locus-tag	class	description
CEK71_RS00010	COG3335	DDE superfamily endonuclease
CEK71_RS00025	COG2177	Part of the ABC transporter FtsEX involved in
CEK71_RS00030	COG2884	Cell division ATP-binding protein ftsE
CEK71_RS00035	COG0552	protein localization to endoplasmic reticulum
CEK71_RS00065	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CEK71_RS00080	COG4969	Belongs to the N-Me-Phe pilin family
CEK71_RS00095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEK71_RS00115	COG1229	Formylmethanofuran dehydrogenase subunit A
CEK71_RS00135	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
CEK71_RS00150	COG0745	RESPONSE REGULATOR receiver
CEK71_RS00155	COG2205	protein histidine kinase activity
CEK71_RS00160	COG1278	Cold shock
CEK71_RS00170	COG0363	glucosamine-6-phosphate deaminase activity
CEK71_RS00175	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CEK71_RS00185	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CEK71_RS00190	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CEK71_RS00195	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CEK71_RS00195	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CEK71_RS00215	COG0742	ribosomal rna small subunit methyltransferase
CEK71_RS00220	COG0822	iron-sulfur transferase activity
CEK71_RS00230	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CEK71_RS00240	COG0719	Fe-S assembly protein
CEK71_RS00245	COG0396	ATPase activity
CEK71_RS00260	COG0719	Fe-S assembly protein
CEK71_RS00265	COG0719	Fe-S assembly protein
CEK71_RS00275	COG1381	Involved in DNA repair and RecF pathway recombination
CEK71_RS00280	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CEK71_RS00285	COG0571	ribonuclease III activity
CEK71_RS00295	COG0681	Belongs to the peptidase S26 family
CEK71_RS00300	COG0481	GTPase activity
CEK71_RS00305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEK71_RS00310	COG1765	OsmC-like protein
CEK71_RS00315	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CEK71_RS00320	COG1648	precorrin-2 dehydrogenase activity
CEK71_RS00320	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CEK71_RS00325	COG0425	Belongs to the sulfur carrier protein TusA family
CEK71_RS00335	COG0494	nUDIX hydrolase
CEK71_RS00350	COG0513	Belongs to the DEAD box helicase family
CEK71_RS00365	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CEK71_RS00385	COG0625	glutathione transferase activity
CEK71_RS00395	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CEK71_RS00410	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CEK71_RS00425	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CEK71_RS00440	COG0647	UMP catabolic process
CEK71_RS00445	COG2376	Dihydroxyacetone kinase
CEK71_RS00450	COG1461	Dihydroxyacetone kinase
CEK71_RS00465	COG1561	YicC-like family, N-terminal region
CEK71_RS00470	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CEK71_RS00475	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CEK71_RS00490	COG0697	spore germination
CEK71_RS00515	COG4636	protein conserved in cyanobacteria
CEK71_RS00535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEK71_RS00540	COG3028	Belongs to the UPF0307 family
CEK71_RS00550	COG2974	May be involved in recombination
CEK71_RS00565	COG0033	Phosphoglucomutase
CEK71_RS00605	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEK71_RS00610	COG0573	inorganic phosphate transmembrane transporter activity
CEK71_RS00640	COG0513	Belongs to the DEAD box helicase family
CEK71_RS00645	COG1011	Hydrolase
CEK71_RS00650	COG0494	nUDIX hydrolase
CEK71_RS00710	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEK71_RS00715	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CEK71_RS00725	COG3706	GGDEF domain
CEK71_RS00770	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CEK71_RS00775	COG0179	Fumarylacetoacetate (FAA) hydrolase
CEK71_RS00810	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CEK71_RS00820	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEK71_RS00825	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CEK71_RS00855	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEK71_RS00855	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEK71_RS00860	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CEK71_RS00880	COG1136	(ABC) transporter
CEK71_RS00890	COG0735	belongs to the Fur family
CEK71_RS00895	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEK71_RS00905	COG0483	inositol monophosphate 1-phosphatase activity
CEK71_RS00930	COG0457	Tetratricopeptide repeat
CEK71_RS00935	COG1490	D-aminoacyl-tRNA deacylase activity
CEK71_RS00950	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CEK71_RS00965	COG2132	Multicopper oxidase
CEK71_RS00980	COG0628	permease
CEK71_RS00990	COG3338	carbonate dehydratase activity
CEK71_RS01000	COG3335	DDE superfamily endonuclease
CEK71_RS01020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEK71_RS01025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEK71_RS01035	COG2226	methyltransferase
CEK71_RS01040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CEK71_RS01045	COG1522	sequence-specific DNA binding
CEK71_RS01070	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEK71_RS01100	COG1192	Involved in chromosome partitioning
CEK71_RS01105	COG1475	DNA binding
CEK71_RS01110	COG3251	PFAM MbtH domain protein
CEK71_RS01155	COG4615	Cyclic peptide transporter
CEK71_RS01170	COG1538	Outer membrane efflux protein
CEK71_RS01175	COG1566	PFAM secretion protein HlyD family protein
CEK71_RS01190	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CEK71_RS01190	COG0574	Belongs to the PEP-utilizing enzyme family
CEK71_RS01200	COG1294	oxidase, subunit
CEK71_RS01230	COG0745	RESPONSE REGULATOR receiver
CEK71_RS01235	COG3842	ATPase activity
CEK71_RS01240	COG4120	Belongs to the binding-protein-dependent transport system permease family
CEK71_RS01245	COG1366	Belongs to the anti-sigma-factor antagonist family
CEK71_RS01260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CEK71_RS01265	COG0583	DNA-binding transcription factor activity
CEK71_RS01280	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CEK71_RS01285	COG4650	regulator
CEK71_RS01290	COG1690	Belongs to the RtcB family
CEK71_RS01295	COG0430	RNA-3'-phosphate cyclase activity
CEK71_RS01365	COG1595	DNA-templated transcription, initiation
CEK71_RS01380	COG0656	L-ascorbic acid biosynthetic process
CEK71_RS01410	COG3259	Nickel-dependent hydrogenase
CEK71_RS01420	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
CEK71_RS01425	COG3383	formate dehydrogenase (NAD+) activity
CEK71_RS01430	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CEK71_RS01465	COG0045	succinate-CoA ligase (ADP-forming) activity
CEK71_RS01465	COG1042	CoA-binding domain protein
CEK71_RS01465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEK71_RS01495	COG3119	arylsulfatase activity
CEK71_RS01500	COG0745	RESPONSE REGULATOR receiver
CEK71_RS01510	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CEK71_RS01515	COG0583	DNA-binding transcription factor activity
CEK71_RS01535	COG5001	Diguanylate cyclase
CEK71_RS01535	COG3447	MASE1 domain protein
CEK71_RS01535	COG5002	protein histidine kinase activity
CEK71_RS01540	COG3437	response regulator, receiver
CEK71_RS01590	COG1358	cellular component organization or biogenesis
CEK71_RS01610	COG3794	PFAM blue (type 1) copper domain protein
CEK71_RS01680	COG2969	positive regulation of protein catabolic process
CEK71_RS01685	COG0625	glutathione transferase activity
CEK71_RS01690	COG2857	Cytochrome c1
CEK71_RS01695	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CEK71_RS01700	COG0723	plastoquinol--plastocyanin reductase activity
CEK71_RS01710	COG2223	nitrite transmembrane transporter activity
CEK71_RS01715	COG0515	serine threonine protein kinase
CEK71_RS01740	COG1215	transferase activity, transferring glycosyl groups
CEK71_RS01765	COG0326	Molecular chaperone. Has ATPase activity
CEK71_RS01780	COG0826	peptidase U32
CEK71_RS01785	COG2960	long-chain fatty acid transporting porin activity
CEK71_RS01795	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CEK71_RS01820	COG3437	response regulator, receiver
CEK71_RS01840	COG5001	Diguanylate cyclase
CEK71_RS01860	COG0798	PFAM Bile acid sodium symporter
CEK71_RS01870	COG0640	Transcriptional regulator
CEK71_RS01895	COG4636	protein conserved in cyanobacteria
CEK71_RS01900	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CEK71_RS01915	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CEK71_RS01920	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CEK71_RS01925	COG0459	protein refolding
CEK71_RS01935	COG0606	chelatase, subunit chli
CEK71_RS01940	COG0463	Glycosyl transferase, family 2
CEK71_RS01975	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CEK71_RS02000	COG0673	inositol 2-dehydrogenase activity
CEK71_RS02010	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEK71_RS02025	COG0825	malonyl-CoA metabolic process
CEK71_RS02060	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEK71_RS02070	COG0756	dUTP diphosphatase activity
CEK71_RS02075	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CEK71_RS02080	COG2198	Histidine kinase
CEK71_RS02080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEK71_RS02080	COG0784	Response regulator, receiver
CEK71_RS02080	COG2205	protein histidine kinase activity
CEK71_RS02085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEK71_RS02135	COG1183	phosphatidylcholine synthase activity
CEK71_RS02140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CEK71_RS02145	COG1573	uracil-dna glycosylase
CEK71_RS02150	COG0456	acetyltransferase
CEK71_RS02155	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CEK71_RS02165	COG2124	cytochrome p450
CEK71_RS02170	COG2129	metallophosphoesterase
CEK71_RS02175	COG0702	epimerase
CEK71_RS02180	COG0702	epimerase
CEK71_RS02205	COG0670	Belongs to the BI1 family
CEK71_RS02215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEK71_RS02220	COG0596	Alpha beta hydrolase
CEK71_RS02275	COG2198	Histidine kinase
CEK71_RS02275	COG5002	protein histidine kinase activity
CEK71_RS02275	COG0784	Response regulator, receiver
CEK71_RS02320	COG1131	(ABC) transporter
CEK71_RS02325	COG0842	Transport permease protein
CEK71_RS02375	COG0419	ATPase involved in DNA repair
CEK71_RS02380	COG0625	glutathione transferase activity
CEK71_RS02400	COG1686	Belongs to the peptidase S11 family
CEK71_RS02410	COG2131	deaminase
CEK71_RS02415	COG3384	dioxygenase
CEK71_RS02450	COG4636	protein conserved in cyanobacteria
CEK71_RS02480	COG0367	asparagine synthase
CEK71_RS02485	COG0438	transferase activity, transferring glycosyl groups
CEK71_RS02515	COG0489	protein tyrosine kinase activity
CEK71_RS02550	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CEK71_RS02555	COG0473	3-isopropylmalate dehydrogenase activity
CEK71_RS02560	COG0066	3-isopropylmalate dehydratase activity
CEK71_RS02570	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CEK71_RS02575	COG0563	adenylate kinase activity
