locus-tag	class	description
JVX92_RS00025	COG0647	UMP catabolic process
JVX92_RS00045	COG1120	ATPase activity
JVX92_RS00050	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX92_RS00055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX92_RS00060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JVX92_RS00070	COG0693	protein deglycase activity
JVX92_RS00080	COG2814	Major facilitator Superfamily
JVX92_RS00090	COG1132	(ABC) transporter
JVX92_RS00115	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JVX92_RS00120	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JVX92_RS00135	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JVX92_RS00140	COG0509	glycine decarboxylation via glycine cleavage system
JVX92_RS00145	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JVX92_RS00145	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JVX92_RS00155	COG0747	negative chemotaxis
JVX92_RS00175	COG4172	Belongs to the ABC transporter superfamily
JVX92_RS00180	COG1217	gtp-binding protein TYPA
JVX92_RS00220	COG1834	amidinotransferase
JVX92_RS00225	COG2326	polyphosphate kinase activity
JVX92_RS00230	COG2171	N-acyltransferase activity
JVX92_RS00235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JVX92_RS00255	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JVX92_RS00270	COG2239	Acts as a magnesium transporter
JVX92_RS00285	COG0006	proline dipeptidase activity
JVX92_RS00300	COG3739	integral membrane protein
JVX92_RS00310	COG0513	Belongs to the DEAD box helicase family
JVX92_RS00335	COG0210	DNA helicase
JVX92_RS00360	COG3480	Lon protease (S16) C-terminal proteolytic domain
JVX92_RS00365	COG1615	UPF0182 protein
JVX92_RS00415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JVX92_RS00425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JVX92_RS00430	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JVX92_RS00435	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JVX92_RS00450	COG3281	Trehalose synthase
JVX92_RS00490	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JVX92_RS00495	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JVX92_RS00500	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JVX92_RS00515	COG1793	dna ligase
JVX92_RS00515	COG3285	dna ligase
JVX92_RS00520	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JVX92_RS00525	COG0586	Pfam SNARE associated Golgi protein
JVX92_RS00795	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JVX92_RS00800	COG2884	Cell division ATP-binding protein ftsE
JVX92_RS00805	COG2177	Part of the ABC transporter FtsEX involved in
JVX92_RS00810	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JVX92_RS00830	COG0483	inositol monophosphate 1-phosphatase activity
JVX92_RS00850	COG2814	Major facilitator Superfamily
JVX92_RS00885	COG0318	PFAM AMP-dependent synthetase and ligase
JVX92_RS00890	COG1309	transcriptional regulator
JVX92_RS00895	COG1028	Short-chain dehydrogenase reductase Sdr
JVX92_RS00900	COG2267	carboxylic ester hydrolase activity
JVX92_RS00945	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
JVX92_RS00955	COG0129	dihydroxy-acid dehydratase activity
JVX92_RS00960	COG0028	Belongs to the TPP enzyme family
JVX92_RS00970	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JVX92_RS00975	COG3142	Participates in the control of copper homeostasis
JVX92_RS01000	COG0477	Major facilitator Superfamily
JVX92_RS01005	COG0473	3-isopropylmalate dehydrogenase activity
JVX92_RS01010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JVX92_RS01015	COG0179	Fumarylacetoacetate (FAA) hydrolase
JVX92_RS01030	COG0583	DNA-binding transcription factor activity
JVX92_RS01035	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JVX92_RS01040	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JVX92_RS01085	COG2197	response regulator
JVX92_RS01105	COG1597	lipid kinase activity
JVX92_RS01120	COG1349	DNA-binding transcription factor activity
JVX92_RS01130	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JVX92_RS01130	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JVX92_RS01130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JVX92_RS01200	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JVX92_RS01205	COG0066	3-isopropylmalate dehydratase activity
JVX92_RS01210	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JVX92_RS01220	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JVX92_RS01225	COG1181	Belongs to the D-alanine--D-alanine ligase family
JVX92_RS01240	COG0742	ribosomal rna small subunit methyltransferase
JVX92_RS01255	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JVX92_RS01265	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JVX92_RS01270	COG0571	ribonuclease III activity
JVX92_RS01275	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JVX92_RS01285	COG1196	nuclear chromosome segregation
JVX92_RS01290	COG0552	protein localization to endoplasmic reticulum
JVX92_RS01300	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JVX92_RS01305	COG0321	lipoyl(octanoyl) transferase activity
JVX92_RS01325	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JVX92_RS01330	COG0228	four-way junction DNA binding
JVX92_RS01335	COG1837	Belongs to the UPF0109 family
JVX92_RS01340	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JVX92_RS01345	COG0336	Belongs to the RNA methyltransferase TrmD family
JVX92_RS01360	COG0335	large ribosomal subunit rRNA binding
JVX92_RS01370	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JVX92_RS01380	COG0792	nuclease activity
JVX92_RS01410	COG0052	Belongs to the universal ribosomal protein uS2 family
JVX92_RS01415	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JVX92_RS01420	COG0528	UMP kinase activity
JVX92_RS01425	COG0233	cytoplasmic translational termination
JVX92_RS01460	COG3118	belongs to the thioredoxin family
JVX92_RS01465	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JVX92_RS01470	COG0366	Alpha amylase catalytic
JVX92_RS01485	COG0482	sulfurtransferase activity
JVX92_RS01490	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JVX92_RS01495	COG0318	PFAM AMP-dependent synthetase and ligase
JVX92_RS01500	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JVX92_RS01505	COG0154	amidase activity
JVX92_RS01510	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JVX92_RS01515	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JVX92_RS01535	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JVX92_RS01550	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JVX92_RS01600	COG1946	Acyl-CoA thioesterase
JVX92_RS01620	COG0668	transmembrane transport
JVX92_RS01625	COG2197	response regulator
JVX92_RS01630	COG4585	Histidine kinase
JVX92_RS01640	COG1131	(ABC) transporter
JVX92_RS01655	COG0659	secondary active sulfate transmembrane transporter activity
JVX92_RS01665	COG0698	ribose 5-phosphate isomerase
JVX92_RS01685	COG0783	Belongs to the Dps family
JVX92_RS01705	COG0544	peptidyl-prolyl cis-trans isomerase activity
JVX92_RS01710	COG0740	serine-type endopeptidase activity
JVX92_RS01715	COG0740	serine-type endopeptidase activity
JVX92_RS01720	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JVX92_RS01755	COG0525	valine-tRNA ligase activity
JVX92_RS01765	COG0519	Catalyzes the synthesis of GMP from XMP
JVX92_RS01770	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JVX92_RS01775	COG0285	dihydrofolate synthase activity
JVX92_RS01785	COG0105	UTP biosynthetic process
JVX92_RS01795	COG1530	ribonuclease E activity
JVX92_RS01805	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JVX92_RS01810	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JVX92_RS01815	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JVX92_RS01820	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JVX92_RS01825	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JVX92_RS01835	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JVX92_RS01845	COG0799	negative regulation of ribosome biogenesis
JVX92_RS01860	COG1263	PTS System
JVX92_RS01860	COG2190	(PTS) system
JVX92_RS01860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JVX92_RS01880	COG0512	Glutamine amidotransferase of anthranilate synthase
JVX92_RS01880	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JVX92_RS01885	COG0495	leucyl-tRNA aminoacylation
JVX92_RS01890	COG1596	polysaccharide export
JVX92_RS01890	COG1555	photosystem II stabilization
JVX92_RS01905	COG0268	Binds directly to 16S ribosomal RNA
JVX92_RS01920	COG1525	nuclease
JVX92_RS01920	COG4085	toxin activity
JVX92_RS01920	COG0737	Belongs to the 5'-nucleotidase family
JVX92_RS01925	COG0481	GTPase activity
JVX92_RS01940	COG1420	regulation of RNA biosynthetic process
JVX92_RS01945	COG0484	heat shock protein binding
JVX92_RS01955	COG0537	adenosine 5'-monophosphoramidase activity
JVX92_RS01965	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JVX92_RS01975	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JVX92_RS01980	COG1028	Short-chain dehydrogenase reductase Sdr
JVX92_RS01980	COG0604	alcohol dehydrogenase
JVX92_RS01980	COG3321	synthase
