locus-tag	class	description
GRX76_RS00100	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GRX76_RS00105	COG0739	heme binding
GRX76_RS00110	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GRX76_RS00115	COG0316	Belongs to the HesB IscA family
GRX76_RS00130	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GRX76_RS00145	COG0351	phosphomethylpyrimidine kinase
GRX76_RS00150	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GRX76_RS00155	COG3135	benzoate transporter
GRX76_RS00170	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GRX76_RS00185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GRX76_RS00190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GRX76_RS00195	COG5001	Diguanylate cyclase
GRX76_RS00195	COG5002	protein histidine kinase activity
GRX76_RS00225	COG0511	ligase activity, forming carbon-carbon bonds
GRX76_RS00235	COG2264	protein methyltransferase activity
GRX76_RS00250	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GRX76_RS00260	COG0138	bifunctional purine biosynthesis protein purh
GRX76_RS00265	COG0151	Belongs to the GarS family
GRX76_RS00270	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
GRX76_RS00275	COG1765	OsmC-like protein
GRX76_RS00290	COG0339	signal peptide processing
GRX76_RS00295	COG0583	DNA-binding transcription factor activity
GRX76_RS00305	COG0134	indole-3-glycerol-phosphate synthase activity
GRX76_RS00310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GRX76_RS00315	COG0512	Glutamine amidotransferase of anthranilate synthase
GRX76_RS00330	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GRX76_RS00335	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GRX76_RS00340	COG3178	'Phosphotransferase
GRX76_RS00345	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GRX76_RS00350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GRX76_RS00355	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GRX76_RS00360	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GRX76_RS00365	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GRX76_RS00375	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GRX76_RS00380	COG2766	serine protein kinase
GRX76_RS00385	COG2718	Belongs to the UPF0229 family
GRX76_RS00390	COG2719	SpoVR family
GRX76_RS00425	COG0745	RESPONSE REGULATOR receiver
GRX76_RS00430	COG2972	Histidine kinase
GRX76_RS00440	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GRX76_RS00445	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GRX76_RS00450	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GRX76_RS00455	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GRX76_RS00460	COG1610	YqeY-like protein
GRX76_RS00465	COG0358	DNA primase activity
GRX76_RS00470	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GRX76_RS00490	COG0582	viral genome integration into host DNA
GRX76_RS00520	COG2814	Major facilitator Superfamily
GRX76_RS00530	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GRX76_RS00545	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GRX76_RS00550	COG1070	Carbohydrate kinase
GRX76_RS00555	COG2115	Belongs to the xylose isomerase family
GRX76_RS00565	COG2211	Major facilitator Superfamily
GRX76_RS00615	COG0673	inositol 2-dehydrogenase activity
GRX76_RS00620	COG2814	Major facilitator Superfamily
GRX76_RS00640	COG1609	Transcriptional regulator
GRX76_RS00655	COG1012	belongs to the aldehyde dehydrogenase family
GRX76_RS00665	COG0129	dihydroxy-acid dehydratase activity
GRX76_RS00690	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GRX76_RS00730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GRX76_RS00790	COG3866	Pectate lyase
GRX76_RS00805	COG3866	Pectate lyase
GRX76_RS00825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GRX76_RS00830	COG2186	Transcriptional regulator
GRX76_RS00835	COG0246	Mannitol dehydrogenase
GRX76_RS00840	COG1312	Catalyzes the dehydration of D-mannonate
GRX76_RS00850	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GRX76_RS00865	COG1028	Short-chain dehydrogenase reductase Sdr
GRX76_RS00885	COG1904	glucuronate isomerase
GRX76_RS00890	COG0246	Mannitol dehydrogenase
GRX76_RS00895	COG3005	denitrification pathway
GRX76_RS00900	COG3043	anaerobic respiration
GRX76_RS00905	COG0243	molybdopterin cofactor binding
GRX76_RS00910	COG3062	negative regulation of establishment of protein localization
GRX76_RS00915	COG4459	periplasmic nitrate reductase
GRX76_RS00930	COG1028	Short-chain dehydrogenase reductase Sdr
GRX76_RS00935	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GRX76_RS00940	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GRX76_RS00945	COG4771	TonB-dependent receptor
GRX76_RS00955	COG2186	Transcriptional regulator
GRX76_RS00960	COG2721	sulfolactate sulfo-lyase activity
GRX76_RS00985	COG3264	Mechanosensitive ion channel
GRX76_RS00985	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GRX76_RS01000	COG1012	belongs to the aldehyde dehydrogenase family
GRX76_RS01020	COG2808	Putative FMN-binding domain
GRX76_RS01040	COG0110	maltose O-acetyltransferase activity
GRX76_RS01045	COG4977	sequence-specific DNA binding
GRX76_RS01060	COG0346	lactoylglutathione lyase activity
GRX76_RS01075	COG0308	aminopeptidase N
GRX76_RS01085	COG0457	Tetratricopeptide repeat
GRX76_RS01090	COG4771	TonB-dependent receptor
GRX76_RS01120	COG3275	phosphorelay sensor kinase activity
GRX76_RS01130	COG0436	Aminotransferase
GRX76_RS01150	COG1960	acyl-CoA dehydrogenase activity
GRX76_RS01175	COG0305	Participates in initiation and elongation during chromosome replication
GRX76_RS01180	COG0359	binds to the 23S rRNA
GRX76_RS01190	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GRX76_RS01195	COG0360	Binds together with S18 to 16S ribosomal RNA
GRX76_RS01240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GRX76_RS01245	COG0557	exoribonuclease II activity
GRX76_RS01255	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GRX76_RS01275	COG0515	serine threonine protein kinase
GRX76_RS01275	COG2815	serine threonine protein kinase
GRX76_RS01285	COG3501	Rhs element vgr protein
GRX76_RS01410	COG2814	Major facilitator Superfamily
GRX76_RS01420	COG2951	lytic endotransglycosylase activity
GRX76_RS01425	COG1272	protein, Hemolysin III
GRX76_RS01430	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GRX76_RS01435	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GRX76_RS01440	COG0330	HflC and HflK could
GRX76_RS01445	COG0330	HflC and HflK could
GRX76_RS01450	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GRX76_RS01455	COG1923	regulation of RNA biosynthetic process
GRX76_RS01465	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GRX76_RS01470	COG0860	N-Acetylmuramoyl-L-alanine amidase
GRX76_RS01475	COG0802	atpase or kinase
GRX76_RS01480	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GRX76_RS01480	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GRX76_RS01490	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GRX76_RS01495	COG1162	GTPase activity
GRX76_RS01505	COG0688	phosphatidylethanolamine metabolic process
GRX76_RS01515	COG2199	diguanylate cyclase activity
GRX76_RS01515	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GRX76_RS01520	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GRX76_RS01535	COG1757	Na H antiporter
GRX76_RS01540	COG0493	'glutamate synthase
GRX76_RS01545	COG0070	glutamate synthase
GRX76_RS01545	COG0069	glutamate synthase activity
GRX76_RS01545	COG0067	glutamate synthase
GRX76_RS01550	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GRX76_RS01555	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GRX76_RS01600	COG0840	transmembrane signaling receptor activity
GRX76_RS01630	COG1678	Uncharacterized ACR, COG1678
GRX76_RS01635	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GRX76_RS01735	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GRX76_RS01740	COG0724	RNA recognition motif
GRX76_RS01755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GRX76_RS01770	COG2813	Specifically methylates the guanine in position
GRX76_RS01770	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GRX76_RS01775	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GRX76_RS01815	COG1028	Short-chain dehydrogenase reductase Sdr
GRX76_RS01830	COG2972	Histidine kinase
GRX76_RS01830	COG0745	RESPONSE REGULATOR receiver
GRX76_RS01835	COG0165	Argininosuccinate lyase
GRX76_RS01845	COG1965	Belongs to the frataxin family
GRX76_RS01860	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GRX76_RS01880	COG0347	Belongs to the P(II) protein family
GRX76_RS01885	COG0004	ammonium transporteR
GRX76_RS01890	COG0347	Belongs to the P(II) protein family
GRX76_RS01905	COG0606	chelatase, subunit chli
GRX76_RS01925	COG1671	Belongs to the UPF0178 family
GRX76_RS01935	COG0659	secondary active sulfate transmembrane transporter activity
GRX76_RS01945	COG0210	DNA helicase
GRX76_RS02005	COG2130	NADP-dependent
GRX76_RS02025	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GRX76_RS02030	COG2010	Cytochrome c
GRX76_RS02035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GRX76_RS02055	COG2304	oxidoreductase activity
GRX76_RS02080	COG1741	Belongs to the pirin family
GRX76_RS02090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GRX76_RS02095	COG1028	Short-chain dehydrogenase reductase Sdr
GRX76_RS02115	COG2268	Band 7 protein
GRX76_RS02140	COG2186	Transcriptional regulator
GRX76_RS02165	COG2271	Major facilitator Superfamily
GRX76_RS02170	COG1028	Short-chain dehydrogenase reductase Sdr
GRX76_RS02175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GRX76_RS02190	COG0456	acetyltransferase
GRX76_RS02235	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GRX76_RS02265	COG1121	(ABC) transporter
GRX76_RS02270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GRX76_RS02290	COG0109	protoheme IX farnesyltransferase activity
GRX76_RS02295	COG1612	heme a metabolic process
GRX76_RS02325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GRX76_RS02330	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GRX76_RS02335	COG0534	Mate efflux family protein
GRX76_RS02355	COG0339	signal peptide processing
GRX76_RS02360	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GRX76_RS02370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GRX76_RS02375	COG4774	siderophore transport
GRX76_RS02380	COG0531	amino acid
GRX76_RS02400	COG2235	arginine
GRX76_RS02415	COG0583	DNA-binding transcription factor activity
GRX76_RS02425	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GRX76_RS02430	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GRX76_RS02435	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GRX76_RS02445	COG0408	coproporphyrinogen oxidase activity
GRX76_RS02450	COG0009	L-threonylcarbamoyladenylate synthase
GRX76_RS02460	COG0758	DNA mediated transformation
GRX76_RS02465	COG1652	LysM domain
GRX76_RS02470	COG0242	peptide deformylase activity
GRX76_RS02485	COG0569	domain protein
GRX76_RS02490	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GRX76_RS02495	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GRX76_RS02505	COG0752	glycyl-tRNA synthetase alpha subunit
GRX76_RS02510	COG0751	glycine-tRNA ligase activity
GRX76_RS02520	COG1404	Belongs to the peptidase S8 family
GRX76_RS02525	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GRX76_RS02560	COG0592	DNA-directed DNA polymerase activity
GRX76_RS02565	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GRX76_RS02570	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GRX76_RS02575	COG0594	ribonuclease P activity
