacterial-type flagellum-dependent cell motility
MPOP_RS03010	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
MPOP_RS03020	COG1338	Plays a role in the flagellum-specific transport system
MPOP_RS03075	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MPOP_RS03080	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MPOP_RS03085	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MPOP_RS03105	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MPOP_RS03110	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MPOP_RS03115	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MPOP_RS03120	COG5006	permease, DMT superfamily
MPOP_RS03145	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MPOP_RS03155	COG0228	four-way junction DNA binding
MPOP_RS03160	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MPOP_RS03180	COG0336	Belongs to the RNA methyltransferase TrmD family
MPOP_RS03185	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MPOP_RS03190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MPOP_RS03200	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MPOP_RS03215	COG1132	(ABC) transporter
MPOP_RS03220	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MPOP_RS03230	COG0408	coproporphyrinogen oxidase activity
MPOP_RS03235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MPOP_RS03240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MPOP_RS03270	COG4786	Flagellar basal body rod
MPOP_RS03275	COG1157	protein secretion by the type III secretion system
MPOP_RS03310	COG4794	Type iii secretion
MPOP_RS03315	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MPOP_RS03360	COG2205	protein histidine kinase activity
MPOP_RS03370	COG1294	oxidase, subunit
MPOP_RS03380	COG0583	DNA-binding transcription factor activity
MPOP_RS03395	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MPOP_RS03420	COG0123	including yeast histone deacetylase and acetoin utilization protein
MPOP_RS03450	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MPOP_RS03450	COG0519	Catalyzes the synthesis of GMP from XMP
MPOP_RS03455	COG0667	Aldo Keto reductase
MPOP_RS03460	COG2207	Transcriptional regulator
MPOP_RS03470	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MPOP_RS03475	COG1393	Belongs to the ArsC family
MPOP_RS03485	COG0431	NADPH-dependent FMN reductase
MPOP_RS03510	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MPOP_RS03520	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MPOP_RS03615	COG0583	DNA-binding transcription factor activity
MPOP_RS03620	COG0300	oxidoreductase activity
MPOP_RS03665	COG4691	Plasmid stability protein
MPOP_RS03670	COG1487	ribonuclease activity
MPOP_RS03730	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MPOP_RS03760	COG0745	RESPONSE REGULATOR receiver
MPOP_RS03770	COG0110	maltose O-acetyltransferase activity
MPOP_RS03775	COG0281	malic enzyme
MPOP_RS03775	COG0280	phosphate acetyltransferase
MPOP_RS03815	COG2080	2 iron, 2 sulfur cluster binding
MPOP_RS03820	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MPOP_RS03825	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MPOP_RS03830	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MPOP_RS03840	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MPOP_RS03905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MPOP_RS03910	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MPOP_RS03910	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MPOP_RS03915	COG0509	glycine decarboxylation via glycine cleavage system
MPOP_RS03920	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MPOP_RS03930	COG0156	8-amino-7-oxononanoate synthase activity
MPOP_RS03935	COG0791	NLP P60 protein
MPOP_RS03965	COG0714	Associated with various cellular activities
MPOP_RS03980	COG2304	oxidoreductase activity
MPOP_RS04020	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MPOP_RS04030	COG3920	Histidine kinase
MPOP_RS04030	COG2202	Pas domain
MPOP_RS04035	COG0318	PFAM AMP-dependent synthetase and ligase
MPOP_RS04065	COG0693	protein deglycase activity
MPOP_RS04085	COG1278	Cold shock
MPOP_RS04105	COG2814	Major facilitator Superfamily
MPOP_RS04110	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MPOP_RS04115	COG1127	ABC transporter
MPOP_RS04130	COG0483	inositol monophosphate 1-phosphatase activity
MPOP_RS04200	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MPOP_RS04250	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
MPOP_RS04255	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MPOP_RS04260	COG2205	protein histidine kinase activity
MPOP_RS04275	COG3920	Histidine kinase
MPOP_RS04280	COG0154	amidase activity
MPOP_RS04300	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MPOP_RS04315	COG0277	FAD linked oxidase domain protein
MPOP_RS04325	COG1846	Transcriptional regulator
MPOP_RS04340	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MPOP_RS04345	COG2983	Belongs to the UPF0260 family
MPOP_RS04370	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MPOP_RS04375	COG2094	Belongs to the DNA glycosylase MPG family
MPOP_RS04380	COG0328	RNA-DNA hybrid ribonuclease activity
MPOP_RS04400	COG0189	ligase activity
MPOP_RS04405	COG0025	NhaP-type Na H and K H
MPOP_RS04410	COG3023	N-Acetylmuramoyl-L-alanine amidase
MPOP_RS04415	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MPOP_RS04425	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MPOP_RS04435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MPOP_RS04440	COG5001	Diguanylate cyclase
MPOP_RS04445	COG0745	RESPONSE REGULATOR receiver
MPOP_RS04455	COG1749	Flagellar hook protein flgE
MPOP_RS04475	COG2890	protein-(glutamine-N5) methyltransferase activity
MPOP_RS04480	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MPOP_RS04485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MPOP_RS04490	COG0527	aspartate kinase activity
MPOP_RS04495	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MPOP_RS04505	COG0604	alcohol dehydrogenase
MPOP_RS04505	COG1028	Short-chain dehydrogenase reductase Sdr
MPOP_RS04505	COG3321	synthase
MPOP_RS04510	COG1858	cytochrome C peroxidase
MPOP_RS04520	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MPOP_RS04525	COG2353	YceI-like domain
MPOP_RS04530	COG0632	four-way junction helicase activity
MPOP_RS04540	COG0784	Response regulator, receiver
MPOP_RS04550	COG1959	2 iron, 2 sulfur cluster binding
MPOP_RS04555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MPOP_RS04555	COG1017	nitric oxide dioxygenase activity
MPOP_RS04570	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MPOP_RS04590	COG0583	DNA-binding transcription factor activity
MPOP_RS04595	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
MPOP_RS04610	COG0217	transcriptional regulatory protein
MPOP_RS04615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MPOP_RS04655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MPOP_RS04670	COG1982	Orn Lys Arg decarboxylase major
MPOP_RS04680	COG0521	Mo-molybdopterin cofactor biosynthetic process
MPOP_RS04685	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MPOP_RS04700	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MPOP_RS04710	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MPOP_RS04720	COG3328	transposase activity
MPOP_RS04740	COG0564	pseudouridine synthase activity
MPOP_RS04760	COG2205	protein histidine kinase activity
MPOP_RS04765	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MPOP_RS04770	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MPOP_RS04780	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MPOP_RS04815	COG0739	heme binding
MPOP_RS04825	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MPOP_RS04840	COG0326	Molecular chaperone. Has ATPase activity
MPOP_RS04860	COG4106	trans-aconitate 2-methyltransferase activity
MPOP_RS04890	COG1797	cobyrinic acid a,c-diamide synthase activity
MPOP_RS04895	COG1396	sequence-specific DNA binding
MPOP_RS04905	COG2223	nitrite transmembrane transporter activity
MPOP_RS04910	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MPOP_RS04915	COG0735	belongs to the Fur family
MPOP_RS04920	COG1121	(ABC) transporter
MPOP_RS04930	COG3932	Exopolysaccharide synthesis, ExoD
MPOP_RS04940	COG1028	Short-chain dehydrogenase reductase Sdr
MPOP_RS04960	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MPOP_RS04960	COG3608	succinylglutamate desuccinylase aspartoacylase
MPOP_RS04970	COG0683	leucine binding
MPOP_RS04975	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MPOP_RS04980	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MPOP_RS04985	COG1381	Involved in DNA repair and RecF pathway recombination
MPOP_RS05020	COG1136	(ABC) transporter
MPOP_RS05030	COG0442	prolyl-tRNA aminoacylation
MPOP_RS05040	COG0346	lactoylglutathione lyase activity
MPOP_RS05055	COG1007	ATP synthesis coupled electron transport
MPOP_RS05070	COG0713	ATP synthesis coupled electron transport
MPOP_RS05080	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MPOP_RS05085	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MPOP_RS05095	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MPOP_RS05105	COG0649	NAD binding
MPOP_RS05110	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MPOP_RS05115	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MPOP_RS05120	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MPOP_RS05135	COG3794	PFAM blue (type 1) copper domain protein
MPOP_RS05140	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MPOP_RS05145	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MPOP_RS05160	COG0492	ferredoxin-NADP+ reductase activity
MPOP_RS05165	COG0583	DNA-binding transcription factor activity
MPOP_RS05170	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MPOP_RS05175	COG0511	ligase activity, forming carbon-carbon bonds
MPOP_RS05180	COG0439	Biotin carboxylase
MPOP_RS05185	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MPOP_RS05215	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MPOP_RS05220	COG2205	protein histidine kinase activity
MPOP_RS05245	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
MPOP_RS05270	COG0840	transmembrane signaling receptor activity
MPOP_RS05290	COG3237	CsbD-like
MPOP_RS05315	COG3386	PFAM SMP-30 Gluconolaconase
MPOP_RS05335	COG1999	signal sequence binding
MPOP_RS05340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MPOP_RS05370	COG0583	DNA-binding transcription factor activity
MPOP_RS05380	COG3257	ureidoglycine aminohydrolase activity
MPOP_RS05385	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
MPOP_RS05390	COG1309	transcriptional regulator
MPOP_RS05395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MPOP_RS05400	COG1335	isochorismatase
MPOP_RS05405	COG0251	oxidation-reduction process
MPOP_RS05410	COG2267	carboxylic ester hydrolase activity
MPOP_RS05415	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MPOP_RS05420	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
MPOP_RS05425	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MPOP_RS05430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MPOP_RS05435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MPOP_RS05440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MPOP_RS05450	COG2080	2 iron, 2 sulfur cluster binding
MPOP_RS05450	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MPOP_RS05455	COG0402	S-adenosylhomocysteine deaminase activity
MPOP_RS05460	COG0583	DNA-binding transcription factor activity
MPOP_RS05475	COG0402	S-adenosylhomocysteine deaminase activity
MPOP_RS05480	COG0583	DNA-binding transcription factor activity
MPOP_RS05495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MPOP_RS05520	COG2249	NAD(P)H dehydrogenase (quinone) activity
MPOP_RS05525	COG0318	PFAM AMP-dependent synthetase and ligase
MPOP_RS05570	COG3845	ABC transporter
MPOP_RS05575	COG1335	isochorismatase
MPOP_RS05590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MPOP_RS05595	COG1079	Belongs to the binding-protein-dependent transport system permease family
MPOP_RS05620	COG3845	ABC transporter
MPOP_RS05635	COG1335	isochorismatase
MPOP_RS05655	COG2233	PERMEase
MPOP_RS05665	COG2202	Pas domain
MPOP_RS05665	COG3920	Histidine kinase
MPOP_RS05680	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MPOP_RS05685	COG0830	nickel cation binding
MPOP_RS05690	COG0832	Belongs to the urease beta subunit family
MPOP_RS05690	COG0831	urea catabolic process
MPOP_RS05695	COG0804	urea catabolic process
MPOP_RS05700	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MPOP_RS05705	COG0829	nickel cation binding
MPOP_RS05740	COG4191	Histidine kinase
MPOP_RS05750	COG0517	IMP dehydrogenase activity
MPOP_RS05795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MPOP_RS05800	COG1802	Transcriptional regulator
MPOP_RS05805	COG0523	cobalamin synthesis protein
MPOP_RS05810	COG1686	Belongs to the peptidase S11 family
MPOP_RS05815	COG0602	queuosine metabolic process
MPOP_RS05820	COG0720	synthase
MPOP_RS05825	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MPOP_RS05875	COG0297	glycogen (starch) synthase activity
MPOP_RS05895	COG0642	Histidine kinase
MPOP_RS05900	COG0745	RESPONSE REGULATOR receiver
MPOP_RS05910	COG0481	GTPase activity
MPOP_RS05940	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MPOP_RS05940	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MPOP_RS05945	COG1105	Belongs to the carbohydrate kinase PfkB family