JVX92_RS01995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JVX92_RS02000	COG2860	membrane
JVX92_RS02005	COG1381	Involved in DNA repair and RecF pathway recombination
JVX92_RS02010	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JVX92_RS02020	COG0386	Belongs to the glutathione peroxidase family
JVX92_RS02035	COG0358	DNA primase activity
JVX92_RS02075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JVX92_RS02080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JVX92_RS02095	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JVX92_RS02105	COG0531	amino acid
JVX92_RS02150	COG0174	glutamine synthetase
JVX92_RS02155	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JVX92_RS02180	COG0174	glutamine synthetase
JVX92_RS02200	COG0508	dehydrogenase complex catalyzes the overall conversion of
JVX92_RS02205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JVX92_RS02210	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JVX92_RS02220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JVX92_RS02240	COG0187	DNA topoisomerase II activity
JVX92_RS02250	COG2197	response regulator
JVX92_RS02255	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JVX92_RS02280	COG0756	dUTP diphosphatase activity
JVX92_RS02295	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JVX92_RS02300	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JVX92_RS02310	COG1309	transcriptional regulator
JVX92_RS02325	COG0183	Belongs to the thiolase family
JVX92_RS02345	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JVX92_RS02410	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JVX92_RS02425	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
JVX92_RS02435	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JVX92_RS02440	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JVX92_RS02455	COG0217	transcriptional regulatory protein
JVX92_RS02460	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JVX92_RS02465	COG0632	four-way junction helicase activity
JVX92_RS02470	COG2255	four-way junction helicase activity
JVX92_RS02480	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JVX92_RS02485	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JVX92_RS02490	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JVX92_RS02515	COG0494	nUDIX hydrolase
JVX92_RS02525	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JVX92_RS02535	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JVX92_RS02540	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JVX92_RS02545	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JVX92_RS02550	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JVX92_RS02555	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JVX92_RS02560	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JVX92_RS02565	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JVX92_RS02580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JVX92_RS02585	COG1309	transcriptional regulator
JVX92_RS02590	COG1082	Xylose isomerase domain protein TIM barrel
JVX92_RS02590	COG3185	4-Hydroxyphenylpyruvate dioxygenase
JVX92_RS02595	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JVX92_RS02600	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JVX92_RS02605	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JVX92_RS02610	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JVX92_RS02630	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JVX92_RS02635	COG0540	Belongs to the ATCase OTCase family
JVX92_RS02640	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JVX92_RS02650	COG0505	Belongs to the CarA family
JVX92_RS02655	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JVX92_RS02660	COG0284	orotidine-5'-phosphate decarboxylase activity
JVX92_RS02665	COG0194	GDP metabolic process
JVX92_RS02670	COG1758	RNA polymerase activity
JVX92_RS02675	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JVX92_RS02680	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JVX92_RS02685	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JVX92_RS02695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JVX92_RS02700	COG0140	phosphoribosyl-ATP diphosphatase activity
JVX92_RS02705	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JVX92_RS02710	COG0107	imidazoleglycerol-phosphate synthase activity
JVX92_RS02715	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JVX92_RS02730	COG0134	indole-3-glycerol-phosphate synthase activity
JVX92_RS02735	COG0133	tryptophan synthase activity
JVX92_RS02740	COG0159	tryptophan synthase activity
JVX92_RS02745	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JVX92_RS02750	COG0067	glutamate synthase
JVX92_RS02750	COG0070	glutamate synthase
JVX92_RS02750	COG0069	glutamate synthase activity
JVX92_RS02795	COG0477	Major facilitator Superfamily
JVX92_RS02820	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JVX92_RS02835	COG4946	Tricorn protease homolog
JVX92_RS02835	COG1506	peptidase
JVX92_RS02835	COG0823	Involved in the tonB-independent uptake of proteins
JVX92_RS02840	COG1028	Short-chain dehydrogenase reductase Sdr
JVX92_RS02870	COG4581	dead DEAH box helicase
JVX92_RS02875	COG0805	protein transport
JVX92_RS02880	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JVX92_RS02915	COG1968	undecaprenyl-diphosphatase activity
JVX92_RS02920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JVX92_RS02970	COG1960	acyl-CoA dehydrogenase activity
JVX92_RS02980	COG0508	dehydrogenase complex catalyzes the overall conversion of
JVX92_RS02985	COG0022	dehydrogenase e1 component
JVX92_RS03000	COG0697	spore germination
JVX92_RS03020	COG0254	rRNA binding
JVX92_RS03025	COG1119	ATPase activity
JVX92_RS03030	COG0297	glycogen (starch) synthase activity
JVX92_RS03035	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JVX92_RS03040	COG3830	Belongs to the UPF0237 family
JVX92_RS03040	COG0560	Phosphoserine phosphatase
JVX92_RS03050	COG1028	Short-chain dehydrogenase reductase Sdr
JVX92_RS03075	COG0488	(ABC) transporter
JVX92_RS03080	COG1268	BioY protein
JVX92_RS03090	COG1120	ATPase activity
JVX92_RS03095	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX92_RS03100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX92_RS03110	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JVX92_RS03115	COG2151	metal-sulfur cluster biosynthetic enzyme
JVX92_RS03120	COG0396	ATPase activity
JVX92_RS03150	COG0109	protoheme IX farnesyltransferase activity
JVX92_RS03160	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JVX92_RS03165	COG0166	Belongs to the GPI family
JVX92_RS03180	COG0363	glucosamine-6-phosphate deaminase activity
JVX92_RS03190	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JVX92_RS03195	COG0149	triose-phosphate isomerase activity
JVX92_RS03200	COG0126	phosphoglycerate kinase activity
JVX92_RS03205	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JVX92_RS03215	COG1481	regulation of sporulation
JVX92_RS03220	COG1660	Displays ATPase and GTPase activities
JVX92_RS03225	COG0322	excinuclease ABC activity
JVX92_RS03235	COG1846	Transcriptional regulator
JVX92_RS03245	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JVX92_RS03250	COG0556	nucleotide-excision repair
JVX92_RS03260	COG0237	dephospho-CoA kinase activity
JVX92_RS03270	COG5002	protein histidine kinase activity
JVX92_RS03275	COG0539	negative regulation of cytoplasmic translation
JVX92_RS03285	COG3012	SEC-C Motif Domain Protein
JVX92_RS03300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JVX92_RS03305	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JVX92_RS03305	COG1796	DNA polymerase
JVX92_RS03315	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JVX92_RS03320	COG1845	cytochrome c oxidase, subunit III
JVX92_RS03325	COG2010	Cytochrome c
JVX92_RS03330	COG0723	plastoquinol--plastocyanin reductase activity
JVX92_RS03335	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JVX92_RS03355	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JVX92_RS03360	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JVX92_RS03385	COG0167	dihydroorotate dehydrogenase activity
JVX92_RS03390	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JVX92_RS03395	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JVX92_RS03415	COG0318	PFAM AMP-dependent synthetase and ligase
JVX92_RS03425	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JVX92_RS03440	COG1799	cell septum assembly
JVX92_RS03450	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JVX92_RS03460	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JVX92_RS03470	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JVX92_RS03480	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JVX92_RS03485	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JVX92_RS03495	COG0768	penicillin binding
JVX92_RS03505	COG0275	rRNA processing
JVX92_RS03510	COG2001	Belongs to the MraZ family
JVX92_RS03520	COG0142	geranyltranstransferase activity
JVX92_RS03530	COG1388	LysM domain
JVX92_RS03535	COG0515	serine threonine protein kinase
JVX92_RS03535	COG2815	serine threonine protein kinase