GRX76_RS02580	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GRX76_RS02585	COG0706	membrane insertase activity
GRX76_RS02590	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GRX76_RS02595	COG0445	tRNA wobble uridine modification
GRX76_RS02600	COG0357	Ribosomal RNA small subunit methyltransferase G
GRX76_RS02605	COG1192	Involved in chromosome partitioning
GRX76_RS02610	COG1475	DNA binding
GRX76_RS02620	COG0356	it plays a direct role in the translocation of protons across the membrane
GRX76_RS02630	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GRX76_RS02635	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GRX76_RS02640	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GRX76_RS02645	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GRX76_RS02650	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GRX76_RS02655	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GRX76_RS02670	COG1752	Esterase of the alpha-beta hydrolase superfamily
GRX76_RS02680	COG0402	S-adenosylhomocysteine deaminase activity
GRX76_RS02695	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GRX76_RS02715	COG1349	DNA-binding transcription factor activity
GRX76_RS02720	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GRX76_RS02745	COG4771	TonB-dependent receptor
GRX76_RS02750	COG3040	lipid binding
GRX76_RS02775	COG0457	Tetratricopeptide repeat
GRX76_RS02790	COG1741	Belongs to the pirin family
GRX76_RS02805	COG2259	Doxx family
GRX76_RS02810	COG0435	Glutathione S-transferase
GRX76_RS02825	COG0625	glutathione transferase activity
GRX76_RS02830	COG2814	Major facilitator Superfamily
GRX76_RS02840	COG1737	Transcriptional regulator
GRX76_RS02845	COG0210	DNA helicase
GRX76_RS02850	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GRX76_RS02860	COG1607	acyl-coa hydrolase
GRX76_RS02875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GRX76_RS02880	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GRX76_RS02885	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GRX76_RS02900	COG0573	inorganic phosphate transmembrane transporter activity
GRX76_RS02910	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GRX76_RS02915	COG0704	Plays a role in the regulation of phosphate uptake
GRX76_RS02935	COG3022	response to hydroperoxide
GRX76_RS02965	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GRX76_RS02970	COG3161	chorismate lyase activity
GRX76_RS02975	COG1301	dicarboxylic acid transport
GRX76_RS02990	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GRX76_RS02995	COG0583	DNA-binding transcription factor activity
GRX76_RS03000	COG2261	transglycosylase associated protein
GRX76_RS03015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GRX76_RS03020	COG1758	RNA polymerase activity
GRX76_RS03025	COG0194	GDP metabolic process
GRX76_RS03035	COG1064	alcohol dehydrogenase
GRX76_RS03040	COG1404	Belongs to the peptidase S8 family
GRX76_RS03050	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GRX76_RS03055	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GRX76_RS03065	COG1561	YicC-like family, N-terminal region
GRX76_RS03070	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GRX76_RS03080	COG0708	Exodeoxyribonuclease III
GRX76_RS03085	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GRX76_RS03095	COG1309	transcriptional regulator
GRX76_RS03100	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GRX76_RS03110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GRX76_RS03115	COG2003	Belongs to the UPF0758 family
GRX76_RS03120	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GRX76_RS03125	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GRX76_RS03130	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GRX76_RS03165	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GRX76_RS03170	COG0742	ribosomal rna small subunit methyltransferase
GRX76_RS03175	COG0552	protein localization to endoplasmic reticulum
GRX76_RS03180	COG2884	Cell division ATP-binding protein ftsE
GRX76_RS03185	COG2177	Part of the ABC transporter FtsEX involved in
GRX76_RS03195	COG2363	Small membrane protein
GRX76_RS03200	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GRX76_RS03210	COG0488	(ABC) transporter
GRX76_RS03235	COG1346	cytolysis
GRX76_RS03245	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GRX76_RS03250	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GRX76_RS03255	COG2918	glutathione biosynthetic process
GRX76_RS03265	COG0281	malic enzyme
GRX76_RS03280	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GRX76_RS03295	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GRX76_RS03300	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GRX76_RS03315	COG1785	Belongs to the alkaline phosphatase family
GRX76_RS03335	COG2226	methyltransferase
GRX76_RS03345	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GRX76_RS03350	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GRX76_RS03355	COG0140	phosphoribosyl-ATP diphosphatase activity
GRX76_RS03365	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GRX76_RS03390	COG1490	D-aminoacyl-tRNA deacylase activity
GRX76_RS03395	COG1505	serine-type exopeptidase activity
GRX76_RS03400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GRX76_RS03405	COG0668	transmembrane transport
GRX76_RS03415	COG2326	polyphosphate kinase activity
GRX76_RS03430	COG3706	GGDEF domain
GRX76_RS03435	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GRX76_RS03485	COG0745	RESPONSE REGULATOR receiver
GRX76_RS03505	COG4771	TonB-dependent receptor
GRX76_RS03530	COG0301	tRNA thio-modification
GRX76_RS03530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GRX76_RS03535	COG0174	glutamine synthetase
GRX76_RS03545	COG3852	Histidine kinase
GRX76_RS03555	COG2824	Alkylphosphonate utilization operon protein PhnA
GRX76_RS03590	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GRX76_RS03595	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GRX76_RS03610	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GRX76_RS03615	COG1011	Hydrolase
GRX76_RS03630	COG1218	3'(2'),5'-bisphosphate nucleotidase
GRX76_RS03665	COG0714	Associated with various cellular activities
GRX76_RS03705	COG2197	response regulator
GRX76_RS03710	COG2197	response regulator
GRX76_RS03760	COG1477	protein flavinylation
GRX76_RS03795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GRX76_RS03815	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GRX76_RS03820	COG4774	siderophore transport
GRX76_RS03855	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GRX76_RS03880	COG0131	Imidazoleglycerol-phosphate dehydratase
GRX76_RS03885	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GRX76_RS03890	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GRX76_RS03895	COG0107	imidazoleglycerol-phosphate synthase activity
GRX76_RS03905	COG0793	Belongs to the peptidase S41A family
GRX76_RS03910	COG4942	peptidase
GRX76_RS03915	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GRX76_RS03930	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GRX76_RS04020	COG1028	Short-chain dehydrogenase reductase Sdr
GRX76_RS04040	COG0560	Phosphoserine phosphatase
GRX76_RS04050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GRX76_RS04085	COG1509	lysine 2,3-aminomutase activity
GRX76_RS04090	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GRX76_RS04095	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GRX76_RS04105	COG1045	serine acetyltransferase
GRX76_RS04110	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GRX76_RS04135	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GRX76_RS04140	COG0156	8-amino-7-oxononanoate synthase activity
GRX76_RS04145	COG2267	carboxylic ester hydrolase activity
GRX76_RS04145	COG2226	methyltransferase
GRX76_RS04155	COG3214	Protein conserved in bacteria
GRX76_RS04165	COG0010	Belongs to the arginase family
GRX76_RS04180	COG1166	arginine decarboxylase activity
GRX76_RS04190	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GRX76_RS04195	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GRX76_RS04215	COG0427	acetyl-CoA hydrolase
GRX76_RS04230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GRX76_RS04235	COG0589	response to stress
GRX76_RS04280	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GRX76_RS04285	COG0784	Response regulator, receiver
GRX76_RS04285	COG2198	Histidine kinase
GRX76_RS04285	COG5002	protein histidine kinase activity
GRX76_RS04310	COG1024	Enoyl-CoA hydratase
GRX76_RS04315	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GRX76_RS04320	COG1960	acyl-CoA dehydrogenase activity
GRX76_RS04325	COG0789	Transcriptional regulator
GRX76_RS04330	COG1595	DNA-templated transcription, initiation
GRX76_RS04345	COG2986	histidine ammonia-lyase
GRX76_RS04355	COG2188	Transcriptional regulator
GRX76_RS04360	COG1228	amidohydrolase
GRX76_RS04365	COG0010	Belongs to the arginase family
GRX76_RS04385	COG2977	Belongs to the P-Pant transferase superfamily
GRX76_RS04390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GRX76_RS04390	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GRX76_RS04400	COG1454	alcohol dehydrogenase
GRX76_RS04405	COG0824	Thioesterase
GRX76_RS04410	COG3384	dioxygenase
GRX76_RS04415	COG1785	Belongs to the alkaline phosphatase family
GRX76_RS04425	COG0745	RESPONSE REGULATOR receiver
GRX76_RS04430	COG0564	pseudouridine synthase activity
GRX76_RS04460	COG3734	2-keto-3-deoxy-galactonokinase
GRX76_RS04465	COG0800	Aldolase
GRX76_RS04470	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GRX76_RS04475	COG3119	arylsulfatase activity
GRX76_RS04485	COG2183	response to ionizing radiation
GRX76_RS04500	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GRX76_RS04510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GRX76_RS04520	COG2885	chlorophyll binding
GRX76_RS04520	COG3047	cAMP biosynthetic process
GRX76_RS04525	COG1297	OPT oligopeptide transporter protein
GRX76_RS04530	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GRX76_RS04535	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GRX76_RS04540	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GRX76_RS04545	COG0640	Transcriptional regulator
GRX76_RS04550	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GRX76_RS04555	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GRX76_RS04575	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GRX76_RS04600	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GRX76_RS04605	COG0730	response to heat
GRX76_RS04630	COG0109	protoheme IX farnesyltransferase activity
GRX76_RS04670	COG0612	Peptidase, M16
GRX76_RS04685	COG0126	phosphoglycerate kinase activity
GRX76_RS04700	COG2962	Rard protein
GRX76_RS04705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GRX76_RS04715	COG0179	Fumarylacetoacetate (FAA) hydrolase
GRX76_RS04720	COG0456	acetyltransferase
GRX76_RS04720	COG1214	PFAM Peptidase M22, glycoprotease
GRX76_RS04740	COG1012	belongs to the aldehyde dehydrogenase family
GRX76_RS04755	COG0861	Integral membrane protein TerC family
GRX76_RS04840	COG1278	Cold shock
GRX76_RS04845	COG0488	(ABC) transporter
GRX76_RS04875	COG1132	(ABC) transporter
GRX76_RS04890	COG4941	Belongs to the sigma-70 factor family
GRX76_RS04895	COG3795	YCII-related domain
GRX76_RS04915	COG0625	glutathione transferase activity
GRX76_RS04925	COG1228	amidohydrolase
GRX76_RS04930	COG4771	TonB-dependent receptor
GRX76_RS04945	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GRX76_RS04950	COG1794	racemase activity, acting on amino acids and derivatives
GRX76_RS04965	COG0513	Belongs to the DEAD box helicase family