MPOP_RS05950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MPOP_RS05950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MPOP_RS05965	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MPOP_RS06000	COG1403	HNH endonuclease
MPOP_RS06005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MPOP_RS06005	COG3453	Protein conserved in bacteria
MPOP_RS06010	COG0024	Methionine aminopeptidase
MPOP_RS06015	COG2814	Major facilitator Superfamily
MPOP_RS06035	COG3246	L-lysine catabolic process to acetate
MPOP_RS06045	COG4191	Histidine kinase
MPOP_RS06050	COG1116	anion transmembrane transporter activity
MPOP_RS06055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MPOP_RS06060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MPOP_RS06065	COG0850	regulation of cytokinetic process
MPOP_RS06075	COG1217	gtp-binding protein TYPA
MPOP_RS06085	COG0850	regulation of cytokinetic process
MPOP_RS06095	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MPOP_RS06120	COG2133	pyrroloquinoline quinone binding
MPOP_RS06130	COG4221	oxidoreductase activity
MPOP_RS06135	COG0300	oxidoreductase activity
MPOP_RS06145	COG0300	oxidoreductase activity
MPOP_RS06150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MPOP_RS06155	COG0583	DNA-binding transcription factor activity
MPOP_RS06165	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MPOP_RS06175	COG0402	S-adenosylhomocysteine deaminase activity
MPOP_RS06180	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MPOP_RS06215	COG1744	ABC transporter substrate-binding protein PnrA-like
MPOP_RS06220	COG3845	ABC transporter
MPOP_RS06225	COG4603	Belongs to the binding-protein-dependent transport system permease family
MPOP_RS06230	COG1079	Belongs to the binding-protein-dependent transport system permease family
MPOP_RS06250	COG0583	DNA-binding transcription factor activity
MPOP_RS06255	COG1012	belongs to the aldehyde dehydrogenase family
MPOP_RS06270	COG2271	Major facilitator Superfamily
MPOP_RS06285	COG1012	belongs to the aldehyde dehydrogenase family
MPOP_RS06290	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MPOP_RS06310	COG0406	alpha-ribazole phosphatase activity
MPOP_RS06315	COG1260	myo-inositol-1-phosphate synthase
MPOP_RS06345	COG1032	radical SAM domain protein
MPOP_RS06350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MPOP_RS06365	COG3386	PFAM SMP-30 Gluconolaconase
MPOP_RS06370	COG3387	PFAM Glycoside hydrolase 15-related
MPOP_RS06425	COG3842	ATPase activity
MPOP_RS06435	COG1172	Belongs to the binding-protein-dependent transport system permease family
MPOP_RS06455	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MPOP_RS06460	COG2124	cytochrome p450
MPOP_RS06465	COG0864	Transcriptional regulator
MPOP_RS06495	COG2201	protein-glutamate methylesterase activity
MPOP_RS06500	COG0589	response to stress
MPOP_RS06510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MPOP_RS06515	COG4988	ABC transporter
MPOP_RS06525	COG1271	oxidase subunit
MPOP_RS06530	COG1294	oxidase, subunit
MPOP_RS06540	COG1349	DNA-binding transcription factor activity
MPOP_RS06545	COG0154	amidase activity
MPOP_RS06560	COG1215	transferase activity, transferring glycosyl groups
MPOP_RS06570	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MPOP_RS06620	COG0583	DNA-binding transcription factor activity
MPOP_RS06655	COG1028	Short-chain dehydrogenase reductase Sdr
MPOP_RS06675	COG1028	Short-chain dehydrogenase reductase Sdr
MPOP_RS06680	COG1028	Short-chain dehydrogenase reductase Sdr
MPOP_RS06735	COG2391	methyltransferase activity
MPOP_RS06780	COG4957	zinc ion binding
MPOP_RS06785	COG3750	Belongs to the UPF0335 family
MPOP_RS06910	COG1999	signal sequence binding
MPOP_RS06925	COG4423	Transcription factor
MPOP_RS06940	COG2186	Transcriptional regulator
MPOP_RS06945	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MPOP_RS06985	COG4953	penicillin-binding protein 1C
MPOP_RS06990	COG2076	Multidrug Resistance protein
MPOP_RS07030	COG3088	subunit of a heme lyase
MPOP_RS07035	COG1138	Cytochrome C-type biogenesis protein
MPOP_RS07040	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
MPOP_RS07045	COG4235	cytochrome complex assembly
MPOP_RS07060	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
MPOP_RS07090	COG3772	lysozyme
MPOP_RS07175	COG4695	Portal protein
MPOP_RS07280	COG2207	Transcriptional regulator
MPOP_RS07310	COG0714	Associated with various cellular activities
MPOP_RS07325	COG0494	nUDIX hydrolase
MPOP_RS07335	COG0617	tRNA 3'-terminal CCA addition
MPOP_RS07345	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MPOP_RS07355	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MPOP_RS07360	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MPOP_RS07365	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MPOP_RS07370	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MPOP_RS07380	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MPOP_RS07390	COG0737	Belongs to the 5'-nucleotidase family
MPOP_RS07395	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MPOP_RS07400	COG0784	Response regulator, receiver
MPOP_RS07400	COG4191	Histidine kinase
MPOP_RS07410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MPOP_RS07435	COG0494	nUDIX hydrolase
MPOP_RS07450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MPOP_RS07455	COG1598	PFAM Uncharacterised protein family UPF0150
MPOP_RS07460	COG0237	dephospho-CoA kinase activity
MPOP_RS07465	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MPOP_RS07475	COG0424	maF-like protein
MPOP_RS07485	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MPOP_RS07490	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MPOP_RS07500	COG1981	membrane
MPOP_RS07510	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MPOP_RS07515	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MPOP_RS07555	COG0314	molybdopterin synthase activity
MPOP_RS07565	COG0579	oxidoreductase
MPOP_RS07570	COG3552	Protein containing von Willebrand factor type A (VWA) domain
MPOP_RS07580	COG0714	Associated with various cellular activities
MPOP_RS07595	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MPOP_RS07610	COG0284	orotidine-5'-phosphate decarboxylase activity
MPOP_RS07625	COG1028	Short-chain dehydrogenase reductase Sdr
MPOP_RS07650	COG0288	reversible hydration of carbon dioxide
MPOP_RS07660	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MPOP_RS07675	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MPOP_RS07680	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MPOP_RS07685	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MPOP_RS07690	COG2813	Specifically methylates the guanine in position
MPOP_RS07690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MPOP_RS07715	COG0405	Gamma-glutamyltransferase
MPOP_RS07750	COG5001	Diguanylate cyclase
MPOP_RS07750	COG3300	MHYT domain
MPOP_RS07755	COG2354	Protein conserved in bacteria
MPOP_RS07760	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MPOP_RS07765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MPOP_RS07820	COG1396	sequence-specific DNA binding
MPOP_RS07835	COG5002	protein histidine kinase activity
MPOP_RS07835	COG3447	MASE1 domain protein
MPOP_RS07835	COG5001	Diguanylate cyclase
MPOP_RS07870	COG0174	glutamine synthetase
MPOP_RS07875	COG0069	glutamate synthase activity
MPOP_RS07880	COG2218	PFAM glutamate synthase alpha subunit domain protein
MPOP_RS07885	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MPOP_RS07895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MPOP_RS07905	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MPOP_RS07905	COG0446	pyridine nucleotide-disulphide oxidoreductase
MPOP_RS07915	COG0784	Response regulator, receiver
MPOP_RS07915	COG4191	Histidine kinase
MPOP_RS07920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MPOP_RS07925	COG0508	dehydrogenase complex catalyzes the overall conversion of
MPOP_RS07935	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MPOP_RS07940	COG0045	succinate-CoA ligase (ADP-forming) activity
MPOP_RS07945	COG0039	L-malate dehydrogenase activity
MPOP_RS07960	COG3093	addiction module antidote protein HigA
MPOP_RS07970	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MPOP_RS07975	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MPOP_RS07980	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MPOP_RS08000	COG0242	peptide deformylase activity
MPOP_RS08005	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MPOP_RS08010	COG0101	tRNA pseudouridine synthase activity
MPOP_RS08015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MPOP_RS08025	COG0653	protein targeting
MPOP_RS08030	COG0072	phenylalanine-tRNA ligase activity
MPOP_RS08030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MPOP_RS08045	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MPOP_RS08050	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MPOP_RS08055	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MPOP_RS08060	COG0438	transferase activity, transferring glycosyl groups
MPOP_RS08070	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MPOP_RS08075	COG0438	transferase activity, transferring glycosyl groups
MPOP_RS08090	COG0071	Belongs to the small heat shock protein (HSP20) family
MPOP_RS08130	COG5442	Flagellar protein FlaF
MPOP_RS08150	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MPOP_RS08160	COG1272	protein, Hemolysin III
MPOP_RS08165	COG1612	heme a metabolic process
MPOP_RS08195	COG1410	methionine synthase
MPOP_RS08195	COG0646	methionine synthase
MPOP_RS08205	COG2226	methyltransferase
MPOP_RS08215	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MPOP_RS08220	COG3158	transport of potassium into the cell
MPOP_RS08225	COG4774	siderophore transport
MPOP_RS08235	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MPOP_RS08240	COG0287	Prephenate dehydrogenase
MPOP_RS08280	COG0357	Ribosomal RNA small subunit methyltransferase G
MPOP_RS08285	COG0445	tRNA wobble uridine modification
MPOP_RS08295	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MPOP_RS08300	COG0495	leucyl-tRNA aminoacylation
MPOP_RS08310	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MPOP_RS08320	COG0745	RESPONSE REGULATOR receiver
MPOP_RS08330	COG2171	N-acyltransferase activity
MPOP_RS08345	COG0671	phosphoesterase, PA-phosphatase related
MPOP_RS08365	COG1253	flavin adenine dinucleotide binding
MPOP_RS08380	COG4774	siderophore transport
MPOP_RS08385	COG0028	Belongs to the TPP enzyme family
MPOP_RS08390	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MPOP_RS08410	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
MPOP_RS08425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MPOP_RS08430	COG0124	histidyl-tRNA synthetase
MPOP_RS08455	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
MPOP_RS08470	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MPOP_RS08485	COG3321	synthase
MPOP_RS08485	COG1028	Short-chain dehydrogenase reductase Sdr
MPOP_RS08485	COG0604	alcohol dehydrogenase
MPOP_RS08495	COG1250	3-hydroxyacyl-CoA dehydrogenase
MPOP_RS08500	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MPOP_RS08505	COG2086	electron transfer activity
MPOP_RS08510	COG2096	Adenosyltransferase
MPOP_RS08540	COG1984	allophanate hydrolase subunit 2
MPOP_RS08555	COG2201	protein-glutamate methylesterase activity
MPOP_RS08570	COG0784	Response regulator, receiver
MPOP_RS08570	COG0643	Histidine kinase
MPOP_RS08570	COG2198	Histidine kinase
MPOP_RS08620	COG3768	UPF0283 membrane protein
MPOP_RS08625	COG3106	COG3106 Predicted ATPase
MPOP_RS08640	COG2205	protein histidine kinase activity
MPOP_RS08640	COG5002	protein histidine kinase activity
MPOP_RS08640	COG0784	Response regulator, receiver
MPOP_RS08695	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MPOP_RS08705	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MPOP_RS08725	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MPOP_RS08730	COG0438	transferase activity, transferring glycosyl groups
MPOP_RS08740	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MPOP_RS08745	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MPOP_RS08750	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MPOP_RS08755	COG3404	Formiminotransferase-cyclodeaminase
MPOP_RS08760	COG0045	succinate-CoA ligase (ADP-forming) activity
MPOP_RS08765	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MPOP_RS08770	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MPOP_RS08785	COG0412	Dienelactone hydrolase
MPOP_RS08790	COG2154	pterin-4-alpha-carbinolamine dehydratase
MPOP_RS08825	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MPOP_RS08830	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MPOP_RS08835	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MPOP_RS08850	COG0535	radical SAM domain protein
MPOP_RS08855	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
MPOP_RS08860	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MPOP_RS08875	COG2205	protein histidine kinase activity
MPOP_RS08885	COG2218	PFAM glutamate synthase alpha subunit domain protein
MPOP_RS08890	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
MPOP_RS08895	COG1229	Formylmethanofuran dehydrogenase subunit A
MPOP_RS08900	COG1029	Formylmethanofuran dehydrogenase, subunit B
MPOP_RS08910	COG0702	epimerase