JVX92_RS03540	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JVX92_RS03545	COG0204	Acyl-transferase
JVX92_RS03550	COG1940	carbohydrate kinase activity
JVX92_RS03555	COG1022	Amp-dependent synthetase and ligase
JVX92_RS03570	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JVX92_RS03575	COG1192	Involved in chromosome partitioning
JVX92_RS03590	COG1716	ATPase activity
JVX92_RS03605	COG2372	response to copper ion
JVX92_RS03645	COG0058	SHG alpha-glucan phosphorylase activity
JVX92_RS03655	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JVX92_RS03670	COG1012	belongs to the aldehyde dehydrogenase family
JVX92_RS03670	COG1454	alcohol dehydrogenase
JVX92_RS03680	COG1780	Probably involved in ribonucleotide reductase function
JVX92_RS03695	COG0569	domain protein
JVX92_RS03695	COG0475	glutathione-regulated potassium exporter activity
JVX92_RS03715	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JVX92_RS03720	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JVX92_RS03740	COG1309	transcriptional regulator
JVX92_RS03750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JVX92_RS03765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JVX92_RS03775	COG1119	ATPase activity
JVX92_RS03785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JVX92_RS03830	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JVX92_RS03915	COG1160	GTP binding
JVX92_RS03920	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JVX92_RS03935	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JVX92_RS03940	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JVX92_RS03955	COG1104	cysteine desulfurase activity
JVX92_RS03970	COG0494	nUDIX hydrolase
JVX92_RS03975	COG0504	CTP synthase activity
JVX92_RS03980	COG0497	DNA recombination
JVX92_RS03985	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JVX92_RS04015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JVX92_RS04025	COG4214	carbohydrate transport
JVX92_RS04030	COG1129	ABC transporter
JVX92_RS04035	COG1609	Transcriptional regulator
JVX92_RS04045	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JVX92_RS04060	COG0165	Argininosuccinate lyase
JVX92_RS04070	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JVX92_RS04080	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JVX92_RS04085	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JVX92_RS04090	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JVX92_RS04110	COG0072	phenylalanine-tRNA ligase activity
JVX92_RS04110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JVX92_RS04115	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JVX92_RS04120	COG0765	amino acid transport
JVX92_RS04125	COG0765	amino acid transport
JVX92_RS04130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JVX92_RS04135	COG1126	abc transporter atp-binding protein
JVX92_RS04140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JVX92_RS04145	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JVX92_RS04150	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JVX92_RS04155	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JVX92_RS04170	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JVX92_RS04175	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JVX92_RS04180	COG0131	Imidazoleglycerol-phosphate dehydratase
JVX92_RS04185	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JVX92_RS04195	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JVX92_RS04205	COG1501	Belongs to the glycosyl hydrolase 31 family
JVX92_RS04210	COG3387	PFAM Glycoside hydrolase 15-related
JVX92_RS04220	COG0395	ABC-type sugar transport system, permease component
JVX92_RS04225	COG1175	transmembrane transport
JVX92_RS04230	COG1846	Transcriptional regulator
JVX92_RS04230	COG1940	carbohydrate kinase activity
JVX92_RS04235	COG1501	Belongs to the glycosyl hydrolase 31 family
JVX92_RS04240	COG1501	Belongs to the glycosyl hydrolase 31 family
JVX92_RS04250	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JVX92_RS04260	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JVX92_RS04265	COG2813	Specifically methylates the guanine in position
JVX92_RS04270	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JVX92_RS04275	COG0456	acetyltransferase
JVX92_RS04280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JVX92_RS04285	COG2137	regulation of response to DNA damage stimulus
JVX92_RS04290	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JVX92_RS04300	COG1396	sequence-specific DNA binding
JVX92_RS04305	COG1058	Belongs to the CinA family
JVX92_RS04305	COG1546	Belongs to the CinA family
JVX92_RS04315	COG1674	ftsk spoiiie
JVX92_RS04325	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JVX92_RS04330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JVX92_RS04335	COG4221	oxidoreductase activity
JVX92_RS04340	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JVX92_RS04345	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JVX92_RS04390	COG1185	polyribonucleotide nucleotidyltransferase activity
JVX92_RS04400	COG0438	transferase activity, transferring glycosyl groups
JVX92_RS04410	COG1301	dicarboxylic acid transport
JVX92_RS04415	COG3290	protein histidine kinase activity
JVX92_RS04420	COG4565	transcriptional regulatory protein
JVX92_RS04425	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JVX92_RS04430	COG3387	PFAM Glycoside hydrolase 15-related
JVX92_RS04435	COG0431	NADPH-dependent FMN reductase
JVX92_RS04440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX92_RS04445	COG3594	Acyltransferase
JVX92_RS04465	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JVX92_RS04470	COG1872	DUF167
JVX92_RS04480	COG0697	spore germination
JVX92_RS04485	COG2353	YceI-like domain
JVX92_RS04490	COG0545	Peptidyl-prolyl cis-trans isomerase
JVX92_RS04495	COG0179	Fumarylacetoacetate (FAA) hydrolase
JVX92_RS04510	COG0667	Aldo Keto reductase
JVX92_RS04515	COG0789	Transcriptional regulator
JVX92_RS04550	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JVX92_RS04570	COG0196	riboflavin kinase activity
JVX92_RS04585	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JVX92_RS04590	COG1194	a g-specific adenine glycosylase
JVX92_RS04600	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JVX92_RS04605	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JVX92_RS04615	COG0195	Participates in both transcription termination and antitermination
JVX92_RS04635	COG1611	Belongs to the LOG family
JVX92_RS04645	COG0442	prolyl-tRNA aminoacylation
JVX92_RS04660	COG2515	1-aminocyclopropane-1-carboxylate deaminase
JVX92_RS04670	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JVX92_RS04680	COG0750	zinc metalloprotease
JVX92_RS04695	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JVX92_RS04705	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JVX92_RS04710	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JVX92_RS04720	COG0318	PFAM AMP-dependent synthetase and ligase
JVX92_RS04720	COG0204	Acyl-transferase
JVX92_RS04765	COG3022	response to hydroperoxide
JVX92_RS04775	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JVX92_RS04780	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JVX92_RS04785	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JVX92_RS04790	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JVX92_RS04795	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JVX92_RS04800	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JVX92_RS04805	COG0356	it plays a direct role in the translocation of protons across the membrane
JVX92_RS04815	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JVX92_RS04825	COG2890	protein-(glutamine-N5) methyltransferase activity
JVX92_RS04835	COG1045	serine acetyltransferase
JVX92_RS04845	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JVX92_RS04855	COG0083	homoserine kinase activity
JVX92_RS04865	COG0460	homoserine dehydrogenase
JVX92_RS04870	COG0019	diaminopimelate decarboxylase activity
JVX92_RS04880	COG0018	arginyl-trna synthetase
JVX92_RS04885	COG1305	Transglutaminase-like
JVX92_RS04930	COG0765	amino acid transport
JVX92_RS04960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JVX92_RS04970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JVX92_RS04975	COG0601	transmembrane transport
JVX92_RS04985	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JVX92_RS05000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX92_RS05005	COG0626	cystathionine gamma-synthase activity
JVX92_RS05025	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JVX92_RS05035	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JVX92_RS05050	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JVX92_RS05065	COG1842	Phage shock protein A
JVX92_RS05085	COG2365	Tyrosine phosphatase family
JVX92_RS05095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JVX92_RS05095	COG0596	Alpha beta hydrolase
JVX92_RS05105	COG0601	transmembrane transport
JVX92_RS05110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JVX92_RS05115	COG0444	Belongs to the ABC transporter superfamily
