locus-tag	class	description
FIV50_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FIV50_RS00010	COG0592	DNA-directed DNA polymerase activity
FIV50_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FIV50_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
FIV50_RS00025	COG0187	DNA topoisomerase II activity
FIV50_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FIV50_RS00040	COG3850	Histidine kinase
FIV50_RS00045	COG2197	response regulator
FIV50_RS00120	COG3764	Sortase (surface protein transpeptidase)
FIV50_RS00130	COG0515	serine threonine protein kinase
FIV50_RS00130	COG2815	serine threonine protein kinase
FIV50_RS00135	COG0515	serine threonine protein kinase
FIV50_RS00140	COG0768	penicillin binding
FIV50_RS00155	COG1716	ATPase activity
FIV50_RS00160	COG1716	ATPase activity
FIV50_RS00170	COG2197	response regulator
FIV50_RS00175	COG3850	Histidine kinase
FIV50_RS00220	COG0667	Aldo Keto reductase
FIV50_RS00255	COG4948	Mandelate Racemase Muconate Lactonizing
FIV50_RS00260	COG0477	Major facilitator Superfamily
FIV50_RS00265	COG1063	alcohol dehydrogenase
FIV50_RS00270	COG0246	Mannitol dehydrogenase
FIV50_RS00295	COG2197	response regulator
FIV50_RS00300	COG4585	Histidine kinase
FIV50_RS00310	COG1136	(ABC) transporter
FIV50_RS00325	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FIV50_RS00335	COG1846	Transcriptional regulator
FIV50_RS00340	COG2814	Major facilitator Superfamily
FIV50_RS00345	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FIV50_RS00350	COG1278	Cold shock
FIV50_RS00355	COG0546	phosphoglycolate phosphatase activity
FIV50_RS00360	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
FIV50_RS00370	COG0738	Major facilitator superfamily
FIV50_RS00375	COG1609	Transcriptional regulator
FIV50_RS00385	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FIV50_RS00385	COG2111	Na H antiporter
FIV50_RS00395	COG0651	ATP synthesis coupled electron transport
FIV50_RS00405	COG2212	antiporter activity
FIV50_RS00410	COG1320	monovalent cation:proton antiporter activity
FIV50_RS00430	COG2366	antibiotic biosynthetic process
FIV50_RS00460	COG0477	Major facilitator Superfamily
FIV50_RS00525	COG0714	Associated with various cellular activities
FIV50_RS00535	COG0697	spore germination
FIV50_RS00540	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FIV50_RS00570	COG1174	glycine betaine transport
FIV50_RS00590	COG1605	Chorismate mutase
FIV50_RS00590	COG0287	Prephenate dehydrogenase
FIV50_RS00600	COG0395	ABC-type sugar transport system, permease component
FIV50_RS00615	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FIV50_RS00635	COG1349	DNA-binding transcription factor activity
FIV50_RS00675	COG1028	Short-chain dehydrogenase reductase Sdr
FIV50_RS00700	COG1131	(ABC) transporter
FIV50_RS00715	COG1131	(ABC) transporter
FIV50_RS00720	COG1309	transcriptional regulator
FIV50_RS00725	COG2197	response regulator
FIV50_RS00770	COG4176	ABC-type proline glycine betaine transport system permease component
FIV50_RS00875	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FIV50_RS00880	COG3639	organic phosphonate transmembrane transporter activity
FIV50_RS00895	COG2409	Drug exporters of the RND superfamily
FIV50_RS00910	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FIV50_RS00920	COG2764	glyoxalase bleomycin resistance protein dioxygenase
FIV50_RS00940	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FIV50_RS00945	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
FIV50_RS00960	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FIV50_RS01000	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FIV50_RS01100	COG1401	restriction endodeoxyribonuclease activity
FIV50_RS01105	COG1160	GTP binding
FIV50_RS01130	COG1609	Transcriptional regulator
FIV50_RS01135	COG1178	ABC-type Fe3 transport system permease component
FIV50_RS01140	COG3842	ATPase activity
FIV50_RS01145	COG1840	ABC-type Fe3 transport system, periplasmic component
FIV50_RS01155	COG0659	secondary active sulfate transmembrane transporter activity
FIV50_RS01165	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FIV50_RS01170	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FIV50_RS01175	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FIV50_RS01185	COG3655	Transcriptional regulator
FIV50_RS01200	COG0640	Transcriptional regulator
FIV50_RS01215	COG0024	Methionine aminopeptidase
FIV50_RS01220	COG1216	Glycosyl transferase, family 2
FIV50_RS01230	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FIV50_RS01235	COG3177	Filamentation induced by cAMP protein fic
FIV50_RS01240	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIV50_RS01260	COG0477	Major facilitator Superfamily
FIV50_RS01290	COG0738	Major facilitator superfamily
FIV50_RS01300	COG1609	Transcriptional regulator
FIV50_RS01310	COG1175	transmembrane transport
FIV50_RS01320	COG1621	beta-fructofuranosidase activity
FIV50_RS01340	COG1064	alcohol dehydrogenase
FIV50_RS01360	COG0328	RNA-DNA hybrid ribonuclease activity
FIV50_RS01395	COG1733	regulation of RNA biosynthetic process
FIV50_RS01400	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FIV50_RS01405	COG2205	protein histidine kinase activity
FIV50_RS01410	COG0745	RESPONSE REGULATOR receiver
FIV50_RS01420	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FIV50_RS01425	COG1181	Belongs to the D-alanine--D-alanine ligase family
FIV50_RS01445	COG0813	purine-nucleoside phosphorylase activity
FIV50_RS01470	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FIV50_RS01470	COG1672	PFAM Archaeal ATPase
FIV50_RS01475	COG1278	Cold shock
FIV50_RS01485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIV50_RS01490	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIV50_RS01495	COG1120	ATPase activity
FIV50_RS01530	COG1175	transmembrane transport
FIV50_RS01535	COG3833	ABC-type maltose transport systems, permease component
FIV50_RS01540	COG3867	Arabinogalactan endo-beta-1,4-galactanase
FIV50_RS01545	COG2267	carboxylic ester hydrolase activity
FIV50_RS01575	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FIV50_RS01585	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FIV50_RS01595	COG4941	Belongs to the sigma-70 factor family
FIV50_RS01615	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FIV50_RS01640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIV50_RS01645	COG0531	amino acid
FIV50_RS01655	COG2357	RelA SpoT domain protein
FIV50_RS01670	COG0315	cyclic pyranopterin monophosphate synthase activity
FIV50_RS01670	COG0521	Mo-molybdopterin cofactor biosynthetic process
FIV50_RS01675	COG0314	molybdopterin synthase activity
FIV50_RS01685	COG0315	cyclic pyranopterin monophosphate synthase activity
FIV50_RS01715	COG3842	ATPase activity
FIV50_RS01720	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FIV50_RS01740	COG0444	Belongs to the ABC transporter superfamily
FIV50_RS01750	COG0601	transmembrane transport
FIV50_RS01785	COG0569	domain protein
FIV50_RS01790	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIV50_RS01795	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FIV50_RS01805	COG0640	Transcriptional regulator
FIV50_RS01810	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FIV50_RS01815	COG1115	amino acid carrier protein
FIV50_RS01820	COG1609	Transcriptional regulator
FIV50_RS01825	COG0366	Alpha amylase catalytic
FIV50_RS01840	COG0047	phosphoribosylformylglycinamidine synthase activity
FIV50_RS01850	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FIV50_RS01860	COG1175	transmembrane transport
FIV50_RS01865	COG0395	ABC-type sugar transport system, permease component
FIV50_RS01870	COG2723	6-phospho-beta-galactosidase activity
FIV50_RS01885	COG1309	transcriptional regulator
FIV50_RS01895	COG1914	H( )-stimulated, divalent metal cation uptake system
FIV50_RS01900	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FIV50_RS01905	COG4336	lyase activity
FIV50_RS01910	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FIV50_RS01915	COG4770	biotin carboxylase activity
FIV50_RS01920	COG2233	PERMEase
FIV50_RS01925	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FIV50_RS01965	COG0151	Belongs to the GarS family
FIV50_RS01990	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FIV50_RS02000	COG2807	transmembrane transport
FIV50_RS02030	COG0058	SHG alpha-glucan phosphorylase activity
FIV50_RS02035	COG0789	Transcriptional regulator
FIV50_RS02045	COG0778	Nitroreductase
FIV50_RS02060	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FIV50_RS02065	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FIV50_RS02075	COG1175	transmembrane transport
FIV50_RS02085	COG1609	Transcriptional regulator
FIV50_RS02095	COG3226	Transcriptional regulator
FIV50_RS02100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIV50_RS02105	COG2017	converts alpha-aldose to the beta-anomer
FIV50_RS02110	COG0513	Belongs to the DEAD box helicase family
FIV50_RS02115	COG4681	YaeQ
FIV50_RS02135	COG1960	acyl-CoA dehydrogenase activity
FIV50_RS02140	COG3609	addiction module antidote protein, CC2985 family
FIV50_RS02145	COG2337	Toxic component of a toxin-antitoxin (TA) module
FIV50_RS02160	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FIV50_RS02165	COG1122	ATPase activity
FIV50_RS02175	COG1404	Belongs to the peptidase S8 family
FIV50_RS02195	COG0514	ATP-dependent DNA helicase (RecQ)
FIV50_RS02265	COG0519	Catalyzes the synthesis of GMP from XMP
FIV50_RS02270	COG2815	serine threonine protein kinase
FIV50_RS02270	COG0515	serine threonine protein kinase
FIV50_RS02280	COG0714	Associated with various cellular activities
FIV50_RS02310	COG1404	Belongs to the peptidase S8 family
FIV50_RS02360	COG1674	ftsk spoiiie
FIV50_RS02375	COG0039	L-malate dehydrogenase activity
FIV50_RS02415	COG0463	Glycosyl transferase, family 2
FIV50_RS02430	COG0438	transferase activity, transferring glycosyl groups
FIV50_RS02465	COG2244	polysaccharide biosynthetic process
FIV50_RS02490	COG0489	protein tyrosine kinase activity
FIV50_RS02500	COG0297	glycogen (starch) synthase activity
FIV50_RS02510	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FIV50_RS02525	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIV50_RS02530	COG0805	protein transport