MPOP_RS08920	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
MPOP_RS08925	COG0189	ligase activity
MPOP_RS08935	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
MPOP_RS08955	COG3391	amine dehydrogenase activity
MPOP_RS09015	COG1131	(ABC) transporter
MPOP_RS09050	COG0438	transferase activity, transferring glycosyl groups
MPOP_RS09065	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MPOP_RS09070	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MPOP_RS09085	COG0606	chelatase, subunit chli
MPOP_RS09110	COG1607	acyl-coa hydrolase
MPOP_RS09120	COG0741	lytic transglycosylase activity
MPOP_RS09125	COG0243	molybdopterin cofactor binding
MPOP_RS09130	COG4172	Belongs to the ABC transporter superfamily
MPOP_RS09135	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MPOP_RS09160	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MPOP_RS09165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MPOP_RS09170	COG1562	ergosterol biosynthetic process
MPOP_RS09175	COG1562	ergosterol biosynthetic process
MPOP_RS09180	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MPOP_RS09185	COG1657	PFAM Prenyltransferase squalene oxidase
MPOP_RS09195	COG0156	8-amino-7-oxononanoate synthase activity
MPOP_RS09200	COG1028	Short-chain dehydrogenase reductase Sdr
MPOP_RS09200	COG0604	alcohol dehydrogenase
MPOP_RS09200	COG3321	synthase
MPOP_RS09205	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MPOP_RS09210	COG0438	transferase activity, transferring glycosyl groups
MPOP_RS09210	COG1216	Glycosyl transferase, family 2
MPOP_RS09235	COG4227	nucleotidyltransferase activity
MPOP_RS09525	COG4974	Belongs to the 'phage' integrase family
MPOP_RS09535	COG4303	Ethanolamine ammonia lyase large subunit
MPOP_RS09540	COG4302	ethanolamine ammonia-lyase activity
MPOP_RS09545	COG0129	dihydroxy-acid dehydratase activity
MPOP_RS09580	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MPOP_RS09595	COG1494	fructose-1,6-bisphosphatase
MPOP_RS09620	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MPOP_RS09625	COG2264	protein methyltransferase activity
MPOP_RS09630	COG0438	transferase activity, transferring glycosyl groups
MPOP_RS09640	COG0840	transmembrane signaling receptor activity
MPOP_RS09645	COG1271	oxidase subunit
MPOP_RS09670	COG0672	)-iron permease
MPOP_RS09680	COG5328	Belongs to the UPF0262 family
MPOP_RS09685	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MPOP_RS09700	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MPOP_RS09710	COG0156	8-amino-7-oxononanoate synthase activity
MPOP_RS09730	COG2824	Alkylphosphonate utilization operon protein PhnA
MPOP_RS09735	COG1234	tRNA 3'-trailer cleavage
MPOP_RS09740	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
MPOP_RS09750	COG1561	YicC-like family, N-terminal region
MPOP_RS09755	COG0194	GDP metabolic process
MPOP_RS09760	COG1132	(ABC) transporter
MPOP_RS09780	COG1376	ErfK ybiS ycfS ynhG family protein
MPOP_RS09785	COG0778	Nitroreductase
MPOP_RS09795	COG4774	siderophore transport
MPOP_RS09800	COG0800	Aldolase
MPOP_RS09805	COG0129	dihydroxy-acid dehydratase activity
MPOP_RS09840	COG0405	Gamma-glutamyltransferase
MPOP_RS09860	COG0105	UTP biosynthetic process
MPOP_RS09880	COG2879	small protein
MPOP_RS09885	COG1966	Carbon starvation protein
MPOP_RS09895	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MPOP_RS09900	COG1704	LemA family
MPOP_RS09910	COG5001	Diguanylate cyclase
MPOP_RS09915	COG0656	L-ascorbic acid biosynthetic process
MPOP_RS09920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MPOP_RS09925	COG0297	glycogen (starch) synthase activity
MPOP_RS09930	COG0366	Alpha amylase catalytic
MPOP_RS09935	COG0058	SHG alpha-glucan phosphorylase activity
MPOP_RS09955	COG5001	Diguanylate cyclase
MPOP_RS09960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MPOP_RS09965	COG0702	epimerase
MPOP_RS09970	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MPOP_RS09975	COG1733	regulation of RNA biosynthetic process
MPOP_RS09980	COG1086	Polysaccharide biosynthesis protein
MPOP_RS10035	COG1902	pentaerythritol trinitrate reductase activity
MPOP_RS10040	COG0546	phosphoglycolate phosphatase activity
MPOP_RS10060	COG0416	fatty acid biosynthetic process
MPOP_RS10065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MPOP_RS10070	COG0776	regulation of translation
MPOP_RS10090	COG2766	serine protein kinase
MPOP_RS10095	COG2718	Belongs to the UPF0229 family
MPOP_RS10100	COG2719	SpoVR family
MPOP_RS10105	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MPOP_RS10110	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MPOP_RS10115	COG0628	permease
MPOP_RS10125	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MPOP_RS10140	COG0436	Aminotransferase
MPOP_RS10155	COG0052	Belongs to the universal ribosomal protein uS2 family
MPOP_RS10160	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MPOP_RS10165	COG0528	UMP kinase activity
MPOP_RS10170	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MPOP_RS10190	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MPOP_RS10195	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MPOP_RS10200	COG0750	zinc metalloprotease
MPOP_RS10205	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MPOP_RS10215	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MPOP_RS10220	COG0233	cytoplasmic translational termination
MPOP_RS10230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MPOP_RS10235	COG1946	Acyl-CoA thioesterase
MPOP_RS10240	COG0347	Belongs to the P(II) protein family
MPOP_RS10245	COG0004	ammonium transporteR
MPOP_RS10255	COG1674	ftsk spoiiie
MPOP_RS10265	COG3920	Histidine kinase
MPOP_RS10275	COG0243	molybdopterin cofactor binding
MPOP_RS10305	COG1045	serine acetyltransferase
MPOP_RS10310	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MPOP_RS10315	COG0747	negative chemotaxis
MPOP_RS10320	COG4191	Histidine kinase
MPOP_RS10320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MPOP_RS10340	COG0784	Response regulator, receiver
MPOP_RS10340	COG3437	response regulator, receiver
MPOP_RS10385	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MPOP_RS10410	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MPOP_RS10415	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MPOP_RS10420	COG1872	DUF167
MPOP_RS10425	COG3300	MHYT domain
MPOP_RS10425	COG5001	Diguanylate cyclase
MPOP_RS10440	COG1819	glycosyl
MPOP_RS10460	COG5001	Diguanylate cyclase
MPOP_RS10470	COG3237	CsbD-like
MPOP_RS10485	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MPOP_RS10490	COG0318	PFAM AMP-dependent synthetase and ligase
MPOP_RS10520	COG1942	4-Oxalocrotonate Tautomerase
MPOP_RS10535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MPOP_RS10550	COG0583	DNA-binding transcription factor activity
MPOP_RS10555	COG0346	lactoylglutathione lyase activity
MPOP_RS10560	COG0400	carboxylic ester hydrolase activity
MPOP_RS10565	COG0456	acetyltransferase
MPOP_RS10565	COG1846	Transcriptional regulator
MPOP_RS10580	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MPOP_RS10585	COG0049	tRNA binding
MPOP_RS10590	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MPOP_RS10595	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MPOP_RS10600	COG0051	transcription antitermination factor activity, RNA binding
MPOP_RS10605	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MPOP_RS10610	COG0088	Forms part of the polypeptide exit tunnel
MPOP_RS10615	COG0089	rRNA binding
MPOP_RS10620	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MPOP_RS10625	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MPOP_RS10630	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MPOP_RS10635	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MPOP_RS10640	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MPOP_RS10645	COG0255	Belongs to the universal ribosomal protein uL29 family
MPOP_RS10650	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MPOP_RS10655	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MPOP_RS10680	COG1846	Transcriptional regulator
MPOP_RS10685	COG0203	ribosomal protein L17
MPOP_RS10690	COG0202	RNA polymerase activity
MPOP_RS10700	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MPOP_RS10705	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MPOP_RS10710	COG0563	adenylate kinase activity
MPOP_RS10715	COG0201	protein transport
MPOP_RS10720	COG0200	Binds to the 23S rRNA
MPOP_RS10725	COG1841	ribosomal large subunit assembly
MPOP_RS10730	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MPOP_RS10735	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MPOP_RS10740	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MPOP_RS10745	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MPOP_RS10750	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MPOP_RS10755	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MPOP_RS10760	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MPOP_RS10765	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MPOP_RS10785	COG3706	GGDEF domain
MPOP_RS10785	COG4251	negative regulation of phosphorylation
MPOP_RS10785	COG5001	Diguanylate cyclase
MPOP_RS10785	COG2203	Gaf domain
MPOP_RS10800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MPOP_RS10810	COG0024	Methionine aminopeptidase
MPOP_RS10815	COG2003	Belongs to the UPF0758 family
MPOP_RS10820	COG2308	Evidence 4 Homologs of previously reported genes of
MPOP_RS10865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MPOP_RS10870	COG1253	flavin adenine dinucleotide binding
MPOP_RS10890	COG4251	negative regulation of phosphorylation
MPOP_RS10890	COG3706	GGDEF domain
MPOP_RS10890	COG5001	Diguanylate cyclase
MPOP_RS10890	COG2203	Gaf domain
MPOP_RS10895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MPOP_RS10910	COG0438	transferase activity, transferring glycosyl groups
MPOP_RS10920	COG3300	MHYT domain
MPOP_RS10920	COG5001	Diguanylate cyclase
MPOP_RS10940	COG2895	sulfate adenylyltransferase (ATP) activity
MPOP_RS10945	COG0175	sulfate reduction
MPOP_RS10950	COG0175	sulfate reduction
MPOP_RS10955	COG1522	sequence-specific DNA binding
MPOP_RS10960	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MPOP_RS10965	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MPOP_RS10990	COG0629	single-stranded DNA binding
MPOP_RS10995	COG2130	NADP-dependent
MPOP_RS11010	COG3698	Phosphodiester glycosidase
MPOP_RS11015	COG1902	pentaerythritol trinitrate reductase activity
MPOP_RS11020	COG0435	Glutathione S-transferase
MPOP_RS11030	COG3118	belongs to the thioredoxin family
MPOP_RS11040	COG2835	tetraacyldisaccharide 4'-kinase activity
MPOP_RS11050	COG4191	Histidine kinase
MPOP_RS11050	COG0784	Response regulator, receiver
MPOP_RS11090	COG1752	Esterase of the alpha-beta hydrolase superfamily
MPOP_RS11095	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MPOP_RS11100	COG0302	gtp cyclohydrolase
MPOP_RS11110	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MPOP_RS11115	COG0670	Belongs to the BI1 family
MPOP_RS11125	COG0640	Transcriptional regulator
MPOP_RS11135	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MPOP_RS11140	COG0736	holo-[acyl-carrier-protein] synthase activity
MPOP_RS11145	COG0681	Belongs to the peptidase S26 family
MPOP_RS11150	COG0571	ribonuclease III activity
MPOP_RS11155	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MPOP_RS11160	COG2813	Specifically methylates the guanine in position
MPOP_RS11165	COG1187	pseudouridine synthase activity
MPOP_RS11185	COG3158	transport of potassium into the cell
MPOP_RS11195	COG0494	nUDIX hydrolase
MPOP_RS11210	COG0793	Belongs to the peptidase S41A family
MPOP_RS11220	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MPOP_RS11230	COG5001	Diguanylate cyclase
MPOP_RS11230	COG3300	MHYT domain
MPOP_RS11240	COG0137	argininosuccinate synthase activity
MPOP_RS11250	COG0546	phosphoglycolate phosphatase activity
MPOP_RS11260	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MPOP_RS11290	COG2137	regulation of response to DNA damage stimulus
MPOP_RS11295	COG1764	response to oxidative stress
MPOP_RS11305	COG1573	uracil-dna glycosylase
MPOP_RS11335	COG0625	glutathione transferase activity
MPOP_RS11345	COG0778	Nitroreductase
MPOP_RS11360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MPOP_RS11365	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MPOP_RS11375	COG1940	carbohydrate kinase activity
MPOP_RS11380	COG1301	dicarboxylic acid transport
MPOP_RS11385	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MPOP_RS11390	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MPOP_RS11400	COG0612	Peptidase, M16
MPOP_RS11405	COG0612	Peptidase, M16
MPOP_RS11410	COG0346	lactoylglutathione lyase activity
MPOP_RS11420	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MPOP_RS11470	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MPOP_RS11500	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MPOP_RS11505	COG2031	fatty acid transporter
MPOP_RS11510	COG3047	cAMP biosynthetic process
MPOP_RS11520	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MPOP_RS11525	COG0706	membrane insertase activity
MPOP_RS11530	COG0594	ribonuclease P activity
MPOP_RS11535	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MPOP_RS11545	COG0254	rRNA binding
MPOP_RS11550	COG1132	(ABC) transporter
MPOP_RS11555	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MPOP_RS11570	COG1692	metallophosphoesterase