JVX92_RS05140	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JVX92_RS05145	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
JVX92_RS05155	COG4221	oxidoreductase activity
JVX92_RS05165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JVX92_RS05170	COG2814	Major facilitator Superfamily
JVX92_RS05175	COG0011	TIGRFAM Protein of
JVX92_RS05190	COG1902	pentaerythritol trinitrate reductase activity
JVX92_RS05200	COG1253	flavin adenine dinucleotide binding
JVX92_RS05220	COG0567	Dehydrogenase, E1 component
JVX92_RS05220	COG0508	dehydrogenase complex catalyzes the overall conversion of
JVX92_RS05250	COG1595	DNA-templated transcription, initiation
JVX92_RS05260	COG1162	GTPase activity
JVX92_RS05285	COG0489	protein tyrosine kinase activity
JVX92_RS05315	COG0653	protein targeting
JVX92_RS05335	COG5401	PFAM Sporulation and spore germination
JVX92_RS05340	COG5000	phosphorelay sensor kinase activity
JVX92_RS05340	COG5002	protein histidine kinase activity
JVX92_RS05345	COG0745	RESPONSE REGULATOR receiver
JVX92_RS05350	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JVX92_RS05355	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
JVX92_RS05365	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JVX92_RS05450	COG0463	Glycosyl transferase, family 2
JVX92_RS05460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JVX92_RS05465	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
JVX92_RS05500	COG1088	dTDP-glucose 4,6-dehydratase activity
JVX92_RS05515	COG0438	transferase activity, transferring glycosyl groups
JVX92_RS05520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JVX92_RS05530	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JVX92_RS05530	COG0546	phosphoglycolate phosphatase activity
JVX92_RS05555	COG0297	glycogen (starch) synthase activity
JVX92_RS05565	COG1316	TRANSCRIPTIONal
JVX92_RS05590	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JVX92_RS05615	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JVX92_RS05620	COG0424	maF-like protein
JVX92_RS05625	COG4770	biotin carboxylase activity
JVX92_RS05645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JVX92_RS05660	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JVX92_RS05665	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JVX92_RS05670	COG2213	PTS system mannitol-specific
JVX92_RS05675	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JVX92_RS05680	COG0246	Mannitol dehydrogenase
JVX92_RS05695	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JVX92_RS05710	COG1079	Belongs to the binding-protein-dependent transport system permease family
JVX92_RS05715	COG4603	Belongs to the binding-protein-dependent transport system permease family
JVX92_RS05720	COG3845	ABC transporter
JVX92_RS05725	COG1744	ABC transporter substrate-binding protein PnrA-like
JVX92_RS05730	COG0662	Cupin 2, conserved barrel domain protein
JVX92_RS05730	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
JVX92_RS05735	COG2009	succinate dehydrogenase
JVX92_RS05765	COG0180	Tryptophanyl-tRNA synthetase
JVX92_RS05780	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JVX92_RS05785	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JVX92_RS05800	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JVX92_RS05800	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JVX92_RS05805	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JVX92_RS05820	COG0477	Major facilitator Superfamily
JVX92_RS05835	COG1131	(ABC) transporter
JVX92_RS05840	COG1132	(ABC) transporter
JVX92_RS05875	COG1595	DNA-templated transcription, initiation
JVX92_RS05890	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
JVX92_RS05905	COG2822	iron ion transport
JVX92_RS05910	COG2837	iron assimilation
JVX92_RS05950	COG1116	anion transmembrane transporter activity
JVX92_RS05970	COG1129	ABC transporter
JVX92_RS05995	COG1028	Short-chain dehydrogenase reductase Sdr
JVX92_RS06030	COG0477	Major facilitator Superfamily
JVX92_RS06035	COG0179	Fumarylacetoacetate (FAA) hydrolase
JVX92_RS06055	COG3971	2-oxopent-4-enoate hydratase activity
JVX92_RS06065	COG1305	Transglutaminase-like
JVX92_RS06090	COG0765	amino acid transport
JVX92_RS06095	COG1126	abc transporter atp-binding protein
JVX92_RS06105	COG0697	spore germination
JVX92_RS06115	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JVX92_RS06120	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JVX92_RS06145	COG0277	FAD linked oxidase domain protein
JVX92_RS06160	COG0395	ABC-type sugar transport system, permease component
JVX92_RS06165	COG1175	transmembrane transport
JVX92_RS06190	COG2838	Isocitrate dehydrogenase
JVX92_RS06210	COG1175	transmembrane transport
JVX92_RS06215	COG0395	ABC-type sugar transport system, permease component
JVX92_RS06220	COG1501	Belongs to the glycosyl hydrolase 31 family
JVX92_RS06230	COG1132	(ABC) transporter
JVX92_RS06240	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JVX92_RS06250	COG3264	Mechanosensitive ion channel
JVX92_RS06250	COG1511	domain protein
JVX92_RS06265	COG0477	Major facilitator Superfamily
JVX92_RS06270	COG0138	bifunctional purine biosynthesis protein purh
JVX92_RS06275	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JVX92_RS06285	COG2252	PERMEase
JVX92_RS06295	COG0045	succinate-CoA ligase (ADP-forming) activity
JVX92_RS06305	COG1309	transcriptional regulator
JVX92_RS06310	COG1960	acyl-CoA dehydrogenase activity
JVX92_RS06315	COG1793	dna ligase
JVX92_RS06370	COG3304	Inner membrane component domain
JVX92_RS06385	COG1404	Belongs to the peptidase S8 family
JVX92_RS06395	COG1131	(ABC) transporter
JVX92_RS06400	COG0584	glycerophosphoryl diester phosphodiesterase
JVX92_RS06410	COG0519	Catalyzes the synthesis of GMP from XMP
JVX92_RS06410	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JVX92_RS06425	COG0516	GMP reductase activity
JVX92_RS06430	COG3548	integral membrane protein
JVX92_RS06435	COG0488	(ABC) transporter
JVX92_RS06480	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JVX92_RS06500	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JVX92_RS06505	COG0456	acetyltransferase
JVX92_RS06515	COG0802	atpase or kinase
JVX92_RS06520	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JVX92_RS06525	COG0736	holo-[acyl-carrier-protein] synthase activity
JVX92_RS06530	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JVX92_RS06535	COG1072	(Pantothenic acid kinase))
JVX92_RS06540	COG0248	Ppx GppA phosphatase
JVX92_RS06545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JVX92_RS06550	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JVX92_RS06555	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JVX92_RS06590	COG2197	response regulator
JVX92_RS06600	COG4585	Histidine kinase
JVX92_RS06635	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JVX92_RS06650	COG1216	Glycosyl transferase, family 2
JVX92_RS06660	COG0438	transferase activity, transferring glycosyl groups
JVX92_RS06695	COG0489	protein tyrosine kinase activity
JVX92_RS06715	COG5002	protein histidine kinase activity
JVX92_RS06740	COG0745	RESPONSE REGULATOR receiver
JVX92_RS06775	COG0101	tRNA pseudouridine synthase activity
JVX92_RS06795	COG0203	ribosomal protein L17
JVX92_RS06800	COG0202	RNA polymerase activity
JVX92_RS06805	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JVX92_RS06810	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JVX92_RS06820	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JVX92_RS06835	COG0024	Methionine aminopeptidase
JVX92_RS06840	COG0563	adenylate kinase activity
JVX92_RS06850	COG0200	Binds to the 23S rRNA
JVX92_RS06855	COG1841	ribosomal large subunit assembly
JVX92_RS06860	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JVX92_RS06865	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JVX92_RS06870	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JVX92_RS06875	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JVX92_RS06880	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JVX92_RS06885	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JVX92_RS06890	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JVX92_RS06895	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JVX92_RS06900	COG0255	Belongs to the universal ribosomal protein uL29 family
JVX92_RS06905	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JVX92_RS06910	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JVX92_RS06915	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JVX92_RS06920	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JVX92_RS06925	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JVX92_RS06930	COG0089	rRNA binding
JVX92_RS06935	COG0088	Forms part of the polypeptide exit tunnel
JVX92_RS06940	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JVX92_RS06945	COG0051	transcription antitermination factor activity, RNA binding
JVX92_RS06955	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JVX92_RS06960	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JVX92_RS06965	COG0049	tRNA binding
JVX92_RS06970	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JVX92_RS06990	COG0714	Associated with various cellular activities