FIV50_RS02555	COG2197	response regulator
FIV50_RS02570	COG1131	(ABC) transporter
FIV50_RS02625	COG2197	response regulator
FIV50_RS02690	COG1573	uracil-dna glycosylase
FIV50_RS02765	COG1937	Protein conserved in bacteria
FIV50_RS02775	COG2217	Heavy metal translocating P-type atpase
FIV50_RS02805	COG4974	Belongs to the 'phage' integrase family
FIV50_RS02830	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FIV50_RS02840	COG0037	tRNA processing
FIV50_RS02855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIV50_RS02860	COG0302	gtp cyclohydrolase
FIV50_RS02865	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FIV50_RS02875	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FIV50_RS02905	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FIV50_RS02925	COG1597	lipid kinase activity
FIV50_RS02930	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FIV50_RS02935	COG0561	phosphatase activity
FIV50_RS02945	COG1316	TRANSCRIPTIONal
FIV50_RS02955	COG1472	Belongs to the glycosyl hydrolase 3 family
FIV50_RS02965	COG4948	Mandelate Racemase Muconate Lactonizing
FIV50_RS02970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIV50_RS02980	COG0673	inositol 2-dehydrogenase activity
FIV50_RS02990	COG1609	Transcriptional regulator
FIV50_RS03005	COG0395	ABC-type sugar transport system, permease component
FIV50_RS03020	COG1653	transport
FIV50_RS03030	COG4209	transmembrane transport
FIV50_RS03035	COG1609	Transcriptional regulator
FIV50_RS03050	COG1609	Transcriptional regulator
FIV50_RS03055	COG1129	ABC transporter
FIV50_RS03065	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV50_RS03070	COG1879	ABC-type sugar transport system periplasmic component
FIV50_RS03075	COG1070	Carbohydrate kinase
FIV50_RS03080	COG3347	Dehydrogenase
FIV50_RS03080	COG1028	Short-chain dehydrogenase reductase Sdr
FIV50_RS03100	COG3401	FG-GAP repeat protein
FIV50_RS03110	COG1132	(ABC) transporter
FIV50_RS03115	COG0673	inositol 2-dehydrogenase activity
FIV50_RS03130	COG1175	transmembrane transport
FIV50_RS03135	COG0395	ABC-type sugar transport system, permease component
FIV50_RS03145	COG1609	Transcriptional regulator
FIV50_RS03160	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIV50_RS03170	COG1648	precorrin-2 dehydrogenase activity
FIV50_RS03170	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FIV50_RS03185	COG2116	formate transmembrane transporter activity
FIV50_RS03195	COG0667	Aldo Keto reductase
FIV50_RS03200	COG1802	Transcriptional regulator
FIV50_RS03220	COG1609	Transcriptional regulator
FIV50_RS03225	COG0673	inositol 2-dehydrogenase activity
FIV50_RS03240	COG1070	Carbohydrate kinase
FIV50_RS03245	COG2115	Belongs to the xylose isomerase family
FIV50_RS03255	COG2207	Transcriptional regulator
FIV50_RS03255	COG3708	Transcriptional regulator
FIV50_RS03295	COG2508	Transcriptional regulator
FIV50_RS03310	COG0822	iron-sulfur transferase activity
FIV50_RS03360	COG0583	DNA-binding transcription factor activity
FIV50_RS03365	COG1053	succinate dehydrogenase
FIV50_RS03375	COG1760	l-serine dehydratase
FIV50_RS03385	COG1643	Atp-dependent helicase
FIV50_RS03405	COG1131	(ABC) transporter
FIV50_RS03425	COG2197	response regulator
FIV50_RS03445	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FIV50_RS03455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIV50_RS03460	COG1121	(ABC) transporter
FIV50_RS03475	COG2197	response regulator
FIV50_RS03500	COG1733	regulation of RNA biosynthetic process
FIV50_RS03505	COG0604	alcohol dehydrogenase
FIV50_RS03505	COG3321	synthase
FIV50_RS03505	COG1028	Short-chain dehydrogenase reductase Sdr
FIV50_RS03515	COG4585	Histidine kinase
FIV50_RS03520	COG2197	response regulator
FIV50_RS03545	COG1175	transmembrane transport
FIV50_RS03570	COG2197	response regulator
FIV50_RS03610	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FIV50_RS03635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIV50_RS03665	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FIV50_RS03695	COG0745	RESPONSE REGULATOR receiver
FIV50_RS03715	COG0419	ATPase involved in DNA repair
FIV50_RS03755	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FIV50_RS03760	COG0590	tRNA wobble adenosine to inosine editing
FIV50_RS03760	COG0037	tRNA processing
FIV50_RS03770	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FIV50_RS03780	COG0569	domain protein
FIV50_RS03785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIV50_RS03790	COG0640	Transcriptional regulator
FIV50_RS03820	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIV50_RS03860	COG0765	amino acid transport
FIV50_RS03865	COG1126	abc transporter atp-binding protein
FIV50_RS03870	COG3842	ATPase activity
FIV50_RS03895	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FIV50_RS03905	COG0406	alpha-ribazole phosphatase activity
FIV50_RS03915	COG3634	alkyl hydroperoxide reductase activity
FIV50_RS03930	COG0785	Cytochrome C biogenesis protein
FIV50_RS03940	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIV50_RS03955	COG2409	Drug exporters of the RND superfamily
FIV50_RS03960	COG1309	transcriptional regulator
FIV50_RS03965	COG4948	Mandelate Racemase Muconate Lactonizing
FIV50_RS03985	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FIV50_RS03995	COG2226	methyltransferase
FIV50_RS04000	COG4585	Histidine kinase
FIV50_RS04005	COG2197	response regulator
FIV50_RS04010	COG1136	(ABC) transporter
FIV50_RS04050	COG1175	transmembrane transport
FIV50_RS04055	COG0395	ABC-type sugar transport system, permease component
FIV50_RS04060	COG1472	Belongs to the glycosyl hydrolase 3 family
FIV50_RS04065	COG1737	Transcriptional regulator
FIV50_RS04075	COG0747	negative chemotaxis
FIV50_RS04080	COG0601	transmembrane transport
FIV50_RS04085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIV50_RS04095	COG0085	RNA polymerase activity
FIV50_RS04100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FIV50_RS04120	COG2409	Drug exporters of the RND superfamily
FIV50_RS04145	COG3265	gluconokinase activity
FIV50_RS04155	COG1420	regulation of RNA biosynthetic process
FIV50_RS04175	COG0483	inositol monophosphate 1-phosphatase activity
FIV50_RS04180	COG0739	heme binding
FIV50_RS04215	COG1595	DNA-templated transcription, initiation
FIV50_RS04230	COG0702	epimerase
FIV50_RS04235	COG1733	regulation of RNA biosynthetic process
FIV50_RS04245	COG0101	tRNA pseudouridine synthase activity
FIV50_RS04265	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FIV50_RS04270	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FIV50_RS04275	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIV50_RS04280	COG0248	Ppx GppA phosphatase
FIV50_RS04285	COG1072	(Pantothenic acid kinase))
FIV50_RS04290	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FIV50_RS04300	COG0736	holo-[acyl-carrier-protein] synthase activity
FIV50_RS04305	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FIV50_RS04310	COG0802	atpase or kinase
FIV50_RS04325	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FIV50_RS04350	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FIV50_RS04400	COG0745	RESPONSE REGULATOR receiver
FIV50_RS04410	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FIV50_RS04420	COG0745	RESPONSE REGULATOR receiver
FIV50_RS04425	COG2205	protein histidine kinase activity
FIV50_RS04430	COG0488	(ABC) transporter
FIV50_RS04435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIV50_RS04440	COG0516	GMP reductase activity
FIV50_RS04450	COG4085	toxin activity
FIV50_RS04450	COG0737	Belongs to the 5'-nucleotidase family
FIV50_RS04450	COG1525	nuclease
FIV50_RS04455	COG1349	DNA-binding transcription factor activity
FIV50_RS04460	COG1105	Belongs to the carbohydrate kinase PfkB family
FIV50_RS04465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIV50_RS04465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIV50_RS04465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIV50_RS04470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIV50_RS04485	COG1175	transmembrane transport
FIV50_RS04490	COG0395	ABC-type sugar transport system, permease component
FIV50_RS04515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FIV50_RS04515	COG0519	Catalyzes the synthesis of GMP from XMP
FIV50_RS04520	COG0039	L-malate dehydrogenase activity
FIV50_RS04530	COG4941	Belongs to the sigma-70 factor family
FIV50_RS04535	COG2261	transglycosylase associated protein
FIV50_RS04545	COG0584	glycerophosphoryl diester phosphodiesterase
FIV50_RS04555	COG3304	Inner membrane component domain
FIV50_RS04605	COG1793	dna ligase
FIV50_RS04660	COG1309	transcriptional regulator
FIV50_RS04675	COG1404	Belongs to the peptidase S8 family
FIV50_RS04685	COG0045	succinate-CoA ligase (ADP-forming) activity
FIV50_RS04700	COG2252	PERMEase
FIV50_RS04715	COG0138	bifunctional purine biosynthesis protein purh
FIV50_RS04725	COG2169	Transcriptional regulator
FIV50_RS04725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FIV50_RS04730	COG1132	(ABC) transporter
FIV50_RS04735	COG1132	(ABC) transporter
FIV50_RS04750	COG1501	Belongs to the glycosyl hydrolase 31 family
FIV50_RS04755	COG0395	ABC-type sugar transport system, permease component
FIV50_RS04760	COG1175	transmembrane transport
FIV50_RS04770	COG1609	Transcriptional regulator
FIV50_RS04780	COG2838	Isocitrate dehydrogenase
FIV50_RS04820	COG1051	belongs to the nudix hydrolase family
FIV50_RS04825	COG0277	FAD linked oxidase domain protein
FIV50_RS04840	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FIV50_RS04850	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FIV50_RS04855	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FIV50_RS04870	COG1053	succinate dehydrogenase
FIV50_RS04875	COG4565	transcriptional regulatory protein
FIV50_RS04880	COG3290	protein histidine kinase activity
FIV50_RS04905	COG3971	2-oxopent-4-enoate hydratase activity
FIV50_RS04915	COG1012	belongs to the aldehyde dehydrogenase family
FIV50_RS04920	COG1802	Transcriptional regulator
FIV50_RS04930	COG0477	Major facilitator Superfamily
FIV50_RS04935	COG1414	Transcriptional regulator
FIV50_RS04955	COG0384	phenazine biosynthesis protein PhzF
FIV50_RS04975	COG1305	Transglutaminase-like