GRX76_RS04990	COG1714	RDD family
GRX76_RS05000	COG1064	alcohol dehydrogenase
GRX76_RS05085	COG1012	belongs to the aldehyde dehydrogenase family
GRX76_RS05105	COG4628	conserved protein (DUF2132)
GRX76_RS05125	COG0515	serine threonine protein kinase
GRX76_RS05125	COG2815	serine threonine protein kinase
GRX76_RS05130	COG3046	protein related to deoxyribodipyrimidine photolyase
GRX76_RS05135	COG0415	Belongs to the DNA photolyase family
GRX76_RS05140	COG1960	acyl-CoA dehydrogenase activity
GRX76_RS05170	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GRX76_RS05175	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GRX76_RS05180	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GRX76_RS05205	COG0006	proline dipeptidase activity
GRX76_RS05210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GRX76_RS05215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GRX76_RS05220	COG0705	Rhomboid family
GRX76_RS05225	COG1253	flavin adenine dinucleotide binding
GRX76_RS05245	COG0471	metal ion transport
GRX76_RS05245	COG3273	potassium ion transport
GRX76_RS05250	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GRX76_RS05255	COG0509	glycine decarboxylation via glycine cleavage system
GRX76_RS05260	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
GRX76_RS05265	COG0494	nUDIX hydrolase
GRX76_RS05280	COG3108	Peptidase M15
GRX76_RS05290	COG2989	Protein conserved in bacteria
GRX76_RS05305	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GRX76_RS05310	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GRX76_RS05325	COG0811	peptide transport
GRX76_RS05335	COG0848	biopolymer transport protein
GRX76_RS05340	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GRX76_RS05350	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GRX76_RS05355	COG0129	dihydroxy-acid dehydratase activity
GRX76_RS05360	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GRX76_RS05360	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GRX76_RS05380	COG0006	proline dipeptidase activity
GRX76_RS05390	COG0306	phosphate transporter
GRX76_RS05395	COG1392	Phosphate transport regulator
GRX76_RS05400	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GRX76_RS05410	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GRX76_RS05445	COG0297	glycogen (starch) synthase activity
GRX76_RS05450	COG1519	Transferase
GRX76_RS05460	COG0463	Glycosyl transferase, family 2
GRX76_RS05480	COG1538	Outer membrane efflux protein
GRX76_RS05485	COG2995	paraquat-inducible protein a
GRX76_RS05490	COG2995	paraquat-inducible protein a
GRX76_RS05495	COG3008	intermembrane lipid transfer
GRX76_RS05510	COG0494	nUDIX hydrolase
GRX76_RS05515	COG3151	Protein conserved in bacteria
GRX76_RS05520	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GRX76_RS05530	COG3150	esterase
GRX76_RS05560	COG0513	Belongs to the DEAD box helicase family
GRX76_RS05575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GRX76_RS05580	COG0385	Bile acid
GRX76_RS05590	COG0513	Belongs to the DEAD box helicase family
GRX76_RS05600	COG1473	amidohydrolase
GRX76_RS05610	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GRX76_RS05615	COG3047	cAMP biosynthetic process
GRX76_RS05630	COG0829	nickel cation binding
GRX76_RS05635	COG0831	urea catabolic process
GRX76_RS05640	COG0832	Belongs to the urease beta subunit family
GRX76_RS05645	COG0804	urea catabolic process
GRX76_RS05650	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GRX76_RS05655	COG0830	nickel cation binding
GRX76_RS05660	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GRX76_RS05675	COG2070	2-Nitropropane dioxygenase
GRX76_RS05680	COG0625	glutathione transferase activity
GRX76_RS05685	COG0745	RESPONSE REGULATOR receiver
GRX76_RS05690	COG2205	protein histidine kinase activity
GRX76_RS05690	COG0784	Response regulator, receiver
GRX76_RS05690	COG2198	Histidine kinase
GRX76_RS05690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GRX76_RS05705	COG0559	Belongs to the binding-protein-dependent transport system permease family
GRX76_RS05735	COG3940	Belongs to the glycosyl hydrolase 43 family
GRX76_RS05740	COG2211	Major facilitator Superfamily
GRX76_RS05745	COG2186	Transcriptional regulator
GRX76_RS05770	COG2017	converts alpha-aldose to the beta-anomer
GRX76_RS05775	COG1879	ABC-type sugar transport system periplasmic component
GRX76_RS05780	COG1129	ABC transporter
GRX76_RS05785	COG1172	Belongs to the binding-protein-dependent transport system permease family
GRX76_RS05790	COG1172	Belongs to the binding-protein-dependent transport system permease family
GRX76_RS05805	COG3507	Belongs to the glycosyl hydrolase 43 family
GRX76_RS05810	COG3940	Belongs to the glycosyl hydrolase 43 family
GRX76_RS05830	COG3706	GGDEF domain
GRX76_RS05850	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GRX76_RS05855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GRX76_RS05855	COG2205	protein histidine kinase activity
GRX76_RS05860	COG3507	Belongs to the glycosyl hydrolase 43 family
GRX76_RS05880	COG0488	(ABC) transporter
GRX76_RS05885	COG1024	Enoyl-CoA hydratase
GRX76_RS05895	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GRX76_RS05920	COG3721	Heme iron utilization protein
GRX76_RS05935	COG0811	peptide transport
GRX76_RS05940	COG0848	biopolymer transport protein
GRX76_RS05950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GRX76_RS05955	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GRX76_RS05960	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GRX76_RS05965	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GRX76_RS05970	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GRX76_RS05975	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GRX76_RS05975	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GRX76_RS05990	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GRX76_RS05995	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GRX76_RS06005	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GRX76_RS06015	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GRX76_RS06025	COG1162	GTPase activity
GRX76_RS06035	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GRX76_RS06040	COG0142	geranyltranstransferase activity
GRX76_RS06070	COG1181	Belongs to the D-alanine--D-alanine ligase family
GRX76_RS06075	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
GRX76_RS06080	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GRX76_RS06090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GRX76_RS06100	COG2815	serine threonine protein kinase
GRX76_RS06100	COG0515	serine threonine protein kinase
GRX76_RS06105	COG0515	serine threonine protein kinase
GRX76_RS06105	COG2815	serine threonine protein kinase
GRX76_RS06115	COG1846	Transcriptional regulator
GRX76_RS06125	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GRX76_RS06130	COG1917	Cupin 2, conserved barrel domain protein
GRX76_RS06135	COG0527	aspartate kinase activity
GRX76_RS06145	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GRX76_RS06155	COG3038	cytochrome b561
GRX76_RS06195	COG2365	Tyrosine phosphatase family
GRX76_RS06210	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GRX76_RS06245	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GRX76_RS06260	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GRX76_RS06265	COG0251	oxidation-reduction process
GRX76_RS06270	COG4145	pantothenate transmembrane transporter activity
GRX76_RS06315	COG2197	response regulator
GRX76_RS06335	COG1294	oxidase, subunit
GRX76_RS06340	COG1271	oxidase subunit
GRX76_RS06365	COG2076	Multidrug Resistance protein
GRX76_RS06400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GRX76_RS06420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GRX76_RS06430	COG2076	Multidrug Resistance protein
GRX76_RS06435	COG0557	exoribonuclease II activity
GRX76_RS06440	COG1278	Cold shock
GRX76_RS06450	COG2130	NADP-dependent
GRX76_RS06455	COG1902	pentaerythritol trinitrate reductase activity
GRX76_RS06470	COG0300	oxidoreductase activity
GRX76_RS06485	COG0702	epimerase
GRX76_RS06490	COG1073	alpha beta
GRX76_RS06495	COG1073	alpha beta
GRX76_RS06500	COG0583	DNA-binding transcription factor activity
GRX76_RS06515	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GRX76_RS06520	COG0733	neurotransmitter:sodium symporter activity
GRX76_RS06525	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GRX76_RS06530	COG0733	neurotransmitter:sodium symporter activity
GRX76_RS06535	COG2867	negative regulation of translational initiation
GRX76_RS06545	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GRX76_RS06560	COG0497	DNA recombination
GRX76_RS06570	COG0443	Heat shock 70 kDa protein
GRX76_RS06575	COG0484	heat shock protein binding
GRX76_RS06585	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GRX76_RS06590	COG4067	protein conserved in archaea
GRX76_RS06590	COG0189	ligase activity
GRX76_RS06600	COG0505	Belongs to the CarA family
GRX76_RS06605	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GRX76_RS06635	COG1462	curli production assembly transport component CsgG
GRX76_RS06650	COG2197	response regulator
GRX76_RS06655	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GRX76_RS06690	COG1131	(ABC) transporter
GRX76_RS06695	COG0842	Transport permease protein
GRX76_RS06710	COG0584	glycerophosphoryl diester phosphodiesterase
GRX76_RS06715	COG0584	glycerophosphoryl diester phosphodiesterase
GRX76_RS06735	COG0842	Transport permease protein
GRX76_RS06740	COG1131	(ABC) transporter
GRX76_RS06745	COG0412	Dienelactone hydrolase
GRX76_RS06750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GRX76_RS06755	COG2329	Antibiotic biosynthesis monooxygenase
GRX76_RS06760	COG0303	'Molybdopterin
GRX76_RS06765	COG0243	molybdopterin cofactor binding
GRX76_RS06770	COG2146	nitrite reductase [NAD(P)H] activity
GRX76_RS06775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GRX76_RS06775	COG2146	nitrite reductase [NAD(P)H] activity
GRX76_RS06780	COG2815	serine threonine protein kinase
GRX76_RS06780	COG0515	serine threonine protein kinase
GRX76_RS06785	COG2223	nitrite transmembrane transporter activity
GRX76_RS06790	COG1116	anion transmembrane transporter activity
GRX76_RS06790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GRX76_RS06795	COG3707	response regulator
GRX76_RS06805	COG0746	molybdenum cofactor guanylyltransferase activity
GRX76_RS06815	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GRX76_RS06820	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GRX76_RS06830	COG2755	lipolytic protein G-D-S-L family
GRX76_RS06840	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GRX76_RS06845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GRX76_RS06850	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GRX76_RS06855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GRX76_RS06860	COG0149	triose-phosphate isomerase activity
GRX76_RS06875	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GRX76_RS06905	COG0217	transcriptional regulatory protein
GRX76_RS06915	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GRX76_RS06930	COG0402	S-adenosylhomocysteine deaminase activity
GRX76_RS06935	COG2252	PERMEase
GRX76_RS06950	COG2351	hydroxyisourate hydrolase activity
GRX76_RS06970	COG3257	ureidoglycine aminohydrolase activity
GRX76_RS06980	COG3960	tartronate-semialdehyde synthase activity
GRX76_RS06985	COG3622	Belongs to the hyi family
GRX76_RS06990	COG2084	Dehydrogenase
GRX76_RS07000	COG0469	pyruvate kinase activity
GRX76_RS07015	COG0521	Mo-molybdopterin cofactor biosynthetic process