JVX92_RS07035	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JVX92_RS07040	COG0085	RNA polymerase activity
JVX92_RS07045	COG1984	allophanate hydrolase subunit 2
JVX92_RS07050	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JVX92_RS07085	COG0577	efflux transmembrane transporter activity
JVX92_RS07085	COG1136	(ABC) transporter
JVX92_RS07090	COG2197	response regulator
JVX92_RS07095	COG4585	Histidine kinase
JVX92_RS07120	COG0339	signal peptide processing
JVX92_RS07140	COG0488	(ABC) transporter
JVX92_RS07145	COG1201	RNA secondary structure unwinding
JVX92_RS07150	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JVX92_RS07230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JVX92_RS07240	COG0747	negative chemotaxis
JVX92_RS07265	COG1070	Carbohydrate kinase
JVX92_RS07270	COG2115	Belongs to the xylose isomerase family
JVX92_RS07290	COG1175	transmembrane transport
JVX92_RS07295	COG0395	ABC-type sugar transport system, permease component
JVX92_RS07300	COG1472	Belongs to the glycosyl hydrolase 3 family
JVX92_RS07325	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JVX92_RS07345	COG2130	NADP-dependent
JVX92_RS07365	COG2205	protein histidine kinase activity
JVX92_RS07370	COG2050	protein possibly involved in aromatic compounds catabolism
JVX92_RS07375	COG1309	transcriptional regulator
JVX92_RS07380	COG0183	Belongs to the thiolase family
JVX92_RS07385	COG1024	Enoyl-CoA hydratase
JVX92_RS07390	COG1250	3-hydroxyacyl-CoA dehydrogenase
JVX92_RS07395	COG1012	belongs to the aldehyde dehydrogenase family
JVX92_RS07395	COG2030	dehydratase
JVX92_RS07400	COG2050	protein possibly involved in aromatic compounds catabolism
JVX92_RS07405	COG3396	Phenylacetate-CoA oxygenase
JVX92_RS07410	COG3460	Phenylacetate-CoA oxygenase
JVX92_RS07415	COG3396	Phenylacetate-CoA oxygenase
JVX92_RS07420	COG2151	metal-sulfur cluster biosynthetic enzyme
JVX92_RS07425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JVX92_RS07435	COG0667	Aldo Keto reductase
JVX92_RS07440	COG2072	flavoprotein involved in K transport
JVX92_RS07450	COG0765	amino acid transport
JVX92_RS07455	COG0765	amino acid transport
JVX92_RS07460	COG1126	abc transporter atp-binding protein
JVX92_RS07470	COG1028	Short-chain dehydrogenase reductase Sdr
JVX92_RS07475	COG1028	Short-chain dehydrogenase reductase Sdr
JVX92_RS07480	COG0583	DNA-binding transcription factor activity
JVX92_RS07520	COG3979	chitinase
JVX92_RS07620	COG4974	Belongs to the 'phage' integrase family
JVX92_RS07640	COG0039	L-malate dehydrogenase activity
JVX92_RS07645	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JVX92_RS07660	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JVX92_RS07665	COG2308	Evidence 4 Homologs of previously reported genes of
JVX92_RS07665	COG2307	Protein conserved in bacteria
JVX92_RS07675	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JVX92_RS07710	COG1461	Dihydroxyacetone kinase
JVX92_RS07715	COG2376	Dihydroxyacetone kinase
JVX92_RS07725	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JVX92_RS07755	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JVX92_RS07765	COG0302	gtp cyclohydrolase
JVX92_RS07770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JVX92_RS07780	COG0037	tRNA processing
JVX92_RS07785	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JVX92_RS07790	COG0739	heme binding
JVX92_RS07810	COG2226	methyltransferase
JVX92_RS07830	COG2272	Belongs to the type-B carboxylesterase lipase family
JVX92_RS07835	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JVX92_RS07915	COG0463	Glycosyl transferase, family 2
JVX92_RS07935	COG0513	Belongs to the DEAD box helicase family
JVX92_RS07950	COG0039	L-malate dehydrogenase activity
JVX92_RS07955	COG0025	NhaP-type Na H and K H
JVX92_RS07970	COG1674	ftsk spoiiie
JVX92_RS07970	COG0433	COG0433 Predicted ATPase
JVX92_RS07990	COG0631	protein serine/threonine phosphatase activity
JVX92_RS08010	COG0714	Associated with various cellular activities
JVX92_RS08020	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JVX92_RS08025	COG0519	Catalyzes the synthesis of GMP from XMP
JVX92_RS08030	COG3833	ABC-type maltose transport systems, permease component
JVX92_RS08035	COG1175	transmembrane transport
JVX92_RS08040	COG1653	transport
JVX92_RS08055	COG1070	Carbohydrate kinase
JVX92_RS08060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JVX92_RS08065	COG2186	Transcriptional regulator
JVX92_RS08085	COG1309	transcriptional regulator
JVX92_RS08095	COG0514	ATP-dependent DNA helicase (RecQ)
JVX92_RS08100	COG4581	dead DEAH box helicase
JVX92_RS08105	COG1472	Belongs to the glycosyl hydrolase 3 family
JVX92_RS08115	COG1741	Belongs to the pirin family
JVX92_RS08125	COG1122	ATPase activity
JVX92_RS08130	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JVX92_RS08150	COG1960	acyl-CoA dehydrogenase activity
JVX92_RS08155	COG1876	peptidase activity
JVX92_RS08165	COG0513	Belongs to the DEAD box helicase family
JVX92_RS08175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JVX92_RS08180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JVX92_RS08205	COG0789	Transcriptional regulator
JVX92_RS08240	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JVX92_RS08270	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JVX92_RS08275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX92_RS08315	COG0789	Transcriptional regulator
JVX92_RS08325	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JVX92_RS08335	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JVX92_RS08380	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JVX92_RS08395	COG2113	Glycine betaine
JVX92_RS08405	COG3448	diguanylate cyclase activity
JVX92_RS08405	COG4175	Glycine betaine
JVX92_RS08415	COG1131	(ABC) transporter
JVX92_RS08425	COG1605	Chorismate mutase
JVX92_RS08425	COG0287	Prephenate dehydrogenase
JVX92_RS08445	COG1175	transmembrane transport
JVX92_RS08450	COG0395	ABC-type sugar transport system, permease component
JVX92_RS08455	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JVX92_RS08455	COG4447	cellulose binding
JVX92_RS08460	COG1940	carbohydrate kinase activity
JVX92_RS08460	COG1846	Transcriptional regulator
JVX92_RS08470	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JVX92_RS08485	COG1309	transcriptional regulator
JVX92_RS08510	COG1320	monovalent cation:proton antiporter activity
JVX92_RS08515	COG2212	antiporter activity
JVX92_RS08525	COG0651	ATP synthesis coupled electron transport
JVX92_RS08530	COG1006	Multisubunit Na H antiporter MnhC subunit
JVX92_RS08535	COG2111	Na H antiporter
JVX92_RS08535	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JVX92_RS08540	COG1609	Transcriptional regulator
JVX92_RS08545	COG0738	Major facilitator superfamily
JVX92_RS08555	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
JVX92_RS08560	COG0546	phosphoglycolate phosphatase activity
JVX92_RS08565	COG1278	Cold shock
JVX92_RS08575	COG0515	serine threonine protein kinase
JVX92_RS08580	COG4585	Histidine kinase
JVX92_RS08585	COG2197	response regulator
JVX92_RS08595	COG2271	Major facilitator Superfamily
JVX92_RS08600	COG2186	Transcriptional regulator
JVX92_RS08625	COG1716	ATPase activity
JVX92_RS08640	COG0768	penicillin binding
JVX92_RS08645	COG0515	serine threonine protein kinase
JVX92_RS08650	COG0515	serine threonine protein kinase
JVX92_RS08650	COG2815	serine threonine protein kinase
JVX92_RS08660	COG3764	Sortase (surface protein transpeptidase)
JVX92_RS08695	COG0129	dihydroxy-acid dehydratase activity
JVX92_RS08705	COG0577	efflux transmembrane transporter activity
JVX92_RS08710	COG1136	(ABC) transporter
JVX92_RS08710	COG0577	efflux transmembrane transporter activity
JVX92_RS08745	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JVX92_RS08750	COG0187	DNA topoisomerase II activity
JVX92_RS08755	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
JVX92_RS08760	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JVX92_RS08765	COG0592	DNA-directed DNA polymerase activity
JVX92_RS08770	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JVX92_RS08775	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JVX92_RS08780	COG0594	ribonuclease P activity
JVX92_RS08785	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JVX92_RS08790	COG0706	membrane insertase activity
JVX92_RS08800	COG0357	Ribosomal RNA small subunit methyltransferase G
JVX92_RS08805	COG1192	Involved in chromosome partitioning
JVX92_RS08820	COG3118	belongs to the thioredoxin family
JVX92_RS08825	COG0492	ferredoxin-NADP+ reductase activity
JVX92_RS08840	COG2890	protein-(glutamine-N5) methyltransferase activity
JVX92_RS08845	COG0617	tRNA 3'-terminal CCA addition
JVX92_RS08865	COG1846	Transcriptional regulator
JVX92_RS08870	COG1012	belongs to the aldehyde dehydrogenase family
JVX92_RS08890	COG2197	response regulator
JVX92_RS08895	COG4585	Histidine kinase
JVX92_RS08920	COG0601	transmembrane transport
JVX92_RS08930	COG4172	Belongs to the ABC transporter superfamily
JVX92_RS08945	COG0477	Major facilitator Superfamily
JVX92_RS08950	COG0360	Binds together with S18 to 16S ribosomal RNA
JVX92_RS08960	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JVX92_RS08965	COG0359	binds to the 23S rRNA
JVX92_RS08980	COG0305	Participates in initiation and elongation during chromosome replication
JVX92_RS09005	COG1733	regulation of RNA biosynthetic process
JVX92_RS09045	COG2814	Major facilitator Superfamily
JVX92_RS09050	COG1090	epimerase
JVX92_RS09120	COG2182	Extracellular solute-binding protein
JVX92_RS09130	COG0395	ABC-type sugar transport system, permease component
JVX92_RS09135	COG0366	Alpha amylase catalytic
JVX92_RS09170	COG3973	AAA domain
JVX92_RS09175	COG2814	Major facilitator Superfamily
JVX92_RS09190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JVX92_RS09200	COG2354	Protein conserved in bacteria
JVX92_RS09205	COG0534	Mate efflux family protein
JVX92_RS09215	COG0596	Alpha beta hydrolase
JVX92_RS09220	COG0822	iron-sulfur transferase activity
JVX92_RS09230	COG0531	amino acid
JVX92_RS09250	COG1609	Transcriptional regulator
JVX92_RS09255	COG0366	Alpha amylase catalytic
JVX92_RS09260	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JVX92_RS09265	COG1609	Transcriptional regulator
JVX92_RS09275	COG1175	transmembrane transport
JVX92_RS09280	COG0395	ABC-type sugar transport system, permease component
JVX92_RS09300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JVX92_RS09320	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JVX92_RS09335	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JVX92_RS09350	COG0402	S-adenosylhomocysteine deaminase activity
JVX92_RS09355	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JVX92_RS09355	COG2080	2 iron, 2 sulfur cluster binding
JVX92_RS09370	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JVX92_RS09380	COG1116	anion transmembrane transporter activity
JVX92_RS09390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JVX92_RS09395	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JVX92_RS09405	COG0047	phosphoribosylformylglycinamidine synthase activity
JVX92_RS09410	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JVX92_RS09430	COG2723	6-phospho-beta-galactosidase activity
JVX92_RS09440	COG2233	PERMEase
JVX92_RS09465	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JVX92_RS09485	COG0151	Belongs to the GarS family
JVX92_RS09530	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JVX92_RS09535	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JVX92_RS09550	COG1950	PFAM Membrane protein of
JVX92_RS09555	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JVX92_RS09565	COG0022	dehydrogenase e1 component
JVX92_RS09570	COG0508	dehydrogenase complex catalyzes the overall conversion of
JVX92_RS09575	COG2095	MarC family integral membrane protein
JVX92_RS09585	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JVX92_RS09605	COG0477	Major facilitator Superfamily
JVX92_RS09630	COG1121	(ABC) transporter
JVX92_RS09645	COG0701	Predicted permease
JVX92_RS09660	COG2094	Belongs to the DNA glycosylase MPG family
JVX92_RS09665	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JVX92_RS09670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JVX92_RS09675	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JVX92_RS09680	COG0776	regulation of translation
JVX92_RS09695	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JVX92_RS09700	COG5398	heme oxygenase
JVX92_RS09710	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JVX92_RS09755	COG0717	Belongs to the dCTP deaminase family
JVX92_RS09795	COG0443	Heat shock 70 kDa protein
JVX92_RS09800	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JVX92_RS09805	COG0484	heat shock protein binding
JVX92_RS09810	COG0789	Transcriptional regulator
JVX92_RS09820	COG2909	trisaccharide binding
JVX92_RS09820	COG2909	trisaccharide binding
JVX92_RS09835	COG0659	secondary active sulfate transmembrane transporter activity
JVX92_RS09840	COG2015	COG2015, Alkyl sulfatase and related hydrolases
JVX92_RS09845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JVX92_RS09850	COG3537	Alpha-1,2-mannosidase
JVX92_RS09860	COG0438	transferase activity, transferring glycosyl groups
JVX92_RS09870	COG0366	Alpha amylase catalytic
JVX92_RS09870	COG1874	Beta-galactosidase
JVX92_RS09875	COG0366	Alpha amylase catalytic
JVX92_RS09890	COG0395	ABC-type sugar transport system, permease component
JVX92_RS09900	COG1609	Transcriptional regulator
JVX92_RS09935	COG0542	response to heat
JVX92_RS09955	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JVX92_RS09970	COG1668	transmembrane transport
JVX92_RS09975	COG4152	abc transporter atp-binding protein
JVX92_RS09985	COG2197	response regulator
JVX92_RS09990	COG4585	Histidine kinase
JVX92_RS10010	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
JVX92_RS10015	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
JVX92_RS10020	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JVX92_RS10040	COG0477	Major facilitator Superfamily
JVX92_RS10045	COG1609	Transcriptional regulator
JVX92_RS10075	COG0534	Mate efflux family protein
JVX92_RS10085	COG3590	peptidase
JVX92_RS10105	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JVX92_RS10110	COG3104	oligopeptide transport
JVX92_RS10130	COG1846	Transcriptional regulator
JVX92_RS10135	COG1764	response to oxidative stress
JVX92_RS10140	COG4948	Mandelate Racemase Muconate Lactonizing
JVX92_RS10150	COG2268	Band 7 protein
JVX92_RS10160	COG0477	Major facilitator Superfamily
JVX92_RS10165	COG0423	glycine-tRNA ligase activity
JVX92_RS10220	COG3458	cephalosporin-C deacetylase activity
JVX92_RS10240	COG1024	Enoyl-CoA hydratase
JVX92_RS10255	COG0484	heat shock protein binding
JVX92_RS10260	COG0471	metal ion transport
JVX92_RS10260	COG3273	potassium ion transport
JVX92_RS10270	COG4721	ABC-type cobalt transport system, permease component
JVX92_RS10275	COG4172	Belongs to the ABC transporter superfamily
JVX92_RS10280	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JVX92_RS10290	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JVX92_RS10295	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JVX92_RS10300	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JVX92_RS10330	COG1028	Short-chain dehydrogenase reductase Sdr
JVX92_RS10335	COG0561	phosphatase activity
JVX92_RS10340	COG1280	lysine exporter protein (LysE YggA)
JVX92_RS10355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JVX92_RS10355	COG2190	(PTS) system
JVX92_RS10355	COG1263	PTS System
JVX92_RS10360	COG3711	transcriptional antiterminator
JVX92_RS10365	COG4166	transmembrane transport
JVX92_RS10380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JVX92_RS10395	COG4172	Belongs to the ABC transporter superfamily
JVX92_RS10410	COG1175	transmembrane transport
JVX92_RS10425	COG1621	beta-fructofuranosidase activity
JVX92_RS10430	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JVX92_RS10435	COG0667	Aldo Keto reductase
JVX92_RS10450	COG0328	RNA-DNA hybrid ribonuclease activity
JVX92_RS10470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JVX92_RS10490	COG1131	(ABC) transporter
JVX92_RS10495	COG0531	amino acid
JVX92_RS10505	COG0686	Belongs to the AlaDH PNT family
JVX92_RS10510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JVX92_RS10520	COG0076	glutamate decarboxylase activity
JVX92_RS10525	COG0154	amidase activity
JVX92_RS10530	COG2957	Belongs to the agmatine deiminase family
JVX92_RS10545	COG1012	belongs to the aldehyde dehydrogenase family
JVX92_RS10550	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JVX92_RS10570	COG2079	MmgE PrpD family protein
JVX92_RS10575	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JVX92_RS10585	COG0183	Belongs to the thiolase family
JVX92_RS10595	COG1024	Enoyl-CoA hydratase
JVX92_RS10605	COG2086	electron transfer activity
JVX92_RS10610	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JVX92_RS10635	COG1012	belongs to the aldehyde dehydrogenase family
JVX92_RS10645	COG1834	amidinotransferase
JVX92_RS10650	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JVX92_RS10670	COG1305	Transglutaminase-like
JVX92_RS10675	COG1136	(ABC) transporter
JVX92_RS10675	COG0577	efflux transmembrane transporter activity
JVX92_RS10680	COG1136	(ABC) transporter
JVX92_RS10685	COG4585	Histidine kinase
JVX92_RS10690	COG2197	response regulator
JVX92_RS10695	COG0477	Major facilitator Superfamily
JVX92_RS10705	COG2514	catechol 2,3-dioxygenase activity
JVX92_RS10710	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JVX92_RS10740	COG0574	Belongs to the PEP-utilizing enzyme family
JVX92_RS10740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JVX92_RS10745	COG0574	Belongs to the PEP-utilizing enzyme family
JVX92_RS10745	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JVX92_RS10760	COG0039	L-malate dehydrogenase activity
JVX92_RS10765	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
JVX92_RS10775	COG1454	alcohol dehydrogenase
JVX92_RS10775	COG1012	belongs to the aldehyde dehydrogenase family
JVX92_RS10795	COG0546	phosphoglycolate phosphatase activity
JVX92_RS10805	COG2030	dehydratase
JVX92_RS10815	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JVX92_RS10860	COG1070	Carbohydrate kinase
JVX92_RS10865	COG1028	Short-chain dehydrogenase reductase Sdr
JVX92_RS10865	COG3347	Dehydrogenase
JVX92_RS10875	COG1609	Transcriptional regulator
JVX92_RS10885	COG1850	ribulose-bisphosphate carboxylase activity
JVX92_RS10900	COG3250	beta-galactosidase activity
JVX92_RS10910	COG0395	ABC-type sugar transport system, permease component
JVX92_RS10915	COG1175	transmembrane transport
JVX92_RS10925	COG1609	Transcriptional regulator
JVX92_RS10940	COG1028	Short-chain dehydrogenase reductase Sdr
JVX92_RS10945	COG2084	Dehydrogenase
JVX92_RS10950	COG1082	Xylose isomerase domain protein TIM barrel
JVX92_RS10955	COG0149	triose-phosphate isomerase activity
JVX92_RS10960	COG0698	ribose 5-phosphate isomerase
JVX92_RS10965	COG2376	Dihydroxyacetone kinase
JVX92_RS10985	COG3250	beta-galactosidase activity
JVX92_RS11005	COG0444	Belongs to the ABC transporter superfamily
JVX92_RS11025	COG3250	beta-galactosidase activity
JVX92_RS11055	COG2267	carboxylic ester hydrolase activity
JVX92_RS11060	COG0095	Lipoate-protein ligase
JVX92_RS11065	COG2189	Belongs to the N(4) N(6)-methyltransferase family
JVX92_RS11080	COG1472	Belongs to the glycosyl hydrolase 3 family
JVX92_RS11090	COG2267	carboxylic ester hydrolase activity
JVX92_RS11095	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JVX92_RS11105	COG1609	Transcriptional regulator
JVX92_RS11115	COG1609	Transcriptional regulator
JVX92_RS11125	COG0395	ABC-type sugar transport system, permease component
JVX92_RS11140	COG3534	alpha-L-arabinofuranosidase
JVX92_RS11150	COG1929	Belongs to the glycerate kinase type-1 family
JVX92_RS11170	COG0077	Prephenate dehydratase
JVX92_RS11175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX92_RS11180	COG0415	Belongs to the DNA photolyase family
JVX92_RS11190	COG3226	Transcriptional regulator
JVX92_RS11200	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JVX92_RS11205	COG0561	phosphatase activity
JVX92_RS11215	COG1316	TRANSCRIPTIONal
JVX92_RS11225	COG0454	-acetyltransferase
JVX92_RS11230	COG0384	phenazine biosynthesis protein PhzF
JVX92_RS11315	COG0395	ABC-type sugar transport system, permease component
JVX92_RS11340	COG2873	o-acetylhomoserine
JVX92_RS11360	COG2357	RelA SpoT domain protein
JVX92_RS11380	COG0477	Major facilitator Superfamily
JVX92_RS11395	COG2017	converts alpha-aldose to the beta-anomer
JVX92_RS11450	COG1472	Belongs to the glycosyl hydrolase 3 family
JVX92_RS11455	COG1472	Belongs to the glycosyl hydrolase 3 family
JVX92_RS11465	COG1215	transferase activity, transferring glycosyl groups
JVX92_RS11470	COG3279	Response regulator of the LytR AlgR family
JVX92_RS11485	COG1760	l-serine dehydratase
JVX92_RS11505	COG1131	(ABC) transporter
JVX92_RS11585	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JVX92_RS11620	COG1136	(ABC) transporter
JVX92_RS11630	COG0492	ferredoxin-NADP+ reductase activity
JVX92_RS11640	COG0166	Belongs to the GPI family
JVX92_RS11650	COG2197	response regulator
JVX92_RS11710	COG0745	RESPONSE REGULATOR receiver
JVX92_RS11760	COG1609	Transcriptional regulator
JVX92_RS11795	COG2160	L-arabinose isomerase activity
JVX92_RS11805	COG0477	Major facilitator Superfamily
JVX92_RS11815	COG0419	ATPase involved in DNA repair
JVX92_RS11845	COG0598	Magnesium transport protein CorA
JVX92_RS11850	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JVX92_RS11860	COG0596	Alpha beta hydrolase
JVX92_RS11860	COG0508	dehydrogenase complex catalyzes the overall conversion of
JVX92_RS11875	COG0747	negative chemotaxis
JVX92_RS11890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JVX92_RS11910	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JVX92_RS11920	COG0569	domain protein
JVX92_RS11925	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JVX92_RS11930	COG0640	Transcriptional regulator
JVX92_RS11955	COG3422	double-strand break repair
JVX92_RS11965	COG0017	Asparaginyl-tRNA synthetase
JVX92_RS11970	COG0586	Pfam SNARE associated Golgi protein
JVX92_RS11975	COG0406	alpha-ribazole phosphatase activity
JVX92_RS11985	COG0785	Cytochrome C biogenesis protein
JVX92_RS11990	COG1333	cytochrome c biogenesis protein
JVX92_RS11995	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JVX92_RS12005	COG2409	Drug exporters of the RND superfamily
JVX92_RS12010	COG1309	transcriptional regulator
JVX92_RS12015	COG4948	Mandelate Racemase Muconate Lactonizing
JVX92_RS12020	COG1410	methionine synthase
JVX92_RS12020	COG0646	methionine synthase
JVX92_RS12050	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JVX92_RS12075	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JVX92_RS12080	COG2326	polyphosphate kinase activity
JVX92_RS12085	COG1169	isochorismate synthase
JVX92_RS12095	COG2226	methyltransferase
JVX92_RS12100	COG0142	geranyltranstransferase activity
JVX92_RS12130	COG1666	GTP binding
JVX92_RS12155	COG0483	inositol monophosphate 1-phosphatase activity
JVX92_RS12180	COG0656	L-ascorbic acid biosynthetic process
JVX92_RS12185	COG0667	Aldo Keto reductase
JVX92_RS12210	COG0730	response to heat
JVX92_RS12215	COG2030	dehydratase
JVX92_RS12225	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JVX92_RS12235	COG0436	Aminotransferase
JVX92_RS12245	COG2271	Major facilitator Superfamily
JVX92_RS12250	COG0800	Aldolase
JVX92_RS12255	COG1349	DNA-binding transcription factor activity
JVX92_RS12285	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JVX92_RS12305	COG1175	transmembrane transport
JVX92_RS12310	COG0395	ABC-type sugar transport system, permease component
JVX92_RS12325	COG2871	sodium ion transport
JVX92_RS12345	COG0745	RESPONSE REGULATOR receiver
JVX92_RS12380	COG1012	belongs to the aldehyde dehydrogenase family
JVX92_RS12390	COG0326	Molecular chaperone. Has ATPase activity
JVX92_RS12405	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JVX92_RS12415	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JVX92_RS12420	COG0081	regulation of translation
JVX92_RS12425	COG1254	Belongs to the acylphosphatase family
JVX92_RS12440	COG3321	synthase
JVX92_RS12440	COG0604	alcohol dehydrogenase
JVX92_RS12460	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JVX92_RS12465	COG0222	ribosome binding
JVX92_RS12475	COG1653	transport
JVX92_RS12480	COG1175	transmembrane transport
JVX92_RS12485	COG0395	ABC-type sugar transport system, permease component
JVX92_RS12490	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JVX92_RS12510	COG2814	Major facilitator Superfamily
JVX92_RS12520	COG0433	COG0433 Predicted ATPase
JVX92_RS12525	COG0702	epimerase
JVX92_RS12535	COG0521	Mo-molybdopterin cofactor biosynthetic process
JVX92_RS12540	COG0314	molybdopterin synthase activity
JVX92_RS12550	COG0315	cyclic pyranopterin monophosphate synthase activity
JVX92_RS12565	COG3585	molybdate ion transport
JVX92_RS12595	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JVX92_RS12600	COG1132	(ABC) transporter
JVX92_RS12605	COG4988	ABC transporter
JVX92_RS12610	COG1294	oxidase, subunit
JVX92_RS12615	COG1271	oxidase subunit
JVX92_RS12630	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JVX92_RS12640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX92_RS12645	COG3507	Belongs to the glycosyl hydrolase 43 family
JVX92_RS12670	COG2873	o-acetylhomoserine
JVX92_RS12695	COG1125	glycine betaine transport
JVX92_RS12695	COG0517	IMP dehydrogenase activity
JVX92_RS12705	COG0702	epimerase
JVX92_RS12710	COG1733	regulation of RNA biosynthetic process
JVX92_RS12730	COG1362	aminopeptidase activity
JVX92_RS12770	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JVX92_RS12780	COG0494	nUDIX hydrolase
JVX92_RS12810	COG1823	symporter activity
JVX92_RS12825	COG0714	Associated with various cellular activities
JVX92_RS12840	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JVX92_RS12890	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JVX92_RS12890	COG0352	thiamine-phosphate diphosphorylase activity
JVX92_RS12890	COG0351	phosphomethylpyrimidine kinase
JVX92_RS12895	COG0352	thiamine-phosphate diphosphorylase activity
JVX92_RS12900	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JVX92_RS12905	COG2072	flavoprotein involved in K transport
JVX92_RS12915	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JVX92_RS12925	COG0515	serine threonine protein kinase
JVX92_RS12925	COG2815	serine threonine protein kinase
JVX92_RS12955	COG5297	Belongs to the glycosyl hydrolase family 6
JVX92_RS12955	COG3250	beta-galactosidase activity
JVX92_RS12975	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JVX92_RS12995	COG0579	oxidoreductase
JVX92_RS13000	COG1435	thymidine kinase activity
JVX92_RS13030	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JVX92_RS13055	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JVX92_RS13085	COG1754	DNA topoisomerase type I activity
JVX92_RS13085	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JVX92_RS13090	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JVX92_RS13095	COG0470	DNA polymerase III