FIV50_RS04980	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FIV50_RS04985	COG1793	dna ligase
FIV50_RS04990	COG1024	Enoyl-CoA hydratase
FIV50_RS04995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIV50_RS05000	COG2151	metal-sulfur cluster biosynthetic enzyme
FIV50_RS05005	COG3396	Phenylacetate-CoA oxygenase
FIV50_RS05010	COG3460	Phenylacetate-CoA oxygenase
FIV50_RS05015	COG3396	Phenylacetate-CoA oxygenase
FIV50_RS05025	COG0514	ATP-dependent DNA helicase (RecQ)
FIV50_RS05045	COG2050	protein possibly involved in aromatic compounds catabolism
FIV50_RS05050	COG2030	dehydratase
FIV50_RS05050	COG1012	belongs to the aldehyde dehydrogenase family
FIV50_RS05055	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIV50_RS05060	COG1024	Enoyl-CoA hydratase
FIV50_RS05065	COG0183	Belongs to the thiolase family
FIV50_RS05070	COG1309	transcriptional regulator
FIV50_RS05080	COG2376	Dihydroxyacetone kinase
FIV50_RS05085	COG1461	Dihydroxyacetone kinase
FIV50_RS05090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FIV50_RS05105	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIV50_RS05110	COG0022	dehydrogenase e1 component
FIV50_RS05125	COG1012	belongs to the aldehyde dehydrogenase family
FIV50_RS05150	COG4221	oxidoreductase activity
FIV50_RS05165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIV50_RS05210	COG1737	Transcriptional regulator
FIV50_RS05220	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FIV50_RS05230	COG3226	Transcriptional regulator
FIV50_RS05265	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FIV50_RS05270	COG1132	(ABC) transporter
FIV50_RS05280	COG1619	proteins homologs of microcin C7 resistance protein MccF
FIV50_RS05285	COG0477	Major facilitator Superfamily
FIV50_RS05315	COG0395	ABC-type sugar transport system, permease component
FIV50_RS05325	COG1609	Transcriptional regulator
FIV50_RS05330	COG0477	Major facilitator Superfamily
FIV50_RS05335	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FIV50_RS05385	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FIV50_RS05390	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIV50_RS05390	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIV50_RS05405	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FIV50_RS05420	COG1028	Short-chain dehydrogenase reductase Sdr
FIV50_RS05430	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FIV50_RS05435	COG0531	amino acid
FIV50_RS05440	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FIV50_RS05445	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FIV50_RS05450	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FIV50_RS05460	COG0124	histidyl-tRNA synthetase
FIV50_RS05465	COG2755	lipolytic protein G-D-S-L family
FIV50_RS05505	COG4122	O-methyltransferase activity
FIV50_RS05510	COG0148	phosphopyruvate hydratase activity
FIV50_RS05525	COG1404	Belongs to the peptidase S8 family
FIV50_RS05540	COG0586	Pfam SNARE associated Golgi protein
FIV50_RS05560	COG1704	LemA family
FIV50_RS05570	COG3214	Protein conserved in bacteria
FIV50_RS05580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FIV50_RS05585	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIV50_RS05600	COG1272	protein, Hemolysin III
FIV50_RS05605	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FIV50_RS05610	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FIV50_RS05615	COG1966	Carbon starvation protein
FIV50_RS05630	COG0114	fumarate hydratase activity
FIV50_RS05645	COG1722	exodeoxyribonuclease VII activity
FIV50_RS05650	COG1570	exodeoxyribonuclease VII activity
FIV50_RS05655	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FIV50_RS05670	COG0191	fructose-bisphosphate aldolase activity
FIV50_RS05685	COG1322	Protein conserved in bacteria
FIV50_RS05690	COG2176	DNA-directed DNA polymerase activity
FIV50_RS05700	COG0012	GTP binding
FIV50_RS05735	COG0488	(ABC) transporter
FIV50_RS05755	COG0783	Belongs to the Dps family
FIV50_RS05775	COG2814	Major facilitator Superfamily
FIV50_RS05780	COG1132	(ABC) transporter
FIV50_RS05785	COG1028	Short-chain dehydrogenase reductase Sdr
FIV50_RS05790	COG1216	Glycosyl transferase, family 2
FIV50_RS05805	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FIV50_RS05810	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FIV50_RS05820	COG0747	negative chemotaxis
FIV50_RS05825	COG0601	transmembrane transport
FIV50_RS05835	COG0444	Belongs to the ABC transporter superfamily
FIV50_RS05840	COG4608	Belongs to the ABC transporter superfamily
FIV50_RS05845	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIV50_RS05850	COG0509	glycine decarboxylation via glycine cleavage system
FIV50_RS05855	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FIV50_RS05855	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FIV50_RS05860	COG4166	transmembrane transport
FIV50_RS05870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIV50_RS05890	COG1217	gtp-binding protein TYPA
FIV50_RS05900	COG2066	Belongs to the glutaminase family
FIV50_RS05905	COG0477	Major facilitator Superfamily
FIV50_RS05955	COG2171	N-acyltransferase activity
FIV50_RS05960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIV50_RS05980	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIV50_RS06000	COG2239	Acts as a magnesium transporter
FIV50_RS06020	COG0346	lactoylglutathione lyase activity
FIV50_RS06030	COG0006	proline dipeptidase activity
FIV50_RS06040	COG2176	DNA-directed DNA polymerase activity
FIV50_RS06045	COG0513	Belongs to the DEAD box helicase family
FIV50_RS06070	COG0210	DNA helicase
FIV50_RS06075	COG0210	DNA helicase
FIV50_RS06100	COG3480	Lon protease (S16) C-terminal proteolytic domain
FIV50_RS06105	COG1615	UPF0182 protein
FIV50_RS06130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIV50_RS06140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIV50_RS06145	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FIV50_RS06150	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FIV50_RS06155	COG1215	transferase activity, transferring glycosyl groups
FIV50_RS06165	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FIV50_RS06165	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FIV50_RS06180	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FIV50_RS06215	COG0438	transferase activity, transferring glycosyl groups
FIV50_RS06235	COG1215	transferase activity, transferring glycosyl groups
FIV50_RS06270	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FIV50_RS06275	COG1088	dTDP-glucose 4,6-dehydratase activity
FIV50_RS06285	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FIV50_RS06285	COG2755	lipolytic protein G-D-S-L family
FIV50_RS06290	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FIV50_RS06290	COG2755	lipolytic protein G-D-S-L family
FIV50_RS06310	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
FIV50_RS06315	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FIV50_RS06320	COG1086	Polysaccharide biosynthesis protein
FIV50_RS06330	COG2089	acid synthase
FIV50_RS06365	COG1482	cell wall glycoprotein biosynthetic process
FIV50_RS06400	COG1136	(ABC) transporter
FIV50_RS06400	COG0577	efflux transmembrane transporter activity
FIV50_RS06405	COG0577	efflux transmembrane transporter activity
FIV50_RS06405	COG1136	(ABC) transporter
FIV50_RS06425	COG0714	Associated with various cellular activities
FIV50_RS06445	COG0745	RESPONSE REGULATOR receiver
FIV50_RS06450	COG5002	protein histidine kinase activity
FIV50_RS06450	COG5000	phosphorelay sensor kinase activity
FIV50_RS06455	COG5401	PFAM Sporulation and spore germination
FIV50_RS06480	COG0653	protein targeting
FIV50_RS06540	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FIV50_RS06545	COG1595	DNA-templated transcription, initiation
FIV50_RS06555	COG4552	Acetyltransferase involved in intracellular survival and related
FIV50_RS06560	COG0567	Dehydrogenase, E1 component
FIV50_RS06560	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIV50_RS06580	COG1902	pentaerythritol trinitrate reductase activity
FIV50_RS06600	COG2814	Major facilitator Superfamily
FIV50_RS06610	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FIV50_RS06670	COG0747	negative chemotaxis
FIV50_RS06675	COG0596	Alpha beta hydrolase
FIV50_RS06675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FIV50_RS06705	COG1842	Phage shock protein A
FIV50_RS06720	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FIV50_RS06740	COG0604	alcohol dehydrogenase
FIV50_RS06740	COG3321	synthase
FIV50_RS06740	COG1028	Short-chain dehydrogenase reductase Sdr
FIV50_RS06745	COG1764	response to oxidative stress
FIV50_RS06750	COG1846	Transcriptional regulator
FIV50_RS06765	COG0628	permease
FIV50_RS06780	COG0018	arginyl-trna synthetase
FIV50_RS06795	COG0019	diaminopimelate decarboxylase activity
FIV50_RS06800	COG0460	homoserine dehydrogenase
FIV50_RS06805	COG0083	homoserine kinase activity
FIV50_RS06815	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FIV50_RS06825	COG1045	serine acetyltransferase
FIV50_RS06835	COG2890	protein-(glutamine-N5) methyltransferase activity
FIV50_RS06845	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FIV50_RS06855	COG0356	it plays a direct role in the translocation of protons across the membrane
FIV50_RS06860	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FIV50_RS06865	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FIV50_RS06870	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FIV50_RS06875	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FIV50_RS06880	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FIV50_RS06885	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FIV50_RS06890	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FIV50_RS06895	COG3022	response to hydroperoxide
FIV50_RS06905	COG0631	protein serine/threonine phosphatase activity
FIV50_RS06935	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FIV50_RS06940	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FIV50_RS06955	COG0750	zinc metalloprotease
FIV50_RS06965	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FIV50_RS06990	COG0557	exoribonuclease II activity
FIV50_RS07005	COG0442	prolyl-tRNA aminoacylation
FIV50_RS07015	COG1611	Belongs to the LOG family