CEK71_RS02580	COG0352	thiamine-phosphate diphosphorylase activity
CEK71_RS02585	COG0351	phosphomethylpyrimidine kinase
CEK71_RS02600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEK71_RS02605	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CEK71_RS02610	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CEK71_RS02640	COG0326	Molecular chaperone. Has ATPase activity
CEK71_RS02655	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
CEK71_RS02665	COG0189	ligase activity
CEK71_RS02670	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEK71_RS02680	COG1666	GTP binding
CEK71_RS02690	COG0617	tRNA 3'-terminal CCA addition
CEK71_RS02705	COG3002	Belongs to the UPF0753 family
CEK71_RS02710	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CEK71_RS02720	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CEK71_RS02735	COG0148	phosphopyruvate hydratase activity
CEK71_RS02755	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CEK71_RS02765	COG0504	CTP synthase activity
CEK71_RS02770	COG0037	tRNA processing
CEK71_RS02775	COG1968	undecaprenyl-diphosphatase activity
CEK71_RS02800	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CEK71_RS02805	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEK71_RS02815	COG1028	Short-chain dehydrogenase reductase Sdr
CEK71_RS02820	COG1051	belongs to the nudix hydrolase family
CEK71_RS02830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEK71_RS02840	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEK71_RS02870	COG0438	transferase activity, transferring glycosyl groups
CEK71_RS02875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEK71_RS02920	COG2801	Transposase and inactivated derivatives
CEK71_RS02930	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CEK71_RS02950	COG1741	Belongs to the pirin family
CEK71_RS02955	COG0583	DNA-binding transcription factor activity
CEK71_RS02975	COG0297	glycogen (starch) synthase activity
CEK71_RS02980	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CEK71_RS02985	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CEK71_RS03000	COG2226	methyltransferase
CEK71_RS03025	COG1278	Cold shock
CEK71_RS03035	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CEK71_RS03040	COG1702	phosphate starvation-inducible protein PhoH
CEK71_RS03045	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CEK71_RS03050	COG4535	Mg2 and Co2 transporter CorC
CEK71_RS03055	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CEK71_RS03065	COG0569	domain protein
CEK71_RS03075	COG0489	protein tyrosine kinase activity
CEK71_RS03085	COG0717	Belongs to the dCTP deaminase family
CEK71_RS03090	COG0402	S-adenosylhomocysteine deaminase activity
CEK71_RS03095	COG4172	Belongs to the ABC transporter superfamily
CEK71_RS03145	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CEK71_RS03145	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CEK71_RS03150	COG0802	atpase or kinase
CEK71_RS03160	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CEK71_RS03165	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CEK71_RS03180	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CEK71_RS03205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEK71_RS03205	COG2169	Transcriptional regulator
CEK71_RS03215	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEK71_RS03240	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CEK71_RS03250	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CEK71_RS03250	COG0047	phosphoribosylformylglycinamidine synthase activity
CEK71_RS03260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CEK71_RS03265	COG0019	diaminopimelate decarboxylase activity
CEK71_RS03270	COG0189	ligase activity
CEK71_RS03285	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CEK71_RS03300	COG0328	RNA-DNA hybrid ribonuclease activity
CEK71_RS03310	COG1388	LysM domain
CEK71_RS03310	COG0741	lytic transglycosylase activity
CEK71_RS03320	COG2076	Multidrug Resistance protein
CEK71_RS03330	COG2920	part of a sulfur-relay system
CEK71_RS03340	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CEK71_RS03345	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CEK71_RS03350	COG0613	PHP domain protein
CEK71_RS03355	COG1132	(ABC) transporter
CEK71_RS03365	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEK71_RS03410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEK71_RS03415	COG1459	type II secretion system
CEK71_RS03430	COG2165	general secretion pathway protein
CEK71_RS03440	COG3156	type II secretion system protein K
CEK71_RS03445	COG3166	PFAM Fimbrial assembly family protein
CEK71_RS03460	COG1450	Type ii and iii secretion system protein
CEK71_RS03465	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CEK71_RS03470	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CEK71_RS03485	COG1966	Carbon starvation protein
CEK71_RS03530	COG2909	trisaccharide binding
CEK71_RS03550	COG3646	Phage regulatory protein
CEK71_RS03600	COG3646	Phage regulatory protein
CEK71_RS03615	COG2801	Transposase and inactivated derivatives
CEK71_RS03620	COG4372	Transposase
CEK71_RS03690	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CEK71_RS03695	COG0602	queuosine metabolic process
CEK71_RS03705	COG2885	chlorophyll binding
CEK71_RS03710	COG0823	Involved in the tonB-independent uptake of proteins
CEK71_RS03730	COG0824	Thioesterase
CEK71_RS03735	COG2255	four-way junction helicase activity
CEK71_RS03740	COG0632	four-way junction helicase activity
CEK71_RS03745	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CEK71_RS03750	COG0217	transcriptional regulatory protein
CEK71_RS03765	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEK71_RS03790	COG0123	including yeast histone deacetylase and acetoin utilization protein
CEK71_RS03800	COG1451	nucleotide metabolic process
CEK71_RS03825	COG0714	Associated with various cellular activities
CEK71_RS03845	COG1546	Belongs to the CinA family
CEK71_RS03855	COG3958	Transketolase
CEK71_RS03880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEK71_RS03885	COG1388	LysM domain
CEK71_RS03885	COG4942	peptidase
CEK71_RS03895	COG1763	Mo-molybdopterin cofactor biosynthetic process
CEK71_RS03905	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEK71_RS03915	COG0175	sulfate reduction
CEK71_RS03940	COG0356	it plays a direct role in the translocation of protons across the membrane
CEK71_RS03950	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CEK71_RS03955	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEK71_RS03960	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CEK71_RS03965	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CEK71_RS03970	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CEK71_RS03975	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CEK71_RS03980	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CEK71_RS03985	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CEK71_RS03995	COG0300	oxidoreductase activity
CEK71_RS04020	COG0714	Associated with various cellular activities
CEK71_RS04040	COG2346	COG2346, Truncated hemoglobins
CEK71_RS04055	COG0038	chloride channel
CEK71_RS04060	COG0475	glutathione-regulated potassium exporter activity
CEK71_RS04060	COG0569	domain protein
CEK71_RS04070	COG0730	response to heat
CEK71_RS04080	COG1199	ATP-dependent helicase activity
CEK71_RS04115	COG0784	Response regulator, receiver
CEK71_RS04115	COG2198	Histidine kinase
CEK71_RS04115	COG0643	Histidine kinase
CEK71_RS04120	COG0840	transmembrane signaling receptor activity
CEK71_RS04140	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CEK71_RS04185	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEK71_RS04235	COG3209	COG3209 Rhs family protein
CEK71_RS04240	COG3209	COG3209 Rhs family protein
CEK71_RS04290	COG4191	Histidine kinase
CEK71_RS04295	COG2204	response regulator
CEK71_RS04310	COG4232	protein-disulfide reductase activity
CEK71_RS04315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEK71_RS04325	COG3321	synthase
CEK71_RS04325	COG0604	alcohol dehydrogenase
CEK71_RS04325	COG1028	Short-chain dehydrogenase reductase Sdr
CEK71_RS04330	COG0156	8-amino-7-oxononanoate synthase activity
CEK71_RS04340	COG1028	Short-chain dehydrogenase reductase Sdr
CEK71_RS04345	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CEK71_RS04390	COG2862	Uncharacterized protein family, UPF0114
CEK71_RS04415	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CEK71_RS04420	COG0688	phosphatidylethanolamine metabolic process
CEK71_RS04430	COG0429	hydrolase of the alpha beta-hydrolase fold
CEK71_RS04455	COG3093	addiction module antidote protein HigA
CEK71_RS04470	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CEK71_RS04475	COG0706	membrane insertase activity
CEK71_RS04480	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CEK71_RS04485	COG0594	ribonuclease P activity
CEK71_RS04490	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CEK71_RS04495	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CEK71_RS04500	COG0592	DNA-directed DNA polymerase activity
CEK71_RS04510	COG0187	DNA topoisomerase II activity
CEK71_RS04525	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CEK71_RS04530	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CEK71_RS04535	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CEK71_RS04545	COG2205	protein histidine kinase activity
CEK71_RS04550	COG0745	RESPONSE REGULATOR receiver
CEK71_RS04555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEK71_RS04560	COG4133	protoheme IX ABC transporter activity
CEK71_RS04585	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CEK71_RS04615	COG1138	Cytochrome C-type biogenesis protein
CEK71_RS04620	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CEK71_RS04645	COG1657	PFAM Prenyltransferase squalene oxidase
CEK71_RS04650	COG1562	ergosterol biosynthetic process
CEK71_RS04655	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CEK71_RS04660	COG2854	intermembrane phospholipid transfer
CEK71_RS04665	COG2853	Lipoprotein
CEK71_RS04670	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEK71_RS04690	COG2132	Multicopper oxidase
CEK71_RS04695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEK71_RS04700	COG0006	proline dipeptidase activity
CEK71_RS04745	COG1252	NADH dehydrogenase
CEK71_RS04765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEK71_RS04775	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CEK71_RS04780	COG0166	Belongs to the GPI family
CEK71_RS04795	COG1238	metal cluster binding
CEK71_RS04870	COG2835	tetraacyldisaccharide 4'-kinase activity
CEK71_RS04875	COG1663	tetraacyldisaccharide 4'-kinase activity
CEK71_RS04885	COG0811	peptide transport
CEK71_RS04890	COG2814	Major facilitator Superfamily
CEK71_RS04895	COG1368	sulfuric ester hydrolase activity
CEK71_RS04920	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CEK71_RS04925	COG1160	GTP binding
CEK71_RS04945	COG1194	a g-specific adenine glycosylase
CEK71_RS04955	COG3415	Transposase
CEK71_RS04955	COG2801	Transposase and inactivated derivatives