JVX92_RS13105	COG2011	ABC-type metal ion transport system permease component
JVX92_RS13110	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JVX92_RS13130	COG2409	Drug exporters of the RND superfamily
JVX92_RS13135	COG1335	isochorismatase
JVX92_RS13160	COG1595	DNA-templated transcription, initiation
JVX92_RS13185	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JVX92_RS13190	COG0581	inorganic phosphate transmembrane transporter activity
JVX92_RS13230	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JVX92_RS13235	COG0745	RESPONSE REGULATOR receiver
JVX92_RS13245	COG4044	May play a role in the intracellular transport of hydrophobic ligands
JVX92_RS13265	COG0588	phosphoglycerate mutase activity
JVX92_RS13280	COG0745	RESPONSE REGULATOR receiver
JVX92_RS13290	COG1329	Transcriptional regulator
JVX92_RS13295	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JVX92_RS13295	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JVX92_RS13300	COG0454	-acetyltransferase
JVX92_RS13305	COG0215	cysteine-tRNA ligase activity
JVX92_RS13310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JVX92_RS13315	COG2910	NAD(P)H-binding
JVX92_RS13325	COG3842	ATPase activity
JVX92_RS13355	COG1321	iron dependent repressor
JVX92_RS13375	COG0583	DNA-binding transcription factor activity
JVX92_RS13380	COG2159	amidohydrolase
JVX92_RS13405	COG0667	Aldo Keto reductase
JVX92_RS13415	COG0673	inositol 2-dehydrogenase activity
JVX92_RS13420	COG1053	succinate dehydrogenase
JVX92_RS13435	COG1028	Short-chain dehydrogenase reductase Sdr
JVX92_RS13440	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JVX92_RS13445	COG0477	Major facilitator Superfamily
JVX92_RS13450	COG0583	DNA-binding transcription factor activity
JVX92_RS13460	COG1053	succinate dehydrogenase
JVX92_RS13470	COG1053	succinate dehydrogenase
JVX92_RS13485	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JVX92_RS13510	COG0459	protein refolding
JVX92_RS13520	COG2205	protein histidine kinase activity
JVX92_RS13525	COG0745	RESPONSE REGULATOR receiver
JVX92_RS13535	COG1061	Type III restriction enzyme res subunit
JVX92_RS13550	COG1278	Cold shock
JVX92_RS13560	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JVX92_RS13620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JVX92_RS13630	COG0402	S-adenosylhomocysteine deaminase activity
JVX92_RS13640	COG0402	S-adenosylhomocysteine deaminase activity
JVX92_RS13650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JVX92_RS13655	COG0587	DNA-directed DNA polymerase activity
JVX92_RS13660	COG3527	Alpha-acetolactate decarboxylase
JVX92_RS13665	COG0028	Belongs to the TPP enzyme family
JVX92_RS13670	COG0583	DNA-binding transcription factor activity
JVX92_RS13675	COG0028	Belongs to the TPP enzyme family
JVX92_RS13695	COG2755	lipolytic protein G-D-S-L family
JVX92_RS13695	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JVX92_RS13720	COG0300	oxidoreductase activity
JVX92_RS13735	COG2837	iron assimilation
JVX92_RS13740	COG2140	Oxalate decarboxylase
JVX92_RS13770	COG3903	Transcriptional regulator
JVX92_RS13770	COG3629	intracellular signal transduction
JVX92_RS13780	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JVX92_RS13780	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JVX92_RS13800	COG1609	Transcriptional regulator
JVX92_RS13810	COG3250	beta-galactosidase activity
JVX92_RS13820	COG4209	transmembrane transport
JVX92_RS13825	COG0395	ABC-type sugar transport system, permease component
JVX92_RS13835	COG3408	Glycogen debranching enzyme
JVX92_RS13840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JVX92_RS13855	COG1278	Cold shock
JVX92_RS13885	COG1228	amidohydrolase
JVX92_RS13890	COG2272	Belongs to the type-B carboxylesterase lipase family
JVX92_RS13905	COG2197	response regulator
JVX92_RS13920	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JVX92_RS13950	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JVX92_RS13985	COG2963	transposase activity
JVX92_RS13990	COG2801	Transposase and inactivated derivatives
JVX92_RS14025	COG1902	pentaerythritol trinitrate reductase activity
JVX92_RS14030	COG1309	transcriptional regulator
JVX92_RS14090	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JVX92_RS14095	COG0543	2 iron, 2 sulfur cluster binding
JVX92_RS14095	COG0633	Ferredoxin
JVX92_RS14105	COG0318	PFAM AMP-dependent synthetase and ligase
JVX92_RS14130	COG0395	ABC-type sugar transport system, permease component
JVX92_RS14145	COG1609	Transcriptional regulator
JVX92_RS14155	COG2986	histidine ammonia-lyase
JVX92_RS14160	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JVX92_RS14165	COG1228	amidohydrolase
JVX92_RS14185	COG2733	membrane
JVX92_RS14190	COG1937	Protein conserved in bacteria
JVX92_RS14220	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JVX92_RS14225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JVX92_RS14240	COG2813	Specifically methylates the guanine in position
JVX92_RS14255	COG4565	transcriptional regulatory protein
JVX92_RS14260	COG3290	protein histidine kinase activity
JVX92_RS14265	COG2851	Citrate transporter
JVX92_RS14280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JVX92_RS14335	COG3833	ABC-type maltose transport systems, permease component
JVX92_RS14340	COG1175	transmembrane transport
JVX92_RS14345	COG2182	Extracellular solute-binding protein
JVX92_RS14355	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JVX92_RS14360	COG0084	hydrolase, TatD family'
JVX92_RS14380	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JVX92_RS14385	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JVX92_RS14395	COG3253	May function as heme-dependent peroxidase
JVX92_RS14400	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JVX92_RS14415	COG0113	porphobilinogen synthase activity
JVX92_RS14420	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JVX92_RS14430	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JVX92_RS14445	COG0667	Aldo Keto reductase
JVX92_RS14450	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JVX92_RS14455	COG4552	Acetyltransferase involved in intracellular survival and related
JVX92_RS14460	COG0488	(ABC) transporter
JVX92_RS14470	COG0446	pyridine nucleotide-disulphide oxidoreductase
JVX92_RS14480	COG1937	Protein conserved in bacteria
JVX92_RS14490	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JVX92_RS14495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JVX92_RS14515	COG1017	nitric oxide dioxygenase activity
JVX92_RS14515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JVX92_RS14520	COG2205	protein histidine kinase activity
JVX92_RS14525	COG0745	RESPONSE REGULATOR receiver
JVX92_RS14535	COG0577	efflux transmembrane transporter activity
JVX92_RS14535	COG1136	(ABC) transporter
JVX92_RS14540	COG0598	Magnesium transport protein CorA
JVX92_RS14545	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JVX92_RS14550	COG2084	Dehydrogenase
JVX92_RS14565	COG0477	Major facilitator Superfamily
JVX92_RS14575	COG2186	Transcriptional regulator
JVX92_RS14580	COG2610	gluconate transmembrane transporter activity
JVX92_RS14585	COG1028	Short-chain dehydrogenase reductase Sdr
JVX92_RS14590	COG1063	alcohol dehydrogenase
JVX92_RS14595	COG3265	gluconokinase activity
JVX92_RS14605	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JVX92_RS14610	COG0193	aminoacyl-tRNA hydrolase activity
JVX92_RS14630	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JVX92_RS14640	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JVX92_RS14645	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JVX92_RS14655	COG0124	histidyl-tRNA synthetase
JVX92_RS14665	COG0477	Major facilitator Superfamily
JVX92_RS14670	COG2755	lipolytic protein G-D-S-L family
JVX92_RS14675	COG1725	Transcriptional regulator
JVX92_RS14685	COG4122	O-methyltransferase activity
JVX92_RS14690	COG0148	phosphopyruvate hydratase activity
JVX92_RS14735	COG1704	LemA family
JVX92_RS14740	COG0501	Belongs to the peptidase M48B family
JVX92_RS14750	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JVX92_RS14760	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JVX92_RS14780	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JVX92_RS14790	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JVX92_RS14795	COG0745	RESPONSE REGULATOR receiver
JVX92_RS14800	COG2205	protein histidine kinase activity
JVX92_RS14805	COG0114	fumarate hydratase activity
JVX92_RS14820	COG1722	exodeoxyribonuclease VII activity
JVX92_RS14825	COG1570	exodeoxyribonuclease VII activity
JVX92_RS14830	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JVX92_RS14840	COG2258	MOSC domain
JVX92_RS14845	COG0191	fructose-bisphosphate aldolase activity
JVX92_RS14850	COG1494	fructose-1,6-bisphosphatase
JVX92_RS14860	COG1322	Protein conserved in bacteria
JVX92_RS14880	COG0012	GTP binding
JVX92_RS14885	COG0477	Major facilitator Superfamily
JVX92_RS14965	COG1028	Short-chain dehydrogenase reductase Sdr
JVX92_RS15015	COG0489	protein tyrosine kinase activity
JVX92_RS15035	COG1475	DNA binding