GRX76_RS07020	COG0315	cyclic pyranopterin monophosphate synthase activity
GRX76_RS07025	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GRX76_RS07060	COG0811	peptide transport
GRX76_RS07090	COG0604	alcohol dehydrogenase
GRX76_RS07115	COG0779	Required for maturation of 30S ribosomal subunits
GRX76_RS07120	COG0195	Participates in both transcription termination and antitermination
GRX76_RS07125	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GRX76_RS07130	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GRX76_RS07135	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GRX76_RS07140	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GRX76_RS07145	COG1185	polyribonucleotide nucleotidyltransferase activity
GRX76_RS07150	COG0730	response to heat
GRX76_RS07155	COG3104	oligopeptide transport
GRX76_RS07175	COG2095	MarC family integral membrane protein
GRX76_RS07185	COG4206	TonB-dependent receptor
GRX76_RS07200	COG1595	DNA-templated transcription, initiation
GRX76_RS07205	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GRX76_RS07210	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GRX76_RS07215	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GRX76_RS07225	COG3100	YcgL domain-containing protein
GRX76_RS07230	COG2983	Belongs to the UPF0260 family
GRX76_RS07245	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GRX76_RS07255	COG0442	prolyl-tRNA aminoacylation
GRX76_RS07270	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GRX76_RS07280	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GRX76_RS07285	COG0632	four-way junction helicase activity
GRX76_RS07290	COG2255	four-way junction helicase activity
GRX76_RS07295	COG0824	Thioesterase
GRX76_RS07315	COG0823	Involved in the tonB-independent uptake of proteins
GRX76_RS07320	COG2885	chlorophyll binding
GRX76_RS07330	COG0602	queuosine metabolic process
GRX76_RS07335	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GRX76_RS07350	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GRX76_RS07355	COG4783	chaperone-mediated protein folding
GRX76_RS07390	COG0508	dehydrogenase complex catalyzes the overall conversion of
GRX76_RS07420	COG2204	response regulator
GRX76_RS07425	COG0577	efflux transmembrane transporter activity
GRX76_RS07430	COG0577	efflux transmembrane transporter activity
GRX76_RS07430	COG1136	(ABC) transporter
GRX76_RS07435	COG1136	(ABC) transporter
GRX76_RS07440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GRX76_RS07445	COG0659	secondary active sulfate transmembrane transporter activity
GRX76_RS07450	COG0589	response to stress
GRX76_RS07460	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GRX76_RS07470	COG0667	Aldo Keto reductase
GRX76_RS07480	COG1560	Kdo2-lipid A biosynthetic process
GRX76_RS07485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GRX76_RS07495	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GRX76_RS07500	COG0676	glucose-6-phosphate 1-epimerase activity
GRX76_RS07515	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GRX76_RS07520	COG1428	Deoxynucleoside kinase
GRX76_RS07540	COG3852	Histidine kinase
GRX76_RS07545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GRX76_RS07550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GRX76_RS07555	COG1489	DNA binding
GRX76_RS07570	COG0501	Belongs to the peptidase M48B family
GRX76_RS07615	COG2818	Glycosylase
GRX76_RS07630	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GRX76_RS07640	COG1012	belongs to the aldehyde dehydrogenase family
GRX76_RS07650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GRX76_RS07735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GRX76_RS07750	COG0174	glutamine synthetase
GRX76_RS07755	COG0205	6-phosphofructokinase activity
GRX76_RS07760	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GRX76_RS07785	COG3028	Belongs to the UPF0307 family
GRX76_RS07790	COG2239	Acts as a magnesium transporter
GRX76_RS07795	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GRX76_RS07800	COG1660	Displays ATPase and GTPase activities
GRX76_RS07820	COG1137	ATPase activity
GRX76_RS07825	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GRX76_RS07835	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GRX76_RS07850	COG0271	Belongs to the BolA IbaG family
GRX76_RS07855	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GRX76_RS07860	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GRX76_RS07870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GRX76_RS07875	COG2046	Belongs to the sulfate adenylyltransferase family
GRX76_RS07885	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GRX76_RS07890	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GRX76_RS07895	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GRX76_RS07900	COG0723	plastoquinol--plastocyanin reductase activity
GRX76_RS07905	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GRX76_RS07910	COG0625	glutathione transferase activity
GRX76_RS07915	COG2969	positive regulation of protein catabolic process
GRX76_RS07925	COG0501	Belongs to the peptidase M48B family
GRX76_RS07930	COG1704	LemA family
GRX76_RS07940	COG2823	Periplasmic or secreted lipoprotein
GRX76_RS07945	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GRX76_RS07950	COG0792	nuclease activity
GRX76_RS07955	COG3107	peptidoglycan biosynthetic process
GRX76_RS07970	COG0175	sulfate reduction
GRX76_RS07975	COG2001	Belongs to the MraZ family
GRX76_RS07980	COG0275	rRNA processing
GRX76_RS07995	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GRX76_RS08000	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GRX76_RS08005	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GRX76_RS08015	COG0772	Belongs to the SEDS family
GRX76_RS08020	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GRX76_RS08025	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GRX76_RS08030	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GRX76_RS08040	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GRX76_RS08045	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GRX76_RS08050	COG0739	heme binding
GRX76_RS08055	COG0653	protein targeting
GRX76_RS08065	COG0494	nUDIX hydrolase
GRX76_RS08100	COG3447	MASE1 domain protein
GRX76_RS08100	COG5002	protein histidine kinase activity
GRX76_RS08100	COG5001	Diguanylate cyclase
GRX76_RS08105	COG3447	MASE1 domain protein
GRX76_RS08105	COG5001	Diguanylate cyclase
GRX76_RS08105	COG5002	protein histidine kinase activity
GRX76_RS08130	COG0822	iron-sulfur transferase activity
GRX76_RS08140	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GRX76_RS08160	COG0105	UTP biosynthetic process
GRX76_RS08165	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GRX76_RS08180	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GRX76_RS08185	COG0124	histidyl-tRNA synthetase
GRX76_RS08190	COG2976	Protein conserved in bacteria
GRX76_RS08200	COG1160	GTP binding
GRX76_RS08210	COG1720	tRNA m6t6A37 methyltransferase activity
GRX76_RS08215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GRX76_RS08225	COG0237	dephospho-CoA kinase activity
GRX76_RS08230	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GRX76_RS08295	COG0110	maltose O-acetyltransferase activity
GRX76_RS08315	COG0463	Glycosyl transferase, family 2
GRX76_RS08320	COG2244	polysaccharide biosynthetic process
GRX76_RS08350	COG0489	protein tyrosine kinase activity
GRX76_RS08365	COG1596	polysaccharide export
GRX76_RS08370	COG2771	luxR family
GRX76_RS08395	COG3267	Type II secretory pathway component ExeA
GRX76_RS08395	COG3409	Peptidoglycan-binding domain 1 protein
GRX76_RS08400	COG0583	DNA-binding transcription factor activity
GRX76_RS08405	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GRX76_RS08410	COG1760	l-serine dehydratase
GRX76_RS08415	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GRX76_RS08420	COG0509	glycine decarboxylation via glycine cleavage system
GRX76_RS08430	COG0435	Glutathione S-transferase
GRX76_RS08435	COG2259	Doxx family
GRX76_RS08440	COG0583	DNA-binding transcription factor activity
GRX76_RS08450	COG0348	domain, Protein
GRX76_RS08455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GRX76_RS08490	COG2738	Putative neutral zinc metallopeptidase
GRX76_RS08500	COG0791	NLP P60 protein
GRX76_RS08520	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GRX76_RS08530	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GRX76_RS08535	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GRX76_RS08535	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GRX76_RS08545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GRX76_RS08550	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GRX76_RS08565	COG2906	2 iron, 2 sulfur cluster binding
GRX76_RS08570	COG0450	alkyl hydroperoxide reductase
GRX76_RS08580	COG0326	Molecular chaperone. Has ATPase activity
GRX76_RS08590	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GRX76_RS08605	COG2062	phosphohistidine phosphatase, SixA
GRX76_RS08620	COG0302	gtp cyclohydrolase
GRX76_RS08625	COG2890	protein-(glutamine-N5) methyltransferase activity
GRX76_RS08630	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GRX76_RS08645	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GRX76_RS08650	COG0066	3-isopropylmalate dehydratase activity
GRX76_RS08655	COG0473	3-isopropylmalate dehydrogenase activity
GRX76_RS08680	COG0135	phosphoribosylanthranilate isomerase activity
GRX76_RS08685	COG0133	tryptophan synthase activity
GRX76_RS08690	COG0159	tryptophan synthase activity
GRX76_RS08695	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GRX76_RS08700	COG0285	dihydrofolate synthase activity
GRX76_RS08710	COG1286	toxin biosynthetic process
GRX76_RS08725	COG0714	Associated with various cellular activities
GRX76_RS08755	COG0366	Alpha amylase catalytic
GRX76_RS08760	COG1215	transferase activity, transferring glycosyl groups
GRX76_RS08765	COG3769	mannosylglycerate metabolic process
GRX76_RS08770	COG0616	signal peptide processing
GRX76_RS08785	COG1393	Belongs to the ArsC family
GRX76_RS08790	COG1295	ribonuclease BN
GRX76_RS08795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GRX76_RS08815	COG0745	RESPONSE REGULATOR receiver
GRX76_RS08835	COG1960	acyl-CoA dehydrogenase activity
GRX76_RS08865	COG0730	response to heat
GRX76_RS08880	COG0069	glutamate synthase activity
GRX76_RS08885	COG0025	NhaP-type Na H and K H
GRX76_RS08915	COG0259	pyridoxamine-phosphate oxidase activity
GRX76_RS08920	COG1960	acyl-CoA dehydrogenase activity
GRX76_RS08925	COG1960	acyl-CoA dehydrogenase activity
GRX76_RS08940	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GRX76_RS08945	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GRX76_RS08950	COG1570	exodeoxyribonuclease VII activity
GRX76_RS08960	COG0519	Catalyzes the synthesis of GMP from XMP
GRX76_RS08960	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GRX76_RS08970	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GRX76_RS08985	COG1178	ABC-type Fe3 transport system permease component
GRX76_RS08990	COG3842	ATPase activity
GRX76_RS08995	COG2885	chlorophyll binding
GRX76_RS09000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GRX76_RS09010	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GRX76_RS09015	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GRX76_RS09025	COG2350	Protein conserved in bacteria
GRX76_RS09035	COG0613	PHP domain protein
GRX76_RS09040	COG0009	L-threonylcarbamoyladenylate synthase
GRX76_RS09050	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GRX76_RS09065	COG2205	protein histidine kinase activity