FIV50_RS07020	COG1231	oxidoreductase activity
FIV50_RS07035	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FIV50_RS07040	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FIV50_RS07045	COG2197	response regulator
FIV50_RS07050	COG1194	a g-specific adenine glycosylase
FIV50_RS07055	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FIV50_RS07070	COG0196	riboflavin kinase activity
FIV50_RS07075	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FIV50_RS07115	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIV50_RS07130	COG0545	Peptidyl-prolyl cis-trans isomerase
FIV50_RS07140	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FIV50_RS07165	COG2822	iron ion transport
FIV50_RS07170	COG2837	iron assimilation
FIV50_RS07180	COG3594	Acyltransferase
FIV50_RS07210	COG1301	dicarboxylic acid transport
FIV50_RS07220	COG0438	transferase activity, transferring glycosyl groups
FIV50_RS07225	COG1185	polyribonucleotide nucleotidyltransferase activity
FIV50_RS07230	COG0667	Aldo Keto reductase
FIV50_RS07250	COG1764	response to oxidative stress
FIV50_RS07265	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FIV50_RS07285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIV50_RS07290	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FIV50_RS07300	COG1674	ftsk spoiiie
FIV50_RS07310	COG1058	Belongs to the CinA family
FIV50_RS07310	COG1546	Belongs to the CinA family
FIV50_RS07315	COG1396	sequence-specific DNA binding
FIV50_RS07325	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FIV50_RS07330	COG2137	regulation of response to DNA damage stimulus
FIV50_RS07335	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FIV50_RS07340	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FIV50_RS07345	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FIV50_RS07350	COG0456	acetyltransferase
FIV50_RS07355	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FIV50_RS07360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIV50_RS07370	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FIV50_RS07405	COG0483	inositol monophosphate 1-phosphatase activity
FIV50_RS07425	COG2814	Major facilitator Superfamily
FIV50_RS07450	COG0183	Belongs to the thiolase family
FIV50_RS07465	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FIV50_RS07475	COG0129	dihydroxy-acid dehydratase activity
FIV50_RS07480	COG0028	Belongs to the TPP enzyme family
FIV50_RS07490	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FIV50_RS07515	COG1309	transcriptional regulator
FIV50_RS07520	COG0477	Major facilitator Superfamily
FIV50_RS07525	COG0473	3-isopropylmalate dehydrogenase activity
FIV50_RS07530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FIV50_RS07535	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIV50_RS07540	COG2814	Major facilitator Superfamily
FIV50_RS07555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIV50_RS07575	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIV50_RS07640	COG2873	o-acetylhomoserine
FIV50_RS07645	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FIV50_RS07650	COG0066	3-isopropylmalate dehydratase activity
FIV50_RS07655	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FIV50_RS07660	COG0204	Acyl-transferase
FIV50_RS07660	COG0318	PFAM AMP-dependent synthetase and ligase
FIV50_RS07665	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FIV50_RS07670	COG1181	Belongs to the D-alanine--D-alanine ligase family
FIV50_RS07685	COG0742	ribosomal rna small subunit methyltransferase
FIV50_RS07690	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FIV50_RS07695	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FIV50_RS07705	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FIV50_RS07710	COG0571	ribonuclease III activity
FIV50_RS07715	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FIV50_RS07745	COG1196	nuclear chromosome segregation
FIV50_RS07750	COG0552	protein localization to endoplasmic reticulum
FIV50_RS07760	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FIV50_RS07765	COG0321	lipoyl(octanoyl) transferase activity
FIV50_RS07770	COG1309	transcriptional regulator
FIV50_RS07780	COG0697	spore germination
FIV50_RS07785	COG0583	DNA-binding transcription factor activity
FIV50_RS07790	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FIV50_RS07795	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FIV50_RS07800	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FIV50_RS07810	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FIV50_RS07815	COG0228	four-way junction DNA binding
FIV50_RS07820	COG1837	Belongs to the UPF0109 family
FIV50_RS07825	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FIV50_RS07830	COG0336	Belongs to the RNA methyltransferase TrmD family
FIV50_RS07840	COG2226	methyltransferase
FIV50_RS07855	COG0335	large ribosomal subunit rRNA binding
FIV50_RS07865	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FIV50_RS07885	COG0792	nuclease activity
FIV50_RS07910	COG0052	Belongs to the universal ribosomal protein uS2 family
FIV50_RS07915	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FIV50_RS07920	COG0528	UMP kinase activity
FIV50_RS07925	COG0233	cytoplasmic translational termination
FIV50_RS07955	COG0628	permease
FIV50_RS07965	COG3118	belongs to the thioredoxin family
FIV50_RS07970	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FIV50_RS07975	COG0366	Alpha amylase catalytic
FIV50_RS07990	COG0482	sulfurtransferase activity
FIV50_RS07995	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FIV50_RS08015	COG0318	PFAM AMP-dependent synthetase and ligase
FIV50_RS08020	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FIV50_RS08025	COG0154	amidase activity
FIV50_RS08030	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FIV50_RS08035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FIV50_RS08055	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FIV50_RS08065	COG1280	lysine exporter protein (LysE YggA)
FIV50_RS08075	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FIV50_RS08110	COG1946	Acyl-CoA thioesterase
FIV50_RS08130	COG0668	transmembrane transport
FIV50_RS08140	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FIV50_RS08155	COG2808	Putative FMN-binding domain
FIV50_RS08165	COG0783	Belongs to the Dps family
FIV50_RS08200	COG0463	Glycosyl transferase, family 2
FIV50_RS08235	COG0022	dehydrogenase e1 component
FIV50_RS08240	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIV50_RS08250	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIV50_RS08260	COG1960	acyl-CoA dehydrogenase activity
FIV50_RS08275	COG0588	phosphoglycerate mutase activity
FIV50_RS08280	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FIV50_RS08290	COG2755	lipolytic protein G-D-S-L family
FIV50_RS08310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIV50_RS08315	COG1968	undecaprenyl-diphosphatase activity
FIV50_RS08350	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIV50_RS08355	COG0805	protein transport
FIV50_RS08360	COG4581	dead DEAH box helicase
FIV50_RS08375	COG0584	glycerophosphoryl diester phosphodiesterase
FIV50_RS08390	COG1028	Short-chain dehydrogenase reductase Sdr
FIV50_RS08410	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FIV50_RS08440	COG0628	permease
FIV50_RS08520	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FIV50_RS08550	COG4974	Belongs to the 'phage' integrase family
FIV50_RS08555	COG4974	Belongs to the 'phage' integrase family
FIV50_RS08605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIV50_RS08620	COG5290	Psort location Cytoplasmic, score
FIV50_RS08660	COG0456	acetyltransferase
FIV50_RS08660	COG0454	-acetyltransferase
FIV50_RS08680	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FIV50_RS08690	COG0477	Major facilitator Superfamily
FIV50_RS08695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIV50_RS08750	COG0069	glutamate synthase activity
FIV50_RS08750	COG0070	glutamate synthase
FIV50_RS08750	COG0067	glutamate synthase
FIV50_RS08755	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FIV50_RS08760	COG0159	tryptophan synthase activity
FIV50_RS08765	COG0133	tryptophan synthase activity
FIV50_RS08770	COG0134	indole-3-glycerol-phosphate synthase activity
FIV50_RS08785	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FIV50_RS08790	COG0107	imidazoleglycerol-phosphate synthase activity
FIV50_RS08795	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FIV50_RS08800	COG0140	phosphoribosyl-ATP diphosphatase activity
FIV50_RS08805	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FIV50_RS08815	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FIV50_RS08820	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FIV50_RS08825	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FIV50_RS08830	COG1758	RNA polymerase activity
FIV50_RS08835	COG0194	GDP metabolic process
FIV50_RS08840	COG0284	orotidine-5'-phosphate decarboxylase activity
FIV50_RS08845	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FIV50_RS08850	COG0505	Belongs to the CarA family
FIV50_RS08860	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FIV50_RS08865	COG0540	Belongs to the ATCase OTCase family
FIV50_RS08870	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FIV50_RS08880	COG2146	nitrite reductase [NAD(P)H] activity
FIV50_RS08880	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FIV50_RS08885	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FIV50_RS08890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FIV50_RS08895	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FIV50_RS08900	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FIV50_RS08905	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FIV50_RS08910	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FIV50_RS08915	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FIV50_RS08920	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FIV50_RS08930	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FIV50_RS08935	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FIV50_RS08945	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FIV50_RS08965	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIV50_RS08970	COG1196	nuclear chromosome segregation
FIV50_RS08980	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FIV50_RS08985	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIV50_RS08990	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIV50_RS09000	COG2255	four-way junction helicase activity
FIV50_RS09005	COG0632	four-way junction helicase activity
FIV50_RS09010	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FIV50_RS09015	COG0217	transcriptional regulatory protein
FIV50_RS09040	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FIV50_RS09045	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FIV50_RS09055	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FIV50_RS09065	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FIV50_RS09070	COG1742	UPF0060 membrane protein
FIV50_RS09080	COG0415	Belongs to the DNA photolyase family
FIV50_RS09115	COG2207	Transcriptional regulator
FIV50_RS09130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIV50_RS09135	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIV50_RS09140	COG1120	ATPase activity
FIV50_RS09165	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FIV50_RS09195	COG0183	Belongs to the thiolase family
FIV50_RS09200	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIV50_RS09200	COG1024	Enoyl-CoA hydratase
FIV50_RS09215	COG0277	FAD linked oxidase domain protein
FIV50_RS09235	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FIV50_RS09240	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FIV50_RS09255	COG0756	dUTP diphosphatase activity
FIV50_RS09280	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FIV50_RS09285	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FIV50_RS09295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIV50_RS09300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FIV50_RS09310	COG0187	DNA topoisomerase II activity
FIV50_RS09320	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FIV50_RS09325	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FIV50_RS09340	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FIV50_RS09350	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FIV50_RS09355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIV50_RS09360	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIV50_RS09375	COG0189	ligase activity
FIV50_RS09375	COG0569	domain protein
FIV50_RS09380	COG0189	ligase activity
FIV50_RS09380	COG4067	protein conserved in archaea
FIV50_RS09390	COG0174	glutamine synthetase
FIV50_RS09410	COG1597	lipid kinase activity
FIV50_RS09415	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FIV50_RS09420	COG0174	glutamine synthetase
FIV50_RS09450	COG3012	SEC-C Motif Domain Protein
FIV50_RS09470	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FIV50_RS09515	COG4786	Flagellar basal body rod
FIV50_RS09515	COG1256	bacterial-type flagellum assembly
FIV50_RS09525	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FIV50_RS09530	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FIV50_RS09535	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FIV50_RS09550	COG1338	Plays a role in the flagellum-specific transport system
FIV50_RS09590	COG2217	Heavy metal translocating P-type atpase
FIV50_RS09620	COG1157	protein secretion by the type III secretion system
FIV50_RS09630	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FIV50_RS09640	COG1677	Flagellar hook-basal body complex protein FliE
FIV50_RS09650	COG1815	bacterial-type flagellum-dependent cell motility
FIV50_RS09670	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FIV50_RS09680	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FIV50_RS09710	COG0733	neurotransmitter:sodium symporter activity
FIV50_RS09735	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FIV50_RS09750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FIV50_RS09755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FIV50_RS09765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIV50_RS09795	COG0254	rRNA binding
FIV50_RS09800	COG1119	ATPase activity
FIV50_RS09805	COG0297	glycogen (starch) synthase activity
FIV50_RS09810	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FIV50_RS09815	COG3830	Belongs to the UPF0237 family
FIV50_RS09815	COG0560	Phosphoserine phosphatase
FIV50_RS09825	COG1028	Short-chain dehydrogenase reductase Sdr
FIV50_RS09850	COG0259	pyridoxamine-phosphate oxidase activity
FIV50_RS09855	COG0488	(ABC) transporter
FIV50_RS09875	COG2197	response regulator
FIV50_RS09890	COG1122	ATPase activity
FIV50_RS09895	COG1268	BioY protein
FIV50_RS09915	COG2151	metal-sulfur cluster biosynthetic enzyme
FIV50_RS09920	COG0396	ATPase activity
FIV50_RS09940	COG1612	heme a metabolic process
FIV50_RS09950	COG0109	protoheme IX farnesyltransferase activity
FIV50_RS09955	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FIV50_RS09960	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FIV50_RS09965	COG0166	Belongs to the GPI family
FIV50_RS09980	COG0363	glucosamine-6-phosphate deaminase activity
FIV50_RS10005	COG4172	Belongs to the ABC transporter superfamily
FIV50_RS10010	COG0358	DNA primase activity
FIV50_RS10025	COG0386	Belongs to the glutathione peroxidase family
FIV50_RS10045	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FIV50_RS10050	COG1381	Involved in DNA repair and RecF pathway recombination
FIV50_RS10060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FIV50_RS10070	COG0604	alcohol dehydrogenase
FIV50_RS10070	COG1028	Short-chain dehydrogenase reductase Sdr
FIV50_RS10070	COG3321	synthase
FIV50_RS10090	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FIV50_RS10100	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FIV50_RS10110	COG0537	adenosine 5'-monophosphoramidase activity
FIV50_RS10115	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FIV50_RS10120	COG0484	heat shock protein binding
FIV50_RS10125	COG1420	regulation of RNA biosynthetic process
FIV50_RS10145	COG0481	GTPase activity
FIV50_RS10180	COG0268	Binds directly to 16S ribosomal RNA
FIV50_RS10195	COG3152	Membrane
FIV50_RS10230	COG1555	photosystem II stabilization
FIV50_RS10230	COG1596	polysaccharide export
FIV50_RS10235	COG0495	leucyl-tRNA aminoacylation
FIV50_RS10240	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FIV50_RS10240	COG0512	Glutamine amidotransferase of anthranilate synthase
FIV50_RS10260	COG1472	Belongs to the glycosyl hydrolase 3 family
FIV50_RS10315	COG0799	negative regulation of ribosome biogenesis
FIV50_RS10325	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FIV50_RS10335	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FIV50_RS10340	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FIV50_RS10345	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FIV50_RS10350	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FIV50_RS10355	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FIV50_RS10365	COG1530	ribonuclease E activity
FIV50_RS10375	COG0105	UTP biosynthetic process
FIV50_RS10385	COG0285	dihydrofolate synthase activity
FIV50_RS10390	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FIV50_RS10410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIV50_RS10420	COG0747	negative chemotaxis
FIV50_RS10425	COG0525	valine-tRNA ligase activity
FIV50_RS10450	COG1063	alcohol dehydrogenase
FIV50_RS10460	COG0339	signal peptide processing
FIV50_RS10470	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FIV50_RS10475	COG1012	belongs to the aldehyde dehydrogenase family
FIV50_RS10480	COG1012	belongs to the aldehyde dehydrogenase family
FIV50_RS10485	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FIV50_RS10490	COG2390	Transcriptional regulator
FIV50_RS10495	COG0740	serine-type endopeptidase activity
FIV50_RS10500	COG0740	serine-type endopeptidase activity
FIV50_RS10510	COG0544	peptidyl-prolyl cis-trans isomerase activity
FIV50_RS10535	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FIV50_RS10540	COG0149	triose-phosphate isomerase activity
FIV50_RS10545	COG0126	phosphoglycerate kinase activity
FIV50_RS10550	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FIV50_RS10555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FIV50_RS10560	COG1481	regulation of sporulation
FIV50_RS10565	COG1660	Displays ATPase and GTPase activities
FIV50_RS10570	COG0322	excinuclease ABC activity
FIV50_RS10590	COG0714	Associated with various cellular activities
FIV50_RS10605	COG1846	Transcriptional regulator
FIV50_RS10620	COG0556	nucleotide-excision repair
FIV50_RS10630	COG2814	Major facilitator Superfamily
FIV50_RS10635	COG0237	dephospho-CoA kinase activity
FIV50_RS10640	COG1832	CoA-binding protein
FIV50_RS10650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIV50_RS10655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIV50_RS10670	COG0539	negative regulation of cytoplasmic translation
FIV50_RS10675	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIV50_RS10680	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FIV50_RS10680	COG1796	DNA polymerase
FIV50_RS10685	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FIV50_RS10690	COG1845	cytochrome c oxidase, subunit III
FIV50_RS10695	COG2010	Cytochrome c
FIV50_RS10700	COG0723	plastoquinol--plastocyanin reductase activity
FIV50_RS10705	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FIV50_RS10730	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FIV50_RS10735	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FIV50_RS10755	COG0167	dihydroorotate dehydrogenase activity
FIV50_RS10760	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FIV50_RS10765	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FIV50_RS10795	COG3599	regulation of cell shape
FIV50_RS10805	COG1799	cell septum assembly
FIV50_RS10810	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FIV50_RS10815	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FIV50_RS10820	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FIV50_RS10825	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FIV50_RS10830	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FIV50_RS10840	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FIV50_RS10845	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FIV50_RS10855	COG0768	penicillin binding
FIV50_RS10865	COG0275	rRNA processing
FIV50_RS10870	COG2001	Belongs to the MraZ family
FIV50_RS10880	COG0142	geranyltranstransferase activity
FIV50_RS10890	COG3942	CHAP domain
FIV50_RS10890	COG1388	LysM domain
FIV50_RS10895	COG2815	serine threonine protein kinase
FIV50_RS10895	COG0515	serine threonine protein kinase
FIV50_RS10900	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FIV50_RS10905	COG0204	Acyl-transferase
FIV50_RS10910	COG1022	Amp-dependent synthetase and ligase
FIV50_RS10925	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FIV50_RS10930	COG1192	Involved in chromosome partitioning
FIV50_RS10945	COG1716	ATPase activity
FIV50_RS10950	COG2372	response to copper ion
FIV50_RS10995	COG0587	DNA-directed DNA polymerase activity
FIV50_RS11015	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FIV50_RS11065	COG1051	belongs to the nudix hydrolase family
FIV50_RS11070	COG1160	GTP binding
FIV50_RS11075	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FIV50_RS11090	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FIV50_RS11095	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FIV50_RS11110	COG0494	nUDIX hydrolase
FIV50_RS11115	COG0504	CTP synthase activity
FIV50_RS11120	COG0497	DNA recombination
FIV50_RS11125	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FIV50_RS11135	COG0647	UMP catabolic process
FIV50_RS11160	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIV50_RS11170	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FIV50_RS11195	COG0165	Argininosuccinate lyase
FIV50_RS11200	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FIV50_RS11205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FIV50_RS11210	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FIV50_RS11215	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FIV50_RS11220	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FIV50_RS11225	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FIV50_RS11225	COG0352	thiamine-phosphate diphosphorylase activity
FIV50_RS11225	COG0351	phosphomethylpyrimidine kinase
FIV50_RS11230	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FIV50_RS11245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIV50_RS11245	COG0072	phenylalanine-tRNA ligase activity
FIV50_RS11250	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FIV50_RS11255	COG0765	amino acid transport
FIV50_RS11260	COG0765	amino acid transport
FIV50_RS11265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIV50_RS11270	COG1126	abc transporter atp-binding protein
FIV50_RS11280	COG5002	protein histidine kinase activity
FIV50_RS11285	COG0745	RESPONSE REGULATOR receiver
FIV50_RS11290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIV50_RS11295	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FIV50_RS11300	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FIV50_RS11305	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FIV50_RS11320	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FIV50_RS11330	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FIV50_RS11335	COG0131	Imidazoleglycerol-phosphate dehydratase
FIV50_RS11340	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FIV50_RS11350	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FIV50_RS11360	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FIV50_RS11365	COG2177	Part of the ABC transporter FtsEX involved in
FIV50_RS11370	COG2884	Cell division ATP-binding protein ftsE
FIV50_RS11385	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FIV50_RS11440	COG0586	Pfam SNARE associated Golgi protein
FIV50_RS11445	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FIV50_RS11465	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FIV50_RS11470	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FIV50_RS11475	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FIV50_RS11500	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FIV50_RS11510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIV50_RS11535	COG2197	response regulator
FIV50_RS11540	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FIV50_RS11545	COG0424	maF-like protein
FIV50_RS11550	COG4770	biotin carboxylase activity
FIV50_RS11570	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIV50_RS11595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FIV50_RS11600	COG2213	PTS system mannitol-specific
FIV50_RS11605	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIV50_RS11610	COG0246	Mannitol dehydrogenase
FIV50_RS11615	COG2072	flavoprotein involved in K transport
FIV50_RS11620	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FIV50_RS11625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIV50_RS11635	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FIV50_RS11650	COG1079	Belongs to the binding-protein-dependent transport system permease family
FIV50_RS11655	COG4603	Belongs to the binding-protein-dependent transport system permease family
FIV50_RS11660	COG3845	ABC transporter
FIV50_RS11665	COG1744	ABC transporter substrate-binding protein PnrA-like
FIV50_RS11675	COG2009	succinate dehydrogenase
FIV50_RS11705	COG0180	Tryptophanyl-tRNA synthetase
FIV50_RS11715	COG0193	aminoacyl-tRNA hydrolase activity
FIV50_RS11720	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FIV50_RS11725	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FIV50_RS11730	COG1136	(ABC) transporter
FIV50_RS11730	COG0577	efflux transmembrane transporter activity
FIV50_RS11740	COG0745	RESPONSE REGULATOR receiver
FIV50_RS11745	COG2205	protein histidine kinase activity
FIV50_RS11750	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIV50_RS11750	COG1017	nitric oxide dioxygenase activity
FIV50_RS11765	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FIV50_RS11770	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FIV50_RS11780	COG1846	Transcriptional regulator
FIV50_RS11785	COG0564	pseudouridine synthase activity
FIV50_RS11795	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FIV50_RS11810	COG0488	(ABC) transporter
FIV50_RS11820	COG0596	Alpha beta hydrolase
FIV50_RS11850	COG4214	carbohydrate transport
FIV50_RS11865	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FIV50_RS11870	COG0667	Aldo Keto reductase
FIV50_RS11875	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FIV50_RS11885	COG0084	hydrolase, TatD family'
FIV50_RS11890	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIV50_RS11900	COG2723	6-phospho-beta-galactosidase activity
FIV50_RS11915	COG0601	transmembrane transport
FIV50_RS11920	COG4166	transmembrane transport
FIV50_RS11930	COG2226	methyltransferase
FIV50_RS11945	COG1113	amino acid transport
FIV50_RS11950	COG1331	Highly conserved protein containing a thioredoxin domain
FIV50_RS11970	COG1643	Atp-dependent helicase
FIV50_RS12010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIV50_RS12015	COG4172	Belongs to the ABC transporter superfamily
FIV50_RS12020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIV50_RS12025	COG0601	transmembrane transport
FIV50_RS12030	COG0747	negative chemotaxis
FIV50_RS12035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIV50_RS12075	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV50_RS12080	COG1129	ABC transporter
FIV50_RS12085	COG0673	inositol 2-dehydrogenase activity
FIV50_RS12095	COG0673	inositol 2-dehydrogenase activity
FIV50_RS12125	COG4989	oxidoreductase activity
FIV50_RS12170	COG0166	Belongs to the GPI family
FIV50_RS12195	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FIV50_RS12230	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIV50_RS12245	COG2076	Multidrug Resistance protein
FIV50_RS12260	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FIV50_RS12265	COG0142	geranyltranstransferase activity
FIV50_RS12275	COG1233	COG1233 Phytoene dehydrogenase and related
FIV50_RS12290	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FIV50_RS12295	COG2409	Drug exporters of the RND superfamily
FIV50_RS12320	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FIV50_RS12345	COG1061	Type III restriction enzyme res subunit
FIV50_RS12350	COG0745	RESPONSE REGULATOR receiver
FIV50_RS12355	COG2205	protein histidine kinase activity
FIV50_RS12365	COG0459	protein refolding
FIV50_RS12385	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIV50_RS12405	COG2315	Protein conserved in bacteria
FIV50_RS12410	COG1131	(ABC) transporter
FIV50_RS12420	COG4585	Histidine kinase
FIV50_RS12425	COG2197	response regulator
FIV50_RS12450	COG3842	ATPase activity
FIV50_RS12460	COG2910	NAD(P)H-binding
FIV50_RS12465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIV50_RS12470	COG0215	cysteine-tRNA ligase activity
FIV50_RS12480	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FIV50_RS12480	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FIV50_RS12500	COG5002	protein histidine kinase activity
FIV50_RS12510	COG0588	phosphoglycerate mutase activity
FIV50_RS12520	COG0354	folic acid binding
FIV50_RS12525	COG4044	May play a role in the intracellular transport of hydrophobic ligands
FIV50_RS12535	COG0745	RESPONSE REGULATOR receiver
FIV50_RS12540	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FIV50_RS12565	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIV50_RS12600	COG0693	protein deglycase activity
FIV50_RS12625	COG1335	isochorismatase
FIV50_RS12640	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FIV50_RS12645	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FIV50_RS12650	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FIV50_RS12650	COG1754	DNA topoisomerase type I activity
FIV50_RS12680	COG4974	Belongs to the 'phage' integrase family
FIV50_RS12710	COG0252	asparaginase activity
FIV50_RS12715	COG4948	Mandelate Racemase Muconate Lactonizing
FIV50_RS12725	COG0395	ABC-type sugar transport system, permease component
FIV50_RS12730	COG1175	transmembrane transport
FIV50_RS12735	COG1653	transport
FIV50_RS12770	COG0667	Aldo Keto reductase
FIV50_RS12780	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FIV50_RS12870	COG0758	DNA mediated transformation
FIV50_RS12885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIV50_RS12900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FIV50_RS12940	COG1435	thymidine kinase activity