CEK71_RS04995	COG0582	viral genome integration into host DNA
CEK71_RS05005	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CEK71_RS05075	COG2171	N-acyltransferase activity
CEK71_RS05080	COG0436	Aminotransferase
CEK71_RS05085	COG0501	Belongs to the peptidase M48B family
CEK71_RS05095	COG0203	ribosomal protein L17
CEK71_RS05100	COG0202	RNA polymerase activity
CEK71_RS05105	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CEK71_RS05110	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CEK71_RS05115	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CEK71_RS05120	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CEK71_RS05125	COG0201	protein transport
CEK71_RS05130	COG0200	Binds to the 23S rRNA
CEK71_RS05135	COG1841	ribosomal large subunit assembly
CEK71_RS05140	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CEK71_RS05145	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CEK71_RS05150	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CEK71_RS05155	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CEK71_RS05160	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CEK71_RS05170	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CEK71_RS05175	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CEK71_RS05180	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CEK71_RS05185	COG0255	Belongs to the universal ribosomal protein uL29 family
CEK71_RS05190	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CEK71_RS05195	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CEK71_RS05200	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CEK71_RS05205	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CEK71_RS05210	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CEK71_RS05215	COG0089	rRNA binding
CEK71_RS05220	COG0088	Forms part of the polypeptide exit tunnel
CEK71_RS05225	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CEK71_RS05230	COG0051	transcription antitermination factor activity, RNA binding
CEK71_RS05235	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEK71_RS05240	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEK71_RS05245	COG0049	tRNA binding
CEK71_RS05250	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CEK71_RS05255	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CEK71_RS05260	COG0085	RNA polymerase activity
CEK71_RS05265	COG0222	ribosome binding
CEK71_RS05270	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CEK71_RS05275	COG0081	regulation of translation
CEK71_RS05280	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CEK71_RS05290	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEK71_RS05300	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEK71_RS05330	COG0795	lipopolysaccharide-transporting ATPase activity
CEK71_RS05335	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CEK71_RS05345	COG0525	valine-tRNA ligase activity
CEK71_RS05360	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CEK71_RS05370	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CEK71_RS05380	COG0494	nUDIX hydrolase
CEK71_RS05385	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CEK71_RS05395	COG0425	Belongs to the sulfur carrier protein TusA family
CEK71_RS05395	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEK71_RS05400	COG0268	Binds directly to 16S ribosomal RNA
CEK71_RS05410	COG0196	riboflavin kinase activity
CEK71_RS05425	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CEK71_RS05455	COG0751	glycine-tRNA ligase activity
CEK71_RS05475	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CEK71_RS05485	COG0418	dihydroorotase activity
CEK71_RS05490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CEK71_RS05495	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CEK71_RS05500	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CEK71_RS05510	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CEK71_RS05515	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CEK71_RS05530	COG1054	Belongs to the UPF0176 family
CEK71_RS05535	COG0519	Catalyzes the synthesis of GMP from XMP
CEK71_RS05540	COG0346	lactoylglutathione lyase activity
CEK71_RS05565	COG0436	Aminotransferase
CEK71_RS05570	COG1215	transferase activity, transferring glycosyl groups
CEK71_RS05585	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CEK71_RS05630	COG0248	Ppx GppA phosphatase
CEK71_RS05650	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CEK71_RS05690	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEK71_RS05695	COG0482	sulfurtransferase activity
CEK71_RS05705	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CEK71_RS05710	COG0542	response to heat
CEK71_RS05715	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CEK71_RS05720	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CEK71_RS05725	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CEK71_RS05730	COG0492	ferredoxin-NADP+ reductase activity
CEK71_RS05735	COG1674	ftsk spoiiie
CEK71_RS05740	COG2003	Belongs to the UPF0758 family
CEK71_RS05745	COG0321	lipoyl(octanoyl) transferase activity
CEK71_RS05750	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CEK71_RS05755	COG4804	nuclease activity
CEK71_RS05760	COG1858	cytochrome C peroxidase
CEK71_RS05785	COG3707	response regulator
CEK71_RS05835	COG1216	Glycosyl transferase, family 2
CEK71_RS05840	COG1132	(ABC) transporter
CEK71_RS05850	COG0463	Glycosyl transferase, family 2
CEK71_RS05855	COG1216	Glycosyl transferase, family 2
CEK71_RS05865	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CEK71_RS05875	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CEK71_RS05880	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CEK71_RS05895	COG0358	DNA primase activity
CEK71_RS05900	COG1610	YqeY-like protein
CEK71_RS05905	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CEK71_RS05915	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEK71_RS05920	COG2022	thiamine diphosphate biosynthetic process
CEK71_RS05920	COG2104	thiamine diphosphate biosynthetic process
CEK71_RS05925	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CEK71_RS05940	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CEK71_RS05945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEK71_RS05950	COG1615	UPF0182 protein
CEK71_RS05985	COG0252	asparaginase activity
CEK71_RS06005	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CEK71_RS06010	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CEK71_RS06015	COG0830	nickel cation binding
CEK71_RS06020	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CEK71_RS06040	COG0804	urea catabolic process
CEK71_RS06045	COG0832	Belongs to the urease beta subunit family
CEK71_RS06050	COG0831	urea catabolic process
CEK71_RS06055	COG0829	nickel cation binding
CEK71_RS06080	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEK71_RS06105	COG1335	isochorismatase
CEK71_RS06125	COG1335	isochorismatase
CEK71_RS06155	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEK71_RS06165	COG1596	polysaccharide export
CEK71_RS06170	COG0489	protein tyrosine kinase activity
CEK71_RS06170	COG3206	protein involved in exopolysaccharide biosynthesis
CEK71_RS06175	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CEK71_RS06185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEK71_RS06200	COG0110	maltose O-acetyltransferase activity
CEK71_RS06230	COG0438	transferase activity, transferring glycosyl groups
CEK71_RS06240	COG0110	maltose O-acetyltransferase activity
CEK71_RS06245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEK71_RS06310	COG0489	protein tyrosine kinase activity
CEK71_RS06310	COG3206	protein involved in exopolysaccharide biosynthesis
CEK71_RS06330	COG0463	Glycosyl transferase, family 2
CEK71_RS06350	COG1388	LysM domain
CEK71_RS06350	COG1376	ErfK ybiS ycfS ynhG family protein
CEK71_RS06365	COG1566	PFAM secretion protein HlyD family protein
CEK71_RS06390	COG3920	Histidine kinase
CEK71_RS06400	COG0167	dihydroorotate dehydrogenase activity
CEK71_RS06405	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CEK71_RS06405	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CEK71_RS06405	COG1013	pyruvate-flavodoxin oxidoreductase activity
CEK71_RS06405	COG0674	pyruvate-flavodoxin oxidoreductase activity
CEK71_RS06460	COG3411	Ferredoxin
CEK71_RS06500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEK71_RS06510	COG1538	Outer membrane efflux protein
CEK71_RS06545	COG0729	surface antigen
CEK71_RS06580	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CEK71_RS06595	COG0793	Belongs to the peptidase S41A family
CEK71_RS06605	COG0640	Transcriptional regulator
CEK71_RS06610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEK71_RS06615	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CEK71_RS06620	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CEK71_RS06660	COG0745	RESPONSE REGULATOR receiver
CEK71_RS06665	COG0442	prolyl-tRNA aminoacylation
CEK71_RS06670	COG2989	Protein conserved in bacteria
CEK71_RS06735	COG0335	large ribosomal subunit rRNA binding
CEK71_RS06740	COG0336	Belongs to the RNA methyltransferase TrmD family
CEK71_RS06745	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CEK71_RS06750	COG0228	four-way junction DNA binding
CEK71_RS06755	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CEK71_RS06760	COG4137	Cytochrome C assembly protein
CEK71_RS06770	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CEK71_RS06780	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CEK71_RS06785	COG0305	Participates in initiation and elongation during chromosome replication
CEK71_RS06800	COG0544	peptidyl-prolyl cis-trans isomerase activity
CEK71_RS06805	COG0740	serine-type endopeptidase activity
CEK71_RS06810	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CEK71_RS06820	COG2346	COG2346, Truncated hemoglobins
CEK71_RS06860	COG0805	protein transport
CEK71_RS06865	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CEK71_RS06870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CEK71_RS06875	COG0140	phosphoribosyl-ATP diphosphatase activity
CEK71_RS06880	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CEK71_RS06890	COG0107	imidazoleglycerol-phosphate synthase activity
CEK71_RS06905	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CEK71_RS06910	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CEK71_RS06915	COG0131	Imidazoleglycerol-phosphate dehydratase
CEK71_RS06925	COG1217	gtp-binding protein TYPA
CEK71_RS06935	COG0583	DNA-binding transcription factor activity
CEK71_RS06945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEK71_RS06995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEK71_RS07000	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEK71_RS07005	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CEK71_RS07010	COG3300	MHYT domain
CEK71_RS07010	COG5001	Diguanylate cyclase
CEK71_RS07015	COG2409	Drug exporters of the RND superfamily
CEK71_RS07035	COG2801	Transposase and inactivated derivatives
CEK71_RS07085	COG4302	ethanolamine ammonia-lyase activity