GRX76_RS09070	COG0745	RESPONSE REGULATOR receiver
GRX76_RS09080	COG0716	FMN binding
GRX76_RS09090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GRX76_RS09095	COG2171	N-acyltransferase activity
GRX76_RS09100	COG1393	Belongs to the ArsC family
GRX76_RS09105	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GRX76_RS09115	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GRX76_RS09120	COG0024	Methionine aminopeptidase
GRX76_RS09125	COG0052	Belongs to the universal ribosomal protein uS2 family
GRX76_RS09130	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GRX76_RS09135	COG0528	UMP kinase activity
GRX76_RS09140	COG0233	cytoplasmic translational termination
GRX76_RS09145	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GRX76_RS09150	COG0575	Belongs to the CDS family
GRX76_RS09155	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GRX76_RS09165	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GRX76_RS09175	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GRX76_RS09180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GRX76_RS09185	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GRX76_RS09190	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GRX76_RS09195	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GRX76_RS09200	COG4536	flavin adenine dinucleotide binding
GRX76_RS09205	COG4137	Cytochrome C assembly protein
GRX76_RS09210	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GRX76_RS09215	COG0228	four-way junction DNA binding
GRX76_RS09220	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GRX76_RS09225	COG0336	Belongs to the RNA methyltransferase TrmD family
GRX76_RS09230	COG0335	large ribosomal subunit rRNA binding
GRX76_RS09240	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GRX76_RS09255	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GRX76_RS09265	COG1280	lysine exporter protein (LysE YggA)
GRX76_RS09280	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GRX76_RS09285	COG2137	regulation of response to DNA damage stimulus
GRX76_RS09300	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GRX76_RS09305	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GRX76_RS09315	COG2835	tetraacyldisaccharide 4'-kinase activity
GRX76_RS09320	COG0537	adenosine 5'-monophosphoramidase activity
GRX76_RS09325	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GRX76_RS09330	COG0527	aspartate kinase activity
GRX76_RS09335	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GRX76_RS09375	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GRX76_RS09380	COG0343	queuine tRNA-ribosyltransferase activity
GRX76_RS09390	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GRX76_RS09410	COG0418	dihydroorotase activity
GRX76_RS09415	COG0137	argininosuccinate synthase activity
GRX76_RS09420	COG3278	Belongs to the heme-copper respiratory oxidase family
GRX76_RS09435	COG2010	Cytochrome c
GRX76_RS09480	COG0463	Glycosyl transferase, family 2
GRX76_RS09500	COG3023	N-Acetylmuramoyl-L-alanine amidase
GRX76_RS09505	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GRX76_RS09515	COG1881	PFAM PEBP family protein
GRX76_RS09525	COG3695	enzyme binding
GRX76_RS09535	COG1028	Short-chain dehydrogenase reductase Sdr
GRX76_RS09540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GRX76_RS09550	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GRX76_RS09555	COG0459	protein refolding
GRX76_RS09635	COG0387	Pfam Sodium calcium exchanger
GRX76_RS09660	COG0587	DNA-directed DNA polymerase activity
GRX76_RS09675	COG0717	Belongs to the dCTP deaminase family
GRX76_RS09680	COG2081	HI0933 family
GRX76_RS09695	COG3530	Putative quorum-sensing-regulated virulence factor
GRX76_RS09725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GRX76_RS09740	COG2009	succinate dehydrogenase
GRX76_RS09745	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GRX76_RS09750	COG1053	succinate dehydrogenase
GRX76_RS09755	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GRX76_RS09770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GRX76_RS09775	COG0045	succinate-CoA ligase (ADP-forming) activity
GRX76_RS09810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GRX76_RS09820	COG5016	pyruvate
GRX76_RS09820	COG0511	ligase activity, forming carbon-carbon bonds
GRX76_RS09825	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GRX76_RS09835	COG0271	Belongs to the BolA IbaG family
GRX76_RS09840	COG3047	cAMP biosynthetic process
GRX76_RS09850	COG0789	Transcriptional regulator
GRX76_RS09855	COG0530	calcium, potassium:sodium antiporter activity
GRX76_RS09870	COG0514	ATP-dependent DNA helicase (RecQ)
GRX76_RS09895	COG0716	FMN binding
GRX76_RS09900	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GRX76_RS09930	COG0425	Belongs to the sulfur carrier protein TusA family
GRX76_RS09940	COG3101	peptidyl-lysine hydroxylation
GRX76_RS09945	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GRX76_RS09945	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GRX76_RS09950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GRX76_RS09970	COG0436	Aminotransferase
GRX76_RS09975	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GRX76_RS10005	COG1131	(ABC) transporter
GRX76_RS10010	COG0842	Transport permease protein
GRX76_RS10015	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GRX76_RS10015	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GRX76_RS10020	COG0745	RESPONSE REGULATOR receiver
GRX76_RS10025	COG2205	protein histidine kinase activity
GRX76_RS10065	COG3023	N-Acetylmuramoyl-L-alanine amidase
GRX76_RS10080	COG4948	Mandelate Racemase Muconate Lactonizing
GRX76_RS10100	COG1619	proteins homologs of microcin C7 resistance protein MccF
GRX76_RS10105	COG1757	Na H antiporter
GRX76_RS10115	COG1940	carbohydrate kinase activity
GRX76_RS10120	COG0738	Major facilitator superfamily
GRX76_RS10160	COG4677	pectinesterase activity
GRX76_RS10170	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GRX76_RS10175	COG0750	zinc metalloprotease
GRX76_RS10185	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GRX76_RS10195	COG4681	YaeQ
GRX76_RS10200	COG1666	GTP binding
GRX76_RS10210	COG1573	uracil-dna glycosylase
GRX76_RS10215	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GRX76_RS10225	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GRX76_RS10255	COG3086	response to oxidative stress
GRX76_RS10260	COG4948	Mandelate Racemase Muconate Lactonizing
GRX76_RS10265	COG2866	Carboxypeptidase
GRX76_RS10270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GRX76_RS10275	COG0481	GTPase activity
GRX76_RS10290	COG0571	ribonuclease III activity
GRX76_RS10295	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GRX76_RS10300	COG1381	Involved in DNA repair and RecF pathway recombination
GRX76_RS10305	COG2205	protein histidine kinase activity
GRX76_RS10305	COG0784	Response regulator, receiver
GRX76_RS10305	COG5002	protein histidine kinase activity
GRX76_RS10315	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GRX76_RS10320	COG3956	TIGRFAM MazG family protein
GRX76_RS10325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GRX76_RS10330	COG0563	adenylate kinase activity
GRX76_RS10335	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GRX76_RS10345	COG1214	PFAM Peptidase M22, glycoprotease
GRX76_RS10355	COG2084	Dehydrogenase
GRX76_RS10365	COG0180	Tryptophanyl-tRNA synthetase
GRX76_RS10390	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GRX76_RS10395	COG2974	May be involved in recombination
GRX76_RS10405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GRX76_RS10410	COG2195	Cleaves the N-terminal amino acid of tripeptides
GRX76_RS10415	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GRX76_RS10435	COG2968	Membrane
GRX76_RS10445	COG0346	lactoylglutathione lyase activity
GRX76_RS10470	COG4206	TonB-dependent receptor
GRX76_RS10475	COG1288	antiporter activity
GRX76_RS10480	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GRX76_RS10500	COG0174	glutamine synthetase
GRX76_RS10530	COG0110	maltose O-acetyltransferase activity
GRX76_RS10535	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GRX76_RS10540	COG1522	sequence-specific DNA binding
GRX76_RS10565	COG0438	transferase activity, transferring glycosyl groups
GRX76_RS10575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GRX76_RS10590	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GRX76_RS10595	COG1028	Short-chain dehydrogenase reductase Sdr
GRX76_RS10605	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GRX76_RS10610	COG0402	S-adenosylhomocysteine deaminase activity
GRX76_RS10625	COG0077	Prephenate dehydratase
GRX76_RS10625	COG1605	Chorismate mutase
GRX76_RS10630	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GRX76_RS10635	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GRX76_RS10645	COG0776	regulation of translation
GRX76_RS10655	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GRX76_RS10665	COG1555	photosystem II stabilization
GRX76_RS10675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GRX76_RS10695	COG0556	nucleotide-excision repair
GRX76_RS10705	COG1305	Transglutaminase-like
GRX76_RS10715	COG2308	Evidence 4 Homologs of previously reported genes of
GRX76_RS10720	COG0697	spore germination
GRX76_RS10730	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GRX76_RS10735	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GRX76_RS10740	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GRX76_RS10745	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GRX76_RS10750	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GRX76_RS10755	COG0072	phenylalanine-tRNA ligase activity
GRX76_RS10760	COG0776	regulation of translation
GRX76_RS10850	COG3645	SOS response
GRX76_RS11060	COG1987	bacterial-type flagellum assembly
GRX76_RS11065	COG1684	flagellar biosynthetic protein fliR
GRX76_RS11070	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GRX76_RS11075	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GRX76_RS11085	COG4786	Flagellar basal body rod
GRX76_RS11095	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GRX76_RS11100	COG1706	bacterial-type flagellum-dependent cell motility
GRX76_RS11115	COG1677	Flagellar hook-basal body complex protein FliE
GRX76_RS11120	COG1766	The M ring may be actively involved in energy transduction
GRX76_RS11145	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GRX76_RS11180	COG0596	Alpha beta hydrolase
GRX76_RS11185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GRX76_RS11190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GRX76_RS11215	COG1028	Short-chain dehydrogenase reductase Sdr
GRX76_RS11235	COG1960	acyl-CoA dehydrogenase activity
GRX76_RS11240	COG1012	belongs to the aldehyde dehydrogenase family
GRX76_RS11245	COG2267	carboxylic ester hydrolase activity
GRX76_RS11250	COG1335	isochorismatase
GRX76_RS11275	COG4771	TonB-dependent receptor
GRX76_RS11285	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GRX76_RS11315	COG0477	Major facilitator Superfamily
GRX76_RS11330	COG4221	oxidoreductase activity
GRX76_RS11345	COG4771	TonB-dependent receptor
GRX76_RS11395	COG2226	methyltransferase
GRX76_RS11420	COG0154	amidase activity
GRX76_RS11425	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GRX76_RS11430	COG1024	Enoyl-CoA hydratase
GRX76_RS11440	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GRX76_RS11455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GRX76_RS11460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GRX76_RS11465	COG2188	Transcriptional regulator