FIV50_RS12945	COG0579	oxidoreductase
FIV50_RS12965	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FIV50_RS12990	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FIV50_RS13020	COG0714	Associated with various cellular activities
FIV50_RS13050	COG1131	(ABC) transporter
FIV50_RS13060	COG2226	methyltransferase
FIV50_RS13070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIV50_RS13095	COG0456	acetyltransferase
FIV50_RS13095	COG0454	-acetyltransferase
FIV50_RS13105	COG2814	Major facilitator Superfamily
FIV50_RS13120	COG0395	ABC-type sugar transport system, permease component
FIV50_RS13125	COG1175	transmembrane transport
FIV50_RS13130	COG1653	transport
FIV50_RS13135	COG1609	Transcriptional regulator
FIV50_RS13140	COG0222	ribosome binding
FIV50_RS13145	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FIV50_RS13150	COG3387	PFAM Glycoside hydrolase 15-related
FIV50_RS13155	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FIV50_RS13200	COG1126	abc transporter atp-binding protein
FIV50_RS13205	COG0765	amino acid transport
FIV50_RS13210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIV50_RS13215	COG0081	regulation of translation
FIV50_RS13220	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FIV50_RS13240	COG0326	Molecular chaperone. Has ATPase activity
FIV50_RS13250	COG0028	Belongs to the TPP enzyme family
FIV50_RS13255	COG1012	belongs to the aldehyde dehydrogenase family
FIV50_RS13295	COG3639	organic phosphonate transmembrane transporter activity
FIV50_RS13305	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FIV50_RS13310	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FIV50_RS13325	COG2814	Major facilitator Superfamily
FIV50_RS13330	COG1396	sequence-specific DNA binding
FIV50_RS13340	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FIV50_RS13360	COG0686	Belongs to the AlaDH PNT family
FIV50_RS13365	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIV50_RS13370	COG0251	oxidation-reduction process
FIV50_RS13400	COG1522	sequence-specific DNA binding
FIV50_RS13405	COG1113	amino acid transport
FIV50_RS13410	COG0436	Aminotransferase
FIV50_RS13455	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FIV50_RS13465	COG2030	dehydratase
FIV50_RS13470	COG1929	Belongs to the glycerate kinase type-1 family
FIV50_RS13485	COG2205	protein histidine kinase activity
FIV50_RS13495	COG0730	response to heat
FIV50_RS13500	COG0318	PFAM AMP-dependent synthetase and ligase
FIV50_RS13505	COG0203	ribosomal protein L17
FIV50_RS13510	COG0202	RNA polymerase activity
FIV50_RS13515	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FIV50_RS13520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FIV50_RS13530	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FIV50_RS13545	COG0024	Methionine aminopeptidase
FIV50_RS13550	COG0563	adenylate kinase activity
FIV50_RS13560	COG0200	Binds to the 23S rRNA
FIV50_RS13565	COG1841	ribosomal large subunit assembly
FIV50_RS13570	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FIV50_RS13575	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FIV50_RS13580	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FIV50_RS13585	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FIV50_RS13590	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FIV50_RS13595	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FIV50_RS13600	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FIV50_RS13605	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FIV50_RS13610	COG0255	Belongs to the universal ribosomal protein uL29 family
FIV50_RS13615	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FIV50_RS13620	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FIV50_RS13625	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FIV50_RS13630	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FIV50_RS13635	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FIV50_RS13640	COG0089	rRNA binding
FIV50_RS13645	COG0088	Forms part of the polypeptide exit tunnel
FIV50_RS13650	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FIV50_RS13655	COG0051	transcription antitermination factor activity, RNA binding
FIV50_RS13675	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FIV50_RS13690	COG0438	transferase activity, transferring glycosyl groups
FIV50_RS13695	COG0438	transferase activity, transferring glycosyl groups
FIV50_RS13725	COG1215	transferase activity, transferring glycosyl groups
FIV50_RS13730	COG1216	Glycosyl transferase, family 2
FIV50_RS13745	COG1216	Glycosyl transferase, family 2
FIV50_RS13750	COG0463	Glycosyl transferase, family 2
FIV50_RS13775	COG2801	Transposase and inactivated derivatives
FIV50_RS13775	COG3415	Transposase
FIV50_RS13785	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FIV50_RS13790	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FIV50_RS13795	COG0049	tRNA binding
FIV50_RS13800	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FIV50_RS13810	COG3655	Transcriptional regulator
FIV50_RS13835	COG3833	ABC-type maltose transport systems, permease component
FIV50_RS13840	COG1175	transmembrane transport
FIV50_RS13845	COG2182	Extracellular solute-binding protein
FIV50_RS13850	COG1666	GTP binding
FIV50_RS13875	COG0142	geranyltranstransferase activity
FIV50_RS13880	COG2226	methyltransferase
FIV50_RS13890	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FIV50_RS13895	COG2326	polyphosphate kinase activity
FIV50_RS13900	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FIV50_RS13920	COG2133	pyrroloquinoline quinone binding
FIV50_RS13925	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FIV50_RS13955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIV50_RS13960	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIV50_RS13965	COG1120	ATPase activity
FIV50_RS13970	COG1132	(ABC) transporter
FIV50_RS13975	COG1132	(ABC) transporter
FIV50_RS14020	COG2089	acid synthase
FIV50_RS14025	COG1083	cytidylyl-transferase
FIV50_RS14050	COG1575	Belongs to the MenA family. Type 1 subfamily
FIV50_RS14060	COG0662	Cupin 2, conserved barrel domain protein
FIV50_RS14060	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FIV50_RS14070	COG1522	sequence-specific DNA binding
FIV50_RS14105	COG0488	(ABC) transporter
FIV50_RS14110	COG1201	RNA secondary structure unwinding
FIV50_RS14135	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FIV50_RS14160	COG0475	glutathione-regulated potassium exporter activity
FIV50_RS14195	COG5006	permease, DMT superfamily
FIV50_RS14200	COG1028	Short-chain dehydrogenase reductase Sdr
FIV50_RS14210	COG1058	Belongs to the CinA family
FIV50_RS14210	COG1546	Belongs to the CinA family
FIV50_RS14230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIV50_RS14235	COG3639	organic phosphonate transmembrane transporter activity
FIV50_RS14240	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FIV50_RS14245	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FIV50_RS14250	COG2188	Transcriptional regulator
FIV50_RS14280	COG1362	aminopeptidase activity
FIV50_RS14305	COG0657	acetylesterase activity
FIV50_RS14310	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FIV50_RS14310	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FIV50_RS14320	COG2957	Belongs to the agmatine deiminase family
FIV50_RS14330	COG3483	tryptophan 2,3-dioxygenase activity
FIV50_RS14350	COG1609	Transcriptional regulator
FIV50_RS14365	COG0395	ABC-type sugar transport system, permease component
FIV50_RS14400	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FIV50_RS14460	COG3546	catalase activity
FIV50_RS14475	COG1902	pentaerythritol trinitrate reductase activity
FIV50_RS14500	COG0477	Major facilitator Superfamily
FIV50_RS14535	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FIV50_RS14610	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FIV50_RS14620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIV50_RS14625	COG2197	response regulator
FIV50_RS14630	COG4585	Histidine kinase
FIV50_RS14640	COG1131	(ABC) transporter
FIV50_RS14650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIV50_RS14655	COG0402	S-adenosylhomocysteine deaminase activity
FIV50_RS14680	COG2200	EAL domain
FIV50_RS14700	COG2066	Belongs to the glutaminase family
FIV50_RS14730	COG0673	inositol 2-dehydrogenase activity
FIV50_RS14740	COG1609	Transcriptional regulator
FIV50_RS14760	COG0673	inositol 2-dehydrogenase activity
FIV50_RS14775	COG0395	ABC-type sugar transport system, permease component
FIV50_RS14780	COG1175	transmembrane transport
FIV50_RS14820	COG1175	transmembrane transport
FIV50_RS14850	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FIV50_RS14915	COG1132	(ABC) transporter
FIV50_RS14920	COG4988	ABC transporter
FIV50_RS14925	COG1294	oxidase, subunit
FIV50_RS14930	COG1271	oxidase subunit
FIV50_RS14940	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FIV50_RS14955	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FIV50_RS14975	COG3655	Transcriptional regulator
FIV50_RS15000	COG1823	symporter activity
FIV50_RS15005	COG0025	NhaP-type Na H and K H
FIV50_RS15010	COG0789	Transcriptional regulator
FIV50_RS15020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIV50_RS15040	COG0746	molybdenum cofactor guanylyltransferase activity
FIV50_RS15065	COG1929	Belongs to the glycerate kinase type-1 family
FIV50_RS15070	COG1609	Transcriptional regulator
FIV50_RS15090	COG0673	inositol 2-dehydrogenase activity
FIV50_RS15095	COG1609	Transcriptional regulator
FIV50_RS15105	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FIV50_RS15115	COG2211	Major facilitator Superfamily
FIV50_RS15125	COG1940	carbohydrate kinase activity
FIV50_RS15130	COG0456	acetyltransferase
FIV50_RS15135	COG1012	belongs to the aldehyde dehydrogenase family
FIV50_RS15145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIV50_RS15175	COG0697	spore germination
FIV50_RS15195	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FIV50_RS15200	COG0095	Lipoate-protein ligase
FIV50_RS15210	COG2267	carboxylic ester hydrolase activity
FIV50_RS15220	COG1846	Transcriptional regulator
FIV50_RS15235	COG2072	flavoprotein involved in K transport
FIV50_RS15240	COG0765	amino acid transport