MPOP_RS11575	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MPOP_RS11600	COG0126	phosphoglycerate kinase activity
MPOP_RS11620	COG0531	amino acid
MPOP_RS11625	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MPOP_RS11625	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MPOP_RS11630	COG0347	Belongs to the P(II) protein family
MPOP_RS11635	COG2066	Belongs to the glutaminase family
MPOP_RS11640	COG0174	glutamine synthetase
MPOP_RS11645	COG0174	glutamine synthetase
MPOP_RS11650	COG5001	Diguanylate cyclase
MPOP_RS11650	COG3300	MHYT domain
MPOP_RS11655	COG0431	NADPH-dependent FMN reductase
MPOP_RS11665	COG0557	exoribonuclease II activity
MPOP_RS11690	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MPOP_RS11700	COG1968	undecaprenyl-diphosphatase activity
MPOP_RS11730	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
MPOP_RS11735	COG1088	dTDP-glucose 4,6-dehydratase activity
MPOP_RS11740	COG1091	dTDP-4-dehydrorhamnose reductase activity
MPOP_RS11745	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MPOP_RS11750	COG3161	chorismate lyase activity
MPOP_RS11760	COG0653	protein targeting
MPOP_RS11820	COG2132	Multicopper oxidase
MPOP_RS11830	COG0544	peptidyl-prolyl cis-trans isomerase activity
MPOP_RS11835	COG0740	serine-type endopeptidase activity
MPOP_RS11840	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MPOP_RS11845	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MPOP_RS11865	COG2890	protein-(glutamine-N5) methyltransferase activity
MPOP_RS11875	COG3665	Urea carboxylase-associated protein
MPOP_RS11880	COG1297	OPT oligopeptide transporter protein
MPOP_RS11945	COG3328	transposase activity
MPOP_RS11960	COG1295	ribonuclease BN
MPOP_RS11970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MPOP_RS11970	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MPOP_RS11975	COG1515	deoxyribonuclease V activity
MPOP_RS11980	COG0012	GTP binding
MPOP_RS11985	COG0193	aminoacyl-tRNA hydrolase activity
MPOP_RS11990	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MPOP_RS12015	COG4964	Belongs to the GSP D family
MPOP_RS12050	COG0477	Major facilitator Superfamily
MPOP_RS12055	COG1764	response to oxidative stress
MPOP_RS12060	COG1832	CoA-binding protein
MPOP_RS12075	COG2203	Gaf domain
MPOP_RS12075	COG5001	Diguanylate cyclase
MPOP_RS12075	COG4251	negative regulation of phosphorylation
MPOP_RS12075	COG3706	GGDEF domain
MPOP_RS12115	COG1137	ATPase activity
MPOP_RS12120	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MPOP_RS12125	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MPOP_RS12130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MPOP_RS12145	COG0588	phosphoglycerate mutase activity
MPOP_RS12165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MPOP_RS12175	COG4974	Belongs to the 'phage' integrase family
MPOP_RS12180	COG3706	GGDEF domain
MPOP_RS12190	COG4239	(ABC) transporter, permease
MPOP_RS12200	COG0436	Aminotransferase
MPOP_RS12215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MPOP_RS12220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MPOP_RS12235	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MPOP_RS12240	COG0473	3-isopropylmalate dehydrogenase activity
MPOP_RS12265	COG0142	geranyltranstransferase activity
MPOP_RS12270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MPOP_RS12275	COG0415	Belongs to the DNA photolyase family
MPOP_RS12280	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MPOP_RS12300	COG1368	sulfuric ester hydrolase activity
MPOP_RS12320	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MPOP_RS12330	COG0723	plastoquinol--plastocyanin reductase activity
MPOP_RS12335	COG2857	Cytochrome c1
MPOP_RS12335	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MPOP_RS12340	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MPOP_RS12340	COG2857	Cytochrome c1
MPOP_RS12350	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MPOP_RS12365	COG0131	Imidazoleglycerol-phosphate dehydratase
MPOP_RS12375	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MPOP_RS12380	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MPOP_RS12390	COG0107	imidazoleglycerol-phosphate synthase activity
MPOP_RS12395	COG0140	phosphoribosyl-ATP diphosphatase activity
MPOP_RS12400	COG1072	(Pantothenic acid kinase))
MPOP_RS12425	COG1388	LysM domain
MPOP_RS12425	COG1376	ErfK ybiS ycfS ynhG family protein
MPOP_RS12440	COG2205	protein histidine kinase activity
MPOP_RS12445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MPOP_RS12450	COG3162	membrane
MPOP_RS12465	COG0138	bifunctional purine biosynthesis protein purh
MPOP_RS12475	COG2897	thiosulfate sulfurtransferase activity
MPOP_RS12490	COG0513	Belongs to the DEAD box helicase family
MPOP_RS12510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MPOP_RS12540	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MPOP_RS12575	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MPOP_RS12600	COG0675	Transposase, IS605 OrfB family
MPOP_RS12640	COG1937	Protein conserved in bacteria
MPOP_RS12650	COG0789	Transcriptional regulator
MPOP_RS12655	COG2217	Heavy metal translocating P-type atpase
MPOP_RS12675	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
MPOP_RS12680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MPOP_RS12685	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MPOP_RS12690	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MPOP_RS12705	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MPOP_RS12715	COG1007	ATP synthesis coupled electron transport
MPOP_RS12755	COG0675	Transposase, IS605 OrfB family
MPOP_RS12805	COG0675	Transposase, IS605 OrfB family
MPOP_RS12820	COG1595	DNA-templated transcription, initiation
MPOP_RS12860	COG2132	Multicopper oxidase
MPOP_RS12905	COG0419	ATPase involved in DNA repair
MPOP_RS12920	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MPOP_RS12995	COG1970	mechanosensitive ion channel activity
MPOP_RS13010	COG0436	Aminotransferase
MPOP_RS13025	COG0745	RESPONSE REGULATOR receiver
MPOP_RS13030	COG1846	Transcriptional regulator
MPOP_RS13035	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MPOP_RS13050	COG0534	Mate efflux family protein
MPOP_RS13055	COG0475	glutathione-regulated potassium exporter activity
MPOP_RS13055	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MPOP_RS13060	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MPOP_RS13065	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MPOP_RS13075	COG1678	Uncharacterized ACR, COG1678
MPOP_RS13085	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MPOP_RS13090	COG2378	regulation of single-species biofilm formation
MPOP_RS13095	COG0625	glutathione transferase activity
MPOP_RS13100	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MPOP_RS13120	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MPOP_RS13125	COG1684	flagellar biosynthetic protein fliR
MPOP_RS13130	COG1987	bacterial-type flagellum assembly
MPOP_RS13135	COG1677	Flagellar hook-basal body complex protein FliE
MPOP_RS13140	COG1558	bacterial-type flagellum-dependent cell motility
MPOP_RS13155	COG0579	oxidoreductase
MPOP_RS13165	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MPOP_RS13175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MPOP_RS13180	COG0247	lactate metabolic process
MPOP_RS13185	COG1139	Iron-sulfur cluster binding protein
MPOP_RS13200	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MPOP_RS13205	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MPOP_RS13225	COG1132	(ABC) transporter
MPOP_RS13485	COG0305	Participates in initiation and elongation during chromosome replication
MPOP_RS13570	COG1396	sequence-specific DNA binding
MPOP_RS13695	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MPOP_RS13700	COG0424	maF-like protein
MPOP_RS13715	COG4774	siderophore transport
MPOP_RS13730	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MPOP_RS13735	COG4133	protoheme IX ABC transporter activity
MPOP_RS13740	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MPOP_RS13745	COG2329	Antibiotic biosynthesis monooxygenase
MPOP_RS13750	COG0625	glutathione transferase activity
MPOP_RS13755	COG1252	NADH dehydrogenase
MPOP_RS13770	COG0840	transmembrane signaling receptor activity
MPOP_RS13780	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MPOP_RS13790	COG1376	ErfK ybiS ycfS ynhG family protein
MPOP_RS13790	COG1388	LysM domain
MPOP_RS13810	COG2084	Dehydrogenase
MPOP_RS13815	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MPOP_RS13820	COG0560	Phosphoserine phosphatase
MPOP_RS13830	COG0330	HflC and HflK could
MPOP_RS13835	COG0330	HflC and HflK could
MPOP_RS13860	COG2124	cytochrome p450
MPOP_RS13865	COG0114	fumarate hydratase activity
MPOP_RS13885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MPOP_RS13890	COG0586	Pfam SNARE associated Golgi protein
MPOP_RS13895	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
MPOP_RS13900	COG0384	phenazine biosynthesis protein PhzF
MPOP_RS13920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MPOP_RS13935	COG4948	Mandelate Racemase Muconate Lactonizing
MPOP_RS13960	COG0673	inositol 2-dehydrogenase activity
MPOP_RS13975	COG0438	transferase activity, transferring glycosyl groups
MPOP_RS13990	COG0392	lysyltransferase activity
MPOP_RS13995	COG5002	protein histidine kinase activity
MPOP_RS14010	COG0789	Transcriptional regulator
MPOP_RS14015	COG1473	amidohydrolase
MPOP_RS14025	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MPOP_RS14030	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MPOP_RS14035	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MPOP_RS14050	COG0779	Required for maturation of 30S ribosomal subunits
MPOP_RS14055	COG0110	maltose O-acetyltransferase activity
MPOP_RS14060	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MPOP_RS14075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MPOP_RS14085	COG0523	cobalamin synthesis protein
MPOP_RS14090	COG1309	transcriptional regulator
MPOP_RS14100	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MPOP_RS14110	COG0366	Alpha amylase catalytic
MPOP_RS14115	COG0366	Alpha amylase catalytic
MPOP_RS14120	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MPOP_RS14125	COG1742	UPF0060 membrane protein
MPOP_RS14150	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MPOP_RS14155	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MPOP_RS14160	COG0564	pseudouridine synthase activity
MPOP_RS14165	COG0552	protein localization to endoplasmic reticulum
MPOP_RS14185	COG0142	geranyltranstransferase activity
MPOP_RS14190	COG0500	methyltransferase
MPOP_RS14195	COG1063	alcohol dehydrogenase
MPOP_RS14200	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
MPOP_RS14205	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
MPOP_RS14210	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
MPOP_RS14245	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
MPOP_RS14250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MPOP_RS14255	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MPOP_RS14260	COG0457	Tetratricopeptide repeat
MPOP_RS14265	COG0596	Alpha beta hydrolase
MPOP_RS14270	COG0469	pyruvate kinase activity
MPOP_RS14300	COG3750	Belongs to the UPF0335 family
MPOP_RS14305	COG0625	glutathione transferase activity
MPOP_RS14320	COG2204	response regulator
MPOP_RS14340	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MPOP_RS14405	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
MPOP_RS14410	COG3604	Transcriptional regulator
MPOP_RS14420	COG1858	cytochrome C peroxidase
MPOP_RS14430	COG5001	Diguanylate cyclase
MPOP_RS14435	COG3546	catalase activity
MPOP_RS14460	COG0038	chloride channel
MPOP_RS14470	COG2877	3-deoxy-8-phosphooctulonate synthase activity
MPOP_RS14480	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MPOP_RS14485	COG0148	phosphopyruvate hydratase activity
MPOP_RS14490	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MPOP_RS14495	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MPOP_RS14500	COG0022	dehydrogenase e1 component
MPOP_RS14500	COG0508	dehydrogenase complex catalyzes the overall conversion of
MPOP_RS14510	COG0508	dehydrogenase complex catalyzes the overall conversion of
MPOP_RS14515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MPOP_RS14565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MPOP_RS14570	COG2867	negative regulation of translational initiation
MPOP_RS14580	COG2423	ornithine cyclodeaminase activity
MPOP_RS14590	COG3549	Plasmid maintenance system killer
MPOP_RS14600	COG5265	(ABC) transporter
MPOP_RS14605	COG2080	2 iron, 2 sulfur cluster binding
MPOP_RS14610	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MPOP_RS14615	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MPOP_RS14620	COG1546	Belongs to the CinA family
MPOP_RS14620	COG1058	Belongs to the CinA family
MPOP_RS14625	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MPOP_RS14625	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MPOP_RS14630	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MPOP_RS14640	COG2204	response regulator
MPOP_RS14645	COG1061	Type III restriction enzyme res subunit
MPOP_RS14650	COG5000	phosphorelay sensor kinase activity
MPOP_RS14655	COG2204	response regulator
MPOP_RS14660	COG1923	regulation of RNA biosynthetic process