GRX76_RS11480	COG1335	isochorismatase
GRX76_RS11495	COG2301	Belongs to the HpcH HpaI aldolase family
GRX76_RS11500	COG2030	dehydratase
GRX76_RS11505	COG1960	acyl-CoA dehydrogenase activity
GRX76_RS11510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GRX76_RS11515	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GRX76_RS11520	COG2153	protein acetylation
GRX76_RS11525	COG1690	Belongs to the RtcB family
GRX76_RS11540	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GRX76_RS11555	COG1611	Belongs to the LOG family
GRX76_RS11565	COG0737	Belongs to the 5'-nucleotidase family
GRX76_RS11585	COG1842	Phage shock protein A
GRX76_RS11605	COG5463	Belongs to the UPF0441 family
GRX76_RS11610	COG0754	glutathionylspermidine amidase activity
GRX76_RS11620	COG3012	SEC-C Motif Domain Protein
GRX76_RS11630	COG0784	Response regulator, receiver
GRX76_RS11630	COG4191	Histidine kinase
GRX76_RS11635	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GRX76_RS11645	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GRX76_RS11695	COG0625	glutathione transferase activity
GRX76_RS11705	COG1448	Aminotransferase
GRX76_RS11710	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
GRX76_RS11715	COG0625	glutathione transferase activity
GRX76_RS11720	COG0339	signal peptide processing
GRX76_RS11730	COG1522	sequence-specific DNA binding
GRX76_RS11745	COG1595	DNA-templated transcription, initiation
GRX76_RS11755	COG4221	oxidoreductase activity
GRX76_RS11770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GRX76_RS11800	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GRX76_RS11800	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GRX76_RS11800	COG0506	proline dehydrogenase activity
GRX76_RS11825	COG0745	RESPONSE REGULATOR receiver
GRX76_RS11830	COG0642	Histidine kinase
GRX76_RS11845	COG1368	sulfuric ester hydrolase activity
GRX76_RS11855	COG1115	amino acid carrier protein
GRX76_RS11865	COG0023	Translation Initiation Factor
GRX76_RS11870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GRX76_RS11880	COG2900	Belongs to the SlyX family
GRX76_RS11905	COG0742	ribosomal rna small subunit methyltransferase
GRX76_RS11910	COG1760	l-serine dehydratase
GRX76_RS11915	COG0500	methyltransferase
GRX76_RS11920	COG4106	trans-aconitate 2-methyltransferase activity
GRX76_RS11935	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GRX76_RS11955	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GRX76_RS11980	COG1538	Outer membrane efflux protein
GRX76_RS11995	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GRX76_RS11995	COG4651	solute:proton antiporter activity
GRX76_RS12005	COG1522	sequence-specific DNA binding
GRX76_RS12015	COG3283	Transcriptional regulator of aromatic amino acids metabolism
GRX76_RS12025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GRX76_RS12035	COG1966	Carbon starvation protein
GRX76_RS12045	COG0003	Pfam Anion-transporting ATPase
GRX76_RS12055	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GRX76_RS12075	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GRX76_RS12075	COG0316	Belongs to the HesB IscA family
GRX76_RS12090	COG1643	Atp-dependent helicase
GRX76_RS12110	COG2375	cellular response to nickel ion
GRX76_RS12120	COG0500	methyltransferase
GRX76_RS12130	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GRX76_RS12225	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GRX76_RS12245	COG1322	Protein conserved in bacteria
GRX76_RS12260	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GRX76_RS12265	COG0432	Pfam Uncharacterised protein family UPF0047
GRX76_RS12285	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GRX76_RS12305	COG2920	part of a sulfur-relay system
GRX76_RS12320	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GRX76_RS12325	COG0670	Belongs to the BI1 family
GRX76_RS12340	COG0438	transferase activity, transferring glycosyl groups
GRX76_RS12350	COG0398	Pfam SNARE associated Golgi protein
GRX76_RS12370	COG1530	ribonuclease E activity
GRX76_RS12390	COG1399	metal-binding, possibly nucleic acid-binding protein
GRX76_RS12395	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GRX76_RS12400	COG0416	fatty acid biosynthetic process
GRX76_RS12405	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GRX76_RS12415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GRX76_RS12420	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GRX76_RS12430	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GRX76_RS12435	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GRX76_RS12450	COG0084	hydrolase, TatD family'
GRX76_RS12460	COG0039	L-malate dehydrogenase activity
GRX76_RS12465	COG0017	Asparaginyl-tRNA synthetase
GRX76_RS12475	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GRX76_RS12485	COG1862	Preprotein translocase
GRX76_RS12490	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GRX76_RS12495	COG1115	amino acid carrier protein
GRX76_RS12500	COG0174	glutamine synthetase
GRX76_RS12505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GRX76_RS12510	COG4774	siderophore transport
GRX76_RS12515	COG3226	Transcriptional regulator
GRX76_RS12570	COG0427	acetyl-CoA hydrolase
GRX76_RS12575	COG0280	phosphate acetyltransferase
GRX76_RS12575	COG0857	belongs to the CobB CobQ family
GRX76_RS12580	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GRX76_RS12600	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GRX76_RS12610	COG0642	Histidine kinase
GRX76_RS12615	COG0745	RESPONSE REGULATOR receiver
GRX76_RS12625	COG2153	protein acetylation
GRX76_RS12630	COG2850	peptidyl-arginine hydroxylation
GRX76_RS12640	COG2915	High frequency lysogenization protein hflD homolog
GRX76_RS12660	COG1278	Cold shock
GRX76_RS12665	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GRX76_RS12670	COG0542	response to heat
GRX76_RS12675	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GRX76_RS12680	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GRX76_RS12685	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GRX76_RS12690	COG0492	ferredoxin-NADP+ reductase activity
GRX76_RS12695	COG1674	ftsk spoiiie
GRX76_RS12700	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GRX76_RS12705	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GRX76_RS12710	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GRX76_RS12715	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GRX76_RS12720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GRX76_RS12720	COG1648	precorrin-2 dehydrogenase activity
GRX76_RS12730	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GRX76_RS12745	COG4771	TonB-dependent receptor
GRX76_RS12750	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GRX76_RS12765	COG0429	hydrolase of the alpha beta-hydrolase fold
GRX76_RS12775	COG1607	acyl-coa hydrolase
GRX76_RS12780	COG1309	transcriptional regulator
GRX76_RS12795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GRX76_RS12800	COG1116	anion transmembrane transporter activity
GRX76_RS12805	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GRX76_RS12845	COG1595	DNA-templated transcription, initiation
GRX76_RS12885	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GRX76_RS12895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GRX76_RS12900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GRX76_RS12905	COG1309	transcriptional regulator
GRX76_RS12910	COG0793	Belongs to the peptidase S41A family
GRX76_RS12915	COG0708	Exodeoxyribonuclease III
GRX76_RS12920	COG0640	Transcriptional regulator
GRX76_RS12930	COG0798	PFAM Bile acid sodium symporter
GRX76_RS12935	COG0431	NADPH-dependent FMN reductase
GRX76_RS12975	COG3156	type II secretion system protein K
GRX76_RS13060	COG3291	Pkd domain containing protein
GRX76_RS13065	COG3291	Pkd domain containing protein
GRX76_RS13085	COG0006	proline dipeptidase activity
GRX76_RS13090	COG2022	thiamine diphosphate biosynthetic process
GRX76_RS13090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GRX76_RS13095	COG0006	proline dipeptidase activity
GRX76_RS13100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GRX76_RS13120	COG1946	Acyl-CoA thioesterase
GRX76_RS13135	COG2423	ornithine cyclodeaminase activity
GRX76_RS13170	COG0322	excinuclease ABC activity
GRX76_RS13180	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GRX76_RS13185	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GRX76_RS13190	COG1663	tetraacyldisaccharide 4'-kinase activity
GRX76_RS13195	COG1132	(ABC) transporter
GRX76_RS13200	COG0848	biopolymer transport protein
GRX76_RS13205	COG0811	peptide transport
GRX76_RS13220	COG0658	competence protein
GRX76_RS13220	COG2333	competence protein COMEC
GRX76_RS13230	COG1944	ATP diphosphatase activity
GRX76_RS13245	COG3291	Pkd domain containing protein
GRX76_RS13285	COG3038	cytochrome b561
GRX76_RS13305	COG0417	DNA replication proofreading
GRX76_RS13370	COG0372	Belongs to the citrate synthase family
GRX76_RS13375	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GRX76_RS13380	COG1802	Transcriptional regulator
GRX76_RS13390	COG4591	ABC-type transport system involved in lipoprotein release permease component
GRX76_RS13400	COG4591	ABC-type transport system involved in lipoprotein release permease component
GRX76_RS13420	COG2050	protein possibly involved in aromatic compounds catabolism
GRX76_RS13425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GRX76_RS13435	COG1477	protein flavinylation
GRX76_RS13440	COG2871	sodium ion transport
GRX76_RS13445	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GRX76_RS13460	COG1805	sodium ion transport
GRX76_RS13465	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GRX76_RS13475	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GRX76_RS13490	COG1278	Cold shock
GRX76_RS13500	COG1472	Belongs to the glycosyl hydrolase 3 family
GRX76_RS13520	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GRX76_RS13545	COG0589	response to stress
GRX76_RS13555	COG0741	lytic transglycosylase activity
GRX76_RS13570	COG0631	protein serine/threonine phosphatase activity
GRX76_RS13580	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GRX76_RS13580	COG0116	Belongs to the methyltransferase superfamily
GRX76_RS13585	COG3130	regulation of translation
GRX76_RS13590	COG0167	dihydroorotate dehydrogenase activity
GRX76_RS13600	COG0714	Associated with various cellular activities
GRX76_RS13650	COG0175	sulfate reduction
GRX76_RS13665	COG1216	Glycosyl transferase, family 2
GRX76_RS13665	COG0438	transferase activity, transferring glycosyl groups
GRX76_RS13695	COG0438	transferase activity, transferring glycosyl groups
GRX76_RS13695	COG1216	Glycosyl transferase, family 2
GRX76_RS13720	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GRX76_RS13770	COG0529	Catalyzes the synthesis of activated sulfate
GRX76_RS13790	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GRX76_RS13795	COG1187	pseudouridine synthase activity
GRX76_RS13815	COG1956	GAF domain-containing protein
GRX76_RS13845	COG0215	cysteine-tRNA ligase activity
GRX76_RS13850	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GRX76_RS13855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GRX76_RS13860	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GRX76_RS13870	COG0659	secondary active sulfate transmembrane transporter activity
GRX76_RS13900	COG1597	lipid kinase activity
GRX76_RS13950	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GRX76_RS13955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GRX76_RS13960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GRX76_RS13975	COG0450	alkyl hydroperoxide reductase