CEK71_RS07095	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CEK71_RS07100	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CEK71_RS07110	COG1309	transcriptional regulator
CEK71_RS07125	COG1566	PFAM secretion protein HlyD family protein
CEK71_RS07135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEK71_RS07160	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CEK71_RS07165	COG0778	Nitroreductase
CEK71_RS07215	COG1891	lyase activity
CEK71_RS07220	COG0542	response to heat
CEK71_RS07245	COG2307	Protein conserved in bacteria
CEK71_RS07245	COG2308	Evidence 4 Homologs of previously reported genes of
CEK71_RS07255	COG2223	nitrite transmembrane transporter activity
CEK71_RS07280	COG0181	hydroxymethylbilane synthase activity
CEK71_RS07285	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CEK71_RS07290	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CEK71_RS07295	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CEK71_RS07300	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEK71_RS07305	COG0617	tRNA 3'-terminal CCA addition
CEK71_RS07320	COG0339	signal peptide processing
CEK71_RS07325	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CEK71_RS07350	COG0604	alcohol dehydrogenase
CEK71_RS07350	COG3321	synthase
CEK71_RS07350	COG1028	Short-chain dehydrogenase reductase Sdr
CEK71_RS07355	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CEK71_RS07385	COG0415	Belongs to the DNA photolyase family
CEK71_RS07390	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CEK71_RS07450	COG2815	serine threonine protein kinase
CEK71_RS07450	COG0515	serine threonine protein kinase
CEK71_RS07505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEK71_RS07515	COG2350	Protein conserved in bacteria
CEK71_RS07535	COG1420	regulation of RNA biosynthetic process
CEK71_RS07540	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CEK71_RS07545	COG0443	Heat shock 70 kDa protein
CEK71_RS07555	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEK71_RS07565	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CEK71_RS07570	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CEK71_RS07580	COG1053	succinate dehydrogenase
CEK71_RS07585	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CEK71_RS07595	COG3852	Histidine kinase
CEK71_RS07600	COG2204	response regulator
CEK71_RS07625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEK71_RS07625	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEK71_RS07645	COG2161	toxin-antitoxin pair type II binding
CEK71_RS07650	COG2878	Part of a membrane complex involved in electron transport
CEK71_RS07655	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEK71_RS07660	COG2813	Specifically methylates the guanine in position
CEK71_RS07665	COG1278	Cold shock
CEK71_RS07670	COG2154	pterin-4-alpha-carbinolamine dehydratase
CEK71_RS07675	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CEK71_RS07680	COG0484	heat shock protein binding
CEK71_RS07685	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CEK71_RS07690	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CEK71_RS07705	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CEK71_RS07710	COG3383	formate dehydrogenase (NAD+) activity
CEK71_RS07750	COG0631	protein serine/threonine phosphatase activity
CEK71_RS07755	COG2815	serine threonine protein kinase
CEK71_RS07755	COG0515	serine threonine protein kinase
CEK71_RS07770	COG0316	Belongs to the HesB IscA family
CEK71_RS07775	COG1104	cysteine desulfurase activity
CEK71_RS07780	COG1959	2 iron, 2 sulfur cluster binding
CEK71_RS07805	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEK71_RS07830	COG4178	(ABC) transporter
CEK71_RS07835	COG1773	rubredoxin
CEK71_RS07855	COG0495	leucyl-tRNA aminoacylation
CEK71_RS07860	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CEK71_RS07865	COG1466	dna polymerase III delta subunit
CEK71_RS07885	COG0101	tRNA pseudouridine synthase activity
CEK71_RS07890	COG1215	transferase activity, transferring glycosyl groups
CEK71_RS07900	COG1045	serine acetyltransferase
CEK71_RS07910	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEK71_RS07945	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CEK71_RS07955	COG0714	Associated with various cellular activities
CEK71_RS07970	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CEK71_RS07975	COG4149	molybdate abc transporter
CEK71_RS07980	COG0725	ABC transporter, periplasmic molybdate-binding protein
CEK71_RS08020	COG1082	Xylose isomerase domain protein TIM barrel
CEK71_RS08060	COG4657	Part of a membrane complex involved in electron transport
CEK71_RS08065	COG2878	Part of a membrane complex involved in electron transport
CEK71_RS08070	COG4656	Part of a membrane complex involved in electron transport
CEK71_RS08075	COG4658	electron transport chain
CEK71_RS08090	COG2914	Belongs to the UPF0125 (RnfH) family
CEK71_RS08095	COG2010	Cytochrome c
CEK71_RS08105	COG0688	phosphatidylethanolamine metabolic process
CEK71_RS08115	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CEK71_RS08140	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CEK71_RS08145	COG1902	pentaerythritol trinitrate reductase activity
CEK71_RS08180	COG0583	DNA-binding transcription factor activity
CEK71_RS08190	COG0288	reversible hydration of carbon dioxide
CEK71_RS08200	COG1366	Belongs to the anti-sigma-factor antagonist family
CEK71_RS08225	COG5002	protein histidine kinase activity
CEK71_RS08230	COG2770	Histidine kinase
CEK71_RS08230	COG2208	phosphoserine phosphatase activity
CEK71_RS08275	COG3094	Invasion gene expression up-regulator, SirB
CEK71_RS08280	COG3001	Fructosamine kinase
CEK71_RS08290	COG0730	response to heat
CEK71_RS08295	COG0583	DNA-binding transcription factor activity
CEK71_RS08340	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CEK71_RS08360	COG1192	Involved in chromosome partitioning
CEK71_RS08365	COG2239	Acts as a magnesium transporter
CEK71_RS08370	COG4453	Protein conserved in bacteria
CEK71_RS08385	COG0529	Catalyzes the synthesis of activated sulfate
CEK71_RS08405	COG0494	nUDIX hydrolase
CEK71_RS08410	COG0791	NLP P60 protein
CEK71_RS08425	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CEK71_RS08460	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CEK71_RS08475	COG4456	Virulence-associated protein
CEK71_RS08495	COG1301	dicarboxylic acid transport
CEK71_RS08500	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CEK71_RS08515	COG2091	lysine biosynthetic process via aminoadipic acid
CEK71_RS08525	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEK71_RS08530	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CEK71_RS08560	COG0585	pseudouridine synthase activity
CEK71_RS08570	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CEK71_RS08575	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CEK71_RS08585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEK71_RS08600	COG1309	transcriptional regulator
CEK71_RS08605	COG3550	peptidyl-serine autophosphorylation
CEK71_RS08645	COG4106	trans-aconitate 2-methyltransferase activity
CEK71_RS08660	COG0501	Belongs to the peptidase M48B family
CEK71_RS08665	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CEK71_RS08670	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CEK71_RS08705	COG3541	Predicted nucleotidyltransferase
CEK71_RS08750	COG0659	secondary active sulfate transmembrane transporter activity
CEK71_RS08755	COG0659	secondary active sulfate transmembrane transporter activity
CEK71_RS08760	COG0745	RESPONSE REGULATOR receiver
CEK71_RS08770	COG1376	ErfK ybiS ycfS ynhG family protein
CEK71_RS08775	COG0531	amino acid
CEK71_RS08815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEK71_RS08850	COG0653	protein targeting
CEK71_RS08865	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CEK71_RS08895	COG0408	coproporphyrinogen oxidase activity
CEK71_RS08905	COG0135	phosphoribosylanthranilate isomerase activity
CEK71_RS08910	COG0133	tryptophan synthase activity
CEK71_RS08915	COG0159	tryptophan synthase activity
CEK71_RS08920	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CEK71_RS08925	COG0285	dihydrofolate synthase activity
CEK71_RS08965	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CEK71_RS08985	COG0732	type I restriction modification DNA specificity domain
CEK71_RS09010	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CEK71_RS09045	COG3561	AntA/AntB antirepressor
CEK71_RS09085	COG0110	maltose O-acetyltransferase activity
CEK71_RS09140	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CEK71_RS09145	COG2183	response to ionizing radiation
CEK71_RS09165	COG1049	propionate catabolic process, 2-methylcitrate cycle
CEK71_RS09200	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CEK71_RS09205	COG0708	Exodeoxyribonuclease III
CEK71_RS09210	COG0254	rRNA binding
CEK71_RS09235	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CEK71_RS09240	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CEK71_RS09245	COG0537	adenosine 5'-monophosphoramidase activity
CEK71_RS09255	COG1805	sodium ion transport
CEK71_RS09270	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CEK71_RS09275	COG2871	sodium ion transport
CEK71_RS09295	COG2925	Exonuclease
CEK71_RS09300	COG2951	lytic endotransglycosylase activity
CEK71_RS09305	COG0028	Belongs to the TPP enzyme family
CEK71_RS09315	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CEK71_RS09355	COG0840	transmembrane signaling receptor activity
CEK71_RS09375	COG1477	protein flavinylation
CEK71_RS09400	COG0601	transmembrane transport
CEK71_RS09495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEK71_RS09505	COG2204	response regulator
CEK71_RS09515	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CEK71_RS09565	COG0009	L-threonylcarbamoyladenylate synthase
CEK71_RS09570	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CEK71_RS09585	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CEK71_RS09595	COG1160	GTP binding
CEK71_RS09600	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEK71_RS09615	COG0124	histidyl-tRNA synthetase
CEK71_RS09625	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CEK71_RS09630	COG0105	UTP biosynthetic process
CEK71_RS09635	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEK71_RS09640	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEK71_RS09645	COG1862	Preprotein translocase
CEK71_RS09650	COG3739	integral membrane protein
CEK71_RS09660	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CEK71_RS09675	COG0678	peroxiredoxin activity
CEK71_RS09705	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CEK71_RS09710	COG0076	glutamate decarboxylase activity
CEK71_RS09715	COG4774	siderophore transport
CEK71_RS09735	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CEK71_RS09740	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CEK71_RS09750	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CEK71_RS09755	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CEK71_RS09765	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEK71_RS09770	COG0312	modulator of DNA gyrase