FIV50_RS15245	COG0765	amino acid transport
FIV50_RS15250	COG1126	abc transporter atp-binding protein
FIV50_RS15260	COG1028	Short-chain dehydrogenase reductase Sdr
FIV50_RS15265	COG1028	Short-chain dehydrogenase reductase Sdr
FIV50_RS15270	COG0583	DNA-binding transcription factor activity
FIV50_RS15280	COG1929	Belongs to the glycerate kinase type-1 family
FIV50_RS15290	COG0583	DNA-binding transcription factor activity
FIV50_RS15295	COG0471	metal ion transport
FIV50_RS15305	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIV50_RS15310	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIV50_RS15335	COG0596	Alpha beta hydrolase
FIV50_RS15345	COG1522	sequence-specific DNA binding
FIV50_RS15350	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIV50_RS15365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIV50_RS15375	COG1028	Short-chain dehydrogenase reductase Sdr
FIV50_RS15385	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FIV50_RS15395	COG0833	amino acid
FIV50_RS15400	COG1937	Protein conserved in bacteria
FIV50_RS15405	COG2733	membrane
FIV50_RS15410	COG1228	amidohydrolase
FIV50_RS15415	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FIV50_RS15420	COG2986	histidine ammonia-lyase
FIV50_RS15445	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FIV50_RS15450	COG1834	amidinotransferase
FIV50_RS15455	COG0604	alcohol dehydrogenase
FIV50_RS15460	COG1476	TRANSCRIPTIONal
FIV50_RS15470	COG1012	belongs to the aldehyde dehydrogenase family
FIV50_RS15495	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FIV50_RS15550	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV50_RS15555	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIV50_RS15570	COG1609	Transcriptional regulator
FIV50_RS15580	COG0667	Aldo Keto reductase
FIV50_RS15590	COG0183	Belongs to the thiolase family
FIV50_RS15615	COG2017	converts alpha-aldose to the beta-anomer
FIV50_RS15620	COG2160	L-arabinose isomerase activity
FIV50_RS15635	COG1609	Transcriptional regulator
FIV50_RS15640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIV50_RS15655	COG1175	transmembrane transport
FIV50_RS15660	COG0395	ABC-type sugar transport system, permease component
FIV50_RS15715	COG1609	Transcriptional regulator
FIV50_RS15720	COG0277	FAD linked oxidase domain protein
FIV50_RS15725	COG1609	Transcriptional regulator
FIV50_RS15735	COG1175	transmembrane transport
FIV50_RS15740	COG0395	ABC-type sugar transport system, permease component
FIV50_RS15765	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FIV50_RS15770	COG2079	MmgE PrpD family protein
FIV50_RS15795	COG3618	amidohydrolase
FIV50_RS15800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIV50_RS15815	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FIV50_RS15825	COG0454	-acetyltransferase
FIV50_RS15830	COG2188	Transcriptional regulator
FIV50_RS15845	COG1175	transmembrane transport
FIV50_RS15850	COG0395	ABC-type sugar transport system, permease component
FIV50_RS15855	COG0667	Aldo Keto reductase
FIV50_RS15875	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FIV50_RS15880	COG0222	ribosome binding
FIV50_RS15900	COG0300	oxidoreductase activity
FIV50_RS15920	COG1253	flavin adenine dinucleotide binding
FIV50_RS15935	COG4172	Belongs to the ABC transporter superfamily
FIV50_RS15940	COG4721	ABC-type cobalt transport system, permease component
FIV50_RS15960	COG1024	Enoyl-CoA hydratase
FIV50_RS15980	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FIV50_RS15995	COG0181	hydroxymethylbilane synthase activity
FIV50_RS16000	COG3253	May function as heme-dependent peroxidase
FIV50_RS16025	COG0640	Transcriptional regulator
FIV50_RS16030	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FIV50_RS16035	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FIV50_RS16055	COG0423	glycine-tRNA ligase activity
FIV50_RS16070	COG3104	oligopeptide transport
FIV50_RS16075	COG0477	Major facilitator Superfamily
FIV50_RS16085	COG3590	peptidase
FIV50_RS16095	COG0534	Mate efflux family protein
FIV50_RS16115	COG3401	FG-GAP repeat protein
FIV50_RS16140	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FIV50_RS16150	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FIV50_RS16160	COG0561	phosphatase activity
FIV50_RS16185	COG3135	benzoate transporter
FIV50_RS16195	COG4152	abc transporter atp-binding protein
FIV50_RS16200	COG1668	transmembrane transport
FIV50_RS16205	COG1012	belongs to the aldehyde dehydrogenase family
FIV50_RS16210	COG0583	DNA-binding transcription factor activity
FIV50_RS16220	COG0542	response to heat
FIV50_RS16295	COG1609	Transcriptional regulator
FIV50_RS16310	COG1175	transmembrane transport
FIV50_RS16315	COG0395	ABC-type sugar transport system, permease component
FIV50_RS16320	COG3537	Alpha-1,2-mannosidase
FIV50_RS16330	COG0318	PFAM AMP-dependent synthetase and ligase
FIV50_RS16340	COG1215	transferase activity, transferring glycosyl groups
FIV50_RS16345	COG1366	Belongs to the anti-sigma-factor antagonist family
FIV50_RS16355	COG2259	Doxx family
FIV50_RS16365	COG1233	COG1233 Phytoene dehydrogenase and related
FIV50_RS16370	COG0789	Transcriptional regulator
FIV50_RS16375	COG0484	heat shock protein binding
FIV50_RS16380	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FIV50_RS16385	COG0443	Heat shock 70 kDa protein
FIV50_RS16390	COG0492	ferredoxin-NADP+ reductase activity
FIV50_RS16405	COG0662	Cupin 2, conserved barrel domain protein
FIV50_RS16405	COG2207	Transcriptional regulator
FIV50_RS16435	COG0477	Major facilitator Superfamily
FIV50_RS16480	COG0717	Belongs to the dCTP deaminase family
FIV50_RS16510	COG1022	Amp-dependent synthetase and ligase
FIV50_RS16550	COG0457	Tetratricopeptide repeat
FIV50_RS16565	COG3237	CsbD-like
FIV50_RS16590	COG1302	Protein conserved in bacteria
FIV50_RS16615	COG1349	DNA-binding transcription factor activity
FIV50_RS16625	COG0531	amino acid
FIV50_RS16635	COG0598	Magnesium transport protein CorA
FIV50_RS16650	COG5398	heme oxygenase
FIV50_RS16655	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FIV50_RS16670	COG0776	regulation of translation
FIV50_RS16675	COG1309	transcriptional regulator
FIV50_RS16690	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FIV50_RS16695	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FIV50_RS16700	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FIV50_RS16715	COG0395	ABC-type sugar transport system, permease component
FIV50_RS16745	COG2094	Belongs to the DNA glycosylase MPG family
FIV50_RS16760	COG0701	Predicted permease
FIV50_RS16765	COG0735	belongs to the Fur family
FIV50_RS16770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIV50_RS16775	COG1121	(ABC) transporter
FIV50_RS16785	COG0366	Alpha amylase catalytic
FIV50_RS16795	COG1175	transmembrane transport
FIV50_RS16800	COG2182	Extracellular solute-binding protein
FIV50_RS16830	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIV50_RS16835	COG0022	dehydrogenase e1 component
FIV50_RS16845	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FIV50_RS16865	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FIV50_RS16870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FIV50_RS16875	COG0477	Major facilitator Superfamily
FIV50_RS16905	COG1063	alcohol dehydrogenase
FIV50_RS16910	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIV50_RS16915	COG1846	Transcriptional regulator
FIV50_RS16950	COG0740	serine-type endopeptidase activity
FIV50_RS16955	COG0740	serine-type endopeptidase activity
FIV50_RS16960	COG1607	acyl-coa hydrolase
FIV50_RS16965	COG0626	cystathionine gamma-synthase activity
FIV50_RS16990	COG0534	Mate efflux family protein
FIV50_RS16995	COG1113	amino acid transport
FIV50_RS17000	COG0667	Aldo Keto reductase
FIV50_RS17005	COG1739	Uncharacterized protein family UPF0029
FIV50_RS17010	COG0484	heat shock protein binding
FIV50_RS17015	COG1609	Transcriptional regulator
FIV50_RS17025	COG1175	transmembrane transport
FIV50_RS17040	COG0406	alpha-ribazole phosphatase activity
FIV50_RS17065	COG0596	Alpha beta hydrolase
FIV50_RS17070	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIV50_RS17075	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIV50_RS17080	COG2354	Protein conserved in bacteria
FIV50_RS17095	COG1595	DNA-templated transcription, initiation
FIV50_RS17125	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FIV50_RS17145	COG0745	RESPONSE REGULATOR receiver
FIV50_RS17150	COG2205	protein histidine kinase activity
FIV50_RS17175	COG1028	Short-chain dehydrogenase reductase Sdr
FIV50_RS17180	COG3591	Belongs to the peptidase S1B family
FIV50_RS17180	COG1864	DNA RNA non-specific endonuclease
FIV50_RS17190	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIV50_RS17205	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FIV50_RS17230	COG1484	DNA-dependent DNA replication
FIV50_RS17265	COG0305	Participates in initiation and elongation during chromosome replication
FIV50_RS17300	COG0359	binds to the 23S rRNA
FIV50_RS17305	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FIV50_RS17315	COG0360	Binds together with S18 to 16S ribosomal RNA
FIV50_RS17335	COG0444	Belongs to the ABC transporter superfamily
FIV50_RS17340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIV50_RS17345	COG0601	transmembrane transport
FIV50_RS17380	COG3609	addiction module antidote protein, CC2985 family
FIV50_RS17420	COG0180	Tryptophanyl-tRNA synthetase
FIV50_RS17430	COG1012	belongs to the aldehyde dehydrogenase family
FIV50_RS17445	COG0617	tRNA 3'-terminal CCA addition
FIV50_RS17465	COG2890	protein-(glutamine-N5) methyltransferase activity
FIV50_RS17480	COG0492	ferredoxin-NADP+ reductase activity
FIV50_RS17485	COG3118	belongs to the thioredoxin family
FIV50_RS17490	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FIV50_RS17500	COG0477	Major facilitator Superfamily
FIV50_RS17510	COG1192	Involved in chromosome partitioning
FIV50_RS17525	COG0357	Ribosomal RNA small subunit methyltransferase G
FIV50_RS17530	COG0706	membrane insertase activity
FIV50_RS17535	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FIV50_RS17540	COG0594	ribonuclease P activity
FIV50_RS17545	COG0230	Belongs to the bacterial ribosomal protein bL34 family