GRX76_RS13985	COG0596	Alpha beta hydrolase
GRX76_RS13995	COG3122	Protein conserved in bacteria
GRX76_RS14005	COG0659	secondary active sulfate transmembrane transporter activity
GRX76_RS14020	COG0640	Transcriptional regulator
GRX76_RS14025	COG2391	methyltransferase activity
GRX76_RS14055	COG0604	alcohol dehydrogenase
GRX76_RS14060	COG0616	signal peptide processing
GRX76_RS14070	COG2816	NAD+ diphosphatase activity
GRX76_RS14080	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GRX76_RS14085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GRX76_RS14090	COG0328	RNA-DNA hybrid ribonuclease activity
GRX76_RS14095	COG2226	methyltransferase
GRX76_RS14100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GRX76_RS14105	COG0741	lytic transglycosylase activity
GRX76_RS14105	COG1388	LysM domain
GRX76_RS14110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GRX76_RS14120	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GRX76_RS14125	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GRX76_RS14130	COG0740	serine-type endopeptidase activity
GRX76_RS14135	COG0544	peptidyl-prolyl cis-trans isomerase activity
GRX76_RS14145	COG0183	Belongs to the thiolase family
GRX76_RS14160	COG4977	sequence-specific DNA binding
GRX76_RS14160	COG1917	Cupin 2, conserved barrel domain protein
GRX76_RS14175	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GRX76_RS14205	COG3106	COG3106 Predicted ATPase
GRX76_RS14225	COG1047	Peptidyl-prolyl cis-trans
GRX76_RS14230	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GRX76_RS14235	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GRX76_RS14240	COG0084	hydrolase, TatD family'
GRX76_RS14255	COG0385	Bile acid
GRX76_RS14260	COG2072	flavoprotein involved in K transport
GRX76_RS14270	COG0433	COG0433 Predicted ATPase
GRX76_RS14285	COG2866	Carboxypeptidase
GRX76_RS14300	COG0318	PFAM AMP-dependent synthetase and ligase
GRX76_RS14310	COG1960	acyl-CoA dehydrogenase activity
GRX76_RS14335	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GRX76_RS14340	COG3115	cell septum assembly
GRX76_RS14355	COG3088	subunit of a heme lyase
GRX76_RS14455	COG1739	Uncharacterized protein family UPF0029
GRX76_RS14465	COG1138	Cytochrome C-type biogenesis protein
GRX76_RS14470	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GRX76_RS14485	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GRX76_RS14515	COG1446	asparaginase
GRX76_RS14530	COG1250	3-hydroxyacyl-CoA dehydrogenase
GRX76_RS14530	COG1024	Enoyl-CoA hydratase
GRX76_RS14535	COG0183	Belongs to the thiolase family
GRX76_RS14575	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GRX76_RS14610	COG1505	serine-type exopeptidase activity
GRX76_RS14615	COG0471	metal ion transport
GRX76_RS14635	COG3228	Belongs to the MtfA family
GRX76_RS14665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GRX76_RS14685	COG0783	Belongs to the Dps family
GRX76_RS14705	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GRX76_RS14710	COG0686	Belongs to the AlaDH PNT family
GRX76_RS14720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GRX76_RS14745	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GRX76_RS14760	COG0037	tRNA processing
GRX76_RS14770	COG4181	ATPase activity
GRX76_RS14775	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GRX76_RS14780	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GRX76_RS14805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GRX76_RS14830	COG0183	Belongs to the thiolase family
GRX76_RS14835	COG1028	Short-chain dehydrogenase reductase Sdr
GRX76_RS14850	COG1028	Short-chain dehydrogenase reductase Sdr
GRX76_RS14875	COG1902	pentaerythritol trinitrate reductase activity
GRX76_RS14875	COG0446	pyridine nucleotide-disulphide oxidoreductase
GRX76_RS14910	COG2274	protein secretion by the type I secretion system
GRX76_RS14925	COG2211	Major facilitator Superfamily
GRX76_RS14930	COG2272	Belongs to the type-B carboxylesterase lipase family
GRX76_RS14940	COG0308	aminopeptidase N
GRX76_RS14945	COG0405	Gamma-glutamyltransferase
GRX76_RS14980	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GRX76_RS14985	COG0585	pseudouridine synthase activity
GRX76_RS14990	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GRX76_RS14995	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GRX76_RS15000	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GRX76_RS15005	COG0148	phosphopyruvate hydratase activity
GRX76_RS15015	COG0504	CTP synthase activity
GRX76_RS15040	COG1472	Belongs to the glycosyl hydrolase 3 family
GRX76_RS15050	COG0477	Major facilitator Superfamily
GRX76_RS15065	COG1307	EDD domain protein, DegV family
GRX76_RS15090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GRX76_RS15105	COG0318	PFAM AMP-dependent synthetase and ligase
GRX76_RS15115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GRX76_RS15125	COG2207	Transcriptional regulator
GRX76_RS15155	COG1063	alcohol dehydrogenase
GRX76_RS15160	COG4771	TonB-dependent receptor
GRX76_RS15170	COG3119	arylsulfatase activity
GRX76_RS15180	COG0714	Associated with various cellular activities
GRX76_RS15200	COG2304	oxidoreductase activity
GRX76_RS15215	COG3119	arylsulfatase activity
GRX76_RS15220	COG3119	arylsulfatase activity
GRX76_RS15225	COG3119	arylsulfatase activity
GRX76_RS15240	COG3119	arylsulfatase activity
GRX76_RS15275	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GRX76_RS15280	COG3507	Belongs to the glycosyl hydrolase 43 family
GRX76_RS15295	COG0277	FAD linked oxidase domain protein
GRX76_RS15335	COG1294	oxidase, subunit
GRX76_RS15340	COG4890	Cyd operon protein YbgT
GRX76_RS15350	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GRX76_RS15355	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GRX76_RS15435	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GRX76_RS15435	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GRX76_RS15460	COG2010	Cytochrome c
GRX76_RS15485	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GRX76_RS15490	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GRX76_RS15500	COG2067	long-chain fatty acid transport protein
GRX76_RS15505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GRX76_RS15505	COG1116	anion transmembrane transporter activity
GRX76_RS15510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GRX76_RS15515	COG1116	anion transmembrane transporter activity
GRX76_RS15535	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GRX76_RS15565	COG1012	belongs to the aldehyde dehydrogenase family
GRX76_RS15590	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GRX76_RS15595	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GRX76_RS15600	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GRX76_RS15605	COG0825	malonyl-CoA metabolic process
GRX76_RS15810	COG5265	(ABC) transporter
GRX76_RS15845	COG2235	arginine
GRX76_RS15860	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GRX76_RS15860	COG3323	Protein of unknown function (DUF1653)
GRX76_RS15865	COG3118	belongs to the thioredoxin family
GRX76_RS15870	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GRX76_RS15880	COG0583	DNA-binding transcription factor activity
GRX76_RS15895	COG1454	alcohol dehydrogenase
GRX76_RS15905	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GRX76_RS15910	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GRX76_RS15915	COG2315	Protein conserved in bacteria
GRX76_RS15935	COG0583	DNA-binding transcription factor activity
GRX76_RS15940	COG0431	NADPH-dependent FMN reductase
GRX76_RS15950	COG0590	tRNA wobble adenosine to inosine editing
GRX76_RS15955	COG2226	methyltransferase
GRX76_RS15980	COG0795	lipopolysaccharide-transporting ATPase activity
GRX76_RS15990	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GRX76_RS16005	COG0525	valine-tRNA ligase activity
GRX76_RS16010	COG0189	ligase activity
GRX76_RS16030	COG1199	ATP-dependent helicase activity
GRX76_RS16050	COG0166	Belongs to the GPI family
GRX76_RS16085	COG3291	Pkd domain containing protein
GRX76_RS16095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GRX76_RS16100	COG1702	phosphate starvation-inducible protein PhoH
GRX76_RS16110	COG4535	Mg2 and Co2 transporter CorC
GRX76_RS16115	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GRX76_RS16120	COG1090	epimerase
GRX76_RS16140	COG0495	leucyl-tRNA aminoacylation
GRX76_RS16150	COG1466	dna polymerase III delta subunit
GRX76_RS16160	COG1960	acyl-CoA dehydrogenase activity
GRX76_RS16170	COG4942	peptidase
GRX76_RS16185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GRX76_RS16225	COG4774	siderophore transport
GRX76_RS16240	COG1982	Orn Lys Arg decarboxylase major
GRX76_RS16270	COG0456	acetyltransferase
GRX76_RS16280	COG0288	reversible hydration of carbon dioxide
GRX76_RS16290	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GRX76_RS16305	COG0709	Synthesizes selenophosphate from selenide and ATP
GRX76_RS16310	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
GRX76_RS16330	COG0436	Aminotransferase
GRX76_RS16335	COG0154	amidase activity
GRX76_RS16355	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GRX76_RS16365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GRX76_RS16370	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GRX76_RS16385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GRX76_RS16400	COG0753	catalase activity
GRX76_RS16415	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GRX76_RS16425	COG2921	Belongs to the UPF0250 family
GRX76_RS16430	COG1686	Belongs to the peptidase S11 family
GRX76_RS16440	COG2951	lytic endotransglycosylase activity
GRX76_RS16445	COG0772	Belongs to the SEDS family
GRX76_RS16450	COG0768	penicillin binding
GRX76_RS16455	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GRX76_RS16465	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GRX76_RS16470	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GRX76_RS16485	COG2321	neutral zinc metallopeptidase
GRX76_RS16490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GRX76_RS16505	COG1530	ribonuclease E activity
GRX76_RS16520	COG1792	Involved in formation and maintenance of cell shape
GRX76_RS16525	COG1077	Cell shape determining protein MreB Mrl
GRX76_RS16530	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GRX76_RS16535	COG0154	amidase activity
GRX76_RS16540	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GRX76_RS16545	COG0154	amidase activity
GRX76_RS16570	COG0534	Mate efflux family protein
GRX76_RS16580	COG1725	Transcriptional regulator
GRX76_RS16600	COG1230	cation diffusion facilitator family transporter
GRX76_RS16605	COG2890	protein-(glutamine-N5) methyltransferase activity
GRX76_RS16610	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GRX76_RS16625	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GRX76_RS16630	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GRX76_RS16640	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GRX76_RS16645	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GRX76_RS16650	COG0193	aminoacyl-tRNA hydrolase activity
GRX76_RS16700	COG0469	pyruvate kinase activity
GRX76_RS16710	COG0800	Aldolase
GRX76_RS16720	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GRX76_RS16725	COG0129	dihydroxy-acid dehydratase activity
GRX76_RS16730	COG0166	Belongs to the GPI family
GRX76_RS16735	COG1609	Transcriptional regulator
GRX76_RS16740	COG0738	Major facilitator superfamily
GRX76_RS16745	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GRX76_RS16750	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GRX76_RS16755	COG2971	BadF BadG BcrA BcrD