CEK71_RS09780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEK71_RS09790	COG1530	ribonuclease E activity
CEK71_RS09795	COG0424	maF-like protein
CEK71_RS09800	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CEK71_RS09815	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CEK71_RS09830	COG2801	Transposase and inactivated derivatives
CEK71_RS09930	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CEK71_RS09945	COG1196	nuclear chromosome segregation
CEK71_RS09985	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CEK71_RS09985	COG0784	Response regulator, receiver
CEK71_RS10075	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CEK71_RS10085	COG1518	maintenance of DNA repeat elements
CEK71_RS10085	COG1468	defense response to virus
CEK71_RS10090	COG3344	reverse transcriptase
CEK71_RS10100	COG1074	ATP-dependent DNA helicase activity
CEK71_RS10110	COG3339	Conserved Protein
CEK71_RS10120	COG2801	Transposase and inactivated derivatives
CEK71_RS10140	COG1131	(ABC) transporter
CEK71_RS10145	COG0842	Transport permease protein
CEK71_RS10150	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CEK71_RS10165	COG0456	acetyltransferase
CEK71_RS10170	COG0686	Belongs to the AlaDH PNT family
CEK71_RS10175	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CEK71_RS10180	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEK71_RS10195	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CEK71_RS10205	COG2264	protein methyltransferase activity
CEK71_RS10210	COG0439	Biotin carboxylase
CEK71_RS10215	COG0511	ligase activity, forming carbon-carbon bonds
CEK71_RS10220	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CEK71_RS10225	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEK71_RS10230	COG0546	phosphoglycolate phosphatase activity
CEK71_RS10235	COG1028	Short-chain dehydrogenase reductase Sdr
CEK71_RS10240	COG2151	metal-sulfur cluster biosynthetic enzyme
CEK71_RS10245	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CEK71_RS10250	COG1472	Belongs to the glycosyl hydrolase 3 family
CEK71_RS10255	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CEK71_RS10260	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CEK71_RS10275	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CEK71_RS10285	COG3220	belongs to the UPF0276 family
CEK71_RS10295	COG0167	dihydroorotate dehydrogenase activity
CEK71_RS10315	COG4115	mRNA cleavage
CEK71_RS10330	COG4783	chaperone-mediated protein folding
CEK71_RS10335	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CEK71_RS10355	COG0110	maltose O-acetyltransferase activity
CEK71_RS10365	COG4191	Histidine kinase
CEK71_RS10365	COG0784	Response regulator, receiver
CEK71_RS10380	COG0438	transferase activity, transferring glycosyl groups
CEK71_RS10405	COG0598	Magnesium transport protein CorA
CEK71_RS10450	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEK71_RS10475	COG0315	cyclic pyranopterin monophosphate synthase activity
CEK71_RS10480	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CEK71_RS10485	COG0314	molybdopterin synthase activity
CEK71_RS10525	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CEK71_RS10540	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CEK71_RS10560	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CEK71_RS10570	COG0488	(ABC) transporter
CEK71_RS10585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEK71_RS10595	COG0004	ammonium transporteR
CEK71_RS10600	COG0347	Belongs to the P(II) protein family
CEK71_RS10615	COG0174	glutamine synthetase
CEK71_RS10625	COG3852	Histidine kinase
CEK71_RS10630	COG2204	response regulator
CEK71_RS10640	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CEK71_RS10645	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CEK71_RS10660	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CEK71_RS10665	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CEK71_RS10670	COG1032	radical SAM domain protein
CEK71_RS10680	COG3008	intermembrane lipid transfer
CEK71_RS10680	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CEK71_RS10685	COG2995	paraquat-inducible protein a
CEK71_RS10690	COG2995	paraquat-inducible protein a
CEK71_RS10695	COG2217	Heavy metal translocating P-type atpase
CEK71_RS10705	COG2915	High frequency lysogenization protein hflD homolog
CEK71_RS10725	COG0039	L-malate dehydrogenase activity
CEK71_RS10730	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CEK71_RS10735	COG2379	hydroxypyruvate reductase
CEK71_RS10740	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CEK71_RS10750	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CEK71_RS10755	COG0569	domain protein
CEK71_RS10760	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CEK71_RS10805	COG0811	peptide transport
CEK71_RS10840	COG1511	domain protein
CEK71_RS10840	COG3264	Mechanosensitive ion channel
CEK71_RS10845	COG0436	Aminotransferase
CEK71_RS10875	COG4774	siderophore transport
CEK71_RS10885	COG3128	pkhd-type hydroxylase
CEK71_RS10895	COG0519	Catalyzes the synthesis of GMP from XMP
CEK71_RS10895	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CEK71_RS10910	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CEK71_RS10920	COG4804	nuclease activity
CEK71_RS10980	COG1393	Belongs to the ArsC family
CEK71_RS10985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEK71_RS11000	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CEK71_RS11005	COG1473	amidohydrolase
CEK71_RS11010	COG1671	Belongs to the UPF0178 family
CEK71_RS11020	COG2715	membrane protein required for spore maturation
CEK71_RS11030	COG1530	ribonuclease E activity
CEK71_RS11035	COG0564	pseudouridine synthase activity
CEK71_RS11040	COG0546	phosphoglycolate phosphatase activity
CEK71_RS11065	COG1902	pentaerythritol trinitrate reductase activity
CEK71_RS11075	COG0837	glucose binding
CEK71_RS11100	COG0739	heme binding
CEK71_RS11105	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CEK71_RS11110	COG0316	Belongs to the HesB IscA family
CEK71_RS11115	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CEK71_RS11130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEK71_RS11190	COG1657	PFAM Prenyltransferase squalene oxidase
CEK71_RS11220	COG3829	transcription factor binding
CEK71_RS11235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEK71_RS11250	COG5002	protein histidine kinase activity
CEK71_RS11250	COG2205	protein histidine kinase activity
CEK71_RS11250	COG0784	Response regulator, receiver
CEK71_RS11255	COG5002	protein histidine kinase activity
CEK71_RS11255	COG0784	Response regulator, receiver
CEK71_RS11265	COG0431	NADPH-dependent FMN reductase
CEK71_RS11305	COG2823	Periplasmic or secreted lipoprotein
CEK71_RS11360	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CEK71_RS11390	COG1797	cobyrinic acid a,c-diamide synthase activity
CEK71_RS11400	COG1492	cobalamin metabolic process
CEK71_RS11405	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CEK71_RS11410	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CEK71_RS11415	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CEK71_RS11445	COG1028	Short-chain dehydrogenase reductase Sdr
CEK71_RS11450	COG1012	belongs to the aldehyde dehydrogenase family
CEK71_RS11485	COG1215	transferase activity, transferring glycosyl groups
CEK71_RS11490	COG1216	Glycosyl transferase, family 2
CEK71_RS11495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEK71_RS11500	COG0109	protoheme IX farnesyltransferase activity
CEK71_RS11530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEK71_RS11530	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CEK71_RS11540	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CEK71_RS11550	COG1598	PFAM Uncharacterised protein family UPF0150
CEK71_RS11660	COG2274	protein secretion by the type I secretion system
CEK71_RS11665	COG2274	protein secretion by the type I secretion system
CEK71_RS11670	COG0129	dihydroxy-acid dehydratase activity
CEK71_RS11685	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CEK71_RS11690	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CEK71_RS11705	COG0242	peptide deformylase activity
CEK71_RS11720	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CEK71_RS11725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEK71_RS11745	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CEK71_RS11770	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CEK71_RS11785	COG4181	ATPase activity
CEK71_RS11805	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CEK71_RS11815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CEK71_RS11825	COG0535	radical SAM domain protein
CEK71_RS11830	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CEK71_RS11835	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CEK71_RS11835	COG2755	lipolytic protein G-D-S-L family
CEK71_RS11845	COG0312	modulator of DNA gyrase
CEK71_RS11855	COG2815	serine threonine protein kinase
CEK71_RS11855	COG0515	serine threonine protein kinase
CEK71_RS11865	COG2815	serine threonine protein kinase
CEK71_RS11865	COG0515	serine threonine protein kinase
CEK71_RS11870	COG1716	ATPase activity
CEK71_RS11885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEK71_RS11890	COG4628	conserved protein (DUF2132)
CEK71_RS11900	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CEK71_RS11930	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CEK71_RS11935	COG2921	Belongs to the UPF0250 family
CEK71_RS11945	COG1686	Belongs to the peptidase S11 family
CEK71_RS11955	COG2951	lytic endotransglycosylase activity
CEK71_RS11960	COG0772	Belongs to the SEDS family
CEK71_RS11975	COG1301	dicarboxylic acid transport
CEK71_RS11980	COG0443	Heat shock 70 kDa protein
CEK71_RS11985	COG3706	GGDEF domain
CEK71_RS12030	COG1074	ATP-dependent DNA helicase activity
CEK71_RS12070	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CEK71_RS12095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEK71_RS12095	COG0425	Belongs to the sulfur carrier protein TusA family
CEK71_RS12105	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CEK71_RS12115	COG1994	Peptidase M50
CEK71_RS12120	COG0009	L-threonylcarbamoyladenylate synthase
CEK71_RS12140	COG0776	regulation of translation
CEK71_RS12150	COG0535	radical SAM domain protein
CEK71_RS12185	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CEK71_RS12195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEK71_RS12200	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CEK71_RS12210	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CEK71_RS12240	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEK71_RS12245	COG0302	gtp cyclohydrolase
CEK71_RS12250	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CEK71_RS12255	COG3012	SEC-C Motif Domain Protein
CEK71_RS12265	COG0644	oxidoreductase
CEK71_RS12285	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CEK71_RS12290	COG0129	dihydroxy-acid dehydratase activity
CEK71_RS12295	COG3738	Protein conserved in bacteria
CEK71_RS12300	COG0800	Aldolase
CEK71_RS12305	COG0372	Belongs to the citrate synthase family
CEK71_RS12325	COG0784	Response regulator, receiver
CEK71_RS12325	COG2205	protein histidine kinase activity
CEK71_RS12325	COG5002	protein histidine kinase activity
CEK71_RS12350	COG0450	alkyl hydroperoxide reductase
CEK71_RS12355	COG0308	aminopeptidase N
CEK71_RS12360	COG2363	Small membrane protein
CEK71_RS12365	COG0521	Mo-molybdopterin cofactor biosynthetic process
CEK71_RS12370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEK71_RS12390	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CEK71_RS12420	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CEK71_RS12435	COG4993	Dehydrogenase
CEK71_RS12445	COG2010	Cytochrome c
CEK71_RS12455	COG0714	Associated with various cellular activities
CEK71_RS12515	COG0746	molybdenum cofactor guanylyltransferase activity
CEK71_RS12530	COG0189	ligase activity
CEK71_RS12530	COG4067	protein conserved in archaea
CEK71_RS12535	COG2827	Endonuclease containing a URI domain
CEK71_RS12540	COG0037	tRNA processing
CEK71_RS12550	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEK71_RS12555	COG0741	lytic transglycosylase activity
CEK71_RS12565	COG1196	nuclear chromosome segregation
CEK71_RS12575	COG1566	PFAM secretion protein HlyD family protein
CEK71_RS12585	COG2814	Major facilitator Superfamily
CEK71_RS12590	COG3604	Transcriptional regulator
CEK71_RS12605	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CEK71_RS12615	COG4974	Belongs to the 'phage' integrase family
CEK71_RS12620	COG1785	Belongs to the alkaline phosphatase family
CEK71_RS12635	COG2226	methyltransferase
CEK71_RS12690	COG0277	FAD linked oxidase domain protein
CEK71_RS12700	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CEK71_RS12705	COG0792	nuclease activity
CEK71_RS12710	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CEK71_RS12720	COG2001	Belongs to the MraZ family
CEK71_RS12725	COG0275	rRNA processing
CEK71_RS12745	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CEK71_RS12750	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEK71_RS12755	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CEK71_RS12760	COG0772	Belongs to the SEDS family
CEK71_RS12765	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CEK71_RS12770	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEK71_RS12775	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CEK71_RS12780	COG1181	Belongs to the D-alanine--D-alanine ligase family
CEK71_RS12785	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CEK71_RS12840	COG1538	Outer membrane efflux protein
CEK71_RS12860	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CEK71_RS12865	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CEK71_RS12895	COG0493	'glutamate synthase
CEK71_RS12895	COG0543	2 iron, 2 sulfur cluster binding
CEK71_RS12915	COG1067	ATP-dependent peptidase activity
CEK71_RS12925	COG4636	protein conserved in cyanobacteria
CEK71_RS12940	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CEK71_RS12960	COG1858	cytochrome C peroxidase
CEK71_RS12970	COG2010	Cytochrome c
CEK71_RS13080	COG2226	methyltransferase
CEK71_RS13090	COG5001	Diguanylate cyclase
CEK71_RS13090	COG5002	protein histidine kinase activity
CEK71_RS13100	COG1362	aminopeptidase activity
CEK71_RS13105	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEK71_RS13110	COG3002	Belongs to the UPF0753 family
CEK71_RS13115	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CEK71_RS13135	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEK71_RS13140	COG0134	indole-3-glycerol-phosphate synthase activity
CEK71_RS13155	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CEK71_RS13155	COG0519	Catalyzes the synthesis of GMP from XMP
CEK71_RS13165	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEK71_RS13175	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CEK71_RS13180	COG0384	phenazine biosynthesis protein PhzF
CEK71_RS13185	COG2146	nitrite reductase [NAD(P)H] activity
CEK71_RS13190	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CEK71_RS13200	COG0151	Belongs to the GarS family
CEK71_RS13205	COG0138	bifunctional purine biosynthesis protein purh
CEK71_RS13220	COG0019	diaminopimelate decarboxylase activity
CEK71_RS13230	COG1116	anion transmembrane transporter activity
CEK71_RS13230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CEK71_RS13240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CEK71_RS13245	COG0583	DNA-binding transcription factor activity
CEK71_RS13255	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CEK71_RS13260	COG4208	sulfate ABC transporter
CEK71_RS13265	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CEK71_RS13270	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CEK71_RS13300	COG2204	response regulator
CEK71_RS13305	COG0084	hydrolase, TatD family'
CEK71_RS13310	COG3573	Dehydrogenase
CEK71_RS13365	COG0509	glycine decarboxylation via glycine cleavage system
CEK71_RS13370	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CEK71_RS13375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEK71_RS13380	COG3956	TIGRFAM MazG family protein
CEK71_RS13385	COG5433	transposase activity
CEK71_RS13520	COG4373	Mu-like prophage FluMu protein gp28
CEK71_RS13540	COG1876	peptidase activity
CEK71_RS13640	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEK71_RS13650	COG0243	molybdopterin cofactor binding
CEK71_RS13675	COG2197	response regulator
CEK71_RS13690	COG0243	molybdopterin cofactor binding
CEK71_RS13705	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CEK71_RS13710	COG2204	response regulator
CEK71_RS13715	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CEK71_RS13730	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEK71_RS13740	COG2922	Belongs to the Smg family
CEK71_RS13745	COG0758	DNA mediated transformation
CEK71_RS13755	COG0242	peptide deformylase activity
CEK71_RS13760	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CEK71_RS13775	COG5000	phosphorelay sensor kinase activity
CEK71_RS13780	COG2204	response regulator
CEK71_RS13785	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CEK71_RS13790	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CEK71_RS13795	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CEK71_RS13820	COG0735	belongs to the Fur family
CEK71_RS13835	COG3158	transport of potassium into the cell
CEK71_RS13845	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CEK71_RS13845	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEK71_RS13850	COG1127	ABC transporter
CEK71_RS13860	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CEK71_RS13875	COG1137	ATPase activity
CEK71_RS13890	COG1660	Displays ATPase and GTPase activities
CEK71_RS13900	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CEK71_RS13905	COG2894	cell division
CEK71_RS13910	COG0850	regulation of cytokinetic process
CEK71_RS13955	COG2326	polyphosphate kinase activity
CEK71_RS13960	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CEK71_RS13965	COG1127	ABC transporter
CEK71_RS13995	COG0513	Belongs to the DEAD box helicase family
CEK71_RS14035	COG5622	Protein required for attachment to host cells
CEK71_RS14040	COG0789	Transcriptional regulator
CEK71_RS14100	COG3459	Glycosyltransferase 36 associated
CEK71_RS14105	COG0500	methyltransferase
CEK71_RS14115	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CEK71_RS14120	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CEK71_RS14125	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CEK71_RS14135	COG0356	it plays a direct role in the translocation of protons across the membrane
CEK71_RS14155	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CEK71_RS14190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEK71_RS14200	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CEK71_RS14205	COG0165	Argininosuccinate lyase
CEK71_RS14220	COG0671	phosphoesterase, PA-phosphatase related
CEK71_RS14260	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CEK71_RS14270	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CEK71_RS14305	COG4566	intracellular signal transduction
CEK71_RS14340	COG2197	response regulator
CEK71_RS14395	COG0149	triose-phosphate isomerase activity
CEK71_RS14400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEK71_RS14410	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CEK71_RS14420	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEK71_RS14425	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CEK71_RS14440	COG0505	Belongs to the CarA family
CEK71_RS14445	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CEK71_RS14460	COG1923	regulation of RNA biosynthetic process
CEK71_RS14465	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CEK71_RS14470	COG0330	HflC and HflK could
CEK71_RS14475	COG0330	HflC and HflK could
CEK71_RS14480	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CEK71_RS14485	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CEK71_RS14490	COG1185	polyribonucleotide nucleotidyltransferase activity
CEK71_RS14495	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CEK71_RS14500	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CEK71_RS14515	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CEK71_RS14520	COG2251	uridine kinase activity
CEK71_RS14520	COG0195	Participates in both transcription termination and antitermination
CEK71_RS14525	COG0779	Required for maturation of 30S ribosomal subunits
CEK71_RS14535	COG1573	uracil-dna glycosylase
CEK71_RS14550	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEK71_RS14585	COG1518	maintenance of DNA repeat elements
CEK71_RS14595	COG5002	protein histidine kinase activity
CEK71_RS14605	COG2205	protein histidine kinase activity
CEK71_RS14615	COG4942	peptidase
CEK71_RS14625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CEK71_RS14640	COG2205	protein histidine kinase activity
CEK71_RS14645	COG0745	RESPONSE REGULATOR receiver
CEK71_RS14655	COG2132	Multicopper oxidase
CEK71_RS14660	COG0247	lactate metabolic process
CEK71_RS14700	COG2824	Alkylphosphonate utilization operon protein PhnA
CEK71_RS14715	COG0633	Ferredoxin
CEK71_RS14720	COG0426	domain, Protein
CEK71_RS14765	COG0640	Transcriptional regulator
CEK71_RS14770	COG1028	Short-chain dehydrogenase reductase Sdr
CEK71_RS14775	COG3335	DDE superfamily endonuclease
CEK71_RS14785	COG0284	orotidine-5'-phosphate decarboxylase activity
CEK71_RS14830	COG1136	(ABC) transporter
CEK71_RS14835	COG1136	(ABC) transporter
CEK71_RS14835	COG0577	efflux transmembrane transporter activity
CEK71_RS14875	COG1472	Belongs to the glycosyl hydrolase 3 family
CEK71_RS14885	COG4636	protein conserved in cyanobacteria
CEK71_RS14925	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CEK71_RS14935	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CEK71_RS14940	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CEK71_RS14945	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEK71_RS14950	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEK71_RS14960	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEK71_RS14965	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CEK71_RS14970	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEK71_RS14975	COG1509	lysine 2,3-aminomutase activity
CEK71_RS14980	COG1555	photosystem II stabilization
CEK71_RS15015	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CEK71_RS15025	COG4536	flavin adenine dinucleotide binding
CEK71_RS15030	COG0360	Binds together with S18 to 16S ribosomal RNA
CEK71_RS15035	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CEK71_RS15045	COG0359	binds to the 23S rRNA
CEK71_RS15050	COG1519	Transferase
CEK71_RS15055	COG2814	Major facilitator Superfamily
CEK71_RS15065	COG3153	acetyltransferase
CEK71_RS15065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEK71_RS15145	COG1064	alcohol dehydrogenase
CEK71_RS15150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEK71_RS15155	COG2854	intermembrane phospholipid transfer
CEK71_RS15165	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CEK71_RS15175	COG0217	transcriptional regulatory protein
CEK71_RS15185	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CEK71_RS15185	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CEK71_RS15235	COG1192	Involved in chromosome partitioning
CEK71_RS15240	COG1475	DNA binding
CEK71_RS15245	COG1136	(ABC) transporter
CEK71_RS15245	COG0577	efflux transmembrane transporter activity
CEK71_RS15250	COG0577	efflux transmembrane transporter activity
CEK71_RS15250	COG1136	(ABC) transporter
CEK71_RS15255	COG1566	PFAM secretion protein HlyD family protein
CEK71_RS15305	COG2095	MarC family integral membrane protein
CEK71_RS15310	COG0753	catalase activity
CEK71_RS15355	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CEK71_RS15370	COG0557	exoribonuclease II activity
CEK71_RS15375	COG0513	Belongs to the DEAD box helicase family
CEK71_RS15380	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CEK71_RS15385	COG3122	Protein conserved in bacteria
CEK71_RS15390	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CEK71_RS15410	COG1722	exodeoxyribonuclease VII activity
CEK71_RS15415	COG0142	geranyltranstransferase activity
CEK71_RS15455	COG1196	nuclear chromosome segregation
CEK71_RS15470	COG0004	ammonium transporteR
CEK71_RS15485	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CEK71_RS15505	COG4206	TonB-dependent receptor
CEK71_RS15520	COG0058	SHG alpha-glucan phosphorylase activity
CEK71_RS15525	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CEK71_RS15530	COG0556	nucleotide-excision repair
CEK71_RS15555	COG0469	pyruvate kinase activity
CEK71_RS15560	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEK71_RS15570	COG2198	Histidine kinase
CEK71_RS15570	COG0643	Histidine kinase
CEK71_RS15590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEK71_RS15600	COG0126	phosphoglycerate kinase activity
CEK71_RS15610	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
CEK71_RS15635	COG0443	Heat shock 70 kDa protein
CEK71_RS15670	COG0840	transmembrane signaling receptor activity
CEK71_RS15690	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CEK71_RS15715	COG2890	protein-(glutamine-N5) methyltransferase activity
CEK71_RS15720	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CEK71_RS15725	COG0488	(ABC) transporter
CEK71_RS15735	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CEK71_RS15740	COG0714	Associated with various cellular activities
CEK71_RS15755	COG2304	oxidoreductase activity
CEK71_RS15760	COG2304	oxidoreductase activity
CEK71_RS15765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEK71_RS15770	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEK71_RS15810	COG1538	Outer membrane efflux protein
CEK71_RS15825	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CEK71_RS15865	COG0137	argininosuccinate synthase activity
CEK71_RS15875	COG0326	Molecular chaperone. Has ATPase activity
CEK71_RS15905	COG0436	Aminotransferase
CEK71_RS15920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEK71_RS16010	COG1605	Chorismate mutase
CEK71_RS16015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEK71_RS16045	COG0776	regulation of translation
CEK71_RS16055	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CEK71_RS16065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEK71_RS16075	COG1605	Chorismate mutase
CEK71_RS16075	COG0077	Prephenate dehydratase
CEK71_RS16080	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CEK71_RS16105	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CEK71_RS16125	COG2226	methyltransferase
CEK71_RS16140	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CEK71_RS16155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CEK71_RS16165	COG2373	Large extracellular alpha-helical protein
CEK71_RS16170	COG4953	penicillin-binding protein 1C
CEK71_RS16180	COG0653	protein targeting
CEK71_RS16190	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEK71_RS16220	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CEK71_RS16235	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CEK71_RS16240	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CEK71_RS16275	COG0004	ammonium transporteR
CEK71_RS16280	COG0347	Belongs to the P(II) protein family
CEK71_RS16290	COG2259	Doxx family
CEK71_RS16330	COG2801	Transposase and inactivated derivatives
CEK71_RS16370	COG0745	RESPONSE REGULATOR receiver
CEK71_RS16390	COG3012	SEC-C Motif Domain Protein
CEK71_RS16400	COG1372	Participates in initiation and elongation during chromosome replication
CEK71_RS16400	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEK71_RS16410	COG4453	Protein conserved in bacteria
CEK71_RS16420	COG0390	transport system, permease component
CEK71_RS16485	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CEK71_RS16520	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CEK71_RS16525	COG0067	glutamate synthase
CEK71_RS16525	COG0069	glutamate synthase activity
CEK71_RS16525	COG0070	glutamate synthase
CEK71_RS16530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEK71_RS16545	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CEK71_RS16550	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CEK71_RS16555	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CEK71_RS16565	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CEK71_RS16570	COG0072	phenylalanine-tRNA ligase activity
CEK71_RS16570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEK71_RS16600	COG3447	MASE1 domain protein
CEK71_RS16600	COG5001	Diguanylate cyclase
CEK71_RS16600	COG5002	protein histidine kinase activity
CEK71_RS16615	COG3119	arylsulfatase activity
CEK71_RS16620	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CEK71_RS16645	COG1730	sister chromatid segregation
CEK71_RS16670	COG0045	succinate-CoA ligase (ADP-forming) activity
CEK71_RS16675	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CEK71_RS16695	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CEK71_RS16695	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CEK71_RS16705	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEK71_RS16710	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CEK71_RS16725	COG1301	dicarboxylic acid transport
CEK71_RS16735	COG4456	Virulence-associated protein
CEK71_RS16740	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CEK71_RS16745	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CEK71_RS16765	COG0540	Belongs to the ATCase OTCase family
CEK71_RS16770	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CEK71_RS16785	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CEK71_RS16790	COG1678	Uncharacterized ACR, COG1678
CEK71_RS16805	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CEK71_RS16810	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEK71_RS16815	COG2308	Evidence 4 Homologs of previously reported genes of
CEK71_RS16935	COG0322	excinuclease ABC activity
CEK71_RS16940	COG2914	Belongs to the UPF0125 (RnfH) family
CEK71_RS16945	COG2867	negative regulation of translational initiation
CEK71_RS16950	COG0733	neurotransmitter:sodium symporter activity
CEK71_RS16955	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CEK71_RS16960	COG1335	isochorismatase
CEK71_RS16975	COG4191	Histidine kinase
CEK71_RS17010	COG0745	RESPONSE REGULATOR receiver
CEK71_RS17015	COG5001	Diguanylate cyclase
CEK71_RS17015	COG4251	negative regulation of phosphorylation
CEK71_RS17015	COG3706	GGDEF domain
CEK71_RS17015	COG2203	Gaf domain
CEK71_RS17115	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CEK71_RS17155	COG0416	fatty acid biosynthetic process
CEK71_RS17160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEK71_RS17170	COG1028	Short-chain dehydrogenase reductase Sdr
CEK71_RS17175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEK71_RS17190	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CEK71_RS17195	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CEK71_RS17215	COG4191	Histidine kinase
CEK71_RS17245	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CEK71_RS17255	COG0501	Belongs to the peptidase M48B family
CEK71_RS17395	COG4636	protein conserved in cyanobacteria
CEK71_RS17400	COG1132	(ABC) transporter
CEK71_RS17420	COG0488	(ABC) transporter
CEK71_RS17445	COG0488	(ABC) transporter
CEK71_RS17485	COG3034	peptidoglycan biosynthetic process
CEK71_RS17500	COG4221	oxidoreductase activity
CEK71_RS17510	COG1028	Short-chain dehydrogenase reductase Sdr
CEK71_RS17515	COG1733	regulation of RNA biosynthetic process
CEK71_RS17530	COG0194	GDP metabolic process
CEK71_RS17535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CEK71_RS17555	COG1136	(ABC) transporter
CEK71_RS17555	COG0577	efflux transmembrane transporter activity
CEK71_RS17560	COG1136	(ABC) transporter
CEK71_RS17560	COG0577	efflux transmembrane transporter activity
CEK71_RS17580	COG0745	RESPONSE REGULATOR receiver
CEK71_RS17585	COG2205	protein histidine kinase activity
CEK71_RS17595	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CEK71_RS17600	COG2954	triphosphatase activity
CEK71_RS17610	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CEK71_RS17620	COG1090	epimerase
CEK71_RS17640	COG2020	methyltransferase activity
CEK71_RS17650	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CEK71_RS17655	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CEK71_RS17760	COG0732	type I restriction modification DNA specificity domain
CEK71_RS17825	COG1192	Involved in chromosome partitioning
CEK71_RS17845	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CEK71_RS17850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CEK71_RS17890	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CEK71_RS17900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEK71_RS17915	COG2900	Belongs to the SlyX family
CEK71_RS17935	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CEK71_RS17940	COG2967	ApaG domain
CEK71_RS17945	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CEK71_RS17960	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CEK71_RS17965	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEK71_RS17980	COG2833	Protein of unknown function (DUF455)
CEK71_RS17995	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CEK71_RS18005	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CEK71_RS18030	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CEK71_RS18040	COG0045	succinate-CoA ligase (ADP-forming) activity
CEK71_RS18045	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CEK71_RS18065	COG4636	protein conserved in cyanobacteria
CEK71_RS18095	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEK71_RS18105	COG0215	cysteine-tRNA ligase activity
CEK71_RS18110	COG3404	Formiminotransferase-cyclodeaminase
CEK71_RS18125	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CEK71_RS18215	COG0582	viral genome integration into host DNA
CEK71_RS18235	COG1254	Belongs to the acylphosphatase family
CEK71_RS18240	COG0116	Belongs to the methyltransferase superfamily
CEK71_RS18240	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CEK71_RS18245	COG0545	Peptidyl-prolyl cis-trans isomerase
CEK71_RS18280	COG0587	DNA-directed DNA polymerase activity
CEK71_RS18285	COG2703	oxygen carrier activity
CEK71_RS18300	COG3335	DDE superfamily endonuclease
CEK71_RS18380	COG0330	HflC and HflK could
CEK71_RS18395	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CEK71_RS18430	COG0386	Belongs to the glutathione peroxidase family
CEK71_RS18435	COG1981	membrane
CEK71_RS18445	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CEK71_RS18455	COG0052	Belongs to the universal ribosomal protein uS2 family
CEK71_RS18460	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CEK71_RS18465	COG0528	UMP kinase activity
CEK71_RS18470	COG0233	cytoplasmic translational termination
CEK71_RS18475	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CEK71_RS18480	COG0575	Belongs to the CDS family
CEK71_RS18485	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CEK71_RS18495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEK71_RS18500	COG0586	Pfam SNARE associated Golgi protein
CEK71_RS18515	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CEK71_RS18640	COG0018	arginyl-trna synthetase
CEK71_RS18650	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CEK71_RS18655	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CEK71_RS18660	COG0741	lytic transglycosylase activity
CEK71_RS18665	COG1011	Hydrolase
CEK71_RS18705	COG0318	PFAM AMP-dependent synthetase and ligase
CEK71_RS18710	COG1475	DNA binding
CEK71_RS18725	COG0156	8-amino-7-oxononanoate synthase activity
CEK71_RS18770	COG0646	methionine synthase
CEK71_RS18770	COG1410	methionine synthase
CEK71_RS18880	COG1690	Belongs to the RtcB family
CEK71_RS18930	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CEK71_RS18935	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CEK71_RS18940	COG0716	FMN binding
CEK71_RS18950	COG3086	response to oxidative stress
CEK71_RS18990	COG2201	protein-glutamate methylesterase activity
CEK71_RS18995	COG2198	Histidine kinase
CEK71_RS18995	COG0784	Response regulator, receiver
CEK71_RS18995	COG0643	Histidine kinase
CEK71_RS19005	COG0835	chemotaxis
CEK71_RS19015	COG3706	GGDEF domain
CEK71_RS19015	COG4251	negative regulation of phosphorylation
CEK71_RS19015	COG5001	Diguanylate cyclase
CEK71_RS19015	COG2203	Gaf domain
CEK71_RS19040	COG0662	Cupin 2, conserved barrel domain protein
CEK71_RS19040	COG2207	Transcriptional regulator
CEK71_RS19065	COG2119	membrane
CEK71_RS19085	COG1690	Belongs to the RtcB family
CEK71_RS19090	COG0596	Alpha beta hydrolase
CEK71_RS19095	COG2132	Multicopper oxidase
CEK71_RS19130	COG0742	ribosomal rna small subunit methyltransferase
CEK71_RS19135	COG0612	Peptidase, M16
CEK71_RS19140	COG2814	Major facilitator Superfamily
CEK71_RS19160	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CEK71_RS19165	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CEK71_RS19185	COG0298	carbon dioxide binding
CEK71_RS19195	COG1773	rubredoxin
CEK71_RS19210	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CEK71_RS19250	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CEK71_RS19260	COG1477	protein flavinylation
CEK71_RS19265	COG2205	protein histidine kinase activity
CEK71_RS19270	COG0745	RESPONSE REGULATOR receiver
CEK71_RS19340	COG4804	nuclease activity
CEK71_RS19345	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CEK71_RS19375	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CEK71_RS19410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEK71_RS19430	COG3609	addiction module antidote protein, CC2985 family
CEK71_RS19495	COG1192	Involved in chromosome partitioning
CEK71_RS19550	COG1058	Belongs to the CinA family
CEK71_RS19550	COG1546	Belongs to the CinA family
CEK71_RS19555	COG3023	N-Acetylmuramoyl-L-alanine amidase
CEK71_RS19565	COG0482	sulfurtransferase activity
CEK71_RS19575	COG0420	3'-5' exonuclease activity
CEK71_RS19630	COG1858	cytochrome C peroxidase
CEK71_RS19645	COG1943	Transposase
CEK71_RS19710	COG1122	ATPase activity
CEK71_RS19715	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CEK71_RS19810	COG1253	flavin adenine dinucleotide binding
CEK71_RS19815	COG3961	Belongs to the TPP enzyme family
CEK71_RS19820	COG1914	H( )-stimulated, divalent metal cation uptake system
CEK71_RS19835	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CEK71_RS19840	COG0662	Cupin 2, conserved barrel domain protein
CEK71_RS19855	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CEK71_RS19860	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CEK71_RS19870	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CEK71_RS19875	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CEK71_RS19885	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CEK71_RS19890	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CEK71_RS19895	COG0193	aminoacyl-tRNA hydrolase activity
CEK71_RS19905	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CEK71_RS19910	COG3161	chorismate lyase activity
CEK71_RS19920	COG3660	Nucleoside-diphosphate-sugar epimerase
CEK71_RS19935	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEK71_RS19945	COG0586	Pfam SNARE associated Golgi protein
CEK71_RS19950	COG0326	Molecular chaperone. Has ATPase activity
CEK71_RS19960	COG0612	Peptidase, M16
CEK71_RS20005	COG0631	protein serine/threonine phosphatase activity
CEK71_RS20040	COG1215	transferase activity, transferring glycosyl groups
CEK71_RS20045	COG1216	Glycosyl transferase, family 2
CEK71_RS20115	COG1129	ABC transporter
CEK71_RS20115	COG0842	Transport permease protein
CEK71_RS20120	COG1131	(ABC) transporter
CEK71_RS20150	COG2084	Dehydrogenase
CEK71_RS20155	COG1166	arginine decarboxylase activity
CEK71_RS20160	COG1643	Atp-dependent helicase
CEK71_RS20170	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CEK71_RS20200	COG4251	negative regulation of phosphorylation
CEK71_RS20200	COG5001	Diguanylate cyclase
CEK71_RS20200	COG2203	Gaf domain
CEK71_RS20200	COG3706	GGDEF domain
CEK71_RS20275	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CEK71_RS20285	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEK71_RS20305	COG0235	Class ii aldolase
CEK71_RS20310	COG4456	Virulence-associated protein
CEK71_RS20315	COG1487	ribonuclease activity
CEK71_RS20320	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CEK71_RS20325	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CEK71_RS20360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEK71_RS20370	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CEK71_RS20375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEK71_RS20380	COG1045	serine acetyltransferase
CEK71_RS20395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEK71_RS20400	COG2132	Multicopper oxidase
CEK71_RS20400	COG2132	Multicopper oxidase
CEK71_RS20455	COG4636	protein conserved in cyanobacteria
CEK71_RS20465	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CEK71_RS20470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEK71_RS20475	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CEK71_RS20490	COG0142	geranyltranstransferase activity
CEK71_RS20595	COG1733	regulation of RNA biosynthetic process
CEK71_RS20600	COG0702	epimerase
CEK71_RS20625	COG2132	Multicopper oxidase
CEK71_RS20675	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
CEK71_RS20685	COG0501	Belongs to the peptidase M48B family
CEK71_RS20820	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CEK71_RS20825	COG1607	acyl-coa hydrolase
CEK71_RS20835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEK71_RS20855	COG0473	3-isopropylmalate dehydrogenase activity
CEK71_RS20860	COG2353	YceI-like domain
CEK71_RS20865	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CEK71_RS20870	COG0583	DNA-binding transcription factor activity
CEK71_RS20890	COG3311	Transcriptional regulator
CEK71_RS20900	COG4974	Belongs to the 'phage' integrase family
CEK71_RS20970	COG0463	Glycosyl transferase, family 2
CEK71_RS20970	COG0457	Tetratricopeptide repeat
CEK71_RS20975	COG4128	Pfam Zonular occludens toxin
CEK71_RS21040	COG3344	reverse transcriptase
CEK71_RS21050	COG3550	peptidyl-serine autophosphorylation
CEK71_RS21080	COG0154	amidase activity
CEK71_RS21085	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CEK71_RS21090	COG1077	Cell shape determining protein MreB Mrl
CEK71_RS21150	COG2003	Belongs to the UPF0758 family
CEK71_RS21185	COG1192	Involved in chromosome partitioning
CEK71_RS21190	COG0357	Ribosomal RNA small subunit methyltransferase G
CEK71_RS21195	COG0445	tRNA wobble uridine modification
CEK71_RS21220	COG0513	Belongs to the DEAD box helicase family
CEK71_RS21255	COG0187	DNA topoisomerase II activity
CEK71_RS21275	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CEK71_RS21310	COG1228	amidohydrolase
CEK71_RS21380	COG0582	viral genome integration into host DNA
CEK71_RS21385	COG2801	Transposase and inactivated derivatives
CEK71_RS21445	COG2814	Major facilitator Superfamily
CEK71_RS21450	COG0768	penicillin binding
CEK71_RS21460	COG1792	Involved in formation and maintenance of cell shape
CEK71_RS21470	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CEK71_RS21500	COG0438	transferase activity, transferring glycosyl groups
CEK71_RS21585	COG0589	response to stress
CEK71_RS21650	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CEK71_RS21655	COG1040	competence protein
CEK71_RS21665	COG0343	queuine tRNA-ribosyltransferase activity
CEK71_RS21750	COG3657	addiction module killer protein
CEK71_RS21770	COG1091	dTDP-4-dehydrorhamnose reductase activity
CEK71_RS21815	COG1192	Involved in chromosome partitioning
CEK71_RS21915	COG0210	DNA helicase
CEK71_RS21955	COG1028	Short-chain dehydrogenase reductase Sdr
CEK71_RS21965	COG2890	protein-(glutamine-N5) methyltransferase activity
CEK71_RS22040	COG0582	viral genome integration into host DNA
CEK71_RS22085	COG4372	Transposase
CEK71_RS22140	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CEK71_RS22185	COG4372	Transposase
CEK71_RS22295	COG3415	Transposase
CEK71_RS22295	COG2801	Transposase and inactivated derivatives