MPOP_RS14665	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MPOP_RS14670	COG0659	secondary active sulfate transmembrane transporter activity
MPOP_RS14710	COG4957	zinc ion binding
MPOP_RS14770	COG0303	'Molybdopterin
MPOP_RS14775	COG1763	Mo-molybdopterin cofactor biosynthetic process
MPOP_RS14815	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
MPOP_RS14820	COG2943	transferase activity, transferring hexosyl groups
MPOP_RS14835	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
MPOP_RS14840	COG0277	FAD linked oxidase domain protein
MPOP_RS14845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MPOP_RS14850	COG2204	response regulator
MPOP_RS14855	COG0037	tRNA processing
MPOP_RS14855	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MPOP_RS14865	COG2884	Cell division ATP-binding protein ftsE
MPOP_RS14885	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MPOP_RS14890	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MPOP_RS14900	COG0799	negative regulation of ribosome biogenesis
MPOP_RS14925	COG1132	(ABC) transporter
MPOP_RS14935	COG0803	Belongs to the bacterial solute-binding protein 9 family
MPOP_RS14940	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MPOP_RS14945	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MPOP_RS14960	COG1376	ErfK ybiS ycfS ynhG family protein
MPOP_RS14970	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MPOP_RS14975	COG1496	oxidoreductase activity
MPOP_RS14985	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MPOP_RS14990	COG1285	pathogenesis
MPOP_RS14995	COG0033	Phosphoglucomutase
MPOP_RS15015	COG0574	Belongs to the PEP-utilizing enzyme family
MPOP_RS15015	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MPOP_RS15020	COG1376	ErfK ybiS ycfS ynhG family protein
MPOP_RS15025	COG0346	lactoylglutathione lyase activity
MPOP_RS15035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MPOP_RS15035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MPOP_RS15060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MPOP_RS15085	COG0784	Response regulator, receiver
MPOP_RS15100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MPOP_RS15110	COG1408	metallophosphoesterase
MPOP_RS15135	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MPOP_RS15145	COG1686	Belongs to the peptidase S11 family
MPOP_RS15210	COG2176	DNA-directed DNA polymerase activity
MPOP_RS15215	COG1074	ATP-dependent DNA helicase activity
MPOP_RS15240	COG1475	DNA binding
MPOP_RS15285	COG5489	Protein of unknown function (DUF736)
MPOP_RS15315	COG1192	Involved in chromosome partitioning
MPOP_RS15330	COG4959	Type IV secretory pathway protease TraF
MPOP_RS15360	COG4962	Type ii secretion system protein e
MPOP_RS15375	COG3451	type IV secretory pathway VirB4
MPOP_RS15390	COG3846	protein secretion by the type IV secretion system
MPOP_RS15405	COG2948	multi-organism process
MPOP_RS15415	COG0583	DNA-binding transcription factor activity
MPOP_RS15420	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MPOP_RS15485	COG0582	viral genome integration into host DNA
MPOP_RS15490	COG0519	Catalyzes the synthesis of GMP from XMP
MPOP_RS15490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MPOP_RS15500	COG2755	lipolytic protein G-D-S-L family
MPOP_RS15500	COG0657	acetylesterase activity
MPOP_RS15505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MPOP_RS15505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MPOP_RS15510	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MPOP_RS15535	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MPOP_RS15540	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MPOP_RS15550	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MPOP_RS15565	COG1181	Belongs to the D-alanine--D-alanine ligase family
MPOP_RS15570	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MPOP_RS15575	COG0849	cell division
MPOP_RS15580	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MPOP_RS15590	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MPOP_RS15600	COG0497	DNA recombination
MPOP_RS15620	COG0243	molybdopterin cofactor binding
MPOP_RS15630	COG0443	Heat shock 70 kDa protein
MPOP_RS15635	COG0484	heat shock protein binding
MPOP_RS15640	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MPOP_RS15665	COG0295	cytidine deaminase activity
MPOP_RS15675	COG1663	tetraacyldisaccharide 4'-kinase activity
MPOP_RS15680	COG1519	Transferase
MPOP_RS15700	COG1278	Cold shock
MPOP_RS15710	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MPOP_RS15720	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MPOP_RS15730	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
MPOP_RS15755	COG0739	heme binding
MPOP_RS15755	COG0741	lytic transglycosylase activity
MPOP_RS15755	COG1196	nuclear chromosome segregation
MPOP_RS15760	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MPOP_RS15775	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MPOP_RS15780	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MPOP_RS15790	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MPOP_RS15795	COG3657	addiction module killer protein
MPOP_RS15800	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MPOP_RS15805	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MPOP_RS15805	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MPOP_RS15815	COG0123	including yeast histone deacetylase and acetoin utilization protein
MPOP_RS15825	COG4770	biotin carboxylase activity
MPOP_RS15840	COG2116	formate transmembrane transporter activity
MPOP_RS15845	COG1254	Belongs to the acylphosphatase family
MPOP_RS15870	COG0625	glutathione transferase activity
MPOP_RS15875	COG1509	lysine 2,3-aminomutase activity
MPOP_RS15880	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
MPOP_RS15885	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MPOP_RS15905	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
MPOP_RS15915	COG1233	COG1233 Phytoene dehydrogenase and related
MPOP_RS15920	COG1562	ergosterol biosynthetic process
MPOP_RS15925	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MPOP_RS15930	COG0830	nickel cation binding
MPOP_RS15935	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MPOP_RS15940	COG0804	urea catabolic process
MPOP_RS15950	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MPOP_RS15955	COG0831	urea catabolic process
MPOP_RS15955	COG0832	Belongs to the urease beta subunit family
MPOP_RS15960	COG0829	nickel cation binding
MPOP_RS15965	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MPOP_RS15990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MPOP_RS15995	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MPOP_RS16025	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MPOP_RS16035	COG2900	Belongs to the SlyX family
MPOP_RS16055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MPOP_RS16085	COG1696	Membrane protein involved in D-alanine export
MPOP_RS16100	COG1706	bacterial-type flagellum-dependent cell motility
MPOP_RS16125	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
MPOP_RS16130	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
MPOP_RS16135	COG4786	Flagellar basal body rod
MPOP_RS16140	COG4786	Flagellar basal body rod
MPOP_RS16165	COG2442	InterPro IPR007367
MPOP_RS16170	COG4634	DNA integration
MPOP_RS16175	COG0386	Belongs to the glutathione peroxidase family
MPOP_RS16185	COG2951	lytic endotransglycosylase activity
MPOP_RS16190	COG2249	NAD(P)H dehydrogenase (quinone) activity
MPOP_RS16200	COG1301	dicarboxylic acid transport
MPOP_RS16205	COG4191	Histidine kinase
MPOP_RS16210	COG2204	response regulator
MPOP_RS16215	COG3706	GGDEF domain
MPOP_RS16220	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MPOP_RS16250	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MPOP_RS16260	COG0343	queuine tRNA-ribosyltransferase activity
MPOP_RS16295	COG2954	triphosphatase activity
MPOP_RS16325	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
MPOP_RS16340	COG0436	Aminotransferase
MPOP_RS16355	COG4651	solute:proton antiporter activity
MPOP_RS16355	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MPOP_RS16380	COG0752	glycyl-tRNA synthetase alpha subunit
MPOP_RS16390	COG1309	transcriptional regulator
MPOP_RS16410	COG2890	protein-(glutamine-N5) methyltransferase activity
MPOP_RS16420	COG0142	geranyltranstransferase activity
MPOP_RS16425	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MPOP_RS16470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MPOP_RS16495	COG0187	DNA topoisomerase II activity
MPOP_RS16510	COG1132	(ABC) transporter
MPOP_RS16540	COG1028	Short-chain dehydrogenase reductase Sdr
MPOP_RS16545	COG2814	Major facilitator Superfamily
MPOP_RS16550	COG2267	carboxylic ester hydrolase activity
MPOP_RS16560	COG0625	glutathione transferase activity
MPOP_RS16580	COG0590	tRNA wobble adenosine to inosine editing
MPOP_RS16600	COG4191	Histidine kinase
MPOP_RS16600	COG0784	Response regulator, receiver
MPOP_RS16610	COG0538	isocitrate dehydrogenase activity
MPOP_RS16655	COG0247	lactate metabolic process
MPOP_RS16665	COG0657	acetylesterase activity
MPOP_RS16670	COG1201	RNA secondary structure unwinding
MPOP_RS16690	COG5487	UPF0391 membrane protein
MPOP_RS16695	COG4221	oxidoreductase activity
MPOP_RS16700	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MPOP_RS16705	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MPOP_RS16710	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MPOP_RS16715	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MPOP_RS16715	COG0546	phosphoglycolate phosphatase activity
MPOP_RS16735	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MPOP_RS16735	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MPOP_RS16740	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MPOP_RS16750	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MPOP_RS16755	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MPOP_RS16760	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MPOP_RS16770	COG0356	it plays a direct role in the translocation of protons across the membrane
MPOP_RS16780	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MPOP_RS16800	COG2189	Belongs to the N(4) N(6)-methyltransferase family
MPOP_RS16805	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MPOP_RS16815	COG0488	(ABC) transporter
MPOP_RS16845	COG0741	lytic transglycosylase activity
MPOP_RS16850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MPOP_RS16855	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MPOP_RS16865	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MPOP_RS16880	COG1758	RNA polymerase activity
MPOP_RS16885	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MPOP_RS16910	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MPOP_RS16915	COG1702	phosphate starvation-inducible protein PhoH
MPOP_RS16920	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MPOP_RS16925	COG1253	flavin adenine dinucleotide binding
MPOP_RS16930	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MPOP_RS16940	COG0753	catalase activity
MPOP_RS16950	COG3180	Ammonia monooxygenase
MPOP_RS16975	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MPOP_RS16980	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MPOP_RS16985	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
MPOP_RS17000	COG0243	molybdopterin cofactor binding
MPOP_RS17005	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MPOP_RS17005	COG1648	precorrin-2 dehydrogenase activity
MPOP_RS17010	COG1999	signal sequence binding
MPOP_RS17065	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MPOP_RS17065	COG4106	trans-aconitate 2-methyltransferase activity
MPOP_RS17075	COG1793	dna ligase
MPOP_RS17080	COG0432	Pfam Uncharacterised protein family UPF0047
MPOP_RS17100	COG1024	Enoyl-CoA hydratase
MPOP_RS17100	COG1250	3-hydroxyacyl-CoA dehydrogenase
MPOP_RS17115	COG0183	Belongs to the thiolase family
MPOP_RS17120	COG1960	acyl-CoA dehydrogenase activity
MPOP_RS17145	COG0671	phosphoesterase, PA-phosphatase related
MPOP_RS17150	COG0673	inositol 2-dehydrogenase activity
MPOP_RS17155	COG0612	Peptidase, M16
MPOP_RS17170	COG3346	SURF1 family
MPOP_RS17185	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
MPOP_RS17195	COG0109	protoheme IX farnesyltransferase activity
MPOP_RS17200	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MPOP_RS17210	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MPOP_RS17220	COG0067	glutamate synthase
MPOP_RS17220	COG0070	glutamate synthase
MPOP_RS17220	COG0069	glutamate synthase activity
MPOP_RS17245	COG4585	Histidine kinase
MPOP_RS17260	COG2951	lytic endotransglycosylase activity
MPOP_RS17270	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MPOP_RS17290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MPOP_RS17300	COG0784	Response regulator, receiver
MPOP_RS17300	COG4191	Histidine kinase
MPOP_RS17305	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MPOP_RS17310	COG2862	Uncharacterized protein family, UPF0114
MPOP_RS17345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MPOP_RS17350	COG0165	Argininosuccinate lyase
MPOP_RS17370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MPOP_RS17390	COG0728	peptidoglycan biosynthetic process
MPOP_RS17395	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MPOP_RS17405	COG3920	Histidine kinase
MPOP_RS17420	COG4783	chaperone-mediated protein folding
MPOP_RS17430	COG1396	sequence-specific DNA binding
MPOP_RS17435	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MPOP_RS17440	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MPOP_RS17445	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MPOP_RS17450	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MPOP_RS17455	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
MPOP_RS17465	COG0540	Belongs to the ATCase OTCase family
MPOP_RS17475	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MPOP_RS17480	COG0758	DNA mediated transformation
MPOP_RS17510	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MPOP_RS17515	COG0154	amidase activity
MPOP_RS17545	COG1376	ErfK ybiS ycfS ynhG family protein
MPOP_RS17560	COG0438	transferase activity, transferring glycosyl groups
MPOP_RS17570	COG1596	polysaccharide export
MPOP_RS17590	COG0489	protein tyrosine kinase activity
MPOP_RS17605	COG0110	maltose O-acetyltransferase activity
MPOP_RS17650	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
MPOP_RS17650	COG0662	Cupin 2, conserved barrel domain protein
MPOP_RS17660	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MPOP_RS17710	COG1309	transcriptional regulator
MPOP_RS17715	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MPOP_RS17735	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MPOP_RS17745	COG0411	ABC transporter
MPOP_RS17765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MPOP_RS17765	COG2205	protein histidine kinase activity
MPOP_RS17815	COG0316	Belongs to the HesB IscA family
MPOP_RS17820	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MPOP_RS17850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MPOP_RS17855	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MPOP_RS17860	COG0805	protein transport
MPOP_RS17880	COG2814	Major facilitator Superfamily
MPOP_RS17890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MPOP_RS17895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MPOP_RS17900	COG1116	anion transmembrane transporter activity
MPOP_RS17910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MPOP_RS17915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MPOP_RS17960	COG1028	Short-chain dehydrogenase reductase Sdr
MPOP_RS17965	COG2814	Major facilitator Superfamily
MPOP_RS17975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MPOP_RS17980	COG1012	belongs to the aldehyde dehydrogenase family
MPOP_RS18005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MPOP_RS18015	COG2259	Doxx family
MPOP_RS18020	COG0477	Major facilitator Superfamily
MPOP_RS18030	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MPOP_RS18035	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MPOP_RS18060	COG1233	COG1233 Phytoene dehydrogenase and related
MPOP_RS18075	COG1131	(ABC) transporter
MPOP_RS18110	COG2030	dehydratase
MPOP_RS18135	COG0625	glutathione transferase activity
MPOP_RS18170	COG3394	polysaccharide catabolic process
MPOP_RS18185	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MPOP_RS18190	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MPOP_RS18200	COG3265	gluconokinase activity
MPOP_RS18215	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MPOP_RS18245	COG2309	aminopeptidase activity
MPOP_RS18255	COG0277	FAD linked oxidase domain protein
MPOP_RS18265	COG0494	nUDIX hydrolase
MPOP_RS18290	COG0071	Belongs to the small heat shock protein (HSP20) family
MPOP_RS18295	COG0071	Belongs to the small heat shock protein (HSP20) family
MPOP_RS18365	COG5002	protein histidine kinase activity
MPOP_RS18375	COG2223	nitrite transmembrane transporter activity
MPOP_RS18390	COG1858	cytochrome C peroxidase
MPOP_RS18395	COG0583	DNA-binding transcription factor activity
MPOP_RS18430	COG0303	'Molybdopterin
MPOP_RS18440	COG0725	ABC transporter, periplasmic molybdate-binding protein
MPOP_RS18445	COG4149	molybdate abc transporter
MPOP_RS18450	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MPOP_RS18455	COG3585	molybdate ion transport
MPOP_RS18465	COG3328	transposase activity
MPOP_RS18490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MPOP_RS18515	COG0071	Belongs to the small heat shock protein (HSP20) family
MPOP_RS18520	COG0071	Belongs to the small heat shock protein (HSP20) family
MPOP_RS18530	COG3118	belongs to the thioredoxin family
MPOP_RS18535	COG3920	Histidine kinase
MPOP_RS18615	COG2197	response regulator
MPOP_RS18630	COG1994	Peptidase M50
MPOP_RS18640	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MPOP_RS18660	COG0484	heat shock protein binding
MPOP_RS18685	COG1396	sequence-specific DNA binding
MPOP_RS18715	COG0559	Belongs to the binding-protein-dependent transport system permease family
MPOP_RS18730	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MPOP_RS18735	COG0154	amidase activity
MPOP_RS18745	COG1116	anion transmembrane transporter activity
MPOP_RS18745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MPOP_RS18760	COG0583	DNA-binding transcription factor activity
MPOP_RS18765	COG3328	transposase activity
MPOP_RS18855	COG4191	Histidine kinase
MPOP_RS18855	COG0784	Response regulator, receiver
MPOP_RS18875	COG4774	siderophore transport
MPOP_RS18890	COG1120	ATPase activity
MPOP_RS18895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MPOP_RS18905	COG4206	TonB-dependent receptor
MPOP_RS18925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MPOP_RS18930	COG4172	Belongs to the ABC transporter superfamily
MPOP_RS18935	COG0625	glutathione transferase activity
MPOP_RS19005	COG2197	response regulator
MPOP_RS19045	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MPOP_RS19055	COG2963	transposase activity
MPOP_RS19090	COG2442	InterPro IPR007367
MPOP_RS19120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MPOP_RS19180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MPOP_RS19280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MPOP_RS19290	COG4566	intracellular signal transduction
MPOP_RS19295	COG4191	Histidine kinase
MPOP_RS19335	COG4770	biotin carboxylase activity
MPOP_RS19340	COG3665	Urea carboxylase-associated protein
MPOP_RS19345	COG3665	Urea carboxylase-associated protein
MPOP_RS19365	COG1116	anion transmembrane transporter activity
MPOP_RS19370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MPOP_RS19415	COG4149	molybdate abc transporter
MPOP_RS19425	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MPOP_RS19440	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
MPOP_RS19450	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MPOP_RS19455	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MPOP_RS19465	COG0659	secondary active sulfate transmembrane transporter activity
MPOP_RS19470	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
MPOP_RS19490	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MPOP_RS19520	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MPOP_RS19530	COG0318	PFAM AMP-dependent synthetase and ligase
MPOP_RS19555	COG0436	Aminotransferase
MPOP_RS19565	COG1530	ribonuclease E activity
MPOP_RS19565	COG1530	ribonuclease E activity
MPOP_RS19575	COG0860	N-Acetylmuramoyl-L-alanine amidase
MPOP_RS19580	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MPOP_RS19595	COG2080	2 iron, 2 sulfur cluster binding
MPOP_RS19600	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MPOP_RS19605	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MPOP_RS19615	COG2252	PERMEase
MPOP_RS19625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MPOP_RS19640	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
MPOP_RS19660	COG3328	transposase activity
MPOP_RS19730	COG3750	Belongs to the UPF0335 family
MPOP_RS19760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MPOP_RS19770	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MPOP_RS19770	COG0446	pyridine nucleotide-disulphide oxidoreductase
MPOP_RS19780	COG1760	l-serine dehydratase
MPOP_RS19805	COG0247	lactate metabolic process
MPOP_RS19805	COG2181	nitrate reductase activity
MPOP_RS19810	COG1902	pentaerythritol trinitrate reductase activity
MPOP_RS19810	COG0446	pyridine nucleotide-disulphide oxidoreductase
MPOP_RS19820	COG4638	Rieske (2fe-2S)
MPOP_RS19840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MPOP_RS19845	COG1349	DNA-binding transcription factor activity
MPOP_RS19850	COG4172	Belongs to the ABC transporter superfamily
MPOP_RS19860	COG0601	transmembrane transport
MPOP_RS19870	COG4774	siderophore transport
MPOP_RS19900	COG1082	Xylose isomerase domain protein TIM barrel
MPOP_RS19910	COG1247	-acetyltransferase
MPOP_RS19960	COG3328	transposase activity
MPOP_RS19970	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MPOP_RS19990	COG2030	dehydratase
MPOP_RS20070	COG0798	PFAM Bile acid sodium symporter
MPOP_RS20090	COG0431	NADPH-dependent FMN reductase
MPOP_RS20095	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MPOP_RS20145	COG3328	transposase activity
MPOP_RS20155	COG2217	Heavy metal translocating P-type atpase
MPOP_RS20160	COG0789	Transcriptional regulator
MPOP_RS20285	COG0642	Histidine kinase
MPOP_RS20310	COG0671	phosphoesterase, PA-phosphatase related
MPOP_RS20315	COG4191	Histidine kinase
MPOP_RS20315	COG0784	Response regulator, receiver
MPOP_RS20345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MPOP_RS20350	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MPOP_RS20370	COG0789	Transcriptional regulator
MPOP_RS20380	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MPOP_RS20385	COG3034	peptidoglycan biosynthetic process
MPOP_RS20390	COG0785	Cytochrome C biogenesis protein
MPOP_RS20395	COG1742	UPF0060 membrane protein
MPOP_RS20490	COG0640	Transcriptional regulator
MPOP_RS20495	COG0642	Histidine kinase
MPOP_RS20515	COG1376	ErfK ybiS ycfS ynhG family protein
MPOP_RS20515	COG1388	LysM domain
MPOP_RS20535	COG0730	response to heat
MPOP_RS20560	COG0640	Transcriptional regulator
MPOP_RS20595	COG0737	Belongs to the 5'-nucleotidase family
MPOP_RS20690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MPOP_RS20695	COG1309	transcriptional regulator
MPOP_RS20700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MPOP_RS20705	COG3328	transposase activity
MPOP_RS20720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MPOP_RS20760	COG1032	radical SAM domain protein
MPOP_RS20775	COG4191	Histidine kinase
MPOP_RS20775	COG0784	Response regulator, receiver
MPOP_RS20795	COG2010	Cytochrome c
MPOP_RS20795	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MPOP_RS20815	COG1414	Transcriptional regulator
MPOP_RS20830	COG3962	Belongs to the TPP enzyme family
MPOP_RS20835	COG4948	Mandelate Racemase Muconate Lactonizing
MPOP_RS20840	COG1028	Short-chain dehydrogenase reductase Sdr
MPOP_RS20845	COG2814	Major facilitator Superfamily
MPOP_RS20865	COG0583	DNA-binding transcription factor activity
MPOP_RS20890	COG1120	ATPase activity
MPOP_RS20895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MPOP_RS20900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MPOP_RS20910	COG3328	transposase activity
MPOP_RS20935	COG4774	siderophore transport
MPOP_RS21015	COG1088	dTDP-glucose 4,6-dehydratase activity
MPOP_RS21020	COG1091	dTDP-4-dehydrorhamnose reductase activity
MPOP_RS21025	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MPOP_RS21050	COG1028	Short-chain dehydrogenase reductase Sdr
MPOP_RS21055	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MPOP_RS21070	COG1116	anion transmembrane transporter activity
MPOP_RS21075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MPOP_RS21115	COG1321	iron dependent repressor
MPOP_RS21120	COG1914	H( )-stimulated, divalent metal cation uptake system
MPOP_RS21130	COG0471	metal ion transport
MPOP_RS21190	COG1024	Enoyl-CoA hydratase
MPOP_RS21200	COG1028	Short-chain dehydrogenase reductase Sdr
MPOP_RS21205	COG0598	Magnesium transport protein CorA
MPOP_RS21210	COG3685	Protein conserved in bacteria
MPOP_RS21235	COG0596	Alpha beta hydrolase
MPOP_RS21240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MPOP_RS21245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MPOP_RS21250	COG1120	ATPase activity
MPOP_RS21255	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MPOP_RS21290	COG0667	Aldo Keto reductase
MPOP_RS21310	COG1335	isochorismatase
MPOP_RS21320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MPOP_RS21335	COG4989	oxidoreductase activity
MPOP_RS21345	COG0742	ribosomal rna small subunit methyltransferase
MPOP_RS21360	COG5001	Diguanylate cyclase
MPOP_RS21365	COG0596	Alpha beta hydrolase
MPOP_RS21375	COG0590	tRNA wobble adenosine to inosine editing
MPOP_RS21380	COG0151	Belongs to the GarS family
MPOP_RS21395	COG1570	exodeoxyribonuclease VII activity
MPOP_RS21410	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MPOP_RS21415	COG0604	alcohol dehydrogenase
MPOP_RS21440	COG0583	DNA-binding transcription factor activity
MPOP_RS21475	COG1079	Belongs to the binding-protein-dependent transport system permease family
MPOP_RS21485	COG3845	ABC transporter
MPOP_RS21520	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MPOP_RS21525	COG0840	transmembrane signaling receptor activity
MPOP_RS21535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MPOP_RS21585	COG3920	Histidine kinase
MPOP_RS21605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MPOP_RS21625	COG1335	isochorismatase
MPOP_RS21630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MPOP_RS21655	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MPOP_RS21670	COG3956	TIGRFAM MazG family protein
MPOP_RS21690	COG2301	Belongs to the HpcH HpaI aldolase family
MPOP_RS21700	COG3706	GGDEF domain
MPOP_RS21720	COG2199	diguanylate cyclase activity
MPOP_RS21720	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MPOP_RS21750	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MPOP_RS21755	COG2226	methyltransferase
MPOP_RS21765	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MPOP_RS21770	COG1028	Short-chain dehydrogenase reductase Sdr
MPOP_RS21775	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MPOP_RS21790	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MPOP_RS21805	COG0359	binds to the 23S rRNA
MPOP_RS21815	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MPOP_RS21820	COG0360	Binds together with S18 to 16S ribosomal RNA
MPOP_RS21845	COG1278	Cold shock
MPOP_RS21855	COG0242	peptide deformylase activity
MPOP_RS21895	COG2610	gluconate transmembrane transporter activity
MPOP_RS21900	COG1301	dicarboxylic acid transport
MPOP_RS21910	COG1027	Aspartate ammonia-lyase
MPOP_RS21930	COG0765	amino acid transport
MPOP_RS21935	COG0765	amino acid transport
MPOP_RS21940	COG1126	abc transporter atp-binding protein
MPOP_RS22010	COG2945	thiolester hydrolase activity
MPOP_RS22015	COG1104	cysteine desulfurase activity
MPOP_RS22020	COG0719	Fe-S assembly protein
MPOP_RS22025	COG0396	ATPase activity
MPOP_RS22030	COG0719	Fe-S assembly protein
MPOP_RS22035	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MPOP_RS22045	COG0316	Belongs to the HesB IscA family
MPOP_RS22050	COG4251	negative regulation of phosphorylation
MPOP_RS22050	COG3706	GGDEF domain
MPOP_RS22050	COG2203	Gaf domain
MPOP_RS22050	COG5001	Diguanylate cyclase
MPOP_RS22055	COG0513	Belongs to the DEAD box helicase family
MPOP_RS22065	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MPOP_RS22095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MPOP_RS22105	COG4181	ATPase activity
MPOP_RS22115	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MPOP_RS22125	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MPOP_RS22130	COG0250	Participates in transcription elongation, termination and antitermination
MPOP_RS22135	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MPOP_RS22140	COG0081	regulation of translation
MPOP_RS22145	COG2124	cytochrome p450
MPOP_RS22150	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MPOP_RS22170	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MPOP_RS22175	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MPOP_RS22205	COG5001	Diguanylate cyclase
MPOP_RS22205	COG3300	MHYT domain
MPOP_RS22220	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MPOP_RS22225	COG0222	ribosome binding
MPOP_RS22230	COG0085	RNA polymerase activity
MPOP_RS22235	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MPOP_RS22240	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MPOP_RS22245	COG0251	oxidation-reduction process
MPOP_RS22250	COG2261	transglycosylase associated protein
MPOP_RS22275	COG1185	polyribonucleotide nucleotidyltransferase activity
MPOP_RS22280	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MPOP_RS22290	COG0531	amino acid
MPOP_RS22295	COG0708	Exodeoxyribonuclease III
MPOP_RS22305	COG5001	Diguanylate cyclase
MPOP_RS22315	COG1674	ftsk spoiiie
MPOP_RS22325	COG0784	Response regulator, receiver
MPOP_RS22335	COG2807	transmembrane transport
MPOP_RS22365	COG0730	response to heat
MPOP_RS22370	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MPOP_RS22375	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MPOP_RS22385	COG1959	2 iron, 2 sulfur cluster binding
MPOP_RS22390	COG3634	alkyl hydroperoxide reductase activity
MPOP_RS22400	COG4191	Histidine kinase
MPOP_RS22400	COG0784	Response regulator, receiver
MPOP_RS22420	COG0556	nucleotide-excision repair
MPOP_RS22435	COG0583	DNA-binding transcription factor activity
MPOP_RS22445	COG2514	catechol 2,3-dioxygenase activity
MPOP_RS22460	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MPOP_RS22470	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MPOP_RS22475	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MPOP_RS22500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MPOP_RS22515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MPOP_RS22520	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MPOP_RS22545	COG4251	negative regulation of phosphorylation
MPOP_RS22580	COG2204	response regulator
MPOP_RS22585	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MPOP_RS22595	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MPOP_RS22600	COG1766	The M ring may be actively involved in energy transduction
MPOP_RS22620	COG0482	sulfurtransferase activity
MPOP_RS22630	COG0398	Pfam SNARE associated Golgi protein
MPOP_RS22665	COG1960	acyl-CoA dehydrogenase activity
MPOP_RS22670	COG0009	L-threonylcarbamoyladenylate synthase
MPOP_RS22685	COG4251	negative regulation of phosphorylation
MPOP_RS22690	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
MPOP_RS22700	COG4191	Histidine kinase
MPOP_RS22700	COG0784	Response regulator, receiver
MPOP_RS22745	COG4774	siderophore transport
MPOP_RS22765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MPOP_RS22785	COG0489	protein tyrosine kinase activity
MPOP_RS22785	COG3206	protein involved in exopolysaccharide biosynthesis
MPOP_RS22790	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MPOP_RS22795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MPOP_RS22805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MPOP_RS22815	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
MPOP_RS22815	COG0662	Cupin 2, conserved barrel domain protein
MPOP_RS22825	COG2197	response regulator
MPOP_RS22870	COG0714	Associated with various cellular activities
MPOP_RS22880	COG2010	Cytochrome c
MPOP_RS22885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MPOP_RS22890	COG4993	Dehydrogenase
MPOP_RS22910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MPOP_RS22920	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MPOP_RS22925	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MPOP_RS22955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MPOP_RS22970	COG0848	biopolymer transport protein
MPOP_RS22985	COG4178	(ABC) transporter
MPOP_RS23015	COG1116	anion transmembrane transporter activity
MPOP_RS23015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MPOP_RS23020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MPOP_RS23025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MPOP_RS23030	COG0730	response to heat
MPOP_RS23040	COG0446	pyridine nucleotide-disulphide oxidoreductase
MPOP_RS23075	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MPOP_RS23090	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MPOP_RS23095	COG1278	Cold shock
MPOP_RS23125	COG0745	RESPONSE REGULATOR receiver
MPOP_RS23130	COG0318	PFAM AMP-dependent synthetase and ligase
MPOP_RS23140	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MPOP_RS23145	COG0463	Glycosyl transferase, family 2
MPOP_RS23160	COG2072	flavoprotein involved in K transport
MPOP_RS23175	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MPOP_RS23185	COG3920	Histidine kinase
MPOP_RS23190	COG2801	Transposase and inactivated derivatives
MPOP_RS23205	COG0583	DNA-binding transcription factor activity
MPOP_RS23210	COG0667	Aldo Keto reductase
MPOP_RS23220	COG0084	hydrolase, TatD family'
MPOP_RS23245	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MPOP_RS23250	COG1177	transmembrane transport
MPOP_RS23255	COG1176	ABC-type spermidine putrescine transport system, permease component I
MPOP_RS23290	COG2271	Major facilitator Superfamily
MPOP_RS23295	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MPOP_RS23305	COG3622	Belongs to the hyi family
MPOP_RS23310	COG1028	Short-chain dehydrogenase reductase Sdr
MPOP_RS23315	COG0247	lactate metabolic process
MPOP_RS23395	COG0697	spore germination
MPOP_RS23415	COG1620	l-lactate permease
MPOP_RS23420	COG3546	catalase activity
MPOP_RS23440	COG3737	Protein of unknown function (DUF498/DUF598)
MPOP_RS23450	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MPOP_RS23455	COG1862	Preprotein translocase
MPOP_RS23470	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MPOP_RS23475	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MPOP_RS23480	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MPOP_RS23495	COG1846	Transcriptional regulator
MPOP_RS23505	COG1024	Enoyl-CoA hydratase
MPOP_RS23520	COG0113	porphobilinogen synthase activity
MPOP_RS23535	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
MPOP_RS23550	COG0110	maltose O-acetyltransferase activity
MPOP_RS23555	COG2321	neutral zinc metallopeptidase
MPOP_RS23560	COG1573	uracil-dna glycosylase
MPOP_RS23570	COG3191	aminopeptidase activity
MPOP_RS23585	COG0626	cystathionine gamma-synthase activity
MPOP_RS23590	COG0583	DNA-binding transcription factor activity
MPOP_RS23595	COG2814	Major facilitator Superfamily
MPOP_RS23600	COG0259	pyridoxamine-phosphate oxidase activity
MPOP_RS23610	COG1216	Glycosyl transferase, family 2
MPOP_RS23610	COG0438	transferase activity, transferring glycosyl groups
MPOP_RS23620	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MPOP_RS23625	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MPOP_RS23635	COG0488	(ABC) transporter
MPOP_RS23660	COG4166	transmembrane transport
MPOP_RS23665	COG0601	transmembrane transport
MPOP_RS23670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MPOP_RS23680	COG2271	Major facilitator Superfamily
MPOP_RS23690	COG3609	addiction module antidote protein, CC2985 family
MPOP_RS23710	COG0655	NAD(P)H dehydrogenase (quinone) activity
MPOP_RS23720	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MPOP_RS23730	COG1643	Atp-dependent helicase
MPOP_RS23750	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MPOP_RS23760	COG0406	alpha-ribazole phosphatase activity
MPOP_RS23765	COG2326	polyphosphate kinase activity
MPOP_RS23770	COG2258	MOSC domain
MPOP_RS23775	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MPOP_RS23780	COG0484	heat shock protein binding
MPOP_RS23790	COG0259	pyridoxamine-phosphate oxidase activity
MPOP_RS23800	COG1028	Short-chain dehydrogenase reductase Sdr
MPOP_RS23810	COG1051	belongs to the nudix hydrolase family
MPOP_RS23825	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MPOP_RS23830	COG0354	folic acid binding
MPOP_RS23835	COG2818	Glycosylase
MPOP_RS23840	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
MPOP_RS23850	COG1722	exodeoxyribonuclease VII activity
MPOP_RS23855	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MPOP_RS23860	COG2032	superoxide dismutase activity
MPOP_RS23865	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MPOP_RS23870	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MPOP_RS23895	COG1473	amidohydrolase
MPOP_RS23900	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MPOP_RS23900	COG2169	Transcriptional regulator
MPOP_RS23910	COG0537	adenosine 5'-monophosphoramidase activity
MPOP_RS23925	COG3387	PFAM Glycoside hydrolase 15-related
MPOP_RS23935	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MPOP_RS23940	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MPOP_RS23945	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MPOP_RS23955	COG0252	asparaginase activity
MPOP_RS23965	COG0398	Pfam SNARE associated Golgi protein
MPOP_RS23980	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MPOP_RS23985	COG1845	cytochrome c oxidase, subunit III
MPOP_RS23990	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MPOP_RS23995	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MPOP_RS24000	COG0477	Major facilitator Superfamily
MPOP_RS24005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MPOP_RS24025	COG2197	response regulator
MPOP_RS24035	COG2197	response regulator
MPOP_RS24040	COG2197	response regulator
MPOP_RS24120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MPOP_RS24125	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MPOP_RS24195	COG0438	transferase activity, transferring glycosyl groups
MPOP_RS24210	COG0657	acetylesterase activity
MPOP_RS24220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MPOP_RS24230	COG1960	acyl-CoA dehydrogenase activity
MPOP_RS24240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MPOP_RS24245	COG1116	anion transmembrane transporter activity
MPOP_RS24245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MPOP_RS24250	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MPOP_RS24255	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MPOP_RS24285	COG1877	trehalose-phosphatase activity
MPOP_RS24310	COG3383	formate dehydrogenase (NAD+) activity
MPOP_RS24330	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MPOP_RS24345	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MPOP_RS24350	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MPOP_RS24355	COG1741	Belongs to the pirin family
MPOP_RS24360	COG0433	COG0433 Predicted ATPase
MPOP_RS24410	COG1597	lipid kinase activity
MPOP_RS24420	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MPOP_RS24430	COG2205	protein histidine kinase activity
MPOP_RS24430	COG0784	Response regulator, receiver
MPOP_RS24430	COG5002	protein histidine kinase activity
MPOP_RS24440	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MPOP_RS24445	COG3178	'Phosphotransferase
MPOP_RS24450	COG2205	protein histidine kinase activity
MPOP_RS24455	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MPOP_RS24470	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MPOP_RS24480	COG3657	addiction module killer protein
MPOP_RS24485	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MPOP_RS24490	COG1024	Enoyl-CoA hydratase
MPOP_RS24500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MPOP_RS24510	COG1074	ATP-dependent DNA helicase activity
MPOP_RS24515	COG2133	pyrroloquinoline quinone binding
MPOP_RS24525	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MPOP_RS24530	COG0285	dihydrofolate synthase activity
MPOP_RS24535	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MPOP_RS24540	COG0159	tryptophan synthase activity
MPOP_RS24545	COG2816	NAD+ diphosphatase activity
MPOP_RS24560	COG0513	Belongs to the DEAD box helicase family
MPOP_RS24580	COG0351	phosphomethylpyrimidine kinase
MPOP_RS24580	COG0352	thiamine-phosphate diphosphorylase activity
MPOP_RS24580	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MPOP_RS24585	COG0531	amino acid
MPOP_RS24595	COG3034	peptidoglycan biosynthetic process
MPOP_RS24600	COG4988	ABC transporter
MPOP_RS24615	COG0121	glutamine amidotransferase
MPOP_RS24625	COG4957	zinc ion binding
MPOP_RS24640	COG0633	Ferredoxin
MPOP_RS24655	COG1396	sequence-specific DNA binding
MPOP_RS24660	COG0351	phosphomethylpyrimidine kinase
MPOP_RS24665	COG0352	thiamine-phosphate diphosphorylase activity
MPOP_RS24680	COG4957	zinc ion binding
MPOP_RS24700	COG2264	protein methyltransferase activity
MPOP_RS24705	COG0006	proline dipeptidase activity
MPOP_RS24705	COG0006	proline dipeptidase activity
MPOP_RS24720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MPOP_RS24760	COG0625	glutathione transferase activity
MPOP_RS24770	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MPOP_RS24775	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MPOP_RS24780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MPOP_RS24785	COG1116	anion transmembrane transporter activity
MPOP_RS24790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MPOP_RS24795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MPOP_RS24800	COG1116	anion transmembrane transporter activity
MPOP_RS24800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MPOP_RS24815	COG3387	PFAM Glycoside hydrolase 15-related
MPOP_RS24825	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MPOP_RS24830	COG0586	Pfam SNARE associated Golgi protein
MPOP_RS24860	COG1054	Belongs to the UPF0176 family
MPOP_RS24865	COG0438	transferase activity, transferring glycosyl groups
MPOP_RS24875	COG3916	Acyl-homoserine-lactone synthase
MPOP_RS24880	COG2197	response regulator
MPOP_RS24935	COG3920	Histidine kinase
MPOP_RS24935	COG2202	Pas domain
MPOP_RS24995	COG0673	inositol 2-dehydrogenase activity
MPOP_RS25005	COG0583	DNA-binding transcription factor activity
MPOP_RS25010	COG1063	alcohol dehydrogenase
MPOP_RS25015	COG2202	Pas domain
MPOP_RS25015	COG3920	Histidine kinase
MPOP_RS25025	COG1028	Short-chain dehydrogenase reductase Sdr
MPOP_RS25040	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MPOP_RS25045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MPOP_RS25060	COG0628	permease
MPOP_RS25075	COG3328	transposase activity
MPOP_RS25115	COG0483	inositol monophosphate 1-phosphatase activity
MPOP_RS25120	COG0628	permease
MPOP_RS25125	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MPOP_RS25135	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MPOP_RS25140	COG3871	stress protein (general stress protein 26)
MPOP_RS25150	COG0489	protein tyrosine kinase activity
MPOP_RS25155	COG0746	molybdenum cofactor guanylyltransferase activity
MPOP_RS25160	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MPOP_RS25170	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MPOP_RS25175	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MPOP_RS25195	COG2205	protein histidine kinase activity
MPOP_RS25195	COG0784	Response regulator, receiver
MPOP_RS25245	COG2111	Na H antiporter
MPOP_RS25250	COG1006	Multisubunit Na H antiporter MnhC subunit
MPOP_RS25255	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MPOP_RS25300	COG0831	urea catabolic process
MPOP_RS25310	COG0804	urea catabolic process
MPOP_RS25330	COG0830	nickel cation binding
MPOP_RS25335	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MPOP_RS25340	COG0829	nickel cation binding
MPOP_RS25350	COG0004	ammonium transporteR
MPOP_RS25370	COG0038	chloride channel
MPOP_RS25390	COG1294	oxidase, subunit
MPOP_RS25395	COG1271	oxidase subunit
MPOP_RS25425	COG3609	addiction module antidote protein, CC2985 family
MPOP_RS25465	COG1320	monovalent cation:proton antiporter activity
MPOP_RS25470	COG2212	antiporter activity
MPOP_RS25475	COG1863	multisubunit Na H antiporter MnhE subunit
MPOP_RS25480	COG0651	ATP synthesis coupled electron transport
MPOP_RS25485	COG1006	Multisubunit Na H antiporter MnhC subunit
MPOP_RS25490	COG2111	Na H antiporter
MPOP_RS25490	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MPOP_RS25510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MPOP_RS25540	COG0667	Aldo Keto reductase
MPOP_RS25545	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MPOP_RS25580	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MPOP_RS25585	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MPOP_RS25590	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MPOP_RS25605	COG0275	rRNA processing
MPOP_RS25615	COG3609	addiction module antidote protein, CC2985 family
MPOP_RS25620	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MPOP_RS25635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MPOP_RS25655	COG1024	Enoyl-CoA hydratase
MPOP_RS25675	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MPOP_RS25700	COG0754	glutathionylspermidine amidase activity
MPOP_RS25710	COG3766	membrane
MPOP_RS25715	COG0504	CTP synthase activity
MPOP_RS25735	COG0149	triose-phosphate isomerase activity
MPOP_RS25740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MPOP_RS25745	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MPOP_RS25760	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MPOP_RS25765	COG0134	indole-3-glycerol-phosphate synthase activity
MPOP_RS25770	COG0315	cyclic pyranopterin monophosphate synthase activity
MPOP_RS25775	COG0303	'Molybdopterin
MPOP_RS25780	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
MPOP_RS25790	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MPOP_RS25795	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MPOP_RS25805	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MPOP_RS25810	COG1671	Belongs to the UPF0178 family
MPOP_RS25815	COG0372	Belongs to the citrate synthase family
MPOP_RS25820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MPOP_RS25830	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MPOP_RS25840	COG0477	Major facilitator Superfamily
MPOP_RS25850	COG0473	3-isopropylmalate dehydrogenase activity
MPOP_RS25860	COG0667	Aldo Keto reductase
MPOP_RS25870	COG2972	Histidine kinase
MPOP_RS25870	COG0840	transmembrane signaling receptor activity
MPOP_RS25885	COG0525	valine-tRNA ligase activity
MPOP_RS25900	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MPOP_RS25935	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MPOP_RS25965	COG0573	inorganic phosphate transmembrane transporter activity
MPOP_RS25970	COG0581	inorganic phosphate transmembrane transporter activity
MPOP_RS25975	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MPOP_RS25980	COG0704	Plays a role in the regulation of phosphate uptake
MPOP_RS25985	COG0745	RESPONSE REGULATOR receiver
MPOP_RS26000	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MPOP_RS26010	COG1492	cobalamin metabolic process
MPOP_RS26025	COG2814	Major facilitator Superfamily
MPOP_RS26040	COG3237	CsbD-like
MPOP_RS26045	COG1028	Short-chain dehydrogenase reductase Sdr
MPOP_RS26050	COG0825	malonyl-CoA metabolic process
MPOP_RS26060	COG3034	peptidoglycan biosynthetic process
MPOP_RS26065	COG0335	large ribosomal subunit rRNA binding
MPOP_RS26080	COG2951	lytic endotransglycosylase activity
MPOP_RS26085	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MPOP_RS26095	COG1183	phosphatidylcholine synthase activity
MPOP_RS26100	COG0688	phosphatidylethanolamine metabolic process
MPOP_RS26105	COG5265	(ABC) transporter
MPOP_RS26125	COG0215	cysteine-tRNA ligase activity
MPOP_RS26135	COG2161	toxin-antitoxin pair type II binding
MPOP_RS26140	COG3045	CreA protein
MPOP_RS26155	COG2814	Major facilitator Superfamily
MPOP_RS26165	COG2226	methyltransferase
MPOP_RS26170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MPOP_RS26175	COG1566	PFAM secretion protein HlyD family protein
MPOP_RS26200	COG0625	glutathione transferase activity
MPOP_RS26205	COG0823	Involved in the tonB-independent uptake of proteins
MPOP_RS26215	COG0848	biopolymer transport protein
MPOP_RS26220	COG0811	peptide transport
MPOP_RS26225	COG0840	transmembrane signaling receptor activity
MPOP_RS26230	COG0824	Thioesterase
MPOP_RS26240	COG1408	metallophosphoesterase
MPOP_RS26245	COG2255	four-way junction helicase activity
MPOP_RS26255	COG0783	Belongs to the Dps family
MPOP_RS26260	COG1042	CoA-binding domain protein
MPOP_RS26260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MPOP_RS26260	COG0045	succinate-CoA ligase (ADP-forming) activity
MPOP_RS26265	COG0235	Class ii aldolase
MPOP_RS26270	COG4957	zinc ion binding
MPOP_RS26290	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
MPOP_RS26300	COG1192	Involved in chromosome partitioning
MPOP_RS26320	COG0459	protein refolding
MPOP_RS26325	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MPOP_RS26330	COG0598	Magnesium transport protein CorA
MPOP_RS26335	COG2095	MarC family integral membrane protein
MPOP_RS26345	COG0277	FAD linked oxidase domain protein
MPOP_RS26350	COG0306	phosphate transporter
MPOP_RS26375	COG0662	Cupin 2, conserved barrel domain protein
MPOP_RS26375	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
MPOP_RS26390	COG3739	integral membrane protein
MPOP_RS26400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MPOP_RS26405	COG0484	heat shock protein binding
MPOP_RS26410	COG1686	Belongs to the peptidase S11 family
MPOP_RS26415	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MPOP_RS26435	COG0156	8-amino-7-oxononanoate synthase activity
MPOP_RS26445	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MPOP_RS26480	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
MPOP_RS26485	COG1429	ligase activity, forming nitrogen-metal bonds
MPOP_RS26490	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
MPOP_RS26495	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
MPOP_RS26515	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MPOP_RS26520	COG2211	Major facilitator Superfamily
MPOP_RS26525	COG0644	oxidoreductase
MPOP_RS26545	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
MPOP_RS26550	COG0363	glucosamine-6-phosphate deaminase activity
MPOP_RS26560	COG1132	(ABC) transporter
MPOP_RS26565	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MPOP_RS26580	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MPOP_RS26580	COG3264	Mechanosensitive ion channel
MPOP_RS26610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MPOP_RS26620	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MPOP_RS26625	COG0037	tRNA processing
MPOP_RS26635	COG2885	chlorophyll binding
MPOP_RS26645	COG0745	RESPONSE REGULATOR receiver
MPOP_RS26660	COG0181	hydroxymethylbilane synthase activity
MPOP_RS26700	COG3685	Protein conserved in bacteria
MPOP_RS26705	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MPOP_RS26715	COG0028	Belongs to the TPP enzyme family
MPOP_RS26745	COG0367	asparagine synthase
MPOP_RS26765	COG0745	RESPONSE REGULATOR receiver
MPOP_RS26770	COG3437	response regulator, receiver
MPOP_RS26830	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MPOP_RS26850	COG0776	regulation of translation
MPOP_RS26870	COG3609	addiction module antidote protein, CC2985 family
MPOP_RS26890	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MPOP_RS26905	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MPOP_RS26935	COG3328	transposase activity
MPOP_RS26995	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MPOP_RS27100	COG3920	Histidine kinase
MPOP_RS27100	COG2202	Pas domain
MPOP_RS27115	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MPOP_RS27140	COG0463	Glycosyl transferase, family 2
MPOP_RS27140	COG0457	Tetratricopeptide repeat
MPOP_RS27165	COG2202	Pas domain
MPOP_RS27165	COG3920	Histidine kinase
MPOP_RS27175	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MPOP_RS27355	COG3474	cytochrome
MPOP_RS27385	COG3237	CsbD-like
MPOP_RS27445	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MPOP_RS27570	COG5487	UPF0391 membrane protein
MPOP_RS27620	COG0401	homolog of Blt101
MPOP_RS27730	COG1309	transcriptional regulator
MPOP_RS27800	COG4106	trans-aconitate 2-methyltransferase activity
MPOP_RS27935	COG5487	UPF0391 membrane protein
MPOP_RS27945	COG1335	isochorismatase
MPOP_RS27955	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MPOP_RS28050	COG4566	intracellular signal transduction