GRX76_RS16760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GRX76_RS16770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GRX76_RS16775	COG0540	Belongs to the ATCase OTCase family
GRX76_RS16780	COG2925	Exonuclease
GRX76_RS16800	COG0018	arginyl-trna synthetase
GRX76_RS16815	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GRX76_RS16815	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GRX76_RS16835	COG0788	formyltetrahydrofolate deformylase activity
GRX76_RS16840	COG0006	proline dipeptidase activity
GRX76_RS16855	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GRX76_RS16860	COG0583	DNA-binding transcription factor activity
GRX76_RS16865	COG3128	pkhd-type hydroxylase
GRX76_RS16870	COG4774	siderophore transport
GRX76_RS16880	COG0513	Belongs to the DEAD box helicase family
GRX76_RS16890	COG4464	protein tyrosine phosphatase activity
GRX76_RS16895	COG0489	protein tyrosine kinase activity
GRX76_RS16910	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GRX76_RS16935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GRX76_RS16945	COG3551	Protein conserved in bacteria
GRX76_RS16970	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GRX76_RS16985	COG0463	Glycosyl transferase, family 2
GRX76_RS16985	COG1216	Glycosyl transferase, family 2
GRX76_RS17005	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GRX76_RS17040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GRX76_RS17085	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GRX76_RS17100	COG0745	RESPONSE REGULATOR receiver
GRX76_RS17105	COG2853	Lipoprotein
GRX76_RS17115	COG3220	belongs to the UPF0276 family
GRX76_RS17125	COG1643	Atp-dependent helicase
GRX76_RS17130	COG3104	oligopeptide transport
GRX76_RS17135	COG0739	heme binding
GRX76_RS17135	COG1196	nuclear chromosome segregation
GRX76_RS17135	COG0741	lytic transglycosylase activity
GRX76_RS17160	COG1522	sequence-specific DNA binding
GRX76_RS17170	COG3240	lipase activity
GRX76_RS17170	COG4625	pathogenesis
GRX76_RS17180	COG0415	Belongs to the DNA photolyase family
GRX76_RS17190	COG0277	FAD linked oxidase domain protein
GRX76_RS17190	COG0247	lactate metabolic process
GRX76_RS17235	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GRX76_RS17235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GRX76_RS17240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GRX76_RS17260	COG3707	response regulator
GRX76_RS17265	COG2116	formate transmembrane transporter activity
GRX76_RS17270	COG0515	serine threonine protein kinase
GRX76_RS17275	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
GRX76_RS17280	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GRX76_RS17285	COG0625	glutathione transferase activity
GRX76_RS17290	COG0454	-acetyltransferase
GRX76_RS17300	COG4657	Part of a membrane complex involved in electron transport
GRX76_RS17305	COG2878	Part of a membrane complex involved in electron transport
GRX76_RS17315	COG4658	electron transport chain
GRX76_RS17320	COG4659	FMN binding
GRX76_RS17325	COG4660	Part of a membrane complex involved in electron transport
GRX76_RS17335	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GRX76_RS17340	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GRX76_RS17360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GRX76_RS17390	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GRX76_RS17430	COG4783	chaperone-mediated protein folding
GRX76_RS17440	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GRX76_RS17445	COG3483	tryptophan 2,3-dioxygenase activity
GRX76_RS17450	COG0848	biopolymer transport protein
GRX76_RS17455	COG1803	Methylglyoxal synthase
GRX76_RS17475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GRX76_RS17490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GRX76_RS17500	COG3590	peptidase
GRX76_RS17505	COG0477	Major facilitator Superfamily
GRX76_RS17540	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GRX76_RS17555	COG0534	Mate efflux family protein
GRX76_RS17570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GRX76_RS17575	COG1846	Transcriptional regulator
GRX76_RS17580	COG0386	Belongs to the glutathione peroxidase family
GRX76_RS17615	COG1183	phosphatidylcholine synthase activity
GRX76_RS17620	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GRX76_RS17630	COG0028	Belongs to the TPP enzyme family
GRX76_RS17640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GRX76_RS17645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GRX76_RS17670	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GRX76_RS17670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GRX76_RS17720	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GRX76_RS17725	COG1047	Peptidyl-prolyl cis-trans
GRX76_RS17730	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GRX76_RS17735	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GRX76_RS17740	COG0196	riboflavin kinase activity
GRX76_RS17760	COG0745	RESPONSE REGULATOR receiver
GRX76_RS17765	COG2205	protein histidine kinase activity
GRX76_RS17770	COG0268	Binds directly to 16S ribosomal RNA
GRX76_RS17775	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GRX76_RS17780	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GRX76_RS17785	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GRX76_RS17790	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GRX76_RS17795	COG0142	geranyltranstransferase activity
GRX76_RS17810	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GRX76_RS17830	COG2814	Major facilitator Superfamily
GRX76_RS17850	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GRX76_RS17855	COG1984	allophanate hydrolase subunit 2
GRX76_RS17865	COG3139	Protein of unknown function (DUF1315)
GRX76_RS17870	COG0203	ribosomal protein L17
GRX76_RS17875	COG0202	RNA polymerase activity
GRX76_RS17880	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GRX76_RS17885	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GRX76_RS17890	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GRX76_RS17895	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GRX76_RS17905	COG0200	Binds to the 23S rRNA
GRX76_RS17910	COG1841	ribosomal large subunit assembly
GRX76_RS17915	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GRX76_RS17920	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GRX76_RS17925	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GRX76_RS17930	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GRX76_RS17935	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GRX76_RS17940	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GRX76_RS17945	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GRX76_RS17950	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GRX76_RS17955	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GRX76_RS17960	COG0255	Belongs to the universal ribosomal protein uL29 family
GRX76_RS17965	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GRX76_RS17970	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GRX76_RS17975	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GRX76_RS17980	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GRX76_RS17985	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GRX76_RS17990	COG0089	rRNA binding
GRX76_RS17995	COG0088	Forms part of the polypeptide exit tunnel
GRX76_RS18000	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GRX76_RS18005	COG0051	transcription antitermination factor activity, RNA binding
GRX76_RS18040	COG0515	serine threonine protein kinase
GRX76_RS18055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GRX76_RS18060	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GRX76_RS18065	COG0049	tRNA binding
GRX76_RS18070	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GRX76_RS18075	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GRX76_RS18080	COG0085	RNA polymerase activity
GRX76_RS18085	COG0222	ribosome binding
GRX76_RS18090	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GRX76_RS18095	COG0081	regulation of translation
GRX76_RS18100	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GRX76_RS18120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GRX76_RS18150	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GRX76_RS18155	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GRX76_RS18155	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GRX76_RS18160	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GRX76_RS18165	COG1668	transmembrane transport
GRX76_RS18170	COG1131	(ABC) transporter
GRX76_RS18185	COG4989	oxidoreductase activity
GRX76_RS18210	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GRX76_RS18220	COG2095	MarC family integral membrane protein
GRX76_RS18225	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
GRX76_RS18240	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GRX76_RS18250	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GRX76_RS18260	COG2814	Major facilitator Superfamily
GRX76_RS18265	COG1566	PFAM secretion protein HlyD family protein
GRX76_RS18275	COG2233	PERMEase
GRX76_RS18310	COG2409	Drug exporters of the RND superfamily
GRX76_RS18325	COG1116	anion transmembrane transporter activity
GRX76_RS18330	COG0390	transport system, permease component
GRX76_RS18340	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GRX76_RS18350	COG0709	Synthesizes selenophosphate from selenide and ATP
GRX76_RS18360	COG1252	NADH dehydrogenase
GRX76_RS18390	COG0471	metal ion transport
GRX76_RS18390	COG3273	potassium ion transport
GRX76_RS18395	COG0300	oxidoreductase activity
GRX76_RS18425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GRX76_RS18470	COG1172	Belongs to the binding-protein-dependent transport system permease family
GRX76_RS18480	COG1472	Belongs to the glycosyl hydrolase 3 family
GRX76_RS18495	COG0366	Alpha amylase catalytic
GRX76_RS18530	COG1115	amino acid carrier protein
GRX76_RS18545	COG2190	(PTS) system
GRX76_RS18545	COG2211	Major facilitator Superfamily
GRX76_RS18625	COG0366	Alpha amylase catalytic
GRX76_RS18630	COG1501	Belongs to the glycosyl hydrolase 31 family
GRX76_RS18635	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GRX76_RS18660	COG0642	Histidine kinase
GRX76_RS18665	COG0745	RESPONSE REGULATOR receiver
GRX76_RS18675	COG1028	Short-chain dehydrogenase reductase Sdr
GRX76_RS18695	COG0366	Alpha amylase catalytic
GRX76_RS18705	COG2133	pyrroloquinoline quinone binding
GRX76_RS18710	COG5001	Diguanylate cyclase
GRX76_RS18710	COG3706	GGDEF domain
GRX76_RS18710	COG4251	negative regulation of phosphorylation
GRX76_RS18710	COG2203	Gaf domain
GRX76_RS18715	COG0366	Alpha amylase catalytic
GRX76_RS18720	COG0589	response to stress
GRX76_RS18740	COG0837	glucose binding
GRX76_RS18780	COG1472	Belongs to the glycosyl hydrolase 3 family
GRX76_RS18840	COG1082	Xylose isomerase domain protein TIM barrel
GRX76_RS18850	COG1609	Transcriptional regulator
GRX76_RS18860	COG3833	ABC-type maltose transport systems, permease component
GRX76_RS18905	COG4774	siderophore transport
GRX76_RS18925	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GRX76_RS18930	COG4206	TonB-dependent receptor
GRX76_RS18935	COG1120	ATPase activity
GRX76_RS18940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GRX76_RS18955	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GRX76_RS18990	COG4771	TonB-dependent receptor
GRX76_RS19000	COG2871	sodium ion transport
GRX76_RS19015	COG2132	Multicopper oxidase
GRX76_RS19050	COG2217	Heavy metal translocating P-type atpase
GRX76_RS19105	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA